{"text_format":"3","workbook":"xlsx","n_sheets":2,"sheets":["General Information","L4000-Neuronal-1737 cpds"],"not_rendered":{"images":2,"defined_names":1},"read":"whole","date_system":"1900"}

{"sheet":"General Information","index":0,"n_rows":535,"n_cols":14,"rows_kept":535,"merged":[[0,3,0,13],[1,1,1,13],[2,0,2,13],[3,1,3,13],[4,1,4,2],[4,3,4,13],[5,1,5,2],[5,3,5,13],[6,1,7,2],[6,3,6,13],[7,3,7,13],[8,1,8,2],[8,3,8,13],[9,1,11,2],[9,3,9,13],[10,3,10,13],[11,3,11,13],[14,1,14,13],[16,1,17,1],[16,2,17,2],[16,13,17,13],[18,1,19,1],[18,2,19,2],[18,13,19,13],[20,1,21,1],[20,2,21,2],[20,13,21,13],[22,1,23,1],[22,2,23,2],[22,13,23,13],[24,1,25,1],[24,2,25,2],[24,13,25,13],[26,1,27,1],[26,2,27,2],[26,13,27,13],[28,1,29,1],[28,2,29,2],[28,13,29,13],[30,1,31,1],[30,2,31,2],[30,13,31,13],[35,1,35,13],[37,1,38,1],[37,2,38,2],[37,13,38,13],[39,1,40,1],[39,2,40,2],[39,13,40,13],[41,1,42,1],[41,2,42,2],[41,13,42,13],[43,1,44,1],[43,2,44,2],[43,13,44,13],[45,1,46,1],[45,2,46,2],[45,13,46,13],[47,1,48,1],[47,2,48,2],[47,13,48,13],[49,1,50,1],[49,2,50,2],[49,13,50,13],[51,1,52,1],[51,2,52,2],[51,13,52,13],[56,1,56,13],[58,1,59,1],[58,2,59,2],[58,13,59,13],[60,1,61,1],[60,2,61,2],[60,13,61,13],[62,1,63,1],[62,2,63,2],[62,13,63,13],[64,1,65,1],[64,2,65,2],[64,13,65,13],[66,1,67,1],[66,2,67,2],[66,13,67,13],[68,1,69,1],[68,2,69,2],[68,13,69,13],[70,1,71,1],[70,2,71,2],[70,13,71,13],[72,1,73,1],[72,2,73,2],[72,13,73,13],[77,1,77,13],[79,1,80,1],[79,2,80,2],[79,13,80,13],[81,1,82,1],[81,2,82,2],[81,13,82,13],[83,1,84,1],[83,2,84,2],[83,13,84,13],[85,1,86,1],[85,2,86,2],[85,13,86,13],[87,1,88,1],[87,2,88,2],[87,13,88,13],[89,1,90,1],[89,2,90,2],[89,13,90,13],[91,1,92,1],[91,2,92,2],[91,13,92,13],[93,1,94,1],[93,2,94,2],[93,13,94,13],[98,1,98,13],[100,1,101,1],[100,2,101,2],[100,13,101,13],[102,1,103,1],[102,2,103,2],[102,13,103,13],[104,1,105,1],[104,2,105,2],[104,13,105,13],[106,1,107,1],[106,2,107,2],[106,13,107,13],[108,1,109,1],[108,2,109,2],[108,13,109,13],[110,1,111,1],[110,2,111,2],[110,13,111,13],[112,1,113,1],[112,2,113,2],[112,13,113,13],[114,1,115,1],[114,2,115,2],[114,13,115,13],[119,1,119,13],[121,1,122,1],[121,2,122,2],[121,13,122,13],[123,1,124,1],[123,2,124,2],[123,13,124,13],[125,1,126,1],[125,2,126,2],[125,13,126,13],[127,1,128,1],[127,2,128,2],[127,13,128,13],[129,1,130,1],[129,2,130,2],[129,13,130,13],[131,1,132,1],[131,2,132,2],[131,13,132,13],[133,1,134,1],[133,2,134,2],[133,13,134,13],[135,1,136,1],[135,2,136,2],[135,13,136,13],[140,1,140,13],[142,1,143,1],[142,2,143,2],[142,13,143,13],[144,1,145,1],[144,2,145,2],[144,13,145,13],[146,1,147,1],[146,2,147,2],[146,13,147,13],[148,1,149,1],[148,2,149,2],[148,13,149,13],[150,1,151,1],[150,2,151,2],[150,13,151,13],[152,1,153,1],[152,2,153,2],[152,13,153,13],[154,1,155,1],[154,2,155,2],[154,13,155,13],[156,1,157,1],[156,2,157,2],[156,13,157,13],[161,1,161,13],[163,1,164,1],[163,2,164,2],[163,13,164,13],[165,1,166,1],[165,2,166,2],[165,13,166,13],[167,1,168,1],[167,2,168,2],[167,13,168,13],[169,1,170,1],[169,2,170,2],[169,13,170,13],[171,1,172,1],[171,2,172,2],[171,13,172,13],[173,1,174,1],[173,2,174,2],[173,13,174,13],[175,1,176,1],[175,2,176,2],[175,13,176,13],[177,1,178,1],[177,2,178,2],[177,13,178,13],[182,1,182,13],[184,1,185,1],[184,2,185,2],[184,13,185,13],[186,1,187,1],[186,2,187,2],[186,13,187,13],[188,1,189,1],[188,2,189,2],[188,13,189,13],[190,1,191,1],[190,2,191,2],[190,13,191,13],[192,1,193,1],[192,2,193,2],[192,13,193,13],[194,1,195,1],[194,2,195,2],[194,13,195,13],[196,1,197,1],[196,2,197,2],[196,13,197,13],[198,1,199,1],[198,2,199,2],[198,13,199,13],[203,1,203,13],[205,1,206,1],[205,2,206,2],[205,13,206,13],[207,1,208,1],[207,2,208,2],[207,13,208,13],[209,1,210,1],[209,2,210,2],[209,13,210,13],[211,1,212,1],[211,2,212,2],[211,13,212,13],[213,1,214,1],[213,2,214,2],[213,13,214,13],[215,1,216,1],[215,2,216,2],[215,13,216,13],[217,1,218,1],[217,2,218,2],[217,13,218,13],[219,1,220,1],[219,2,220,2],[219,13,220,13],[224,1,224,13],[226,1,227,1],[226,2,227,2],[226,13,227,13],[228,1,229,1],[228,2,229,2],[228,13,229,13],[230,1,231,1],[230,2,231,2],[230,13,231,13],[232,1,233,1],[232,2,233,2],[232,13,233,13],[234,1,235,1],[234,2,235,2],[234,13,235,13],[236,1,237,1],[236,2,237,2],[236,13,237,13],[238,1,239,1],[238,2,239,2],[238,13,239,13],[240,1,241,1],[240,2,241,2],[240,13,241,13],[245,1,245,13],[247,1,248,1],[247,2,248,2],[247,13,248,13],[249,1,250,1],[249,2,250,2],[249,13,250,13],[251,1,252,1],[251,2,252,2],[251,13,252,13],[253,1,254,1],[253,2,254,2],[253,13,254,13],[255,1,256,1],[255,2,256,2],[255,13,256,13],[257,1,258,1],[257,2,258,2],[257,13,258,13],[259,1,260,1],[259,2,260,2],[259,13,260,13],[261,1,262,1],[261,2,262,2],[261,13,262,13],[266,1,266,13],[268,1,269,1],[268,2,269,2],[268,13,269,13],[270,1,271,1],[270,2,271,2],[270,13,271,13],[272,1,273,1],[272,2,273,2],[272,13,273,13],[274,1,275,1],[274,2,275,2],[274,13,275,13],[276,1,277,1],[276,2,277,2],[276,13,277,13],[278,1,279,1],[278,2,279,2],[278,13,279,13],[280,1,281,1],[280,2,281,2],[280,13,281,13],[282,1,283,1],[282,2,283,2],[282,13,283,13],[287,1,287,13],[289,1,290,1],[289,2,290,2],[289,13,290,13],[291,1,292,1],[291,2,292,2],[291,13,292,13],[293,1,294,1],[293,2,294,2],[293,13,294,13],[295,1,296,1],[295,2,296,2],[295,13,296,13],[297,1,298,1],[297,2,298,2],[297,13,298,13],[299,1,300,1],[299,2,300,2],[299,13,300,13],[301,1,302,1],[301,2,302,2],[301,13,302,13],[303,1,304,1],[303,2,304,2],[303,13,304,13],[308,1,308,13],[310,1,311,1],[310,2,311,2],[310,13,311,13],[312,1,313,1],[312,2,313,2],[312,13,313,13],[314,1,315,1],[314,2,315,2],[314,13,315,13],[316,1,317,1],[316,2,317,2],[316,13,317,13],[318,1,319,1],[318,2,319,2],[318,13,319,13],[320,1,321,1],[320,2,321,2],[320,13,321,13],[322,1,323,1],[322,2,323,2],[322,13,323,13],[324,1,325,1],[324,2,325,2],[324,13,325,13],[329,1,329,13],[331,1,332,1],[331,2,332,2],[331,13,332,13],[333,1,334,1],[333,2,334,2],[333,13,334,13],[335,1,336,1],[335,2,336,2],[335,13,336,13],[337,1,338,1],[337,2,338,2],[337,13,338,13],[339,1,340,1],[339,2,340,2],[339,13,340,13],[341,1,342,1],[341,2,342,2],[341,13,342,13],[343,1,344,1],[343,2,344,2],[343,13,344,13],[345,1,346,1],[345,2,346,2],[345,13,346,13],[350,1,350,13],[352,1,353,1],[352,2,353,2],[352,13,353,13],[354,1,355,1],[354,2,355,2],[354,13,355,13],[356,1,357,1],[356,2,357,2],[356,13,357,13],[358,1,359,1],[358,2,359,2],[358,13,359,13],[360,1,361,1],[360,2,361,2],[360,13,361,13],[362,1,363,1],[362,2,363,2],[362,13,363,13],[364,1,365,1],[364,2,365,2],[364,13,365,13],[366,1,367,1],[366,2,367,2],[366,13,367,13],[371,1,371,13],[373,1,374,1],[373,2,374,2],[373,13,374,13],[375,1,376,1],[375,2,376,2],[375,13,376,13],[377,1,378,1],[377,2,378,2],[377,13,378,13],[379,1,380,1],[379,2,380,2],[379,13,380,13],[381,1,382,1],[381,2,382,2],[381,13,382,13],[383,1,384,1],[383,2,384,2],[383,13,384,13],[385,1,386,1],[385,2,386,2],[385,13,386,13],[387,1,388,1],[387,2,388,2],[387,13,388,13],[392,1,392,13],[394,1,395,1],[394,2,395,2],[394,13,395,13],[396,1,397,1],[396,2,397,2],[396,13,397,13],[398,1,399,1],[398,2,399,2],[398,13,399,13],[400,1,401,1],[400,2,401,2],[400,13,401,13],[402,1,403,1],[402,2,403,2],[402,13,403,13],[404,1,405,1],[404,2,405,2],[404,13,405,13],[406,1,407,1],[406,2,407,2],[406,13,407,13],[408,1,409,1],[408,2,409,2],[408,13,409,13],[413,1,413,13],[415,1,416,1],[415,2,416,2],[415,13,416,13],[417,1,418,1],[417,2,418,2],[417,13,418,13],[419,1,420,1],[419,2,420,2],[419,13,420,13],[421,1,422,1],[421,2,422,2],[421,13,422,13],[423,1,424,1],[423,2,424,2],[423,13,424,13],[425,1,426,1],[425,2,426,2],[425,13,426,13],[427,1,428,1],[427,2,428,2],[427,13,428,13],[429,1,430,1],[429,2,430,2],[429,13,430,13],[434,1,434,13],[436,1,437,1],[436,2,437,2],[436,4,437,4],[436,5,437,5],[436,6,437,6],[436,7,437,7],[436,8,437,8],[436,9,437,9],[436,10,437,10],[436,11,437,11],[436,12,437,12],[436,13,437,13],[438,1,439,1],[438,2,439,2],[438,4,439,4],[438,5,439,5],[438,6,439,6],[438,7,439,7],[438,8,439,8],[438,9,439,9],[438,10,439,10],[438,11,439,11],[438,12,439,12],[438,13,439,13],[440,1,441,1],[440,2,441,2],[440,4,441,4],[440,5,441,5],[440,6,441,6],[440,7,441,7],[440,8,441,8],[440,9,441,9],[440,10,441,10],[440,11,441,11],[440,12,441,12],[440,13,441,13],[442,1,443,1],[442,2,443,2],[442,4,443,4],[442,5,443,5],[442,6,443,6],[442,7,443,7],[442,8,443,8],[442,9,443,9],[442,10,443,10],[442,11,443,11],[442,12,443,12],[442,13,443,13],[444,1,445,1],[444,2,445,2],[444,3,445,3],[444,4,445,4],[444,5,445,5],[444,6,445,6],[444,7,445,7],[444,8,445,8],[444,9,445,9],[444,10,445,10],[444,11,445,11],[444,12,445,12],[444,13,445,13],[446,1,447,1],[446,2,447,2],[446,3,447,3],[446,4,447,4],[446,5,447,5],[446,6,447,6],[446,7,447,7],[446,8,447,8],[446,9,447,9],[446,10,447,10],[446,11,447,11],[446,12,447,12],[446,13,447,13],[448,1,449,1],[448,2,449,2],[448,3,449,3],[448,4,449,4],[448,5,449,5],[448,6,449,6],[448,7,449,7],[448,8,449,8],[448,9,449,9],[448,10,449,10],[448,11,449,11],[448,12,449,12],[448,13,449,13],[450,1,451,1],[450,2,451,2],[450,3,451,3],[450,4,451,4],[450,5,451,5],[450,6,451,6],[450,7,451,7],[450,8,451,8],[450,9,451,9],[450,10,451,10],[450,11,451,11],[450,12,451,12],[450,13,451,13],[455,1,455,13],[457,1,458,1],[457,2,458,2],[457,13,458,13],[459,1,460,1],[459,2,460,2],[459,13,460,13],[461,1,462,1],[461,2,462,2],[461,13,462,13],[463,1,464,1],[463,2,464,2],[463,13,464,13],[465,1,466,1],[465,2,466,2],[465,13,466,13],[467,1,468,1],[467,2,468,2],[467,13,468,13],[469,1,470,1],[469,2,470,2],[469,13,470,13],[471,1,472,1],[471,2,472,2],[471,13,472,13],[476,1,476,13],[478,1,479,1],[478,2,479,2],[478,4,479,4],[478,5,479,5],[478,6,479,6],[478,7,479,7],[478,8,479,8],[478,9,479,9],[478,10,479,10],[478,11,479,11],[478,12,479,12],[478,13,479,13],[480,1,481,1],[480,2,481,2],[480,4,481,4],[480,5,481,5],[480,6,481,6],[480,7,481,7],[480,8,481,8],[480,9,481,9],[480,10,481,10],[480,11,481,11],[480,12,481,12],[480,13,481,13],[482,1,483,1],[482,2,483,2],[482,4,483,4],[482,5,483,5],[482,6,483,6],[482,7,483,7],[482,8,483,8],[482,9,483,9],[482,10,483,10],[482,11,483,11],[482,12,483,12],[482,13,483,13],[484,1,485,1],[484,2,485,2],[484,4,485,4],[484,5,485,5],[484,6,485,6],[484,7,485,7],[484,8,485,8],[484,9,485,9],[484,10,485,10],[484,11,485,11],[484,12,485,12],[484,13,485,13],[486,1,487,1],[486,2,487,2],[486,4,487,4],[486,5,487,5],[486,6,487,6],[486,7,487,7],[486,8,487,8],[486,9,487,9],[486,10,487,10],[486,11,487,11],[486,12,487,12],[486,13,487,13],[488,1,489,1],[488,2,489,2],[488,3,489,3],[488,4,489,4],[488,5,489,5],[488,6,489,6],[488,7,489,7],[488,8,489,8],[488,9,489,9],[488,10,489,10],[488,11,489,11],[488,12,489,12],[488,13,489,13],[490,1,491,1],[490,2,491,2],[490,3,491,3],[490,4,491,4],[490,5,491,5],[490,6,491,6],[490,7,491,7],[490,8,491,8],[490,9,491,9],[490,10,491,10],[490,11,491,11],[490,12,491,12],[490,13,491,13],[492,1,493,1],[492,2,493,2],[492,3,493,3],[492,4,493,4],[492,5,493,5],[492,6,493,6],[492,7,493,7],[492,8,493,8],[492,9,493,9],[492,10,493,10],[492,11,493,11],[492,12,493,12],[492,13,493,13],[497,1,497,13],[499,1,500,1],[499,2,500,2],[499,9,500,9],[499,10,500,10],[499,11,500,11],[499,12,500,12],[499,13,500,13],[501,1,502,1],[501,2,502,2],[501,9,502,9],[501,10,502,10],[501,11,502,11],[501,12,502,12],[501,13,502,13],[503,1,504,1],[503,2,504,2],[503,9,504,9],[503,10,504,10],[503,11,504,11],[503,12,504,12],[503,13,504,13],[505,1,506,1],[505,2,506,2],[505,8,506,8],[505,9,506,9],[505,10,506,10],[505,11,506,11],[505,12,506,12],[505,13,506,13],[507,1,508,1],[507,2,508,2],[507,8,508,8],[507,9,508,9],[507,10,508,10],[507,11,508,11],[507,12,508,12],[507,13,508,13],[509,1,510,1],[509,2,510,2],[509,8,510,8],[509,9,510,9],[509,10,510,10],[509,11,510,11],[509,12,510,12],[509,13,510,13],[511,1,512,1],[511,2,512,2],[511,8,512,8],[511,9,512,9],[511,10,512,10],[511,11,512,11],[511,12,512,12],[511,13,512,13],[513,1,514,1],[513,2,514,2],[513,8,514,8],[513,9,514,9],[513,10,514,10],[513,11,514,11],[513,12,514,12],[513,13,514,13],[518,1,518,13],[520,1,521,1],[520,2,521,2],[520,4,521,4],[520,5,521,5],[520,6,521,6],[520,7,521,7],[520,8,521,8],[520,9,521,9],[520,10,521,10],[520,11,521,11],[520,12,521,12],[520,13,521,13],[522,1,523,1],[522,2,523,2],[522,4,523,4],[522,5,523,5],[522,6,523,6],[522,7,523,7],[522,8,523,8],[522,9,523,9],[522,10,523,10],[522,11,523,11],[522,12,523,12],[522,13,523,13],[524,1,525,1],[524,2,525,2],[524,4,525,4],[524,5,525,5],[524,6,525,6],[524,7,525,7],[524,8,525,8],[524,9,525,9],[524,10,525,10],[524,11,525,11],[524,12,525,12],[524,13,525,13],[526,1,527,1],[526,2,527,2],[526,4,527,4],[526,5,527,5],[526,6,527,6],[526,7,527,7],[526,8,527,8],[526,9,527,9],[526,10,527,10],[526,11,527,11],[526,12,527,12],[526,13,527,13],[528,1,529,1],[528,2,529,2],[528,4,529,4],[528,5,529,5],[528,6,529,6],[528,7,529,7],[528,8,529,8],[528,9,529,9],[528,10,529,10],[528,11,529,11],[528,12,529,12],[528,13,529,13],[530,1,531,1],[530,2,531,2],[530,3,531,3],[530,4,531,4],[530,5,531,5],[530,6,531,6],[530,7,531,7],[530,8,531,8],[530,9,531,9],[530,10,531,10],[530,11,531,11],[530,12,531,12],[530,13,531,13],[532,1,533,1],[532,2,533,2],[532,3,533,3],[532,4,533,4],[532,5,533,5],[532,6,533,6],[532,7,533,7],[532,8,533,8],[532,9,533,9],[532,10,533,10],[532,11,533,11],[532,12,533,12],[532,13,533,13],[534,1,535,1],[534,2,535,2],[534,3,535,3],[534,4,535,4],[534,5,535,5],[534,6,535,6],[534,7,535,7],[534,8,535,8],[534,9,535,9],[534,10,535,10],[534,11,535,11],[534,12,535,12],[534,13,535,13]]}
[{"$nulls":3},"Neuronal Signaling Compound Library  (96-well)-L4000"]
[null,"For more information on Selleck library service, please contact us via +1-832-582-8158 or library@selleckchem.com"]
[]
[null,"Product Details:"]
[null,"Description",null,"A unique collection of 1737 compounds"]
[null,"Container",null,"96  Well"]
[null,"Stability",null,"12 months | ﹣20°C | in DMSO"]
[{"$nulls":3},"24 months | ﹣80°C | in DMSO"]
[null,"Shipping",null,"Blue ice or Dry ice"]
[null,"Formulation",null,"Solubility ≥10 mM pre-dissolved in 10 mM solution and solubility between 2 mM and 10 mM pre-dissolved in 2 mM solution"]
[{"$nulls":3},"In 10 mM DMSO : Plate layout L4000-01~21;    In 2 mM DMSO : Plate layout L4000-24"]
[{"$nulls":3},"In 10 mM Water: Plate layout L4000-22~23;      In 2 mM Water  : Plate layout L4000-25"]
[]
[]
[null,"Plate layout: L4000-01"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1006","S1129","S1243","S1280","S1324","S1343","S1385","S1405","S1438","S1481","Empty"]
[{"$nulls":3},"Saracatinib (AZD0530)","SRT1720 HCl","Agomelatine (S20098)","Amisulpride","Doxazosin Mesylate","Ginkgolide B","Mosapride Citrate","Vecuronium Bromide","Topiramate","Zosuquidar (LY335979) 3HCl"]
[null,"b","Empty","S1039","S1152","S1245","S1281","S1326","S1351","S1387","S1407","S1441","S1483","Empty"]
[{"$nulls":3},"Rapamycin (AY-22989)","PLX-4720","Latrepirdine 2HCl","Aniracetam","Edaravone","Ivermectin (MK-933)","Naftopidil DiHCl","Bimatoprost","Venlafaxine HCl","Iloperidone"]
[null,"c","Empty","S1064","S1168","S1255","S1283","S1328","S1356","S1390","S1409","S1444","S1488","Empty"]
[{"$nulls":3},"Masitinib (AB1010)","Valproic Acid (NSC 93819) sodium salt","Nepafenac","Asenapine maleate","Etodolac","Levetiracetam (UCB-L059)","Ondansetron HCl","Alfuzosin HCl","Ziprasidone HCl","Naratriptan HCl"]
[null,"d","Empty","S1066","S1189","S1256","S1286","S1330","S1357","S1391","S1415","S1445","S1500","Empty"]
[{"$nulls":3},"SL-327","Aprepitant (MK-0869)","Rufinamide","Budesonide","Felbamate","Lidocaine","Oxcarbazepine","Clopidogrel (SR-25990C) Bisulfate","Zonisamide","Betamethasone"]
[null,"e","Empty","S1075","S1193","S1258","S1290","S1332","S1358","S1394","S1425","S1455","S1504","Empty"]
[{"$nulls":3},"SB216763","Thalidomide (K17)","Prasugrel","Celastrol (NSC 70931)","Flumazenil (RO 15-1788)","Loratadine (SCH29851)","Pizotifen Malate","Ranolazine 2HCl","Cilomilast","Dyphylline"]
[null,"f","Empty","S1107","S1201","S1259","S1291","S1333","S1359","S1396","S1432","S1458","S1508","Empty"]
[{"$nulls":3},"Danusertib (PHA-739358)","Dimesna","Ramelteon","Cetirizine DiHCl","Fluoxetine (Lilly 110140) HCl","Losartan Potassium (DuP 753)","Resveratrol (SRT501)","Sumatriptan Succinate","Neflamapimod (VX-745)","Alprostadil"]
[null,"g","Empty","S1120","S1204","S1261","S1293","S1334","S1379","S1397","S1435","S1460","S1512","Empty"]
[{"$nulls":3},"Everolimus (RAD001)","Melatonin (NSC 113928)","Celecoxib (SC 58635)","Cilnidipine (FRC-8653)","Flupirtine maleate","Isotretinoin","Rocuronium Bromide","Tamsulosin hydrochloride","SP600125","Tadalafil (IC351)"]
[null,"h","Empty","S1124","S1206","S1262","S1315","S1336","S1382","S1404","S1437","S1472","S1528","Empty"]
[{"$nulls":3},"BMS-754807","Bisoprolol fumarate","Avagacestat (BMS-708163)","Ki16425","Fluvoxamine (DU-23000) maleate","Mianserin HCl","Trilostane","Tizanidine HCl","Safinamide Mesylate","LY2811376"]
[]
[]
[]
[null,"Plate layout: L4000-02"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1534","S1578","S1613","S1646","S1683","S1703","S1738","S1789","S1816","S1856","Empty"]
[{"$nulls":3},"Org 27569","Candesartan (CV-11974)","Silodosin","Ketorolac","Ipratropium Bromide","Divalproex Sodium","Telmisartan","Tetrabenazine (Xenazine)","Chlorpheniramine Maleate","Metoprolol Tartrate"]
[null,"b","Empty","S1541","S1590","S1614","S1647","S1688","S1709","S1747","S1792","S1827","S1865","Empty"]
[{"$nulls":3},"Selisistat (EX 527)","TWS119","Riluzole (PK 26124)","Adenosine","Betamethasone Dipropionate","Estradiol","Nimodipine","Simvastatin (MK 733)","Betaxolol HCl","Diltiazem HCl"]
[null,"c","Empty","S1544","S1594","S1619","S1649","S1689","S1713","S1748","S1799","S1828","S1866","Empty"]
[{"$nulls":3},"AM1241","Semagacestat (LY450139)","Prilocaine","Zolmitriptan","Meprednisone","Piroxicam","Nisoldipine","Ranolazine","Proparacaine HCl","Diphenhydramine HCl"]
[null,"d","Empty","S1545","S1601","S1622","S1654","S1690","S1723","S1754","S1801","S1831","S1869","Empty"]
[{"$nulls":3},"SB408124","Reserpine","Prednisone (NSC-10023)","Phenylbutazone","Betamethasone Valerate","Indomethacin (NSC-77541)","Oxybutynin","Ranitidine Hydrochloride","Carvedilol","Dapoxetine HCl"]
[null,"e","Empty","S1549","S1603","S1626","S1662","S1693","S1733","S1759","S1805","S1832","S1880","Empty"]
[{"$nulls":3},"Nebivolol hydrochloride (R-65824)","Furosemide (NSC 269420)","Naproxen Sodium","Isradipine","Carbamazepine","Methylprednisolone (NSC-19987)","Pitavastatin (NK-104) calcium","Acetylcholine Chloride","Atracurium Besylate","Roxatidine Acetate HCl"]
[null,"f","Empty","S1550","S1604","S1628","S1669","S1696","S1734","S1761","S1808","S1845","S1885","Empty"]
[{"$nulls":3},"Pimobendan","Olmesartan Medoxomil","Triamcinolone Acetonide","Loteprednol etabonate","Hydrocortisone (NSC 10483)","Meloxicam","Suprofen","Nifedipine (BAY-a-1040)","Cimetidine","Felodipine"]
[null,"g","Empty","S1573","S1607","S1638","S1673","S1701","S1736","S1763","S1811","S1847","S1888","Empty"]
[{"$nulls":3},"Fasudil (HA-1077) HCl","Rizatriptan Benzoate","Ibuprofen (NSC 256857)","Aminophylline","Desonide","Methocarbamol","Quetiapine (ICI-204636) fumarate","Amiloride (MK-870) HCl","Clemastine (HS-592) fumarate","Deflazacort"]
[null,"h","Empty","S1576","S1608","S1645","S1679","S1702","S1737","S1771","S1813","S1848","S1890","Empty"]
[{"$nulls":3},"Sulfasalazine (NSC 667219)","Pyridostigmine Bromide","Ketoprofen","Flurbiprofen","Didanosine","Prednisolone (NSC-9900)","Chlorprothixene","Amlodipine Besylate","Curcumin","Nizatidine"]
[]
[]
[]
[null,"Plate layout: L4000-03"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1891","S1920","S1975","S2016","S2030","S2046","S2075","S2086","S2103","S2130","Empty"]
[{"$nulls":3},"Carbidopa","Haloperidol","Aripiprazole","Mirtazapine","Flunarizine 2HCl","Pioglitazone HCl","Rosiglitazone (BRL-49653) HCl","Ivabradine HCl","Naltrexone HCl","Atropine sulfate monohydrate"]
[null,"b","Empty","S1894","S1928","S1978","S2017","S2032","S2054","S2077","S2087","S2104","S2131","Empty"]
[{"$nulls":3},"Valsartan (CGP-48933)","Alibendol","Methscopolamine","Benidipine HCl","Rebamipide","Orphenadrine Citrate","Atorvastatin Calcium","Rivastigmine Tartrate","Levosulpiride","Roflumilast (B9302-107)"]
[null,"c","Empty","S1898","S1933","S1987","S2020","S2037","S2059","S2078","S2090","S2108","S2149","Empty"]
[{"$nulls":3},"Tropisetron HCl","Triamcinolone","Mometasone furoate","Formoterol Hemifumarate","Candesartan Cilexetil","Terazosin HCl Dihydrate","Famotidine","Dexmedetomidine HCl","Flunixin Meglumin","GSK1292263"]
[null,"d","Empty","S1899","S1952","S1990","S2021","S2038","S2061","S2080","S2091","S2113","S2153","Empty"]
[{"$nulls":3},"Nicotinamide (NSC 13128)","Methoxsalen","Capsaicin(Vanilloid)","Chlormezanone","Phentolamine Mesylate","Lovastatin (MK-803)","Clevidipine Butyrate","Betaxolol","Cisatracurium Besylate","CGS 21680 HCl"]
[null,"e","Empty","S1903","S1959","S1992","S2024","S2040","S2065","S2082","S2092","S2114","S2156","Empty"]
[{"$nulls":3},"Diclofenac Sodium","Tolfenamic Acid","Fluticasone propionate","Ketotifen Fumarate","Nimesulide","Lafutidine","Adiphenine HCl","Detomidine HCl","Dronedarone HCl","LY2886721"]
[null,"f","Empty","S1905","S1960","S1994","S2025","S2041","S2066","S2083","S2096","S2118","S2160","Empty"]
[{"$nulls":3},"Amlodipine","Pranoprofen","Lacidipine","Urapidil HCl","Dyclonine HCl","Moxonidine","Procaterol HCl","Almotriptan Malate","Ibutilide Fumarate","Almorexant HCl"]
[null,"g","Empty","S1913","S1965","S2007","S2026","S2043","S2067","S2084","S2098","S2126","S2168","Empty"]
[{"$nulls":3},"Tropicamide","Primidone","Sulindac","Ginkgolide A","Memantine HCl","Ozagrel HCl","Duloxetine HCl","Bexarotene (LGD1069)","Naftopidil","PD128907 HCl"]
[null,"h","Empty","S1914","S1969","S2011","S2029","S2044","S2072","S2085","S2102","S2127","S2215","Empty"]
[{"$nulls":3},"Pregnenolone","Nefiracetam","Pramipexole 2HCl Monohydrate","Uridine","Cyproheptadine HCl","Seratrodast(AA-2414)","Trimebutine","Rasagiline Mesylate","S-(+)-Rolipram","DAPT (GSI-IX)"]
[]
[]
[]
[null,"Plate layout: L4000-04"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S2228","S2304","S2339","S2373","S2403","S2452","S2466","S2494","S2508","S2525","Empty"]
[{"$nulls":3},"Belnacasan (VX-765)","Gramine","Paeonol","Yohimbine HCl","Tetrandrine (NSC-77037)","Amfebutamone (Bupropion) HCl","Estriol","Olopatadine HCl","Scopolamine (LSM-4015) HBr","Phenytoin"]
[null,"b","Empty","S2261","S2308","S2346","S2374","S2410","S2454","S2470","S2496","S2509","S2529","Empty"]
[{"$nulls":3},"Andrographolide","Hesperetin","Puerarin","5-hydroxytryptophan (5-HTP)","Paeoniflorin (NSC 178886)","Bupivacaine HCl","Fluocinolone Acetonide","Ozagrel","Sotalol HCl","Dopamine HCl"]
[null,"c","Empty","S2269","S2312","S2347","S2377","S2411","S2455","S2471","S2497","S2512","S2531","Empty"]
[{"$nulls":3},"Baicalin (NSC-661431)","Icariin","Quercetin Dihydrate","Biochanin A","Geniposide","Bethanechol chloride","Gallamine Triethiodide","Pancuronium dibromide","Tenoxicam","Asaraldehyde"]
[null,"d","Empty","S2276","S2314","S2349","S2378","S2415","S2456","S2480","S2499","S2516","S2533","Empty"]
[{"$nulls":3},"Bilobalide","Kaempferol (NSC 407289)","Rutaecarpine","Butylscopolamine Bromide","Astragaloside A","Chlorpromazine HCl","Loperamide HCl","Phenoxybenzamine HCl","Xylazine HCl","Ritodrine HCl"]
[null,"e","Empty","S2277","S2318","S2351","S2383","S2437","S2458","S2481","S2500","S2517","S2535","Empty"]
[{"$nulls":3},"Caffeic Acid","Lappaconitine","Salicin","Gastrodin","Rotundine","Clonidine HCl","Manidipine","Propafenone HCl","Maprotiline HCl","Econazole nitrate"]
[null,"f","Empty","S2282","S2322","S2359","S2396","S2438","S2459","S2482","S2502","S2519","S2541","Empty"]
[{"$nulls":3},"Cinchonidine","(+)-Matrine","Sinomenine","Salidroside","Synephrine HCl","Clozapine","Manidipine 2HCl","Quinine HCl Dihydrate","Naphazoline HCl","Clomipramine HCl"]
[null,"g","Empty","S2287","S2331","S2362","S2397","S2446","S2460","S2491","S2503","S2521","S2545","Empty"]
[{"$nulls":3},"Cytisine","Neohesperidin Dihydrochalcone (Nhdc)","Synephrine","Palmatine chloride","Levosimendan","Pramipexole","Nitrendipine","Racecadotril","Epinephrine bitartrate","Scopine"]
[null,"h","Empty","S2302","S2337","S2363","S2399","S2451","S2461","S2493","S2505","S2524","S2547","Empty"]
[{"$nulls":3},"Glycyrrhizin (NSC 167409)","Osthole","Tangeretin","Dihydromyricetin","Amantadine HCl","Domperidone","Olanzapine","Rosiglitazone (BRL-49653) maleate","Phenytoin Sodium","Tiotropium Bromide hydrate"]
[]
[]
[]
[null,"Plate layout: L4000-05"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S2549","S2573","S2603","S2631","S2695","S2785","S2828","S2861","S2892","S3005","Empty"]
[{"$nulls":3},"Trospium chloride","Tetracaine HCl","Tioxolone","URB597","Nepicastat (SYN-117) HCl","A-803467","JNJ-1661010","CTEP (RO4956371)","VU 0361737","Paroxetine HCl"]
[null,"b","Empty","S2552","S2576","S2605","S2660","S2698","S2790","S2849","S2862","S2894","S3008","Empty"]
[{"$nulls":3},"Azelastine HCl","Xylometazoline HCl","Idebenone","MK-0752","RS-127445","Istradefylline","SB269970 HCl","VU 0364770","SB742457","Zaltoprofen"]
[null,"c","Empty","S2556","S2577","S2606","S2663","S2711","S2795","S2852","S2865","S2903","S3017","Empty"]
[{"$nulls":3},"Rosiglitazone (BRL 49653)","Phenacetin","Mifepristone (RU486)","WAY-100635 Maleate","Dibenzazepine (YO-01027)","VU 0357121","BRL-54443","VUF 10166","Lumiracoxib","Aspirin (NSC 27223)"]
[null,"d","Empty","S2559","S2584","S2607","S2666","S2714","S2809","S2854","S2866","S2905","S3018","Empty"]
[{"$nulls":3},"Cortisone acetate","Clobetasol propionate","Buflomedil HCl","PF-3845","LY411575","MPEP","BML-190","U-104","JNJ-7777120","Niflumic acid"]
[null,"e","Empty","S2566","S2585","S2608","S2677","S2721","S2813","S2855","S2874","S2910","S3021","Empty"]
[{"$nulls":3},"Isoprenaline (NCI-C55630) HCl","Brompheniramine hydrogen maleate","Fluocinonide","BRL-15572 Dihydrochloride","Nilvadipine","Ciproxifan Maleate","MRS 2578","Camostat Mesilate","Tempol","Rimonabant (SR141716)"]
[null,"f","Empty","S2567","S2590","S2614","S2687","S2722","S2816","S2856","S2875","S2918","S3023","Empty"]
[{"$nulls":3},"Medroxyprogesterone acetate (NSC-26386)","Pioglitazone (AD-4833)","Arecoline HBr","Mardepodect (PF-2545920)","JTC-801","Tyrphostin AG 879","SB 271046 hydrochloride","Prucalopride","HC-030031","Bufexamac"]
[null,"g","Empty","S2569","S2594","S2615","S2690","S2773","S2819","S2857","S2876","S2929","S3024","Empty"]
[{"$nulls":3},"Phenylephrine (NCI-C55641) HCl","Pramiracetam","Noradrenaline bitartrate monohydrate","ADX-47273","SB705498","AM251","(-)-Dizocilpine (MK 801) Maleate","(+)-Dizocilpine (MK 801) Maleate","Pifithrin-α (PFTα) HBr","Lamotrigine"]
[null,"h","Empty","S2570","S2602","S2629","S2691","S2778","S2823","S2860","S2891","S3003","S3025","Empty"]
[{"$nulls":3},"Prednisolone Acetate","Acemetacin","PNU-120596","BMY 7378 Dihydrochloride","GW842166X","Tideglusib (NP031112)","IEM 1754 2HBr","GW441756","Prostaglandin E2 (PGE2)","PMSF"]
[]
[]
[]
[null,"Plate layout: L4000-06"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S3037","S3054","S3078","S3150","S3180","S3201","S3622","S3643","S3682","S3706","Empty"]
[{"$nulls":3},"Bepotastine Besilate","Alverine Citrate","Beclomethasone dipropionate","Articaine HCl","Eletriptan HBr","Trifluoperazine 2HCl","Diammonium Glycyrrhizinate","Amitraz","Ethyl 3-Aminobenzoate methanesulfonate","Sarpogrelate hydrochloride"]
[null,"b","Empty","S3038","S3057","S3083","S3153","S3183","S3208","S3624","S3647","S3684","S3716","Empty"]
[{"$nulls":3},"Fosaprepitant dimeglumine salt","Azilsartan Medoxomil","Indacaterol Maleate","Levalbuterol tartrate","Amitriptyline HCl","Fexofenadine HCl","Quinolinic acid","Mafenide Acetate","Methacholine chloride","Flibanserin"]
[null,"c","Empty","S3043","S3060","S3100","S3155","S3185","S3212","S3625","S3653","S3690","S3723","Empty"]
[{"$nulls":3},"Rofecoxib","Medetomidine HCl","2-Thiouracil","Mepivacaine HCl","Adrenalone HCl","Moclobemide (Ro 111163)","Tyramine","Spermidine trihydrochloride","Pargyline hydrochloride","Ramosetron Hydrochloride"]
[null,"d","Empty","S3045","S3061","S3117","S3163","S3186","S3600","S3627","S3654","S3697","S3726","Empty"]
[{"$nulls":3},"Cinepazide maleate","Epinephrine HCl","Oxybutynin hydrochloride","Benztropine mesylate","Azatadine dimaleate","Schisandrin B (Sch B)","Tryptamine","Tauroursodeoxycholic Acid (TUDCA)","Mafenide hydrochloride","Selexipag"]
[null,"e","Empty","S3046","S3063","S3120","S3173","S3189","S3611","S3629","S3656","S3698","S3727","Empty"]
[{"$nulls":3},"Azilsartan","Diclofenac Diethylamine","Doxepin HCl","Antipyrine","Ropinirole HCl","(+)-Fangchinoline","Syringic acid","Piribedil","Nortriptyline hydrochloride","Vilanterol Trifenate"]
[null,"f","Empty","S3047","S3066","S3140","S3175","S3196","S3612","S3634","S3663","S3700","S3735","Empty"]
[{"$nulls":3},"Otilonium Bromide","Naloxone HCl","Milnacipran HCl","Atomoxetine HCl","Azacyclonol","Rosmarinic acid","6-Hydroxyflavone (6-HF)","Afloqualone","DHBP dibromide","Umeclidinium bromide"]
[null,"g","Empty","S3052","S3070","S3144","S3176","S3199","S3616","S3639","S3665","S3701","S3738","Empty"]
[{"$nulls":3},"Rupatadine Fumarate","Piracetam","Darifenacin HBr","Betahistine 2HCl","Reboxetine mesylate","Asiaticoside","Tacrine hydrochloride hydrate","Trolox","Benactyzine hydrochloride","Travoprost"]
[null,"h","Empty","S3053","S3071","S3147","S3178","S3200","S3617","S3640","S3674","S3704","S3751","Empty"]
[{"$nulls":3},"Azelnidipine","Vanillin","Entacapone","Brinzolamide","Triflusal","(20S)-Protopanaxatriol","Methoxyphenamine Hydrochloride","Levamlodipine","4-Methylbenzylidene camphor","Quinidine hemisulfate hydrate"]
[]
[]
[]
[null,"Plate layout: L4000-07"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S3756","S3785","S3811","S3835","S3865","S3883","S3903","S3931","S3969","S4009","Empty"]
[{"$nulls":3},"Methyl salicylate","Notoginsenoside R1","Ginsenoside Re","Loganin","Taurochenodeoxycholic acid","Protopine","Lycorine","Ginsenoside Rd","Veratric acid","Mirabegron"]
[null,"b","Empty","S3758","S3786","S3816","S3841","S3866","S3884","S3904","S3935","S3974","S4010","Empty"]
[{"$nulls":3},"Sinomenine hydrochloride","Glabridin","Dehydroevodiamine","Eleutheroside B","Galanthamine","Jatrorrhizine","Isoimperatorin","Nonivamide","(+)-Catechin hydrate","Acebutolol HCl"]
[null,"c","Empty","S3763","S3788","S3817","S3844","S3867","S3886","S3907","S3942","S3977","S4011","Empty"]
[{"$nulls":3},"Cinnamaldehyde","Carvacrol","Harmine hydrochloride","Rosavin","(E)-Cardamonin","Quinic acid","Bulleyaconi cine A","Cardamonin","(-)-Borneol","Ampiroxicam"]
[null,"d","Empty","S3764","S3791","S3820","S3851","S3868","S3894","S3909","S3944","S3988","S4012","Empty"]
[{"$nulls":3},"Isoferulic Acid","Succinic acid","Dehydroevodiamine hydrochloride","Camphor","Harmine","Cycloastragenol","Catalpol","Valproic acid (VPA)","Theophylline-7-acetic acid","Desloratadine"]
[null,"e","Empty","S3766","S3797","S3823","S3854","S3872","S3895","S3911","S3945","S3990","S4014","Empty"]
[{"$nulls":3},"Tanshinone IIA sulfonate sodium","Helicide","Schizandrol A","Tetrahydropalmatine hydrochloride","Guaiacol","Sophoridine","Veratramine","L-Cycloserine","Trans-Anethole","Hyoscyamine"]
[null,"f","Empty","S3769","S3800","S3828","S3855","S3874","S3899","S3923","S3959","S3992","S4021","Empty"]
[{"$nulls":3},"Palmatine","Lycorine hydrochloride","Orcinol glucoside","Ethyl ferulate","Curcumenol","Hederagenin","Ginsenoside Rg1","(+)-Borneol","D-(+)-Trehalose dihydrate","Tolcapone"]
[null,"g","Empty","S3781","S3802","S3833","S3856","S3880","S3901","S3924","S3960","S3996","S4022","Empty"]
[{"$nulls":3},"Ginkgolide C","Trigonelline Hydrochloride","Amentoflavone","Allantoin","Schisantherin A","Astragaloside IV","Ginsenoside Rb1","Higenamine hydrochloride","Thioctic acid","Probenecid"]
[null,"h","Empty","S3783","S3809","S3834","S3857","S3881","S3902","S3925","S3968","S4000","S4023","Empty"]
[{"$nulls":3},"Echinacoside","Imperatorin","Astaxanthin","4-Hydroxybenzyl alcohol","Scopoletin","Ursonic acid","(-)-Epicatechin gallate","Histamine","Pergolide Mesylate","Procaine HCl"]
[]
[]
[]
[null,"Plate layout: L4000-08"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4024","S4043","S4065","S4086","S4112","S4135","S4164","S4202","S4233","S4249","Empty"]
[{"$nulls":3},"Homatropine Methylbromide","Tetrahydrozoline HCl","Guanabenz Acetate","Loxapine Succinate","Desvenlafaxine Succinate hydrate","Clorprenaline HCl","Doxofylline","Verapamil (CP-16533-1) HCl","Zoxazolamine","Flopropione"]
[null,"b","Empty","S4025","S4045","S4072","S4088","S4113","S4136","S4170","S4210","S4235","S4251","Empty"]
[{"$nulls":3},"Homatropine Bromide","Pheniramine Maleate","Decamethonium Bromide","Flumethasone","Desvenlafaxine","Carprofen","Coumarin","Benzocaine","Phenazopyridine HCl","Phenothiazine"]
[null,"c","Empty","S4026","S4049","S4076","S4090","S4116","S4139","S4171","S4219","S4240","S4253","Empty"]
[{"$nulls":3},"Hydroxyzine 2HCl","Valdecoxib","Propranolol HCl","Fenspiride HCl","Isovaleramide","Cyclizine 2HCl","Choline Chloride","Azaperone","Doxylamine Succinate","Epinastine HCl"]
[null,"d","Empty","S4031","S4051","S4078","S4091","S4118","S4143","S4176","S4225","S4243","S4256","Empty"]
[{"$nulls":3},"Aclidinium Bromide","Nabumetone","Mefenamic Acid","Ifenprodil Tartrate","Histamine 2HCl","Pentoxyverine Citrate","Trometamol","Mexiletine HCl","Deoxycorticosterone acetate","Buspirone HCl"]
[null,"e","Empty","S4034","S4053","S4079","S4092","S4123","S4149","S4181","S4228","S4244","S4257","Empty"]
[{"$nulls":3},"Diphemanil Methylsulfate","Sertraline HCl","Ticagrelor","Pramoxine HCl","Timolol Maleate","Amfenac Sodium Monohydrate","Nicardipine HCl","Fluorometholone Acetate","Serotonin HCl","Alizapride HCl"]
[null,"f","Empty","S4037","S4058","S4080","S4096","S4124","S4151","S4188","S4229","S4246","S4259","Empty"]
[{"$nulls":3},"Doxapram HCl","Ropivacaine HCl","Triamterene","Droperidol","Tolazoline HCl","Penfluridol","Sasapyrine","Oxybuprocaine HCl","Tranylcypromine (2-PCPA) HCl","Vilazodone HCl"]
[null,"g","Empty","S4038","S4061","S4084","S4100","S4125","S4155","S4197","S4230","S4247","S4261","Empty"]
[{"$nulls":3},"Dibucaine HCl","Levobupivacaine HCl","Lomerizine 2HCl","Esmolol HCl","Sodium Phenylbutyrate","Chlorzoxazone","Bemegride","Oxaprozin","Prucalopride Succinate","EUK 134"]
[null,"h","Empty","S4039","S4064","S4085","S4102","S4131","S4162","S4200","S4231","S4248","S4265","Empty"]
[{"$nulls":3},"Methazolamide","Escitalopram Oxalate","Levobetaxolol HCl","Eprosartan Mesylate","Levodropropizine","Benzethonium Chloride","Tolperisone HCl","Pilocarpine HCl","Bromfenac Sodium","Nicaraven"]
[]
[]
[]
[null,"Plate layout: L4000-09"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4266","S4283","S4296","S4334","S4353","S4382","S4506","S4535","S4587","S4625","Empty"]
[{"$nulls":3},"Brimonidine Tartrate","Cyclobenzaprine HCl","Salmeterol Xinafoate","Mesoridazine Besylate","Terfenadine","Pyrilamine Maleate","Acetazolamide","Methylene Blue","Pentylenetetrazol","Alcaftadine"]
[null,"b","Empty","S4268","S4284","S4301","S4335","S4357","S4389","S4508","S4539","S4588","S4626","Empty"]
[{"$nulls":3},"Flufenamic acid","Chloroprocaine HCl","(R)-(+)-Atenolol HCl","Metaproterenol Sulfate","Tacrine HCl","Bephenium Hydroxynaphthoate","2,2,2-Tribromoethanol","Salicylic acid","Docusate Sodium","Ethosuximide"]
[null,"c","Empty","S4270","S4289","S4305","S4336","S4358","S4391","S4509","S4542","S4597","S4628","Empty"]
[{"$nulls":3},"Oxiracetam","Metoclopramide HCl","Anisotropine Methylbromide","Metaraminol Bitartrate","Pimozide","Camylofin Chlorhydrate","4-Aminoantipyrine","Trihexyphenidyl hydrochloride","Lercanidipine hydrochloride","(+/-)-Sulfinpyrazone"]
[null,"d","Empty","S4274","S4291","S4309","S4338","S4373","S4406","S4512","S4544","S4600","S4630","Empty"]
[{"$nulls":3},"Rotigotine","Labetalol HCl","Bromocriptine Mesylate","Methoxamine HCl","Dicyclomine HCl","Pindolol","Aceglutamide","Urethane","Benzyl alcohol","Diazoxide"]
[null,"e","Empty","S4277","S4292","S4317","S4342","S4376","S4409","S4516","S4569","S4609","S4631","Empty"]
[{"$nulls":3},"Bambuterol HCl","Diphenidol HCl","Clorgyline HCl","Nialamide","Aceclidine HCl","Quipazine Maleate","(+)-Camphor","Fluphenazine dihydrochloride","Diflunisal","Prochlorperazine dimaleate salt"]
[null,"f","Empty","S4278","S4293","S4319","S4343","S4377","S4416","S4520","S4570","S4618","S4635","Empty"]
[{"$nulls":3},"Carteolol HCl","Promethazine HCl","Dibenzepine HCl","Oxethazaine","Imipramine HCl","Trimipramine Maleate","2-Aminoheptane","Halothane","Fenoldopam mesylate","Cyproheptadine hydrochloride sesquihydrate"]
[null,"g","Empty","S4280","S4294","S4320","S4344","S4380","S4422","S4526","S4571","S4619","S4637","Empty"]
[{"$nulls":3},"Meclofenoxate (Centrophenoxine) HCl","Procainamide HCl","Dimaprit 2HCl","Oxprenolol HCl","Nomifensine Maleate","Nitenpyram","Fenbufen","Hexylresorcinol","Itopride hydrochloride","Prasugrel Hydrochloride"]
[null,"h","Empty","S4281","S4295","S4329","S4349","S4381","S4505","S4529","S4583","S4623","S4648","Empty"]
[{"$nulls":3},"Tasimelteon","Meclofenamate Sodium","Hemicholinium Bromide","Procyclidine HCl","Proadifen HCl","Vinblastine (NSC-49842) sulfate","Idramantone","Butamben","Methylbenactyzine Bromide","Dantrolene sodium hemiheptahydrate"]
[]
[]
[]
[null,"Plate layout: L4000-10"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4649","S4662","S4693","S4719","S4746","S4769","S4817","S4889","S4961","S4992","Empty"]
[{"$nulls":3},"Atipamezole hydrochloride","Atazanavir","Guanfacine Hydrochloride","Kynurenic acid","(20S)-Protopanaxadiol","L-5-Hydroxytryptophan","Atenolol","Perospirone hydrochloride","3,4,5-Trimethoxycinnamic acid","Nanofin"]
[null,"b","Empty","S4650","S4667","S4696","S4725","S4748","S4772","S4832","S4892","S4969","S4994","Empty"]
[{"$nulls":3},"Atipamezole","Lidocaine hydrochloride","CarbinoxaMine Maleate","Benzenesulfonamide","Ondansetron Hydrochloride Dihydrate","alpha-Asarone","Tolmetin","Phenibut","Tropine","Methylcobalamin"]
[null,"c","Empty","S4651","S4669","S4707","S4727","S4749","S4774","S4834","S4902","S4970","S5010","Empty"]
[{"$nulls":3},"Etoricoxib","Benzocaine hydrochloride","Oleic Acid","Cinnarizine","Citalopram HBr","Xanthurenic Acid","Propantheline bromide","QNZ (EVP4593)","Nerol","Indometacin Sodium"]
[null,"d","Empty","S4655","S4672","S4714","S4731","S4751","S4775","S4837","S4904","S4973","S5019","Empty"]
[{"$nulls":3},"Sulpiride","Dimenhydrinate","(-)-Menthol","Perphenazine","Cisapride hydrate","Cortodoxone","Ibudilast","JZL184","Iminostilbene","Indobufen"]
[null,"e","Empty","S4656","S4679","S4715","S4732","S4752","S4787","S4838","S4926","S4975","S5023","Empty"]
[{"$nulls":3},"Parecoxib","Terazosin HCl","Benzamide","MPTP hydrochloride","Corticosterone (NSC-9705)","Methyl syringate","Acotiamide hydrochloride","(R)-Nepicastat HCl","Fimasartan","Nadolol"]
[null,"f","Empty","S4657","S4682","S4716","S4733","S4760","S4797","S4839","S4931","S4977","S5032","Empty"]
[{"$nulls":3},"Eslicarbazepine Acetate","Loxoprofen","Evans Blue","Retigabine","(2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD)","Nicergoline","Mosapride","Propiverine hydrochloride","Efonidipine","Mephenesin"]
[null,"g","Empty","S4660","S4686","S4717","S4734","S4765","S4804","S4849","S4932","S4989","S5034","Empty"]
[{"$nulls":3},"Glycopyrrolate","Vitamin E","Isatin","Retigabine 2HCl","Syringaldehyde","1-Naphthyl acetate","Levocetirizine Dihydrochloride","Proxyphylline","AOA hemihydrochloride","Melitracen hydrochloride"]
[null,"h","Empty","S4661","S4687","S4718","S4739","S4767","S4809","S4856","S4957","S4991","S5038","Empty"]
[{"$nulls":3},"Tiagabine hydrochloride","Rivastigmine","Acetylcholine iodide","Oxyresveratrol","7-Hydroxy-3,4-dihydrocarbostyril","3-Indolepropionic acid","Iproniazid","Linalool","Valpromide","Valethamate Bromide"]
[]
[]
[]
[null,"Plate layout: L4000-11"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S5042","S5073","S5153","S5238","S5269","S5309","S5357","S5398","S5432","S5478","Empty"]
[{"$nulls":3},"Bevantolol hydrochloride","Donepezil","Tetrahydroberberine","Solifenacin (YM905)","J147","Propyphenazone (4-Isopropylantipyrine)","Safinamide","Nefazodone hydrochloride","Dibenamine Hydrochloride","Dantrolene sodium"]
[null,"b","Empty","S5045","S5075","S5154","S5239","S5274","S5319","S5358","S5399","S5444","S5479","Empty"]
[{"$nulls":3},"Nomilin","Acotiamide","Tetrahydropiperine","Paroxetine mesylate","GS967","Imepitoin","Regadenoson","Chlorprothixene hydrochloride","4-Bromo-3-hydroxybenzoic acid","Cloperastine hydrochloride"]
[null,"c","Empty","S5049","S5085","S5177","S5247","S5279","S5326","S5360","S5401","S5447","S5480","Empty"]
[{"$nulls":3},"Thiocolchicoside","Azamethiphos","Naproxen","Selamectin","Fendiline hydrochloride","Dolasetron","Diflorasone","Tegaserod Maleate","Triprolidine Hydrochloride","Clidinium Bromide"]
[null,"d","Empty","S5052","S5088","S5179","S5253","S5281","S5329","S5363","S5418","S5457","S5481","Empty"]
[{"$nulls":3},"Granisetron","Labetalone hydrochloride","Ropivacaine Mesilate","Cisapride (R 51619)","Dapiprazole Hydrochloride","FAAH-IN-2","Pikamilone","Parecoxib Sodium","Curculigoside","Molindone hydrochloride"]
[null,"e","Empty","S5060","S5100","S5203","S5255","S5286","S5337","S5366","S5419","S5464","S5482","Empty"]
[{"$nulls":3},"Metadoxine","Pralidoxime Iodide","Sulbutiamine","Nicardipine","Ramatroban","Rauwolscine hydrochloride","Fipronil","1,4-Cineole","Psoralidin","Prilocaine hydrochloride"]
[null,"f","Empty","S5066","S5101","S5217","S5257","S5302","S5341","S5371","S5424","S5466","S5483","Empty"]
[{"$nulls":3},"Pramipexole dihydrochloride","Tabersonine hydrochloride","Arformoterol Tartrate","Doxapram","6-Methoxy-2-naphthoic acid","Metroprolol succinate","Ajmaline","Carbaryl","Saikosaponin A","Tribenzagan Hydrochloride"]
[null,"g","Empty","S5067","S5110","S5222","S5258","S5303","S5346","S5385","S5428","S5472","S5485","Empty"]
[{"$nulls":3},"Losartan","Safflower Yellow","Coluracetam","Revefenacin","Afalanine (N-Acetyl-DL-phenylalanine)","2-Phenylethylamine hydrochloride","Imidafenacin","Promazine hydrochloride","Nafronyl oxalate salt","Desipramine Hydrochloride"]
[null,"h","Empty","S5071","S5141","S5224","S5266","S5305","S5347","S5392","S5430","S5476","S5486","Empty"]
[{"$nulls":3},"Duloxetine","Pyrithioxin","Adrafinil","Stiripentol","Bromisoval","2-Phenylethylamine","Mepivacaine","Metoprolol","Rolapitant","Fluorometholone"]
[]
[]
[]
[null,"Plate layout: L4000-12"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S5490","S5514","S5551","S5579","S5647","S5664","S5690","S5711","S5735","S5755","Empty"]
[{"$nulls":3},"Disopyramide","Lanthanum(III) chloride heptahydrate","6-Paradol","Chelidonic acid","Emedastine Difumarate","Orphenadrine Hydrochloride","Triacanthine","Deracoxib","Midodrine","Methyl Eugenol"]
[null,"b","Empty","S5493","S5520","S5556","S5595","S5649","S5665","S5693","S5714","S5739","S5766","Empty"]
[{"$nulls":3},"Atropine sulfate","Phenidone","(-)-Sparteine Sulfate","3-Carene","Hydroxyzine pamoate","Drofenine Hydrochloride","Levomilnacipran Hydrochloride","lurasidone","Nebivolol","Alfuzosin"]
[null,"c","Empty","S5494","S5527","S5559","S5596","S5654","S5666","S5698","S5715","S5740","S5768","Empty"]
[{"$nulls":3},"Salbutamol","Salmeterol","(+/-)-tetrahydropalmatine","(1S)-(-)-α-Pinene","Indacaterol","Moxisylyte hydrochloride","Ketorolac tromethamine salt","Atorvastatin","Palonosetron","Fenoterol hydrobromide"]
[null,"d","Empty","S5498","S5537","S5561","S5616","S5655","S5669","S5701","S5718","S5741","S5769","Empty"]
[{"$nulls":3},"Betahistine mesylate","Tizanidine","Ethacrynic Acid","4-Methylcatechol","Venlafaxine","Isoxsuprine hydrochloride","Alvimopan dihydrate (LY246736 dihydrate)","Acrivastine","Quetiapine","Fenoterol"]
[null,"e","Empty","S5501","S5538","S5563","S5619","S5656","S5670","S5703","S5723","S5742","S5778","Empty"]
[{"$nulls":3},"Hydrocortisone acetate","Tropisetron","Thioridazine hydrochloride","Betahistine","Diphenylpyraline hydrochloride","Chloropyramine hydrochloride","Carvedilol Phosphate","Carvedilol EP IMpurity E","Deferoxamine mesylate (Ba 33112)","Esmolol"]
[null,"f","Empty","S5504","S5540","S5564","S5620","S5659","S5673","S5705","S5725","S5747","S5780","Empty"]
[{"$nulls":3},"Ropivacaine","Landiolol hydrochloride","Xylazine","NSI-189","Emedastine","Mivacurium chloride","Raceanisodamine","Pempidine","Morantel tartrate","Prazosin"]
[null,"g","Empty","S5507","S5542","S5565","S5640","S5662","S5679","S5709","S5727","S5749","S5782","Empty"]
[{"$nulls":3},"Trimebutine maleate","7-Nitroindazole","Triflupromazine hydrochloride","Ethyl caffeate","Ranitidine","Dolasetron Mesylate","Norgestrel","Tetryzoline","Chlorpromazine","Doxazosin"]
[null,"h","Empty","S5511","S5547","S5567","S5642","S5663","S5683","S5710","S5734","S5750","S5783","Empty"]
[{"$nulls":3},"Ethyl (triphenylphosphoranylidene) acetate","Hydroxylammonium chloride","Trimethadione","Homovanillic acid","Minaprine dihydrochloride","Isoproterenol sulfate dihydrate","Ambroxol","Midodrine hydrochloride","DL-Norepinephrine hydrochloride","Montelukast"]
[]
[]
[]
[null,"Plate layout: L4000-13"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S5787","S5821","S5861","S5923","S5950","S6172","S6415","S6462","S6507","S7072","Empty"]
[{"$nulls":3},"Dronedarone","Linoleic acid","Lercanidipine","Celiprolol hydrochloride","Fingolimod","Brucine sulfate heptahydrate","Azeliragon (TTP488)","Amezinium (methylsulfate)","KN-92 phosphate","NMDA (N-Methyl-D-aspartic acid)"]
[null,"b","Empty","S5795","S5829","S5862","S5925","S6002","S6221","S6416","S6469","S6561","S7076","Empty"]
[{"$nulls":3},"Rasagiline","Monomyristin","Metoclopramide","Olodaterol hydrochloride","Disufenton sodium","Methyl cinnamate","JNJ 31020028","Thonzylamine","4-IBP","T0901317"]
[null,"c","Empty","S5796","S5836","S5868","S5926","S6008","S6228","S6422","S6470","S6569","S7098","Empty"]
[{"$nulls":3},"Vanoxerine dihydrochloride","IBMX","DL-Menthol","Pitolisant hydrochloride","p-Hydroxybenzaldehyde","Indole-2-carboxylic acid","Lazabemide","Fluralaner","VUF10460","PD123319"]
[null,"d","Empty","S5802","S5842","S5873","S5930","S6058","S6324","S6432","S6473","S6590","S7115","Empty"]
[{"$nulls":3},"Alprenolol hydrochloride","Cabergoline","Scopolamine HBr trihydrate","PNU 282987 HCl","β-Caryophyllene","5-Methoxytryptamine","Cevimeline HCl hemihydrate","Pinaverium bromide","Hydrocortisone butyrate","AMG-517"]
[null,"e","Empty","S5803","S5843","S5886","S5931","S6073","S6407","S6435","S6478","S6609","S7124","Empty"]
[{"$nulls":3},"Alrestatin","Cinitapride Hydrogen Tartrate","Hodostin","BQCA","Diclofenac acid","Tulobuterol hydrochloride","Mequitazine","Fipexide hydrochloride","JZL195","SC144"]
[null,"f","Empty","S5804","S5848","S5900","S5932","S6083","S6409","S6447","S6479","S6611","S7145","Empty"]
[{"$nulls":3},"N-Acetylcysteine amide","Frovatriptan Succinate","Edrophonium chloride","BIA 10-2474","DL-Dopa","Zucapsaicin","Carazolol","Isohomovanillic acid","Cyclothiazide","AZD1080"]
[null,"g","Empty","S5805","S5857","S5914","S5935","S6094","S6410","S6455","S6487","S6612","S7152","Empty"]
[{"$nulls":3},"Allopregnanolone","Trazodone","AK 7","Alvimopan","Imidazole-4(5)-acetic Acid Hydrochloride","Clemizole","Clebopride malate","fluticasone furoate","Betazole Dihydrochloride","C646"]
[null,"h","Empty","S5814","S5858","S5921","S5940","S6122","S6412","S6457","S6503","S7071","S7162","Empty"]
[{"$nulls":3},"cariporide","Vilazodone","Cyclopentolate Hydrochloride","Bepotastine","Cyclohexanecarboxamide","Altiratinib","Flurbiprofen Axetil","LX2343","(+)-Bicuculline","Mdivi-1"]
[]
[]
[]
[null,"Plate layout: L4000-14"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S7169","S7351","S7423","S7588","S7782","S7974","S8020","S8137","S8219","S8348","Empty"]
[{"$nulls":3},"Crenigacestat (LY3039478)","JSH-23","KN-93 Phosphate","Reversine","Dasatinib Monohydrate","L755507","GW0742","Capsazepine","Bitopertin","BMS-935177"]
[null,"b","Empty","S7188","S7366","S7435","S7673","S7818","S7993","S8025","S8172","S8238","S8367","Empty"]
[{"$nulls":3},"CID755673","LY2119620","AR-A014418","L-685,458","Pexidartinib (PLX3397)","SKF38393 HCl","GSK3787","Ro 61-8048","SB366791","GSK2193874"]
[null,"c","Empty","S7193","S7392","S7436","S7705","S7858","S7995","S8028","S8173","S8270","S8380","Empty"]
[{"$nulls":3},"1-Azakenpaullone","Loxistatin Acid (E-64C)","NH125","A-438079 HCl","Dibutyryl-cAMP (Bucladesine)","Ripasudil (K-115) hydrochloride dihydrate","Tariquidar (XR9576)","Verubecestat (MK-8931) Trifluoroacetate","SRT2183","YM-58483 (BTP2)"]
[null,"d","Empty","S7237","S7393","S7437","S7730","S7889","S7998","S8035","S8180","S8280","S8407","Empty"]
[{"$nulls":3},"OG-L002","Aloxistatin (E64d)","Sal003","NU1025","Xanthohumol","Entrectinib (RXDX-101)","VU 0364439","PF-CBP1 HCl","IMR-1","PF-06273340"]
[null,"e","Empty","S7253","S7396","S7445","S7731","S7914","S7999","S8073","S8183","S8291","S8409","Empty"]
[{"$nulls":3},"AZD2858","Calpeptin","APX-3330","AZD3839","Isoxazole 9 (ISX-9)","SKF96365","Optovin","Pimavanserin tartrate","Atractylenolide I","KG-501 (2-naphthol-AS-E-phosphate)"]
[null,"f","Empty","S7292","S7399","S7482","S7745","S7924","S8001","S8097","S8185","S8301","S8433","Empty"]
[{"$nulls":3},"RG2833 (RGFP109)","FLI-06","EHT 1864 2HCl","ANA-12","Bay K 8644","Ricolinostat (ACY-1215)","C-DIM12","FPS-ZM1","Ossirene","NS-398 (NS398)"]
[null,"g","Empty","S7295","S7420","S7519","S7762","S7960","S8010","S8104","S8192","S8314","S8447","Empty"]
[{"$nulls":3},"Apabetalone (RVX-208)","CA-074 methyl ester (CA-074 Me)","GNF-5837","TRx0237 (LMTX) mesylate","Larotrectinib (LOXO-101) sulfate","PRX-08066 Maleic acid","SCH58261","SUN11602","5-Iodotubercidin","8-OH-DPAT (8-Hydroxy-DPAT)"]
[null,"h","Empty","S7323","S7422","S7585","S7772","S7968","S8018","S8105","S8193","S8319","S8459","Empty"]
[{"$nulls":3},"Itanapraced (CHF 5074)","KN-62","SB-334867","Elacridar (GF120918)","P7C3","Nirogacestat (PF-03084014)","ZM241385","Lanabecestat (AZD3293)","7,8-Dihydroxyflavone","TAK-063"]
[]
[]
[]
[null,"Plate layout: L4000-15"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S8511","S8639","S9022","S9069","S9100","S9136","S9173","S9219","S9258","S9312","Empty"]
[{"$nulls":3},"Belizatinib (TSR-011)","Diphenyleneiodonium chloride (DPI)","20S-Ginsenoside Rg3","Jatrorrhizine chloride","Fraxinellone","Neochlorogenic acid","Sec-O-Glucosylhamaudol","Huperzine B","(+)-Isocorynoline","Cyanidin-3-O-glucoside chloride"]
[null,"b","Empty","S8519","S8648","S9035","S9080","S9107","S9140","S9174","S9236","S9260","S9313","Empty"]
[{"$nulls":3},"A-317491","ACY-738","Isovitexin","Anhydroicaritin","Glycitein","Pulegone","Xanthotoxol","α-Cyperone","Nodakenin","Atractylenolide III"]
[null,"c","Empty","S8564","S8689","S9039","S9085","S9108","S9142","S9176","S9239","S9263","S9314","Empty"]
[{"$nulls":3},"Verubecestat (MK-8931)","Abequolixron (RGX-104)","Albiflorin","Corynoline","Timosaponin A3","Sparteine","Pimpinellin","Isocorynoxeine","3-n-Butylphathlide","Atractylenolide II"]
[null,"d","Empty","S8573","S8691","S9040","S9087","S9112","S9146","S9178","S9243","S9272","S9315","Empty"]
[{"$nulls":3},"Sitravatinib (MGCD516)","ML204","Maslinic acid","Tenuifolin","Kaempferitrin","Anwuligan","Sinapine thiocyanate","Protosappanin B","Koumine","Praeruptorin A"]
[null,"e","Empty","S8575","S8694","S9047","S9088","S9115","S9149","S9179","S9249","S9293","S9326","Empty"]
[{"$nulls":3},"A2AR antagonist 1","CID16020046","Leonurine Hydrochloride","Calycosin-7-O-beta-D-glucoside","Wogonoside","Benzoylpaeoniflorin","Catharanthine hemitartrate","Securinine","Isoliquiritin","Scopolamine"]
[null,"f","Empty","S8583","S8695","S9049","S9092","S9118","S9151","S9184","S9252","S9295","S9348","Empty"]
[{"$nulls":3},"Repotrectinib (TPX-0005)","ML221","Parishin A","Norisoboldine","Beta-Asarone","Praeruptorin E","Forsythoside B","Corydaline","Dauricine","D-(+)-Trehalose Anhydrous"]
[null,"g","Empty","S8598","S8725","S9052","S9093","S9129","S9152","S9190","S9253","S9309","S9350","Empty"]
[{"$nulls":3},"S 38093","A-804598","Auraptene","Nardosinone","20(S)-Ginsenoside Rh1","Epiberberine","Oroxin B","Coixol","Micheliolide","Ethyl 4-Methoxycinnamate"]
[null,"h","Empty","S8603","S8788","S9065","S9099","S9134","S9154","S9201","S9256","S9310","S9361","Empty"]
[{"$nulls":3},"NGP 555","CH7057288","Songorine","Orientin","Spinosin","Chelidonine","Levistilide A","Isobavachin","Isorhychophylline","Coumarin-3-carboxylic acid"]
[]
[]
[]
[null,"Plate layout: L4000-16"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S9377","S9428","S9463","S9507","S5856","S6646","S9086","S2436","S6676","S2121","Empty"]
[{"$nulls":3},"Eugenyl acetate","Brazilin","Demecarium Bromide","(−)-Norepinephrine","Trifluoperazine","Ciforadenant (CPI-444)","Dihydrocapsaicin","Pranidipine","Ebselen","Licofelone (ML3000)"]
[null,"b","Empty","S9400","S9434","S9467","S9508","S6579","S6717","S9285","S2644","S9117","S2578","Empty"]
[{"$nulls":3},"Rhynchophylline","8-Gingerol","Thiothixene","Brimonidine","RCGD423","TCS-OX2-29","Fargesin","Lerisetron","(20S)Ginsenoside Rg2","1-Phenylbiguanide"]
[null,"c","Empty","S9401","S9443","S9469","S9509","S6583","S6726","S9138","S2645","S9145","S2595","Empty"]
[{"$nulls":3},"3,6'-Disinapoyl sucrose","Schisantherin B","Haloperidol Decanoate","Tiapride Hydrochloride","Apraclonidine HCl","MK1064","Picfeltarraenin IA","SIB 1757","Solamargine","FK-3311"]
[null,"d","Empty","S9408","S9446","S9470","S9510","S6602","S6733","S2272","S6634","S9290","S2642","Empty"]
[{"$nulls":3},"Beta-Elemonic acid","7,8-dihydrokawain","Penbutolol Sulfate","Protriptyline hydrochloride","TB5","Edonerpic maleate","Indoprofen","SAR7334","Linarin","1-Naphthyl PP1(1-NA-PP1)"]
[null,"e","Empty","S9409","S9457","S9472","S9511","S6619","S6735","S2418","S6649","S0160","S2646","Empty"]
[{"$nulls":3},"Kavain","Phensuximide","Oxtriphylline","Crocin I","ABT 702 dihydrochloride","JD-5037","Frentizole","E7046 (ER-886406)","Toloxatone (MD69276)","VU0238429"]
[null,"f","Empty","S9413","S9459","S9475","S9560","S6637","S6746","S2419","S6657","S0222","S2649","Empty"]
[{"$nulls":3},"Yangonin","Mecamylamine Hydrochloride","Hupehenine","Anisodamine Hydrobromide","HC-067047","APD668","Eprobemide","2-Aminoethyl Diphenylborinate (2-APB)","Lvguidingan","SB 200646"]
[null,"g","Empty","S9418","S9460","S9487","S9563","S6638","S8901","S2421","S6659","S0295","S2650","Empty"]
[{"$nulls":3},"Parishin B","Ethotoin","Praeruptorin C","Evodine","AMG-333","Taletrectinib (DS-6051b)","PF-04457845","Rimegepant (BMS-927711)","Anavex 2-73 HCl","RN-1734"]
[null,"h","Empty","S9427","S9461","S9502","S9566","S6644","S9050","S2434","S6665","S0779","S6615","Empty"]
[{"$nulls":3},"Tabersonine","Benzonatate","Madecassic acid","Bepridil hydrochloride","Radiprodil (RGH-896)","Boldine","IDRA-21","Sparsentan (PS-433540, RE-021)","Pirenperone","ATB 346"]
[]
[]
[]
[null,"Plate layout: L4000-17"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S6685","S8933","S0305","S3216","S3273","S6803","S0106","S0541","S0783","S2985","Empty"]
[{"$nulls":3},"Mavacoxib","ONO-7475","RO1138452","Uridine 5'-diphosphoglucose disodium salt","Hypericin","1-BCP","BD-1047 dihydrobromide","Dazoxiben hydrochloride","VU0119498","N-Acetyl-5-hydroxytryptamine"]
[null,"b","Empty","S6686","S0016","S0325","S3217","S3283","S6850","S0141","S0552","S0812","S3311","Empty"]
[{"$nulls":3},"SC-560","SN-6","Treprostinil sodium","Brilliant Blue G","Marmesin","NE 52-QQ57","NQ301","BNC210","SR59230A","Myosmine"]
[null,"c","Empty","S6780","S0116","S0398","S3235","S3291","S6853","S0165","S0721","S0826","S3370","Empty"]
[{"$nulls":3},"TFAP","Piperoxan hydrochloride","Astemizole","Sinapine","Myristicin","ONC206","Ampalex (CX-516)","Ticlopidine","A-740003","3-Methoxytyramine hydrochloride"]
[null,"d","Empty","S6787","S0174","S0405","S3236","S3293","S6906","S0412","S0750","S0827","S6907","Empty"]
[{"$nulls":3},"KN-93","TRPM8 antagonist 2","AF-353","Mesaconitine","Gardenoside","Capric acid","Bay 59-3074","GFB-8438","LM22A-4","Rapastinel (GLYX-13)"]
[null,"e","Empty","S6795","S0191","S0457","S3245","S3294","S6910","S0486","S0759","S0869","S6920","Empty"]
[{"$nulls":3},"VU0357017 Hydrochloride","BD1063 2HCL","DREADD agonist 21","Nodakenetin","Demethyl-Coclaurine","Preladenant","Hoechst 34580","FPL 62064","Carbetapentane","SEA0400"]
[null,"f","Empty","S6804","S0225","S0758","S3246","S3298","S7394","S0495","S0766","S0870","S6934","Empty"]
[{"$nulls":3},"CX546","IMR-1A","BX430","Picfeltarraenin IB","Caulophylline (N-Methylcytisine)","MDL-28170","BI-671800","RHC 80267","Barnidipine","AMG-9810"]
[null,"g","Empty","S6815","S0297","S0924","S3255","S6664","S9662","S0496","S0772","S0977","S6948","Empty"]
[{"$nulls":3},"CDN1163","UCPH-101","Pteryxin","Pectolinarigenin","Gefapixant","UNC2025","PF-04995274","L-732138","AC1903","Lanreotide"]
[null,"h","Empty","S6838","S0303","S0973","S3261","S6760","S0000","S0498","S0782","S2953","S6950","Empty"]
[{"$nulls":3},"BCTC","CGP52432","Wilforgine","Myrislignan","LM22B-10","Cav 2.2 blocker 1","Namodenoson (CF-102)","VU0238441","Dooku1","PRE-084 hydrochloride"]
[]
[]
[]
[null,"Plate layout: L4000-18"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S9271","S2995","S5181","S5777","S5949","S9742","S5980","S9842","S0897","E0026","Empty"]
[{"$nulls":3},"Pulchinenoside A","4-Hydroxyphenylpyruvic acid","Levobupivacaine","Ipratropium bromide monohydrate","Metoclopramide hydrochloride hydrate","Indisulam","Losartan Carboxylic Acid (EXP-3174)","MCU-i4","Cyclizine","ML-SI3"]
[null,"b","Empty","S9686","S3913","S5184","S5786","S5954","S9789","S6301","S9886","S1335","E0031","Empty"]
[{"$nulls":3},"NBQX (FG9202)","Pimethixene maleate","Dexamethasone palmitate","Bromfenac sodium hydrate","L-(-)-α-Methyldopa hydrate","JHU37152","MPP+ iodide","Biocytin","VX-150","RN-1747"]
[null,"c","Empty","S9719","S4423","S5185","S5789","S5955","S9790","S6347","E0009","S2963","E0076","Empty"]
[{"$nulls":3},"CB-103","Emamectin Benzoate","Perospirone","Propafenone","Thiamine nitrate","JHU37160","5'-N-Ethylcarboxamidoadenosine (NECA)","Harmane","WS-12","Simufilam dihydrochloride"]
[null,"d","Empty","S0032","S4435","S5191","S5860","S5965","S0272","S6947","E0020","S3584","E0137","Empty"]
[{"$nulls":3},"Batefenterol","Metamizole sodium hydrate","Cinacalcet","Larotrectinib","Urapidil","Derenofylline (SLV320)","MK6-83","Lupenone","Luzindole","GV-58"]
[null,"e","Empty","S0717","S4481","S5192","S5864","S5966","S0326","S6981","E0028","S6070","E0165","Empty"]
[{"$nulls":3},"Varenicline (CP 526555) dihydrochloride","Guanabenz","S-(+)-Ketoprofen","Levocetirizine","Amlodipine maleate","Olodanrigan (EMA401)","Glycerol phenylbutyrate","9-Phenanthrol","CBA (TRPM4-IN-5)","Phenelzine sulfate"]
[null,"f","Empty","S0761","S4483","S5196","S5898","S5973","S0446","S6985","S0019","S6694","E0172","Empty"]
[{"$nulls":3},"Desmethyl Celecoxib","Iproniazid phosphate","Promethazine","Efonidipine hydrochloride monoethanolate","Methylprednisolone Acetate","TCN 201","Varenicline","JNJ-10229570","Grapiprant (CJ-023,423)","Imidacloprid"]
[null,"g","Empty","S0821","S4486","S5489","S5942","S5981","S0838","S7538","S0529","S9498","E0176","Empty"]
[{"$nulls":3},"Pamicogrel","Thiamine monochloride","Prednisone acetate","Bisoprolol","S(-)-Propranolol hydrochloride","S-(4-Nitrobenzyl)-6-thioinosine (NBMPR)","RS-102895 Hydrochloride","PBD-150","5-BDBD","Dinotefuran"]
[null,"h","Empty","S2945","S4713","S5770","S5947","S8033","S4485","S7848","S0720","S9926","E0356","Empty"]
[{"$nulls":3},"SCH-442416","Atropine","Pizotifen","Amitriptyline","6-Iodopravadoline (AM630)","Olodaterol (BI 1744)","QX-314 chloride","PNU-282987","ML-SA1","MIPS521"]
[]
[]
[]
[null,"Plate layout: L4000-19"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","E1002","S0111","S0762","S3405","E0101","E0458","E0777","E0936","E2517","P1165","Empty"]
[{"$nulls":3},"Setmelanotide (RM-493)","Taprenepag","SC 236","CRANAD-2","AZD-6280","RTICBM-189","Z944","IGS-1.76","WAY-388264-A","Pep2m, myristoylated (TFA)"]
[null,"b","Empty","P1211","S0282","S0893","S3535","E0105","E0472","E0778","E0949","E2521","P1220","Empty"]
[{"$nulls":3},"Apelin-13","YL 0919","SB-200646A","Deudextromethorphan (AVP-786)","ICA-27243","BMS-986122","o-3M3FBS","Mebicar","WAY-327157","tat-nr2b9c"]
[null,"c","Empty","P1212","S0318","S0896","S6087","E0125","E0484","E0789","E0960","E2632","S8421","Empty"]
[{"$nulls":3},"(Ala13)-Apelin-13","Ansofaxine hydrochloride","DSP-4 HCl","Indophagolin","Raclopride","CNQX","SC-58125","RO5186582","Norharmane","Fenebrutinib (GDC-0853)"]
[null,"d","Empty","S0007","S0319","S1970","S7478","E0334","E0500","E0799","E1050","E2684","E2232","Empty"]
[{"$nulls":3},"RO 5028442 (RG7713)","D3-βArr","VU-29","AF38469","BAMB-4","Firocoxib (ML 1785713)","VU 0365114","PEAQX","Icilin","Guvacine hydrochloride"]
[null,"e","Empty","S0009","S0452","S2089","S9849","E0363","E0529","E0809","E1093","P1008","S0014","Empty"]
[{"$nulls":3},"Asimadoline hydrochloride","NP118809","Fenoldopam","5-(N-Ethyl-N-isopropyl)-Amiloride (EIPA)","Compound 11","Metipranolol","Timapiprant Sodium","DNPH1i(N6-benzyladenosine)","Carbetocin Acetate","HT-2157"]
[null,"f","Empty","S0017","S0518","S2174","E0070","E0379","E0535","E0814","E1265","P1095","S0036","Empty"]
[{"$nulls":3},"Lu-135252","NS 1738","Hydroxyflutamide (Hydroxyniphtholide)","4F 4PP oxalate","SEN12333","WAY-303290","Masitinib mesylate","Deschloroclozapine","BAM (8-22)","PF-06869206"]
[null,"g","Empty","S0073","S0521","S2917","E0079","E0388","E0599","E0826","E2356","P1108","S0082","Empty"]
[{"$nulls":3},"BI 01383298","PNU-282987 S enantiomer free base","Cutamesine Dihydrochloride","Compound W","WQ 1","Arecaidine hydrochloride","Levamlodipine Besylate","Tandospirone","Bremelanotide Acetate","PH-002"]
[null,"h","Empty","S0080","S0535","S2957","E0083","E0408","E0755","E0829","E2390","P1116","S0113","Empty"]
[{"$nulls":3},"SNAP94847 hydrochloride","FK962","Encenicline (EVP-6124) hydrochloride","TSHR antagonist S37","JP1302","Guvacoline hydrochloride","Nitrocaramiphen hydrochloride","Thalidomide-5-NH2-CH2-COOH","Epitalon","Eptapirone"]
[]
[]
[]
[null,"Plate layout: L4000-20"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S0164","S1989","S6731","S8890","E1258","E4112","E1368","E2901","E4032","E2985","Empty"]
[{"$nulls":3},"AZD-7325","GABAA receptor agent 1","Eliprodil (SL-820715)","MK-8719","Pridopidine","Menthol","PD173212","(-)-Isoproterenol hydrochloride","5'-Deoxy-5'-(methylthio)adenosine","Capadenoson"]
[null,"b","Empty","S0313","S2975","S6835","S9608","E1259","E4298","E1410","E2943","S1423","E4024","Empty"]
[{"$nulls":3},"Volinanserin","CarboxyaMidotriazole orotate","3-deazaadenosine","Etrumadenant (AB928)","DNQX","(-)-Carvone","Fluspirilene","Pifithrin-β","Dobutamine HCl","Poly-D-lysine hydrobromide"]
[null,"c","Empty","S0447","S3191","S8107","E0041","E2227","E1119","E2153","E2944","S8212","E4031","Empty"]
[{"$nulls":3},"ASP7663","Azumolene","GSK1016790A","Tolebrutinib (SAR442168)","GLN-1062","EG00229","TRYPTAMINE HYDROCHLORIDE","Norepinephrine hydrochloride","Olcegepant","8-Cyclopentyl-1,3-dimethylxanthine"]
[null,"d","Empty","S0476","S3376","S8114","E0077","E2515","E1218","E2868","E2948","E0109","E4042","Empty"]
[{"$nulls":3},"SCH-23390 hydrochloride","RBPJ Inhibitor-1 (RIN1)","ICI-118551 Hydrochloride","Simufilam","JT010","K6PC-5","Naloxegol Oxalate","β-Amyloid (25-35)","Fezolinetant","5,5-Dimethyl-1-pyrroline N-oxide"]
[null,"e","Empty","S0702","S3510","S8524","E0164","E2809","E1220","E2871","E2964","E1579","E4450","Empty"]
[{"$nulls":3},"α-Conotoxin GI","NLX-101","Edicotinib(JNJ-40346527)","Antazoline Phosphate","WAY-328168","CBR-470-1","Trovafloxacin Mesylate","Norepinephrine tartrate","UCL-TRO-1938","N6-Cyclopentyladenosine"]
[null,"f","Empty","S0825","S3520","S8600","E0357","E2848","E1256","E2874","E2984","E1603","E4477","Empty"]
[{"$nulls":3},"MDR-652","AZ10606120 dihydrochloride","Elenbecestat","Eliapixant","Afoxolaner","Ibotenic acid","Sofpironium bromide","GSK-7975A","ACT001(DMAMCL)","Lumateperone"]
[null,"g","Empty","S0862","S6639","S8636","E1247","P1106","E1310","E2875","E2993","E1742","S6952","Empty"]
[{"$nulls":3},"L-765314","BAY-545","Selitrectinib (LOXO-195)","SR95531","D-JNKI-1","DPCPX","Levobunolol(l-Bunolol) hydrochloride","Ruthenium Red","Reversan","MK-28"]
[null,"h","Empty","S1575","S6668","S8720","E1257","P1208","E1333","E2880","E2998","E1773","S7236","Empty"]
[{"$nulls":3},"RO4929097","NVS-ZP7-4","Imaradenant (AZD4635)","(R,S)-3,5-DHPG Hydrochloride","PMX 205","wiskostatin","methylnaltrexone bromide","Acetylthiocholine iodide","Fasoracetam (NS 105)","Cariprazine hydrochloride"]
[]
[]
[]
[null,"Plate layout: L4000-21"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S8395","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"INDY"]
[null,"b","Empty","E1280","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Ubrogepant"]
[null,"c","Empty","E1469","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"ITF3756"]
[null,"d","Empty","E4026","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Poly(2-hydroxyethyl methacrylate)"]
[null,"e","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"f","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"g","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"h","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[]
[]
[]
[null,"Plate layout: L4000-22"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1338","S1893","S2507","S3737","S4117","S4700","S5137","S5632","S7548","S2996","Empty"]
[{"$nulls":3},"Gabapentin HCl","D-glutamine","Salbutamol Sulfate","Cangrelor Tetrasodium","Histamine Phosphate","4-Aminobutyric acid (GABA)","O-Phospho-L-serine","L-aspartic Acid","Rilmenidine Phosphate","L-DAB HBR"]
[null,"b","Empty","S1339","S1939","S2560","S3748","S4121","S4702","S5252","S5674","P1017","S3326","Empty"]
[{"$nulls":3},"Galanthamine HBr","Levamisole hydrochloride","Amiloride HCl dihydrate","Acamprosate Calcium","Succinylcholine Chloride Dihydrate","Sarcosine","Ozagrel sodium","Lodoxamide Tromethamine","Octreotide (SMS 201-995) acetate","Phytic acid dipotassium salt"]
[null,"c","Empty","S1345","S1984","S2568","S3852","S4127","S4703","S5267","S6023","P1030","S3346","Empty"]
[{"$nulls":3},"Granisetron HCl","Ticlopidine HCl","Neomycin sulfate","L-Theanine","Terbutaline Sulfate","Choline bitartrate","Nylidrin Hydrochloride","Creatine monohydrate","Salmon Calcitonin Acetate","1-Methylnicotinamide chloride"]
[null,"d","Empty","S1375","S1998","S3048","S3989","S4137","S4721","S5362","S6176","P1049","S3368","Empty"]
[{"$nulls":3},"Dorzolamide HCl","D-Cycloserine","Solifenacin succinate","L-​Histidine","Eprazinone 2HCl","L-Glutamic acid monosodium salt","Citicoline","Scyllo-Inositol","GHRP-2","Uridine-5'-diphosphate disodium salt"]
[null,"e","Empty","S1440","S1999","S3050","S4008","S4180","S4740","S5496","S6224","P1085","S9664","Empty"]
[{"$nulls":3},"Varenicline Tartrate (CP 526555-18)","Sodium butyrate","Palonosetron HCl","Pemirolast potassium","Nefopam HCl","Sodium ferulate","Guanethidine Monosulfate","(R)-Serine","Angiotensin II human Acetate","Colivelin"]
[null,"f","Empty","S1506","S2133","S3072","S4027","S4328","S4972","S5526","S6266","S4933","S4494","Empty"]
[{"$nulls":3},"Perindopril Erbumine","Gabapentin","(R)-baclofen","Flavoxate HCl","Guanethidine Sulfate","Choline Glycerophosphate","β-Alanine","(S)-Glutamic acid","Lithium carbonate","Methionine"]
[null,"g","Empty","S1518","S2462","S3146","S4028","S4360","S5097","S5588","S6592","S3203","S5022","Empty"]
[{"$nulls":3},"Ibuprofen Lysine","Donepezil HCl","Tripelennamine HCl","Dexamethasone Sodium Phosphate","Tolmetin Sodium","Methotrexate disodium","Creatine","Diquafosol Tetrasodium","D-Alanine","Varenicline Hydrochloride"]
[null,"h","Empty","S1749","S2490","S3662","S4069","S4575","S5131","S5612","S7537","P1088","S5956","Empty"]
[{"$nulls":3},"L-Glutamine","Neostigmine Bromide","Pirenzepine dihydrochloride","Hexamethonium Dibromide","Pralidoxime chloride","Homotaurine","Isonipecotic acid","LB-100","Lanreotide acetate","Dexamethasone phosphate disodium"]
[]
[]
[]
[null,"Plate layout: L4000-23"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S9820","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Angiotensin (1-7)"]
[null,"b","Empty","E2691","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"BAPTA tetrapotassium salt"]
[null,"c","Empty","S8416","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"PACAP 6-38"]
[null,"d","Empty","E1246","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"D-AP5"]
[null,"e","Empty","E2979","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"DL-AP5 (2-APV)"]
[null,"f","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"g","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"h","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[]
[]
[]
[null,"Plate layout: L4000-24"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1424","S2035","S3721","S5499","S9257","S8274","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Prazosin HCl","Epalrestat (ONO-2235)","Bilastine","Amantadine","Acetylshikonin","STO-609"]
[null,"b","Empty","S1507","S2047","S3821","S5577","S3304","S9464","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Irbesartan","Lornoxicam","Nuciferine","6-Biopterin","Stylopine","Tranylcypromine Sulfate"]
[null,"c","Empty","S1615","S2110","S4033","S6001","S6345","S4586","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Risperidone","Vinpocetine","Sennoside A","pomaglumetad (LY404039)","3-Nitro-L-tyrosine","4-Chloro-DL-phenylalanine"]
[null,"d","Empty","S1642","S2232","S4218","S6618","E0100","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Methyldopa","Ketanserin","Amoxapine","JNJ-42153605","Sodium ionophore III"]
[null,"e","Empty","S1707","S2251","S4262","S6632","E0382","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Eplerenone (CGP 30083)","(-)-Huperzine A (HupA)","Ebastine","Mirogabalin (DS-5565)","W-84 Dibromide"]
[null,"f","Empty","S1724","S2582","S4654","S7400","E0524","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Paliperidone","Trazodone HCl","Netupitant","ISRIB (trans-isomer)","Spinosad"]
[null,"g","Empty","S1929","S3041","S5018","S8012","E0784","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Irsogladine","Droxidopa","Mebhydrolin napadisylate","Otenabant (CP-945598) HCl","MAO-B-IN-2"]
[null,"h","Empty","S1986","S3064","S5427","S9209","E0831","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Meclizine 2HCl","Ambroxol HCl","Alloxazine","Tritetradecanoin","Pseudocoptisine chloride"]
[]
[]
[]
[null,"Plate layout: L4000-25"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1911","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Disodium Cromoglycate"]
[null,"b","Empty","S2106","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Azasetron HCl"]
[null,"c","Empty","S4067","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Deferiprone"]
[null,"d","Empty","S4694","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Alosetron Hydrochloride"]
[null,"e","Empty","S2050","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Strontium Ranelate"]
[null,"f","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"g","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"h","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]

{"sheet":"L4000-Neuronal-1737 cpds","index":1,"n_rows":1738,"n_cols":23,"rows_kept":1738}
["Cat","Name","Plate Location","Rack Number","Formulation","Target","Pathway","Information","M.w.","CAS Number","DMSO (mg/mL)Max Solubility","DMSO (mM)Max Solubility","Water (mg/mL)Max Solubility","Water (mM)Max Solubility","URL","Formula","Form","Synonyms","SMILES","ALogP","HBA_Count","HBD_Count","RotatableBond"]
["S1006","Saracatinib (AZD0530)","a2","L4000-01","in 10mM DMSO","Autophagy,EGFR,Src","Angiogenesis","Saracatinib (AZD0530) is a potent Src inhibitor with IC50 of 2.7 nM in cell-free assays, and potent to c-Yes, Fyn, Lyn, Blk, Fgr and Lck; less active for Abl and EGFR (L858R and L861Q). Saracatinib induces autophagy. Phase 2/3.",542.03,"379231-04-6",{"v":35,"d":"35.00"},64.57,"<1","N/A","http://selleckchem.com/products/AZD0530.html","C27H32ClN5O5","free base","N/A","CN1CCN(CCOC2=CC(=C3C(=NC=NC3=C2)NC4=C(Cl)C=CC5=C4OCO5)OC6CCOCC6)CC1",3.814,7,1,8]
["S1039","Rapamycin (AY-22989)","b2","L4000-01","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,Autophagy,mTOR","PI3K/Akt/mTOR","Rapamycin (AY-22989, Rapamune, Sirolimus, NSC-2260804,AY-22989) is a specific mTOR inhibitor with IC50 of ~0.1 nM HEK293 cells.",914.18,"53123-88-9",{"v":20,"d":"20.00"},21.88,"<1","N/A","http://selleckchem.com/products/Rapamycin.html","C51H79NO13","free base","Rapamune, Sirolimus, NSC-2260804,AY-22989","COC1CC(CCC1O)CC(C)C2CC(=O)C(C)\\C=C(/C)C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC",6.295,10,2,6]
["S1064","Masitinib (AB1010)","c2","L4000-01","in 10mM DMSO","c-Kit,PDGFR","Protein Tyrosine Kinase","Masitinib is a novel inhibitor for Kit (c-Kit) and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms. Phase 3.",498.64,"790299-79-5",{"v":100,"d":"100.00"},200.55,"<1","N/A","http://selleckchem.com/products/Masitinib-(AB1010).html","C28H30N6OS","free base","N/A","CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC(=C(C)C=C3)NC4=NC(=CS4)C5=CC=CN=C5",4.475,3,2,7]
["S1066","SL-327","d2","L4000-01","in 10mM DMSO","MEK","MAPK","SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/ 0.22 μM, no activity towards Erk1, MKK3, MKK4, c-JUN, PKC, PKA, or CamKII;capable of transport through the blood-brain barrier.",335.35,"305350-87-2",{"v":67,"d":"67.00"},199.79,"<1","N/A","http://selleckchem.com/products/SL327.html","C16H12F3N3S","free base","N/A","NC(\\SC1=CC=C(N)C=C1)=C(C#N)/C2=C(C=CC=C2)C(F)(F)F",3.705,0,2,4]
["S1075","SB216763","e2","L4000-01","in 10mM DMSO","Autophagy,GSK-3","PI3K/Akt/mTOR","SB216763 is a potent and selective GSK-3 inhibitor with IC50 of 34.3 nM for GSK-3α and equally effective at inhibiting human GSK-3β. SB216763 activates autophagy.",371.22,"280744-09-4",{"v":23,"d":"23.00"},61.96,"<1","N/A","http://selleckchem.com/products/SB-216763.html","C19H12N2O2Cl2","free base","N/A","C[N]1C=C(C2=C1C=CC=C2)C3=C(C(=O)NC3=O)C4=CC=C(Cl)C=C4Cl",4.391,2,1,2]
["S1107","Danusertib (PHA-739358)","f2","L4000-01","in 10mM DMSO","Apoptosis related,Aurora Kinase,Autophagy,Bcr-Abl,c-RET,FGFR,Trk receptor","Cell Cycle","Danusertib (PHA-739358) is an Aurora kinase inhibitor for Aurora A/B/C with IC50 of 13 nM/79 nM/61 nM in cell-free assays, modestly potent to Abl, TrkA, c-RET and FGFR1, and less potent to Lck, VEGFR2/3, c-Kit, CDK2, etc. Danusertib induces apoptosis, cell cycle arrest, and autophagy. Phase 2.",474.55,"827318-97-8",{"v":95,"d":"95.00"},200.19,"<1","N/A","http://selleckchem.com/products/PHA-739358(Danusertib).html","C26H30N6O3","free base","N/A","COC(C(=O)N1CC2=C(C1)C(=N[NH]2)NC(=O)C3=CC=C(C=C3)N4CCN(C)CC4)C5=CC=CC=C5",2.337,4,2,6]
["S1120","Everolimus (RAD001)","g2","L4000-01","in 10mM DMSO","Apoptosis related,Autophagy,FKBP,mTOR","PI3K/Akt/mTOR","Everolimus (RAD001, SDZ-RAD, Afinitor) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM in a cell-free assay. Everolimus induces cell apoptosis and autophagy and inhibits tumor cells proliferation.",958.22,"159351-69-6",{"v":100,"d":"100.00"},104.36,"<1","N/A","http://selleckchem.com/products/Everolimus(RAD001).html","C53H83NO14","free base","RAD001,SDZ-RAD, Afinitor","COC1CC(CCC1OCCO)CC(C)C2CC(=O)C(C)\\C=C(C)\\C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC",6.164,11,2,9]
["S1124","BMS-754807","h2","L4000-01","in 10mM DMSO","c-Met,IGF-1R,RON,Trk receptor","Protein Tyrosine Kinase","BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM in cell-free assays, less potent to Met (c-Met), Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc. Phase 2.",461.49,"1001350-96-4",{"v":92,"d":"92.00"},199.35,"<1","N/A","http://selleckchem.com/products/BMS-754807.html","C23H24FN9O","free base","N/A","CC1(CCCN1C2=N[N]3C=CC=C3C(=N2)NC4=N[NH]C(=C4)C5CC5)C(=O)NC6=CC=C(F)N=C6",4.069,5,3,6]
["S1129","SRT1720 HCl","a3","L4000-01","in 10mM DMSO","Autophagy,Sirtuin","Epigenetics","SRT1720 HCl is a selective SIRT1 activator with EC50 of 0.16 μM in a cell-free assay, but is >230-fold less potent for SIRT2 and SIRT3. SRT1720 induces autophagy.",506.02,"1001645-58-4",{"v":38,"d":"38.00"},{"v":75.1,"d":"75.10"},"<1","N/A","http://selleckchem.com/products/SRT1720.html","C25H23N7OS.HCl","Hydrochloride","N/A","Cl.O=C(NC1=CC=CC=C1C2=C[N]3C(=CSC3=N2)CN4CCNCC4)C5=NC6=CC=CC=C6N=C5",3.018,4,2,5]
["S1152","PLX-4720","b3","L4000-01","in 10mM DMSO","Raf","MAPK","PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity for B-RafV600E than wild-type B-Raf.",413.83,"918505-84-7",{"v":83,"d":"83.00"},200.57,"<1","N/A","http://selleckchem.com/products/PLX-4720.html","C17H14ClF2N3O3S","free base","N/A","CCC[S](=O)(=O)NC1=CC=C(F)C(=C1F)C(=O)C2=C[NH]C3=NC=C(Cl)C=C23",3.435,4,2,6]
["S1168","Valproic Acid (NSC 93819) sodium salt","c3","L4000-01","in 10mM DMSO","Autophagy,GABA Receptor,HDAC,Mitophagy,Notch,PGC-1α","Neuronal Signaling","Valproic Acid sodium salt (NSC 93819, Sodium valproate) is a HDAC inhibitor by selectively inducing proteasomal degradation of HDAC2, used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. Valproic acid induces Notch1 signaling in small cell lung cancer (SCLC) cells. Valproic acid is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α.",166.19,"1069-66-5",{"v":33,"d":"33.00"},198.57,{"v":33,"d":"33.00"},198.57,"http://selleckchem.com/products/Sodium-valproate.html","C8H15NaO2","Sodium salt","Sodium valproate,NSC 93819,2-Propylpentanoic Acid","CCCC(CCC)C(=O)O[Na]",1.275,0,0,5]
["S1189","Aprepitant (MK-0869)","d3","L4000-01","in 10mM DMSO","CSF-1R,HIV,Interleukins,Neurokinin Receptor,TNF-alpha","Neuronal Signaling","Aprepitant (MK-0869, L-754030, Emend) is a potent and selective neurokinin-1 receptor antagonist with IC50 of 0.1 nM. Aprepitant reduces levels of pro-inflammatory cytokines including G-CSF, IL-6, IL-8 and TNFα. Aprepitant inhibits HIV infection of human macrophages.",534.43,"170729-80-3",{"v":107,"d":"107.00"},200.21,"<1","N/A","http://selleckchem.com/products/Aprepitant.html","C23H21F7N4O3","free base","MK-0869, L-754030, Emend","CC(OC1OCCN(CC2=NNC(=O)N2)C1C3=CC=C(F)C=C3)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F",4.635,4,2,8]
["S1193","Thalidomide (K17)","e3","L4000-01","in 10mM DMSO","E3 Ligase ,E3 ligase Ligand,TNF-alpha","Ubiquitin","Thalidomide (K17) was introduced as a sedative drug, immunomodulatory agent and also is investigated for treating symptoms of many cancers. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1.",258.23,"50-35-1",{"v":51,"d":"51.00"},{"v":197.5,"d":"197.50"},"<1","N/A","http://selleckchem.com/products/Thalidomide.html","C13H10N2O4","free base","K17","O=C1CCC(N2C(=O)C3=C(C=CC=C3)C2=O)C(=O)N1",0.097,4,1,1]
["S1201","Dimesna","f3","L4000-01","in 10mM DMSO","Others","Others","Dimesna (BNP-7787) is an uroprotective agent used to decrease urotoxicity.",326.34,"16208-51-8",{"v":65,"d":"65.00"},199.18,{"v":65,"d":"65.00"},199.18,"http://selleckchem.com/products/Dimesna.html","C4H8Na2O6S4","Disodium salt","BNP-7787","[Na+].[Na+].[O-][S](=O)(=O)CCSSCC[S]([O-])(=O)=O",-4.295,0,0,7]
["S1204","Melatonin (NSC 113928)","g3","L4000-01","in 10mM DMSO","Apoptosis related,ATF/CREB & c-Fos/c-Jun,Autophagy,COX,Mitophagy,MT Receptor","GPCR & G Protein","Melatonin (NSC 113928, NSC 56423, N-Acetyl-5-methoxytryptamine,MT) is a MT receptor agonist, used as a dietary supplement. Melatonin is a selective ATF-6 inhibitor and downregulates COX-2. Melatonin enhances mitophagy and regulates the homeostasis of apoptosis and autophagy.",232.28,"73-31-4",{"v":47,"d":"47.00"},202.34,"<1","N/A","http://selleckchem.com/products/Melatonin.html","C13H16N2O2","free base","NSC 56423, N-Acetyl-5-methoxytryptamine,NSC 113928,MT","COC1=CC2=C([NH]C=C2CCNC(C)=O)C=C1",1.555,2,2,4]
["S1206","Bisoprolol fumarate","h3","L4000-01","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Bisoprolol fumarate (EMD33512) is a selective type β1 adrenergic receptor blocker.",441.52,"104344-23-2",{"v":88,"d":"88.00"},199.31,{"v":88,"d":"88.00"},199.31,"http://selleckchem.com/products/Bisoprolol-Fumarate.html","C22H35NO8","fumarate","EMD33512","CC(C)NCC(O)COC1=CC=C(COCCOC(C)C)C=C1.OC(=O)\\C=C\\C(O)=O",-0.635,5,2,14]
["S1243","Agomelatine (S20098)","a4","L4000-01","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Agomelatine (Valdoxan, Melitor, Thymanax,S20098) is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.",{"v":243.3,"d":"243.30"},"138112-76-2",{"v":48,"d":"48.00"},197.29,"<1","N/A","http://selleckchem.com/products/Agomelatine.html","C15H17NO2","free base","Valdoxan, Melitor, Thymanax,S20098","COC1=CC2=C(CCNC(C)=O)C=CC=C2C=C1",{"v":2.17,"d":"2.170"},2,1,4]
["S1245","Latrepirdine 2HCl","b4","L4000-01","in 10mM DMSO","5-HT Receptor,GluR,Histamine Receptor","Neuronal Signaling","Latrepirdine is an orally active,and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihistamine drug.",392.37,"97657-92-6",{"v":24,"d":"24.00"},61.17,"<1","N/A","http://selleckchem.com/products/Dimebon.html","C21H25N3.2HCl","Dihydrochloride","N/A","Cl.Cl.CN1CCC2=C(C1)C3=C(C=CC(=C3)C)[N]2CCC4=CC=C(C)N=C4",4.769,1,0,3]
["S1255","Nepafenac","c4","L4000-01","in 10mM DMSO","COX","Neuronal Signaling","Nepafenac (AHR 9434, AL 6515) is a prodrug of amfenac that acts as an inhibitor of COX-1 and COX-2 activity, used in the treatment of pain and inflammation associated with cataract surgery.",254.28,"78281-72-8",{"v":50,"d":"50.00"},196.63,"<1","N/A","http://selleckchem.com/products/Nepafenac.html","C15H14N2O2","free base","AHR 9434, AL 6515","NC(=O)CC1=CC=CC(=C1N)C(=O)C2=CC=CC=C2",1.524,2,2,4]
["S1256","Rufinamide","d4","L4000-01","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Rufinamide (CGP 33101,E 2080,RUF 331,Banzel) is a voltage-gated sodium channel blocker, used an anticonvulsant medication.",238.19,"106308-44-5",{"v":18,"d":"18.00"},75.57,"<1","N/A","http://selleckchem.com/products/Rufinamide.html","C10H8F2N4O","free base","CGP 33101,E 2080,RUF 331,Banzel","NC(=O)C1=C[N](CC2=C(F)C=CC=C2F)N=N1",1.437,3,1,3]
["S1258","Prasugrel","e4","L4000-01","in 10mM DMSO","P2 Receptor","Neuronal Signaling","Prasugrel (Effient, Efient, Prasita,CS-747, LY640315,PCR 4099) is a thienopyridine ADP receptor (P2Y12) antagonist, used for the reduction of thrombotic cardiovascular events.",373.44,"150322-43-3",{"v":30,"d":"30.00"},80.33,"<1","N/A","http://selleckchem.com/products/Prasugrel.html","C20H20FNO3S","Free Base","Effient, Efient, Prasita,CS-747, LY640315,PCR 4099","CC(=O)OC1=CC2=C(CCN(C2)C(C(=O)C3CC3)C4=CC=CC=C4F)S1",3.801,3,0,6]
["S1259","Ramelteon","f4","L4000-01","in 10mM DMSO","MT Receptor","GPCR & G Protein","Ramelteon (TAK-375) is a novel melatonin receptor agonist for human MT1 and MT2 receptors and chick forebrain melatonin receptors with Ki of 14 pM, 112 pM and 23.1 pM, respectively.",259.34,"196597-26-9",{"v":52,"d":"52.00"},200.51,"<1","N/A","http://selleckchem.com/products/Ramelteon.html","C16H21NO2","free base","TAK-375","CCC(=O)NCCC1CCC2=CC=C3OCCC3=C12",2.826,2,1,4]
["S1261","Celecoxib (SC 58635)","g4","L4000-01","in 10mM DMSO","COX","Neuronal Signaling","Celecoxib (Celebrex, Celebra,SC 58635) is a selective COX-2 inhibitor with IC50 of 40 nM in Sf9 cells.",381.37,"169590-42-5",{"v":76,"d":"76.00"},199.28,"<1","N/A","http://selleckchem.com/products/Celecoxib.html","C17H14F3N3O2S","free base","Celebrex, Celebra,SC 58635","CC1=CC=C(C=C1)C2=CC(=N[N]2C3=CC=C(C=C3)[S](N)(=O)=O)C(F)(F)F",4.428,3,1,4]
["S1262","Avagacestat (BMS-708163)","h4","L4000-01","in 10mM DMSO","Beta Amyloid,Notch,Secretase","Proteases","Avagacestat (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.",520.88,"1146699-66-2",{"v":104,"d":"104.00"},199.66,"<1","N/A","http://selleckchem.com/products/BMS-708163.html","C20H17ClF4N4O4S","free base","N/A","NC(=O)C(CCC(F)(F)F)N(CC1=C(F)C=C(C=C1)C2=NOC=N2)[S](=O)(=O)C3=CC=C(Cl)C=C3",3.364,6,1,10]
["S1280","Amisulpride","a5","L4000-01","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Amisulpride (DAN-2163) is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.",369.48,"71675-85-9",{"v":73,"d":"73.00"},197.57,"<1","N/A","http://selleckchem.com/products/Amisulpride.html","C17H27N3O4S","free base","DAN-2163","CCN1CCCC1CNC(=O)C2=CC(=C(N)C=C2OC)[S](=O)(=O)CC",1.127,4,2,7]
["S1281","Aniracetam","b5","L4000-01","in 10mM DMSO","AMPA Receptor-kainate Receptor-NMDA Receptor","Neuronal Signaling","Aniracetam (RO 13-5057) is a nootropics and neuroprotective drug.",219.24,"72432-10-1",{"v":44,"d":"44.00"},200.69,"<1","N/A","http://selleckchem.com/products/Aniracetam.html","C12H13NO3","free base","RO 13-5057","COC1=CC=C(C=C1)C(=O)N2CCCC2=O",1.267,3,0,2]
["S1283","Asenapine maleate","c5","L4000-01","in 10mM DMSO","5-HT Receptor,Adrenergic Receptor","Neuronal Signaling","Asenapine maleate (Org 5222) is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder.",401.84,"85650-56-2",{"v":80,"d":"80.00"},199.08,"<1","N/A","http://selleckchem.com/products/Asenapine.html","C17H16ClNO.C4H4O4","Maleate","Org 5222","CN1CC2C(C1)C3=C(OC4=C2C=CC=C4)C=CC(=C3)Cl.OC(=O)\\C=C/C(O)=O",0.883,3,0,2]
["S1286","Budesonide","d5","L4000-01","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Budesonide(Labazenit) is a glucocorticoid steroid for the treatment of asthma, non-infectious rhinitis.",430.53,"51333-22-3",{"v":86,"d":"86.00"},199.75,"<1","N/A","http://selleckchem.com/products/Budesonide.html","C25H34O6","free base","Labazenit","CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC3(C)C2(O1)C(=O)CO",2.198,4,2,4]
["S1290","Celastrol (NSC 70931)","e5","L4000-01","in 10mM DMSO","Apoptosis related,Autophagy,Mitophagy,Proteasome","Proteases","Celastrol (NSC 70931, Tripterine) is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway. Celastrol inhibits dopaminergic neuronal death of Parkinson's disease through activating mitophagy.",450.61,"34157-83-0",{"v":90,"d":"90.00"},199.73,"<1","N/A","http://selleckchem.com/products/Celastrol.html","C29H38O4","free base","Tripterine","CC1=C(O)C(=O)C=C2C1=CC=C3C2(C)CCC4(C)C5CC(C)(CCC5(C)CCC34C)C(O)=O",5.475,2,1,1]
["S1291","Cetirizine DiHCl","f5","L4000-01","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Cetirizine DiHCl (Zyrtec, Reactine,UCB P071) is an antihistamine.",461.81,"83881-52-1",{"v":92,"d":"92.00"},199.22,{"v":92,"d":"92.00"},199.22,"http://selleckchem.com/products/Cetirizine-Dihydrochloride.html","C21H25ClN2O3.2HCl","Dihydrochloride","Zyrtec, Reactine,UCB P071","Cl.Cl.OC(=O)COCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3",1.217,2,0,8]
["S1293","Cilnidipine (FRC-8653)","g5","L4000-01","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Cilnidipine (FRC-8653) is a unique L-type and N-type calcium channel blocker, used for high blood pressure treatment.",492.52,"132203-70-4",{"v":99,"d":"99.00"},201.01,"<1","N/A","http://selleckchem.com/products/Cilnidipine.html","C27H28N2O7","free base","FRC-8653","COCCOC(=O)C1=C(C)NC(=C(C1C2=CC(=CC=C2)[N+]([O-])=O)C(=O)OC\\C=C\\C3=CC=CC=C3)C",3.686,5,1,12]
["S1315","Ki16425","h5","L4000-01","in 10mM DMSO","LPA Receptor","GPCR & G Protein","Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM in RH7777 cell lines, respectively, shows no activity at LPA4, LPA5, LPA6.",474.96,"355025-24-0",{"v":94,"d":"94.00"},197.91,"<1","N/A","http://selleckchem.com/products/Ki16425.html","C23H23ClN2O5S","free base","N/A","CC(OC(=O)NC1=C(ON=C1C)C2=CC=C(CSCCC(O)=O)C=C2)C3=C(Cl)C=CC=C3",5.043,5,1,10]
["S1324","Doxazosin Mesylate","a6","L4000-01","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Doxazosin, a quinazoline-derivative, selectively antagonizes postsynaptic α1-adrenergic receptors, used in the treatment of high blood pressure and urinary retention associated with benign prostatic hyperplasia.",547.58,"77883-43-3",{"v":15,"d":"15.00"},27.39,"<1","N/A","http://selleckchem.com/products/Doxazosin-mesylate.html","C23H25N5O5.CH4O3S","Mesylate","N/A","COC1=C(OC)C=C2C(=NC(=NC2=C1)N3CCN(CC3)C(=O)C4COC5=C(O4)C=CC=C5)N.C[S](O)(=O)=O",2.071,7,1,4]
["S1326","Edaravone","b6","L4000-01","in 10mM DMSO","Antioxidant","ER stress & UPR","Edaravone (MCI-186) is a novel potent free radical scavenger that has been clinically used to reduce the neuronal damage following ischemic stroke.",{"v":174.2,"d":"174.20"},"89-25-8",{"v":35,"d":"35.00"},200.92,"<1","N/A","http://selleckchem.com/products/Edaravone.html","C10H10N2O","free base","MCI-186","CC1=NN(C(=O)C1)C2=CC=CC=C2",1.123,2,0,1]
["S1328","Etodolac","c6","L4000-01","in 10mM DMSO","COX","Neuronal Signaling","Etodolac(AY-24236) is a nonsteroidal anti-inflammatory drug (NSAID) and a COX inhibitor, used for the treatment of inflammation and pain.",287.35,"41340-25-4",{"v":58,"d":"58.00"},201.84,"<1","N/A","http://selleckchem.com/products/Etodolac.html","C17H21NO3","free base","AY-24236","CCC1=CC=CC2=C1[NH]C3=C2CCOC3(CC)CC(O)=O",3.723,2,1,4]
["S1330","Felbamate","d6","L4000-01","in 10mM DMSO","NMDAR","Neuronal Signaling","Felbamate (Felbatol, ADD-03055,W-554) is an anticonvulsant drug used in the treatment of epilepsy; NMDAR antagonist.",238.24,"25451-15-4",{"v":48,"d":"48.00"},201.48,"<1","N/A","http://selleckchem.com/products/Felbamate.html","C11H14N2O4","free base","Felbatol, ADD-03055,W-554","NC(=O)OCC(COC(N)=O)C1=CC=CC=C1",0.984,4,2,7]
["S1332","Flumazenil (RO 15-1788)","e6","L4000-01","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Flumazenil (RO 15-1788) is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses.",303.29,"78755-81-4",{"v":5,"d":"5.00"},16.49,"<1","N/A","http://selleckchem.com/products/Flumazenil.html","C15H14FN3O3","free base","RO 15-1788","CCOC(=O)C1=C2CN(C)C(=O)C3=CC(=CC=C3[N]2C=N1)F",1.583,4,0,3]
["S1333","Fluoxetine (Lilly 110140) HCl","f6","L4000-01","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Fluoxetine HCl (Prozac, Sarafem,LY-110140) is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, used in the treatment of depression.",345.79,"56296-78-7",{"v":69,"d":"69.00"},199.54,{"v":4,"d":"4.00"},11.57,"http://selleckchem.com/products/Fluoxetine-hydrochloride.html","C17H18F3NO.HCl","Hydrochloride","Prozac, Sarafem,LY-110140","Cl.CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C2=CC=CC=C2",4.415,1,1,7]
["S1334","Flupirtine maleate","g6","L4000-01","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Flupirtine maleate is the salt form of Flupirtine, which is a centrally acting non-opioid analgesia, is a selective neuronal potassium channel opener that also has NMDA receptor antagonist properties.",420.39,"75507-68-5",{"v":84,"d":"84.00"},199.81,"<1","N/A","http://selleckchem.com/products/Flupirtine-maleate.html","C15H17FN4O2.C4H4O4","Maleate","N/A","CCOC(=O)NC1=C(N)N=C(NCC2=CC=C(F)C=C2)C=C1.OC(=O)\\C=C\\C(O)=O",{"v":2.76,"d":"2.760"},5,3,8]
["S1336","Fluvoxamine (DU-23000) maleate","h6","L4000-01","in 10mM DMSO","Serotonin Transporter","Neuronal Signaling","Fluvoxamine maleate (DU-23000, MK-264) is a selective serotonin (5-HT) reuptake inhibitor (SSRI), used in the treatment of obsessive-compulsive disorder.",434.41,"61718-82-9",{"v":87,"d":"87.00"},200.27,"<1","N/A","http://selleckchem.com/products/Fluvoxamine-maleate.html","C19H25F3N2O6","Maleate","MK-264,DU-23000 maleate","COCCCCC(=N\\OCCN)/C1=CC=C(C=C1)C(F)(F)F.OC(=O)\\C=C/C(O)=O",0.111,5,1,12]
["S1343","Ginkgolide B","a7","L4000-01","in 10mM DMSO","PAFR","GPCR & G Protein","Ginkgolide B (BN52021) is a PAFR antagonist with IC50 of 3.6 μM.",{"v":424.4,"d":"424.40"},"15291-77-7",{"v":85,"d":"85.00"},200.28,"<1","N/A","http://selleckchem.com/products/Ginkgolide-B.html","C20H24O10","free base","BN52021","CC1C(=O)OC2C(O)C34C5CC(C(C)(C)C)C36C(O)C(=O)OC6OC4(C(=O)O5)C12O",-0.854,7,2,1]
["S1351","Ivermectin (MK-933)","b7","L4000-01","in 10mM DMSO","AChR,Autophagy,Chloride Channel,COVID-19,HIV,Mitophagy,P2 Receptor","Transmembrane Transporters","Ivermectin (MK-933, IVM) is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug. Ivermectin (MK-933, IVM) is a specific positive allosteric effector of P2X4 and α7 nicotinic acetylcholine receptors (nAChRs). Ivermectin has potent antiviral activity towards both HIV-1 and dengue virus. Ivermectin induces autophagy through the AKT/mTOR signaling pathway and mitophagy.",875.09,"70288-86-7",{"v":100,"d":"100.00"},114.27,"<1","N/A","http://selleckchem.com/products/Ivermectin.html","C48H74O14","Free Base","MK-933","CCC(C)C1OC2(CCC1C)CC3CC(C\\C=C(C)\\C(OC4CC(OC)C(OC5CC(OC)C(O)C(C)O5)C(C)O4)C(C)\\C=C\\C=C\\6COC7C(O)C(=CC(C(=O)O3)C67O)C)O2",4.743,11,2,8]
["S1356","Levetiracetam (UCB-L059)","c7","L4000-01","in 10mM DMSO","AChR,Calcium Channel","Transmembrane Transporters","Levetiracetam (UCB-L059, SIB-S1) is an anticonvulsant medication used to treat epilepsy. Levetiracetam (UCB-L059, SIB-S1) is an agonist of muscarinic acetylcholine receptors (mAChR). Levetiracetam modulates the presynaptic P/Q-type voltage-dependent calcium (Ca2+) channel.",170.21,"102767-28-2",{"v":34,"d":"34.00"},199.75,{"v":34,"d":"34.00"},199.75,"http://selleckchem.com/products/Levetiracetam.html","C8H14N2O2","free base","UCB-L059, SIB-S1","CCC(N1CCCC1=O)C(N)=O",-0.304,2,1,3]
["S1357","Lidocaine","d7","L4000-01","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.",234.34,"137-58-6",{"v":47,"d":"47.00"},200.56,{"v":9,"d":"9.00"},38.41,"http://selleckchem.com/products/Lidocaine.html","C14H22N2O","Free Base","Alphacaine","CCN(CC)CC(=O)NC1=C(C)C=CC=C1C",2.626,1,1,5]
["S1358","Loratadine (SCH29851)","e7","L4000-01","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Loratadine (Alavert,Claritin,SCH29851) is a histamine H1 receptor antagonist, used to treat allergies. Also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.",382.88,"79794-75-5",{"v":17,"d":"17.00"},{"v":44.4,"d":"44.40"},"<1","N/A","http://selleckchem.com/products/Loratadine.html","C22H23ClN2O2","free base","Alavert,Claritin,SCH29851","CCOC(=O)N1CCC(CC1)=C2C3=C(CCC4=C2N=CC=C4)C=C(Cl)C=C3",{"v":5,"d":"5.000"},3,0,2]
["S1359","Losartan Potassium (DuP 753)","f7","L4000-01","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Losartan Potassium (DuP 753, MK 954) is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.",462.01,"124750-99-8",{"v":92,"d":"92.00"},199.13,{"v":92,"d":"92.00"},199.13,"http://selleckchem.com/products/losartan-potassium.html","C22H23ClKN6O","Potassium salt","MK 954,DuP 753","[KH].CCCCC1=NC(=C(CO)[N]1CC2=CC=C(C=C2)C3=C(C=CC=C3)C4=NN=N[NH]4)Cl",4.241,4,2,8]
["S1379","Isotretinoin","g7","L4000-01","in 10mM DMSO","Hydroxylase","Metabolism","Isotretinoin (13-cis retinoic acid) was developed to be used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more.",300.44,"4759-48-2",{"v":60,"d":"60.00"},199.71,"<1","N/A","http://selleckchem.com/products/Isotretinoin.html","C20H28O2","free base","13-cis retinoic acid","CC1=C(\\C=C\\C(C)=C\\C=C\\C(C)=C/C(O)=O)C(C)(C)CCC1",5.551,1,0,5]
["S1382","Mianserin HCl","h7","L4000-01","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Mianserin (Bolvidon, Norval, Tolvon,ORG GB-94 HCl,Mianserin hydrochloride) is an potent antagonist of H1 histamine receptor and 5-HT serotonin receptors, used for the treatment of depression.",300.83,"21535-47-7",{"v":60,"d":"60.00"},199.45,{"v":30,"d":"30.00"},99.72,"http://selleckchem.com/products/mianserin-hydrochloride.html","C18H20N2.HCl","Hydrochloride","Bolvidon, Norval, Tolvon,ORG GB-94 HCl,Mianserin hydrochloride","Cl.CN1CCN2C(C1)C3=C(CC4=C2C=CC=C4)C=CC=C3",4.088,0,0,0]
["S1385","Mosapride Citrate","a8","L4000-01","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Mosapride Citrate (TAK-370, AS-4370, Gasmotin) is a gastroprokinetic agent that acts as a selective 5HT4 agonist.",614.02,"112885-42-4",{"v":90,"d":"90.00"},146.58,"<1","N/A","http://selleckchem.com/products/Mosapride-citrate.html","C21H25ClFN3O3.C6H8O7","Citrate","TAK-370, AS-4370, Gasmotin","CCOC1=CC(=C(Cl)C=C1C(=O)NCC2CN(CCO2)CC3=CC=C(F)C=C3)N.OC(=O)CC(O)(CC(O)=O)C(O)=O",-1.422,6,2,12]
["S1387","Naftopidil DiHCl","b8","L4000-01","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Naftopidil DiHCl (Flivas, KT-611, Avishot,BM-15275) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.",465.41,"57149-08-3",{"v":41,"d":"41.00"},88.09,"<1","N/A","http://selleckchem.com/products/Naftopidil-Dihydrochloride.html","C24H28N2O3.2HCl","Dihydrochloride","Flivas, KT-611, Avishot,BM-15275","Cl.Cl.COC1=CC=CC=C1N2CCN(CC2)CC(O)COC3=C4C=CC=CC4=CC=C3",4.726,2,1,7]
["S1390","Ondansetron HCl","c8","L4000-01","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Ondansetron HCl (Ondemet, Emeset, Emetron,GR 38032F,SN 307) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation therapy.",329.82,"99614-01-4",{"v":66,"d":"66.00"},200.11,{"v":24,"d":"24.00"},72.77,"http://selleckchem.com/products/Ondansetron-hydrochloride.html","C18H19N3O.HCl","Hydrochloride","Ondemet, Emeset, Emetron,GR 38032F,SN 307","Cl.C[N]1C2=C(C(=O)C(CC2)C[N]3C=CN=C3C)C4=CC=CC=C14",3.016,2,0,2]
["S1391","Oxcarbazepine","d8","L4000-01","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Oxcarbazepine (GP47680) inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM.",252.27,"28721-07-5",{"v":7,"d":"7.00"},27.75,"<1","N/A","http://selleckchem.com/products/Oxcarbazepine.html","C15H12N2O2","free base","GP47680","NC(=O)N1C2=C(CC(=O)C3=C1C=CC=C3)C=CC=C2",2.131,2,1,0]
["S1394","Pizotifen Malate","e8","L4000-01","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Pizotifen Malate (Sandomigran, pizotyline,BC-105) is a benzocycloheptane based agent used for recurrent migraine headaches.",429.53,"5189-11-7",{"v":21,"d":"21.00"},48.89,"<1","N/A","http://selleckchem.com/products/Pizotifen-malate.html","C19H21NS.C4H6O5","Malate","Sandomigran, pizotyline,BC-105","CN1CCC(CC1)=C2C3=C(CCC4=C2C=CC=C4)SC=C3.OC(CC(O)=O)C(O)=O",0.292,2,1,3]
["S1396","Resveratrol (SRT501)","f8","L4000-01","in 10mM DMSO","AMPK,Apoptosis related,Autophagy,COX,ERK,IκB/IKK,JNK,Lipoxygenase,Mitophagy,Sirtuin,Src,STAT","Autophagy","Resveratrol (SRT501, trans-Resveratrol) has a wide spectrum of targets including cyclooxygenases(i.e. COX, IC50=1.1 μM), lipooxygenases（LOX, IC50=2.7 μM）, kinases, sirtuins and other proteins. It has anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects. Resveratrol induces mitophagy/autophagy and autophagy-dependent apoptosis.",228.24,"501-36-0",{"v":45,"d":"45.00"},197.16,"<1","N/A","http://selleckchem.com/products/Resveratrol.html","C14H12O3","free base","trans-Resveratrol,SRT501","OC1=CC=C(C=C1)\\C=C\\C2=CC(=CC(=C2)O)O",{"v":3.09,"d":"3.090"},0,3,2]
["S1397","Rocuronium Bromide","g8","L4000-01","in 10mM DMSO","AChR","Neuronal Signaling","Rocuronium Bromide (ORG 9426) is a competitive AchR antagonist, used in modern anaesthesia.",609.68,"119302-91-9",{"v":122,"d":"122.00"},{"v":200.1,"d":"200.10"},{"v":122,"d":"122.00"},{"v":200.1,"d":"200.10"},"http://selleckchem.com/products/Rocuronium-bromide.html","C32H53N2O4.Br","Bromide","ORG 9426","[Br-].CC(=O)OC1C(CC2C3CCC4CC(O)C(CC4(C)C3CCC12C)N5CCOCC5)[N+]6(CCCC6)CC=C",0.282,3,1,6]
["S1404","Trilostane","h8","L4000-01","in 10mM DMSO","Dehydrogenase","Metabolism","Trilostane (WIN 24540) is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing’s syndrome.",329.43,"13647-35-3",{"v":65,"d":"65.00"},197.31,"<1","N/A","http://selleckchem.com/products/Trilostane.html","C20H27NO3","free base","WIN 24540","CC12CCC3C(CCC45OC4C(=C(CC35C)C#N)O)C1CCC2O",2.434,1,2,0]
["S1405","Vecuronium Bromide","a9","L4000-01","in 10mM DMSO","AChR","Neuronal Signaling","Vecuronium Bromide (ORG NC45) is a non-depolarizing neuromuscular blocking agent, used for skeletal muscle relaxation during surgery.",637.73,"50700-72-6",{"v":100,"d":"100.00"},156.81,{"v":4,"d":"4.00"},6.27,"http://selleckchem.com/products/Vecuronium-Bromide.html","C34H57N2O4.Br","Bromide","ORG NC45","[Br-].CC(=O)OC1CC2CCC3C(CCC4(C)C3CC(C4OC(C)=O)[N+]5(C)CCCCC5)C2(C)CC1N6CCCCC6",{"v":1.73,"d":"1.730"},4,0,6]
["S1407","Bimatoprost","b9","L4000-01","in 10mM DMSO","Prostaglandin Receptor","GPCR & G Protein","Bimatoprost(AGN 192024) is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.",415.57,"155206-00-1",{"v":36,"d":"36.00"},86.63,"<1","N/A","http://selleckchem.com/products/Bimatoprost.html","C25H37NO4","free base","AGN 192024","CCNC(=O)CCC\\C=C/CC1C(O)CC(O)C1/C=C/C(O)CCC2=CC=CC=C2",{"v":3.03,"d":"3.030"},1,4,12]
["S1409","Alfuzosin HCl","c9","L4000-01","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Alfuzosin HCI(SL 77499 HCl)  is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH).",425.91,"81403-68-1",{"v":85,"d":"85.00"},199.57,{"v":85,"d":"85.00"},199.57,"http://selleckchem.com/products/Alfuzosin-hydrochloride.html","C19H27N5O4.HCl","Hydrochloride","SL 77499 HCl","Cl.COC1=C(OC)C=C2C(=NC(=NC2=C1)N(C)CCCNC(=O)C3CCCO3)N",{"v":1.8,"d":"1.800"},6,2,8]
["S1415","Clopidogrel (SR-25990C) Bisulfate","d9","L4000-01","in 10mM DMSO","P2 Receptor","Neuronal Signaling","Clopidogrel Bisulfate (SR-25990C, Clopidogrel hydrogen sulfate, Iscover, Plavix) is an oral, thienopyridine class antiplatelet agent.",{"v":419.9,"d":"419.90"},"120202-66-6",{"v":83,"d":"83.00"},197.67,{"v":78,"d":"78.00"},185.76,"http://selleckchem.com/products/Clopidogrel-bisulfate.html","C16H16ClNO2S.H2SO4","Bisulfate","SR-25990C, Clopidogrel hydrogen sulfate, Iscover, Plavix","COC(=O)C(N1CCC2=C(C1)C=CS2)C3=C(Cl)C=CC=C3.O[S](O)(=O)=O",3.128,2,0,4]
["S1425","Ranolazine 2HCl","e9","L4000-01","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Ranolazine 2HCl (RS-43285,RS 43285-193,Ranexa, renolazine,Ranolazine dihydrochloride) is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina.",500.46,"95635-56-6",{"v":100,"d":"100.00"},199.82,{"v":100,"d":"100.00"},199.82,"http://selleckchem.com/products/Ranolazine-dihydrochloride.html","C24H33N3O4.2HCl","Dihydrochloride","RS-43285,RS 43285-193,Ranexa, renolazine,Ranolazine dihydrochloride","Cl.Cl.COC1=CC=CC=C1OCC(O)CN2CCN(CC2)CC(=O)NC3=C(C)C=CC=C3C",3.755,3,2,9]
["S1432","Sumatriptan Succinate","f9","L4000-01","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Sumatriptan Succinate (GR 43175) is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches.",413.49,"103628-48-4",{"v":83,"d":"83.00"},200.73,{"v":83,"d":"83.00"},200.73,"http://selleckchem.com/products/Sumatriptan-succinate.html","C14H21N3O2S.C4H6O4","Succinate","GR 43175","CN[S](=O)(=O)CC1=CC=C2[NH]C=C(CCN(C)C)C2=C1.OC(=O)CCC(O)=O",-1.958,4,2,9]
["S1435","Tamsulosin hydrochloride","g9","L4000-01","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Tamsulosin (Flomax) hydrochloride is an antagonist of alpha1A adrenoceptors in the prostate.",444.97,"106463-17-6",{"v":89,"d":"89.00"},200.01,"<1","N/A","https://www.selleckchem.com/products/Tamsulosin-hydrochloride.html","C20H28N2O5S.HCl","HCl","Flomax hydrochloride","CCOC1=C(OCCNC(C)CC2=CC=C(OC)C(=C2)[S](N)(=O)=O)C=CC=C1",2.719,5,2,11]
["S1437","Tizanidine HCl","h9","L4000-01","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Tizanidine HCl (DS 103-282) is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.",290.17,"64461-82-1",{"v":10,"d":"10.00"},34.46,{"v":15,"d":"15.00"},51.69,"http://selleckchem.com/products/Tizanidine-hydrochloride.html","C9H8ClN5S.HCl","Hydrochloride","DS 103-282","Cl.ClC1=C(NC2=NCCN2)C3=NSN=C3C=C1",2.199,3,2,2]
["S1438","Topiramate","a10","L4000-01","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Topiramate (MCN 4853, RWJ 17021) is a mutil-targeted inhibitor, including voltage-gated sodium channel and calcium channel, AMPA/kainate receptor and carbonic anhydrase, used to treat epilepsy.",339.36,"97240-79-4",{"v":68,"d":"68.00"},200.38,"<1","N/A","http://selleckchem.com/products/Topiramate.html","C12H21NO8S","free base","MCN 4853, RWJ 17021","CC1(C)OC2COC3(CO[S](N)(=O)=O)OC(C)(C)OC3C2O1",-1.932,6,1,3]
["S1441","Venlafaxine HCl","b10","L4000-01","in 10mM DMSO","Serotonin Transporter","Neuronal Signaling","Venlafaxine HCl(Wy 453 HCl) is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.",313.86,"99300-78-4",{"v":55.5,"d":"55.50"},176.83,{"v":55.5,"d":"55.50"},176.83,"http://selleckchem.com/products/Venlafaxine-hydrochloride.html","C17H27NO2.HCl","Hydrochloride","Wy 453 HCl","Cl.COC1=CC=C(C=C1)C(CN(C)C)C2(O)CCCCC2",3.404,1,0,5]
["S1444","Ziprasidone HCl","c10","L4000-01","in 10mM DMSO","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Ziprasidone HCl (CP-88059) is a novel and potent dopamine and serotonin (5-HT) receptor antagonist, used in the treatment of schizophrenia and bipolar disorder.",{"v":449.4,"d":"449.40"},"122883-93-6",{"v":90,"d":"90.00"},200.27,"<1","N/A","http://selleckchem.com/products/Ziprasidone-hydrochloride.html","C21H21ClN4OS.HCl","Hydrochloride","CP-88059","Cl.ClC1=CC2=C(CC(=O)N2)C=C1CCN3CCN(CC3)C4=NSC5=C4C=CC=C5",4.641,2,1,4]
["S1445","Zonisamide","d10","L4000-01","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Zonisamide (Zonegran,CI-912,AD 810) is a voltage-dependent sodium channel and T-type calcium channel blocker, used as an antiepileptic drug.",212.23,"68291-97-4",{"v":42,"d":"42.00"},{"v":197.9,"d":"197.90"},"<1","N/A","http://selleckchem.com/products/Zonisamide.html","C8H8N2O3S","free base","Zonegran,CI-912,AD 810","N[S](=O)(=O)CC1=NOC2=CC=CC=C12",0.411,4,1,2]
["S1455","Cilomilast","e10","L4000-01","in 10mM DMSO","PDE","Metabolism","Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.",343.42,"153259-65-5",{"v":69,"d":"69.00"},200.92,"<1","N/A","http://selleckchem.com/products/Cilomilast(SB-207499).html","C20H25NO4","free base","SB-207499","COC1=C(OC2CCCC2)C=C(C=C1)C3(CCC(CC3)C(O)=O)C#N",4.174,3,0,5]
["S1458","Neflamapimod (VX-745)","f10","L4000-01","in 10mM DMSO","p38 MAPK","MAPK","Neflamapimod (VX-745) is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ.",436.26,"209410-46-8",{"v":15,"d":"15.00"},34.38,"<1","N/A","http://selleckchem.com/products/VX-745.html","C19H9Cl2F2N3OS","free base","N/A","FC1=CC(=C(SC2=NN3C=NC(=O)C(=C3C=C2)C4=C(Cl)C=CC=C4Cl)C=C1)F",5.342,3,0,3]
["S1460","SP600125","g10","L4000-01","in 10mM DMSO","Apoptosis related,Aurora Kinase,Autophagy,FLT3,JNK,Serine/threonin kinase,Trk receptor","MAPK","SP600125 (Nsc75890) is a broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 40 nM, 40 nM and 90 nM in cell-free assays, respectively; 10-fold greater selectivity against MKK4, 25-fold greater selectivity against MKK3, MKK6, PKB, and PKCα, and 100-fold selectivity against ERK2, p38, Chk1, EGFR etc. SP600125 is also a broad‐spectrum inhibitor of serine/threonine kinases including Aurora kinase A，FLT3 and TRKA with of IC50 of 60 nM, 90 nM and 70 nM. SP600125 inhibits autophagy and activates apoptosis.",220.23,"129-56-6",{"v":44,"d":"44.00"},199.79,"<1","N/A","http://selleckchem.com/products/SP600125.html","C14H8N2O","free base","Nsc75890","O=C1C2=C(C=CC=C2)C3=N[NH]C4=CC=CC1=C34",2.994,2,1,0]
["S1472","Safinamide Mesylate","h10","L4000-01","in 10mM DMSO","MAO","Metabolism","Safinamide Mesylate (PNU-151774E, FCE28073) is mesylate salt of Safinamide, selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A. Phase 3.",398.45,"202825-46-5",{"v":80,"d":"80.00"},200.78,{"v":80,"d":"80.00"},200.78,"http://selleckchem.com/products/Safinamide-mesilate.html","C17H19FN2O2.CH4O3S","Mesylate","PNU-151774E,FCE28073","CC(NCC1=CC=C(OCC2=CC(=CC=C2)F)C=C1)C(N)=O.C[S](O)(=O)=O",2.064,2,2,7]
["S1481","Zosuquidar (LY335979) 3HCl","a11","L4000-01","in 10mM DMSO","P-gp","Transmembrane Transporters","Zosuquidar 3HCl (LY335979, RS 33295-198, D06387) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of 60 nM in a cell-free assay. Phase 3.",636.99,"167465-36-3",{"v":100,"d":"100.00"},156.99,{"v":23,"d":"23.00"},36.11,"http://selleckchem.com/products/LY335979.html","C32H31F2N3O2.3HCl","Trihydrochlorid","RS 33295-198 (D06387) 3HCl","Cl.Cl.Cl.OC(COC1=CC=CC2=C1C=CC=N2)CN3CCN(CC3)C4C5=C(C=CC=C5)C6C(C7=C4C=CC=C7)C6(F)F",5.845,2,1,6]
["S1483","Iloperidone","b11","L4000-01","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Iloperidone (HP873) is a dopamine (D2)/serotonin (5-HT2) receptor antagonist, used for the treatment of schizophrenia.",426.48,"133454-47-4",{"v":27,"d":"27.00"},63.31,"<1","N/A","http://selleckchem.com/products/Iloperidone(Fanapt).html","C24H27FN2O4","free base","HP873","COC1=C(OCCCN2CCC(CC2)C3=NOC4=C3C=CC(=C4)F)C=CC(=C1)C(C)=O",4.016,5,0,8]
["S1488","Naratriptan HCl","c11","L4000-01","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Naratriptan HCl is a triptan agent that is used for the treatment of migraine headaches.",371.93,"143388-64-1",{"v":74,"d":"74.00"},198.96,{"v":22,"d":"22.00"},59.15,"http://selleckchem.com/products/Naratriptan(Amerge).html","C17H25N3O2S.HCl","Hydrochloride","N/A","Cl.CN[S](=O)(=O)CCC1=CC=C2[NH]C=C(C3CCN(C)CC3)C2=C1",2.435,2,2,5]
["S1500","Betamethasone","d11","L4000-01","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Betamethasone (NSC-39470, SCH-4831) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.",392.46,"378-44-9",{"v":79,"d":"79.00"},201.29,"<1","N/A","http://selleckchem.com/products/Betamethasone-(Celestone).html","C22H29FO5","Free Base","NSC-39470, SCH-4831","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO",1.708,2,2,2]
["S1504","Dyphylline","e11","L4000-01","in 10mM DMSO","PDE","Metabolism","Dyphylline (Diprophylline) is a xanthine derivative with bronchodilator and vasodilator effects.",254.24,"479-18-5",{"v":51,"d":"51.00"},{"v":200.6,"d":"200.60"},{"v":51,"d":"51.00"},{"v":200.6,"d":"200.60"},"http://selleckchem.com/products/Dyphylline(Dilor).html","C10H14N4O4","free base","Diprophylline","CN1C(=O)N(C)C2=C([N](CC(O)CO)C=N2)C1=O",-1.151,3,2,3]
["S1508","Alprostadil","f11","L4000-01","in 10mM DMSO","PGES","Endocrinology & Hormones","Alprostadil (Prostaglandin-E1, PGE1, Edex, Muse, Liprostin) is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It is a Prostaglandin Analog and Prostaglandin E1 Agonist.",354.48,"745-65-3",{"v":71,"d":"71.00"},200.29,"<1","N/A","http://selleckchem.com/products/Alprostadil(Caverject).html","C20H34O5","free base","Prostaglandin-E1, PGE1, Edex, Muse, Liprostin","CCCCCC(O)/C=C/C1C(O)CC(=O)C1CCCCCCC(O)=O",3.644,2,2,13]
["S1512","Tadalafil (IC351)","g11","L4000-01","in 10mM DMSO","PDE","Metabolism","Tadalafil (IC351) is a PDE-5 inhibitor with IC50 of 1.8 nM in a cell-free assay. Tadalafil is at least 9000 times more selective for PDE5 than most of the other families of PDEs, with the exception of PDE11. It can partial inhibits PDE11",{"v":389.4,"d":"389.40"},"171596-29-5",{"v":78,"d":"78.00"},200.31,"<1","N/A","http://selleckchem.com/products/Tadalafil(Cialis).html","C22H19N3O4","free base","IC351","CN1CC(=O)N2C(CC3=C([NH]C4=C3C=CC=C4)C2C5=CC=C6OCOC6=C5)C1=O",2.183,4,1,1]
["S1528","LY2811376","h11","L4000-01","in 10mM DMSO","BACE,Beta Amyloid","Proteases","LY2811376 is the first orally available non-peptidic β-secretase(BACE1) inhibitor with IC50 of 239 nM-249 nM, that act to decrease Aβ secretion with EC50 of 300 nM, demonstrated to have 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases including cathepsin D, pepsin, or renin. Phase 1.",320.36,"1194044-20-6",{"v":16,"d":"16.00"},49.94,"<1","N/A","http://selleckchem.com/products/LY2811376.html","C15H14F2N4S","free base","N/A","CC1(CCSC(=N1)N)C2=CC(=C(F)C=C2F)C3=CN=CN=C3",2.478,3,1,2]
["S1534","Org 27569","a2","L4000-02","in 10mM DMSO","Cannabinoid Receptor","GPCR & G Protein","Org 27569 is an allosteric modulator of cannabinoid CB1 receptor, induces a CB1 receptor state that is characterized by enhanced agonist affinity and decreased inverse agonist affinity.",409.95,"868273-06-7",{"v":82,"d":"82.00"},200.02,"<1","N/A","http://selleckchem.com/products/Org-27569.html","C24H28ClN3O","free base","N/A","CCC1=C([NH]C2=CC=C(Cl)C=C12)C(=O)NCCC3=CC=C(C=C3)N4CCCCC4",6.213,1,2,6]
["S1541","Selisistat (EX 527)","b2","L4000-02","in 10mM DMSO","Sirtuin","Epigenetics","Selisistat (EX 527, SEN0014196) is a potent and selective SIRT1 inhibitor with IC50 of 38 nM in a cell-free assay, exhibits >200-fold selectivity against SIRT2 and SIRT3. Phase 2.",248.71,"49843-98-3",{"v":49,"d":"49.00"},197.02,"<1","N/A","http://selleckchem.com/products/EX-527.html","C13H13ClN2O","free base","SEN0014196","NC(=O)C1CCCC2=C1[NH]C3=C2C=C(Cl)C=C3",3.149,1,2,1]
["S1544","AM1241","c2","L4000-02","in 10mM DMSO","Cannabinoid Receptor","GPCR & G Protein","AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor.",503.33,"444912-48-5",{"v":101,"d":"101.00"},200.66,"<1","N/A","http://selleckchem.com/products/AM-1241.html","C22H22IN3O3","free base","N/A","CN1CCCCC1C[N]2C=C(C(=O)C3=CC(=CC=C3I)[N+]([O-])=O)C4=C2C=CC=C4",{"v":5.29,"d":"5.290"},1,0,5]
["S1545","SB408124","d2","L4000-02","in 10mM DMSO","OX Receptor","GPCR & G Protein","SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.",356.37,"288150-92-5",{"v":36,"d":"36.00"},101.02,"<1","N/A","http://selleckchem.com/products/sb-408124.html","C19H18F2N4O","free base","N/A","CN(C)C1=CC=C(NC(=O)NC2=CC(=NC3=C(F)C=C(F)C=C23)C)C=C1",3.565,2,2,3]
["S1549","Nebivolol hydrochloride (R-65824)","e2","L4000-02","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Nebivolol HCl (R-65824) selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM.",{"v":441.9,"d":"441.90"},"152520-56-4",{"v":88,"d":"88.00"},199.14,"<1","N/A","http://selleckchem.com/products/Nebivolol(Bystolic).html","C22H25F2NO4.HCl","Hydrochloride","R-65824 hydrochloride","Cl.OC(CNCC(O)C1CCC2=C(O1)C=CC(=C2)F)C3CCC4=CC(=CC=C4O3)F",3.939,2,3,6]
["S1550","Pimobendan","f2","L4000-02","in 10mM DMSO","PDE","Metabolism","Pimobendan (UD-CG 115 BS) is a selective inhibitor of PDE3 with IC50 of 0.32 μM.",334.37,"74150-27-9",{"v":67,"d":"67.00"},200.38,"<1","N/A","http://selleckchem.com/products/Pimobendan(Vetmedin).html","C19H18N4O2","free base","UD-CG 115 BS","COC1=CC=C(C=C1)C2=NC3=CC(=CC=C3[NH]2)C4=NNC(=O)CC4C",2.936,4,2,3]
["S1573","Fasudil (HA-1077) HCl","g2","L4000-02","in 10mM DMSO","Autophagy,Calcium Channel,MLCK,PKA,PKC,PKG,Rho,ROCK","Cell Cycle","Fasudil (HA-1077, AT-877), a potent and selective inhibitor of Rho kinase, displays less potent inhibiton over PKA, PKG, PKC and MLCK with Ki of 1.6, 1.6, 3.3, and 36 μM in cell-free assays, respectively. Fasudil is also a calcium channel blocker.",327.83,"105628-07-7",{"v":5,"d":"5.00"},15.25,{"v":65,"d":"65.00"},198.27,"http://selleckchem.com/products/Fasudil-HCl(HA-1077).html","C14H17N3O2S.HCl","Hydrochloride","AT-877,HA-1077 HCl","Cl.O=[S](=O)(N1CCCNCC1)C2=C3C=CN=CC3=CC=C2",{"v":0.57,"d":"0.570"},3,1,2]
["S1576","Sulfasalazine (NSC 667219)","h2","L4000-02","in 10mM DMSO","Apoptosis related,Autophagy,COX,Ferroptosis,Immunology & Inflammation related,NF-κB,TGF-beta/Smad","Immunology & Inflammation","Sulfasalazine (NSC 667219, Azulfidine, Salazopyrin, Sulphasalazine) is a sulfa derivative of mesalazine, used as an anti-inflammatory agent to treat bowel disease and rheumatoid arthritis. Sulfasalazine is a potent and specific inhibitor of nuclear factor kappa B (NF-κB), TGF-β and COX-2. Sulfasalazine induces ferroptosis, apoptosis and autophagy.",398.39,"599-79-1",{"v":80,"d":"80.00"},200.81,"<1","N/A","http://selleckchem.com/products/Sulfasalazine(Azulfidine).html","C18H14N4O5S","free base","Azulfidine, Salazopyrin, Sulphasalazine, NSC 667219","OC(=O)C1=C(O)C=CC(=C1)N=NC2=CC=C(C=C2)[S](=O)(=O)NC3=CC=CC=N3",3.463,6,2,6]
["S1578","Candesartan (CV-11974)","a3","L4000-02","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Candesartan (CV-11974) is an angiotensin II receptor antagonist with IC50 of 0.26 nM.",440.45,"139481-59-7",{"v":88,"d":"88.00"},{"v":199.8,"d":"199.80"},"<1","N/A","http://selleckchem.com/products/Candesartan(Atacand).html","C24H20N6O3","free base","CV-11974","CCOC1=NC2=C([N]1CC3=CC=C(C=C3)C4=CC=CC=C4C5=N[NH]N=N5)C(=CC=C2)C(O)=O",4.626,6,1,7]
["S1590","TWS119","b3","L4000-02","in 10mM DMSO","Autophagy,GSK-3","PI3K/Akt/mTOR","TWS119 is a GSK-3β inhibitor with IC50 of 30 nM in a cell-free assay; capable of inducing neuronal differentiation and may be useful to stem cell biology. GSK-3β inhibition triggers autophagy.",318.33,"601514-19-6",{"v":64,"d":"64.00"},201.05,"<1","N/A","http://selleckchem.com/products/TWS119.html","C18H14N4O2","free base","N/A","NC1=CC(=CC=C1)C2=CC3=C([NH]2)N=CN=C3OC4=CC=CC(=C4)O",3.464,3,3,3]
["S1594","Semagacestat (LY450139)","c3","L4000-02","in 10mM DMSO","Beta Amyloid,Notch,Secretase","Proteases","Semagacestat (LY450139) is a γ-secretase blocker for Aβ42, Aβ40 and Aβ38 with IC50 of 10.9 nM, 12.1 nM and 12.0 nM, also inhibits Notch signaling with IC50 of 14.1 nM in H4 human glioma cell. Phase 3.",361.44,"425386-60-3",{"v":72,"d":"72.00"},{"v":199.2,"d":"199.20"},"<1","N/A","http://selleckchem.com/products/Semagacestat(LY450139).html","C19H27N3O4","free base","N/A","CC(C)C(O)C(=O)NC(C)C(=O)NC1C(=O)N(C)CCC2=C1C=CC=C2",0.632,3,3,5]
["S1601","Reserpine","d3","L4000-02","in 10mM DMSO","VMAT","Transmembrane Transporters","Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug. Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).",608.68,"50-55-5",{"v":13,"d":"13.00"},21.36,"<1","N/A","http://selleckchem.com/products/Reserpine.html","C33H40N2O9","free base","N/A","COC1C(CC2CN3CCC4=C([NH]C5=C4C=CC(=C5)OC)C3CC2C1C(=O)OC)OC(=O)C6=CC(=C(OC)C(=C6)OC)OC",4.242,9,1,10]
["S1603","Furosemide (NSC 269420)","e3","L4000-02","in 10mM DMSO","NKCC","Transmembrane Transporters","Furosemide (NSC 269420) is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used in the treatment of congestive heart failure and edema.",330.74,"54-31-9",{"v":66,"d":"66.00"},199.55,"<1","N/A","http://selleckchem.com/products/Furosemide(Lasix).html","C12H11ClN2O5S","free base","NSC 269420","N[S](=O)(=O)C1=C(Cl)C=C(NCC2=CC=CO2)C(=C1)C(O)=O",1.403,4,2,5]
["S1604","Olmesartan Medoxomil","f3","L4000-02","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Olmesartan Medoxomil (CS-866,RNH-6270) is a selective angiotensin II type 1 (AT(1)) receptor antagonist, used in the treatment of high blood pressure.",558.59,"144689-63-4",{"v":89,"d":"89.00"},159.33,"<1","N/A","http://selleckchem.com/products/olmesartan-medoxomil-Benicar.html","C29H30N6O6","free base","CS-866,RNH-6270","CCCC1=NC(=C([N]1CC2=CC=C(C=C2)C3=CC=CC=C3C4=N[NH]N=N4)C(=O)OCC5=C(C)OC(=O)O5)C(C)(C)O",4.814,9,1,11]
["S1607","Rizatriptan Benzoate","g3","L4000-02","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Rizatriptan Benzoate (MK-462) is an agonist at serotonin 5-HT1B and 5-HT1D receptors, used to treat acute migraine attacks.",391.47,"145202-66-0",{"v":20,"d":"20.00"},51.09,{"v":46,"d":"46.00"},117.51,"http://selleckchem.com/products/Rizatriptan-Benzoate(Maxalt).html","C22H25N5O2","Benzoate","MK-462 Benzoate","CN(C)CCC1=C[NH]C2=C1C=C(C[N]3C=NC=N3)C=C2.OC(=O)C4=CC=CC=C4",0.492,3,1,6]
["S1608","Pyridostigmine Bromide","h3","L4000-02","in 10mM DMSO","AChR","Neuronal Signaling","Pyridostigmine Bromide is a parasympathomimetic and a reversible cholinesterase inhibitor.",261.12,"101-26-8",{"v":52,"d":"52.00"},199.14,{"v":52,"d":"52.00"},199.14,"http://selleckchem.com/products/Pyridostigmine-Bromide(Mestinon).html","C9H13BrN2O2","Bromide","N/A","[Br-].CN(C)C(=O)OC1=C[N+](=CC=C1)C",-1.014,2,0,2]
["S1613","Silodosin","a4","L4000-02","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Silodosin (KAD 3213, KMD 3213) is a highly selective α1A-adrenoceptor antagonist, used in treatment of benign prostatic hyperplasia.",495.53,"160970-54-7",{"v":99,"d":"99.00"},199.79,"<1","N/A","http://selleckchem.com/products/Silodosin(Rapaflo).html","C25H32F3N3O4","free base","KAD 3213, KMD 3213","CC(CC1=CC2=C(N(CCCO)CC2)C(=C1)C(N)=O)NCCOC3=CC=CC=C3OCC(F)(F)F",3.451,3,3,14]
["S1614","Riluzole (PK 26124)","b4","L4000-02","in 10mM DMSO","GluR,Sodium Channel","Transmembrane Transporters","Riluzole (PK 26124, RP-54274) is a glutamate release inhibitor with neuroprotective, anticonvulsant, anxiolytic and anesthetic qualities.",{"v":234.2,"d":"234.20"},"1744-22-5",{"v":46,"d":"46.00"},196.41,"<1","N/A","http://selleckchem.com/products/Riluzole(Rilutek).html","C8H5F3N2OS","free base","RP-54274, PK 26124","NC1=NC2=C(S1)C=C(OC(F)(F)F)C=C2",3.828,2,1,2]
["S1619","Prilocaine","c4","L4000-02","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Prilocaine (NSC 40027) is a local anesthetic of the amino amide type. It acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation.",220.31,"721-50-6",{"v":44,"d":"44.00"},199.72,"<1","N/A","http://selleckchem.com/products/Prilocaine.html","C13H20N2O","free base","NSC 40027","CCCNC(C)C(=O)NC1=C(C)C=CC=C1",2.263,1,2,5]
["S1622","Prednisone (NSC-10023)","d4","L4000-02","in 10mM DMSO","Glucocorticoid Receptor,Immunology & Inflammation related","Endocrinology & Hormones","Prednisone (NSC-10023, Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.",358.43,"53-03-2",{"v":71,"d":"71.00"},198.09,"<1","N/A","http://selleckchem.com/products/Prednisone.html","C21H26O5","free base","Adasone,NSC-10023","CC12CC(=O)C3C(CCC4=CC(=O)C=CC34C)C1CCC2(O)C(=O)CO",1.217,3,1,2]
["S1626","Naproxen Sodium","e4","L4000-02","in 10mM DMSO","COX","Neuronal Signaling","Naproxen Sodium (RS-3650) is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively.",252.24,"26159-34-2",{"v":3,"d":"3.00"},11.89,{"v":50,"d":"50.00"},198.22,"http://selleckchem.com/products/Naproxen-Sodium(Aleve).html","C14H13NaO3","Sodium Salt","RS-3650","[Na+].COC1=CC=C2C=C(C=CC2=C1)C(C)C([O-])=O",1.375,1,0,3]
["S1628","Triamcinolone Acetonide","f4","L4000-02","in 10mM DMSO","Glucocorticoid Receptor","Metabolism","Triamcinolone acetonide is a synthetic glucocorticoid, used in the symptomatic treatment of inflammation.",{"v":434.5,"d":"434.50"},"76-25-5",{"v":87,"d":"87.00"},200.23,"<1","N/A","http://selleckchem.com/products/Triamcinolone-Acetonide.html","C24H31FO6","free base","N/A","CC1(C)OC2CC3C4CCC5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(O1)C(=O)CO",1.157,4,2,2]
["S1638","Ibuprofen (NSC 256857)","g4","L4000-02","in 10mM DMSO","COX","Neuronal Signaling","Ibuprofen (NSC 256857, Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively.",206.28,"15687-27-1",{"v":41,"d":"41.00"},198.76,"<1","N/A","http://selleckchem.com/products/Ibuprofen(Advil).html","C13H18O2","free base","Dolgesic,NSC 256857","CC(C)CC1=CC=C(C=C1)C(C)C(O)=O",3.607,1,0,4]
["S1645","Ketoprofen","h4","L4000-02","in 10mM DMSO","COX","Neuronal Signaling","Ketoprofen (RP-19583) is a dual COX1/2 inhibitor, used as a nonsteroidal anti-inflammatory drug to treat arthritis-related inflammatory pains.",254.28,"22071-15-4",{"v":51,"d":"51.00"},200.57,"<1","N/A","http://selleckchem.com/products/Ketoprofen(Actron).html","C16H14O3","free base","RP-19583","CC(C(O)=O)C1=CC(=CC=C1)C(=O)C2=CC=CC=C2",3.361,2,0,4]
["S1646","Ketorolac","a5","L4000-02","in 10mM DMSO","COX","Neuronal Signaling","Ketorolac is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively.",255.27,"74103-06-3",{"v":75,"d":"75.00"},293.81,"<1","N/A","http://selleckchem.com/products/Ketorolac-Tromethamine(Toradol).html","C15H13N1O3","free base","N/A","OC(=O)C1CC[N]2C1=CC=C2C(=O)C3=CC=CC=C3",2.832,2,0,3]
["S1647","Adenosine","b5","L4000-02","in 10mM DMSO","Adenosine Receptor,Nucleoside Analog/Antimetabolite","GPCR & G Protein","Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond.",267.24,"58-61-7",{"v":12,"d":"12.00"},{"v":44.9,"d":"44.90"},"<1","N/A","http://selleckchem.com/products/Adenosine(Adenocard).html","C10H13N5O4","free base","N/A","NC1=NC=NC2=C1N=C[N]2C3OC(CO)C(O)C3O",-1.881,4,4,2]
["S1649","Zolmitriptan","c5","L4000-02","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Zolmitriptan(BW-311C90) is a novel and highly selective 5-HT(1B/1D) receptor agonist, used in the treatment of acute migraines.",287.36,"139264-17-8",{"v":58,"d":"58.00"},201.84,"<1","N/A","http://selleckchem.com/products/Zolmitriptan(Zomig).html","C16H21N3O2","free base","BW-311C90","CN(C)CCC1=C[NH]C2=C1C=C(CC3COC(=O)N3)C=C2",2.457,2,2,5]
["S1654","Phenylbutazone","d5","L4000-02","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Phenylbutazone (Butazolidine) is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis.",308.37,"50-33-9",{"v":62,"d":"62.00"},201.06,"<1","N/A","http://selleckchem.com/products/Phenylbutazone(Butazolidin).html","C19H20N2O2","free base","Butazolidine","CCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3",3.954,2,0,5]
["S1662","Isradipine","e5","L4000-02","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Isradipine (PN 200-110) is a potent and selective L-type voltage-gated calcium channel blocker, used to treat high blood pressure.",371.39,"75695-93-1",{"v":74,"d":"74.00"},199.25,"<1","N/A","http://selleckchem.com/products/Isradipine(Dynacirc).html","C19H21N3O5","free base","PN 200-110","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC3=NON=C23)C(=O)OC(C)C)C",2.168,7,1,6]
["S1669","Loteprednol etabonate","f5","L4000-02","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Loteprednol etabonate is a potent glucocorticoid receptor agonist, used in treatment of inflammation of the eye due to allergies.",466.95,"82034-46-6",{"v":93,"d":"93.00"},199.16,"<1","N/A","http://selleckchem.com/products/Loteprednol-etabonate.html","C24H31ClO7","free base","N/A","CCOC(=O)OC1(CCC2C3CCC4=CC(=O)C=CC4(C)C3C(O)CC12C)C(=O)OCCl",3.865,6,1,7]
["S1673","Aminophylline","g5","L4000-02","in 10mM DMSO","PDE","Metabolism","Aminophylline (Phyllocontin) is a competitive nonselective phosphodiesterase inhibitor with an IC50 of 0.12 mM and also a nonselective adenosine receptor antagonist.",420.43,"317-34-0",{"v":53,"d":"53.00"},126.06,{"v":84,"d":"84.00"},{"v":199.8,"d":"199.80"},"http://selleckchem.com/products/Aminophylline(Truphylline).html","C16H24N10O4","Ethylenediamine","Phyllocontin","CN1C(=O)N(C)C2=C([NH]C=N2)C1=O.CN3C(=O)N(C)C4=C([NH]C=N4)C3=O.NCCN",-2.089,6,4,1]
["S1679","Flurbiprofen","h5","L4000-02","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs).",244.26,"5104-49-4",{"v":49,"d":"49.00"},200.61,"<1","N/A","http://selleckchem.com/products/Flurbiprofen(Ansaid).html","C15H13FO2","free base","N/A","CC(C(O)=O)C1=CC(=C(C=C1)C2=CC=CC=C2)F",{"v":3.68,"d":"3.680"},1,0,3]
["S1683","Ipratropium Bromide","a6","L4000-02","in 10mM DMSO","AChR","Neuronal Signaling","Ipratropium Bromide is an antagonist of M3 type muscarinic acetylcholine receptors, used for the treatment of chronic obstructive pulmonary disease (COPD).",412.37,"22254-24-6",{"v":83,"d":"83.00"},201.28,{"v":83,"d":"83.00"},201.28,"http://selleckchem.com/products/Ipratropium-bromide.html","C20H30BrNO3","Bromide","N/A","[Br-].CC(C)[N+]1(C)C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",-1.326,2,1,6]
["S1688","Betamethasone Dipropionate","b6","L4000-02","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Betamethasone Dipropionate (SCH 11460) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.",504.59,"5593-20-4",{"v":100,"d":"100.00"},198.18,"<1","N/A","http://selleckchem.com/products/Betamethasone-Dipropionate(Diprolene).html","C28H37FO7","Free Base","SCH 11460","CCC(=O)OCC(=O)C1(OC(=O)CC)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C",{"v":3.8,"d":"3.800"},6,1,8]
["S1689","Meprednisone","c6","L4000-02","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Meprednisone (NSC 527579, SCH 4358) is a glucocorticoid and a methylated derivative of prednisone.",372.46,"1247-42-3",{"v":75,"d":"75.00"},201.37,"<1","N/A","http://selleckchem.com/products/Betapar(Meprednisone).html","C22H28O5","free base","NSC 527579, SCH 4358","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3C(=O)CC2(C)C1(O)C(=O)CO",1.536,3,1,2]
["S1690","Betamethasone Valerate","d6","L4000-02","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Betamethasone Valerate is a moderately potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.",476.58,"2152-44-5",{"v":95,"d":"95.00"},199.34,"<1","N/A","http://selleckchem.com/products/Betamethasone-valerate(Betnovate).html","C27H37FO6","free base","N/A","CCCCC(=O)OC1(C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)CO",3.666,4,2,7]
["S1693","Carbamazepine","e6","L4000-02","in 10mM DMSO","Autophagy,Sodium Channel","Transmembrane Transporters","Carbamazepine (Carbatrol, NSC 169864) is a sodium channel blocker with IC50 of 131 μM in rat brain synaptosomes.",236.27,"298-46-4",{"v":47,"d":"47.00"},198.92,"<1","N/A","http://selleckchem.com/products/Carbamazepine(Carbatrol).html","C15H12N2O","free base","NSC 169864","NC(=O)N1C2=C(C=CC=C2)C=CC3=C1C=CC=C3",2.679,1,1,0]
["S1696","Hydrocortisone (NSC 10483)","f6","L4000-02","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Hydrocortisone (NSC 10483, Cortisol) is a steroid hormone or glucocorticoid produced by the adrenal gland.",362.46,"50-23-7",{"v":73,"d":"73.00"},{"v":201.4,"d":"201.40"},"<1","N/A","http://selleckchem.com/products/Hydrocortisone.html","C21H30O5","free base","Cortisol","CC12CCC(=O)C=C1CCC3C4CCC(O)(C(=O)CO)C4(C)CC(O)C23",1.283,2,2,2]
["S1701","Desonide","g6","L4000-02","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Desonide is a low potency topical corticosteroid.",416.51,"638-94-8",{"v":83,"d":"83.00"},199.27,"<1","N/A","http://selleckchem.com/products/Desonide.html","C24H32O6","free base","N/A","CC1(C)OC2CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC3(C)C2(O1)C(=O)CO",1.028,4,2,2]
["S1702","Didanosine","h6","L4000-02","in 10mM DMSO","Reverse Transcriptase","Microbiology","Didanosine is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.",236.23,"69655-05-6",{"v":47,"d":"47.00"},198.96,"<1","N/A","http://selleckchem.com/products/Didanosine(Videx).html","C10H12N4O3","free base","N/A","OCC1CCC(O1)[N]2C=NC3=C2N=CNC3=O",-0.844,4,2,2]
["S1703","Divalproex Sodium","a7","L4000-02","in 10mM DMSO","HDAC","Epigenetics","Divalproex Sodium, consisting of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form, is a HDAC inhibitor, used in the treatment for epilepsy.",310.41,"76584-70-8",{"v":62,"d":"62.00"},199.74,{"v":62,"d":"62.00"},199.74,"http://selleckchem.com/products/Divalproex-sodium.html","C8H16O2.C8H15O2.Na","Sodium Salt","N/A","[Na+].CCCC(CCC)C(O)=O.CCCC(CCC)C([O-])=O",4.025,1,0,10]
["S1709","Estradiol","b7","L4000-02","in 10mM DMSO","Estrogen/progestogen Receptor,Interleukins","Endocrinology & Hormones","Estradiol (17β-estradiol, β-Estradiol, E2, 17β-Oestradiol) is a human sex hormone and steroid, and the primary female sex hormone. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.",272.38,"50-28-2",{"v":54,"d":"54.00"},198.25,"<1","N/A","http://selleckchem.com/products/Estradiol.html","C18H24O2","free base","17β-estradiol, β-Estradiol, E2, 17β-Oestradiol","CC12CCC3C(CCC4=C3C=CC(=C4)O)C1CCC2O",3.838,0,2,0]
["S1713","Piroxicam","c7","L4000-02","in 10mM DMSO","COX","Neuronal Signaling","Piroxicam (CP 16171) is a non-selective COX inhibitor, used in the treatment of rheumatoid and osteoarthritis.",331.35,"36322-90-4",{"v":66,"d":"66.00"},199.19,"<1","N/A","http://selleckchem.com/products/Piroxicam(Feldene).html","C15H13N3O4S","free base","CP 16171","CN1C(=C(O)C2=C(C=CC=C2)[S]1(=O)=O)C(=O)NC3=NC=CC=C3",0.501,4,2,2]
["S1723","Indomethacin (NSC-77541)","d7","L4000-02","in 10mM DMSO","COX","Neuronal Signaling","Indomethacin (NSC-77541, Indometacin) is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively, used to reduce fever, pain, stiffness, and swelling.",357.79,"53-86-1",{"v":72,"d":"72.00"},201.24,"<1","N/A","http://selleckchem.com/products/Indomethacin(Indocid).html","C19H16ClNO4","free base","Indometacin,NSC-77541","COC1=CC=C2[N](C(=C(CC(O)=O)C2=C1)C)C(=O)C3=CC=C(Cl)C=C3",4.235,3,0,4]
["S1733","Methylprednisolone (NSC-19987)","e7","L4000-02","in 10mM DMSO","ACE,Apoptosis related,Autophagy,Glucocorticoid Receptor,Immunology & Inflammation related,Interleukins","Endocrinology & Hormones","Methylprednisolone (NSC-19987,U 7532) is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.",374.47,"83-43-2",{"v":75,"d":"75.00"},200.28,"<1","N/A","http://selleckchem.com/products/Methylprednisolone.html","C22H30O5","free base","NSC-19987,U 7532","CC1CC2C3CCC(O)(C(=O)CO)C3(C)CC(O)C2C4(C)C=CC(=O)C=C14",1.512,2,2,2]
["S1734","Meloxicam","f7","L4000-02","in 10mM DMSO","COX","Neuronal Signaling","Meloxicam is a selective COX inhibitor, used to relieve pain and fever effects.",{"v":351.4,"d":"351.40"},"71125-38-7",{"v":30,"d":"30.00"},85.37,"<1","N/A","http://selleckchem.com/products/Meloxicam(Mobic).html","C14H13N3O4S2","free base","N/A","CN1C(=C(O)C2=C(C=CC=C2)[S]1(=O)=O)C(=O)NC3=NC=C(C)S3",0.255,4,2,2]
["S1736","Methocarbamol","g7","L4000-02","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Methocarbamol (AHR 85) is a carbonic anhydrase inhibitor, used as a central muscle relaxant to treat skeletal muscle spasms.",241.24,"532-03-6",{"v":48,"d":"48.00"},198.97,{"v":2,"d":"2.00"},8.29,"http://selleckchem.com/products/Methocarbamol(Robaxin).html","C11H15NO5","free base","AHR 85","COC1=C(OCC(O)COC(N)=O)C=CC=C1",0.916,4,2,7]
["S1737","Prednisolone (NSC-9900)","h7","L4000-02","in 10mM DMSO","Glucocorticoid Receptor,Immunology & Inflammation related","Endocrinology & Hormones","Prednisolone (NSC-9900) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.",360.44,"50-24-8",{"v":72,"d":"72.00"},199.76,"<1","N/A","http://selleckchem.com/products/Prednisolone(Hydroretrocortine).html","C21H28O5","Free Base","NSC-9900","CC12CC(O)C3C(CCC4=CC(=O)C=CC34C)C1CCC2(O)C(=O)CO",{"v":1.26,"d":"1.260"},2,2,2]
["S1738","Telmisartan","a8","L4000-02","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Telmisartan (BIBR 277) is an angiotensin II receptor antagonist (ARB) used in the management of hypertension.",514.62,"144701-48-4",{"v":13,"d":"13.00"},25.26,"<1","N/A","http://selleckchem.com/products/Telmisartan(Micardis).html","C33H30N4O2","free base","BIBR 277","CCCC1=NC2=C(C=C(C=C2C)C3=NC4=C(C=CC=C4)[N]3C)[N]1CC5=CC=C(C=C5)C6=CC=CC=C6C(O)=O",7.799,3,0,7]
["S1747","Nimodipine","b8","L4000-02","in 10mM DMSO","Autophagy,Calcium Channel","Transmembrane Transporters","Nimodipine (BAY E 9736) is a dihydropyridine calcium channel blocker and an autophagy inhibitor, used in the treatment of high blood pressure.",418.44,"66085-59-4",{"v":84,"d":"84.00"},200.75,"<1","N/A","http://selleckchem.com/products/Nimodipine(Nimotop).html","C21H26N2O7","free base","BAY E 9736","COCCOC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OC(C)C)C",2.361,5,1,10]
["S1748","Nisoldipine","c8","L4000-02","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Nisoldipine (Sular, BAY K 5552) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM.",388.41,"63675-72-9",{"v":77,"d":"77.00"},198.24,"<1","N/A","http://selleckchem.com/products/Nisoldipine(Sular).html","C20H24N2O6","free base","BAY K 5552","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC=C2[N+]([O-])=O)C(=O)OCC(C)C)C",2.958,4,1,8]
["S1754","Oxybutynin","d8","L4000-02","in 10mM DMSO","AChR","Neuronal Signaling","Oxybutynin is a competitive antagonist of the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor, used to relieve urinary and bladder difficulties.",357.49,"5633-20-5",{"v":71,"d":"71.00"},198.61,"<1","N/A","http://selleckchem.com/products/Oxybutynin(Ditropan).html","C22H31NO3","Free Base","N/A","CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)C2=CC=CC=C2",4.646,2,0,10]
["S1759","Pitavastatin (NK-104) calcium","e8","L4000-02","in 10mM DMSO","Apoptosis related,Autophagy,COVID-19,HMG-CoA Reductase,Mitophagy","Metabolism","Pitavastatin Calcium (NK-104, P-872441, itavastatin, nisvastatin), a novel member of the medication class of statins, is a calcium salt formulation of pitavastatin which is a highly effective HMG-CoA reductase inhibitor. Pitavastatin Calcium attenuates AGEs-induced mitophagy via inhibition of ROS generation. Pitavastatin Calcium induces autophagy and apoptosis.",880.98,"147526-32-7",{"v":51,"d":"51.00"},57.89,"<1","N/A","http://selleckchem.com/products/Pitavastatin-calcium(Livalo).html","C50H46CaF2N2O8","Calcium salt","NK-104, P-872441, itavastatin, nisvastatin","[Ca++].OC(CC(O)C=CC1=C(C2=CC=C(F)C=C2)C3=CC=CC=C3N=C1C4CC4)CC([O-])=O.OC(CC(O)C=CC5=C(C6=CC=C(F)C=C6)C7=CC=CC=C7N=C5C8CC8)CC([O-])=O",{"v":4.96,"d":"4.960"},2,4,16]
["S1761","Suprofen","f8","L4000-02","in 10mM DMSO","COX","Neuronal Signaling","Suprofen(TN-762) is a dual COX-1/COX-2 inhibitor, used as a non-steroidal anti-inflammatory analgesic and antipyretic.",260.31,"40828-46-4",{"v":52,"d":"52.00"},199.76,"<1","N/A","http://selleckchem.com/products/Suprofen(Profenal).html","C14H12O3S","free base","TN-762","CC(C(O)=O)C1=CC=C(C=C1)C(=O)C2=CC=CS2",3.314,2,0,4]
["S1763","Quetiapine (ICI-204636) fumarate","g8","L4000-02","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Quetiapine Fumarate (ICI-204636) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression and shows affinity for various neurotransmitter receptors including serotonin, dopamine, histamine, and adrenergic receptors.",883.09,"111974-72-2",{"v":36,"d":"36.00"},40.77,"<1","N/A","http://selleckchem.com/products/Quetiapine-fumarate(Seroquel).html","C46H54N6O8S2","Fumarate","ICI-204636 fumarate","OCCOCCN1CCN(CC1)C2=NC3=CC=CC=C3SC4=C2C=CC=C4.OCCOCCN5CCN(CC5)C6=NC7=CC=CC=C7SC8=C6C=CC=C8.OC(=O)\\C=C\\C(O)=O",-0.718,6,2,14]
["S1771","Chlorprothixene","h8","L4000-02","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Chlorprothixene(Minithixen,Truxal) has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively.",315.86,"113-59-7",{"v":6,"d":"6.00"},{"v":19,"d":"19.00"},"<1","N/A","http://selleckchem.com/products/Chlorprothixene.html","C18H18ClNS","free base","Minithixen,Truxal","CN(C)CC/C=C1/C2=CC=CC=C2SC3=C1C=C(Cl)C=C3",5.123,0,0,3]
["S1789","Tetrabenazine (Xenazine)","a9","L4000-02","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Tetrabenazine(Xenazine,Ro 1-9569) acts primarily as a reversible high-affinity inhibitor of mono-amine uptake into granular vesicles of presynaptic neurons by binding selectively to VMAT-2; Also blocks dopamine D2 receptors, but this affinity is 1,000-fold lower than its affinity for VMAT-2.",317.42,"58-46-8",{"v":58,"d":"58.00"},182.72,"<1","N/A","http://selleckchem.com/products/Tetrabenazine(Nitoman).html","C19H27NO3","free base","Xenazine,Ro 1-9569","COC1=CC2=C(C=C1OC)C3CC(=O)C(CC(C)C)CN3CC2",3.365,3,0,4]
["S1792","Simvastatin (MK 733)","b9","L4000-02","in 10mM DMSO","Apoptosis related,Autophagy,Ferroptosis,HMG-CoA Reductase,Mitophagy","Metabolism","Simvastatin (MK-0733, MK 733) is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM in cell-free assays. Simvastatin induces ferroptosis, mitophagy, autophagy and apoptosis.",418.57,"79902-63-9",{"v":83,"d":"83.00"},198.29,"<1","N/A","http://selleckchem.com/products/Simvastatin(Zocor).html","C25H38O5","free base","MK-0733, MK 733","CCC(C)(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C12",4.634,4,1,7]
["S1799","Ranolazine","c9","L4000-02","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Ranolazine (CVT 303, RS 43285-003) is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina.",427.54,"95635-55-5",{"v":86,"d":"86.00"},201.15,"<1","N/A","http://selleckchem.com/products/Ranolazine(Ranexa).html","C24H33N3O4","Free Base","CVT 303, RS 43285-003","COC1=CC=CC=C1OCC(O)CN2CCN(CC2)CC(=O)NC3=C(C)C=CC=C3C",2.991,3,2,9]
["S1801","Ranitidine Hydrochloride","d9","L4000-02","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Ranitidine (AH19065) is a histamine H2-receptor antagonist, used to treat stomach or intestinal ulcers.",350.86,"66357-59-3",{"v":70,"d":"70.00"},199.51,{"v":70,"d":"70.00"},199.51,"http://selleckchem.com/products/Ranitidine-hydrochloride(Zantac).html","C13H22N4O3S.HCl","Hydrochloride","AH19065","Cl.CNC(/NCCSCC1=CC=C(CN(C)C)O1)=C\\[N+]([O-])=O",1.421,1,2,10]
["S1805","Acetylcholine Chloride","e9","L4000-02","in 10mM DMSO","AChR","Neuronal Signaling","The chemical compound Acetylcholine Chloride(ACh chloride) is a neurotransmitter in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans.",181.66,"60-31-1",{"v":36,"d":"36.00"},198.17,{"v":36,"d":"36.00"},198.17,"http://www.selleck.cn/products/Acetylcholine-chloride.html","C7H16NO2.Cl","Chloride","ACh chloride","[Cl-].CC(=O)OCC[N+](C)(C)C",-3.869,2,0,4]
["S1808","Nifedipine (BAY-a-1040)","f9","L4000-02","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Nifedipine (BAY-a-1040) is a dihydropyridine calcium channel blocker, used to lower hypertension and to treat angina.",346.33,"21829-25-4",{"v":69,"d":"69.00"},199.23,"<1","N/A","http://selleckchem.com/products/Nifedipine(Adalat).html","C17H18N2O6","free base","BAY-a-1040","COC(=O)C1=C(C)NC(=C(C1C2=C(C=CC=C2)[N+]([O-])=O)C(=O)OC)C",1.766,4,1,6]
["S1811","Amiloride (MK-870) HCl","g9","L4000-02","in 10mM DMSO","Calcium Channel,Serine Protease,Sodium Channel","Transmembrane Transporters","Amiloride (MK-870 HCl) is a selective T-type calcium channel blocker, an epithelial sodium channel blocker and a selective inhibitor of urokinase plasminogen activator (uPA)(Ki=7 μM).",266.09,"2016-88-8",{"v":53,"d":"53.00"},199.18,{"v":6,"d":"6.00"},22.55,"http://selleckchem.com/products/Amiloride-hydrochloride(Midamor).html","C6H8ClN7O.HCl","Hydrochloride","MK-870 HCl","Cl.NC(=N)NC(=O)C1=NC(=C(N)N=C1N)Cl",-0.366,3,4,2]
["S1813","Amlodipine Besylate","h9","L4000-02","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Amlodipine Besylate is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.",567.05,"111470-99-6",{"v":113,"d":"113.00"},199.28,"<1","N/A","http://selleckchem.com/products/Amlodipine-besylate(Norvasc).html","C20H25ClN2O5.C6H6O3S","Besylate","N/A","CCOC(=O)C1=C(COCCN)NC(=C(C1C2=C(Cl)C=CC=C2)C(=O)OC)C.O[S](=O)(=O)C3=CC=CC=C3",2.739,5,2,11]
["S1816","Chlorpheniramine Maleate","a10","L4000-02","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Chlorpheniramine Maleate (Chlorpheniramine maleate, Chlorphenamine, NCI-C55265) is an histamine H1 receptor antagonist with IC50 of 12 nM.",390.86,"113-92-8",{"v":78,"d":"78.00"},199.56,{"v":78,"d":"78.00"},199.56,"http://selleckchem.com/products/Chlorpheniramine-maleate.html","C16H19ClN2.C4H4O4","Maleate","NCI-C55265","CN(C)CCC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.OC(=O)\\C=C/C(O)=O",{"v":0.7,"d":"0.700"},3,0,7]
["S1827","Betaxolol HCl","b10","L4000-02","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Betaxolol (SL 75212) is a β1 adrenergic receptor blocker with IC50 of 6 μM.",343.89,"63659-19-8",{"v":69,"d":"69.00"},200.65,{"v":69,"d":"69.00"},200.65,"http://selleckchem.com/products/betaxolol-hydrochloride-betoptic.html","C18H29NO3.HCl","Hydrochloride","SL 75212 HCl","Cl.CC(C)NCC(O)COC1=CC=C(CCOCC2CC2)C=C1",2.959,2,2,11]
["S1828","Proparacaine HCl","c10","L4000-02","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Proparacaine HCl(Proxymetacaine Hydrochloride) is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM.",330.85,"5875-06-9",{"v":12,"d":"12.00"},36.27,{"v":66,"d":"66.00"},199.49,"http://selleckchem.com/products/proparacaine-hcl.html","C16H26N2O3.HCl","Hydrochloride","Proxymetacaine Hydrochloride","Cl.CCCOC1=C(N)C=C(C=C1)C(=O)OCCN(CC)CC",3.013,3,1,10]
["S1831","Carvedilol","d10","L4000-02","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Carvedilol (BM-14190, SKF 105517) is a non-selective beta blocker/alpha-1 blocker, used to treat congestive heart failure (CHF) and high blood pressure.",406.47,"72956-09-3",{"v":81,"d":"81.00"},199.28,"<1","N/A","http://selleckchem.com/products/carvedilol.html","C24H26N2O4","free base","BM-14190, SKF 105517","COC1=CC=CC=C1OCCNCC(O)COC2=C3C(=CC=C2)[NH]C4=C3C=CC=C4",4.014,3,3,10]
["S1832","Atracurium Besylate","e10","L4000-02","in 10mM DMSO","AChR","Neuronal Signaling","Atracurium Besylate (BW 33A, 51W89) is a neuromuscular blocking agent with ED95 of 0.2 mg/kg.",1243.48,"64228-81-5",{"v":100,"d":"100.00"},80.42,{"v":33,"d":"33.00"},26.54,"http://selleckchem.com/products/atracurium-besylate.html","C53H72N2O12.2(C6H5O3S)","Dibesylate","BW 33A, 51W89","COC1=CC=C(CC2C3=CC(=C(OC)C=C3CC[N+]2(C)CCC(=O)OCCCCCOC(=O)CC[N+]4(C)CCC5=CC(=C(OC)C=C5C4CC6=CC=C(OC)C(=C6)OC)OC)OC)C=C1OC.[O-][S](=O)(=O)C7=CC=CC=C7.[O-][S](=O)(=O)C8=CC=CC=C8",3.646,12,0,28]
["S1845","Cimetidine","f10","L4000-02","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Cimetidine (SKF-92334), a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.",252.34,"51481-61-9",{"v":51,"d":"51.00"},202.11,"<1","N/A","http://selleckchem.com/products/Cimetidine(Tagamet).html","C10H16N6S","free base","SKF-92334","CNC(NCCSCC1=C(C)[NH]C=N1)=NC#N",0.007,2,3,7]
["S1847","Clemastine (HS-592) fumarate","g10","L4000-02","in 10mM DMSO","Autophagy,Histamine Receptor,mTOR","Neuronal Signaling","Clemastine Fumarate (HS-592, Meclastine) is a selective histamine H1 receptor antagonist with IC50 of 3 nM. Clemastine stimulates autophagy via mTOR pathway.",459.96,"14976-57-9",{"v":35,"d":"35.00"},76.09,"<1","N/A","http://selleckchem.com/products/Clemastine-Fumarate.html","C21H26ClNO.C4H4O4","Fumarate","HS-592 fumarate, Meclastine fumarate","CN1CCCC1CCOC(C)(C2=CC=CC=C2)C3=CC=C(Cl)C=C3.OC(=O)\\C=C\\C(O)=O",{"v":1.81,"d":"1.810"},3,0,8]
["S1848","Curcumin","h10","L4000-02","in 10mM DMSO","Apoptosis related,Autophagy,Epigenetic Reader Domain,Ferroptosis,HCV,HDAC,Histone Acetyltransferase,HIV,Influenza Virus,NF-κB,Nrf2","Epigenetics","Curcumin (Diferuloylmethane, Natural Yellow 3, Turmeric yellow) is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase（IC50~25 μM）and Histone deacetylase (HDAC); activates Nrf2 pathway and supresses the activation of NF-κB. Curcumin induces mitophagy, autophagy, apoptosis, and cell cycle arrest with antitumor activity. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus, hepatitis C virus, HIV and so on.",368.38,"458-37-7",{"v":73,"d":"73.00"},198.16,"<1","N/A","http://selleckchem.com/products/Curcumin.html","C21H20O6","free base","Diferuloylmethane, Natural Yellow 3, Turmeric yellow","COC1=CC(=CC=C1O)/C=C/C(O)=C/C(=O)/C=C/C2=CC(=C(O)C=C2)OC",3.573,3,3,7]
["S1856","Metoprolol Tartrate","a11","L4000-02","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Metoprolol Tartrate (CGP 2175E) is a selective β1 receptor blocker medication, used to treat hypertension and heart failure.",684.81,"56392-17-7",{"v":100,"d":"100.00"},146.03,{"v":100,"d":"100.00"},146.03,"http://selleckchem.com/products/metoprolol-tartrate.html","2C15H25NO3.C4H6O6","Tartrate","CGP 2175E","COCCC1=CC=C(OCC(O)CNC(C)C)C=C1.COCCC2=CC=C(OCC(O)CNC(C)C)C=C2.OC(C(O)C(O)=O)C(O)=O",-3.559,6,6,21]
["S1865","Diltiazem HCl","b11","L4000-02","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Diltiazem (Tiazac, RG 83606) HCl is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions.",450.98,"33286-22-5",{"v":90,"d":"90.00"},199.57,{"v":90,"d":"90.00"},199.57,"http://selleckchem.com/products/Diltiazem-HCl(Tiazac).html","C22H26N2O4S.HCl","Hydrochloride","RG 83606 HCl","Cl.COC1=CC=C(C=C1)C2SC3=C(C=CC=C3)N(CCN(C)C)C(=O)C2OC(C)=O",3.475,4,0,7]
["S1866","Diphenhydramine HCl","c11","L4000-02","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Diphenhydramine HCl is a first-generation histamine H1 receptor antagonist, used in various allergic conditions such as rhinitis, urticaria and conjunctivitis.",291.82,"147-24-0",{"v":58,"d":"58.00"},198.75,{"v":58,"d":"58.00"},198.75,"http://selleckchem.com/products/Diphenhydramine-hydrochloride(Benadryl).html","C17H21NO.HCl","Hydrochloride","N/A","Cl.CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2",3.766,1,0,6]
["S1869","Dapoxetine HCl","d11","L4000-02","in 10mM DMSO","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Dapoxetine HCl (LY-210448) is a short-acting novel selective serotonin reuptake inhibitor, used for the treatment of premature ejaculation.",341.87,"129938-20-1",{"v":68,"d":"68.00"},198.91,{"v":68,"d":"68.00"},198.91,"http://selleckchem.com/products/Dapoxetine-hydrochloride(Priligy).html","C21H23NO.HCl","Hydrochloride","LY-210448","Cl.CN(C)C(CCOC1=C2C=CC=CC2=CC=C1)C3=CC=CC=C3",4.917,1,0,6]
["S1880","Roxatidine Acetate HCl","e11","L4000-02","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Roxatidine Acetate HCl(HOE 760) is a specific and competitive histamin H2-receptor antagonist, with IC50 of 3.2 μM, inhibits gastric acid secretion and ulcer formation.",{"v":384.9,"d":"384.90"},"93793-83-0",{"v":77,"d":"77.00"},200.05,{"v":77,"d":"77.00"},200.05,"http://selleckchem.com/products/roxatidine-acetate-hcl.html","C19H28N2O4.HCl","Hydrochloride","HOE 760","Cl.CC(=O)OCC(=O)NCCCOC1=CC=CC(=C1)CN2CCCCC2",2.148,4,1,10]
["S1885","Felodipine","f11","L4000-02","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Felodipine (CGH-869) is a selective L-type Ca2+ channel blocker with IC50 of 0.15 nM.",384.25,"72509-76-3",{"v":77,"d":"77.00"},200.39,"<1","N/A","http://selleckchem.com/products/Felodipine(Plendil).html","C18H19Cl2NO4","free base","CGH-869","CCOC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2Cl)Cl)C(=O)OC)C",3.549,4,1,6]
["S1888","Deflazacort","g11","L4000-02","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Deflazacort (MDL 458) is a glucocorticoid used as an anti-inflammatory and immunosuppressant.",441.52,"14484-47-0",{"v":88,"d":"88.00"},199.31,"<1","N/A","http://selleckchem.com/products/Deflazacor.html","C25H31NO6","free base","MDL 458","CC(=O)OCC(=O)C12N=C(C)OC1CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC23C",{"v":1.67,"d":"1.670"},6,1,4]
["S1890","Nizatidine","h11","L4000-02","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Nizatidine is a histamine H2 receptor antagonist with IC50 of 0.9 nM, also inhibits AChE with IC50 of 6.7 μM.",331.46,"76963-41-2",{"v":66,"d":"66.00"},199.12,{"v":28,"d":"28.00"},84.47,"http://selleckchem.com/products/Nizatidine(Axid).html","C12H21N5O2S2","free base","N/A","CNC(/NCCSCC1=CSC(=N1)CN(C)C)=C/[N+]([O-])=O",0.643,1,2,10]
["S1891","Carbidopa","a2","L4000-03","in 10mM DMSO","Decarboxylase","Metabolism","Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM.",226.23,"28860-95-9",{"v":4,"d":"4.00"},17.68,"<1","N/A","http://selleckchem.com/products/Carbidopa.html","C10H14N2O4","free base","N/A","CC(CC1=CC(=C(O)C=C1)O)(NN)C(O)=O",0.364,1,4,4]
["S1894","Valsartan (CGP-48933)","b2","L4000-03","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Valsartan (CGP-48933) is a selective angiotensin II receptor antagonist, used to treat high blood pressure and congestive heart failure.",435.52,"137862-53-4",{"v":87,"d":"87.00"},199.76,"<1","N/A","http://selleckchem.com/products/Valsartan(Diovan).html","C24H29N5O3","free base","CGP-48933","CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=N[NH]N=N3)C(C(C)C)C(O)=O",4.538,5,1,10]
["S1898","Tropisetron HCl","c2","L4000-03","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Tropisetron HCl (ICS 205-930) is a potent and selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist, used to treat nausea and vomiting following chemotherapy.",320.81,"105826-92-4",{"v":35,"d":"35.00"},{"v":109.1,"d":"109.10"},{"v":46,"d":"46.00"},143.39,"http://selleckchem.com/products/Tropisetron-hydrochloride.html","C17H20N2O2.HCl","Hydrochloride","ICS 205-930","Cl.CN1C2CCC1CC(C2)OC(=O)C3C=NC4=CC=CC=C34",2.366,3,0,3]
["S1899","Nicotinamide (NSC 13128)","d2","L4000-03","in 10mM DMSO","Sirtuin","DNA Damage/DNA Repair","Nicotinamide (Niacinamide, Vitamin PP, Nicotinic acid amide, Vitamin B3, NSC 27452,NSC 13128), a water-soluble vitamin, is an active component of coenzymes NAD and NADP, and also act as an inhibitor of sirtuins.",122.12,"98-92-0",{"v":24,"d":"24.00"},196.53,{"v":24,"d":"24.00"},196.53,"http://selleckchem.com/products/Nicotinamide(Niacinamide).html","C6H6N2O","free base","Niacinamide, Vitamin PP, Nicotinic acid amide, Vitamin B3, NSC 27452,NSC 13128","NC(=O)C1=CC=CN=C1",-0.319,2,1,1]
["S1903","Diclofenac Sodium","e2","L4000-03","in 10mM DMSO","COX","Neuronal Signaling","Diclofenac Sodium (GP 45840) is a non-selective COX inhibitor with IC50 of 0.5 μg/ml and 0.5 μg/ml for COX-1 and -2 in intact cells, respectively, used as a nonsteroidal anti-inflammatory drug (NSAID) to relieve pain and reduce swelling in flammation.",318.13,"15307-79-6",{"v":64,"d":"64.00"},201.18,{"v":14,"d":"14.00"},44.01,"http://selleckchem.com/products/Diclofenac-sodium.html","C14H10Cl2NNaO2","Sodium Salt","GP 45840","[Na+].[O-]C(=O)CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1",2.899,0,1,4]
["S1905","Amlodipine","f2","L4000-03","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Amlodipine (UK-48340) is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.",408.88,"88150-42-9",{"v":82,"d":"82.00"},200.55,"<1","N/A","http://selleckchem.com/products/Amlodipine(Norvasc).html","C20H25ClN2O5","free base","UK-48340","CCOC(=O)C1=C(COCCN)NC(=C(C1C2=C(Cl)C=CC=C2)C(=O)OC)C",1.576,5,2,10]
["S1913","Tropicamide","g2","L4000-03","in 10mM DMSO","AChR","Neuronal Signaling","Tropicamide(Ro 1-7683) is an anticholinergic and a muscarinic receptor subtype M4-preferring antagonist with IC50 of 8.0 nM.",284.35,"1508-75-4",{"v":57,"d":"57.00"},200.46,"<1","N/A","http://selleckchem.com/products/tropicamide.html","C17H20N2O2","free base","Ro 1-7683","CCN(CC1=CC=NC=C1)C(=O)C(CO)C2=CC=CC=C2",1.432,2,1,6]
["S1914","Pregnenolone","h2","L4000-03","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Pregnenolone(3β-Hydroxy-5-pregnen-20-one) is an endogenous steroid hormone, used in the treatment of fatigue, Alzheimer’s disease, trauma and injuries.",316.48,"145-13-1",{"v":22,"d":"22.00"},69.51,"<1","N/A","http://selleckchem.com/products/pregnenolone.html","C21H32O2","free base","3β-Hydroxy-5-pregnen-20-one","CC(=O)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C",3.624,1,1,1]
["S1920","Haloperidol","a3","L4000-03","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Haloperidol (Haldol) is an antipsychotic and butyrophenone.",375.86,"52-86-8",{"v":75,"d":"75.00"},199.54,"<1","N/A","http://selleckchem.com/products/Haloperidol(Haldol).html","C21H23ClFNO2","free base","N/A","OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C3=CC=C(Cl)C=C3",3.887,1,0,6]
["S1928","Alibendol","b3","L4000-03","in 10mM DMSO","Others","Others","Alibendol (EB 1856) is an antispasmodic,choleretic, and cholekinetic.",251.28,"26750-81-2",{"v":50,"d":"50.00"},198.98,"<1","N/A","http://selleckchem.com/products/alibendol.html","C13H17NO4","free base","EB 1856","COC1=CC(=CC(=C1O)C(=O)NCCO)CC=C",1.248,2,3,6]
["S1933","Triamcinolone","c3","L4000-03","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Triamcinolone is a glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated.",394.43,"124-94-7",{"v":78,"d":"78.00"},197.75,"<1","N/A","http://selleckchem.com/products/Triamcinolone(Aristocort).html","C21H27FO6","free base","N/A","CC12CC(O)C3(F)C(CCC4=CC(=O)C=CC34C)C1CC(O)C2(O)C(=O)CO",0.422,2,3,2]
["S1952","Methoxsalen","d3","L4000-03","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Methoxsalen (Xanthotoxin, NCI-C55903) is a naturally occurring photoactive substance found in the seeds of the Ammi majus (Umbelliferae) plant, used in the diagnosis and treatment of psoriasis; A CYP2A5/6 inhibitor.",216.19,"298-81-7",{"v":43,"d":"43.00"},{"v":198.9,"d":"198.90"},"<1","N/A","http://selleckchem.com/products/Methoxsalen(Oxsoralen).html","C12H8O4","free base","Xanthotoxin, NCI-C55903","COC1=C2OC=CC2=CC3=C1OC(=O)C=C3",2.187,4,0,1]
["S1959","Tolfenamic Acid","e3","L4000-03","in 10mM DMSO","COX","Neuronal Signaling","Tolfenamic Acid(Clotam) is a COX-2 inhibitor with IC50 of 0.2 μM.",{"v":261.7,"d":"261.70"},"13710-19-5",{"v":52,"d":"52.00"},{"v":198.7,"d":"198.70"},"<1","N/A","http://selleckchem.com/products/tolfenamic-acid.html","C14H12ClNO2","free base","Clotam","CC1=C(Cl)C=CC=C1NC2=C(C=CC=C2)C(O)=O",{"v":4.16,"d":"4.160"},1,1,3]
["S1960","Pranoprofen","f3","L4000-03","in 10mM DMSO","COX,PGES","Neuronal Signaling","Pranoprofen (Pyranoprofen,Pranopulin) is a non-steroidal COX inhibitor, used as an anti-inflammatory drug in ophthalmology.",255.27,"52549-17-4",{"v":51,"d":"51.00"},199.79,"<1","N/A","http://selleckchem.com/products/pranoprofen.html","C15H13NO3","free base","Pyranoprofen,Pranopulin","CC(C(O)=O)C1=CC2=C(OC3=NC=CC=C3C2)C=C1",{"v":3.05,"d":"3.050"},3,0,2]
["S1965","Primidone","g3","L4000-03","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Primidone (NCI-C56360) is an anticonvulsant of the pyrimidinedione class.",218.25,"125-33-7",{"v":44,"d":"44.00"},{"v":201.6,"d":"201.60"},"<1","N/A","http://selleckchem.com/products/Primidone(Mysoline).html","C12H14N2O2","free base","NCI-C56360","CCC1(C(=O)NCNC1=O)C2=CC=CC=C2",0.931,2,2,2]
["S1969","Nefiracetam","h3","L4000-03","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Nefiracetam (DZL 221) is a GABAergic, cholinergic, and monoaminergic neuronal system enhancer for Ro 5-4864-induced convulsions. Phase 2.",{"v":246.3,"d":"246.30"},"77191-36-7",{"v":49,"d":"49.00"},198.94,{"v":5,"d":"5.00"},{"v":20.3,"d":"20.30"},"http://selleckchem.com/products/Nefiracetam(Translon).html","C14H18N2O2","free base","DZL 221","CC1=CC=CC(=C1NC(=O)CN2CCCC2=O)C",1.443,2,1,3]
["S1975","Aripiprazole","a4","L4000-03","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Aripiprazole (OPC-14597) is a novel atypical antipsychotic drug that is reported to be a high-affinity 5-HT receptor partial agonist.",448.39,"129722-12-9",{"v":90,"d":"90.00"},200.72,"<1","N/A","http://selleckchem.com/products/aripiprazole-abilify.html","C23H27Cl2N3O2","free base","OPC-14597","ClC1=CC=CC(=C1Cl)N2CCN(CCCCOC3=CC=C4CCC(=O)NC4=C3)CC2",4.998,2,1,7]
["S1978","Methscopolamine","b4","L4000-03","in 10mM DMSO","AChR","Neuronal Signaling","Methscopolamine is a muscarinic acetylcholine receptor blocker.",398.29,"155-41-9",{"v":79,"d":"79.00"},198.35,{"v":67,"d":"67.00"},168.22,"http://selleckchem.com/products/Methscopolamine-bromide(Pamine).html","C18H24BrNO4","quaternary-N bromide salt","N/A","[Br-].C[N+]1(C)C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",-2.949,3,1,5]
["S1987","Mometasone furoate","c4","L4000-03","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Mometasone Furoate (SCH-32088,mometasone 17-furoate) is a glucocorticoid receptor agonist, used topically to reduce inflammation of the skin or in the airways.",521.43,"83919-23-7",{"v":6,"d":"6.00"},11.51,"<1","N/A","http://selleckchem.com/products/mometasone-furoate.html","C27H30Cl2O6","Furoate","SCH-32088,mometasone 17-furoate","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(Cl)C(O)CC2(C)C1(OC(=O)C5=CC=CO5)C(=O)CCl",4.616,5,1,5]
["S1990","Capsaicin(Vanilloid)","d4","L4000-03","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Capsaicin (Qutenza, Vanilloid) is an active component of chili peppers, which are plants belonging to the genus Capsicum.Capsaici is a TRPV1 agonist with an EC50 of 0.29 μM in HEK293 cells.",305.41,"404-86-4",{"v":61,"d":"61.00"},199.73,"<1","N/A","http://selleckchem.com/products/capsaicin.html","C18H27NO3","free base","Qutenza, Vanilloid","COC1=C(O)C=CC(=C1)CNC(=O)CCCC\\C=C\\C(C)C",{"v":3.91,"d":"3.910"},2,2,9]
["S1992","Fluticasone propionate","e4","L4000-03","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Fluticasone Propionate (CCI-187881) is a synthetic glucocorticoid, used to treat non-allergic and allergic rhinitis.",500.57,"80474-14-2",{"v":100,"d":"100.00"},199.77,"<1","N/A","http://selleckchem.com/products/fluticasone-propionate-Flonase-Veramyst.html","C25H31F3O5S","free base","CCI-187881","CCC(=O)OC1(C(C)CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)SCF",4.086,4,1,6]
["S1994","Lacidipine","f4","L4000-03","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Lacidipine (GX-1048, GR-43659X, SN-305) is a L-type calcium channel blocker, used for treating high blood pressure.",455.54,"103890-78-4",{"v":91,"d":"91.00"},199.76,"<1","N/A","http://selleckchem.com/products/lacidipine-lacipil-motens.html","C26H33NO6","free base","GX-1048, GR-43659X, SN-305","CCOC(=O)C1=C(C)NC(=C(C1C2=C(C=CC=C2)\\C=C\\C(=O)OC(C)(C)C)C(=O)OCC)C",3.824,6,1,11]
["S2007","Sulindac","g4","L4000-03","in 10mM DMSO","COX","Neuronal Signaling","Sulindac(MK-231) is a non-steroidal COX inhibitor, which potently inhibits prostaglandin synthesis, used in the treatment of acute or chronic inflammatory conditions.",356.41,"38194-50-2",{"v":71,"d":"71.00"},199.21,"<1","N/A","http://selleckchem.com/products/Sulindac(Clinoril).html","C20H17FO3S","free base","MK-231","CC1=C(CC(O)=O)C2=C(C=CC(=C2)F)\\C1=C/C3=CC=C(C=C3)[S](C)=O",3.639,2,0,4]
["S2011","Pramipexole 2HCl Monohydrate","h4","L4000-03","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Pramipexole 2HCl Monohydrate is a novel non-ergoline dopamine (DA) agonist, used to treat Parkinson's disease.",302.26,"191217-81-9",{"v":41,"d":"41.00"},135.64,{"v":60,"d":"60.00"},{"v":198.5,"d":"198.50"},"http://selleckchem.com/products/Pramipexole-dihydrochloride-monohydrate.html","C10H17N3S.2HCl.H2O","Dihydrochloride monohydrate","N/A","O.Cl.Cl.CCCNC1CCC2=C(C1)SC(=N2)N",{"v":1.94,"d":"1.940"},1,2,3]
["S2016","Mirtazapine","a5","L4000-03","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Mirtazapine (Org3770,6-Azamianserin) is an adrenergic and seroton receptor antagonist, used to treat depression.",265.35,"85650-52-8",{"v":53,"d":"53.00"},199.74,"<1","N/A","http://selleckchem.com/products/mirtazapine-remeron-avanza.html","C17H19N3","free base","Org3770,6-Azamianserin","CN1CCN2C(C1)C3=C(CC4=C2N=CC=C4)C=CC=C3",3.094,1,0,0]
["S2017","Benidipine HCl","b5","L4000-03","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Benidipine HCl (KW-3049,(±)- Benidipine) is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker.",542.02,"91599-74-5",{"v":8,"d":"8.00"},14.76,"<1","N/A","http://selleckchem.com/products/benidipine-hydrochloride.html","C28H31N3O6.HCl","Hydrochloride","KW-3049,(±)- Benidipine","Cl.COC(=O)C1=C(C)NC(=C(C1C2=CC(=CC=C2)[N+]([O-])=O)C(=O)OC3CCCN(C3)CC4=CC=CC=C4)C",{"v":4.36,"d":"4.360"},4,1,9]
["S2020","Formoterol Hemifumarate","c5","L4000-03","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Formoterol Hemifumarate (Eformoterol, CGP 25827A, NSC 299587, YM 08316,Formoterol fumarate) is a potent, selective and long-acting β2-adrenoceptor agonist used in the management of asthma and chronic obstructive pulmonary disease(COPD).",{"v":402.4,"d":"402.40"},"43229-80-7",{"v":80,"d":"80.00"},198.81,"<1","N/A","http://selleckchem.com/products/formoterol-hemifumarate.html","C19H24N2O4.1/2C4H4O4","Hemifumarate","Eformoterol, CGP 25827A, NSC 299587, YM 08316,Formoterol fumarate","COC1=CC=C(CC(C)NCC(O)C2=CC=C(O)C(=C2)NC=O)C=C1.COC3=CC=C(CC(C)NCC(O)C4=CC=C(O)C(=C4)NC=O)C=C3.OC(=O)\\C=C\\C(O)=O",-1.526,6,8,18]
["S2021","Chlormezanone","d5","L4000-03","in 10mM DMSO","Others","Others","Chlormezanone，a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.",273.74,"80-77-3",{"v":55,"d":"55.00"},200.92,"<1","N/A","http://selleckchem.com/products/Chlormezanone(Trancopal).html","C11H12ClNO3S","free base","N/A","CN1C(C2=CC=C(Cl)C=C2)[S](=O)(=O)CCC1=O",1.559,3,0,1]
["S2024","Ketotifen Fumarate","e5","L4000-03","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Ketotifen Fumarate(HC 20511 fumarate) is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer.",{"v":425.5,"d":"425.50"},"34580-14-8",{"v":8,"d":"8.00"},{"v":18.8,"d":"18.80"},"<1","N/A","http://selleckchem.com/products/ketotifen-fumarate-zaditor.html","C19H19NOS.C4H4O4","Fumarate","HC 20511 fumarate","CN1CCC(CC1)=C2C3=C(CC(=O)C4=C2C=CS4)C=CC=C3.OC(=O)\\C=C\\C(O)=O",0.772,3,0,2]
["S2025","Urapidil HCl","f5","L4000-03","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Urapidil HCl is a hydrochloride salt form of urapidil which is α1-adrenoceptor antagonist and 5-HT1A receptor agonist with pIC50 of 6.13 and 6.4 respectively.",423.94,"64887-14-5",{"v":24,"d":"24.00"},56.61,{"v":85,"d":"85.00"},{"v":200.5,"d":"200.50"},"http://selleckchem.com/products/urapidil-hydrochloride.html","C20H29N5O3.HCl","Hydrochloride","N/A","Cl.COC1=CC=CC=C1N2CCN(CCCNC3=CC(=O)N(C)C(=O)N3C)CC2",1.808,3,1,7]
["S2026","Ginkgolide A","g5","L4000-03","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Ginkgolide A (BN52020) is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist with a Ki of 14.5 μM.",{"v":408.4,"d":"408.40"},"15291-75-5",{"v":81,"d":"81.00"},198.33,"<1","N/A","http://selleckchem.com/products/ginkgolide-a.html","C20H24O9","free base","BN52020","CC1C(=O)OC2CC34C5CC(C(C)(C)C)C36C(O)C(=O)OC6OC4(C(=O)O5)C12O",-0.022,7,1,1]
["S2029","Uridine","h5","L4000-03","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Uridine (NSC 20256,β-Uridine, Uridin) is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond.",{"v":244.2,"d":"244.20"},"58-96-8",{"v":49,"d":"49.00"},200.66,{"v":49,"d":"49.00"},200.66,"http://selleckchem.com/products/uridine.html","C9H12N2O6","free base","NSC 20256,β-Uridine, Uridin","OCC1OC(C(O)C1O)N2C=CC(=O)NC2=O",-2.451,3,4,2]
["S2030","Flunarizine 2HCl","a6","L4000-03","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Flunarizine 2HCl (KW-3149, R14950) is a dihydrochloride salt form which is a calcium channel blocker with a Ki of 68 nM.",477.42,"30484-77-6",{"v":5,"d":"5.00"},10.47,"<1","N/A","http://selleckchem.com/products/flunarizine-dihydrochloride.html","C26H26F2N2.2HCl","2HCl","KW-3149, R14950","Cl.Cl.FC1=CC=C(C=C1)C(N2CCN(CC2)C\\C=C\\C3=CC=CC=C3)C4=CC=C(F)C=C4",6.699,0,0,6]
["S2032","Rebamipide","b6","L4000-03","in 10mM DMSO","CCK receptor","GPCR & G Protein","Rebamipide (OPC-12759,Proamipide) is a cholecystokinin type 1 (CCK1) receptor inhibitor for inhibiting [125I]BH-CCK-8S with IC50 of 37.7 μM.",370.79,"90098-04-7",{"v":74,"d":"74.00"},199.57,"<1","N/A","http://selleckchem.com/products/rebamipide.html","C19H15ClN2O4","free base","OPC-12759,Proamipide","OC(=O)C(CC1=CC(=O)NC2=C1C=CC=C2)NC(=O)C3=CC=C(Cl)C=C3",2.606,3,2,5]
["S2037","Candesartan Cilexetil","c6","L4000-03","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist with IC50 of 0.26 nM, used in the treatment of hypertension.",610.66,"145040-37-5",{"v":122,"d":"122.00"},199.78,"<1","N/A","http://selleckchem.com/products/Candesartan-cilexetil-Atacand.html","C33H34N6O6","free base","TCV-116","CCOC1=NC2=C([N]1CC3=CC=C(C=C3)C4=C(C=CC=C4)C5=NN=N[NH]5)C(=CC=C2)C(=O)OC(C)OC(=O)OC6CCCCC6",6.913,10,1,13]
["S2038","Phentolamine Mesylate","d6","L4000-03","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Phentolamine Mesylate(Phentolamine methanesulfonate) is a reversible and nonselective alpha-adrenergic receptor antagonist, used for the prevention or control of hypertensive episodes.",377.46,"65-28-1",{"v":76,"d":"76.00"},201.35,{"v":76,"d":"76.00"},201.35,"http://selleckchem.com/products/phentolamine-mesilate.html","C17H19N3O.CH4O3S","Mesylate","Phentolamine methanesulfonate","CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.C[S](O)(=O)=O",2.555,1,2,4]
["S2040","Nimesulide","e6","L4000-03","in 10mM DMSO","COX","Neuronal Signaling","Nimesulide is a relatively COX-2 selective inhibitor with IC50 of 26 μM.",308.31,"51803-78-2",{"v":62,"d":"62.00"},{"v":201.1,"d":"201.10"},"<1","N/A","http://selleckchem.com/products/Nimesulide.html","C13H12N2O5S","free base","N/A","C[S](=O)(=O)NC1=C(OC2=CC=CC=C2)C=C(C=C1)[N+]([O-])=O",2.195,3,1,5]
["S2041","Dyclonine HCl","f6","L4000-03","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Dyclonine HCl(Dyclocaine HCl) is a hydrochloride salt form of dyclonine which is an oral anaesthetic, reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation.",325.87,"536-43-6",{"v":15,"d":"15.00"},46.03,{"v":6,"d":"6.00"},18.41,"http://selleckchem.com/products/dyclonine-hydrochloride.html","C18H27NO2.HCl","Hydrochloride","Dyclocaine HCl","Cl.CCCCOC1=CC=C(C=C1)C(=O)CCN2CCCCC2",4.435,2,0,8]
["S2043","Memantine HCl","g6","L4000-03","in 10mM DMSO","NMDAR","Neuronal Signaling","Memantine HCl is an antagonist of NMDAR. It is also a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6 with IC50 of 1.12 μM and 242.4 μM, Ki of 0.51 μM and 84.4 μM, respectively.",215.76,"41100-52-1",{"v":43,"d":"43.00"},{"v":199.3,"d":"199.30"},{"v":30,"d":"30.00"},139.04,"http://selleckchem.com/products/memantine-hydrochloride-namenda.html","C12H21N.HCl","Hydrochloride","N/A","Cl.CC12C[CH]3CC(C)([CH2]1)C[C](N)(C3)C2",2.289,0,1,0]
["S2044","Cyproheptadine HCl","h6","L4000-03","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Cyproheptadine HCl(Periactin) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist.",323.86,"969-33-5",{"v":65,"d":"65.00"},{"v":200.7,"d":"200.70"},"<1","N/A","http://selleckchem.com/products/cyproheptadine-hydrochloride-periactin.html","C21H21N.HCl","Hydrochloride","Periactin","Cl.CN1CCC(CC1)=C2C3=C(C=CC=C3)C=CC4=C2C=CC=C4",4.744,0,0,0]
["S2046","Pioglitazone HCl","a7","L4000-03","in 10mM DMSO","Ferroptosis,P450 (e.g. CYP17),PPAR","Metabolism","Pioglitazone HCl (AD-4833, U-72107E) is an inhibitor of cytochrome P450 (CYP)2C8 and CYP3A4 enzymes. Pioglitazone HCl inhibits CYP2C8, CYP3A4 and CYP2C9 with Ki of 1.7 μM, 11.8 μM and 32.1 μM, respectively. Pioglitazone HCl is also a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist with EC50 of 0.93 μM and 0.99 μM for human PPARγ and mouse PPARγ, respectively. Pioglitazone HCl inhibits mitochondrial iron uptake, lipid peroxidation, and subsequent ferroptosis.",{"v":392.9,"d":"392.90"},"112529-15-4",{"v":79,"d":"79.00"},201.07,"<1","N/A","http://selleckchem.com/products/pioglitazone-hydrochloride-actos.html","C19H20N2O3S.HCl","Hydrochloride","AD-4833, U-72107E","Cl.CCC1=CC=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)N=C1",4.289,4,1,7]
["S2054","Orphenadrine Citrate","b7","L4000-03","in 10mM DMSO","AChR","Neuronal Signaling","Orphenadrine Citrate is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.",{"v":461.5,"d":"461.50"},"4682-36-4",{"v":92,"d":"92.00"},199.35,"<1","N/A","http://selleckchem.com/products/orphenadrine-citrate-norflex.html","C18H23NO.C6H8O7","Citrate","N/A","CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2C.OC(=O)CC(O)(CC(O)=O)C(O)=O",-0.483,4,0,11]
["S2059","Terazosin HCl Dihydrate","c7","L4000-03","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Terazosin HCl is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH).",459.92,"70024-40-7",{"v":26,"d":"26.00"},56.53,"<1","N/A","http://selleckchem.com/products/terazosin-hydrochloride-hytrin.html","C19H25N5O4.HCl.2H2O","HCl & Dihydrate","N/A","O.O.Cl.COC1=CC2=C(C=C1OC)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N",1.348,6,1,4]
["S2061","Lovastatin (MK-803)","d7","L4000-03","in 10mM DMSO","Autophagy,HMG-CoA Reductase","Metabolism","Lovastatin (MK-803, Mevinolin,Mevacor) is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM in a cell-free assay, used for lowering cholesterol (hypolipidemic agent). Lovastatin triggers autophagy.",404.54,"75330-75-5",{"v":8,"d":"8.00"},19.78,"<1","N/A","http://selleckchem.com/products/lovastatin-mevacor.html","C24H36O5","free base","Mevinolin,Mevacor","CCC(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C12",4.218,4,1,7]
["S2065","Lafutidine","e7","L4000-03","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Lafutidine (FRG-8813), a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.",431.55,"118288-08-7",{"v":86,"d":"86.00"},199.28,"<1","N/A","http://selleckchem.com/products/lafutidine.html","C22H29N3O4S","free base","FRG-8813","O=C(C[S](=O)CC1=CC=CO1)NC\\C=C/COC2=CC(=CC=N2)CN3CCCCC3",1.987,5,1,11]
["S2066","Moxonidine","f7","L4000-03","in 10mM DMSO","Imidazoline Receptor","GPCR & G Protein","Moxonidine (BDF5895) is a selective agonist at the imidazoline receptor subtype 1, used as antihypertensive agent.",241.68,"75438-57-2",{"v":24,"d":"24.00"},{"v":99.3,"d":"99.30"},"<1","N/A","http://selleckchem.com/products/moxonidine.html","C9H12ClN5O","free base","BDF5895","COC1=NC(=NC(=C1NC2=NCCN2)Cl)C",0.598,4,2,3]
["S2067","Ozagrel HCl","g7","L4000-03","in 10mM DMSO","P450 (e.g. CYP17),Prostaglandin Receptor","Metabolism","Ozagrel HCl (OKY-046) is a selective <n>thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.",264.71,"78712-43-3",{"v":52,"d":"52.00"},196.44,{"v":52,"d":"52.00"},196.44,"http://selleckchem.com/products/ozagrel-hydrochloride.html","C13H12N2O2.HCl","HCl","OKY-046 HCl","Cl.OC(=O)/C=C/C1=CC=C(C[N]2C=CN=C2)C=C1",1.986,2,0,4]
["S2072","Seratrodast(AA-2414)","h7","L4000-03","in 10mM DMSO","Prostaglandin Receptor","Metabolism","Seratrodast (AA-2414, ABT-001) is a potent and selective thromboxane A2 receptor (TP) antagonist which is used primarily in the treatment of asthma and used as anti-inflammatory agent.",354.44,"112665-43-7",{"v":71,"d":"71.00"},200.32,"<1","N/A","http://www.selleck.cn/products/seratrodast.html","C22H26O4","Free Base","ABT-001","CC1=C(C)C(=O)C(=C(C)C1=O)C(CCCCCC(O)=O)C2=CC=CC=C2",5.216,3,0,8]
["S2075","Rosiglitazone (BRL-49653) HCl","a8","L4000-03","in 10mM DMSO","PPAR","Metabolism","Rosiglitazone HCl (BRL-49653) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.",393.89,"302543-62-0",{"v":79,"d":"79.00"},200.56,"<1","N/A","http://selleckchem.com/products/rosiglitazone-hydrochloride.html","C18H19N3O3S.HCl","HCl","BRL-49653 HCl","Cl.CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C3=CC=CC=N3",{"v":3.65,"d":"3.650"},4,1,7]
["S2077","Atorvastatin Calcium","b8","L4000-03","in 10mM DMSO","Apoptosis related,Autophagy,HMG-CoA Reductase","Metabolism","Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. Atorvastatin Calcium induces apoptosis and autophagy.",1155.34,"134523-03-8",{"v":100,"d":"100.00"},86.55,"<1","N/A","http://selleckchem.com/products/atorvastatin-calcium-lipitor.html","2(C33H34FN2O5).Ca","Calcium","N/A","[Ca++].CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C([N]1CCC(O)CC(O)CC([O-])=O)C3=CC=C(F)C=C3)C4=CC=CC=C4.CC(C)C5=C(C(=O)NC6=CC=CC=C6)C(=C([N]5CCC(O)CC(O)CC([O-])=O)C7=CC=C(F)C=C7)C8=CC=CC=C8",8.163,2,6,24]
["S2078","Famotidine","c8","L4000-03","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Famotidine (MK208) is a histamine H2–receptor antagonist with IC50 of 0.6 mM, commonly used to treat heartburn, GERD, ulcers, and other digestive conditions.",337.45,"76824-35-6",{"v":67,"d":"67.00"},198.55,"<1","N/A","http://selleckchem.com/products/famotidine-pepcid.html","C8H15N7O2S3","free base","MK208","NC(=N)NC1=NC(=CS1)CSCCC(=N)N[S](N)(=O)=O",-1.328,3,4,9]
["S2080","Clevidipine Butyrate","d8","L4000-03","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Clevidipine Butyrate(Cleviprex) is a dihydropyridine calcium channel blocker,  uses as an agent for the reduction of blood pressure.",456.32,"167221-71-8",{"v":91,"d":"91.00"},199.42,"<1","N/A","http://selleckchem.com/products/cleviprex-clevidipine.html","C21H23Cl2NO6","free base","Cleviprex","CCCC(=O)OCOC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2Cl)Cl)C(=O)OC)C",4.145,6,1,10]
["S2082","Adiphenine HCl","e8","L4000-03","in 10mM DMSO","AChR","Neuronal Signaling","Adiphenine HCl(NSC 129224) is a nicotinic receptor inhibitor, used as an antispasmodic drug.",347.88,"50-42-0",{"v":30,"d":"30.00"},86.24,{"v":70,"d":"70.00"},201.22,"http://selleckchem.com/products/adiphenine-hcl.html","C20H25NO2.HCl","HCl","NSC 129224","Cl.CCN(CC)CCOC(=O)C(C1=CC=CC=C1)C2=CC=CC=C2",4.433,2,0,9]
["S2083","Procaterol HCl","f8","L4000-03","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Procaterol HCl (OPC-2009) is a short-acting β2-adrenergic receptor agonist with Kp of 8 nM, used for the treatment of asthma",326.82,"62929-91-3",{"v":65,"d":"65.00"},198.89,{"v":65,"d":"65.00"},198.89,"http://www.selleckchem.com/products/procaterol-hcl.html","C16H22N2O3.HCl","hydrochloride","OPC-2009","Cl.CCC(NC(C)C)C(O)C1=CC=C(O)C2=C1C=CC(=O)N2",2.781,1,4,5]
["S2084","Duloxetine HCl","g8","L4000-03","in 10mM DMSO","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Duloxetine HCl (LY-248686) is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).",333.88,"136434-34-9",{"v":67,"d":"67.00"},200.67,"<1","N/A","http://selleckchem.com/products/duloxetine-hcl-cymbalta.html","C18H19NOS.HCl","HCl","LY-248686 HCl","Cl.CNCCC(OC1=C2C=CC=CC2=CC=C1)C3=CC=CS3",4.228,1,1,6]
["S2085","Trimebutine","h8","L4000-03","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","Trimebutine (Mebutin) is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain.",387.47,"39133-31-8",{"v":50,"d":"50.00"},129.04,"<1","N/A","http://selleckchem.com/products/trimebutine.html","C22H29NO5","free base","Mebutin","CCC(COC(=O)C1=CC(=C(OC)C(=C1)OC)OC)(N(C)C)C2=CC=CC=C2",4.115,5,0,10]
["S2086","Ivabradine HCl","a9","L4000-03","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Ivabradine HCl (S 16257-2,S-18982 D6 hydrochloride), a new If inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent.",505.05,"148849-67-6",{"v":101,"d":"101.00"},199.98,{"v":82,"d":"82.00"},162.36,"http://selleckchem.com/products/ivabradine-hcl-procoralan.html","C27H36N2O5.HCl","HCl","S 16257-2,S-18982 D6 hydrochloride","Cl.COC1=CC2=C(CC(=O)N(CCCN(C)CC3CC4=CC(=C(OC)C=C34)OC)CC2)C=C1OC",3.753,5,0,10]
["S2087","Rivastigmine Tartrate","b9","L4000-03","in 10mM DMSO","AChR","Neuronal Signaling","Rivastigmine Tartrate (ENA 713) is a cholinesterase inhibitor with IC50 of 5.5 μM, and used as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease.",400.42,"129101-54-8",{"v":42,"d":"42.00"},104.89,{"v":80,"d":"80.00"},199.79,"http://selleckchem.com/products/rivastigmine-tartrate-exelon.html","C14H22N2O2.C4H6O6","Tartrate","ENA 713","CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C.OC(C(O)C(O)=O)C(O)=O",-2.099,4,2,8]
["S2090","Dexmedetomidine HCl","c9","L4000-03","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Dexmedetomidine HCl((+)-Medetomidine Hydrochloride) is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.",236.74,"145108-58-3",{"v":48,"d":"48.00"},202.75,"<1","N/A","http://selleckchem.com/products/dexmedetomidine-hcl-precedex.html","C13H16N2.HCl","HCl","(+)-Medetomidine Hydrochloride","Cl.CC(C1=CN=C[NH]1)C2=CC=CC(=C2C)C",3.378,1,1,2]
["S2091","Betaxolol","d9","L4000-03","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Betaxolol (SL 75212,Dextrobetaxolol) is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.",307.43,"63659-18-7",{"v":62,"d":"62.00"},201.67,{"v":62,"d":"62.00"},201.67,"http://selleckchem.com/products/betaxolol-betoptic.html","C18H29NO3","free base","SL 75212,Dextrobetaxolol","CC(C)NCC(O)COC1=CC=C(CCOCC2CC2)C=C1",2.577,2,2,11]
["S2092","Detomidine HCl","e9","L4000-03","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Detomidine HCl(MPV 253AII) produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.",222.71,"90038-01-0",{"v":45,"d":"45.00"},202.06,{"v":45,"d":"45.00"},202.06,"http://selleckchem.com/products/detomidine-hcl.html","C12H14N2.HCl","HCl","MPV 253AII","Cl.CC1=C(C)C(=CC=C1)CC2=C[NH]C=N2",3.053,1,1,2]
["S2096","Almotriptan Malate","f9","L4000-03","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Almotriptan Malate (LAS 31416) is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults.",469.55,"181183-52-8",{"v":94,"d":"94.00"},200.19,"<1","N/A","http://selleckchem.com/products/almotriptan-malate-axert.html","C17H25N3O2S.C4H6O5","Malate","LAS 31416","CN(C)CCC1=C[NH]C2=CC=C(C[S](=O)(=O)N3CCCC3)C=C12.OC(CC(O)=O)C(O)=O",-1.943,4,2,9]
["S2098","Bexarotene (LGD1069)","g9","L4000-03","in 10mM DMSO","Retinoid Receptor","Metabolism","Bexarotene (Targretin, LGD1069) is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.",{"v":348,"d":"348.00"},"153559-49-0",{"v":8,"d":"8.00"},22.99,"<1","N/A","http://selleckchem.com/products/bexarotene.html","C24H28O2","free base","Targretin","CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(O)=O)C(C)(C)CCC2(C)C",6.405,1,0,3]
["S2102","Rasagiline Mesylate","h9","L4000-03","in 10mM DMSO","MAO","Metabolism","Rasagiline Mesylate (TVP-1012,(R)-AGN1135 mesylate,TVP1012 mesylate) is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.",267.34,"161735-79-1",{"v":53,"d":"53.00"},198.25,{"v":53,"d":"53.00"},198.25,"http://selleckchem.com/products/rasagiline-mesylate.html","C12H13N.CH4O3S","Mesylate","TVP-1012,(R)-AGN1135 mesylate,TVP1012 mesylate","C[S](O)(=O)=O.C#CCNC1CCC2=CC=CC=C12",2.705,0,1,2]
["S2103","Naltrexone HCl","a10","L4000-03","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","Naltrexone HCl(PTI-901) is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence.",377.86,"16676-29-2",{"v":14,"d":"14.00"},37.05,{"v":14,"d":"14.00"},37.05,"http://selleckchem.com/products/naltrexone-hcl.html","C20H23NO4.HCl","Hydrochloride","PTI-901","Cl.OC1=CC=C2CC3N(CCC45C(OC1=C24)C(=O)CCC35O)CC6CC6",2.039,2,1,2]
["S2104","Levosulpiride","b10","L4000-03","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Levosulpiride(RV-12309,S-(-)-Sulpiride) is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent.",341.43,"23672-07-3",{"v":69,"d":"69.00"},202.09,"<1","N/A","http://selleckchem.com/products/levosulpiride-levogastrol.html","C15H23N3O4S","free base","RV-12309,S-(-)-Sulpiride","CCN1CCCC1CNC(=O)C2=C(OC)C=CC(=C2)[S](N)(=O)=O",0.704,4,2,6]
["S2108","Flunixin Meglumin","c10","L4000-03","in 10mM DMSO","COX","Neuronal Signaling","Flunixin Meglumin(Banamine) is a potent inhibitor of the enzyme cyclooxygenase (COX) used as analgesic agent with anti-inflammatory and antipyretic activity.",491.46,"42461-84-7",{"v":98,"d":"98.00"},199.41,{"v":98,"d":"98.00"},199.41,"http://selleckchem.com/products/flunixin-meglumin.html","C14H11F3N2O2.C7H17NO5","Meglumin","Banamine","CNCC(O)C(O)C(O)C(O)CO.CC1=C(C=CC=C1NC2=NC=CC=C2C(O)=O)C(F)(F)F",-1.676,2,7,10]
["S2113","Cisatracurium Besylate","d10","L4000-03","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Cisatracurium Besylate(51W89) is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.",1243.48,"96946-42-8",{"v":249,"d":"249.00"},200.24,{"v":47,"d":"47.00"},{"v":37.8,"d":"37.80"},"http://selleckchem.com/products/cisatracurium-besylate-nimbex.html","C53H72N2O12.2C6H5O3S","Besylate","51W89","COC1=CC=C(CC2C3=CC(=C(OC)C=C3CC[N+]2(C)CCC(=O)OCCCCCOC(=O)CC[N+]4(C)CCC5=CC(=C(OC)C=C5C4CC6=CC=C(OC)C(=C6)OC)OC)OC)C=C1OC.[O-][S](=O)(=O)C7=CC=CC=C7.[O-][S](=O)(=O)C8=CC=CC=C8",3.646,12,0,28]
["S2114","Dronedarone HCl","e10","L4000-03","in 10mM DMSO","Calcium Channel,Potassium Channel,Sodium Channel","Transmembrane Transporters","Dronedarone HCl (SR33589) is a multichannel blocker targeting potassium channel, sodium channel and calcium channel, used as an antiarrhythmic drug for treatment of atrial fibrillation (AF).",593.22,"141625-93-6",{"v":80,"d":"80.00"},134.86,"<1","N/A","http://selleckchem.com/products/dronedarone-hcl-multaq.html","C31H44N2O5S.HCl","HCl","SR33589","Cl.CCCCN(CCCC)CCCOC1=CC=C(C=C1)C(=O)C2=C(CCCC)OC3=CC=C(N[S](C)(=O)=O)C=C23",7.397,5,1,18]
["S2118","Ibutilide Fumarate","f10","L4000-03","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Ibutilide Fumarate (U-70226E,Corvert Fumarate) is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells.",885.23,"122647-32-9",{"v":89,"d":"89.00"},100.54,{"v":89,"d":"89.00"},100.54,"http://selleckchem.com/products/ibutilide-fumarate.html","(C20H36N2O3S)2.C4H4O4","Fumarate","U-70226E,Corvert Fumarate","CCCCCCCN(CC)CCCC(O)C1=CC=C(N[S](C)(=O)=O)C=C1.CCCCCCCN(CC)CCCC(O)C2=CC=C(N[S](C)(=O)=O)C=C2.OC(=O)\\C=C\\C(O)=O",1.954,6,4,30]
["S2126","Naftopidil","g10","L4000-03","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Naftopidil (KT-611) is a selective α1-adrenergic receptor antagonist with Ki of 3.7 nM, 20 nM, and 1.2 nM for α1a, α1b, and α1d, respectively, used for the treatment of benign prostatic hyperplasia.",392.49,"57149-07-2",{"v":79,"d":"79.00"},201.28,"<1","N/A","http://selleckchem.com/products/Naftopidil(Flivas).html","C24H28N2O3","Free Base","KT-611","COC1=CC=CC=C1N2CCN(CC2)CC(O)COC3=C4C=CC=CC4=CC=C3",3.962,2,1,7]
["S2127","S-(+)-Rolipram","h10","L4000-03","in 10mM DMSO","PDE","Metabolism","S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.",275.34,"85416-73-5",{"v":55,"d":"55.00"},199.75,"<1","N/A","http://selleckchem.com/products/sRolipram.html","C16H21NO3","free base","N/A","COC1=C(OC2CCCC2)C=C(C=C1)C3CNC(=O)C3",2.349,3,1,4]
["S2130","Atropine sulfate monohydrate","a11","L4000-03","in 10mM DMSO","AChR,ADC Cytotoxin","Neuronal Signaling","Atropine sulfate monohydrate is a competitive antagonist for the muscarinic acetylcholine receptor, used to decrease the production of saliva and secretions of the airway prior to surgery.",694.83,"5908-99-6",{"v":139,"d":"139.00"},200.05,{"v":139,"d":"139.00"},200.05,"http://selleckchem.com/products/Atropine-sulfate-monohydrate.html","2(C17H23NO3).H2O.H2SO4","Sulfate monohydrate","N/A","O.CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN4C5CCC4CC(C5)OC(=O)C(CO)C6=CC=CC=C6.O[S](O)(=O)=O",2.628,4,2,10]
["S2131","Roflumilast (B9302-107)","b11","L4000-03","in 10mM DMSO","PDE","Metabolism","Roflumilast (APTA 2217, B9302-107, BY 217, BYK 20869) is a selective inhibitor of PDE4 with IC50 of 0.2-4.3 nM in a cell-free assay.",403.21,"162401-32-3",{"v":81,"d":"81.00"},200.89,"<1","N/A","http://selleckchem.com/products/Roflumilast(Daxas).html","C17H14Cl2F2N2O3","free base","APTA 2217, B9302-107, BY 217, BYK 20869","FC(F)OC1=CC=C(C=C1OCC2CC2)C(=O)NC3=C(Cl)C=NC=C3Cl",4.402,4,1,7]
["S2149","GSK1292263","c11","L4000-03","in 10mM DMSO","GPR","Endocrinology & Hormones","GSK1292263 is a novel GPR119 agonist, showing potential for the treatment of type 2 diabetes. Phase 2.",456.56,"1032823-75-8",{"v":34,"d":"34.00"},74.47,"<1","N/A","http://selleckchem.com/products/GSK1292263.html","C23H28N4O4S","free base","N/A","CC(C)C1=NOC(=N1)N2CCC(CC2)COC3=CN=C(C=C3)C4=CC=C(C=C4)[S](C)(=O)=O",3.893,7,0,7]
["S2153","CGS 21680 HCl","d11","L4000-03","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","CGS 21680 HCl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor.",535.98,"124431-80-7",{"v":100,"d":"100.00"},186.57,"<1","N/A","http://selleckchem.com/products/CGS-21680-hydrochloride.html","C23H29N7O6.HCl","Hydrochloride","N/A","Cl.CCNC(=O)C1OC(C(O)C1O)[N]2C=NC3=C2N=C(NCCC4=CC=C(CCC(O)=O)C=C4)N=C3N",0.911,6,5,10]
["S2156","LY2886721","e11","L4000-03","in 10mM DMSO","BACE","Neuronal Signaling","LY2886721 is a BACE inhibitor used for the treatment of Alzheimer's Disease. Phase 1/2.",390.41,"1262036-50-9",{"v":9,"d":"9.00"},23.05,"<1","N/A","http://selleckchem.com/products/LY-2886721.html","C18H16F2N4O2S","free base","N/A","NC1=NC2(COCC2CS1)C3=CC(=CC=C3F)NC(=O)C4=NC=C(F)C=C4",2.134,4,2,3]
["S2160","Almorexant HCl","f11","L4000-03","in 10mM DMSO","OX Receptor","GPCR & G Protein","Almorexant HCl (ACT-078573) is an orally active, dual orexin receptor antagonist with IC50 of 6.6 nM and 3.4 nM for OX1 and OX2 receptor, respectively. Phase 3.",549.02,"913358-93-7",{"v":72,"d":"72.00"},131.14,"<1","N/A","http://selleckchem.com/products/almorexant-hcl.html","C29H32ClF3N2O3","Hydrochloride","ACT-078573 HCl","Cl.CNC(=O)C(N1CCC2=C(C=C(OC)C(=C2)OC)C1CCC3=CC=C(C=C3)C(F)(F)F)C4=CC=CC=C4",6.438,3,1,9]
["S2168","PD128907 HCl","g11","L4000-03","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","PD 128907 HCl is a potent and selective dopamine D3 receptor agonist, with EC50 of 0.64 nM, exhibits 53-fold selectivity over dopamine D2 receptor.",285.77,"112960-16-4",{"v":12,"d":"12.00"},41.99,{"v":50,"d":"50.00"},174.97,"http://selleckchem.com/products/PD-128907.html","C14H19NO3.HCl","Hydrochloride","N/A","Cl.CCCN1CCOC2C1COC3=CC=C(O)C=C23",2.463,2,1,2]
["S2215","DAPT (GSI-IX)","h11","L4000-03","in 10mM DMSO","Apoptosis related,Autophagy,Beta Amyloid,Secretase","Proteases","DAPT (GSI-IX, LY-374973) is a novel γ-secretase inhibitor, which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells. DAPT enhances the apoptosis of human tongue carcinoma cells and regulates autophagy.",432.46,"208255-80-5",{"v":86,"d":"86.00"},198.86,"<1","N/A","http://selleckchem.com/products/DAPT-GSI-IX.html","C23H26F2N2O4","free base","LY-374973","CC(NC(=O)CC1=CC(=CC(=C1)F)F)C(=O)NC(C(=O)OC(C)(C)C)C2=CC=CC=C2",3.385,4,2,9]
["S2228","Belnacasan (VX-765)","a2","L4000-04","in 10mM DMSO","Caspase","Apoptosis","Belnacasan (VX-765) is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM in a cell-free assay. Phase 2.",{"v":509,"d":"509.00"},"273404-37-8",{"v":100,"d":"100.00"},196.46,"<1","N/A","http://selleckchem.com/products/VX-765.html","C24H33ClN4O6","free base","N/A","CCOC1OC(=O)CC1NC(=O)C2CCCN2C(=O)C(NC(=O)C3=CC(=C(N)C=C3)Cl)C(C)(C)C",1.698,6,3,8]
["S2261","Andrographolide","b2","L4000-04","in 10mM DMSO","NF-κB","NF-κB","Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata.",350.45,"5508-58-7",{"v":70,"d":"70.00"},199.74,"<1","N/A","http://selleckchem.com/products/Andrographolide.html","C20H30O5","free base","N/A","CC1(CO)C(O)CCC2(C)C(C\\C=C\\3C(O)COC3=O)C(=C)CCC12",2.056,2,3,3]
["S2269","Baicalin (NSC-661431)","c2","L4000-04","in 10mM DMSO","GABA Receptor,PREP","Neuronal Signaling","Baicalin (NSC-661431) is a known prolyl endopeptidase inhibitor and affects the GABA receptors.",446.36,"21967-41-9",{"v":89,"d":"89.00"},199.39,"<1","N/A","http://selleckchem.com/products/Baicalin.html","C21H18O11","free base","N/A","OC1C(O)C(OC(C1O)C(O)=O)OC2=C(O)C(=C3C(=O)C=C(OC3=C2)C4=CC=CC=C4)O",0.608,5,5,4]
["S2276","Bilobalide","d2","L4000-04","in 10mM DMSO","Others","Others","Bilobalide is a biologically active terpenic trilactone present in Ginkgo biloba.",{"v":326.3,"d":"326.30"},"33570-04-6",{"v":65,"d":"65.00"},{"v":199.2,"d":"199.20"},"<1","N/A","http://selleckchem.com/products/Bilobalide.html","C15H18O8","free base","N/A","CC(C)(C)C1(O)CC2OC(=O)CC23C(=O)OC4OC(=O)C(O)C134",-0.641,6,1,1]
["S2277","Caffeic Acid","e2","L4000-04","in 10mM DMSO","Lipoxygenase,TRP Channel","Transmembrane Transporters","Caffeic acid is a hydroxycinnamic acid, a naturally occurring organic compound. Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO).",180.16,"331-39-5",{"v":36,"d":"36.00"},199.82,"<1","N/A","http://selleckchem.com/products/Caffeic-acid.html","C9H8O4","free base","N/A","OC(=O)/C=C/C1=CC=C(O)C(=C1)O",1.443,1,2,2]
["S2282","Cinchonidine","f2","L4000-04","in 10mM DMSO","Anti-infection,Serotonin Transporter","Microbiology","Cinchonidine is an alkaloid used in asymmetric synthesis in organic chemistry.",294.39,"485-71-2",{"v":59,"d":"59.00"},200.41,"<1","N/A","http://selleckchem.com/products/Cinchonidine.html","C19H22N2O","free base","N/A","OC(C1CC2CCN1CC2C=C)C3=CC=NC4=CC=CC=C34",{"v":2.75,"d":"2.750"},1,1,3]
["S2287","Cytisine","g2","L4000-04","in 10mM DMSO","AChR","Neuronal Signaling","Cytisine (Baphitoxine, Sophorine) is a nicotinic acetylcholine receptor agonist.",190.24,"485-35-8",{"v":38,"d":"38.00"},199.75,{"v":38,"d":"38.00"},199.75,"http://selleckchem.com/products/Cytisine(Baphitoxine,-Sophorine).html","C11H14N2O","free base","Baphitoxine,Sophorine","O=C1C=CC=C2C3CNCC(C3)CN12",-0.338,1,1,0]
["S2302","Glycyrrhizin (NSC 167409)","h2","L4000-04","in 10mM DMSO","Dehydrogenase,High-mobility Group,MAO","Metabolism","Glycyrrhizin (NSC 167409, Glycyrrhizic Acid) is a direct HMGB1(high mobility group box 1) inhibitor that inhibits HMGB1-dependent inflammatory molecule expression and oxidative stress; modulates P38 and P-JNK but not p-ERK signalling; Also inhibits 11 beta-hydroxysteroid dehydrogenase and monoamine oxidase (MAO).",822.93,"1405-86-3",{"v":100,"d":"100.00"},121.52,"<1","N/A","http://selleckchem.com/products/Glycyrrhizic-acid.html","C42H62O16","free base","N/A","CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O)OC6OC(C(O)C(O)C6OC7OC(C(O)C(O)C7O)C(O)=O)C(O)=O",2.417,8,5,7]
["S2304","Gramine","a3","L4000-04","in 10mM DMSO","ADC Cytotoxin,AdipoR,Adrenergic Receptor","Metabolism","Gramine (Donaxine) is a natural indole alkaloid isolated from giant reed, acts as an active adiponectin receptor (AdipoR) agonist, with IC50 of 3.2 µM and 4.2 µM for AdipoR2 and AdipoR1, respectively. Gramine is also a human and mouse β2-Adrenergic receptor (β2-AR) agonist.",174.24,"87-52-5",{"v":35,"d":"35.00"},200.87,"<1","N/A","http://selleckchem.com/products/Gramine.html","C11H14N2","free base","N/A","CN(C)CC1=C[NH]C2=C1C=CC=C2",2.197,0,1,2]
["S2308","Hesperetin","b3","L4000-04","in 10mM DMSO","Histamine Receptor,TGF-beta/Smad","TGF-beta/Smad","Hesperetin is a bioflavonoid and, to be more specific, a flavanone.",302.27,"520-33-2",{"v":60,"d":"60.00"},{"v":198.5,"d":"198.50"},"<1","N/A","http://selleckchem.com/products/Hesperetin.html","C16H14O6","free base","N/A","COC1=CC=C(C=C1O)C2CC(=O)C3=C(O)C=C(O)C=C3O2",2.357,3,3,2]
["S2312","Icariin","c3","L4000-04","in 10mM DMSO","PDE","Metabolism","Icariin is a cGMP-specific PDE5 inhibitor with IC50 of 0.432 μM, 167-fold more selective for PDE5 than PDE4.",676.66,"489-32-7",{"v":50,"d":"50.00"},73.89,"<1","N/A","http://selleckchem.com/products/Icariin.html","C33H40O15","free base","N/A","COC1=CC=C(C=C1)C2=C(OC3OC(C)C(O)C(O)C3O)C(=O)C4=C(O2)C(=C(OC5OC(CO)C(O)C(O)C5O)C=C4O)CC=C(C)C",0.983,7,8,9]
["S2314","Kaempferol (NSC 407289)","d3","L4000-04","in 10mM DMSO","Estrogen/progestogen Receptor,Fatty Acid Synthase","Endocrinology & Hormones","Kaempferol (NSC 407289, Robigenin), a natural flavonol, functions as an ERRα and ERRγ inverse agonist. It inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase.",286.23,"520-18-3",{"v":57,"d":"57.00"},199.14,"<1","N/A","http://selleckchem.com/products/Kaempferol.html","C15H10O6","free base","Robigenin","OC1=CC=C(C=C1)C2=C(O)C(=O)C3=C(O)C=C(O)C=C3O2",1.872,2,4,1]
["S2318","Lappaconitine","e3","L4000-04","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Lappaconitine (LC) is a natural diterpenoid alkaloid (DTA), acting as a human heart sodium channel blocker and possessing a wide range of biological activities, including anti-arrhythmic, anti-inflammatory, antioxidative, anticancer, epileptiform etc.",{"v":584.7,"d":"584.70"},"32854-75-4",{"v":16,"d":"16.00"},27.36,"N/A","N/A","http://selleckchem.com/products/lappaconitine.html","C32H44N2O8","free base","N/A","CCN1CC2(CCC(OC)C34C2CC(C13)C5(O)CC(OC)C6CC4C5(O)C6OC)OC(=O)C7=CC=CC=C7NC(C)=O",0.029,6,1,8]
["S2322","(+)-Matrine","f3","L4000-04","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","Matrine((+)-Matrine) is an alkaloid found in plants from the Sophora family, which has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist.",248.36,"519-02-8",{"v":49,"d":"49.00"},197.29,{"v":11,"d":"11.00"},44.29,"http://selleckchem.com/products/matrine.html","C15H24N2O","free base","N/A","O=C1CCCC2C3CCCN4CCCC(CN12)C34",1.417,1,0,0]
["S2331","Neohesperidin Dihydrochalcone (Nhdc)","g3","L4000-04","in 10mM DMSO","Others","Others","Neohesperidin dihydrochalcone(Nhdc, NCI-c60764), sometimes abbreviated to neohesperidin DC or simply NHDC, is an artificial sweetener derived from citrus.",612.58,"20702-77-6",{"v":100,"d":"100.00"},163.24,"<1","N/A","http://selleckchem.com/products/Neohesperidin-dihydrochalcone(Nhdc).html","C28H36O15","free base","NCI-c60764","COC1=C(O)C=C(CCC(=O)C2=C(O)C=C(OC3OC(CO)C(O)C(O)C3OC4OC(C)C(O)C(O)C4O)C=C2O)C=C1",-0.048,6,9,10]
["S2337","Osthole","h3","L4000-04","in 10mM DMSO","Others","Others","Osthol is an O-methylated coumarin, which is found in the plants such as Cnidium monnieri, Angelica archangelica and Angelica pubescens.",244.29,"484-12-8",{"v":49,"d":"49.00"},200.58,"<1","N/A","http://selleckchem.com/products/Osthole(Osthol).html","C15H16O3","free base","Osthol","COC1=CC=C2C=CC(=O)OC2=C1CC=C(C)C",{"v":3.74,"d":"3.740"},3,0,3]
["S2339","Paeonol","a4","L4000-04","in 10mM DMSO","MAO","Metabolism","Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 μM.",166.17,"552-41-0",{"v":33,"d":"33.00"},198.59,"<1","N/A","http://selleckchem.com/products/Paeonol(Peonol).html","C9H10O3","free base","Peonol","COC1=CC(=C(C=C1)C(C)=O)O",1.311,2,1,2]
["S2346","Puerarin","b4","L4000-04","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Puerarin (Kakonein), an isoflavones found in the root of Radix puerariae, is a 5-HT2C receptor and benzodiazepine site antagonist.",416.38,"3681-99-0",{"v":86,"d":"86.00"},206.54,"<1","N/A","http://selleckchem.com/products/Puerarin(Kakonein).html","C21H20O9","free base","Kakonein","OCC1OC(OC2=C(O)C=CC3=C2OC=C(C3=O)C4=CC=C(O)C=C4)C(O)C(O)C1O",{"v":0.21,"d":"0.210"},4,6,4]
["S2347","Quercetin Dihydrate","c4","L4000-04","in 10mM DMSO","PI3K,Sirtuin","PI3K/Akt/mTOR","Quercetin (Sophoretin), a polyphenolic flavonoid found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine, is utilized in many different cultures for their nervous system and anticancer effects. Quercetin (dihydrate), a natural flavonoid, is a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC50s of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively.",338.27,"6151-25-3",{"v":67,"d":"67.00"},198.07,"<1","N/A","http://selleckchem.com/products/Quercetin-dihydrate(Sophoretin).html","C15H10O7.2H2O","Dihydrate","Sophoretin","O.O.OC1=CC(=C2C(=O)C(=C(OC2=C1)C3=CC=C(O)C(=C3)O)O)O",1.216,2,5,1]
["S2349","Rutaecarpine","d4","L4000-04","in 10mM DMSO","COX","Neuronal Signaling","Rutaecarpine (Rutecarpine) is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs; a new class of COX-2 inhibitor.",287.32,"84-26-4",{"v":24,"d":"24.00"},83.53,"<1","N/A","http://selleckchem.com/products/Rutaecarpine(Rutecarpine).html","C18H13N3O","free base","Rutecarpine","O=C1N2CCC3=C([NH]C4=C3C=CC=C4)C2=NC5=C1C=CC=C5",3.359,2,1,0]
["S2351","Salicin","e4","L4000-04","in 10mM DMSO","COX","Neuronal Signaling","Salicin (Salicoside, Salicine) is a phenol β-glycosid produced from willow bark that shows anti-inflammatory effects. It is a natural, non-selective COX-1 and COX-2 inhibitor.",286.28,"138-52-3",{"v":57,"d":"57.00"},199.11,{"v":24,"d":"24.00"},83.83,"http://selleckchem.com/products/Salicin(Salicoside,-Salicine).html","C13H18O7","free base","Salicoside,Salicine","OCC1OC(OC2=CC=CC=C2CO)C(O)C(O)C1O",-0.947,2,5,4]
["S2359","Sinomenine","f4","L4000-04","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Sinomenine (Cucoline, Kukoline), a pure alkaloid extracted from the chinese medical plant Sinomenium acutum, is used for the treatment of rheumatism and arthritis.",329.39,"115-53-7",{"v":65,"d":"65.00"},197.33,{"v":65,"d":"65.00"},197.33,"http://selleckchem.com/products/Sinomenine(Cucoline).html","C19H23NO4","free base","Cucoline, Kukoline","COC1=CC2C3CC4=C(C(=C(OC)C=C4)O)C2(CCN3C)CC1=O",1.674,3,1,2]
["S2362","Synephrine","g4","L4000-04","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Synephrine (Oxedrine), a natural protoalkaloid in the extract of bitter orange and other citrus species, is commonly used for weight loss.",167.21,"94-07-5",{"v":33,"d":"33.00"},197.36,"<1","N/A","http://selleckchem.com/products/Synephrine(Oxedrine).html","C9H13NO2","free base","Oxedrine","CNCC(O)C1=CC=C(O)C=C1",0.615,0,3,3]
["S2363","Tangeretin","h4","L4000-04","in 10mM DMSO","Antioxidant","Apoptosis","Tangeretin (Tangeritin), a natural polymethoxylated flavone concentrated in the peel of citrus fruits, is known to have antiproliferative, antiinvasive, antimetastatic and antioxidant activities.",372.37,"481-53-8",{"v":8,"d":"8.00"},21.48,"<1","N/A","http://selleckchem.com/products/Tangeretin(Tangeritin).html","C20H20O7","free base","Tangeritin","COC1=CC=C(C=C1)C2=CC(=O)C3=C(OC)C(=C(OC)C(=C3O2)OC)OC",3.054,7,0,6]
["S2373","Yohimbine HCl","a5","L4000-04","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Yohimbine (Antagonil) has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.",{"v":390.9,"d":"390.90"},"65-19-0",{"v":12,"d":"12.00"},{"v":30.7,"d":"30.70"},"<1","N/A","http://selleckchem.com/products/Yohimbine-hydrochloride(Antagonil).html","C21H26N2O3.HCl","Hydrochloride","Antagonil","Cl.COC(=O)C1C(O)CCC2CN3CCC4=C([NH]C5=C4C=CC=C5)C3CC12",3.204,2,2,2]
["S2374","5-hydroxytryptophan (5-HTP)","b5","L4000-04","in 10mM DMSO","Others","Others","5-Hydroxytryptophan (5-HTP, NSC-92523), also known as oxitriptan (INN), is a naturally occurring amino acid and chemical precursor for the treatment of depression.",220.22,"56-69-9",{"v":44,"d":"44.00"},{"v":199.8,"d":"199.80"},{"v":4,"d":"4.00"},18.16,"http://selleckchem.com/products/5-hydroxytryptophan(5-HTP).html","C11H12N2O3","free base","NSC-92523","NC(CC1=C[NH]C2=CC=C(O)C=C12)C(O)=O",-1.554,1,3,3]
["S2377","Biochanin A","c5","L4000-04","in 10mM DMSO","FAAH","Metabolism","Biochanin A (4-Methylgenistein), an O-methylated isoflavone from Trifolium pratense, inhibits protein tyrosine kinase (PTK) of epidermal growth factor receptor with IC50 values of 91.5 μM.",284.26,"491-80-5",{"v":57,"d":"57.00"},200.52,"<1","N/A","http://selleckchem.com/products/Biochanin-A(4-Methylgenistein).html","C16H12O5","free base","4-Methylgenistein","COC1=CC=C(C=C1)C2=COC3=CC(=CC(=C3C2=O)O)O",2.366,3,2,2]
["S2378","Butylscopolamine Bromide","d5","L4000-04","in 10mM DMSO","AChR","Neuronal Signaling","Butylscopolamine Bromide (Scopolamine Butylbromide,(-)-Scopolamine butylbromide, Hyoscine butylbromide), is a peripherally acting antimuscarinic, anticholinergic agent used as an abdominal-specific antispasmodic.",440.37,"149-64-4",{"v":88,"d":"88.00"},199.83,{"v":88,"d":"88.00"},199.83,"http://selleckchem.com/products/butylscopolamine-bromide.html","C21H30NO4.Br","Bromide","Scopolamine Butylbromide,(-)-Scopolamine butylbromide, Hyoscine butylbromide","[Br-].CCCC[N+]1(C)C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",{"v":-1.62,"d":"-1.620"},3,1,8]
["S2383","Gastrodin","e5","L4000-04","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Gastrodin (Gastrodine), an anti-inflammatory polyphenol extracted from Chinese natural herbal Gastrodia elata Blume., benefits neurodegenerative diseases.",286.28,"62499-27-8",{"v":50,"d":"50.00"},174.65,"<1","N/A","http://selleckchem.com/products/Gastrodin(Gastrodine).html","C13H18O7","free base","Gastrodine","OCC1OC(OC2=CC=C(CO)C=C2)C(O)C(O)C1O",-0.947,2,5,4]
["S2396","Salidroside","f5","L4000-04","in 10mM DMSO","Mitophagy,mTOR,PREP","PI3K/Akt/mTOR","Salidroside (Rhodioloside), a phenylpropanoid glycoside isolated from Rhodiola rosea, has been reported to have a broad spectrum of pharmacological properties. Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.",{"v":300.3,"d":"300.30"},"10338-51-9",{"v":60,"d":"60.00"},{"v":199.8,"d":"199.80"},{"v":60,"d":"60.00"},{"v":199.8,"d":"199.80"},"http://selleckchem.com/products/Salidroside-Rhodioloside.html","C14H20O7","free base","Rhodioloside","OCC1OC(OCCC2=CC=C(O)C=C2)C(O)C(O)C1O",-0.443,2,5,5]
["S2397","Palmatine chloride","g5","L4000-04","in 10mM DMSO","Calcium Channel","Neuronal Signaling","Palmatine hydrochloride (Palmatine chloride (6CI,7CI); Fibrauretin) is a hydrochloride salt of palmatine which is a protoberberine alkaloid.",387.86,"10605-02-4",{"v":77,"d":"77.00"},198.53,{"v":5,"d":"5.00"},12.89,"http://selleckchem.com/products/Palmatine-chloride.html","C21H22NO4.Cl","Chloride","N/A","[Cl-].COC1=CC=C2C=C3C4=C(CC[N+]3=CC2=C1OC)C=C(OC)C(=C4)OC",1.488,4,0,4]
["S2399","Dihydromyricetin","h5","L4000-04","in 10mM DMSO","GABA Receptor,ROS","Neuronal Signaling","Dihydromyricetin (Ampelopsin, Ampeloptin) is a natural antioxidant flavonoid from Ampelopsis grossedentata.",320.25,"27200-12-0",{"v":64,"d":"64.00"},199.84,"<1","N/A","http://selleckchem.com/products/Dihydromyricetin-Ampeloptin.html","C15H12O8","free base","Ampeloptin","OC1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(O)C(=C3)O)O",1.237,2,6,1]
["S2403","Tetrandrine (NSC-77037)","a6","L4000-04","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Tetrandrine (NSC-77037, Fanchinine, d-Tetrandrine), a bis-benzylisoquinoline alkaloid derived from Stephania tetrandra, is a calcium channel blocker.",622.75,"518-34-3",{"v":7,"d":"7.00"},11.24,"<1","N/A","http://www.selleck.cn/products/Tetrandrine-Fanchinine.html","C38H42N2O6","Free Base","Fanchinine, d-Tetrandrine","COC1=CC=C2CC3N(C)CCC4=CC(=C(OC)C(=C34)OC5=C(OC)C=C6CCN(C)C(CC7=CC=C(OC1=C2)C=C7)C6=C5)OC",7.218,6,0,4]
["S2410","Paeoniflorin (NSC 178886)","b6","L4000-04","in 10mM DMSO","COX,HIF","Immunology & Inflammation","Paeoniflorin (NSC 178886,Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin reduces COX-2 expression. Paeoniflorin alleviates liver fibrosis by inhibiting HIF-1α through mTOR-dependent pathway.",480.46,"23180-57-6",{"v":96,"d":"96.00"},199.81,{"v":96,"d":"96.00"},199.81,"http://selleckchem.com/products/paeoniflorin.html","C23H28O11","free base","NSC 178886,Peoniflorin","CC12CC3(O)OC(O1)C4(COC(=O)C5=CC=CC=C5)C3CC24OC6OC(CO)C(O)C(O)C6O",-1.283,6,4,7]
["S2411","Geniposide","c6","L4000-04","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Geniposide is an iridoid glycoside isolated from the fruit of Gardenia jasminoides Ellis.",388.37,"24512-63-8",{"v":78,"d":"78.00"},200.84,{"v":78,"d":"78.00"},200.84,"http://selleckchem.com/products/geniposide.html","C17H24O10","free base","N/A","COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C3C1CC=C3CO",-2.066,5,5,6]
["S2415","Astragaloside A","d6","L4000-04","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Astragaloside A (Astragaloside IV) is the primary pure saponin isolated from Astragalus membranaceus, which has been widely used for the treatment of cardiovascular diseases.",784.97,"83207-58-3",{"v":100,"d":"100.00"},127.39,"<1","N/A","http://selleckchem.com/products/astragaloside-a.html","C41H68O14","free base","N/A","CC(C)(O)C1CCC(C)(O1)C2C(O)CC3(C)C4CC(OC5OC(CO)C(O)C(O)C5O)C6C(C)(C)C(CCC67CC47CCC23C)OC8OCC(O)C(O)C8O",-0.348,5,8,7]
["S2437","Rotundine","e6","L4000-04","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.",355.43,"483-14-7",{"v":8,"d":"8.00"},22.51,"<1","N/A","http://selleckchem.com/products/rotundine.html","C21H25NO4","free base","L-tetrahydropalmatine, L-THP","COC1=CC2=C(C=C1OC)C3CC4=CC=C(OC)C(=C4CN3CC2)OC",3.599,4,0,4]
["S2438","Synephrine HCl","f6","L4000-04","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","SynephrineHCl (Oxedrine, p-Synephrine) is a sympathomimetic α-adrenergic receptor (AR) agonist.",203.67,"5985-28-4",{"v":14,"d":"14.00"},68.74,{"v":41,"d":"41.00"},201.31,"http://selleckchem.com/products/synephrine-hcl.html","C9H13NO2.HCl","Hydrochloride","N/A","Cl.CNCC(O)C1=CC=C(O)C=C1",0.997,0,3,3]
["S2446","Levosimendan","g6","L4000-04","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Levosimendan(OR1259,OR1855,Simsndan) is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC), provides treatment for heart failure.",280.28,"141505-33-1",{"v":56,"d":"56.00"},{"v":199.8,"d":"199.80"},"<1","N/A","http://selleckchem.com/products/levosimendan.html","C14H12N6O","free base","OR1259,OR1855,Simsndan","CC1CC(=O)NN=C1C2=CC=C(NN=C(C#N)C#N)C=C2",1.486,3,2,3]
["S2451","Amantadine HCl","h6","L4000-04","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Amantadine HCl (1-adamantanamine) is used to treat or prevent infections of the respiratory tract caused by a certain virus.",{"v":187.7,"d":"187.70"},"665-66-7",{"v":38,"d":"38.00"},202.45,{"v":38,"d":"38.00"},202.45,"http://selleckchem.com/products/Amantadine-hydrochloride(Symmetrel).html","C10H17N.HCl","Hydrochloride","1-adamantanamine HCl","Cl.N[C]12CC3[CH2][CH](C[CH]([CH2]3)C1)C2",1.877,0,1,0]
["S2452","Amfebutamone (Bupropion) HCl","a7","L4000-04","in 10mM DMSO","AChR,Dopamine Receptor","Neuronal Signaling","Amfebutamone (Bupropion) HCl(Wellbutrin) is a selective norepinephrine-dopamine reuptake inhibitor with IC50 of 6.5 and 3.4 μM for the reuptake of dopamine and norepinephrine, respectively.",{"v":276.2,"d":"276.20"},"31677-93-7",{"v":8,"d":"8.00"},28.96,"<1","N/A","http://selleckchem.com/products/Amfebutamone-hydrochloride(Bupropion).html","C13H18ClNO.HCl","Hydrochloride","Wellbutrin","Cl.CC(NC(C)(C)C)C(=O)C1=CC=CC(=C1)Cl",3.501,1,1,4]
["S2454","Bupivacaine HCl","b7","L4000-04","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Bupivacaine HCl binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, used for treating cardiac arrhythmias.",324.89,"18010-40-7",{"v":65,"d":"65.00"},200.07,{"v":23,"d":"23.00"},70.79,"http://selleckchem.com/products/Bupivacaine-hydrochloride(Marcain).html","C18H28N2O.HCl","Hydrochloride","N/A","Cl.CCCCN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",4.692,1,1,5]
["S2455","Bethanechol chloride","c7","L4000-04","in 10mM DMSO","AChR","Neuronal Signaling","Bethanechol chloride(Myocholine,Urecholine) is a selective muscarinic receptor agonist without any effect on nicotinic receptors.",196.68,"590-63-6",{"v":39,"d":"39.00"},198.29,{"v":39,"d":"39.00"},198.29,"http://selleckchem.com/products/Carbamyl-beta-methylcholine-chloride(Bethanechol-chloride).html","C7H17N2O2.Cl","quaternary-N Chloride salt","Myocholine,Urecholine","[Cl-].CC(C[N+](C)(C)C)OC(N)=O",-3.702,2,1,4]
["S2456","Chlorpromazine HCl","d7","L4000-04","in 10mM DMSO","Dopamine Receptor,Potassium Channel","Neuronal Signaling","Chlorpromazine HCl (Sonazine) is a dopamine and potassium channel inhibitor with IC50 of 6.1 and 16 μM for inward-rectifying K+ currents and time-independent outward currents.",355.33,"69-09-0",{"v":71,"d":"71.00"},199.81,{"v":71,"d":"71.00"},199.81,"http://selleckchem.com/products/Chlorpromazine-hydrochloride(Sonazine).html","C17H19ClN2S.HCl","Hydrochloride","Sonazine","Cl.CN(C)CCCN1C2=C(SC3=C1C=C(Cl)C=C3)C=CC=C2",5.121,0,0,4]
["S2458","Clonidine HCl","e7","L4000-04","in 10mM DMSO","Adrenergic Receptor,Autophagy","Neuronal Signaling","Clonidine HCl(Kapvay) is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg.",{"v":266.5,"d":"266.50"},"4205-91-8",{"v":53,"d":"53.00"},198.87,{"v":53,"d":"53.00"},198.87,"http://selleckchem.com/products/Clonidine-hydrochloride(Catapres).html","C9H9Cl2N3.HCl","Hydrochloride","Kapvay","Cl.ClC1=C(NC2=NCCN2)C(=CC=C1)Cl",2.736,1,2,2]
["S2459","Clozapine","f7","L4000-04","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Clozapine (HF 1854, LX 100-129) is an atypical antipsychotic drug by acting as a 5-HT antagonist, used in the treatment of schizophrenia.",326.82,"5786-21-0",{"v":65,"d":"65.00"},198.89,"<1","N/A","http://selleckchem.com/products/Clozapine(Clozaril).html","C18H19ClN4","free base","HF 1854, LX 100-129","CN1CCN(CC1)C2=NC3=C(NC4=C2C=CC=C4)C=CC(=C3)Cl",3.422,1,1,1]
["S2460","Pramipexole","g7","L4000-04","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Pramipexole (SND 919,Mirapexin,Sifrol,Mirapex) is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.",211.33,"104632-26-0",{"v":42,"d":"42.00"},198.74,"<1","N/A","http://selleckchem.com/products/Pramipexole-Mirapex.html","C10H17N3S","Free Base","SND 919,Mirapexin,Sifrol,Mirapex","CCCNC1CCC2=C(C1)SC(=N2)N",1.383,1,2,3]
["S2461","Domperidone","h7","L4000-04","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Domperidone is an oral dopamine D2 receptor antagonist, used to treat nausea and vomiting.",425.91,"57808-66-9",{"v":48,"d":"48.00"},{"v":112.7,"d":"112.70"},"<1","N/A","http://selleckchem.com/products/Domperidone(Motilium).html","C22H24ClN5O2","free base","N/A","ClC1=CC2=C(C=C1)N(C3CCN(CCCN4C(=O)NC5=C4C=CC=C5)CC3)C(=O)N2",2.453,2,2,5]
["S2466","Estriol","a8","L4000-04","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estriol (NSC-12169) is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.",288.39,"50-27-1",{"v":57,"d":"57.00"},197.65,"<1","N/A","http://selleckchem.com/products/Estriol(Oestriol).html","C18H24O3","free base","NSC-12169","CC12CCC3C(CCC4=CC(=CC=C34)O)C1CC(O)C2O",2.871,0,3,0]
["S2470","Fluocinolone Acetonide","b8","L4000-04","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Fluocinolone Acetonide (Flucort-N) is a corticosteroid that binds to the cytosolic glucocorticoid receptor.",{"v":452.5,"d":"452.50"},"67-73-2",{"v":90,"d":"90.00"},{"v":198.9,"d":"198.90"},"<1","N/A","http://selleckchem.com/products/Fluocinolone-acetonide(Flucort-N).html","C24H30F2O6","free base","Flucort-N","CC1(C)OC2CC3C4CC(F)C5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(O1)C(=O)CO",0.995,4,2,2]
["S2471","Gallamine Triethiodide","c8","L4000-04","in 10mM DMSO","AChR","Neuronal Signaling","Gallamine Triethiodide  is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM.",891.53,"65-29-2",{"v":100,"d":"100.00"},112.17,{"v":100,"d":"100.00"},112.17,"http://selleckchem.com/products/Gallamine-triethiodide(Flaxedil).html","C30H60I3N3O3","tri-quaternary-N iodide salt","N/A","[I-].[I-].[I-].CC[N+](CC)(CC)CCOC1=C(OCC[N+](CC)(CC)CC)C(=CC=C1)OCC[N+](CC)(CC)CC",-8.065,3,0,21]
["S2480","Loperamide HCl","d8","L4000-04","in 10mM DMSO","Autophagy,Opioid Receptor","Neuronal Signaling","Loperamide HCl (ADL 2-1294,R-18553 hydrochloride) is a selective μ-opioid receptor agonist opioid with Ki of 3.3 nM, 15-fold and 350-fold selective over the δ subtype and the κ subtype of the opioid receptor, used against diarrhea resulting from gastroenteritis or inflammatory bowel disease.",{"v":513.5,"d":"513.50"},"34552-83-5",{"v":22,"d":"22.00"},42.84,"<1","N/A","http://selleckchem.com/products/Loperamide-hydrochloride.html","C29H33ClN2O2.HCl","Hydrochloride","ADL 2-1294,R-18553 hydrochloride","Cl.CN(C)C(=O)C(CCN1CCC(O)(CC1)C2=CC=C(Cl)C=C2)(C3=CC=CC=C3)C4=CC=CC=C4",5.017,1,0,7]
["S2481","Manidipine","e8","L4000-04","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Manidipine(CV-4093,(±)-Manidipine) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive.",{"v":610.7,"d":"610.70"},"89226-50-6",{"v":122,"d":"122.00"},199.77,"<1","N/A","http://selleckchem.com/products/Manidipine(Manyper).html","C35H38N4O6","free base","CV-4093,(±)-Manidipine","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OCCN3CCN(CC3)C(C4=CC=CC=C4)C5=CC=CC=C5)C",5.058,4,1,12]
["S2482","Manidipine 2HCl","f8","L4000-04","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Manidipine 2HCl (CV-4093) is a HCl salt form of Manidipine, which is a calcium channel blocker with IC50 of 2.6 nM, used clinically as an antihypertensive. Phase 4.",683.62,"89226-75-5",{"v":21,"d":"21.00"},30.72,"<1","N/A","http://selleckchem.com/products/Manidipine-dihydrochloride(CV-4093).html","C35H38N4O6.2HCl","Dihydrochloride","CV-4093","Cl.Cl.COC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OCCN3CCN(CC3)C(C4=CC=CC=C4)C5=CC=CC=C5)C",5.822,4,1,12]
["S2491","Nitrendipine","g8","L4000-04","in 10mM DMSO","Autophagy,Calcium Channel","Transmembrane Transporters","Nitrendipine (Bayotensin) is a dihydropyridine calcium channel blocker with an IC50 of 95 nM.",360.37,"39562-70-4",{"v":72,"d":"72.00"},199.79,"<1","N/A","http://selleckchem.com/products/Nitrendipine.html","C18H20N2O6","free base","Bayotensin","CCOC(=O)C1=C(C)NC(=C(C1C2=CC(=CC=C2)[N+]([O-])=O)C(=O)OC)C",2.115,4,1,7]
["S2493","Olanzapine","h8","L4000-04","in 10mM DMSO","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Olanzapine (LY170053,Zyprexa, Zalasta, Zolafren, Olzapin, Oferta, Zypadhera) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist.",312.44,"132539-06-1",{"v":62,"d":"62.00"},198.44,"<1","N/A","http://selleckchem.com/products/Olanzapine(Zyprexa).html","C17H20N4S","free base","LY170053,Zyprexa, Zalasta, Zolafren, Olzapin, Oferta, Zypadhera","CN1CCN(CC1)C2=NC3=C(NC4=C2C=C(C)S4)C=CC=C3",{"v":2.69,"d":"2.690"},1,1,1]
["S2494","Olopatadine HCl","a9","L4000-04","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Olopatadine HCl(ALO4943A,KW4679) is a histamine blocker and mast cell stabilizer with an IC50 of 559 μM for the release of histamine.",373.87,"140462-76-6",{"v":75,"d":"75.00"},{"v":200.6,"d":"200.60"},{"v":13,"d":"13.00"},34.77,"http://selleckchem.com/products/Olopatadine-hydrochloride(Opatanol).html","C21H23NO3.HCl","Hydrochloride","ALO4943A,KW4679","Cl.CN(C)CC\\C=C/1C2=C(COC3=C1C=C(CC(O)=O)C=C3)C=CC=C2",{"v":0.92,"d":"0.920"},2,0,5]
["S2496","Ozagrel","b9","L4000-04","in 10mM DMSO","P450 (e.g. CYP17),Prostaglandin Receptor","GPCR & G Protein","Ozagrel (OKY-046) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.",228.25,"82571-53-7",{"v":46,"d":"46.00"},201.53,"<1","N/A","http://selleckchem.com/products/Ozagrel.html","C13H12N2O2","free base","OKY-046","OC(=O)/C=C/C1=CC=C(C[N]2C=CN=C2)C=C1",1.604,2,0,4]
["S2497","Pancuronium dibromide","c9","L4000-04","in 10mM DMSO","AChR","Neuronal Signaling","Pancuronium dibromide(Pavulon) is a competitive nicotinic acetylcholine receptor antagonist, used as a muscle relaxant.",732.67,"15500-66-0",{"v":100,"d":"100.00"},136.49,{"v":100,"d":"100.00"},136.49,"http://selleckchem.com/products/Pancuronium-bromide(Pavulon).html","C35H60N2O4.2Br","di-quaternary-N bromide salt","Pavulon","[Br-].[Br-].CC(=O)OC1CC2CCC3C(CCC4(C)C3CC(C4OC(C)=O)[N+]5(C)CCCCC5)C2(C)CC1[N+]6(C)CCCCC6",-2.043,4,0,6]
["S2499","Phenoxybenzamine HCl","d9","L4000-04","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Phenoxybenzamine HCl (NSC 37448, NCI-c01661) is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.",{"v":340.3,"d":"340.30"},"63-92-3",{"v":68,"d":"68.00"},199.82,{"v":17,"d":"17.00"},49.96,"http://selleckchem.com/products/Phenoxybenzamine-hydrochloride.html","C18H22ClNO.HCl","HCl","NSC 37448, NCI-c01661","Cl.CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2",{"v":4.96,"d":"4.960"},1,0,8]
["S2500","Propafenone HCl","e9","L4000-04","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Propafenone HCl is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias.",{"v":377.9,"d":"377.90"},"34183-22-7",{"v":69,"d":"69.00"},182.59,"<1","N/A","http://selleckchem.com/products/Propafenone(Rytmonorm).html","C21H27NO3.HCl","Hydrochloride","N/A","CCCNCC(O)COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2",3.673,2,2,11]
["S2502","Quinine HCl Dihydrate","f9","L4000-04","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Quinine HCl Dihydrate is a white crystalline K+ channel blocker, used to treat malaria.",396.91,"6119-47-7",{"v":79,"d":"79.00"},199.04,{"v":43,"d":"43.00"},108.34,"http://selleckchem.com/products/Quinine-hydrochloride-dihydrate.html","C20H24N2O2.HCl.2H2O","Hydrochloride dihydrate","N/A","O.O.Cl.COC1=CC2=C(C=C1)N=CC=C2C(O)C3CC4CCN3CC4C=C",2.701,2,1,4]
["S2503","Racecadotril","g9","L4000-04","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","Racecadotril (Acetorphan) is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 μM.",385.48,"81110-73-8",{"v":22,"d":"22.00"},57.07,"<1","N/A","http://selleckchem.com/products/Racecadotril(Acetorphan).html","C21H23NO4S","free base","Acetorphan","CC(=O)SCC(CC1=CC=CC=C1)C(=O)NCC(=O)OCC2=CC=CC=C2",3.128,4,1,11]
["S2505","Rosiglitazone (BRL-49653) maleate","h9","L4000-04","in 10mM DMSO","Autophagy,Ferroptosis,PPAR,TRP Channel","Metabolism","Rosiglitazone maleate (BRL-49653C), a member of the thiazolidinedione class of antihyperglycaemic agents, is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-γ (PPAR-γ) with IC50 of 42 nM. Rosiglitazone maleate also modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis.",{"v":473.5,"d":"473.50"},"155141-29-0",{"v":94,"d":"94.00"},198.52,"<1","N/A","http://selleckchem.com/products/Rosiglitazone-maleate.html","C18H19N3O3S.C4H4O4","Maleate","BRL-49653C","CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C3=NC=CC=C3.OC(=O)\\C=C/C(O)=O",3.307,6,1,9]
["S2508","Scopolamine (LSM-4015) HBr","a10","L4000-04","in 10mM DMSO","AChR","Neuronal Signaling","Scopolamine HBr (LSM-4015,NSC 61806,(-)-Scopolamine hydrobromide, Hyoscine hydrobromide, Scopine hydrobromide) is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55.3 nM.",384.26,"114-49-8",{"v":76,"d":"76.00"},197.78,{"v":76,"d":"76.00"},197.78,"http://selleckchem.com/products/Scopolamine-hydrobromide.html","C17H21NO4.HBr","Hydrobromide","LSM-4015,NSC 61806,(-)-Scopolamine hydrobromide, Hyoscine hydrobromide, Scopine hydrobromide","Br.CN1C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",1.314,3,1,5]
["S2509","Sotalol HCl","b10","L4000-04","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Sotalol(MJ-1999)  is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 μM.",308.82,"959-24-0",{"v":61,"d":"61.00"},197.53,{"v":61,"d":"61.00"},197.53,"http://selleckchem.com/products/Sotalol-hydrochloride(Betapace).html","C12H20N2O3S.HCl","Hydrochloride","MJ-1999","Cl.CC(C)NCC(O)C1=CC=C(N[S](C)(=O)=O)C=C1",0.876,2,3,6]
["S2512","Tenoxicam","c10","L4000-04","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Tenoxicam(Ro-12-0068) is a good HO. radicals scavenger with an IC50 of 56.7 μM.",337.38,"59804-37-4",{"v":68,"d":"68.00"},201.55,"<1","N/A","http://selleckchem.com/products/Tenoxicam(Mobiflex).html","C13H11N3O4S2","free base","Ro-12-0068","CN1C(=C(O)C2=C(C=CS2)[S]1(=O)=O)C(=O)NC3=CC=CC=N3",0.454,4,2,2]
["S2516","Xylazine HCl","d10","L4000-04","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Xylazine(BAY 1470 hydrochloride) is an α2-Adrenergic receptor agonist, used as a sedative and muscle relaxant.",256.79,"23076-35-9",{"v":50,"d":"50.00"},194.71,{"v":12,"d":"12.00"},46.73,"http://selleckchem.com/products/Xylazine(Rompun).html","C12H16N2S.HCl","Hydrochloride","BAY 1470 hydrochloride","Cl.CC1=C(NC2=NCCCS2)C(=CC=C1)C",3.647,1,1,2]
["S2517","Maprotiline HCl","e10","L4000-04","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Maprotiline HCl is a selective noradrenalin re-uptake inhibitor, used in the treatment of depression.",313.86,"10347-81-6",{"v":63,"d":"63.00"},200.73,"<1","N/A","http://selleckchem.com/products/Maprotiline-hydrochloride.html","C20H23N.HCl","Hydrochloride","N/A","Cl.CNCCCC12CCC(C3=CC=CC=C13)C4=C2C=CC=C4",4.498,0,1,4]
["S2519","Naphazoline HCl","f10","L4000-04","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Naphazoline HCl is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.",246.74,"550-99-2",{"v":17,"d":"17.00"},{"v":68.9,"d":"68.90"},{"v":49,"d":"49.00"},198.59,"http://selleckchem.com/products/Naphazoline-hydrochloride-Naphcon.html","C14H14N2.HCl","Hydrochloride","N/A","Cl.C1CN=C(CC2=C3C=CC=CC3=CC=C2)N1",2.442,1,1,2]
["S2521","Epinephrine bitartrate","g10","L4000-04","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Epinephrine bitartrate (Adrenalinium) is an alpha- and beta-adrenergic receptor stimulator.",333.29,"51-42-3",{"v":67,"d":"67.00"},201.03,{"v":67,"d":"67.00"},201.03,"http://selleckchem.com/products/Epinephrine-bitartrate-Adrenalinium.html","C9H13NO3.C4H6O6","tartrate","Adrenalinium","CNCC(O)C1=CC(=C(O)C=C1)O.OC(C(O)C(O)=O)C(O)=O",-3.996,2,6,6]
["S2524","Phenytoin Sodium","h10","L4000-04","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Phenytoin Sodium (Aleviatin, Diphenylhydantoin sodium, Eptoin, Phenytoin soluble, Prompt; Phenytek,Dilantin sodium, Diphantoine) is an inactive voltage-gated sodium channel stabilizer.",274.25,"630-93-3",{"v":32,"d":"32.00"},116.68,{"v":3,"d":"3.00"},10.94,"http://selleckchem.com/products/Phenytoin-sodium-Dilantin.html","C15H11N2NaO2","Sodium Salt","Aleviatin, Diphenylhydantoin sodium, Eptoin, Phenytoin soluble, Prompt,Phenytek,Dilantin sodium, Diphantoine","[Na+].[O-]C1=NC(=O)C(N1)(C2=CC=CC=C2)C3=CC=CC=C3",2.084,2,1,2]
["S2525","Phenytoin","a11","L4000-04","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Phenytoin (Di-Hydan, Dihycon, Dilabid, Diphedan, Diphenat, Diphenylan, Diphenylhydantoin, Hydantol, Lehydan, NSC 8722) is an inactive voltage-gated sodium channel stabilizer.",252.27,"57-41-0",{"v":50,"d":"50.00"},{"v":198.2,"d":"198.20"},"<1","N/A","http://selleckchem.com/products/Phenytoin-Lepitoin.html","C15H12N2O2","Free Base","Di-Hydan, Dihycon, Dilabid, Diphedan, Diphenat, Diphenylan, Diphenylhydantoin, Hydantol, Lehydan, NSC 8722","O=C1NC(=O)C(N1)(C2=CC=CC=C2)C3=CC=CC=C3",2.105,2,2,2]
["S2529","Dopamine HCl","b11","L4000-04","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Dopamine HCl(ASL279, NSC 173182) is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.",189.64,"62-31-7",{"v":38,"d":"38.00"},200.38,{"v":38,"d":"38.00"},200.38,"http://selleckchem.com/products/Dopamine-hydrochloride-Inotropin.html","C8H11NO2.HCl","Hydrochloride","ASL279, NSC 173182","Cl.NCCC1=CC(=C(O)C=C1)O",1.155,0,3,2]
["S2531","Asaraldehyde","c11","L4000-04","in 10mM DMSO","COX","Neuronal Signaling","Asaraldehyde (Asaronaldehyde) is a natural COX-2 inhibitor, exhibiting 17-fold selectivity over COX-1.",{"v":196.2,"d":"196.20"},"4460-86-0",{"v":39,"d":"39.00"},198.78,"<1","N/A","http://selleckchem.com/products/Asaraldehyde-Asaronaldehyde.html","C10H12O4","free base","Asaronaldehyde","COC1=C(OC)C=C(C=O)C(=C1)OC",{"v":1.54,"d":"1.540"},4,0,4]
["S2533","Ritodrine HCl","d11","L4000-04","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Ritodrine HCl (NSC 291565,DU 21220, Ritodrine) is a hydrochloride salt of ritodrine which is a β-2 adrenergic receptor agonist.",323.81,"23239-51-2",{"v":65,"d":"65.00"},200.73,{"v":65,"d":"65.00"},200.73,"http://selleckchem.com/products/Ritodrine-hydrochloride-Yutopar.html","C17H21NO3.HCl","Hydrochloride","NSC 291565,DU 21220, Ritodrine","Cl.CC(NCCC1=CC=C(O)C=C1)C(O)C2=CC=C(O)C=C2",3.037,0,4,6]
["S2535","Econazole nitrate","e11","L4000-04","in 10mM DMSO","Calcium Channel,Fungal","Transmembrane Transporters","Econazole Nitrate (NSC 243115,Spectazole) is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus.",{"v":444.7,"d":"444.70"},"24169-02-6",{"v":89,"d":"89.00"},200.13,"<1","N/A","http://selleckchem.com/products/Econazole-nitrate-Spectazole.html","C18H15Cl3N2O.HNO3","Nitrate","NSC 243115,Spectazole","O[N+]([O-])=O.ClC1=CC=C(COC(C[N]2C=CN=C2)C3=CC=C(Cl)C=C3Cl)C=C1",3.722,2,0,6]
["S2541","Clomipramine HCl","f11","L4000-04","in 10mM DMSO","Serotonin Transporter","Neuronal Signaling","Clomipramine HCl(Anafranil) is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively.",351.31,"17321-77-6",{"v":70,"d":"70.00"},199.25,{"v":70,"d":"70.00"},199.25,"http://selleckchem.com/products/Clomipramine-hydrochloride-Anafranil.html","C19H23ClN2.HCl","Hydrochloride","Anafranil","Cl.CN(C)CCCN1C2=C(CCC3=C1C=C(Cl)C=C3)C=CC=C2",5.434,0,0,4]
["S2545","Scopine","g11","L4000-04","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Scopine(6,7-Epoxytropine) is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.",155.19,"498-45-3",{"v":31,"d":"31.00"},199.76,"<1","N/A","http://selleckchem.com/products/scopine.html","C8H13NO2","free base","6,7-Epoxytropine","CN1C2CC(O)CC1C3OC23",-0.627,1,1,0]
["S2547","Tiotropium Bromide hydrate","h11","L4000-04","in 10mM DMSO","AChR","Neuronal Signaling","Tiotropium Bromide hydrate (BA 679BR) is a monohydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a muscarinic receptor antagonist.",490.43,"139404-48-1",{"v":8,"d":"8.00"},16.31,"<1","N/A","http://selleckchem.com/products/Tiotropium-Bromide-hydrate.html","C19H22NO4S2.Br.xH2O","quaternary-N bromide salt&hydr","BA 679BR","O.[Br-].C[N+]1(C)C2CC(CC1C3OC23)OC(=O)C(O)(C4=CC=CS4)C5=CC=CS5",-1.727,3,0,5]
["S2549","Trospium chloride","a2","L4000-05","in 10mM DMSO","AChR","Neuronal Signaling","Trospium chloride  is a competitive muscarinic cholinergic receptor antagonist.",427.96,"10405-02-4",{"v":41,"d":"41.00"},{"v":95.8,"d":"95.80"},{"v":86,"d":"86.00"},200.95,"http://selleckchem.com/products/Trospium-chloride-Sanctura.html","C25H30NO3.Cl","quaternary-N chloride salt","N/A","[Cl-].OC(C(=O)OC1CC2CCC(C1)[N+]23CCCC3)(C4=CC=CC=C4)C5=CC=CC=C5",-0.324,2,0,5]
["S2552","Azelastine HCl","b2","L4000-05","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Azelastine HCl is a potent, second-generation, selective, histamine receptor antagonist, used in the treatment of rhinitis.",418.36,"79307-93-0",{"v":28,"d":"28.00"},66.93,{"v":35,"d":"35.00"},83.66,"http://selleckchem.com/products/azelastine.html","C22H24ClN3O.HCl","Hydrochloride","N/A","Cl.CN1CCCC(CC1)N2N=C(CC3=CC=C(Cl)C=C3)C4=CC=CC=C4C2=O",4.476,2,0,3]
["S2556","Rosiglitazone (BRL 49653)","c2","L4000-05","in 10mM DMSO","Autophagy,Ferroptosis,PPAR,TRP Channel","Metabolism","Rosiglitazone (BRL 49653) is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively. Rosiglitazone is a pure ligand of PPAR-gamma, and has no PPAR-alpha-binding action. Rosiglitazone modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis.",357.43,"122320-73-4",{"v":71,"d":"71.00"},198.64,"<1","N/A","http://selleckchem.com/products/Rosiglitazone-Avandia.html","C18H19N3O3S","Free Base","BRL 49653","CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C3=CC=CC=N3",3.268,4,1,7]
["S2559","Cortisone acetate","d2","L4000-05","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Cortisone acetate (Cortone, NSC 49420) is an acetate salt form of cortisone that is a steroid hormone and a glucocorticoid.",402.48,"50-04-4",{"v":7,"d":"7.00"},17.39,"<1","N/A","http://selleckchem.com/products/Cortisone-acetate-Cortone.html","C23H30O6","free base","Cortone,NSC 49420","CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3C(=O)CC12C",1.619,5,0,4]
["S2566","Isoprenaline (NCI-C55630) HCl","e2","L4000-05","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Isoprenaline HCl (NCI-c55630,Isoproterenol hydrochloride) is a non-selective beta-adrenergic receptor agonist, used for the treatment of bradycardia and heart block.",247.72,"51-30-9",{"v":50,"d":"50.00"},201.84,{"v":50,"d":"50.00"},201.84,"http://selleckchem.com/products/Isoprenaline-hydrochloride.html","C11H17NO3.HCl","Hydrochloride","NCI-c55630,Isoproterenol hydrochloride","Cl.CC(C)NCC(O)C1=CC=C(O)C(=C1)O",1.481,0,4,4]
["S2567","Medroxyprogesterone acetate (NSC-26386)","f2","L4000-05","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Medroxyprogesterone acetate (MPA, NSC-26386, Medroxyprogesterone 17-acetate, Farlutin) is a synthetic progestin and act as a potent progesterone receptor agonist, used to treat abnormal menstruation or irregular vaginal bleeding.",386.52,"71-58-9",{"v":12,"d":"12.00"},31.05,"<1","N/A","http://selleckchem.com/products/Medroxyprogesterone-acetate.html","C24H34O4","Free Base","MPA, NSC-26386, Medroxyprogesterone 17-acetate, Farlutin","CC1CC2C(CCC3(C)C2CCC3(OC(C)=O)C(C)=O)C4(C)CCC(=O)C=C14",3.755,4,0,3]
["S2569","Phenylephrine (NCI-C55641) HCl","g2","L4000-05","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Phenylephrine HCl (NCI-c55641,Phenylephrine hydrochloride,(R)-(-)-Phenylephrine hydrochloride, L-Phenylephrine hydrochloride) is a selective α1-adrenergic receptor agonist, used primarily as a decongestant.",203.67,"61-76-7",{"v":41,"d":"41.00"},201.31,{"v":41,"d":"41.00"},201.31,"http://selleckchem.com/products/Phenylephrine-hydrochloride.html","C9H13NO2.HCl","Hydrochloride","NCI-c55641,Phenylephrine hydrochloride,(R)-(-)-Phenylephrine hydrochloride, L-Phenylephrine hydrochloride","Cl.CNCC(O)C1=CC(=CC=C1)O",0.997,0,3,3]
["S2570","Prednisolone Acetate","h2","L4000-05","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Prednisolone Acetate (Omnipred,Prednisolone-21-acetate) is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant agent.",402.48,"52-21-1",{"v":81,"d":"81.00"},201.25,"<1","N/A","http://selleckchem.com/products/Prednisolone-acetate-Omnipred.html","C23H30O6","free base","Omnipred,Prednisolone-21-acetate","CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)C=CC4(C)C3C(O)CC12C",1.639,4,1,4]
["S2573","Tetracaine HCl","a3","L4000-05","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Tetracaine HCl (Amethocaine hydrochloride) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.",300.82,"136-47-0",{"v":60,"d":"60.00"},199.45,{"v":60,"d":"60.00"},199.45,"http://selleckchem.com/products/tetracaine-hydrochloride-pontocaine.html","C15H24N2O2.HCl","Hydrochloride","Amethocaine hydrochloride","Cl.CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C",3.343,2,1,9]
["S2576","Xylometazoline HCl","b3","L4000-05","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM.",280.84,"1218-35-5",{"v":27,"d":"27.00"},96.14,{"v":56,"d":"56.00"},{"v":199.4,"d":"199.40"},"http://selleckchem.com/products/xylometazoline-hcl.html","C16H24N2.HCl","HCl","N/A","Cl.CC1=C(CC2=NCCN2)C(=CC(=C1)C(C)(C)C)C",3.906,1,1,3]
["S2577","Phenacetin","c3","L4000-05","in 10mM DMSO","COX","Neuronal Signaling","Phenacetin (Acetophenetidin) is a non-opioid analgesic without anti-inflammatory properties.",179.22,"62-44-2",{"v":36,"d":"36.00"},200.87,"<1","N/A","http://selleckchem.com/products/phenacetin.html","C10H13NO2","free base","Acetophenetidin","CCOC1=CC=C(NC(C)=O)C=C1",1.282,2,1,3]
["S2584","Clobetasol propionate","d3","L4000-05","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Clobetasol propionate (CGP9555, CCl 4725) is an anti-inflammatory corticosteroid used to treat various skin disorders.",466.97,"25122-46-7",{"v":93,"d":"93.00"},199.16,"<1","N/A","http://selleckchem.com/products/clobetasol-propionate.html","C25H32ClFO5","free base","CGP9555, CCl 4725","CCC(=O)OC1(C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)CCl",3.958,4,1,5]
["S2585","Brompheniramine hydrogen maleate","e3","L4000-05","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Brompheniramine hydrogen maleate(Brompheniramine maleate) is a histamine H1 receptors antagonist.",435.31,"980-71-2",{"v":87,"d":"87.00"},199.86,{"v":46,"d":"46.00"},105.67,"http://selleckchem.com/products/brompheniramine.html","C16H19BrN2.C4H4","Maleate","Brompheniramine maleate","CN(C)CCC(C1=CC=C(Br)C=C1)C2=CC=CC=N2.OC(=O)\\C=C/C(O)=O",0.784,3,0,7]
["S2590","Pioglitazone (AD-4833)","f3","L4000-05","in 10mM DMSO","PPAR","Metabolism","Pioglitazone (AD-4833, U 72107) is a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, used to treat diabetes; A weak activator for full-length hPPARα, but not full-length hPPARδ.",356.44,"111025-46-8",{"v":10,"d":"10.00"},28.06,"<1","N/A","https://www.selleckchem.com/products/pioglitazone.html","C19H20N2O3S","Free Base","U 72107","CCC1=CC=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)N=C1",3.907,4,1,7]
["S2594","Pramiracetam","g3","L4000-05","in 10mM DMSO","Others","Others","Pramiracetam (CI-879,Pramistar) is a more potent nootropic drug derived from piracetam.",269.38,"68497-62-1",{"v":54,"d":"54.00"},200.46,"<1","N/A","http://selleckchem.com/products/pramiracetam.html","C14H27N3O2","free base","CI-879,Pramistar","CC(C)N(CCNC(=O)CN1CCCC1=O)C(C)C",0.486,2,1,7]
["S2602","Acemetacin","h3","L4000-05","in 10mM DMSO","COX","Neuronal Signaling","Acemetacin (K-708,TVX 1322) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.",415.82,"53164-05-9",{"v":83,"d":"83.00"},199.61,"<1","N/A","http://selleckchem.com/products/acemetacin-emflex.html","C21H18ClNO6","free base","K-708,TVX 1322","COC1=CC2=C(C=C1)[N](C(=C2CC(=O)OCC(O)=O)C)C(=O)C3=CC=C(Cl)C=C3",3.942,5,0,7]
["S2603","Tioxolone","a4","L4000-05","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Tioxolone(Thioxolone) is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM.",168.17,"4991-65-5",{"v":34,"d":"34.00"},202.18,"<1","N/A","http://selleckchem.com/products/tioxolone.html","C7H4O3S","free base","Thioxolone","OC1=CC=C2SC(=O)OC2=C1",2.303,2,1,0]
["S2605","Idebenone","b4","L4000-05","in 10mM DMSO","ROS","Immunology & Inflammation","Idebenone (CV-2619) is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant.",338.44,"58186-27-9",{"v":68,"d":"68.00"},200.92,"<1","N/A","http://selleckchem.com/products/idebenone.html","C19H30O5","free base","CV-2619","COC1=C(OC)C(=O)C(=C(C)C1=O)CCCCCCCCCCO",3.836,4,1,12]
["S2606","Mifepristone (RU486)","c4","L4000-05","in 10mM DMSO","Apoptosis related,Autophagy,Bcl-2,Estrogen/progestogen Receptor,Glucocorticoid Receptor","Endocrinology & Hormones","Mifepristone (RU486, C-1073, RU 38486, Mifegyne) is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.",429.59,"84371-65-3",{"v":85,"d":"85.00"},197.86,"<1","N/A","http://selleckchem.com/products/Mifepristone(Mifeprex).html","C29H35NO2","free base","RU486, C-1073, RU 38486, RU-486, Mifegyne","CC#CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C(CC12C)C5=CC=C(C=C5)N(C)C",5.655,1,0,3]
["S2607","Buflomedil HCl","d4","L4000-05","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Buflomedil HCl(NSC 759291) is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease;  A nonselective alpha adrenergic receptor inhibitor.",343.85,"35543-24-9",{"v":31,"d":"31.00"},90.16,{"v":69,"d":"69.00"},200.67,"http://selleckchem.com/products/auflomedil-hcl.html","C17H25NO4.HCl","Hydrochloride","NSC 759291","Cl.COC1=CC(=C(C(=O)CCCN2CCCC2)C(=C1)OC)OC",2.939,4,0,8]
["S2608","Fluocinonide","e4","L4000-05","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Fluocinonide (Vanos,nsc 101791) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema.",494.52,"356-12-7",{"v":99,"d":"99.00"},200.19,"<1","N/A","http://selleckchem.com/products/Fluocinonide(Vanos).html","C26H32F2O7","free base","Vanos,nsc 101791","CC(=O)OCC(=O)C12OC(C)(C)OC1CC3C4CC(F)C5=CC(=O)C=CC5(C)C4(F)C(O)CC23C",1.374,6,1,4]
["S2614","Arecoline HBr","f4","L4000-05","in 10mM DMSO","AChR","Neuronal Signaling","Arecoline(NSC-31750) is a muscarinic acetylcholine receptor agonist.",236.11,"300-08-3",{"v":47,"d":"47.00"},199.06,{"v":47,"d":"47.00"},199.06,"https://www.selleckchem.com/products/arecoline-hbr.html","C8H13NO2.HBr","HBr","NSC-31750","Br.COC(=O)C1=CCCN(C)C1",1.234,2,0,2]
["S2615","Noradrenaline bitartrate monohydrate","g4","L4000-05","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Noradrenaline bitartrate monohydrate (Levophed) is a direct alpha-adrenergic receptors stimulator.",337.28,"108341-18-0",{"v":64,"d":"64.00"},189.75,{"v":64,"d":"64.00"},189.75,"http://selleckchem.com/products/noradrenaline-bitartrate-monohydrate-levophed.html","C8H11NO3.C4H6O6.H2O","bitartrate monohydrate","Levophed","O.NCC(O)C1=CC(=C(O)C=C1)O.OC(C(O)C(O)=O)C(O)=O",-4.409,2,6,5]
["S2629","PNU-120596","h4","L4000-05","in 10mM DMSO","AChR","Neuronal Signaling","PNU-120596 (Nsc 216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.",311.72,"501925-31-1",{"v":62,"d":"62.00"},{"v":198.9,"d":"198.90"},"<1","N/A","http://selleckchem.com/products/pnu120596.html","C13H14ClN3O4","free base","Nsc 216666","COC1=CC(=C(NC(=O)NC2=NOC(=C2)C)C=C1Cl)OC",2.293,5,2,4]
["S2631","URB597","a5","L4000-05","in 10mM DMSO","FAAH","Metabolism","URB597 (KDS-4103) is a potent, orally bioavailable FAAH inhibitor with IC50 of 4.6 nM, with no activity on other cannabinoid-related targets. Phase 1.",{"v":338.4,"d":"338.40"},"546141-08-6",{"v":68,"d":"68.00"},200.95,"<1","N/A","http://selleckchem.com/products/urb597.html","C20H22N2O3","free base","KDS-4103","NC(=O)C1=CC(=CC=C1)C2=CC=CC(=C2)OC(=O)NC3CCCCC3",3.972,3,2,5]
["S2660","MK-0752","b5","L4000-05","in 10mM DMSO","Beta Amyloid,Secretase","Proteases","MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM. Phase 1/2.",{"v":442.9,"d":"442.90"},"471905-41-6",{"v":89,"d":"89.00"},200.95,"<1","N/A","http://selleckchem.com/products/mk-0752.html","C21H21ClF2O4S","free base","N/A","OC(=O)CCC1CCC(CC1)(C2=C(F)C=CC(=C2)F)[S](=O)(=O)C3=CC=C(Cl)C=C3",5.615,3,0,6]
["S2663","WAY-100635 Maleate","c5","L4000-05","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","WAY-100635 Maleate is a potent and selective 5-HT receptor antagonist with IC50 of 0.95 nM.",538.64,"1092679-51-0",{"v":85,"d":"85.00"},{"v":157.8,"d":"157.80"},"<1","N/A","http://selleckchem.com/products/way-100635.html","C25H34N4O2.C4H4O4","Maleate","N/A","COC1=C(C=CC=C1)N2CCN(CC2)CCN(C(=O)C3CCCCC3)C4=NC=CC=C4.OC(=O)\\C=C/C(O)=O",1.427,5,0,9]
["S2666","PF-3845","d5","L4000-05","in 10mM DMSO","FAAH","Metabolism","PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.",456.46,"1196109-52-0",{"v":91,"d":"91.00"},199.36,"<1","N/A","http://selleckchem.com/products/pf-3845.html","C24H23F3N4O2","free base","N/A","FC(F)(F)C1=CN=C(OC2=CC(=CC=C2)CC3CCN(CC3)C(=O)NC4=CN=CC=C4)C=C1",{"v":4.55,"d":"4.550"},4,1,6]
["S2677","BRL-15572 Dihydrochloride","e5","L4000-05","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","BRL-15572 is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor.",479.87,"193611-72-2",{"v":96,"d":"96.00"},200.05,"<1","N/A","https://www.selleckchem.com/products/brl-15572-dihydrochloride.html","C25H27ClN2O.2HCl","Dihydrochloride","N/A","Cl.Cl.OC(CN1CCN(CC1)C2=CC(=CC=C2)Cl)C(C3=CC=CC=C3)C4=CC=CC=C4",6.123,0,1,6]
["S2687","Mardepodect (PF-2545920)","f5","L4000-05","in 10mM DMSO","PDE","Metabolism","Mardepodect (PF-2545920) is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM, with >1000-fold selectivity over the PDE.",392.45,"1292799-56-4",{"v":78,"d":"78.00"},198.75,"<1","N/A","http://selleckchem.com/products/pf-2545920.html","C25H20N4O","free base","N/A","C[N]1C=C(C2=CC=NC=C2)C(=N1)C3=CC=C(OCC4=NC5=CC=CC=C5C=C4)C=C3",4.763,4,0,5]
["S2690","ADX-47273","g5","L4000-05","in 10mM DMSO","GluR","Neuronal Signaling","ADX47273 (BA 94673139) is a potent and specific mGlu5 positive allosteric modulator(PAM) with EC50 of 0.17 μM, showing no activity at other mGlu subtypes.",369.36,"851881-60-2",{"v":74,"d":"74.00"},200.35,"<1","N/A","http://selleckchem.com/products/adx-47273.html","C20H17F2N3O2","free base","BA 94673139","FC1=CC=C(C=C1)C(=O)N2CCCC(C2)C3=NC(=NO3)C4=CC=C(F)C=C4",3.577,4,0,3]
["S2691","BMY 7378 Dihydrochloride","h5","L4000-05","in 10mM DMSO","5-HT Receptor,Adrenergic Receptor","Neuronal Signaling","BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3.",458.42,"21102-95-4",{"v":92,"d":"92.00"},200.69,{"v":92,"d":"92.00"},200.69,"http://selleckchem.com/products/bmy-7378.html","C22H31N3O3.2HCl","Dihydrochloride","N/A","Cl.Cl.COC1=CC=CC=C1N2CCN(CC2)CCN3C(=O)CC4(CCCC4)CC3=O",3.384,3,0,5]
["S2695","Nepicastat (SYN-117) HCl","a6","L4000-05","in 10mM DMSO","Hydroxylase","Metabolism","Nepicastat (SYN-117) HCl is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. Phase 2.",331.81,"170151-24-3",{"v":66,"d":"66.00"},198.91,"<1","N/A","http://selleckchem.com/products/nepicastat-hydrochloride.html","C14H15F2N3S.HCl","Hydrochloride","N/A","Cl.NCC1=CNC(=S)N1C2CCC3=C(F)C=C(F)C=C3C2",3.008,0,2,2]
["S2698","RS-127445","b6","L4000-05","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","RS-127445 (MT500) is a selective 5-HT2B receptor antagonist with pKi of 9.5 and pIC50 of 10.4, exhibits >1000-fold selectivity against other 5-HT receptors.",281.33,"199864-87-4",{"v":56,"d":"56.00"},199.05,"<1","N/A","http://selleckchem.com/products/rs-127445.html","C17H16FN3","free base","MT500","CC(C)C1=NC(=NC(=C1)C2=C3C=CC=CC3=C(F)C=C2)N",4.298,2,1,2]
["S2711","Dibenzazepine (YO-01027)","c6","L4000-05","in 10mM DMSO","Notch,Secretase","Proteases","Dibenzazepine (YO-01027, DBZ) is a dipeptidic γ-secretase inhibitor with IC50 of 2.6 nM and 2.9 nM  in cell-free assays for APPL and Notch cleavage, respectively.",463.48,"209984-56-5",{"v":92,"d":"92.00"},{"v":198.5,"d":"198.50"},"<1","N/A","http://selleckchem.com/products/yo-01027.html","C26H23F2N3O3","free base","DBZ","CC(NC(=O)CC1=CC(=CC(=C1)F)F)C(=O)NC2C(=O)N(C)C3=C(C=CC=C3)C4=C2C=CC=C4",3.277,3,2,5]
["S2714","LY411575","d6","L4000-05","in 10mM DMSO","Apoptosis related,Notch,Secretase","Proteases","LY411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), also inhibits Notch cleavage with IC50 of 0.39 nM in APP or NΔE expressing HEK293 cells. LY411575 induces apoptosis.",479.48,"209984-57-6",{"v":95,"d":"95.00"},198.13,"<1","N/A","http://selleckchem.com/products/ly-411575.html","C26H23F2N3O4","free base","N/A","CC(NC(=O)C(O)C1=CC(=CC(=C1)F)F)C(=O)NC2C(=O)N(C)C3=C(C=CC=C3)C4=C2C=CC=C4",2.625,3,3,5]
["S2721","Nilvadipine","e6","L4000-05","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Nilvadipine (ARC029, FR34235,FK235) is a potent calcium channel blocker with an IC50 of 0.03 nM.",385.37,"75530-68-6",{"v":77,"d":"77.00"},199.81,"<1","N/A","http://selleckchem.com/products/nilvadipine-arc029.html","C19H19N3O6","free base","ARC029, FR34235,FK235","COC(=O)C1=C(NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OC(C)C)C)C#N",2.087,4,1,7]
["S2722","JTC-801","f6","L4000-05","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","JTC-801 is a selective opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM, weakly inhibits receptors δ, κ, and μ.",447.96,"244218-51-7",{"v":90,"d":"90.00"},200.91,"<1","N/A","http://selleckchem.com/products/jtc-801.html","C26H25N3O2.HCl","Hydrochloride","N/A","Cl.CCC1=CC=C(OCC2=CC=CC=C2C(=O)NC3=CC4=C(C=C3)N=C(C)C=C4N)C=C1",5.228,3,2,6]
["S2773","SB705498","g6","L4000-05","in 10mM DMSO","TRP Channel","Transmembrane Transporters","SB705498 is a TRPV1 antagonist for hTRPV1, antagonizes capsaicin, acid, and heat activation of TRPV1 with IC50 of 3 nM, 0.1 nM and 6 nM, shows a degree of voltage dependence, exhibits >100-fold selectivity for TRPV1 over TRPM8. Phase 2.",429.23,"501951-42-4",{"v":86,"d":"86.00"},200.36,"<1","N/A","http://selleckchem.com/products/sb705498.html","C17H16BrF3N4O","free base","N/A","FC(F)(F)C1=CN=C(C=C1)N2CCC(C2)NC(=O)NC3=CC=CC=C3Br",3.745,2,2,4]
["S2778","GW842166X","h6","L4000-05","in 10mM DMSO","Cannabinoid Receptor","GPCR & G Protein","GW842166X is a potent and highly selective agonist of cannabinoid receptor CB2 receptor with EC50 of 63 nM, shows no significant activity at CB1 receptor. Phase 2.",449.25,"666260-75-9",{"v":20,"d":"20.00"},44.52,"<1","N/A","http://selleckchem.com/products/gw-842166x.html","C18H17Cl2F3N4O2","free base","N/A","FC(F)(F)C1=NC(=NC=C1C(=O)NCC2CCOCC2)NC3=CC=C(Cl)C=C3Cl",4.449,4,2,6]
["S2785","A-803467","a7","L4000-05","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","A-803467 is a selective NaV1.8 channel blocker with IC50 of 8 nM, blocks tetrodotoxin-resistant currents, exhibits >100-fold selectivity against human NaV1.2, NaV1.3, NaV1.5, and NaV1.7.",357.79,"944261-79-4",{"v":72,"d":"72.00"},201.24,"<1","N/A","http://selleckchem.com/products/a-803467.html","C19H16ClNO4","free base","N/A","COC1=CC(=CC(=C1)NC(=O)C2=CC=C(O2)C3=CC=C(Cl)C=C3)OC",4.451,4,1,5]
["S2790","Istradefylline","b7","L4000-05","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","Istradefylline (KW-6002) is a selective adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. Phase 3.",384.43,"155270-99-8",{"v":6,"d":"6.00"},15.61,"<1","N/A","http://selleckchem.com/products/istradefylline-kw-6002.html","C20H24N4O4","free base","KW-6002","CCN1C(=O)N(CC)C2=C([N](C)C(=N2)\\C=C\\C3=CC=C(OC)C(=C3)OC)C1=O",2.957,5,0,6]
["S2795","VU 0357121","c7","L4000-05","in 10mM DMSO","GluR","Neuronal Signaling","VU0357121 is a novel positive allosteric modulator (PAM) of mGlu5 with EC50 of 33 nM, is inactive or very weakly antagonizing at other mGlu receptor subtypes.",305.32,"433967-28-3",{"v":61,"d":"61.00"},199.79,"<1","N/A","http://selleckchem.com/products/vu-0357121.html","C17H17F2NO2","free base","N/A","CCCCOC1=CC=C(C=C1)C(=O)NC2=C(F)C=C(F)C=C2",4.338,2,1,6]
["S2809","MPEP","d7","L4000-05","in 10mM DMSO","GluR","Neuronal Signaling","MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.",193.24,"96206-92-7",{"v":39,"d":"39.00"},201.82,"<1","N/A","http://selleckchem.com/products/mpep.html","C14H11N","free base","N/A","CC1=NC(=CC=C1)C#CC2=CC=CC=C2",3.499,1,0,2]
["S2813","Ciproxifan Maleate","e7","L4000-05","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Ciproxifan (FUB 359) is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes.",{"v":386.4,"d":"386.40"},"184025-19-2",{"v":54,"d":"54.00"},139.75,{"v":1,"d":"1.00"},2.59,"http://selleckchem.com/products/ciproxifan.html","C16H18N2O2.C4H4O4","Maleate","FUB 359","OC(=O)\\C=C/C(O)=O.O=C(C1CC1)C2=CC=C(OCCCC3=C[NH]C=N3)C=C2",2.605,5,1,9]
["S2816","Tyrphostin AG 879","f7","L4000-05","in 10mM DMSO","HER2","Protein Tyrosine Kinase","Tyrphostin AG 879 potently inhibits HER2/ErbB2 with IC50 of 1 μM, 100- and 500-fold higher selective to ErbB2 than PDGFR and EGFR.",316.46,"148741-30-4",{"v":36,"d":"36.00"},113.76,"<1","N/A","http://selleckchem.com/products/tyrphostin-ag-879-ag-879.html","C18H24N2OS","free base","AG 879","CC(C)(C)C1=C(O)C(=CC(=C1)/C=C(C#N)/C(N)=S)C(C)(C)C",4.565,0,2,4]
["S2819","AM251","g7","L4000-05","in 10mM DMSO","Cannabinoid Receptor","GPCR & G Protein","AM251 block the inhibitory effects of endocannabinoids and synthetic cannabinoid agonists on transmitter release through an action at presynaptic cannabinoid 1 receptors in brain.",555.24,"183232-66-8",{"v":40,"d":"40.00"},72.04,"<1","N/A","http://selleckchem.com/products/am251.html","C22H21Cl2IN4O","free base","N/A","CC1=C([N](N=C1C(=O)NN2CCCCC2)C3=CC=C(Cl)C=C3Cl)C4=CC=C(I)C=C4",6.527,2,1,4]
["S2823","Tideglusib (NP031112)","h7","L4000-05","in 10mM DMSO","COVID-19,GSK-3","PI3K/Akt/mTOR","Tideglusib (NP031112, NP-12) is an irreversible, non ATP-competitive GSK-3β inhibitor with IC50 of 60 nM in a cell-free assay; fails to inhibit kinases with a Cys homologous to Cys-199 located in the active site. Phase 2.",334.39,"865854-05-3",{"v":8,"d":"8.00"},23.92,"<1","N/A","http://selleckchem.com/products/tideglusib.html","C19H14N2O2S","free base","NP-12","O=C1SN(C(=O)N1CC2=CC=CC=C2)C3=C4C=CC=CC4=CC=C3",{"v":4.63,"d":"4.630"},2,0,3]
["S2828","JNJ-1661010","a8","L4000-05","in 10mM DMSO","FAAH","Metabolism","JNJ-1661010 (Takeda-25) is a potent and selective FAAH inhibitor with IC50 of 10 nM (rat) and 12 nM (human), exhibits >100-fold selectivity for FAAH-1 when compared to FAAH-2.",365.45,"681136-29-8",{"v":36,"d":"36.00"},98.51,"<1","N/A","http://selleckchem.com/products/jnj-1661010.html","C19H19N5OS","Free Base","Takeda-25","O=C(NC1=CC=CC=C1)N2CCN(CC2)C3=NC(=NS3)C4=CC=CC=C4",3.271,3,1,3]
["S2849","SB269970 HCl","b8","L4000-05","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","SB269970 HCl is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with pKi of 8.3, exhibits >50-fold selectivity against other receptors.",388.95,"261901-57-9",{"v":11,"d":"11.00"},28.28,"<1","N/A","http://selleckchem.com/products/sb-269970-hcl.html","C18H28N2O3S.HCl","Hydrochloride","N/A","Cl.CC1CCN(CC1)CCC2CCCN2[S](=O)(=O)C3=CC=CC(=C3)O",2.946,2,1,5]
["S2852","BRL-54443","c8","L4000-05","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","BRL 54443 is a 5-HT1E and 5-HT1F receptor agonist with pKi of 8.7 and 9.25, respectively, with a weak binding affinity for 5-HT1A, 5-HT1B, 5-HT1D receptors.",230.31,"57477-39-1",{"v":46,"d":"46.00"},199.73,"<1","N/A","http://selleckchem.com/products/brl-54443.html","C14H18N2O","free base","N/A","CN1CCC(CC1)C2=C[NH]C3=C2C=C(O)C=C3",2.572,0,2,1]
["S2854","BML-190","d8","L4000-05","in 10mM DMSO","Cannabinoid Receptor","GPCR & G Protein","BML-190 (IMMA) is a selective cannabinoid CB2 receptor inverse agonist with Ki of 435 nM, with 50-fold selectivity over CB1 receptor.",426.89,"2854-32-2",{"v":22,"d":"22.00"},51.54,"<1","N/A","http://selleckchem.com/products/bml-190.html","C23H23ClN2O4","free base","IMMA","COC1=CC2=C(C=C1)[N](C(=C2CC(=O)N3CCOCC3)C)C(=O)C4=CC=C(Cl)C=C4",3.707,4,0,4]
["S2855","MRS 2578","e8","L4000-05","in 10mM DMSO","P2 Receptor","Neuronal Signaling","MRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors.",472.67,"711019-86-2",{"v":42,"d":"42.00"},88.86,"<1","N/A","http://selleckchem.com/products/mrs-2578.html","C20H20N6S4","free base","N/A","S=C=NC1=CC=CC(=C1)NC(=S)NCCCCNC(=S)NC2=CC(=CC=C2)N=C=S",7.004,2,4,13]
["S2856","SB 271046 hydrochloride","f8","L4000-05","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","SB 271046 hydrochloride is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9, exhibits 200-fold greater selectivity over other 5-HT receptor subtypes.",488.45,"209481-24-3",{"v":40,"d":"40.00"},81.89,"<1","N/A","http://selleckchem.com/products/sb-271046.html","C20H22ClN3O3S2.HCl","hydrochloride","N/A","COC1=CC=C(N[S](=O)(=O)C2=C(C)C3=CC(=CC=C3S2)Cl)C=C1N4CCNCC4",4.403,3,2,5]
["S2857","(-)-Dizocilpine (MK 801) Maleate","g8","L4000-05","in 10mM DMSO","NMDAR","Neuronal Signaling","(-)-Dizocilpine (MK 801, Dizocilpine, C13737) Maleate is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.",337.37,"121917-57-5",{"v":67,"d":"67.00"},{"v":198.6,"d":"198.60"},"<1","N/A","http://selleckchem.com/products/--mk-801-maleate.html","C16H15N.C4H4O4","maleate","C13737","CC12NC(CC3=C1C=CC=C3)C4=C2C=CC=C4.OC(=O)\\C=C/C(O)=O",0.376,2,1,2]
["S2860","IEM 1754 2HBr","h8","L4000-05","in 10mM DMSO","GluR","Neuronal Signaling","IEM 1754 2HBr is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.",412.25,"162831-31-4",{"v":82,"d":"82.00"},198.91,{"v":82,"d":"82.00"},198.91,"http://selleckchem.com/products/iem-1754-dihydrobromide.html","C16H30N2.2HBr","DihydrobroMide","N/A","Br.Br.NCCCCCNC[C]12C[CH]3C[CH]([CH2]C([CH2]3)C1)C2",{"v":3.51,"d":"3.510"},0,2,7]
["S2861","CTEP (RO4956371)","a9","L4000-05","in 10mM DMSO","GluR","Neuronal Signaling","CTEP (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold selectivity over other mGlu receptors.",391.77,"871362-31-1",{"v":78,"d":"78.00"},{"v":199.1,"d":"199.10"},"<1","N/A","http://selleckchem.com/products/ctep.html","C19H13ClF3N3O","free base","N/A","CC1=NC(=C(C)[N]1C2=CC=C(OC(F)(F)F)C=C2)C#CC3=CC=NC(=C3)Cl",6.286,3,0,5]
["S2862","VU 0364770","b9","L4000-05","in 10mM DMSO","GluR","Neuronal Signaling","VU 0364770 is a positive allosteric modulator(PAM) of mGlu4 with EC50 of 1.1 μM, exhibits insignificant activity at 68 other receptors, including other mGlu subtypes.",232.67,"61350-00-3",{"v":47,"d":"47.00"},{"v":202,"d":"202.00"},"<1","N/A","http://selleckchem.com/products/vu-0364770.html","C12H9ClN2O","free base","N/A","ClC1=CC(=CC=C1)NC(=O)C2=NC=CC=C2",2.557,2,1,2]
["S2865","VUF 10166","c9","L4000-05","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower.",262.74,"155584-74-0",{"v":21,"d":"21.00"},79.93,"<1","N/A","http://selleckchem.com/products/vuf-10166.html","C13H15ClN4","free base","N/A","CN1CCN(CC1)C2=NC3=CC=CC=C3N=C2Cl",2.826,2,0,1]
["S2866","U-104","d9","L4000-05","in 10mM DMSO","Carbonic Anhydrase","Metabolism","U-104 (MST-104, NSC 213841, SLC-0111, WBI-5111) is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II.",309.32,"178606-66-1",{"v":62,"d":"62.00"},200.44,"<1","N/A","http://selleckchem.com/products/u-104.html","C13H12FN3O3S","free base","MST-104, NSC 213841, SLC-0111, WBI-5111","N[S](=O)(=O)C1=CC=C(NC(=O)NC2=CC=C(F)C=C2)C=C1",1.433,3,3,3]
["S2874","Camostat Mesilate","e9","L4000-05","in 10mM DMSO","COVID-19,Sodium Channel","Transmembrane Transporters","Camostat (FOY-305, FOY-S980) is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.",494.52,"59721-29-8",{"v":99,"d":"99.00"},200.19,{"v":10,"d":"10.00"},20.22,"http://selleckchem.com/products/camostat-mesilate-foy-305.html","C20H22N4O5.CH4O3S","Mesilate","FOY-305, FOY-S980","CN(C)C(=O)COC(=O)CC1=CC=C(OC(=O)C2=CC=C(NC(N)=N)C=C2)C=C1.C[S](O)(=O)=O",0.969,5,2,10]
["S2875","Prucalopride","f9","L4000-05","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Prucalopride (R-93877) is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively, exhibits >290-fold selectivity against other 5-HT receptor subtypes.",367.87,"179474-81-8",{"v":60,"d":"60.00"},{"v":163.1,"d":"163.10"},"<1","N/A","http://selleckchem.com/products/prucalopride.html","C18H26ClN3O3","Free Base","R-93877","COCCCN1CCC(CC1)NC(=O)C2=CC(=C(N)C3=C2OCC3)Cl",1.056,3,2,6]
["S2876","(+)-Dizocilpine (MK 801) Maleate","g9","L4000-05","in 10mM DMSO","NMDAR","Neuronal Signaling","(+)-Dizocilpine (MK 801) Maleate is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.",337.37,"77086-22-7",{"v":68,"d":"68.00"},201.56,"<1","N/A","http://selleckchem.com/products/mk-801-maleate.html","C16H15N.C4H4O4","maleate","N/A","CC12NC(CC3=C1C=CC=C3)C4=C2C=CC=C4.OC(=O)\\C=C/C(O)=O",0.376,2,1,2]
["S2891","GW441756","h9","L4000-05","in 10mM DMSO","Apoptosis related,Caspase,Trk receptor","Protein Tyrosine Kinase","GW441756 is a potent, selective inhibitor of TrkA with IC50 of 2 nM, with very little activity to c-Raf1 and CDK2. GW441756 produces a relevant increase of caspase-3 that leads to apoptosis.",{"v":275.3,"d":"275.30"},"504433-23-2",{"v":25,"d":"25.00"},90.81,"<1","N/A","http://selleckchem.com/products/gw-441756.html","C17H13N3O","free base","N/A","C[N]1C=C(C=C2C(=O)NC3=CC=CN=C23)C4=C1C=CC=C4",2.508,2,1,1]
["S2892","VU 0361737","a10","L4000-05","in 10mM DMSO","GluR","Neuronal Signaling","VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively, displays weak activity at mGlu5 and mGlu8 receptors, is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS.",262.69,"1161205-04-4",{"v":53,"d":"53.00"},201.76,"<1","N/A","http://selleckchem.com/products/vu-0361737.html","C13H11ClN2O2","free base","N/A","COC1=CC(=CC=C1Cl)NC(=O)C2=NC=CC=C2",{"v":2.54,"d":"2.540"},3,1,3]
["S2894","SB742457","b10","L4000-05","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","SB742457 (GSK 742457) is a highly selective 5-HT6 receptor antagonist with pKi of 9.63, exhibits >100-fold selectivity over other receptors. Phase 2.",353.44,"607742-69-8",{"v":78,"d":"78.00"},220.69,"<1","N/A","http://selleckchem.com/products/sb-742457.html","C19H19N3O2S","free base","GSK 742457","O=[S](=O)(C1=CC=CC=C1)C2=CC3=C(N=C2)C(=CC=C3)N4CCNCC4",2.702,3,1,3]
["S2903","Lumiracoxib","c10","L4000-05","in 10mM DMSO","COX","Neuronal Signaling","Lumiracoxib (COX-189) is a novel, selective COX-2 inhibitor with Ki of  0.06 μM. It also inhibits COX1 with Ki of 3 μM.",293.72,"220991-20-8",{"v":59,"d":"59.00"},200.87,"<1","N/A","http://selleckchem.com/products/lumiracoxib-cox-189.html","C15H13ClFNO2","free base","COX-189","CC1=CC=C(NC2=C(Cl)C=CC=C2F)C(=C1)CC(O)=O",{"v":4.4,"d":"4.400"},1,1,4]
["S2905","JNJ-7777120","d10","L4000-05","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist with Ki of 4.5 nM, exhibits >1000-fold selectivity over the other histamin receptors.",277.75,"459168-41-3",{"v":56,"d":"56.00"},201.62,"<1","N/A","http://selleckchem.com/products/jnj-7777120.html","C14H16ClN3O","free base","N/A","CN1CCN(CC1)C(=O)C2=CC3=CC(=CC=C3[NH]2)Cl",{"v":2.45,"d":"2.450"},1,1,1]
["S2910","Tempol","e10","L4000-05","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Tempol (4-Hydroxy-TEMPO) is a superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects. Phase 2.",172.24,"2226-96-2",{"v":34,"d":"34.00"},{"v":197.4,"d":"197.40"},{"v":34,"d":"34.00"},{"v":197.4,"d":"197.40"},"http://selleckchem.com/products/tempol-4-hydroxy-tempo.html","C9H18NO2","free base","4-Hydroxy-TEMPO","CC1(C)CC(O)CC(C)(C)N1[O]",0.413,0,1,0]
["S2918","HC-030031","f10","L4000-05","in 10mM DMSO","TRP Channel","Transmembrane Transporters","HC-030031 (TOSLAB 829227) is a selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx with IC50 of 6.2 μM and 5.3 μM respectively.",355.39,"349085-38-7",{"v":32,"d":"32.00"},90.04,"<1","N/A","http://selleckchem.com/products/hc-030031.html","C18H21N5O3","free base","TOSLAB 829227","CC(C)C1=CC=C(NC(=O)C[N]2C=NC3=C2C(=O)N(C)C(=O)N3C)C=C1",{"v":1.73,"d":"1.730"},4,1,4]
["S2929","Pifithrin-α (PFTα) HBr","g10","L4000-05","in 10mM DMSO","AhR,Autophagy,p53","Apoptosis","Pifithrin-α is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-responsive genes. Pifithrin-α is also a potent agonist of the aryl hydrocarbon receptor (AhR).",{"v":367.3,"d":"367.30"},"63208-82-2",{"v":67,"d":"67.00"},182.41,"<1","N/A","http://selleckchem.com/products/pifithrin-alpha.html","C16H18N2OS.HBr","HBr","Pifithrin-α hydrobromide","Br.CC1=CC=C(C=C1)C(=O)CN2C(=N)SC3=C2CCCC3",3.993,1,0,3]
["S3003","Prostaglandin E2 (PGE2)","h10","L4000-05","in 10mM DMSO","PGES,Prostaglandin Receptor","Endocrinology & Hormones","Prostaglandin E2 (PGE2, Dinoprostone,Prepidil) plays important effects in labour (softens cervix and causes uterine contraction) and also stimulates osteoblasts to release factors that stimulate bone resorption by osteoclasts.",352.47,"363-24-6",{"v":70,"d":"70.00"},{"v":198.6,"d":"198.60"},{"v":40,"d":"40.00"},113.49,"http://selleckchem.com/products/prostaglandin-e2-cervidil.html","C20H32O5","free base","Dinoprostone,Prepidil","CCCCCC(O)/C=C/C1C(O)CC(=O)C1C\\C=C/CCCC(O)=O",3.199,2,2,12]
["S3005","Paroxetine HCl","a11","L4000-05","in 10mM DMSO","Serotonin Transporter","Neuronal Signaling","Paroxetine HCl (BRL-29060A, FG-7051) is an antidepressant drug of the SSRI type.",365.83,"78246-49-8",{"v":73,"d":"73.00"},199.55,{"v":1,"d":"1.00"},2.73,"http://selleckchem.com/products/paroxetine-hcl.html","C19H20FNO3.HCl","Hydrochloride","BRL-29060A, FG-7051","Cl.FC1=CC=C(C=C1)C2CCNCC2COC3=CC4=C(OCO4)C=C3",3.611,3,1,4]
["S3008","Zaltoprofen","b11","L4000-05","in 10mM DMSO","COX","Neuronal Signaling","Zaltoprofen(CN100,Soleton) is an inhibitor of COX-1 and COX-2 for treatment of arthritis.",298.36,"74711-43-6",{"v":60,"d":"60.00"},{"v":201.1,"d":"201.10"},"<1","N/A","http://selleckchem.com/products/zaltoprofen.html","C17H14O3S","free base","CN100,Soleton","CC(C(O)=O)C1=CC2=C(SC3=CC=CC=C3C(=O)C2)C=C1",3.684,2,0,2]
["S3017","Aspirin (NSC 27223)","c11","L4000-05","in 10mM DMSO","Autophagy,COX,Mitophagy","Metabolism","Aspirin (NSC 27223, Acetylsalicylic acid, ASA) is a salicylate, and irreversible COX1 and COX2 inhibitor, used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. Aspirin induces autophagy and stimulates mitophagy.",180.16,"50-78-2",{"v":36,"d":"36.00"},199.82,"<1","N/A","http://selleckchem.com/products/aspirin-acetylsalicylic-acid.html","C9H8O4","free base","Acetylsalicylic acid, ASA","CC(=O)OC1=C(C=CC=C1)C(O)=O",1.227,3,0,3]
["S3018","Niflumic acid","d11","L4000-05","in 10mM DMSO","COX,GABA Receptor","Neuronal Signaling","Niflumic acid(Nifluril) is an inhibitor of cyclooxygenase-2 used for joint and muscular pain.",282.22,"4394-00-7",{"v":56,"d":"56.00"},198.43,"<1","N/A","http://selleckchem.com/products/niflumic-acid.html","C13H9F3N2O2","free base","Nifluril","OC(=O)C1=CC=CN=C1NC2=CC=CC(=C2)C(F)(F)F",{"v":3.34,"d":"3.340"},2,1,4]
["S3021","Rimonabant (SR141716)","e11","L4000-05","in 10mM DMSO","Acyltransferase,Bacterial,Cannabinoid Receptor,MmpL3,Transferase","GPCR & G Protein","Rimonabant (SR141716) is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Rimonabant is also a dual inhibitor of acyl CoA:cholesterol acyltransferases(ACAT) 1 and 2 and inhibits mycobacterial MmpL3.",463.79,"168273-06-1",{"v":25,"d":"25.00"},{"v":53.9,"d":"53.90"},"<1","N/A","http://selleckchem.com/products/rimonabant-sr141716.html","C22H21Cl3N4O","free base","SR141716","CC1=C([N](N=C1C(=O)NN2CCCCC2)C3=CC=C(Cl)C=C3Cl)C4=CC=C(Cl)C=C4",6.613,2,1,4]
["S3023","Bufexamac","f11","L4000-05","in 10mM DMSO","COX,IFN","Neuronal Signaling","Bufexamac(Bufexamic acid) is a COX inhibitor for IFN-α release with EC50 of 8.9 μM.",223.27,"2438-72-4",{"v":45,"d":"45.00"},201.55,"<1","N/A","http://selleckchem.com/products/bufexamac.html","C12H17NO3","free base","Bufexamic acid","CCCCOC1=CC=C(CC(=O)NO)C=C1",2.191,2,1,6]
["S3024","Lamotrigine","g11","L4000-05","in 10mM DMSO","5-HT Receptor,Sodium Channel","Transmembrane Transporters","Lamotrigine (BW-430C,LTG) is a novel anticonvulsant drug for inhibition of 5-HT with IC50 of 240 μM and 474 μM in human platelets and rat brain synaptosomes, and also is a sodium channel blocker.",256.09,"84057-84-1",{"v":10,"d":"10.00"},39.05,"<1","N/A","http://selleckchem.com/products/lamotrigine.html","C9H7Cl2N5","free base","BW-430C,LTG","NC1=NC(=C(N=N1)C2=CC=CC(=C2Cl)Cl)N",2.426,3,2,1]
["S3025","PMSF","h11","L4000-05","in 10mM DMSO","Cysteine Protease,Serine Protease","Proteases","PMSF (Phenylmethylsulfonyl Fluoride, Benzylsulfonyl fluoride) is an irreversible serine/cysteine protease inhibitor.",174.19,"329-98-6",{"v":35,"d":"35.00"},200.93,"<1","N/A","http://selleckchem.com/products/pmsf-phenylmethylsulfonyl-fluoride.html","C7H7FO2S","free base","Phenylmethylsulfonyl Fluoride, Benzylsulfonyl fluoride","F[S](=O)(=O)CC1=CC=CC=C1",1.459,2,0,2]
["S3037","Bepotastine Besilate","a2","L4000-06","in 10mM DMSO","COVID-19,Histamine Receptor","Neuronal Signaling","Bepotastine Besilate (TAU 284) is a non-sedating, selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7.",547.06,"190786-44-8",{"v":109,"d":"109.00"},199.25,"<1","N/A","http://selleckchem.com/products/bepotastine-besilate.html","C21H25ClN2O3.C6H6O3S","Besilate salt","TAU 284","OC(=O)CCCN1CCC(CC1)OC(C2=CC=C(Cl)C=C2)C3=NC=CC=C3.O[S](=O)(=O)C4=CC=CC=C4",1.371,3,0,9]
["S3038","Fosaprepitant dimeglumine salt","b2","L4000-06","in 10mM DMSO","Neurokinin Receptor","Neuronal Signaling","Fosaprepitant dimeglumine salt (MK-0517) is a water-soluble phosphoryl prodrug for Aprepitant which is a NK1 antagonist.",1004.83,"265121-04-8",{"v":201,"d":"201.00"},200.03,{"v":135,"d":"135.00"},134.35,"http://selleckchem.com/products/fosaprepitant.html","C23H22F7N4O6P.2C7H17NO5","dimeglumine salt","MK-0517","CNCC(O)C(O)C(O)C(O)CO.CNCC(O)C(O)C(O)C(O)CO.CC(OC1OCCN(CC2=NN(C(=O)N2)[P](O)(O)=O)C1C3=CC=C(F)C=C3)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F",-1.235,4,13,21]
["S3043","Rofecoxib","c2","L4000-06","in 10mM DMSO","COX","Neuronal Signaling","Rofecoxib (MK-0966) is a COX-2 inhibitor with IC50 of 18 nM.",314.36,"162011-90-7",{"v":63,"d":"63.00"},200.41,"<1","N/A","http://selleckchem.com/products/rofecoxib-vioxx.html","C17H14O4S","free base","MK-0966","C[S](=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3",2.871,4,0,3]
["S3045","Cinepazide maleate","d2","L4000-06","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Cinepazide maleate is a maleate salt form of cinepazide which is a vasodilator.",533.57,"26328-04-1",{"v":107,"d":"107.00"},200.54,{"v":107,"d":"107.00"},200.54,"http://selleckchem.com/products/cinepazide-maleate.html","C22H31N3O5.C4H4O4","Maleate","N/A","COC1=C(OC)C(=CC(=C1)/C=C/C(=O)N2CCN(CC2)CC(=O)N3CCCC3)OC.OC(=O)\\C=C/C(O)=O",{"v":-1.65,"d":"-1.650"},7,0,9]
["S3046","Azilsartan","e2","L4000-06","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Azilsartan (TAK-536) is an angiotensin II type 1 (AT1) receptor antagonist with IC50 of 2.6 nM.",456.45,"147403-03-0",{"v":91,"d":"91.00"},199.36,"<1","N/A","http://selleckchem.com/products/azilsartan-tak-536.html","C25H20N4O5","free base","TAK-536","CCOC1=NC2=CC=CC(=C2[N]1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)ON5)C(O)=O",4.662,6,1,7]
["S3047","Otilonium Bromide","f2","L4000-06","in 10mM DMSO","AChR","Neuronal Signaling","Otilonium bromide is an antimuscarinic.",563.57,"26095-59-0",{"v":113,"d":"113.00"},200.51,{"v":113,"d":"113.00"},200.51,"http://selleckchem.com/products/otilonium-bromide.html","C29H43BrN2O4","quaternary-N bromide salt","N/A","[Br-].CCCCCCCCOC1=CC=CC=C1C(=O)NC2=CC=C(C=C2)C(=O)OCC[N+](C)(CC)CC",{"v":2.67,"d":"2.670"},4,1,17]
["S3052","Rupatadine Fumarate","g2","L4000-06","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Rupatadine is an inhibitor of PAFR and histamine (H1) receptor with Ki of 550 nM and 102 nM, respectively.",532.03,"182349-12-8",{"v":9,"d":"9.00"},16.92,"<1","N/A","http://selleckchem.com/products/rupatadine-fumarate.html","C26H26ClN3.C4H4O4","Fumarate","N/A","CC1=CN=CC(=C1)CN2CCC(CC2)=C3C4=CC=C(Cl)C=C4CCC5=CC=CN=C35.OC(=O)\\C=C\\C(O)=O",2.672,4,0,4]
["S3053","Azelnidipine","h2","L4000-06","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Azelnidipine (UR-12592) is a dihydropyridine calcium channel blocker.",582.65,"123524-52-7",{"v":117,"d":"117.00"},200.81,"<1","N/A","http://selleckchem.com/products/azelnidipine.html","C33H34N4O6","free base","UR-12592","CC(C)OC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OC3CN(C3)C(C4=CC=CC=C4)C5=CC=CC=C5)N",4.941,4,2,11]
["S3054","Alverine Citrate","a3","L4000-06","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Alverine citrate (NSC 35459) is a drug used for functional gastrointestinal disorders. Alverine citrate is a 5-HT1A receptor antagonist, with an IC50 of 101 nM.",473.56,"5560-59-8",{"v":95,"d":"95.00"},200.61,"<1","N/A","http://selleckchem.com/products/alverine-citrate.html","C20H27N.C6H8O7","Citrate","NSC 35459","CCN(CCCC1=CC=CC=C1)CCCC2=CC=CC=C2.OC(=O)CC(O)(CC(O)=O)C(O)=O",1.037,3,0,14]
["S3057","Azilsartan Medoxomil","b3","L4000-06","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Azilsartan Medoxomil (TAK-491) is a potent angiotensin II type 1 (AT1) receptor antagonist, inhibits the RAAS, with an IC50 of 2.6 nM, exhibits >10,000-fold selectivity over AT2.",568.53,"863031-21-4",{"v":114,"d":"114.00"},200.52,"<1","N/A","http://selleckchem.com/products/azilsartan-medoxomil-tak-491.html","C30H24N4O8","free base","TAK-491","CCOC1=NC2=CC=CC(=C2[N]1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)ON5)C(=O)OCC6=C(C)OC(=O)O6",{"v":5.27,"d":"5.270"},10,1,10]
["S3060","Medetomidine HCl","c3","L4000-06","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Medetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.",236.74,"86347-15-1",{"v":12,"d":"12.00"},50.69,{"v":47,"d":"47.00"},198.53,"http://selleckchem.com/products/medetomidine-hcl.html","C13H16N2.HCl","HCl","N/A","Cl.CC(C1=C[NH]C=N1)C2=C(C)C(=CC=C2)C",3.515,1,1,2]
["S3061","Epinephrine HCl","d3","L4000-06","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Epinephrine HCl (Adrenaline) is a hormone and a neurotransmitter.",219.67,"55-31-2",{"v":44,"d":"44.00"},{"v":200.3,"d":"200.30"},{"v":44,"d":"44.00"},{"v":200.3,"d":"200.30"},"http://selleckchem.com/products/epinephrine-hcl-adrenaline.html","C9H13NO3.HCl","HCl","Adrenaline","Cl.CNCC(O)C1=CC=C(O)C(=C1)O",0.754,0,4,3]
["S3063","Diclofenac Diethylamine","e3","L4000-06","in 10mM DMSO","COX","Neuronal Signaling","Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions. Diclofenac exerts its action via inhibition of prostaglandin synthesis by inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) with relative equipotency.",369.29,"78213-16-8",{"v":74,"d":"74.00"},200.38,"<1","N/A","http://selleckchem.com/products/diclofenac-diethylamine.html","C14H11Cl2NO2.C4H11N","Diethylamine","N/A","CCNCC.OC(=O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl",{"v":2.15,"d":"2.150"},1,2,6]
["S3066","Naloxone HCl","f3","L4000-06","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","Naloxone HCl is an opioid inverse agonist drug used to counter the effects of opiate overdose.",363.84,"357-08-4",{"v":72,"d":"72.00"},197.89,{"v":72,"d":"72.00"},197.89,"http://selleckchem.com/products/naloxone-hcl.html","C19H21NO4.HCl","HCl","N/A","Cl.OC1=C2OC3C(=O)CCC4(O)C5CC(=C2C34CCN5CC=C)C=C1",1.835,2,1,2]
["S3070","Piracetam","g3","L4000-06","in 10mM DMSO","GluR","Neuronal Signaling","Piracetam (UCB 6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders.",142.16,"7491-74-9",{"v":72,"d":"72.00"},506.47,{"v":72,"d":"72.00"},506.47,"http://selleckchem.com/products/piracetam.html","C6H10N2O2","free base","UCB 6215","NC(=O)CN1CCCC1=O",-1.312,2,1,2]
["S3071","Vanillin","h3","L4000-06","in 10mM DMSO","Others","Others","Vanillin (FEMA 3107), 4-hydroxy-3-methoxybenzaldehyde is a food additive.",152.15,"121-33-5",{"v":30,"d":"30.00"},197.17,"<1","N/A","http://selleckchem.com/products/vanillin.html","C8H8O3","free base","FEMA 3107","COC1=CC(=CC=C1O)C=O",{"v":1.33,"d":"1.330"},2,1,2]
["S3078","Beclomethasone dipropionate","a4","L4000-06","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Beclomethasone dipropionate(Beclovent,Beconase,Vancenase)  is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.",521.04,"5534-09-8",{"v":104,"d":"104.00"},{"v":199.6,"d":"199.60"},"<1","N/A","http://selleckchem.com/products/beclomethasone-dipropionate.html","C28H37ClO7","free base","Beclometasone dipropionate,Beclovent,Beconase,Vancenase","CCC(=O)OCC(=O)C1(OC(=O)CC)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(Cl)C(O)CC12C",4.064,6,1,8]
["S3083","Indacaterol Maleate","b4","L4000-06","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Indacaterol (QAB149) is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor.",508.56,"753498-25-8",{"v":102,"d":"102.00"},200.57,"<1","N/A","http://selleckchem.com/products/indacaterol-maleate.html","C24H28N2O3.C4H4O4","Maleate","QAB149","CCC1=CC2=C(CC(C2)NCC(O)C3=CC=C(O)C4=C3C=CC(=O)N4)C=C1CC.OC(=O)\\C=C/C(O)=O",1.264,3,4,8]
["S3100","2-Thiouracil","c4","L4000-06","in 10mM DMSO","Hydroxylase","Neuronal Signaling","2-Thiouracil(Deracil,Thiouracil) is a thiolated uracil derivative that is a known antihyperthyroid agent.",128.15,"141-90-2",{"v":26,"d":"26.00"},202.89,"<1","N/A","http://selleckchem.com/products/2-thiouracil.html","C4H4N2OS","free base","Deracil,Thiouracil","O=C1NC(=S)NC=C1",0.081,1,2,0]
["S3117","Oxybutynin hydrochloride","d4","L4000-06","in 10mM DMSO","AChR","Neuronal Signaling","Oxybutynin(MJ4309-1) is an anticholinergic medication used to relieve urinary and bladder difficulties.",393.95,"1508-65-2",{"v":79,"d":"79.00"},200.53,{"v":4,"d":"4.00"},10.15,"https://www.selleckchem.com/products/oxybutynin-hydrochloride.html","C22H31NO3.HCl","hydrochloride","MJ4309-1","Cl.CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)C2=CC=CC=C2",5.028,2,0,10]
["S3120","Doxepin HCl","e4","L4000-06","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Doxepin is a tricyclic antidepressant formulated as a mixture of E-(trans) and Z-(cis) stereoisomers. It inhibits CYP2D6 activity in vivo.",315.84,"1229-29-4",{"v":63,"d":"63.00"},199.47,{"v":63,"d":"63.00"},199.47,"http://selleckchem.com/products/doxepin-hydrochloride-sinequan.html","C19H21NO.HCl","hydrochloride","N/A","Cl.CN(C)CC\\C=C1/C2=CC=CC=C2COC3=C1C=CC=C3",{"v":4.29,"d":"4.290"},1,0,3]
["S3140","Milnacipran HCl","f4","L4000-06","in 10mM DMSO","Serotonin Transporter","Neuronal Signaling","Milnacipran inhibits both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively.",282.81,"101152-94-7",{"v":57,"d":"57.00"},201.55,{"v":57,"d":"57.00"},201.55,"http://selleckchem.com/products/milnacipran-hydrochloride.html","C15H22N2O.HCl","HCl","N/A","Cl.CCN(CC)C(=O)C1(CC1CN)C2=CC=CC=C2",{"v":1.67,"d":"1.670"},1,1,5]
["S3144","Darifenacin HBr","g4","L4000-06","in 10mM DMSO","AChR","Neuronal Signaling","Darifenacin HBr (UK-88525) is a selective M3 muscarinic receptor antagonist with pKi of 8.9.",507.46,"133099-07-7",{"v":100,"d":"100.00"},197.06,"<1","N/A","http://selleckchem.com/products/darifenacin-hydrobromide.html","C28H30N2O2.HBr","HBr","UK-88525","Br.NC(=O)C(C1CCN(CCC2=CC=C3OCCC3=C2)C1)(C4=CC=CC=C4)C5=CC=CC=C5",5.048,2,1,7]
["S3147","Entacapone","h4","L4000-06","in 10mM DMSO","COMT,Histone Methyltransferase","Epigenetics","Entacapone (OR-611) inhibits catechol-O-methyltransferase(COMT) with IC50 of 151 nM. Entacapone can be used for the research of Parkinson's disease. Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders.",305.29,"130929-57-6",{"v":61,"d":"61.00"},199.81,"<1","N/A","http://selleckchem.com/products/entacapone.html","C14H15N3O5","free base","OR-611","CCN(CC)C(=O)\\C(=C\\C1=CC(=C(O)C(=C1)O)[N+]([O-])=O)C#N",1.658,1,2,5]
["S3150","Articaine HCl","a5","L4000-06","in 10mM DMSO","NF-κB","Immunology & Inflammation","Articaine (Ultracaine) is a dental local anesthetic which contains an additional ester group that is metabolized by estearases in blood and tissue.",320.84,"23964-57-0",{"v":64,"d":"64.00"},199.48,{"v":64,"d":"64.00"},199.48,"http://selleckchem.com/products/articaine-hydrochloride.html","C13H20N2O3S.HCl","Hydrochloride","Ultracaine","Cl.CCCNC(C)C(=O)NC1=C(SC=C1C)C(=O)OC",2.454,3,2,7]
["S3153","Levalbuterol tartrate","b5","L4000-06","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Levalbuterol HCl(Levosalbutamol tartrate) is a relatively selective beta2-adrenergic receptor agonist used for the treatment of asthma.",628.71,"661464-94-4",{"v":100,"d":"100.00"},159.06,{"v":100,"d":"100.00"},159.06,"http://www.selleck.cn/products/levalbuterol-hydrochloride.html","C30H48N2O12","tartrate","Levosalbutamol tartrate","CC(C)(C)NCC(O)C1=CC=C(O)C(=C1)CO.CC(C)(C)NCC(O)C2=CC=C(O)C(=C2)CO.OC(C(O)C(O)=O)C(O)=O",{"v":-5.19,"d":"-5.190"},2,10,13]
["S3155","Mepivacaine HCl","c5","L4000-06","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Mepivacaine is a tertiary amine used as a local anesthetic.",282.81,"1722-62-9",{"v":3,"d":"3.00"},10.61,{"v":57,"d":"57.00"},201.55,"http://selleckchem.com/products/mepivacaine-hydrochloride.html","C15H22N2O.HCl","HCl","N/A","Cl.CN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",3.363,1,1,2]
["S3163","Benztropine mesylate","d5","L4000-06","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Benztropine(Cogentin mesylate, Benztropine methanesulfonate) is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM.",403.53,"132-17-2",{"v":50,"d":"50.00"},123.91,{"v":81,"d":"81.00"},200.73,"http://selleckchem.com/products/benztropine-mesylate.html","C21H25NO.CH4SO3","Mesylate","Cogentin mesylate, Benztropine methanesulfonate","CN1C2CCC1CC(C2)OC(C3=CC=CC=C3)C4=CC=CC=C4.C[S](O)(=O)=O",3.461,1,0,4]
["S3173","Antipyrine","e5","L4000-06","in 10mM DMSO","COX","Neuronal Signaling","Antipyrine (Phenazone,Phenazon) is an analgesic and antipyretic agent; selective COX-3 inhibitor.",188.23,"60-80-0",{"v":38,"d":"38.00"},201.88,{"v":38,"d":"38.00"},201.88,"http://selleckchem.com/products/antipyrine.html","C11H12N2O","free base","Phenazone,Phenazon","CN1N(C(=O)C=C1C)C2=CC=CC=C2",1.218,1,0,1]
["S3175","Atomoxetine HCl","f5","L4000-06","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Atomoxetine (LY 139603) is a selective norepinephrine (NE) transporter inhibitor with Ki of 5 nM, with 15- and 290-fold lower affinity for human 5-HT and DA transporters.",291.82,"82248-59-7",{"v":58,"d":"58.00"},198.75,{"v":2,"d":"2.00"},6.85,"http://selleckchem.com/products/atomoxetine-hydrochloride.html","C17H21NO.HCl","HCl","LY 139603 HCl","Cl.CNCCC(OC1=CC=CC=C1C)C2=CC=CC=C2",3.959,1,1,6]
["S3176","Betahistine 2HCl","g5","L4000-06","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Betahistine (PT-9) is a histamine H3 receptor inhibitor with IC50 of 1.9 μM.",209.12,"5579-84-0",{"v":38,"d":"38.00"},181.71,{"v":38,"d":"38.00"},181.71,"http://selleckchem.com/products/betahistine-dihydrochloride.html","C8H12N2.2HCl","2HCl","PT-9","Cl.Cl.CNCCC1=NC=CC=C1",1.444,1,1,3]
["S3178","Brinzolamide","h5","L4000-06","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Brinzolamide (AL-4862) is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM.",383.51,"138890-62-7",{"v":77,"d":"77.00"},200.78,"<1","N/A","http://selleckchem.com/products/brinzolamide.html","C12H21N3O5S3","free base","AL-4862","CCNC1CN(CCCOC)[S](=O)(=O)C2=C1C=C(S2)[S](N)(=O)=O",-0.772,5,2,7]
["S3180","Eletriptan HBr","a6","L4000-06","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Eletriptan (UK-116044) is a selective 5-HT1B and 5-HT1D receptor agonist with Ki of 0.92 nM and 3.14 nM, respectively.",463.43,"177834-92-3",{"v":93,"d":"93.00"},200.68,"<1","N/A","http://selleckchem.com/products/eletriptan-hydrobromide.html","C22H26N2O2S.HBr","HBr","UK-116044","Br.CN1CCCC1CC2=C[NH]C3=C2C=C(CC[S](=O)(=O)C4=CC=CC=C4)C=C3",4.929,2,1,6]
["S3183","Amitriptyline HCl","b6","L4000-06","in 10mM DMSO","5-HT Receptor,Histamine Receptor,Serotonin Transporter","Neuronal Signaling","Amitriptyline HCl is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline HCl also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. Amitriptyline is a tricyclic antidepressant (TCA).",313.86,"549-18-8",{"v":63,"d":"63.00"},200.73,{"v":15,"d":"15.00"},47.79,"http://selleckchem.com/products/amitriptyline-hydrochloride.html","C20H23N.HCl","HCl","N/A","Cl.CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C13",5.154,0,0,3]
["S3185","Adrenalone HCl","c6","L4000-06","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic, mainly acts on alpha-1 adrenergic receptors.",217.65,"62-13-5",{"v":44,"d":"44.00"},202.16,{"v":44,"d":"44.00"},202.16,"http://selleckchem.com/products/adrenalone-hcl.html","C9H11NO3.HCl","HCl","N/A","Cl.CNCC(=O)C1=CC(=C(O)C=C1)O",0.938,1,3,3]
["S3186","Azatadine dimaleate","d6","L4000-06","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Azatadine (SCH10649,Azatadine Maleate) is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively.",522.55,"3978-86-7",{"v":105,"d":"105.00"},200.94,{"v":105,"d":"105.00"},200.94,"http://selleckchem.com/products/azatadine-dimaleate.html","C20H22N2.2C4H4O4","Dimaleate","SCH10649,Azatadine Maleate","CN1CCC(CC1)=C2C3=CC=CC=C3CCC4=CC=CN=C24.OC(=O)\\C=C/C(O)=O.OC(=O)\\C=C/C(O)=O",1.128,5,0,4]
["S3189","Ropinirole HCl","e6","L4000-06","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Ropinirole (SKF-101468A) a selective dopamine D2 receptors agonist with Ki of 29 nM.",296.84,"91374-20-8",{"v":10,"d":"10.00"},33.69,{"v":60,"d":"60.00"},202.13,"http://selleckchem.com/products/ropinirole-hydrochloride.html","C16H24N2O.HCl","HCl","SKF-101468A","Cl.CCCN(CCC)CCC1=CC=CC2=C1CC(=O)N2",3.341,1,1,7]
["S3196","Azacyclonol","f6","L4000-06","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Azacyclonol (MER 17, MDL 4829), also known as γ-pipradol, is a drug used to diminish hallucinations in psychotic individuals.",267.37,"115-46-8",{"v":53,"d":"53.00"},198.23,{"v":2,"d":"2.00"},7.48,"http://selleckchem.com/products/azacyclonol.html","C18H21NO","free base","MER 17, MDL 4829","OC(C1CCNCC1)(C2=CC=CC=C2)C3=CC=CC=C3",2.846,0,1,3]
["S3199","Reboxetine mesylate","g6","L4000-06","in 10mM DMSO","Others","Endocrinology & Hormones","Reboxetine (PNU 155950E) is a norepinephrine reuptake inhibitor with Ki of 8.2 nM.",{"v":409.5,"d":"409.50"},"98769-84-7",{"v":82,"d":"82.00"},200.24,{"v":82,"d":"82.00"},200.24,"http://selleckchem.com/products/reboxetine-mesylate.html","C19H23NO3.CH4O3S","Mesylate","PNU 155950E, FCE20124 mesylate","CCOC1=C(OC(C2CNCCO2)C3=CC=CC=C3)C=CC=C1.C[S](O)(=O)=O",2.663,3,1,6]
["S3200","Triflusal","h6","L4000-06","in 10mM DMSO","COX","Immunology & Inflammation","Triflusal (UR1501) irreversibly inhibits the production of thromboxane-B2 in platelets by acetylating cycloxygenase-1.",248.16,"322-79-2",{"v":50,"d":"50.00"},201.48,"<1","N/A","http://selleckchem.com/products/triflusal.html","C10H7F3O4","free base","UR1501","CC(=O)OC1=CC(=CC=C1C(O)=O)C(F)(F)F",2.169,3,0,4]
["S3201","Trifluoperazine 2HCl","a7","L4000-06","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Trifluoperazine (NSC-17474, RP-7623, SKF-5019) 2HCl is a dopamine D2 receptor inhibitor with IC50 of 1.1 nM. Trifluoperazine also inhibits calmodulin (CaM).",480.42,"440-17-5",{"v":88,"d":"88.00"},183.17,{"v":96,"d":"96.00"},199.83,"http://selleckchem.com/products/trifluoperazine-dihydrochloride.html","C21H24F3N3S.2HCl","2HCl","SKF5019","Cl.Cl.CN1CCN(CCCN2C3=C(SC4=CC=C(C=C24)C(F)(F)F)C=CC=C3)CC1",5.739,0,0,5]
["S3208","Fexofenadine HCl","b7","L4000-06","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Fexofenadine (MDL 16455A) inhibits histamine H1 receptor with IC50 of 246 nM.",538.12,"153439-40-8",{"v":107,"d":"107.00"},198.84,{"v":2,"d":"2.00"},3.72,"http://selleckchem.com/products/fexofenadine-hcl.html","C32H39NO4.HCl","HCl","MDL 16455A","Cl.CC(C)(C(O)=O)C1=CC=C(C=C1)C(O)CCCN2CCC(CC2)C(O)(C3=CC=CC=C3)C4=CC=CC=C4",2.989,1,1,10]
["S3212","Moclobemide (Ro 111163)","c7","L4000-06","in 10mM DMSO","MAO","Metabolism","Moclobemide is a MAO-A (5-HT) inhibitor with IC50 of 6.1 μM.",268.74,"71320-77-9",{"v":53,"d":"53.00"},197.22,"<1","N/A","http://selleckchem.com/products/moclobemide.html","C13H17ClN2O2","free base","N/A","ClC1=CC=C(C=C1)C(=O)NCCN2CCOCC2",1.528,2,1,4]
["S3600","Schisandrin B (Sch B)","d7","L4000-06","in 10mM DMSO","ATM/ATR,P-gp","PI3K/Akt/mTOR","Schisandrin B is the most abundant dibenzocyclooctadiene lignan present in the traditional Chinese medicinal herb Schisandra chinensis (Turcz.) Baill. It is a kind of ATR and P-gp inhibitor with high safety.",400.46,"61281-37-6",{"v":80,"d":"80.00"},199.77,"<1","N/A","http://selleckchem.com/products/schisandrin-b.html","C23H28O6","free base","N/A","COC1=CC2=C(C(=C1OC)OC)C3=C(CC(C)C(C)C2)C=C4OCOC4=C3OC",5.067,6,0,4]
["S3611","(+)-Fangchinoline","e7","L4000-06","in 10mM DMSO","Others","Others","Fangchinoline ((+)-Limacine, Tetrandrine B, Hanfangichin B) is a phytochemical that has been shown to elicit anti-cancer effects in prostate and breast cancer cell lines via inducing G1 cell cycle arrest. It has also been shown to possess neuroprotective activity.",608.72,"436-77-1",{"v":40,"d":"40.00"},65.71,"<1","N/A","http://selleckchem.com/products/s-s-fangchinoline.html","C37H40N2O6","free base","(+)-Limacine, Tetrandrine B, Hanfangichin B","COC1=C2OC3=CC=C(CC4N(C)CCC5=C4C=C(OC6=C7C(CC(=C2)C=C1)N(C)CCC7=CC(=C6O)OC)C(=C5)OC)C=C3",6.992,5,1,3]
["S3612","Rosmarinic acid","f7","L4000-06","in 10mM DMSO","Complement System,IκB/IKK","NF-κB","Rosmarinic acid (RA, Rosemary acid) is a naturally occurring hydroxylated compound. It has the ability to block complement fixation, inhibit lipoxygenase and cyclooxygenase activity and inhibit the expression of CCL11 and CCR3 by suppressing the IKK-β activity in NF-κB activation signaling.",360.31,"20283-92-5",{"v":72,"d":"72.00"},199.83,{"v":24,"d":"24.00"},66.61,"http://selleckchem.com/products/rosmarinic-acid.html","C18H16O8","free base","Rosemary acid","OC(=O)C(CC1=CC=C(O)C(=C1)O)OC(=O)\\C=C\\C2=CC=C(O)C(=C2)O",2.706,3,4,7]
["S3616","Asiaticoside","g7","L4000-06","in 10mM DMSO","ROS","Immunology & Inflammation","Asiaticoside (Ba 2742, BRN0078195, CCRIS8995, NSC166062, Emdecassol,Madecassol), the major active principle of Centella asiatica, prevents ultraviolet A-dependent photoaging by suppressing ultraviolet A-induced reactive oxygen species production. It also decreases DNA binding by MITF.",959.12,"16830-15-2",{"v":100,"d":"100.00"},104.26,"<1","N/A","http://selleckchem.com/products/asiaticoside.html","C48H78O19","free base","Ba 2742, BRN0078195, CCRIS8995, NSC166062, Emdecassol,Madecassol","CC1CCC2(CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(CO)C5CCC34C)C2C1C)C(=O)OC6OC(COC7OC(CO)C(OC8OC(C)C(O)C(O)C8O)C(O)C7O)C(O)C(O)C6O",-0.101,7,12,10]
["S3617","(20S)-Protopanaxatriol","h7","L4000-06","in 10mM DMSO","Estrogen/progestogen Receptor,Glucocorticoid Receptor","Endocrinology & Hormones","(20S)-Protopanaxatriol (g-PPT, 20(S)-APPT), a neuroprotective metabolite of ginsenoside, protopanaxatriol (g-PPT), is a functional ligand for both GR and ERbeta and could modulate endothelial cell functions through the glucocorticoid receptor (GR) and estrogen receptor (ER).",476.73,"34080-08-5",{"v":95,"d":"95.00"},199.27,"<1","N/A","http://selleckchem.com/products/20s-protopanaxatriol.html","C30H52O4","free base","g-PPT, 20(S)-APPT","CC(C)=CCCC(C)(O)C1CCC2(C)C1C(O)CC3C4(C)CCC(O)C(C)(C)C4C(O)CC23C",{"v":4.62,"d":"4.620"},0,3,4]
["S3622","Diammonium Glycyrrhizinate","a8","L4000-06","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Diammonium glycyrrhizinate (DG), a traditional Chinese medicine (TCM), is extracted and purified from liquorices (Radix glycyrrhizae). It is known for its anti-inflammatory effects, resistance to biologic oxidation and membranous protection. DG is able to reduce inflammatory injury via suppression of NF‑κB, TNF‑α and intercellular adhesion molecule 1.",856.99,"79165-06-3",{"v":100,"d":"100.00"},116.69,{"v":100,"d":"100.00"},116.69,"http://selleckchem.com/products/diammonium-glycyrrhizinate.html","C42H62O16.2H3N","ammonium salt","N/A","N.N.CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O)OC6OC(C(O)C(O)C6OC7OC(C(O)C(O)C7O)C(O)=O)C(O)=O",-4.247,8,5,7]
["S3624","Quinolinic acid","b8","L4000-06","in 10mM DMSO","NMDAR","Neuronal Signaling","Quinolinic Acid (pyridine-2,3-dicarboxylic acid, QUIN), a neuroactive metabolite of the kynurenine pathway, is an agonist of N-methyl-D-aspartate (NMDA) receptor.",167.12,"89-00-9",{"v":25,"d":"25.00"},149.59,{"v":3,"d":"3.00"},17.95,"http://selleckchem.com/products/quinolinic-acid.html","C7H5NO4","free base","pyridine-2,3-dicarboxylic acid, QUIN","OC(=O)C1=CC=CN=C1C(O)=O",0.367,3,0,2]
["S3625","Tyramine","c8","L4000-06","in 10mM DMSO","TAAR","GPCR & G Protein","Tyramine (4-hydroxyphenethylamine, para-tyramine, mydrial, uteramin) is a naturally occurring trace amine derived from the amino acid tyrosine and acts as a catecholamine releasing agent.",137.18,"51-67-2",{"v":27,"d":"27.00"},196.82,"<1","N/A","http://selleckchem.com/products/tyramine.html","C8H11NO","free base","4-hydroxyphenethylamine, para-tyramine, mydrial, uteramin","NCCC1=CC=C(O)C=C1",1.015,0,2,2]
["S3627","Tryptamine","d8","L4000-06","in 10mM DMSO","TAAR","GPCR & G Protein","Tryptamine is a monoamine alkaloid and may play a role as a neuromodulator or neurotransmitter. It is an agonist of hTAAR1. It acts as a non-selective serotonin receptor agonist and serotonin-norepinephrine-dopamine releasing agent (SNDRA).",160.22,"61-54-1",{"v":32,"d":"32.00"},199.73,"<1","N/A","http://selleckchem.com/products/tryptamine.html","C10H12N2","free base","N/A","NCCC1=C[NH]C2=CC=CC=C12",{"v":1.55,"d":"1.550"},0,2,2]
["S3629","Syringic acid","e8","L4000-06","in 10mM DMSO","Antioxidant","Angiogenesis","Syringic acid (NSC 2129, SYRA) is a potential antioxidant used in traditional Chinese medicine and is an emerging nutraceutical. It has potential anti-angiogenic, anti-glycating, anti-hyperglycaemic, neuroprotective, and memory-enhancing properties.",198.17,"530-57-4",{"v":39,"d":"39.00"},{"v":196.8,"d":"196.80"},{"v":1,"d":"1.00"},5.05,"http://selleckchem.com/products/syringic-acid.html","C9H10O5","free base","3,5-dimethyl ether Gallic Acid, 3,5-dimethoxy-4-hydroxy Benzoic Acid, NSC 2129, SYRA","COC1=CC(=CC(=C1O)OC)C(O)=O",1.184,3,1,3]
["S3634","6-Hydroxyflavone (6-HF)","f8","L4000-06","in 10mM DMSO","GABA Receptor","Transmembrane Transporters","6-Hydroxyflavone, a naturally occurring flavonoid, binds to GABAA receptors with moderate affinity and acts as a partial agonist of GABAA receptors.",238.24,"6665-83-4",{"v":47,"d":"47.00"},197.28,"<1","N/A","http://selleckchem.com/products/6-hydroxyflavone-6-hf.html","C15H10O3","free base","N/A","OC1=CC2=C(OC(=CC2=O)C3=CC=CC=C3)C=C1",2.894,2,1,1]
["S3639","Tacrine hydrochloride hydrate","g8","L4000-06","in 10mM DMSO","AChR,HNMT","Neuronal Signaling","Tacrine (Tetrahydroaminacrine, Tetrahydroaminoacridine) is a centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. It also acts as a histamine N-methyltransferase inhibitor.","198.26(free bases)","206658-92-6",{"v":50,"d":"50.00"},252.19,{"v":50,"d":"50.00"},252.19,"http://selleckchem.com/products/tacrine-hydrochloride-hydrate.html","C13H14N2.xHCl.xH2O","hydrochloride hydrate","Tacrine, Tetrahydroaminacrine, Tetrahydroaminoacridine","NC1=C2C=CC=CC2=NC3=C1CCCC3",4.258,1,1,0]
["S3640","Methoxyphenamine Hydrochloride","h8","L4000-06","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Methoxyphenamine Hydrochloride (2-methoxy-N-methylamphetamine, OMMA) is a β-adrenergic receptor agonist of the amphetamine class used as a bronchodilator.",215.72,"5588-10-3",{"v":43,"d":"43.00"},199.33,{"v":43,"d":"43.00"},199.33,"http://selleckchem.com/products/methoxyphenamine-hydrochloride.html","C11H17N.HCl","hydrochloride","2-methoxy-N-methylamphetamine Hydrochloride, OMMA Hydrochloride","Cl.CNC(C)CC1=CC=CC=C1OC",2.431,1,1,4]
["S3643","Amitraz","a9","L4000-06","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Amitraz (NSC 324552) is a triazapentadiene, an α2 adrenergic agonist and a member of the amidine chemical family. It is a non-systemic acaricide and insecticide.",293.41,"33089-61-1",{"v":58,"d":"58.00"},197.68,"<1","N/A","http://selleckchem.com/products/amitraz.html","C19H23N3","free base","NSC 324552","CN(C=NC1=CC=C(C)C=C1C)C=NC2=CC=C(C)C=C2C",4.825,2,0,4]
["S3647","Mafenide Acetate","b9","L4000-06","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Mafenide Acetate is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.",246.28,"13009-99-9",{"v":49,"d":"49.00"},198.96,{"v":49,"d":"49.00"},198.96,"http://selleckchem.com/products/mafenide-acetate.html","C7H10N2O2S.C2H4O2","acetate","N/A","CC(O)=O.NCC1=CC=C(C=C1)[S](N)(=O)=O",-3.043,3,2,2]
["S3653","Spermidine trihydrochloride","c9","L4000-06","in 10mM DMSO","Autophagy,NMDAR","Neuronal Signaling","Spermidine (4-Azaoctamethylenediamine), a natural polyamine produced from putrescine and decarboxylated S-adenosylmethionine (dcSAM) by spermidine synthase, is a novel autophagy inducer and negatively modulates N-methyl-d-aspartate (NMDA).",254.63,"334-50-9",{"v":30,"d":"30.00"},117.82,{"v":50,"d":"50.00"},196.36,"http://selleckchem.com/products/spermidine-trihydrochloride.html","C7H19N3.3HCl","trihydrochloride","4-Azaoctamethylenediamine trihydrochloride","Cl.Cl.Cl.NCCCCNCCCN",-0.024,0,3,7]
["S3654","Tauroursodeoxycholic Acid (TUDCA)","d9","L4000-06","in 10mM DMSO","Mitochondrial Metabolism","Neuronal Signaling","Tauroursodeoxycholic acid (TUDCA) is the taurine conjugate of ursodeoxycholic acid (UDCA) and acts as a mitochondrial stabilizer and anti-apoptotic agent in several models of neurodegenerative diseases, including AD, Parkinson's diseases (PD), and Huntington's diseases (HD).",{"v":499.7,"d":"499.70"},"14605-22-2",{"v":99,"d":"99.00"},198.12,{"v":30,"d":"30.00"},60.04,"http://selleckchem.com/products/tauroursodeoxycholic-acid.html","C26H45NO6S","free base","N/A","CC(CCC(=O)NCC[S](O)(=O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C",2.997,1,3,7]
["S3656","Piribedil","e9","L4000-06","in 10mM DMSO","Adrenergic Receptor,Dopamine Receptor","Neuronal Signaling","Piribedil (Trivastal, Trivastan) is a relatively selective dopamine (D2/D3) agonist with moderate antidepressant activity. It also has α2-adrenergic (α2A/α2C) antagonist properties.",298.34,"3605-01-4",{"v":59,"d":"59.00"},197.76,"<1","N/A","http://selleckchem.com/products/piribedil.html","C16H18N4O2","free base","Trivastal, Trivastan","C1OC2=CC=C(CN3CCN(CC3)C4=NC=CC=N4)C=C2O1",2.043,4,0,3]
["S3663","Afloqualone","f9","L4000-06","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Afloqualone (AFQ, HQ-495) is a quinazolinone family GABAergic drug with muscle-relaxant and sedative effects, showing the agonist activity at the β subtype of the GABAa receptor.",{"v":283.3,"d":"283.30"},"56287-74-2",{"v":56,"d":"56.00"},197.67,"<1","N/A","http://selleckchem.com/products/afloqualone.html","C16H14FN3O","free base","HQ-495","CC1=C(C=CC=C1)N2C(=O)C3=C(C=CC(=C3)N)N=C2CF",2.619,2,1,2]
["S3665","Trolox","g9","L4000-06","in 10mM DMSO","Vitamin","Metabolism","Trolox is a cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties.",250.29,"53188-07-1",{"v":50,"d":"50.00"},199.77,"<1","N/A","http://selleckchem.com/products/trolox.html","C14H18O4","free base","N/A","CC1=C(C)C2=C(CCC(C)(O2)C(O)=O)C(=C1O)C",3.489,2,1,1]
["S3674","Levamlodipine","h9","L4000-06","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Levamlodipine (S-amlodipine) is a pharmacologically active enantiomer of amlodipine which belongs to the dihydropyridine group of calcium channel blocker. It acts on the L-type of calcium channels and its treatment results in vasodilation and a fall in blood pressure.",408.88,"103129-82-4",{"v":81,"d":"81.00"},{"v":198.1,"d":"198.10"},{"v":81,"d":"81.00"},{"v":198.1,"d":"198.10"},"http://selleckchem.com/products/levamlodipine.html","C20H25ClN2O5","free base","S-amlodipine","CCOC(=O)C1=C(COCCN)NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C",1.576,5,2,10]
["S3682","Ethyl 3-Aminobenzoate methanesulfonate","a10","L4000-06","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Ethyl 3-Aminobenzoate (Ethyl m-Aminobenzoate, NSC 93790, Tricaine) can block the generation of action potentials via voltage-dependent Na+-channels and usually used for anesthesia, sedation, or euthanasia of fish.",261.29,"886-86-2",{"v":52,"d":"52.00"},199.01,{"v":52,"d":"52.00"},199.01,"http://selleckchem.com/products/ethyl-3-aminobenzoate-methanesulfonate.html","C9H11NO2.CH4O3S","methanesulfonate","Ethyl m-Aminobenzoate, NSC 93790, Tricaine methanesulfonate","CCOC(=O)C1=CC(=CC=C1)N.C[S](O)(=O)=O",0.873,2,1,3]
["S3684","Methacholine chloride","b10","L4000-06","in 10mM DMSO","AChR","Neuronal Signaling","Methacholine (Mecholyl, Acetyl-β-methylcholine) is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic nervous system but has little effects on the nicotinic receptors.",195.69,"62-51-1",{"v":39,"d":"39.00"},199.29,{"v":39,"d":"39.00"},199.29,"http://selleckchem.com/products/methacholine-chloride.html","C8H18NO2.Cl","chloride","Mecholyl chloride, Acetyl-β-methylcholine chloride","[Cl-].CC(C[N+](C)(C)C)OC(C)=O",-3.492,2,0,4]
["S3690","Pargyline hydrochloride","c10","L4000-06","in 10mM DMSO","MAO","Metabolism","Pargyline is an irreversible inhibitor of monoamine oxidase (MAO)-B with Ki values of 13 and 0.5 μM for time-dependent inhibition of the activity of MAO-A and -B, respectivey.",195.69,"306-07-0",{"v":39,"d":"39.00"},199.29,{"v":39,"d":"39.00"},199.29,"http://selleckchem.com/products/pargyline-hydrochloride.html","C11H13N.HCl","hydrochloride","Pargylamine hydrochloride","Cl.CN(CC#C)CC1=CC=CC=C1",3.477,0,0,3]
["S3697","Mafenide hydrochloride","d10","L4000-06","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Mafenide is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.",222.69,"138-37-4",{"v":44,"d":"44.00"},197.58,{"v":44,"d":"44.00"},197.58,"http://selleckchem.com/products/mafenide-hydrochloride.html","C7H10N2O2S.HCl","hydrochloride","4-Aminomethylbenzenesulfonamide hydrochloride","Cl.NCC1=CC=C(C=C1)[S](N)(=O)=O",0.023,2,2,2]
["S3698","Nortriptyline hydrochloride","e10","L4000-06","in 10mM DMSO","Autophagy","Autophagy","Nortriptyline hydrochloride (Desitriptyline, ELF-101, EN-7048, Desmethylamitriptyline) is the hydrochloride salt form of nortriptyline, a tricyclic antidepressant agent used for short-term treatment of various forms of depression.",299.84,"894-71-3",{"v":59,"d":"59.00"},196.77,{"v":59,"d":"59.00"},196.77,"http://selleckchem.com/products/nortriptyline-hydrochloride.html","C19H21N.HCl","hydrochloride","Desitriptyline HCl, ELF-101 hydrochloride, EN-7048 hydrochloride, Desmethylamitriptyline hydrochloride","Cl.CNCCC=C1C2=C(CCC3=C1C=CC=C3)C=CC=C2",4.618,0,1,3]
["S3700","DHBP dibromide","f10","L4000-06","in 10mM DMSO","Calcium Channel,Dyes","Transmembrane Transporters","DHBP (1,1'-diheptyl-4,4'-bipyridinium), a viologen for electrochromic memory display agent, inhibits the calcium release induced by 2 mM caffeine and 2 μg/ml polylysine with an IC50 value of 5 μg/ml and 4 μg/ml respectively.",514.38,"6159-05-3",{"v":100,"d":"100.00"},194.41,{"v":100,"d":"100.00"},194.41,"http://selleckchem.com/products/dhbp-dibromide.html","C24H38N2.2Br","dibromide","1,1'-diheptyl-4,4'-bipyridinium dibromide","[Br-].[Br-].CCCCCCC[N+]1=CC=C(C=C1)C2=CC=[N+](CCCCCCC)C=C2",3.116,0,0,13]
["S3701","Benactyzine hydrochloride","g10","L4000-06","in 10mM DMSO","AChR","Neuronal Signaling","Benactyzine hydrochloride is a centrally acting muscarinic antagonist. It is used as an antidepressant in the treatment of depression and associated anxiety.",363.88,"57-37-4",{"v":72,"d":"72.00"},197.87,{"v":72,"d":"72.00"},197.87,"http://selleckchem.com/products/benactyzine-hydrochloride.html","C20H25NO3.HCl","hydrochloride","N/A","Cl.CCN(CC)CCOC(=O)C(O)(C1=CC=CC=C1)C2=CC=CC=C2",3.832,2,0,9]
["S3704","4-Methylbenzylidene camphor","h10","L4000-06","in 10mM DMSO","Others","Others","4-Methylbenzylidene camphor (Enzacamene, 4-MBC) is an organic camphor derivative that is used in the cosmetic industry for its ability to protect the skin against UV, specifically UV B radiation.",254.37,"36861-47-9",{"v":50,"d":"50.00"},196.56,"<1","N/A","http://selleckchem.com/products/4-methylbenzylidene-camphor.html","C18H22O","free base","Enzacamene, 4-MBC","CC1=CC=C(C=C1)\\C=C/2C3CCC(C)(C2=O)C3(C)C",4.473,1,0,1]
["S3706","Sarpogrelate hydrochloride","a11","L4000-06","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Sarpogrelate (MCI-9042) is a selective 5-HT2A antagonist with pKi values of 8.52, 7.43 and 6.57 for 5-HT2A, 5-HT2C and 5-HT2B receptors respectively.",465.97,"135159-51-2",{"v":93,"d":"93.00"},199.58,{"v":93,"d":"93.00"},199.58,"http://selleckchem.com/products/sarpogrelate-hydrochloride.html","C24H31NO6.HCl","hydrochloride","MCI-9042","Cl.COC1=CC=CC(=C1)CCC2=C(OCC(CN(C)C)OC(=O)CCC(O)=O)C=CC=C2",1.427,5,0,14]
["S3716","Flibanserin","b11","L4000-06","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Flibanserin (BIMT-17, BIMT-17-BS) is a nonhormonal, centrally acting molecule that acts as an agonist at postsynaptic 5-HT1A receptors and as an antagonist at 5-HT2A receptors.",{"v":390.4,"d":"390.40"},"167933-07-5",{"v":78,"d":"78.00"},{"v":199.8,"d":"199.80"},"<1","N/A","http://selleckchem.com/products/flibanserin.html","C20H21F3N4O","free base","BIMT-17, BIMT-17-BS","FC(F)(F)C1=CC=CC(=C1)N2CCN(CC2)CCN3C(=O)NC4=C3C=CC=C4",3.609,1,1,5]
["S3723","Ramosetron Hydrochloride","c11","L4000-06","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Ramosetron Hydrochloride (YM-060) is the hydrochloride salt of ramosetron, a selective serotonin (5-HT) receptor antagonist with potential antiemetic activity.",{"v":315.8,"d":"315.80"},"132907-72-3",{"v":63,"d":"63.00"},199.49,{"v":63,"d":"63.00"},199.49,"http://selleckchem.com/products/ramosetron-hydrochloride.html","C17H17N3O.HCl","hydrochloride","YM-060","Cl.C[N]1C=C(C(=O)C2CCC3=C(C2)[NH]C=N3)C4=C1C=CC=C4",2.948,2,1,2]
["S3726","Selexipag","d11","L4000-06","in 10mM DMSO","Prostaglandin Receptor","Immunology & Inflammation","Selexipag (NS-304, ACT-293987) is an orally active, first-in-class, selective prostacyclin IP receptor agonist with Ki value of 260 nM for human IP, whereas Ki values > 10,000 nM are measured at the other human G-protein-coupled prostanoid receptors (EP1-4, DP, FP and TP).",496.62,"475086-01-2",{"v":99,"d":"99.00"},199.35,"<1","N/A","http://selleckchem.com/products/selexipag.html","C26H32N4O4S","free base","NS-304, ACT-293987","CC(C)N(CCCCOCC(=O)N[S](C)(=O)=O)C1=NC(=C(N=C1)C2=CC=CC=C2)C3=CC=CC=C3",3.996,6,1,12]
["S3727","Vilanterol Trifenate","e11","L4000-06","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Vilanterol trifenatate (GW642444M) is a novel inhaled long-acting beta2 adrenoceptor agonist with inherent 24-hour activity for once daily treatment of COPD and asthma.",774.77,"503070-58-4",{"v":100,"d":"100.00"},129.07,"<1","N/A","http://selleckchem.com/products/vilanterol-trifenate.html","C24H33Cl2NO5.C20H16O2","trifenatate","GW642444M Trifenate","OCC1=CC(=CC=C1O)C(O)CNCCCCCCOCCOCC2=C(Cl)C=CC=C2Cl.OC(=O)C(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5",5.949,3,4,20]
["S3735","Umeclidinium bromide","f11","L4000-06","in 10mM DMSO","AChR","Neuronal Signaling","Umeclidinium bromide(GSK573719A) is a long-acting muscarinic antagonist approved for the maintenance treatment of chronic obstructive pulmonary disease (COPD).",508.49,"869113-09-7",{"v":100,"d":"100.00"},196.66,"<1","N/A","http://selleckchem.com/products/umeclidinium-bromide.html","C29H34NO2.Br","bromide","GSK573719A","[Br-].OC(C1=CC=CC=C1)(C2=CC=CC=C2)C34CC[N+](CCOCC5=CC=CC=C5)(CC3)CC4",0.924,1,0,8]
["S3738","Travoprost","g11","L4000-06","in 10mM DMSO","Prostaglandin Receptor","GPCR & G Protein","Travoprost (Travoprostum) is a PGF2a analog that was launched as an ophthalmic solution administered topically for the treatment of elevated intraocular hypertension as a result of open-angle glaucoma, a common optic neuropathy, and a leading cause of blindness. It can act as an agonist of prostaglandin F receptor.",500.55,"157283-68-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/travoprost.html","C26H35F3O6","free base","Travoprostum","CC(C)OC(=O)CCC\\C=C/CC1C(O)CC(O)C1\\C=C\\C(O)COC2=CC(=CC=C2)C(F)(F)F",4.269,3,3,14]
["S3751","Quinidine hemisulfate hydrate","h11","L4000-06","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Quinidine hemisulfate hydrate(Chinidin, Pitayine, β-quinine, (+)-quinidine) acts as a blocker of voltage-gated sodium channels, also an antimuscarinic and antimalarial.",391.47,"6591-63-5",{"v":100,"d":"100.00"},154.12,{"v":9,"d":"9.00"},13.87,"http://selleckchem.com/products/quinidine-sulfate.html","C20H24N2O2.1/2H2SO4.H2O","hemisulfate hydrate","Chinidin Sodium, Pitayine Sodium, β-quinine Sodium, (+)-quinidine Sodium","O.O.COC1=CC2=C(C=C1)N=CC=C2C(O)C3CC4CCN3CC4C=C.COC5=CC6=C(C=C5)N=CC=C6C(O)C7CC8CCN7CC8C=C.O[S](O)(=O)=O",4.446,4,2,8]
["S3756","Methyl salicylate","a2","L4000-07","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Methyl salicylate (Betula oil, Gaultheria oil, Methyl 2-hydroxybenzoate, Natural wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. It is an agonist for TRPA1 and TRPV1.",152.15,"119-36-8","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/methyl-salicylate.html","C8H8O3","free base","2-Carbomethoxyphenol, Betula oil, Gaultheria oil, Methyl 2-hydroxybenzoate, Natural wintergreen oil","COC(=O)C1=C(O)C=CC=C1",1.443,2,1,2]
["S3758","Sinomenine hydrochloride","b2","L4000-07","in 10mM DMSO","Autophagy,Immunology & Inflammation related","Immunology & Inflammation","Sinomenine (SN, Cucoline, Kukoline, Sabianine A), extracted from the Chinese medicinal plant, sinomenium acutum, is a potent anti-inflammatory and neuroprotective agent.",365.85,"6080-33-7",{"v":73,"d":"73.00"},199.54,"N/A","N/A","http://selleckchem.com/products/sinomenine-hydrochloride.html","C19H23NO4.HCl","hydrochloride","Cucoline hydrochloride, Kukoline hydrochloride, Sabianine A hydrochloride","Cl.COC1=C(O)C2=C(CC3C4C=C(OC)C(=O)CC24CCN3C)C=C1",2.056,3,1,2]
["S3763","Cinnamaldehyde","c2","L4000-07","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Cinnamaldehyde is a flavonoid that is naturally synthesized by the shikimate pathway. Its supplementation can improve glucose and lipid homeostasis in diabetic animals; a TRPA1 agonist.",132.16,"14371-10-9","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/cinnamaldehyde.html","C9H8O","free base","N/A","O=C\\C=C\\C1=CC=CC=C1",1.949,1,0,2]
["S3764","Isoferulic Acid","d2","L4000-07","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Isoferulic acid (Hesperetic acid, Hesperetate, Isoferulate), a major active ingredient of Cimicifuga heracleifolia, shows anti-inflammatory, antiviral, antioxidant, and antidiabetic properties.  Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is a cinnamic acid derivative that has antidiabetic activity. Isoferulic acid binds to and activates α1-adrenergic receptors (IC50=1.4 µM) to enhance secretion of β-endorphin (EC50=52.2 nM) and increase glucose use.",194.18,"537-73-5",{"v":38,"d":"38.00"},195.69,"N/A","N/A","http://selleckchem.com/products/isoferulic-acid.html","C10H10O4","free base","Hesperetic acid, Hesperetate, Isoferulate","COC1=C(O)C=C(\\C=C\\C(O)=O)C=C1",1.669,2,1,3]
["S3766","Tanshinone IIA sulfonate sodium","e2","L4000-07","in 10mM DMSO","Calcium Channel,P2 Receptor,P450 (e.g. CYP17)","Metabolism","Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivative of tanshinone IIA isolated as the main pharmacologically active natural compound from a traditional Chinese herbal medicine, the dried root of Salvia miltiorrhiza Bunge known as Danshen. Sodium tanshinone IIA sulfonate (STS) is a potent negative allosteric modulator of the human purinergic receptor P2X7. Sodium tanshinone IIA sulfonate (STS) inhibits the activity of CYP3A4 and store-operated Ca2+ entry (SOCE) through store-operated Ca2+ channels (SOCC) via downregulating the expression of transient receptor potential canonical proteins (TRPC).",396.39,"69659-80-9",{"v":79,"d":"79.00"},{"v":199.3,"d":"199.30"},"N/A","N/A","http://selleckchem.com/products/tanshinone-iia-sulfonate-sodium.html","C19H17O6S.Na","sodium salt","N/A","[Na+].CC1=C(OC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C)[S]([O-])(=O)=O",1.873,3,0,1]
["S3769","Palmatine","f2","L4000-07","in 10mM DMSO","AChR","Neuronal Signaling","Palmatine (Berbericinine, Burasaine), an isoquinoline alkaloid, has sedative, antidepressant, antioxidative, anti-ulcerative, antacid, anticancer, and anti-metastatic activities.",{"v":352.4,"d":"352.40"},"3486-67-7",{"v":70,"d":"70.00"},198.64,"N/A","N/A","http://selleckchem.com/products/palmatine.html","C21H22NO4","free base","Berbericinine, Burasaine","COC1=CC2=C(C=C1OC)C3=CC4=C(C=[N+]3CC2)C(=C(OC)C=C4)OC",4.161,4,0,4]
["S3781","Ginkgolide C","g2","L4000-07","in 10mM DMSO","MMP","Proteases","Ginkgolide C (BN-52022), isolated from Ginkgo biloba leaves, is a flavone reported to have multiple biological functions, from decreased platelet aggregation to ameliorating Alzheimer disease. It is an activator of MMP-9.",{"v":440.4,"d":"440.40"},"15291-76-6",{"v":88,"d":"88.00"},199.82,"N/A","N/A","http://selleckchem.com/products/ginkgolide-c.html","C20H24O11","free base","BN-52022","CC1C(=O)OC2C(O)C34C5OC(=O)C3(OC6OC(=O)C(O)C46C(C5O)C(C)(C)C)C12O",-1.753,7,3,1]
["S3783","Echinacoside","h2","L4000-07","in 10mM DMSO","Tyrosinase","Protein Tyrosine Kinase","Echinacoside, a natural polyphenolic compound, has various biological activities, such as antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative actions. Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche salsa, elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Echinacoside also has a remarkable antiosteoporotic activity.",786.73,"82854-37-3",{"v":100,"d":"100.00"},127.11,"N/A","N/A","http://selleckchem.com/products/echinacoside.html","C35H46O20","free base","N/A","CC1OC(OC2C(O)C(OCCC3=CC(=C(O)C=C3)O)OC(COC4OC(CO)C(O)C(O)C4O)C2OC(=O)\\C=C\\C5=CC=C(O)C(=C5)O)C(O)C(O)C1O",-1.263,8,12,14]
["S3785","Notoginsenoside R1","a3","L4000-07","in 10mM DMSO","Akt,ERK,PAI-1,PI3K","Metabolism","Notoginsenoside R1 (Sanchinoside R1) is the main ingredient with cardiovascular activity in Panax notoginseng. It inhibits TNF-α-induced PAI-1 overexpression via extracellular signal-related kinases (ERK1/2) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling pathways.",933.13,"80418-24-2",{"v":100,"d":"100.00"},107.17,"N/A","N/A","http://selleckchem.com/products/notoginsenoside-r1.html","C47H80O18","free base","Sanchinoside R1, NG-R1, NGR1","CC(C)=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C2CCC3(C)C2C(O)CC4C5(C)CCC(O)C(C)(C)C5C(CC34C)OC6OC(CO)C(O)C(O)C6OC7OCC(O)C(O)C7O",{"v":-0.11,"d":"-0.110"},6,12,12]
["S3786","Glabridin","b3","L4000-07","in 10mM DMSO","GABA Receptor,PPAR","Metabolism","Glabridin (Q-100692, KB-289522, LS-176045), one of the active phytochemicals in licorice extract, binds to and activates the ligand binding domain of PPARγ, as well as the full length receptor. It is also a GABAA receptor positive modulator promoting fatty acid oxidation and improving learning and memory.",324.37,"59870-68-7",{"v":64,"d":"64.00"},197.31,"N/A","N/A","http://selleckchem.com/products/glabridin.html","C20H20O4","free base","Q-100692, KB-289522, LS-176045","CC1(C)OC2=C(C=C1)C3=C(CC(CO3)C4=CC=C(O)C=C4O)C=C2",3.999,2,2,1]
["S3788","Carvacrol","c3","L4000-07","in 10mM DMSO","AChR","Neuronal Signaling","Carvacrol (Cymophenol), monoterpenic phenol isomeric with thymol, has diverse activities such as antimicrobial, antitumor, an-timutagenic, antigenotoxic, analgesic, antispasmodic, anti-inflammatory, angiogenic, antiparasitic, antiplatelet, AChE inhibitory, antielastase, insecticidal, antihepatotoxic and hepatoprotective activities.",150.22,"499-75-2","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/carvacrol.html","C10H14O","free base","cymophenol","CC(C)C1=CC=C(C)C(=C1)O",3.268,0,1,1]
["S3791","Succinic acid","d3","L4000-07","in 10mM DMSO","Others","Metabolism","Succinic acid (1,4-Butandioic Acid, 1,2-Ethanedicarboxylic acid, Amber acid, Asuccin, Butanedioic acid) is a crystalline organic acid which occurs in living tissue as an intermediate in glucose metabolism.",118.09,"110-15-6",{"v":23,"d":"23.00"},194.77,"N/A","N/A","http://selleckchem.com/products/succinic-acid.html","C4H6O4","free base","1,4-Butandioic Acid, 1,2-Ethanedicarboxylic acid, Amber acid, Asuccin, Butanedioic acid","OC(=O)CCC(O)=O",{"v":-0.36,"d":"-0.360"},2,0,3]
["S3797","Helicide","e3","L4000-07","in 10mM DMSO","Others","Others","Helicide (4-formylphenyl-O-β-d-allopyranoside), a main active constituent from seeds of the Chinese herb Helicia nilagirica, has been reported to exert a sedative, analgesic and hypnotic effect, and is used clinically to treat neurasthenic syndrome, vascular headaches and trigeminal neuralgia.",284.26,"80154-34-3",{"v":56,"d":"56.00"},{"v":197,"d":"197.00"},"N/A","N/A","http://selleckchem.com/products/helicide.html","C13H16O7","free base","4-formylphenyl-O-β-d-allopyranoside","OCC1OC(OC2=CC=C(C=O)C=C2)C(O)C(O)C1O",-0.583,3,4,4]
["S3800","Lycorine hydrochloride","f3","L4000-07","in 10mM DMSO","ADC Cytotoxin,HCV Protease","Proteases","Lycorine (Galanthidine, Amarylline, Narcissine, Licorine), a natural alkaloid extracted from the Amaryllidaceae plant family, has been reported to exhibit a wide range of physiological effects, including the potential effect against cancer. It is an HCV inhibitor with strong activity.",323.77,"2188-68-3",{"v":64,"d":"64.00"},197.67,"N/A","N/A","http://selleckchem.com/products/lycorine-hydrochloride.html","C16H17NO4.HCl","hydrochloride","Galanthidine hydrochloride, Amarylline hydrochloride, Narcissine hydrochloride, Licorine hydrochloride","Cl.OC1C=C2CCN3CC4=C(C=C5OCOC5=C4)C(C1O)C23",1.095,2,2,0]
["S3802","Trigonelline Hydrochloride","g3","L4000-07","in 10mM DMSO","Bacterial","Microbiology","Trigonelline (Nicotinic acid N-methylbetaine, Coffearine, Gynesine), a major alkaloid component of fenugreek, has hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities, and also has been shown to reduce diabetic auditory neuropathy and platelet aggregation.",{"v":173.6,"d":"173.60"},"6138-41-6",{"v":18,"d":"18.00"},103.69,"N/A","N/A","http://selleckchem.com/products/trigonelline-hydrochloride.html","C7H8NO2.Cl","chloride","Nicotinic acid N-methylbetaine Hydrochloride, Coffearine Hydrochloride, Gynesine Hydrochloride","[Cl-].C[N+]1=CC(=CC=C1)C(O)=O",{"v":-1.61,"d":"-1.610"},1,0,1]
["S3809","Imperatorin","h3","L4000-07","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Imperatorin (Ammidin, Marmelosin, Pentosalen, 8-Isoamylenoxypsoralen), a naturally occurring psoralen-type furanocoumarin, is a potent myorelaxant agent and acts as a calcium antagonist on vascular smooth muscle.",270.28,"482-44-0",{"v":54,"d":"54.00"},199.79,"N/A","N/A","http://selleckchem.com/products/imperatorin.html","C16H14O4","free base","Ammidin, Marmelosin, Pentosalen, 8-Isoamylenoxypsoralen, 8-Isopentenyloxypsoralene","CC(C)=CCOC1=C2OC(=O)C=CC2=CC3=C1OC=C3",3.652,4,0,3]
["S3811","Ginsenoside Re","a4","L4000-07","in 10mM DMSO","Beta Amyloid,JNK,NF-κB","Neuronal Signaling","Ginsenoside Re (Ginsenoside B2, Panaxoside Re, Sanchinoside Re, Chikusetsusaponin Ivc), an extract from Panax notoginseng, is a major ginsenoside in ginseng and belongs to 20(S)-protopanaxatriol group. It has diverse in vitro and in vivo effects, including vasorelaxant, antioxidant, antihyperlipidemic, and angiogenic actions. Ginsenoside Re decreases the β-amyloid protein (Aβ). Ginsenoside Re plays a role in antiinflammation through inhibition of JNK and NF-κB.",947.15,"52286-59-6",{"v":100,"d":"100.00"},105.58,"N/A","N/A","http://selleckchem.com/products/ginsenoside-re.html","C48H82O18","free base","Panaxoside Re, Sanchinoside Re, Chikusetsusaponin Ivc","CC1OC(OC2C(O)C(O)C(CO)OC2OC3CC4(C)C(CC(O)C5C(CCC45C)C(C)(CCC=C(C)C)OC6OC(CO)C(O)C(O)C6O)C7(C)CCC(O)C(C)(C)C37)C(O)C(O)C1O",0.267,6,12,12]
["S3816","Dehydroevodiamine","b4","L4000-07","in 10mM DMSO","COX,NF-κB,PGES,ROS","Immunology & Inflammation","Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood flow enhancing activities. Dehydroevodiamine inhibits LPS-induced iNOS, COX-2, prostaglandin E2 (PGE2) and nuclear factor-kappa B (NF-κB) expression in murine macrophage cells.",301.34,"67909-49-3",{"v":19,"d":"19.00"},63.05,"N/A","N/A","http://selleckchem.com/products/dehydroevodiamine.html","C19H15N3O","inner salt","DHED","C[N+]1=C2N(CCC3=C2[N-]C4=C3C=CC=C4)C(=O)C5=C1C=CC=C5",3.186,1,0,0]
["S3817","Harmine hydrochloride","c4","L4000-07","in 10mM DMSO","5-HT Receptor,ADC Cytotoxin,DYRK,MAO","Cell Cycle","Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγ and cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.",248.71,"343-27-1",{"v":21,"d":"21.00"},84.44,"N/A","N/A","http://selleckchem.com/products/harmine-hydrochloride.html","C13H12N2O.HCl","hydrochloride","Telepathine hydrochloride","Cl.COC1=CC2=C(C=C1)C3=CC=NC(=C3[NH]2)C",{"v":2.82,"d":"2.820"},2,1,1]
["S3820","Dehydroevodiamine hydrochloride","d4","L4000-07","in 10mM DMSO","AChR","Neuronal Signaling","Dehydroevodiamine (DHE), a major phytochemical in fruits of Evodia rutaecarpa, can inhibit AChE. It has hypotensive and neuroprotective effects and modulates nitric oxide production.",{"v":337.8,"d":"337.80"},"111664-82-5",{"v":37,"d":"37.00"},109.53,"N/A","N/A","http://selleckchem.com/products/dehydroevodiamine-hydrochloride.html","C19H15N3O.HCl","hydrochloride","N/A","Cl.CN1C2=CC=CC=C2C(=O)N3CCC4=C5C=CC=CC5=NC4=C13",2.891,2,0,0]
["S3823","Schizandrol A","e4","L4000-07","in 10mM DMSO","Others","Neuronal Signaling","Schizandrol A is one of the effective components in the dried fruit of Schizandra chinensis Bail and works by increasing dopamine, a neurotransmitter, in the brain.",432.51,"7432-28-2",{"v":86,"d":"86.00"},198.84,"N/A","N/A","http://selleckchem.com/products/schizandrol-a.html","C24H32O7","free base","N/A","COC1=CC2=C(C(=C1OC)OC)C3=C(CC(C)(O)C(C)C2)C=C(OC)C(=C3OC)OC",{"v":4.05,"d":"4.050"},6,0,6]
["S3828","Orcinol glucoside","f4","L4000-07","in 10mM DMSO","Others","Others","Orcinol glucoside (OG, Sakakin) is an active constituent isolated from the rhizomes of Curculigo orchioides Gaertn. It shows potent antioxidative and anxiolytic activities without sedative effects.",286.28,"21082-33-7",{"v":58,"d":"58.00"},{"v":202.6,"d":"202.60"},"N/A","N/A","http://selleckchem.com/products/orcinol-glucoside.html","C13H18O7","free base","Sakakin","CC1=CC(=CC(=C1)OC2OC(CO)C(O)C(O)C2O)O",-0.098,2,5,3]
["S3833","Amentoflavone","g4","L4000-07","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Amentoflavone (Didemethyl Ginkgetin) is a biflavonoid originally isolated from Selaginella with antibacterial, antioxidant, antiviral, antidiabetic, and neuroprotective activities.",538.46,"1617-53-4",{"v":100,"d":"100.00"},185.71,"N/A","N/A","http://selleckchem.com/products/amentoflavone.html","C30H18O10","free base","Didemethyl Ginkgetin","OC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(O)C=C3O)C4=CC(=CC=C4O)C5=CC(=O)C6=C(O5)C=C(O)C=C6O",4.509,4,6,3]
["S3834","Astaxanthin","h4","L4000-07","in 10mM DMSO","PPAR","Metabolism","Astaxanthin (β-Carotene-4,4'-dione, Trans-Astaxanthin), a xanthophyll carotenoid, is a nutrient with unique cell membrane actions and diverse clinical benefits with excellent safety and tolerability. Astaxanthin, a red dietary carotenoid isolated from Haematococcus pluvialis, is a modulator of PPARγ and a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity.",596.84,"472-61-7",{"v":100,"d":"100.00"},167.55,"N/A","N/A","http://selleckchem.com/products/astaxanthin.html","C40H52O4","free base","β-Carotene-4,4'-dione, Trans-Astaxanthin","CC(=C\\C=C\\C=C(C)\\C=C\\C=C(C)\\C=C\\C1=C(C)C(=O)C(O)CC1(C)C)/C=C/C=C(C)/C=C/C2=C(C)C(=O)C(O)CC2(C)C",8.421,2,2,10]
["S3835","Loganin","a5","L4000-07","in 10mM DMSO","AChR,BACE,BChE","Neuronal Signaling","Loganin (Loganoside) is an iridoid glycoside first isolated from the seeds of Strychnos nux-vomica, a member of the Loganiaceae family. It is a non-competitive inhibitor of BACE1 with IC50 of 47.97 μM an also inhibits AChE and BChE with IC50 values of 3.95 μM and 33.02 μM, respectively.",390.38,"18524-94-2",{"v":78,"d":"78.00"},199.81,"N/A","N/A","http://selleckchem.com/products/loganin.html","C17H26O10","free base","Loganoside","COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C3C(C)C(O)CC13",-1.895,5,5,5]
["S3841","Eleutheroside B","b5","L4000-07","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Eleutheroside B (syringin, Syringoside, Lilacin) is a phenylpropanoid glycoside first isolated from A. senticosus and has neuroprotective, tonic, adaptogenic, and immune-modulating properties.",372.37,"118-34-3",{"v":74,"d":"74.00"},198.73,"N/A","N/A","http://selleckchem.com/products/eleutheroside-b.html","C17H24O9","free base","syringin, Syringoside, Lilacin","COC1=CC(=CC(=C1OC2OC(CO)C(O)C(O)C2O)OC)\\C=C\\CO",-0.512,4,5,7]
["S3844","Rosavin","c5","L4000-07","in 10mM DMSO","Others","Others","Rosavin, a cinnamyl alcohol glycoside found in the plant Rhodiola rosea, possesses antidepressant and anxiolytic activities.",428.43,"84954-92-7",{"v":85,"d":"85.00"},{"v":198.4,"d":"198.40"},"N/A","N/A","http://selleckchem.com/products/rosavin.html","C20H28O10","free base","N/A","OC1COC(OCC2OC(OC\\C=C\\C3=CC=CC=C3)C(O)C(O)C2O)C(O)C1O",{"v":-1.29,"d":"-1.290"},4,6,7]
["S3851","Camphor","d5","L4000-07","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Camphor (2-Bornanone, Bornan-2-one, 2-Camphanone, Formosa) is a bicyclic monoterpene ketone found widely in plants, especially cinnamomum camphora and used topically as a skin antipruritic and as an anti-infective agent.",152.23,"76-22-2",{"v":30,"d":"30.00"},197.07,"N/A","N/A","http://selleckchem.com/products/camphor.html","C10H16O","free base","2-Bornanone, Bornan-2-one, 2-Camphanone, Formosa","CC1(C)C2CCC1(C)C(=O)C2",2.075,1,0,0]
["S3854","Tetrahydropalmatine hydrochloride","e5","L4000-07","in 10mM DMSO","ADC Cytotoxin,Dopamine Receptor","Neuronal Signaling","Tetrahydropalmatine (THP, Gindarine, 1-Tetrahydropalmitine) is an isoquinoline alkaloid found in several different plant species, mainly in the Corydalis genus (Yan Hu Suo), but also in other plants such as Stephania rotunda. It is a potent  muscle relaxant. Tetrahydropalmatine hydrochloride acts through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats.",391.89,"6024-85-7",{"v":12,"d":"12.00"},30.62,"N/A","N/A","http://selleckchem.com/products/tetrahydropalmatine-hydrochloride.html","C21H25NO4.HCl","hydrochloride","Gindarine hydrochloride, 1-Tetrahydropalmitine HCl","Cl.COC1=C(OC)C2=C(CC3N(CCC4=C3C=C(OC)C(=C4)OC)C2)C=C1",3.981,4,0,4]
["S3855","Ethyl ferulate","f5","L4000-07","in 10mM DMSO","Others","Others","Ethyl ferulate (Ferulic acid ethyl ester) is the alkyl ester derivative of ferulic acid which is a naturally occurring plant product with anti-oxidative, anti-inflammatory, neuroprotective, and antiproliferative activities.",222.24,"4046-02-0",{"v":44,"d":"44.00"},197.98,"N/A","N/A","http://selleckchem.com/products/ethyl-ferulate.html","C12H14O4","free base","Ferulic acid ethyl ester, Ethyl 4'-hydroxy-3'-methoxycinnamate, Ethyl 3-(4-hydroxy-3-methoxyphenyl)acrylate","CCOC(=O)/C=C/C1=CC(=C(O)C=C1)OC",2.243,3,1,5]
["S3856","Allantoin","g5","L4000-07","in 10mM DMSO","Others","Others","Allantoin (Glyoxyldiureide, 5-Ureidohydantoin), produced from uric acid, is a major metabolic intermediate in most organisms including animals, plants and bacteria.",158.12,"97-59-6",{"v":7,"d":"7.00"},44.27,"N/A","N/A","http://selleckchem.com/products/allantoin.html","C4H6N4O3","free base","Glyoxyldiureide, 5-Ureidohydantoin","NC(=O)NC1NC(=O)NC1=O",{"v":-1.76,"d":"-1.760"},3,4,1]
["S3857","4-Hydroxybenzyl alcohol","h5","L4000-07","in 10mM DMSO","Apoptosis related","Apoptosis","4-hydroxybenzyl alcohol (P-Methylolphenol, 4-Methylolphenol), an important phenolic constituent of Gastrodia elata Blume (GEB), has been shown to have many beneficial effects in different animal models of neurological disorders, such as, headaches, convulsive behavior, dizziness, and vertigo.",124.14,"623-05-2",{"v":24,"d":"24.00"},193.33,"N/A","N/A","http://selleckchem.com/products/4-hydroxybenzyl-alcohol.html","C7H8O2","free base","P-Methylolphenol, 4-Methylolphenol","OCC1=CC=C(O)C=C1",0.983,0,2,1]
["S3865","Taurochenodeoxycholic acid","a6","L4000-07","in 10mM DMSO","Caspase,TNF-alpha","Apoptosis","Taurochenodeoxycholic acid (Taurochenodeoxycholate, TCDCA, Chenodeoxycholyltaurine), a bile acid formed in the liver of most species, is used as a cholagogue and choleretic.",{"v":499.7,"d":"499.70"},"516-35-8",{"v":99,"d":"99.00"},198.12,"N/A","N/A","http://selleckchem.com/products/taurochenodeoxycholic-acid.html","C26H45NO6S","free base","Taurochenodeoxycholate, TCDCA, 12-Deoxycholyltaurine, Chenodeoxycholyltaurine, Chenyltaurine","CC(CCC(=O)NCC[S](O)(=O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C",2.997,1,3,7]
["S3866","Galanthamine","b6","L4000-07","in 10mM DMSO","AChR","Neuronal Signaling","Galanthamine (Galantamine, Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is a phenanthrene alkaloid and a reversible, competitive acetylcholinesterase inhibitor with IC50 of 0.35 μM, exhibits 50-fold selectivity against butyryl-cholinesterase. It is studied as a treatment for Alzheimer's disease and other central nervous system disorders.",287.35,"357-70-0",{"v":100,"d":"100.00"},348.01,{"v":57,"d":"57.00"},198.36,"http://selleckchem.com/products/galanthamine.html","C17H21NO3","free base","Galantamine, Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine","COC1=C2OC3CC(O)C=CC34CCN(C)CC(=C24)C=C1",1.442,2,1,1]
["S3867","(E)-Cardamonin","c6","L4000-07","in 10mM DMSO","NF-κB,TRP Channel","NF-κB","(E)-Cardamonin (Alpinetin chalcone, cardamomin) is a naturally occurring chalcone with strong anti-inflammatory activity. It is a novel TRPA1 antagonist with IC50 of 454 nM and also a NF-kB inhibitor.",270.28,"19309-14-9",{"v":54,"d":"54.00"},199.79,"N/A","N/A","http://selleckchem.com/products/e-cardamoni.html","C16H14O4","free base","Alpinetin chalcone, cardamomin","COC1=CC(=CC(=C1C(=O)\\C=C\\C2=CC=CC=C2)O)O",3.201,2,2,4]
["S3868","Harmine","d6","L4000-07","in 10mM DMSO","MAO,PPAR","Metabolism","Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγ and cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.",212.25,"442-51-3",{"v":42,"d":"42.00"},197.88,"N/A","N/A","http://selleckchem.com/products/harmine.html","C13H12N2O","free base","Telepathine","COC1=CC2=C(C=C1)C3=CC=NC(=C3[NH]2)C",2.438,2,1,1]
["S3872","Guaiacol","e6","L4000-07","in 10mM DMSO","COX,NF-κB","NF-κB","Guaiacol (O-methoxyphenol, 2-hydroxyanisole, O-methylcatechol) is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. It is a precursor to various flavorants, such as eugenoland vanillin. Guaiacol, a phenolic compound isolated from Guaiac resin, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Anti-inflammatory activity.",124.14,"90-05-1",{"v":24,"d":"24.00"},193.33,"N/A","N/A","http://selleckchem.com/products/guaiacol.html","C7H8O2","free base","o-methoxyphenol, 2-hydroxyanisole, O-methylcatechol","COC1=C(O)C=CC=C1",1.571,1,1,1]
["S3874","Curcumenol","f6","L4000-07","in 10mM DMSO","NF-κB,P450 (e.g. CYP17)","NF-κB","Curcumenol, a sesquiterpene isolated from Curcuma zedoaria, is known to possess a variety of health and medicinal values which includes neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. It inhibits NF-κB activation by suppressing the nuclear translocation of the NF-κB p65 subunit and blocking IκBα phosphorylation and degradation.",234.33,"19431-84-6",{"v":46,"d":"46.00"},{"v":196.3,"d":"196.30"},"N/A","N/A","http://selleckchem.com/products/curcumenol.html","C15H22O2","free base","N/A","CC1CCC2C(=CC3(O)OC12CC3=C(C)C)C",3.268,1,0,0]
["S3880","Schisantherin A","g6","L4000-07","in 10mM DMSO","NF-κB","NF-κB","Schisantherin A (Gomisin C, Schisanwilsonin H, Arisanschinin K) is a dibenzocyclooctadiene that exhibits anti-tussive, sedative, anti-inflammatory, anti-osteoporotic, neuroprotective, cognition enhancing, and cardioprotective activities. Schisantherin A inhibits p65-NF-κB translocation into the nucleus by IκBα degradation.",536.57,"58546-56-8",{"v":100,"d":"100.00"},186.37,"N/A","N/A","http://selleckchem.com/products/schisantherin-a.html","C30H32O9","free base","Gomisin C, Schisanwilsonin H, Arisanschinin K","COC1=CC2=C(C(=C1OC)OC)C3=C(CC(C)C(C)(O)C2OC(=O)C4=CC=CC=C4)C=C5OCOC5=C3OC",5.063,8,0,7]
["S3881","Scopoletin","h6","L4000-07","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Scopoletin (Esculetin 6-methyl ether, Gelseminic acid, 6-Methylesculetin, Chrysatropic acid) is the main bioactive constituent of flower buds from Magnolia fargesii with anti-inflammatory, hypouricemic, and antioxidant activities.",192.17,"92-61-5",{"v":38,"d":"38.00"},197.74,"N/A","N/A","http://selleckchem.com/products/scopoletin.html","C10H8O4","free base","Esculetin 6-methyl ether, Gelseminic acid, 6-Methylesculetin, Chrysatropic acid","COC1=CC2=C(OC(=O)C=C2)C=C1O",1.641,3,1,1]
["S3883","Protopine","a7","L4000-07","in 10mM DMSO","ADC Cytotoxin,Calcium Channel","Transmembrane Transporters","Protopine (Corydinine, Fumarine, Biflorine, Macleyine), an alkaloid present in different plants, has been shown to exhibit a number of activities, such as inhibition of calcium influx through both voltage and receptor-operated channels and inhibition of rabbit blood platelet aggregation. It also possesses anti-cholinergic and anti-histaminic as well as anti-bacterial activities.",353.37,"130-86-9",{"v":30,"d":"30.00"},{"v":84.9,"d":"84.90"},"N/A","N/A","http://selleckchem.com/products/protopine.html","C20H19NO5","free base","Corydinine, Fumarine, Biflorine, Macleyine","CN1CCC2=C(C=C3OCOC3=C2)C(=O)CC4=C(C1)C5=C(OCO5)C=C4",2.953,5,0,0]
["S3884","Jatrorrhizine","b7","L4000-07","in 10mM DMSO","AChR","Neuronal Signaling","Jatrorrhizine (Neprotin, Yatrorizine), one of the active constituents of Coptis chinensis Franch, has multiple bioactivities, such as hypoglycemic, antimicrobial, and antioxidant activities. It is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.",338.38,"3621-38-3",{"v":67,"d":"67.00"},{"v":198,"d":"198.00"},"N/A","N/A","http://selleckchem.com/products/jatrorrhizine.html","C20H20NO4","free base","Neprotin, Yatrorizine","COC1=CC2=C(CC[N+]3=CC4=C(C=CC(=C4OC)OC)C=C23)C=C1O",3.936,3,1,3]
["S3886","Quinic acid","c7","L4000-07","in 10mM DMSO","NF-κB","Immunology & Inflammation","Quinic acid (Chinic acid, Kinic acid) is a crystalline acid obtained from cinchona bark, coffee beans, and other plant products and made synthetically by hydrolysis of chlorogenic acid.",192.17,"77-95-2",{"v":38,"d":"38.00"},197.74,"N/A","N/A","http://selleckchem.com/products/quinic-acid.html","C7H12O6","free base","Chinic acid, Kinic acid","OC1CC(O)(CC(O)C1O)C(O)=O",-2.367,1,3,1]
["S3894","Cycloastragenol","d7","L4000-07","in 10mM DMSO","Telomerase","DNA Damage/DNA Repair","Cycloastragenol (CAG, TA-65, Cyclogalegigenin, Astramembrangenin) is a saponin comprising a group of oil glucosides naturally present in a number of plants. It is a potent telomerase activator in neuronal cells.",490.72,"84605-18-5",{"v":98,"d":"98.00"},199.71,"N/A","N/A","http://selleckchem.com/products/cycloastragenol.html","C30H50O5","free base","CAG, TA-65, Cyclogalegigenin, Astramembrangenin","CC(C)(O)C1CCC(C)(O1)C2C(O)CC3(C)C4CC(O)C5C(C)(C)C(O)CCC56CC46CCC23C",2.635,1,3,2]
["S3895","Sophoridine","e7","L4000-07","in 10mM DMSO","Apoptosis related","Apoptosis","Sophoridine (5-Epidihydrosophocarpine, Dihydro-5-episophocarpine), a natural product obtained from medicinal plants, has a variety of pharmacological effects, including anti-cancer and anti-arrhythmia, and affects the immune and central nervous systems.",248.36,"6882-68-4",{"v":49,"d":"49.00"},197.29,"N/A","N/A","http://selleckchem.com/products/sophoridine.html","C15H24N2O","free base","5-Epidihydrosophocarpine, Dihydro-5-episophocarpine","O=C1CCCC2C3CCCN4CCCC(CN12)C34",1.417,1,0,0]
["S3899","Hederagenin","f7","L4000-07","in 10mM DMSO","COX,NF-κB,NOS","Immunology & Inflammation","Hederagenin (Caulosapogenin, Hederagenol, Hederagenic acid, Astrantiagenin E) is a highly water insoluble triterpenoid compound that can be found in various plants including Hedera helix and Chenopodium quinoa. It exhibits a variety of biological activities, including potent antitumor properties both in vitro and in vivo. Hederagenin inhibits LPS-stimulated expression of iNOS, COX-2, and NF-κB.",{"v":472.7,"d":"472.70"},"465-99-6",{"v":94,"d":"94.00"},198.86,"N/A","N/A","http://selleckchem.com/products/hederagenin.html","C30H48O4","free base","Caulosapogenin, Hederagenol, Hederagenic acid, Astrantiagenin E","CC1(C)CCC2(CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(CO)C5CCC34C)C2C1)C(O)=O",5.356,1,2,2]
["S3901","Astragaloside IV","g7","L4000-07","in 10mM DMSO","Akt,ERK,JNK,mTOR,NF-κB","MAPK","Astragaloside IV (AST-IV, AS-IV) is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine. It has various effect on the cardiovascular, immune, digestive, and nervous systems. AS-IV suppresses activation of p-Akt, p-mTOR, p-NF-κB and p-Erk1/2.",784.97,"84687-43-4",{"v":100,"d":"100.00"},127.39,"N/A","N/A","http://selleckchem.com/products/sastragaloside-iv.html","C41H68O14","free base","AST-IV, AS-IV","CC(C)(O)C1CCC(C)(O1)C2C(O)CC3(C)C4CC(OC5OC(CO)C(O)C(O)C5O)C6C(C)(C)C(CCC67CC47CCC23C)OC8OCC(O)C(O)C8O",-0.348,5,8,7]
["S3902","Ursonic acid","h7","L4000-07","in 10mM DMSO","Others","Apoptosis","Ursonic acid (Prunol, Malol, beta-Ursolic acid, NSC4060, CCRIS 7123, TOS-BB-0966), present in many plants, is a pentacyclic triterpenoid that can be used as a cosmetics additive and serve as a starting material for synthesis of more potent bioactive derivatives, such as experimental antitumor agents. Ursonic acid induces the apoptosis of human cancer cells through multiple signaling pathways.",454.68,"6246-46-4",{"v":30,"d":"30.00"},65.98,"N/A","N/A","http://selleckchem.com/products/ursonic-acid.html","C30H46O3","free base","Prunol, Malol, beta-Ursolic acid, NSC4060, CCRIS 7123, TOS-BB-0966, 3-beta-hydroxyurs-12-en-28-oic acid","CC1CCC2(CCC3(C)C(=CCC4C5(C)CCC(=O)C(C)(C)C5CCC34C)C2C1C)C(O)=O",6.593,2,0,1]
["S3903","Lycorine","a8","L4000-07","in 10mM DMSO","AChR","Neuronal Signaling","Lycorine (Galanthidine, Amarylline, Narcissine, Licorine, Belamarine) is a toxic crystalline alkaloid found in various Amaryllidaceae species that weakly inhibits acetylcholinesterase (AChE) and ascorbic acid biosynthesis.",287.31,"476-28-8",{"v":57,"d":"57.00"},198.39,"N/A","N/A","http://selleckchem.com/products/lycorine.html","C16H17NO4","free base","Galanthidine, Amarylline, Narcissine, Licorine, Belamarine","OC1C=C2CCN3CC4=CC5=C(OCO5)C=C4C(C1O)C23",0.713,2,2,0]
["S3904","Isoimperatorin","b8","L4000-07","in 10mM DMSO","AChR","Neuronal Signaling","Isoimperatorin, a natural furanocoumarin that can be isolated from a variety of plant parts, has analgesic, antimicrobial, vascular relaxing and anticancer activities.  Isoimperatorin is a methanolic extract of the roots of Angelica dahurica shows significant inhibitory effects on acetylcholinesterase (AChE) with the IC50 of 74.6 μM.",270.28,"482-45-1",{"v":54,"d":"54.00"},199.79,"N/A","N/A","http://selleckchem.com/products/isoimperatorin.html","C16H14O4","free base","N/A","CC(C)=CCOC1=C2C=COC2=CC3=C1C=CC(=O)O3",3.652,4,0,3]
["S3907","Bulleyaconi cine A","c8","L4000-07","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Bulleyaconi cine A (Bulleyaconitine A, BLA) is an active ingredient of Aconitum bulleyanum plants and classified as an \"aconitine-like\" alkaloid. It is a potent use-dependent blocker for both Nav1.7 and Nav1.8 Na+ currents.",627.76,"107668-79-1",{"v":7,"d":"7.00"},11.15,"N/A","N/A","http://selleckchem.com/products/bulleyaconi-cine-a.html","C35H49NO9","free base","Bulleyaconitine A","CCN1CC2(CCC(OC)C34C5CC6(O)C(CC(OC(C)=O)(C(C(OC)C23)C14)C5C6C(=O)C7=CC=C(OC)C=C7)OC)COC",0.816,8,0,11]
["S3909","Catalpol","d8","L4000-07","in 10mM DMSO","Others","Others","Catalpol (Catalpinoside, Digitalis purpurea L), an iridoid glucoside contained richly in the roots of the small flowering plant species Rehmannia glutinosa Libosch, has been shown to have antioxidation, anti-inflammation, anti-apoptosis and other neuroprotective properties and plays a role in neuroprotection against hypoxic/ischemic injury, AD and PD in both in vivo and in vitro models.",362.33,"2415-24-9",{"v":72,"d":"72.00"},198.71,"N/A","N/A","http://selleckchem.com/products/catalpol.html","C15H22O10","free base","Catalpinoside, Digitalis purpurea L","OCC1OC(OC2OC=CC3C(O)C4OC4(CO)C23)C(O)C(O)C1O",-3.581,4,6,4]
["S3911","Veratramine","e8","L4000-07","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Veratramine (NSC 17821, NSC 23880), a major alkaloid from Veratrum nigrum L., has distinct anti-tumor and anti-hypertension effects. It is a good membrane permeant, undergoes rapid passive diffusion, and has a good stability in the gastrointestinal tract during its absorption.",{"v":409.6,"d":"409.60"},"60-70-8",{"v":63,"d":"63.00"},153.81,"N/A","N/A","http://selleckchem.com/products/veratramine.html","C27H39NO2","free base","NSC 17821, NSC 23880","CC1CNC(C(O)C1)C(C)C2=CC=C3C4CC=C5CC(O)CCC5(C)C4CC3=C2C",4.657,0,3,2]
["S3923","Ginsenoside Rg1","f8","L4000-07","in 10mM DMSO","Beta Amyloid,NF-κB","Neuronal Signaling","Ginsenoside Rg1 (Ginsenoside A2, Panaxoside A, Panaxoside Rg1, Sanchinoside C1, Sanchinoside Rg1), one of the major active components of ginseng, is identified as a protopanaxatriol-type and has pharmacological actions such as neuroprotective and anti-tumor effects on various cancer types. Ginsenoside Rg1 reduces cerebral Aβ levels and NF-κB nuclear translocation.",801.01,"22427-39-0",{"v":100,"d":"100.00"},124.84,"N/A","N/A","http://selleckchem.com/products/ginsenoside-rg1.html","C42H72O14","free base","Ginsenoside A2, Panaxoside A, Panaxoside Rg1, Sanchinoside C1, Sanchinoside Rg1","CC(C)=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C2CCC3(C)C2C(O)CC4C5(C)CCC(O)C(C)(C)C5C(CC34C)OC6OC(CO)C(O)C(O)C6O",1.126,4,10,10]
["S3924","Ginsenoside Rb1","g8","L4000-07","in 10mM DMSO","ATPase,IFN,IRAK,NF-κB,NOS,TLR,TNF-alpha","Transmembrane Transporters","Ginsenoside Rb1 (Gypenoside Ⅲ) is a protopanaxadiol that has diverse in vitro and in vivo effects, including neuroprotective, anti-inflammatory, and anti-obesity actions. Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65. Ginsenoside Rb1 reduces the expressions of TLR3, TLR4 and TRAF-6, and down-regulates the levels of TNF-α, IFN-β and iNOS.",1109.29,"41753-43-9",{"v":100,"d":"100.00"},90.15,"N/A","N/A","http://selleckchem.com/products/ginsenoside-rb1.html","C54H92O23","free base","Gypenoside Ⅲ","CC(C)=CCCC(C)(OC1OC(COC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CCC45C",-1.198,8,15,16]
["S3925","(-)-Epicatechin gallate","h8","L4000-07","in 10mM DMSO","COX","Immunology & Inflammation","(-)-Epicatechin gallate (ECG) is an inhibitor of cyclooxygenase-1 (COX-1) with IC50 of 7.5 μM.",442.37,"1257-08-5",{"v":88,"d":"88.00"},198.93,"N/A","N/A","http://selleckchem.com/products/epicatechin-gallate.html","C22H18O10","free base","(−)-ECG, (−)-Epicatechin 3-gallate, (−)-Epicatechin-3-O-gallate","OC1=CC2=C(CC(OC(=O)C3=CC(=C(O)C(=C3)O)O)C(O2)C4=CC=C(O)C(=C4)O)C(=C1)O",3.339,3,7,4]
["S3931","Ginsenoside Rd","a9","L4000-07","in 10mM DMSO","Calcium Channel,COX,NF-κB,NOS,P450 (e.g. CYP17)","Immunology & Inflammation","Ginsenoside Rd (Panaxoside Rd, Sanchinoside Rd), a minor ginseng saponin, has several pharmacological activities such as immunosuppressive activity, anti-inflammatory activity, immunological adjuvant, anti-cancer activity and wound-healing activity. Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells. Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx. Ginsenoside Rd inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC50s of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM, and 85.1±9.1 μM, respectively.",947.15,"52705-93-8",{"v":90,"d":"90.00"},95.02,"N/A","N/A","http://selleckchem.com/products/ginsenoside-rd.html","C48H82O18","free base","Panaxoside Rd, Sanchinoside Rd","CC(C)=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C2CCC3(C)C2C(O)CC4C5(C)CCC(OC6OC(CO)C(O)C(O)C6OC7OC(CO)C(O)C(O)C7O)C(C)(C)C5CCC34C",0.548,6,12,13]
["S3935","Nonivamide","b9","L4000-07","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Nonivamide (pelargonic acid vanillylamide, Pseudocapsaicin, Vanillyl-N-nonylamide), present in chili peppers, is commonly manufactured synthetically and used as a food additive to add pungency to seasonings, flavorings, and spice blends. Nonivamide is a agonist, which exhibits 4d-EC50 value of 5.1 mg/L in static toxicity tests.",{"v":293.4,"d":"293.40"},"2444-46-4",{"v":58,"d":"58.00"},197.68,"<1","N/A","https://www.selleckchem.com/products/nonivamide.html","C17H27NO3","free base","pelargonic acid vanillylamide, Pseudocapsaicin, Vanillyl-N-nonylamide","CCCCCCCCC(=O)NCC1=CC(=C(O)C=C1)OC",4.103,2,2,10]
["S3942","Cardamonin","c9","L4000-07","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Cardamonin (Alpinetin chalcone), isolated from the fruits of Alpinia species, is a chalconoid with anti-inflammatory and anti-tumor activity. It has been shown to be a novel antagonist of hTRPA1 cation channel with IC50 of 454 nM while does not interact with TRPV1 nor TRPV4 channel.",270.28,"18956-16-6",{"v":54,"d":"54.00"},199.79,"<1","N/A","http://selleckchem.com/products/cardamonin.html","C16H14O4","free base","Alpinetin chalcone","COC1=CC(=CC(=C1C(=O)C=CC2=CC=CC=C2)O)O",3.201,2,2,4]
["S3944","Valproic acid (VPA)","d9","L4000-07","in 10mM DMSO","Autophagy,HDAC,Mitophagy,Notch,PGC-1α","Epigenetics","Valproic acid (VPA, 2-Propylvaleric Acid, Valproate) is a fatty acid with anticonvulsant properties used in the treatment of epilepsy. It is also a histone deacetylase (HDAC) inhibitor and is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α. Valproic acid activates Notch-1 signaling.",144.21,"99-66-1","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/valproic-acid.html","C8H16O2","free base","2-Propylvaleric Acid, Valproate","CCCC(CCC)C(O)=O",2.749,1,0,5]
["S3945","L-Cycloserine","e9","L4000-07","in 10mM DMSO","Transferase","Metabolism","L-Cycloserine (Levcycloserine, Levcicloserina, Levcycloserinum, (-)-Cycloserine, (S)-Cycloserine) is a potent inhibitor of the sphingolipid pathway via inhibiting 3-ketodihydrosphingosine synthetase. It also inhibits HIV-1 cytopathic effects, replication, and infectivity.",102.09,"339-72-0",{"v":8,"d":"8.00"},78.36,{"v":20,"d":"20.00"},195.91,"http://selleckchem.com/products/l-cycloserine.html","C3H6N2O2","free base","Levcycloserine, Levcicloserina, Levcycloserinum, (-)-Cycloserine, (S)-Cycloserine","NC1CONC1=O",-1.788,2,2,0]
["S3959","(+)-Borneol","f9","L4000-07","in 10mM DMSO","GABA Receptor","Neuronal Signaling","(+)-Borneol is one of enantiomers of borneol which is a valuable medical material, senior aromatic spice, and chemical material and has been used in food and also folk medicine.",154.25,"464-43-7",{"v":30,"d":"30.00"},194.49,"N/A","N/A","http://selleckchem.com/products/positive-rotation-borneol.html","C10H18O","free base","N/A","CC1(C)C2CCC1(C)C(O)C2",1.975,0,1,0]
["S3960","Higenamine hydrochloride","g9","L4000-07","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Higenamine (Norcoclaurine, (+-)-Demethylcoclaurine), also known as Norcoclaurine HCl, is a non-selective β2 adrenoceptor agonist which is a chemical compound naturally occurring in a number of plants.",307.77,"11041-94-4",{"v":61,"d":"61.00"},{"v":198.2,"d":"198.20"},"N/A","N/A","http://selleckchem.com/products/higenamine-hydrochloride.html","C16H17NO3.HCl","hydrochloride","Norcoclaurine HCl, (+-)-Demethylcoclaurine hydrochloride","Cl.OC1=CC=C(CC2NCCC3=CC(=C(O)C=C23)O)C=C1",3.031,0,4,2]
["S3968","Histamine","h9","L4000-07","in 10mM DMSO","Histamine Receptor","Immunology & Inflammation","Histamine, an organic nitrogenous compound, is involved in local immune responses regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. It is a potent H1 and H2 receptor agonist.",111.15,"51-45-6",{"v":22,"d":"22.00"},197.93,"N/A","N/A","http://selleckchem.com/products/histamine.html","C5H9N3","free base","N/A","NCCC1=C[NH]C=N1",-0.714,1,2,2]
["S3969","Veratric acid","a10","L4000-07","in 10mM DMSO","COX,Immunology & Inflammation related,Interleukins,PGES","Immunology & Inflammation","Veratric acid (3,4-Dimethoxybenzoic acid), a simple benzoic acid derived from plants and fruits, has anti-oxidant, anti-inflammation, and blood pressure-lowering effects. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.",182.17,"93-07-2",{"v":36,"d":"36.00"},197.62,"N/A","N/A","http://selleckchem.com/products/veratric-acid.html","C9H10O4","free base","3,4-Dimethoxybenzoic acid","COC1=C(OC)C=C(C=C1)C(O)=O",1.426,3,0,3]
["S3974","(+)-Catechin hydrate","b10","L4000-07","in 10mM DMSO","COX","Immunology & Inflammation","(+)-Catechin hydrate is a plant derived polyphenolic anti-oxidants with phytotoxic properties. (+)-Catechin hydrate is a frequent component of traditional herbal remedies, such as Uncaria rhynchophylla.  (+)-Catechin hydrate inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.",290.27,"225937-10-0",{"v":58,"d":"58.00"},199.81,"N/A","N/A","http://selleckchem.com/products/catechin-hydrate.html","C15H14O6.xH2O","hydrate","N/A","OC1CC2=C(OC1C3=CC(=C(O)C=C3)O)C=C(O)C=C2O",2.021,1,5,1]
["S3977","(-)-Borneol","c10","L4000-07","in 10mM DMSO","GABA Receptor","Neuronal Signaling","(-)-Borneol (L-Borneol), one of enantiomers of borneol, has a camphoraceous and evident woody odor. (-)-Borneol has a highly efficacious positive modulating action at GABA receptor with an EC50 of 237 μM.",154.25,"464-45-9",{"v":30,"d":"30.00"},194.49,"N/A","N/A","http://selleckchem.com/products/l-borneol.html","C10H18O","free base","L-Borneol","CC1(C)C2CCC1(C)C(O)C2",1.975,0,1,0]
["S3988","Theophylline-7-acetic acid","d10","L4000-07","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","Theophylline-7-acetic acid (Acefylline, acetyloxytheophylline, Carboxymethyltheophylline), acting as an adenosine receptor antagonist, is a stimulant drug of the xanthine chemical class.",{"v":238.2,"d":"238.20"},"652-37-9",{"v":47,"d":"47.00"},197.31,"N/A","N/A","http://selleckchem.com/products/theophylline-7-acetic.html","C9H10N4O4","free base","Acefylline, acetyloxytheophylline, Carboxymethyltheophylline","CN1C(=O)N(C)C2=C([N](CC(O)=O)C=N2)C1=O",-0.619,4,0,2]
["S3990","Trans-Anethole","e10","L4000-07","in 10mM DMSO","Fungal","Microbiology","Trans-anethole (4-Propenylanisole) is a phenylpropene derivative found in many essential oils, including anise oil. It has neuromodulatory, anxiolytic, antioxidative, antifungal, anti-inflammatory, and immunomodulatory activities.",{"v":148.2,"d":"148.20"},"4180-23-8",{"v":29,"d":"29.00"},195.68,"N/A","N/A","http://selleckchem.com/products/trans-tnethole.html","C10H12O","free base","4-Propenylanisole","COC1=CC=C(\\C=C\\C)C=C1",2.767,1,0,2]
["S3992","D-(+)-Trehalose dihydrate","f10","L4000-07","in 10mM DMSO","Others","Others","Trehalose is a non-reducing sugar. It is thought to provide plants and animals with the ability to withstanding periods of dehydration.",378.33,"6138-23-4",{"v":75,"d":"75.00"},198.24,"N/A","N/A","http://selleckchem.com/products/d-trehalose-dihyd.html","C12H22O11.2H2O","dihydrate","N/A","O.O.OCC1OC(OC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O",-4.675,3,8,4]
["S3996","Thioctic acid","g10","L4000-07","in 10mM DMSO","Others","Others","Thioctic acid (DL-α-Lipoic acid) is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form., Thioctic acid (DL-α-Lipoic acid)是环状二硫抗氧化剂，可与其还原性二硫酚形式相互转换。",206.33,"1077-28-7",{"v":41,"d":"41.00"},198.71,"N/A","N/A","http://selleckchem.com/products/thioctic-acid.html","C8H14O2S2","free base","DL-α-Lipoic Acid","OC(=O)CCCCC1CCSS1",2.258,1,0,5]
["S4000","Pergolide Mesylate","h10","L4000-07","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Pergolide Mesylate is an antiparkinsonian agent which functions as a dopaminergic agonist.",410.59,"66104-23-2",{"v":10,"d":"10.00"},24.36,{"v":82,"d":"82.00"},199.71,"http://selleckchem.com/products/Pergolide-mesylate.html","C20H30N2O3S2","Mesylate","LY127809","CCCN1CC(CSC)CC2C1CC3=C[NH]C4=C3C2=CC=C4.C[S](O)(=O)=O",3.696,0,1,4]
["S4009","Mirabegron","a11","L4000-07","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Mirabegron (YM 178) is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.",396.51,"223673-61-8",{"v":79,"d":"79.00"},199.24,"<1","N/A","http://selleckchem.com/products/mirabegron-ym178.html","C21H24N4O2S","free base","YM 178","NC1=NC(=CS1)CC(=O)NC2=CC=C(CCNCC(O)C3=CC=CC=C3)C=C2",{"v":2.26,"d":"2.260"},2,4,9]
["S4010","Acebutolol HCl","b11","L4000-07","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Acebutolol is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias.",372.89,"34381-68-5",{"v":75,"d":"75.00"},201.13,{"v":75,"d":"75.00"},201.13,"http://selleckchem.com/products/acebutolol-hcl.html","C18H28N2O4.HCl","Hydrochloride","N/A","Cl.CCCC(=O)NC1=CC(=C(OCC(O)CNC(C)C)C=C1)C(C)=O",1.997,3,3,10]
["S4011","Ampiroxicam","c11","L4000-07","in 10mM DMSO","COX","Neuronal Signaling","Ampiroxicam (CP 65703) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.",447.46,"99464-64-9",{"v":90,"d":"90.00"},201.14,"<1","N/A","http://selleckchem.com/products/ampiroxicam.html","C20H21N3O7S","free base","CP 65703","CCOC(=O)OC(C)OC1=C(N(C)[S](=O)(=O)C2=C1C=CC=C2)C(=O)NC3=NC=CC=C3",1.718,8,1,8]
["S4012","Desloratadine","d11","L4000-07","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Desloratadine (SCH-34117, NSC 675447) is a potent antagonist for  human histamine H1 receptor with IC50 of 51 nM.",310.82,"100643-71-8",{"v":26,"d":"26.00"},83.65,"<1","N/A","http://selleckchem.com/products/desloratadine.html","C19H19ClN2","free base","SCH-34117, NSC 675447","ClC1=CC2=C(C=C1)C(=C3CCNCC3)C4=C(CC2)C=CC=N4",4.213,1,1,0]
["S4014","Hyoscyamine","e11","L4000-07","in 10mM DMSO","AChR","Neuronal Signaling","Hyoscyamine (Daturine) is an AChR inhibitor with IC50 of 7.5 nM.",289.37,"101-31-5",{"v":58,"d":"58.00"},200.44,"<1","N/A","http://selleckchem.com/products/hyoscyamine-daturine.html","C17H23NO3","free base","Daturine","CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",1.721,2,1,5]
["S4021","Tolcapone","f11","L4000-07","in 10mM DMSO","COMT,Histone Methyltransferase,Transferase","Metabolism","Tolcapone (Ro 40-7592) is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with Ki of 30 nM.",273.24,"134308-13-7",{"v":55,"d":"55.00"},201.29,"<1","N/A","http://selleckchem.com/products/tolcapone.html","C14H11NO5","free base","Ro 40-7592","CC1=CC=C(C=C1)C(=O)C2=CC(=C(O)C(=C2)[N+]([O-])=O)O",{"v":3.13,"d":"3.130"},1,2,3]
["S4022","Probenecid","g11","L4000-07","in 10mM DMSO","Taste Receptor,TRP Channel","Transmembrane Transporters","Probenecid (Benemid) is a classical competitive inhibitor of organic anion transport, which is also a TRPV2 agonist and an inhibitor of TAS2R16. Probenecid is also a clinically used broad-spectrum Pannexin1 (Panx1) blocker.",285.36,"57-66-9",{"v":57,"d":"57.00"},199.75,"<1","N/A","http://selleckchem.com/products/probenecid-benemid.html","C13H19NO4S","free base","Benemid","CCCN(CCC)[S](=O)(=O)C1=CC=C(C=C1)C(O)=O",2.321,3,0,7]
["S4023","Procaine HCl","h11","L4000-07","in 10mM DMSO","AChR,NMDAR,Sodium Channel","Transmembrane Transporters","Procaine (Novocaine) is an inhibitor of sodium channel, NMDA receptor and nAChR with IC50 of 60 μM, 0.296 mM and 45.5 μM, which is also an inhibitor of 5-HT3 with KD of 1.7 μM.",272.77,"51-05-8",{"v":55,"d":"55.00"},201.64,{"v":55,"d":"55.00"},201.64,"http://selleckchem.com/products/procaine-novocaine-hcl.html","C13H20N2O2.HCl","HCl","Novocaine HCl","Cl.CCN(CC)CCOC(=O)C1=CC=C(N)C=C1",2.157,2,1,7]
["S4024","Homatropine Methylbromide","a2","L4000-08","in 10mM DMSO","AChR","Neuronal Signaling","Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.",370.28,"80-49-9",{"v":74,"d":"74.00"},199.85,{"v":74,"d":"74.00"},199.85,"http://selleckchem.com/products/homatropine-methylbromide.html","C17H24NO3.Br","quaternary-N bromide salt","N/A","[Br-].C[N+]1(C)C2CCC1CC(C2)OC(=O)C(O)C3=CC=CC=C3",-2.076,2,1,4]
["S4025","Homatropine Bromide","b2","L4000-08","in 10mM DMSO","AChR","Neuronal Signaling","Homatropine Bromide is an muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.",356.25,"51-56-9",{"v":71,"d":"71.00"},{"v":199.3,"d":"199.30"},{"v":71,"d":"71.00"},{"v":199.3,"d":"199.30"},"http://selleckchem.com/products/homatropine-bromide.html","C16H21NO3.HBr","quaternary-N bromide salt","N/A","Br.CN1C2CCC1CC(C2)OC(=O)C(O)C3=CC=CC=C3",2.188,2,1,4]
["S4026","Hydroxyzine 2HCl","c2","L4000-08","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Hydroxyzine is a histamine H1-receptor antagonist, inhibits binding of [3H]pyrilamine/[3H]desloratadine to human histamine H1 receptor with IC50 of 10 nM/19 nM.",447.83,"2192-20-3",{"v":90,"d":"90.00"},200.97,{"v":90,"d":"90.00"},200.97,"http://selleckchem.com/products/hydroxyzine-2hcl.html","C21H27ClN2O2.2HCl","dihydrochloride","N/A","Cl.Cl.OCCOCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3",4.231,1,1,8]
["S4031","Aclidinium Bromide","d2","L4000-08","in 10mM DMSO","AChR","Neuronal Signaling","Aclidinium Bromide (LAS 34273, LAS-W 330) inhibits human muscarinic AChR M1, M2, M3, M4 and M5 with Ki of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM and 0.16 nM, respectively.",564.55,"320345-99-1",{"v":113,"d":"113.00"},200.16,"<1","N/A","http://selleckchem.com/products/aclidinium-bromide.html","C26H30NO4S2.Br","quaternary-N bromide salt","LAS 34273, LAS-W 330","[Br-].OC(C(=O)OC1C[N+]2(CCCOC3=CC=CC=C3)CCC1CC2)(C4=CC=CS4)C5=CC=CS5",0.979,3,0,10]
["S4034","Diphemanil Methylsulfate","e2","L4000-08","in 10mM DMSO","AChR","Neuronal Signaling","Diphemanil Methylsulfate is a quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors (mAchR).",389.51,"62-97-5",{"v":25,"d":"25.00"},64.18,{"v":28,"d":"28.00"},71.89,"http://selleckchem.com/products/diphemanil-methylsulfate.html","C20H24N.CH3O4S","Methylsulfate","N/A","CO[S]([O-])(=O)=O.C[N+]1(C)CC[C](CC1)=[C](C2=CC=CC=C2)C3=CC=CC=C3",0.038,1,0,3]
["S4037","Doxapram HCl","f2","L4000-08","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Doxapram HCl inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.",432.98,"7081-53-0",{"v":87,"d":"87.00"},200.93,{"v":25,"d":"25.00"},57.74,"http://selleckchem.com/products/doxapram-hcl.html","C24H30N2O2.HCl.H2O","HCl","N/A","O.Cl.CCN1CC(CCN2CCOCC2)C(C1=O)(C3=CC=CC=C3)C4=CC=CC=C4",3.218,2,0,6]
["S4038","Dibucaine HCl","g2","L4000-08","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Dibucaine HCl (Cinchocaine) is a local anesthetics.",379.92,"61-12-1",{"v":76,"d":"76.00"},200.04,{"v":76,"d":"76.00"},200.04,"http://selleckchem.com/products/dibucaine-cinchocaine-hcl.html","C20H29N3O2.HCl","hydrochloride","Cinchocaine HCl","Cl.CCCCOC1=CC(=C2C=CC=CC2=N1)C(=O)NCCN(CC)CC",4.294,3,1,10]
["S4039","Methazolamide","h2","L4000-08","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Methazolamide (CL 8490) is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively.",236.27,"554-57-4",{"v":47,"d":"47.00"},198.92,"<1","N/A","http://selleckchem.com/products/methazolamide.html","C5H8N4O3S2","free base","CL 8490","CN1N=C(SC1=NC(C)=O)[S](N)(=O)=O",{"v":0.03,"d":"0.030"},5,1,1]
["S4043","Tetrahydrozoline HCl","a3","L4000-08","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Tetrahydrozoline (Tetryzoline) HCl is an imidazoline derivative with alpha receptor agonist activity.",236.74,"522-48-5",{"v":12,"d":"12.00"},50.69,{"v":47,"d":"47.00"},198.53,"http://selleckchem.com/products/tetrahydrozoline-hcl.html","C13H16N2.HCl","hydrochloride","Tetryzoline HCl","Cl.C1CC(C2=NCCN2)C3=CC=CC=C3C1",2.567,1,1,1]
["S4045","Pheniramine Maleate","b3","L4000-08","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Pheniramine Maleate is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.",356.42,"132-20-7",{"v":71,"d":"71.00"},{"v":199.2,"d":"199.20"},{"v":71,"d":"71.00"},{"v":199.2,"d":"199.20"},"http://selleckchem.com/products/pheniramine-maleate.html","C16H20N2.C4H4O4","Maleate","N/A","CN(C)CCC(C1=CC=CC=C1)C2=NC=CC=C2.OC(=O)\\C=C/C(O)=O",0.036,3,0,7]
["S4049","Valdecoxib","c3","L4000-08","in 10mM DMSO","COX","Neuronal Signaling","Valdecoxib is a potent and selective inhibitor of COX-2 with IC50 of 5 nM.",314.36,"181695-72-7",{"v":63,"d":"63.00"},200.41,"<1","N/A","http://selleckchem.com/products/valdecoxib.html","C16H14N2O3S","free base","N/A","CC1=C(C2=CC=C(C=C2)[S](N)(=O)=O)C(=NO1)C3=CC=CC=C3",{"v":2.6,"d":"2.600"},4,1,3]
["S4051","Nabumetone","d3","L4000-08","in 10mM DMSO","COX","Neuronal Signaling","Nabumetone (BRL-14777) is a non-steroidal anti-inflammatory drug and its active metabolite inhibits the COX.",228.29,"42924-53-8",{"v":46,"d":"46.00"},{"v":201.5,"d":"201.50"},"<1","N/A","http://selleckchem.com/products/nabumetone.html","C15H16O2","free base","BRL-14777","COC1=CC=C2C=C(CCC(C)=O)C=CC2=C1",2.943,2,0,4]
["S4053","Sertraline HCl","e3","L4000-08","in 10mM DMSO","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Sertraline HCl (CP-51974-1) is a 5-HT antagonist with Ki of 13 nM.",342.69,"79559-97-0",{"v":69,"d":"69.00"},201.35,"<1","N/A","http://selleckchem.com/products/sertraline-hcl.html","C17H17Cl2N.HCl","HCl","CP-51974-1 HCl","Cl.CNC1CCC(C2=CC=C(Cl)C(=C2)Cl)C3=C1C=CC=C3",5.378,0,1,2]
["S4058","Ropivacaine HCl","f3","L4000-08","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Ropivacaine HCl (LEA-103) is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.",310.86,"98717-15-8",{"v":62,"d":"62.00"},199.45,{"v":46,"d":"46.00"},147.98,"http://selleckchem.com/products/ropivacaine-hcl.html","C17H26N2O.HCl","HCl","LEA-103 HCl","Cl.CCCN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",4.236,1,1,4]
["S4061","Levobupivacaine HCl","g3","L4000-08","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Levobupivacaine HCl ((S)-(-)-Bupivacaine), the pure S(-)-enantiomer of bupivacaine, is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.",324.89,"27262-48-2",{"v":64,"d":"64.00"},196.99,{"v":64,"d":"64.00"},196.99,"http://selleckchem.com/products/lvobupivacaine-hcl.html","C18H28N2O.HCl","Hydrochloride","(S)-(-)-Bupivacaine HCl","Cl.CCCCN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",4.692,1,1,5]
["S4064","Escitalopram Oxalate","h3","L4000-08","in 10mM DMSO","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Escitalopram Oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.",414.43,"219861-08-2",{"v":83,"d":"83.00"},200.28,{"v":25,"d":"25.00"},60.32,"http://selleckchem.com/products/escitalopram-oxalate.html","C20H21FN2O.C2H2O4","Oxalate","N/A","CN(C)CCCC1(OCC2=CC(=CC=C12)C#N)C3=CC=C(F)C=C3.OC(=O)C(O)=O",0.257,3,0,6]
["S4065","Guanabenz Acetate","a4","L4000-08","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Guanabenz Acetate (WY-8678) is an selective agonist of α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor with pEC50 of 8.25, 7.01 and ~5, respectively.",291.13,"23256-50-0",{"v":58,"d":"58.00"},199.22,"<1","N/A","http://selleckchem.com/products/guanabenz-wy-8678-acetate.html","C8H8Cl2N4.C2H4O2","Acetate","WY-8678 Acetate","CC(O)=O.NC(=N)N/N=C/C1=C(Cl)C=CC=C1Cl",1.987,2,2,3]
["S4072","Decamethonium Bromide","b4","L4000-08","in 10mM DMSO","AChR","Neuronal Signaling","Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent.",418.29,"541-22-0",{"v":34,"d":"34.00"},81.28,{"v":84,"d":"84.00"},200.82,"http://selleckchem.com/products/decamethonium-bromide.html","C16H38N2.2Br","Bromide","N/A","[Br-].[Br-].C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C",-3.707,0,0,11]
["S4076","Propranolol HCl","c4","L4000-08","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Propranolol HCl (AY-64043, ICI-45520, NCS-91523) is a competitive non-selective beta-adrenergic receptors inhibitor.",{"v":295.8,"d":"295.80"},"318-98-9",{"v":59,"d":"59.00"},199.46,{"v":6,"d":"6.00"},20.28,"http://selleckchem.com/products/propranolol-hcl.html","C16H21NO2.HCl","Hydrochloride","AY-64043, ICI-45520, NCS-91523","Cl.CC(C)NCC(O)COC1=CC=CC2=CC=CC=C12",2.922,1,2,6]
["S4078","Mefenamic Acid","d4","L4000-08","in 10mM DMSO","COX","Neuronal Signaling","Mefenamic Acid (CI 473, CN-35355) is a competitive inhibitor of COX-1 and COX-2.",241.29,"61-68-7",{"v":48,"d":"48.00"},198.93,"<1","N/A","http://selleckchem.com/products/mefenamic-acid.html","C15H15NO2","free base","CI 473, CN-35355","CC1=C(C)C(=CC=C1)NC2=CC=CC=C2C(O)=O",3.982,1,1,3]
["S4079","Ticagrelor","e4","L4000-08","in 10mM DMSO","P2 Receptor","Neuronal Signaling","Ticagrelor (AZD 6140, AR-C 126532XX) is the first reversibly binding oral P2Y12 receptor antagonist with Ki of 2 nM.",522.57,"274693-27-5",{"v":100,"d":"100.00"},191.36,"<1","N/A","http://selleckchem.com/products/ticagrelor.html","C23H28F2N6O4S","free base","AZD 6140, AR-C 126532XX","CCCSC1=NC2=C(N=N[N]2C3CC(OCCO)C(O)C3O)C(=N1)NC4CC4C5=CC(=C(F)C=C5)F",2.843,5,4,10]
["S4080","Triamterene","f4","L4000-08","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Triamterene (SKF8542) blocks epithelial Na+ channel (ENaC) in a voltage-dependent manner with IC50 of 4.5 μM.",253.26,"396-01-0",{"v":20,"d":"20.00"},78.97,"<1","N/A","http://selleckchem.com/products/triamterene.html","C12H11N7","free base","SKF8542","NC1=NC2=C(N=C(C3=CC=CC=C3)C(=N2)N)C(=N1)N",1.017,4,3,1]
["S4084","Lomerizine 2HCl","g4","L4000-08","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Lomerizine dihydrochloride (KB-2796) is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine.",541.46,"101477-54-7",{"v":100,"d":"100.00"},184.69,"<1","N/A","http://selleckchem.com/products/lomerizine-hcl.html","C27H30F2N2O3.2HCl","Dihydrochloride","KB-2796","Cl.Cl.COC1=C(OC)C(=C(CN2CCN(CC2)C(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)C=C1)OC",6.182,3,0,8]
["S4085","Levobetaxolol HCl","h4","L4000-08","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Levobetaxolol (AL 1577A,(S)-Betaxolol hydrochloride) exhibits a higher affinity at cloned human β1 and β2 receptors with Ki value of 0.76 nM and 32.6 nM, respectively.",343.89,"116209-55-3",{"v":69,"d":"69.00"},200.65,{"v":69,"d":"69.00"},200.65,"http://selleckchem.com/products/levobetaxolol-hcl.html","C18H29NO3.HCl","Hydrochloride","AL 1577A,(S)-Betaxolol hydrochloride","Cl.CC(C)NCC(O)COC1=CC=C(CCOCC2CC2)C=C1",2.959,2,2,11]
["S4086","Loxapine Succinate","a5","L4000-08","in 10mM DMSO","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Loxapine Succinate(NSC 759578) is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent.",{"v":445.9,"d":"445.90"},"27833-64-3",{"v":89,"d":"89.00"},{"v":199.6,"d":"199.60"},"<1","N/A","http://selleckchem.com/products/loxapine-succinate.html","C18H18ClN3O.C4H6O4","Succinate","NSC 759578","CN1CCN(CC1)C2=NC3=C(OC4=C2C=C(Cl)C=C4)C=CC=C3.OC(=O)CCC(O)=O",0.039,4,0,4]
["S4088","Flumethasone","b5","L4000-08","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Flumethasone (RS-2177, NSC-54702,Flumetasone) is a glucocorticoid receptor agonist, this complex binds to the nucleus causing a variety of genetic activation and repressions.",410.45,"2135-17-3",{"v":82,"d":"82.00"},199.78,"<1","N/A","http://selleckchem.com/products/flumethasone.html","C22H28F2O5","free base","RS-2177, NSC-54702,Flumetasone","CC1CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO",1.546,2,2,2]
["S4090","Fenspiride HCl","c5","L4000-08","in 10mM DMSO","PDE","Metabolism","Fenspiride(Decaspiride) is a bronchodilator with anti-inflammatory properties, inhibiting phosphodiesterase 4 and phosphodiesterase 3 activities with logIC50 values of 4.16 and 3.44, respectively, in human isolated bronchi.",296.79,"5053-08-7",{"v":9,"d":"9.00"},30.32,{"v":59,"d":"59.00"},198.79,"http://selleckchem.com/products/Fenspiride-hcl.html","C15H20N2O2.HCl","Hydrochloride","Decaspiride","Cl.O=C1NCC2(CCN(CCC3=CC=CC=C3)CC2)O1",2.089,2,1,3]
["S4091","Ifenprodil Tartrate","d5","L4000-08","in 10mM DMSO","NMDAR","Neuronal Signaling","Ifenprodil is an atypical noncompetitive antagonist at the NMDA receptor, it interacts with high affinity at a homogeneous population of NMDA receptors in neonatal rat forebrain with IC50 of 0.3 μM.",800.98,"23210-58-4",{"v":95,"d":"95.00"},{"v":118.6,"d":"118.60"},{"v":9,"d":"9.00"},11.24,"http://selleckchem.com/products/ifenprodil-tartrate.html","2(C21H27NO2).C4H6O6","Tartrate","N/A","CC(C(O)C1=CC=C(O)C=C1)N2CCC(CC2)CC3=CC=CC=C3.CC(C(O)C4=CC=C(O)C=C4)N5CCC(CC5)CC6=CC=CC=C6.OC(C(O)C(O)=O)C(O)=O",0.638,2,6,13]
["S4092","Pramoxine HCl","e5","L4000-08","in 10mM DMSO","Others","Others","Pramoxine(Pramocaine hydrochloride) is a topical local anesthetic that has been shown to have antipruritic properties.",329.86,"637-58-1",{"v":66,"d":"66.00"},200.08,{"v":66,"d":"66.00"},200.08,"http://selleckchem.com/products/pramoxine-hcl.html","C17H27NO3.HCl","Hydrochloride","Pramocaine hydrochloride","Cl.CCCCOC1=CC=C(OCCCN2CCOCC2)C=C1",3.396,3,0,9]
["S4096","Droperidol","f5","L4000-08","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Droperidol (NSC 169874,Dehydrobenzperidol) is a potent antagonist of dopamine subtype 2 receptors in the limbic system.",379.43,"548-73-2",{"v":76,"d":"76.00"},{"v":200.3,"d":"200.30"},"<1","N/A","http://selleckchem.com/products/droperidol.html","C22H22FN3O2","free base","NSC 169874,Dehydrobenzperidol","FC1=CC=C(C=C1)C(=O)CCCN2CCC(=CC2)N3C(=O)NC4=C3C=CC=C4",3.049,2,1,6]
["S4100","Esmolol HCl","g5","L4000-08","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Esmolol (ASL8052) is a cardioselective b-blocker, used to control rapid heartbeats or abnormal heart rhythms.",331.83,"81161-17-3",{"v":66,"d":"66.00"},{"v":198.9,"d":"198.90"},{"v":66,"d":"66.00"},{"v":198.9,"d":"198.90"},"http://selleckchem.com/products/esmolol-hcl.html","C16H25NO4.HCl","Hydrochloride","ASL8052","Cl.COC(=O)CCC1=CC=C(OCC(O)CNC(C)C)C=C1",{"v":2.36,"d":"2.360"},3,2,10]
["S4102","Eprosartan Mesylate","h5","L4000-08","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Eprosartan(SKF-108566J) is a nonpeptide angiotensin II receptor antagonist, [3H]-eprosartan binds to the AT1 receptor with KD of 0.83 nM in rat vascular smooth muscle cells.",520.62,"144143-96-4",{"v":104,"d":"104.00"},199.76,"<1","N/A","http://selleckchem.com/products/eprosartan-mesylate.html","C23H24N2O4S.CH4O3S","Mesylate","SKF-108566J","CCCCC1=NC=C(\\C=C(CC2=CC=CS2)\\C(O)=O)[N]1CC3=CC=C(C=C3)C(O)=O.C[S](O)(=O)=O",4.418,3,0,10]
["S4112","Desvenlafaxine Succinate hydrate","a6","L4000-08","in 10mM DMSO","Adrenergic Receptor,Serotonin Transporter","Neuronal Signaling","Desvenlafaxine Succinate hydrate (WY 45233) is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively.",399.48,"386750-22-7",{"v":80,"d":"80.00"},191.22,"<1","N/A","http://selleckchem.com/products/desvenlafaxine-succinate.html","C16H25NO2.C4H6O4.H2O","Succinate hydrate","WY 45233  Succinate","O.CN(C)CC(C1=CC=C(O)C=C1)C2(O)CCCCC2.OC(=O)CCC(O)=O",-0.598,2,1,7]
["S4113","Desvenlafaxine","b6","L4000-08","in 10mM DMSO","Adrenergic Receptor,Serotonin Transporter","Neuronal Signaling","Desvenlafaxine (WY 45233 Succinate) is a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with Ki of 40.2 nM and 558.4 nM, respectively.",263.38,"93413-62-8",{"v":37,"d":"37.00"},140.48,"<1","N/A","http://selleckchem.com/products/desvenlafaxine.html","C16H25NO2","Free Base","WY 45233  Succinate","CN(C)CC(C1=CC=C(O)C=C1)C2(O)CCCCC2",2.796,0,1,4]
["S4116","Isovaleramide","c6","L4000-08","in 10mM DMSO","Dehydrogenase","Metabolism","Isovaleramide(3-Methylbutanamide) is an anticonvulsant molecule isolated from Valeriana pavonii, it inhibits the liver alcohol dehydrogenases.",101.15,"541-46-8",{"v":20,"d":"20.00"},197.73,"<1","N/A","http://selleckchem.com/products/isovaleramide.html","C5H11NO","free base","3-Methylbutanamide","CC(C)CC(N)=O",0.542,1,1,2]
["S4118","Histamine 2HCl","d6","L4000-08","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Histamine(Ceplene) is an organic nitrogen compound, acts on target cells in mammalian brain via stimulation of Histamine 1/2.",184.07,"56-92-8",{"v":3,"d":"3.00"},{"v":16.3,"d":"16.30"},{"v":37,"d":"37.00"},201.01,"http://selleckchem.com/products/histamine-2hcl.html","C5H9N3.2HCl","Dihydrochloride","Ceplene","Cl.Cl.NCCC1=C[NH]C=N1",{"v":0.05,"d":"0.050"},1,2,2]
["S4123","Timolol Maleate","e6","L4000-08","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Timolol Maleate (MK-950,(S)-Timolol Maleate) is a non-selective, beta-adrenergic receptor antagonist for β1/β2 with Ki of 1.97 nM/2.0 nM.",432.49,"26921-17-5",{"v":86,"d":"86.00"},198.85,"<1","N/A","http://selleckchem.com/products/timolol-maleate.html","C13H24N4O3S.C4H4O4","Maleate","MK-950,(S)-Timolol Maleate","CC(C)(C)NCC(O)COC1=NSN=C1N2CCOCC2.OC(=O)\\C=C/C(O)=O",-1.539,6,2,9]
["S4124","Tolazoline HCl","f6","L4000-08","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Tolazoline(Imidaline hydrochloride,NSC35110 hydrochloride) is a non-selective competitive α-adrenergic receptor antagonist.",196.68,"59-97-2",{"v":39,"d":"39.00"},198.29,{"v":39,"d":"39.00"},198.29,"http://selleckchem.com/products/tolazoline-hcl.html","C10H12N2.HCl","Hydrochloride","Imidaline hydrochloride,NSC35110 hydrochloride","Cl.C1CN=C(CC2=CC=CC=C2)N1",1.533,1,1,2]
["S4125","Sodium Phenylbutyrate","g6","L4000-08","in 10mM DMSO","HDAC","DNA Damage/DNA Repair","Sodium phenylbutyrate (4-PBA, 4-Phenylbutyric acid, NaPB) is a salt of 4-phenylbutyrate (4-PBA) or 4-phenylbutyric acid.Sodium phenylbutyrate is a histone deacetylase inhibitor, used to treat urea cycle disorders.",187.19,"1716-12-7",{"v":8,"d":"8.00"},42.97,{"v":30,"d":"30.00"},161.13,"http://selleckchem.com/products/sodium-phenylbutyrate.html","C10H11O2.Na","Sodium Salt","4-PBA, 4-Phenylbutyric acid, NaPB","[Na]OC(=O)CCCC1=CC=CC=C1",2.497,2,0,5]
["S4131","Levodropropizine","h6","L4000-08","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Levodropropizine((S)-(-)-Dropropizine,DF-526) possess anti-allergic and inhibits histamine receptor, reduces cough by interfering with stimulus activation of peripheral endings of sensory nerves and by modulation of neuropeptides involved in the cough reflex.",236.31,"99291-25-5",{"v":47,"d":"47.00"},198.89,{"v":15,"d":"15.00"},63.48,"http://selleckchem.com/products/levodropropizine.html","C13H20N2O2","free base","(S)-(-)-Dropropizine,DF-526","OCC(O)CN1CCN(CC1)C2=CC=CC=C2",0.899,0,2,4]
["S4135","Clorprenaline HCl","a7","L4000-08","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Clorprenaline HCl (NSC 334693) is a β2-receptor agonist, it has a significant expansion of the bronchial effect.",250.16,"6933-90-0",{"v":50,"d":"50.00"},199.87,{"v":50,"d":"50.00"},199.87,"http://selleckchem.com/products/clorprenaline-hcl.html","C11H16ClNO.HCl","Hydrochloride","NSC 334693","Cl.CC(C)NCC(O)C1=CC=CC=C1Cl",2.629,0,2,4]
["S4136","Carprofen","b7","L4000-08","in 10mM DMSO","COX","Neuronal Signaling","Carprofen inhibits canine COX2 with IC50 of 30 nM.",273.71,"53716-49-7",{"v":55,"d":"55.00"},200.94,"<1","N/A","http://selleckchem.com/products/carprofen.html","C15H12ClNO2","free base","N/A","CC(C(O)=O)C1=CC2=C(C=C1)C3=C([NH]2)C=CC(=C3)Cl",4.114,1,1,2]
["S4139","Cyclizine 2HCl","c7","L4000-08","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Cyclizine 2HCl is a piperazine derivative with Histamine H1 receptor antagonist activity.",{"v":339.3,"d":"339.30"},"5897-18-7",{"v":7,"d":"7.00"},20.63,{"v":68,"d":"68.00"},200.41,"http://selleckchem.com/products/cyclizine-2hcl.html","C18H22N2.2HCl","Hydrochloride","N/A","Cl.Cl.CN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3",4.237,0,0,3]
["S4143","Pentoxyverine Citrate","d7","L4000-08","in 10mM DMSO","AChR","Neuronal Signaling","Pentoxyverine Citrate (Carbetapentane) is an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold.",525.59,"23142-01-0",{"v":100,"d":"100.00"},190.26,{"v":100,"d":"100.00"},190.26,"http://selleckchem.com/products/pentoxyverine-carbetapentane-citrate.html","C20H31NO3.C6H8O7","Citrate","Carbetapentane Citrate","CC(C)N(CCC(C(N)=O)(C1=CC=CC=C1)C2=CC=CC=N2)C(C)C.O[P](O)(O)=O",2.949,2,1,8]
["S4149","Amfenac Sodium Monohydrate","e7","L4000-08","in 10mM DMSO","COX","Neuronal Signaling","Amfenac Sodium monohydrate is a non-steroidal analgesic anti-inflammatory drug with acetic acid moiety. The IC50 values for COX1 and COX2 is 250 nM and 150 nM, respectively.",295.27,"61618-27-7",{"v":59,"d":"59.00"},199.82,{"v":59,"d":"59.00"},199.82,"http://selleckchem.com/products/amfenac-sodium-monohydrate.html","C15H12NO3.H2O.Na","free base","N/A","O.[Na+].NC1=C(C=CC=C1CC([O-])=O)C(=O)C2=CC=CC=C2",{"v":0.47,"d":"0.470"},1,1,4]
["S4151","Penfluridol","f7","L4000-08","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Penfluridol (TLP-607,R-16341) is a highly potent, first generation diphenylbutylpiperidine antipsychotic.",523.97,"26864-56-2",{"v":100,"d":"100.00"},190.85,"<1","N/A","http://selleckchem.com/products/penfluridol.html","C28H27ClF5NO","free base","TLP-607,R-16341","OC1(CCN(CCCC(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3)CC1)C4=CC(=C(Cl)C=C4)C(F)(F)F",7.311,0,0,8]
["S4155","Chlorzoxazone","g7","L4000-08","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Chlorzoxazone(Chlorzoxazon,Paraflex) is a muscle-relaxing drug,and a probe for human liver cytochrome P-450IIE1.",169.57,"95-25-0",{"v":34,"d":"34.00"},200.51,"<1","N/A","http://selleckchem.com/products/chlorzoxazone.html","C7H4ClNO2","free base","Chlorzoxazon,Paraflex","ClC1=CC2=C(OC(=O)N2)C=C1",2.004,2,1,0]
["S4162","Benzethonium Chloride","h7","L4000-08","in 10mM DMSO","AChR","Neuronal Signaling","Benzethonium chloride is a potent inhibitor of nAChRs, it inhibits α4β2 nAChRs and α7 nAChRs with IC50 of 49 nM and 122 nM, respectively.",448.08,"121-54-0",{"v":90,"d":"90.00"},200.86,{"v":90,"d":"90.00"},200.86,"http://selleckchem.com/products/benzethonium-chloride.html","C27H42NO2.Cl","Chloride","N/A","[Cl-].CC(C)(C)CC(C)(C)C1=CC=C(OCCOCC[N+](C)(C)CC2=CC=CC=C2)C=C1",2.147,2,0,12]
["S4164","Doxofylline","a8","L4000-08","in 10mM DMSO","PDE","Metabolism","Doxofylline (Doxophylline) is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma.",266.25,"69975-86-6",{"v":53,"d":"53.00"},199.06,{"v":24,"d":"24.00"},90.14,"http://selleckchem.com/products/doxofylline.html","C11H14N4O4","free base","Doxophylline","CN1C(=O)N(C)C2=C([N](CC3OCCO3)C=N2)C1=O",-0.344,5,0,2]
["S4170","Coumarin","b8","L4000-08","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Coumarin is a secondary phytochemical with hepatotoxic and carcinogenic properties.",146.14,"91-64-5",{"v":29,"d":"29.00"},198.44,"<1","N/A","http://selleckchem.com/products/coumarin.html","C9H6O2","free base","N/A","O=C1OC2=C(C=CC=C2)C=C1",1.899,2,0,0]
["S4171","Choline Chloride","c8","L4000-08","in 10mM DMSO","AChR","Neuronal Signaling","Choline chloride(Hepacholine) is a quaternary ammonium salt used as an additive for animal feed. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.",139.62,"67-48-1",{"v":28,"d":"28.00"},200.54,{"v":28,"d":"28.00"},200.54,"http://selleckchem.com/products/choline-chloride.html","C5H14NO.Cl","Chloride","Hepacholine","[Cl-].C[N+](C)(C)CCO",-4.248,0,1,2]
["S4176","Trometamol","d8","L4000-08","in 10mM DMSO","COX","Neuronal Signaling","Trometamol(Tromethamine) is a proton acceptor used to treat acidemia.",121.14,"77-86-1",{"v":2,"d":"2.00"},16.51,{"v":24,"d":"24.00"},198.12,"http://selleckchem.com/products/trometamol.html","C4H11NO3","free base","Tromethamine","NC(CO)(CO)CO",-2.381,0,4,3]
["S4181","Nicardipine HCl","e8","L4000-08","in 10mM DMSO","ADC Cytotoxin,Calcium Channel","Transmembrane Transporters","Nicardipine HCl (RS-69216,YC-93) is a dihydropyridine calcium-channel blocking agent used for the treatment of vascular disorders.",515.99,"54527-84-3",{"v":100,"d":"100.00"},{"v":193.8,"d":"193.80"},"<1","N/A","http://selleckchem.com/products/nicardipine-hcl.html","C26H29N3O6.HCl","Hydrochloride","RS-69216,YC-93","Cl.COC(=O)C1=C(C)NC(=C(C1C2=CC(=CC=C2)[N+]([O-])=O)C(=O)OCCN(C)CC3=CC=CC=C3)C",{"v":3.87,"d":"3.870"},4,1,11]
["S4188","Sasapyrine","f8","L4000-08","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Sasapyrine (Salsalate, NSC-49171) is a nonsteroidal oral anti-inflammatory agent.",258.23,"552-94-3",{"v":52,"d":"52.00"},201.37,"<1","N/A","http://selleckchem.com/products/sasapyrine.html","C14H10O5","free base","NSC-49171,Salsalate","OC(=O)C1=CC=CC=C1OC(=O)C2=CC=CC=C2O",2.649,3,1,4]
["S4197","Bemegride","g8","L4000-08","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Bemegride(Bemegrid,3-Ethyl-3-methylglutarimide) is a central nervous system stimulant and antidote for barbiturate poisoning.",155.19,"64-65-3",{"v":31,"d":"31.00"},199.76,"<1","N/A","http://selleckchem.com/products/bemegride.html","C8H13NO2","free base","Bemegrid,3-Ethyl-3-methylglutarimide","CCC1(C)CC(=O)NC(=O)C1",0.578,2,1,1]
["S4200","Tolperisone HCl","h8","L4000-08","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Tolperisone HCl is an ion channel blocker and centrally-acting muscle relaxant.",281.82,"3644-61-9",{"v":56,"d":"56.00"},198.71,{"v":56,"d":"56.00"},198.71,"http://selleckchem.com/products/tolperisone-hcl.html","C16H23NO.HCl","Hydrochloride","N/A","Cl.CC(CN1CCCCC1)C(=O)C2=CC=C(C)C=C2",4.072,1,0,4]
["S4202","Verapamil (CP-16533-1) HCl","a9","L4000-08","in 10mM DMSO","Calcium Channel,P450 (e.g. CYP17),P-gp","Transmembrane Transporters","Verapamil HCl (CP-16533-1,(±)-Verapamil hydrochloride) is an L-type calcium channel blocker that is a class IV anti-arrhythmia agent. Verapamil inhibits both permeability-glycoprotein (P-gp) and CYP3A4.",491.06,"152-11-4",{"v":98,"d":"98.00"},199.57,{"v":50,"d":"50.00"},101.82,"http://selleckchem.com/products/verapami-hcl.html","C27H38N2O4.HCl","Hydrochloride","(±)-Verapamil hydrochloride","Cl.COC1=CC=C(CCN(C)CCCC(C#N)(C(C)C)C2=CC=C(OC)C(=C2)OC)C=C1OC",5.916,4,0,13]
["S4210","Benzocaine","b9","L4000-08","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Benzocaine(ethyl 4-aminobenzoate) is the ethyl ester of p-aminobenzoic acid (PABA), it is a local anesthetic commonly used as a topical pain reliever or in cough drops.",165.19,"94-09-7",{"v":33,"d":"33.00"},199.77,"<1","N/A","http://selleckchem.com/products/benzocaine.html","C9H11NO2","Free Base","ethyl 4-aminobenzoate","CCOC(=O)C1=CC=C(N)C=C1",1.287,2,1,3]
["S4219","Azaperone","c9","L4000-08","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Azaperone (NSC 170976) crosses the blood-brain barrier and binds to both DI and D2 receptors, being an antagonist of Dopamine receptors with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.",{"v":327.4,"d":"327.40"},"1649-18-9",{"v":65,"d":"65.00"},198.53,"<1","N/A","http://selleckchem.com/products/azaperone.html","C19H22FN3O","free base","NSC 170976","FC1=CC=C(C=C1)C(=O)CCCN2CCN(CC2)C3=CC=CC=N3",3.368,2,0,6]
["S4225","Mexiletine HCl","d9","L4000-08","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Mexiletine HCl (KO1173,Mexitil) belongs to Class IB anti-arrhythmic group of medicines, inhibits sodium channels to reduce the inward sodium current.",215.72,"5370-01-4",{"v":43,"d":"43.00"},199.33,{"v":43,"d":"43.00"},199.33,"http://selleckchem.com/products/mexiletine-hcl.html","C11H17NO.HCl","Hydrochloride","KO1173,Mexitil","Cl.CC(N)COC1=C(C)C=CC=C1C",2.716,1,1,3]
["S4228","Fluorometholone Acetate","e9","L4000-08","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Fluorometholone Acetate (NSC 47438,Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.",{"v":418.5,"d":"418.50"},"3801-06-7",{"v":83,"d":"83.00"},198.33,"<1","N/A","http://selleckchem.com/products/fluorometholone-acetate.html","C24H31FO5","free base","NSC 47438,Oxylone acetate","CC1CC2C3CCC(OC(C)=O)(C(C)=O)C3(C)CC(O)C2(F)C4(C)C=CC(=O)C=C14",2.691,4,1,3]
["S4229","Oxybuprocaine HCl","f9","L4000-08","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Oxybuprocaine HCl(oxybuprocaine hydrochloride) is a local anesthetic, which is used especially in ophthalmology and otolaryngology.  Oxybuprocaine binds to sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions",344.88,"5987-82-6",{"v":69,"d":"69.00"},200.07,{"v":69,"d":"69.00"},200.07,"http://selleckchem.com/products/oxybuprocaine-hcl.html","C17H28N2O3.HCl","Hydrochloride","oxybuprocaine hydrochloride","Cl.CCCCOC1=CC(=CC=C1N)C(=O)OCCN(CC)CC",3.469,3,1,11]
["S4230","Oxaprozin","g9","L4000-08","in 10mM DMSO","COX","Metabolism","Oxaprozin (WY-21743,nsc 310839) is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID) used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis.",293.32,"21256-18-8",{"v":59,"d":"59.00"},201.15,"<1","N/A","http://selleckchem.com/products/oxaprozin.html","C18H15NO3","free base","WY-21743,nsc 310839","OC(=O)CCC1=NC(=C(O1)C2=CC=CC=C2)C3=CC=CC=C3",{"v":3.59,"d":"3.590"},3,0,5]
["S4231","Pilocarpine HCl","h9","L4000-08","in 10mM DMSO","AChR","Neuronal Signaling","Pilocarpine HCl (NSC 5746) is a nonselective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy.",244.72,"54-71-7",{"v":48,"d":"48.00"},196.14,{"v":48,"d":"48.00"},196.14,"http://selleckchem.com/products/pilocarpine-hcl.html","C11H16N2O2.HCl","Hydrochloride","NSC 5746 HCl","Cl.CCC1C(COC1=O)CC2=CN=C[N]2C",1.347,3,0,3]
["S4233","Zoxazolamine","a10","L4000-08","in 10mM DMSO","Others","Others","Zoxazolamine (NSC 24995, Contrazole) is a centrally acting myorelaxant, which is formerly used as an antispasmodic and uricosuric.",168.58,"61-80-3",{"v":34,"d":"34.00"},201.68,"<1","N/A","http://selleckchem.com/products/zoxazolamine.html","C7H5ClN2O","free base","NSC 24995, Contrazole","NC1=NC2=C(O1)C=CC(=C2)Cl",1.815,2,1,0]
["S4235","Phenazopyridine HCl","b10","L4000-08","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Phenazopyridine HCl is a local analgesic that has been used in urinary tract disorders. It is an inhibitor of sodium channel protein type 1 subunit alpha.",{"v":249.7,"d":"249.70"},"136-40-3",{"v":50,"d":"50.00"},200.24,"<1","N/A","http://selleckchem.com/products/phenazopyridine-hcl.html","C11H11N5.HCl","Hydrochloride","N/A","Cl.NC1=NC(=C(C=C1)N=NC2=CC=CC=C2)N",3.015,3,2,2]
["S4240","Doxylamine Succinate","c10","L4000-08","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Doxylamine succinate competitively inhibits histamine at H1 receptors with substantial sedative and anticholinergic effects.",388.46,"562-10-7",{"v":78,"d":"78.00"},200.79,{"v":78,"d":"78.00"},200.79,"http://selleckchem.com/products/doxylamine-succinate.html","C17H22N2O.C4H6O4","Succinate","N/A","CN(C)CCOC(C)(C1=CC=CC=C1)C2=CC=CC=N2.OC(=O)CCC(O)=O",-0.527,4,0,9]
["S4243","Deoxycorticosterone acetate","d10","L4000-08","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Deoxycorticosterone acetate (11-Deoxycorticosterone, DOC, Cortexone) is a steroid hormone used for intramuscular injection for replacement therapy of the adrenocortical steroid.",{"v":372.5,"d":"372.50"},"56-47-3",{"v":11,"d":"11.00"},29.53,"<1","N/A","http://selleckchem.com/products/deoxycorticosterone-acetate.html","C23H32O4","free base","11-Deoxycorticosterone acetate, DOC acetate, Cortexone acetate","CC(=O)OCC(=O)C1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C",3.567,4,0,4]
["S4244","Serotonin HCl","e10","L4000-08","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Serotonin HCl (5-HT) is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist.",212.68,"153-98-0",{"v":42,"d":"42.00"},197.48,{"v":42,"d":"42.00"},197.48,"http://selleckchem.com/products/serotonin-hcl.html","C10H12N2O.HCl","Hydrochloride","5-HT HCl","Cl.NCCC1=C[NH]C2=CC=C(O)C=C12",{"v":1.69,"d":"1.690"},0,3,2]
["S4246","Tranylcypromine (2-PCPA) HCl","f10","L4000-08","in 10mM DMSO","MAO","Metabolism","Tranylcypromine HCl (2-PCPA, SKF-385, Parnate) is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively.",169.65,"1986-47-6",{"v":33,"d":"33.00"},194.52,{"v":33,"d":"33.00"},194.52,"http://selleckchem.com/products/tranylcypromine-2-pcpa-hcl.html","C9H12ClN","Hydrochloride","SKF-385 HCl, Parnate,2-PCPA","Cl.NC1CC1C2=CC=CC=C2",2.309,0,1,1]
["S4247","Prucalopride Succinate","g10","L4000-08","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Prucalopride(R-108512) is a selective, high affinity 5-HT4 receptor agonist. The Ki values of prucalopride for human 5-HT(4a) and 5-HT(4b) receptor are 2.5 nM and 8 nM, respectively.",485.96,"179474-85-2",{"v":97,"d":"97.00"},{"v":199.6,"d":"199.60"},{"v":97,"d":"97.00"},{"v":199.6,"d":"199.60"},"http://selleckchem.com/products/prucalopride-succinat.html","C18H26ClN3O3.C4H6O4","Succinat","R-108512","COCCCN1CCC(CC1)NC(=O)C2=C3OCCC3=C(N)C(=C2)Cl.OC(=O)CCC(O)=O",-2.338,5,2,9]
["S4248","Bromfenac Sodium","h10","L4000-08","in 10mM DMSO","COX","Neuronal Signaling","Bromfenac Sodium (AHR 10282R,Bromsite,Bromday,Prolensa,Xibrom) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.",356.15,"91714-93-1",{"v":71,"d":"71.00"},199.35,{"v":71,"d":"71.00"},199.35,"http://selleckchem.com/products/bromfenac-sodium.html","C15H11BrNO3.Na","Sodium Salt","AHR 10282R,Bromsite,Bromday,Prolensa,Xibrom","[Na+].NC1=C(C=CC=C1CC([O-])=O)C(=O)C2=CC=C(Br)C=C2",1.426,1,1,4]
["S4249","Flopropione","a11","L4000-08","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Flopropione is a spasmolytic or antispasmodic agent, and acts as a 5-HT1A receptor antagonist.",182.17,"2295-58-1",{"v":36,"d":"36.00"},197.62,"<1","N/A","http://selleckchem.com/products/flopropione.html","C9H10O4","free base","N/A","CCC(=O)C1=C(O)C=C(O)C=C1O",{"v":1.51,"d":"1.510"},1,3,2]
["S4251","Phenothiazine","b11","L4000-08","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Phenothiazine (ENT 38) is a dopamine-2 (D2) receptor antagonist therefore decreases the effect of dopamine in the brain.",199.27,"92-84-2",{"v":40,"d":"40.00"},200.73,"<1","N/A","http://selleckchem.com/products/phenothiazine.html","C12H9NS","free base","ENT 38","N1C2=C(SC3=CC=CC=C13)C=CC=C2",3.668,0,1,0]
["S4253","Epinastine HCl","c11","L4000-08","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Epinastine (WAL-801CL) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.",285.77,"108929-04-0",{"v":57,"d":"57.00"},199.46,{"v":57,"d":"57.00"},199.46,"http://selleckchem.com/products/epinastine-hcl.html","C16H15N3.HCl","Hydrochloride","WAL-801CL HCl","Cl.NC1=NCC2N1C3=CC=CC=C3CC4=CC=CC=C24",3.164,1,1,0]
["S4256","Buspirone HCl","d11","L4000-08","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Buspirone(Buspirone hydrochloride) is a serotonergic (5HT(1A) receptor agonist) anxiolytic drug with some D(2) dopaminergic effect, used for anxiety disorders.",421.96,"33386-08-2",{"v":84,"d":"84.00"},199.07,{"v":84,"d":"84.00"},199.07,"http://selleckchem.com/products/buspirone-hcl.html","C21H31N5O2.HCl","Hydrochloride","Buspirone hydrochloride","Cl.O=C1CC2(CCCC2)CC(=O)N1CCCCN3CCN(CC3)C4=NC=CC=N4",2.403,4,0,6]
["S4257","Alizapride HCl","e11","L4000-08","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Alizapride HCl(Alizapride hydrochloride) is a dopamine receptor antagonist used for the theropy of nausea and vomiting.",351.83,"59338-87-3",{"v":42,"d":"42.00"},119.38,{"v":70,"d":"70.00"},198.96,"http://selleckchem.com/products/alizapride-hcl.html","C16H21N5O2.HCl","hydrochloride","Alizapride hydrochloride","Cl.COC1=CC2=C(C=C1C(=O)NCC3CCCN3CC=C)N=N[NH]2",2.253,4,2,6]
["S4259","Vilazodone HCl","f11","L4000-08","in 10mM DMSO","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Vilazodone HCl(EMD68843,SB659746A) is a selective serotonin reuptake inhibitor (SSRI) and  a partial agonist of 5-HT1A receptors, used for the treatment of major depressive disorder.",477.99,"163521-08-2",{"v":96,"d":"96.00"},200.84,"<1","N/A","http://selleckchem.com/products/vilazodone-hcl.html","C26H27N5O2.HCl","Hydrochloride","EMD68843,SB659746A","Cl.NC(=O)C1=CC2=C(O1)C=CC(=C2)N3CCN(CCCCC4=C[NH]C5=C4C=C(C=C5)C#N)CC3",4.918,2,2,7]
["S4261","EUK 134","g11","L4000-08","in 10mM DMSO","Beta Amyloid","Neuronal Signaling","EUK 134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.",416.74,"81065-76-1",{"v":83,"d":"83.00"},199.16,{"v":13,"d":"13.00"},31.19,"http://selleckchem.com/products/euk-134.html","C18H18ClMnN2O4","Complex","N/A","COC1=C2O[Mn]|3|4(Cl)OC5=C(OC)C=CC=C5C=N|3CCN|4=CC2=CC=C1",3.526,4,0,2]
["S4265","Nicaraven","h11","L4000-08","in 10mM DMSO","Others","Others","Nicaraven is a hydroxyl radical scavenger with antivasospastic and neuroprotective effects.",284.31,"79455-30-4",{"v":57,"d":"57.00"},200.49,{"v":57,"d":"57.00"},200.49,"http://selleckchem.com/products/nicaraven.html","C15H16N4O2","free base","N/A","CC(CNC(=O)C1=CN=CC=C1)NC(=O)C2=CN=CC=C2",-0.029,4,2,5]
["S4266","Brimonidine Tartrate","a2","L4000-09","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Brimonidine Tartrate(UK 1434 Tartrate) is a highly selective α-adrenergic receptor agonist with EC50 of 0.45 nM for the α2A adrenoreceptor, and used to treat open-angle glaucoma or ocular hypertension.",442.22,"70359-46-5",{"v":88,"d":"88.00"},{"v":199,"d":"199.00"},{"v":75,"d":"75.00"},{"v":169.6,"d":"169.60"},"http://selleckchem.com/products/brimonidine-tartrate.html","C15H16BrN5O6","Tartrate","UK 1434 Tartrate","OC(C(O)C(O)=O)C(O)=O.BrC1=C2N=CC=NC2=CC=C1NC3=NCCN3",-0.426,5,4,5]
["S4268","Flufenamic acid","b2","L4000-09","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Flufenamic Acid is an anti-inflammatory agent, and also acts as an ion channel modulator.",281.23,"530-78-9",{"v":56,"d":"56.00"},199.13,"<1","N/A","http://selleckchem.com/products/flufenamic-acid.html","C14H10F3NO2","free base","N/A","OC(=O)C1=CC=CC=C1NC2=CC=CC(=C2)C(F)(F)F",3.952,1,1,4]
["S4270","Oxiracetam","c2","L4000-09","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Oxiracetam (ISF 2522), a cyclic derivative of gamma-aminobutyric acid (GABA), is used as a nootropic drug to improve memory and learning.",158.16,"62613-82-5",{"v":31,"d":"31.00"},{"v":196,"d":"196.00"},{"v":31,"d":"31.00"},{"v":196,"d":"196.00"},"http://selleckchem.com/products/oxiracetam.html","C6H10N2O3","free base","ISF 2522","NC(=O)CN1CC(O)CC1=O",-2.143,2,2,2]
["S4274","Rotigotine","d2","L4000-09","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Rotigotine(N-0923) is a dopamine receptor agonist, used in the treatment of Parkinson's disease and restless legs syndrome.",315.47,"99755-59-6",{"v":63,"d":"63.00"},{"v":199.7,"d":"199.70"},"<1","N/A","http://selleckchem.com/products/rotigotine.html","C19H25NOS","free base","N-0923","CCCN(CCC1=CC=CS1)C2CCC3=C(C2)C=CC=C3O",4.986,0,1,6]
["S4277","Bambuterol HCl","e2","L4000-09","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Bambuterol HCl(Bambuterol hydrochloride,KWD-2183 hydrochloride) is a potent β-adrenoceptor agonist, used in the treatment of asthma.",{"v":403.9,"d":"403.90"},"81732-46-9",{"v":80,"d":"80.00"},198.07,{"v":72,"d":"72.00"},178.26,"http://selleckchem.com/products/bambuterol-hci.html","C18H29N3O5.HCl","Hydrochloride","Bambuterol hydrochloride,KWD-2183 hydrochloride","Cl.CN(C)C(=O)OC1=CC(=CC(=C1)OC(=O)N(C)C)C(O)CNC(C)(C)C",2.109,4,2,8]
["S4278","Carteolol HCl","f2","L4000-09","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Carteolol HCl(Carteolol hydrochloride,OPC-1085 hydrochloride) is a β-adrenoceptor antagonist, used for the treatment of glaucoma.",328.83,"51781-21-6",{"v":65,"d":"65.00"},197.67,{"v":65,"d":"65.00"},197.67,"http://selleckchem.com/products/carteolol-hci.html","C16H25ClN2O3","Hydrochloride","Carteolol hydrochloride,OPC-1085 hydrochloride","Cl.CC(C)(C)NCC(O)COC1=C2CCC(=O)NC2=CC=C1",1.664,2,3,6]
["S4280","Meclofenoxate (Centrophenoxine) HCl","g2","L4000-09","in 10mM DMSO","Transferase","Metabolism","Meclofenoxate (Centrophenoxine) HCl is an anti-aging drug used to treat the symptoms of senile dementia and Alzheimer's disease, and also inhibits the activity of cholinephosphotransferase.",294.17,"3685-84-5",{"v":58,"d":"58.00"},197.16,{"v":58,"d":"58.00"},197.16,"http://selleckchem.com/products/meclofenoxate-centrophenoxine-hci.html","C12H17Cl2NO3","Hydrochloride","Centrophenoxine","Cl.CN(C)CCOC(=O)COC1=CC=C(Cl)C=C1",2.705,3,0,7]
["S4281","Tasimelteon","h2","L4000-09","in 10mM DMSO","MT Receptor","Neuronal Signaling","Tasimelteon (BMS 214778, VEC 162) is a selective dual melatonin receptor (MT1/MT2) agonist with 2.1-4.4 times greater affinity for the MT2 receptor believed to mediate circadian rhythm phase-shifting (Ki = 0.0692 nM and Ki = 0.17 nM in NIH-3T3 and CHOeK1 cells, respectively), than for the MT1 receptor (Ki = 0.304 nM and Ki = 0.35 nM, respectively).",245.32,"609799-22-6",{"v":49,"d":"49.00"},199.74,{"v":-1,"d":"-1.00"},-4.08,"https://www.selleckchem.com/products/tasimelteon.html","C15H19NO2","free base","BMS 214778, VEC 162","CCC(=O)NCC1CC1C2=C3CCOC3=CC=C2",2.203,2,1,4]
["S4283","Cyclobenzaprine HCl","a3","L4000-09","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Cyclobenzaprine HCl(Cyclobenzaprine hydrochloride) is a muscle relaxant by blocking pain sensations, used for the treatment of muscle spasms; A 5-HT2 receptor antagonist.",311.85,"6202-23-9",{"v":62,"d":"62.00"},198.81,{"v":62,"d":"62.00"},198.81,"http://selleckchem.com/products/cyclobenzaprine-hci.html","C20H22ClN","Hydrochloride","Cyclobenzaprine hydrochloride","Cl.CN(C)CCC=C1C2=C(C=CC=C2)C=CC3=C1C=CC=C3",4.709,0,0,3]
["S4284","Chloroprocaine HCl","b3","L4000-09","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Chloroprocaine HCl is a local anesthetic during surgical procedures.",307.22,"3858-89-7",{"v":61,"d":"61.00"},198.55,{"v":61,"d":"61.00"},198.55,"http://selleckchem.com/products/chloroprocaine-hci.html","C13H20Cl2N2O2","Hydrochloride","N/A","Cl.CCN(CC)CCOC(=O)C1=C(Cl)C=C(N)C=C1",2.821,2,1,7]
["S4289","Metoclopramide HCl","c3","L4000-09","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Metoclopramide HCl(Metoclopramide hydrochloride) is a selective dopamine D2 receptor antagonist, used for the treatment of nausea and vomiting.",336.26,"7232-21-5",{"v":67,"d":"67.00"},199.25,{"v":67,"d":"67.00"},199.25,"http://selleckchem.com/products/metoclopramide-hcl.html","C14H23Cl2N3O2","Hydrochloride","Metoclopramide hydrochloride","Cl.CCN(CC)CCNC(=O)C1=CC(=C(N)C=C1OC)Cl",2.157,2,2,7]
["S4291","Labetalol HCl","d3","L4000-09","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Labetalol HCl(AH-5158 hydrochloride,Labetalol hydrochloride,Sch-15719W) is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors, used in the treatment of high blood pressure.",364.87,"32780-64-6",{"v":72,"d":"72.00"},197.33,{"v":8,"d":"8.00"},21.93,"http://selleckchem.com/products/labetalol-hcl.html","C19H25ClN2O3","Hydrochloride","AH-5158 hydrochloride,Labetalol hydrochloride,Sch-15719W","Cl.CC(CCC1=CC=CC=C1)NCC(O)C2=CC(=C(O)C=C2)C(N)=O",2.737,1,4,8]
["S4292","Diphenidol HCl","e3","L4000-09","in 10mM DMSO","AChR","Neuronal Signaling","Diphenidol HCl(Diphenidol hydrochloride) is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02, respectively, used in the treatment of vomiting and vertigo.",345.91,"3254-89-5",{"v":69,"d":"69.00"},199.47,{"v":13,"d":"13.00"},37.58,"http://selleckchem.com/products/diphenidol-hcl.html","C21H28ClNO","Hydrochloride","Diphenidol hydrochloride","Cl.OC(CCCN1CCCCC1)(C2=CC=CC=C2)C3=CC=CC=C3",4.774,0,0,6]
["S4293","Promethazine HCl","f3","L4000-09","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Promethazine HCl is a potent histamine H1 receptor antagonist, used as a sedative and antiallergic medication.",320.88,"58-33-3",{"v":64,"d":"64.00"},199.45,{"v":64,"d":"64.00"},199.45,"http://selleckchem.com/products/promethazine-hcl.html","C17H21ClN2S","Hydrochloride","N/A","Cl.CC(CN1C2=CC=CC=C2SC3=C1C=CC=C3)N(C)C",4.772,0,0,3]
["S4294","Procainamide HCl","g3","L4000-09","in 10mM DMSO","DNA Methyltransferase,Sodium Channel","Transmembrane Transporters","Procainamide HCl is a sodium channel blocker, and also a DNA methyltransferase inhibitor, used in the treatment of cardiac arrhythmias.",271.79,"614-39-1",{"v":54,"d":"54.00"},198.68,{"v":54,"d":"54.00"},198.68,"http://selleckchem.com/products/procainamide-hcl.html","C13H22ClN3O","Hydrochloride","N/A","Cl.CCN(CC)CCNC(=O)C1=CC=C(N)C=C1",1.509,1,2,6]
["S4295","Meclofenamate Sodium","h3","L4000-09","in 10mM DMSO","COX,FTO","Neuronal Signaling","Meclofenamate Sodium(CI 583) is a dual COX-1/COX-2 inhibitor with IC50 of 40 nM and 50 nM, respectively, used in the treatment of joint, muscular pain, arthritis and dysmenorrhea. Meclofenamate Sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat mass and obesity-associated (FTO) enzyme inhibitor.",318.13,"6385-02-0",{"v":63,"d":"63.00"},198.03,{"v":63,"d":"63.00"},198.03,"http://selleckchem.com/products/meclofenamate-sodium.html","C14H11Cl2NO2.Na","Sodium Salt","CI 583","CC1=C(Cl)C(=C(Cl)C=C1)NC2=CC=CC=C2C(=O)O[Na]",4.915,2,1,4]
["S4296","Salmeterol Xinafoate","a4","L4000-09","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Salmeterol Xinafoate(GR 33343X xinafoate,Salmetedur) is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms.",603.75,"94749-08-3",{"v":100,"d":"100.00"},165.63,"<1","N/A","http://selleckchem.com/products/salmeterol-xinafoate.html","C36H45NO7","xinafoate","GR 33343X xinafoate,Salmetedur","OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC2=CC=CC=C2.OC(=O)C3=C(O)C4=CC=CC=C4C=C3",3.673,2,5,17]
["S4301","(R)-(+)-Atenolol HCl","b4","L4000-09","in 10mM DMSO","Adrenergic Receptor","Others","(R)-(+)-Atenolol binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists.",266.34,"56715-13-0",{"v":53,"d":"53.00"},198.99,{"v":18,"d":"18.00"},67.58,"http://selleckchem.com/products/atenolol.html","C9H16ClNO2","Hydrochloride","N/A","Cl.CC(=O)OC1CN2CCC1CC2",0.939,2,0,2]
["S4305","Anisotropine Methylbromide","c4","L4000-09","in 10mM DMSO","Others","Others","Anisotropine Methylbromide is a quaternary ammonium compound, used as treatment adjunct in peptic ulcer.",362.35,"80-50-2",{"v":25,"d":"25.00"},68.99,{"v":72,"d":"72.00"},{"v":198.7,"d":"198.70"},"http://www.selleckchem.com/products/anisotropine-methylbromide.html","C17H32BrNO2","methylbromide","N/A","[Br-].CCCC(CCC)C(=O)OC1CC2CCC(C1)[N+]2(C)C",-0.169,2,0,7]
["S4309","Bromocriptine Mesylate","d4","L4000-09","in 10mM DMSO","Others","Others","Bromocriptine, an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.",{"v":750.7,"d":"750.70"},"22260-51-1",{"v":100,"d":"100.00"},133.21,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/bromocriptine-mesylate.html","C32H40BrN5O5.CH4O3S","Mesylate","N/A","CC(C)CC1N2C(=O)C(NC(=O)C3CN(C)C4CC5=C(Br)[NH]C6=C5C(=CC=C6)C4=C3)(OC2(O)C7CCCN7C1=O)C(C)C.C[S](O)(=O)=O",3.949,4,2,5]
["S4317","Clorgyline HCl","e4","L4000-09","in 10mM DMSO","MAO","Others","Clorgiline is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A).",308.63,"17780-75-5",{"v":62,"d":"62.00"},200.89,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/clorgyline-hcl.html","C13H15Cl2NO.HCl","hydrochloride","N/A","Cl.CN(CCCOC1=CC=C(Cl)C=C1Cl)CC#C",4.917,1,0,6]
["S4319","Dibenzepine HCl","f4","L4000-09","in 10mM DMSO","Others","Others","Dibenzepine is tricyclic antidepressants with two benzene rings fused to an azepine group.",331.84,"315-80-0",{"v":19,"d":"19.00"},57.26,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/dibenzepine-hcl.html","C18H21N3O.HCl","hydrochloride","N/A","Cl.CN(C)CCN1C(=O)C2=C(C=CC=C2)N(C)C3=C1C=CC=C3",3.267,1,0,3]
["S4320","Dimaprit 2HCl","g4","L4000-09","in 10mM DMSO","Histamine Receptor","Others","Dimaprit is a histamine type 2 receptor agonist.",234.19,"23256-33-9",{"v":47,"d":"47.00"},200.69,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/dimaprit-2hcl.html","C6H15N3S.2HCl","Dihydrochloride","N/A","Cl.Cl.CN(C)CCCSC(N)=N",1.388,0,1,5]
["S4329","Hemicholinium Bromide","h4","L4000-09","in 10mM DMSO","Others","Others","Hemicholinium-3 is a drug which blocks the reuptake of choline by the high-affinity choline transporter (ChT) at the presynapse.",574.35,"312-45-8",{"v":27,"d":"27.00"},47.01,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/hemicholinium-bromide.html","C24H34N2O4.2Br","Bromide","N/A","[Br-].[Br-].C[N+]1(C)CCOC(O)(C1)C2=CC=C(C=C2)C3=CC=C(C=C3)C4(O)C[N+](C)(C)CCO4",-5.397,2,0,3]
["S4334","Mesoridazine Besylate","a5","L4000-09","in 10mM DMSO","Others","Others","N/A",544.75,"32672-69-8",{"v":100,"d":"100.00"},183.57,{"v":100,"d":"100.00"},183.57,"http://www.selleckchem.com/products/mesoridazine-besylate.html","C27H32N2O4S3","besylate","N/A","CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)[S](C)=O.O[S](=O)(=O)C5=CC=CC=C5",5.614,1,0,5]
["S4335","Metaproterenol Sulfate","b5","L4000-09","in 10mM DMSO","Others","Others","N/A",520.59,"5874-97-5",{"v":100,"d":"100.00"},192.09,{"v":100,"d":"100.00"},192.09,"http://www.selleckchem.com/products/metaproterenol-sulfate.html","C22H36N2O10S","sulfate","Orciprenaline Sulfate","CC(C)NCC(O)C1=CC(=CC(=C1)O)O.CC(C)NCC(O)C2=CC(=CC(=C2)O)O.O[S](O)(=O)=O",1.591,0,8,8]
["S4336","Metaraminol Bitartrate","c5","L4000-09","in 10mM DMSO","Others","Others","N/A",317.29,"33402-03-8",{"v":63,"d":"63.00"},198.56,{"v":63,"d":"63.00"},198.56,"http://www.selleckchem.com/products/metaraminol-bitartrate.html","C13H19NO8","bitartrate","Metaradrine Bitartrate","CC(N)C(O)C1=CC=CC(=C1)O.OC(C(O)C(O)=O)C(O)=O",-3.582,2,5,5]
["S4338","Methoxamine HCl","d5","L4000-09","in 10mM DMSO","Others","Others","Methoxamine is an α1-adrenergic receptor agonist, it induces vasoconstriction of skin and splanchnic blood vessels.",247.72,"61-16-5",{"v":50,"d":"50.00"},201.84,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/methoxamine-hcl.html","C11H17NO3.HCl","Hydrochloride","Vasoxine HCl","Cl.COC1=CC(=C(OC)C=C1)C(O)C(C)N",1.151,2,2,4]
["S4342","Nialamide","e5","L4000-09","in 10mM DMSO","MAO","Others","Nialamide is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class used as an antidepressant and anxiolytic.",298.34,"51-12-7",{"v":59,"d":"59.00"},197.76,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/nialamide.html","C16H18N4O2","Free Base","N/A","O=C(CCNNC(=O)C1=CC=NC=C1)NCC2=CC=CC=C2",0.287,3,3,7]
["S4343","Oxethazaine","f5","L4000-09","in 10mM DMSO","Others","Others","Oxethazaine is a strong local anaesthetic, which acts in a number of ways to numb the walls of the stomach and relieve the pain associated with hyperacidic conditions.",467.64,"126-27-2",{"v":87,"d":"87.00"},186.04,"<1","N/A","http://selleckchem.com/products/oxethazaine.html","C28H41N3O3","free base","Oxethacaine","CN(C(=O)CN(CCO)CC(=O)N(C)C(C)(C)CC1=CC=CC=C1)C(C)(C)CC2=CC=CC=C2",3.286,2,1,12]
["S4344","Oxprenolol HCl","g5","L4000-09","in 10mM DMSO","Adrenergic Receptor","Others","Oxprenolol is a non-selective beta blocker with some intrinsic sympathomimetic activity.",301.81,"6452-73-9",{"v":60,"d":"60.00"},{"v":198.8,"d":"198.80"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/oxprenolol-hcl.html","C15H23NO3.HCl","hydrochloride","N/A","Cl.CC(C)NCC(O)COC1=CC=CC=C1OCC=C",2.614,2,2,9]
["S4349","Procyclidine HCl","h5","L4000-09","in 10mM DMSO","NMDAR","Others","Procyclidine HCl blocks the effects of certain chemicals in the brain, and thus is used to treat Parkinson's disease or extrapyramidal side-effects caused by other medicines.",{"v":323.9,"d":"323.90"},"1508-76-5",{"v":64,"d":"64.00"},197.59,{"v":14,"d":"14.00"},43.22,"http://www.selleckchem.com/products/procyclidine-hcl.html","C19H30ClNO","hydrochloride","N/A","Cl.OC(CCN1CCCC1)(C2CCCCC2)C3=CC=CC=C3",4.343,0,0,5]
["S4353","Terfenadine","a6","L4000-09","in 10mM DMSO","Calcium Channel,Caspase,Histamine Receptor,NCX,Potassium Channel","Transmembrane Transporters","Terfenadine is an antihistamine, generally completely metabolizes to the active form fexofenadine in the liver by the enzyme cytochrome P450 CYP3A4 isoform.  Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.",471.67,"50679-08-8",{"v":94,"d":"94.00"},199.29,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/terfenadine.html","C32H41NO2","Free Base","N/A","CC(C)(C)C1=CC=C(C=C1)C(O)CCCN2CCC(CC2)C(O)(C3=CC=CC=C3)C4=CC=CC=C4",6.498,0,1,9]
["S4357","Tacrine HCl","b6","L4000-09","in 10mM DMSO","AChR","Neuronal Signaling","Tacrine is a centrally acting anticholinesterase and indirect cholinergic agonist. Tacrine hydrochloride hydrate is an inhibitor of both acetyl (AChE) and butyryl-cholinestrase (BChE) with IC50s of 31 nM and 25.6 nM, respectively.",234.72,"1684-40-8",{"v":46,"d":"46.00"},195.98,{"v":46,"d":"46.00"},195.98,"http://www.selleckchem.com/products/tacrine-hcl.html","C13H14N2.HCl","hydrochlorid","N/A","Cl.NC1=C2C=CC=CC2=NC3=C1CCCC3",3.172,1,1,0]
["S4358","Pimozide","c6","L4000-09","in 10mM DMSO","5-HT Receptor,Adrenergic Receptor,Dopamine Receptor,STAT","Neuronal Signaling","Pimozide (Orap, R6238) is an antagonist of Dopamine Receptors with Ki of 0.83 nM, 3.0 nM and 6600 nM for dopamine D3, D2 and D1 receptors, respectively. Pimozide also exhibits binding affinity at 5-HT1A and α1-adrenoceptor with Ki of 310 nM and 39 nM, respectively. Pimozide is an antipsychotic drug with anti-tumor activity and suppresses STAT3 and STAT5 activity.",461.55,"2062-78-4",{"v":92,"d":"92.00"},199.33,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/pimozide.html","C28H29F2N3O","Free Base","Orap, R6238","FC1=CC=C(C=C1)C(CCCN2CCC(CC2)N3C(=O)NC4=CC=CC=C34)C5=CC=C(F)C=C5",5.521,1,1,7]
["S4373","Dicyclomine HCl","d6","L4000-09","in 10mM DMSO","Others","Others","Dicyclomine is an anticholinergic drug, a chemical released from nerves that stimulates muscles, by blocking the receptors for acetylcholine on smooth muscle (a type of muscle).",345.95,"67-92-5",{"v":22,"d":"22.00"},63.59,{"v":69,"d":"69.00"},199.45,"http://www.selleckchem.com/products/dicyclomine-hcl.html","C19H36ClNO2","Hydrochloride","Dicycloverine HCl","Cl.CCN(CC)CCOC(=O)C1(CCCCC1)C2CCCCC2",5.487,2,0,8]
["S4376","Aceclidine HCl","e6","L4000-09","in 10mM DMSO","Others","Others","Aceclidine is a parasympathomimetic miotic agent used to decreases intraocular pressure.",205.68,"6109-70-2",{"v":41,"d":"41.00"},199.34,{"v":41,"d":"41.00"},199.34,"http://www.selleckchem.com/products/aceclidine-hcl.html","C9H16ClNO2","hydrochloride","N/A","Cl.CC(=O)OC1CN2CCC1CC2",0.939,2,0,2]
["S4377","Imipramine HCl","f6","L4000-09","in 10mM DMSO","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Imipramine (Melipramine,G 22355) is a tricyclic antidepressant (TCA) of the dibenzazepine group, mainly used in the treatment of major depression and enuresis (inability to control urination).",316.87,"113-52-0",{"v":63,"d":"63.00"},198.82,{"v":63,"d":"63.00"},198.82,"http://www.selleckchem.com/products/imipramine-hcl.html","C19H25ClN2","hydrochloride","Melipramine HCl,G 22355","Cl.CN(C)CCCN1C2=C(CCC3=C1C=CC=C3)C=CC=C2",4.769,0,0,4]
["S4380","Nomifensine Maleate","g6","L4000-09","in 10mM DMSO","Dopamine Receptor","Others","Nomifensine is a dopamine reuptake inhibitor that increases the amount of synaptic dopamine available to receptors by blocking dopamine's re-uptake transporter.",{"v":354.4,"d":"354.40"},"32795-47-4",{"v":71,"d":"71.00"},200.34,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/nomifensine-maleate.html","C20H22N2O4","Maleate","N/A","CC#CCOOOO.CN1CC(C2=CC=CC=C2)C3=CC=CC(=C3C1)N",3.582,3,1,5]
["S4381","Proadifen HCl","h6","L4000-09","in 10mM DMSO","CYP450","Others","Proadifen is an inhibitor of cytochrome P450 enzymes, preventing some types of drug metabolism.",390.01,"62-68-0",{"v":77,"d":"77.00"},197.43,{"v":77,"d":"77.00"},197.43,"http://www.selleckchem.com/products/proadifen-hcl.html","C23H32ClNO2","hydrochloride","SKF 525-A HCl","Cl.CCCC(C(=O)OCCN(CC)CC)(C1=CC=CC=C1)C2=CC=CC=C2",5.762,2,0,11]
["S4382","Pyrilamine Maleate","a7","L4000-09","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Pyrilamine Maleate (Mepyramine)is a histamine H1 receptor inverse agonist, it binds to a G protein-coupled form of the receptor and promotes a G protein-coupled inactive state of the H1 receptor that interferes with the Gq/11-mediated signaling.",401.46,"59-33-6",{"v":80,"d":"80.00"},199.27,{"v":80,"d":"80.00"},199.27,"https://www.selleckchem.com/products/pyrilamine-maleate.html","C17H23N3O1.C4H4O4","maleate","Mepyramine Maleate","COC1=CC=C(CN(CCN(C)C)C2=CC=CC=N2)C=C1.OC(=O)\\C=C/C(O)=O",{"v":0.09,"d":"0.090"},4,0,9]
["S4389","Bephenium Hydroxynaphthoate","b7","L4000-09","in 10mM DMSO","AChR,Parasite","Neuronal Signaling","Bephenium(NSC 759245) is an activator of B-type Acetylcholine receptor (AChR). Bephenium selectively activates the Hco-L-AChR1 subtype made of Hco-UNC-29.1, Hco-UNC-38, Hco-UNC-63, Hco-ACR-8 subunits. Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis.",443.53,"3818-50-6",{"v":88,"d":"88.00"},198.41,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/bephenium-hydroxynaphthoate.html","C28H29NO4","hydroxynaphthoa","NSC 759245","C[N+](C)(CCOC1=CC=CC=C1)CC2=CC=CC=C2.OC3=C(C=C4C=CC=CC4=C3)C([O-])=O",2.833,1,1,7]
["S4391","Camylofin Chlorhydrate","c7","L4000-09","in 10mM DMSO","Others","Others","N/A",393.39,"54-30-8",{"v":78,"d":"78.00"},198.28,{"v":78,"d":"78.00"},198.28,"http://www.selleckchem.com/products/camylofin-chlorhydrate.html","C19H34Cl2N2O2","chlorhydrate","Camylofine Chlorhydrate","Cl.Cl.CCN(CC)CCNC(C(=O)OCCC(C)C)C1=CC=CC=C1",4.391,2,1,12]
["S4406","Pindolol","d7","L4000-09","in 10mM DMSO","5-HT Receptor","Others","N/A",248.32,"13523-86-9",{"v":50,"d":"50.00"},201.35,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/pindolol.html","C14H20N2O2","Free Base","N/A","CC(C)NCC(O)COC1=C2C=C[NH]C2=CC=C1",1.925,1,3,6]
["S4409","Quipazine Maleate","e7","L4000-09","in 10mM DMSO","Others","Others","N/A",329.35,"5786-68-5",{"v":66,"d":"66.00"},200.39,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/quipazine-maleate.html","C13H15N3.C4H4O4","Maleate","N/A","OC(=O)\\C=C/C(O)=O.C1CN(CCN1)C2=NC3=C(C=CC=C3)C=C2",-0.527,3,1,3]
["S4416","Trimipramine Maleate","f7","L4000-09","in 10mM DMSO","Others","Others","N/A",410.51,"521-78-8",{"v":82,"d":"82.00"},199.75,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/trimipramine-maleate.html","C24H30N2O4","maleate","N/A","CC(CN(C)C)CN1C2=C(CCC3=CC=CC=C13)C=CC=C2.OC(=O)\\C=C/C(O)=O",{"v":1.84,"d":"1.840"},2,0,6]
["S4422","Nitenpyram","g7","L4000-09","in 10mM DMSO","AChR,Parasite","Neuronal Signaling","Nitenpyram(Bestguard,Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.",270.72,"150824-47-8",{"v":54,"d":"54.00"},199.47,{"v":54,"d":"54.00"},199.47,"http://selleckchem.com/products/nitenpyram.html","C11H15ClN4O2","free base","Bestguard,Capstar","CCN(CC1=CC=C(Cl)N=C1)\\C(NC)=C\\[N+]([O-])=O",{"v":1.7,"d":"1.700"},1,1,6]
["S4505","Vinblastine (NSC-49842) sulfate","h7","L4000-09","in 10mM DMSO","AChR,Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,Autophagy,Microtubule Associated","Cytoskeletal Signaling","Vinblastine sulfate (NSC49842, Vincaleukoblastine sulfate salt, 29060-LE, Exal, Velban, Velbe) inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM in a cell-free assay, used to treat certain kinds of cancer. Vinblastine sulfate induces autophagy and apoptosis.",909.05,"143-67-9",{"v":100,"d":"100.00"},{"v":110,"d":"110.00"},"<1","N/A","http://selleckchem.com/products/vinblastine-sulfate.html","C46H58N4O9.H2SO4","sulfate","Vincaleukoblastine sulfate salt, 29060-LE, Exal, Velban, Velbe","CCC1(O)CC2CN(CCC3=C([NH]C4=CC=CC=C34)C(C2)(C(=O)OC)C5=C(OC)C=C6N(C)C7C(O)(C(OC(C)=O)C8(CC)C=CCN9CCC7(C89)C6=C5)C(=O)OC)C1.O[S](O)(=O)=O",{"v":4.28,"d":"4.280"},7,1,10]
["S4506","Acetazolamide","a8","L4000-09","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Acetazolamide (Diamox), a potent carbonic anhydrase (CA) inhibitor, is commonly used in clinical practice as an immediate and readily available option for acute reduction of intraocular pressure(IOP).",222.25,"59-66-5",{"v":44,"d":"44.00"},197.98,"<1","N/A","http://selleckchem.com/products/acetazolamide.html","C4H6N4O3S2","free base","Diamox","CC(=O)NC1=NN=C(S1)[S](N)(=O)=O",-1.329,5,2,2]
["S4508","2,2,2-Tribromoethanol","b8","L4000-09","in 10mM DMSO","Others","Others","2,2,2-Tribromoethanol (TBE, Tribromoethanol) is an organic compound used to anesthetize animals.",282.76,"75-80-9",{"v":56,"d":"56.00"},198.05,{"v":56,"d":"56.00"},198.05,"http://selleckchem.com/products/2-2-2-tribromoethanol.html","C2H3Br3O","free base","TBE, Tribromoethanol","OCC(Br)(Br)Br",{"v":1.85,"d":"1.850"},0,1,1]
["S4509","4-Aminoantipyrine","c8","L4000-09","in 10mM DMSO","COX","Immunology & Inflammation","4-Aminoantipyrine(Ampyrone) is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. It is used as a reagent for biochemical reactions producing peroxides or phenols.",203.24,"83-07-8",{"v":40,"d":"40.00"},196.81,{"v":40,"d":"40.00"},196.81,"http://selleckchem.com/products/4-aminoantipyrine.html","C11H13N3O","free base","Ampyrone, NSC 60242, Metapirazone, Solnapyrin-A, Solvapyrin-A,  Minoazophene, Aminoazophene,  Aminoantipyrin","CN1N(C2=CC=CC=C2)C(=O)C(=C1C)N",0.021,1,1,1]
["S4512","Aceglutamide","d8","L4000-09","in 10mM DMSO","Others","Others","Aceglutamide (α-N-Acetyl-L-glutamine, N2-Acetylglutamine) is a psychostimulant, nootropic agent which functions as a prodrug to glutamine with improved potency and stability.",188.18,"2490-97-3",{"v":37,"d":"37.00"},196.62,{"v":37,"d":"37.00"},196.62,"http://selleckchem.com/products/aceglutamide.html","C7H12N2O4","free base","α-N-Acetyl-L-glutamine, N2-Acetylglutamine","CC(=O)NC(CCC(N)=O)C(O)=O",-1.587,3,2,5]
["S4516","(+)-Camphor","e8","L4000-09","in 10mM DMSO","Fungal,TRP Channel","Transmembrane Transporters","Camphor is a waxy, flammable, white or transparent solid with a strong aroma, often used to relieve pain, reduce itching and treat fungal infections. It can activate TRPV1  and TRPV3.",152.23,"464-49-3",{"v":30,"d":"30.00"},197.07,"<1","N/A","http://selleckchem.com/products/positive-rotation-camphor.html","C10H16O","free base","D-(+)-camphor, (1R)-(+)-camphor","CC1(C)C2CCC1(C)C(=O)C2",2.075,1,0,0]
["S4520","2-Aminoheptane","f8","L4000-09","in 10mM DMSO","Others","Others","2-Aminoheptane (Tuaminoheptanez, Tuamine, Heptamine, 1-Methylhexylamine, 2-Heptylamine) is a nasal decongestant drug which is a sympathomimetic stimulant and vasoconstrictor.",115.22,"123-82-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/2-aminoheptane.html","C7H17N","Free Base","Tuaminoheptanez, Tuamine, Heptamine, 1-Methylhexylamine, 2-Heptylamine","CCCCCC(C)N",{"v":1.97,"d":"1.970"},0,1,4]
["S4526","Fenbufen","g8","L4000-09","in 10mM DMSO","COX","Neuronal Signaling","Fenbufen (Lederfen, CL-82204) is an orally active phenylalkanoic derivative with anti-inflammatory, analgesic and antipyretic activity. It is a non-steroidal anti-inflammatory drug.",254.28,"36330-85-5",{"v":50,"d":"50.00"},196.63,"<1","N/A","http://selleckchem.com/products/fenbufen.html","C16H14O3","free base","Lederfen, CL-82204","OC(=O)CCC(=O)C1=CC=C(C=C1)C2=CC=CC=C2",2.933,2,0,5]
["S4529","Idramantone","h8","L4000-09","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Idramantone (Kemantane, 5-Hydroxy-2-adamantanone) is an immune agonist.",166.22,"20098-14-0",{"v":33,"d":"33.00"},198.53,{"v":33,"d":"33.00"},198.53,"http://selleckchem.com/products/idramantone.html","C10H14O2","free base","Kemantane, 5-Hydroxy-2-adamantanone","OC12CC3CC(C1)C(=O)C(C3)C2",0.783,1,0,0]
["S4535","Methylene Blue","a9","L4000-09","in 10mM DMSO","Dyes,Guanylate Cyclase,Microtubule Associated","GPCR & G Protein","Methylene Blue (Basic Blue 9, Tetramethylthionine chloride, methylthioninium chloride, CI-52015) is used as a dye in chromoendoscopy. It Inhibits tau filament formation with IC50 of 1.9μM. Also it inhibits soluble guanylyl cyclase.",319.85,"61-73-4",{"v":63,"d":"63.00"},196.97,{"v":63,"d":"63.00"},196.97,"http://selleckchem.com/products/methylene-blue.html","C16H18ClN3S","free base","Basic Blue 9, Tetramethylthionine chloride, methylthioninium chloride, CI-52015","[Cl-].CN(C)C1=CC2=C(C=C1)N=C3C=CC(C=C3S2)=[N+](C)C",0.369,1,0,1]
["S4539","Salicylic acid","b9","L4000-09","in 10mM DMSO","COX","Neuronal Signaling","Salicylic acid (2-Hydroxybenzoic acid) is a beta hydroxy acid that occurs as a natural compound in plants which is an inhibitor of ethylene biosynthesis and cyclooxygenase activity.",138.12,"69-72-7",{"v":27,"d":"27.00"},195.48,"<1","N/A","http://selleckchem.com/products/salicylic-acid.html","C7H6O3","free base","2-Hydroxybenzoic acid","OC(=O)C1=C(O)C=CC=C1",1.217,1,1,1]
["S4542","Trihexyphenidyl hydrochloride","c9","L4000-09","in 10mM DMSO","AChR","Neuronal Signaling","Trihexyphenidyl hydrochloride (Benzhexol, Artane) is an antiparkinsonian agent of the antimuscarinic class.",337.93,"52-49-3",{"v":7,"d":"7.00"},20.71,"<1","N/A","http://selleckchem.com/products/trihexyphenidyl-hydrochloride.html","C20H31NO.HCl","hydrochloride","Benzhexol hydrochloride, Artane hydrochloride","Cl.OC(CCN1CCCCC1)(C2CCCCC2)C3=CC=CC=C3",4.799,0,0,5]
["S4544","Urethane","d9","L4000-09","in 10mM DMSO","Bacterial","Microbiology","Urethane (Carbamic acid ethyl ester, Ethyl carbamate, Ethylurethane) is a kind of antineoplastic agent that is also used as a veterinary anesthetic. It is a intermediate in organic synthesis.",89.09,"51-79-6",{"v":17,"d":"17.00"},190.82,{"v":17,"d":"17.00"},190.82,"http://selleckchem.com/products/urethane.html","C3H7NO2","free base","Carbamic acid ethyl ester, Ethyl carbamate, Ethylurethane","CCOC(N)=O",0.159,2,1,2]
["S4569","Fluphenazine dihydrochloride","e9","L4000-09","in 10mM DMSO","Dopamine Receptor","GPCR & G Protein","Fluphenazine dihydrochloride (Prolixin) is a phenothiazine-class D1DR and D2DR inhibitor. It also inhibits  Histamine H1 Receptor.",510.44,"146-56-5",{"v":100,"d":"100.00"},195.91,{"v":100,"d":"100.00"},195.91,"http://selleckchem.com/products/fluphenazine-dihydrochloride.html","C22H26F3N3OS.2HCl","dihydrochloride","Prolixin","Cl.Cl.OCCN1CCN(CCCN2C3=C(SC4=CC=C(C=C24)C(F)(F)F)C=CC=C3)CC1",5.199,0,1,7]
["S4570","Halothane","f9","L4000-09","in 10mM DMSO","Others","Others","Halothane (Narcotane) is a general inhalation anesthetic used for induction and maintenance of general anesthesia.",197.38,"151-67-7","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/halothane.html","C2HBrClF3","free base","Narcotane","FC(F)(F)C(Cl)Br",2.509,0,0,1]
["S4571","Hexylresorcinol","g9","L4000-09","in 10mM DMSO","Tyrosinase","Proteases","Hexylresorcinol (4-Hexylresorcinol) is an organic compound with local anaesthetic, antiseptic and anthelmintic properties, is a potent inhibitor of mushroom tyrosinase. The IC50 values of hexylresorcinol for monophenolase is 1.24 μM and for diphenolase is 0.85 μM.",194.27,"136-77-6",{"v":38,"d":"38.00"},{"v":195.6,"d":"195.60"},"<1","N/A","http://selleckchem.com/products/hexylresorcinol.html","C12H18O2","free base","4-Hexylresorcinol","CCCCCCC1=C(O)C=C(O)C=C1",4.113,0,2,5]
["S4583","Butamben","h9","L4000-09","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.",193.24,"94-25-7",{"v":38,"d":"38.00"},196.65,{"v":38,"d":"38.00"},196.65,"http://selleckchem.com/products/butamben.html","C11H15NO2","free base","Butyl 4-aminobenzoate","CCCCOC(=O)C1=CC=C(N)C=C1",2.267,2,1,5]
["S4587","Pentylenetetrazol","a10","L4000-09","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Pentylenetetrazol (Pentylenetetrazole, Metrazole, pentetrazol, pentamethylenetetrazol, Corazol, Cardiazol, PTZ) displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GABA(A) receptor antagonist.",138.17,"54-95-5",{"v":27,"d":"27.00"},195.41,{"v":27,"d":"27.00"},195.41,"http://selleckchem.com/products/pentylenetetrazol.html","C6H10N4","Free Base","Pentylenetetrazole, Metrazole, pentetrazol, pentamethylenetetrazol, Corazol, Cardiazol, PTZ","C1CC[N]2N=NN=C2CC1",0.568,3,0,0]
["S4588","Docusate Sodium","b10","L4000-09","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","Docusate Sodium (Aerosol OT, Bis(2-ethylhexyl) sulfosuccinate sodium salt, Constonate) is a laxative used to treat constipation, for constipation due to the use of opiates it maybe used with a stimulant laxative, can be taken by mouth or rectally.",444.56,"577-11-7",{"v":88,"d":"88.00"},197.95,{"v":18,"d":"18.00"},40.49,"http://selleckchem.com/products/docusate-sodium.html","C20H37O7S.Na","sodium salt","Aerosol OT, Bis(2-ethylhexyl) sulfosuccinate sodium salt, Constonate","[Na+].CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)[S]([O-])(=O)=O",3.172,4,0,18]
["S4597","Lercanidipine hydrochloride","c10","L4000-09","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Lercanidipine is a calcium channel blocker of the dihydropyridine class.",648.19,"132866-11-6",{"v":66,"d":"66.00"},101.82,"<1","N/A","http://selleckchem.com/products/lercanidipine-hydrochloride.html","C36H41N3O6.HCl","hydrochloride","Zanidip (hydrochloride), Masnidipine (hydrochloride)","Cl.COC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OC(C)(C)CN(C)CCC(C3=CC=CC=C3)C4=CC=CC=C4)C",6.514,4,1,14]
["S4600","Benzyl alcohol","d10","L4000-09","in 10mM DMSO","Others","Others","Benzyl alcohol (Phenylmethanol, Benzenemethanol, Phenylcarbinol, Benzoyl alcohol) is used as a local anesthetic. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.",108.14,"100-51-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/benzyl-alcohol.html","C7H8O","free base","Phenylmethanol, Benzenemethanol, Phenylcarbinol, Benzoyl alcohol","OCC1=CC=CC=C1",1.225,0,1,1]
["S4609","Diflunisal","e10","L4000-09","in 10mM DMSO","COX","Neuronal Signaling","Diflunisal (Dolobid, Dolobis, Flovacil, Fluniget,MK-647) is a difluorophenyl derivate of salicylic acid and a nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic and anti-inflammatory properties. The mechanism of action of diflunisal is as a Cyclooxygenase Inhibitor.",{"v":250.2,"d":"250.20"},"22494-42-4",{"v":50,"d":"50.00"},199.84,"<1","N/A","http://selleckchem.com/products/diflunisal.html","C13H8F2O3","free base","Dolobid, Dolobis, Flovacil, Fluniget,MK-647","OC(=O)C1=C(O)C=CC(=C1)C2=C(F)C=C(F)C=C2",3.147,1,1,2]
["S4618","Fenoldopam mesylate","f10","L4000-09","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Fenoldopam (SKF 82526, Corlopam) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.",401.86,"67227-57-0",{"v":80,"d":"80.00"},199.07,"<1","N/A","http://selleckchem.com/products/fenoldopam-mesylate.html","C16H16ClNO3.CH4O3S","mesylate","SKF 82526 (mesylate), Fenoldopam methanesulfonate, Corlopam mesylate","C[S](O)(=O)=O.OC1=CC=C(C=C1)C2CNCCC3=C(Cl)C(=C(O)C=C23)O",2.639,0,4,1]
["S4619","Itopride hydrochloride","g10","L4000-09","in 10mM DMSO","AChR","Neuronal Signaling","Itopride hydrochloride (Ganaton, HSR803) is an AChE inhibitor. The IC50 of itopride with AChE is 2.04 +/- 0.27 μM.",394.89,"122892-31-3",{"v":78,"d":"78.00"},197.52,{"v":78,"d":"78.00"},197.52,"http://selleckchem.com/products/itopride-hydrochloride.html","C20H26N2O4.HCl","hydrochloride","Ganaton, HSR803","Cl.COC1=CC=C(C=C1OC)C(=O)NCC2=CC=C(OCCN(C)C)C=C2",3.093,4,1,9]
["S4623","Methylbenactyzine Bromide","h10","L4000-09","in 10mM DMSO","AChR","Neuronal Signaling","Methylbenactyzine Bromide (Gastrimade, Noinarin, Paragone, Semulgin) is a kind of muscarinic cholinergic receptor antagonist with antispasmodic activity.",422.36,"3166-62-9",{"v":84,"d":"84.00"},198.88,{"v":84,"d":"84.00"},198.88,"http://selleckchem.com/products/methylbenactyzine-bromide.html","C21H28NO3.Br","bromide","Gastrimade, Noinarin, Paragone, Semulgin","[Br-].CC[N+](C)(CC)CCOC(=O)C(O)(C1=CC=CC=C1)C2=CC=CC=C2",-0.322,2,0,9]
["S4625","Alcaftadine","a11","L4000-09","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Alcaftadine (Lastacaft, R89674) is a high affinity ligand for the H1 receptor, with a pKi (8.5) that is comparable with that of other H1 antihistamines. Alcaftadine is also an antagonist for H2 and H4 receptors with no affinity for the H3 receptor.",307.39,"147084-10-4",{"v":28,"d":"28.00"},91.09,"<1","N/A","http://selleckchem.com/products/alcaftadine.html","C19H21N3O","free base","Lastacaft, R89674","CN1CCC(CC1)=C2C3=C(CC[N]4C(=CN=C24)C=O)C=CC=C3",2.831,2,0,1]
["S4626","Ethosuximide","b11","L4000-09","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Ethosuximide(Zarontin) is a succinimide anticonvulsant, used mainly in absence seizures; A calcium channel blocker.",141.17,"77-67-8",{"v":28,"d":"28.00"},198.34,{"v":28,"d":"28.00"},198.34,"http://selleckchem.com/products/ethosuximide.html","C7H11NO2","free base","Zarontin","CCC1(C)CC(=O)NC1=O",0.543,2,1,1]
["S4628","(+/-)-Sulfinpyrazone","c11","L4000-09","in 10mM DMSO","COX","Neuronal Signaling","Sulfinpyrazone (G-28315, NSC 75925) is one of the most studied platelet COX inhibitors, also a uricosuric agent that competitively inhibits uric acid reabsorption in kidney proximal tubules.",404.48,"57-96-5",{"v":80,"d":"80.00"},197.78,"<1","N/A","http://selleckchem.com/products/sulfinpyrazone.html","C23H20N2O3S","free base","G-28315, NSC 75925","O=C1C(CC[S](=O)C2=CC=CC=C2)C(=O)N(N1C3=CC=CC=C3)C4=CC=CC=C4",3.434,3,0,6]
["S4630","Diazoxide","d11","L4000-09","in 10mM DMSO","ADC Cytotoxin,Potassium Channel","Transmembrane Transporters","Diazoxide (Sch-6783, SRG-95213, Proglycem) is a well-known small molecule that activates KATP channels in the smooth muscle of blood vessels and pancreatic beta-cells by increasing membrane permeability to potassium ions.",230.67,"364-98-7",{"v":46,"d":"46.00"},199.42,"<1","N/A","http://selleckchem.com/products/diazoxide.html","C8H7ClN2O2S","free base","Sch-6783, SRG-95213, Proglycem","CC1=NC2=CC=C(Cl)C=C2[S](=O)(=O)N1",1.196,3,1,0]
["S4631","Prochlorperazine dimaleate salt","e11","L4000-09","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Prochlorperazine dimaleate (Prochlorperazin, Compazine, Capazine, Stemetil) is a dopamine (D2) receptor antagonist.",606.09,"84-02-6",{"v":74,"d":"74.00"},122.09,"<1","N/A","http://selleckchem.com/products/prochlorperazine.html","C20H24ClN3S.C8H8O8","dimaleate","Prochlorperazin, Compazine, Capazine, Stemetil","CN1CCN(CCCN2C3=C(SC4=C2C=C(Cl)C=C4)C=CC=C3)CC1.OC(=O)\\C=C/C(O)=O.OC(=O)\\C=C/C(O)=O",-1.295,4,0,8]
["S4635","Cyproheptadine hydrochloride sesquihydrate","f11","L4000-09","in 10mM DMSO","5-HT Receptor,SETD","Neuronal Signaling","Cyproheptadine hydrochloride (Periactin, Peritol) is non-selective 5HT2 antagonist with IC50 of 0.6 nM. Also a SETD7/9 inhibitor.",350.88,"41354-29-4",{"v":70,"d":"70.00"},{"v":199.5,"d":"199.50"},"<1","N/A","https://www.selleckchem.com/products/cyproheptadine-hydrochloride-sesquihydrate.html","C21H21N.HCl.3/2H2O","hydrochloride sesquihydrate","Periactin hydrochloride, Peritol","O.O.O.Cl.Cl.CN1CCC(CC1)=C2C3=CC=CC=C3C=CC4=CC=CC=C24.CN5CCC(CC5)=C6C7=CC=CC=C7C=CC8=CC=CC=C68",5.478,0,0,0]
["S4637","Prasugrel Hydrochloride","g11","L4000-09","in 10mM DMSO","P2 Receptor","Neuronal Signaling","Prasugrel hydrochloride (Prasugrel HCl, LY640315,PCR 4099 Hydrochloride)  is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.",{"v":409.9,"d":"409.90"},"389574-19-0",{"v":46,"d":"46.00"},112.22,"<1","N/A","http://selleckchem.com/products/prasugrel-hydrochloride.html","C20H20FNO3S.HCl","hydrochloride","Prasugrel HCl, LY640315,PCR 4099 Hydrochloride","Cl.CC(=O)OC1=CC2=C(CCN(C2)C(C(=O)C3CC3)C4=C(F)C=CC=C4)S1",4.183,3,0,6]
["S4648","Dantrolene sodium hemiheptahydrate","h11","L4000-09","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Dantrolene sodium hemiheptahydrate (Dantrium) is a skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber.",399.29,"24868-20-0",{"v":14,"d":"14.00"},35.06,"<1","N/A","https://www.selleckchem.com/products/dantrolene-sodium-s4648.html","C14H9N4O5.7/2H2O.Na","Sodium salt hemiheptahydrate","Dantrolene sodium salt, Dantrium, Sodium dantrolene","CCC1CN2CCC1CC2C(O)C3=C4C=C(OC)C=CC4=NC=C3",3.124,2,1,4]
["S4649","Atipamezole hydrochloride","a2","L4000-10","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Atipamezole (Antisedan, MPV1248) is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. Atipamezole hydrochloride is hydrochloride form of atipamezole.",248.75,"104075-48-1",{"v":12,"d":"12.00"},48.24,{"v":21,"d":"21.00"},84.42,"http://selleckchem.com/products/atipamezole-hydrochloride.html","C14H16N2.HCl","hydrochloride","Antisedan, MPV-1248 hydrochloride, MPV1248 hydrochloride, MPV 1248 hydrochloride","Cl.CCC1(CC2=C(C1)C=CC=C2)C3=C[NH]C=N3",3.531,1,1,2]
["S4650","Atipamezole","b2","L4000-10","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Atipamezole (MPV-1248, MPV1248, Antisedan) is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug.",212.29,"104054-27-5",{"v":42,"d":"42.00"},197.84,"<1","N/A","http://selleckchem.com/products/atipamezole.html","C14H16N2","Free Base","MPV-1248, MPV1248, MPV 1248, Antisedan","CCC1(CC2=C(C1)C=CC=C2)C3=CN=C[NH]3",3.012,1,1,2]
["S4651","Etoricoxib","c2","L4000-10","in 10mM DMSO","COX","Neuronal Signaling","Etoricoxib (Arcoxia, MK-663, MK-0663, Tauxib, Algix, Nucoxia) is a new COX-2 selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties.",358.84,"202409-33-4",{"v":71,"d":"71.00"},197.86,"<1","N/A","http://selleckchem.com/products/etoricoxib.html","C18H15ClN2O2S","free base","Arcoxia, MK-663, MK-0663, Tauxib, Algix, Nucoxia","CC1=NC=C(C=C1)C2=NC=C(Cl)C=C2C3=CC=C(C=C3)[S](C)(=O)=O",3.467,4,0,3]
["S4655","Sulpiride","d2","L4000-10","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Sulpiride (Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil) is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.",341.43,"15676-16-1",{"v":68,"d":"68.00"},199.16,"<1","N/A","http://selleckchem.com/products/sulpiride.html","C15H23N3O4S","free base","Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil","CCN1CCCC1CNC(=O)C2=C(OC)C=CC(=C2)[S](N)(=O)=O",0.704,4,2,6]
["S4656","Parecoxib","e2","L4000-10","in 10mM DMSO","COX","Neuronal Signaling","Parecoxib (SC-69124, Valus-P, Vorth-P) is a selective COX2 inhibitor.",370.42,"198470-84-7",{"v":74,"d":"74.00"},199.77,"<1","N/A","http://selleckchem.com/products/parecoxib.html","C19H18N2O4S","free base","SC-69124, Valus-P, Vorth-P","CCC(=O)N[S](=O)(=O)C1=CC=C(C=C1)C2=C(C)ON=C2C3=CC=CC=C3",3.256,5,1,5]
["S4657","Eslicarbazepine Acetate","f2","L4000-10","in 10mM DMSO","BACE,Sodium Channel","Neuronal Signaling","Eslicarbazepine Acetate (BIA 2093, Zebinix, Exalief, Stedesa, Aptiom), an antiepileptic drug, is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel.",296.32,"236395-14-5",{"v":59,"d":"59.00"},199.11,"<1","N/A","http://selleckchem.com/products/eslicarbazepine-acetate.html","C17H16N2O3","free base","BIA 2093, Zebinix, Exalief, Stedesa, Aptiom","CC(=O)OC1CC2=C(C=CC=C2)N(C(N)=O)C3=C1C=CC=C3",{"v":2.4,"d":"2.400"},3,1,2]
["S4660","Glycopyrrolate","g2","L4000-10","in 10mM DMSO","AChR","Neuronal Signaling","Glycopyrrolate (Glycopyrronium, Robinul, Gastrodyn) is a muscarinic antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with some anesthetics.",398.33,"596-51-0",{"v":65,"d":"65.00"},163.18,{"v":79,"d":"79.00"},198.33,"http://selleckchem.com/products/glycopyrrolate.html","C19H28NO3.Br","bromide","Glycopyrrolate bromide, Glycopyrronium bromide, Robinul, Gastrodyn","[Br-].C[N+]1(C)CCC(C1)OC(=O)C(O)(C2CCCC2)C3=CC=CC=C3",-0.961,2,0,5]
["S4661","Tiagabine hydrochloride","h2","L4000-10","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Tiagabine Hydrochloride (Gabitril, NO050328, NO328, TGB) is the hydrochloride salt form of tiagabine, a nipecotic acid derivative with anticonvulsant property. A selective gamma-aminobutyric acid (GABA) reuptake inhibitor.",412.01,"145821-59-6",{"v":82,"d":"82.00"},199.02,{"v":11,"d":"11.00"},{"v":26.7,"d":"26.70"},"http://selleckchem.com/products/tiagabine-hydrochloride.html","C20H25NO2S2.HCl","hydrochloride","Gabitril hydrochloride, NO050328 hydrochloride, NO328 hydrochloride, TGB hydrochloride","Cl.CC1=C(SC=C1)C(=CCCN2CCCC(C2)C(O)=O)C3=C(C)C=CS3",2.634,1,0,6]
["S4662","Atazanavir","a3","L4000-10","in 10mM DMSO","HIV Protease,P450 (e.g. CYP17),P-gp","Proteases","Atazanavir (Latazanavir, Zrivada, Reyataz, BMS-232632) is an azapeptide and HIV-protease inhibitor that is used in the treatment of HIV infections and AIDS in combination with other anti-HIV agents. Atazanavir is a substrate and inhibitor of cytochrome P450 isozyme 3A (CYP3A4) and an inhibitor and inducer of P-glycoprotein.",704.86,"198904-31-3",{"v":71,"d":"71.00"},100.73,"<1","N/A","http://selleckchem.com/products/atazanavir-reyataz.html","C38H52N6O7","free base","Latazanavir, Zrivada, Reyataz, BMS-232632","COC(=O)NC(C(=O)NC(CC1=CC=CC=C1)C(O)CN(CC2=CC=C(C=C2)C3=NC=CC=C3)NC(=O)C(NC(=O)OC)C(C)(C)C)C(C)(C)C",{"v":4.69,"d":"4.690"},7,5,18]
["S4667","Lidocaine hydrochloride","b3","L4000-10","in 10mM DMSO","EGFR","Angiogenesis","Lidocaine hydrochloride (Lidothesin, Lignocaine, Xyloneural) is an inhibitor of epidermal growth factor receptor (EGFR) and has antiproliferative effect on human tongue cancer cells. Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmia agent.",{"v":270.8,"d":"270.80"},"73-78-9",{"v":54,"d":"54.00"},199.41,{"v":54,"d":"54.00"},199.41,"http://selleckchem.com/products/lidocaine-hydrochloride.html","C14H22N2O.HCl","hydrochloride","Lidocaine HCL, Lidothesin, Lignocaine hydrochloride, Xyloneural","Cl.CCN(CC)CC(=O)NC1=C(C)C=CC=C1C",3.008,1,1,5]
["S4669","Benzocaine hydrochloride","c3","L4000-10","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Benzocaine hydrochloride (Ethyl 4-aminobenzoate, Ethyl p-aminobenzoate) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.",201.65,"23239-88-5",{"v":40,"d":"40.00"},198.36,"<1","N/A","http://selleckchem.com/products/benzocaine-hydrochloride.html","C9H11NO2.HCl","hydrochloride","Ethyl 4-aminobenzoate hydrochloride, Benzocaine HCl, Ethyl p-aminobenzoate hydrochloride","Cl.CCOC(=O)C1=CC=C(N)C=C1",1.669,2,1,3]
["S4672","Dimenhydrinate","d3","L4000-10","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Dimenhydrinate is an over-the-counter drug used to prevent nausea, vomiting, and dizziness caused by motion sickness.",469.96,"523-87-5",{"v":94,"d":"94.00"},200.02,"<1","N/A","http://www.selleck.cn/products/dimenhydrinate.html","C24H28ClN5O3","Free Base","N/A","CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.CN3C(=O)N(C)C4=C([NH]C(=N4)Cl)C3=O",3.955,4,1,6]
["S4679","Terazosin HCl","e3","L4000-10","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Terazosin (Hytrin, Zayasel, Terazosine, Flumarc, Fosfomic, Blavin) is a selective alpha-1 antagonist used for treatment of symptoms of an enlarged prostate (BPH). It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls.",423.89,"63074-08-8",{"v":84,"d":"84.00"},198.16,{"v":1,"d":"1.00"},2.36,"http://selleckchem.com/products/terazosin.html","C19H25N5O4.HCl","hydrochloride","Hytrin, Zayasel, Terazosine, Flumarc, Fosfomic, Blavin","Cl.COC1=CC2=C(C=C1OC)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N",1.762,6,1,4]
["S4682","Loxoprofen","f3","L4000-10","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Loxoprofen (Koloxo, Loxoprofene, Loxoprofeno) is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group.",{"v":246.3,"d":"246.30"},"68767-14-6",{"v":49,"d":"49.00"},198.94,"<1","N/A","http://selleckchem.com/products/loxoprofen.html","C15H18O3","free base","Koloxo, Loxoprofene, Loxoprofeno","CC(C(O)=O)C1=CC=C(CC2CCCC2=O)C=C1",2.936,2,0,4]
["S4686","Vitamin E","g3","L4000-10","in 10mM DMSO","COX,VEGFR","Neuronal Signaling","Vitamin E (D-alpha-Tocopherol) is a fat-soluble vitamin with potent antioxidant properties. It is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription.",430.71,"59-02-9","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/vitamin-e.html","C29H50O2","free base","Alpha-Tocopherol, D-alpha-Tocopherol, 5,7,8-Trimethyltocol|(+)-alpha-Tocopherol","CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=C(C)C(=C(C)C(=C2O1)C)O",{"v":10.44,"d":"10.440"},1,1,12]
["S4687","Rivastigmine","h3","L4000-10","in 10mM DMSO","AChR","Neuronal Signaling","Rivastigmine (SDZ-ENA 713, Exelon) is a cholinesterase inhibitor with IC50 of 5.5 μM. It inhibits acetylcholinesterase (IC50 = 4.15 µM) and butyrylcholinesterase (IC50 = 37 nM).",250.34,"123441-03-2","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/rivastigmine.html","C14H22N2O2","free base","SDZ-ENA 713, Exelon","CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C",2.599,2,0,5]
["S4693","Guanfacine Hydrochloride","a4","L4000-10","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Guanfacine Hydrochloride (Tenex, Intuniv) is a selective α2A-adrenoceptor agonist with anti-hypertensive effect.",282.55,"29110-48-3",{"v":56,"d":"56.00"},{"v":198.2,"d":"198.20"},{"v":30,"d":"30.00"},106.18,"http://selleckchem.com/products/guanfacine-hydrochloride.html","C9H9Cl2N3O.HCl","hydrochloride","Guanfacine, Tenex, Intuniv","Cl.NC(=N)NC(=O)CC1=C(Cl)C=CC=C1Cl",2.412,1,2,3]
["S4696","CarbinoxaMine Maleate","b4","L4000-10","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Carbinoxamine maleate is a histamine-H1 receptor blocking agent with antihistamine and anticholinergic properties.",406.86,"3505-38-2",{"v":81,"d":"81.00"},199.09,{"v":81,"d":"81.00"},199.09,"http://selleckchem.com/products/carbinoxamine-maleate.html","C16H19ClN2O.C4H4O4","maleate","N/A","CN(C)CCOC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.OC(=O)\\C=C/C(O)=O",0.224,4,0,8]
["S4707","Oleic Acid","c4","L4000-10","in 10mM DMSO","ATPase","Transmembrane Transporters","Oleic acid (Oleate, 9-Octadecenoic Acid, Elaidoic acid) is a fatty acid that occurs naturally in various animal and vegetable fats and oils. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent.  Oleic acid is an abundant monounsaturated fatty acid. Oleic acid is a Na+/K+ ATPase activator.",282.46,"112-80-1","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/oleic-acid.html","C18H34O2","Free Base","Oleate, 9-Octadecenoic Acid, Elaidoic acid","CCCCCCCC\\C=C/CCCCCCCC(O)=O",{"v":6.86,"d":"6.860"},1,0,15]
["S4714","(-)-Menthol","d4","L4000-10","in 10mM DMSO","TRP Channel","Transmembrane Transporters","(-)-Menthol is a levo isomer of menthol and used as a cooling agent that strongly activates TRPM8.",156.27,"2216-51-5",{"v":31,"d":"31.00"},198.37,{"v":16,"d":"16.00"},102.39,"http://selleckchem.com/products/-menthol.html","C10H20O","free base","L-Menthol, Levomenthol, Menthomenthol, Menthacamphor","CC(C)C1CCC(C)CC1O",2.779,0,1,1]
["S4715","Benzamide","e4","L4000-10","in 10mM DMSO","PARP","DNA Damage/DNA Repair","Benzamide, a derivative of benzoic acid, is an inhibitor of poly(ADP-ribose) polymerase with an IC50 of 3.3 μM.",121.14,"55-21-0",{"v":24,"d":"24.00"},198.12,"<1","N/A","http://selleckchem.com/products/benzamide.html","C7H7NO","free base","N/A","NC(=O)C1=CC=CC=C1",0.832,1,1,1]
["S4716","Evans Blue","f4","L4000-10","in 10mM DMSO","GluR","Neuronal Signaling","Evans Blue (Direct Blue 53,C.I.23860) is a potent inhibitor of the uptake of L-glutamate into synaptic vesicles, also an AMPA/kainate receptor antagonist.",960.81,"314-13-6",{"v":100,"d":"100.00"},104.08,{"v":100,"d":"100.00"},104.08,"http://selleckchem.com/products/evans-blue.html","C34H24N6O14S4.4Na","sodium salt","Direct Blue 53,C.I.23860","CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N=NC3=C(O)C4=C(N)C(=CC(=C4C=C3)[S](=O)(=O)O[Na])[S](=O)(=O)O[Na])C)N=NC5=C(O)C6=C(N)C(=CC(=C6C=C5)[S](=O)(=O)O[Na])[S](=O)(=O)O[Na]",6.593,8,4,13]
["S4717","Isatin","g4","L4000-10","in 10mM DMSO","MAO","Metabolism","Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor with an IC50 of 15 μM and more active against MAO-B than MAO-A.",147.13,"91-56-5",{"v":29,"d":"29.00"},{"v":197.1,"d":"197.10"},"<1","N/A","http://selleckchem.com/products/isatin.html","C8H5NO2","free base","2,3-Indolinedione","O=C1NC2=C(C=CC=C2)C1=O",{"v":0.67,"d":"0.670"},2,1,0]
["S4718","Acetylcholine iodide","h4","L4000-10","in 10mM DMSO","AChR","Neuronal Signaling","Acetylcholine iodide (Acetylcolina) is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.",273.11,"2260-50-6",{"v":54,"d":"54.00"},197.72,{"v":54,"d":"54.00"},197.72,"http://selleckchem.com/products/acetylcholine-iodide.html","C7H16NO2.I","iodide salt","Acetylcolina","[I-].CC(=O)OCC[N+](C)(C)C",-4.308,2,0,4]
["S4719","Kynurenic acid","a5","L4000-10","in 10mM DMSO","NMDAR","Neuronal Signaling","Kynurenic acid (Quinurenic acid, Kynurenate), a natural metabolite of tryptophan via the kynurenine pathway, is a broad-spectrum excitatory amino acid antagonist; It proved to be an antagonist at NMDA, kainate and AMPA\n\nreceptors.",189.17,"492-27-3",{"v":10,"d":"10.00"},52.86,"<1","N/A","http://selleckchem.com/products/kynurenic-acid.html","C10H7NO3","free base","Quinurenic acid, Kynurenate","OC(=O)C1=CC(=C2C=CC=CC2=N1)O",1.832,2,1,1]
["S4725","Benzenesulfonamide","b5","L4000-10","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Benzenesulfonamide (Benzenesulphonamide, Benzosulfonamide, Phenyl sulfonamide, Benzene sulfonamide) is an inhibitor of carbonic anhydrases.",157.19,"98-10-2",{"v":31,"d":"31.00"},197.21,"<1","N/A","http://selleckchem.com/products/benzenesulfonamide.html","C6H7NO2S","free base","Benzenesulphonamide, Benzosulfonamide, Phenyl sulfonamide, Benzene sulfonamide","N[S](=O)(=O)C1=CC=CC=C1",0.535,2,1,1]
["S4727","Cinnarizine","c5","L4000-10","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Cinnarizine (Stugeron, Dimitronal, Stutgin, Cinarizine) is a medication derivative of piperazine, and characterized as an antihistamine and a calcium channel blocker.",368.51,"298-57-7",{"v":73,"d":"73.00"},{"v":198.1,"d":"198.10"},"<1","N/A","http://selleckchem.com/products/cinnarizine.html","C26H28N2","free base","Stugeron, Dimitronal, Stutgin, Cinarizine","C1CN(CCN1C\\C=C\\C2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=CC=C4",5.524,0,0,6]
["S4731","Perphenazine","d5","L4000-10","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Perphenazine (Perphenazin, Trilafon, Etaperazine) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.",403.97,"58-39-9",{"v":74,"d":"74.00"},183.18,"<1","N/A","http://selleckchem.com/products/perphenazine.html","C21H26ClN3OS","free base","Perphenazin, Trilafon, Etaperazine","OCCN1CCN(CCCN2C3=CC=CC=C3SC4=C2C=C(Cl)C=C4)CC1",4.157,0,1,6]
["S4732","MPTP hydrochloride","e5","L4000-10","in 10mM DMSO","Apoptosis related,Dopamine Receptor","Neuronal Signaling","MPTP hydrochloride is a dopaminergic neurotoxin and cause selective destruction of dopaminergic neurons in animal models of parkinsonism. MPTP hydrochloride induces apoptosis.",209.72,"23007-85-4",{"v":20,"d":"20.00"},95.37,{"v":41,"d":"41.00"},{"v":195.5,"d":"195.50"},"http://selleckchem.com/products/mptp-hydrochloride.html","C12H15N.HCl","hydrochloride","N/A","Cl.CN1CCC(=CC1)C2=CC=CC=C2",2.788,0,0,1]
["S4733","Retigabine","f5","L4000-10","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Retigabine (D-23129) is a novel anticonvulsant with activity in a broad range of seizure models. The mechanism of action involves opening of neuronal K(V)7.2-7.5 (formerly KCNQ2-5) voltage-activated K(+) channels.",303.33,"150812-12-7",{"v":60,"d":"60.00"},{"v":197.8,"d":"197.80"},"<1","N/A","http://selleckchem.com/products/retigabine.html","C16H18FN3O2","free base","D-23129, N-(2-amino-4-[fluorobenzylamino]-phenyl) carbamic acid","CCOC(=O)NC1=CC=C(NCC2=CC=C(F)C=C2)C=C1N",2.793,2,3,6]
["S4734","Retigabine 2HCl","g5","L4000-10","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Retigabine 2HCl (D-23129) is a novel anticonvulsant with activity in a broad range of seizure models. The mechanism of action involves opening of neuronal K(V)7.2-7.5 (formerly KCNQ2-5) voltage-activated K(+) channels.",376.25,"150812-13-8",{"v":75,"d":"75.00"},199.34,{"v":75,"d":"75.00"},199.34,"http://selleckchem.com/products/retigabine-2hcl.html","C16H18FN3O2.2HCl","dihydrochloride","N-(2-amino-4-[fluorobenzylamino]-phenyl) carbamic acid (2HCl), D-23129 2HCl","Cl.Cl.CCOC(=O)NC1=CC=C(NCC2=CC=C(F)C=C2)C=C1N",3.557,2,3,6]
["S4739","Oxyresveratrol","h5","L4000-10","in 10mM DMSO","Tyrosinase","Proteases","Oxyresveratrol (Tetrahydroxystilbene, 2,3',4,5'-tetrahydroxystilbene), a naturally occurring compound particularly found in Morus alba L., exhibits a potent inhibitory effect on dopa oxidase activity of tyrosinase which catalyzes rate-limiting steps of melanin biosynthesis.",244.24,"29700-22-9",{"v":48,"d":"48.00"},196.53,{"v":1,"d":"1.00"},4.09,"http://selleckchem.com/products/oxyresveratrol.html","C14H12O4","free base","Tetrahydroxystilbene, 2,3',4,5'-tetrahydroxystilbene","OC1=CC=C(\\C=C\\C2=CC(=CC(=C2)O)O)C(=C1)O",2.848,0,4,2]
["S4746","(20S)-Protopanaxadiol","a6","L4000-10","in 10mM DMSO","P-gp","Transmembrane Transporters","20(S)-Protopanaxadiol (PPD, 20-Epiprotopanaxadiol), the main intestinal metabolite of ginsenosides, is one of the active ingredients in ginseng. 20(S)-Protopanaxadiol inhibits P-glycoprotein in multidrug resistant cancer cells.",460.73,"30636-90-9",{"v":92,"d":"92.00"},199.68,"<1","N/A","http://selleckchem.com/products/20s-protopanaxadiol.html","C30H52O3","free base","20-Epiprotopanaxadiol","CC(C)=CCCC(C)(O)C1CCC2(C)C1C(O)CC3C4(C)CCC(O)C(C)(C)C4CCC23C",5.789,0,2,4]
["S4748","Ondansetron Hydrochloride Dihydrate","b6","L4000-10","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Ondansetron is a highly specific and selective serotonin 5-HT3 receptor antagonist (Ki=6.16 nM), with low affinity for dopamine receptors.",365.85,"103639-04-9",{"v":73,"d":"73.00"},199.54,{"v":73,"d":"73.00"},199.54,"http://selleckchem.com/products/ondansetron-hcl.html","C18H19N3O.HCl.2H2O","hydrochloride","N/A","O.O.Cl.C[N]1C2=C(C(=O)C(CC2)C[N]3C=CN=C3C)C4=C1C=CC=C4",2.602,2,0,2]
["S4749","Citalopram HBr","c6","L4000-10","in 10mM DMSO","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Citalopram HBr (Nitalapram HBr, Prepram HBr, Bonitrile HBr, Lu 10-171 HBr), an antidepressant, is an orally administered selective serotonin reuptake inhibitor (SSRI) with IC50 of 1.8 nM.",{"v":405.3,"d":"405.30"},"59729-32-7",{"v":81,"d":"81.00"},199.85,{"v":81,"d":"81.00"},199.85,"http://selleckchem.com/products/citalopram-hbr.html","C20H21FN2O.HBr","hydrobromide","Nitalapram HBr, Prepram HBr, Bonitrile HBr, Lu 10-171 HBr","Br.CN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C3=CC=C(F)C=C3",4.212,1,0,5]
["S4751","Cisapride hydrate","d6","L4000-10","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Cisapride (Propulsid, Alimix, Propulsin, Enteropride, Kinestase) acts directly as a selective serotonin 5-HT4 receptor agonist with IC50 of 0.483 μM. And It also acts indirectly as a parasympathomimetic.",483.96,"260779-88-2",{"v":96,"d":"96.00"},198.36,"<1","N/A","https://www.selleckchem.com/products/cisapride-hydrate.html","C23H29ClFN3O4.H2O","hydrate","Propulsid, Alimix, Propulsin, Enteropride, Kinestase","O.COC1CN(CCCOC2=CC=C(F)C=C2)CCC1NC(=O)C3=CC(=C(N)C=C3OC)Cl",2.578,4,2,9]
["S4752","Corticosterone (NSC-9705)","e6","L4000-10","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Corticosterone (NSC-9705, 17-deoxycortisol, 11β,21-dihydroxyprogesterone), the major stress hormone, is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.",346.46,"50-22-6",{"v":69,"d":"69.00"},199.16,"<1","N/A","http://selleckchem.com/products/corticosterone.html","C21H30O4","free base","17-deoxycortisol, 11β,21-dihydroxyprogesterone","CC12CC(O)C3C(CCC4=CC(=O)CCC34C)C1CCC2C(=O)CO",2.019,2,2,2]
["S4760","(2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD)","f6","L4000-10","in 10mM DMSO","Beta Amyloid,Hydrotropic Agents","Neuronal Signaling","(2-Hydroxypropyl)-β-cyclodextrin (HP-β-CD, HP-β-cyclodextrin, Hydroxypropyl betadex, Hydroxypropyl-β-cyclodextrin), a well-known sugar used in drug delivery, genetic vector, environmental protection and treatment of Niemann-Pick disease type C1 (NPC1), is an inhibitor of amyloid-β aggregation.",1541.54,"128446-35-5",{"v":100,"d":"100.00"},64.87,{"v":100,"d":"100.00"},64.87,"http://selleckchem.com/products/2-hydroxypropyl-beta-cyclodextrin-hp-beta-cd.html","C63H112O42","free base","HP-β-cyclodextrin, Hydroxypropyl betadex, Hydroxypropyl-β-cyclodextrin","CC(O)COCC1OC2OC3C(O)C(O)C(OC3COCC(C)O)OC4C(O)C(O)C(OC4COCC(C)O)OC5C(O)C(O)C(OC5COCC(C)O)OC6C(O)C(O)C(OC6COCC(C)O)OC7C(O)C(O)C(OC7COCC(C)O)OC8C(O)C(O)C(OC8COCC(C)O)OC1C(O)C2O",-10.503,21,21,28]
["S4765","Syringaldehyde","g6","L4000-10","in 10mM DMSO","COX","Immunology & Inflammation","Syringaldehyde (Syringic aldehyde) is an organic compound that occurs naturally in trace amounts. It possesses worthy bioactive properties and is, therefore, used in pharmaceuticals, food, cosmetics, textiles, pulp and paper industries, and even in biological control applications.  Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis. Syringaldehyde moderately inhibits COX-2 activity with an IC50 of 3.5 μg/mL[2]. Anti-hyperglycemic and anti-inflammatory activities.",182.17,"134-96-3",{"v":36,"d":"36.00"},197.62,"N/A","N/A","http://selleckchem.com/products/syringaldehyde.html","C9H10O4","free base","Syringic aldehyde","COC1=C(O)C(=CC(=C1)C=O)OC",1.314,3,1,3]
["S4767","7-Hydroxy-3,4-dihydrocarbostyril","h6","L4000-10","in 10mM DMSO","Others","Others","7-Hydroxy-3,4-dihydrocarbostyril is used as the materials for the organic synthesis intermediates.",163.17,"22246-18-0",{"v":32,"d":"32.00"},196.11,"N/A","N/A","http://selleckchem.com/products/7-hydroxy-3-4-dihydrocarbostyril.html","C9H9NO2","free base","N/A","OC1=CC2=C(CCC(=O)N2)C=C1",1.033,1,2,0]
["S4769","L-5-Hydroxytryptophan","a7","L4000-10","in 10mM DMSO","Others","Others","5-Hydroxytryptophan (5-HTP, L-oxitriptan), also known as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin.",220.22,"4350-09-8",{"v":16,"d":"16.00"},72.65,"N/A","N/A","http://selleckchem.com/products/l-5-hydroxytryptophan.html","C11H12N2O3","free base","L-oxitriptan","NC(CC1=C[NH]C2=CC=C(O)C=C12)C(O)=O",-1.554,1,3,3]
["S4772","alpha-Asarone","b7","L4000-10","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Alpha (α)-asarone (trans-Asarone) is one of the main pharmacologically active compounds present in Acorus calamus Linn (Acoraceae), Acorus tatarinowii Schott (Acoraceae), and Acorus gramineus Solander. It has anticonvulsant, neuroprotective, anxiolytic and nootropic effects.",208.25,"2883-98-9",{"v":41,"d":"41.00"},196.88,"N/A","N/A","http://selleckchem.com/products/alpha-asarone.html","C12H16O3","free base","trans-Asarone","COC1=CC(=C(\\C=C\\C)C=C1OC)OC",2.734,3,0,4]
["S4774","Xanthurenic Acid","c7","L4000-10","in 10mM DMSO","GluR","Neuronal Signaling","Xanthurenic acid (xanthurenate, 8-Hydroxykynurenic acid, 4,8-Dihydroxyquinaldic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGlu2 and mGlu3).",205.17,"59-00-7",{"v":7,"d":"7.00"},34.12,"N/A","N/A","http://selleckchem.com/products/xanthurenic-acid.html","C10H7NO4","free base","xanthurenate, 8-Hydroxykynurenic acid, 4,8-Dihydroxyquinaldic acid","OC(=O)C1=CC(=C2C=CC=C(O)C2=N1)O",{"v":1.59,"d":"1.590"},2,2,1]
["S4775","Cortodoxone","d7","L4000-10","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Cortodoxone (11-Deoxycortisol, cortexolone, 11-Desoxycortisol, 17α,21-dihydroxyprogesterone), also known as 11-Deoxycortisol, is a glucocorticoid steroid hormone.",346.46,"152-58-9",{"v":69,"d":"69.00"},199.16,"N/A","N/A","http://selleckchem.com/products/cortodoxone.html","C21H30O4","free base","11-Deoxycortisol, cortexolone, 11-Desoxycortisol, 17α,21-dihydroxyprogesterone","CC12CCC(=O)C=C1CCC3C2CCC4(C)C3CCC4(O)C(=O)CO",2.452,2,1,2]
["S4787","Methyl syringate","e7","L4000-10","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Methyl syringate (Syringic Acid Methyl Ester), a plant phenolic compound, is a specific and selective TRPA1 agonist.",{"v":212.2,"d":"212.20"},"884-35-5",{"v":42,"d":"42.00"},197.93,"N/A","N/A","http://selleckchem.com/products/methyl-syringate.html","C10H12O5","free base","Syringic Acid Methyl Ester","COC(=O)C1=CC(=C(O)C(=C1)OC)OC",{"v":0,"d":"0.000"},0,0,0]
["S4797","Nicergoline","f7","L4000-10","in 10mM DMSO","Adrenergic Receptor","Endocrinology & Hormones","Nicergoline is an ergot derivative used to treat senile dementia and other disorders with vascular origins. It has a selective alpha-1A adrenergic receptor blocking property and also other additional mechanisms of actions.",484.39,"27848-84-6",{"v":22,"d":"22.00"},45.42,"N/A","N/A","http://selleckchem.com/products/nicergoline.html","C24H26BrN3O3","free base","N/A","COC12CC(COC(=O)C3=CN=CC(=C3)Br)CN(C)C1CC4=C[N](C)C5=CC=CC2=C45",{"v":0,"d":"0.000"},0,0,0]
["S4804","1-Naphthyl acetate","g7","L4000-10","in 10mM DMSO","AChR","Neuronal Signaling","1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages. 1-Naphthyl acetate is  a potent chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity.",186.21,"830-81-9",{"v":37,"d":"37.00"},{"v":198.7,"d":"198.70"},"N/A","N/A","http://selleckchem.com/products/1-naphthyl-acetate.html","C12H10O2","free base","N/A","CC(=O)OC1=C2C=CC=CC2=CC=C1",{"v":0,"d":"0.000"},0,0,0]
["S4809","3-Indolepropionic acid","h7","L4000-10","in 10mM DMSO","Others","Others","3-Indolepropionic acid (IPA, indole-3-propionic acid), a gut microbial metabolite, is a potent neuroprotective antioxidant and plant auxin.",189.21,"830-96-6",{"v":37,"d":"37.00"},195.55,"N/A","N/A","http://selleckchem.com/products/3-indolepropionic-acid.html","C11H11NO2","free base","indole-3-propionic acid, Indolepropionic acid","OC(=O)CCC1=C[NH]C2=C1C=CC=C2",{"v":0,"d":"0.000"},0,0,0]
["S4817","Atenolol","a8","L4000-10","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Atenolol (Tenormin, Normiten, Blokium) is a selective β1 receptor antagonist with log Kd values of −6.66±0.05, −5.99±0.14, −4.11±0.07 for binding to the human β1-, β2- and β3-adrenoceptors.",266.34,"29122-68-7",{"v":53,"d":"53.00"},198.99,{"v":35,"d":"35.00"},131.41,"http://selleckchem.com/products/atenolol.html","C14H22N2O3","free base","Tenormin, Normiten, Blokium","CC(C)NCC(O)COC1=CC=C(CC(N)=O)C=C1",0.669,2,3,8]
["S4832","Tolmetin","b8","L4000-10","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Tolmetin (Tolectin) is a nonsteroidal anti-inflammatory drug of the heterocyclic acetic acid derivative class and also exhibits analgesic and antipyretic activity.",257.28,"26171-23-3",{"v":51,"d":"51.00"},198.23,"N/A","N/A","http://selleckchem.com/products/tolmetin.html","C15H15NO3","free base","Tolectin","C[N]1C(=CC=C1C(=O)C2=CC=C(C)C=C2)CC(O)=O",3.267,2,0,4]
["S4834","Propantheline bromide","c8","L4000-10","in 10mM DMSO","AChR","Neuronal Signaling","Propantheline bromide (Pro-Banthine, Neometantyl, Neopepulsan) is a muscarinic antagonist used to treat gastrointestinal conditions associated with intestinal spasm and to decrease secretions during anesthesia.",448.39,"50-34-0",{"v":89,"d":"89.00"},198.49,"N/A","N/A","http://selleckchem.com/products/propantheline-bromide.html","C23H30NO3.Br","bromide","Pro-Banthine, Neometantyl, Neopepulsan","[Br-].CC(C)[N+](C)(CCOC(=O)C1C2=C(OC3=CC=CC=C13)C=CC=C2)C(C)C",0.763,3,0,7]
["S4837","Ibudilast","d8","L4000-10","in 10mM DMSO","PDE","Metabolism","Ibudilast (KC-404, AV411, MN166) is a relatively non-selective phosphodiesterase inhibitor with anti-inflammatory and neuroprotective activities.",230.31,"50847-11-5",{"v":46,"d":"46.00"},199.73,{"v":30,"d":"30.00"},130.26,"http://selleckchem.com/products/Ibudilast.html","C14H18N2O","free base","KC-404, AV411, MN166","CC(C)C(=O)C1=C2C=CC=C[N]2N=C1C(C)C",3.339,2,0,3]
["S4838","Acotiamide hydrochloride","e8","L4000-10","in 10mM DMSO","AChR","Neuronal Signaling","Acotiamide Hydrochloride (YM-443, Z-338) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. It is a new orally active selective acetylcholinesterase inhibitor.",541.06,"773092-05-0",{"v":100,"d":"100.00"},184.82,{"v":5,"d":"5.00"},9.24,"http://selleckchem.com/products/acotiamide-hydrochloride.html","C21H30N4O5S.HCl.3H2O","hydrochloride trihydrate","YM-443 HCl, Z-338 HCl","O.O.O.Cl.COC1=CC(=C(C=C1OC)C(=O)NC2=NC(=CS2)C(=O)NCCN(C(C)C)C(C)C)O",2.325,5,3,10]
["S4839","Mosapride","f8","L4000-10","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.",421.89,"112885-41-3",{"v":84,"d":"84.00"},{"v":199.1,"d":"199.10"},"N/A","N/A","http://selleckchem.com/products/mosapride.html","C21H25ClFN3O3","Benzamide","N/A","CCOC1=CC(=C(Cl)C=C1C(=O)NCC2CN(CCO2)CC3=CC=C(F)C=C3)N",2.932,3,2,7]
["S4849","Levocetirizine Dihydrochloride","g8","L4000-10","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Levocetirizine (Xyzal, (-)-Cetirizine) is the active R-enantiomer of cetirizine and represents a new second-generation histamine H1 antagonist.",461.81,"130018-87-0",{"v":92,"d":"92.00"},199.22,{"v":92,"d":"92.00"},199.22,"http://selleckchem.com/products/levocetirizine-dihydrochloride.html","C21H25ClN2O3.2HCl","dihydrochloride","Xyzal Dihydrochloride, (-)-Cetirizine Dihydrochloride","Cl.Cl.OC(=O)COCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3",1.217,2,0,8]
["S4856","Iproniazid","h8","L4000-10","in 10mM DMSO","MAO","Metabolism","Iproniazid (Marsilid, Iprazid) is a non-selective, irreversible monoamine oxidase (MAO) inhibitor (MAOI) that is used as an antidepressive agent.",179.22,"54-92-2",{"v":35,"d":"35.00"},195.29,{"v":35,"d":"35.00"},195.29,"http://selleckchem.com/products/Iproniazid.html","C9H13N3O","free base","Marsilid, Iprazid","CC(C)NNC(=O)C1=CC=NC=C1",0.121,2,2,3]
["S4889","Perospirone hydrochloride","a9","L4000-10","in 10mM DMSO","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Perospirone (SM-9018) is an atypical or second-generation antipsychotic of the azapirone family that antagonizes serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist.",463.04,"129273-38-7",{"v":92,"d":"92.00"},198.69,"N/A","N/A","http://selleckchem.com/products/perospirone-hydrochloride.html","C23H30N4O2S.HCl","hydrochloride","SM-9018 hydrochloride","Cl.O=C1C2CCCCC2C(=O)N1CCCCN3CCN(CC3)C4=NSC5=C4C=CC=C5",4.423,3,0,6]
["S4892","Phenibut","b9","L4000-10","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Phenibut (Aminophenylbutyric acid, Fenibut, Phenigam, Phenybut, PhGABA, β-Phenyl-γ-aminobutyric acid, β-Phenyl-GABA), a GABA analogue, is a central nervous system depressant with anxiolytic and sedative effects.",179.22,"1078-21-3",{"v":35,"d":"35.00"},195.29,"N/A","N/A","http://selleckchem.com/products/phenibut.html","C10H13NO2","free base","Aminophenylbutyric acid, Fenibut, Fenigam, Phenigam, Phenybut, PhGABA, β-Phenyl-γ-aminobutyric acid, β-Phenyl-GABA","NCC(CC(O)=O)C1=CC=CC=C1",-1.724,1,1,4]
["S4902","QNZ (EVP4593)","c9","L4000-10","in 10mM DMSO","NF-κB,TNF-alpha","NF-κB","QNZ (EVP4593) shows potent inhibitory activity toward both NF-κB activation and TNF-α production with IC50 of 11 nM and 7 nM in Jurkat T cells, respectively.",356.42,"545380-34-5",{"v":5,"d":"5.00"},14.03,"<1","N/A","http://selleckchem.com/products/qnz-evp4593.html","C22H20N4O","free base","N/A","NC1=CC2=C(NCCC3=CC=C(OC4=CC=CC=C4)C=C3)N=CN=C2C=C1",4.454,3,2,6]
["S4904","JZL184","d9","L4000-10","in 10mM DMSO","Lipase","Metabolism","JZL 184 is the first selective inhibitor of monoacylglycerol lipase (MAGL) with IC50 of 8 nM.",520.49,"1101854-58-3",{"v":100,"d":"100.00"},192.13,"<1","N/A","http://selleckchem.com/products/jzl184.html","C27H24N2O9","free base","N/A","OC(C1CCN(CC1)C(=O)OC2=CC=C(C=C2)[N+]([O-])=O)(C3=CC=C4OCOC4=C3)C5=CC=C6OCOC6=C5",4.292,6,0,6]
["S4926","(R)-Nepicastat HCl","e9","L4000-10","in 10mM DMSO","Hydroxylase","Metabolism","(R)-Nepicastat HCl (RS-25560-198), the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.",331.81,"195881-94-8",{"v":66,"d":"66.00"},198.91,"<1","N/A","http://selleckchem.com/products/r-nepicastat-hcl.html","C14H15F2N3S.HCl","Hydrochloride","RS-25560-198 HCl","Cl.NCC1=CNC(=S)N1C2CCC3=C(F)C=C(F)C=C3C2",3.008,0,2,2]
["S4931","Propiverine hydrochloride","f9","L4000-10","in 10mM DMSO","AChR,Calcium Channel","Transmembrane Transporters","Propiverine is an anticholinergic drug used for the treatment of overactive bladder and urinary incontinence. Propiverine is a muscarinic receptor antagonist possessing additional properties, i.e., block of L-type Ca2+ channels.",403.94,"54556-98-8",{"v":80,"d":"80.00"},198.05,"N/A","N/A","http://selleckchem.com/products/propiverine-hydrochloride.html","C23H29NO3.ClH","HCl","N/A","Cl.CCCOC(C(=O)OC1CCN(C)CC1)(C2=CC=CC=C2)C3=CC=CC=C3",4.388,3,0,8]
["S4932","Proxyphylline","g9","L4000-10","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","Proxyphylline (Monophylline, Spasmolysin) is a derivative of theophylline which is used as a bronchodilator and for its cardiovascular properties. It selectively antagonizes A1 adenosine receptors (Ki = 82 nM for bovine brain) versus A2 adenosine receptors (Ki = 850 µM for platelets).",238.24,"603-00-9",{"v":47,"d":"47.00"},197.28,"N/A","N/A","http://selleckchem.com/products/proxyphylline.html","C10H14N4O3","free base","Monophylline, Spasmolysin","CC(O)C[N]1C=NC2=C1C(=O)N(C)C(=O)N2C",-0.262,3,1,2]
["S4957","Linalool","h9","L4000-10","in 10mM DMSO","NMDAR","Neuronal Signaling","Linalool (Phantol), a monoterpene compound commonly found as major component of essential oils of several aromatic species, is a competitive antagonist of NMDA receptors.",154.25,"78-70-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/linalool.html","C10H18O","free base","Phantol","CC(C)=CCCC(C)(O)C=C",2.735,0,0,4]
["S4961","3,4,5-Trimethoxycinnamic acid","a10","L4000-10","in 10mM DMSO","GABA Receptor","Neuronal Signaling","3,4,5-Trimethoxycinnamic acid (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GABAA/BZ receptor complex.",238.24,"90-50-6",{"v":47,"d":"47.00"},197.28,"N/A","N/A","http://selleckchem.com/products/trimethoxycinnamic-acid.html","C12H14O5","free base","N/A","COC1=C(OC)C(=CC(=C1)/C=C/C(O)=O)OC",1.878,4,0,5]
["S4969","Tropine","b10","L4000-10","in 10mM DMSO","Others","Others","Tropine (Pseudotropine, 3alpha-Tropanol) is a naturally occurring tropane alkaloid that serves as an intermediate in the synthesis of a variety of bioactive alkaloids, many of which have potent neurological actions.",141.21,"120-29-6",{"v":28,"d":"28.00"},198.29,"N/A","N/A","http://selleckchem.com/products/tropine.html","C8H15NO","free base","Pseudotropine, 3alpha-Tropanol","CN1C2CCC1CC(O)C2",0.271,0,1,0]
["S4970","Nerol","c10","L4000-10","in 10mM DMSO","Fungal,ROS","Apoptosis","Nerol (Cis-Geraniol, Neryl alcohol) is a monoterpene found in many essential oils such as lemongrass and hops. Nerol has antifungal activity, Nerol can trigger mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS leading to apoptosis.",154.25,"106-25-2","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/nerol.html","C10H18O","free base","Cis-Geraniol, Neryl alcohol","CC(C)=CCC\\C(C)=C/CO",2.934,0,1,4]
["S4973","Iminostilbene","d10","L4000-10","in 10mM DMSO","Others","Others","Iminostilbene (2,3,6,7-Dibenzazepine) is a chemical precursor of carbamazepine which is used primarily in the treatment of epilepsy and neuropathic pain.",193.24,"256-96-2",{"v":38,"d":"38.00"},196.65,"N/A","N/A","http://selleckchem.com/products/iminostilbene.html","C14H11N","free base","2,3,6,7-Dibenzazepine","N1C2=C(C=CC=C2)C=CC3=CC=CC=C13",3.536,0,1,0]
["S4975","Fimasartan","e10","L4000-10","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Fimasartan (Kanarb) is a non-peptide angiotensin II receptor antagonist (ARB) with noncompetitive, insurmountable binding with the AT1 receptor. It is used for the treatment of hypertension and heart failure.",501.65,"247257-48-3",{"v":100,"d":"100.00"},199.34,"N/A","N/A","http://selleckchem.com/products/fimasartan.html","C27H31N7OS","free base","Kanarb","CCCCC1=NC(=C(CC(=S)N(C)C)C(=O)N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=N[NH]4)C",4.515,5,1,10]
["S4977","Efonidipine","f10","L4000-10","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Efonidipine (NZ-105) is an L- and T-type calcium channel blocker leading to vasodilation and decreased automaticity of the heart. It also suppresses aldosterone secretion from the adrenal.",631.66,"111011-63-3",{"v":100,"d":"100.00"},158.31,"N/A","N/A","http://selleckchem.com/products/efonidipine.html","C34H38N3O7P","free base","NZ-105","CC1=C(C(C2=CC(=CC=C2)[N+]([O-])=O)C(=C(C)N1)[P]3(=O)OCC(C)(C)CO3)C(=O)OCCN(CC4=CC=CC=C4)C5=CC=CC=C5",4.956,4,1,11]
["S4989","AOA hemihydrochloride","g10","L4000-10","in 10mM DMSO","Transferase","Metabolism","AOA hemihydrochloride (Aminooxyacetic acid, Carboxymethoxylamine, AOAA, Aminooxyacetate hemihydrochloride) is an inhibitor of aminobutyrate aminotransferase involved in amino acid and polyamine metabolism. AOA hemihydrochloride is also a CBS (cystathionine β-synthase) inhibitor.",{"v":109.3,"d":"109.30"},"2921-14-4",{"v":21,"d":"21.00"},192.13,"N/A","N/A","http://selleckchem.com/products/aminooxyacetic-acid-hemihydrochloride.html","C2H5NO3.1/2HCl","hemihydrochloride","Aminooxyacetic acid hemihydrochloride, Carboxymethoxylamine hemihydrochloride, AOAA hemihydrochloride, Aminooxyacetate hemihydrochloride","NOCC(O)=O",-0.432,2,1,2]
["S4991","Valpromide","h10","L4000-10","in 10mM DMSO","Epoxide Hydrolase","Metabolism","Valpromide (Depamide, Dipropylacetamide, 2-propylpentanamide) is an antiepileptic drug, derivative of Valproic acid (VPA), used as a mood-stabilizer in bipolar disorder. Valpromide inhibits both viral and cellular gene expression. Valpromide is a human epoxide hydrolase inhibitor.",143.23,"2430-27-5",{"v":28,"d":"28.00"},195.49,"N/A","N/A","http://selleckchem.com/products/valpromide.html","C8H17NO","free base","Depamide, Dipropylacetamide, 2-propylpentanamide","CCCC(CCC)C(N)=O",2.122,1,1,5]
["S4992","Nanofin","a11","L4000-10","in 10mM DMSO","AChR","Neuronal Signaling","Nanofin (2,6-Dimethylpiperidine, Lupetidine, Naniopinum) is a ganglion blocker alkaloid having nicotinic acetylcholine receptor antagonist action. It has antihypertensive effect used for mild to moderate hypertension.",{"v":113.2,"d":"113.20"},"504-03-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/nanofin.html","C7H15N","Piperidines","2,6-Dimethylpiperidine, Lupetidine, Naniopinum","CC1CCCC(C)N1",1.456,0,1,0]
["S4994","Methylcobalamin","b11","L4000-10","in 10mM DMSO","Vitamin","Metabolism","Methylcobalamin (Mecobalamin, Vancomin, Methycobal, Cobametin) is one active form of vitamin B12 which can directly participate in homocysteine metabolism. It is used to treat some nutritional diseases and other diseases in clinic, such as Alzheimer's disease and rheumatoid arthritis.",1344.38,"13422-55-4",{"v":100,"d":"100.00"},74.38,"N/A","N/A","http://selleckchem.com/products/methylcobalamin.html","C63H91CoN13O14P","inner salt","Mecobalamin, Vancomin, Methycobal, Cobametin","C[Co+]N1\\C2=C(C)/C3=N\\C(=C/C4=NC(=C(C)/C5=NC(C(CC(N)=O)C5(C)CCC(=O)NCC(C)O[P]([O-])(=O)OC6C(O)C(OC6CO)[N]7C=NC8=C7C=C(C)C(=C8)C)C1(C)C(C)(CC(N)=O)C2CCC(N)=O)\\C(CCC(N)=O)C4(C)C)C(CCC(N)=O)C3(C)CC(N)=O",-0.736,14,9,27]
["S5010","Indometacin Sodium","c11","L4000-10","in 10mM DMSO","COX","Immunology & Inflammation","Indometacin Sodium (Indomethacin Sodium) is the sodium salt of indomethacin, which is a non-selective, reversible, and competitive inhibitor of cyclooxygenases 1 and 2 with anti-inflammatory, analgesic-antipyretic and tocolytic effects.",433.82,"74252-25-8",{"v":87,"d":"87.00"},200.55,{"v":-1,"d":"-1.00"},-2.31,"https://www.selleckchem.com/products/indometacin-sodium.html","C19H21ClNNaO7","sodium salt trihydrate","Indomethacin Sodium","O.O.O.COC1=CC2=C(C=C1)[N](C(=C2CC(=O)O[Na])C)C(=O)C3=CC=C(Cl)C=C3",3.705,4,0,5]
["S5019","Indobufen","d11","L4000-10","in 10mM DMSO","COX","Immunology & Inflammation","Indobufen (Ibustrin, K 3920) is a reversible platelet aggregation inhibitor. Indobufen is a reversible inhibitor of platelet cyclooxygenase (Cox) activity and suppresses thromboxane synthesis.",295.33,"63610-08-2",{"v":59,"d":"59.00"},199.78,"N/A","N/A","http://selleckchem.com/products/indobufen.html","C18H17NO3","free base","Ibustrin, K 3920","CCC(C(O)=O)C1=CC=C(C=C1)N2CC3=C(C=CC=C3)C2=O",3.157,2,0,4]
["S5023","Nadolol","e11","L4000-10","in 10mM DMSO","Adrenergic Receptor","Endocrinology & Hormones","Nadolol (Corgard, Solgol, Anabet, SQ11725) is a non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities.",{"v":309.4,"d":"309.40"},"42200-33-9",{"v":61,"d":"61.00"},197.16,"N/A","N/A","http://selleckchem.com/products/nadolol.html","C17H27NO4","free base","Corgard, Solgol, Anabet, SQ11725","CC(C)(C)NCC(O)COC1=CC=CC2=C1CC(O)C(O)C2",1.146,1,4,6]
["S5032","Mephenesin","f11","L4000-10","in 10mM DMSO","NMDAR","Neuronal Signaling","Mephenesin (Decontractyl, Cresoxydiol, Memphenesin, Mephedan) is centrally acting muscle relaxant, a topical analgesic and may be an NMDA receptor antagonist.",182.22,"59-47-2",{"v":36,"d":"36.00"},197.56,{"v":30,"d":"30.00"},164.64,"http://selleckchem.com/products/mephenesin.html","C10H14O3","free base","Decontractyl, Cresoxydiol, Memphenesin, Mephedan","CC1=C(OCC(O)CO)C=CC=C1",1.249,1,2,4]
["S5034","Melitracen hydrochloride","g11","L4000-10","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Melitracen hydrochloride (Thymeol) is a potential dopamine D1/2 receptor antagonist which has antidepressant properties.",327.89,"10563-70-9",{"v":65,"d":"65.00"},198.24,{"v":65,"d":"65.00"},198.24,"http://selleckchem.com/products/melitracen-hydrochloride.html","C21H25N.HCl","hydrochloride","Thymeol hydrochloride","Cl.CN(C)CC[CH]=[C]1C2=C(C=CC=C2)[C](C)(C)C3=C1C=CC=C3",5.155,0,0,3]
["S5038","Valethamate Bromide","h11","L4000-10","in 10mM DMSO","Others","Others","Valethamate bromide (Ediposin) is an alkylbenzene which is useful for facilitating cervical ripening, dilatation and thereby decreasing the duration of labor.",386.37,"90-22-2",{"v":77,"d":"77.00"},199.29,{"v":77,"d":"77.00"},199.29,"http://www.selleckchem.com/products/valethamate-bromide.html","C19H32BrNO2","Bromide","Ediposin","[Br-].CCC(C)C(C(=O)OCC[N+](C)(CC)CC)C1=CC=CC=C1",{"v":0.41,"d":"0.410"},2,0,10]
["S5042","Bevantolol hydrochloride","a2","L4000-11","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Bevantolol hydrochloride (NC-1400) is a cardioselective, beta adrenoceptor antagonist, devoid of intrinsic β sympathomimetic activity and with weak membrane-stabilizing and local anesthetic properties.",381.89,"42864-78-8",{"v":76,"d":"76.00"},199.01,{"v":52,"d":"52.00"},136.16,"http://selleckchem.com/products/bevantolol-hydrochloride.html","C20H27NO4.HCl","hydrochloride","NC-1400 hydrochloride","Cl.COC1=C(OC)C=C(CCNCC(O)COC2=CC=CC(=C2)C)C=C1",3.645,3,2,10]
["S5045","Nomilin","b2","L4000-11","in 10mM DMSO","Apoptosis related","MAPK","Nomilin is a triterpenoid present in common edible citrus fruits with putative anticancer properties.",514.56,"1063-77-0",{"v":100,"d":"100.00"},194.34,"<1","N/A","http://selleckchem.com/products/nomilin.html","C28H34O9","free base","N/A","CC(=O)OC1CC(=O)OC(C)(C)C2CC(=O)C3(C)C(CCC4(C)C(OC(=O)C5OC345)C6=COC=C6)C12C",2.151,9,0,3]
["S5049","Thiocolchicoside","c2","L4000-11","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Thiocolchicoside (Thiocolchicine 2-glucoside analog, Coltramyl) is a natural occuring glycoside originated from the flower seeds of superba gloriosa with anti-inflammatory and analgesic properties as well as pronounced convulsant activity. It is also an antagonist of GABAA receptor.",563.62,"602-41-5",{"v":100,"d":"100.00"},177.42,{"v":100,"d":"100.00"},177.42,"http://selleckchem.com/products/thiocolchicoside.html","C27H33NO10S","Phenolic glycosides","Thiocolchicine 2-glucoside analog, Coltramyl","COC1=C(OC)C2=C(CCC(NC(C)=O)C3=CC(=O)C(=CC=C23)SC)C=C1OC4OC(CO)C(O)C(O)C4O",0.446,6,5,7]
["S5052","Granisetron","d2","L4000-11","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Granisetron (Sancuso, Kevatril, Granisetronum, Sustol) is a serotonin receptor (5HT-3 selective) antagonist that is used as an antiemetic and antinauseant for cancer chemotherapy.",312.41,"109889-09-0",{"v":11,"d":"11.00"},35.21,"N/A","N/A","http://selleckchem.com/products/granisetron.html","C18H24N4O","Serotonin 5-HT3 receptor","Sancuso, Kevatril, Granisetronum, Sustol","CN1C2CCCC1CC(C2)NC(=O)C3=N[N](C)C4=C3C=CC=C4",2.401,2,1,2]
["S5060","Metadoxine","e2","L4000-11","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Metadoxine (Metadoxil, Metasin, pyridoxine-pyrrolidone carboxylat), also known as pyridoxine-pyrrolidone carboxylate, is a drug used to treat chronic and acute alcohol intoxication.  Metadoxine is a novel 5-HT2B receptor antagonist with a possible therapeutic role in treating ADHD.",298.29,"74536-44-0",{"v":59,"d":"59.00"},197.79,"N/A","N/A","http://selleckchem.com/products/metadoxine.html","C8H11NO3.C5H7NO3","salt","Metadoxil, Metasin, pyridoxine-pyrrolidone carboxylat","CC1=C(O)C(=C(CO)C=N1)CO.OC(=O)C2CCC(=O)N2",-1.243,3,4,3]
["S5066","Pramipexole dihydrochloride","f2","L4000-11","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Pramipexole dihydrochloride (SND919) is a dopamine agonist of the non-ergoline class indicated for treating Parkinson's disease (PD) and restless legs syndrome (RLS) with Ki values of 3.9 nM, 2.2 nM, 0.5 nM and 5.1 nM for D2S receptor, D2L receptor, D3 receptor and D4 receptor.",284.25,"104632-25-9",{"v":56,"d":"56.00"},197.01,"N/A","N/A","http://selleckchem.com/products/pramipexole-dihydrochloride.html","C10H17N3S.2HCl","dihydrochloride","SND919","Cl.Cl.CCCNC1CCC2=C(C1)SC(=N2)N",2.147,1,2,3]
["S5067","Losartan","g2","L4000-11","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Losartan(DuP-753) is a selective, orally administered, nonpeptide blocker of angiotensin II type 1 (AT1) receptor used to treat high blood pressure, diabetic kidney disease, heart failure, and left ventricular enlargement.",422.91,"114798-26-4",{"v":84,"d":"84.00"},198.62,{"v":-1,"d":"-1.00"},-2.36,"https://www.selleckchem.com/products/losartan.html","C22H23ClN6O","free base","DuP-753","CCCCC1=NC(=C(CO)[N]1CC2=CC=C(C=C2)C3=C(C=CC=C3)C4=NN=N[NH]4)Cl",4.241,4,2,8]
["S5071","Duloxetine","h2","L4000-11","in 10mM DMSO","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Duloxetine (LY-248686) is a potent inhibitor of serotonin (5-hydroxytryptamine, 5-HT) and noradrenaline (NE) uptake in vitro and in vivo and is 3- to 5-times more effective at inhibiting 5-HT uptake.",297.41,"116539-59-4","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/duloxetine.html","C18H19NOS","free base","LY-248686","CNCCC(OC1=CC=CC2=CC=CC=C12)C3=CC=CS3",3.846,1,1,6]
["S5073","Donepezil","a3","L4000-11","in 10mM DMSO","AChR","Neuronal Signaling","Donepezil (Aricept, Donepezilo) is a piperidine based, potent, specific, non-competitive and reversible inhibitor of acetylcholinesterase (AChE) used for the treatment of mild to moderate dementia of the Alzheimer's type.",379.49,"120014-06-4",{"v":75,"d":"75.00"},197.63,"N/A","N/A","http://selleckchem.com/products/donepezil.html","C24H29NO3","free base","Aricept, Donepezilo","COC1=CC2=C(C=C1OC)C(=O)C(CC3CCN(CC3)CC4=CC=CC=C4)C2",4.569,3,0,6]
["S5075","Acotiamide","b3","L4000-11","in 10mM DMSO","AChR","Neuronal Signaling","Acotiamide (Acofide, Z388) is a novel acetylcholinesterase inhibitor with fundus-relaxing and gastroprokinetic properties.",450.55,"185106-16-5",{"v":90,"d":"90.00"},199.76,"<1","N/A","http://selleckchem.com/products/acotiamide.html","C21H30N4O5S","free base","Acofide, Z388","COC1=C(OC)C=C(C(=O)NC2=NC(=CS2)C(=O)NCCN(C(C)C)C(C)C)C(=C1)O",2.565,5,3,10]
["S5085","Azamethiphos","c3","L4000-11","in 10mM DMSO","Others","Others","Azamethiphos is an organophosphate (OP) pesticide used to combat sea lice infestations in farmed salmonids.",324.68,"35575-96-3",{"v":64,"d":"64.00"},197.12,"N/A","N/A","http://selleckchem.com/products/azamethiphos.html","C9H10ClN2O5PS","free base","N/A","CO[P](=O)(OC)SCN1C(=O)OC2=C1N=CC(=C2)Cl",1.793,5,0,5]
["S5088","Labetalone hydrochloride","d3","L4000-11","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Labetalone hydrochloride (Benzoic amide) is hydrochloride form of labetalone, a blocker of both alpha- and beta-adrenergic receptors that is used as an antihypertensive.",362.85,"96441-14-4",{"v":72,"d":"72.00"},198.43,"N/A","N/A","http://selleckchem.com/products/labetalone-hydrochloride.html","C19H22N2O3.HCl","hydrochloride","Benzoic amide","Cl.CC(CCC1=CC=CC=C1)NCC(=O)C2=CC(=C(O)C=C2)C(N)=O",{"v":2.92,"d":"2.920"},2,3,8]
["S5100","Pralidoxime Iodide","e3","L4000-11","in 10mM DMSO","AChR","Neuronal Signaling","Pralidoxime Iodide (2-PAM) is an antidote approved for reactivation of inhibited acetylcholinesterase (AChE) in organophosphate poisoning.",264.06,"94-63-3",{"v":52,"d":"52.00"},196.92,"N/A","N/A","http://selleckchem.com/products/pralidoxime-lodide.html","C7H9N2O.I","iodide salt","2-PAM","[I-].C[N+]1=C(C=CC=C1)\\C=N\\O",{"v":-1.56,"d":"-1.560"},1,0,1]
["S5101","Tabersonine hydrochloride","f3","L4000-11","in 10mM DMSO","Beta Amyloid","Neuronal Signaling","Tabersonine, an ingredient extracted from the bean of Voacanga africana, is a potent inhibitor against Aβ(1−42) aggregation and toxicity.",372.89,"29479-00-3",{"v":40,"d":"40.00"},107.27,"N/A","N/A","http://selleckchem.com/products/tabersonine-hydrochloride.html","C21H24N2O2.HCl","hydrochloride","N/A","Cl.CCC12CC(=C3NC4=C(C=CC=C4)C35CCN(CC=C1)C25)C(=O)OC",{"v":0,"d":"0.000"},0,0,0]
["S5110","Safflower Yellow","g3","L4000-11","in 10mM DMSO","Dyes","Others","Safflower Yellow (Safflor Yellow, SY), the main active constituent of the traditional Chinese medicine Safflower, is known as a neuroprotective agent that indirectly attenuates neuroinflammation.",910.78,"36338-96-2",{"v":100,"d":"100.00"},{"v":109.8,"d":"109.80"},"N/A","N/A","http://selleckchem.com/products/safflower-yellow.html","C43H42O22","free base","Safflor Yellow","OCC1OC(C(O)C(O)C1O)C2(O)C(=C(\\C=C/3C(=O)C(=C(O)C(O)(C4OC(CO)C(O)C(O)C4O)C3=O)C(=O)\\C=C\\C5=CC=C(O)C=C5)C(=O)C(=C2O)C(=O)\\C=C\\C6=CC=C(O)C=C6)O",{"v":0,"d":"0.000"},0,0,0]
["S5141","Pyrithioxin","h3","L4000-11","in 10mM DMSO","Others","Others","Pyrithioxin (Bonifen, Encefabol, Pyritinol, Vitamin B6 disulfide) is a neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity.",368.47,"1098-97-1",{"v":60,"d":"60.00"},162.84,"N/A","N/A","http://selleckchem.com/products/pyrithioxin.html","C16H20N2O4S2","free base","Bonifen, Encefabol, Pyritinol, Vitamin B6 disulfide","CC1=NC=C(CSSCC2=CN=C(C)C(=C2CO)O)C(=C1O)CO",{"v":0,"d":"0.000"},0,0,0]
["S5153","Tetrahydroberberine","a4","L4000-11","in 10mM DMSO","5-HT Receptor,ADC Cytotoxin,Dopamine Receptor","Neuronal Signaling","Tetrahydroberberine (Canadine) is an isoquinoline alkaloid with micromolar affinity for dopamine D2 (antagonist, pKi = 6.08) and 5-HT1A (agonist, pKi = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors.",339.39,"522-97-4",{"v":6,"d":"6.00"},17.68,"N/A","N/A","http://selleckchem.com/products/tetrahydroberberine.html","C20H21NO4","free base","Canadine","COC1=CC=C2CC3N(CCC4=CC5=C(OCO5)C=C34)CC2=C1OC",{"v":3.4,"d":"3.400"},4,0,2]
["S5154","Tetrahydropiperine","b4","L4000-11","in 10mM DMSO","Others","Others","Tetrahydropiperine (Cosmoperine), derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.",289.37,"23434-88-0",{"v":57,"d":"57.00"},196.98,"N/A","N/A","http://selleckchem.com/products/tetrahydropiperine.html","C17H23NO3","free base","Cosmoperine","O=C(CCCCC1=CC2=C(OCO2)C=C1)N3CCCCC3",3.332,3,0,5]
["S5177","Naproxen","c4","L4000-11","in 10mM DMSO","COX","Immunology & Inflammation","Naproxen is an anti-inflammatory agent with analgesic and antipyretic properties. It is a nonselective inhibitor of COX-1 and COX-2.",230.26,"22204-53-1",{"v":46,"d":"46.00"},199.77,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/naproxen.html","C14H14O3","Free Base","N/A","COC1=CC2=CC=C(C=C2C=C1)C(C)C(O)=O",2.849,2,0,3]
["S5179","Ropivacaine Mesilate","d4","L4000-11","in 10mM DMSO","Others","Others","Ropivacaine Mesilate is the mesylate form of ropivacaine, which is a member of the amino amide class of local anesthetics.",370.51,"854056-07-8",{"v":74,"d":"74.00"},199.72,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/ropivacaine-mesilate.html","C18H30N2O4S","Mesilate","Ropivacaine Mesylate","CCCN1CCCCC1C(=O)NC2=C(C)C=CC=C2C.C[S](O)(=O)=O",{"v":3.44,"d":"3.440"},1,1,4]
["S5203","Sulbutiamine","e4","L4000-11","in 10mM DMSO","Vitamin","Metabolism","Sulbutiamine is a synthetic derivative of thiamine (vitamin B1), belonging to a class of supplements shown to help improve memory, learning capacity, decision-making, concentration, and focus.",702.89,"3286-46-2",{"v":100,"d":"100.00"},142.27,{"v":-1,"d":"-1.00"},-1.42,"https://www.selleckchem.com/products/sulbutiamine.html","C32H46N8O6S2","free base","Bisibutiamine, Vitaberin, Youvitan","CC(C)C(=O)OCCC(/SS\\C(CCOC(=O)C(C)C)=C(C)/N(CC1=C(N)N=C(C)N=C1)C=O)=C(C)/N(CC2=CN=C(C)N=C2N)C=O",1.356,10,2,19]
["S5217","Arformoterol Tartrate","f4","L4000-11","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Arformoterol Tartrate is the tartrate salt of arformoterol, a long-acting beta-2 adrenergic agonist with bronchodilator activity.",494.49,"200815-49-2",{"v":99,"d":"99.00"},200.21,{"v":-1,"d":"-1.00"},-2.02,"https://www.selleckchem.com/products/arformoterol-tartrate.html","C23H30N2O10","Tartrate","(R, R)-Formoterol","COC1=CC=C(CC(C)NCC(O)C2=CC(=C(O)C=C2)NC=O)C=C1.OC(C(O)C(O)=O)C(O)=O",-2.446,4,6,11]
["S5222","Coluracetam","g4","L4000-11","in 10mM DMSO","GluR","Neuronal Signaling","Coluracetam (BCI-540, MKC-231) is a nootropic belonging to the racetam family of drugs with cognitive enhancing and neuroprotective effects.",{"v":341.4,"d":"341.40"},"135463-81-9",{"v":68,"d":"68.00"},199.18,"<1","N/A","http://selleckchem.com/products/coluracetam.html","C19H23N3O3","free base","MKC-231, BCI-540","CC1=C(C)C2=C(O1)N=C3CCCCC3=C2NC(=O)CN4CCCC4=O",1.975,4,1,3]
["S5224","Adrafinil","h4","L4000-11","in 10mM DMSO","Others","Others","Adrafinil (benzhydrylsulfinylacetohydroxamic acid, adrafinyl, CRL-40028) is a mild central nervous system stimulant drug directly affecting CNS function. It is used to relieve excessive sleepiness and inattention in elderly patients.",289.35,"63547-13-7",{"v":57,"d":"57.00"},196.99,"N/A","N/A","http://selleckchem.com/products/adrafinil.html","C15H15NO3S","free base","benzhydrylsulfinylacetohydroxamic acid, adrafinyl, CRL-40028","ONC(=O)C[S](=O)C(C1=CC=CC=C1)C2=CC=CC=C2",1.745,2,1,5]
["S5238","Solifenacin (YM905)","a5","L4000-11","in 10mM DMSO","AChR","Neuronal Signaling","Solifenacin (YM905) is a competitive muscarinic receptor antagonist. The binding of acetylcholine to these receptors, particularly the M3 receptor subtype, plays a critical role in the contraction of smooth muscle.",362.46,"242478-37-1",{"v":72,"d":"72.00"},198.64,{"v":-1,"d":"-1.00"},-2.76,"https://www.selleckchem.com/products/solifenacin.html","C23H26N2O2","free base","N/A","O=C(OC1CN2CCC1CC2)N3CCC4=C(C=CC=C4)C3C5=CC=CC=C5",4.029,2,0,3]
["S5239","Paroxetine mesylate","b5","L4000-11","in 10mM DMSO","Serotonin Transporter","Neuronal Signaling","Paroxetine Mesylate(BRL-29060A mesylate,FG-7051 mesylate) is the mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties.",425.47,"217797-14-3",{"v":85,"d":"85.00"},199.78,{"v":-1,"d":"-1.00"},-2.35,"http://selleckchem.com/products/paroxetine-mesylate.html","C19H20FNO3.CH4O3S","Mesylate","BRL-29060A mesylate,FG-7051 mesylate","C[S](O)(=O)=O.FC1=CC=C(C=C1)C2CCNCC2COC3=CC=C4OCOC4=C3",2.815,3,1,4]
["S5247","Selamectin","c5","L4000-11","in 10mM DMSO","Parasite","Microbiology","Selamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a  wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas.",769.96,"220119-17-5",{"v":100,"d":"100.00"},129.88,"N/A","N/A","https://www.selleckchem.com/products/selamectin.html","C43H63NO11","free base","UK-124114","COC1CC(OC(C)C1O)OC/2C(C)\\C=C\\C=C\\3COC4/C(=N/O)C(=CC(C(=O)OC5CC(C\\C=C2C)OC6(CCC(C)C(O6)C7CCCCC7)C5)C34O)C",5.315,9,1,4]
["S5253","Cisapride (R 51619)","d5","L4000-11","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Cisapride (R 51619, Kaudalit, Kinestase, Prepulsid, Presid, Pridesia, Propulsid) is a nonselective 5-HT4 receptor agonist with gastroprokinetic effects.",465.95,"81098-60-4",{"v":93,"d":"93.00"},199.59,"<1","N/A","http://selleckchem.com/products/cisapride.html","C23H29ClFN3O4","Benzamide","Kaudalit, Kinestase, Prepulsid, Presid, Pridesia, Propulsid","COC1CN(CCCOC2=CC=C(F)C=C2)CCC1NC(=O)C3=C(OC)C=C(N)C(=C3)Cl",2.785,4,2,9]
["S5255","Nicardipine","e5","L4000-11","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Nicardipine is a potent calcium channel blockader with marked vasodilator action.",479.52,"55985-32-5",{"v":95,"d":"95.00"},198.11,{"v":30,"d":"30.00"},62.56,"https://www.selleckchem.com/products/nicardipine.html","C26H29N3O6","Dihydropyridine calcium channel blocker","YC-93","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OCCN(C)CC3=CC=CC=C3)C",3.488,4,1,11]
["S5257","Doxapram","f5","L4000-11","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Doxapram is a central respiratory stimulant with a brief duration of action. Doxapram is a selective TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel inhibitor with EC50 of 410 nM, 37 μM, 9 μM, respectively.",378.51,"309-29-5",{"v":75,"d":"75.00"},198.15,"<1","N/A","http://selleckchem.com/products/doxapram.html","C24H30N2O2","free base","N/A","CCN1CC(CCN2CCOCC2)C(C1=O)(C3=CC=CC=C3)C4=CC=CC=C4",3.043,2,0,6]
["S5258","Revefenacin","g5","L4000-11","in 10mM DMSO","AChR","Neuronal Signaling","Revefenacin (TD-4208, GSK-1160724) is a potent, lung-selective, long-acting muscarinic antagonist that may be for the treatment of respiratory disease.",597.75,"864750-70-9",{"v":100,"d":"100.00"},167.29,"<1","N/A","http://selleckchem.com/products/revefenacin.html","C35H43N5O4","Quinuclidinyl","TD-4208, GSK-1160724","CN(CCN1CCC(CC1)OC(=O)NC2=CC=CC=C2C3=CC=CC=C3)C(=O)C4=CC=C(CN5CCC(CC5)C(N)=O)C=C4",3.833,4,2,11]
["S5266","Stiripentol","h5","L4000-11","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Stiripentol (BCX2600) is a third-generation anti-epileptic drug that enhances GABAergic neurotransmission. It is an inhibitor of cytochrome P450.",234.29,"49763-96-4",{"v":46,"d":"46.00"},196.34,{"v":13,"d":"13.00"},55.49,"http://selleckchem.com/products/stiripentol.html","C14H18O3","Dioxolane","BCX2600","CC(C)(C)C(O)/C=C/C1=CC=C2OCOC2=C1",2.955,2,1,3]
["S5269","J147","a6","L4000-11","in 10mM DMSO","MAO","Neuronal Signaling","J147, a curcumin derivative, is a potent neurogenic and neuroprotective compound developed for the treatment of neurodegenerative conditions associated with aging.",350.33,"1146963-51-0",{"v":70,"d":"70.00"},199.81,"N/A","N/A","http://selleckchem.com/products/j147.html","C18H17F3N2O2","free base","N/A","COC1=CC(=CC=C1)/C=N/N(C(=O)C(F)(F)F)C2=CC=C(C)C=C2C",4.845,3,0,5]
["S5274","GS967","b6","L4000-11","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","GS967 (GS458967) is a potent and selective inhibitor of late INa with anti-arrhythmic actions.",347.22,"1262618-39-2",{"v":45,"d":"45.00"},{"v":129.6,"d":"129.60"},"<1","N/A","http://selleckchem.com/products/gs967.html","C14H7F6N3O","free base","GS458967","FC(F)(F)OC1=CC=C(C=C1)C2=C[N]3C(=NN=C3C(F)(F)F)C=C2",5.307,3,0,4]
["S5279","Fendiline hydrochloride","c6","L4000-11","in 10mM DMSO","Calcium Channel,Ras","Transmembrane Transporters","Fendiline hydrochloride is the hydrochloride salt form of Fendiline, which is an L-type calcium channel blocker and also a specific inhibitor of K-Ras plasma membrane targeting with no detectable effect on the localization of H- and N-Ras.",351.91,"13636-18-5",{"v":70,"d":"70.00"},198.91,"N/A","N/A","http://selleckchem.com/products/fendiline-hydrochloride.html","C23H25N.HCl","hydrochloride","N/A","Cl.CC(NCCC(C1=CC=CC=C1)C2=CC=CC=C2)C3=CC=CC=C3",5.772,0,1,7]
["S5281","Dapiprazole Hydrochloride","d6","L4000-11","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Dapiprazole Hydrochloride (Glamidolo Hydrochloride, Reversil Hydrochloride) is the hydrochloride salt form of dapiprazole, an alpha-adrenergic blocker used to reverse mydriasis after eye examination.",361.91,"72822-13-0",{"v":21,"d":"21.00"},58.03,{"v":72,"d":"72.00"},198.94,"http://selleckchem.com/products/dapiprazole-hydrochloride.html","C19H27N5.HCl","hydrochloride","Glamidolo Hydrochloride, Reversil Hydrochloride","Cl.CC1=C(C=CC=C1)N2CCN(CC2)CCC3=NN=C4CCCC[N]34",3.384,2,0,4]
["S5286","Ramatroban","e6","L4000-11","in 10mM DMSO","Prostaglandin Receptor","Metabolism","Ramatroban (BAY u 3405) is a thromboxane A2(TxA2) receptor antagonist with Ki value of 10 to 13 nM. It also antagonizes a newly identified PGD2 receptor, CRTh2 expressed on the inflammatory cells.",416.47,"116649-85-5",{"v":83,"d":"83.00"},199.29,"<1","N/A","http://selleckchem.com/products/ramatroban.html","C21H21FN2O4S","free base","BAY u 3405","OC(=O)CC[N]1C2=C(CC(CC2)N[S](=O)(=O)C3=CC=C(F)C=C3)C4=CC=CC=C14",{"v":3.51,"d":"3.510"},3,1,6]
["S5302","6-Methoxy-2-naphthoic acid","f6","L4000-11","in 10mM DMSO","NMDAR","Neuronal Signaling","6-Methoxy-2-naphthoic acid (6-Methoxy-2-naphthalenecarboxylic acid) is an modulator of NMDAR.",202.21,"2471-70-7",{"v":40,"d":"40.00"},197.81,"<1","N/A","http://selleckchem.com/products/6-methoxy-2-naphthoic-acid.html","C12H10O3","free base","6-Methoxy-2-naphthalenecarboxylic acid","COC1=CC2=CC=C(C=C2C=C1)C(O)=O",2.351,2,0,2]
["S5303","Afalanine (N-Acetyl-DL-phenylalanine)","g6","L4000-11","in 10mM DMSO","Others","Others","Afalanine (N-Acetyl-DL-phenylalanine, Afalanine) acts as an antidepressant and a metabolite.",207.23,"2901-75-9",{"v":41,"d":"41.00"},197.85,{"v":-1,"d":"-1.00"},-4.83,"https://www.selleckchem.com/products/n-acetyl-dl-phenylalanine.html","C11H13NO3","Amino acid","Afalanine","CC(=O)NC(CC1=CC=CC=C1)C(O)=O",0.895,2,1,4]
["S5305","Bromisoval","h6","L4000-11","in 10mM DMSO","Others","Others","Bromisoval (Bromovalerylurea, Isobromyl, Bromaral, BRN 1773255) is a hypnotic and sedative of the bromoureide group with anti-inflammatory effects.",223.07,"496-67-3",{"v":44,"d":"44.00"},197.25,"N/A","N/A","http://selleckchem.com/products/bromisoval.html","C6H11BrN2O2","free base","Bromovalerylurea, Isobromyl, Bromaral, BRN 1773255, 2-Bromo-N-carbamoyl-3-methylbutanamide","CC(C)C(Br)C(=O)NC(N)=O",0.952,2,2,2]
["S5309","Propyphenazone (4-Isopropylantipyrine)","a7","L4000-11","in 10mM DMSO","COX","Immunology & Inflammation","Propyphenazone(4-Isopropylantipyrine, Isopropyrine), an analgesic and antipyretic agent, is a selective cyclooxygenase-2 inhibitor with anti-inflammatory activity.",230.31,"479-92-5",{"v":46,"d":"46.00"},199.73,"N/A","N/A","http://selleckchem.com/products/propyphenazone.html","C14H18N2O","free base","Isopropylantipyrine, Isopropyrine","CC(C)C1=C(C)N(C)N(C2=CC=CC=C2)C1=O",2.373,1,0,2]
["S5319","Imepitoin","b7","L4000-11","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Imepitoin(ELB-138,AWD 131-138) is a centrally acting anti-epileptic which crosses the blood brain barrier and is used for the treatment of canine idiopathic epilepsy.  AWD 131-138 (Imepitoin) is an antiepileptic and antianxietic drug, AWD 131-138 can stimulate different recombinant isoforms of the rat GABA(A) receptor through the benzodiazepine binding site.",279.72,"188116-07-6",{"v":30,"d":"30.00"},107.25,"<1","N/A","http://selleckchem.com/products/awd-131-138.html","C13H14ClN3O2","free base","ELB-138,AWD 131-138","ClC1=CC=C(C=C1)N2CC(=NC2=O)N3CCOCC3",{"v":1.44,"d":"1.440"},3,0,2]
["S5326","Dolasetron","c7","L4000-11","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Dolasetron(MDL-73147EF) is a highly specific and selective serotonin 5-HT3 receptor antagonist. It has minimal activity at other known serotonin receptors, and has low affinity for dopamine receptors.",324.37,"115956-12-2",{"v":64,"d":"64.00"},197.31,"<1","N/A","https://www.selleckchem.com/products/dolasetron.html","C19H20N2O3","free base","MDL-73147EF","O=C1CN2C3CC(CC2CC1C3)OC(=O)C4=C[NH]C5=C4C=CC=C5",2.035,3,1,3]
["S5329","FAAH-IN-2","d7","L4000-11","in 10mM DMSO","FAAH","Metabolism","FAAH-IN-2 is an inhibitor of fatty acid amide hydrolase (FAAH).",319.72,"184475-71-6",{"v":40,"d":"40.00"},125.11,"<1","N/A","http://selleckchem.com/products/faah-in-2.html","C15H11ClFN3O2","free base","N/A","COC1=C(O)C=C2C(=NC=NC2=C1)NC3=CC=C(F)C(=C3)Cl",4.088,3,2,3]
["S5337","Rauwolscine hydrochloride","e7","L4000-11","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Rauwolscine hydrochloride (Isoyohimbine, α-Yohimbine, corynanthidine) is the hydrochloride salt form of Rauwolscine, a specific and potent α2 antagonist with Ki of 12 nM.",{"v":390.9,"d":"390.90"},"6211-32-1",{"v":7,"d":"7.00"},17.91,"N/A","N/A","http://selleckchem.com/products/rauwolscine-hydrochloride.html","C21H26N2O3.HCl","hydrochloride","Isoyohimbine hydrochloride, α-Yohimbine hydrochloride, corynanthidine hydrochloride","Cl.COC(=O)C1C(O)CCC2CN3CCC4=C([NH]C5=C4C=CC=C5)C3CC12",3.204,2,2,2]
["S5341","Metroprolol succinate","f7","L4000-11","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Metroprolol Succinate (Metoprolol succinate) is the succinate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity.",652.82,"98418-47-4",{"v":100,"d":"100.00"},153.18,{"v":100,"d":"100.00"},153.18,"http://selleckchem.com/products/metroprolol-succinate.html","C34H56N2O10","succinate","Metoprolol succinate","COCCC1=CC=C(OCC(O)CNC(C)C)C=C1.COCCC2=CC=C(OCC(O)CNC(C)C)C=C2.OC(=O)CCC(O)=O",-2.255,6,4,21]
["S5346","2-Phenylethylamine hydrochloride","g7","L4000-11","in 10mM DMSO","Others","Others","2-Phenylethylamine hydrochloride (β-Phenylethylamine, benzeneethanamine, β-aminoethylbenzene) is the hydrochloride salt form of 2-Phenylethylamine, which is an aromatic amine acting as a monoaminergic neuromodulator or a neurotransmitter in the human central nervous system.",157.64,"156-28-5",{"v":31,"d":"31.00"},196.65,"N/A","N/A","http://selleckchem.com/products/2-phenylethylamine-hydrochloride.html","C8H11N.HCl","hydrochloride","β-Phenylethylamine hydrochloride, benzeneethanamine hydrochloride, β-aminoethylbenzene hydrochloride","Cl.NCCC1=CC=CC=C1",1.639,0,1,2]
["S5347","2-Phenylethylamine","h7","L4000-11","in 10mM DMSO","Others","Others","2-Phenylethylamine (β-Phenylethylamine, benzeneethanamine, β-aminoethylbenzene) is a natural monoamine alkaloid that functions as a monoaminergic neuromodulator or a neurotransmitter in the human central nervous system.,",121.18,"64-04-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/2-phenylethylamine.html","C8H11N","free base","β-Phenylethylamine, benzeneethanamine, β-aminoethylbenzene","NCCC1=CC=CC=C1",1.257,0,1,2]
["S5357","Safinamide","a8","L4000-11","in 10mM DMSO","MAO","Metabolism","Safinamide (EMD-1195686, PNU-15774E) is an orally active, selective, reversible <v>monoamine oxidase-B inhibitor with both dopaminergic and non-dopaminergic (glutamatergic) properties. The IC50 value of safinamide for MAO-B is 98 nM.",302.34,"133865-89-1",{"v":60,"d":"60.00"},198.45,{"v":-1,"d":"-1.00"},-3.31,"http://selleckchem.com/products/safinamide.html","C17H19FN2O2","free base","EMD-1195686, PNU-15774E","CC(NCC1=CC=C(OCC2=CC=CC(=C2)F)C=C1)C(N)=O",2.478,2,2,7]
["S5358","Regadenoson","b8","L4000-11","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","Regadenoson (CVT-3146, Lexiscan) is a selective A2A adenosine receptor agonist with coronary vasodilating activity.",390.35,"313348-27-5",{"v":56,"d":"56.00"},143.46,"<1","N/A","http://selleckchem.com/products/regadenoson.html","C15H18N8O5","free base","CVT-3146, Lexiscan","CNC(=O)C1=C[N](N=C1)C2=NC3=C(N=C[N]3C4OC(CO)C(O)C4O)C(=N2)N",-1.925,6,5,4]
["S5360","Diflorasone","c8","L4000-11","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Diflorasone acts as a corticosteroid hormone receptor agonist with anti-inflammatory and immunosuppressive properties.",410.45,"2557-49-5",{"v":82,"d":"82.00"},199.78,"<1","N/A","https://www.selleckchem.com/products/diflorasone.html","C22H28F2O5","free base","N/A","CC1CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO",1.546,2,2,2]
["S5363","Pikamilone","d8","L4000-11","in 10mM DMSO","Others","Others","Pikamilone is a drug having a central (vegetotropic and vascular) and peripheral (vasodilating) mechanisms of action.",208.21,"34562-97-5",{"v":33,"d":"33.00"},158.49,"N/A","N/A","http://selleckchem.com/products/pikamilone.html","C10H12N2O3","free base","N/A","OC(=O)CCCNC(=O)C1=CN=CC=C1",-0.062,3,1,5]
["S5366","Fipronil","e8","L4000-11","in 10mM DMSO","Anti-infection","Microbiology","Fipronil (Fluocyanobenpyrazole, Termidor) is a recalcitrant phenylpyrazole-based pesticide used for flea/tick treatment and termite control that is distributed in urban aquatic environments via stormwater and contributes to stream toxicity.",437.15,"120068-37-3",{"v":87,"d":"87.00"},199.02,"N/A","N/A","http://selleckchem.com/products/fipronil.html","C12H4Cl2F6N4OS","free base","Fluocyanobenpyrazole, Termidor","NC1=C(C(=N[N]1C2=C(Cl)C=C(C=C2Cl)C(F)(F)F)C#N)[S](=O)C(F)(F)F",5.579,2,1,4]
["S5371","Ajmaline","f8","L4000-11","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Ajmaline (Cardiorythmine, Tachmalin), found in the root of Rauwolfia serpentina, is a class Ia antiarrhythmic agent.",326.43,"4360-12-7",{"v":65,"d":"65.00"},199.12,{"v":-1,"d":"-1.00"},-3.06,"https://www.selleckchem.com/products/ajmaline.html","C20H26N2O2","free base","Cardiorythmine, Tachmalin","CCC1C(O)N2C3CC1C4C(O)C5(CC24)C3N(C)C6=CC=CC=C56",1.932,0,2,1]
["S5385","Imidafenacin","g8","L4000-11","in 10mM DMSO","AChR","GPCR & G Protein","Imidafenacin (KRP-197, ONO-8025) is a urinary antispasmodic of the anticholinergic class. It is a novel antimuscarinic agent with safety and efficacy, has been clinically used for the treatment of overactive bladder. Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM; less potent for M2 receptors(IC50=4.13 nM). IC50 value: 0.3 nM(M3).",{"v":319.4,"d":"319.40"},"170105-16-5",{"v":63,"d":"63.00"},197.24,{"v":-1,"d":"-1.00"},-3.13,"https://www.selleckchem.com/products/imidafenacin.html","C20H21N3O","free base","KRP-197, ONO-8025","CC1=NC=C[N]1CCC(C(N)=O)(C2=CC=CC=C2)C3=CC=CC=C3",{"v":2.55,"d":"2.550"},2,1,6]
["S5392","Mepivacaine","h8","L4000-11","in 10mM DMSO","Others","Others","Mepivacaine (Carbocaine) is a local anesthetic indicated for infiltration, nerve block, and epidural anesthesia.",246.35,"96-88-8",{"v":49,"d":"49.00"},198.91,{"v":-1,"d":"-1.00"},-4.06,"https://www.selleckchem.com/products/mepivacaine.html","C15H22N2O","free base","Carbocaine","CN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",2.981,1,1,2]
["S5398","Nefazodone hydrochloride","a9","L4000-11","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Nefazodone hydrochloride (BMY-13754-1) is the hydrochloride salt form of nefazodone, which is an atypical antidepressant showing antagonistic activity on serotonin reuptake.",506.47,"82752-99-6",{"v":22,"d":"22.00"},43.44,{"v":-1,"d":"-1.00"},-1.97,"https://www.selleckchem.com/products/nefazodone-hydrochloride.html","C25H33Cl2N5O2","free base","BMY-13754-1","Cl.CCC1=NN(CCCN2CCN(CC2)C3=CC(=CC=C3)Cl)C(=O)N1CCOC4=CC=CC=C4",4.797,3,0,10]
["S5399","Chlorprothixene hydrochloride","b9","L4000-11","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Chlorprothixene HCl (Minithixen hydrochloride, Truxal hydrochloride, NSC 169899, NSC 56379, NSC 78193) is the  hydrochloride salt form of chlorprothixene, a typical antipsychotic drug of the thioxanthene (tricyclic) class. It exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors.",352.32,"6469-93-8",{"v":70,"d":"70.00"},198.68,{"v":-1,"d":"-1.00"},-2.84,"https://www.selleckchem.com/products/chlorprothixene-hydrochloride.html","C18H19Cl2NS","free base","Minithixen hydrochloride, Truxal hydrochloride, NSC 169899, NSC 56379, NSC 78193","Cl.CN(C)CC\\C=C/1C2=C(SC3=C1C=C(Cl)C=C3)C=CC=C2",5.505,0,0,3]
["S5401","Tegaserod Maleate","c9","L4000-11","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Tegaserod Maleate(HTF-919) is a hydrogen maleate salt form of tegaserod, which is a 5-HT4 receptor partial agonist and binds with high affinity to 5-HT4 receptors. It has limited affinity for 5-HT1 receptors and no appreciable affinity for other 5-HT receptors, muscarinic, adrenergic, dopaminergic or opiate receptors.",417.46,"189188-57-6",{"v":83,"d":"83.00"},198.82,"<1","N/A","http://selleckchem.com/products/tegaserod-maleate.html","C16H23N5O.C4H4O4","maleate","HTF-919","CCCCCNC(=N)N/N=C/C1=C[NH]C2=C1C=C(OC)C=C2.OC(=O)\\C=C/C(O)=O",{"v":3.17,"d":"3.170"},4,3,11]
["S5418","Parecoxib Sodium","d9","L4000-11","in 10mM DMSO","COX","Immunology & Inflammation","Parecoxib Sodium (SC-69124) is a water-soluble, injectable sodium salt form of parecoxib, which is a potent and selective inhibitor of cyclo-oxygenase-2 (COX2).",{"v":392.4,"d":"392.40"},"198470-85-8",{"v":78,"d":"78.00"},198.77,{"v":-1,"d":"-1.00"},-2.55,"https://www.selleckchem.com/products/parecoxib-sodium.html","C19H17N2NaO4S","free base","SC-69124 Sodium","CCC(=O)N([Na])[S](=O)(=O)C1=CC=C(C=C1)C2=C(C)ON=C2C3=CC=CC=C3",{"v":3.36,"d":"3.360"},5,0,5]
["S5419","1,4-Cineole","e9","L4000-11","in 10mM DMSO","TRP Channel","Transmembrane Transporters","1,4-Cineole (Isocineole) is a widely distributed, natural, oxygenated monoterpene. 1,4-Cineole, present in eucalyptus oil, activates both human TRPM8 and human TRPA1.",154.25,"470-67-7",{"v":30,"d":"30.00"},194.49,"N/A","N/A","http://selleckchem.com/products/1-4-cineole.html","C10H18O","free base","Isocineole","CC(C)C12CCC(C)(CC1)O2",2.282,1,0,1]
["S5424","Carbaryl","f9","L4000-11","in 10mM DMSO","AChR","Neuronal Signaling","Carbaryl (1-naphthyl methylcarbamate) is a carbamate insecticide and parasiticide and also a potent anticholinesterase agent belonging to the carbamate group of reversible cholinesterase inhibitors.",201.22,"63-25-2",{"v":40,"d":"40.00"},198.79,"N/A","N/A","http://selleckchem.com/products/carbaryl.html","C12H11NO2","free base","1-naphthyl methylcarbamate","CNC(=O)OC1=C2C=CC=CC2=CC=C1",2.502,2,1,2]
["S5428","Promazine hydrochloride","g9","L4000-11","in 10mM DMSO","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Promazine (Romtiazin, Sinophenin) is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine H1-receptors with antipsychotic effects.",320.88,"53-60-1",{"v":64,"d":"64.00"},199.45,"N/A","N/A","http://selleckchem.com/products/promazine-hydrochloride.html","C17H20N2S.HCl","hydrochloride","Romtiazin hydrochloride, Sinophenin hydrochloride","Cl.CN(C)CCCN1C2=CC=CC=C2SC3=C1C=CC=C3",4.457,0,0,4]
["S5430","Metoprolol","h9","L4000-11","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Metoprolol is a cardioselective β1-adrenergic blocking agent with log Kd values of −7.26±0.07, −6.89±0.09, −5.16±0.12 for β1, β2, and β3 adrenoceptors, respectively. It is used for acute myocardial infarction, heart failure, angina pectoris and mild to moderate hypertension.",267.36,"51384-51-1",{"v":53,"d":"53.00"},198.23,"N/A","N/A","http://selleckchem.com/products/metoprolol.html","C15H25NO3","free base","N/A","COCCC1=CC=C(OCC(O)CNC(C)C)C=C1",1.757,2,2,9]
["S5432","Dibenamine Hydrochloride","a10","L4000-11","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Dibenamine (N-(2-Chloroethyl)dibenzylamine, Sympatholytin, Dibenzylchlorethamine) is an irreversible blocker of α1 adrenoceptors.",296.23,"55-43-6",{"v":59,"d":"59.00"},199.17,"N/A","N/A","http://selleckchem.com/products/dibenamine-hydrochloride.html","C16H18ClN.HCl","hydrochloride","N-(2-Chloroethyl)dibenzylamine Hydrochloride, Sympatholytin Hydrochloride, Dibenzyl chlorethylamine, Dibenzylchlorethamine","Cl.ClCCN(CC1=CC=CC=C1)CC2=CC=CC=C2",4.534,0,0,6]
["S5444","4-Bromo-3-hydroxybenzoic acid","b10","L4000-11","in 10mM DMSO","Decarboxylase","Metabolism","4-bromo-3-hydroxybenzoic acid is a potent inhibitor of the enzyme histidine decarboxylase with resultant inhibition of histamine formation in mammals.",217.02,"14348-38-0",{"v":43,"d":"43.00"},198.14,"N/A","N/A","http://selleckchem.com/products/4-bromo-3-hydroxybenzoic-acid.html","C7H5BrO3","free base","N/A","OC(=O)C1=CC(=C(Br)C=C1)O",1.966,1,1,1]
["S5447","Triprolidine Hydrochloride","c10","L4000-11","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Triprolidine Hydrochloride is the hydrochloride salt form of Triprolidine, which is the first generation histamine H1 antagonist used in allergic rhinitis.",332.87,"6138-79-0",{"v":62,"d":"62.00"},186.26,"N/A","N/A","http://selleckchem.com/products/triprolidine-hydrochloride.html","C19H22N2.HCl.H2O","hydrochloride, hydrate","N/A","O.Cl.CC1=CC=C(C=C1)\\C(=C/CN2CCCC2)C3=NC=CC=C3",4.249,1,0,4]
["S5457","Curculigoside","d10","L4000-11","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Curculigoside (Curculigoside A), a diterpenoid triepoxide, is one of the main bioactive phenolic compounds isolated from the rhizome of Curculigo orchioides Gaertn. and has potent antioxidant, anti-osteoporotic, immunomodulatory, and neuroprotective effects.",466.44,"85643-19-2",{"v":93,"d":"93.00"},199.38,{"v":15,"d":"15.00"},32.16,"http://selleckchem.com/products/curculigoside.html","C22H26O11","free base","Curculigoside A","COC1=C(C(=O)OCC2=CC(=CC=C2OC3OC(CO)C(O)C(O)C3O)O)C(=CC=C1)OC",0.822,6,5,9]
["S5464","Psoralidin","e10","L4000-11","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Psoralidin, a naturally occurring coumestan isolated from the fractions of organic solvents such as ethylacetate, hexane, or n-butanol of the seed extract of Psoralea corylifolia L., has a variety of biological activities such as anticancer, antioxidant, antibacterial, antidepressant, anti-inflammatory activities, and regulation of insulin signaling. It is an agonist for both estrogen receptor (ER)α and ERβ with binding affinities (IC50s) of 1.03 and 24.6 μM, respectively.",336.34,"18642-23-4",{"v":67,"d":"67.00"},{"v":199.2,"d":"199.20"},"<1","N/A","http://selleckchem.com/products/psoralidin.html","C20H16O5","free base","N/A","CC(C)=CCC1=CC2=C(OC(=O)C3=C2OC4=C3C=CC(=C4)O)C=C1O",4.917,3,2,2]
["S5466","Saikosaponin A","f10","L4000-11","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Saikosaponin A is a triterpene saponin derived from the medicinal plant, Bupleurum chinensis DC. (Umbelliferae). It has a variety of pharmacological benefits, including anti-inﬂammatory, immunomodulatory, and anti-bacterial activities.",780.98,"20736-09-8",{"v":100,"d":"100.00"},128.04,"<1","N/A","https://www.selleckchem.com/products/saikosaponin-a.html","C42H68O13","free base","N/A","CC1OC(OC2CCC3(C)C(CCC4(C)C3C=CC56OCC7(CCC(C)(C)CC57)C(O)CC46C)C2(C)CO)C(O)C(OC8OC(CO)C(O)C(O)C8O)C1O",1.107,5,8,6]
["S5472","Nafronyl oxalate salt","g10","L4000-11","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Nafronyl oxalate salt is the oxalate salt form of nafronyl, which is a selective antagonist of 5-HT2 receptors and a vasodilator used in the management of peripheral and cerebral vascular disorders.",473.56,"3200-06-4",{"v":94,"d":"94.00"},{"v":198.5,"d":"198.50"},{"v":94,"d":"94.00"},{"v":198.5,"d":"198.50"},"http://selleckchem.com/products/nafronyl-oxalate-salt.html","C24H33NO3.C2H2O4","oxalate","N/A","CCN(CC)CCOC(=O)C(CC1CCCO1)CC2=C3C=CC=CC3=CC=C2.OC(=O)C(O)=O",1.048,5,0,12]
["S5476","Rolapitant","h10","L4000-11","in 10mM DMSO","Neurokinin Receptor","Neuronal Signaling","Rolapitant (SCH-619734) is a selective and competitive antagonist of human substance P/NK1 receptors with antiemetic activity. It has a high affinity for the human NK1 receptor of 0.66 nM and high selectivity over the human NK2 and NK3 subtypes of >1000-fold, as well as preferential affinity for human, guinea pig, gerbil and monkey NK1 receptors over rat, mouse and rabbit.",500.48,"552292-08-7",{"v":100,"d":"100.00"},199.81,"N/A","N/A","https://www.selleckchem.com/products/rolapitant.html","C25H26F6N2O2","NK1 receptor antagonists","SCH-619734","CC(OCC1(CCC2(CCC(=O)N2)CN1)C3=CC=CC=C3)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F",4.761,2,2,7]
["S5478","Dantrolene sodium","a11","L4000-11","in 10mM DMSO","ADC Cytotoxin,Calcium Channel","Transmembrane Transporters","Dantrolene sodium(F 440) acts as a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.",336.23,"14663-23-1",{"v":67,"d":"67.00"},199.27,{"v":-1,"d":"-1.00"},-2.97,"https://www.selleckchem.com/products/s5478-dantrolene-sodium.html","C14H9N4NaO5","free base","F 440","[Na+].[O-]C1=NC(=O)CN1/N=C/C2=CC=C(O2)C3=CC=C(C=C3)[N+]([O-])=O",1.769,4,0,4]
["S5479","Cloperastine hydrochloride","b11","L4000-11","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Cloperastine (HT-11) is a drug with a central antitussive effect, and is also endowed with an antihistaminic activity.",366.32,"14984-68-0",{"v":73,"d":"73.00"},199.28,"N/A","N/A","http://selleckchem.com/products/cloperastine-hydrochloride.html","C20H24ClNO.HCl","hydrochloride","HT-11 hydrochloride","Cl.ClC1=CC=C(C=C1)C(OCCN2CCCCC2)C3=CC=CC=C3",5.348,1,0,6]
["S5480","Clidinium Bromide","c11","L4000-11","in 10mM DMSO","AChR","Neuronal Signaling","Clidinium Bromide(Ro 2-3773) is an anticholinergic drug.",432.35,"3485-62-9",{"v":86,"d":"86.00"},198.91,"N/A","N/A","http://selleckchem.com/products/clidinium-bromide.html","C22H26NO3.Br","bromide","Ro 2-3773","[Br-].C[N+]12CCC(CC1)C(C2)OC(=O)C(O)(C3=CC=CC=C3)C4=CC=CC=C4",-0.622,2,0,5]
["S5481","Molindone hydrochloride","d11","L4000-11","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Molindone hydrochloride is the hydrochloride salt form of molindone, a conventional antipsychotic used in the therapy of schizophrenia. It is a dopamine D2/D5 receptor antagonist.",312.83,"15622-65-8",{"v":9,"d":"9.00"},28.77,"N/A","N/A","http://selleckchem.com/products/molindone-hydrochloride.html","C16H24N2O2.HCl","hydrochloride","N/A","Cl.CCC1=C(C)[NH]C2=C1C(=O)C(CC2)CN3CCOCC3",2.522,2,1,3]
["S5482","Prilocaine hydrochloride","e11","L4000-11","in 10mM DMSO","Others","Others","Prilocaine hydrochloride is the hydrochloride salt form of prilocaine, which is a local anesthetic.",256.77,"1786-81-8",{"v":51,"d":"51.00"},198.62,"N/A","N/A","https://www.selleckchem.com/products/prilocaine-hydrochloride.html","C13H20N2O.HCl","hydrochloride","N/A","Cl.CCCNC(C)C(=O)NC1=CC=CC=C1C",2.645,1,2,5]
["S5483","Tribenzagan Hydrochloride","f11","L4000-11","in 10mM DMSO","Others","Others","Tribenzagan Hydrochloride (Trimethobenzamide) is an orally available, antiemetic agent used in the therapy of nausea and vomiting associated with medications and gastrointestinal, viral and other illnesses.",424.92,"554-92-7",{"v":84,"d":"84.00"},197.68,"N/A","N/A","http://selleckchem.com/products/trimethobenzamide-hydrochloride.html","C21H28N2O5.HCl","hydrochloride","Trimethobenzamide Hydrochloride","Cl.COC1=C(OC)C(=CC(=C1)C(=O)NCC2=CC=C(OCCN(C)C)C=C2)OC",3.076,5,1,10]
["S5485","Desipramine Hydrochloride","g11","L4000-11","in 10mM DMSO","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Desipramine hydrochloride (Desmethylimipramine, Norimipramine, EX-4355, G-35020, JB-8181, NSC-114901) is a dibenzazepine-derivative tricyclic antidepressant that acts as a selective norepinephrine reuptake inhibitor. It also shows weak serotonin reuptake inhibitory, α1-blocking, antihistamine, and anticholinergic effects.",302.84,"58-28-6",{"v":60,"d":"60.00"},198.12,"N/A","N/A","http://selleckchem.com/products/desipramine-hydrochloride.html","C18H22N2.HCl","hydrochloride","Desmethylimipramine, Norimipramine, EX-4355, G-35020, JB-8181, NSC-114901","Cl.CNCCCN1C2=C(CCC3=C1C=CC=C3)C=CC=C2",4.234,0,1,4]
["S5486","Fluorometholone","h11","L4000-11","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Fluorometholone (Oxylone) is a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. It is usually used as eye drops in the treatment of allergic and inflammatory conditions of the eye.",376.46,"426-13-1",{"v":75,"d":"75.00"},199.22,"<1","N/A","http://selleckchem.com/products/fluorometholone.html","C22H29FO4","free base","Oxylone","CC1CC2C3CCC(O)(C(C)=O)C3(C)CC(O)C2(F)C4(C)C=CC(=O)C=C14",2.312,2,1,1]
["S5490","Disopyramide","a2","L4000-12","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Disopyramide is a class IA antiarrhythmic drug which acts via blockade of sodium channels depressing phase 0 of the action potential. Disopyramide possesses significant negative inotropic, anticholinergic effects and enhances AV nodal conduction.",339.47,"3737-09-5",{"v":67,"d":"67.00"},197.37,"N/A","N/A","http://selleckchem.com/products/disopyramide.html","C21H29N3O","Antiarrhythmic agent","N/A","CC(C)N(CCC(C(N)=O)(C1=CC=CC=C1)C2=NC=CC=C2)C(C)C",3.417,2,1,8]
["S5493","Atropine sulfate","b2","L4000-12","in 10mM DMSO","AChR","Neuronal Signaling","Atropine Sulfate (Sulfatropinol, Atropette, Tropintran) is the sulfate salt of atropine, which is a natural alkaloid anticholinergic agent and has potent antimuscarinic effects.",676.82,"55-48-1",{"v":18,"d":"18.00"},26.59,"N/A","N/A","https://www.selleckchem.com/products/atropine-sulfate.html","C34H46N2O6.H2SO4","sulfate","Sulfatropinol, Atropette, Tropintran","CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN4C5CCC4CC(C5)OC(=O)C(CO)C6=CC=CC=C6.O[S](O)(=O)=O",2.835,4,2,10]
["S5494","Salbutamol","c2","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Salbutamol (Albuterol) is a short-acting, selective beta2-adrenergic receptor agonist used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases.",239.31,"18559-94-9",{"v":47,"d":"47.00"},{"v":196.4,"d":"196.40"},"N/A","N/A","https://www.selleckchem.com/products/salbutamol.html","C13H21NO3","free base","Albuterol","CC(C)(C)NCC(O)C1=CC=C(O)C(=C1)CO",0.941,0,4,5]
["S5498","Betahistine mesylate","d2","L4000-12","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Betahistine mesylate is the mesylate salt form of Betahistine, a histamine analog and H3 receptor agonist that serves as a vasodilator.",328.41,"54856-23-4",{"v":65,"d":"65.00"},197.92,"N/A","N/A","http://selleckchem.com/products/betahistine-mesylate.html","C8H12N2.2CH4O3S","dimethanesulfonate","N/A","CNCCC1=CC=CC=N1.C[S](O)(=O)=O.C[S](O)(=O)=O",-0.148,1,1,3]
["S5501","Hydrocortisone acetate","e2","L4000-12","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Hydrocortisone Acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties.",{"v":404.5,"d":"404.50"},"50-03-3",{"v":80,"d":"80.00"},197.78,"N/A","N/A","https://www.selleckchem.com/products/hydrocortisone-acetate.html","C23H32O6","free base","Cortisol 21-acetate","CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3C(O)CC12C",1.662,4,1,4]
["S5504","Ropivacaine","f2","L4000-12","in 10mM DMSO","Others","Others","Ropivacaine is a member of the amino amide class of local anesthetics.",{"v":274.4,"d":"274.40"},"84057-95-4",{"v":23,"d":"23.00"},83.82,"<1","N/A","https://www.selleckchem.com/products/ropivacaine.html","C17H26N2O","Amide local anesthetics","N/A","CCCN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",3.853,1,1,4]
["S5507","Trimebutine maleate","g2","L4000-12","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","Trimebutine maleate is the maleate salt form of trimebutine, which is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects.",503.54,"34140-59-5",{"v":100,"d":"100.00"},198.59,{"v":-1,"d":"-1.00"},-1.99,"https://www.selleckchem.com/products/trimebutine-maleate.html","C26H33NO9","Maleate salt","3, 4, 5-Trimethoxybenzoic Acid 2-(Dimethylamino)-2-phenylbutyl Ester Maleate Salt;","CCC(COC(=O)C1=CC(=C(OC)C(=C1)OC)OC)(N(C)C)C2=CC=CC=C2.OC(=O)\\C=C/C(O)=O",{"v":1.12,"d":"1.120"},7,0,12]
["S5511","Ethyl (triphenylphosphoranylidene) acetate","h2","L4000-12","in 10mM DMSO","AChR,BChE","Neuronal Signaling","Ethyl (triphenylphosphoranylidene) acetate (Triphenylcarbethoxymethylenephosphorane, (Carbethoxymethylene)triphenylphosphorane) may act as an inhibitor of cholinesterase that inhibits AChE and BChE.",348.37,"1099-45-2",{"v":69,"d":"69.00"},198.07,"N/A","N/A","http://selleckchem.com/products/ethyl-triphenylphosphoranylidene-acetate.html","C22H21O2P","free base","(Carbethoxymethylene)triphenylphosphorane, Triphenylcarbethoxymethylenephosphorane, Ethyl 2-(triphenylphosphoranylidene)acetate","CCOC(=O)C=[P](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3",5.227,2,0,6]
["S5514","Lanthanum(III) chloride heptahydrate","a3","L4000-12","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Lanthanum(III) chloride is the inorganic compound used in biochemical research to block the activity of divalent cation channels, mainly calcium channels.",371.37,"10025-84-0",{"v":50,"d":"50.00"},134.64,"N/A","N/A","http://selleckchem.com/products/lanthanum-iii-chloride-heptahydrate.html","Cl3La.7H2O","salt","N/A","O.O.O.O.O.O.O.Cl[La](Cl)Cl",0.006,0,0,0]
["S5520","Phenidone","b3","L4000-12","in 10mM DMSO","COX,Lipoxygenase","Immunology & Inflammation","Phenidone (1-phenyl-3-pyrazolidinone), a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), is an organic compound that is primarily used as a photographic developer.",162.19,"92-43-3",{"v":32,"d":"32.00"},{"v":197.3,"d":"197.30"},"N/A","N/A","http://selleckchem.com/products/phenidone.html","C9H10N2O","free base","1-phenyl-3-pyrazolidinone","O=C1CCN(N1)C2=CC=CC=C2",1.112,1,1,1]
["S5527","Salmeterol","c3","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Salmeterol (Astmerole, GR-33343X, SN408D) is a long-acting beta2-adrenergic receptor agonist with Ki value of 1.5 nM for WT β2AR and shows very high selectivity for the WT β2AR(β1Ki/β2Ki ratio of approximately 1500).",415.57,"89365-50-4",{"v":83,"d":"83.00"},199.73,"<1","N/A","http://selleckchem.com/products/salmeterol.html","C25H37NO4","free base","Astmerole, GR-33343X, SN408D","OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC2=CC=CC=C2",4.251,1,4,16]
["S5537","Tizanidine","d3","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Tizanidine is an imidazoline derivative and a centrally acting α2 adrenergic agonist used as a muscle relaxant for therapy of acute muscle spasms and chronic spasticity.",253.71,"51322-75-9",{"v":50,"d":"50.00"},197.07,{"v":15,"d":"15.00"},59.12,"http://selleckchem.com/products/tizanidine.html","C9H8ClN5S","α2-adrenergic agonists","N/A","ClC1=C(NC2=NCCN2)C3=NSN=C3C=C1",1.817,3,2,2]
["S5538","Tropisetron","e3","L4000-12","in 10mM DMSO","5-HT Receptor,AChR","Neuronal Signaling","Tropisetron (ICS 205-930) is a 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.",284.35,"89565-68-4",{"v":10,"d":"10.00"},35.17,{"v":56,"d":"56.00"},196.94,"http://selleckchem.com/products/tropisetron.html","C17H20N2O2","free base","ICS 205-930","CN1C2CCC1CC(C2)OC(=O)C3=C[NH]C4=C3C=CC=C4",2.608,2,1,3]
["S5540","Landiolol hydrochloride","f3","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Landiolol hydrochloride (ONO-1101) is the hydrochloride salt form of Landiolol, which is an ultra-short-acting β1 selective adrenoceptor antagonist.",546.05,"144481-98-1",{"v":100,"d":"100.00"},183.13,{"v":100,"d":"100.00"},183.13,"https://www.selleckchem.com/products/landiolol-hydrochloride.html","C25H39N3O8.HCl","hydrochloride","ONO-1101 hydrochloride","Cl.CC1(C)OCC(COC(=O)CCC2=CC=C(OCC(O)CNCCNC(=O)N3CCOCC3)C=C2)O1",{"v":0.4,"d":"0.400"},7,3,14]
["S5542","7-Nitroindazole","g3","L4000-12","in 10mM DMSO","NOS","Immunology & Inflammation","7-Nitroindazole, a heterocyclic compound, acts as a selective inhibitor for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.",163.13,"2942-42-9",{"v":32,"d":"32.00"},196.16,"N/A","N/A","https://www.selleckchem.com/products/7-nitroindazole.html","C7H5N3O2","free base","N/A","[O-][N+](=O)C1=CC=CC2=C1[NH]N=C2",1.368,1,1,1]
["S5547","Hydroxylammonium chloride","h3","L4000-12","in 10mM DMSO","Others","Others","Hydroxylammonium chloride (Hydroxylamine hydrochloride) is the hydrochloric acid salt of hydroxylamine, which is a biological intermediate in the nitrification and in the anammox.",69.46,"5470-11-1","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/hydroxylammonium-chloride.html","HCl.H3NO","chloride","Hydroxylamine hydrochloride","Cl.NO",-0.305,0,1,0]
["S5551","6-Paradol","a4","L4000-12","in 10mM DMSO","COX","Immunology & Inflammation","6-Paradol is a minor constituent of ginger, mainly formed from 6-gingerol via 6-shogaol, and exhibits a variety of biological activities including anti-cancer, anti-inflammatory, and anti-oxidative activities. Paradol is an inhibitor of cyclooxygenase (COX)-2.",278.39,"27113-22-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/6-paradol.html","C17H26O3","free base","N/A","CCCCCCCC(=O)CCC1=CC=C(O)C(=C1)OC",{"v":4.74,"d":"4.740"},2,1,10]
["S5556","(-)-Sparteine Sulfate","b4","L4000-12","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Sparteine Sulfate, a quinolizidine alkaloid, is the sulfate form of sparteini, which is a sodium channel blocker used as an oxytocic and an anti-arrhythmia agent.",422.54,"6160-12-9","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/sparteini-sulfas.html","C15H26N2.H2SO4.5H2O","sulfate pentahydrate","N/A","O.O.O.O.O.O[S](O)(=O)=O.C1CCN2CC3CC(CN4CCCCC34)C2C1",{"v":0.72,"d":"0.720"},0,0,0]
["S5559","(+/-)-tetrahydropalmatine","c4","L4000-12","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","(+/-)-tetrahydropalmatine, a plant alkaloid used as an ingredient in dietary supplement products, is a potent and selective D1 receptor antagonist.",355.43,"2934-97-6",{"v":16,"d":"16.00"},45.02,"<1","N/A","http://selleckchem.com/products/tetrahydropalmatine.html","C21H25NO4","free base","Rotundine","COC1=C(OC)C=C2C3CC4=CC=C(OC)C(=C4CN3CCC2=C1)OC",3.599,4,0,4]
["S5561","Ethacrynic Acid","d4","L4000-12","in 10mM DMSO","Others","NF-κB","Ethacrynic Acid is a loop or high ceiling diuretic used for the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.",303.14,"58-54-8",{"v":61,"d":"61.00"},201.23,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/ethacrynic-acid.html","C13H12Cl2O4","Free Base","N/A","CCC(=C)C(=O)C1=C(Cl)C(=C(OCC(O)=O)C=C1)Cl",3.963,3,0,6]
["S5563","Thioridazine hydrochloride","e4","L4000-12","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Thioridazine (Aldazine, Mellaril) is a potent antianxiety and antipsychotic agent.",407.04,"130-61-0",{"v":81,"d":"81.00"},{"v":199,"d":"199.00"},"N/A","N/A","http://selleckchem.com/products/thioridazine-hydrochloride.html","C21H26N2S2.HCl","hydrochloride","Aldazine, Mellaril","Cl.CSC1=CC2=C(SC3=CC=CC=C3N2CCC4CCCCN4C)C=C1",5.945,0,0,4]
["S5564","Xylazine","f4","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Xylazine is a partial alpha-2 adrenergic agonist that is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals.",220.33,"7361-61-7",{"v":44,"d":"44.00"},{"v":199.7,"d":"199.70"},{"v":-1,"d":"-1.00"},-4.54,"https://www.selleckchem.com/products/xylazine.html","C12H16N2S","free base","N/A","CC1=C(NC2=NCCCS2)C(=CC=C1)C",3.265,1,1,2]
["S5565","Triflupromazine hydrochloride","g4","L4000-12","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Triflupromazine hydrochloride (Fluopromazine) is an antipsychotic medication of the phenothiazine class.",388.88,"1098-60-8",{"v":78,"d":"78.00"},200.58,"N/A","N/A","https://www.selleckchem.com/products/triflupromazine-hydrochloride.html","C18H20ClF3N2S","salt","Fluopromazine hydrochloride","Cl.CN(C)CCCN1C2=C(SC3=CC=C(C=C13)C(F)(F)F)C=CC=C2",5.399,0,0,5]
["S5567","Trimethadione","h4","L4000-12","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Trimethadione is an oxazolidinedione anticonvulsant and often used to treat epileptic conditions that are resistant to other treatments.",143.14,"127-48-0",{"v":28,"d":"28.00"},195.61,"N/A","N/A","http://selleckchem.com/products/trimethadione.html","C6H9NO3","oxazolidinedione","N/A","CN1C(=O)OC(C)(C)C1=O",0.488,3,0,0]
["S5579","Chelidonic acid","a5","L4000-12","in 10mM DMSO","Caspase,Decarboxylase,Immunology & Inflammation related,Interleukins,NF-κB","Immunology & Inflammation","Chelidonic acid (Jerva acid, Jervaic acid, γ-Pyrone-2,6-dicarboxylic acid) is a secondary metabolite found in several plants with therapeutic potential in allergic disorders in experimental animals. Chelidonic acid inhibits IL-6 production by blocking NF-κB and caspase-1 in HMC-1 cells. Chelidonic acid is also an inhibitor of glutamate decarboxylase with Ki of 1.2 μM.",{"v":184.1,"d":"184.10"},"99-32-1",{"v":4,"d":"4.00"},21.73,"N/A","N/A","http://selleckchem.com/products/chelidonic-acid.html","C7H4O6","free base","Jerva acid, Jervaic acid, γ-Pyrone-2,6-dicarboxylic acid","OC(=O)C1=CC(=O)C=C(O1)C(O)=O",-0.479,4,0,2]
["S5595","3-Carene","b5","L4000-12","in 10mM DMSO","COX,phosphatase","Immunology & Inflammation","3-Carene (Carene, Delta-3-Carene) is a bicyclic monoterpene in essential oils extracted from pine trees. 3-Carene have potent pharmacological effects on COX-2 overexpression and LPS-induced migration of Raw264.7 macrophages. 3‐carene is shown to significantly stimulate the activity and expression of alkaline phosphatase, an early phase marker of osteoblastic differentiation.",136.23,"13466-78-9","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/3-carene.html","C10H16","free base","Carene, Delta-3-Carene","CC1=CCC2C(C1)C2(C)C",2.872,0,0,0]
["S5596","(1S)-(-)-α-Pinene","c5","L4000-12","in 10mM DMSO","GABA Receptor","Neuronal Signaling","α-Pinene is found in the oils of many species of many coniferous trees, notably the pine and has insecticidal activity.  (1S)-(-)-α-Pinene is a monoterpene and shows sleep enhancing property through a direct binding to GABAA-benzodiazepine (BZD) receptors by acting as a partial modulator at the BZD binding site.",136.23,"7785-26-4","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/1s-alpha-pinene.html","C10H16","free base","N/A","CC1=CCC2CC1C2(C)C",2.872,0,0,0]
["S5616","4-Methylcatechol","d5","L4000-12","in 10mM DMSO","Others","Others","4-Methylcatechol (P-Methylcatechol, 3,4-Dihydroxytoluene, Homocatechol) is an inducer of nerve growth factor. It is used to synthesize antimicrobial and antioxidant.",124.14,"452-86-8",{"v":24,"d":"24.00"},193.33,{"v":-1,"d":"-1.00"},-8.06,"https://www.selleckchem.com/products/4-methylcatechol.html","C7H8O2","free base","P-Methylcatechol, 3,4-Dihydroxytoluene, Homocatechol","CC1=CC(=C(O)C=C1)O",1.832,0,2,0]
["S5619","Betahistine","e5","L4000-12","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Betahistine is an antivertigo drug that primarily acts as a histamine H1 agonist.",136.19,"5638-76-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",{"v":10,"d":"10.00"},"N/A",{"v":0,"d":"0.00"},"https://www.selleckchem.com/products/betahistine.html","C8H12N2","free base","N/A","CNCCC1=NC=CC=C1",{"v":0.68,"d":"0.680"},1,1,3]
["S5620","NSI-189","f5","L4000-12","in 10mM DMSO","Others","Neuronal Signaling","NSI-189, a small molecule with enhanced neurogenic activity, is a potential antidepressant for the treatment of major depressive disorder (MDD), cognitive impairment and neurodegeneration.",{"v":366.5,"d":"366.50"},"1270138-40-3",{"v":73,"d":"73.00"},199.18,"<1","N/A","http://selleckchem.com/products/nsi-189.html","C22H30N4O","free base","N/A","CC(C)CCNC1=NC=CC=C1C(=O)N2CCN(CC2)CC3=CC=CC=C3",3.562,2,1,7]
["S5640","Ethyl caffeate","g5","L4000-12","in 10mM DMSO","COX,NF-κB,NOS,PGES","NF-κB","Ethyl caffeate, a naturally occurring compound found in Bidens pilosa, suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro.",208.21,"102-37-4",{"v":41,"d":"41.00"},196.92,{"v":-1,"d":"-1.00"},{"v":-4.8,"d":"-4.80"},"https://www.selleckchem.com/products/ethyl-caffeate.html","C11H12O4","Ester","ETHYL 3, 4-DIHYDROXYCINNAMATE","CCOC(=O)/C=C/C1=CC(=C(O)C=C1)O",2.018,2,2,4]
["S5642","Homovanillic acid","h5","L4000-12","in 10mM DMSO","Others","Others","Homovanillic acid (Vanillacetic acid) is a major catecholamine metabolite that is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain.",182.17,"306-08-1",{"v":36,"d":"36.00"},197.62,"N/A","N/A","https://www.selleckchem.com/products/homovanillic-acid.html","C9H10O4","Dopamine","Vanillacetic acid","COC1=C(O)C=CC(=C1)CC(O)=O",1.236,2,1,3]
["S5647","Emedastine Difumarate","a6","L4000-12","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Emedastine Difumarate (Rapimine, Emedastine fumarate) is the difumarate salt form of emedastine, a second generation, selective histamine H1 receptor antagonist with anti-allergic activity.",534.56,"87233-62-3",{"v":100,"d":"100.00"},187.07,{"v":100,"d":"100.00"},187.07,"http://selleckchem.com/products/emedastine-difumarate.html","C17H26N4O.2C4H4O4","Difumarate","Rapimine, Emedastine fumarate","CCOCC[N]1C2=C(C=CC=C2)N=C1N3CCCN(C)CC3.OC(=O)\\C=C\\C(O)=O.OC(=O)\\C=C\\C(O)=O",-0.464,6,0,9]
["S5649","Hydroxyzine pamoate","b6","L4000-12","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Hydroxyzine Pamoate is the pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties.",763.27,"10246-75-0",{"v":100,"d":"100.00"},131.01,{"v":-1,"d":"-1.00"},-1.31,"https://www.selleckchem.com/products/hydroxyzine-pamoate.html","C44H43ClN2O8","free base","N/A","OCCOCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3.OC(=O)C4=C(O)C(=C5C=CC=CC5=C4)CC6=C7C=CC=CC7=CC(=C6O)C(O)=O",1.794,3,3,12]
["S5654","Indacaterol","c6","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor.",392.49,"312753-06-3",{"v":52,"d":"52.00"},132.49,"<1","N/A","http://selleckchem.com/products/indacaterol.html","C24H28N2O3","free base","N/A","CCC1=CC2=C(CC(C2)NCC(O)C3=CC=C(O)C4=C3C=CC(=O)N4)C=C1CC",{"v":3.93,"d":"3.930"},1,4,6]
["S5655","Venlafaxine","d6","L4000-12","in 10mM DMSO","Serotonin Transporter","Neuronal Signaling","Venlafaxine (Wy 45030) is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.",{"v":277.4,"d":"277.40"},"93413-69-5",{"v":55,"d":"55.00"},198.27,"<1","N/A","http://selleckchem.com/products/venlafaxine.html","C17H27NO2","Phenethylamine","Wy 45030","COC1=CC=C(C=C1)C(CN(C)C)C2(O)CCCCC2",3.022,1,0,5]
["S5656","Diphenylpyraline hydrochloride","e6","L4000-12","in 10mM DMSO","Dyes,Histamine Receptor","Neuronal Signaling","Diphenylpyraline hydrochloride is the hydrochloride salt form of diphenylpyraline, which is an antihistamine used in the treatment of allergic rhinitis, hay fever, and allergic skin disorders.",317.85,"132-18-3",{"v":63,"d":"63.00"},198.21,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/diphenylpyraline-hydrochloride.html","C19H24ClNO","hydrochloride","N/A","Cl.CN1CCC(CC1)OC(C2=CC=CC=C2)C3=CC=CC=C3",3.738,1,0,4]
["S5659","Emedastine","f6","L4000-12","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Emedastine is a potent, high affinity histamine H1-receptor-selective antagonist with Ki of 1.3 ±0.1 nM for H1-receptors while considerably weaker at H2- (K1 = 49,067 ± 11,113 nM) and H3-receptors (Ki = 12,430 ± 1,282 nM).",302.41,"87233-61-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",{"v":10,"d":"10.00"},"N/A","N/A","http://selleckchem.com/products/emedastine.html","C17H26N4O","free base","N/A","CCOCC[N]1C2=C(C=CC=C2)N=C1N3CCCN(C)CC3",2.492,2,0,5]
["S5662","Ranitidine","g6","L4000-12","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Ranitidine(AH-19065) is an H2 histamine receptor antagonist that works by blocking histamine and thus decreasing the amount of acid released by cells of the stomach.",{"v":314.4,"d":"314.40"},"66357-35-5",{"v":63,"d":"63.00"},200.38,{"v":-1,"d":"-1.00"},-3.18,"https://www.selleckchem.com/products/ranitidine.html","C13H22N4O3S","free base","AH-19065","CNC(/NCCSCC1=CC=C(CN(C)C)O1)=C\\[N+]([O-])=O",1.039,1,2,10]
["S5663","Minaprine dihydrochloride","h6","L4000-12","in 10mM DMSO","MAO","Metabolism","Minaprine dihydrochloride is hydrochloride salt form of Minaprine, which acts as a reversible inhibitor of MAO-A in rats and weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.",{"v":371.3,"d":"371.30"},"25905-77-5",{"v":74,"d":"74.00"},{"v":199.3,"d":"199.30"},{"v":74,"d":"74.00"},{"v":199.3,"d":"199.30"},"https://www.selleckchem.com/products/minaprine-dihydrochloride.html","C17H24Cl2N4O","free base","N/A","Cl.Cl.CC1=CC(=NN=C1NCCN2CCOCC2)C3=CC=CC=C3",3.583,3,1,5]
["S5664","Orphenadrine Hydrochloride","a7","L4000-12","in 10mM DMSO","NMDAR","Neuronal Signaling","Orphenadrine Hydrochloride is an uncompetitive NMDAR antagonist, H1 receptor antagonist and nonselective mAChR antagonist with muscle relaxant activity.",305.84,"341-69-5",{"v":61,"d":"61.00"},199.45,{"v":-1,"d":"-1.00"},-3.27,"https://www.selleckchem.com/products/orphenadrine-hydrochloride.html","C18H24ClNO","free base","N/A","Cl.CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2C",4.253,1,0,6]
["S5665","Drofenine Hydrochloride","b7","L4000-12","in 10mM DMSO","BChE","Neuronal Signaling","Drofenine hydrochloride is a potent competitive inhibitor of BChE. It is an anticholinergic that acts both at the level of the nerves and the muscle fibers.",353.93,"548-66-3",{"v":71,"d":"71.00"},{"v":200.6,"d":"200.60"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/drofenine-hydrochloride.html","C20H32ClNO2","hydrochloride","N/A","Cl.CCN(CC)CCOC(=O)C(C1CCCCC1)C2=CC=CC=C2",5.106,2,0,9]
["S5666","Moxisylyte hydrochloride","c7","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Moxisylyte hydrochloride (thymoxamine) is an alpha-adrenergic blocking agent used for the treatment of Raynaud's disease.",315.84,"964-52-3",{"v":63,"d":"63.00"},199.47,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/moxisylyte-hydrochloride.html","C16H26ClNO3","hydrochloride","thymoxamine hydrochloride","Cl.CC(C)C1=C(OCCN(C)C)C=C(C)C(=C1)OC(C)=O",3.782,3,0,7]
["S5669","Isoxsuprine hydrochloride","d7","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Isoxsuprine hydrochloride is a beta-adrenergic agonist with vasodilator activity.",337.84,"579-56-6",{"v":68,"d":"68.00"},201.28,{"v":4,"d":"4.00"},11.84,"http://www.selleckchem.com/products/isoxsuprine-hydrochloride.html","C18H24ClNO3","hydrochloride","N/A","Cl.CC(COC1=CC=CC=C1)NC(C)C(O)C2=CC=C(O)C=C2",3.384,1,3,7]
["S5670","Chloropyramine hydrochloride","e7","L4000-12","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Chloropyramine hydrochloride (Halopyramine) is a histamine receptor H1 antagonist and has anti-cholinergic, antispasmodic, and antiallergic effects.",326.26,"6170-42-9",{"v":65,"d":"65.00"},199.23,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/chloropyramine-hydrochloride.html","C16H21Cl2N3","hydrochloride","Halopyramine hydrochloride","Cl.CN(C)CCN(CC1=CC=C(Cl)C=C1)C2=CC=CC=N2",4.149,1,0,6]
["S5673","Mivacurium chloride","f7","L4000-12","in 10mM DMSO","Others","Others","Mivacurium chloride is a rapid, non-depolarising, neuromuscular blocking agent of short duration, used therefore as anesthetic, to provide skeletal muscle relaxation in minor surgical operations, in emergency surgical procedures of short to intermediate duration and during intubation of the trachea.",1100.17,"106861-44-3",{"v":100,"d":"100.00"},{"v":90.9,"d":"90.90"},{"v":100,"d":"100.00"},{"v":90.9,"d":"90.90"},"http://www.selleckchem.com/products/mivacurium-chloride.html","C58H80Cl2N2O14","chloride","N/A","[Cl-].[Cl-].COC1=CC2=C(C=C1OC)C(CC3=CC(=C(OC)C(=C3)OC)OC)[N+](C)(CCCOC(=O)CC\\C=C\\CCC(=O)OCCC[N+]4(C)CCC5=C(C=C(OC)C(=C5)OC)C4CC6=CC(=C(OC)C(=C6)OC)OC)CC2",0.836,14,0,30]
["S5679","Dolasetron Mesylate","g7","L4000-12","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Dolasetron Mesylate (Anzemet hydrate,MDL-73147EF) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.",420.48,"115956-13-3",{"v":84,"d":"84.00"},199.77,{"v":28,"d":"28.00"},66.59,"http://www.selleckchem.com/products/dolasetron-mesylate.html","C20H24N2O6S","Mesylate","Anzemet hydrate,MDL-73147EF","C[S](O)(=O)=O.O=C1CN2C3CC(CC2CC1C3)OC(=O)C4=C[NH]C5=C4C=CC=C5",1.621,3,1,3]
["S5683","Isoproterenol sulfate dihydrate","h7","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Isoproterenol Sulfate is the sulfate salt form of isoproterenol, a beta-adrenergic receptor agonist with bronchodilator activity.",556.62,"299-95-6",{"v":100,"d":"100.00"},179.66,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/isoproterenol-sulfate-dihydrate.html","C22H40N2O12S","dihydrate","N/A","O.O.CC(C)NCC(O)C1=CC=C(O)C(=C1)O.CC(C)NCC(O)C2=CC=C(O)C(=C2)O.O[S](O)(=O)=O",1.177,0,8,8]
["S5690","Triacanthine","a8","L4000-12","in 10mM DMSO","Others","Others","Triacanthine, which could be isolated from the leaves of G. triacanthos, shows hypertensive activity, also cardiotonic, antispasmodic and a respiratory analeptic.",203.24,"2365-40-4",{"v":41,"d":"41.00"},201.73,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/triacanthine.html","C10H13N5","Free Base","N/A","CC(C)=CCNC1=NC=NC2=C1N=C[NH]2",1.579,3,2,3]
["S5693","Levomilnacipran Hydrochloride","b8","L4000-12","in 10mM DMSO","Serotonin Transporter","Neuronal Signaling","Levomilnacipran Hydrochloride is a selective serotonin and norepinephrine reuptake inhibitor with antidepressant activity.",282.81,"175131-60-9",{"v":57,"d":"57.00"},201.55,{"v":57,"d":"57.00"},201.55,"http://www.selleckchem.com/products/levomilnacipran-hydrochloride.html","C15H23ClN2O","Hydrochloride","N/A","Cl.CCN(CC)C(=O)C1(CC1CN)C2=CC=CC=C2",{"v":1.67,"d":"1.670"},1,1,5]
["S5698","Ketorolac tromethamine salt","c8","L4000-12","in 10mM DMSO","COX","Immunology & Inflammation","Ketorolac tromethamine is a synthetic pyrrolizine carboxylic acid derivative with anti-inflammatory, analgesic and antipyretic properties. It is a non-selective COX inhibitor with IC50s of 20 nM for both COX-1 and COX-2.",{"v":376.4,"d":"376.40"},"74103-07-4",{"v":75,"d":"75.00"},199.26,{"v":75,"d":"75.00"},199.26,"http://www.selleckchem.com/products/ketorolac-tromethamine-salt.html","C19H24N2O6","tromethamine salt","N/A","NC(CO)(CO)CO.OC(=O)C1CC[N]2C1=CC=C2C(=O)C3=CC=CC=C3",-2.028,2,4,6]
["S5701","Alvimopan dihydrate (LY246736 dihydrate)","d8","L4000-12","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","Alvimopan (LY-246736) is a potent, relatively nonselective opioid antagonist with Ki values of 0.77, 4.4, and 40 nM for the μ, δ, and κ opioid receptors, respectively, displaying >100-fold selectivity over other aminergic G-protein-coupled receptors.",460.56,"170098-38-1",{"v":92,"d":"92.00"},199.76,{"v":-1,"d":"-1.00"},-2.17,"https://www.selleckchem.com/products/alvimopan-dihydrate.html","C25H36N2O6","free base","N/A","O.O.CC1CN(CCC1(C)C2=CC=CC(=C2)O)CC(CC3=CC=CC=C3)C(=O)NCC(O)=O",0.096,2,2,8]
["S5703","Carvedilol Phosphate","e8","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity.",513.48,"610309-89-2",{"v":100,"d":"100.00"},198.23,{"v":-1,"d":"-1.00"},-1.98,"https://www.selleckchem.com/products/carvedilol-phosphate.html","C24H29N2O8P.1/2H2O","Phosphate","N/A","COC1=C(OCCNCC(O)COC2=CC=CC3=C2C4=C([NH]3)C=CC=C4)C=CC=C1.O[P](O)(O)=O",{"v":4.28,"d":"4.280"},3,3,10]
["S5705","Raceanisodamine","f8","L4000-12","in 10mM DMSO","Others","Others","Raceanisodamine (7β-Hydroxyhyoscyamine) is the active ingredient of Chinese herbal extracts that has vasoactive activity used to treat acute disseminated intravascular coagulation in patients in bacteremic shock.",305.37,"17659-49-3",{"v":61,"d":"61.00"},199.76,{"v":30,"d":"30.00"},98.24,"http://selleckchem.com/products/raceanisodamine.html","C17H23NO4","free base","7β-Hydroxyhyoscyamine","CN1C2CC(O)C1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",{"v":0.63,"d":"0.630"},2,2,5]
["S5709","Norgestrel","g8","L4000-12","in 10mM DMSO","ROS","Immunology & Inflammation","Norgestrel (WY-3707, SH-70850, SH-850, FH 122-A) is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception. It also has strong neuroprotective activity.",312.45,"6533-00-2",{"v":62,"d":"62.00"},198.43,"<1","N/A","http://selleckchem.com/products/norgestrel.html","C21H28O2","free base","WY-3707, SH-70850, SH-850, FH 122-A","CCC12CCC3C(CCC4=CC(=O)CCC34)C1CCC2(O)C#C",4.771,1,0,1]
["S5710","Ambroxol","h8","L4000-12","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Ambroxol, a substituted benzylamine, is an active metabolite of bromhexine. It is a potent inhibitor of the neuronal Na+ channels.",{"v":378.1,"d":"378.10"},"18683-91-5",{"v":76,"d":"76.00"},{"v":201,"d":"201.00"},{"v":-1,"d":"-1.00"},-2.64,"https://www.selleckchem.com/products/ambroxol.html","C13H18Br2N2O","Expectorant","N/A","NC1=C(Br)C=C(Br)C=C1CNC2CCC(O)CC2",2.739,0,3,3]
["S5711","Deracoxib","a9","L4000-12","in 10mM DMSO","COX","Immunology & Inflammation","Deracoxib (SC-046) is a COX-2 inhibitor with >48-fold selectivity over COX-1. It also exhibits inhibitory activity against phosphodiesterase (Ki = 3.6 μM against human PDE4D3).",397.37,"169590-41-4",{"v":80,"d":"80.00"},201.32,"<1","N/A","http://selleckchem.com/products/deracoxib.html","C17H14F3N3O3S","free base","SC-046","COC1=C(F)C=C(C=C1)C2=CC(=N[N]2C3=CC=C(C=C3)[S](N)(=O)=O)C(F)F",3.642,4,1,5]
["S5714","lurasidone","b9","L4000-12","in 10mM DMSO","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Lurasidone (SM-13496) is a second-generation antipsychotic agent that exhibits full antagonism at dopamine D2 and serotonin 5-HT2A receptors with binding affinities Ki = 1 nM and Ki = 0.5 nM, respectively. It also has high affinity for serotonin 5-HT7 receptors (Ki = 0.5 nM), partial agonist activity at 5-HT1A receptors (Ki = 6.4 nM) and lacks affinity for histamine H1 and muscarinic M1 receptors.",492.68,"367514-87-2",{"v":7,"d":"7.00"},14.21,"<1","N/A","http://selleckchem.com/products/lurasidone.html","C28H36N4O2S","free base","SM-13496","O=C1C2C3CCC(C3)C2C(=O)N1CC4CCCCC4CN5CCN(CC5)C6=NSC7=CC=CC=C67",4.896,3,0,5]
["S5715","Atorvastatin","c9","L4000-12","in 10mM DMSO","Autophagy,HMG-CoA Reductase","Metabolism","Atorvastatin is a lipid lowering agent. It is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the rate-determining enzyme in cholesterol biosynthesis via the mevalonate pathway. Atorvastatin activates autophagy.",558.64,"134523-00-5",{"v":100,"d":"100.00"},179.01,"<1","N/A","http://www.selleckchem.com/products/atorvastatin.html","C33H35FN2O5","Free Base","N/A","CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C([N]1CCC(O)CC(O)CC(O)=O)C3=CC=C(F)C=C3)C4=CC=CC=C4",5.555,2,3,12]
["S5718","Acrivastine","d9","L4000-12","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Acrivastine(BW825C) is an antihistamine medicine that relieves the symptoms of allergies.",348.44,"87848-99-5",{"v":10,"d":"10.00"},{"v":28.7,"d":"28.70"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/acrivastine.html","C22H24N2O2","Free Base","BW825C","CC1=CC=C(C=C1)C(=C\\CN2CCCC2)/C3=CC=CC(=N3)\\C=C\\C(O)=O",1.566,2,0,6]
["S5723","Carvedilol EP IMpurity E","e9","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Carvedilol is a nonselective beta blocker/alpha-1 blocker and used in management of congestive heart failure (CHF).",203.67,"64464-07-9",{"v":40,"d":"40.00"},{"v":196.4,"d":"196.40"},{"v":-1,"d":"-1.00"},-4.91,"https://www.selleckchem.com/products/carvedilol-ep-impurity-e.html","C9H14ClNO2","free base","Carvedilol USP E, Carvedilol Impurity E","Cl.COC1=C(OCCN)C=CC=C1",{"v":1.35,"d":"1.350"},2,1,4]
["S5725","Pempidine","f9","L4000-12","in 10mM DMSO","Others","Others","Pempidine (Pyrilene, Perolysen, 1,2,2,6,6-Pentamethylpiperidine) is a long-acting ganglion-blocking compound.",155.28,"79-55-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",{"v":10,"d":"10.00"},"N/A",{"v":0,"d":"0.00"},"https://www.selleckchem.com/products/pempidine.html","C10H21N","free base","Pyrilene; Perolysen; 1,2,2,6,6-Pentamethylpiperidine","CN1C(C)(C)CCCC1(C)C",2.402,0,0,0]
["S5727","Tetryzoline","g9","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Tetryzoline (Tetrahydrozoline) is an alpha-adrenergic agonist used in some over-the-counter eye drops and nasal sprays.",200.28,"84-22-0",{"v":40,"d":"40.00"},199.72,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/tetryzoline.html","C13H16N2","Free Base","Tetrahydrozoline","C1CC(C2=NCCN2)C3=C(C1)C=CC=C3",2.185,1,1,1]
["S5734","Midodrine hydrochloride","h9","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Midodrine hydrochloride is the hydrochloride salt form of midodrine, an adrenergic alpha-1 agonist used as a vasopressor.",290.74,"43218-56-0",{"v":58,"d":"58.00"},199.49,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/midodrine-hydrochloride.html","C12H19ClN2O4","Hydrochloride","N/A","Cl.COC1=CC=C(OC)C(=C1)C(O)CNC(=O)CN",-0.166,3,3,6]
["S5735","Midodrine","a10","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Midodrine belongs to the class of medications known as vasopressors. It is an adrenergic alpha-1 agonist.",254.28,"42794-76-3",{"v":51,"d":"51.00"},200.57,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/midodrine.html","C12H18N2O4","Free Base","N/A","COC1=CC=C(OC)C(=C1)C(O)CNC(=O)CN",-0.548,3,3,6]
["S5739","Nebivolol","b10","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Nebivolol (Bystolic,R 065824) is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and also for left ventricular failure.",405.43,"118457-14-0",{"v":88,"d":"88.00"},217.05,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/nebivolol.html","C22H25F2NO4","Free Base","Bystolic,R 065824","OC(CNCC(O)C1CCC2=CC(=CC=C2O1)F)C3CCC4=C(O3)C=CC(=C4)F",3.557,2,3,6]
["S5740","Palonosetron","c10","L4000-12","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Palonosetron (RS25259, RS 25259 197) is a 5-HT3 antagonist with Ki value of 0.17 nM. It is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).",296.41,"135729-61-2",{"v":59,"d":"59.00"},199.05,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/palonosetron.html","C19H24N2O","Free Base","RS25259, RS 25259 197","O=C1N(CC2CCCC3=C2C1=CC=C3)C4CN5CCC4CC5",2.745,1,0,1]
["S5741","Quetiapine","d10","L4000-12","in 10mM DMSO","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Quetiapine(ICI204636) is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.Quetiapine is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine is a dopamine receptor antagonist with a pIC50 of 6.33 for human D2 receptor. Quetiapine have moderate to high affinity for the human D2, HT1A, 5-HT2A, 5-HT2C receptor with pKis of 7.23, 5.74, 7.54, 5.55.",383.51,"111974-69-7",{"v":77,"d":"77.00"},200.78,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/quetiapine.html","C21H25N3O2S","Free Base","ICI204636","OCCOCCN1CCN(CC1)C2=NC3=CC=CC=C3SC4=C2C=CC=C4",2.656,2,1,6]
["S5742","Deferoxamine mesylate (Ba 33112)","e10","L4000-12","in 10mM DMSO","Autophagy,Beta Amyloid,Ferroptosis,HIF","Autophagy","Deferoxamine mesylate (Ba 33112, Desferrioxamine B, DFOM, NSC 644468) is the mesylate salt of Deferoxamine, which forms iron complexes and is used as a chelating agent. Deferoxamine is a ferroptosis inhibitor that stabilizes HIF-1α expression and improves HIF-1α transactivity in hypoxic and hyperglycemic states in vitro. Deferoxamine decreases beta-amyloid (Aβ) deposition and induces autophagy.Please do not prepare stock solutions with normal saline or PBS, as precipitation may occur.",656.79,"138-14-7",{"v":100,"d":"100.00"},152.26,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/deferoxamine-mesylate.html","C26H52N6O11S","mesylate","Desferrioxamine B, DFOM, NSC 644468","CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN.C[S](O)(=O)=O",-1.304,5,3,23]
["S5747","Morantel tartrate","f10","L4000-12","in 10mM DMSO","AChR","Neuronal Signaling","Morantel (CP-12009-18, UK 296418) is a positive allosteric modulator of neuronal nicotinic acetylcholine receptors (nAChRs).",370.42,"26155-31-7",{"v":74,"d":"74.00"},199.77,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/morantel-tartrate.html","C16H22N2O6S","tartrate","CP-12009-18 tartrate, UK 296418 tartrate","CN1CCCN=C1/C=C/C2=C(C)C=CS2.OC(C(O)C(O)=O)C(O)=O",0.629,3,2,5]
["S5749","Chlorpromazine","g10","L4000-12","in 10mM DMSO","5-HT Receptor,Dopamine Receptor,Potassium Channel,Sodium Channel","Neuronal Signaling","Chlorpromazine (CPZ) is a low-potency typical antipsychotic agent that is used to treat psychotic disorders such as schizophrenia. Chlorpromazine (CPZ) inhibits 5-HT(2A) receptor and dopamine D2 in vitro. Chlorpromazine (CPZ) also inhibits sodium channel and blocks HERG potassium channels with IC50 of 21.6 μM.",318.86,"50-53-3",{"v":64,"d":"64.00"},200.72,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/chlorpromazine.html","C17H19ClN2S","Free Base","CPZ","CN(C)CCCN1C2=C(SC3=C1C=C(Cl)C=C3)C=CC=C2",4.739,0,0,4]
["S5750","DL-Norepinephrine hydrochloride","h10","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Norepinephrine (noradrenaline) is the neurotransmitter at most sympathetic neuroeffector junctions and has pharmacologic effects on both α1 and β1 adrenoceptors.",205.64,"55-27-6",{"v":41,"d":"41.00"},199.38,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/dl-norepinephrine-hydrochloride.html","C8H12ClNO3","hydrochloride","noradrenaline hydrochloride","Cl.NCC(O)C1=CC(=C(O)C=C1)O",0.323,0,4,2]
["S5755","Methyl Eugenol","a11","L4000-12","in 10mM DMSO","Others","Others","Methyl eugenol (4-allylveratrole, eugenyl methyl ether, O-methyleugenol), as a constituent in leaves, fruits, stems, and/or roots, is used as a flavoring agent, as a fragrance and as an anesthetic in rodents.,",178.23,"93-15-2","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/methyl-eugenol.html","C11H14O2","Free Base","4-allylveratrole, eugenyl methyl ether, O-methyleugenol","COC1=C(OC)C=C(CC=C)C=C1",2.805,2,0,4]
["S5766","Alfuzosin","b11","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Alfuzosin(SL 77499), a quinazoline derivative, is a selective and competitive α1-adrenoceptor antagonist.",389.45,"81403-80-7",{"v":78,"d":"78.00"},200.28,"<1","N/A","http://www.selleckchem.com/products/alfuzosin.html","C19H27N5O4","Free Base","SL 77499","COC1=CC2=NC(=NC(=C2C=C1OC)N)N(C)CCCNC(=O)C3CCCO3",1.418,6,2,8]
["S5768","Fenoterol hydrobromide","c11","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Fenoterol hydrobromide (Phenoterol) is the the hydrobromide salt of fenoterol, a β2 adrenoreceptor agonist with bronchodilator activity.",384.26,"1944-12-3",{"v":77,"d":"77.00"},200.39,{"v":11,"d":"11.00"},28.63,"http://www.selleckchem.com/products/fenoterol-hydrobromide.html","C17H22BrNO4","hydrobromide","Phenoterol hydrobromide","Br.CC(CC1=CC=C(O)C=C1)NCC(O)C2=CC(=CC(=C2)O)O",2.904,0,5,6]
["S5769","Fenoterol","d11","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Fenoterol (Phenoterol) is a β2 adrenoreceptor agonist with bronchodilator activity.",303.35,"13392-18-2",{"v":61,"d":"61.00"},201.09,"<1","N/A","http://www.selleckchem.com/products/fenoterol.html","C17H21NO4","Free Base","Phenoterol","CC(CC1=CC=C(O)C=C1)NCC(O)C2=CC(=CC(=C2)O)O",2.413,0,5,6]
["S5778","Esmolol","e11","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Esmolol is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages.",295.37,"81147-92-4",{"v":59,"d":"59.00"},199.75,{"v":59,"d":"59.00"},199.75,"http://www.selleckchem.com/products/esmolol.html","C16H25NO4","Free Base","N/A","COC(=O)CCC1=CC=C(OCC(O)CNC(C)C)C=C1",1.978,3,2,10]
["S5780","Prazosin","f11","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Prazosin is an α1-blocker that acts as an inverse agonist at alpha-1 adrenergic receptors. It is used to treat hypertension.",{"v":383.4,"d":"383.40"},"19216-56-9",{"v":77,"d":"77.00"},200.83,{"v":1,"d":"1.00"},2.61,"http://www.selleckchem.com/products/prazosin.html","C19H21N5O4","Free Base","N/A","COC1=CC2=NC(=NC(=C2C=C1OC)N)N3CCN(CC3)C(=O)C4=CC=CO4",2.107,6,1,4]
["S5782","Doxazosin","g11","L4000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Doxazosin(UK 33274) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.",451.48,"74191-85-8",{"v":31,"d":"31.00"},68.66,{"v":1,"d":"1.00"},2.21,"http://www.selleckchem.com/products/doxazosin.html","C23H25N5O5","Free Base","UK 33274","COC1=CC2=C(C=C1OC)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=C(O4)C=CC=C5)N",2.485,7,1,4]
["S5783","Montelukast","h11","L4000-12","in 10mM DMSO","LTR","Immunology & Inflammation","Montelukast(MK0476) is a leukotriene receptor antagonist used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.",586.18,"158966-92-8",{"v":100,"d":"100.00"},{"v":170.6,"d":"170.60"},{"v":1,"d":"1.00"},1.71,"http://www.selleckchem.com/products/montelukast.html","C35H36ClNO3S","Free Base","MK0476","CC(C)(O)C1=CC=CC=C1CCC(SCC2(CC2)CC(O)=O)C3=CC=CC(=C3)\\C=C\\C4=CC=C5C=CC(=CC5=N4)Cl",8.284,2,0,12]
["S5787","Dronedarone","a2","L4000-13","in 10mM DMSO","Adrenergic Receptor","Transmembrane Transporters","Dronedarone (SR33589) is a derivative of amiodarone which is classified as a Class III antiarrhythmic agent. It shows rate-dependent inhibition of the rapid Na+ current, inhibits α and β-adrenergic receptors like Class II agents, exhibits blockade of K+ outward currents as the main mechanism of action of Class III, and effectively block slow Ca2+ inward currents (Class IV).",556.76,"141626-36-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/dronedarone.html","C31H44N2O5S","Free Base","SR33589","CCCCN(CCCC)CCCOC1=CC=C(C=C1)C(=O)C2=C(CCCC)OC3=C2C=C(N[S](C)(=O)=O)C=C3",7.015,5,1,18]
["S5795","Rasagiline","b2","L4000-13","in 10mM DMSO","MAO","Metabolism","Rasagiline (TVP-1012) is a novel selective and irreversible MAO-B propargylamine inhibitor with in vitro IC50s of 4.43 nM and 412 nM for MAO-B and MAO-A, respectively.",171.24,"136236-51-6",{"v":34,"d":"34.00"},198.55,{"v":4,"d":"4.00"},23.36,"http://www.selleckchem.com/products/rasagiline.html","C12H13N","Free Base","TVP-1012","C#CCNC1CCC2=C1C=CC=C2",3.119,0,1,2]
["S5796","Vanoxerine dihydrochloride","c2","L4000-13","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Vanoxerine (GBR-12909) is a potent and selective inhibitor of the presynaptic dopamine uptake complex.",523.49,"67469-78-7",{"v":17,"d":"17.00"},32.47,{"v":5,"d":"5.00"},9.55,"http://www.selleck.cn/products/vanoxerine-dihydrochloride.html","C28H34Cl2F2N2O","dihydrochloride","GBR-12909","Cl.Cl.FC1=CC=C(C=C1)C(OCCN2CCN(CCCC3=CC=CC=C3)CC2)C4=CC=C(F)C=C4",6.878,1,0,10]
["S5802","Alprenolol hydrochloride","d2","L4000-13","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Alprenolol hydrochloride is the hydrochloride salt form of alprenolol, which is an beta adrenergic receptorantagonist and is used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.",285.81,"13707-88-5",{"v":57,"d":"57.00"},199.43,{"v":57,"d":"57.00"},199.43,"http://www.selleckchem.com/products/alprenolol-hydrochloride.html","C15H24ClNO2","Hydrochloride","N/A","Cl.CC(C)NCC(O)COC1=CC=CC=C1CC=C",3.021,1,2,8]
["S5803","Alrestatin","e2","L4000-13","in 10mM DMSO","Aldose Reductase","Metabolism","Alrestatin is an inhibitor of aldose reductase which is involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy.",255.23,"51411-04-2",{"v":51,"d":"51.00"},199.82,"<1","N/A","http://www.selleckchem.com/products/alrestatin.html","C14H9NO4","Free Base","N/A","OC(=O)CN1C(=O)C2=C3C(=CC=C2)C=CC=C3C1=O",1.252,3,0,2]
["S5804","N-Acetylcysteine amide","f2","L4000-13","in 10mM DMSO","HIF,Immunology & Inflammation related,NF-κB,ROS","Immunology & Inflammation","N-acetylcysteine amide is a membrane penetrating antioxidant with anti-inflamatory activity through regulation of activation of NF-κB and HIF-1α as well as modulation of ROS.",162.21,"38520-57-9",{"v":32,"d":"32.00"},197.28,{"v":32,"d":"32.00"},197.28,"http://www.selleckchem.com/products/n-acetylcysteine-amide.html","C5H10N2O2S","Free Base","N/A","CC(=O)NC(CS)C(N)=O",-1.205,2,2,3]
["S5805","Allopregnanolone","g2","L4000-13","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Allopregnanolone, a neurosteroid synthesized from progesterone in brain, acts as a highly potent positive allosteric modulator of the GABAA receptor.",318.49,"516-54-1",{"v":64,"d":"64.00"},200.95,"<1","N/A","http://www.selleckchem.com/products/allopregnanolone.html","C21H34O2","Free Base","N/A","CC(=O)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C",3.874,1,1,1]
["S5814","cariporide","h2","L4000-13","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Cariporide is a selective and potent inhibitor of NHE1 with an IC50 of 30 nM for hNHE1 in CHO-K1 cells.",283.35,"159138-80-4",{"v":87,"d":"87.00"},307.04,"<1","N/A","http://www.selleckchem.com/products/cariporide.html","C12H17N3O3S","Free Base","HOE-642","CC(C)C1=CC=C(C=C1[S](C)(=O)=O)C(=O)NC(N)=N",1.386,3,2,4]
["S5821","Linoleic acid","a3","L4000-13","in 10mM DMSO","Others","Others","Linoleic acid (9,12-octadecadienoic acid) is an essential fatty acid used in the biosynthesis of arachidonic acid and found in the lipids of cell membranes.,",280.45,"60-33-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/linoleic-acid.html","C18H32O2","Free Base","9,12-octadecadienoic acid","CCCCC/C=C\\C\\C=C/CCCCCCCC(O)=O",6.416,1,0,14]
["S5829","Monomyristin","b3","L4000-13","in 10mM DMSO","Fungal","Microbiology","Monomyristin (Glyceryl myristate, 2,3-Dihydroxypropyl tetradecanoate), a monoacylglyceride, shows high antibacterial and antifungal activities.",302.45,"589-68-4",{"v":60,"d":"60.00"},198.38,{"v":1,"d":"1.00"},3.31,"http://www.selleckchem.com/products/monomyristin.html","C17H34O4","Free Base","Glyceryl myristate; 2,3-Dihydroxypropyl tetradecanoate","CCCCCCCCCCCCCC(=O)OCC(O)CO",4.656,2,2,16]
["S5836","IBMX","c3","L4000-13","in 10mM DMSO","PDE","Metabolism","IBMX (Isobutylmethylxanthine, 1-Methyl-3-Isobutylxanthine) is a nonspecific inhibitor of phosphodiesterase (PDE) with IC50 values of 6.5±1.2, 26.3±3.9 and 31.7±5.3 μM for PDE3, 4 and 5 respectively. It may enhance the intracellular cAMP levels and also acts as an adenosine (A1) receptor antagonist.",222.24,"28822-58-4",{"v":44,"d":"44.00"},197.98,{"v":1,"d":"1.00"},{"v":4.5,"d":"4.50"},"http://www.selleckchem.com/products/ibmx.html","C10H14N4O2","Free Base","Isobutylmethylxanthine, 1-Methyl-3-Isobutylxanthine","CC(C)CN1C(=O)N(C)C(=O)C2=C1[NH]C=N2",0.608,3,1,2]
["S5842","Cabergoline","d3","L4000-13","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Cabergoline (FCE-21336), an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor.",{"v":451.6,"d":"451.60"},"81409-90-7",{"v":90,"d":"90.00"},199.29,{"v":1,"d":"1.00"},2.21,"http://www.selleckchem.com/products/cabergoline.html","C26H37N5O2","Free Base","FCE-21336","CCNC(=O)N(CCCN(C)C)C(=O)C1CC2C(CC3=C[NH]C4=C3C2=CC=C4)N(CC=C)C1",3.036,2,2,8]
["S5843","Cinitapride Hydrogen Tartrate","e3","L4000-13","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors",552.57,"1207859-16-2",{"v":59,"d":"59.00"},106.77,{"v":5,"d":"5.00"},9.05,"http://www.selleckchem.com/products/cinitapride-hydrogen-tartrate.html","C25H36N4O10","Hydrogen Tartrate","N/A","CCOC1=CC(=C(C=C1C(=O)NC2CCN(CC2)CC3CCC=CC3)[N+]([O-])=O)N.OC(C(O)C(O)=O)C(O)=O",-2.325,4,4,10]
["S5848","Frovatriptan Succinate","f3","L4000-13","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Frovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.",361.39,"158930-09-7",{"v":72,"d":"72.00"},199.23,{"v":72,"d":"72.00"},199.23,"http://www.selleck.cn/products/frovatriptan-succinate.html","C18H23N3O5","Succinate","SB 209509 Succinate,VML 251 Succinate","CNC1CCC2=C(C1)C3=C([NH]2)C=CC(=C3)C(N)=O.OC(=O)CCC(O)=O",{"v":-1.65,"d":"-1.650"},3,3,5]
["S5857","Trazodone","g3","L4000-13","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Trazodone (AF-1161) is a 5-HT 2A/2C receptor antagonist that is used as an antidepressant for treating major depressive disorder and anxiety disorders.",371.86,"19794-93-5",{"v":45,"d":"45.00"},121.01,"<1","N/A","http://www.selleck.cn/products/trazodone.html","C19H22ClN5O","Free Base","AF-1161","ClC1=CC(=CC=C1)N2CCN(CCCN3N=C4C=CC=CN4C3=O)CC2",2.418,2,0,5]
["S5858","Vilazodone","h3","L4000-13","in 10mM DMSO","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Vilazodone (EMD-68843, SB-659746A) is a novel antidepressant having a selective serotonin (5-HT) reuptake inhibitory and 5-HT1A receptor partial agonist activity. The affinity of vilazodone is much higher in the 5-HT reuptake site (Ki=0.1 nM) than in norepinephrine (Ki=56 nM) and dopamine (Ki=37 nM) sites.",441.52,"163521-12-8",{"v":88,"d":"88.00"},199.31,{"v":1,"d":"1.00"},2.26,"https://www.selleckchem.com/products/vilazodone.html","C26H27N5O2","Free Base","EMD-68843, SB-659746A","NC(=O)C1=CC2=C(O1)C=CC(=C2)N3CCN(CCCCC4=C[NH]C5=C4C=C(C=C5)C#N)CC3",4.536,2,2,7]
["S5861","Lercanidipine","a4","L4000-13","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Lercanidipine is a vasoselective dihydropyridine calcium antagonist used for the treatment of essential hypertension.",611.73,"100427-26-7",{"v":55,"d":"55.00"},89.91,{"v":1,"d":"1.00"},1.63,"http://www.selleckchem.com/products/lercanidipine.html","C36H41N3O6","Free Base","N/A","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OC(C)(C)CN(C)CCC(C3=CC=CC=C3)C4=CC=CC=C4)C",6.132,4,1,14]
["S5862","Metoclopramide","b4","L4000-13","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Metoclopramide is a dopamine antagonist used for the treatment of nausea and vomiting.",{"v":299.8,"d":"299.80"},"364-62-5",{"v":60,"d":"60.00"},200.13,{"v":1,"d":"1.00"},3.34,"http://www.selleckchem.com/products/metoclopramide.html","C14H22ClN3O2","Free Base","N/A","CCN(CC)CCNC(=O)C1=C(OC)C=C(N)C(=C1)Cl",1.775,2,2,7]
["S5868","DL-Menthol","c4","L4000-13","in 10mM DMSO","Others","Others","DL-Menthol is a racemic mixture of D- and L-menthol. Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils.",156.27,"89-78-1",{"v":31,"d":"31.00"},198.37,{"v":31,"d":"31.00"},198.37,"http://www.selleck.cn/products/dl-menthol.html","C10H20O","Free Base","N/A","CC(C)C1CCC(C)CC1O",2.779,0,1,1]
["S5873","Scopolamine HBr trihydrate","d4","L4000-13","in 10mM DMSO","AChR","Neuronal Signaling","Scopolamine HBr is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55.3 nM.",438.31,"6533-68-2",{"v":88,"d":"88.00"},200.77,{"v":88,"d":"88.00"},200.77,"https://www.selleckchem.com/products/scopolamine-hbr-trihydrate.html","C17H28BrNO7","HBr trihydrate","N/A","O.O.O.Br.CN1C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",0.693,3,1,5]
["S5886","Hodostin","e4","L4000-13","in 10mM DMSO","AChR","Neuronal Signaling","Hodostin (Neostigmine methyl sulfate, Syntostigmin, Neostigmeth) is a reversible inhibitor of acetylcholinesterase (AChE), but can not cross the blood-brain barrier. It is used in the treatment of myasthenia gravis.",334.39,"51-60-5",{"v":67,"d":"67.00"},200.36,{"v":67,"d":"67.00"},200.36,"http://www.selleck.cn/products/hodostin.html","C13H22N2O6S","Free Base","Neostigmine methyl sulfate, Syntostigmin, Neostigmeth","CO[S]([O-])(=O)=O.CN(C)C(=O)OC1=CC(=CC=C1)[N+](C)(C)C",-2.302,3,0,4]
["S5900","Edrophonium chloride","f4","L4000-13","in 10mM DMSO","AChR","Metabolism","Edrophonium chloride is the chloride salt of edrophonium, which is a rapid-onset, short-acting, readily reversible inhibitor of acetylcholinesterase.",201.69,"116-38-1",{"v":40,"d":"40.00"},198.32,{"v":40,"d":"40.00"},198.32,"http://www.selleckchem.com/products/edrophonium-chloride.html","C10H16ClNO","chloride","N/A","[Cl-].CC[N+](C)(C)C1=CC=CC(=C1)O",-2.026,0,1,2]
["S5914","AK 7","g4","L4000-13","in 10mM DMSO","Sirtuin","Epigenetics","AK 7 is a brain-permeable selective SIRT2 inhibitor with an IC50 of 15.5 μM.",437.35,"420831-40-9",{"v":87,"d":"87.00"},198.93,"<1","N/A","http://www.selleckchem.com/products/ak-7.html","C19H21BrN2O3S","Free Base","N/A","BrC1=CC(=CC=C1)NC(=O)C2=CC=CC(=C2)[S](=O)(=O)N3CCCCCC3",3.853,3,1,4]
["S5921","Cyclopentolate Hydrochloride","h4","L4000-13","in 10mM DMSO","AChR","Neuronal Signaling","Cyclopentolate is an antagonist of muscarinic acetylcholine receptors with Ki values of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively.",327.85,"5870-29-1",{"v":66,"d":"66.00"},201.31,{"v":66,"d":"66.00"},201.31,"http://www.selleck.cn/products/cyclopentolate-hydrochloride.html","C17H26ClNO3","Hydrochloride","N/A","Cl.CN(C)CCOC(=O)C(C1=CC=CC=C1)C2(O)CCCC2",2.871,2,0,7]
["S5923","Celiprolol hydrochloride","a5","L4000-13","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Celiprolol is a β1-adrenoceptor antagonist with partial β2 agonist activity.",415.95,"57470-78-7",{"v":83,"d":"83.00"},199.54,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/celiprolol-hydrochloride.html","C20H34ClN3O4","hydrochloride","N/A","Cl.CCN(CC)C(=O)NC1=CC(=C(OCC(O)CNC(C)(C)C)C=C1)C(C)=O",1.978,3,3,10]
["S5925","Olodaterol hydrochloride","b5","L4000-13","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Olodaterol hydrochloride (BI-1744) is the hydrochloride salt form of Olodaterol, which is a long-acting beta2-adrenergic agonist.",{"v":422.9,"d":"422.90"},"869477-96-3",{"v":85,"d":"85.00"},200.99,{"v":85,"d":"85.00"},200.99,"http://www.selleckchem.com/products/olodaterol-hydrochloride.html","C21H27ClN2O5","hydrochloride","BI-1744 HCl","Cl.COC1=CC=C(CC(C)(C)NCC(O)C2=C3OCC(=O)NC3=CC(=C2)O)C=C1",2.257,3,4,7]
["S5926","Pitolisant hydrochloride","c5","L4000-13","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Pitolisant (Tiprolisant, BF-2649) acts as a high-affinity competitive antagonist (Ki=0.16 nM) and as an inverse agonist (EC50=1.5 nM) at the human histamine H3 receptor subtype.",332.31,"903576-44-3",{"v":66,"d":"66.00"},198.61,{"v":66,"d":"66.00"},198.61,"http://www.selleckchem.com/products/pitolisant-hydrochloride.html","C17H27Cl2NO","hydrochloride","Tiprolisant hydrochloride, BF-2649 HCl","Cl.ClC1=CC=C(CCCOCCCN2CCCCC2)C=C1",4.576,1,0,8]
["S5930","PNU 282987 HCl","d5","L4000-13","in 10mM DMSO","AChR","Metabolism","PNU 282987 is a potent agonist of α7-containing neuronal nicotinic acetylcholine receptors with Ki value of 26 nM for the rat receptor.",301.21,"123464-89-1",{"v":46,"d":"46.00"},152.72,{"v":11,"d":"11.00"},36.52,"https://www.selleckchem.com/products/pnu-282987-hcl.html","C14H18Cl2N2O","Free Base","N/A","Cl.ClC1=CC=C(C=C1)C(=O)NC2CN3CCC2CC3",{"v":2.62,"d":"2.620"},1,1,2]
["S5931","BQCA","e5","L4000-13","in 10mM DMSO","AChR","Metabolism","BQCA (benzylquinolone carboxylic acid) is a highly selective positive allosteric modulator of the M1 muscarinic acetylcholine receptor (mAChR).",309.32,"338747-41-4",{"v":13,"d":"13.00"},42.03,{"v":1,"d":"1.00"},3.23,"http://www.selleckchem.com/products/bqca.html","C18H15NO4","Free Base","benzylquinolone carboxylic acid","COC1=CC=C(CN2C=C(C(O)=O)C(=O)C3=CC=CC=C23)C=C1",2.723,3,0,4]
["S5932","BIA 10-2474","f5","L4000-13","in 10mM DMSO","FAAH","Metabolism","BIA 10-2474 is a novel fatty acid amide hydrolase (FAAH) inhibitor, with a potent inhibitory effect upon FAAH and prolonged action in vivo.",300.36,"1233855-46-3",{"v":4,"d":"4.00"},13.32,"<1","N/A","http://www.selleck.cn/products/bia-10-2474.html","C16H20N4O2","Free Base","N/A","CN(C1CCCCC1)C(=O)[N]2C=NC(=C2)C3=CC=C[N+](=C3)[O-]",1.719,2,0,2]
["S5935","Alvimopan","g5","L4000-13","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","Alvimopan (LY 246736, ADL 8-2698) is a potent, relatively nonselective opioid antagonist with Ki values of 0.77, 4.4, and 40 nM for the μ, δ, and κ opioid receptors, respectively, displaying >100-fold selectivity over other aminergic G-protein-coupled receptors.",424.53,"156053-89-3",{"v":85,"d":"85.00"},200.22,{"v":1,"d":"1.00"},2.36,"http://www.selleckchem.com/products/alvimopan.html","C25H32N2O4","Free Base","LY 246736, ADL 8-2698","CC1CN(CCC1(C)C2=CC=CC(=C2)O)CC(CC3=CC=CC=C3)C(=O)NCC(O)=O",{"v":0.51,"d":"0.510"},2,2,8]
["S5940","Bepotastine","h5","L4000-13","in 10mM DMSO","COVID-19,Histamine Receptor","Neuronal Signaling","Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor that is indicated in allergic rhinitis, urticaria, and pruritus associated with skin disease.",388.89,"125602-71-3",{"v":78,"d":"78.00"},200.57,{"v":78,"d":"78.00"},200.57,"http://www.selleck.cn/products/bepotastine.html","C21H25ClN2O3","Free Base","N/A","OC(=O)CCCN1CCC(CC1)OC(C2=CC=C(Cl)C=C2)C3=CC=CC=N3",0.208,3,0,8]
["S5950","Fingolimod","a6","L4000-13","in 10mM DMSO","S1P Receptor","Neuronal Signaling","Fingolimod (FTY-720A, FTY-720) is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis.",307.47,"162359-55-9",{"v":13,"d":"13.00"},42.28,{"v":1,"d":"1.00"},3.25,"https://www.selleckchem.com/products/fingolimod.html","C19H33NO2","Free Base","FTY-720A, FTY-720","CCCCCCCCC1=CC=C(CCC(N)(CO)CO)C=C1",4.198,0,3,12]
["S6002","Disufenton sodium","b6","L4000-13","in 10mM DMSO","Others","Others","Disufenton Sodium (NXY-059, Cerovive) is a novel nitrone, shows efficacious neuroprotective effects. Phase 3.",381.33,"168021-79-2",{"v":76,"d":"76.00"},{"v":199.3,"d":"199.30"},{"v":76,"d":"76.00"},{"v":199.3,"d":"199.30"},"http://selleckchem.com/products/NXY-059.html","C11H13NNa2O7S2","Disodium salt","NXY-059, Cerovive","[Na+].[Na+].CC(C)(C)/[N+]([O-])=C/C1=CC=C(C=C1[S]([O-])(=O)=O)[S]([O-])(=O)=O",-3.972,0,0,4]
["S6008","p-Hydroxybenzaldehyde","c6","L4000-13","in 10mM DMSO","GABA Receptor","Neuronal Signaling","p-Hydroxybenzaldehyde (4-Hydroxybenzaldehyde, 4-Formylphenol, p-Formylphenol), which can be found in the orchids Gastrodia elata, Galeola faberi and vanilla, is a hydroxybenzaldehyde that reacts with NAD+ and H2O to produce 4-hydroxybenzoate, NADH, and 2 protons. p-Hydroxybenzaldehyde at 101.7 μM can significantly reduce the GABA-induced chloride current of GABAA receptors(α1β2γ2S subtype) expressed.",122.12,"123-08-0",{"v":24,"d":"24.00"},196.53,"N/A","N/A","http://www.selleck.cn/products/p-hydroxybenzaldehyde.html","C7H6O2","free base","4-Hydroxybenzaldehyde, 4-Formylphenol, p-Formylphenol","OC1=CC=C(C=O)C=C1",1.347,1,1,1]
["S6058","β-Caryophyllene","d6","L4000-13","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","β-Caryophyllene is a natural bicyclic sesquiterpene that is a constituent of many essential oils. It acts as a non-steroidal anti-inflammatory drug, a fragrance and a metabolite.",204.35,"87-44-5","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleck.cn/products/caryophyllene.html","C15H24","free base","N/A","CC/1=C\\CCC(=C)C2CC(C)(C)C2CC1",4.753,0,0,0]
["S6073","Diclofenac acid","e6","L4000-13","in 10mM DMSO","COX,Immunology & Inflammation related","Immunology & Inflammation","Diclofenac acid is a nonsteroidal anti-inflammatory drug that has analgesic, anti-inflammatory, and antipyretic properties, and has been shown to be effective in treating a variety of acute and chronic pain and inflammatory conditions. It inhibits cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) with relative equipotency.",296.15,"15307-86-5",{"v":59,"d":"59.00"},199.22,"N/A","N/A","http://www.selleck.cn/products/diclofenac-acid.html","C14H11Cl2NO2","free base","N/A","OC(=O)CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1",4.373,1,1,4]
["S6083","DL-Dopa","f6","L4000-13","in 10mM DMSO","Others","Others","DL-Dopa (3,4-Dihydroxy-DL-phenylalanine) is an immediate precursor of dopamine.",197.19,"63-84-3",{"v":3,"d":"3.00"},15.21,"N/A","N/A","http://www.selleck.cn/products/dl-dopa.html","C9H11NO4","free base","3,4-Dihydroxy-DL-phenylalanine","NC(CC1=CC(=C(O)C=C1)O)C(O)=O",-2.089,1,3,3]
["S6094","Imidazole-4(5)-acetic Acid Hydrochloride","g6","L4000-13","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Imidazole-4(5)-acetic Acid Hydrochloride is a competitive antagonist at GABAC receptors.",162.57,"3251-69-2",{"v":10,"d":"10.00"},61.51,"N/A","N/A","http://www.selleck.cn/products/imidazole-4-5-acetic-acid-hydrochloride.html","C5H7ClN2O2","Hydrochloride","N/A","Cl.OC(=O)CC1=C[NH]C=N1",0.192,2,1,2]
["S6122","Cyclohexanecarboxamide","h6","L4000-13","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Cyclohexanecarboxamide (Ethyl menthane carboxamide, WS3, Hexahydrobenzamide) is a cooling agent and an agonist at TRPM8 receptors (EC50 = 3.7 μM).",211.34,"39711-79-0",{"v":42,"d":"42.00"},198.73,{"v":1,"d":"1.00"},4.73,"https://www.selleckchem.com/products/cyclohexanecarboxamide.html","C13H25NO","Free Base","Ethyl menthane carboxamide, WS3, N-Ethyl-5-methyl-2-(1-methylethyl)-cyclohexanecarboxamide, Hexahydrobenzamide","CCNC(=O)C1CC(C)CCC1C(C)C",{"v":3.06,"d":"3.060"},1,1,3]
["S6172","Brucine sulfate heptahydrate","a7","L4000-13","in 10mM DMSO","GlyR","Transmembrane Transporters","Brucine is an alkaloid that acts as an antagonist at glycine receptors and paralyzes inhibitory neurons.",1013.11,"60583-39-3",202.62,{"v":200,"d":"200.00"},"N/A","N/A","http://www.selleck.cn/products/brucine-sulfate-heptahydrate.html","C46H68N4O19S","heptahydrate","N/A","O.O.O.O.O.O.O.COC1=CC2=C(C=C1OC)C34CCN5CC6=CCOC7CC(=O)N2C3C7C6CC45.COC8=CC9=C(C=C8OC)C%10%11CCN%12CC%13=CCOC%14CC(=O)N9C%10C%14C%13CC%11%12.O[S](O)(=O)=O",0.168,8,0,4]
["S6221","Methyl cinnamate","b7","L4000-13","in 10mM DMSO","AMPK,CaMK,Tyrosinase","Proteases","Methyl cinnamate, an active component of Zanthoxylum armatum, is a widely used natural flavor compound with antimicrobial and tyrosinase inhibitor activities. Methyl Cinnamate Inhibits Adipocyte Differentiation via Activation of the CaMKK2--AMPK Pathway in 3T3-L1 Preadipocytes.",162.19,"103-26-4",32.44,{"v":200,"d":"200.00"},"N/A","N/A","http://www.selleck.cn/products/methyl-cinnamate.html","C10H10O2","free base","N/A","COC(=O)/C=C/C1=CC=CC=C1",2.153,2,0,3]
["S6228","Indole-2-carboxylic acid","c7","L4000-13","in 10mM DMSO","Lipoxygenase","Metabolism","Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation.",161.16,"1477-50-5",32.23,{"v":200,"d":"200.00"},"N/A","N/A","http://www.selleck.cn/products/indole-2-carboxylic-acid.html","C9H7NO2","free base","N/A","OC(=O)C1=CC2=C([NH]1)C=CC=C2",2.044,1,1,1]
["S6324","5-Methoxytryptamine","d7","L4000-13","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","5-Methoxytryptamine (Mexamine, Methoxytryptamine) is a tryptamine derivative that acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors.",190.24,"608-07-1",38.05,{"v":200,"d":"200.00"},"N/A","N/A","http://www.selleck.cn/products/5-methoxytryptamine.html","C11H14N2O","free base","Mexamine, Methoxytryptamine","COC1=CC2=C([NH]C=C2CCN)C=C1",1.534,1,2,3]
["S6407","Tulobuterol hydrochloride","e7","L4000-13","in 10mM DMSO","Androgen Receptor","Neuronal Signaling","Tulobuterol is a long-acting β2-adrenergic receptor agonist that has bronchodilatory, anti-inflammatory, and antiviral activities.",264.19,"56776-01-3",{"v":53,"d":"53.00"},200.61,{"v":53,"d":"53.00"},200.61,"http://www.selleck.cn/products/tulobuterol-hydrochloride.html","C12H19Cl2NO","hydrochloride","N/A","Cl.CC(C)(C)NCC(O)C1=C(Cl)C=CC=C1",2.834,0,2,4]
["S6409","Zucapsaicin","f7","L4000-13","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Zucapsaicin, the cis-isomer of capsaicin, is a topical analgesic used to treat osteoarthritis of the knee and other neuropathic pain. It is also a TRPV-1 modulator.",305.41,"25775-90-0",{"v":61,"d":"61.00"},199.73,"<1","N/A","http://www.selleck.cn/products/zucapsaicin.html","C18H27NO3","Free Base","N/A","COC1=C(O)C=CC(=C1)CNC(=O)CCCC\\C=C/C(C)C",{"v":3.91,"d":"3.910"},2,2,9]
["S6410","Clemizole","g7","L4000-13","in 10mM DMSO","Dopamine Receptor,TRP Channel","Neuronal Signaling","Clemizole, a first-generation histamine receptor (H1) antagonist, is a potent inhibitor of behavioural and electrographic seizure activity. It has a potential therapeutic effect on hepatitis C infection and also potently inhibits TRPC5 ion channels.",325.84,"442-52-4",{"v":65,"d":"65.00"},199.48,{"v":-1,"d":"-1.00"},"N/A","http://www.selleck.cn/products/clemizole.html","C19H20ClN3","Free Base","N/A","ClC1=CC=C(C[N]2C(=NC3=C2C=CC=C3)CN4CCCC4)C=C1",4.527,1,0,4]
["S6412","Altiratinib","h7","L4000-13","in 10mM DMSO","c-Met,Tie-2,Trk receptor,VEGFR","Protein Tyrosine Kinase","Altiratinib (DCC-2701) is a potent single-digit nanomolar inhibitor of TRK, Met (c-Met), TIE2, and VEGFR2 kinases with IC50 vaules of 0.9 nM, 4.6 nM, and 0.8 nM for TRKA, B, and C, respectively. It inhibits Met (c-Met) and Met (c-Met) mutant with IC50 values in the range of 0.3-6 nM.",510.46,"1345847-93-9",{"v":100,"d":"100.00"},{"v":195.9,"d":"195.90"},"<1","N/A","http://www.selleck.cn/products/altiratinib.html","C26H21F3N4O4","free base","DCC-2701","FC1=CC=C(NC(=O)C2(CC2)C(=O)NC3=C(F)C=C(OC4=CC(=NC=C4)NC(=O)C5CC5)C(=C3)F)C=C1",3.867,5,3,8]
["S6415","Azeliragon (TTP488)","a8","L4000-13","in 10mM DMSO","Others","Others","Azeliragon (TTP488, PF-04494700) is an orally bioavailable small molecule that inhibits the receptor for advanced glycation endproducts (RAGE), which is an immunoglobulin-like cell surface receptor overexpressed in brain tissues of patients with AD.",532.12,"603148-36-3",{"v":100,"d":"100.00"},187.93,"<1","N/A","http://www.selleck.cn/products/azeliragon.html","C32H38ClN3O2","Free Base","PF-04494700","CCCCC1=NC(=C[N]1C2=CC=C(OC3=CC=C(Cl)C=C3)C=C2)C4=CC=C(OCCCN(CC)CC)C=C4",8.393,3,0,14]
["S6416","JNJ 31020028","b8","L4000-13","in 10mM DMSO","NPY receptor","GPCR & G Protein","JNJ 31020028 is a novel neuropeptide Y Y2 receptor antagonist which bound with high affinity with human and rat Y2 receptor (pIC50=8.07±0.05 for human Y2 receptor, and pIC50=8.22±0.06 for rat Y2 receptor) and >100-fold selective versus human Y1, Y4, and Y5 receptors.",565.68,"1094873-14-9",{"v":100,"d":"100.00"},176.78,"<1","N/A","https://www.selleckchem.com/products/jnj-31020028.html","C34H36FN5O2","Free Base","N/A","CCN(CC)C(=O)C(N1CCN(CC1)C2=CC=C(NC(=O)C3=CC=CC=C3C4=CC=CN=C4)C=C2F)C5=CC=CC=C5",4.989,3,1,9]
["S6422","Lazabemide","c8","L4000-13","in 10mM DMSO","MAO","Metabolism","Lazabemide (Ro 19-6327) is a reversible and selective inhibitor of monoamine oxidase B (MAO-B) with Ki value of 7.9 nM.",{"v":236.1,"d":"236.10"},"103878-83-7",{"v":40,"d":"40.00"},169.42,{"v":40,"d":"40.00"},169.42,"http://www.selleck.cn/products/lazabemide.html","C8H11Cl2N3O","Free Base","Ro 19-6327","Cl.NCCNC(=O)C1=CC=C(Cl)C=N1",0.533,2,2,3]
["S6432","Cevimeline HCl hemihydrate","d8","L4000-13","in 10mM DMSO","AChR","Metabolism","Cevimeline HCl hemihydrate(AF 102B, SNI 2011, SNK 508) is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3.",244.78,"153504-70-2",{"v":40,"d":"40.00"},169.66,{"v":40,"d":"40.00"},169.66,"https://www.selleckchem.com/products/cevimeline.html","C10H18ClNOS.1/2H2O","HCl hemihydrate","AF 102B, SNI 2011, SNK 508","Cl.CC1OC2(CS1)CN3CCC2CC3",2.151,1,0,0]
["S6435","Mequitazine","e8","L4000-13","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Mequitazine (LM-209) is a histamine H1 antagonist which competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract.",322.47,"29216-28-2",{"v":32,"d":"32.00"},99.23,"<1","N/A","http://www.selleck.cn/products/mequitazine.html","C20H22N2S","Free Base","LM-209","C1CN2CCC1C(C2)CN3C4=C(SC5=C3C=CC=C5)C=CC=C4",4.409,0,0,2]
["S6447","Carazolol","f8","L4000-13","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Carazolol is a non-specific β-adrenergic receptor blocking agent and binds to β receptors irreversibly.",298.38,"57775-29-8",{"v":60,"d":"60.00"},201.09,"<1","N/A","http://www.selleck.cn/products/carazolol.html","C18H22N2O2","Free Base","N/A","CC(C)NCC(O)COC1=CC=CC2=C1C3=C([NH]2)C=CC=C3",3.125,1,3,6]
["S6455","Clebopride malate","g8","L4000-13","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Clebopride is a dopamine antagonist drug and is used to treat functional gastrointestinal disorder such as nausea or vomiting.",507.96,"57645-91-7",{"v":100,"d":"100.00"},196.87,{"v":33,"d":"33.00"},64.97,"http://www.selleck.cn/products/clebopride.html","C24H30ClN3O7","malate","N/A","COC1=C(C=C(Cl)C(=C1)N)C(=O)NC2CC[NH+](CC2)CC3=CC=CC=C3.OC(CC(O)=O)C([O-])=O",-1.413,3,3,8]
["S6457","Flurbiprofen Axetil","h8","L4000-13","in 10mM DMSO","COX","Immunology & Inflammation","Flurbiprofen Axetil is one of the commonly used nonsteroidal anti-inflammatory drugs (NSAIDs) that nonselectively inhibits cyclooxygenase.",330.35,"91503-79-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleck.cn/products/flurbiprofen-axetil.html","C19H19FO4","Free Base","N/A","CC(OC(C)=O)OC(=O)C(C)C1=CC=C(C(=C1)F)C2=CC=CC=C2",3.906,4,0,7]
["S6462","Amezinium (methylsulfate)","a9","L4000-13","in 10mM DMSO","MAO","Neuronal Signaling","Amezinium is a sympathomimetic used for its vasopressor effects in the treatment of hypotensive states. It is a MAO inhibitor, antagonizes the response to tyramine and blocks neuronal uptake of noradrenaline.",313.33,"30578-37-1",{"v":63,"d":"63.00"},201.07,{"v":32,"d":"32.00"},102.13,"http://www.selleck.cn/products/amezinium.html","C12H15N3O5S","methylsulfate","N/A","COC1=[N+](N=CC(=C1)N)C2=CC=CC=C2.CO[S]([O-])(=O)=O",{"v":-1.09,"d":"-1.090"},3,1,3]
["S6469","Thonzylamine","b9","L4000-13","in 10mM DMSO","AChR,Histamine Receptor","Neuronal Signaling","Thonzylamine (Neohetramine) is an antihistamine and anticholinergic drug.",286.37,"91-85-0",{"v":57,"d":"57.00"},199.04,{"v":57,"d":"57.00"},199.04,"http://www.selleck.cn/products/thonzylamine.html","C16H22N4O","Free Base","Neohetramine","COC1=CC=C(CN(CCN(C)C)C2=NC=CC=N2)C=C1",{"v":2.44,"d":"2.440"},3,0,7]
["S6470","Fluralaner","c9","L4000-13","in 10mM DMSO","Chloride Channel,GABA Receptor","Neuronal Signaling","Fluralaner (A1443, AH252723) is a systemic insecticide and acaricide that is administered orally.Fluralaner inhibits γ-aminobutyric acid (GABA)-gated chloride channels (GABAA receptors) and L-glutamate-gated chloride channels (GluCls)",556.29,"864731-61-3",{"v":100,"d":"100.00"},179.76,"<1","N/A","http://www.selleck.cn/products/fluralaner.html","C22H17Cl2F6N3O3","Free Base","A1443, AH252723","CC1=CC(=CC=C1C(=O)NCC(=O)NCC(F)(F)F)C2=NOC(C2)(C3=CC(=CC(=C3)Cl)Cl)C(F)(F)F",5.176,4,2,8]
["S6473","Pinaverium bromide","d9","L4000-13","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Pinaverium bromide (Icosapentaenoic acid) acts as a calcium channel blocker and is useful for functional gastrointestinal disorders.",591.42,"53251-94-8",{"v":100,"d":"100.00"},169.08,{"v":16,"d":"16.00"},27.05,"http://www.selleck.cn/products/pinaverium-bromide.html","C26H41Br2NO4","bromide","Icosapentaenoic acid","[Br-].COC1=C(OC)C=C(C[N+]2(CCOCCC3CCC4CC3C4(C)C)CCOCC2)C(=C1)Br",1.114,4,0,10]
["S6478","Fipexide hydrochloride","e9","L4000-13","in 10mM DMSO","cAMP","GPCR & G Protein","Fipexide (hydrochloride) is a psychoactive drug of the piperazine class.",425.31,"34161-23-4",{"v":85,"d":"85.00"},199.85,"<1","N/A","http://www.selleck.cn/products/fipexide-hydrochloride.html","C20H22Cl2N2O4","hydrochloride","N/A","Cl.ClC1=CC=C(OCC(=O)N2CCN(CC2)CC3=CC=C4OCOC4=C3)C=C1",3.434,4,0,5]
["S6479","Isohomovanillic acid","f9","L4000-13","in 10mM DMSO","Others","Others","Isohomovanillic acid is a deaminated metabolite of catecholamines formed by the enzyme catechol-O-methyltransferase which catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine.",182.17,"1131-94-8",{"v":36,"d":"36.00"},197.62,{"v":9,"d":"9.00"},{"v":49.4,"d":"49.40"},"http://www.selleck.cn/products/isohomovanillic-acid.html","C9H10O4","Free Base","N/A","COC1=CC=C(CC(O)=O)C=C1O",1.236,2,1,3]
["S6487","fluticasone furoate","g9","L4000-13","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Fluticasone furoate (GW685698) is an inhaled corticosteroid/long-acting beta-agonist combination with a prolonged bronchodilator duration of action. It is used for the treatment of non-allergic and allergic rhinitis administered by a nasal spray.",538.58,"397864-44-7",{"v":100,"d":"100.00"},185.67,"<1","N/A","http://www.selleck.cn/products/fluticasone-furoate.html","C27H29F3O6S","free base","GW685698","CC1CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(OC(=O)C5=CC=CO5)C(=O)SCF",4.479,5,1,6]
["S6503","LX2343","h9","L4000-13","in 10mM DMSO","BACE","Neuronal Signaling","LX2343 is a multi-target agent that exhibits a high capability for ameliorating multi-abnormalities of AD pathogenesis. It is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM.",474.91,"333745-53-2",{"v":95,"d":"95.00"},200.04,"<1","N/A","http://www.selleck.cn/products/lx2343.html","C22H19ClN2O6S","free base","N/A","COC1=CC=C(Cl)C=C1N(CC(=O)NC2=CC=C3OCOC3=C2)[S](=O)(=O)C4=CC=CC=C4",3.576,6,1,7]
["S6507","KN-92 phosphate","a10","L4000-13","in 10mM DMSO","CaMK","Neuronal Signaling","KN-92 is an inactive derivative of KN-93, the selective inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII).",554.98,"1135280-28-2",{"v":100,"d":"100.00"},180.19,"<1","N/A","http://www.selleck.cn/products/kn-92-phosphate.html","C24H28ClN2O7PS","phosphate","N/A","COC1=CC=C(C=C1)[S](=O)(=O)NC2=CC=CC=C2CN(C)C\\C=C\\C3=CC=C(Cl)C=C3.O[P](O)(O)=O",4.622,3,1,9]
["S6561","4-IBP","b10","L4000-13","in 10mM DMSO","Sigma Receptor","GPCR & G Protein","4-IBP is a selective σ1 receptor agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM).",420.29,"155798-08-6",{"v":84,"d":"84.00"},199.86,"<1","N/A","http://www.selleck.cn/products/4-ibp.html","C19H21IN2O","free base","N/A","IC1=CC=C(C=C1)C(=O)NC2CCN(CC2)CC3=CC=CC=C3",{"v":3.31,"d":"3.310"},1,1,4]
["S6569","VUF10460","c10","L4000-13","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","VUF10460 is a histamine H4 receptor agonist.",269.34,"1028327-66-3",{"v":54,"d":"54.00"},200.49,"<1","N/A","http://www.selleck.cn/products/vuf10460.html","C15H19N5","free base","N/A","CN1CCN(CC1)C2=NC(=NC(=C2)C3=CC=CC=C3)N",2.431,2,1,2]
["S6590","Hydrocortisone butyrate","d10","L4000-13","in 10mM DMSO","Others","Others","Hydrocortisone butyrate is a potent topical corticosteroid that can be used to treat a range of inflammatory skin conditions.",432.55,"13609-67-1",{"v":87,"d":"87.00"},201.13,"<1","N/A","http://www.selleck.cn/products/hydrocortisone-butyrate.html","C25H36O6","free base","N/A","CCCC(=O)OC1(CCC2C3CCC4=CC(=O)CCC4(C)C3C(O)CC12C)C(=O)CO",2.785,4,2,6]
["S6609","JZL195","e10","L4000-13","in 10mM DMSO","FAAH,Lipase","Metabolism","JZL195 is a potent inhibitor of both FAAH and MAGL with IC50s of 2 and 4 nM respectively.",433.46,"1210004-12-8",{"v":43,"d":"43.00"},{"v":99.2,"d":"99.20"},"<1","N/A","http://www.selleck.cn/products/jzl195.html","C24H23N3O5","free base","N/A","[O-][N+](=O)C1=CC=C(OC(=O)N2CCN(CC2)CC3=CC=CC(=C3)OC4=CC=CC=C4)C=C1",4.794,3,0,7]
["S6611","Cyclothiazide","f10","L4000-13","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Cyclothiazide is a positive allosteric modulator of ionotropic α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-type glutamate receptors with critical roles in neurological development and function.",389.88,"2259-96-3",{"v":78,"d":"78.00"},200.06,"<1","N/A","http://www.selleck.cn/products/cyclothiazide.html","C14H16ClN3O4S2","free base","N/A","N[S](=O)(=O)C1=CC2=C(NC(N[S]2(=O)=O)C3CC4CC3C=C4)C=C1Cl",1.228,4,3,2]
["S6612","Betazole Dihydrochloride","g10","L4000-13","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Betazole Dihydrochloride (Ametazole, 2-(3-Pyrazolyl)ethanamine) is a histamine H2 agonist used clinically to test gastric secretory function.",184.07,"138-92-1",{"v":37,"d":"37.00"},201.01,{"v":37,"d":"37.00"},201.01,"http://www.selleck.cn/products/betazole-dihydrochloride.html","C5H11Cl2N3","Dihydrochloride","Ametazole Dihydrochloride, 2-(3-Pyrazolyl)ethanamine Dihydrochloride","Cl.Cl.NCCC1=N[NH]C=C1",0.607,1,2,2]
["S7071","(+)-Bicuculline","h10","L4000-13","in 10mM DMSO","ADC Cytotoxin,GABA Receptor","Neuronal Signaling","(+)-Bicuculline (d-Bicuculline) is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels.",367.35,"485-49-4",{"v":21,"d":"21.00"},57.17,"<1","N/A","http://selleckchem.com/products/bicuculline.html","C20H17NO6","free base","d-Bicuculline","CN1CCC2=CC3=C(OCO3)C=C2C1C4OC(=O)C5=C6OCOC6=CC=C45",2.829,6,0,1]
["S7072","NMDA (N-Methyl-D-aspartic acid)","a11","L4000-13","in 10mM DMSO","NMDAR","Neuronal Signaling","NMDA（N-Methyl-D-aspartic acid）is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Phase 4.",147.13,"6384-92-5",{"v":5,"d":"5.00"},33.98,{"v":30,"d":"30.00"},{"v":203.9,"d":"203.90"},"http://selleckchem.com/products/nmda-n-methyl-d-aspartic-acid.html","C5H9NO4","free base","N/A","CNC(CC(O)=O)C(O)=O",-3.574,2,1,4]
["S7076","T0901317","b11","L4000-13","in 10mM DMSO","Apoptosis related,FXR,Liver X Receptor,ROR","Metabolism","T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of 20nM for LXRα and 5 μM for FXR, respectively. T0901317 is a dual inverse agonist of RORα and RORγ with Ki of 132 nM and 51 nM, respectively. T0901317 significantly suppresses cell proliferation and induces apoptosis.",481.33,"293754-55-9",{"v":96,"d":"96.00"},199.45,"<1","N/A","http://selleckchem.com/products/t0901317.html","C17H12F9NO3S","free base","N/A","OC(C1=CC=C(C=C1)N(CC(F)(F)F)[S](=O)(=O)C2=CC=CC=C2)(C(F)(F)F)C(F)(F)F",4.826,2,0,8]
["S7098","PD123319","c11","L4000-13","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM.",508.61,"130663-39-7",{"v":100,"d":"100.00"},196.61,{"v":100,"d":"100.00"},196.61,"http://selleckchem.com/products/pd123319.html","C31H32N4O3","free base","N/A","CN(C)C1=C(C)C=C(C[N]2C=NC3=C2CC(N(C3)C(=O)C(C4=CC=CC=C4)C5=CC=CC=C5)C(O)=O)C=C1",4.593,3,0,7]
["S7115","AMG-517","d11","L4000-13","in 10mM DMSO","TRP Channel","Transmembrane Transporters","AMG 517 is a potent and selective TRPV1 antagonist, and antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM， respectively.",{"v":430.4,"d":"430.40"},"659730-32-2",{"v":86,"d":"86.00"},199.81,"<1","N/A","http://selleckchem.com/products/amg-517.html","C20H13F3N4O2S","free base","N/A","CC(=O)NC1=NC2=C(S1)C=CC=C2OC3=CC(=NC=N3)C4=CC=C(C=C4)C(F)(F)F",4.785,5,1,5]
["S7124","SC144","e11","L4000-13","in 10mM DMSO","P-gp","Transmembrane Transporters","SC144 is the first-in-class orally active small-molecule gp130 inhibitor that induces gp130 phosphorylation (S782) and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the expression of downstream target genes.",{"v":322.3,"d":"322.30"},"895158-95-9",{"v":28,"d":"28.00"},86.88,"<1","N/A","http://selleckchem.com/products/sc144.html","C16H11FN6O","free base","N/A","FC1=CC2=C(C=C1)[N]3C=CC=C3C(=N2)NNC(=O)C4=CN=CC=N4",1.819,4,2,3]
["S7145","AZD1080","f11","L4000-13","in 10mM DMSO","GSK-3","PI3K/Akt/mTOR","AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor, inhibits human GSK3α and GSK3β with Ki of 6.9 nM and 31 nM, respectively, shows >14-fold selectivity against CDK2, CDK5, CDK1 and Erk2.",334.37,"612487-72-6",{"v":52,"d":"52.00"},155.52,"<1","N/A","http://selleckchem.com/products/azd1080.html","C19H18N4O2","free base","N/A","OC1=C(C2=CC=C(CN3CCOCC3)C=N2)C4=CC(=CC=C4[NH]1)C#N",2.442,2,2,3]
["S7152","C646","g11","L4000-13","in 10mM DMSO","Apoptosis related,Autophagy,Epigenetic Reader Domain,Histone Acetyltransferase","Epigenetics","C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM in a cell-free assay. Preferentially selective for p300 versus other acetyltransferases. C646 induces cell cycle arrest, apoptosis and autophagy.",445.42,"328968-36-1",{"v":13,"d":"13.00"},29.19,"<1","N/A","http://selleckchem.com/products/c646.html","C24H19N3O6","free base","N/A","CC1=C(C)C=C(C(=C1)C2=CC=C(O2)\\C=C/3C(=NN(C3=O)C4=CC=C(C=C4)C(O)=O)C)[N+]([O-])=O",4.736,4,0,5]
["S7162","Mdivi-1","h11","L4000-13","in 10mM DMSO","Apoptosis related,Dynamin,Mitophagy","Cytoskeletal Signaling","Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. Mdivi-1 attenuates mitophagy and enhances apoptosis.",353.22,"338967-87-6",{"v":70,"d":"70.00"},198.18,"<1","N/A","http://selleckchem.com/products/mdivi-1.html","C15H10Cl2N2O2S","free base","Mitochondrial division inhibitor 1","COC1=C(Cl)C=C(Cl)C(=C1)N2C(=NC3=C(C=CC=C3)C2=O)S",4.943,3,0,2]
["S7169","Crenigacestat (LY3039478)","a2","L4000-14","in 10mM DMSO","Gamma-secretase,Notch","Stem Cells & Wnt","Crenigacestat (LY3039478) is an oral Notch and gamma-secretase inhibitor with IC50 of 0.41 nM for Notch.",464.44,"1421438-81-4",{"v":92,"d":"92.00"},198.09,"<1","N/A","http://selleckchem.com/products/ly3039478.html","C22H23F3N4O4","free base","N/A","CC(NC(=O)CCC(F)(F)F)C(=O)NC1C(=O)N(CCO)C2=C(C=CC=N2)C3=C1C=CC=C3",1.395,4,3,8]
["S7188","CID755673","b2","L4000-14","in 10mM DMSO","CaMK,PKD","Apoptosis","CID755673 is a cell-active pan-PKD1/2/3 inhibitor with IC50 of 180 nM, 280nM, and 227 nM, respectively, about 200-fold selectivity over other CAMKs.",217.22,"521937-07-5",{"v":43,"d":"43.00"},196.13,"<1","N/A","http://selleckchem.com/products/cid755673.html","C12H11NO3","free base","N/A","OC1=CC2=C(OC3=C2CCCNC3=O)C=C1",1.922,2,2,0]
["S7193","1-Azakenpaullone","c2","L4000-14","in 10mM DMSO","GSK-3","PI3K/Akt/mTOR","1-Azakenpaullone (1-Akp) is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25.",328.16,"676596-65-9",{"v":66,"d":"66.00"},201.12,"<1","N/A","http://selleckchem.com/products/1-azakenpaullone.html","C15H10BrN3O","free base","1-Akp","BrC1=CC2=C([NH]C3=C2CC(=O)NC4=C3N=CC=C4)C=C1",2.949,2,2,0]
["S7237","OG-L002","d2","L4000-14","in 10mM DMSO","Histone Demethylase,LSD1","Epigenetics","OG-L002 is a potent and specific LSD1 inhibitor with IC50 of 20 nM in a cell-free assay, exhibiting 36- and 69-fold selectivity over MAO-B and MAO-A, respectively.",225.29,"1357302-64-7",{"v":45,"d":"45.00"},199.74,"<1","N/A","http://selleckchem.com/products/og-l002.html","C15H15NO","free base","N/A","NC1CC1C2=CC=C(C=C2)C3=CC=CC(=C3)O",{"v":2.47,"d":"2.470"},0,2,2]
["S7253","AZD2858","e2","L4000-14","in 10mM DMSO","GSK-3","PI3K/Akt/mTOR","AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, activating Wnt signaling, increases bone mass in rats.",453.52,"486424-20-8",{"v":7,"d":"7.00"},15.43,"<1","N/A","http://selleckchem.com/products/azd2858.html","C21H23N7O3S","free base","N/A","CN1CCN(CC1)[S](=O)(=O)C2=CC=C(C=C2)C3=CN=C(N)C(=N3)C(=O)NC4=CN=CC=C4",0.405,6,2,5]
["S7292","RG2833 (RGFP109)","f2","L4000-14","in 10mM DMSO","HDAC","Epigenetics","RG2833 (RGFP109) is a brain-penetrant HDAC inhibitor with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3 in cell-free assays, respectively.",339.43,"1215493-56-3",{"v":68,"d":"68.00"},200.34,"<1","N/A","http://selleckchem.com/products/rg2833-rgfp109.html","C20H25N3O2","free base","N/A","CC1=CC=C(C=C1)C(=O)NCCCCCC(=O)NC2=CC=CC=C2N",2.895,2,3,8]
["S7295","Apabetalone (RVX-208)","g2","L4000-14","in 10mM DMSO","Epigenetic Reader Domain","Epigenetics","Apabetalone (RVX-208, RVX-000222) is a potent BET bromodomain inhibitor with IC50 of 0.510 μM for BD2 in a cell-free assay, about 170-fold selectivity over BD1. Phase 2.",{"v":370.4,"d":"370.40"},"1044870-39-4",{"v":74,"d":"74.00"},199.78,"<1","N/A","http://selleckchem.com/products/rvx-208.html","C20H22N2O5","free base","RVX-000222","COC1=CC(=C2C(=O)NC(=NC2=C1)C3=CC(=C(OCCO)C(=C3)C)C)OC",2.877,5,2,6]
["S7323","Itanapraced (CHF 5074)","h2","L4000-14","in 10mM DMSO","Secretase,Secretase","Proteases","Itanapraced (CHF 5074, CSP-1103) is a gamma-secretase modulator that reduces Aβ42 and Aβ40 secretion. The IC50s of CHF5074 for inhibition of COX-1 and COX-2 is above 100 μmol/L.",325.16,"749269-83-8",{"v":65,"d":"65.00"},{"v":199.9,"d":"199.90"},"<1","N/A","http://www.selleckchem.com/products/chf-5074.html","C16H11Cl2FO2","Free Base","CSP-1103","OC(=O)C1(CC1)C2=CC(=C(C=C2)C3=CC=C(Cl)C(=C3)Cl)F",5.055,1,0,3]
["S7351","JSH-23","a3","L4000-14","in 10mM DMSO","NF-κB","NF-κB","JSH-23 is an inhibitor of NF-κB transcriptional activity with IC50 of 7.1 μM in RAW 264.7 cell line.",240.34,"749886-87-1",{"v":48,"d":"48.00"},199.72,"<1","N/A","http://selleckchem.com/products/jsh-23.html","C16H20N2","free base","N/A","CC1=CC=C(NCCCC2=CC=CC=C2)C(=C1)N",3.739,0,2,5]
["S7366","LY2119620","b3","L4000-14","in 10mM DMSO","AChR","Neuronal Signaling","LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.",437.94,"886047-22-9",{"v":87,"d":"87.00"},198.66,"<1","N/A","http://selleckchem.com/products/ly2119620.html","C19H24ClN5O3S","free base","N/A","CN1CCN(CC1)C(=O)COC2=C(Cl)C(=C3C(=C(SC3=N2)C(=O)NC4CC4)N)C",1.879,4,2,5]
["S7392","Loxistatin Acid (E-64C)","c3","L4000-14","in 10mM DMSO","COVID-19,Cysteine Protease","Proteases","Loxistatin Acid (E-64C, NSC 694279, EP 475), a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor. The cysteine protease cathepsin L is required for SARS-CoV-2 viral entry.",314.38,"76684-89-4",{"v":62,"d":"62.00"},197.21,{"v":2,"d":"2.00"},6.36,"http://selleckchem.com/products/loxistatin-acid-e-64c.html","C15H26N2O5","free base","NSC 694279, EP 475","CC(C)CCNC(=O)C(CC(C)C)NC(=O)C1OC1C(O)=O",1.037,4,2,9]
["S7393","Aloxistatin (E64d)","d3","L4000-14","in 10mM DMSO","COVID-19,Cysteine Protease","Proteases","Aloxistatin (E64d) is an irreversible and membrane-permeable cysteine protease inhibitor with blood platelet aggregation inhibiting activity. The cysteine protease cathepsin L is required for SARS-CoV-2 viral entry, and aloxistatin treatment reduced cellular entry of SARS-CoV-2 pseudovirions by 92.3%.",342.43,"88321-09-9",{"v":68,"d":"68.00"},198.58,"<1","N/A","http://selleckchem.com/products/Aloxistatin.html","C17H30N2O5","free base","E-64d","CCOC(=O)C1OC1C(=O)NC(CC(C)C)C(=O)NCCC(C)C",1.611,5,2,11]
["S7396","Calpeptin","e3","L4000-14","in 10mM DMSO","Apoptosis related,Cysteine Protease","Proteases","Calpeptin is a potent, cell-permeable calpain inhibitor with ID50 of 52 nM, 34 nM, 138 nM, and 40 nM for Calpain I (porcine erythrocytes), Calpain II (porcine kidney), Papainb, and Calpain I (human platelets), respectively. Calpeptin attenuates apoptosis and intracellular inflammatory changes in muscle cells.",362.46,"117591-20-5",{"v":72,"d":"72.00"},198.64,"<1","N/A","http://selleckchem.com/products/calpeptin.html","C20H30N2O4","free base","N/A","CCCCC(NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1)C=O",{"v":3.8,"d":"3.800"},4,2,12]
["S7399","FLI-06","f3","L4000-14","in 10mM DMSO","Notch","Stem Cells & Wnt","FLI-06 is a novel inhibitor of Notch signaling with EC50 of 2.3 μM.",438.52,"313967-18-9",{"v":88,"d":"88.00"},200.67,"<1","N/A","http://selleckchem.com/products/fli-06.html","C25H30N2O5","free base","N/A","CC1=C(C(C2=CC=C(C=C2)[N+]([O-])=O)C3=C(CC(C)(C)CC3=O)N1)C(=O)OC4CCCCC4",{"v":4.32,"d":"4.320"},3,1,5]
["S7420","CA-074 methyl ester (CA-074 Me)","g3","L4000-14","in 10mM DMSO","Cathepsin B,Cysteine Protease","Proteases","CA-074 methyl ester (CA-074 Me, Cathepsin B Inhibitor IV) is a membrane-permeable derivative of CA-074 and acts as an irreversible cathepsin B inhibitor.",397.47,"147859-80-1",{"v":79,"d":"79.00"},198.76,{"v":79,"d":"79.00"},198.76,"http://selleckchem.com/products/ca-074-methyl-ester.html","C19H31N3O6","free base","Cathepsin B Inhibitor IV","CCCNC(=O)C1OC1C(=O)NC(C(C)CC)C(=O)N2CCCC2C(=O)OC",0.484,6,2,10]
["S7422","KN-62","h3","L4000-14","in 10mM DMSO","CaMK","Neuronal Signaling","KN-62 is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.9 μM; also a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM). It is selective for CaMKII relative to PKA, PKC and MLCK, but inhibits CaMKI and CaMKIV equally well, The Ki value of KN-62 for CaMK V is 0.8 μM.",721.84,"127191-97-3",{"v":100,"d":"100.00"},138.53,"<1","N/A","http://selleckchem.com/products/kn-62.html","C38H35N5O6S2","free base","N/A","CN(C(CC1=CC=C(O[S](=O)(=O)C2=C3C=CN=CC3=CC=C2)C=C1)C(=O)N4CCN(CC4)C5=CC=CC=C5)[S](=O)(=O)C6=CC=CC7=C6C=CN=C7",4.532,6,0,10]
["S7423","KN-93 Phosphate","a4","L4000-14","in 10mM DMSO","Autophagy,CaMK","Neuronal Signaling","KN-93 Phosphate is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.37 μM, no remarkable inhibitory effects on APK, PKC, MLCK or Ca2+-PDE activities. KN-93 attenuates CaMKII-induced autophagy.",599.03,"1188890-41-6",{"v":100,"d":"100.00"},166.94,{"v":92,"d":"92.00"},153.58,"http://selleckchem.com/products/kn-93-phosphate.html","C26H29ClN2O4S.H3O4P","Phosphate","N/A","COC1=CC=C(C=C1)[S](=O)(=O)N(CCO)C2=CC=CC=C2CN(C)C\\C=C\\C3=CC=C(Cl)C=C3.O[P](O)(O)=O",4.288,3,1,11]
["S7435","AR-A014418","b4","L4000-14","in 10mM DMSO","GSK-3","PI3K/Akt/mTOR","AR-A014418 (GSK-3β Inhibitor VIII) is an ATP-competitive, and selective GSK3β inhibitor with IC50 and Ki of 104 nM and 38 nM in cell-free assays, without significant inhibition on 26 other kinases tested.",308.31,"487021-52-3",{"v":61,"d":"61.00"},197.85,"<1","N/A","http://selleckchem.com/products/A014418.html","C12H12N4O4S","free base","GSK-3β Inhibitor VIII","COC1=CC=C(CNC(=O)NC2=NC=C(S2)[N+]([O-])=O)C=C1",1.529,3,2,5]
["S7436","NH125","c4","L4000-14","in 10mM DMSO","CaMK","Neuronal Signaling","NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.",524.56,"278603-08-0",{"v":100,"d":"100.00"},190.64,"<1","N/A","http://selleckchem.com/products/nh125.html","C27H45IN2","iodide","N/A","[I-].CCCCCCCCCCCCCCCC[N+]1=C(C)[N](CC2=CC=CC=C2)C=C1",6.032,0,0,17]
["S7437","Sal003","d4","L4000-14","in 10mM DMSO","eIF,PERK,phosphatase","ER stress & UPR","Sal003 is a potent and cell-permeable eIF-2α phosphatase inhibitor.",463.21,"1164470-53-4",{"v":93,"d":"93.00"},200.77,"<1","N/A","http://selleckchem.com/products/sal003.html","C18H15Cl4N3OS","free base","N/A","ClC1=CC=C(NC(=S)NC(NC(=O)\\C=C\\C2=CC=CC=C2)C(Cl)(Cl)Cl)C=C1",6.298,1,3,8]
["S7445","APX-3330","e4","L4000-14","in 10mM DMSO","DNA/RNA Synthesis,NF-κB","DNA Damage/DNA Repair","APX-3330 (E3330) is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.",378.46,"136164-66-4",{"v":75,"d":"75.00"},198.17,"<1","N/A","http://selleckchem.com/products/e3330.html","C21H30O6","free base","E3330","CCCCCCCCCC(=C/C1=C(C)C(=O)C(=C(OC)C1=O)OC)\\C(O)=O",4.663,5,0,12]
["S7482","EHT 1864 2HCl","f4","L4000-14","in 10mM DMSO","Rho","Cell Cycle","EHT 1864 2HCl is a potent Rac family GTPase inhibitor with Kd of 40 nM, 50 nM, 60 nM and 250 nM for Rac1, Rac1b, Rac2 and Rac3, respectively.",581.47,"754240-09-0",{"v":100,"d":"100.00"},171.98,{"v":100,"d":"100.00"},171.98,"http://selleckchem.com/products/eht-1864.html","C25H29Cl2F3N2O4S","dihydrochloride","N/A","Cl.Cl.FC(F)(F)C1=CC2=C(C=C1)C(=CC=N2)SCCCCCOC3=COC(=CC3=O)CN4CCOCC4",4.663,5,0,11]
["S7519","GNF-5837","g4","L4000-14","in 10mM DMSO","Trk receptor","Protein Tyrosine Kinase","GNF-5837 is a selective, and orally bioavailable pan-TRK inhibitor for TrkA, and TrkB with IC50 of 8 nM, and 12 nM, respectively.",535.49,"1033769-28-6",{"v":100,"d":"100.00"},186.74,"<1","N/A","http://selleckchem.com/products/gnf-5837.html","C28H21F4N5O2","free base","N/A","CC1=CC=C(NC(=O)NC2=CC(=CC=C2F)C(F)(F)F)C=C1NC3=CC=C\\4C(=C3)NC(=O)C4=C\\C5=CC=C[NH]5",5.993,2,5,6]
["S7585","SB-334867","h4","L4000-14","in 10mM DMSO","OX Receptor","GPCR & G Protein","SB-334867 is a selective orexin-1 (OX1) receptor antagonist.",319.32,"792173-99-0",{"v":63,"d":"63.00"},197.29,"<1","N/A","http://selleckchem.com/products/sb-334867.html","C17H13N5O2","free base","N/A","CC1=NC2=C(O1)C=C(NC(=O)NC3=CC=NC4=CC=CN=C34)C=C2",1.773,5,2,2]
["S7588","Reversine","a5","L4000-14","in 10mM DMSO","Adenosine Receptor,Aurora Kinase","GPCR & G Protein","Reversine is a potent human A3 adenosine receptor antagonist with Ki of 0.66 μM, and a pan-aurora A/B/C kinase inhibitor with IC50 of 400 nM/500 nM/400 nM, respectively. Also used for stem cell dedifferentiation.",393.23,"656820-32-5",{"v":5,"d":"5.00"},12.72,"<1","N/A","http://selleckchem.com/products/reversine.html","C21H27N7O","free base","N/A","C1CCC(CC1)NC2=C3N=C[NH]C3=NC(=N2)NC4=CC=C(C=C4)N5CCOCC5",3.893,4,3,5]
["S7673","L-685,458","b5","L4000-14","in 10mM DMSO","Secretase","Proteases","L-685,458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.",672.85,"292632-98-5",{"v":100,"d":"100.00"},148.62,"<1","N/A","http://selleckchem.com/products/l-685-458.html","C39H52N4O6","free base","N/A","CC(C)CC(NC(=O)C(CC(O)C(CC1=CC=CC=C1)NC(=O)OC(C)(C)C)CC2=CC=CC=C2)C(=O)NC(CC3=CC=CC=C3)C(N)=O",{"v":5.62,"d":"5.620"},5,5,19]
["S7705","A-438079 HCl","c5","L4000-14","in 10mM DMSO","P2 Receptor","Neuronal Signaling","A-438079 HCl is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9.",342.61,"899431-18-6",{"v":61,"d":"61.00"},178.05,{"v":61,"d":"61.00"},178.05,"http://selleckchem.com/products/a-438079-hcl.html","C13H10Cl3N5","Hydrochloride","N/A","Cl.ClC1=CC=CC(=C1Cl)C2=NN=N[N]2CC3=CC=CN=C3",3.209,4,0,3]
["S7730","NU1025","d5","L4000-14","in 10mM DMSO","PARP","DNA Damage/DNA Repair","NU1025 (NSC 696807) is a potent PARP inhibitor with IC50 of 400 nM.",176.17,"90417-38-2",{"v":35,"d":"35.00"},198.67,"<1","N/A","http://selleckchem.com/products/nu1025.html","C9H8N2O2","free base","NSC 696807","CC1=NC2=C(C=CC=C2O)C(=O)N1",0.587,2,2,0]
["S7731","AZD3839","e5","L4000-14","in 10mM DMSO","BACE","Neuronal Signaling","AZD3839 is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.",431.41,"1227163-84-9",{"v":86,"d":"86.00"},199.35,"<1","N/A","http://selleckchem.com/products/azd3839.html","C24H16F3N5","free base","N/A","NC1=NC(C2=CC=CC(=C2)C3=CN=CN=C3)(C4=CC(=NC=C4)C(F)F)C5=CC=CC(=C15)F",3.574,4,1,4]
["S7745","ANA-12","f5","L4000-14","in 10mM DMSO","Trk receptor","Protein Tyrosine Kinase","ANA-12 is a selective TrkB antagonist with Kd of 10 nM and 12 μM for the high and low affinity sites, respectively.",407.49,"219766-25-3",{"v":37,"d":"37.00"},{"v":90.8,"d":"90.80"},"<1","N/A","http://selleckchem.com/products/ana-12.html","C22H21N3O3S","free base","N/A","O=C1NCCCCC1NC(=O)C2=CC=CC=C2NC(=O)C3=CC4=C(S3)C=CC=C4",3.088,3,3,4]
["S7762","TRx0237 (LMTX) mesylate","g5","L4000-14","in 10mM DMSO","Microtubule Associated","Cytoskeletal Signaling","TRx 0237 mesylate (LMTX, Hydromethylthionine) is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia.",477.62,"1236208-20-0",{"v":95,"d":"95.00"},{"v":198.9,"d":"198.90"},{"v":95,"d":"95.00"},{"v":198.9,"d":"198.90"},"http://selleckchem.com/products/trx0237-lmtx-mesylate.html","C16H19N3S.2CH4O3S","Dimesylate","Hydromethylthionine mesylate","C[NH+](C)C1=CC=C2NC3=C(SC2=C1)C=C(C=C3)[NH+](C)C.C[S]([O-])(=O)=O.C[S]([O-])(=O)=O",-4.637,0,1,2]
["S7772","Elacridar (GF120918)","h5","L4000-14","in 10mM DMSO","P-gp","Transmembrane Transporters","Elacridar (GF120918, GW120918, GG918, GW0918) is a potent P-gp (MDR-1) and BCRP inhibitor.",563.64,"143664-11-3",{"v":8,"d":"8.00"},14.19,"<1","N/A","http://selleckchem.com/products/elacridar-gf120918.html","C34H33N3O5","free base","GW120918, GG918, GW0918","COC1=C2NC3=C(C=CC=C3C(=O)NC4=CC=C(CCN5CCC6=C(C5)C=C(OC)C(=C6)OC)C=C4)C(=O)C2=CC=C1",5.742,5,2,8]
["S7782","Dasatinib Monohydrate","a6","L4000-14","in 10mM DMSO","Bcr-Abl,c-Kit,Src","Angiogenesis","Dasatinib Monohydrate (BMS-354825) is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.",506.02,"863127-77-9",{"v":21,"d":"21.00"},{"v":41.5,"d":"41.50"},"<1","N/A","http://selleckchem.com/products/dasatinib-monohydrate.html","C22H28ClN7O3S","Monohydrate","BMS-354825 Monohydrate","O.CC1=NC(=CC(=N1)NC2=NC=C(S2)C(=O)NC3=C(C)C=CC=C3Cl)N4CCN(CCO)CC4",3.232,4,3,7]
["S7818","Pexidartinib (PLX3397)","b6","L4000-14","in 10mM DMSO","Apoptosis related,c-Kit,CSF-1R,FLT3","Protein Tyrosine Kinase","Pexidartinib (PLX3397) is an oral, potent multi-targeted receptor tyrosine kinase inhibitor of CSF-1R, Kit (c-Kit), and FLT3 with IC50 of 20 nM, 10 nM and 160 nM, respectively. Pexidartinib (PLX3397) induces apoptosis and necrosis with antitumor activity. Phase 3.",417.81,"1029044-16-3",{"v":83,"d":"83.00"},198.65,"<1","N/A","http://selleckchem.com/products/pexidartinib-plx3397.html","C20H15ClF3N5","free base","N/A","FC(F)(F)C1=NC=C(CNC2=NC=C(CC3=C[NH]C4=NC=C(Cl)C=C34)C=C2)C=C1",4.811,3,2,6]
["S7858","Dibutyryl-cAMP (Bucladesine)","c6","L4000-14","in 10mM DMSO","PDE,PKA","GPCR & G Protein","Dibutyryl-cAMP (Bucladesine, dbcAMP) is a cell-permeable PKA activator by mimicing the action of endogenous cAMP. Dibutyryl-cAMP (Bucladesine) is also a phosphodiesterase (PDE) inhibitor.",491.37,"16980-89-5",{"v":98,"d":"98.00"},199.44,{"v":98,"d":"98.00"},199.44,"http://selleckchem.com/products/dibutyryl-camp-bucladesine.html","C18H23N5NaO8P","sodium salt","dbcAMP","CCCC(=O)NC1=NC=NC2=C1N=C[N]2C3OC4CO[P](=O)(O[Na])OC4C3OC(=O)CCC",1.028,10,1,9]
["S7889","Xanthohumol","d6","L4000-14","in 10mM DMSO","Acyltransferase,Apoptosis related,CMV,COX","Metabolism","Xanthohumol, a prenylated chalcone from hop, inhibits COX-1 and COX-2 activity and shows chemopreventive effects. Xanthohumol inhibits diacylglycerol acyltransferase 1 (DGAT1) and DGAT2 with both IC50 of 40 μM. Xanthohumol is also a potent antiviral agent against a series of DNA and RNA viruses. Xanthohumol induces growth inhibition and apoptosis in cancer cells. Phase 1.",{"v":354.4,"d":"354.40"},"6754-58-1",{"v":70,"d":"70.00"},197.52,"<1","N/A","http://selleckchem.com/products/xanthohumol.html","C21H22O5","free base","N/A","COC1=C(C(=C(CC=C(C)C)C(=C1)O)O)C(=O)\\C=C\\C2=CC=C(O)C=C2",4.816,2,3,6]
["S7914","Isoxazole 9 (ISX-9)","e6","L4000-14","in 10mM DMSO","TGF-beta/Smad,Wnt/beta-catenin","Stem Cells & Wnt","Isoxazole 9 (Isx-9) is a synthetic promotor of adult neurogenesis by triggering neuronal differentiation of adult neural stem/precursor cells (NSPCs). Isoxazole 9 (Isx-9) activates multiple pathways including TGF-β induced epithelial–mesenchymal transition (EMT) signaling, canonical and non-canonical Wnt signaling at different stages of cardiac differentiation.",234.27,"832115-62-5",{"v":46,"d":"46.00"},196.35,"<1","N/A","http://selleckchem.com/products/isoxazole-9-isx-9.html","C11H10N2O2S","free base","N/A","O=C(NC1CC1)C2=NOC(=C2)C3=CC=CS3",2.173,3,1,3]
["S7924","Bay K 8644","f6","L4000-14","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Bay K 8644 is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM.",{"v":356.3,"d":"356.30"},"71145-03-4",{"v":71,"d":"71.00"},199.27,"<1","N/A","http://selleckchem.com/products/bay-k-8644.html","C16H15F3N2O4","free base","N/A","COC(=O)C1=C(C)NC(=C(C1C2=C(C=CC=C2)C(F)(F)F)[N+]([O-])=O)C",2.673,2,1,5]
["S7960","Larotrectinib (LOXO-101) sulfate","g6","L4000-14","in 10mM DMSO","Apoptosis related,Trk receptor","Protein Tyrosine Kinase","Larotrectinib sulfate (LOXO-101, ARRY-470) is an oral potent and selective ATP-competitive inhibitor of tropomyosin receptor kinases (TRK). Larotrectinib inhibition of TRKs induces cellular apoptosis and G1 cell-cycle arrest.",526.51,"1223405-08-0",{"v":100,"d":"100.00"},189.93,"<1","N/A","http://selleckchem.com/products/loxo-101.html","C21H22F2N6O2.H2SO4","sulfate","ARRY-470, Larotrectinib","OC1CCN(C1)C(=O)NC2=C3N=C(C=C[N]3N=C2)N4CCCC4C5=CC(=CC=C5F)F.O[S](O)(=O)=O",1.374,3,2,3]
["S7968","P7C3","h6","L4000-14","in 10mM DMSO","NAMPT","Metabolism","P7C3 is a potent proneurogenic and neuroprotective chemical that targets NAMPT enzyme.",474.19,"301353-96-8",{"v":95,"d":"95.00"},200.34,"<1","N/A","http://selleckchem.com/products/p7c3.html","C21H18Br2N2O","free base","N/A","OC(CNC1=CC=CC=C1)C[N]2C3=C(C=C(Br)C=C3)C4=C2C=CC(=C4)Br",5.972,0,2,5]
["S7974","L755507","a7","L4000-14","in 10mM DMSO","Adrenergic Receptor,CRISPR/Cas9","GPCR & G Protein","L-755,507 is characterized as a potent and selective β3 adrenergic receptor partial agonist with EC50 of 0.43 nM. It is also recently identified to enhance CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs) and other cell types.",584.73,"159182-43-1",{"v":100,"d":"100.00"},171.02,"<1","N/A","http://selleckchem.com/products/l755507.html","C30H40N4O6S","free base","N/A","CCCCCCNC(=O)NC1=CC=C(C=C1)[S](=O)(=O)NC2=CC=C(CCNCC(O)COC3=CC=C(O)C=C3)C=C2",4.413,4,6,17]
["S7993","SKF38393 HCl","b7","L4000-14","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","SKF38393 HCl is a selective dopamine D1/D5 receptor agonist.",291.77,"62717-42-4",{"v":58,"d":"58.00"},198.79,"<1","N/A","http://selleckchem.com/products/skf38393-hcl.html","C16H17NO2.HCl","Hydrochloride","N/A","Cl.OC1=C(O)C=C2C(CNCCC2=C1)C3=CC=CC=C3",3.013,0,3,1]
["S7995","Ripasudil (K-115) hydrochloride dihydrate","c7","L4000-14","in 10mM DMSO","ROCK","Cell Cycle","Ripasudil (K-115) hydrochloride dihydrate is a potent ROCK inhibitor with IC50 of 51 nM and 19 nM for ROCK1 and ROCK2, respectively, used for the treatment of glaucoma and ocular hypertension.",395.88,"887375-67-9",{"v":26,"d":"26.00"},65.68,{"v":79,"d":"79.00"},199.56,"http://selleckchem.com/products/ripasudil-k-115.html","C15H18FN3O2S.ClH.2H2O","Hydrochloride dihydrate","N/A","O.O.Cl.CC1CNCCCN1[S](=O)(=O)C2=CC=CC3=CN=CC(=C23)F",0.739,3,1,2]
["S7998","Entrectinib (RXDX-101)","d7","L4000-14","in 10mM DMSO","ALK,Autophagy,ROS1,Trk receptor","Protein Tyrosine Kinase","Entrectinib (RXDX-101, NMS-E628) is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. Entrectinib (RXDX-101) induces autophagy. Phase 2.",560.64,"1108743-60-7",{"v":100,"d":"100.00"},178.37,"<1","N/A","http://selleckchem.com/products/entrectinib-rxdx-101.html","C31H34F2N6O2","free base","NMS-E628","CN1CCN(CC1)C2=CC=C(C(=O)NC3=N[NH]C4=C3C=C(CC5=CC(=CC(=C5)F)F)C=C4)C(=C2)NC6CCOCC6",4.952,3,3,7]
["S7999","SKF96365","e7","L4000-14","in 10mM DMSO","TRP Channel","Transmembrane Transporters","SKF96365, originally identified as a blocker of receptor-mediated calcium entry, is widely used diagnostically, as a blocker of transient receptor potential canonical type (TRPC) channels.",402.91,"130495-35-1",{"v":80,"d":"80.00"},198.56,{"v":80,"d":"80.00"},198.56,"http://selleckchem.com/products/skf96365.html","C22H26N2O3.HCl","hydrochloride","N/A","Cl.COC1=CC=C(CCCOC(C[N]2C=CN=C2)C3=CC=C(OC)C=C3)C=C1",4.114,4,0,10]
["S8001","Ricolinostat (ACY-1215)","f7","L4000-14","in 10mM DMSO","Apoptosis related,HDAC","Epigenetics","Ricolinostat (ACY-1215, Rocilinostat) is a selective HDAC6 inhibitor with IC50 of 5 nM in a cell-free assay. It is >10-fold more selective for HDAC6 than HDAC1/2/3 (class I HDACs) with slight activity against HDAC8, minimal activity against HDAC4/5/7/9/11, Sirtuin1, and Sirtuin2. Ricolinostat (ACY-1215) suppresses cell proliferation and promotes apoptosis. Phase 2.",{"v":433.5,"d":"433.50"},"1316214-52-4",{"v":86,"d":"86.00"},198.39,"<1","N/A","http://selleckchem.com/products/rocilinostat-acy-1215.html","C24H27N5O3","free base","Rocilinostat","ONC(=O)CCCCCCNC(=O)C1=CN=C(N=C1)N(C2=CC=CC=C2)C3=CC=CC=C3",3.917,4,2,11]
["S8010","PRX-08066 Maleic acid","g7","L4000-14","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","PRX-08066 Maleic acid is a selective 5-HT2B receptor antagonist with IC50 of 3.4 nM, prevents the severity of pulmonary arterial hypertension in the MCT rat model. Phase 2.",517.96,"866206-55-5",{"v":104,"d":"104.00"},200.79,{"v":104,"d":"104.00"},200.79,"http://selleckchem.com/products/prx-08066.html","C19H17ClFN5S.C4H4O4","Maleate","N/A","OC(=O)\\C=C/C(O)=O.FC1=CC=C(CN2CCC(CC2)NC3=NC=NC4=C3C=C(Cl)S4)C=C1C#N",0.701,4,1,6]
["S8018","Nirogacestat (PF-03084014)","h7","L4000-14","in 10mM DMSO","Apoptosis related,Secretase","Proteases","Nirogacestat (PF-03084014, PF-3084014) is a selective gamma-secretase inhibitor with IC50 of 6.2 nM in a cell-free assay. Nirogacestat (PF-03084014, PF-3084014) induces apoptosis. Phase 2.",489.64,"1290543-63-3",{"v":97,"d":"97.00"},{"v":198.1,"d":"198.10"},"<1","N/A","http://selleckchem.com/products/pf-03084014-pf-3084014.html","C27H41F2N5O","free base","PF-3084014","CCCC(NC1CCC2=CC(=CC(=C2C1)F)F)C(=O)NC3=C[N](C=N3)C(C)(C)CNCC(C)(C)C",5.042,2,3,11]
["S8020","GW0742","a8","L4000-14","in 10mM DMSO","PPAR","Metabolism","GW0742 is a potent and highly selective PPARβ/δ agonist, with IC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPARγ.",471.49,"317318-84-6",{"v":94,"d":"94.00"},199.37,"<1","N/A","http://selleckchem.com/products/gw0742.html","C21H17F4NO3S2","free base","N/A","CC1=CC(=CC=C1OCC(O)=O)SCC2=C(C)N=C(S2)C3=CC=C(C(=C3)F)C(F)(F)F",5.795,3,0,8]
["S8025","GSK3787","b8","L4000-14","in 10mM DMSO","PPAR","Metabolism","GSK3787 is a selective and irreversible antagonist of PPARδ with pIC50 of 6.6, with no measurable affinity for hPPARα or hPPARγ.",392.78,"188591-46-0",{"v":79,"d":"79.00"},201.13,"<1","N/A","http://selleckchem.com/products/gsk3787.html","C15H12ClF3N2O3S","free base","N/A","FC(F)(F)C1=CC=C(N=C1)[S](=O)(=O)CCNC(=O)C2=CC=C(Cl)C=C2",3.207,4,1,6]
["S8028","Tariquidar (XR9576)","c8","L4000-14","in 10mM DMSO","P-gp","Transmembrane Transporters","Tariquidar (XR9576) is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 5.1 nM in CHrB30 cell line, reverses drug resistance in MDR cell Lines. Phase 3.",646.73,"206873-63-4",{"v":52,"d":"52.00"},{"v":80.4,"d":"80.40"},"<1","N/A","http://selleckchem.com/products/tariquidar.html","C38H38N4O6","free base","XR9576","COC1=CC2=C(CN(CCC3=CC=C(NC(=O)C4=C(NC(=O)C5=CC6=CC=CC=C6N=C5)C=C(OC)C(=C4)OC)C=C3)CC2)C=C1OC",5.573,7,2,11]
["S8035","VU 0364439","d8","L4000-14","in 10mM DMSO","GluR","Neuronal Signaling","VU 0364439 is a mGlu4 positive allosteric modulator (PAM), with EC50 of 19.8 nM.",422.29,"1246086-78-1",{"v":85,"d":"85.00"},201.28,"<1","N/A","http://selleckchem.com/products/vu-0364439.html","C18H13Cl2N3O3S","Free Base","N/A","ClC1=C(N[S](=O)(=O)C2=C(Cl)C=C(NC(=O)C3=NC=CC=C3)C=C2)C=CC=C1",3.709,4,2,5]
["S8073","Optovin","e8","L4000-14","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Optovin is a reversible photoactivated TRPA1 activator.",315.41,"348575-88-2",{"v":63,"d":"63.00"},199.74,"<1","N/A","http://selleckchem.com/products/optovin.html","C15H13N3OS2","free base","N/A","CC1=CC(=C(C)[N]1C2=CC=CN=C2)\\C=C3\\SC(=S)NC3=O",2.858,2,1,2]
["S8097","C-DIM12","f8","L4000-14","in 10mM DMSO","Dopamine Receptor,Immunology & Inflammation related","Neuronal Signaling","C-DIM12 is a Nurr1 activator that stimulates Nurr1 mediated apoptosis axis in bladder cancer cells and tumors and inhibits NF-κB–dependent gene expression in glial cells.",356.85,"178946-89-9",{"v":71,"d":"71.00"},198.96,"<1","N/A","http://selleckchem.com/products/c-dim12.html","C23H17ClN2","free base","N/A","ClC1=CC=C(C=C1)C(C2=C[NH]C3=C2C=CC=C3)C4=C[NH]C5=C4C=CC=C5",6.339,0,2,3]
["S8104","SCH58261","g8","L4000-14","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","SCH 58261 is a potent and selective A2a adenosine receptor antagonist with Ki of 2.3 nM and 2 nM for rat A2a and bovine A2a, respectively.",345.36,"160098-96-4",{"v":69,"d":"69.00"},199.79,"<1","N/A","http://selleckchem.com/products/sch58261.html","C18H15N7O","free base","N/A","NC1=NC2=C(C=N[N]2CCC3=CC=CC=C3)C4=NC(=N[N]14)C5=CC=CO5",{"v":2.74,"d":"2.740"},5,1,4]
["S8105","ZM241385","h8","L4000-14","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","ZM-241385 is a high affinity antagonist ligand selective for the adenosine A2A receptor.",337.34,"139180-30-6",{"v":67,"d":"67.00"},198.61,"<1","N/A","http://selleckchem.com/products/zm241385.html","C16H15N7O2","free base","N/A","NC1=NC(=NC2=NC(=N[N]12)C3=CC=CO3)NCCC4=CC=C(O)C=C4",2.917,5,3,5]
["S8137","Capsazepine","a9","L4000-14","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Capsazepine acts as a competitive antagonist of capsaicin and a transient receptor potential vanilloid type 1(TRPV1) antagonist. If you want to do cell experiments, please select batch 01.",{"v":376.9,"d":"376.90"},"138977-28-3",{"v":75,"d":"75.00"},198.99,"<1","N/A","http://selleckchem.com/products/capsazepine.html","C19H21ClN2O2S","free base","N/A","OC1=CC2=C(CN(CCC2)C(=S)NCCC3=CC=C(Cl)C=C3)C=C1O",5.393,0,3,5]
["S8172","Ro 61-8048","b9","L4000-14","in 10mM DMSO","Hydroxylase","Metabolism","Ro 61-8048 is a high-affinity kynurenine 3-hydroxylase (KMO) inhibitor with IC50 and Ki of 37 nM and 4.8 nM, respectively.",421.45,"199666-03-0",{"v":84,"d":"84.00"},199.31,"<1","N/A","http://selleckchem.com/products/ro-61-8048.html","C17H15N3O6S2","free base","N/A","COC1=C(OC)C=C(C=C1)[S](=O)(=O)NC2=NC(=CS2)C3=CC=CC(=C3)[N+]([O-])=O",3.123,5,1,7]
["S8173","Verubecestat (MK-8931) Trifluoroacetate","c9","L4000-14","in 10mM DMSO","BACE","Neuronal Signaling","Verubecestat (MK-8931) Trifluoroacetate is a potent and selective beta-secretase inhibitor and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor.",523.43,"2095432-65-6",{"v":81,"d":"81.00"},154.75,"<1","N/A","http://selleckchem.com/products/verubecestat-mk-8931.html","C19H18F5N5O5S","Trifluoroacetat","MK-8931","CN1C(=N)NC(C)(C[S]1(=O)=O)C2=CC(=CC=C2F)NC(=O)C3=CC=C(F)C=N3.OC(=O)C(F)(F)F",2.198,5,2,4]
["S8180","PF-CBP1 HCl","d9","L4000-14","in 10mM DMSO","Epigenetic Reader Domain","Epigenetics","PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).It inhibits CREBBP and p300 bromodomains with IC50 of 125 and 363 nM respectively.",525.08,"2070014-93-4",{"v":100,"d":"100.00"},190.45,{"v":100,"d":"100.00"},190.45,"http://selleckchem.com/products/pf-cbp1.html","C29H36N4O3.HCl","Hydrochloride","N/A","Cl.CCCOC1=CC=C(CCC2=NC3=CC(=CC=C3[N]2CCN4CCOCC4)C5=C(C)ON=C5C)C=C1",5.432,5,0,10]
["S8183","Pimavanserin tartrate","e9","L4000-14","in 10mM DMSO","5-HT Receptor","GPCR & G Protein","Pimavanserin tartrate(ACP-103) is a potent and selective serotonin 5-HT2A inverse agonist with pIC50 of 8.73, used to treat psychosis associated with Parkinson’s disease.",{"v":1005.2,"d":"1005.20"},"706782-28-7",{"v":100,"d":"100.00"},99.48,{"v":100,"d":"100.00"},99.48,"http://selleckchem.com/products/pimavanserin.html","C50H68F2N6O4.C4H6O6","tartrate","ACP-103","CC(C)COC1=CC=C(CNC(=O)N(CC2=CC=C(F)C=C2)C3CCN(C)CC3)C=C1.CC(C)COC4=CC=C(CNC(=O)N(CC5=CC=C(F)C=C5)C6CCN(C)CC6)C=C4.OC(C(O)C(O)=O)C(O)=O",0.735,6,4,19]
["S8185","FPS-ZM1","f9","L4000-14","in 10mM DMSO","Beta Amyloid,Gamma-secretase","Neuronal Signaling","FPS-ZM1 is a blood-brain-barrier permeant, non-toxic, tertiary amide compound which is a high affinity RAGE-specific inhibitor, blocking Aβ binding to the V domain of RAGE.",327.85,"945714-67-0",{"v":65,"d":"65.00"},198.26,"<1",{"$error":"#VALUE!"},"http://selleckchem.com/products/fps-zm1.html","C20H22ClNO","free base","N/A","ClC1=CC=C(C=C1)C(=O)N(CC2=CC=CC=C2)C3CCCCC3",{"v":5.35,"d":"5.350"},1,0,4]
["S8192","SUN11602","g9","L4000-14","in 10mM DMSO","FGFR","Angiogenesis","SUN11602 is a small synthetic compound that mimics the neuroprotective activities of bFGF and activates key molecules in the FGF receptor-1-mitogen-activated protein kinase/extracellular signal-regulated kinase-1/2 kinase (FGFR-1-MEK/ERK) signaling pathway.",{"v":451.6,"d":"451.60"},"704869-38-5",{"v":90,"d":"90.00"},199.29,"<1","N/A","http://selleckchem.com/products/sun11602.html","C26H37N5O2","free base","N/A","CN(C1CCN(CC1)CC2=CC=C(C=C2)C(N)=O)C(=O)CNC3=C(C)C(=C(N)C(=C3C)C)C",2.799,2,3,7]
["S8193","Lanabecestat (AZD3293)","h9","L4000-14","in 10mM DMSO","BACE","Neuronal Signaling","Lanabecestat (AZD3293, LY3314814) is an oral beta-secretase 1 cleaving enzyme (BACE) inhibitor with an inhibitory constant Ki  of 0.4 nM.",412.53,"1383982-64-6",{"v":82,"d":"82.00"},198.77,"<1","N/A","http://selleckchem.com/products/azd3293-ly3314814.html","C26H28N4O","free base","LY3314814","COC1CCC2(CC1)CC3=C(C=C(C=C3)C4=CN=CC(=C4)C#CC)C25N=C(C)C(=N5)N",3.882,4,1,3]
["S8219","Bitopertin","a10","L4000-14","in 10mM DMSO","Amino acid transporter,GlyT","Neuronal Signaling","Bitopertin (RG1678,RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells.",543.46,"845614-11-1",{"v":100,"d":"100.00"},184.01,"<1","N/A","http://selleckchem.com/products/bitopertin-rg1678-ro-4917838.html","C21H20F7N3O4S","free base","RG1678, RO-4917838","CC(OC1=CC=C(C=C1C(=O)N2CCN(CC2)C3=NC=C(C=C3F)C(F)(F)F)[S](C)(=O)=O)C(F)(F)F",4.304,5,0,7]
["S8238","SB366791","b10","L4000-14","in 10mM DMSO","TRP Channel","Transmembrane Transporters","SB-366791 is a novel, potent, and selective, cinnamide TRPV1 antagonist with an IC50 of 5.7 nM.",287.74,"472981-92-3",{"v":57,"d":"57.00"},{"v":198.1,"d":"198.10"},"<1","N/A","http://selleckchem.com/products/sb366791.html","C16H14ClNO2","free base","N/A","COC1=CC=CC(=C1)NC(=O)/C=C/C2=CC=C(Cl)C=C2",{"v":3.73,"d":"3.730"},2,1,4]
["S8270","SRT2183","c10","L4000-14","in 10mM DMSO","Sirtuin","DNA Damage/DNA Repair","SRT2183 is a small-molecule activator of the sirtuin subtype SIRT1, currently being developed by Sirtris Pharmaceuticals.",468.57,"1001908-89-9",{"v":93,"d":"93.00"},198.48,"<1","N/A","http://selleckchem.com/products/srt2183.html","C27H24N4O2S","free base","N/A","OC1CCN(C1)CC2=CSC3=NC(=C[N]23)C4=C(NC(=O)C5=CC6=C(C=CC=C6)C=C5)C=CC=C4",{"v":3.6,"d":"3.600"},2,2,5]
["S8280","IMR-1","d10","L4000-14","in 10mM DMSO","Notch","Stem Cells & Wnt","IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 26 μM.",353.41,"310456-65-6",{"v":70,"d":"70.00"},198.07,"<1","N/A","http://selleckchem.com/products/imr-1.html","C15H15NO5S2","free base","N/A","CCOC(=O)COC1=CC=C(C=C1OC)\\C=C2/SC(=S)NC2=O",2.864,5,1,7]
["S8291","Atractylenolide I","e10","L4000-14","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Atractylenolide I is the major sesquiterpenoid of the rhizome of A. macrocephala and shows a wide spectrum of pharmacological activities such as antiinflammatory, digestion promoting, and antioxidant effects.",{"v":230.3,"d":"230.30"},"73069-13-3",{"v":46,"d":"46.00"},199.74,"<1","N/A","http://selleckchem.com/products/atractylenolide-i.html","C15H18O2","free base","N/A","CC1=C2CC3C(=C)CCCC3(C)C=C2OC1=O",3.323,2,0,0]
["S8301","Ossirene","f10","L4000-14","in 10mM DMSO","Immunology & Inflammation related,Interleukins","Immunology & Inflammation","AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.",312.05,"106566-58-9",{"v":62,"d":"62.00"},198.69,"<1","N/A","http://selleckchem.com/products/as101.html","C2H4Cl3O2Te.H4N","Coordination Co","AS101","[NH4+].Cl[Te-]1(Cl)(Cl)OCCO1",-0.379,2,0,0]
["S8314","5-Iodotubercidin","g10","L4000-14","in 10mM DMSO","Adenosine Kinase","Neuronal Signaling","5-Iodotubercidin (NSC 113939, 5-ITu) is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibits nucleoside transporter, CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC.",392.15,"24386-93-4",{"v":78,"d":"78.00"},{"v":198.9,"d":"198.90"},"<1","N/A","http://selleckchem.com/products/5-iodotubercidin.html","C11H13IN4O4","free base","NSC 113939, 5-ITu","NC1=NC=NC2=C1C(=C[N]2C3OC(CO)C(O)C3O)I",-0.525,3,4,2]
["S8319","7,8-Dihydroxyflavone","h10","L4000-14","in 10mM DMSO","Trk receptor","Protein Tyrosine Kinase","7,8-Dihydroxyflavone (7,8-DHF) acts as a potent and selective small-molecule agonist of the TrkB receptor (Kd ≈ 320 nM), the main signaling receptor of brain-derived neurotrophic factor (BDNF).",254.24,"38183-03-8",{"v":50,"d":"50.00"},196.66,"<1","N/A","http://selleckchem.com/products/7-8-dihydroxyflavone.html","C15H10O4","free base","7,8-DHF","OC1=CC=C2C(=O)C=C(OC2=C1O)C3=CC=CC=C3",2.652,2,2,1]
["S8348","BMS-935177","a11","L4000-14","in 10mM DMSO","BTK,Trk receptor","Angiogenesis","BMS-935177 is a potent, reversible Bruton's Tyrosine Kinase (BTK) inhibitor with an IC50 value of 2.8 nM and demonstrates good kinase selectivity. It is more potent against BTK than other kinase, including the other Tec family kinases (TEC, BMX, ITK, and TXK) over which the compound is between 5- and 67-fold selective.",502.56,"1231889-53-4",{"v":100,"d":"100.00"},198.98,"<1","N/A","http://selleckchem.com/products/bms-935177.html","C31H26N4O3","free base","N/A","CC1=C(C=CC=C1C2=CC=C(C(N)=O)C3=C2C4=C([NH]3)C=C(C=C4)C(C)(C)O)N5C=NC6=C(C=CC=C6)C5=O",5.011,3,2,4]
["S8367","GSK2193874","b11","L4000-14","in 10mM DMSO","TRP Channel","Transmembrane Transporters","GSK2193874 is an orally active, potent, and selective blocker of transient receptor potential vanilloid 4 (TRPV4) with IC50 values of 0.04 and 0.002 μM for hTRPV4 and rTRPV4, respectively.",691.62,"1336960-13-4",{"v":100,"d":"100.00"},144.59,"<1","N/A","http://selleckchem.com/products/gsk2193874.html","C37H38BrF3N4O","free base","N/A","FC(F)(F)C1=CC=CC(=C1)C2=NC3=CC(=CC=C3C(=C2CN4CCC(CC4)N5CCCCC5)C(=O)NC6(CC6)C7=CC=CC=C7)Br",7.893,2,1,8]
["S8380","YM-58483 (BTP2)","c11","L4000-14","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","YM-58483/BTP2 is a blocker of store-operated Ca2+ entry (SOCE), which regulates the activation of non-excitable cells such as lymphocytes.",421.32,"223499-30-7",{"v":84,"d":"84.00"},199.37,"<1","N/A","http://selleckchem.com/products/ym-58483-btp2.html","C15H9F6N5OS","free base","N/A","CC1=C(SN=N1)C(=O)NC2=CC=C(C=C2)[N]3N=C(C=C3C(F)(F)F)C(F)(F)F",4.564,4,1,5]
["S8407","PF-06273340","d11","L4000-14","in 10mM DMSO","Trk receptor","Protein Tyrosine Kinase","PF-06273340 is a highly potent, kinases elective, well-tolerated pan-Trk inhibitor with IC50 values of 6, 4, 3 nM for TrkA, TrkB, Trk C, respectively.",479.92,"1402438-74-7",{"v":95,"d":"95.00"},197.95,"<1","N/A","http://selleckchem.com/products/pf-06273340.html","C23H22ClN7O3","free base","N/A","CC(C)(CO)[N]1C=C(C(=O)C2=CN=CC(=C2)NC(=O)CC3=CC=C(Cl)C=N3)C4=CN=C(N)N=C14",1.582,6,3,7]
["S8409","KG-501 (2-naphthol-AS-E-phosphate)","e11","L4000-14","in 10mM DMSO","Epigenetic Reader Domain","Epigenetics","KG-501 (2-naphthol-AS-E-phosphate) is a cAMP response element-binding protein (CREB) inhibitor that disrupts CREB-dependent transcription (Ki = 10 μM) and CREB:CBP interaction (Ki = 50 μM). It also disrupts phospho (Ser-133) CREB binding to KIX with a Ki of ≈90 μM, using concentrations of CREB that were within the linear range of the binding assay.",377.72,"18228-17-6",{"v":20,"d":"20.00"},52.95,"<1","N/A","http://www.selleckchem.com/products/kg-501-2-naphthol-as-e-phosphate.html","C17H13ClNO5P","Free Base","N/A","O[P](O)(=O)OC1=CC2=CC=CC=C2C=C1C(=O)NC3=CC=C(Cl)C=C3",3.691,2,1,4]
["S8433","NS-398 (NS398)","f11","L4000-14","in 10mM DMSO","COX","Neuronal Signaling","NS-398 (N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide) is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC50 values for human recombinant COX-1 and -2 are 75 and 1.77 μM, respectively.",314.36,"123653-11-2",{"v":62,"d":"62.00"},197.23,"<1","N/A","http://selleckchem.com/products/ns-398-ns398.html","C13H18N2O5S","free base","N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide","C[S](=O)(=O)NC1=C(OC2CCCCC2)C=C(C=C1)[N+]([O-])=O",2.477,3,1,5]
["S8447","8-OH-DPAT (8-Hydroxy-DPAT)","g11","L4000-14","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","8-OH-DPAT (8-Hydroxy-DPAT) is a kind of classic 5-HT1A agonist with the pIC50 of 8.19. It has a selectivity of almost-1000 fold for a subtype of the 5-HT1 binding site; Its biological half-life is 1.5 hous.",247.38,"78950-78-4",{"v":49,"d":"49.00"},198.08,"<1","N/A","http://selleckchem.com/products/8-oh-dpat-8-hydroxy-dpat.html","C16H25NO","free base","N/A","CCCN(CCC)C1CCC2=CC=CC(=C2C1)O",4.287,0,1,5]
["S8459","TAK-063","h11","L4000-14","in 10mM DMSO","PDE","Metabolism","TAK-063 (Balipodect) is a novel and selective phosphodiesterase 10A(PDE10A) inhibitor with an IC50 of 0.30 nM.",428.42,"1238697-26-1",{"v":85,"d":"85.00"},{"v":198.4,"d":"198.40"},"<1","N/A","http://selleckchem.com/products/tak-063.html","C23H17FN6O2","free base","Balipodect","COC1=CN(N=C(C1=O)C2=CC=N[N]2C3=CC=CC=C3)C4=CC=C(C=C4F)[N]5C=CC=N5",3.983,5,0,5]
["S8511","Belizatinib (TSR-011)","a2","L4000-15","in 10mM DMSO","ALK,Trk receptor","Protein Tyrosine Kinase","\"Belizatinib (TSR-011) is a potent inhibitor of ALK (IC50=0.7 nM) and tropomyosin receptor kinase (TRK) (IC50 values less than 3 nM for TRK A, B, and C).\n\n\"",577.73,"1357920-84-3",{"v":100,"d":"100.00"},173.09,"<1","N/A","http://selleckchem.com/products/tsr-011-belizatinib.html","C33H44FN5O3","free base","N/A","CC(C)NC(=O)C1CCC(CC1)N2C(NC3=CC=C(CN4CCC(CC4)C(C)(C)O)C=C23)=NC(=O)C5=CC=C(F)C=C5",4.827,3,2,7]
["S8519","A-317491","b2","L4000-15","in 10mM DMSO","P2 Receptor","Neuronal Signaling","A-317491 is a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors with Ki values of 22 nM and 9 nM for human P2X3 and P2X2/3 receptors.",565.57,"475205-49-3",{"v":100,"d":"100.00"},176.81,"<1","N/A","http://selleckchem.com/products/a-317491.html","C33H27NO8","free base","N/A","OC(=O)C1=C(C=C(C(=O)N(CC2=CC(=CC=C2)OC3=CC=CC=C3)C4CCCC5=C4C=CC=C5)C(=C1)C(O)=O)C(O)=O",5.876,5,0,9]
["S8564","Verubecestat (MK-8931)","c2","L4000-15","in 10mM DMSO","BACE","Neuronal Signaling","Verubecestat (MK-8931) is a potent and selective beta-secretase (also known as Beta-site APP-cleaving enzyme 1) inhibitor.",409.41,"1286770-55-5",{"v":81,"d":"81.00"},197.85,"<1","N/A","http://selleckchem.com/products/verubecestat.html","C17H17F2N5O3S","free base","N/A","CN1C(=N)NC(C)(C[S]1(=O)=O)C2=CC(=CC=C2F)NC(=O)C3=CC=C(F)C=N3",1.314,4,2,3]
["S8573","Sitravatinib (MGCD516)","d2","L4000-15","in 10mM DMSO","Axl,c-Kit,Ephrin receptor,Trk receptor,VEGFR","Protein Tyrosine Kinase","Sitravatinib (MGCD516, MG-516) is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl.",629.68,"1123837-84-2",{"v":100,"d":"100.00"},158.81,"<1","N/A","http://selleckchem.com/products/sitravatinib-mgcd516.html","C33H29F2N5O4S","free base","MG-516","COCCNCC1=CC=C(N=C1)C2=CC3=C(S2)C(=CC=N3)OC4=CC=C(NC(=O)C5(CC5)C(=O)NC6=CC=C(F)C=C6)C=C4F",5.029,6,3,12]
["S8575","A2AR antagonist 1","e2","L4000-15","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","A2AR antagonist 1 is a potent A2AR (Adenosine A2A Receptor) antagonist with Ki values of 4 nM and 264 nM for A2AR and A1R, respectively.",{"v":309.3,"d":"309.30"},"443103-97-7",{"v":61,"d":"61.00"},197.22,"<1","N/A","http://selleckchem.com/products/a2ar-antagonist-1.html","C16H12FN5O","free base","N/A","NC1=NC2=C(C=N[N]2CC3=CC=CC=C3F)C(=N1)C4=CC=CO4",3.005,4,1,3]
["S8583","Repotrectinib (TPX-0005)","f2","L4000-15","in 10mM DMSO","ALK,ROS1,Src,Trk receptor","Protein Tyrosine Kinase","Repotrectinib (TPX-0005) is a novel ALK/ROS1/TRK inhibitor with the IC50 values of 1.01 nM for WT ALK, 1.26 nM for ALK(G1202R), and 1.08 nM for ALK(L1196M); also a potent SRC inhibitor (IC50 5.3 nM).",355.37,"1802220-02-5",{"v":70,"d":"70.00"},196.98,"<1","N/A","http://selleckchem.com/products/tpx-0005.html","C18H18FN5O2","free base","N/A","CC1CNC(=O)C2=C3N=C(NC(C)C4=C(O1)C=CC(=C4)F)C=C[N]3N=C2",2.005,4,2,0]
["S8598","S 38093","g2","L4000-15","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","S 38093 is a histamine H3 antagonist/inverse agonist with a moderate affinity for rat, mouse and human H3 receptors (Ki = 8.8, 1.44 and 1.2 μM, respectively) and no affinity for other histaminergic receptors.",288.38,"862896-30-8",{"v":57,"d":"57.00"},197.66,"<1","N/A","http://selleckchem.com/products/S-38093.html","C17H24N2O2","free base","N/A","NC(=O)C1=CC=C(OCCCN2CC3CCCC3C2)C=C1",2.201,2,1,6]
["S8603","NGP 555","h2","L4000-15","in 10mM DMSO","Secretase","Proteases","NGP 555 is a small-molecule modulator of  γ-secretase and has been successful in achieving good oral absorption, brain penetration, CNS activity, and specificity for a lipid-based membrane target preclinically.",406.52,"1304630-27-0",{"v":40,"d":"40.00"},{"v":98.4,"d":"98.40"},"<1","N/A","http://selleckchem.com/products/npg-555.html","C23H23FN4S","free base","N/A","CCC1=C(C)C=C(C)C(=C1)NC2=NC(=CS2)C3=CC=C([N]4C=NC(=C4)C)C(=C3)F",6.396,2,1,5]
["S8639","Diphenyleneiodonium chloride (DPI)","a3","L4000-15","in 10mM DMSO","NADPH-oxidase,NOS,ROS,TRP Channel","Immunology & Inflammation","Diphenyleneiodonium chloride (DPI) is an inhibitor of NADPH oxidase and also a potent, irreversible, and time-, temperature-dependent iNOS/eNOS inhibitor. Diphenyleneiodonium chloride (DPI) also functions as a TRPA1 activator and selectively inhibits intracellular reactive oxygen species (ROS).",314.55,"4673-26-1",{"v":13,"d":"13.00"},41.33,"<1","N/A","http://selleckchem.com/products/diphenyleneiodonium-chloride-dpi.html","C12H8I.Cl","chloride","N/A","[Cl-].[I+]1C2=CC=CC=C2C3=C1C=CC=C3",1.101,0,0,0]
["S8648","ACY-738","b3","L4000-15","in 10mM DMSO","HDAC","Epigenetics","ACY-738 inhibits HDAC6 with low nanomolar potency (IC50=1.7 nM) and a selectivity of 60- to 1500-fold over class I HDACs.",270.29,"1375465-91-0",{"v":54,"d":"54.00"},199.79,"<1","N/A","http://selleckchem.com/products/acy-738.html","C14H14N4O2","free base","N/A","ONC(=O)C1=CN=C(NC2(CC2)C3=CC=CC=C3)N=C1",1.325,3,2,4]
["S8689","Abequolixron (RGX-104)","c3","L4000-15","in 10mM DMSO","Liver X Receptor","Metabolism","Abequolixron (RGX-104) is a orally bioavailable liver X receptor agonist that modulates innate immunity via transcriptional activation of the ApoE gene.",632.54,"610318-03-1",{"v":100,"d":"100.00"},158.09,"<1","N/A","http://www.selleckchem.com/products/rgx-104.html","C34H34Cl2F3NO3","Free Base","N/A","Cl.CC(CCOC1=CC=CC(=C1)CC(O)=O)N(CC(C2=CC=CC=C2)C3=CC=CC=C3)CC4=CC=CC(=C4Cl)C(F)(F)F",{"v":5.85,"d":"5.850"},2,0,14]
["S8691","ML204","d3","L4000-15","in 10mM DMSO","TRP Channel","Transmembrane Transporters","ML204 is a novel, potent, and selective TRPC4 channel inhibitor with apparent IC50 values of about 1 μM in fluorescent intracellular Ca2+ assays and about 3 μM in whole-cell voltage clamp experiments. It exhibits some selectivity within the TRPC subfamily of channels and higher selectivity against other TRP channels and non-TRP channels.",226.32,"5465-86-1",{"v":45,"d":"45.00"},198.83,"N/A","N/A","http://selleckchem.com/products/ml204.html","C15H18N2","free base","N/A","CC1=CC(=NC2=CC=CC=C12)N3CCCCC3",4.121,1,0,1]
["S8694","CID16020046","e3","L4000-15","in 10mM DMSO","Cannabinoid Receptor","GPCR & G Protein","CID16020046 (C390-0219) is a selective GPR55 antagonist, inhibiting GPR55 constitutive activity with IC50 of 0.15 μM in yeast. It demonstrates weak activity against a broad spectrum of other GPCRs, ion channels, kinases, and nuclear receptor.",425.44,"834903-43-4",{"v":85,"d":"85.00"},199.79,"<1","N/A","https://www.selleckchem.com/products/cid16020046.html","C25H19N3O4","free base","C390-0219","CC1=CC=C(C=C1)C2=N[NH]C3=C2C(N(C3=O)C4=CC=C(C=C4)C(O)=O)C5=CC=CC(=C5)O",4.742,3,2,4]
["S8695","ML221","f3","L4000-15","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","ML221 is a potent apelin receptor (APJ) functional antagonist in cell-based assays that is >37-fold selective over the closely related angiotensin II type 1 (AT1) receptor. The IC50 values of ML221 are 0.70 and 1.75 μM in a cAMP assay and β-arrestin assay, respectively.",385.35,"877636-42-5",{"v":9,"d":"9.00"},23.36,"<1","N/A","http://selleckchem.com/products/ml221.html","C17H11N3O6S","salt","N/A","[O-][N+](=O)C1=CC=C(C=C1)C(=O)OC2=COC(=CC2=O)CSC3=NC=CC=N3",{"v":1.93,"d":"1.930"},6,0,7]
["S8725","A-804598","g3","L4000-15","in 10mM DMSO","P2 Receptor","Neuronal Signaling","A-804598 is a selective P2X7R antagonist with high affinity at rat (IC50 = 10 nM), mouse (IC50 = 9 nM) and human (IC50 = 11 nM) P2X7 receptors.",315.37,"1125758-85-1",{"v":63,"d":"63.00"},199.77,"<1","N/A","http://selleckchem.com/products/a-804598.html","C19H17N5","free base","N/A","CC(NC(NC#N)=NC1=C2C=CC=NC2=CC=C1)C3=CC=CC=C3",3.286,2,2,5]
["S8788","CH7057288","h3","L4000-15","in 10mM DMSO","Trk receptor","Protein Tyrosine Kinase","CH7057288 is a potent and selective TRK inhibitor with IC50 values of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB, and TRKC respectively.",569.67,"2095616-82-1",{"v":100,"d":"100.00"},175.54,"<1","N/A","http://www.selleck.cn/products/ch7057288.html","C32H31N3O5S","Free Base","N/A","CC1=CC(=CC(=N1)C#CC2=CC3=C(C=C2)C4=C(O3)C(C)(C)C5=CC(=CC=C5C4=O)N[S](C)(=O)=O)C(=O)NC(C)(C)C",5.151,6,2,6]
["S9022","20S-Ginsenoside Rg3","a4","L4000-15","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","20S-Ginsenoside Rg3 is extracted from traditional Chinese medicine, red ginseng. It exihits neuromodulatory, cognition enhancing, anti-inflammatory, antioxidative, anti-angiogenic, and anticancer activities.",785.01,"14197-60-5",{"v":10,"d":"10.00"},12.74,"N/A","N/A","https://www.selleckchem.com/products/20s-ginsenoside-rg3.html","C42H72O13","free base","3b-[2-O-b-D-Glucopyranosyl-b-D-glucopyranosyl)oxy]-dammar-24-ene-12b, 20 diol","CC(C)=CCCC(C)(O)C1CCC2(C)C1C(O)CC3C4(C)CCC(OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(C)(C)C4CCC23C",2.295,4,8,10]
["S9035","Isovitexin","b4","L4000-15","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Isovitexin (saponaretin, Apigenin-6-C-glucoside), an active component of many traditional Chinese medicines, has various activities, such as anti-oxidant, anti-inflammatory, anti-alzheimer disease (AD) effects and so on.",432.38,"29702-25-8",{"v":86,"d":"86.00"},{"v":198.9,"d":"198.90"},"N/A","N/A","https://www.selleckchem.com/products/isovitexin.html","C21H20O10","free base","saponaretin, Apigenin-6-C-glucoside","OCC1OC(C(O)C(O)C1O)C2=C(O)C3=C(OC(=CC3=O)C4=CC=C(O)C=C4)C=C2O",0.018,3,7,3]
["S9039","Albiflorin","c4","L4000-15","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Albiflorin, a natural product isolated from Paeoniae Radix, is a novel 5-HT and NE reuptake inhibitor with high selectivity.",480.46,"39011-90-0",{"v":10,"d":"10.00"},20.81,"N/A","N/A","https://www.selleckchem.com/products/albiflorin.html","C23H28O11","free base","OA10410","CC12CC(O)C3CC1(OC4OC(CO)C(O)C(O)C4O)C3(COC(=O)C5=CC=CC=C5)C(=O)O2",-1.333,6,5,7]
["S9040","Maslinic acid","d4","L4000-15","in 10mM DMSO","NF-κB","NF-κB","Maslinic Acid (Crategolic Acid, 2α-Hydroxyoleanoic Acid), a Natural Triterpene, exerts a wide range of biological activities, i.e. antitumor, antidiabetic, antioxidant, cardioprotective, neuroprotective, antiparasitic and growth-stimulating. MA significantly suppresses the DNA-binding activity of NF-κB p65 in LPS-induced RAW 264.7 cells.",{"v":472.7,"d":"472.70"},"4373-41-5",{"v":10,"d":"10.00"},21.16,"N/A","N/A","https://www.selleckchem.com/products/maslinic-acid.html","C30H48O4","free base","Crategolic Acid, 2α-Hydroxyoleanoic Acid","CC1(C)CCC2(CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(C)C5CCC34C)C2C1)C(O)=O",{"v":5.48,"d":"5.480"},1,2,1]
["S9047","Leonurine Hydrochloride","e4","L4000-15","in 10mM DMSO","Others","Others","Leonurine (SCM-198), a natural alkaloid extracted from Herba leonuri, is a promising anti-glycation agent with vasodilator, antioxidative, cardioprotective and neuroprotective effects.",347.79,"24735-18-0",{"v":70,"d":"70.00"},201.27,"N/A","N/A","https://www.selleckchem.com/products/leonurine-hydrochloride.html","C14H22ClN3O5","free base","SCM-198 HCl","Cl.COC1=C(O)C(=CC(=C1)C(=O)OCCCCNC(N)=N)OC",1.472,4,3,10]
["S9049","Parishin A","f4","L4000-15","in 10mM DMSO","Others","Neuronal Signaling","Parishin A, isolated from the rhizomes of Gastrodia elata, has good neuroprotective effects against brain disorders.",996.91,"62499-28-9",{"v":10,"d":"10.00"},10.03,"N/A","N/A","https://www.selleckchem.com/products/parishin-a.html","C45H56O25","free base","FP74230","OCC1OC(OC2=CC=C(COC(=O)CC(O)(CC(=O)OCC3=CC=C(OC4OC(CO)C(O)C(O)C4O)C=C3)C(=O)OCC5=CC=C(OC6OC(CO)C(O)C(O)C6O)C=C5)C=C2)C(O)C(O)C1O",-2.407,12,12,23]
["S9052","Auraptene","g4","L4000-15","in 10mM DMSO","Immunology & Inflammation related,Interleukins,MMP","Immunology & Inflammation","Auraptene (7-geranyloxycoumarin) is a natural coumarin derived from citrus plants and possesses valuable pharmacological properties, including anticarcinogenic, anti-inflammatory, antihelicobacter, antigenotoxic, and neuroprotective effects. Auraptene inhibits matrix metalloproteinase 2 (MMP-2) as well as key inflammatory mediators, including IL-6, IL-8 and chemokine (C-C motif) ligand-5(CCL5).",298.38,"495-02-3",{"v":10,"d":"10.00"},33.51,"N/A","N/A","https://www.selleckchem.com/products/auraptene.html","C19H22O3","free base","7-geranyloxycoumarin","CC(C)=CCC/C(C)=C/COC1=CC2=C(C=CC(=O)O2)C=C1",5.175,3,0,6]
["S9065","Songorine","h4","L4000-15","in 10mM DMSO","ADC Cytotoxin,GABA Receptor","Neuronal Signaling","Songorine, a ubiquitous alkaloid in the genus Aconitum, is a novel antagonist of the GABAA receptor in rat brain and has antiarrhythmic, antinociceptive, anti-inflammatory, regenerative and CNS-modulating properties.",357.49,"509-24-0",{"v":10,"d":"10.00"},27.97,"N/A","N/A","https://www.selleckchem.com/products/songorine.html","C22H31NO3","free base","FS145273","CCN1CC2(C)CCC(O)C34C1C(CC23)C56CC(C(=C)C5O)C(=O)CC46",1.035,1,2,1]
["S9069","Jatrorrhizine chloride","a5","L4000-15","in 10mM DMSO","AChR","Neuronal Signaling","Jatrorrhizine chloride (Neprotine, Yatrorhizine) is the hydrochloride salt form of jatrorrhizine, which is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.",373.83,"6681-15-8",{"v":10,"d":"10.00"},26.75,"N/A","N/A","https://www.selleckchem.com/products/jatrorrhizine-chloride.html","C20H20ClNO4","Chloride salt","Neprotine chloride, Yatrorhizine chloride","[Cl-].COC1=CC2=C(CC[N+]3=CC4=C(C=CC(=C4OC)OC)C=C23)C=C1O",1.262,3,1,3]
["S9080","Anhydroicaritin","b5","L4000-15","in 10mM DMSO","Others","Apoptosis","Anhydroicaritin (Cycloicaritin), a prenylated flavonoid natural product, is commonly recognized as one of the effective compounds of Epimedii Herba and exhibits a variety of biological activities, such as activation of cancer cell apoptosis and inhibition of growth, protection against beta amyloid-induced neurotoxicity, and promotion of neuronal and cardiac cellular differentiation. It is a potent inhibitor of transcription factor SREBPs.",368.38,"118525-40-9",{"v":10,"d":"10.00"},27.15,"N/A","N/A","https://www.selleckchem.com/products/anhydroicaritin.html","C21H20O6","free base","Cycloicaritin","COC1=CC=C(C=C1)C2=C(O)C(=O)C3=C(O)C=C(O)C(=C3O2)CC=C(C)C",3.954,3,3,4]
["S9085","Corynoline","c5","L4000-15","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Corynoline is one of the major active components of many ethnopharmacological plants and exhibits anti-tumor, anti-inflammatory and hepatoprotective activities, etc.",{"v":367.4,"d":"367.40"},"18797-79-0",{"v":10,"d":"10.00"},27.22,"N/A","N/A","https://www.selleckchem.com/products/corynoline.html","C21H21NO5","free base","N/A","CN1CC2=C(C=CC3=C2OCO3)C4(C)C(O)CC5=C(C=C6OCOC6=C5)C14",2.732,4,1,0]
["S9087","Tenuifolin","d5","L4000-15","in 10mM DMSO","AChR,Beta Amyloid","Neuronal Signaling","Tenuifolin, a secondary saponin isolated from hydrolysates of polygalasaponins, inhibits beta-amyloid synthesis in vitro and has nootropic activity in vivo via acetylcholine esterase inhibition and increases norepinephrine and dopamine production.",680.82,"20183-47-5",{"v":100,"d":"100.00"},146.88,"N/A","N/A","https://www.selleckchem.com/products/tenuifolin.html","C36H56O12","free base","N/A","CC1(C)CCC2(CCC3(CO)C(=CCC4C5(C)CC(O)C(OC6OC(CO)C(O)C(O)C6O)C(C)(C5CCC34C)C(O)=O)C2C1)C(O)=O",1.786,4,6,6]
["S9088","Calycosin-7-O-beta-D-glucoside","e5","L4000-15","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Calycosin-7-O-beta-D-glucoside, an isoflavone glycoside isolated from A. mongholicus and A. membranaceus, has antioxidant, anti-inflammatory, and neuroprotective biological activities.",{"v":446.4,"d":"446.40"},"20633-67-4",{"v":10,"d":"10.00"},{"v":22.4,"d":"22.40"},"N/A","N/A","https://www.selleckchem.com/products/calycosin-7-o-beta-d-glucoside.html","C22H22O10","free base","N/A","COC1=C(O)C=C(C=C1)C2=COC3=C(C=CC(=C3)OC4OC(CO)C(O)C(O)C4O)C2=O",0.436,5,5,5]
["S9092","Norisoboldine","f5","L4000-15","in 10mM DMSO","AhR","Metabolism","Norisoboldine (Laurelliptine), a natural aryl hydrocarbon receptor (AhR) agonist, attenuates ulcerative colitis (UC) and induces the generation of Treg cells.",313.35,"23599-69-1",{"v":62,"d":"62.00"},197.86,"N/A","N/A","https://www.selleckchem.com/products/norisoboldine.html","C18H19NO4","free base","Laurelliptine","COC1=CC2=C(CC3NCCC4=C3C2=C(O)C(=C4)OC)C=C1O",2.547,2,3,2]
["S9093","Nardosinone","g5","L4000-15","in 10mM DMSO","Others","Others","Nardosinone, isolated from Nardostachys root, an important Chinese herbal medicine, is an enhancer of nerve growth factor and possesses a wide range of pharmacological effects, including sedative, adaptogen-like, anti-depressive, anti-leukemic, anti-tumorous, and anti-trypanosomal activities.",250.33,"23720-80-1",{"v":50,"d":"50.00"},199.73,"N/A","N/A","https://www.selleckchem.com/products/nardosinone.html","C15H22O3","free base","N/A","CC1CCC=C2C(=O)CC3OOC(C)(C)C3C12C",{"v":2.18,"d":"2.180"},3,0,0]
["S9099","Orientin","h5","L4000-15","in 10mM DMSO","Antiviral,Bacterial,Immunology & Inflammation related","Immunology & Inflammation","Orientin (Lutexin, Luteolin-8-glucoside), isolated from medicinal plants, has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects.",448.38,"28608-75-5",{"v":89,"d":"89.00"},198.49,"N/A","N/A","https://www.selleckchem.com/products/orientin.html","C21H20O11","free base","Lutexin, Luteolin-8-glucoside","OCC1OC(C(O)C(O)C1O)C2=C(O)C=C(O)C3=C2OC(=CC3=O)C4=CC(=C(O)C=C4)O",-0.224,3,8,3]
["S9100","Fraxinellone","a6","L4000-15","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Fraxinellone is a natural product isolated from the D. dasycarpus plant, which has been shown to exhibit neuroprotective and anti-inflammatory activities.",232.27,"28808-62-0",{"v":46,"d":"46.00"},198.04,"N/A","N/A","https://www.selleckchem.com/products/fraxinellone.html","C14H16O3","free base","N/A","CC1=C2C(=O)OC(C3=COC=C3)C2(C)CCC1",2.995,3,0,1]
["S9107","Glycitein","b6","L4000-15","in 10mM DMSO","ROS","Immunology & Inflammation","Glycitein is an aglycone isoflavone found in soy and red clover and exhibits a wide variety of beneficial properties, including neuroprotective, antioxidative, anticancer, anti-osteoporotic, and anti-atherosclerotic activities.",284.26,"40957-83-3",{"v":10,"d":"10.00"},35.18,"N/A","N/A","https://www.selleckchem.com/products/glycitein.html","C16H12O5","free base","N/A","COC1=CC2=C(OC=C(C2=O)C3=CC=C(O)C=C3)C=C1O",2.366,3,2,2]
["S9108","Timosaponin A3","c6","L4000-15","in 10mM DMSO","Others","Others","Timosaponin A3 (Filiferin B, AneMarsaponin A3), one of the major steroidal saponin components isolated from Anemarrhena asphodeloides, displays promising pharmacological activity in improving learning, memory, and antineoplastic activity.",740.92,"41059-79-4",{"v":100,"d":"100.00"},134.97,"N/A","N/A","https://www.selleckchem.com/products/timosaponin-a3.html","C39H64O13","free base","Filiferin B, AneMarsaponin A3","CC1CCC2(OC1)OC3CC4C5CCC6CC(CCC6(C)C5CCC4(C)C3C2C)OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O",{"v":1.39,"d":"1.390"},6,7,6]
["S9112","Kaempferitrin","d6","L4000-15","in 10mM DMSO","Anti-infection,Immunology & Inflammation related","Immunology & Inflammation","Kaempferitrin (Lespenefril, Lespedin, Lespenephryl, Kaempferol 3,7-dirhamnoside), isolated from the leaves of Hedyotis verticillata and from Onychium japonicum, has antimicrobial, antioxidant, and anti-inflammatory activities.",578.52,"482-38-2",{"v":100,"d":"100.00"},172.86,"N/A","N/A","https://www.selleckchem.com/products/kaempferitrin.html","C27H30O14","free base","Lespenefril, Lespedin, Lespenephryl, Kaempferol 3,7-dirhamnoside","CC1OC(OC2=CC3=C(C(=C2)O)C(=O)C(=C(O3)C4=CC=C(O)C=C4)OC5OC(C)C(O)C(O)C5O)C(O)C(O)C1O",-0.211,6,8,5]
["S9115","Wogonoside","e6","L4000-15","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Wogonoside (Oroxindin, Wogonin 7-O-glucuronide, Glychionide B), the main flavonoid component derived from the root of Scutellaria baicalensis Georgi, displays anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic activities.",460.39,"51059-44-0",{"v":38,"d":"38.00"},82.54,"N/A","N/A","https://www.selleckchem.com/products/wogonoside.html","C22H20O11","free base","Oroxindin, Wogonin 7-O-glucuronide, Glychionide B","COC1=C(OC2OC(C(O)C(O)C2O)C(O)=O)C=C(O)C3=C1OC(=CC3=O)C4=CC=CC=C4",0.833,6,4,5]
["S9118","Beta-Asarone","f6","L4000-15","in 10mM DMSO","Others","Others","Beta-Asarone, found in certain plants such as Acorus and Asarum, could pass the blood-brain barrier and exerts neuroprotection effects.",208.25,"5273-86-9","N/A","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","https://www.selleckchem.com/products/beta-asarone.html","C12H16O3","free base","N/A","COC1=CC(=C(\\C=C/C)C=C1OC)OC",2.734,3,0,4]
["S9129","20(S)-Ginsenoside Rh1","g6","L4000-15","in 10mM DMSO","Immunology & Inflammation related,Interleukins,PPAR,TNF-alpha","Immunology & Inflammation","20(S)-Ginsenoside Rh1 (Prosapogenin A2, Sanchinoside B2, Sanchinoside Rh1) is one of major bioactive compounds extracted from red ginseng, which has been increasingly used for enhancing cognition and physical health worldwide. It exhibits potent characteristics of anti-inflammatory, antioxidant, immunomodulatory effects, and positive effects on the nervous system. Ginsenoside Rh1 inhibits the expression of PPAR-γ, TNF-α, IL-6, and IL-1β.",638.87,"63223-86-9",{"v":100,"d":"100.00"},156.53,"N/A","N/A","https://www.selleckchem.com/products/20-s-ginsenoside-rh1.html","C36H62O9","free base","Prosapogenin A2, Sanchinoside B2, Sanchinoside Rh1","CC(C)=CCCC(C)(O)C1CCC2(C)C1C(O)CC3C4(C)CCC(O)C(C)(C)C4C(CC23C)OC5OC(CO)C(O)C(O)C5O",2.873,2,6,7]
["S9134","Spinosin","h6","L4000-15","in 10mM DMSO","Others","Neuronal Signaling","Spinosin (Flavoayamenin), a ﬂavone-C-glycoside, is a bioactive ingredient isolated from a traditional Chinese herb Zizyphi Spinosi Semen. It acts as a plant metabolite and an anxiolytic drug.",608.54,"72063-39-9",{"v":100,"d":"100.00"},164.33,"N/A","N/A","https://www.selleckchem.com/products/spinosin.html","C28H32O15","free base","Flavoayamenin","COC1=CC2=C(C(=C1C3OC(CO)C(O)C(O)C3OC4OC(CO)C(O)C(O)C4O)O)C(=O)C=C(O2)C5=CC=C(O)C=C5",-1.503,6,9,7]
["S9136","Neochlorogenic acid","a7","L4000-15","in 10mM DMSO","Antiviral,Bacterial,Immunology & Inflammation related","Immunology & Inflammation","Neochlorogenic acid (Neochlorogenate, 5-O-Caffeoylquinic acid) is a natural polyphenolic compound found in some types of dried fruits and a variety of other plant sources such as peaches. It shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia.",354.31,"906-33-2",{"v":70,"d":"70.00"},197.57,"N/A","N/A","https://www.selleckchem.com/products/neochlorogenic-acid.html","C16H18O9","free base","Neochlorogenate, 5-O-Caffeoylquinic acid","OC1CC(O)(CC(OC(=O)\\C=C\\C2=CC=C(O)C(=C2)O)C1O)C(O)=O",{"v":-0.34,"d":"-0.340"},3,4,5]
["S9140","Pulegone","b7","L4000-15","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Pulegone, a naturally occurring organic compound, is a fragrance and flavour ingredient.pulegone stimulates both TRPM8 and TRPA1 channel in chicken sensory neurons and suppresses the former but not the latter at high concentrations.",152.23,"89-82-7","N/A","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","https://www.selleckchem.com/products/pulegone.html","C10H16O","free base","N/A","CC1CCC(=C(C)C)C(=O)C1",2.891,1,0,0]
["S9142","Sparteine","c7","L4000-15","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Sparteine, which could be extracted from scotch broom, is a sodium channel blocker and a class 1a antiarrhythmic agent.",234.38,"492-08-0","N/A","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","https://www.selleckchem.com/products/sparteine.html","C15H26N2","free base","N/A","C1CCN2CC3CC(CN4CCCCC34)C2C1",2.363,0,0,0]
["S9146","Anwuligan","d7","L4000-15","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Anwuligan (Macelignan), a natural compound isolated from Myristica fragrans Houtt, has antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species. It also shows antioxidant, free radical scavenging, and neuroprotective activities.",{"v":328.4,"d":"328.40"},"107534-93-0",{"v":65,"d":"65.00"},197.93,"N/A","N/A","https://www.selleckchem.com/products/anwuligan.html","C20H24O4","free base","Macelignan","COC1=C(O)C=CC(=C1)CC(C)C(C)CC2=CC3=C(OCO3)C=C2",5.186,3,1,6]
["S9149","Benzoylpaeoniflorin","e7","L4000-15","in 10mM DMSO","COX","Immunology & Inflammation","Benzoylpaeoniflorin, a natural product isolated from Chinese paeony root, could inhibit COX-1 and COX-2 in vitro.",584.57,"38642-49-8",{"v":100,"d":"100.00"},171.07,"N/A","N/A","https://www.selleckchem.com/products/benzoylpaeoniflorin.html","C30H32O12","free base","N/A","CC12CC3(O)OC(O1)C4(COC(=O)C5=CC=CC=C5)C3CC24OC6OC(COC(=O)C7=CC=CC=C7)C(O)C(O)C6O",{"v":0.76,"d":"0.760"},8,3,10]
["S9151","Praeruptorin E","f7","L4000-15","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Praeruptorin E, isolated from Peucedanum praeruptorum Dunn., is a cardiotonic agent with selective cardiac calcium channel agonistic effect.",428.47,"78478-28-1",{"v":34.6,"d":"34.60"},80.75,"N/A","N/A","https://www.selleckchem.com/products/praeruptorin-e.html","C24H28O7","free base","N/A","C\\C=C(C)/C(=O)OC1C(OC(=O)CC(C)C)C2=C3OC(=O)C=CC3=CC=C2OC1(C)C",4.877,7,0,7]
["S9152","Epiberberine","g7","L4000-15","in 10mM DMSO","Others","Others","Epiberberine, a natural protoberberine alkaloid, is a potent inhibitor against both ureases with IC50 values of 3.0±0.01μM for HPU (ureases from Helicobacter pylori) and 2.3±0.01μM for JBU (ureases from jack bean).",336.36,"6873-09-2",{"v":12,"d":"12.00"},35.68,"N/A","N/A","https://www.selleckchem.com/products/epiberberine.html","C20H18NO4","free base","N/A","COC1=C(OC)C=C2C(=C1)CC[N+]3=C2C=C4C=CC5=C(OCO5)C4=C3",3.962,4,0,2]
["S9154","Chelidonine","h7","L4000-15","in 10mM DMSO","AChR","Neuronal Signaling","Chelidonine (Stylophorin, Helidonine), a major bioactive, isoquinoline alkaloid ingredient in Chelidonium majus, exhibits anti-inflammatory properties and acetylcholinesterase and butyrylcholinesterase inhibitory activity.",353.37,"476-32-4",{"v":5,"d":"5.00"},14.15,"N/A","N/A","https://www.selleckchem.com/products/chelidonine.html","C20H19NO5","free base","Stylophorin, Helidonine","CN1CC2=C(C=CC3=C2OCO3)C4C(O)CC5=C(C=C6OCOC6=C5)C14",2.329,4,1,0]
["S9173","Sec-O-Glucosylhamaudol","a8","L4000-15","in 10mM DMSO","Others","Others","Sec-O-Glucosylhamaudol (Hamaudol 3-glucoside) is one of the major bioactive compounds of the Saposhnikoviae Radix.",438.43,"80681-44-3",{"v":88,"d":"88.00"},200.72,"N/A","N/A","https://www.selleckchem.com/products/sec-o-glucosylhamaudol.html","C21H26O10","free base","Hamaudol 3-glucoside","CC1=CC(=O)C2=C(O)C3=C(OC(C)(C)C(C3)OC4OC(CO)C(O)C(O)C4O)C=C2O1",0.042,5,5,3]
["S9174","Xanthotoxol","b8","L4000-15","in 10mM DMSO","5-HT Receptor,Immunology & Inflammation related","Neuronal Signaling","Xanthotoxol (8-Hydroxypsoralen, 8-Hydroxypsoralene, 8-Hydroxyfuranocoumarin, Psoralen), a biologically active linear furocoumarin found in a large number of plants, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.",202.16,"2009-24-7",{"v":40,"d":"40.00"},197.86,"N/A","N/A","https://www.selleckchem.com/products/xanthotoxol.html","C11H6O4","free base","8-Hydroxypsoralen, 8-Hydroxypsoralene, 8-Hydroxyfuranocoumarin, Psoralen","OC1=C2OC(=O)C=CC2=CC3=C1OC=C3",1.961,3,1,0]
["S9176","Pimpinellin","c8","L4000-15","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Pimpinellin is a furocoumarin that acts as antagonist of proteins with GABA receptor activity.",246.22,"131-12-4",{"v":49,"d":"49.00"},199.01,"N/A","N/A","https://www.selleckchem.com/products/pimpinellin.html","C13H10O5","free base","N/A","COC1=C(OC)C2=C(OC(=O)C=C2)C3=C1OC=C3",{"v":2.17,"d":"2.170"},5,0,2]
["S9178","Sinapine thiocyanate","d8","L4000-15","in 10mM DMSO","Others","Immunology & Inflammation","Sinapine thiocyanate is the thiocyanate salt form of Sinapine, which shows favorable biological activities such as antioxidant and radio-protective activities.",368.45,"7431-77-8",{"v":73,"d":"73.00"},198.13,"N/A","N/A","https://www.selleckchem.com/products/sinapine-thiocyanate.html","C17H24N2O5S","free base","N/A","COC1=CC(=CC(=C1O)OC)/C=C/C(=O)OCC[N+](C)(C)C.[S-]C#N",1.287,4,1,8]
["S9179","Catharanthine hemitartrate","e8","L4000-15","in 10mM DMSO","AChR","Neuronal Signaling","Catharanthine hemitartrate is the starting material for the synthesis of the antitumor drugs vinblastine and vincristine.",822.94,"4168-17-6",{"v":97,"d":"97.00"},199.38,"N/A","N/A","https://www.selleckchem.com/products/catharanthine-hemitartrate.html","C46H54N4O10","free base","N/A","CCC1=CC2CN3CCC4=C([NH]C5=C4C=CC=C5)C(C2)(C13)C(=O)OC.OC(C(O)C(O)=O)C(O)=O",-0.822,4,3,6]
["S9184","Forsythoside B","f8","L4000-15","in 10mM DMSO","Immunology & Inflammation related,Interleukins,IκB/IKK,NF-κB,TNF-alpha","Immunology & Inflammation","Forsythoside B is a phenylethanoid glycoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant. Forsythoside B has potent neuroprotective effects and has anti-inflammation, antioxidant, and antisepsis properties. Forsythoside B could inhibit TNF-alpha, IL-6, IκB and modulate NF-κB.",{"v":756.7,"d":"756.70"},"81525-13-5",{"v":100,"d":"100.00"},132.15,"N/A","N/A","https://www.selleckchem.com/products/forsythoside-b.html","C34H44O19","free base","N/A","CC1OC(OC2C(O)C(OCCC3=CC=C(O)C(=C3)O)OC(COC4OCC(O)(CO)C4O)C2OC(=O)/C=C/C5=CC(=C(O)C=C5)O)C(O)C(O)C1O",-0.925,8,10,14]
["S9190","Oroxin B","g8","L4000-15","in 10mM DMSO","Akt,Apoptosis related,COX,PI3K,PTEN","Apoptosis","Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels are downregulated, while PTEN is upregulated after Oroxin B treatment.",594.52,"114482-86-9",{"v":100,"d":"100.00"},{"v":168.2,"d":"168.20"},"N/A","N/A","https://www.selleckchem.com/products/oroxin-b.html","C27H30O15","free base","Hypocretin-2","OCC1OC(OCC2OC(OC3=C(O)C(=C4C(=O)C=C(OC4=C3)C5=CC=CC=C5)O)C(O)C(O)C2O)C(O)C(O)C1O",-1.267,6,9,7]
["S9201","Levistilide A","h8","L4000-15","in 10mM DMSO","P-gp","Neuronal Signaling","Levistilide A (Diligustilide), a natural compound isolated from the traditional Chinese herb Ligusticum chuanxiong Hort, is a potential P-gp modulator and used for treating cancer.",380.48,"88182-33-6",{"v":76,"d":"76.00"},199.75,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/levistilide-a.html","C24H28O4","Free Base","Diligustilide","CCC/C=C/1OC(=O)C2=C1CCC3C4CCC5(C23)\\C(OC(=O)C5=C4)=C\\CCC",{"v":4.97,"d":"4.970"},4,0,4]
["S9219","Huperzine B","a9","L4000-15","in 10mM DMSO","AChR","Neuronal Signaling","Huperzine B, a natural alkaloid existed in Lycopodium plants, is a novel acetylcholinesterase inhibitor and has neuroprotective effects.",256.34,"103548-82-9",{"v":10,"d":"10.00"},39.01,"N/A","N/A","https://www.selleckchem.com/products/huperzine-b.html","C16H20N2O","free base","N/A","CC1=CC2CC3=C(C=CC(=O)N3)C4(C1)NCCCC24",1.259,1,2,0]
["S9236","α-Cyperone","b9","L4000-15","in 10mM DMSO","COX,Interleukins","Immunology & Inflammation","α-Cyperone (alpha-cyperone), a major active compound of Cyperus rotundus, exhibits biological activities, such as antivirulence, antigenotoxic, and antibacterial activities. α-Cyperone (alpha-cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1.",218.33,"473-08-5","N/A","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","https://www.selleckchem.com/products/alpha-cyperone.html","C15H22O","free base","N/A","CC(=C)C1CCC2(C)CCC(=O)C(=C2C1)C",3.946,1,0,1]
["S9239","Isocorynoxeine","c9","L4000-15","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Isocorynoxeine (7-Isocorynoxeine), a major alkaloid found in Uncaria rhynchophylla, exhibits wide beneficial effects on the cardiovascular and cardiocerebral vascular systems. Isocorynoxeine suppress 5-HT2A receptor-mediated current response with IC50 of 72.4 μM.",382.45,"51014-29-0",{"v":77,"d":"77.00"},201.33,"N/A","N/A","https://www.selleckchem.com/products/isocorynoxeine.html","C22H26N2O4","free base","7-Isocorynoxeine","CO\\C=C(/C1CC2N(CCC23C(=O)NC4=CC=CC=C34)CC1C=C)C(=O)OC",1.712,4,1,5]
["S9243","Protosappanin B","d9","L4000-15","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Protosappanin B (FT-0689654, Q-100961), extracted from Lignum Sappan, possesses anti-inflammation and anti-oxidation properties.",304.29,"102036-29-3",{"v":61,"d":"61.00"},200.46,"N/A","N/A","https://www.selleckchem.com/products/protosappanin-b.html","C16H16O6","free base","FT-0689654, Q-100961","OCC1(O)COC2=CC(=CC=C2C3=CC(=C(O)C=C3C1)O)O",1.486,1,4,1]
["S9249","Securinine","e9","L4000-15","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Securinine, a major natural alkaloid product from the root of the plant Securinega suffruticosa, acts as a γ-amino butyric acid (GABA) receptor antagonist.",217.26,"5610-40-2",{"v":44,"d":"44.00"},202.52,"N/A","N/A","https://www.selleckchem.com/products/securinine.html","C13H15NO2","free base","N/A","O=C1OC23CC(C=CC2=C1)N4CCCCC34",1.449,2,0,0]
["S9252","Corydaline","f9","L4000-15","in 10mM DMSO","AChR","Neuronal Signaling","Corydaline is a bioactive alkaloid with various anti-acetylcholinesterase, anti-allergic, and anti-nociceptive activities found in the medicinal herb Corydalis Tubers.",369.45,"518-69-4",{"v":74,"d":"74.00"},{"v":200.3,"d":"200.30"},"N/A","N/A","https://www.selleckchem.com/products/corydaline.html","C22H27NO4","free base","N/A","COC1=CC2=C(C=C1OC)C3C(C)C4=C(CN3CC2)C(=C(OC)C=C4)OC",3.918,4,0,4]
["S9253","Coixol","g9","L4000-15","in 10mM DMSO","Others","Others","Coixol (6-methoxybenzoxazolone, MBOA) acts as a central muscle relaxant with an anti-convulsant effect.",165.15,"532-91-2",{"v":33,"d":"33.00"},199.82,"N/A","N/A","https://www.selleckchem.com/products/coixol.html","C8H7NO3","free base","6-methoxybenzoxazolone, MBOA","COC1=CC2=C(NC(=O)O2)C=C1",1.323,3,1,1]
["S9256","Isobavachin","h9","L4000-15","in 10mM DMSO","Others","Others","Isobavachin is a flavonoid compound obtained from Psoralea Corylifolia Linn.",324.37,"31524-62-6",{"v":65,"d":"65.00"},200.39,"N/A","N/A","https://www.selleckchem.com/products/isobavachin.html","C20H20O4","free base","N/A","CC(C)=CCC1=C2OC(CC(=O)C2=CC=C1O)C3=CC=C(O)C=C3",4.472,2,2,3]
["S9258","(+)-Isocorynoline","a10","L4000-15","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Isocorynoxeine, a major bioactive tetracyclic oxindole alkaloids found in Uncaria rhynchophylla, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM and shows various beneficial effects, including lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage.",{"v":341.4,"d":"341.40"},"475-67-2",{"v":32,"d":"32.00"},93.73,"N/A","N/A","https://www.selleckchem.com/products/isocorynoline.html","C20H23NO4","free base","N/A","COC1=C(O)C2=C(CC3N(C)CCC4=C3C2=C(OC)C(=C4)OC)C=C1",3.308,3,1,3]
["S9260","Nodakenin","b10","L4000-15","in 10mM DMSO","AChR","Neuronal Signaling","Nodakenin ((+)-Marmesinin), a coumarin compound, acts as an AChE inhibitor that inhibits AChE activity in a dosedependent manner with an IC50 value of 84.7 μM.",{"v":408.4,"d":"408.40"},"495-31-8",{"v":82,"d":"82.00"},200.78,"N/A","N/A","https://www.selleckchem.com/products/nodakenin.html","C20H24O9","free base","(+)-Marmesinin","CC(C)(OC1OC(CO)C(O)C(O)C1O)C2CC3=CC4=C(OC(=O)C=C4)C=C3O2",0.282,5,4,4]
["S9263","3-n-Butylphathlide","c10","L4000-15","in 10mM DMSO","Others","Others","3-n-Butylphathlide, initially isolated from the seeds of Apium graveolens Linn., has shown significant neuroprotective effects.",190.24,"6066-49-5","N/A","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","https://www.selleckchem.com/products/3-n-butylphathlide.html","C12H14O2","free base","N/A","CCCCC1OC(=O)C2=C1C=CC=C2",3.252,2,0,3]
["S9272","Koumine","d10","L4000-15","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Koumine, a Gelsemium alkaloid, possesses analgesic, anti-inflammatory and neurosteroid modulating activities.",{"v":306.4,"d":"306.40"},"1358-76-5",{"v":15,"d":"15.00"},48.96,"N/A","N/A","https://www.selleckchem.com/products/koumine.html","C20H22N2O","free base","N/A","CN1CC2(C=C)C3CC4OCC3C1CC25C4=NC6=CC=CC=C56",1.879,2,0,1]
["S9293","Isoliquiritin","e10","L4000-15","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Isoliquiritin (Neoisoliquritin) is a flavonoid glycoside compound from licorice possessing a broad spectrum of pharmacological activities including antioxidant, anti-inflammatory, and anti-depression activities.",418.39,"5041-81-6",{"v":84,"d":"84.00"},200.77,"N/A","N/A","https://www.selleckchem.com/products/isoliquiritin.html","C21H22O9","free base","Neoisoliquritin","OCC1OC(OC2=CC=C(\\C=C\\C(=O)C3=C(O)C=C(O)C=C3)C=C2)C(O)C(O)C1O",1.046,3,6,6]
["S9295","Dauricine","f10","L4000-15","in 10mM DMSO","NF-κB","NF-κB","Dauricine, a plant metabolite isolated from the Asian vine Menispermum dauricum, plays a variety of biological roles in the human body, from inhibiting cancer cell growth to blocking cardiac transmembrane Na+, K+, and Ca2+ ion currents.Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF‐κB signaling pathway in colon cancer cells.",624.77,"524-17-4",{"v":100,"d":"100.00"},160.06,"N/A","N/A","https://www.selleckchem.com/products/dauricine.html","C38H44N2O6","free base","N/A","COC1=CC2=C(C=C1OC)C(CC3=CC=C(OC4=C(O)C=CC(=C4)CC5N(C)CCC6=C5C=C(OC)C(=C6)OC)C=C3)N(C)CC2",7.245,5,1,10]
["S9309","Micheliolide","g10","L4000-15","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Micheliolide, a sesquiterpene lactone isolated from Michelia compressa and Michelia champaca, inhibits various inflammatory response and may serve as a neuroprotective agent in neuroinflammation-related neurodegenerative disorders.",248.32,"68370-47-8",{"v":49,"d":"49.00"},197.33,"N/A","N/A","https://www.selleckchem.com/products/micheliolide.html","C15H20O3","free base","N/A","CC1=C2CCC(C)(O)C2C3OC(=O)C(=C)C3CC1",{"v":2.34,"d":"2.340"},2,0,0]
["S9310","Isorhychophylline","h10","L4000-15","in 10mM DMSO","Autophagy","Autophagy","Isorhynchophylline (IsoRhy, 7-Isorhyncophylline) is a major tetracyclic oxindole alkaloid isolated from the Chinese herbal medicine Uncaria rhynchophylla (Miq.)Jacks (Gouteng in Chinese). It acts as a neuronal autophagy inducer with therapeutic potential for cardiovascular and central nervous system diseases.",384.47,"6859-01-4",{"v":77,"d":"77.00"},200.28,"N/A","N/A","https://www.selleckchem.com/products/isorhychophylline.html","C22H28N2O4","free base","IsoRhy, 7-Isorhyncophylline","CCC1CN2CCC3(C2CC1\\C(=C/OC)C(=O)OC)C(=O)NC4=CC=CC=C34",2.103,4,1,5]
["S9312","Cyanidin-3-O-glucoside chloride","a11","L4000-15","in 10mM DMSO","Others","Others","Cyanidin-3-O-glucoside chloride (Kuromanin, Chrysontemin, Glucocyanidin) is a natural product with anti-oxidant and neuroprotective effects.",484.84,"7084-24-4",{"v":97,"d":"97.00"},200.07,"N/A","N/A","https://www.selleckchem.com/products/cyanidin-3-o-glucoside-chloride.html","C21H21ClO11","free base","Kuromanin chloride, Chrysontemin chloride, Glucocyanidin chloride","[Cl-].OCC1OC(OC2=C([O+]=C3C=C(O)C=C(O)C3=C2)C4=CC(=C(O)C=C4)O)C(O)C(O)C1O",-1.566,2,8,4]
["S9313","Atractylenolide III","b11","L4000-15","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Atractylenolide III, a major component of Atractylodes rhizome, has anti-inflammatory and anti-angiogenesis activities.",248.32,"73030-71-4",{"v":50,"d":"50.00"},201.36,"N/A","N/A","https://www.selleckchem.com/products/atractylenolide-iii.html","C15H20O3","free base","N/A","CC1=C2CC3C(=C)CCCC3(C)CC2(O)OC1=O",2.924,2,0,0]
["S9314","Atractylenolide II","c11","L4000-15","in 10mM DMSO","Others","Others","Atractylenolide II (AT-II, Asterolide, 2-Atractylenolide), a major sesquiterpenoids isolated from the dried Rhizome of Atractylodes macrocephala, shows a wide range of biological and pharmacological activities, for example, against insomnia and anxiety, neuroprotective, platelet activation and anti-cancer effect.",232.32,"73069-14-4",{"v":46,"d":"46.00"},{"v":198,"d":"198.00"},"N/A","N/A","https://www.selleckchem.com/products/atractylenolide-ii.html","C15H20O2","free base","Asterolide, 2-Atractylenolide","CC1=C2CC3C(=C)CCCC3(C)CC2OC1=O",3.573,2,0,0]
["S9315","Praeruptorin A","d11","L4000-15","in 10mM DMSO","Akt,Calcium Channel,p38 MAPK","PI3K/Akt/mTOR","Praeruptorin A, a naturally existing pyranocumarin, is isolated from the dried root of Peucedanum praeruptorum Dunn. Praeruptorin A inhibits p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca2+ oscillation. Praeruptorin A can significantly upregulates multidrug resistance-associated protein 2 expression via the constitutive androstane receptor-mediated pathway in vitro, and this should be taken as an herb-drug interaction.",{"v":386.4,"d":"386.40"},"73069-25-7",{"v":77,"d":"77.00"},199.28,"N/A","N/A","https://www.selleckchem.com/products/praeruptorin-a-1.html","C21H22O7","free base","N/A","C\\C=C(C)/C(=O)OC1C(OC(C)=O)C2=C(OC1(C)C)C=CC3=C2OC(=O)C=C3",3.502,7,0,5]
["S9326","Scopolamine","e11","L4000-15","in 10mM DMSO","AChR","Neuronal Signaling","Scopolamine (Skopolamin) is a tropane alkaloid derived from plants of the nightshade family, specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic and antivertigo properties.",303.35,"51-34-3","N/A","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","https://www.selleckchem.com/products/scopolamine.html","C17H21NO4","free base","Skopolamin","CN1C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",0.823,3,1,5]
["S9348","D-(+)-Trehalose Anhydrous","f11","L4000-15","in 10mM DMSO","Others","Others","Trehalose is a non-reducing sugar. It is thought to provide plants and animals with the ability to withstanding periods of dehydration.",{"v":342.3,"d":"342.30"},"99-20-7",{"v":68,"d":"68.00"},198.66,"N/A","N/A","https://www.selleckchem.com/products/d-trehalose-anhydrous.html","C12H22O11","free base","N/A","OCC1OC(OC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O",-4.261,3,8,4]
["S9350","Ethyl 4-Methoxycinnamate","g11","L4000-15","in 10mM DMSO","Fungal","Microbiology","Ethyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities.",206.24,"24393-56-4",{"v":41,"d":"41.00"},{"v":198.8,"d":"198.80"},"N/A","N/A","https://www.selleckchem.com/products/ethyl-4-methoxycinnamate.html","C12H14O3","free base","Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester, Ethyl methoxycinnamate, Ethyl para-methoxycinnamate","CCOC(=O)\\C=C\\C1=CC=C(OC)C=C1",2.485,3,0,5]
["S9361","Coumarin-3-carboxylic acid","h11","L4000-15","in 10mM DMSO","Others","Others","Coumarin-3-carboxylic acid is used as a detector for hydroxyl radicals (.OH) in aqueous solution.",190.15,"531-81-7",{"v":38,"d":"38.00"},199.84,"N/A","N/A","https://www.selleckchem.com/products/coumarin-3-carboxylic-acid.html","C10H6O4","free base","N/A","OC(=O)C1=CC2=C(OC1=O)C=CC=C2",1.489,3,0,1]
["S9377","Eugenyl acetate","a2","L4000-16","in 10mM DMSO","Bacterial","Microbiology","Eugenyl acetate, an aromatic component of clove essential oil, exhibits various pharmacological activities, including antibacterial and anti-virulence activities against drug-resistant A. baumannii clinical isolates.",206.24,"93-28-7","N/A","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","https://www.selleckchem.com/products/eugenyl-acetate.html","C12H14O3","free base","N/A","COC1=C(OC(C)=O)C=CC(=C1)CC=C",2.589,3,0,5]
["S9400","Rhynchophylline","b2","L4000-16","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Rhynchophylline (Mitrinermine), an active component isolated from species of the genus Uncaria, acts as a calcium channel blocker and is widely used in traditional Chinese medicine mainly for treating ailments of central nervous and cardiovascular systems, such as lightheadedness, convulsions, numbness, and hypertension.",384.47,"76-66-4",{"v":76,"d":"76.00"},197.68,"N/A","N/A","https://www.selleckchem.com/products/rhynchophylline.html","C22H28N2O4","free base","Mitrinermine","CCC1CN2CCC3(C2CC1\\C(=C/OC)C(=O)OC)C(=O)NC4=CC=CC=C34",2.103,4,1,5]
["S9401","3,6'-Disinapoyl sucrose","c2","L4000-16","in 10mM DMSO","Others","Others","3,6'-Disinapoyl sucrose (Disinapoyl sucrose), an oligosaccharide ester natural product originating from the root of wild Polygala tenuifolia, has neuroprotective effects and antidepressive activity in rats.",754.69,"139891-98-8",{"v":100,"d":"100.00"},132.51,"N/A","N/A","https://www.selleckchem.com/products/3-6-disinapoyl-sucrose.html","C34H42O19","free base","Disinapoyl sucrose","COC1=CC(=CC(=C1O)OC)\\C=C\\C(=O)OCC2OC(OC3(CO)OC(CO)C(O)C3OC(=O)/C=C/C4=CC(=C(O)C(=C4)OC)OC)C(O)C(O)C2O",0.162,11,8,17]
["S9408","Beta-Elemonic acid","d2","L4000-16","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Beta-Elemonic acid (3-Oxotirucallenoic Acid), a known triterpene isolated from Boswellia (Burseraceae), exhibits anti‑inflammatory effects.",454.68,"28282-25-9",{"v":35,"d":"35.00"},76.98,"N/A","N/A","https://www.selleckchem.com/products/beta-elemonic.html","C30H46O3","free base","3-Oxotirucallenoic Acid","CC(C)=CCCC(C1CCC2(C)C3=C(CCC12C)C4(C)CCC(=O)C(C)(C)C4CC3)C(O)=O",7.153,2,0,5]
["S9409","Kavain","e2","L4000-16","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Kavain ((+)-Kavain), the main kavalactone found mostly in the roots of the kava plant, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor.",230.26,"500-64-1",{"v":46,"d":"46.00"},199.77,"N/A","N/A","https://www.selleckchem.com/products/kavain.html","C14H14O3","free base","(+)-Kavain","COC1=CC(=O)OC(C1)\\C=C\\C2=CC=CC=C2",2.218,3,0,3]
["S9413","Yangonin","f2","L4000-16","in 10mM DMSO","Cannabinoid Receptor,Fungal","GPCR & G Protein","Yangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors.",258.27,"500-62-9",{"v":51,"d":"51.00"},197.47,"N/A","N/A","https://www.selleckchem.com/products/yangonin.html","C15H14O4","free base","Y100550","COC1=CC=C(C=C1)/C=C/C2=CC(=CC(=O)O2)OC",2.211,4,0,4]
["S9418","Parishin B","g2","L4000-16","in 10mM DMSO","Others","Others","Parishin B is a dominant active ingredient originating from Gastrodia elata Blume, and has good neuroprotective effects against brain disorders.",728.65,"174972-79-3",{"v":100,"d":"100.00"},137.24,"N/A","N/A","https://www.selleckchem.com/products/parishin-b.html","C32H40O19","free base","N/A","OCC1OC(OC2=CC=C(COC(=O)CC(O)(CC(O)=O)C(=O)OCC3=CC=C(OC4OC(CO)C(O)C(O)C4O)C=C3)C=C2)C(O)C(O)C1O",-2.045,9,8,17]
["S9427","Tabersonine","h2","L4000-16","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Tabersonine is a terpene indole alkaloid found in the medicinal plant Catharanthus roseus and shows hypotensive activity, anti-tumor activity, hypoglycemic, diuretic activity.",336.43,"4429-63-4",{"v":67,"d":"67.00"},199.15,"N/A","N/A","https://www.selleckchem.com/products/tabersonine.html","C21H24N2O2","free base","N/A","CCC12CC(=C3NC4=C(C=CC=C4)C35CCN(CC=C1)C25)C(=O)OC",2.807,2,1,3]
["S9428","Brazilin","a3","L4000-16","in 10mM DMSO","Beta Amyloid","Neuronal Signaling","Brazilin (Natural Red 24) is a red pigment obtained from the wood of the brazilwood family. It is used to dye fabric and has diverse biological activities, including neuroprotective, anti-inflammatory, antibacterial, and antioxidant properties.",286.28,"474-07-7",{"v":57,"d":"57.00"},199.11,"N/A","N/A","https://www.selleckchem.com/products/brazilin.html","C16H14O5","free base","Natural Red 24","OC1=CC2=C(C=C1)C3C4=CC(=C(O)C=C4CC3(O)CO2)O",1.933,1,3,0]
["S9434","8-Gingerol","b3","L4000-16","in 10mM DMSO","Others","Others","8-Gingerol is a bioactive ingredient of ginger root (Zingiber officinale), a medicinal plant having anti-nausea, anti-inflammatory, and anti-carcinogenic properties and a carminative effect.",322.44,"23513-08-8",{"v":64,"d":"64.00"},198.49,"N/A","N/A","https://www.selleckchem.com/products/8-gingerol.html","C19H30O4","free base","N/A","CCCCCCCC(O)CC(=O)CCC1=CC=C(O)C(=C1)OC",4.551,2,2,12]
["S9443","Schisantherin B","c3","L4000-16","in 10mM DMSO","Others","Others","Schisantherin B (Gomisin-B, Wuweizi ester-B) is one bioactive of lignans isolated from Schisandra chinensis (Turcz.) Baill which has been commonly used as a traditional herbal medicine.",514.56,"58546-55-7",{"v":100,"d":"100.00"},194.34,"N/A","N/A","https://www.selleckchem.com/products/schisantherin-b.html","C28H34O9","free base","Gomisin-B, Wuweizi ester-B","COC1=C(OC)C(=C2C(=C1)C(OC(=O)\\C(C)=C/C)C(C)(O)C(C)CC3=C2C(=C4OCOC4=C3)OC)OC",4.944,8,0,7]
["S9446","7,8-dihydrokawain","d3","L4000-16","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","7,8-dihydrokawain is a kavalactone source from kava beverages used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.",232.28,"587-63-3",{"v":46,"d":"46.00"},198.04,"N/A","N/A","https://www.selleckchem.com/products/dihydrokavain.html","C14H16O3","free base","Marindinin","COC1=CC(=O)OC(CCC2=CC=CC=C2)C1",2.528,3,0,4]
["S9457","Phensuximide","e3","L4000-16","in 10mM DMSO","cAMP/cGMP","Neuronal Signaling","Phensuximide is an orally active succinimide antiepileptic and anticonvulsant agent. Phensuximide inhibits cyclic AMP and cyclic GMP accumulation in depolarized brain tissue. Phensuximide can be used for the study of seizure and petit mal.",189.21,"86-34-0",{"v":38,"d":"38.00"},200.84,{"v":-1,"d":"-1.00"},"N/A","N/A","C11H11NO2","Free Base","N/A","CN1C(=O)CC(C1=O)C2=CC=CC=C2",0.908,2,0,1]
["S9459","Mecamylamine Hydrochloride","f3","L4000-16","in 10mM DMSO","AChR","Neuronal Signaling","Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist. Mecamylamine hydrochloride is also a ganglionic blocker. Mecamylamine hydrochloride can across the blood-brain barrier. Mecamylamine hydrochloride can be used in the research of neuropsychiatric disorders, hypertension, antidepressant area.",203.75,"826-39-1",{"v":41,"d":"41.00"},201.23,{"v":-1,"d":"-1.00"},"N/A","N/A","C11H21N · HCl","Hydrochloride","N/A","Cl.CNC1(C)C2CCC(C2)C1(C)C",2.565,0,1,1]
["S9460","Ethotoin","g3","L4000-16","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Ethotoin (Peganone) is an orally active anticonvulsant agent used in epilepsy research. Ethotoin inhibits nerve impulses in the motor cortex by lowering sodium ion influx, limiting tetanic stimulation.",204.23,"86-35-1",{"v":41,"d":"41.00"},200.75,{"v":-1,"d":"-1.00"},"N/A","N/A","C11H12N2O2","Free Base","N/A","CCN1C(=O)NC(C1=O)C2=CC=CC=C2",1.113,2,1,2]
["S9461","Benzonatate","h3","L4000-16","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Benzonatate(Benzononatine)  has sodium channel-blocking properties and local anesthetic effects on the respiratory stretch receptors due to a tetracaine-like metabolite.",603.74,"32760-16-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","https://www.selleckchem.com/products/benzonatate.html","(C2H4O)nC12H17NO2","Free Base","Benzononatine","CCCCNC1=CC=C(C=C1)C(=O)OCCOC",3.426,3,1,9]
["S9463","Demecarium Bromide","a4","L4000-16","in 10mM DMSO","AChR","Neuronal Signaling","Demecarium Bromide (BC-48) is a potent cholinesterase inhibitor, with an apparent affinity (Kiapp) of 0.15 μM. Demecarium Bromide (BC-48) is used as a glaucoma agent.",716.59,"56-94-0",{"v":100,"d":"100.00"},139.55,{"v":-1,"d":"-1.00"},"N/A","N/A","C32H52Br2N4O4","Bromide","N/A","[Br-].[Br-].CN(CCCCCCCCCCN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C)C(=O)OC2=CC=CC(=C2)[N+](C)(C)C",-0.615,4,0,17]
["S9467","Thiothixene","b4","L4000-16","in 10mM DMSO","Dopamine receptor & Adrenergic receptor","Neuronal Signaling","Thiothixene is an antipsychotic thioxanthene used for the management of schizophrenia. It has antagonistic effects on dopaminergic-receptor and alpha-adrenergic receptor.",443.63,"3313-26-6",{"v":5,"d":"5.00"},11.27,{"v":-1,"d":"-1.00"},"N/A","N/A","C23H29N3O2S2","Free Base","N/A","CN1CCN(CC\\C=C/2C3=C(SC4=C2C=C(C=C4)[S](=O)(=O)N(C)C)C=CC=C3)CC1",3.533,2,0,5]
["S9469","Haloperidol Decanoate","c4","L4000-16","in 10mM DMSO","D2R","Neuronal Signaling","Haloperidol Decanoate is an antipsychotic drug used for the management of schizophrenia. It has antagonistic effects on dopamine 2 receptor.",530.11,"74050-97-8",{"v":100,"d":"100.00"},188.64,{"v":-1,"d":"-1.00"},"N/A","N/A","C31H41ClFNO3","Decanoate","N/A","CCCCCCCCCC(=O)OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C3=CC=C(Cl)C=C3",8.127,3,0,16]
["S9470","Penbutolol Sulfate","d4","L4000-16","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Penbutolol sulfate ((-)-Terbuclomine) is an effective beta-adrenergic receptor blocker and diuretic that is used as an antihypertensive agent.",680.94,"38363-32-5",{"v":15,"d":"15.00"},22.03,{"v":-1,"d":"-1.00"},"N/A","https://www.selleckchem.com/products/penbutolol-sulfate.html","C18H29NO2.1/2H2O4S","Sulfate","(-)-Terbuclomine","CC(C)(C)NCC(O)COC1=C(C=CC=C1)C2CCCC2.CC(C)(C)NCC(O)COC3=C(C=CC=C3)C4CCCC4.O[S](O)(=O)=O",6.536,2,4,14]
["S9472","Oxtriphylline","e4","L4000-16","in 10mM DMSO","PDE Inhibitor, Adenosine receptor, & Histone deacetylase","Metabolism","Oxtriphylline is a choline salt of theophylline with anti-asthmatic activity (bronchodilator). The theophylline, upon release, acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator.",283.33,"4499-40-5",{"v":15,"d":"15.00"},52.94,{"v":-1,"d":"-1.00"},"N/A","N/A","C12H21N5O3","Free Base","N/A","CN1C(=O)N(C)C2=C([N-]C=N2)C1=O.C[N+](C)(C)CCO",-1.714,3,1,2]
["S9475","Hupehenine","f4","L4000-16","in 10mM DMSO","AChR","Neuronal Signaling","Hupehenine is a steriodal alkaloid extracted from the bulbs of Fritillaria Hupehensis, with the potential for inhibiting acetylcholine, antagonism for muscarinic receptors and cholinesterase inhibition.",415.65,"98243-57-3",{"v":5,"d":"5.00"},12.03,{"v":1,"d":"1.00"},2.41,"http://www.selleckchem.com/products/hupehenine.html","C27H45NO2","Free Base","N/A","CC1CCC2C(C)C3CCC4C(CC5C4CC(O)C6CC(O)CCC56C)C3CN2C1",{"v":4.41,"d":"4.410"},0,2,0]
["S9487","Praeruptorin C","g4","L4000-16","in 10mM DMSO","Others","Others","Praeruptorin C is a natural compound derived from the dried roots of Peucedanum praeruptorum and has beneficial effects in suppressing osteoclast formation and resorption function. It is frequently utilized in traditional Chinese medicine for treating upper respiratory infections and as an antipyretic, antitussive, and mucolytic agent.",428.47,"72463-77-5",{"v":86,"d":"86.00"},200.71,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/praeruptorin-c.html","C24H28O7","Free Base","N/A","C\\C=C(C)/C(=O)OC1C(OC(=O)CC(C)C)C2=C(OC1(C)C)C=CC3=C2OC(=O)C=C3",4.877,7,0,7]
["S9502","Madecassic acid","h4","L4000-16","in 10mM DMSO","COX,Immunology & Inflammation related,Interleukins,NF-κB,NOS,TNF-alpha","Immunology & Inflammation","Madecassic acid (Brahmic acid), a natural triterpene first isolated from C. asiatica, has diverse anti-inflammatory and anti-diabetic effects, blocking NF-κB activation in macrophages and causing by iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 inhibition.",{"v":504.7,"d":"504.70"},"18449-41-7",{"v":100,"d":"100.00"},198.13,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/madecassic-acid.html","C30H48O6","Free Base","Brahmic acid","CC1CCC2(CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(CO)C5C(O)CC34C)C2C1C)C(O)=O",3.265,1,4,2]
["S9507","(−)-Norepinephrine","a5","L4000-16","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","(−)-Norepinephrine (Arterenol, Levarterenol, L-Noradrenaline) is a natural neurotransmitter and hormone. It is an agonist of adrenergic receptors with Ki values of 330, 56, and 740 nM for α1, α2, and β1 adrenoceptors, respectively.",169.18,"51-41-2",{"v":11,"d":"11.00"},65.02,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/norepinephrine.html","C8H11NO3","Free Base","Arterenol, Levarterenol, L-Noradrenaline","NCC(O)C1=CC(=C(O)C=C1)O",-0.059,0,4,2]
["S9508","Brimonidine","b5","L4000-16","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Brimonidine (Bromoxidine, UK 1430) is an alpha adrenergic receptor agonist (primarily alpha-2) and is used for the treatment of open-angle glaucoma or ocular hypertension to lower intraocular pressure.",292.13,"59803-98-4",{"v":26,"d":"26.00"},{"v":89,"d":"89.00"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/brimonidine.html","C11H10BrN5","Free Base","Bromoxidine, UK 14304","BrC1=C(NC2=NCCN2)C=CC3=C1N=CC=N3",1.237,3,2,2]
["S9509","Tiapride Hydrochloride","c5","L4000-16","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Tiapride is a drug that selectively blocks D2 and D3 dopamine receptors in the brain and is used to treat a variety of neurological and psychiatric disorders.",364.89,"51012-33-0",{"v":35,"d":"35.00"},95.92,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/tiapride-hydrochloride.html","C15H25ClN2O4S","hydrochloride","N/A","Cl.CCN(CC)CCNC(=O)C1=CC(=CC=C1OC)[S](C)(=O)=O",1.766,4,1,8]
["S9510","Protriptyline hydrochloride","d5","L4000-16","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline. Protriptyline is a tricyclic secondary amine with antidepressant property which acts by inhibition of serotonin and norepinephrine reuptake.",299.84,"1225-55-4",{"v":60,"d":"60.00"},200.11,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/protriptyline-hydrochloride.html","C19H22ClN","hydrochloride","N/A","Cl.CNCCCC1C2=C(C=CC=C2)C=CC3=C1C=CC=C3",4.423,0,1,4]
["S9511","Crocin I","e5","L4000-16","in 10mM DMSO","Others","Metabolism","Crocin-I, a major member of the crocin family, has antidepressant activity and ameliorates the disruption of lipid metabolism and dysbiosis of the gut microbiota induced by chronic corticosterone in mice.",976.96,"94238-00-3",{"v":100,"d":"100.00"},102.36,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/crocin-i.html","C44H64O24","Free Base","N/A","CC(=C/C=C/C=C(C)/C=C/C=C(C)/C(=O)OC1OC(COC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O)\\C=C\\C=C(C)\\C(=O)OC3OC(COC4OC(CO)C(O)C(O)C4O)C(O)C(O)C3O",-2.722,10,14,20]
["S9560","Anisodamine Hydrobromide","f5","L4000-16","in 10mM DMSO","AChR,Adrenergic Receptor,Anti-infection,Immunology & Inflammation related","Immunology & Inflammation","Anisodamine (6-Hydroxyhyoscyamine) is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs).",386.28,"55449-49-5",{"v":77,"d":"77.00"},199.34,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/anisodamine-hydrobromide.html","C17H24BrNO4","Hydrobromide","6-Hydroxyhyoscyamine","Br.CN1C2CC(O)C1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",1.121,2,2,5]
["S9563","Evodine","g5","L4000-16","in 10mM DMSO","P-gp","Transmembrane Transporters","Evodine, a natural product extracted from Evodiae fructus (EF), is a biomarker for quality assessment of EF in the Chinese Pharmacopoeia. Evodine is a potent P-gp inhibitor.",329.35,"6989-38-4",{"v":66,"d":"66.00"},200.39,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/evodine.html","C18H19NO5","Free Base","N/A","COC1=C(OCC(O)C(C)=C)C=CC2=C(OC)C3=C(OC=C3)N=C12",3.022,5,1,6]
["S9566","Bepridil hydrochloride","h5","L4000-16","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Bepridil hydrochloride(CERM 1978) is an anti-anginal drug classified as a calcium channel blocker. It also blocks multiple other ion channels, including sodium and potassium channels.",421.02,"74764-40-2",{"v":41,"d":"41.00"},97.38,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/bepridil-hydrochloride.html","C24H37ClN2O2","hydrochloride","CERM 1978","O.Cl.CC(C)COCC(CN(CC1=CC=CC=C1)C2=CC=CC=C2)N3CCCC3",5.439,1,0,10]
["S5856","Trifluoperazine","a6","L4000-16","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Trifluoperazine (NSC-17474, RP-7623, SKF-5019) is an FDA-approved antipsychotic drug for schizophrenia. It is an inhibitor of calmodulin (CaM) and Dopamine D2 receptor with an IC50 value of 1.2 nM for D2 receptor.",{"v":407.5,"d":"407.50"},"117-89-5","N/A","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","http://www.selleck.cn/products/trifluoperazine.html","C21H24F3N3S","Free Base","NSC-17474, RP-7623, SKF-5019","CN1CCN(CCCN2C3=C(SC4=C2C=C(C=C4)C(F)(F)F)C=CC=C3)CC1",4.975,0,0,5]
["S6579","RCGD423","b6","L4000-16","in 10mM DMSO","Interleukins","Transmembrane Transporters","RCGD-423 is a modulator of Glycoprotein 130 (gp130, IL6ST, IL6-beta, CD130) signalling that regulates cartilage growth and differentiation.",331.23,"108237-91-8",{"v":66,"d":"66.00"},199.26,"<1","N/A","http://www.selleck.cn/products/rcgd423.html","C15H11BrN2S","Free Base","N/A","BrC1=CC=C(NC2=NC(=CS2)C3=CC=CC=C3)C=C1",5.072,1,1,3]
["S6583","Apraclonidine HCl","c6","L4000-16","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Apraclonidine (Iopidine,ALO 2145) is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.",281.57,"73218-79-8",{"v":56,"d":"56.00"},198.88,{"v":19,"d":"19.00"},67.48,"http://www.selleck.cn/products/apraclonidine-hcl.html","C9H11Cl3N4","Hydrochloride","Iopidine HCl,ALO 2145","Cl.NC1=CC(=C(NC2=NCCN2)C(=C1)Cl)Cl",1.989,1,3,2]
["S6602","TB5","d6","L4000-16","in 10mM DMSO","MAO","Metabolism","TB5 is a potent and selective MAO-B inhibitor with Ki values of 110 and 1,450 nM for MAO-B and MAO-A, respectively.",336.25,"948841-07-4",{"v":67,"d":"67.00"},199.26,"<1","N/A","http://www.selleck.cn/products/tb5.html","C15H14BrNOS","Free Base","N/A","CN(C)C1=CC=C(\\C=C\\C(=O)C2=CC=C(Br)S2)C=C1",4.385,1,0,4]
["S6619","ABT 702 dihydrochloride","e6","L4000-16","in 10mM DMSO","Adenosine Kinase","Neuronal Signaling","ABT-702 is a novel, potent non-nucleoside Adenosine kinase inhibitor with an IC50 of 1.7 nM. It has oral activity in animal models of pain and inflammation.",536.25,"1188890-28-9",{"v":100,"d":"100.00"},186.48,"<1","N/A","http://www.selleck.cn/products/abt-702-dihydrochloride.html","C22H21BrCl2N6O","Dihydrochloride","N/A","Cl.Cl.NC1=C2C(=NC=N1)N=C(C=C2C3=CC(=CC=C3)Br)C4=CN=C(C=C4)N5CCOCC5",4.441,5,1,3]
["S6637","HC-067047","f6","L4000-16","in 10mM DMSO","TRP Channel","Transmembrane Transporters","HC-067047 is a selective TRPV4 channel antagonist with IC50 values of 48 nM,133 nM,and 17 nM for human, rat, and mouse TRPV4 orthologs,respectively.",471.51,"883031-03-6",{"v":94,"d":"94.00"},199.36,"<1","N/A","http://www.selleck.cn/products/hc-067047.html","C26H28F3N3O2","Free Base","N/A","CC1=C(C=C([N]1CCCN2CCOCC2)C3=CC=CC=C3)C(=O)NC4=CC=CC(=C4)C(F)(F)F",{"v":4.7,"d":"4.700"},2,1,8]
["S6638","AMG-333","g6","L4000-16","in 10mM DMSO","TRP Channel","Transmembrane Transporters","AMG-333 is a potent and highly selective antagonist of TRPM8 with IC50 values of 13 nM and 30 nM for human TRPM8 and rat TRPM8.",453.32,"1416799-28-4",{"v":91,"d":"91.00"},200.74,"<1","N/A","http://www.selleck.cn/products/amg-333.html","C20H12F5N3O4","Free Base","N/A","OC(=O)C1=CN=C(C=C1)C(=O)NC(C2=CC(=C(OC(F)(F)F)C=C2)F)C3=C(F)C=CC=N3",4.843,5,1,7]
["S6644","Radiprodil (RGH-896)","h6","L4000-16","in 10mM DMSO","NMDAR","Neuronal Signaling","Radiprodil (RGH-896) is a NR2B-selective NMDA receptor antagonist, initially developed for the treatment of neuropathic pain.",{"v":397.4,"d":"397.40"},"496054-87-6",{"v":79,"d":"79.00"},198.79,"<1","N/A","http://www.selleck.cn/products/radiprodil.html","C21H20FN3O4","Free Base","N/A","FC1=CC=C(CC2CCN(CC2)C(=O)C(=O)NC3=CC4=C(NC(=O)O4)C=C3)C=C1",2.883,4,2,4]
["S6646","Ciforadenant (CPI-444)","a7","L4000-16","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","Ciforadenant (CPI-444, V81444) is a potent and selective Adenosine A2A receptor antagonist. It binds to A2A receptors with a Ki of 3.54 nmol/L and demonstrates a greater than 50-fold selectivity for the A2A receptor over other adenosine receptor subtypes.",407.43,"1202402-40-1",{"v":81,"d":"81.00"},198.81,"<1","N/A","http://www.selleck.cn/products/cpi-444.html","C20H21N7O3","Free Base","V81444","CC1=CC=C(O1)C2=C3N=N[N](CC4=NC(=CC=C4)COC5CCOC5)C3=NC(=N2)N",1.769,8,1,6]
["S6717","TCS-OX2-29","b7","L4000-16","in 10mM DMSO","OX Receptor","GPCR & G Protein","TCX-OX2-29 is a OX2R antagonist (pKi = 7.5) that exhibits >250-fold selectivity for hOX2R compared with hOX1R (IC50s = 40 nM and >10,000 nM, respectively).",397.51,"372523-75-6",{"v":87,"d":"87.00"},218.86,"<1","N/A","http://www.selleck.cn/products/tcs-ox2-29.html","C23H31N3O3","Free Base","N/A","COC1=CC2=C(CN(CC2)C(=O)C(NCC3=CC=NC=C3)C(C)(C)C)C=C1OC",2.709,4,1,7]
["S6726","MK1064","c7","L4000-16","in 10mM DMSO","OX Receptor","GPCR & G Protein","MK1064 is a selective orexin 2 receptor antagonist (2-SORA) with an IC50 of 18 nM.",{"v":461.9,"d":"461.90"},"1207253-08-4",{"v":92,"d":"92.00"},199.18,"<1","N/A","http://www.selleck.cn/products/mk1064.html","C24H20ClN5O3","Free Base","N/A","COC1=C(OC)N=C(CNC(=O)C2=CC(=CN=C2C3=NC=CC=C3)C4=CC(=CN=C4)Cl)C=C1",3.298,7,1,7]
["S6733","Edonerpic maleate","d7","L4000-16","in 10mM DMSO","Beta Amyloid","Neuronal Signaling","Edonerpic maleate (T-817) is a novel neurotrophic agent which can inhibit amyloid-β peptides (Aβ).",407.48,"519187-97-4",{"v":81,"d":"81.00"},198.78,{"v":81,"d":"81.00"},198.78,"http://www.selleck.cn/products/edonerpic-maleate.html","C20H25NO6S","Free Base","T-817 maleate","OC1CN(CCCOCCC2=CC3=C(SC=C3)C=C2)C1.OC(=O)\\C=C/C(O)=O",{"v":-0.67,"d":"-0.670"},3,1,9]
["S6735","JD-5037","e7","L4000-16","in 10mM DMSO","Cannabinoid Receptor","GPCR & G Protein","JD-5037 is a peripherally restricted (PR) cannabinoid-1 receptor blocker with an IC50 value of 2 nM for CB1 receptor and > 1000 nM for CB2 receptor.",572.51,"1392116-14-1",{"v":100,"d":"100.00"},174.67,"<1","N/A","http://www.selleck.cn/products/id-5037.html","C27H27Cl2N5O3S","Free Base","N/A","CC(C)C(N=C(N[S](=O)(=O)C1=CC=C(Cl)C=C1)N2CC(C3=CC=CC=C3)C(=N2)C4=CC=C(Cl)C=C4)C(N)=O",5.552,5,2,9]
["S6746","APD668","f7","L4000-16","in 10mM DMSO","GPR","Endocrinology & Hormones","APD668 (JNJ28630368) is a potent GPR119 agonist with EC50s of 2.7 and 33 nM for human and rat forms, respectively.",477.51,"832714-46-2",{"v":96,"d":"96.00"},201.04,"<1","N/A","http://www.selleck.cn/products/apd668.html","C21H24FN5O5S","Free Base","JNJ28630368","CC(C)OC(=O)N1CCC(CC1)OC2=NC=NC3=C2C=N[N]3C4=CC=C(C=C4F)[S](C)(=O)=O",{"v":2.67,"d":"2.670"},8,0,6]
["S8901","Taletrectinib (DS-6051b)","g7","L4000-16","in 10mM DMSO","ROS1,Trk receptor","Immunology & Inflammation","Taletrectinib (DS-6051b, AB-106) is a new-generation selective ROS1/NTRK inhibitor with ic50 of 0.207 nM,0.622 nM,2.28 nM and 0.980 nM for ROS1,NTRK1,NTRK2 and NTRK3,respectively.",551.61,"1505515-69-4",{"v":50,"d":"50.00"},90.64,"<1","N/A","http://www.selleck.cn/products/ds-6051b.html","C29H34FN5O5","Free Base","AB-106","CC(N)COC1=CC=C(C=C1)C2=CN=C3C=CC(=N[N]23)NC(C)C4=CC(=CC=C4)F.OC(=O)CCCCC(O)=O",{"v":2.17,"d":"2.170"},5,2,12]
["S9050","Boldine","h7","L4000-16","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Boldine, isolated from Peumus boldus, has alpha-adrenergic antagonist activities in vascular tissue with anti-oxidant, hepatoprotective, cytoprotective, antipyretic and anti-inflammatory effects.",327.37,"476-70-0",{"v":10,"d":"10.00"},30.55,"N/A","N/A","https://www.selleckchem.com/products/boldine.html","C19H21NO4","free base","1, 10-Dimethoxy-2, 9-dihydroxyaporphine; ex Peumus boldus","COC1=C(O)C=C2CC3N(C)CCC4=CC(=C(OC)C(=C34)C2=C1)O",3.083,2,2,2]
["S9086","Dihydrocapsaicin","a8","L4000-16","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Dihydrocapsaicin (6,7-Dihydrocapsaicin, 8-Methyl-N-vanillylnonanamide, CCRIS1589), found in pepper (C. annuum), is a potential nutriceutical.DHC is a selective TRPV1 agonist.",307.43,"19408-84-5",{"v":10,"d":"10.00"},32.53,"N/A","N/A","https://www.selleckchem.com/products/dihydrocapsaicin.html","C18H29NO3","free base","6,7-Dihydrocapsaicin, 8-Methyl-N-vanillylnonanamide, CCRIS1589","COC1=C(O)C=CC(=C1)CNC(=O)CCCCCCC(C)C",4.354,2,2,10]
["S9285","Fargesin","b8","L4000-16","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Fargesin is a neolignan isolated from Magnolia plants. It is a potential β1AR antagonist through cAMP/PKA pathway.",{"v":370.4,"d":"370.40"},"31008-19-2",{"v":36,"d":"36.00"},97.19,"N/A","N/A","https://www.selleckchem.com/products/fargesin.html","C21H22O6","free base","N/A","COC1=CC=C(C=C1OC)C2OCC3C2COC3C4=CC5=C(OCO5)C=C4",2.436,6,0,4]
["S9138","Picfeltarraenin IA","c8","L4000-16","in 10mM DMSO","AChR,Complement System","Neuronal Signaling","Picfeltarraenin IA is an AChE inhibitior, and an potential PI3K and EGFR inhibitor. It also acts as an inhibitor on both the classical and alternative pathways of the complement system.",762.92,"97230-47-2",{"v":100,"d":"100.00"},131.07,"N/A","N/A","https://www.selleckchem.com/products/picfeltarraenin-ia.html","C41H62O13","free base","N/A","CC(C)C1=CC(=O)C(C)(O1)C2C(O)CC3(C)C4CC=C5C(CCC(OC6OCC(O)C(O)C6OC7OC(C)C(O)C(O)C7O)C5(C)C)C4(C)C(=O)CC23C",{"v":1.72,"d":"1.720"},7,6,6]
["S2272","Indoprofen","d8","L4000-16","in 10mM DMSO","COX,Others,PDPK1","PI3K/Akt/mTOR","Indoprofen is a nonsteroidal anti-inflammatory drug (NSAID) and cyclooxygenase (COX) inhibitor. Indoprofen prevents muscle wasting in aged mice through activation of PDK1/AKT pathway.Indoprofen selectively increases SMN2-luciferase reporter protein and endogenous SMN protein.",281.31,"31842-01-0",{"v":52,"d":"52.00"},184.85,"<1","N/A","http://www.selleck.cn/products/indoprofen.html","C17H15NO3","Free Base","N/A","CC(C(O)=O)C1=CC=C(C=C1)N2CC3=C(C=CC=C3)C2=O",2.701,2,0,3]
["S2418","Frentizole","e8","L4000-16","in 10mM DMSO","Beta Amyloid","Neuronal Signaling","Frentizole (Frentizol) is a novel inhibitor of amyloid beta peptide (Abeta) binding alcohol dehydrogenase (ABAD) interaction with IC50 of 200 μM. Frentizole is a nontoxic antiviral and immunosuppressive agent used clinically in rheumatoid arthritis and systemic lupus erythematosus.",299.35,"26130-02-9",{"v":60,"d":"60.00"},200.43,"<1","N/A","http://www.selleck.cn/products/frentizole.html","C15H13N3O2S","Free Base","Frentizol","COC1=CC=C2N=C(NC(=O)NC3=CC=CC=C3)SC2=C1",3.132,3,2,3]
["S2419","Eprobemide","f8","L4000-16","in 10mM DMSO","MAO","Metabolism","Eprobemide is a reversible monoamine oxidase A (MAO-A) inhibitor. Eprobemide acts as an antidepressant in Russia.",282.77,"87940-60-1",{"v":57,"d":"57.00"},201.58,"<1","N/A","http://www.selleck.cn/products/eprobemide.html","C14H19ClN2O2","Free Base","Befol, LIS 630","ClC1=CC=C(C=C1)C(=O)NCCCN2CCOCC2",1.591,2,1,5]
["S2421","PF-04457845","g8","L4000-16","in 10mM DMSO","FAAH","Metabolism","PF-04457845 (PF-4457845) is a potent, favorable selective inhibitor of Fatty acid amide hydrolase (FAAH) with IC50 of 7.2 nM and 7.4 nM for hFAAH and rFAAH, respectively. PF-04457845 covalently modifies the active-site serine nucleophile of FAAH with exquisite selectivity relative to other members of the serine hydrolase superfamily.",455.43,"1020315-31-4",{"v":91,"d":"91.00"},199.81,"<1","N/A","https://www.selleckchem.com/products/pf-04457845.html","C23H20F3N5O2","Free Base","PF-4457845","FC(F)(F)C1=CN=C(OC2=CC(=CC=C2)C=C3CCN(CC3)C(=O)NC4=NN=CC=C4)C=C1",4.371,5,1,5]
["S2434","IDRA-21","h8","L4000-16","in 10mM DMSO","GluR","Neuronal Signaling","IDRA-21 is a partial allosteric modulator of AMPA receptor desensitization. IDRA-21 is a potent cognition-enhancing drug virtually devoid of neurotoxic liability.",232.69,"22503-72-6",{"v":47,"d":"47.00"},201.99,"<1","N/A","http://www.selleck.cn/products/idra-21.html","C8H9ClN2O2S","Free Base","N/A","CC1NC2=CC=C(Cl)C=C2[S](=O)(=O)N1",1.193,2,2,0]
["S2436","Pranidipine","a9","L4000-16","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Pranidipine (Acalas, OPC 13340) is a new 1,4-dihydropyridine calcium channel blocker. Pranidipine can enhance cyclic GMP-independent nitric oxide-induced relaxation of the rat aorta.",448.47,"99522-79-9",{"v":90,"d":"90.00"},200.68,"<1","N/A","http://www.selleck.cn/products/pranidipine.html","C25H24N2O6","Free Base","Acalas, OPC 13340","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OC\\C=C\\C3=CC=CC=C3)C",3.817,4,1,9]
["S2644","Lerisetron","b9","L4000-16","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Lerisetron (F 0930, F 0930RS) is a 5-HT3 receptor antagonist with IC50 of 0.81μM.",292.38,"143257-98-1",{"v":58,"d":"58.00"},198.37,"<1","N/A","http://www.selleck.cn/products/lerisetron.html","C18H20N4","Free Base","F 0930, F 0930RS","C1CN(CCN1)C2=NC3=C(C=CC=C3)[N]2CC4=CC=CC=C4",{"v":3.26,"d":"3.260"},1,1,3]
["S2645","SIB 1757","c9","L4000-16","in 10mM DMSO","GluR","Neuronal Signaling","SIB 1757 is a highly selective, noncompetitive antagonist of metabotropic glutamate receptor type 5 (mGluR5) with IC50 of 0.4 μM at hmGluR5 compared with >30 µM at hmGluR1b, hmGluR2, hmGluR4, hmGluR6, hmGluR7 and hmGluR8.",213.24,"31993-01-8",{"v":22,"d":"22.00"},103.17,"<1","N/A","http://www.selleck.cn/products/sib-1757.html","C12H11N3O","Free Base","N/A","CC1=NC(=C(O)C=C1)N=NC2=CC=CC=C2",3.628,3,1,2]
["S6634","SAR7334","d9","L4000-16","in 10mM DMSO","TRP Channel","Transmembrane Transporters","SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels.SAR7334 blocks TRPC6 currents with an IC50 of 7.9 nM in patch-clamp experiment.",367.87,"1333210-07-3",{"v":74,"d":"74.00"},201.16,"<1","N/A","http://www.selleck.cn/products/sar7334.html","C21H22ClN3O","Free Base","N/A","NC1CCCN(C1)C2CC3=C(C=CC=C3)C2OC4=CC=C(C=C4Cl)C#N",3.871,1,1,3]
["S6649","E7046 (ER-886406)","e9","L4000-16","in 10mM DMSO","Prostaglandin Receptor","GPCR & G Protein","E7046 (ER-886406, Palupiprant, AN0025) is a selective inhibitor of the prostaglandin E2 (PGE2) receptor EP4 with IC50 of 13.5 nM and Ki of 23.14 nM.",483.39,"1369489-71-3",{"v":100,"d":"100.00"},206.87,{"v":-1,"d":"-1.00"},"N/A","http://www.selleck.cn/products/e7046.html","C22H18F5N3O4","Free Base","Palupiprant, AN0025","CC(NC(=O)C1=C(OC2=CC=CC(=C2)C(F)(F)F)[N](C)N=C1C(F)F)C3=CC=C(C=C3)C(O)=O",4.787,4,1,8]
["S6657","2-Aminoethyl Diphenylborinate (2-APB)","f9","L4000-16","in 10mM DMSO","Calcium Channel,TRP Channel","Transmembrane Transporters","2-Aminoethyl Diphenylborinate (2-APB) is an IP3 receptor inhibitor and regulate IP3-induced calcium release.2-APB also inhibits the SOC channel activity and activates TRP channel at higher concentrations.",225.09,"524-95-8",{"v":45,"d":"45.00"},199.92,"<1","N/A","http://www.selleck.cn/products/2-aminoethyl-diphenylborinate.html","C14H16BNO","Free Base","N/A","NCCOB(C1=CC=CC=C1)C2=CC=CC=C2",3.656,1,1,5]
["S6659","Rimegepant (BMS-927711)","g9","L4000-16","in 10mM DMSO","CGRP Receptor","GPCR & G Protein","Rimegepant (BMS-927711, BHV-3000) is a potent, selective, competitive human calcitonin gene-related peptide (CGRP) receptor antagonist with ki of 0.027 nM.",534.56,"1289023-67-1",{"v":100,"d":"100.00"},187.07,"<1","N/A","http://www.selleck.cn/products/bms-927711.html","C28H28F2N6O3","Free Base","BHV-3000","NC1C(CCC(OC(=O)N2CCC(CC2)N3C(=O)NC4=NC=CC=C34)C5=NC=CC=C15)C6=CC=CC(=C6F)F",2.898,5,2,4]
["S6665","Sparsentan (PS-433540, RE-021)","h9","L4000-16","in 10mM DMSO","Angiotensin Receptor,Endothelin Receptor","GPCR & G Protein","Sparsentan (PS-433540, RE-021, DARA) is a dual endothelin type A receptor(ETA) and angiotensin II type 1 receptor antagonist.",592.75,"254740-64-2",{"v":100,"d":"100.00"},168.71,"<1","N/A","http://www.selleck.cn/products/sparsentan.html","C32H40N4O5S","Free Base","DARA","CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C(=C3)COCC)C4=CC=CC=C4[S](=O)(=O)NC5=NOC(=C5C)C",5.728,7,1,12]
["S6676","Ebselen","a10","L4000-16","in 10mM DMSO","COVID-19,HIV","Microbiology","Ebselen (DR 3305, SPI-1005, PZ-51, CCG-39161) is a small-molecule capsid inhibitor of HIV-1 Replication with IC50 of 46.1 nM in TR-FRET assay.",274.18,"60940-34-3",{"v":55,"d":"55.00"},{"v":200.6,"d":"200.60"},"<1","N/A","http://www.selleck.cn/products/ebselen.html","C13H9NOSe","Free Base","DR 3305, SPI-1005, PZ-51, CCG-39161","O=C1N([Se]C2=C1C=CC=C2)C3=CC=CC=C3",3.227,1,0,1]
["S9117","(20S)Ginsenoside Rg2","b10","L4000-16","in 10mM DMSO","Others","Others","(20S)Ginsenoside Rg2, a constituent existing in red ginseng, has been reported to exert strong inhibitory action on various cancer cells.",785.01,"52286-74-5",{"v":100,"d":"100.00"},127.39,"<1","N/A","http://www.selleck.cn/products/20s-ginsenoside-rg2.html","C42H72O13","Free Base","N/A","CC1OC(OC2C(O)C(O)C(CO)OC2OC3CC4(C)C(CC(O)C5C(CCC45C)C(C)(O)CCC=C(C)C)C6(C)CCC(O)C(C)(C)C36)C(O)C(O)C1O",2.014,4,8,9]
["S9145","Solamargine","c10","L4000-16","in 10mM DMSO","P-gp","Neuronal Signaling","Solamargine, a bioactive steroidal alkaloid isolated from Solanum aculeastrum, induces potent, non-selective cytotoxicity and P-gp inhibition.",868.06,"20311-51-7",{"v":100,"d":"100.00"},{"v":115.2,"d":"115.20"},"<1","N/A","http://www.selleck.cn/products/solamargine.html","C45H73NO15","Free Base","N/A","CC1CCC2(NC1)OC3CC4C5CC=C6CC(CCC6(C)C5CCC4(C)C3C2C)OC7OC(CO)C(OC8OC(C)C(O)C(O)C8O)C(O)C7OC9OC(C)C(O)C(O)C9O",0.903,7,9,7]
["S9290","Linarin","d10","L4000-16","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Linarin (Acaciin, Buddleoside, Acacetin-7-O-rutinoside), a natural flavonoid cpompound, has pharmacological effects, including anti-inflammatory, neuro-protective, cardioprotective and antioxidative effects.",592.55,"480-36-4",{"v":100,"d":"100.00"},168.76,"<1","N/A","http://www.selleck.cn/products/linarin.html","C28H32O14","Free Base","Acaciin, Buddleoside, Acacetin-7-O-rutinoside","COC1=CC=C(C=C1)C2=CC(=O)C3=C(O)C=C(OC4OC(COC5OC(C)C(O)C(O)C5O)C(O)C(O)C4O)C=C3O2",-0.153,7,7,7]
["S0160","Toloxatone (MD69276)","e10","L4000-16","in 10mM DMSO","MAO","Metabolism","Toloxatone (MD69276, Humoryl, Perenum, Umoril) is a reversible inhibitor of monoamine oxidase A (MAO-A) with IC50 of  0.93 µM. Toloxatone is an antidepressant agent.",207.23,"29218-27-7",{"v":41,"d":"41.00"},197.85,"˂1","N/A","http://www.selleckchem.com/products/md69276.html","C11H13NO3","Free Base","Humoryl, Perenum, Umoril","CC1=CC=CC(=C1)N2CC(CO)OC2=O",1.593,2,1,2]
["S0222","Lvguidingan","f10","L4000-16","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Lvguidingan (Anticonvulsant 7903, 3,4-dichlorophenyl propenylisobutylamide) is an anticonvulsant/antiepileptic agent. Lvguidingan (Anticonvulsant 7903) is found to be able to increase the concentration of 5-HT and 5-HIAA in mice brain.",272.17,"82351-05-1",{"v":54,"d":"54.00"},198.41,"˂1","N/A","http://www.selleckchem.com/products/lvguidingan.html","C13H15Cl2NO","Free Base","Anticonvulsant 7903, 3,4-dichlorophenyl propenylisobutylamide","CCC(C)NC(=O)\\C=C\\C1=CC(=C(Cl)C=C1)Cl",4.084,1,1,4]
["S0295","Anavex 2-73 HCl","g10","L4000-16","in 10mM DMSO","Sigma Receptor","GPCR & G Protein","Anavex 2-73 (Blarcamesine, AVex-73, AE-37), an aminotetrahydrofuran derivative, is a mixed muscarinic and sigma-1/σ1 Receptor agonist with IC50 of 0.86 μM.",317.85,"195615-84-0",{"v":64,"d":"64.00"},201.35,{"v":64,"d":"64.00"},201.35,"http://www.selleckchem.com/products/anavex-2-73.html","C19H24ClNO","Hydrochloride","Blarcamesine hydrochloride, AVex-73 hydrochloride, AE-37 hydrochloride","Cl.CN(C)CC1CCOC1(C2=CC=CC=C2)C3=CC=CC=C3",3.722,1,0,4]
["S0779","Pirenperone","h10","L4000-16","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Pirenperone (R-47456, R-50656), a quinazoline derivative, is a selective antagonist of SR-2A (5-HT2 serotonin receptor) when employed in low doses. Pirenperone behaves like a typical neuroleptic when used in higher doses (greater than 0.1 mg/kg).",393.45,"75444-65-4",{"v":17,"d":"17.00"},43.21,"<1","N/A","http://www.selleckchem.com/products/pirenperone.html","C23H24FN3O2","Free Base","R-47456, R-50656","CC1=C(CCN2CCC(CC2)C(=O)C3=CC=C(F)C=C3)C(=O)N4C=CC=CC4=N1",2.711,3,0,5]
["S2121","Licofelone (ML3000)","a11","L4000-16","in 10mM DMSO","COX","Neuronal Signaling","Licofelone (ML3000, Compound 3e) is a dual inhibitor of COX and 5-lipoxygenase (5-LOX) with IC50 of 0.21 μM and 0.18 μM, respectively. Licofelone induces apoptosis, and decreases the production of proinflammatory leukotrienes and prostaglandins. Licofelone is considered as a treatment for osteoarthritis.",379.88,"156897-06-2",{"v":19,"d":"19.00"},50.02,"<1","N/A","http://www.selleckchem.com/products/licofelone.html","C23H22ClNO2","Free Base","ML3000","CC1(C)C[N]2C(=C(C3=CC=C(Cl)C=C3)C(=C2C1)C4=CC=CC=C4)CC(O)=O",{"v":5.78,"d":"5.780"},1,0,4]
["S2578","1-Phenylbiguanide","b11","L4000-16","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","1-Phenylbiguanide (Phenylbiguanide, PBG, N-Phenylbiguanide) is a 5-hydroxytryptamine3 (5-HT3) receptor agonist with EC50 of 3.0 μM.",177.21,"102-02-3",{"v":35,"d":"35.00"},197.51,{"v":35,"d":"35.00"},197.51,"http://www.selleckchem.com/products/1-phenylbiguanide.html","C8H11N5","Free Base","Phenylbiguanide, PBG, N-Phenylbiguanide","NC(=N)NC(=N)NC1=CC=CC=C1",0.629,0,3,4]
["S2595","FK-3311","c11","L4000-16","in 10mM DMSO","COX","Immunology & Inflammation","FK-3311 (COX-2 Inhibitor V) is a selective, cell-permeable and orally available inhibitor of cyclooxygenase-2 (COX-2) with antiinflammatory. FK-3311 has protective effects against hepatic warm ischemia-reperfusion injury by marked inhibition of TxA2.",341.33,"116686-15-8",{"v":68,"d":"68.00"},199.22,"<1","N/A","http://www.selleckchem.com/products/fk-3311.html","C15H13F2NO4S","Free Base","COX-2 Inhibitor V","CC(=O)C1=CC=C(N[S](C)(=O)=O)C(=C1)OC2=CC=C(F)C=C2F",2.452,4,1,5]
["S2642","1-Naphthyl PP1(1-NA-PP1)","d11","L4000-16","in 10mM DMSO","Bcr-Abl,CaMK,CDK,PKD,Src","Angiogenesis","1-Naphthyl PP1(1-NA-PP 1) is a highly selective and potent pan-PKD inhibitor with IC50 of  154.6 nM,133.4 nM and 109.4 nM for PKD1, PKD2 and PKD3, respectively. 1-Naphthyl PP1 is a selective inhibitor of Src family kinases (v-Src, c-Fyn) and the tyrosine kinase c-Abl with IC50 of 1.0 μM, 0.6 μM, 0.6 μM, 18 μM and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II, respectively.",317.39,"221243-82-9",{"v":9,"d":"9.00"},28.36,"<1","N/A","http://www.selleckchem.com/products/1-na-pp1.html","C19H19N5","Free Base","N/A","CC(C)(C)[N]1N=C(C2=CC=CC3=C2C=CC=C3)C4=C1N=CN=C4N",3.679,3,1,2]
["S2646","VU0238429","e11","L4000-16","in 10mM DMSO","AChR","Neuronal Signaling","VU0238429 (M5 PAM) is the first positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5/M5) with EC50 of 1.16 μM at M5 and both > 30 μM at M1 and M3. VU0238429 shows no potentiator activity at M2 or M4.",351.28,"1160247-92-6",{"v":70,"d":"70.00"},199.27,"<1","N/A","http://www.selleckchem.com/products/vu0238429.html","C17H12F3NO4","Free Base","M5 PAM","COC1=CC=C(CN2C(=O)C(=O)C3=C2C=CC(=C3)OC(F)(F)F)C=C1",4.563,4,0,5]
["S2649","SB 200646","f11","L4000-16","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","SB 200646 (SB 200646A) is a potent, selective and oral-active antagonist of 5-HT2B/2C over 5-HT2A receptor with 50 fold selectivity. The pKi for rat 5-HT2C receptor, rat 5-HT2B receptor and rat 5-HT2A receptor are 6.9, 7.5 and 5.2, respectively. SB 200646 has electrophysiological and anxiolytic properties in vivo.",{"v":266.3,"d":"266.30"},"143797-63-1",{"v":53,"d":"53.00"},199.02,"˂1","N/A","http://www.selleckchem.com/products/sb-200646.html","C15H14N4O","Free Base","SB 200646A","C[N]1C=CC2=C1C=CC(=C2)NC(=O)NC3=CC=CN=C3",1.871,2,2,2]
["S2650","RN-1734","g11","L4000-16","in 10mM DMSO","TRP Channel","Transmembrane Transporters","RN-1734 (TRPV4 Antagonist I) is a selective transient receptor potential vanilloid 4 (TRPV4) antagonist with IC50 of 2.3 μM, 5.9 μM and 3.2 μM for hTRPV4, mTRPV4 and rTRPV4, respectively. RN-1734 alleviates demyelination and inhibits glial activation and the production of tumor necrosis factor α (TNF-α) and interleukin 1β (IL-1β) without altering the number of olig2-positive cells.",353.31,"946387-07-1",{"v":71,"d":"71.00"},200.96,"<1","N/A","http://www.selleckchem.com/products/rn-1734.html","C14H22Cl2N2O2S","Free Base","TRPV4 Antagonist I","CC(C)NCCN(C(C)C)[S](=O)(=O)C1=CC=C(Cl)C=C1Cl",3.331,2,1,7]
["S6615","ATB 346","h11","L4000-16","in 10mM DMSO","Apoptosis related,COX,Others","Immunology & Inflammation","ATB 346, a novel hydrogen sulphide-releasing derivative of naproxen with remarkably reduced toxicity, inhibits COX activity. ATB 346 is an anti-inflammatory agent that induces apoptosis of human melanoma cells.",365.45,"1226895-20-0",{"v":73,"d":"73.00"},199.75,"<1","N/A","http://www.selleckchem.com/products/atb-346.html","C21H19NO3S","Free Base","N/A","COC1=CC2=CC=C(C=C2C=C1)C(C)C(=O)OC3=CC=C(C=C3)C(N)=S",4.521,3,1,6]
["S6685","Mavacoxib","a2","L4000-17","in 10mM DMSO","COX","Immunology & Inflammation","Mavacoxib (Trocoxil) is a selective, long-acting cyclooxygenase-2 (COX-2) inhibitor. Mavacoxib is a novel nonsteroidal anti-inflammatory drug (NSAID).",385.34,"170569-88-7",{"v":77,"d":"77.00"},199.82,"<1","N/A","http://www.selleckchem.com/products/mavacoxib.html","C16H11F4N3O2S","Free Base","Trocoxil","N[S](=O)(=O)C1=CC=C(C=C1)[N]2N=C(C=C2C3=CC=C(F)C=C3)C(F)(F)F",4.147,3,1,4]
["S6686","SC-560","b2","L4000-17","in 10mM DMSO","COX","Immunology & Inflammation","SC-560 is a highly selective COX-1 inhibitor with IC50 of 9 nM, compared with the IC50 of 6.3 μM for COX-2, nearly 1,000-fold higher than with COX-1.",352.74,"188817-13-2",{"v":70,"d":"70.00"},198.45,"<1","N/A","http://www.selleckchem.com/products/sc-560.html","C17H12ClF3N2O","Free Base","N/A","COC1=CC=C(C=C1)[N]2N=C(C=C2C3=CC=C(Cl)C=C3)C(F)(F)F",5.885,2,0,4]
["S6780","TFAP","c2","L4000-17","in 10mM DMSO","COX","Immunology & Inflammation","TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective and cell-permeable cyclooxygenase-1 (COX-1) inhibitor with IC50 of 0.8 μM.",281.23,"1011244-68-0",{"v":56,"d":"56.00"},199.13,"<1","N/A","http://www.selleckchem.com/products/tfap.html","C13H10F3N3O","Free Base","N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide","NC1=CN=C(NC(=O)C2=CC=C(C=C2)C(F)(F)F)C=C1",2.198,2,2,3]
["S6787","KN-93","d2","L4000-17","in 10mM DMSO","CaMK","Neuronal Signaling","KN-93 is a cell-permeable, reversible and competitive inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMK-II) with Ki of 2.58 μM at rabbit myocardial CaM kinase activity.",501.04,"139298-40-1",{"v":100,"d":"100.00"},199.58,"<1","N/A","http://www.selleckchem.com/products/kn-93.html","C26H29ClN2O4S","Free Base","N/A","COC1=CC=C(C=C1)[S](=O)(=O)N(CCO)C2=CC=CC=C2CN(C)C\\C=C\\C3=CC=C(Cl)C=C3",4.757,3,1,11]
["S6795","VU0357017 Hydrochloride","e2","L4000-17","in 10mM DMSO","AChR","Neuronal Signaling","VU0357017 hydrochloride (CID-25010775) is a potent, highly selective and CNS-penetrant agonist of M1 which is a subtype of muscarinic acetylcholine receptors (mAChRs). VU0357017 hydrochloride appears to act at an allosteric site to activate the receptor with EC50 of 477 nM and Ki of 9.91 μM.",369.89,"1135242-13-5",{"v":38,"d":"38.00"},102.73,{"v":10,"d":"10.00"},27.04,"http://www.selleckchem.com/products/vu0357017-hydrochloride.html","C18H28ClN3O3","Hydrochloride","CID-25010775","Cl.CCOC(=O)N1CCC(CC1)NCCNC(=O)C2=CC=CC=C2C",1.871,3,2,7]
["S6804","CX546","f2","L4000-17","in 10mM DMSO","GluR","Neuronal Signaling","CX546, a prototypical ampakine agent, is a selective positive AMPA receptor modulator.",247.29,"215923-54-9",{"v":49,"d":"49.00"},198.15,"<1","N/A","http://www.selleckchem.com/products/cx546.html","C14H17NO3","Free Base","N/A","O=C(N1CCCCC1)C2=CC=C3OCCOC3=C2",1.947,3,0,1]
["S6815","CDN1163","g2","L4000-17","in 10mM DMSO","ATPase","Transmembrane Transporters","CDN1163 is a small molecular allosteric activator of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) that improves Ca2+ homeostasis.",320.39,"892711-75-0",{"v":64,"d":"64.00"},199.76,"<1","N/A","http://www.selleckchem.com/products/cdn1163.html","C20H20N2O2","Free Base","N/A","CC(C)OC1=CC=C(C=C1)C(=O)NC2=CC=CC3=CC=C(C)N=C23",3.793,3,1,4]
["S6838","BCTC","h2","L4000-17","in 10mM DMSO","TRP Channel","Transmembrane Transporters","BCTC is an orally effective and highly potent vanilloid receptor 1 (VR1/TRPV1) antagonist. BCTC inhibits capsaicin-induced and acid-induced activation of rat VR1 with IC50 of 35 nM and 6.0 nM, respectivley. BCTC exhibits anti-tumor activity.",372.89,"393514-24-4",{"v":74,"d":"74.00"},198.45,"˂1","N/A","http://www.selleckchem.com/products/bctc.html","C20H25ClN4O","Free Base","N/A","CC(C)(C)C1=CC=C(NC(=O)N2CCN(CC2)C3=NC=CC=C3Cl)C=C1",4.234,2,1,3]
["S8933","ONO-7475","a3","L4000-17","in 10mM DMSO","Axl,Mertk","Protein Tyrosine Kinase","ONO-7475 is a potent, selective, and orally active novel inhibitor of Anexelekto(Axl)/MER tyrosine kinase with IC50 of 0.7 nM and 1.0 nM for AXL and MER, respectively. ONO-7475 suppresses the emergence and maintenance of tolerant cells to the initial EGFR-TKIs, osimertinib or dacomitinib, in AXL-overexpressing EGFR-mutated NSCLC cells. ONO-7475 arrests growth and kills FMS-like tyrosine kinase 3-internal tandem duplication mutant acute myeloid leukemia cells.",562.57,"1646839-59-9",{"v":100,"d":"100.00"},177.76,"<1","N/A","http://www.selleckchem.com/products/ono-7475.html","C32H26N4O6","Free Base","N/A","COC1=CC2=C(C=C1OC)C(=CC=N2)OC3=CN=C(NC(=O)C4=CC5=C(CCCC5=O)N(C4=O)C6=CC=CC=C6)C=C3",3.872,8,1,7]
["S0016","SN-6","b3","L4000-17","in 10mM DMSO","AChR,Calcium Channel,NCX,Sodium Channel","Transmembrane Transporters","SN-6 is a selective Na+/Ca2+ exchanger (NCX) inhibitor. SN-6 inhibits NCX1, NCX2, and NCX3 with IC50 of 2.9 μM, 16 μM and 8.6 μM, respectively. SN-6 abolishes acetylcholine (ACh)-induced vasodilation.",402.46,"415697-08-4",{"v":80,"d":"80.00"},198.78,"<1","N/A","http://www.selleckchem.com/products/sn-6.html","C20H22N2O5S","free base","N/A","CCOC(=O)C1CSC(CC2=CC=C(OCC3=CC=C(C=C3)[N+]([O-])=O)C=C2)N1",3.715,3,1,9]
["S0116","Piperoxan hydrochloride","c3","L4000-17","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Piperoxan hydrochloride (Benodaine, Fourneau 933, F933, DL-Piperoxan) is an antagonist of α2 (alpha 2) adrenoceptor.",269.77,"135-87-5",{"v":54,"d":"54.00"},200.17,{"v":54,"d":"54.00"},200.17,"http://www.selleckchem.com/products/piperoxan-hydrochloride.html","C14H20ClNO2","hydrochloride","Benodaine, Fourneau 933, F933, DL-Piperoxan","Cl.C1CCN(CC1)CC2COC3=CC=CC=C3O2",3.082,2,0,2]
["S0174","TRPM8 antagonist 2","d3","L4000-17","in 10mM DMSO","TRP Channel","Transmembrane Transporters","TRPM8 antagonist 2 (TRPM8 Antagonist) is a potent and selective antagonist of TRPM8 with IC50 of 0.2 nM that can be used for the pharmacological treatment of neuropathic pain syndromes.",{"v":398.5,"d":"398.50"},"259674-19-6",{"v":80,"d":"80.00"},200.75,"<1","N/A","http://www.selleckchem.com/products/trpm8-antagonist-2.html","C26H26N2O2","free base","TRPM8 Antagonist","COC(=O)C(CC1=C[NH]C2=CC=CC=C12)N(CC3=CC=CC=C3)CC4=CC=CC=C4",5.527,2,1,9]
["S0191","BD1063 2HCL","e3","L4000-17","in 10mM DMSO","Sigma Receptor","GPCR & G Protein","BD1063 2HCL (BD1063 dihydrochloride) is a potent and selective sigma-1 receptor (σ1R) antagonist with Ki of 4.43 nM.",346.12,"206996-13-6",{"v":10,"d":"10.00"},28.89,{"v":69,"d":"69.00"},199.35,"http://www.selleckchem.com/products/bd1063-2hcl.html","C13H20Cl4N2","2HCL","BD1063 dihydrochloride","Cl.Cl.CN1CCN(CC1)CCC2=CC=C(Cl)C(=C2)Cl",4.274,0,0,3]
["S0225","IMR-1A","f3","L4000-17","in 10mM DMSO","Notch","Neuronal Signaling","IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.",325.36,"331862-41-0",{"v":6,"d":"6.00"},18.44,"<1","N/A","http://www.selleckchem.com/products/imr-1a.html","C13H11NO5S2","free base","N/A","COC1=CC(=CC=C1OCC(O)=O)\\C=C/2SC(=S)NC2=O",{"v":2.29,"d":"2.290"},4,1,5]
["S0297","UCPH-101","g3","L4000-17","in 10mM DMSO","EAAT","Transmembrane Transporters","UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with IC50 of 0.66 μM at EAAT1-HEK293 cells in the [3H]-D-Asp uptake assay.",422.48,"1118460-77-7",{"v":84,"d":"84.00"},198.83,"<1","N/A","http://www.selleckchem.com/products/ucph-101.html","C27H22N2O3","free base","N/A","COC1=CC=C(C=C1)C2C(=C(N)OC3=C2C(=O)CC(C3)C4=CC=CC5=CC=CC=C45)C#N",4.028,3,1,3]
["S0303","CGP52432","h3","L4000-17","in 10mM DMSO","GABA Receptor","Neuronal Signaling","CGP52432 is a potent and selective antagonist of GABAB autoreceptor with IC50 of 0.085 μM.",384.24,"139667-74-6",{"v":5,"d":"5.00"},13.01,{"v":2.5,"d":"2.50"},6.51,"http://www.selleckchem.com/products/cgp52432.html","C15H24Cl2NO4P","free base","N/A","CCOC(OCC)[P](O)(=O)CCCNCC1=CC=C(Cl)C(=C1)Cl",3.397,3,1,11]
["S0305","RO1138452","a4","L4000-17","in 10mM DMSO","Prostaglandin Receptor","Immunology & Inflammation","RO1138452 (CAY10441) is a potent and selective antagonist of IP (prostacyclin, PGI2) receptor with pKi of 9.3 and 8.7 in human platelets and a recombinant IP receptor system, respectively.",309.41,"221529-58-4",{"v":62,"d":"62.00"},200.38,"<1","N/A","https://www.selleckchem.com/products/ro1138452-cay10441.html","C19H23N3O","free base","CAY10441","CC(C)OC1=CC=C(CC2=CC=C(NC3=NCCN3)C=C2)C=C1",3.709,2,2,6]
["S0325","Treprostinil sodium","b4","L4000-17","in 10mM DMSO","Prostaglandin Receptor","GPCR & G Protein","Treprostinil sodium (UT-15, Remodulin, Orenitram, Tyvaso, Trevyent) is a potent agonist of DP1, EP2 and IP receptors with Ki 4.4 nM, 3.6 nM and 32 nM, respectively.",412.49,"289480-64-4",{"v":82,"d":"82.00"},198.79,{"v":82,"d":"82.00"},198.79,"http://www.selleckchem.com/products/treprostinil-sodium.html","C23H33NaO5","sodium","UT-15, Remodulin, Orenitram, Tyvaso, Trevyent","CCCCCC(O)CCC1C(O)CC2CC3=C(OCC(=O)O[Na])C=CC=C3CC12",4.526,3,2,11]
["S0398","Astemizole","c4","L4000-17","in 10mM DMSO","Histamine Receptor,Potassium Channel","Neuronal Signaling","Astemizole (R 43512) is a histamine H1-receptor antagonist with IC50 of 4.7 nM. Astemizole is also a potent inhibitor of ether à-go-go 1 (Eag1) and Eag-related gene (Erg) potassium channels. Astemizole has antineoplastic and antipruritic effects.",458.57,"68844-77-9",{"v":92,"d":"92.00"},200.62,"<1","N/A","http://www.selleckchem.com/products/astemizole.html","C28H31FN4O","free base","R 43512","COC1=CC=C(CCN2CCC(CC2)NC3=NC4=CC=CC=C4[N]3CC5=CC=C(F)C=C5)C=C1",5.689,2,1,8]
["S0405","AF-353","d4","L4000-17","in 10mM DMSO","P2 Receptor","Neuronal Signaling","AF-353 (Ro-4) is a potent, selective and orally bioavailable antagonist of P2X3 receptor and P2X2/3 receptor with pIC50 of 8.06, 8.05 and 7.41 for human P2X3, rat P2X3 and human P2X2/3, respectively.",400.21,"865305-30-2",{"v":100,"d":"100.00"},249.87,"<1","N/A","http://www.selleckchem.com/products/af353.html","C14H17IN4O2","free base","Ro-4","COC1=C(I)C=C(OC2=CN=C(N)N=C2N)C(=C1)C(C)C",2.934,4,2,4]
["S0457","DREADD agonist 21","e4","L4000-17","in 10mM DMSO","AChR","Neuronal Signaling","DREADD agonist 21 is a potent agonist of human muscarinic acetylcholine M3 receptors (hM3Dq) with EC50 of 1.7 nM.",278.35,"56296-18-5",{"v":56,"d":"56.00"},201.19,"<1","N/A","http://www.selleckchem.com/products/dreadd-agonist-21.html","C17H18N4","free base","N/A","C1CN(CCN1)C2=NC3=CC=CC=C3NC4=CC=CC=C24",2.222,1,2,1]
["S0758","BX430","f4","L4000-17","in 10mM DMSO","P2 Receptor","Neuronal Signaling","BX430 is a potent and selective noncompetitive allosteric antagonist of human P2X4 receptor channels with IC50 of 0.54 μM. BX430 is a potent antagonist of zebrafish P2X4 but has no effect on rat and mouse P2X4 orthologs. BX430 is used for chronic pain and cardiovascular disease.",413.11,"688309-70-8",{"v":83,"d":"83.00"},200.92,"<1","N/A","http://www.selleckchem.com/products/bx430.html","C15H15Br2N3O","free base","N/A","CC(C)C1=CC(=C(NC(=O)NC2=CC=CN=C2)C(=C1)Br)Br",4.063,2,2,3]
["S0924","Pteryxin","g4","L4000-17","in 10mM DMSO","BChE,NOS","Neuronal Signaling","Pteryxin ((+)-Pteryxin), a dihydropyranocoumarin derivative found in Apiaceae family, is a potent inhibitor of butyrylcholinesterase (BChE) with IC50 of 12.96 μg/ml. Pteryxin inhibits LPS-induced nitric oxide production in mouse peritoneal macrophages with IC50 of 20 µM. Pteryxin is potential for Alzheimer's disease (AD) treatment.",{"v":386.4,"d":"386.40"},"13161-75-6",{"v":100,"d":"100.00"},{"v":258.8,"d":"258.80"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/pteryxin.html","C21H22O7","free base","(+)-Pteryxin","C\\C=C(C)/C(=O)OC1C(OC(C)=O)C(C)(C)OC2=C1C3=C(C=CC(=O)O3)C=C2",3.502,7,0,5]
["S0973","Wilforgine","h4","L4000-17","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Wilforgine, one of the major bioactive sesquiterpene alkaloids in Tripterygium wilfordii Hook. F., induces microstructural and ultrastructural changes in the muscles of M. separata larvae, and the sites of action are proposed to be calcium receptors or channels in the muscular system.",857.81,"37239-47-7",{"v":100,"d":"100.00"},116.58,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/wilforgine.html","C41H47NO19","free base","N/A","CC1CCC2=C(C=CC=N2)C(=O)OCC3(C)OC45C(OC(C)=O)C3C(OC(C)=O)C(OC(C)=O)C4(COC(C)=O)C(OC(C)=O)C(OC(=O)C6=COC=C6)C(OC1=O)C5(C)O",0.609,19,0,14]
["S3216","Uridine 5'-diphosphoglucose disodium salt","a5","L4000-17","in 10mM DMSO","P2 Receptor","Neuronal Signaling","Uridine-5'-diphosphoglucose (UDPG, UDP-Glc, UDP-D-Glucose, UDP-α-D-Glucose) activates the P2Y(14) receptor, a neuroimmune system GPCR. Uridine-5'-diphosphoglucose is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms.",610.27,"28053-08-9",{"v":100,"d":"100.00"},163.86,{"v":100,"d":"100.00"},163.86,"http://www.selleckchem.com/products/uridine-5-diphosphoglucose-disodium-salt.html","C15H22N2Na2O17P2","disodium","UDPG, UDP-Glc, UDP-D-Glucose disodium salt, UDP-α-D-Glucose sodium salt","OCC1OC(O[P](=O)(O[Na])O[P](=O)(O[Na])OCC2OC(C(O)C2O)N3C=CC(=O)NC3=O)C(O)C(O)C1O",-4.744,9,7,11]
["S3217","Brilliant Blue G","b5","L4000-17","in 10mM DMSO","Dyes,P2 Receptor","Neuronal Signaling","Brilliant Blue G (BBG) is a potent non-competitive antagonist of P2X7 receptor with IC50 of 10.1 nM and 265 nM for rat P2X7 and human P2X7, respectively. Brilliant Blue G is a dye which is commonly used in laboratories to stain or quantify proteins.",854.02,"6104-58-1",{"v":100,"d":"100.00"},117.09,{"v":100,"d":"100.00"},117.09,"http://www.selleckchem.com/products/brilliant-blue-g.html","C47H48N3NaO7S2","free base","BBG","[Na+].CCOC1=CC=C(NC2=CC=C(C=C2)\\C(C3=CC=C(C=C3C)N(CC)CC4=CC=CC(=C4)[S]([O-])(=O)=O)=C/5C=CC(/C=C5C)=[N+](/CC)CC6=CC=CC(=C6)[S]([O-])(=O)=O)C=C1",5.617,1,1,15]
["S3235","Sinapine","c5","L4000-17","in 10mM DMSO","P-gp","Transmembrane Transporters","Sinapine is an alkaloid isolated from seeds of the cruciferous species with antioxidant, antitumor and radio-protective activities. Sinapine inhibits the proliferation of Caco-2 cells via downregulation of P-glycoprotein.",310.36,"18696-26-9",{"v":100,"d":"100.00"},322.21,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/sinapine.html","C16H24NO5","free base","N/A","COC1=C(O)C(=CC(=C1)\\C=C\\C(=O)OCC[N+](C)(C)C)OC",0.662,4,1,8]
["S3236","Mesaconitine","d5","L4000-17","in 10mM DMSO","Apoptosis related,Calcium Channel,TNF-alpha","Transmembrane Transporters","Mesaconitine, one of the aconite alkaloids in Aconiti tuber, increases the [Ca2+]i level in endothelial cells by influx of Ca2+ from extracellular spaces.",631.71,"2752-64-9",{"v":12,"d":"12.00"},{"v":19,"d":"19.00"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/mesaconitine.html","C33H45NO11","free base","N/A","COCC12CN(C)C3C4C(OC)C1C3(C(CC2O)OC)C5CC6(O)C(OC)C(O)C4(OC(C)=O)C5C6OC(=O)C7=CC=CC=C7",-1.327,8,2,10]
["S3245","Nodakenetin","e5","L4000-17","in 10mM DMSO","AChR,Aldose Reductase,Apoptosis related,BACE,BChE,Bcl-2,Carbohydrate Metabolism,phosphatase","Metabolism","Nodakenetin (NANI), a plant-derived coumarin isolated from Angelica decursiva, inhibits α-glucosidase, PTP1B, rat lens aldose reductase (RLAR), AChE, BChE, and β-site amyloid precursor protein cleaving enzyme 1 (BACE1). Nodakenetin alters the protein expression of Bax and Bcl-2, and prompts mitochondrial apoptosis. Nodakenetin exhibits anti-tumor activity.",246.26,"495-32-9",{"v":100,"d":"100.00"},406.07,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/nodakenetin.html","C14H14O4","free base","NANI","CC(C)(O)C1CC2=C(O1)C=C3OC(=O)C=CC3=C2",2.029,3,0,1]
["S3246","Picfeltarraenin IB","f5","L4000-17","in 10mM DMSO","AChR","Neuronal Signaling","Picfeltarraenin IB, a cucurbitacin glycoside isolated from Picriafel-terrae, is an inhibitor of acetylcholinesterase (AChE). Picfeltarraenin IB can be used for the treatment of herpes infections, cancer and inflammation.",792.95,"97230-46-1",{"v":100,"d":"100.00"},126.11,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/picfeltarraenin-ib.html","C42H64O14","free base","N/A","CC(C)C1=CC(=O)C(CO1)C2C(O)CC3(C)C4CC=C5C(CCC(OC6OC(CO)C(O)C(O)C6OC7OC(C)C(O)C(O)C7O)C5(C)C)C4(C)C(=O)CC23C",1.051,7,7,7]
["S3255","Pectolinarigenin","g5","L4000-17","in 10mM DMSO","COX,Lipoxygenase","Immunology & Inflammation","Pectolinarigenin, an active anti-inflammatory ingredient in Cirsium chanroenicum, is a dual inhibitor of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX).",314.29,"520-12-7",{"v":100,"d":"100.00"},318.18,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/pectolinarigenin.html","C17H14O6","free base","N/A","COC1=CC=C(C=C1)C2=CC(=O)C3=C(O)C(=C(O)C=C3O2)OC",2.619,4,2,3]
["S3261","Myrislignan","h5","L4000-17","in 10mM DMSO","Anti-infection,COX,Interleukins,NF-κB,NOS,TNF-alpha","Immunology & Inflammation","Myrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan inhibits interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α). Myrislignan significantly inhibits the expressions of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) dose-dependently in LPS-stimulated macrophage cells. Myrislignan inhibits the NF-κB signalling pathway activation.",374.43,"171485-39-5",{"v":100,"d":"100.00"},267.07,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/myrislignan.html","C21H26O6","free base","N/A","COC1=C(O)C=CC(=C1)C(O)C(C)OC2=C(OC)C=C(CC=C)C=C2OC",{"v":3.98,"d":"3.980"},4,2,9]
["S3273","Hypericin","a6","L4000-17","in 10mM DMSO","Hydroxylase,MAO,P450 (e.g. CYP17),PKC,Reverse Transcriptase,Telomerase","Metabolism","Hypericin (Hyp, HY) is a naturally occurring substance found in the common St. John's Wort (Hypericum species) with antidepressive, antineoplastic and antiviral (human immunodeficiency and hepatitis C virus) activities. Hypericin has inhibitory effects on MAO (monoaminoxidase), PKC (protein kinase C), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450).",504.44,"548-04-9",{"v":100,"d":"100.00"},198.24,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/hypericin.html","C30H16O8","free base","Hyp, HY","CC1=C2C3=C(C)C=C(O)C4=C3C5=C6C2=C(C(=C1)O)C(=O)C7=C6C(=C(O)C=C7O)C8=C(O)C=C(O)C(=C58)C4=O",{"v":5.04,"d":"5.040"},2,6,0]
["S3283","Marmesin","b6","L4000-17","in 10mM DMSO","COX,Lipoxygenase","Immunology & Inflammation","Marmesin (S-(+)-Marmesin, (+)-Marmesin, (S)-Marmesin) is a natural coumarin with COX-2 and 5-LOX dual inhibitory activity.",246.26,"13849-08-6",{"v":100,"d":"100.00"},406.07,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/marmesin.html","C14H14O4","free base","S-(+)-Marmesin, (+)-Marmesin, (S)-Marmesin","CC(C)(O)C1CC2=CC3=C(OC(=O)C=C3)C=C2O1",2.029,3,0,1]
["S3291","Myristicin","c6","L4000-17","in 10mM DMSO","MAO,P450 (e.g. CYP17)","Metabolism","Myristicin (Myristicine), a terpene-like active component in Nutmeg which is the seed of Myristica fragrans, is a weak inhibitor of monamine oxidase (MAO) and a mechanism-based inhibitor of CYP1A2.",192.21,"607-91-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/myristicin.html","C11H12O3","free base","Myristicine","COC1=C2OCOC2=CC(=C1)CC=C",2.589,3,0,3]
["S3293","Gardenoside","d6","L4000-17","in 10mM DMSO","Interleukins,NF-κB,P2 Receptor,TNF-alpha","Immunology & Inflammation","Gardenoside is a natural compound extracted from Gardenia fruits, with hepatoprotective properties. Gardenoside inhibits TNF-α, IL-1β, IL-6 and NFκB activation. Gardenoside also has an inhibitory effect on free fatty acids (FFA)-induced cellular steatosis. Gardenoside suppresses the pain in rats model of chronic constriction injury by regulating the P2X3 and P2X7 receptors.",404.37,"24512-62-7",{"v":81,"d":"81.00"},200.31,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/gardenoside.html","C17H24O11","free base","N/A","COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C3C1C=CC3(O)CO",-2.975,5,5,6]
["S3294","Demethyl-Coclaurine","e6","L4000-17","in 10mM DMSO","Adrenergic Receptor,Akt,Apoptosis related,PI3K","Endocrinology & Hormones","Demethyl-Coclaurine (Higenamine, Norcoclaurine), the key component of the Chinese herb aconite root, is a beta-2 adrenergic receptor (β2-AR) agonist. Demethyl-Coclaurine stimulates AKT phosphorylation and requires PI3K activation for the anti-apoptotic effect in cardiomyocytes.",271.31,"5843-65-2",{"v":100,"d":"100.00"},368.58,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/demethyl-coclaurine.html","C16H17NO3","free base","Higenamine, Norcoclaurine","OC1=CC=C(CC2NCCC3=CC(=C(O)C=C23)O)C=C1",2.649,0,4,2]
["S3298","Caulophylline (N-Methylcytisine)","f6","L4000-17","in 10mM DMSO","AChR,IκB/IKK,NF-κB,Peroxidases","Neuronal Signaling","Caulophylline (N-Methylcytisine, Caulophyllin, NMC) is a tricyclic quinolizidine alkaloid with anti-inflammatory activities. Caulophylline binds to nicotinic acetylcholine receptors (nAChR) from squid optical ganglia with Kd of 50 nM. Caulophylline significantly reduces myeloperoxidase (MPO) activity, blocks the activation of NF-κB by inhibiting IκB and IKK phosphorylation.",204.27,"486-86-2 (63699-79-6, 207-643-8)",{"v":100,"d":"100.00"},489.55,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/caulophylline-n-methylcytisine-.html","C12H16N2O","free base","Caulophyllin, NMC","CN1CC2CC(C1)C3=CC=CC(=O)N3C2",0.198,1,0,0]
["S6664","Gefapixant","g6","L4000-17","in 10mM DMSO","P2 Receptor","Neuronal Signaling","Gefapixant (AF-219, MK-7264, R1646, RG-1646, RO 4926219) is an orally active small molecule antagonist of human P2X3 receptor with IC50 of about 30 nM, 100–250 nM for recombinant hP2X3 homotrimers and hP2X2/3 heterotrimeric receptors, respectively. Gefapixant has shown promise for the treatment of refractory and unexplained chronic cough.",{"v":353.4,"d":"353.40"},"1015787-98-0",{"v":71,"d":"71.00"},200.91,"<1","N/A","http://www.selleckchem.com/products/gefapixant.html","C14H19N5O4S","free base","AF-219, MK-7264, R1646,RG-1646,RO 4926219","COC1=CC(=C(OC2=CN=C(N)N=C2N)C=C1[S](N)(=O)=O)C(C)C",1.061,6,3,5]
["S6760","LM22B-10","h6","L4000-17","in 10mM DMSO","Akt,ERK,Trk receptor","Protein Tyrosine Kinase","LM22B-10 is a small molecule TrkB/TrkC neurotrophin receptor co-activator, LM22B-10 selectively activates TrkB, TrkC, AKT and ERK in vivo and in vitro.",485.01,"342777-54-2",{"v":97,"d":"97.00"},{"v":200,"d":"200.00"},"<1","N/A","http://www.selleckchem.com/products/lm2b-10.html","C27H33ClN2O4","free base","N/A","OCCN(CCO)C1=CC=C(C=C1)C(C2=CC=C(Cl)C=C2)C3=CC=C(C=C3)N(CCO)CCO",3.919,0,4,13]
["S6803","1-BCP","a7","L4000-17","in 10mM DMSO","GluR","Neuronal Signaling","1-BCP (Piperonylic acid piperidide) is a memory-enhancing agent that enhances AMPA-induced currents.",233.26,"34023-62-6",{"v":47,"d":"47.00"},201.49,{"v":6,"d":"6.00"},25.72,"http://www.selleckchem.com/products/1-bcp.html","C13H15NO3","free base","Piperonylic acid piperidide","O=C(N1CCCCC1)C2=CC=C3OCOC3=C2",1.929,3,0,1]
["S6850","NE 52-QQ57","b7","L4000-17","in 10mM DMSO","cAMP,COX,GPR,Interleukins,NOS,PGES,TNF-alpha","GPCR & G Protein","NE 52-QQ57 is a selective, and orally available antagonist of G-protein coupled receptor 4 (GPR4) with IC50 of 0.07 μM. NE 52-QQ57 effectively blocks GPR4-mediated cAMP accumulation with IC50 of 26.8 nM in HEK293 cells. The antagonism of GPR4 with NE 52-QQ57 significantly inhibits the AGE-induced increased expression of several key inflammatory cytokines and signaling molecules, including tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6, inducible nitric oxide synthase (iNOS), nitric oxide (NO), cyclooxygenase 2 (COX2), and prostaglandin E2 (PGE2).",416.52,"1401728-56-0",{"v":20,"d":"20.00"},48.02,"<1","N/A","http://www.selleckchem.com/products/ne-52-qq57.html","C24H28N6O","free base","N/A","CCC1=N[N]2C(=CC(=NC2=C1CC3=CC=C(C=C3)C4=NN=C(O4)C5CCNCC5)C)C",3.242,5,1,5]
["S6853","ONC206","c7","L4000-17","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","ONC206 is a selective antagonist of  DRD2/3/4 with broad-spectrum anti-tumor activity.",408.44,"1638178-87-6",{"v":82,"d":"82.00"},200.76,"<1","N/A","http://www.selleckchem.com/products/onc206.html","C23H22F2N4O","free base","N/A","FC1=CC(=C(CN2C(=O)C3=C(CCN(CC4=CC=CC=C4)C3)N5CCN=C25)C=C1)F",3.137,2,0,4]
["S6906","Capric acid","d7","L4000-17","in 10mM DMSO","GluR,PPAR","Neuronal Signaling","Capric acid (DA, Decanoic acid, Decylic acid), a component of medium-chain triclycerides occurring naturally in coconut oil and palm kernel oil, contributes to seizure control through direct AMPA receptor inhibition. Capric acid is also a modulating ligand for PPARs. Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.",172.26,"334-48-5",{"v":34,"d":"34.00"},197.38,{"v":34,"d":"34.00"},197.38,"http://www.selleckchem.com/products/capric-acid.html","C10H20O2","free base","DA, Decanoic acid, Decylic acid","CCCCCCCCCC(O)=O",3.655,1,0,8]
["S6910","Preladenant","e7","L4000-17","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","Preladenant (Privadenant, SCH 420814, MK-3814) is a potent, competitive and selective antagonist of the human adenosine A2A receptor with Ki of 1.1 nM.",503.56,"377727-87-2",{"v":8,"d":"8.00"},15.89,"<1","N/A","http://www.selleckchem.com/products/preladenant.html","C25H29N9O3","free base","Privadenant, SCH 420814, MK-3814","COCCOC1=CC=C(C=C1)N2CCN(CC2)CC[N]3N=CC4=C3N=C(N)[N]5N=C(N=C45)C6=CC=CO6",2.456,7,1,9]
["S7394","MDL-28170","f7","L4000-17","in 10mM DMSO","Cysteine Protease","Proteases","MDL-28170 (Calpain Inhibitor III) is a potent and selective calpain inhibitor of calpain that penetrates the blood-brain barrier and inhibits brain cysteine protease activity after systemic administration. MDL-28170 is also an inhibitor of γ-secretase.",382.45,"88191-84-8",{"v":76,"d":"76.00"},198.72,"<1","N/A","http://www.selleckchem.com/products/mdl-28170.html","C22H26N2O4","free base","Calpain Inhibitor III","CC(C)C(NC(=O)OCC1=CC=CC=C1)C(=O)NC(CC2=CC=CC=C2)C=O",3.531,4,2,10]
["S9662","UNC2025","g7","L4000-17","in 10mM DMSO","Axl,c-Kit,c-Met,FLT3,Mertk,Trk receptor,Tyro3","Protein Tyrosine Kinase","UNC2025 is a potent and orally active dual inhibitor of FLT3 and MER with IC50 of 0.35 nM and 0.46 nM, respectively. UNC2025 also inhibits AXL, TRKA, TRKC, QIK, TYRO3, SLK, NuaK1, Kit (c-Kit) and Met (c-Met) with IC50 of 1.65 nM, 1.67 nM, 4.38 nM, 5.75 nM, 5.83 nM, 6.14 nM, 7.97 nM, 8.18 nM and 364 nM, respectively.",476.66,"1429881-91-3",{"v":100,"d":"100.00"},209.79,"<1","N/A","http://www.selleckchem.com/products/unc2025.html","C28H40N6O","free base","N/A","CCCCNC1=NC=C2C(=N1)[N](C=C2C3=CC=C(CN4CCN(C)CC4)C=C3)C5CCC(O)CC5",4.578,2,2,8]
["S0000","Cav 2.2 blocker 1","h7","L4000-17","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain with IC50 of 0.001 μM.",424.96,"1567335-29-8",{"v":12,"d":"12.00"},28.24,"<1","N/A","https://www.selleckchem.com/products/cav-2-2-blocker-1.html","C25H29ClN2O2","Free Base","compound 9","COC1=CC=CC=C1[N]2N=C(C=C2C3=CC=C(Cl)C=C3)C4CC(C)(C)OC(C)(C)C4",6.318,3,0,4]
["S0106","BD-1047 dihydrobromide","a8","L4000-17","in 10mM DMSO","Sigma Receptor","GPCR & G Protein","BD-1047 dihydrobromide (HBr) is a selective functional antagonist of sigma-1 (σ1) receptor, shows antipsychotic activity in animal models predictive of efficacy in schizophrenia.",437.04,"138356-21-5",{"v":50,"d":"50.00"},114.41,{"v":87,"d":"87.00"},199.07,"https://www.selleckchem.com/products/bd-1047-dihydrobromide.html","C13H22Br2Cl2N2","Dihydrobromide","BD-1047 HBr","Br.Br.CN(C)CCN(C)CCC1=CC(=C(Cl)C=C1)Cl",4.674,0,0,6]
["S0141","NQ301","b8","L4000-17","in 10mM DMSO","CD markers,Prostaglandin Receptor","Transmembrane Transporters","NQ301 (Compound 211), an antiplatelet and antithrombotic agent, is a selective CD45 inhibitor with IC50 of 200 nM. NQ301 inhibits thromboxane A2 receptor (TXA2) and synthase activity in rabbit platelets.",325.75,"130089-98-4",{"v":30,"d":"30.00"},{"v":92.1,"d":"92.10"},"<1","N/A","https://www.selleckchem.com/products/nq301.html","C18H12ClNO3","Free Base","N/A","CC(=O)C1=CC=C(NC2=C(Cl)C(=O)C3=CC=CC=C3C2=O)C=C1",2.955,3,1,3]
["S0165","Ampalex (CX-516)","c8","L4000-17","in 10mM DMSO","GluR","Neuronal Signaling","Ampalex (CX-516, Ampakine CX 516, BDP-12, SPD 420) is a positive allosteric modulator of AMPA receptor. Ampalex exhibits potential treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI).",241.29,"154235-83-3",{"v":48,"d":"48.00"},198.93,{"v":48,"d":"48.00"},198.93,"https://www.selleckchem.com/products/cx-516.html","C14H15N3O","Free Base","Ampakine CX 516, BDP-12, SPD 420","O=C(N1CCCCC1)C2=CC3=NC=CN=C3C=C2",1.625,3,0,1]
["S0412","Bay 59-3074","d8","L4000-17","in 10mM DMSO","Cannabinoid Receptor","GPCR & G Protein","Bay 59-3074 is a selective cannabinoid CB1/CB2 receptor partial agonist with Ki of 55.4 nM, 48.3 nM and 45.5 nM at rat and human CB1 and human CB2 receptors, respectively. Bay 59-3074 displays analgesic properties.",453.36,"406205-74-1",{"v":91,"d":"91.00"},200.72,"<1","N/A","https://www.selleckchem.com/products/bay-59-3074.html","C18H13F6NO4S","Free Base","N/A","FC(F)(F)CCC[S](=O)(=O)OC1=CC=CC(=C1)OC2=CC=CC(=C2C#N)C(F)(F)F",5.354,2,0,9]
["S0486","Hoechst 34580","e8","L4000-17","in 10mM DMSO","Beta Amyloid,Dyes","Neuronal Signaling","Hoechst 34580 (HOE 34580) is a cell-permeable blue fluorescent dye to stain DNA and nuclei. Hoechst 34580 is also a good candidate for treating the Alzheimer's disease by inhibiting amyloid beta (Aβ) formation with IC50 of 0.86 μM.",451.57,"23555-00-2",{"v":5,"d":"5.00"},11.07,{"v":90,"d":"90.00"},{"v":199.3,"d":"199.30"},"https://www.selleckchem.com/products/hoechst-34580.html","C27H29N7","Free Base","HOE 34580","CN1CCN(CC1)C2=CC3=C(C=C2)N=C([NH]3)C4=CC5=C(C=C4)N=C([NH]5)C6=CC=C(C=C6)N(C)C",4.992,2,2,4]
["S0495","BI-671800","f8","L4000-17","in 10mM DMSO","Prostaglandin Receptor","GPCR & G Protein","BI-671800 (AP-761, Cmpd A) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2) with IC50 of 4.5 nM and 3.7 nM for PGD2 binding to human CRTH2 and murine CRTH2, respectively. BI-671800 is associated with a small improvement in FEV1 in symptomatic controller-naïve asthma patients, and in patients on ICS.",{"v":501.5,"d":"501.50"},"1093108-50-9",{"v":100,"d":"100.00"},{"v":199.4,"d":"199.40"},"<1","N/A","https://www.selleckchem.com/products/ap-761-bi671800.html","C25H26F3N5O3","Free Base","AP-761, Cmpd A","CN(C)C1=NC(=NC(=C1CC(O)=O)N(C)C)CC2=CC=C(NC(=O)C3=CC=C(C=C3)C(F)(F)F)C=C2",{"v":4.5,"d":"4.500"},4,1,9]
["S0496","PF-04995274","g8","L4000-17","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","PF-04995274 (PF-4995274) is a potent, high-affinity, orally active and partial agonist of serotonin 4 receptor (5-HT4R) with EC50 of 0.47 nM, 0.36 nM, 0.37 nM and 0.26 nM for human 5-HT4A/4B/4D/4E, respectively. As for rat 5-HT4S/4L/4E, the EC50 is 0.59 nM, 0.65 nM and 0.62 nM, respectively. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease.",432.51,"1331782-27-4",{"v":86,"d":"86.00"},198.84,"<1","N/A","https://www.selleckchem.com/products/pf-04995274.html","C23H32N2O6","Free Base","PF-4995274","OC1(CCOCC1)CN2CCC(CC2)COC3=NOC4=C3C(=CC=C4)OC5CCOC5",1.615,6,0,7]
["S0498","Namodenoson (CF-102)","h8","L4000-17","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","Namodenoson (CF-102, 2-Cl-IB-MECA) is an orally bioavailable and selective agonist of the A3 adenosine receptor (A3AR) with Ki of 0.33 nM. Namodenoson exerts an anti‑NASH effect mediated via the de‑regulation of the PI3K/NF‑κB/Wnt/β‑catenin signaling pathway.",544.73,"163042-96-4",{"v":100,"d":"100.00"},183.58,"<1","N/A","https://www.selleckchem.com/products/namodenoson-cf-102.html","C18H18ClIN6O4","Free Base","2-Cl-IB-MECA","CNC(=O)C1OC(C(O)C1O)[N]2C=NC3=C2N=C(Cl)N=C3NCC4=CC=CC(=C4)I",1.398,5,4,5]
["S0541","Dazoxiben hydrochloride","a9","L4000-17","in 10mM DMSO","P450 (e.g. CYP17),PGES,Prostaglandin Receptor","Metabolism","Dazoxiben hydrochloride (HCl) is a potent, selevtive and orally active inhibitor of thromboxane (TX) synthase. Dazoxiben inhibits TXB2 production in clotting human whole blood with IC50 of 0.3 μM and causes parallel enhancement of PGE2 production.",{"v":268.7,"d":"268.70"},"74226-22-5",{"v":54,"d":"54.00"},200.97,{"v":54,"d":"54.00"},200.97,"https://www.selleckchem.com/products/dazoxiben.html","C12H13ClN2O3","Hydrochloride","Dazoxiben HCl","Cl.OC(=O)C1=CC=C(OCC[N]2C=CN=C2)C=C1",1.567,3,0,5]
["S0552","BNC210","b9","L4000-17","in 10mM DMSO","AChR","Neuronal Signaling","BNC210 (H-Ile-Trp-OH, IW-2143) is a negative allosteric modulator of alpha-7 nicotinic acetylcholine receptor (α7 nAChR).",317.38,"13589-06-5",{"v":63,"d":"63.00"},{"v":198.5,"d":"198.50"},"<1","N/A","https://www.selleckchem.com/products/bnc210.html","C17H23N3O3","Free Base","H-Ile-Trp-OH, IW-2143","CCC(C)C(N)C(=O)NC(CC1=C[NH]C2=CC=CC=C12)C(O)=O",-0.469,2,3,7]
["S0721","Ticlopidine","c9","L4000-17","in 10mM DMSO","Adenosine Receptor,P450 (e.g. CYP17)","Metabolism","Ticlopidine (Yuclid, Ticlopidinum, Ticlopidina,PCR 5332) is an orally active inhibitor of platelet aggregation induced by adenosine diphosphate (ADP). Ticlopidine is also an inhibitor of CYP2B6 with Ki of 0.2 μM.",263.79,"55142-85-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","https://www.selleckchem.com/products/ticlopidine.html","C14H14ClNS","Free Base","Yuclid, Ticlopidinum, Ticlopidina,PCR 5332","ClC1=CC=CC=C1CN2CCC3=C(C2)C=CS3",3.893,0,0,2]
["S0750","GFB-8438","d9","L4000-17","in 10mM DMSO","TRP Channel","Transmembrane Transporters","GFB-8438 is a novel, potent, and subtype selective TRP channel subfamily C (TRPC) inhibitor that is equipotent against TRPC4 and TRPC5 with IC50 of 0.18 μM and 0.29 μM, and shows excellent selectivity against TRPC6, other TRP family members , NaV 1.5, as well as limited activity against the hERG channel.",386.76,"2304549-73-1",{"v":77,"d":"77.00"},199.09,"<1","N/A","https://www.selleckchem.com/products/gfb-8438.html","C16H14ClF3N4O2","Free Base","N/A","FC(F)(F)C1=CC=CC=C1CN2CCN(CC2=O)C3=C(Cl)C(=O)NN=C3",1.445,3,1,4]
["S0759","FPL 62064","e9","L4000-17","in 10mM DMSO","COX,Lipoxygenase","Metabolism","FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and prostaglandin synthetase (cyclooxygenase, COX) with IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and seminal vesicle prostaglandin synthetase, respectively. FPL 62064 has potent anti-inflammatory activity.",265.31,"103141-09-9",{"v":53,"d":"53.00"},199.77,"<1","N/A","https://www.selleckchem.com/products/fpl-62064.html","C16H15N3O","Free Base","N/A","COC1=CC=C(NC2=N[N](C=C2)C3=CC=CC=C3)C=C1",4.129,2,1,4]
["S0766","RHC 80267","f9","L4000-17","in 10mM DMSO","AChR,COX,Phospholipase (e.g. PLA)","Neuronal Signaling","RHC 80267 (U-57908) is a potent and selective inhibitor of diacylglycerol lipase (DAGL, DAG lipase) with IC50 of 4 μM for cholinesterase activity. RHC 80267 inhibits cyclooxygenase (COX) activity, phospholipase C (PLC) activity and the hydrolysis of phosphatidylcholine (PC).",394.51,"83654-05-1",{"v":79,"d":"79.00"},200.25,"<1","N/A","https://www.selleckchem.com/products/rhc-80267.html","C20H34N4O4","Free Base","U-57908","O=C(NCCCCCCNC(=O)ON=C1CCCCC1)ON=C2CCCCC2",3.775,6,2,11]
["S0772","L-732138","g9","L4000-17","in 10mM DMSO","Neurokinin Receptor","GPCR & G Protein","L-732138 (L-732,138) is a selective, potent and competitive antagonist of neurokinin-1 (NK-1) receptor/substance P (SP) receptor. L-732138 inhibits the binding of 125I-SP to the human NK-1 receptor stably expressed in CHO cells with IC50 of 2.3 nM.",472.38,"148451-96-1",{"v":94,"d":"94.00"},198.99,"<1","N/A","https://www.selleckchem.com/products/l-732138.html","C22H18F6N2O3","Free Base","L-732,138","CC(=O)NC(CC1=C[NH]C2=CC=CC=C12)C(=O)OCC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F",4.882,3,2,9]
["S0782","VU0238441","h9","L4000-17","in 10mM DMSO","AChR","Neuronal Signaling","VU0238441 is a pan muscarinic acetylcholine receptor (mAChR) positive allosteric modulator (PAM) with EC50 of 2.1 μM, 2.2 μM, 2.8 μM, 3.2 μM and >10 μM for M5, M3, M2, M1 and M4, respectively.",{"v":339.7,"d":"339.70"},"85511-68-8",{"v":50,"d":"50.00"},147.19,"<1","N/A","https://www.selleckchem.com/products/vu0238441.html","C16H9ClF3NO2","Free Base","N/A","FC(F)(F)C1=CC=C(CN2C(=O)C(=O)C3=C2C(=CC=C3)Cl)C=C1",4.066,2,0,3]
["S0783","VU0119498","a10","L4000-17","in 10mM DMSO","AChR","Neuronal Signaling","VU0119498 is a pan Gq muscarinic acetylcholine receptor (mAChR) M1, M3, M5 positive allosteric modulator (PAM) with EC50 of 6.1 μM, 6.4 μM, 4.1 μM, respectively.",316.15,"79183-37-2",{"v":50,"d":"50.00"},158.15,"<1","N/A","https://www.selleckchem.com/products/vu0119498.html","C15H10BrNO2","Free Base","N/A","BrC1=CC=C(CN2C(=O)C(=O)C3=CC=CC=C23)C=C1",3.208,2,0,2]
["S0812","SR59230A","b10","L4000-17","in 10mM DMSO","Adrenergic Receptor","Endocrinology & Hormones","SR59230A is a blood-brain barrier penetrating, potent and selective antagonist of β3-adrenergic receptor with IC50 of 40 nM, 408 nM, and 648 nM for β3, β1, and β2 receptors, respectively.",415.48,"174689-39-5",{"v":83,"d":"83.00"},199.77,"<1","N/A","https://www.selleckchem.com/products/sr59230a.html","C23H29NO6","Free Base","N/A","CCC1=CC=CC=C1OCC(O)CNC2CCCC3=CC=CC=C23.OC(=O)C(O)=O",1.313,3,2,8]
["S0826","A-740003","c10","L4000-17","in 10mM DMSO","Interleukins,P2 Receptor","Neuronal Signaling","A-740003 is a potent, selective and competitive antagonist of P2X7 receptor with IC50 of 18 nM and 40 nM for rat and human P2X7 receptors, respectively. A-740003 potently blocks agonist-evoked IL-1β release and pore formation with IC50 of 156 nM and 92 nM in differentiated human THP-1 cells.",474.55,"861393-28-4",{"v":95,"d":"95.00"},200.19,"<1","N/A","https://www.selleckchem.com/products/a-740003.html","C26H30N6O3","Free Base","N/A","COC1=C(OC)C=C(CC(=O)NC(NC(NC2=CC=CC3=C2C=CC=N3)=NC#N)C(C)(C)C)C=C1",3.849,5,3,10]
["S0827","LM22A-4","d10","L4000-17","in 10mM DMSO","Trk receptor","Protein Tyrosine Kinase","LM22A-4 (LM 22A4) is a specific agonist of tyrosine kinase receptor B (TrkB) that reduces the development of tissue injury associated with spinal cord trauma.",339.34,"37988-18-4",{"v":68,"d":"68.00"},200.39,{"v":68,"d":"68.00"},200.39,"https://www.selleckchem.com/products/lm-22a4.html","C15H21N3O6","Free Base","LM 22A4","OCCNC(=O)C1=CC(=CC(=C1)C(=O)NCCO)C(=O)NCCO",-2.164,3,6,9]
["S0869","Carbetapentane","e10","L4000-17","in 10mM DMSO","Sigma Receptor","GPCR & G Protein","Carbetapentane (Pentoxyverine, CB) is an antitussive anticonvulsant nonselective sigma-1 (σ1) agonist.",333.46,"77-23-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","https://www.selleckchem.com/products/carbetapentane.html","C20H31NO3","Free Base","Pentoxyverine, CB","CCN(CC)CCOCCOC(=O)C1(CCCC1)C2=CC=CC=C2",3.845,3,0,11]
["S0870","Barnidipine","f10","L4000-17","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Barnidipine (Libradin, Mepirodipine, Vasexten, YM-09730-5, Cyress, Hypoca, Oldeca) is an antihypertensive drug that belongs to the dihydropyridine (DHP) group of calcium antagonist (CaA) with Ki of 0.21 nM for [3H]nitrendipine binding sites.",491.54,"104713-75-9",{"v":98,"d":"98.00"},199.37,"<1","N/A","https://www.selleckchem.com/products/barnidipine.html","C27H29N3O6","Free Base","Libradin, Mepirodipine, Vasexten, YM-09730-5, Cyress, Hypoca, Oldeca","COC(=O)C1=C(C)NC(=C(C1C2=CC(=CC=C2)[N+]([O-])=O)C(=O)OC3CCN(C3)CC4=CC=CC=C4)C",3.398,4,1,9]
["S0977","AC1903","g10","L4000-17","in 10mM DMSO","TRP Channel","Transmembrane Transporters","AC1903 (compound 2) is a specific and selective TRPC5 (transient receptor potential canonical channel 5) inhibitor with IC50 of 4.06 μM.",303.36,"831234-13-0",{"v":60,"d":"60.00"},197.78,"<1","N/A","https://www.selleckchem.com/products/ac1903.html","C19H17N3O","Free Base","N/A","C(NC1=NC2=CC=CC=C2[N]1CC3=CC=CC=C3)C4=CC=CO4",{"v":4.25,"d":"4.250"},2,1,5]
["S2953","Dooku1","h10","L4000-17","in 10mM DMSO","Mechanosensitive Channel","Transmembrane Transporters","Dooku1 is an analog of Yoda1 with antagonist activity against mechanosensitive Piezo1 channel. Dooku1 inhibits 2 μM Yoda1-induced Ca2+-entry with IC50 of 1.3 μM in HEK 293 cells and 1.5 μM in HUVECs, respectively.",{"v":326.2,"d":"326.20"},"2253744-54-4",{"v":65,"d":"65.00"},199.26,"<1","N/A","https://www.selleckchem.com/products/dooku1.html","C13H9Cl2N3OS","Free Base","N/A","ClC1=C(CSC2=NN=C(O2)C3=CC=C[NH]3)C(=CC=C1)Cl",{"v":4.51,"d":"4.510"},3,1,4]
["S2985","N-Acetyl-5-hydroxytryptamine","a11","L4000-17","in 10mM DMSO","Trk receptor","Proteases","N-Acetyl-5-hydroxytryptamine (NAS, N-Acetylserotonin, Normelatonin, O-Demethylmelatonin), a precursor of melatonin, is a potent and selective agonist of TrkB receptor.",218.25,"1210-83-9",{"v":43,"d":"43.00"},197.02,"<1","N/A","https://www.selleckchem.com/products/n-acetyl-5-hydroxytryptamine.html","C12H14N2O2","Free Base","NAS, N-Acetylserotonin, Normelatonin, O-Demethylmelatonin","CC(=O)NCCC1=C[NH]C2=C1C=C(O)C=C2",{"v":1.33,"d":"1.330"},1,3,3]
["S3311","Myosmine","b11","L4000-17","in 10mM DMSO","AChR","Neuronal Signaling","Myosmine is not only one of the minor tobacco alkaloids but is also present in various foods. Myosmine has low affinity against a4b2 nicotinic acetylcholinergic receptors (nAChR) with Ki of 3300 nM.",146.19,"532-12-7",{"v":29,"d":"29.00"},198.37,{"v":29,"d":"29.00"},198.37,"https://www.selleckchem.com/products/myosmine.html","C9H10N2","Free Base","N/A","C1CN=C(C1)C2=CN=CC=C2",0.935,2,0,1]
["S3370","3-Methoxytyramine hydrochloride","c11","L4000-17","in 10mM DMSO","Others","Others","3-Methoxytyramine (3-O-methyl Dopamine, 3MT) hydrochloride, a major extracellular metabolite of dopamine, is a neuromodulator that in certain situations may be involved in movement control.",203.67,"1477-68-5",{"v":40,"d":"40.00"},{"v":196.4,"d":"196.40"},{"v":40,"d":"40.00"},{"v":196.4,"d":"196.40"},"https://www.selleckchem.com/products/3-methoxytyramine-hydrochloride.html","C9H14ClNO2","Hydrochloride","3-O-methyl Dopamine hydrochloride, 3MT hydrochloride","Cl.COC1=C(O)C=CC(=C1)CCN",{"v":1.38,"d":"1.380"},1,2,3]
["S6907","Rapastinel (GLYX-13)","d11","L4000-17","in 10mM DMSO","NMDAR","Neuronal Signaling","Rapastinel (GLYX-13, BV-102, TPPT-amide) is a partial agonist of N-methyl-D-aspartate receptor (NMDAR) that targeting a glycine site. Rapastinel has long-lasting antidepressant effects.",413.47,"117928-94-6",{"v":83,"d":"83.00"},200.74,{"v":83,"d":"83.00"},200.74,"https://www.selleckchem.com/products/rapastinel.html","C18H31N5O6","Free Base","BV-102, TPPT-amide","CC(O)C(N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NC(C(C)O)C(N)=O",-3.063,4,5,7]
["S6920","SEA0400","e11","L4000-17","in 10mM DMSO","Calcium Channel,ERK,NCX,p38 MAPK,ROS,Sodium Channel","Transmembrane Transporters","SEA0400 is a selective and potent inhibitor of the Na+-Ca2+ exchanger (NCX) that inhibits Na+-dependent Ca2+ uptake in cultured neurons, astrocytes, and microglia with IC50 of 33 nM, 5.0 nM and 8.3 nM, respectively. SEA0400 prevents sodium nitroprusside (SNP) from increasing ERK and p38 MAPK phosphorylation and production of reactive oxygen species (ROS) in an extracellular Ca(2+)-dependent manner.",371.38,"223104-29-8",{"v":74,"d":"74.00"},199.26,"<1","N/A","https://www.selleckchem.com/products/sea0400.html","C21H19F2NO3","Free Base","N/A","CCOC1=CC=C(OC2=CC=C(OCC3=C(F)C=CC(=C3)F)C=C2)C(=C1)N",4.954,3,1,7]
["S6934","AMG-9810","f11","L4000-17","in 10mM DMSO","TLR,TRP Channel","Transmembrane Transporters","AMG-9810 is a potent, competitive and selective vanilloid receptor 1 (TRPV1) antagonist and inhibits capsaicin activation with IC50 of 24.5 nM and 85.6 nM for human TRPV1 and rat TRPV1, repectively. AMG-9810 blocks all known modes of TRPV1 activation, including protons-, heat-, and endogenous ligands, such as anandamide, N-arachidonyl dopamine, and oleoyldopamine. AMG-9810 significantly reduces the mRNA expression of TLR2 and TLR4. AMG-9810 also promotes mouse skin tumorigenesis mediated through EGFR/Akt/mTOR signaling.",337.41,"545395-94-6",{"v":67,"d":"67.00"},198.57,"<1","N/A","https://www.selleckchem.com/products/amg-9810.html","C21H23NO3","Free Base","N/A","CC(C)(C)C1=CC=C(/C=C/C(=O)NC2=CC=C3OCCOC3=C2)C=C1",4.268,3,1,4]
["S6948","Lanreotide","g11","L4000-17","in 10mM DMSO","GHSR","Endocrinology & Hormones","Lanreotide (Laromustine, Angiopeptin, BIM 23014, Dermopeptin, Ipstyl, ITM-014, Somatulina, Somatuline, Lanreotidum), an analog of the native somatostatin peptide, is a physiological inhibitor of growth hormone (GH). Lanreotide also has antitumoral effects.",1096.32,"108736-35-2",{"v":100,"d":"100.00"},91.21,{"v":100,"d":"100.00"},91.21,"https://www.selleckchem.com/products/lanreotide.html","C54H69N11O10S2","Free Base","Laromustine, Angiopeptin, BIM 23014, BIM 23014C, BM 23014, Dermopeptin, Ipstyl, ITM-014, ITM-014T, Somatulina, Somatuline, Lanreotidum","CC(C)C1NC(=O)C(CCCCN)NC(=O)C(CC2=C[NH]C3=C2C=CC=C3)NC(=O)C(CC4=CC=C(O)C=C4)NC(=O)C(CSSCC(NC1=O)C(=O)NC(C(C)O)C(N)=O)NC(=O)C(N)CC5=CC6=CC=CC=C6C=C5",1.704,8,13,17]
["S6950","PRE-084 hydrochloride","h11","L4000-17","in 10mM DMSO","Sigma Receptor","GPCR & G Protein","PRE-084 hydrochloride (HCl) is a potent, selective sigma-1 receptor (σ1, S1R) agonist with IC50 of 44 nM in the sigma receptor assay.",353.88,"75136-54-8",{"v":71,"d":"71.00"},200.63,{"v":16,"d":"16.00"},45.21,"https://www.selleckchem.com/products/pre-084-hydrochloride.html","C19H28ClNO3","Hydrochloride","PRE-084 HCl","Cl.O=C(OCCN1CCOCC1)C2(CCCCC2)C3=CC=CC=C3",3.804,3,0,6]
["S9271","Pulchinenoside A","a2","L4000-18","in 10mM DMSO","NMDAR","Neuronal Signaling","Pulchinenoside A (Anemoside A3), a natural triterpenoid saponin, is a AMPARs and NMDAR modulator.",750.96,"129724-84-1",{"v":100,"d":"100.00"},133.16,{"v":-1,"d":"-1.00"},"N/A","https://www.selleckchem.com/products/pulchinenoside-a.html","C41H66O12","Free Base","Anemoside A3","CC1OC(OC2C(O)C(O)COC2OC3CCC4(C)C(CCC5(C)C4CCC6C7C(CCC7(CCC56C)C(O)=O)C(C)=C)C3(C)CO)C(O)C(O)C1O",3.361,5,6,7]
["S9686","NBQX (FG9202)","b2","L4000-18","in 10mM DMSO","GluR","Neuronal Signaling","NBQX (FG9202, NNC 079202) is a highly selective and competitive antagonist of AMPA receptor (AMPAR) with anti-epileptic effect.",336.28,"118876-58-7",{"v":67,"d":"67.00"},199.24,"<1","N/A","https://www.selleckchem.com/products/nbqx.html","C12H8N4O6S","Free Base","NNC 079202","N[S](=O)(=O)C1=C2C(=CC=C1)C3=C(NC(=O)C(=O)N3)C=C2[N+]([O-])=O",-0.441,4,3,2]
["S9719","CB-103","c2","L4000-18","in 10mM DMSO","Notch","Neuronal Signaling","CB-103 is an orally active inhibitor of the Notch transcription activation complex. CB-103 produces Notch loss-of-function phenotypes in flies and mice and inhibits the growth of human breast cancer and leukemia xenografts.",242.32,"218457-67-1",{"v":48,"d":"48.00"},198.09,"<1","N/A","https://www.selleckchem.com/products/cb-103.html","C15H18N2O","Free Base","N/A","CC(C)(C)C1=CC=C(OC2=CC=C(N)C=N2)C=C1",3.432,2,1,3]
["S0032","Batefenterol","d2","L4000-18","in 10mM DMSO","AChR,Adrenergic Receptor","Neuronal Signaling","Batefenterol (GSK961081, TD-5959) is both a muscarinic receptor antagonist and a β2-adrenoceptor agonist with Ki of 1.4 nM, 1.3 nM and 3.7 nM for hM2, hM3 muscarinic receptors and hβ2-adrenoceptor, respectively.",740.24,"743461-65-6",{"v":100,"d":"100.00"},135.09,"<1","N/A","http://www.selleckchem.com/products/batefenterol.html","C40H42ClN5O7","Free Base","GSK961081, TD-5959","COC1=CC(=C(Cl)C=C1CNCC(O)C2=CC=C(O)C3=C2C=CC(=O)N3)NC(=O)CCN4CCC(CC4)OC(=O)NC5=C(C=CC=C5)C6=CC=CC=C6",4.546,5,6,14]
["S0717","Varenicline (CP 526555) dihydrochloride","e2","L4000-18","in 10mM DMSO","AChR","Neuronal Signaling","Varenicline (CP 526555, Chantix, Champix,CP 526555 dihydrochloride) dihydrochloride is a potent, partial agonist of α4β2 nicotinic acetylcholine receptor (nAChR) and α3β4 nAChR with EC50 of 2.3 μM and 55 μM, respectively. Varenicline dihydrochloride is a potent, full agonist of α7 nAChRs with EC50 of 18 μM. Varenicline is a prescription medication used for smoking cessation.",284.18,"866823-63-4",{"v":57,"d":"57.00"},200.58,{"v":57,"d":"57.00"},200.58,"http://www.selleckchem.com/products/varenicline-dihydrochloride.html","C13H15Cl2N3","Dihydrochloride","Chantix, Champix,CP 526555 dihydrochloride","Cl.Cl.C1NCC2CC1C3=CC4=NC=CN=C4C=C23",1.802,2,1,0]
["S0761","Desmethyl Celecoxib","f2","L4000-18","in 10mM DMSO","COX","Immunology & Inflammation","Desmethyl Celecoxib (compound 3b), an analog of Celecoxib with the optimal yield of 75%, is a selective inhibitor of cyclooxygenase-2 (COX-2) with anti-inflammatory activities.",367.35,"170569-87-6",{"v":73,"d":"73.00"},198.72,"<1","N/A","http://www.selleckchem.com/products/desmethyl-celecoxib.html","C16H12F3N3O2S","Free Base","N/A","N[S](=O)(=O)C1=CC=C(C=C1)[N]2N=C(C=C2C3=CC=CC=C3)C(F)(F)F",3.942,3,1,4]
["S0821","Pamicogrel","g2","L4000-18","in 10mM DMSO","COX","Immunology & Inflammation","Pamicogrel (KBT3022) is an inhibitor of cyclooxygenase (COX) with platelet anti-aggregatory properties.",448.53,"101001-34-7",{"v":45,"d":"45.00"},100.33,"<1","N/A","https://www.selleckchem.com/products/pamicogrel.html","C25H24N2O4S","Free Base","KBT3022","CCOC(=O)C[N]1C=CC=C1C2=NC(=C(S2)C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4",5.581,5,0,9]
["S2945","SCH-442416","h2","L4000-18","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","SCH-442416 is a selective antagonist of adenosine A2A receptor that binds to human and rat adenosine A2A receptors with Ki of 0.048 nM and 0.5 nM, respectively.",389.41,"316173-57-6",{"v":78,"d":"78.00"},{"v":200.3,"d":"200.30"},"<1","N/A","http://www.selleckchem.com/products/sch-442416.html","C20H19N7O2","Free Base","N/A","COC1=CC=C(CCC[N]2N=CC3=C2N=C(N)[N]4N=C(N=C34)C5=CC=CO5)C=C1",{"v":3.18,"d":"3.180"},6,1,6]
["S2995","4-Hydroxyphenylpyruvic acid","a3","L4000-18","in 10mM DMSO","COX","Immunology & Inflammation","4-Hydroxyphenylpyruvic acid (4-HPPA), an abundant colon metabolite of polyphenols, is a potent scavenger that suppresses levels of free radicals and cyclooxygenase-2 (COX-2) and contributes to reduced risk of colon cancer development.",180.16,"156-39-8",{"v":36,"d":"36.00"},199.82,"<1","N/A","http://www.selleckchem.com/products/4-hydroxyphenylpyruvic-acid.html","C9H8O4","Free Base","4-HPPA","OC(=O)C(=O)CC1=CC=C(O)C=C1",1.128,2,1,3]
["S3913","Pimethixene maleate","b3","L4000-18","in 10mM DMSO","5-HT Receptor,AChR,Adrenergic Receptor,Dopamine Receptor,Histamine Receptor","Neuronal Signaling","Pimethixene (Pimetixene) maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimethixene maleate inhibits 5-HT2A, 5-HT2B, 5-HT2C, 5-HT1A, 5-HT1B, 5-HT6, 5-HT7, Adrenergic α-1A, Dopamine D1 Receptor, Dopamine D2 Receptor, Dopamine D4.4 Receptor, Histamine H1 Receptor, Muscarinic M1 and Muscarinic M2 with pKi of 10.22, 10.44, 8.42, 7.63, < 5, 7.30, 7.28, 7.61, 6.37, 8.19, 7.54, 10.14, 8.61 and 9.38, respectively.",{"v":409.5,"d":"409.50"},"13187-06-9",{"v":82,"d":"82.00"},200.24,"<1","N/A","http://www.selleckchem.com/products/pimethixene-maleate.html","C23H23NO4S","Maleate","Pimetixene maleate","CN1CCC(CC1)=C2C3=CC=CC=C3SC4=CC=CC=C24.OC(=O)\\C=C/C(O)=O",1.498,2,0,2]
["S4423","Emamectin Benzoate","c3","L4000-18","in 10mM DMSO","Apoptosis related,DNA/RNA Synthesis,GABA Receptor","Neuronal Signaling","Emamectin Benzoate (EMB, MK-244) activates gamma-amino butyric acid (GABA) transporter. Emamectin Benzoate induces of reactive oxygen species (ROS)-mediated DNA damage and apoptosis.",1008.24,"155569-91-8",{"v":100,"d":"100.00"},99.18,"<1","N/A","http://www.selleckchem.com/products/emamectin-benzoate.html","C56H81NO15","Free Base","EMB, MK-244","CCC(C)C1OC2(CC3CC(C\\C=C(C)\\C(OC4CC(OC)C(OC5CC(OC)C(NC)C(C)O5)C(C)O4)C(C)/C=C/C=C/6COC7C(O)C(=CC(C(=O)O3)C67O)C)O2)C=CC1C.OC(=O)C8=CC=CC=C8",3.589,12,2,10]
["S4435","Metamizole sodium hydrate","d3","L4000-18","in 10mM DMSO","COX","Immunology & Inflammation","Metamizole (Dipyrone) sodium hydrate is a potent inhitior of cyclooxygenase (COX) with strong analgesic as well as antipyretic and spasmolytic properties.",351.35,"5907-38-0",{"v":70,"d":"70.00"},199.23,{"v":70,"d":"70.00"},199.23,"http://www.selleckchem.com/products/metamizole-sodium-hydrate.html","C13H18N3NaO5S","Sodium hydrate","Dipyrone sodium hydrate","O.[Na+].CN(C[S]([O-])(=O)=O)C1=C(C)N(C)N(C1=O)C2=CC=CC=C2",-2.076,1,0,4]
["S4481","Guanabenz","e3","L4000-18","in 10mM DMSO","Adrenergic Receptor","Endocrinology & Hormones","Guanabenz (GBZ, GA, Wytensin, Wy-8678,BR-750) is an orally active central alpha 2-adrenoceptor (α2 adrenergic receptor) agonist with antihypertensive action.",231.08,"5051-62-7",{"v":12,"d":"12.00"},51.93,"<1","N/A","http://www.selleckchem.com/products/guanabenz.html","C8H8Cl2N4","Free Base","GBZ, GA, Wytensin, Wy-8678,BR-750","NC(=N)N\\N=C\\C1=C(Cl)C=CC=C1Cl",2.192,1,2,3]
["S4483","Iproniazid phosphate","f3","L4000-18","in 10mM DMSO","MAO","Neuronal Signaling","Iproniazid (Marsilid, Iprazid) phosphate is a non-selective, irreversible monoamine oxidase (MAO) inhibitor (MAOI) that is used as an antidepressive agent.",277.21,"305-33-9",{"v":55,"d":"55.00"},198.41,{"v":55,"d":"55.00"},198.41,"http://www.selleckchem.com/products/iproniazid-phosphate.html","C9H16N3O5P","Phosphate","N/A","CC(C)NNC(=O)C1=CC=NC=C1.O[P](O)(O)=O",-0.347,2,2,3]
["S4486","Thiamine monochloride","g3","L4000-18","in 10mM DMSO","Vitamin","Metabolism","Thiamine (Vitamin B1) monochloride is an essential vitamin that plays an important role in cellular production of energy from ingested food and enhances normal neuronal actives.",300.81,"59-43-8",{"v":60,"d":"60.00"},199.46,{"v":60,"d":"60.00"},199.46,"http://www.selleckchem.com/products/thiamine-monochloride.html","C12H17ClN4OS","Monochloride","Vitamin B1","[Cl-].CC1=NC=C(C[N+]2=CSC(=C2C)CCO)C(=N1)N",-1.626,2,2,4]
["S4713","Atropine","h3","L4000-18","in 10mM DMSO","AChR","Neuronal Signaling","Atropine (Atropen, Atnaa, Tropine tropate, DL-Hyoscyamine) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with anti-myopia effect.",289.37,"51-55-8",{"v":58,"d":"58.00"},200.44,"<1","N/A","http://www.selleckchem.com/products/atropine.html","C17H23NO3","Free Base","N/A","CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",1.721,2,1,5]
["S5181","Levobupivacaine","a4","L4000-18","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Levobupivacaine (Chirocaine, (S)-(-)-Bupivacaine, L-(-)-Bupivacaine), the S (-)-enantiomer of bupivacaine, is a long-acting amide local anaesthetic used in analgesia and anaesthesia. Levobupivacaine exhibits effects on motor and sensory nerves by inhibiting the opening of voltage-gated sodium channels.",288.43,"27262-47-1",{"v":58,"d":"58.00"},201.09,"<1","N/A","http://www.selleckchem.com/products/levobupivacaine.html","C18H28N2O","Free Base","Chirocaine, (S)-(-)-Bupivacaine, L-(-)-Bupivacaine","CCCCN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",{"v":4.31,"d":"4.310"},1,1,5]
["S5184","Dexamethasone palmitate","b4","L4000-18","in 10mM DMSO","Anti-infection,Glucocorticoid Receptor","Endocrinology & Hormones","Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone (DXM), is a glucocorticoid receptor agonist with a 47-fold lower affinity for the glucocorticoid receptor than DXM. Dexamethasone palmitate (DXP) exhibits anti-inflammatory activity.",630.87,"14899-36-6",{"v":100,"d":"100.00"},158.51,"<1","N/A","http://www.selleckchem.com/products/dexamethasone-palmitate.html","C38H59FO6","Free Base","DXP","CCCCCCCCCCCCCCCC(=O)OCC(=O)C1(O)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C",8.684,4,1,18]
["S5185","Perospirone","c4","L4000-18","in 10mM DMSO","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Perospirone (SM-9018 free base) is an orally active antagonist of 5-hydroxytryptamine2 (5-HT2) receptor, dopamine2 (D2) receptor and 5-HT1A receptor with Ki of 0.6 nM, 1.4 nM and 2.9 nM, respectively.",426.57,"150915-41-6",{"v":85,"d":"85.00"},199.26,"<1","N/A","http://www.selleckchem.com/products/perospirone.html","C23H30N4O2S","Free Base","SM-9018 free base","O=C1C2CCCCC2C(=O)N1CCCCN3CCN(CC3)C4=NSC5=CC=CC=C45",4.041,3,0,6]
["S5191","Cinacalcet","d4","L4000-18","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Cinacalcet (AMG073, Sensipar, Cin) is an orally active, allosteric agonist of receptors for calcium (CaR) that increases the sensitivity of the CaR to Ca.",357.41,"226256-56-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/cinacalcet.html","C22H22F3N","Free Base","AMG073, Sensipar, Cin","CC(NCCCC1=CC(=CC=C1)C(F)(F)F)C2=CC=CC3=CC=CC=C23",5.956,0,1,7]
["S5192","S-(+)-Ketoprofen","e4","L4000-18","in 10mM DMSO","COX","Immunology & Inflammation","S-(+)-Ketoprofen (Compound 1, Actron, (S)-Ketoprofen, Dexketoprofen) is a potent inhibitor of cyclooxygenase (COX) with IC50 of 1.9 nM and 27 nM for COX-1 and COX-2, respectively.",254.28,"22161-81-5",{"v":51,"d":"51.00"},200.57,"<1","N/A","http://www.selleckchem.com/products/s-ketoprofen.html","C16H14O3","Free Base","Actron, (S)-Ketoprofen, Dexketoprofen","CC(C(O)=O)C1=CC(=CC=C1)C(=O)C2=CC=CC=C2",3.361,2,0,4]
["S5196","Promethazine","f4","L4000-18","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Promethazine is a potent histamine H1 receptor antagonist. Promethazine is a medication used in the management and treatment of allergic conditions, nausea and vomiting, motion sickness, and sedation. Promethazine exhibits antiparasitic properties.",284.42,"60-87-7",{"v":29,"d":"29.00"},101.96,"<1","N/A","http://www.selleckchem.com/products/promethazine.html","C17H20N2S","Free Base","N/A","CC(CN1C2=CC=CC=C2SC3=CC=CC=C13)N(C)C",{"v":4.39,"d":"4.390"},0,0,3]
["S5489","Prednisone acetate","g4","L4000-18","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Prednisone acetate (Betapar, Cortan, Deltasone, Fernisone, Meticorten, Prednisone 21-acetate) is a glucocorticoid steroid that can be used as a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties.",400.46,"125-10-0",{"v":27,"d":"27.00"},67.42,"<1","N/A","http://www.selleckchem.com/products/prednisone-acetate.html","C23H28O6","Free Base","Betapar, Cortan, Deltasone, Fernisone, Meticorten, Prednisone 21-acetate","CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)C=CC4(C)C3C(=O)CC12C",1.596,5,0,4]
["S5770","Pizotifen","h4","L4000-18","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Pizotifen (Pizotyline, BC-105) is a potent antagonist of 5-Hydroxytryptamine (5-HT, Serotonin) 5-HT2 receptor with a high affinity for 5-HT1C binding site.",295.44,"15574-96-6",{"v":20,"d":"20.00"},{"v":67.7,"d":"67.70"},"<1","N/A","http://www.selleckchem.com/products/pizotifen.html","C19H21NS","Free Base","Pizotyline, BC-105","CN1CCC(CC1)=C2C3=C(CCC4=CC=CC=C24)SC=C3",4.338,0,0,0]
["S5777","Ipratropium bromide monohydrate","a5","L4000-18","in 10mM DMSO","AChR","Neuronal Signaling","Ipratropium bromide (Atrovent, Sch 1000) monohydrate is an antagonist of muscarinic acetylcholine receptors (mAChR) with IC50 of 2.9 nM, 2.0 nM, and 1.7 nM for M1, M2, and M3 receptors, respectively.",430.38,"66985-17-9",{"v":86,"d":"86.00"},199.82,{"v":86,"d":"86.00"},199.82,"http://www.selleckchem.com/products/ipratropium-bromide-monohydrate.html","C20H32BrNO4","Monohydrate","Atrovent, Sch 1000 monohydrate","O.[Br-].CC(C)[N+]1(C)C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",-1.533,2,1,6]
["S5786","Bromfenac sodium hydrate","b5","L4000-18","in 10mM DMSO","COX","Immunology & Inflammation","Bromfenac sodium hydrate (Bromsite, Bromday, Prolensa, Xibrom), a brominated nonsteroidal anti-inflammatory drugs (NSAID) with strong in vitro anti-inflammatory potency, is a potent and orally active inhibitor of COX with IC50 of 5.56 nM and 7.45 nM for COX-1 and COX-2, respectively.",766.34,"120638-55-3",{"v":100,"d":"100.00"},130.49,{"v":100,"d":"100.00"},130.49,"http://www.selleckchem.com/products/bromfenac-sodium-hydrate.html","C30H28Br2N2Na2O9","Sodium hydrate","Bromsite, Bromday, Prolensa, Xibrom","O.O.O.[Na+].[Na+].NC1=C(CC([O-])=O)C=CC=C1C(=O)C2=CC=C(Br)C=C2.NC3=C(CC([O-])=O)C=CC=C3C(=O)C4=CC=C(Br)C=C4",2.231,2,2,8]
["S5789","Propafenone","c5","L4000-18","in 10mM DMSO","Adrenergic Receptor,Sodium Channel","Endocrinology & Hormones","Propafenone (SA-79) is an orally active sodium channel blocking agent and a beta-adrenoceptor (β-adrenergic receptor) antagonist. Propafenone offers a broad spectrum of activity in the treatment of cardiac arrhythmias.",341.44,"54063-53-5",{"v":68,"d":"68.00"},199.16,"<1","N/A","http://www.selleckchem.com/products/propafenone.html","C21H27NO3","Free Base","SA-79","CCCNCC(O)COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2",3.673,2,2,11]
["S5860","Larotrectinib","d5","L4000-18","in 10mM DMSO","Trk receptor","Protein Tyrosine Kinase","Larotrectinib (Vitrakvi, LOXO-101, ARRY-470) is an ATP-competitive, oral administered and highly selective inhibitor of the tropomyosin-related kinase (TRK) family receptors.",428.44,"1223403-58-4",{"v":86,"d":"86.00"},200.73,"<1","N/A","http://www.selleckchem.com/products/larotrectinib.html","C21H22F2N6O2","Free Base","Vitrakvi, LOXO-101, ARRY-470","OC1CCN(C1)C(=O)NC2=C3N=C(C=C[N]3N=C2)N4CCCC4C5=CC(=CC=C5F)F",1.981,3,2,3]
["S5864","Levocetirizine","e5","L4000-18","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Levocetirizine (LCZ, (R)-Cetirizine), the R-enantiomer of cetirizine, is an antagonist of histamine H(1) receptor.",388.89,"130018-77-8",{"v":78,"d":"78.00"},200.57,{"v":78,"d":"78.00"},200.57,"http://www.selleckchem.com/products/levocetirizine.html","C21H25ClN2O3","Free Base","LCZ, (R)-Cetirizine","OC(=O)COCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3",0.453,2,0,8]
["S5898","Efonidipine hydrochloride monoethanolate","f5","L4000-18","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Efonidipine (NZ-105) hydrochloride monoethanolate is an L- and T-type calcium channel blocker leading to vasodilation and decreased automaticity of the heart. Efonidipine hydrochloride monoethanolate also suppresses aldosterone secretion from the adrenal.",714.18,"111011-76-8",{"v":100,"d":"100.00"},140.02,"<1","N/A","http://www.selleckchem.com/products/efonidipine-hydrochloride-monoethanolate.html","C36H45ClN3O8P","Hydrochloride monoethanolate","NZ-105 hydrochloride monoethanolate","Cl.CCO.CC1=C(C(C2=CC(=CC=C2)[N+]([O-])=O)C(=C(C)N1)[P]3(=O)OCC(C)(C)CO3)C(=O)OCCN(CC4=CC=CC=C4)C5=CC=CC=C5",5.329,4,2,11]
["S5942","Bisoprolol","g5","L4000-18","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Bisoprolol is a cardioselective β1-adrenergic blocking agent used for secondary prevention of myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension.",325.44,"66722-44-9","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/bisoprolol.html","C18H31NO4","Free Base","N/A","CC(C)NCC(O)COC1=CC=C(COCCOC(C)C)C=C1",2.031,3,2,12]
["S5947","Amitriptyline","h5","L4000-18","in 10mM DMSO","5-HT Receptor,Histamine Receptor,Serotonin Transporter","Neuronal Signaling","Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. Amitriptyline is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. This product is a waxy solid.",{"v":277.4,"d":"277.40"},"50-48-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/amitriptyline.html","C20H23N","Free Base","MK-230, N-750, Ro41575","CN(C)CC\\C=C1/C2=C(CCC3=CC=CC=C13)C=CC=C2",4.772,0,0,3]
["S5949","Metoclopramide hydrochloride hydrate","a6","L4000-18","in 10mM DMSO","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Metoclopramide hydrochloride (Clorpa, Gimoti, Maxolon, Reglan) hydrate is primarily a Dopamine receptor antagonist, with 5HT3 receptor antagonist and 5HT4 receptor agonist activity, and used as an antiemetic and gastroprokinetic.",354.27,"54143-57-6",{"v":71,"d":"71.00"},200.41,{"v":71,"d":"71.00"},200.41,"http://www.selleckchem.com/products/metoclopramide-hydrochloride-hydrate.html","C14H25Cl2N3O3","Hydrochloride hydrate","Clorpa, Gimoti, Maxolon, Reglan","O.Cl.CCN(CC)CCNC(=O)C1=CC(=C(N)C=C1OC)Cl",{"v":1.95,"d":"1.950"},2,2,7]
["S5954","L-(-)-α-Methyldopa hydrate","b6","L4000-18","in 10mM DMSO","Adrenergic Receptor","Endocrinology & Hormones","L-(-)-α-Methyldopa (Methyldopa, MK-351) hydrate, a potent antihypertensive drug, is a selective agonist for α2-adrenergic receptors.",476.47,"41372-08-1",{"v":46,"d":"46.00"},96.54,"<1","N/A","http://www.selleckchem.com/products/l-a-methyldopa-hydrate.html","C20H32N2O11","Hydrate","Methyldopa hydrate, MK-351 hydrate","O.O.O.CC(N)(CC1=CC(=C(O)C=C1)O)C(O)=O.CC(N)(CC2=CC(=C(O)C=C2)O)C(O)=O",-4.176,2,6,6]
["S5955","Thiamine nitrate","c6","L4000-18","in 10mM DMSO","Vitamin","Metabolism","Thiamine (Vitamin B1) nitrate is an essential vitamin that plays an important role in cellular production of energy from ingested food and enhances normal neuronal actives.",327.36,"532-43-4",{"v":65,"d":"65.00"},198.56,{"v":20,"d":"20.00"},61.09,"http://www.selleckchem.com/products/thiamine-nitrate.html","C12H17N5O4S","Nitrate","Vitamin B1 nitrate","CC1=NC=C(C[N+]2=CSC(=C2C)CCO)C(=N1)N.[O-][N+]([O-])=O",-0.914,2,2,4]
["S5965","Urapidil","d6","L4000-18","in 10mM DMSO","5-HT Receptor,Adrenergic Receptor","Neuronal Signaling","Urapidil is an antihypertensive drug acting as an α1 adrenoreceptor antagonist and a 5-HT1A agonist.",387.48,"34661-75-1",{"v":77,"d":"77.00"},198.72,"<1","N/A","http://www.selleckchem.com/products/urapidil.html","C20H29N5O3","Free Base","N/A","COC1=CC=CC=C1N2CCN(CCCNC3=CC(=O)N(C)C(=O)N3C)CC2",1.426,3,1,7]
["S5966","Amlodipine maleate","e6","L4000-18","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Amlodipine (Amvaz, UK-48340) maleate is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.",524.95,"88150-47-4",{"v":100,"d":"100.00"},190.49,"<1","N/A","http://www.selleckchem.com/products/amlodipine-maleate.html","C24H29ClN2O9","Maleate","Amvaz, UK-48340 maleate","CCOC(=O)C1=C(COCCN)NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C.OC(=O)\\C=C/C(O)=O",-0.864,7,2,12]
["S5973","Methylprednisolone Acetate","f6","L4000-18","in 10mM DMSO","ACE,Apoptosis related,Autophagy,Glucocorticoid Receptor,Immunology & Inflammation related,Interleukins","Endocrinology & Hormones","Methylprednisolone (NSC-19987, Medrol) acetate is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.",416.51,"53-36-1",{"v":86,"d":"86.00"},206.48,"<1","N/A","http://www.selleckchem.com/products/methylprednisolone-acetate.html","C24H32O6","Free Base","NSC-19987 acetate, Medrol acetate","CC1CC2C3CCC(O)(C(=O)COC(C)=O)C3(C)CC(O)C2C4(C)C=CC(=O)C=C14",1.891,4,1,4]
["S5981","S(-)-Propranolol hydrochloride","g6","L4000-18","in 10mM DMSO","Adrenergic Receptor","Endocrinology & Hormones","(S)-(-)-Propranolol hydrochloride, the active enantiomer of propranolol, is a β-Adrenoceptor (β-Adrenergic Receptor) antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively.",{"v":295.8,"d":"295.80"},"4199-10-4",{"v":59,"d":"59.00"},199.46,{"v":59,"d":"59.00"},199.46,"http://www.selleckchem.com/products/s-propranolol-hydrochloride.html","C16H22ClNO2","Hydrochloride","Hemangeol, Inderal","Cl.CC(C)NCC(O)COC1=CC=CC2=CC=CC=C12",2.922,1,2,6]
["S8033","6-Iodopravadoline (AM630)","h6","L4000-18","in 10mM DMSO","Cannabinoid Receptor","GPCR & G Protein","6-Iodopravadoline (AM630) is a selective cannabinoid CB2 receptor antagonist with Ki of 31.2 nM.",504.36,"164178-33-0",{"v":50,"d":"50.00"},99.14,"<1","N/A","http://www.selleckchem.com/products/6-iodopravadoline.html","C23H25IN2O3","Free Base","N/A","COC1=CC=C(C=C1)C(=O)C2=C(C)[N](CCN3CCOCC3)C4=C2C=CC(=C4)I",4.267,3,0,6]
["S9742","Indisulam","a7","L4000-18","in 10mM DMSO","Carbonic Anhydrase,CDK","Metabolism","Indisulam (E7070), a sulfonamide anticancer agent, is a potent carbonic anhydrase (CA) inhibitor that inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX. Indisulam suppresses the expression of cyclin E and phosphorylation of CDK2, both of which are essential for the G1 to S transition.",385.85,"165668-41-7",{"v":77,"d":"77.00"},199.56,"<1","N/A","http://www.selleckchem.com/products/indisulam.html","C14H12ClN3O4S2","Free Base","E7070","N[S](=O)(=O)C1=CC=C(C=C1)[S](=O)(=O)NC2=C3[NH]C=C(Cl)C3=CC=C2",{"v":1.98,"d":"1.980"},4,3,4]
["S9789","JHU37152","b7","L4000-18","in 10mM DMSO","AChR","Neuronal Signaling","JHU37152 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.8 nM and 8.7 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 5 nM and 0.5 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.",358.84,"2369979-67-7",{"v":72,"d":"72.00"},200.65,"<1","N/A","http://www.selleckchem.com/products/jhu37152.html","C19H20ClFN4","Free Base","N/A","CCN1CCN(CC1)C2=NC3=CC(=CC=C3NC4=CC=CC(=C24)F)Cl",3.977,1,1,2]
["S9790","JHU37160","c7","L4000-18","in 10mM DMSO","AChR","Neuronal Signaling","JHU37160 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.9 nM and 3.6 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 18.5 nM and 0.2 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.",358.84,"2369979-68-8",{"v":72,"d":"72.00"},200.65,"<1","N/A","http://www.selleckchem.com/products/jhu37160.html","C19H20ClFN4","Free Base","N/A","CCN1CCN(CC1)C2=NC3=CC(=CC=C3NC4=C2C=CC=C4F)Cl",3.977,1,1,2]
["S0272","Derenofylline (SLV320)","d7","L4000-18","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","Derenofylline (SLV320) is a selective and potent adenosine A1 antagonist with Ki of 1 nM. Derenofylline shows selective for adenosine A1 over A2A, A2B, and A3 receptors with Ki of 398 nM, 3981 nM, and 200 nM, respectively.",308.38,"251945-92-3",{"v":62,"d":"62.00"},201.05,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/derenofylline.html","C18H20N4O","Free Base","N/A","OC1CCC(CC1)NC2=NC(=NC3=C2C=C[NH]3)C4=CC=CC=C4",3.133,2,3,3]
["S0326","Olodanrigan (EMA401)","e7","L4000-18","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Olodanrigan (EMA401, PD-126055, (S) PD-126055) is a highly selective, orally active, peripherally restricted antagonist of angiotensin II type 2 receptor (AT2R). Olodanrigan (EMA401) analgesic action appears to involve the inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons.",507.58,"1316755-16-4",{"v":100,"d":"100.00"},197.01,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/ema401.html","C32H29NO5","Free Base","PD-126055, (S) PD-126055","COC1=C(OCC2=CC=CC=C2)C3=C(CN(C(C3)C(O)=O)C(=O)C(C4=CC=CC=C4)C5=CC=CC=C5)C=C1",5.599,4,0,8]
["S0446","TCN 201","f7","L4000-18","in 10mM DMSO","NMDAR","Neuronal Signaling","TCN-201 is  a selective GluN1/GluN2A (NR1/NR2A) NMDA receptor antagonist with pIC50 6.8 for NR1/NR2A and <4.3 for NR1/NR2B (GluN1/GluN2B),respectively.",461.89,"852918-02-6",{"v":92,"d":"92.00"},199.18,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/tcn-201.html","C21H17ClFN3O4S","Free Base","N/A","FC1=C(Cl)C=C(C=C1)[S](=O)(=O)NCC2=CC=C(C=C2)C(=O)NNC(=O)C3=CC=CC=C3",3.236,4,3,7]
["S0838","S-(4-Nitrobenzyl)-6-thioinosine (NBMPR)","g7","L4000-18","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","S-(4-Nitrobenzyl)-6-thioinosine (NBMPR, Nitrobenzylthioinosine, NBTI, NSC 296962) is an inhibitor of ENT1 transporter that crosses the blood-brain barrier and is able to potentiate the neuroprotective effects of adenosine.",419.41,"38048-32-7",{"v":84,"d":"84.00"},200.28,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/nbmpr.html","C17H17N5O6S","Free Base","Nitrobenzylthioinosine, NBTI, NSC 296962","OCC1OC(C(O)C1O)[N]2C=NC3=C2N=CN=C3SCC4=CC=C(C=C4)[N+]([O-])=O",0.885,4,3,6]
["S4485","Olodaterol (BI 1744)","h7","L4000-18","in 10mM DMSO","Adrenergic Receptor","Endocrinology & Hormones","Olodaterol (BI 1744) is a long-acting β2-adrenergic receptor agonist that is used as a component of an inhalation (Tiotropium/Olodaterol) for treating patients with chronic obstructive pulmonary disease (COPD).",386.44,"868049-49-4",{"v":77,"d":"77.00"},199.25,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/olodaterol-bi-1744-.html","C21H26N2O5","Free Base","N/A","COC1=CC=C(CC(C)(C)NCC(O)C2=C3OCC(=O)NC3=CC(=C2)O)C=C1",1.875,3,4,7]
["S5980","Losartan Carboxylic Acid (EXP-3174)","a8","L4000-18","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Losartan Carboxylic Acid (E-3174, EXP-3174), an active carboxylic acid metabolite of Losartan, is a non-peptide angiotensin II (AT1) receptor antagonist. Losartan Carboxylic Acid inhibits the specific binding of [125I]-angiotensin II to VSMC with IC50 of 1.1 nM.",436.89,"124750-92-1",{"v":87,"d":"87.00"},199.13,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/losartan-carboxylic-acid-exp-3174-.html","C22H21ClN6O2","Free Base","E-3174","CCCCC1=NC(=C([N]1CC2=CC=C(C=C2)C3=CC=CC=C3C4=N[NH]N=N4)C(O)=O)Cl",5.129,5,1,8]
["S6301","MPP+ iodide","b8","L4000-18","in 10mM DMSO","Autophagy,Dopamine Receptor,Serotonin Transporter","Autophagy","MPP+ iodide (N-Methyl-4-Phenylpyridinium Iodide), the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces autophagic cell death in SH-SY5Y cells. MPP+ induces dopamine transporter (DAT) externalization in dopaminergic (DA) neurons, but internalization of serotonin transporter (SERT) in serotonergic (5-HT) neurons.",297.13,"36913-39-0",{"v":72,"d":"72.00"},242.32,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/mpp-iodide.html","C12H12IN","Iodide","N-Methyl-4-Phenylpyridinium Iodide","[I-].C[N+]1=CC=C(C=C1)C2=CC=CC=C2",{"v":-0.16,"d":"-0.160"},0,0,1]
["S6347","5'-N-Ethylcarboxamidoadenosine (NECA)","c8","L4000-18","in 10mM DMSO","Adenosine Receptor,CD markers,Interleukins,JNK,p38 MAPK,TNF-alpha","GPCR & G Protein","5'-N-Ethylcarboxamidoadenosine (NECA, 5'-(N-Ethylcarboxamido)adenosine, Adenosine-5'N-ethylcarboxamide, 5'-Ethylcarboxamidoadenosine) is a stable, nonselective adenosine receptor agonist. 5'-N-Ethylcarboxamidoadenosine acts via multiple mechanisms including: reducing diabetes-induced oxidative stress, inhibiting gene expression of IL-18, TNF-α and ICAM-1 (intercellular adhesion molecule 1 (CD54)), and blocking activation of the JNK-MAPK pathway.",308.29,"35920-39-9",{"v":62,"d":"62.00"},201.11,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/5-n-ethylcarboxamidoadenosine.html","C12H16N6O4","Free Base","5'-(N-Ethylcarboxamido)adenosine, Adenosine-5'N-ethylcarboxamide, 5'-Ethylcarboxamidoadenosine","CCNC(=O)C1OC(C(O)C1O)[N]2C=NC3=C(N)N=CN=C23",-1.826,5,4,3]
["S6947","MK6-83","d8","L4000-18","in 10mM DMSO","TRP Channel","Transmembrane Transporters","MK6-83 is a novel Transient receptor potential melastatin member 1 (TRPML1) activator that may be used as a potential pharmacological treatment option for a specific subgroup of MLIV patients.",336.47,"1062271-24-2",{"v":67,"d":"67.00"},199.13,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/mk6-83.html","C16H20N2O2S2","Free Base","N/A","CC1=CC=C(S1)[S](=O)(=O)NC2=CC=CC=C2N3CCCCC3",3.329,2,1,4]
["S6981","Glycerol phenylbutyrate","e8","L4000-18","in 10mM DMSO","Sigma Receptor","GPCR & G Protein","Glycerol phenylbutyrate (GT4P, HPN-100M, Ravicti) is a nitrogen-binding agent and acts as a sigma-2 (σ2) receptor ligand with a pKi of 8.02. Glycerol phenylbutyrate is a prodrug in which phenylbutyrate (PBA) is released from the glycerol backbone by lipases in the gastrointestinal tract.",530.65,"611168-24-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/glycerol-phenylbutyrate.html","C33H38O6","Free Base","GT4P, HPN-100M, Ravicti","O=C(CCCC1=CC=CC=C1)OCC(COC(=O)CCCC2=CC=CC=C2)OC(=O)CCCC3=CC=CC=C3",7.563,6,0,20]
["S6985","Varenicline","f8","L4000-18","in 10mM DMSO","AChR","Neuronal Signaling","Varenicline(CP 526555) is highly selective and blocks more potently to α4β2 receptors than to other common nicotinic receptors (>500-fold α3β4, >3,500-fold α7, >20,000-fold α1βγδ), or to non-nicotinic receptors and transporters (>2,000-fold). Varenicline also acts as an agonist of 5-HT3 serotonine receptors.",211.26,"249296-44-4",{"v":42,"d":"42.00"},198.81,{"v":3,"d":"3.00"},{"v":14.2,"d":"14.20"},"http://www.selleckchem.com/products/varenicline.html","C13H13N3","Free Base","Chantix, Champix,CP 526555","C1NCC2CC1C3=CC4=NC=CN=C4C=C23",1.038,2,1,0]
["S7538","RS-102895 Hydrochloride","g8","L4000-18","in 10mM DMSO","5-HT Receptor,Adrenergic Receptor,CCR","GPCR & G Protein","RS-102895 hydrochloride (HCl) is a potent antagonist of Chemokine (C-C motif) receptor 2 (CCR2) with IC50 of 360 nM, and shows no effect on CCR1. RS-102895 hydrochloride also inhibits human α1a and α1d receptors, rat brain cortex 5-HT1a receptor in cells with IC50s of 130 nM, 320 nM, 470 nM, respectively.",426.86,"1173022-16-6",{"v":85,"d":"85.00"},199.13,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/rs-102895-hydrochloride.html","C21H22ClF3N2O2","Hydrochloride","RS-102895 HCl","Cl.FC(F)(F)C1=CC=C(CCN2CCC3(CC2)OC(=O)NC4=CC=CC=C34)C=C1",4.543,2,1,4]
["S7848","QX-314 chloride","h8","L4000-18","in 10mM DMSO","Sodium Channel,TRP Channel","Transmembrane Transporters","QX-314 chloride directly activates and permeates the human isoforms of TRPV1 and TRPA1 to induce inhibition of sodium channels.",298.85,"5369-03-9",{"v":60,"d":"60.00"},200.77,{"v":60,"d":"60.00"},200.77,"http://www.selleckchem.com/products/qx-314-chloride.html","C16H27ClN2O","Chloride","N/A","[Cl-].CC[N+](CC)(CC)CC(=O)NC1=C(C)C=CC=C1C",-1.054,1,1,6]
["S9842","MCU-i4","a9","L4000-18","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","MCU-i4 is a negative modulator of the mitochondrial calcium uniporter (MCU) complex that directly binds a specific cleft in MICU1 and decreases mitochondrial Ca2+ influx.",377.48,"371924-24-2",{"v":10,"d":"10.00"},26.49,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/mcu-i4.html","C23H27N3O2","Free Base","N/A","CCOC(=O)C1=C(NC2=CC=C(C=C2)N(CC)CC)C3=C(C=CC(=C3)C)N=C1",5.116,3,1,8]
["S9886","Biocytin","b9","L4000-18","in 10mM DMSO","Dyes","Others","Biocytin ((+)-Biocytin, Biotinyl-L-lysine) is a conjugate of D-biotin and L-lysine. Biocytin is an attractive neuronal tracer. It labels neurons fast over long distances, and it can be used in conjunction with calcium dyes to report on neuronal activity in retrogradely labeled live neurons.",372.48,"576-19-2",{"v":75,"d":"75.00"},201.35,{"v":75,"d":"75.00"},201.35,"http://www.selleckchem.com/products/biocytin.html","C16H28N4O4S","Free Base","(+)-Biocytin, Biotinyl-L-lysine","NC(CCCCNC(=O)CCCCC1SCC2NC(=O)NC12)C(O)=O",-2.344,3,4,11]
["E0009","Harmane","c9","L4000-18","in 10mM DMSO","MAO","Neuronal Signaling","Harmane (Harman, Aribine, Aribin, Locuturine, Locuturin, Loturine, Passiflorin, 1-Methylnorharman, NSC 54439) is a common compound in several foods, plants and beverages. Harmane is a selective monoamine oxidase inhibitors with IC50s of 0.5 μM and 5 μM for human MAO A and MAO B, respectively. Harmane also inhibits the apurinic/apyrimidinic (AP) endonuclease activity of the UV endonuclease induced by phage T4.",182.22,"486-84-0",{"v":36,"d":"36.00"},197.56,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/harmane.html","C12H10N2","Free Base","Harman, Aribine, Aribin, Locuturine, Locuturin, Loturine, Passiflorin, 1-Methylnorharman, NSC 54439","CC1=NC=CC2=C1[NH]C3=CC=CC=C23",2.455,1,1,0]
["E0020","Lupenone","d9","L4000-18","in 10mM DMSO","Akt,Apoptosis related,Immunology & Inflammation related,PI3K","Immunology & Inflammation","Lupenone (Lup-20(29)-en-3-one, lupeone) is an isolated compound exhibiting anti-oxidative, anti-inflammation, and anti-diabetic activities. Lupenone can protect SH-SY5y cells against METH-induced neuronal apoptosis through the PI3K/Akt pathway.",{"v":424.7,"d":"424.70"},"1617-70-5",{"v":5,"d":"5.00"},11.77,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/lupenone.html","C30H48O","Free Base","Lup-20(29)-en-3-one, lupeone","CC(=C)C1CCC2(C)CCC3(C)C(CCC4C5(C)CCC(=O)C(C)(C)C5CCC34C)C12",7.503,1,0,1]
["E0028","9-Phenanthrol","e9","L4000-18","in 10mM DMSO","TRP Channel","Transmembrane Transporters","9-Phenanthrol (9-Hydroxyphenanthrene, Phenanthren-9-o, 9-Phenanthrenol) is a selective TRPM4 inhibitor with an IC50 in the range of 0.02 μM, without effects on TRPM5.",194.23,"484-17-3",{"v":39,"d":"39.00"},200.79,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/9-phenanthrol.html","C14H10O","Free Base","9-Hydroxyphenanthrene, Phenanthren-9-ol, 9-Phenanthrenol","OC1=CC2=CC=CC=C2C3=CC=CC=C13",3.404,0,1,0]
["S0019","JNJ-10229570","f9","L4000-18","in 10mM DMSO","Melanocortin Receptor","GPCR & G Protein","JNJ-10229570 (UNII-N9IX402L35) is a potent MC1R and MC5R antagonist.",389.47,"524923-88-4",{"v":78,"d":"78.00"},200.27,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/jnj-10229570.html","C22H19N3O2S","Free Base","UNII-N9IX402L35","COC1=CC=CC=C1N2SC(=NC3=CC=CC=C3)N=C2C4=CC=CC=C4OC",{"v":5.67,"d":"5.670"},4,0,5]
["S0529","PBD-150","g9","L4000-18","in 10mM DMSO","Beta Amyloid","Neuronal Signaling","PBD-150 is a potent human glutaminyl cyclase (hQC) Y115E-Y117E variant inhibitor with Ki of 60 nM.",320.41,"790663-33-1",{"v":64,"d":"64.00"},199.74,"<1","N/A","http://www.selleckchem.com/products/pbd-150.html","C15H20N4O2S","Free Base","N/A","COC1=C(OC)C=C(NC(=S)NCCC[N]2C=CN=C2)C=C1",{"v":2.28,"d":"2.280"},3,2,9]
["S0720","PNU-282987","h9","L4000-18","in 10mM DMSO","AChR","Neuronal Signaling","PNU-282987 is a novel selective agonist of the alpha7 nAChR with Ki of 26 nM for rat alpha7 nAChR. PNU-282987 shows no activity at all tested monoamine, muscarine, glutamate, and GABA receptors, except 5-HT3 receptors with Ki of 930 nM.",264.75,"711085-63-1",{"v":53,"d":"53.00"},200.19,"<1","N/A","http://www.selleckchem.com/products/pnu-282987-.html","C14H17ClN2O","Free Base","N/A","ClC1=CC=C(C=C1)C(=O)NC2CN3CCC2CC3",{"v":2.24,"d":"2.240"},1,1,2]
["S0897","Cyclizine","a10","L4000-18","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Cyclizine is a piperazine first-generation antagonist of histamine 1 receptor.",266.38,"82-92-8",{"v":53,"d":"53.00"},198.96,"<1","N/A","http://www.selleckchem.com/products/cyclizine.html","C18H22N2","Free Base","N/A","CN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3",{"v":3.47,"d":"3.470"},0,0,3]
["S1335","VX-150","b10","L4000-18","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","VX-150 (EOS-62073) is an orally bioavailable pro-drug that rapidly converts into its active moiety, which is a highly selective inhibitor of NaV1.8 relative to the other sodium channel subtypes (>400-fold).",516.34,"1793080-72-4",{"v":100,"d":"100.00"},193.67,"<1","N/A","http://www.selleckchem.com/products/vx-150.html","C21H17F4N2O7P","Free Base","EOS-62073","CC1=C(OC2=C(C=CC(=C2)C(F)(F)F)C(=O)NC3=CC(=O)N(CO[P](O)(O)=O)C=C3)C=CC(=C1)F",{"v":2.94,"d":"2.940"},4,1,8]
["S2963","WS-12","c10","L4000-18","in 10mM DMSO","TRP Channel","Transmembrane Transporters","WS-12 is a potent TRPM8 agonist with an EC50 of 39 nM.",289.41,"68489-09-8",{"v":58,"d":"58.00"},200.41,"<1","N/A","http://www.selleckchem.com/products/ws-12.html","C18H27NO2","Free Base","N/A","COC1=CC=C(NC(=O)C2CC(C)CCC2C(C)C)C=C1",{"v":4.27,"d":"4.270"},2,1,4]
["S3584","Luzindole","d10","L4000-18","in 10mM DMSO","MT Receptor","GPCR & G Protein","Luzindole (N-0774, N-acetyl-2-benzyltryptamine) is a selective melatonin receptor antagonist with Kis of 179 nM for MT1 and 7.3 nM for MT2, respectively.",292.37,"117946-91-5",{"v":58,"d":"58.00"},198.38,"<1","N/A","http://www.selleckchem.com/products/luzindole.html","C19H20N2O","Free Base","N-0774","CC(=O)NCCC1=C(CC2=CC=CC=C2)[NH]C3=CC=CC=C13",{"v":3.42,"d":"3.420"},1,2,5]
["S6070","CBA (TRPM4-IN-5)","e10","L4000-18","in 10mM DMSO","TRP Channel","Transmembrane Transporters","CBA (TRPM4-IN-5, Compound 5) is a highly selective blocker of the TRPM4 ion channel with an IC50 of 1.5μM.",340.16,"351424-20-9",{"v":68,"d":"68.00"},199.91,"<1","N/A","http://www.selleckchem.com/products/cba-trpm4-in-1.html","C15H11Cl2NO4","Free Base","Compound 5, TRPM4 inhibitor 5","OC(=O)C1=C(NC(=O)COC2=CC=CC=C2Cl)C=C(Cl)C=C1",{"v":3.41,"d":"3.410"},3,1,5]
["S6694","Grapiprant (CJ-023,423)","f10","L4000-18","in 10mM DMSO","Prostaglandin Receptor","GPCR & G Protein","Grapiprant (CJ-023,423, AT-001, AAT-007, RQ-00000007, CJ-23423) is a novel selective EP4 Prostaglandin Receptor inhibitor with Ki of 20 nM and 13 nM for rat EP4 receptor and human EP4 receptor, respectively.",491.61,"415903-37-6",{"v":98,"d":"98.00"},199.35,"<1","N/A","http://www.selleckchem.com/products/grapiprant-cj-023423.html","C26H29N5O3S","Free Base","AT-001, AAT-007, RQ-00000007, CJ-23423","CCC1=NC2=C(C=C(C)N=C2C)[N]1C3=CC=C(CCNC(=O)N[S](=O)(=O)C4=CC=C(C)C=C4)C=C3",{"v":4.55,"d":"4.550"},5,2,7]
["S9498","5-BDBD","g10","L4000-18","in 10mM DMSO","P2 Receptor","Neuronal Signaling","5-BDBD is a potent P2X4R selective antagonist with an IC50 of 0.75 μM when applied for 2 min prior and during ATP stimulation.",355.19,"768404-03-1",{"v":71,"d":"71.00"},199.89,"<1","N/A","http://www.selleckchem.com/products/5-bdbd.html","C17H11BrN2O2","Free Base","N/A","BrC1=CC=CC(=C1)C2=NCC(=O)NC3=C2OC4=CC=CC=C34",{"v":3.64,"d":"3.640"},3,1,1]
["S9926","ML-SA1","h10","L4000-18","in 10mM DMSO","Antiviral,TRP Channel","Transmembrane Transporters","ML-SA1 (Mucolipin synthetic agonist 1) is an activator of TRPML channels. ML-SA1 also inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 values of ML-SA1 against DENV2 RNA and ZIKV RNA are 8.93 μM and 52.99 μM, respectively. ML-SA1 induces autophagy. ML-SA1 can be used for the research of broad-spectrum antiviral.",362.42,"332382-54-4",{"v":18,"d":"18.00"},49.67,"<1","N/A","http://www.selleckchem.com/products/ml-sa1.html","C22H22N2O3","Free Base","Mucolipin synthetic agonist 1","CC1CC(C)(C)N(C(=O)CN2C(=O)C3=C(C=CC=C3)C2=O)C4=C1C=CC=C4",{"v":3.07,"d":"3.070"},3,0,2]
["E0026","ML-SI3","a11","L4000-18","in 10mM DMSO","TRP Channel","Transmembrane Transporters","ML-SI3 is a potent TRPML channel inhibitor with IC50s of 4.7 &micro;M and 1.7 &micro;M for TRPML1 and TRPML2, respectively.",429.58,"891016-02-7",{"v":43,"d":"43.00"},{"v":100.1,"d":"100.10"},"<1","N/A","http://www.selleckchem.com/products/ml-si3.html","C23H31N3O3S","Free Base","N/A","COC1=CC=CC=C1N2CCN(CC2)C3CCCCC3N[S](=O)(=O)C4=CC=CC=C4",{"v":3.92,"d":"3.920"},3,1,6]
["E0031","RN-1747","b11","L4000-18","in 10mM DMSO","TRP Channel","Transmembrane Transporters","RN-1747 is a selective TRPV4 agonist with EC50s of 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4, respectively. RN-1747 also antagonizes TRPM8 with IC50 of 4 μM.",395.86,"1024448-59-6",{"v":79,"d":"79.00"},199.57,"<1","N/A","http://www.selleckchem.com/products/rn-1747.html","C17H18ClN3O4S","Free Base","N/A","[O-][N+](=O)C1=C(C=CC(=C1)Cl)[S](=O)(=O)N2CCN(CC2)CC3=CC=CC=C3",{"v":3.05,"d":"3.050"},2,0,5]
["E0076","Simufilam dihydrochloride","c11","L4000-18","in 10mM DMSO","Actin","Cytoskeletal Signaling","Simufilam (PTI-125) Dihydrochloride is a small molecule modulator that preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7nAChR/TLR4 associations and downstream pathologies.",332.27,"2480226-06-8",{"v":66,"d":"66.00"},198.63,{"v":66,"d":"66.00"},198.63,"http://www.selleckchem.com/products/simufilam-dihydrochloride.html","C15H23Cl2N3O","Dihydrochloride","PTI-125 dihydrochloride","Cl.Cl.CN1CCC2(CC1)NCC(=O)N2CC3=CC=CC=C3",{"v":1.86,"d":"1.860"},1,1,2]
["E0137","GV-58","d11","L4000-18","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","GV-58 is a novel, selective N-type and P/Q-type Ca2+ channels agonist with IC50s of 7.21 μM and 8.81 μM, respectively.",{"v":374.5,"d":"374.50"},"1402821-41-3",{"v":75,"d":"75.00"},200.27,"<1","N/A","http://www.selleckchem.com/products/gv-58.html","C18H26N6OS","Free Base","N/A","CCC[N]1C=NC2=C(NCC3=CC=C(C)S3)N=C(NC(CC)CO)N=C12",{"v":3.35,"d":"3.350"},3,3,9]
["E0165","Phenelzine sulfate","e11","L4000-18","in 10mM DMSO","MAO","Neuronal Signaling","Phenelzine Sulfate is a hydrazine derivative and acts as a potent non-selective monoamine oxidase (MAO) inhibitor with an IC50 of 0.9 μM.",234.27,"156-51-4",{"v":47,"d":"47.00"},200.62,{"v":47,"d":"47.00"},200.62,"http://www.selleckchem.com/products/phenelzine-sulfate.html","C8H12N2.H2O4S","Sulfate","N/A","NNCCC1=CC=CC=C1.O[S](O)(=O)=O",{"v":0.31,"d":"0.310"},0,2,3]
["E0172","Imidacloprid","f11","L4000-18","in 10mM DMSO","AChR","Neuronal Signaling","Imidacloprid is a nicotinic acetylcholine receptor (nAChR) agonist with potent insecticidal activity.",255.66,"138261-41-3",{"v":51,"d":"51.00"},199.48,"<1","N/A","http://www.selleckchem.com/products/imidacloprid.html","C9H10ClN5O2","Free Base","N/A","[O-][N+](=O)\\N=C1/NCCN1CC2=CC=C(Cl)N=C2",{"v":3.7,"d":"3.700"},2,1,3]
["E0176","Dinotefuran","g11","L4000-18","in 10mM DMSO","AChR","Neuronal Signaling","Dinotefuran (MTI-446), a neonicotinoid, is an effective nAChRs agonist with EC50 of 7.8 μM and shows high insecticidal activity on Da2b2 hybrid nAChRs.",202.21,"165252-70-0",{"v":40,"d":"40.00"},197.81,{"v":40,"d":"40.00"},197.81,"http://www.selleckchem.com/products/dinotefuran.html","C7H14N4O3","Free Base","MTI-446","CNC(N[N+]([O-])=O)=NCC1CCOC1",{"v":1.6,"d":"1.600"},2,2,5]
["E0356","MIPS521","h11","L4000-18","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","MIPS521 is a positive allosteric modulator of the A1R that exhibits analgesic efficacy in rats in vivo.",{"v":449.8,"d":"449.80"},"1146188-19-3",{"v":90,"d":"90.00"},200.09,"<1","N/A","http://www.selleckchem.com/products/mips521.html","C19H10ClF6NOS","Free Base","N/A","NC1=C(C(=O)C2=CC=C(Cl)C=C2)C(=CS1)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F",{"v":6.34,"d":"6.340"},1,1,5]
["E1002","Setmelanotide (RM-493)","a2","L4000-19","in 10mM DMSO","Melanocortin Receptor","GPCR & G Protein","Setmelanotide (RM-493, BIM-22493, CAM 4072) is a cyclic peptide full agonist of melanocortin-4 receptor (MC4R) with an EC50 of 0.27 nM and a Ki of 2.1 nM.",1117.31,"920014-72-8",{"v":100,"d":"100.00"},{"v":89.5,"d":"89.50"},{"v":100,"d":"100.00"},{"v":89.5,"d":"89.50"},"http://www.selleckchem.com/products/setmelanotide-rm-493.html","C49H68N18O9S2","Free Base","BIM-22493, CAM 4072","CC1NC(=O)C(CSSCC(NC(=O)C(CC2=C[NH]C3=CC=CC=C23)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CN=C[NH]5)NC1=O)C(N)=O)NC(=O)C(CCCN=C(N)N)NC(C)=O",{"v":-2.64,"d":"-2.640"},12,15,18]
["P1211","Apelin-13","b2","L4000-19","in 10mM DMSO","GPR","GPCR & G Protein","Apelin-13 can efficiently antagonize the APJ receptor with EC50 of 0.37 nM and result in suppress the forskolin-stimulated cAMP production.",1550.83,"217082-58-1",{"v":100,"d":"100.00"},64.48,{"v":100,"d":"100.00"},64.48,"http://www.selleckchem.com/products/apelin-13.html","C69H111N23O16S","Free Base","N/A","CSCCC(NC(=O)C1CCCN1C(=O)CNC(=O)C(CCCCN)NC(=O)C(CC2=C[NH]C=N2)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(N)=N)NC(=O)C3CCCN3C(=O)C(CCCNC(N)=N)NC(=O)C(N)CCC(N)=O)C(=O)N4CCCC4C(=O)NC(CC5=CC=CC=C5)C(O)=O",{"v":-8.7,"d":"-8.700"},15,18,49]
["P1212","(Ala13)-Apelin-13","c2","L4000-19","in 10mM DMSO","GPR","GPCR & G Protein","(Ala13)-Apelin-13 is a potent APJ receptor antagonist and can prevent the apelin-induced reduction in gastric tone and motility.",1474.73,"568565-11-7",{"v":100,"d":"100.00"},67.81,{"v":100,"d":"100.00"},67.81,"http://www.selleckchem.com/products/ala13-apelin-13.html","C63H107N23O16S","Free Base","N/A","CSCCC(NC(=O)C1CCCN1C(=O)CNC(=O)C(CCCCN)NC(=O)C(CC2=C[NH]C=N2)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(N)=N)NC(=O)C3CCCN3C(=O)C(CCCNC(N)=N)NC(=O)C(N)CCC(N)=O)C(=O)N4CCCC4C(=O)NC(C)C(O)=O",{"v":-10.25,"d":"-10.250"},15,18,47]
["S0007","RO 5028442 (RG7713)","d2","L4000-19","in 10mM DMSO","Vasopressin Receptor","GPCR & G Protein","RO 5028442 (RG7713) is a highly potent and selective Brain-Penetrant Vasopressin 1a (V1a) receptor antagonist with Kis of 1 nM for hV1a and 39 nM for mV1a.",437.96,"920022-47-5",{"v":5,"d":"5.00"},11.42,"<1","N/A","http://www.selleckchem.com/products/ro-5028442-rg7713.html","C25H28ClN3O2","free base","N/A","CN(C)CC[N]1C=C(C(=O)N2CCC3(CC2)OCC4=C3C=CC=C4)C5=C1C=C(Cl)C=C5",{"v":3.58,"d":"3.580"},2,0,4]
["S0009","Asimadoline hydrochloride","e2","L4000-19","in 10mM DMSO","Opioid Receptor","GPCR & G Protein","Asimadoline hydrochloride (EMD-61753 hydrochloride) is an orally active, selective and peripherally active κ-opioid agonist with IC50s of 5.6 nM (guinea pig) and 1.2 nM (human recombinant).",{"v":451,"d":"451.00"},"185951-07-9",{"v":90,"d":"90.00"},199.56,{"v":3,"d":"3.00"},6.65,"http://www.selleckchem.com/products/asimadoline.html","C27H30N2O2.ClH","hydrochloride","EMD-61753 hydrochloride","Cl.CN(C(CN1CCC(O)C1)C2=CC=CC=C2)C(=O)C(C3=CC=CC=C3)C4=CC=CC=C4",4.276,1,1,7]
["S0017","Lu-135252","f2","L4000-19","in 10mM DMSO","Endothelin Receptor","GPCR & G Protein","Lu-135252 (Darusentan,HMR-4005) is a selective endothelin A receptor (ET-A receptor) antagonist indicated for the oral treatment of resistant hypertension.",410.42,"171714-84-4",{"v":82,"d":"82.00"},{"v":199.8,"d":"199.80"},"<1","N/A","http://www.selleckchem.com/products/lu-135252.html","C22H22N2O6","free base","Darusentan, HMR-4005","COC1=NC(=NC(=C1)OC)OC(C(O)=O)C(OC)(C2=CC=CC=C2)C3=CC=CC=C3",4.139,7,0,9]
["S0073","BI 01383298","g2","L4000-19","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","BI 01383298 is an irreversible and non-competitive inhibitor of human sodium-coupled citrate transporter (hNaCT), in which the inhibition is evident for the constitutively expressed transporter in HepG2 cells and for the ectopically expressed human NaCT in HEK293 cells, with IC50 of ~100 nM.",445.34,"2227549-00-8",{"v":45,"d":"45.00"},101.05,"<1","N/A","http://www.selleckchem.com/products/bi-01383298.html","C19H19Cl2FN2O3S","free base","N/A","FC1=CC=C(CNC(=O)C2CCN(CC2)[S;v6](=O)(=O)C3=CC(=CC(=C3)Cl)Cl)C=C1",3.744,3,1,5]
["S0080","SNAP94847 hydrochloride","h2","L4000-19","in 10mM DMSO","GPR","GPCR & G Protein","SNAP 94847 hydrochloride is a high affinity and selective antagonist of the MCH1 receptor with an IC50 of 230 nM for rat MCH1 in FLIPR calcium mobility assay.",{"v":515,"d":"515.00"},"1781934-47-1",{"v":96,"d":"96.00"},{"v":200.6,"d":"200.60"},"<1","N/A","http://www.selleckchem.com/products/snap94847.html","C29H33ClF2N2O2","hydrochloride","SNAP 94847 hydrochloride","Cl.CC(C)C(=O)NC1=CC(=C(C)C=C1)C2CCN(CC2)CC3=CC=C(OC4=CC(=C(F)C=C4)F)C=C3",7.194,2,1,7]
["S0111","Taprenepag","a3","L4000-19","in 10mM DMSO","Prostaglandin Receptor","Immunology & Inflammation","Taprenepag(CP-544326) is a potent and selective prostaglandin EP2 agonist with IC50s of 10 and 15 nM for human and rat EP2, respectively.",478.52,"752187-80-7",{"v":96,"d":"96.00"},200.62,"<1","N/A","http://www.selleckchem.com/products/cp544326.html","C24H22N4O5S","free base","CP-544326","OC(=O)COC1=CC=CC(=C1)CN(CC2=CC=C(C=C2)[N]3C=CC=N3)[S;v6](=O)(=O)C4=CN=CC=C4",2.655,6,0,10]
["S0282","YL 0919","b3","L4000-19","in 10mM DMSO","5-HT Receptor,5-HT Receptor","Neuronal Signaling","YL0919, a novel structure compound, exerts dual effect on the serotonergic system, as both 5-hydroxytryptamine receptor 1A (5-HT1A) agonist and 5-HT uptake blocker, showing remarkable antidepressant effects in animal models.",334.84,"1339058-04-6",{"v":67,"d":"67.00"},{"v":200.1,"d":"200.10"},"<1","N/A","http://www.selleckchem.com/products/yl-0919.html","C18H22N2O2.ClH","hydrochloride","N/A","Cl.OC1(CCN(CC1)CC2=CC=CC=C2)CN3C=CC=CC3=O",1.275,1,0,4]
["S0318","Ansofaxine hydrochloride","c3","L4000-19","in 10mM DMSO","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Ansofaxine hydrochloride (LY03005, LPM570065), a triple reuptake inhibitor, inhibits serotonin, dopamine and norepinephrine reuptake with IC50 values of 723, 491 and 763 nM, respectively.",417.97,"916918-84-8",{"v":84,"d":"84.00"},200.97,{"v":3,"d":"3.00"},7.18,"http://www.selleckchem.com/products/ansofaxine-hydrochloride.html","C24H31NO3.ClH","hydrochloride","LY03005, LPM570065","Cl.CN(C)CC(C1=CC=C(OC(=O)C2=CC=C(C)C=C2)C=C1)C3(O)CCCCC3",5.338,2,0,7]
["S0319","D3-βArr","d3","L4000-19","in 10mM DMSO","TSH Receptor","Endocrinology & Hormones","D3-βArr(NCGC00379308) is a positive allosteric modulator of thyrotropin receptor (TSHR) that modulates TSH-induced β-Arr 1 translocation.",333.43,"662164-09-2",{"v":67,"d":"67.00"},200.94,"<1","N/A","http://www.selleckchem.com/products/d3-betaarr.html","C20H23N5","free base","NCGC00379308","CC(NC1=C2C=CC=CC2=NC(=N1)N3CCNCC3)C4=CC=CC=C4",3.801,2,2,4]
["S0452","NP118809","e3","L4000-19","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","NP118809(39-1B4) is a potent N-type calcium channel blocker, with an IC50 of 0.11 μM, also less potently inhibits L-type calcium channel with an IC50 of 12.2 μM.",460.61,"41332-24-5",{"v":92,"d":"92.00"},199.74,"<1","N/A","http://www.selleckchem.com/products/np118809.html","C32H32N2O","free base","39-1B4","O=C(CC(C1=CC=CC=C1)C2=CC=CC=C2)N3CCN(CC3)C(C4=CC=CC=C4)C5=CC=CC=C5",6.172,1,0,7]
["S0518","NS 1738","f3","L4000-19","in 10mM DMSO","AChR","GPCR & G Protein","NS 1738 (NSC 213859) is a novel positive allosteric modulator of the α7 nicotinic acetylcholine receptor (α7 nAChR), with respect to positive modulation of Xenopus laevis oocyte α7 nAChR with EC50 of 3.4 μM, as well as a comparable efficacy at the rat α7 nAChR with EC50 of 3.9 μM.",365.13,"501684-93-1",{"v":73,"d":"73.00"},199.93,"<1","N/A","http://www.selleckchem.com/products/ns-1738.html","C14H9Cl2F3N2O2","free base","NSC 213859","OC1=CC=C(Cl)C=C1NC(=O)NC2=CC(=CC=C2Cl)C(F)(F)F",4.552,1,3,3]
["S0521","PNU-282987 S enantiomer free base","g3","L4000-19","in 10mM DMSO","AChR","Neuronal Signaling","PNU-282987 S enantiomer free base is the S-enantiomer of PNU-282987 free base, which is an α7 nicotinic acetylcholine receptor (α7 nAChR) agonist.",264.75,"737727-12-7",{"v":53,"d":"53.00"},200.19,"<1","N/A","http://www.selleckchem.com/products/pnu-282987-s-enantiomer-free-base.html","C14H17ClN2O","free base","N/A","ClC1=CC=C(C=C1)C(=O)NC2CN3CCC2CC3",2.238,1,1,2]
["S0535","FK962","h3","L4000-19","in 10mM DMSO","Calcium Channel,SSTR","Transmembrane Transporters","FK962, a derivative of FK960 with putative anti-dementia properties, significantly enhances high K+-evoked somatostatin release from rat hippocampal slices at 1-1000 nM, also significantly reduces somatostatin-induced inhibition of Ca2+ channels at 1-100 nM in single rat hippocampal neurons.",{"v":264.3,"d":"264.30"},"283167-06-6",{"v":53,"d":"53.00"},200.53,{"v":2,"d":"2.00"},7.57,"http://www.selleckchem.com/products/fk962.html","C14H17FN2O2","free base","N/A","CC(=O)N1CCC(CC1)NC(=O)C2=CC=C(F)C=C2",0.613,2,1,2]
["S0762","SC 236","a4","L4000-19","in 10mM DMSO","COX","Immunology & Inflammation","SC-236 is a potent, selective, orally active inhibitor of COX-2 with an IC50 of 10 nM and approximately 18,000-fold COX-2 selectivity.",401.79,"170569-86-5",{"v":80,"d":"80.00"},199.11,"<1","N/A","http://www.selleckchem.com/products/sc-236.html","C16H11ClF3N3O2S","free base","N/A","N[S](=O)(=O)C1=CC=C(C=C1)[N]2N=C(C=C2C3=CC=C(Cl)C=C3)C(F)(F)F",4.606,3,1,4]
["S0893","SB-200646A","b4","L4000-19","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","SB-200646A is the first selective 5-HT2B/2C over 5-HT2A receptor antagonist with pKi values of 7.5, 6.9 and 5.2 for 5-HT2B, 5-HT2C and 5-HT2A, respectively.",302.76,"143797-62-0",{"v":100,"d":"100.00"},330.29,{"v":3,"d":"3.00"},9.91,"http://www.selleckchem.com/products/sb-200646a.html","C15H14N4O.ClH","hydrochloride","N/A","Cl.C[N]1C=CC2=CC(=CC=C12)NC(=O)NC3=CC=CN=C3",2.253,2,2,2]
["S0896","DSP-4 HCl","c4","L4000-19","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","DSP-4 hydrochloride (Neurotoxin DSP 4 (hydrochloride)) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, which exclusively affects the noradrenergic fibers from the LC (locus coeruleus).",313.06,"40616-75-9",{"v":83,"d":"83.00"},200.91,{"v":83,"d":"83.00"},200.91,"http://www.selleckchem.com/products/dsp-4-hcl.html","C11H15BrClN.ClH","hydrochloride","Neurotoxin DSP 4 (hydrochloride)","Cl.CCN(CCCl)CC1=C(Br)C=CC=C1",4.048,0,0,5]
["S1970","VU-29","d4","L4000-19","in 10mM DMSO","GluR","Metabolism","VU-29 is a positive allosteric modulator of metabotropic glutamate 5 (mGlu5) receptor, with EC50 of 9 nM and Ki=244 nM for rat mGluR5, which is selective for mGluR5 relative to other mGluR subtypes.",384.39,"890764-36-0",{"v":77,"d":"77.00"},200.32,"<1","N/A","http://www.selleckchem.com/products/vu-29.html","C22H16N4O3","free base","N/A","[O-][N+](=O)C1=CC=C(C=C1)C(=O)NC2=CC(=N[N]2C3=CC=CC=C3)C4=CC=CC=C4",4.807,2,1,5]
["S2089","Fenoldopam","e4","L4000-19","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Fenoldopam (SKF 82526) is a selective dopamine-1 (DA1) receptor agonist with natriuretic/diuretic properties with EC50 of 55.5 nM in stimulating cAMP accumulation in LLC-PK1 cells, which is more potent than DA .",305.76,"67227-56-9",{"v":77,"d":"77.00"},251.83,{"v":10,"d":"10.00"},32.71,"http://www.selleckchem.com/products/fenoldopam-corlopam.html","C16H16ClNO3","free base","SKF 82526","OC1=CC=C(C=C1)C2CNCCC3=C(Cl)C(=C(O)C=C23)O",3.053,0,4,1]
["S2174","Hydroxyflutamide (Hydroxyniphtholide)","f4","L4000-19","in 10mM DMSO","Adrenergic Receptor","Endocrinology & Hormones","Hydroxyflutamide (SCH-16423, Hydroxyniphtholide) is an androgen receptor (AR) antagonist and possesses an IC50 of 0.7 μM for the androgen receptor.",292.21,"52806-53-8",{"v":58,"d":"58.00"},198.49,"<1","N/A","http://www.selleckchem.com/products/hydroxyflutamide-sch-16423-hydroxyniphtholide.html","C11H11F3N2O4","free base","Hydroxy-flutamide, SCH-16423","CC(C)(O)C(=O)NC1=CC=C(C(=C1)C(F)(F)F)[N+]([O-])=O",{"v":1.91,"d":"1.910"},1,1,4]
["S2917","Cutamesine Dihydrochloride","g4","L4000-19","in 10mM DMSO","Sigma Receptor","GPCR & G Protein","Cutamesine dihydrochloride (SA4503 dihydrochloride,AGY94806 dihydrochloride) is a potent Sigma-1 receptor agonist with an IC50 of 17.4 nM in guinea pig brain membranes.",441.43,"165377-44-6",{"v":22,"d":"22.00"},49.84,{"v":88,"d":"88.00"},199.35,"http://www.selleckchem.com/products/sa-4503.html","C23H32N2O2.2HCl","Dihydrochloride","SA4503 dihydrochloride, AGY94806 dihydrochloride","Cl.Cl.COC1=C(OC)C=C(CCN2CCN(CCCC3=CC=CC=C3)CC2)C=C1",5.274,2,0,9]
["S2957","Encenicline (EVP-6124) hydrochloride","h4","L4000-19","in 10mM DMSO","AChR","Neuronal Signaling","Encenicline (EVP-6124) hydrochloride is a selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors.",{"v":357.3,"d":"357.30"},"550999-74-1",{"v":71,"d":"71.00"},198.71,"<1","N/A","http://www.selleckchem.com/products/encenicline-hydrochloride.html","C16H17ClN2OS.ClH","hydrochloride","N/A","Cl.ClC1=C2SC(=CC2=CC=C1)C(=O)NC3CN4CCC3CC4",3.773,1,1,2]
["S3405","CRANAD-2","a5","L4000-19","in 10mM DMSO","Beta Amyloid","Neuronal Signaling","CRANAD-2, a near-infrared (NIR) Amyloid-beta (Aβ) plaque-specific fluorescent probe, penetrates the blood brain barrier and has a high affinity for Aβ aggregates with a Kd of 38 nM.",410.26,"1193447-34-5",{"v":20,"d":"20.00"},48.75,"<1","N/A","http://www.selleckchem.com/products/cranad-2.html","C23H25BF2N2O2","free base","N/A","CN(C)C1=CC=C(/C=C/C2=[O;v3][B++;v4]([F;v1])([F-;v1])[O;v3]=C([CH-]2)\\C=C\\C3=CC=C(C=C3)N(C)C)C=C1",5.956,4,0,6]
["S3535","Deudextromethorphan (AVP-786)","b5","L4000-19","in 10mM DMSO","NMDAR","Neuronal Signaling","Deudextromethorphan (AVP-786) is an active N-methyl-D-aspartate (NMDA) receptor antagonist.",277.43,"1079043-55-2",{"v":55,"d":"55.00"},198.25,{"v":14,"d":"14.00"},50.46,"http://www.selleckchem.com/products/deudextromethorphan-avp-786.html","C18H19D6NO","free base","N/A","C(OC1=CC=C2CC3C4CCCCC4(CCN3C([2H])([2H])[2H])C2=C1)([2H])([2H])[2H]",3.674,1,0,3]
["S6087","Indophagolin","c5","L4000-19","in 10mM DMSO","5-HT Receptor,P2 Receptor","Neuronal Signaling","Indophagolin, a potent indoline-containing autophagy inhibitor with IC50 of 140 nM, antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively, also has a strong antagonistic effect on serotonin receptor 5-HT6 with IC50 of 1.0 μM.",523.75,"1207660-00-1",{"v":100,"d":"100.00"},190.93,"<1","N/A","http://www.selleckchem.com/products/indophagolin.html","C19H15BrClF3N2O3S","free base","N/A","FC(F)(F)C1=C(Cl)C=CC(=C1)N[S;v6](=O)(=O)C2=C(Br)C=C3CCN(C(=O)C4CC4)C3=C2",4.831,3,1,5]
["S7478","AF38469","d5","L4000-19","in 10mM DMSO","Others","Neuronal Signaling","AF38469 is a selective, orally bioavailable Sortilin inhibitor with an IC50 value of 330 nM.",324.26,"1531634-31-7",{"v":65,"d":"65.00"},200.46,"<1","N/A","http://www.selleckchem.com/products/af38469.html","C15H11F3N2O3","free base","N/A","CC1=NC(=CC=C1)NC(=O)C2=CC=C(C=C2C(O)=O)C(F)(F)F",2.857,3,1,4]
["S9849","5-(N-Ethyl-N-isopropyl)-Amiloride (EIPA)","e5","L4000-19","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","5-(N-Ethyl-N-isopropyl)-Amiloride (EIPA) acts as an inhibitor of macropinocytosis and sodium-hydrogen exchangers(NHE)  (IC50=0.033μg/mL). EIPA blocks the activity of Na(+)/H(+) exchanger, which are plasma membrane proteins implicated in all forms of macropinocytosis.",299.76,"1154-25-2",{"v":60,"d":"60.00"},200.16,{"v":2,"d":"2.00"},6.67,"http://www.selleckchem.com/products/5-n-ethyl-n-isopropyl-amiloride-eipa.html","C11H18ClN7O","free base","N/A","CCN(C(C)C)C1=C(Cl)N=C(C(=N1)N)C(=O)NC(N)=N",1.236,3,3,5]
["E0070","4F 4PP oxalate","f5","L4000-19","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","4F 4PP oxalate is an antagonist of the serotonin (5-HT) receptor subtype 5-HT2A (Ki = 5.3 nM), which is selective for 5-HT2A receptors over 5-HT1C receptors (Ki = 620 nM).",429.48,"144734-36-1",{"v":11,"d":"11.00"},25.61,"<1","N/A","http://www.selleckchem.com/products/4f-4pp-oxalate.html","C22H26FNO.C2H2O4","oxalate","N/A","OC(=O)C(O)=O.FC1=CC=C(C=C1)C(=O)C2CCN(CCCCC3=CC=CC=C3)CC2",2.489,3,0,8]
["E0079","Compound W","g5","L4000-19","in 10mM DMSO","Secretase","Proteases","Compound W (3,5-Bis(4-nitrophenoxy)benzoic acid) is a 3,3'-diiodothyronine sulfate (3,3'-T2S) cross-reactive material in maternal serum, which can inhibit γ-secretase.",396.31,"173550-33-9",{"v":79,"d":"79.00"},199.34,"<1","N/A","http://www.selleckchem.com/products/compound-w.html","C19H12N2O8","free base","3,5-Bis(4-nitrophenoxy)benzoic acid","OC(=O)C1=CC(=CC(=C1)OC2=CC=C(C=C2)[N+]([O-])=O)OC3=CC=C(C=C3)[N+]([O-])=O",4.369,3,0,7]
["E0083","TSHR antagonist S37","h5","L4000-19","in 10mM DMSO","TSH Receptor","Endocrinology & Hormones","TSHR antagonist S37 is a selective and competitive antagonist of the thyrotropin receptor (TSHR).",460.57,"1217616-61-9",{"v":92,"d":"92.00"},199.75,"<1","N/A","http://www.selleckchem.com/products/tshr-antagonist-s37.html","C25H20N2O3S2","free base","N/A","O=C1NC2=C(S1)C(C3C4CC(C3S2)C5C4C(=O)N(C5=O)C6=CC=CC=C6)C7=CC=CC=C7",3.764,3,1,2]
["E0101","AZD-6280","a6","L4000-19","in 10mM DMSO","GABA Receptor","Transmembrane Transporters","AZD-6280 is a selective GABAA (α2/3) receptor modulator, used for treatment of generalized anxiety disorder.",366.41,"942436-93-3",{"v":73,"d":"73.00"},199.23,"<1","N/A","http://www.selleckchem.com/products/azd-6280.html","C20H22N4O3","free base","N/A","CCCNC(=O)C1=C(N)C2=C(N=N1)C(=CC=C2)C3=C(OC)C=CC(=C3)OC",2.797,5,2,6]
["E0105","ICA-27243","b6","L4000-19","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","ICA-27243, a selective activator of the neuronal M current and KCNQ2/Q3 channels, induces a concentration-dependent increase in a 86Rb+ efflux from CHO cells expressing KCNQ2/Q3 channels with EC50 of 0.2 μM.",268.65,"325457-89-4",{"v":54,"d":"54.00"},201.01,"<1","N/A","http://www.selleckchem.com/products/ica-27243.html","C12H7ClF2N2O","free base","N/A","FC1=C(F)C=C(C=C1)C(=O)NC2=CN=C(Cl)C=C2",2.748,2,1,2]
["E0125","Raclopride","c6","L4000-19","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Raclopride is a selective dopamine D2/D3 receptor antagonist that discriminates between dopamine-mediated motor functions. Raclopride binds to D2 and D3 receptors with dissociation constants of between 1.8 nM and 3.5 nM, but has a very low affinity for D4 receptors.",347.24,"84225-95-6",{"v":69,"d":"69.00"},198.71,{"v":1,"d":"1.00"},2.88,"http://www.selleckchem.com/products/raclopride.html","C15H20Cl2N2O3","free base","N/A","CCN1CCCC1CNC(=O)C2=C(OC)C(=CC(=C2O)Cl)Cl",3.085,2,2,5]
["E0334","BAMB-4","d6","L4000-19","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","BAMB-4 (ITPKA-IN-C14) is a new type of membrane permeable ITPKA inhibitor, and IC50 is 37 μM in the Kinase ADP-Glo assay.",252.27,"891025-25-5",{"v":50,"d":"50.00"},{"v":198.2,"d":"198.20"},"<1","N/A","http://www.selleckchem.com/products/bamb-4.html","C15H12N2O2","free base","N/A","CC1=CC=C(C=C1)C(=O)NC2=NOC3=CC=CC=C23",3.293,3,1,2]
["E0363","Compound 11","e6","L4000-19","in 10mM DMSO","Secretase","Proteases","Compound 11, a non-toxic and selective δ-secretase inhibitor  (IC50=0.7 μM, in fluorescence-based assay) that interacts with both the active site and allosteric site of δ-secretase in Co-crystal structure analysis. The IC50 value of the compound 11 towards δ-secretase in Pala cells is 0.8 μM.",220.23,"842964-18-5",{"v":44,"d":"44.00"},199.79,"<1","N/A","http://www.selleckchem.com/products/compound-11.html","C10H12N4O2","free base","N/A","NC1=CC=C(N2CCOCC2)C3=NON=C13",0.503,4,1,1]
["E0379","SEN12333","f6","L4000-19","in 10mM DMSO","AChR,Calcium Channel","Neuronal Signaling","SEN12333(WAY-317538), a novel selective agonist of alpha7 nicotinic acetylcholine receptor (nAChR), shows high affinity for the rat nAChR expressed in GH4C1 cells with Ki of 260 nM, and acts as full agonist in functional Ca2+ flux studies with EC50 of 1.6 μM.",339.43,"874450-44-9",{"v":68,"d":"68.00"},200.34,"<1","N/A","http://www.selleckchem.com/products/sen12333.html","C20H25N3O2","free base","WAY-317538","O=C(CCCCN1CCOCC1)NC2=CC=C(C=C2)C3=CC=CN=C3",2.037,3,1,7]
["E0388","WQ 1","g6","L4000-19","in 10mM DMSO","Dopamine Receptor,Sigma Receptor","GPCR & G Protein","WQ 1 is a high affinity and selective σ1 receptor antagonist with pKi values of 10.85, 6.53 and 5.80 at σ1, σ2 receptors and dopamine transporter (DAT), displaying σ1/σ2 selectivity ratio of 20893.",337.48,"1204401-49-9",{"v":67,"d":"67.00"},198.53,"<1","N/A","http://www.selleckchem.com/products/wq-1.html","C21H23NOS","free base","N/A","O=C1CC(SC2=CC=CC=C12)C3CCN(CC3)CC4=CC=CC=C4",4.347,1,0,3]
["E0408","JP1302","h6","L4000-19","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","JP-1302(MMV006172), a novel highly selective α2C-adrenoceptor antagonist with Kb of 16 nM at the α2C-adrenoceptor subtype, also produces antidepressant and antipsychotic-like effects.",368.48,"80259-18-3",{"v":74,"d":"74.00"},200.83,"<1","N/A","http://www.selleckchem.com/products/mmv006172.html","C24H24N4","free base","MMV006172","CN1CCN(CC1)C2=CC=C(NC3=C4C=CC=CC4=NC5=CC=CC=C35)C=C2",5.022,1,1,3]
["E0458","RTICBM-189","a7","L4000-19","in 10mM DMSO","Cannabinoid Receptor","GPCR & G Protein","RTICBM-189 is a potent, brain-penetrant allosteric modulator of the cannabinoid type-1 (CB1) receptor with a pIC50 of 7.54 in Ca2+ mobilization assay.",309.19,"551909-15-0",{"v":62,"d":"62.00"},200.52,"<1","N/A","http://www.selleckchem.com/products/rticbm-189.html","C15H14Cl2N2O","free base","N/A","ClC1=CC=C(NC(=O)NCCC2=CC(=CC=C2)Cl)C=C1",4.179,1,2,4]
["E0472","BMS-986122","b7","L4000-19","in 10mM DMSO","Opioid Receptor","GPCR & G Protein","BMS-986122 is a selective, potent positive allosteric modulator of the mu-opioid receptor (µ-OR), shows potentiation of orthosteric agonist-mediated β-arrestin recruitment, adenylyl cyclase inhibition, and G protein activation, and potentiates DAMGO-mediated [35S]GTPγS binding in mouse brain membranes.",448.78,"313669-88-4",{"v":90,"d":"90.00"},200.54,"<1","N/A","http://www.selleckchem.com/products/bms-986122.html","C16H15BrClNO3S2","free base","N/A","COC1=CC=C(C=C1Br)C2SCCN2[S](=O)(=O)C3=CC=C(Cl)C=C3",4.559,3,0,4]
["E0484","CNQX","c7","L4000-19","in 10mM DMSO","GluR","Neuronal Signaling","CNQX (6-cyano-7-nitroquinoxaline-2,3-dione) is an AMPA and kainate receptor antagonist with IC50 values are 0.3 μM and 1.5 μM for AMPA and kainate receptors, respectively. CNQX is also an antagonist at the glycine modulatory site on the NMDA receptor complex (IC50 = 25 μM). CNQX shows neuroprotective effects in models of ischemia and inhibits seizure-like activity in hippocampal neurons.",232.15,"115066-14-3",{"v":46,"d":"46.00"},198.15,"<1","N/A","http://www.selleckchem.com/products/cnqx.html","C9H4N4O4","free base","6-cyano-7-nitroquinoxaline-2,3-dione","[O-][N+](=O)C1=CC2=C(NC(=O)C(=O)N2)C=C1C#N",-0.176,2,2,1]
["E0500","Firocoxib (ML 1785713)","d7","L4000-19","in 10mM DMSO","COX","Immunology & Inflammation","Firocoxib (ML 1785713) is a cyclooxygenase (COX)-2 inhibitor and a nonsteroidal anti-inflammatory drug. In vitro firocoxib inhibits COX-1 and COX-2 with an IC50 of 7.5 mM and 0.13 mM respectively in feline blood.",{"v":336.4,"d":"336.40"},"189954-96-9",{"v":67,"d":"67.00"},199.17,"<1","N/A","http://www.selleckchem.com/products/firocoxib.html","C17H20O5S","free base","ML 1785713","CC1(C)OC(=O)C(=C1C2=CC=C(C=C2)[S](C)(=O)=O)OCC3CC3",2.483,5,0,5]
["E0529","Metipranolol","e7","L4000-19","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Metipranolol (Betamann) is a potent β-adrenergic receptor antagonist, possessing the beta-blocking potencies (pA2) of 8.3, 8.4 at guinea pig atrial β1-adrenoceptor and β2-adrenoceptor of the rat uterus, respectively, also is a potent displacer of 3H-DHA binding, ligand concentration 0.7 nM, possessing a Ki value of 39 ± 24 nM.",{"v":309.4,"d":"309.40"},"22664-55-7",{"v":62,"d":"62.00"},200.39,"<1","N/A","http://www.selleckchem.com/products/metipranolol.html","C17H27NO4","free base","Betamann","CC(C)NCC(O)COC1=CC(=C(OC(C)=O)C(=C1C)C)C",2.858,3,2,8]
["E0535","WAY-303290","f7","L4000-19","in 10mM DMSO","GluR","Neuronal Signaling","WAY-303290 (GluR6 antagonist-1) is a benzothiophene derivative acting as an ionotropic glutamate receptor 6 (GluR6) antagonist, which can be used for researching acute and chronic neurological disorders.",302.78,"323176-64-3",{"v":61,"d":"61.00"},201.47,"<1","N/A","http://www.selleckchem.com/products/way-303290.html","C15H11ClN2OS","free base","GluR6 antagonist-1","ClC1=C(SC2=CC=CC=C12)C(=O)NCC3=CC=CN=C3",3.288,2,1,3]
["E0599","Arecaidine hydrochloride","g7","L4000-19","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Arecaidine hydrochloride, a constituent of the nut of Areca catechu, inhibits the uptake of GABA and beta-alanine, but not that of glycine.",177.63,"6018-28-6",{"v":9,"d":"9.00"},50.67,{"v":36,"d":"36.00"},202.67,"http://www.selleckchem.com/products/arecaidine-hydrochloide.html","C7H11NO2.ClH","hydrochloride","N/A","Cl.CN1CCC=C(C1)C(O)=O",-2.136,1,0,1]
["E0755","Guvacoline hydrochloride","h7","L4000-19","in 10mM DMSO","AChR","Neuronal Signaling","Norarecoline hydrochloride (Guvacoline hydrochloride) is a pyridine alkaloid found in Areca triandra, which can act as a full agonist at both atrial and ileal muscarinic receptors.",177.63,"6197-39-3",{"v":36,"d":"36.00"},202.67,{"v":36,"d":"36.00"},202.67,"http://www.selleckchem.com/products/guvacoline-hydrochloride.html","C7H11NO2.ClH","hydrochloride","Norarecoline hydrochloride","Cl.COC(=O)C1=CCCNC1",0.589,2,1,2]
["E0777","Z944","a8","L4000-19","in 10mM DMSO","Calcium Channel","Neuronal Signaling","Z944 is a highly selective antagonist for T-type calcium channel with IC50s of 50, 160, 110 nM for hCaV3.1, hCaV3.2, and hCaV3.3.",383.89,"1199236-64-0",{"v":19,"d":"19.00"},49.49,"<1","N/A","http://www.selleckchem.com/products/z944.html","C19H27ClFN3O2","free base","N/A","CC(C)(C)NC(=O)CN1CCC(CC1)CNC(=O)C2=CC(=CC(=C2)Cl)F",2.587,2,2,6]
["E0778","o-3M3FBS","b8","L4000-19","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","O-3M3FBS, the negative control of m-3M3FBS, inhibits inward and outward currents via mechanisms independent of PLC acting in an antagonistic manner, reversibly inhibits delayed rectifier K+ channels, increases in [Ca2+](i) in an agonistic manner with m-3M3FBS.",343.36,"313981-55-4",{"v":69,"d":"69.00"},200.96,"<1","N/A","http://www.selleckchem.com/products/o-3m3fbs.html","C16H16F3NO2S","free base","N/A","CC1=CC(=C(C(=C1)C)[S](=O)(=O)NC2=CC=CC=C2C(F)(F)F)C",4.718,2,1,4]
["E0789","SC-58125","c8","L4000-19","in 10mM DMSO","COX","Immunology & Inflammation","SC-58125 is a potent and selective inhibitor of human cyclooxygenase 2 (hCOX-2) and triple mutant of hCOX-2, with an IC50 of 0.04 μM and 1 µM, respectively.",384.35,"162054-19-5",{"v":77,"d":"77.00"},200.34,"<1","N/A","http://www.selleckchem.com/products/sc-58125.html","C17H12F4N2O2S","free base","N/A","C[S](=O)(=O)C1=CC=C(C=C1)[N]2N=C(C=C2C3=CC=C(F)C=C3)C(F)(F)F",4.968,3,0,4]
["E0799","VU 0365114","d8","L4000-19","in 10mM DMSO","AChR","GPCR & G Protein","VU 0365114 is a muscarinic acetylcholine receptor M5-preferring (mAChR M5-preferring) positive allosteric modulator (PAM) with an EC50 of 2.7 μM.",397.35,"1208222-39-2",{"v":79,"d":"79.00"},198.82,"<1","N/A","http://www.selleckchem.com/products/vu-0365114.html","C22H14F3NO3","free base","N/A","FC(F)(F)OC1=CC2=C(C=C1)N(CC3=CC=C(C=C3)C4=CC=CC=C4)C(=O)C2=O",6.098,3,0,5]
["E0809","Timapiprant Sodium","e8","L4000-19","in 10mM DMSO","Prostaglandin Receptor","GPCR & G Protein","Timapiprant sodium (OC000459 sodium), a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known as CRTH2) antagonist, potently displaces [3H]PGD2 from human recombinant DP2, rat recombinant DP2, and human native DP2 with Ki values of 13, 3 and 4 nM, respectively.",371.36,"950688-14-9",{"v":74,"d":"74.00"},199.27,"<1","N/A","http://www.selleckchem.com/products/timapiprant-sodium.html","C21H17FN2O2.Na","Sodium salt","OC000459 sodium","[NaH].CC1=C(CC2=NC3=C(C=CC=C3)C=C2)C4=CC(=CC=C4[N]1CC(O)=O)F",4.329,2,0,4]
["E0814","Masitinib mesylate","f8","L4000-19","in 10mM DMSO","c-Kit,FAK,FGFR,PDGFR,Src","Protein Tyrosine Kinase","Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit with IC50 of 200 nM for human recombinant c-Kit, also inhibits PDGFRα/β with IC50s of 540/800 nM, Lyn with IC50 of 510 nM for LynB, and, to a lesser extent, FGFR3 and FAK.",594.75,"1048007-93-7",{"v":100,"d":"100.00"},168.14,{"v":100,"d":"100.00"},168.14,"https://www.selleckchem.com/products/masitinib-mesylate.html","C28H30N6OS.CH4O3S","Mesylate","AB-1010 mesylate","CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC=C(C)C(=C3)NC4=NC(=CS4)C5=CN=CC=C5.C[S](O)(=O)=O",4.795,3,2,7]
["E0826","Levamlodipine Besylate","g8","L4000-19","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Levamlodipine Besylate is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina.",448.88,"150566-71-5",{"v":100,"d":"100.00"},222.78,{"v":2,"d":"2.00"},4.46,"http://www.selleckchem.com/products/levamlodipine-besylate.html","C20H25ClN2O5.C6H6O3S","Besylate","N/A","CCOC(=O)C1=C(COCCN)NC(=C(C1C2=C(Cl)C=CC=C2)C(=O)OC)C.O[S](=O)(=O)C3=CC=CC=C3",3.473,5,2,11]
["E0829","Nitrocaramiphen hydrochloride","h8","L4000-19","in 10mM DMSO","AChR","Neuronal Signaling","Nitrocaramiphen hydrochloride is an antagonist of muscarinic acetylcholine receptor M1 (mAChR M1), which can completely remove the hyperpolarizing effect of muscarine.",370.87,"98636-73-8",{"v":9,"d":"9.00"},24.27,{"v":3,"d":"3.00"},8.09,"http://www.selleckchem.com/products/nitrocaramiphen-hydrochloride.html","C18H26N2O4.ClH","hydrochloride","N/A","Cl.CCN(CC)CCOC(=O)C1(CCCC1)C2=CC=C(C=C2)[N+]([O-])=O",4.253,2,0,9]
["E0936","IGS-1.76","a9","L4000-19","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","IGS-1.76, a protein-protein interaction (PPI) inhibitor, which exerts drug-like properties showing a significantly affinity for human neuronal calcium sensor 1 (hNCS-1), and efficiently modulates the interaction of hNCS-1 and guanine exchange factor Ric8a.",358.46,"313480-47-6",{"v":72,"d":"72.00"},200.86,"<1","N/A","http://www.selleckchem.com/products/igs-1-76.html","C22H18N2OS","free base","N/A","O=C(CC(C1=CC=CC=C1)C2=CC=CC=C2)NC3=NC4=C(S3)C=CC=C4",5.015,2,1,5]
["E0949","Mebicar","b9","L4000-19","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Mebicar, a derivative of bicyclic bis-ureas, inhibits the orientation reaction in albino mice, potentiates the action of narcotic hypnotics, abolishes the conditioned reflex reaction of avoidance, displays central adrenolytic activity, interferes with the norepinephrine metabolism in the brain stem.",198.22,"10095-06-4",{"v":40,"d":"40.00"},{"v":201.8,"d":"201.80"},{"v":40,"d":"40.00"},{"v":201.8,"d":"201.80"},"http://www.selleckchem.com/products/mebicar.html","C8H14N4O2","free base","N/A","CN1C2C(N(C)C1=O)N(C)C(=O)N2C",-0.582,2,0,0]
["E0960","RO5186582","c9","L4000-19","in 10mM DMSO","GABA Receptor","Transmembrane Transporters","RO5186582 (Basmisanil, RG1662) is a highly selective GABAAα5 negative allosteric modulator.",445.47,"1159600-41-5",{"v":89,"d":"89.00"},199.79,"<1","N/A","http://www.selleckchem.com/products/ro5186582.html","C21H20FN3O5S","free base","Basmisanil, RG1662","CC1=C(COC2=CC=C(C=N2)C(=O)N3CC[S;v6](=O)(=O)CC3)C(=NO1)C4=CC=C(F)C=C4",2.368,7,0,5]
["E1050","PEAQX","d9","L4000-19","in 10mM DMSO","NMDAR","Neuronal Signaling","PEAQX (NVP-AAM077) is an effective and orally available human NMDA antagonist, which shows preference in excess of 100-fold for hNMDA 1A/2A (IC50=of 270 nM) over hNMDA 1A/2B receptors (IC50=29,600 nM).",454.21,"459836-30-7",{"v":91,"d":"91.00"},200.35,"<1","N/A","http://www.selleckchem.com/products/peaqx.html","C17H17BrN3O5P","free base","NVP-AAM077","CC(NC(C1=C2NC(=O)C(=O)NC2=CC=C1)[P;v5](O)(O)=O)C3=CC=C(Br)C=C3",1.733,2,3,5]
["E1093","DNPH1i(N6-benzyladenosine)","e9","L4000-19","in 10mM DMSO","Adenosine Deaminase","Neuronal Signaling","DNPH1i (N6-benzyladenosine,BAPR) is a competitive inhibitor of adenosine deaminase(ADA) from L-1210 cells in axenic culture as well as a potent antiproliferative agent in vitro and in vivo.",357.36,"4294-16-0",{"v":71,"d":"71.00"},198.68,"<1","N/A","http://www.selleckchem.com/products/dnph1i-n6-benzyladenosine.html","C17H19N5O4","free base","N6-benzyladenosine, BAPR","OCC1OC(C(O)C1O)[N]2C=NC3=C(NCC4=CC=CC=C4)N=CN=C23",0.258,4,4,5]
["E1265","Deschloroclozapine","f9","L4000-19","in 10mM DMSO","AChR","Neuronal Signaling","Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs (muscarinic Designer Receptors Exclusively Activated by Designer Drugs) agonist, and binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.",292.38,"1977-07-7",{"v":58,"d":"58.00"},198.37,"<1","N/A","http://www.selleckchem.com/products/deschloroclozapine.html","C18H20N4","free base","N/A","CN1CCN(CC1)C2=NC3=CC=CC=C3NC4=CC=CC=C24",2.758,1,1,1]
["E2356","Tandospirone","g9","L4000-19","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Tandospirone (SM-3997), a potent and selective 5-HT1A receptor partial agonist, with a Ki of 27 nM, has anxiolytic and antidepressant activities.",383.49,"87760-53-0",{"v":26,"d":"26.00"},{"v":67.8,"d":"67.80"},"<1","N/A","http://www.selleckchem.com/products/tandospirone.html","C21H29N5O2","free base","SM-3997","O=C1C2C3CCC(C3)C2C(=O)N1CCCCN4CCN(CC4)C5=NC=CC=N5",1.707,4,0,6]
["E2390","Thalidomide-5-NH2-CH2-COOH","h9","L4000-19","in 10mM DMSO","Trk receptor","Protein Tyrosine Kinase","Thalidomide-5-NH2-CH2-COOH is a potent and selective inhibitor of tropomyosin receptor kinase (Trk).",331.28,"2412056-27-8",{"v":66,"d":"66.00"},199.23,"<1","N/A","http://www.selleckchem.com/products/thalidomide-5-nh2-ch2-cooh.html","C15H13N3O6","free base","N/A","OC(=O)CNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1",-0.613,5,2,4]
["E2517","WAY-388264-A","a10","L4000-19","in 10mM DMSO","Others","Others","WAY-388264-A is a bioactive compound.",296.17,"393129-91-4",{"v":59,"d":"59.00"},199.21,{"v":30,"d":"30.00"},101.29,"http://www.selleckchem.com/products/way-388264-a.html","N/A","free base","N/A","CC1(C)N=C(N)NC(=N1)NC2=CC=C(Br)C=C2",1.707,2,3,2]
["E2521","WAY-327157","b10","L4000-19","in 10mM DMSO","Others","Neuronal Signaling","antidepressant and anxiolytic-like effects;\n5-HT3 receptor antagonist;",279.29,"901599-43-7",{"v":14,"d":"14.00"},50.13,"<1","N/A","http://www.selleckchem.com/products/way-327157.html","C16H13N3O2","free base","N/A","COC1=CC=C(NC(=O)C2=NC3=CC=CC=C3N=C2)C=C1",{"v":2.49,"d":"2.490"},4,1,3]
["E2632","Norharmane","c10","L4000-19","in 10mM DMSO","MAO","Neuronal Signaling","Norharmane (Norharman) is a potent and selective monoamine oxidase A (MAO-A) inhibitor with a Ki of 3.34 μM.",168.19,"244-63-3",{"v":34,"d":"34.00"},202.15,"<1","N/A","http://www.selleckchem.com/products/norharmane.html","C11H8N2","free base","Norharman, β-Carboline","[NH]1C2=C(C=CC=C2)C3=C1C=NC=C3",2.172,1,1,0]
["E2684","Icilin","d10","L4000-19","in 10mM DMSO","TRP Channel","Neuronal Signaling","Icilin is an agonist of the transient receptor potential M8 (TRPM8) ion channel with an EC50 of 1.4 μM.",311.29,"36945-98-9",{"v":62,"d":"62.00"},199.17,"<1","N/A","http://www.selleckchem.com/products/icilin.html","C16H13N3O4","free base","N/A","OC1=C(C=CC=C1)N2CC=C(NC2=O)C3=CC(=CC=C3)[N;v5](=O)=O",2.306,1,2,3]
["P1008","Carbetocin Acetate","e10","L4000-19","in 10mM DMSO","Oxytocin receptor","Endocrinology & Hormones","Carbetocin Acetate is a long-acting oxytocin-analogue and a potent agonist of the oxytocin receptor (OXTR), with improved in vivo stability over oxytocin.",988.16,"37025-55-1",{"v":100,"d":"100.00"},{"v":101.2,"d":"101.20"},{"v":100,"d":"100.00"},{"v":101.2,"d":"101.20"},"http://www.selleckchem.com/peptide/carbetocin-acetate.html","C45H69N11O12S","Acetate","N/A","CCC(C)C1NC(=O)C(CC2=CC=C(OC)C=C2)NC(=O)CCCSCC(NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC1=O)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(N)=O.CC(O)=O",-1.699,13,10,18]
["P1095","BAM (8-22)","f10","L4000-19","in 10mM DMSO","Others","GPCR & G Protein","BAM(8-22), a proteolytically cleaved product of proenkephalin A, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1, and induces scratching in mice in an Mrgpr-dependent manner.",1971.21,"412961-36-5",{"v":100,"d":"100.00"},50.73,{"v":100,"d":"100.00"},50.73,"http://www.selleckchem.com/products/bam--8-22-.html","C91H127N25O23S","Diacetate","N/A","CSCCC(NC(=O)C(CC1=C[NH]C2=CC=CC=C12)NC(=O)C(CC3=C[NH]C4=CC=CC=C34)NC(=O)C(CCC(O)=O)NC(=O)C5CCCN5C(=O)C(CCCNC(N)=N)NC(=O)CNC(=O)C(N)C(C)C)C(=O)NC(CC(O)=O)C(=O)NC(CC6=CC=C(O)C=C6)C(=O)NC(CCC(N)=O)C(=O)NC(CCCCN)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC7=CC=C(O)C=C7)C(=O)NCC(O)=O",-8.438,18,24,62]
["P1108","Bremelanotide Acetate","g10","L4000-19","in 10mM DMSO","Melanocortin Receptor","Endocrinology & Hormones","Bremelanotide Acetate (PT-141 Acetate) is a melanocortin receptor (MCR) agonist recently approved in the USA for the treatment of premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD), as characterized by low sexual desire that causes marked distress or interpersonal difficulty.",1085.22,"1607799-13-2",{"v":100,"d":"100.00"},92.15,{"v":100,"d":"100.00"},92.15,"http://www.selleckchem.com/products/bremelanotide-acetate.html","C50H68N14O10.C2H4O2","Acetate","PT141 Acetate","CCCCC(NC(C)=O)C(=O)NC1CC(=O)NCCCCC(NC(=O)C(CC2=C[NH]C3=CC=CC=C23)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CN=C[NH]5)NC1=O)C(O)=O.CC(O)=O",{"v":0.28,"d":"0.280"},12,12,17]
["P1116","Epitalon","h10","L4000-19","in 10mM DMSO","Telomerase","DNA Damage/DNA Repair","Epitalon is an anti-aging agent and a telomerase activator, with an inhibitory effect of the on the development of spontaneous tumors in mice, as well as geroprotective actions and intranasal administration increases neuronal activity, also can be used for cancer, old age and Retinitis Pigmentosa.",390.35,"307297-39-8",{"v":78,"d":"78.00"},199.82,{"v":78,"d":"78.00"},199.82,"http://www.selleckchem.com/products/epitalon.html","C14H22N4O9","free base","Epithalon","CC(N)C(=O)NC(CCC(O)=O)C(=O)NC(CC(O)=O)C(=O)NCC(O)=O",{"v":-5.93,"d":"-5.930"},6,4,12]
["P1165","Pep2m, myristoylated (TFA)","a11","L4000-19","in 10mM DMSO","GluR","Neuronal Signaling","Pep2m, myristoylated (TFA) is a cell-permeable peptide, which can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions.",1497.83,"N/A",{"v":100,"d":"100.00"},66.76,{"v":25,"d":"25.00"},16.69,"http://www.selleckchem.com/products/pep2m--myristoylated--tfa-.html","C65H119F3N18O16S","free base","N/A","NA","NA","NA","NA","NA"]
["P1220","tat-nr2b9c","b11","L4000-19","in 10mM DMSO","Others","Neuronal Signaling","Tat-NR2B9c (Tat-NR2Bct, NA-1) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively, and disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively, also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy.",2518.88,"500992-11-0",{"v":100,"d":"100.00"},{"v":39.7,"d":"39.70"},{"v":100,"d":"100.00"},{"v":39.7,"d":"39.70"},"http://www.selleckchem.com/products/tat-nr2b9c.html","C105H188N42O30","free base","Nerinetide, NA-1","CCC(C)C(NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCC(N)=O)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CCCNC(N)=N)NC(=O)CNC(=O)C(N)CC1=CC=C(O)C=C1)C(=O)NC(CCC(O)=O)C(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NC(C(C)C)C(O)=O",{"v":-21.34,"d":"-21.340"},23,40,99]
["S8421","Fenebrutinib (GDC-0853)","c11","L4000-19","in 10mM DMSO","BTK","Protein Tyrosine Kinase","Fenebrutinib (GDC-0853) is a potent, selective, and non-covalent bruton's tyrosine kinase (BTK) inhibitor with an Ki value of 0.91 nM for Btk with >100-fold selectivity over 3 off-targets (Bmx :153-fold, Fgr: 168-fold, Src:131-fold).",{"v":664.8,"d":"664.80"},"1434048-34-6",{"v":8,"d":"8.00"},12.03,"<1","N/A","http://www.selleckchem.com/products/fenebrutinib-gdc-0853.html","C37H44N8O4","free base","N/A","CC1CN(CCN1C2=CC=C(NC3=CC(=CN(C)C3=O)C4=CC=NC(=C4CO)N5CC[N]6C7=C(CC(C)(C)C7)C=C6C5=O)N=C2)C8COC8",2.621,5,2,7]
["E2232","Guvacine hydrochloride","d11","L4000-19","in 10mM DMSO","GABA Receptor","Transmembrane Transporters","Guvacine hydrochloride is an alkaloid from the nut of Areca catechu, acts as an inhibitor of GABA transporter, and displays modest selectivity for cloned GABA transporters with IC50s of 14 μM (human GAT-1), 39 μM (rat GAT-1), 58 μM (rat GAT-2), 119 μM (human GAT-3), 378 μM (rat GAT-3), and 1870 μM (human BGT-3).",{"v":163.6,"d":"163.60"},"6027-91-4",{"v":16,"d":"16.00"},{"v":97.8,"d":"97.80"},{"v":33,"d":"33.00"},201.71,"http://www.selleckchem.com/products/guvacine-hydrochloride.html","C6H10ClNO2","hydrochloride","N/A","Cl.OC(=O)C1=CCCNC1",-1.607,1,1,1]
["S0014","HT-2157","e11","L4000-19","in 10mM DMSO","Others","Others","HT-2157 (SNAP37889) is a selective, high-affinity, competitive antagonist of  galanin-3 receptor (Gal3).",366.34,"303149-14-6",{"v":73,"d":"73.00"},199.27,"<1","N/A","http://www.selleckchem.com/products/ht-2157.html","C21H13F3N2O","Free base","SNAP 37889","FC(F)(F)C1=CC=CC(=C1)N=C2C(=O)N(C3=CC=CC=C3)C4=C2C=CC=C4",5.232,2,0,3]
["S0036","PF-06869206","f11","L4000-19","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","PF-06869206 is a selective inhibitor of NPT2a (also referred to as NaPi2a or SLC34A1) with an IC50 of 380 nM.",374.75,"2227425-05-8",{"v":75,"d":"75.00"},200.13,"<1","N/A","http://www.selleckchem.com/products/pf-06869206.html","C15H14ClF3N4O2","Free base","N/A","CC1=C(Cl)C2=NC(=C(C#N)C(=C2[NH]1)N3CCOC(CO)C3)C(F)(F)F",{"v":2.8,"d":"2.800"},2,2,3]
["S0082","PH-002","g11","L4000-19","in 10mM DMSO","Others","Metabolism","PH-002 is an inhibitor of Apolipoprotein E4 (ApoE4) intracellular domain interaction in nerve cells.",491.58,"1311174-68-1",{"v":98,"d":"98.00"},199.36,"<1","N/A","http://www.selleckchem.com/products/ph-002.html","C27H33N5O4","Free base","N/A","CN1N=C(CC(=O)NC2=CC=C(CN3CCN(CC3)C(=O)OC(C)(C)C)C=C2)C4=CC=CC=C4C1=O",{"v":2.87,"d":"2.870"},5,1,7]
["S0113","Eptapirone","h11","L4000-19","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Eptapirone (F11440) is a potent, selective, high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potential.The affinity (pKi) of F11440 for 5-HT1A binding sites is 8.33.",{"v":345.4,"d":"345.40"},"179756-58-2",{"v":69,"d":"69.00"},199.77,"<1","N/A","http://www.selleckchem.com/products/eptapirone.html","C16H23N7O2","Free base","F 11440","CN1C(=O)C=NN(CCCCN2CCN(CC2)C3=NC=CC=N3)C1=O",0.572,5,0,6]
["S0164","AZD-7325","a2","L4000-20","in 10mM DMSO","GABA Receptor","Neuronal Signaling","AZD7325 is a potent and orally active partial selective Positive allosteric modulator (PAM) of GABAAα2 and Aα3 receptor with Ki=0.3 and 1.3 nM, respectively, and has less antagonistic efficacy at the Aα1 and Aα5 receptor subtypes.",354.38,"942437-37-8",{"v":71,"d":"71.00"},200.35,"<1","N/A","http://www.selleckchem.com/products/azd-7325.html","C19H19FN4O2","Free base","N/A","CCCNC(=O)C1=C(N)C2=C(N=N1)C(=CC=C2)C3=C(OC)C=CC=C3F",3.018,4,2,5]
["S0313","Volinanserin","b2","L4000-20","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Volinanserin (Volinanserin Hydrochloride Salt, MDL100907, M 100907, MDL-100,907) is a highly selective and potent 5-HT2 receptor antagonist with Ki of 0.36 nM. Volinanserin shows antipsychotic activity.",373.46,"139290-65-6",{"v":75,"d":"75.00"},200.82,"<1","N/A","http://www.selleckchem.com/products/volinanserin.html","C22H28FNO3","Free base","Volinanserin Hydrochloride Salt, MDL100907, M 100907, MDL-100,907","COC1=C(OC)C(=CC=C1)C(O)C2CCN(CC2)CCC3=CC=C(F)C=C3",{"v":4.02,"d":"4.020"},2,1,7]
["S0447","ASP7663","c2","L4000-20","in 10mM DMSO","Others","Others","ASP7663 is an orally bioavailable selective activator of transient receptor potential ankyrin 1 (TRPA1). ASP7663 activates human, rat and mouse TRPA1 receptors with EC50 of 510 nM, 540 nM and 500 nM, respectively. ASP7663 acts by stimulating 5-HT release from QGP-1 cells and exhibiting an abdominal analgesic effect in vivo.",263.26,"1190217-35-6",{"v":53,"d":"53.00"},201.32,"<1","N/A","http://www.selleckchem.com/products/asp7663.html","C14H14FNO3","Free base","N/A","CC(C)CN1C(=O)C(=C/C(O)=O)/C2=CC=CC(=C12)F",2.445,2,0,3]
["S0476","SCH-23390 hydrochloride","d2","L4000-20","in 10mM DMSO","5-HT Receptor,Dopamine Receptor,Potassium Channel","Neuronal Signaling","SCH-23390 hydrochloride (R-(+)-SCH-23390, SCH-23390) is a highly potent and selective dopamine D1-like receptor antagonist with Ki of 0.2 nM and 0.3 nM for the D1 and D5 dopamine receptor subtypes, respectively. SCH-23390 hydrochloride is a potent and high efficacy agonist at h5-HT2C receptors with Ki of 9.3 nM. SCH-23390 hydrochloride directly inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with IC50 of 268 nM.",324.24,"125941-87-9",{"v":65,"d":"65.00"},200.47,{"v":20,"d":"20.00"},61.68,"http://www.selleckchem.com/products/sch23390.html","C17H19Cl2NO","Hydrochloride","R-(+)-SCH-23390 hydrochloride, SCH-23390 HCl","Cl.CN1CCC2=CC(=C(O)C=C2C(C1)C3=CC=CC=C3)Cl",4.455,0,1,1]
["S0702","α-Conotoxin GI","e2","L4000-20","in 10mM DMSO","AChR","Neuronal Signaling","α-Conotoxin GI, a 13-residue peptide originally isolated from the venom of the fish-hunting cone snail Conus geographus, acts as a competitive antagonist for the muscle-type nicotinic acetylcholine receptor (nAChR) with excellent selectivity for α/δ receptor subunit binding over α/γ.",1437.61,"76862-65-2",{"v":100,"d":"100.00"},69.56,{"v":50,"d":"50.00"},34.78,"http://www.selleckchem.com/products/alpha-conotoxin-gi.html","C55H80N20O18S4","Free base","N/A","CC1NC(=O)C2CCCN2C(=O)C(CC(N)=O)NC(=O)C3CSSCC(NC(=O)C(CO)NC(=O)C(CC4=CC=C(O)C=C4)NC(=O)C(CC5=CN=C[NH]5)NC(=O)C(CCCNC(N)=N)NC(=O)CNC(=O)C(CSSCC(NC(=O)C(N)CCC(O)=O)C(=O)N3)NC1=O)C(N)=O",-11.116,16,19,18]
["S0825","MDR-652","f2","L4000-20","in 10mM DMSO","TRP Channel","Transmembrane Transporters","MDR-652 is a potent and specific agonist of transient receptor potential vanilloid 1 (TRPV1) with Ki of 11.4 nM and 23.8 nM for hTRPV1 and rTRPV1, respectively. MDR-652 has excellent and dose-dependent analgesic activity.",447.95,"1933528-96-1",{"v":90,"d":"90.00"},200.92,"<1","N/A","http://www.selleckchem.com/products/mdr-652.html","C22H23ClFN3O2S","Free base","N/A","CC(C)(C)C1=NC(=C(CNC(=O)NC2=CC(=C(CO)C=C2)F)S1)C3=CC=CC(=C3)Cl",5.082,2,3,6]
["S0862","L-765314","g2","L4000-20","in 10mM DMSO","Adrenergic Receptor","Endocrinology & Hormones","L-765314 is a selective and potent α1b-adrenoceptor (α1b adrenergic receptor) antagonist with an IC50 of 1.90 nM and Kis of 5.4 and 2.0 for rat and human α1b adrenergic receptor, respectively.",{"v":522.6,"d":"522.60"},"189349-50-6",{"v":100,"d":"100.00"},191.35,"<1","N/A","http://www.selleckchem.com/products/l-765314.html","C27H34N6O5","Free base","N/A","COC1=CC2=NC(=NC(=C2C=C1OC)N)N3CCN(C(C3)C(=O)NC(C)(C)C)C(=O)OCC4=CC=CC=C4",3.401,7,2,8]
["S1575","RO4929097","h2","L4000-20","in 10mM DMSO","Beta Amyloid,Notch,Secretase","Proteases","RO4929097 (RG-4733) is a γ secretase inhibitor with IC50 of 4 nM in a cell-free assay, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively. Phase 2.",{"v":469.4,"d":"469.40"},"847925-91-1",{"v":93,"d":"93.00"},198.13,"<1","N/A","http://www.selleckchem.com/products/RO4929097.html","C22H20F5N3O3","Free base","RG-4733","CC(C)(C(=O)NCC(F)(F)C(F)(F)F)C(=O)NC1C(=O)NC2=CC=CC=C2C3=C1C=CC=C3",3.184,3,3,6]
["S1989","GABAA receptor agent 1","a3","L4000-20","in 10mM DMSO","GABA Receptor","Neuronal Signaling","GABAA receptor agent 1 is a high affinity ligand for Gamma-aminobutyric acid A (GABAA) receptor that exerts potent anticonvulsant activity.",273.67,"1571-87-5",{"v":55,"d":"55.00"},200.97,"<1","N/A","http://www.selleckchem.com/products/gabaa-receptor-agent-1.html","C13H8ClN3O2","Free base","N/A","[O-][N+](=O)C1=CC=C2N=C([NH]C2=C1)C3=CC=C(Cl)C=C3",3.829,1,1,2]
["S2975","CarboxyaMidotriazole orotate","b3","L4000-20","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Carboxyamidotriazole Orotate (L-651582 Orotate) is the orotate salt form of Carboxyamidotriazole (CAI), an orally bioavailable signal transduction inhibitor. Carboxyamidotriazole Orotate is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole Orotate inhibits angiogenesis, tumor growth, invasion, and metastasis.",580.76,"187739-60-2",{"v":25,"d":"25.00"},43.05,"<1","N/A","http://www.selleckchem.com/products/carboxyamidotriazole-orotate.html","C22H16Cl3N7O6","Orotate","L-651582 Orotate, CAI Orotate","NC(=O)C1=C(N)[N](CC2=CC(=C(C(=C2)Cl)C(=O)C3=CC=C(Cl)C=C3)Cl)N=N1.OC(=O)C4=CC(=O)NC(=O)N4",{"v":2.65,"d":"2.650"},7,4,6]
["S3191","Azumolene","c3","L4000-20","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Azumolene (EU4093 free base), an equipotent dantrolene analog, is a ryanodine receptor (RyR) modulator that inhibits the calcium-release.",349.14,"64748-79-4",{"v":70,"d":"70.00"},200.49,"<1","N/A","http://www.selleckchem.com/products/azumolene.html","C13H9BrN4O3","Free base","EU4093 free base","BrC1=CC=C(C=C1)C2=CN=C(O2)/C=N/N3CC(=O)NC3=O",1.553,5,1,3]
["S3376","RBPJ Inhibitor-1 (RIN1)","d3","L4000-20","in 10mM DMSO","Notch","Neuronal Signaling","RBPJ Inhibitor-1 (RIN1) is a potent inhibitor of the transcription factor RBPJ that disrupts the interaction between NOTCH and RBPJ.",311.31,"2682114-39-0",{"v":62,"d":"62.00"},199.16,"<1","N/A","http://www.selleckchem.com/products/rin1.html","C17H14FN3O2","Free base","N/A","C[N]1N=CC=C1C2=CC(=C(C=C2)C(N)=O)OC3=CC=CC=C3F",3.057,3,1,4]
["S3510","NLX-101","e3","L4000-20","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","NLX-101 (F-15599) is a highly selective 5-HT1A receptor biased agonist that mediates antidepressant-like activity in rats via prefrontal cortex 5-HT 1A receptors.",394.85,"635323-95-4",{"v":79,"d":"79.00"},200.08,"<1","N/A","http://www.selleckchem.com/products/nlx-101.html","C19H21ClF2N4O","Free base","F-15599","CC1=CN=C(CNCC2(F)CCN(CC2)C(=O)C3=CC(=C(F)C=C3)Cl)N=C1",2.124,3,1,5]
["S3520","AZ10606120 dihydrochloride","f3","L4000-20","in 10mM DMSO","P2 Receptor","Neuronal Signaling","AZ10606120 dihydrochloride (2HCl) is a potent and selective antagonist for P2X7 receptor (P2X7R) with IC50 of ~10 nM. AZ10606120 dihydrochloride exhibits anti-depressant effects and reduces tumour growth.",495.48,"607378-18-7",{"v":99,"d":"99.00"},199.81,{"v":17,"d":"17.00"},34.31,"http://www.selleckchem.com/products/az10606120-dihydrochloride.html","C25H36Cl2N4O2","Dihydrochloride","AZ10606120 2HCl","Cl.Cl.OCCNCCNC1=NC2=C(C=C1)C(=CC=C2)NC(=O)CC34CC5CC(CC(C5)C3)C4",3.902,2,4,9]
["S6639","BAY-545","g3","L4000-20","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","BAY-545 is an A2B adenosine receptor antagonist with ic50 of 59 nM.",433.45,"1699717-32-2",{"v":87,"d":"87.00"},200.72,"<1","N/A","http://www.selleckchem.com/products/bay-545.html","C18H22F3N3O4S","Free base","N/A","CCN1C(=O)N(CCC(F)(F)F)C2=C(C(=C(S2)C(=O)N3CCC(O)CC3)C)C1=O",1.455,3,1,5]
["S6668","NVS-ZP7-4","h3","L4000-20","in 10mM DMSO","Notch,Others","Neuronal Signaling","NVS-ZP7-4,a Zinc transporter SLC39A7 (ZIP7) inhibitor,is the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel druggable node in the Notch pathway.",501.62,"2349367-89-9",{"v":100,"d":"100.00"},199.35,"<1","N/A","http://www.selleckchem.com/products/nvs-zp7-4.html","C28H28FN5OS","Free base","N/A","FC1=CC2=C(C=C1)N=C(NC(CN3CCC4(CC3)NC(=O)NC5=CC=CC=C45)CC6=CC=CC=C6)S2",4.888,2,3,6]
["S6731","Eliprodil (SL-820715)","a4","L4000-20","in 10mM DMSO","NMDAR","Neuronal Signaling","Eliprodil (SL-820715) is a non-competitive NR2B-selective NMDA antagonist with IC50 value of 1 μM and is less potent for NR2A- and NR2C-containing receptors with IC50 > 100 μM.",347.85,"119431-25-3",{"v":15,"d":"15.00"},43.12,"<1","N/A","http://www.selleckchem.com/products/eliprodil.html","C20H23ClFNO","Free base","N/A","OC(CN1CCC(CC1)CC2=CC=C(F)C=C2)C3=CC=C(Cl)C=C3",{"v":4.92,"d":"4.920"},0,1,5]
["S6835","3-deazaadenosine","b4","L4000-20","in 10mM DMSO","Histamine Receptor","Epigenetics","3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 µM, and has anti-inflammatory, anti-proliferative and anti-HIV activity.",266.25,"6736-58-9",{"v":13,"d":"13.00"},48.83,"<1","N/A","http://www.selleckchem.com/products/3-deazaadenosine.html","C11H14N4O4","Free base","N/A","NC1=C2N=C[N](C3OC(CO)C(O)C3O)C2=CC=N1",-1.452,3,4,2]
["S8107","GSK1016790A","c4","L4000-20","in 10mM DMSO","TRP Channel","Transmembrane Transporters","GSK1016790A (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34nM in choroid plexus epithelial cells.",655.61,"942206-85-1",{"v":100,"d":"100.00"},152.53,"<1","N/A","http://www.selleckchem.com/products/gsk1016790a.html","C28H32Cl2N4O6S2","Free base","GSK101","CC(C)CC(NC(=O)C1=CC2=C(S1)C=CC=C2)C(=O)N3CCN(CC3)C(=O)C(CO)N[S](=O)(=O)C4=C(Cl)C=C(Cl)C=C4",3.741,5,3,10]
["S8114","ICI-118551 Hydrochloride","d4","L4000-20","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","ICI-118551 is a highly selective β2-adrenergic receptor antagonist with Ki values of 0.7, 49.5 and 611 nM for β2, β1 and β3 receptors, respectively.",313.86,"72795-01-8",{"v":62,"d":"62.00"},197.54,{"v":21,"d":"21.00"},66.91,"http://www.selleckchem.com/products/ici-118551-ici-118-551.html","C17H27NO2.HCl","Hydrochloride","ICI-118,551","Cl.CC(C)NC(C)C(O)COC1=C2CCCC2=C(C)C=C1",3.934,1,2,6]
["S8524","Edicotinib(JNJ-40346527)","e4","L4000-20","in 10mM DMSO","CSF-1R","Protein Tyrosine Kinase","Edicotinib (JNJ-40346527) is a potent, selective, brain penetrant and orally active colony-stimulating factor-1 receptor (CSF-1R) inhibitor with an IC50 of 3.2 nM.",{"v":461.6,"d":"461.60"},"1142363-52-7",{"v":92,"d":"92.00"},199.31,"<1","N/A","http://www.selleckchem.com/products/edicotinib.html","C27H35N5O2","Free base","N/A","CC1(C)CCC(=CC1)C2=NC(=CC=C2NC(=O)C3=NC=C([NH]3)C#N)C4CC(C)(C)OC(C)(C)C4",{"v":4.56,"d":"4.560"},4,2,4]
["S8600","Elenbecestat","f4","L4000-20","in 10mM DMSO","BACE","Neuronal Signaling","Elenbecestat (E2609) is a novel BACE1 inhibitor, demonstrating prolonged reductions in plasma beta-amyloid levels after single dosing.",437.44,"1388651-30-6",{"v":87,"d":"87.00"},198.88,"<1","N/A","http://www.selleckchem.com/products/elenbecestat.html","C19H18F3N5O2S","Free base","E2609","CC1OCC2(N=C(N)SCC12)C3=C(F)C=CC(=C3)NC(=O)C4=CN=C(C=N4)C(F)F",2.037,5,2,4]
["S8636","Selitrectinib (LOXO-195)","g4","L4000-20","in 10mM DMSO","Trk receptor","Protein Tyrosine Kinase","Selitrectinib (LOXO-195, BAY 2731954) is an orally available, highly potent, and selective TRK kinase inhibitor with low nanomolar inhibitory activity against TRKA G595R, TRKC G623R, and TRKA G667C, IC50s ranging from 2.0 to 9.8 nmol/L. It is more than 1,000-fold selective for 98% of non-TRK kinases tested.",380.42,"2097002-61-2",{"v":38,"d":"38.00"},99.89,"<1","N/A","http://www.selleckchem.com/products/loxo-195.html","C20H21FN6O","Free base","BAY 2731954","CC1CCC2=C(C=C(F)C=N2)C3CCCN3C4=NC5=C(C=N[N]5C=C4)C(=O)N1",2.056,4,1,0]
["S8720","Imaradenant (AZD4635)","h4","L4000-20","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","Imaradenant (AZD4635, HTL1071) is an oral A2AR antagonist that binds to human A2AR with a Ki of 1.7 nM and with > 30-fold selectivity over other adenosine receptors.",315.73,"1321514-06-0",{"v":63,"d":"63.00"},199.54,"<1","N/A","http://www.selleckchem.com/products/adz-4635.html","C15H11ClFN5","Free base","HTL1071","CC1=CC(=CC(=N1)Cl)C2=NN=C(N)N=C2C3=CC=C(F)C=C3",3.463,4,1,2]
["S8890","MK-8719","a5","L4000-20","in 10mM DMSO","OGA","Autophagy","MK-8719 is a selective and potent small molecule inhibitor of the O-GlcNAcase (OGA) enzyme with ki of 7.9nM for hOGA.",268.28,"1382799-40-7",{"v":54,"d":"54.00"},201.28,{"v":54,"d":"54.00"},201.28,"http://www.selleckchem.com/products/mk-8719.html","C9H14F2N2O3S","Free base","N/A","CCNC1=NC2C(O)C(O)C(OC2S1)C(F)F",0.439,2,3,3]
["S9608","Etrumadenant (AB928)","b5","L4000-20","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","Etrumadenant (AB928, A2aR/A2bR antagonist-1) is a novel dual A2aR/A2bR antagonist with Kd of 1.4 nM and 2 nM for A2aR and A2bR, respectively.",426.47,"2239273-34-6",{"v":85,"d":"85.00"},199.31,"<1","N/A","http://www.selleckchem.com/products/ab928.html","C23H22N8O","Free base","A2aR/A2bR antagonist-1","CC1=C(C=CC=C1C#N)C2=CC(=NC(=N2)N)C3=C[N](CC4=CC=CC(=N4)C(C)(C)O)N=N3",{"v":3.75,"d":"3.750"},5,1,5]
["E0041","Tolebrutinib (SAR442168)","c5","L4000-20","in 10mM DMSO","BTK","Angiogenesis","Tolebrutinib (SAR442168, PRN2246, BTKi'168, BTKi('168)) is an oral, CNS-penetrant, irreversible inhibitor of Bruton's tyrosine kinase (BTK) with IC50s of 0.4 nM and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively.",455.51,"1971920-73-6",{"v":91,"d":"91.00"},199.78,"<1","N/A","http://www.selleckchem.com/products/tolebrutinib-sar442168.html","C₂₆H₂₅N₅O₃","Free base","PRN2246","NC1=NC=CC2=C1N(C(=O)N2C3CCCN(C3)C(=O)C=C)C4=CC=C(OC5=CC=CC=C5)C=C4",3.469,4,1,5]
["E0077","Simufilam","d5","L4000-20","in 10mM DMSO","Beta Amyloid","Neuronal Signaling","Simufilam(PTI-125) is a potent, orally active small drug against AD, which interacts to filamin and controls the actin cytoskeleton. Simufilam reduces tau hyperphosphorylation, amyloid and tau formation by preventing and reversing the binding of Aβ42 to α7nAChR.",259.35,"1224591-33-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/simufilam.html","C₁₅H₂₁N₃O","Free base","PTI-125","CN1CCC2(CC1)NCC(=O)N2CC3=CC=CC=C3",1.098,1,1,2]
["E0164","Antazoline Phosphate","e5","L4000-20","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Antazoline Phosphate is the phosphate salt of antazoline. Antazoline is a first-generation antihistaminic agent and acts as a histamine H1 receptor antagonist.",363.35,"154-68-7",{"v":18,"d":"18.00"},49.54,{"v":73,"d":"73.00"},200.91,"http://www.selleckchem.com/products/antazoline-phosphate.html","C17H19N3.H3O4P","Phosphate","N/A","O[P](O)(O)=O.C1CN=C(CN(CC2=CC=CC=C2)C3=CC=CC=C3)N1",2.246,1,1,5]
["E0357","Eliapixant","f5","L4000-20","in 10mM DMSO","P2 Receptor","Neuronal Signaling","Eliapixant (BAY1817080) is a highly potent and selective P2X3 receptor antagonist with a mean IC50 of 8 nM.",478.49,"1948229-21-7",{"v":96,"d":"96.00"},200.63,"<1","N/A","http://www.selleckchem.com/products/eliapixant.html","C22H21F3N4O3S","Free base","BAY 1817080","CC(NC(=O)C1=CC(=CC(=C1)OC2CCOC2)C3=NC=C(C)S3)C4=CN=C(N=C4)C(F)(F)F",2.552,6,1,7]
["E1247","SR95531","g5","L4000-20","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Gabazine(SR95531) is a potent competitive and allosteric antagonist of the GABAA receptor, with an IC50 for the GABA receptor of 9 µM.",368.23,"104104-50-9",{"v":74,"d":"74.00"},200.96,{"v":74,"d":"74.00"},200.96,"https://www.selleckchem.com/products/sr95531.html","C15H18BrN3O3","Free base","Gabazine","Br.COC1=CC=C(C=C1)C2=NN(CCCC(O)=O)C(=N)C=C2",2.233,3,0,6]
["E1257","(R,S)-3,5-DHPG Hydrochloride","h5","L4000-20","in 10mM DMSO","GluR","GPCR & G Protein","(R,S)-3,5-DHPG hydrochloride (DHPG, Dihydroxy phenylglycine) is a salt of free amino acid dihydroxy phenylglycine (DHPG) which acts as a selective and potent agonist of group I metabotropic glutamate receptors (mGluR) (mGluR 1 and mGluR 5).",219.62,"19641-83-9",{"v":44,"d":"44.00"},200.35,{"v":44,"d":"44.00"},200.35,"https://www.selleckchem.com/products/-r-s--3-5-dhpg.html","C8H9NO4","Hydrochloride","DHPG, Dihydroxy phenylglycine","Cl.NC(C(O)=O)C1=CC(=CC(=C1)O)O",-2.029,1,3,2]
["E1258","Pridopidine","a6","L4000-20","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Pridopidine (ACR16, ASP2314, FR310826) , a dopamine (DA) stabilizer, acts as an antagonist against sigma 1 receptor (S1R) and dopamine D2 receptor (D2R).",281.42,"346688-38-8",{"v":57,"d":"57.00"},202.54,"<1","N/A","https://www.selleckchem.com/products/pridopidine.html","C15H23NO2S","Free base","ACR16, ASP2314, FR310826","CCCN1CCC(CC1)C2=CC(=CC=C2)[S;v6](C)(=O)=O",2.919,2,0,4]
["E1259","DNQX","b6","L4000-20","in 10mM DMSO","Calcium Channel,GluR","Neuronal Signaling","DNQX is an AMPA receptor antagonist that prevents excess calcium influx via voltage-gated calcium channels.",252.14,"2379-57-9",{"v":50,"d":"50.00"},{"v":198.3,"d":"198.30"},"<1","N/A","https://www.selleckchem.com/products/dnqx.html","C8H4N4O6","Free base","FG 9041","O=C1NC2=CC(=C(C=C2NC1=O)[N;v5](=O)=O)[N;v5](=O)=O",-0.161,2,2,2]
["E2227","GLN-1062","c6","L4000-20","in 10mM DMSO","Others","Others","GLN-1062 (Memogain) is an inactive pro-drug of galantamine, the latter being a plant alkaloid approved for the treatment of mild to moderate Alzheimer's disease.",391.46,"224169-27-1",{"v":78,"d":"78.00"},199.25,"<1","N/A","http://www.selleckchem.com/products/gln-1062.html","C24H25NO4","Free base","Memogain","COC1=C2OC3CC(OC(=O)C4=CC=CC=C4)C=CC35CCN(C)CC(=C25)C=C1",3.485,4,0,4]
["E2515","JT010","d6","L4000-20","in 10mM DMSO","TRP Channel","Neuronal Signaling","JT010 is a potent agonist of transient receptor potential cation channel subfamily A member 1 (TRPA1) with an EC50 of 0.65 nM.",354.85,"917562-33-5",{"v":71,"d":"71.00"},200.08,"<1","N/A","http://www.selleckchem.com/products/jt010.html","C16H19ClN2O3S","Free base","N/A","COCCCN(C(=O)CCl)C1=NC(=CS1)C2=CC=C(OC)C=C2",2.548,4,0,8]
["E2809","WAY-328168","e6","L4000-20","in 10mM DMSO","Others","Others","WAY-328168 is a bioactive compound.",397.86,"909856-46-8",{"v":10,"d":"10.00"},25.13,"<1","N/A","https://www.selleckchem.com/products/way-328168.html","C21H20ClN3O3","Free base","N/A","COC1=C(C=CC=C1)N2CCN(CC2)C(=O)C3=NOC(=C3)C4=CC=C(Cl)C=C4",4.213,4,0,4]
["E2848","Afoxolaner","f6","L4000-20","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Afoxolaner (NexGard) is a new insecticide/acaricide molecule from the isoxazoline family that acts on the insect gamma-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod.",625.87,"1093861-60-9",{"v":100,"d":"100.00"},159.78,"<1","N/A","https://www.selleckchem.com/products/afoxolaner.html","C26H17ClF9N3O3","Free base","NexGard","FC(F)(F)CNC(=O)CNC(=O)C1=CC=C(C2=NOC(C2)(C3=CC(=CC(=C3)Cl)C(F)(F)F)C(F)(F)F)C4=C1C=CC=C4",5.876,4,2,9]
["P1106","D-JNKI-1","g6","L4000-20","in 10mM DMSO","JAK","MAPK","D-JNKI-1 (AM-111, XG-102, Brimapitide) is a highly and cell-permeable peptide inhibitor of JNK.",{"v":3822.5,"d":"3822.50"},"1445179-97-4",{"v":100,"d":"100.00"},26.16,{"v":50,"d":"50.00"},13.08,"http://www.selleckchem.com/products/d-jnki-1.html","C₁₆₄H₂₈₆N₆₆O₄₀","Free base","AM-111, XG-102, Brimapitide","CC(C)CC(NC(=O)C(CC1=CC=CC=C1)NC(=O)C2CCCN2C(=O)C(CCC(N)=O)NC(=O)C(NC(=O)C3CCCN3C(=O)C(CCCNC(N)=N)NC(=O)C(CO)NC(=O)C(CCC(N)=O)NC(=O)C(N)CC(O)=O)C(C)C)C(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)N4CCCC4C(=O)NC(CCCNC(N)=N)C(=O)NC(CCCCN)C(=O)N5CCCC5C(=O)NC(CCCNC(N)=N)C(=O)N6CCCC6C(=O)N7CCCC7C(=O)NC(CCCNC(N)=N)C(=O)NC(CCCNC(N)=N)C(=O)NC(CCCNC(N)=N)C(=O)NC(CCC(N)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(CCCNC(N)=N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCNC(N)=N)C(=O)NCC(N)=O",-23.996,36,54,135]
["P1208","PMX 205","h6","L4000-20","in 10mM DMSO","CD markers","Transmembrane Transporters","PMX 205 is a cyclic hexapeptide that acts as a potent C5a receptor (C5aR, CD88) antagonist with an IC50 of 31 nM.",839.04,"514814-49-4",{"v":100,"d":"100.00"},119.18,{"v":50,"d":"50.00"},59.59,"http://www.selleckchem.com/products/pmx-205.html","C45H62N10O6","Free base","N/A","NC(N)=NCCCC1NC(=O)C(CC2=C[NH]C3=CC=CC=C23)NC(=O)C(CC4CCCCC4)NC(=O)C5CCCN5C(=O)C(CCCNC1=O)NC(=O)CCC6=CC=CC=C6",3.088,7,8,12]
["E4112","Menthol","a7","L4000-20","in 10mM DMSO","Others","Others","Menthyl alcohol is an organic compound made synthetically or obtained from peppermint or mint oils with flavoring and local anesthetic properties.",156.26,"1490-04-6","N/A",">10","N/A","N/A","https://www.selleckchem.com/products/menthol.html","C10H20O","free base","Menthyl alcohol","CC(C)C1CCC(C)CC1O",2.779,0,1,1]
["E4298","(-)-Carvone","b7","L4000-20","in 10mM DMSO","Others","Others","(-)-Carvone is a natural product which probably has antioxidant and anti-inflammatory capabilities.",150.22,"6485-40-1","N/A",">10","N/A","N/A","https://www.selleckchem.com/products/carvone.html","C10H14O","free base","(-)-Carvone","CC(=C)C1CC=C(C)C(=O)C1",2.501,1,0,1]
["E1119","EG00229","c7","L4000-20","in 10mM DMSO","Others","Others","EG00229 is a neuropilin 1 (NRP1) receptor antagonist with an IC50 of 3 μM against VEGF-A binding to NRP1 b1 domain.",{"v":611.6,"d":"611.60"},"1210945-69-9",{"v":100,"d":"100.00"},163.51,"<1","N/A","https://www.selleckchem.com/products/eg00229.html","C17H19N7O5S3.C2HF3O2","trifluoroacetate","N/A","NC(=N)NCCCC(NC(=O)C1=C(N[S](=O)(=O)C2=CC=CC3=NSN=C23)C=CS1)C(O)=O.OC(=O)C(F)(F)F",1.787,7,4,12]
["E1218","K6PC-5","d7","L4000-20","in 10mM DMSO","SPHK","Immunology & Inflammation","K6PC-5, a ceramide derivative, is a sphingosine kinase 1 (SPHK1) activator and elicits a rapid transient increase in intracellular calcium levels.",{"v":343.5,"d":"343.50"},"756875-51-1",{"v":69,"d":"69.00"},200.87,{"v":69,"d":"69.00"},200.87,"https://www.selleckchem.com/products/k6pc-5.html","C19H37NO4","free base","N/A","CCCCCCCC(=O)C(CCCCCC)C(=O)NC(CO)CO",3.926,2,3,16]
["E1220","CBR-470-1","e7","L4000-20","in 10mM DMSO","phosphoglycerate kinase","Metabolism","CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1 is also a non-covalent Nrf2 activator. CBR-470-1 protects SH-SY5Y neuronal cells against MPP+-induced cytotoxicity through activation of the Keap1-Nrf2 cascade.",{"v":365.9,"d":"365.90"},"2416095-06-0",{"v":73,"d":"73.00"},199.51,"<1","N/A","https://www.selleckchem.com/products/cbr-470-1.html","C14H20ClNO4S2","chlorosulfate","N/A","CC(C)CNC1C[S](=O)(=O)CC1[S](=O)(=O)C2=CC=C(Cl)C=C2",2.289,4,1,5]
["E1256","Ibotenic acid","f7","L4000-20","in 10mM DMSO","Others","Others","Ibotenic acid((RS)-Ibotenic acid; DL-Ibotenic acid) is a neuroexcitatory amino acid originally isolated from Amanita species. It exhibits agonist activity at both N-methyl-D-aspartate (NMDA) and trans-ACPD) or metabolotropic quisqualate (Qm) receptor sites.",158.11,"2552-55-8",{"v":32,"d":"32.00"},202.39,{"v":4,"d":"4.00"},{"v":25.3,"d":"25.30"},"https://www.selleckchem.com/products/ibotenicacid.html","C5H6N2O4","free base","(RS)-Ibotenic acid; DL-Ibotenic acid","NC(C(O)=O)C1=CC(=O)NO1",-4.472,3,2,2]
["E1310","DPCPX","g7","L4000-20","in 10mM DMSO","Others","Others","DPCPX (PD 116948), a xanthine derivative, is a highly potent and selective adenosine A1 receptor (ADORA1) antagonist, with a Ki of 0.46 nM.",304.39,"102146-07-6",{"v":61,"d":"61.00"},{"v":200.4,"d":"200.40"},"<1","N/A","https://www.selleckchem.com/products/dpcpx.html","C16H24N4O2","free base","PD 116948","CCCN1C(=O)N(CCC)C2=C([NH]C(=N2)C3CCCC3)C1=O",{"v":3.37,"d":"3.370"},3,1,5]
["E1333","wiskostatin","h7","L4000-20","in 10mM DMSO","Others","Cytoskeleton","Wiskostatin is a potent and selective inhibitor of neuronal Wiskott-Aldrich syndrome protein (N-WASP)-mediated actin polymerization. Wiskostatin causes a rapid, profound, and irreversible decrease in cellular ATP levels.",426.15,"253449-04-6",{"v":85,"d":"85.00"},199.46,"<1","N/A","https://www.selleckchem.com/products/wiskostatin.html","C17H18Br2N2O","free base","N/A","CN(C)CC(O)C[N]1C2=CC=C(Br)C=C2C3=CC(=CC=C13)Br",4.654,0,1,4]
["E1368","PD173212","a8","L4000-20","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","PD173212(Compound 11) is a selective N-type voltage sensitive calcium channel (VSCC) blocker, with an IC50 of 36 nM in IMR-32 assays.",599.85,"217171-01-2",{"v":100,"d":"100.00"},166.71,"<1","N/A","https://www.selleckchem.com/products/pd173212.html","C38H53N3O3","free base","Compound 11","CC(C)CC(N(C)CC1=CC=C(C=C1)C(C)(C)C)C(=O)NC(CC2=CC=C(OCC3=CC=CC=C3)C=C2)C(=O)NC(C)(C)C",7.678,3,2,15]
["E1410","Fluspirilene","b8","L4000-20","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Fluspirilene(R 6218; Redeptin) is a non-competitive antagonist of L-type calcium channels with an IC50 of 0.03 μM in cell-free assays. Fluspirileneis a long-acting injectable depot antipsychotic agent used for schizophrenia.",475.57,"1841-19-6",{"v":95,"d":"95.00"},199.76,"<1","N/A","https://www.selleckchem.com/products/fluspirilene.html","C29H31F2N3O","free base","R 6218, Redeptin","FC1=CC=C(C=C1)C(CCCN2CCC3(CC2)N(CNC3=O)C4=CC=CC=C4)C5=CC=C(F)C=C5",5.545,1,1,7]
["E2153","TRYPTAMINE HYDROCHLORIDE","c8","L4000-20","in 10mM DMSO","Others","Others","Tryptamine hydrochloride is a derivative of the amino acid tryptophan. Tryptamine hydrochloride is psychoactive and acts as a neurotransmitter in the body, affecting mood, perception and cognition. Tryptamine is synthesized by decarboxylation of L-tryptophan and occurs endogenously at low concentrations in the mammalian brain. In its hydrochloride form, Tryptamine hydrochloride hydrochloride, it is commonly used as a research chemical and as a starting material for the synthesis of other organic compounds.",196.68,"343-94-2",{"v":39,"d":"39.00"},198.29,{"v":39,"d":"39.00"},198.29,"https://www.selleckchem.com/products/triptamine-hydrochloride.html","C10H12N2.ClH","HYDROCHLORIDE","N/A","Cl.NCCC1=C[NH]C2=CC=CC=C12",1.932,0,2,2]
["E2868","Naloxegol Oxalate","d8","L4000-20","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","Naloxegol oxalate (NKTR-118 oxalate) is a μ-opioid-receptor antagonist with a Ki of 33.8 nM. Naloxegol oxalate inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation.",741.82,"1354744-91-4",{"v":100,"d":"100.00"},{"v":134.8,"d":"134.80"},{"v":100,"d":"100.00"},{"v":134.8,"d":"134.80"},"https://www.selleckchem.com/products/naloxegol-oxalate.html","C34H53NO11.C2H2O4","oxalate","N/A","COCCOCCOCCOCCOCCOCCOCCOC1CCC2(O)C3CC4=C5C(=C(O)C=C4)OC1C25CCN3CC=C.OC(=O)C(O)=O",-2.512,11,1,25]
["E2871","Trovafloxacin Mesylate","e8","L4000-20","in 10mM DMSO","TRP Channel","Transmembrane Transporters, Microbiology  & Antibiotic","Trovafloxacin mesylate, a broad-spectrum quinolone antibiotic, is a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current.",512.46,"147059-75-4",{"v":100,"d":"100.00"},195.14,"<1","N/A","https://www.selleckchem.com/products/trovafloxacin-mesylate.html","C20H15F3N4O3.CH4O3S","methanesulfonic","N/A","C[S](O)(=O)=O.NC1C2CN(CC12)C3=C(F)C=C4C(=O)C(=CN(C5=C(F)C=C(F)C=C5)C4=N3)C(O)=O",{"v":-0.68,"d":"-0.680"},3,1,3]
["E2874","Sofpironium bromide","f8","L4000-20","in 10mM DMSO","AChR","Neuronal Signaling","Sofpironium bromide (BBI 4000) is an anticholinergic agent that reduces sweat by inhibiting  M3 muscarinic receptors  in eccrine glands.",{"v":470.4,"d":"470.40"},"1628106-94-4",{"v":94,"d":"94.00"},199.83,{"v":94,"d":"94.00"},199.83,"https://www.selleckchem.com/products/sofpironium-bromide.html","C22H32NO5.Br","bromide","BBI 4000","[Br-].CCOC(=O)C[N+]1(C)CCC(C1)OC(=O)C(O)(C2CCCC2)C3=CC=CC=C3",-0.905,4,0,9]
["E2875","Levobunolol(l-Bunolol) hydrochloride","g8","L4000-20","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Levobunolol (l-Bunolol) hydrochloride is a potent and nonselective β-adrenergic receptor antagonist with an IC50 of 48 μM.",327.85,"27912-14-7 ",{"v":66,"d":"66.00"},201.31,{"v":66,"d":"66.00"},201.31,"https://www.selleckchem.com/products/levobunolol-l-bunolol-hydrochloride.html","C17H25NO3.ClH","hydrochloride","N/A","Cl.CC(C)(C)NCC(O)COC1=C2CCCC(=O)C2=CC=C1",{"v":2.74,"d":"2.740"},2,2,6]
["E2880","methylnaltrexone bromide","h8","L4000-20","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","Methylnaltrexone bromide is an antagonist of µ-opioid receptor that reduces the viability of lung cancer cells by inhibiting Src activation.",436.34,"73232-52-7",{"v":100,"d":"100.00"},229.18,{"v":100,"d":"100.00"},229.18,"https://www.selleckchem.com/products/methylnaltrexone-bromide.html","C21H26NO4.Br","bromide","N/A","[Br-].C[N+]1(CCC23C4OC5=C(O)C=CC(=C25)CC1C3(O)CCC4=O)CC6CC6",-2.116,2,1,2]
["E2901","(-)-Isoproterenol hydrochloride","a9","L4000-20","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","(-)-Isoproterenol hydrochloride is an agonist of  beta-adrenergic receptor. (-)-Isoproterenol hydrochloride is also used in the treatment of bradycardia; bronchodilator.",247.72,"5984-95-2",{"v":50,"d":"50.00"},201.84,{"v":50,"d":"50.00"},201.84,"https://www.selleckchem.com/products/---isoproterenol-hydrochloride.html","C11H17NO3.CIH","hydrochloride","N/A","Cl.CC(C)NCC(O)C1=CC(=C(O)C=C1)O",1.481,0,4,4]
["E2943","Pifithrin-β","b9","L4000-20","in 10mM DMSO","p53","Apoptosis","Pifithrin-β (PFT β hydrobromide; Cyclic Pifithrin-α hydrobromide) is a potent inhibitor of p53 with an IC50 of 23 μM and is regarded as a lead compound for cancer and neurodegenerative disease therapy.",268.38,"60477-34-1",{"v":27,"d":"27.00"},{"v":100.6,"d":"100.60"},"<1","N/A","https://www.selleckchem.com/products/pifithrin-beta.html","C16H16N2S","free base","PFT β hydrobromide; Cyclic Pifithrin-α hydrobromide","CC1=CC=C(C=C1)C2=C[N]3C4=C(CCCC4)SC3=N2",4.125,1,0,1]
["E2944","Norepinephrine hydrochloride","c9","L4000-20","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent agonist of adrenergic receptor (AR). Norepinephrine activates α1, α2, β1 receptors.",205.64,"329-56-6",{"v":41,"d":"41.00"},199.38,{"v":41,"d":"41.00"},199.38,"https://www.selleckchem.com/products/norepinephrine-hydrochloride.html","C8H11NO3.ClH","hydrochloride","Levarterenol; L-Noradrenaline","Cl.NCC(O)C1=CC(=C(O)C=C1)O",0.323,0,4,2]
["E2948","β-Amyloid (25-35)","d9","L4000-20","in 10mM DMSO","Beta Amyloid","Neuronal Signaling","β-Amyloid (25-35) (Amyloid beta-peptide (25-35), Aβ25-35, β-Amyloid peptide (25-35)) , a sequence GSNKGAIIGLM, is a highly toxic synthetic derivative of Amyloid beta-peptide (Aβ-peptides) which forms fibrillary aggregates. β-Amyloid (25-35) is involved in the pathogenesis of Alzheimer's disease.",1060.27,"131602-53-4",{"v":100,"d":"100.00"},94.32,"<1","N/A","https://www.selleckchem.com/products/beta-amyloid-25-35.html","C45H81N13O14S","sulfate","Amyloid beta-peptide (25-35); Aβ25-35; β-Amyloid peptide (25-35), β-淀粉样蛋白 (25-35)","CCC(C)C(NC(=O)C(NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(N)=O)NC(=O)C(CO)NC(=O)CN)C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(O)=O",{"v":-7.23,"d":"-7.230"},12,14,37]
["E2964","Norepinephrine tartrate","e9","L4000-20","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Norepinephrine tartrate is a potent agonist of adrenergic receptor (AR). Norepinephrine activates α1, α2, β1 receptors.",319.27,"3414-63-9",{"v":64,"d":"64.00"},200.46,{"v":64,"d":"64.00"},200.46,"https://www.selleckchem.com/products/norepinephrine-tartrate.html","C8H11NO3.C4H6O6","bitartrate","N/A","NCC(O)C1=CC(=C(O)C=C1)O.OC(C(O)C(O)=O)C(O)=O",-4.202,2,6,5]
["E2984","GSK-7975A","f9","L4000-20","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","GSK-7975A is a potent and orally available inhibitor of CRAC channel. It reduces FcεRI-dependent Ca2+ influx and reduces the release of histamine, leukotriene C4, and cytokines (IL-5/-8/-13 and TNFα).",{"v":397.3,"d":"397.30"},"1253186-56-9",{"v":79,"d":"79.00"},198.84,"<1","N/A","https://www.selleckchem.com/products/gsk-7975a.html","C18H12F5N3O2","free base","N/A","OC1=CC(=C(C[N]2C=CC(=N2)NC(=O)C3=C(F)C=CC=C3F)C=C1)C(F)(F)F",4.498,2,2,5]
["E2993","Ruthenium Red","g9","L4000-20","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye, which is a L-type calcium current  (ICa) blocker. It is  widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red strongly reacts with phospholipids and fatty acids and binds to acidic mucopolysaccharides.",786.35,"11103-72-3",{"v":100,"d":"100.00"},127.17,{"v":100,"d":"100.00"},127.17,"https://www.selleckchem.com/products/ruthenium-red.html","N/A","oxychloride","Ammoniated ruthenium oxychloride","N/A","N/A","N/A","N/A","N/A"]
["E2998","Acetylthiocholine iodide","h9","L4000-20","in 10mM DMSO","Others","Others","Acetylthiocholine iodide(S-Acetylthiocholine iodide; ATCh iodide) is used as a substrate in the preparation of acetylcholine esterase (AChE) assay working solution for AChE activity assay. In addition, the compound is used in some medical research, for example in the fields of neuroscience and organ physiology.",289.18,"1866-15-5",{"v":58,"d":"58.00"},200.57,{"v":58,"d":"58.00"},200.57,"https://www.selleckchem.com/products/acetylthiocholine-iodide.html","C7H16NOS.I","iodide","S-Acetylthiocholine iodide; ATCh iodide","[I-].CC(=O)SCC[N+](C)(C)C",-3.749,1,0,4]
["E4032","5'-Deoxy-5'-(methylthio)adenosine","a10","L4000-20","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","5'-Deoxy-5'-(methylthio)adenosine (Methylthioadenosine, MTA) is a naturally occurring sulfur-containing nucleoside produced by the decarboxylation of S-adenosylmethionine. This nucleoside is a potent agonist of adenosine receptors with Ki of  0.15, 1.13, 13.9, and 0.68 μM for A1, A2A, A2B, and A3, respectively.",297.34,"2457-80-9",{"v":59,"d":"59.00"},198.43,{"v":6,"d":"6.00"},20.18,"https://www.selleckchem.com/products/5-deoxy-5-methylthio-adenosine.html","C11H15N5O3S","free base","Methylthioadenosine, MTA","CSCC1OC(C(O)C1O)[N]2C=NC3=C(N)N=CN=C23",-0.728,4,3,3]
["S1423","Dobutamine HCl","b10","L4000-20","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Dobutamine(Dobutrex) hydrochloride is a selective potent agonist of β1-AR (β-1 adrenergic receptor) and exhibits weak activity at α1-AR and β2-AR. Dobutamine is a sympathomimetic compound that effectively restores blood pressure in hypotensive dogs and human patients by improving myocardial contractility and increasing cardiac output (CO).",337.84,"49745-95-1",{"v":68,"d":"68.00"},201.28,"<1","N/A","https://www.selleckchem.com/products/Dobutamine-hydrochloride.html","C18H23NO3&middot;HCl","hydrochloride","Dobutrex","Cl.CC(CCC1=CC=C(O)C=C1)NCCC2=CC(=C(O)C=C2)O",4.083,0,4,7]
["S8212","Olcegepant","c10","L4000-20","in 10mM DMSO","CGRP Receptor","GPCR & G Protein","Olcegepant (BIBN4096; BIBN4096BS) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with an IC50 of 0.03 nM.",869.65,"204697-65-4",{"v":100,"d":"100.00"},114.99,"<1","N/A","https://www.selleckchem.com/products/olcegepant.html","C38H47Br2N9O5","free base","BIBN4096; BIBN4096BS","NCCCCC(NC(=O)C(CC1=CC(=C(O)C(=C1)Br)Br)NC(=O)N2CCC(CC2)N3CC4=CC=CC=C4NC3=O)C(=O)N5CCN(CC5)C6=CC=NC=C6",2.776,5,5,12]
["E0109","Fezolinetant","d10","L4000-20","in 10mM DMSO","Neurokinin Receptor","GPCR & G Protein","Fezolinetant (ESN-364) is a potential antagonist of the neurokinin 3 receptor (NK3R). It interrupts pulsatile lh secretion and moderates levels of ovarian hormones throughout the menstrual cycle.",358.39,"1629229-37-3",{"v":72,"d":"72.00"},{"v":200.9,"d":"200.90"},"<1","N/A","https://www.selleckchem.com/products/fezolinetant.html","C₁₆H₁₅FN₆OS","free base","ESN-364","CC1N(CC[N]2C1=NN=C2C3=NC(=NS3)C)C(=O)C4=CC=C(F)C=C4",1.714,5,0,2]
["E1579","UCL-TRO-1938","e10","L4000-20","in 10mM DMSO","PI3K","PI3K/Akt/mTOR","UCL-TRO-1938 is a potent allosteric activator of PI3Kα with an EC50 value of approximately 60 μM. UCL-TRO-1938 can induce cell proliferation and has cardioprotective and neural regeneration effects.",456.58,"2919575-27-0",{"v":30,"d":"30.00"},65.71,"<1","N/A","https://www.selleckchem.com/products/ucl-tro-1938.html","C27H32N6O","free base","N/A","CCN1CCN(CC1)C2=CC=C(NC3=CC(=CC=N3)NC4=C5N(CCC5=CC=C4)C(C)=O)C=C2",4.188,2,2,6]
["E1603","ACT001(DMAMCL)","f10","L4000-20","in 10mM DMSO","PAI-1","Metabolism","ACT001(DMAMCL, dimethylaminomicheliolide) is a PAI-1 inhibitor and exerts antitumor effects on neuroblastoma (NB) both in vitro and in vivo. It also exerts synergistic effects in combination with cisplatin through the inhibition of the PAI-1/PI3K/AKT pathway.",{"v":293.4,"d":"293.40"},"1403357-81-2",{"v":59,"d":"59.00"},201.09,{"v":59,"d":"59.00"},201.09,"https://www.selleckchem.com/products/act001-dmamcl.html","C17H27NO3","free base","DMAMCL, dimethylaminomicheliolide","CN(C)CC1C2CCC(=C3CCC(C)(O)C3C2OC1=O)C",1.913,2,0,2]
["E1742","Reversan","g10","L4000-20","in 10mM DMSO","P-gp","Transmembrane Transporters","Reversan (CBLC4H10) is a selective and nontoxic inhibitor of multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (P-gp), with the potential to treat neuroblastoma and other MRP1-overexpressing drug-refractory tumors.",441.53,"313397-13-6",{"v":18,"d":"18.00"},40.77,"<1","N/A","https://www.selleckchem.com/products/reversan.html","C26H27N5O2","free base","CBLC4H10","O=C(NCCCN1CCOCC1)C2=C3N=C(C=C([N]3N=C2)C4=CC=CC=C4)C5=CC=CC=C5",3.093,4,1,7]
["E1773","Fasoracetam (NS 105)","h10","L4000-20","in 10mM DMSO","GluR","Neuronal Signaling","Fasoracetam (NS 105) is a metabotropic glutamate receptor activator with a potential to treat vascular dementia.",196.25,"110958-19-5",{"v":39,"d":"39.00"},198.73,{"v":39,"d":"39.00"},198.73,"https://www.selleckchem.com/products/fasoracetam-ns-105.html","C10H16N2O2","free base","NS 105","O=C1CCC(N1)C(=O)N2CCCCC2",-0.053,2,1,1]
["E2985","Capadenoson","a11","L4000-20","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","Capadenoson (BAY 68-4986) is an orally bioavailable, non-nucleoside partial adenosine A1 receptor agonist that exhibits an anti-ischemic effect.",520.03,"544417-40-5",{"v":50,"d":"50.00"},96.15,"<1","N/A","https://www.selleckchem.com/products/capadenoson.html","C25H18ClN5O2S2","free base","BAY 68-4986","NC1=NC(=C(C#N)C(=C1C#N)C2=CC=C(OCCO)C=C2)SCC3=CSC(=N3)C4=CC=C(Cl)C=C4",5.116,3,2,8]
["E4024","Poly-D-lysine hydrobromide","b11","L4000-20","in 10mM DMSO","Others","Others","Poly-D-lysine hydrobromide is a synthetic polymeric substrate most widely used in neural cell culture. It removes proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells without affecting PrPC.",{"v":227.1,"d":"227.10"},"27964-99-4",{"v":45,"d":"45.00"},198.15,{"v":45,"d":"45.00"},198.15,"https://www.selleckchem.com/products/poly-d-lysine-hydrobromide.html","(C6H14N2O2)x.xBrH","hydrobromide","N/A","Br.NCCCCC(N)C(O)=O",-2.749,1,2,5]
["E4031","8-Cyclopentyl-1,3-dimethylxanthine","c11","L4000-20","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","8-Cyclopentyl-1,3-dimethylxanthine is a selective adenosine A1 receptor antagonist with Ki's of 10.9 nM and 1440 nM for A1 receptor and A2 receptor, respectively.",248.28,"35873-49-5",{"v":25,"d":"25.00"},100.69,"<1","N/A","https://www.selleckchem.com/products/8-cyclopentyl-1-3-dimethylxanthine.html","C12H16N4O2","free base","N/A","CN1C(=O)N(C)C2=C([NH]C(=N2)C3CCCC3)C1=O",1.625,3,1,1]
["E4042","5,5-Dimethyl-1-pyrroline N-oxide","d11","L4000-20","in 10mM DMSO","Others","Others","5,5-Dimethyl-1-pyrroline N-oxide (DMPO) is a cell-permeable hydrophilic spin trap agent for superoxide detection. It acts as a neuroprotective agent and incubating lymphocytes with DMPO decreases DNA damage by NiCl2.",113.16,"3317-61-1",{"v":23,"d":"23.00"},203.25,{"v":23,"d":"23.00"},203.25,"https://www.selleckchem.com/products/5,5-dimethyl-1-pyrroline-n-oxide.html","C6H11NO","free base","DMPO","CC1(C)CCC=[N]1=O",0.757,0,0,0]
["E4450","N6-Cyclopentyladenosine","e11","L4000-20","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","N6-Cyclopentyladenosine is an adenosine derivative and a potent adenosine receptor agonist with Ki values of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively. It acts as an anticonvulsant and might exhibit protective actions against aminophylline (AMPH)-induced seizures.",335.36,"41552-82-3",{"v":67,"d":"67.00"},199.79,{"v":4,"d":"4.00"},11.93,"https://www.selleckchem.com/products/n6-cyclopentyladenosine.html","C15H21N5O4","free base","N/A","OCC1OC(C(O)C1O)[N]2C=NC3=C(NC4CCCC4)N=CN=C23",0.077,4,4,4]
["E4477","Lumateperone","f11","L4000-20","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Lumateperone (ITI-007) is an antagonist of 5-HT2A receptor with Ki of 0.54 nM. It has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia.",{"v":393.5,"d":"393.50"},"313368-91-1",{"v":79,"d":"79.00"},200.76,"<1","N/A","https://www.selleckchem.com/products/lumateperone.html","C24H28FN3O","free base","ITI-007","CN1CCN2C3CCN(CCCC(=O)C4=CC=C(F)C=C4)CC3C5=CC=CC1=C25",3.765,1,0,5]
["S6952","MK-28","g11","L4000-20","in 10mM DMSO","PERK","Apoptosis","MK-28 is a potent and selective activator of PERK. MK-28 exhibits an IC50 ~3-fold higher than CCT020312 in rescuing mutant huntingtin protein (mHtt)-expressing striatal neurons from apoptosis. MK-28 exhibits remarkable pharmacokinetic properties and high BBB penetration in mice.",396.44,"864388-65-8",{"v":79,"d":"79.00"},199.27,"<1","N/A","https://www.selleckchem.com/products/mk-28.html","C24H20N4O2","free base","N/A","CN(\\N=C\\C1=CC(=C(O)C=C1)O)C2=NC(=CC(=N2)C3=CC=CC=C3)C4=CC=CC=C4",5.806,3,2,5]
["S7236","Cariprazine hydrochloride","h11","L4000-20","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Cariprazine hydrochloride(RGH188 hydrochloride) is a novel antipsychotic agent and is a highly selective partial agonist of dopamineD2 and D3 and 5HT1A receptors, with preferential binding to the D3 receptor. It exhibits high selectivity and affinity to dopamine D3 (Ki = 0.085 nM) and D2 (Ki = 0.49 nM) receptors and has moderate affinity for the 5-HT1A receptor (Ki = 2.6 nM).",463.87,"1083076-69-0",{"v":12,"d":"12.00"},25.87,"<1","N/A","https://www.selleckchem.com/products/cariprazine-rgh-188.html","C21H32Cl2N4O.HCl","hydrochloride","RGH188 hydrochloride","Cl.CN(C)C(=O)NC1CCC(CC1)CCN2CCN(CC2)C3=C(Cl)C(=CC=C3)Cl",4.934,1,1,5]
["S8395","INDY","a2","L4000-21","in 10mM DMSO","DYRK","Cell Cycle","INDY, a benzothiazole derivative is a potent and ATP-competitive inhibitor of Dyrk1A and Dyrk1B with an IC50 value of 0.24 μM and Ki value of 0.18 μM, respectively. INDY diminishes the self-renewal capacity of normal and tumorigenic cells in primary Glioblastoma (GBM) cell lines and neural progenitor cells.",{"v":235.3,"d":"235.30"},"1169755-45-6",{"v":47,"d":"47.00"},199.75,"<1","N/A","https://www.selleckchem.com/products/indy.html","C12H13NO2S","free base","N/A","CCN1/C(SC2=CC=C(O)C=C12)=C/C(C)=O",2.799,1,1,2]
["E1280","Ubrogepant","b2","L4000-21","in 10mM DMSO","CGRP Receptor","GPCR & G Protein","Ubrogepant (MK-1602) is an antagonist of human calcitonin gene-related peptide receptor (CGRP). It potently blocks human α–CGRP–stimulated cAMP responses with an IC50 of 0.081 nM in human CGRP receptor-expressing HEK293 cells.",549.54,"1374248-77-7",{"v":100,"d":"100.00"},181.97,"<1","N/A","https://www.selleckchem.com/products/ubrogepant.html","C29H26F3N5O3","free base","MK-1602","CC1C(CC(NC(=O)C2=CN=C3CC4(CC3=C2)C(=O)NC5=NC=CC=C45)C(=O)N1CC(F)(F)F)C6=CC=CC=C6",2.897,5,2,5]
["E1469","ITF3756","c2","L4000-21","in 10mM DMSO","HDAC6 selective inhibitors","DNA Damage/DNA Repair","ITF3756 is a selective histone deacetylase 6 (HDAC6) inhibitor bearing a pentaheterocyclic scaffold. It can be used in research of autoimmune disorders, neurodegenerative diseases, and cancer.",301.33,"2247608-27-9",{"v":60,"d":"60.00"},199.12,"<1","N/A","https://www.selleckchem.com/products/itf3756.html","C13H11N5O2S","free base","N/A","ONC(=O)C1=CC=C(C[N]2N=NN=C2C3=CC=CS3)C=C1",1.617,4,1,4]
["E4026","Poly(2-hydroxyethyl methacrylate)","d2","L4000-21","in 10mM DMSO","Others","Others","Poly(2-hydroxyethyl methacrylate) is one of the most important hydrogels in the world of biomaterials. It is the basic component of contact lenses and is also used in the implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of agents, etc.",130.14,"25249-16-5",{"v":100,"d":"100.00"},{"v":768.4,"d":"768.40"},"<1","N/A","https://www.selleckchem.com/products/poly-2-hydroxyethyl-methacrylate.html","(C6H10O3)x","free base","N/A","CC(=C)C(=O)OCCO",0.625,2,1,4]
["S1338","Gabapentin HCl","a2","L4000-22","in 10mM Water","GABA Receptor","Neuronal Signaling","Gabapentin HCl(Neurontin HCl) is a GABA analogue, used to treat seizures and neuropathic pain.",{"v":207.7,"d":"207.70"},"60142-95-2","<1","N/A",{"v":42,"d":"42.00"},202.21,"http://selleckchem.com/products/Gabapentin.html","C9H17NO2.HCl","Hydrochloride","Neurontin HCl","Cl.NCC1(CCCCC1)CC(O)=O",-1.104,1,1,3]
["S1339","Galanthamine HBr","b2","L4000-22","in 10mM Water","AChR,ADC Cytotoxin","Neuronal Signaling","Galanthamine is an AChE inhibitor with IC50 of 0.35 μM, exhibits 50-fold selectivity against butyryl-cholinesterase.",368.27,"1953-04-4","<1","N/A",{"v":36,"d":"36.00"},97.75,"http://selleckchem.com/products/Galanthamine-hydrobromide.html","C17H21NO3.HBr","Hydrobromide","N/A","Br.COC1=CC=C2CN(C)CCC34C=CC(O)CC3OC1=C24",1.933,2,1,1]
["S1345","Granisetron HCl","c2","L4000-22","in 10mM Water","5-HT Receptor","Neuronal Signaling","Granisetron is a serotonin 5-HT3 receptor antagonist,used to treat chemotherapy-induced nausea and vomiting.",348.87,"107007-99-8",{"v":1,"d":"1.00"},2.87,{"v":69,"d":"69.00"},197.78,"http://selleckchem.com/products/Granisetron-Hydrochloride.html","C18H24N4O.HCl","Hydrochloride","N/A","Cl.CN1C2CCCC1CC(C2)NC(=O)C3=N[N](C)C4=CC=CC=C34",2.783,2,1,2]
["S1375","Dorzolamide HCl","d2","L4000-22","in 10mM Water","Carbonic Anhydrase","Metabolism","Dorzolamide (MK-507, L-671152) HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent.",{"v":360.9,"d":"360.90"},"130693-82-2","<1","N/A",{"v":14,"d":"14.00"},38.79,"http://selleckchem.com/products/Dorzolamide-HCL.html","C10H16N2O4S3.HCl","Hydrochloride","MK-507 (L-671152) HCl","Cl.CCNC1CC(C)[S](=O)(=O)C2=C1C=C(S2)[S](N)(=O)=O",0.527,4,2,3]
["S1440","Varenicline Tartrate (CP 526555-18)","e2","L4000-22","in 10mM Water","AChR","Neuronal Signaling","Varenicline Tartrate (CP 526555-18, Chantix, Champix) is a nicotinic AChR partial agonist, used to treat nicotine addiction.",361.35,"375815-87-5",{"v":1,"d":"1.00"},2.77,{"v":72,"d":"72.00"},199.25,"http://selleckchem.com/products/Varenicline-tartrate.html","C13H13N3.C4H6O6","Tartrate","Chantix, Champix,CP 526555-18","OC(C(O)C(O)=O)C(O)=O.C1NCC2CC1C3=C2C=C4N=CC=NC4=C3",{"v":-3.33,"d":"-3.330"},4,3,3]
["S1506","Perindopril Erbumine","f2","L4000-22","in 10mM Water","RAAS","Endocrinology & Hormones","Perindopril Erbumine (S9490-3) is a pro-drug and metabolized in vivo by hydrolysis of the ester group to form Perindoprilat, the biologically active metabolite, a potent ACE inhibitor with IC50 of 1.05 nM. Perindopril Erbumine is used for in vivo studies and Perindoprilat is recommened for in vitro research.",{"v":441.6,"d":"441.60"},"107133-36-8","<1","N/A",{"v":88,"d":"88.00"},199.28,"http://selleckchem.com/products/Perindopril-Erbumine(Aceon).html","C19H32N2O5.C4H11N","t-Butylamine","S9490-3","CCCC(NC(C)C(=O)N1C2CCCCC2CC1C(O)=O)C(=O)OCC.CC(C)(C)N",0.016,4,2,9]
["S1518","Ibuprofen Lysine","g2","L4000-22","in 10mM Water","COX","Neuronal Signaling","Ibuprofen Lysine is a non-steroidal anti-inflammatory drug.",352.47,"57469-77-9","<1","N/A",{"v":71,"d":"71.00"},201.44,"http://selleckchem.com/products/Ibuprofen-Lysine(Motrin).html","C19H32N2O4","Lysine","N/A","CC(C)CC1=CC=C(C=C1)C(C)C(O)=O.NCCCCC(N)C(O)=O",-2.112,2,2,9]
["S1749","L-Glutamine","h2","L4000-22","in 10mM Water","Others","Others","L-Glutamine (Gln) is one of the 20 amino acids encoded by the standard genetic code and also a major respiratory fuel and substrate for nucleic acid synthesis in mammalian intestinal cells.",146.14,"56-85-9","<1","N/A",{"v":29,"d":"29.00"},198.44,"http://selleckchem.com/products/Glutamine.html","C5H10N2O3","free base","N/A","NC(CCC(N)=O)C(O)=O",-4.087,2,2,4]
["S1893","D-glutamine","a3","L4000-22","in 10mM Water","GluR","Neuronal Signaling","D-glutamine is a D type stereoisomer of glutamine which is one of the 20 amino acids encoded by the standard genetic code.",146.14,"5959-95-5","<1","N/A",{"v":9,"d":"9.00"},61.58,"http://selleckchem.com/products/D-glutamine.html","C5H10N2O3","free base","N/A","NC(CCC(N)=O)C(O)=O",-4.087,2,2,4]
["S1939","Levamisole hydrochloride","b3","L4000-22","in 10mM Water","Immunology & Inflammation related","Immunology & Inflammation","Levamisole, also known as (-)-Tetramisole, is an inhibitor of alkaline phosphatase, used as an anthelmintic.",240.75,"16595-80-5","<1","N/A",{"v":48,"d":"48.00"},199.38,"http://selleckchem.com/products/Levamisole-Hydrochloride(Ergamisol).html","C11H12N2S.HCl","Hydrochloride","(-)-Tetramisole hydrochloride","Cl.C1CN2CC(N=C2S1)C3=CC=CC=C3",2.672,1,0,1]
["S1984","Ticlopidine HCl","c3","L4000-22","in 10mM Water","P2 Receptor","Neuronal Signaling","Ticlopidine HCl is an P2 receptor inhibitor against ADP-induced platelet aggregation with IC50 of ~2 μM.",300.25,"53885-35-1",{"v":1,"d":"1.00"},3.33,{"v":4,"d":"4.00"},13.32,"http://selleckchem.com/products/ticlopidine-hydrochloride.html","C14H14ClNS.HCl","Hydrochloride","N/A","Cl.ClC1=C(CN2CCC3=C(C2)C=CS3)C=CC=C1",4.275,0,0,2]
["S1998","D-Cycloserine","d3","L4000-22","in 10mM Water","Antibiotics,Selection Antibiotics for Transfected Cell","Microbiology","D-cycloserine (RO-1-9213) is an analog of the amino acid D-alanine, used as an antibiotic in the treatment of tuberculosis.",102.09,"68-41-7","<1","N/A",{"v":20,"d":"20.00"},195.91,"http://selleckchem.com/products/D-Cycloserine.html","C3H6N2O2","free base","RO-1-9213","NC1CONC1=O",-1.788,2,2,0]
["S1999","Sodium butyrate","e3","L4000-22","in 10mM Water","Apoptosis related,Autophagy,HDAC","Epigenetics","Sodium butyrate (NaB, Butanoic acid sodium salt), sodium salt of butyric acid, is a histone deacetylase inhibitor and competitively binds to the zinc sites of class I and II histone deacetylases (HDACs). Sodium butyrate (NaB) inhibits cell cycle progression, promotes differentiation, and induces apoptosis and autophagy in several types of cancer cells.",110.09,"156-54-7","<1","N/A",{"v":22,"d":"22.00"},199.84,"http://selleckchem.com/products/Sodium-butyrate.html","C4H7NaO2","Sodium Salt","NaB, Butanoic acid sodium salt","[Na+].CCCC([O-])=O",-0.556,0,0,2]
["S2133","Gabapentin","f3","L4000-22","in 10mM Water","GABA Receptor","Neuronal Signaling","Gabapentin is a GABA analogue, used to treat seizures and neuropathic pain.",171.24,"60142-96-3","<1","N/A",{"v":34,"d":"34.00"},198.55,"http://selleckchem.com/products/Gabapentin(Neurontin).html","C9H17NO2","Free Base","N/A","NCC1(CCCCC1)CC(O)=O",-1.486,1,1,3]
["S2462","Donepezil HCl","g3","L4000-22","in 10mM Water","AChR","Neuronal Signaling","Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively.",{"v":416,"d":"416.00"},"120011-70-3","<1","N/A",{"v":5,"d":"5.00"},12.02,"http://selleckchem.com/products/Donepezil-hydrochloride(Aricept).html","C24H29NO3.HCl","Hydrochloride","N/A","Cl.COC1=C(OC)C=C2C(=O)C(CC3CCN(CC3)CC4=CC=CC=C4)CC2=C1",4.951,3,0,6]
["S2490","Neostigmine Bromide","h3","L4000-22","in 10mM Water","AChR","Neuronal Signaling","Neostigmine Bromide is a reversible acetylcholinesterase inhibitor.",{"v":303.2,"d":"303.20"},"114-80-7","<1","N/A",{"v":60,"d":"60.00"},197.89,"http://selleckchem.com/products/Neostigmine-bromide(Prostigmin).html","C12H19N2O2.Br","Bromide","N/A","[Br-].CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C",-1.907,2,0,3]
["S2507","Salbutamol Sulfate","a4","L4000-22","in 10mM Water","Adrenergic Receptor","Neuronal Signaling","Salbutamol Sulfate (Albuterol, Ventolin, Aerolin, Ventorlin, Asthalin, Asthavent) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 µM.",337.39,"51022-70-9","<1","N/A",{"v":68,"d":"68.00"},201.55,"http://selleckchem.com/products/Salbutamol-sulfate(Albuterol).html","C13H21NO3.H2SO4","Sulfate","Albuterol, Ventolin, Aerolin, Ventorlin, Asthalin, Asthavent","CC(C)(C)NCC(O)C1=CC=C(O)C(=C1)CO.O[S](O)(=O)=O",0.334,0,4,5]
["S2560","Amiloride HCl dihydrate","b4","L4000-22","in 10mM Water","Sodium Channel","Transmembrane Transporters","Amiloride HCl dihydrate(MK-870 hydrochloride dihydrate) is a potent epithelial sodium channel (ENaC) blocker, used in the management of hypertension and congestive heart failure.",302.12,"17440-83-4",{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},{"v":17,"d":"17.00"},56.27,"http://selleckchem.com/products/amilorida.html","C6H8ClN7O.HCl.2H2O","hydrochloride & dihydrate","MK-870 hydrochloride dihydrate","O.O.Cl.NC(=N)NC(=O)C1=NC(=C(N)N=C1N)Cl",{"v":-0.78,"d":"-0.780"},3,4,2]
["S2568","Neomycin sulfate","c4","L4000-22","in 10mM Water","Antibiotics,Antibiotics for Mammalian Cell Culture,Antineoplastic and Immunosuppressive Antibiotics,Bacterial,Selection Antibiotics for Transfected Cell","Microbiology","Neomycin sulfate(Framycin sulfate) is an aminoglycoside antibiotic, used to treat bacteria infections.",712.72,"28002-70-2 ,1405-10-3","<1","N/A",{"v":143,"d":"143.00"},200.64,"http://selleckchem.com/products/Neomycin-sulfate.html","C23H46N6O13.H2SO4","Sulfate","Framycin sulfate","NCC1OC(OC2C(N)CC(N)C(O)C2OC3OC(CO)C(OC4OC(CN)C(O)C(O)C4N)C3O)C(N)C(O)C1O.O[S](O)(=O)=O",-9.566,6,13,9]
["S3048","Solifenacin succinate","d4","L4000-22","in 10mM Water","AChR","Neuronal Signaling","Solifenacin succinate (YM905) is a urinary antispasmodic of the antimuscarinic class.",480.55,"242478-38-2",{"v":3,"d":"3.00"},6.24,{"v":96,"d":"96.00"},199.77,"http://selleckchem.com/products/solifenacin-succinate.html","C23H26N2O.C4H6O4","Succinate","YM905","OC(=O)CCC(O)=O.O=C(OC1CN2CCC1CC2)N3CCC4=C(C=CC=C4)C3C5=CC=CC=C5",0.635,4,0,6]
["S3050","Palonosetron HCl","e4","L4000-22","in 10mM Water","5-HT Receptor","Neuronal Signaling","Palonosetron HCl (RS 25259, RS 25259 197) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.",332.87,"135729-62-3","<1","N/A",{"v":67,"d":"67.00"},201.28,"http://selleckchem.com/products/palonosetron-hcl.html","C19H24N2O.HCl","HCL","RS 25259, RS 25259 197","Cl.O=C1N(CC2CCCC3=CC=CC1=C23)C4CN5CCC4CC5",3.127,1,0,1]
["S3072","(R)-baclofen","f4","L4000-22","in 10mM Water","GABA Receptor","Neuronal Signaling","(R)-baclofen (STX 209) is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.",213.66,"69308-37-8","<1","N/A",{"v":8,"d":"8.00"},37.44,"http://selleckchem.com/products/r-baclofen.html","C10H12ClNO2","free base","STX 209","NCC(CC(O)=O)C1=CC=C(Cl)C=C1",{"v":-1.06,"d":"-1.060"},1,1,4]
["S3146","Tripelennamine HCl","g4","L4000-22","in 10mM Water","Histamine Receptor","Neuronal Signaling","Tripelennamine (Pyribenzamine) is a widely used H1 antagonist, inhibiting PhIP glucuronidation with IC50 of 30 μM.",291.82,"154-69-8",{"v":2,"d":"2.00"},6.85,{"v":58,"d":"58.00"},198.75,"http://selleckchem.com/products/tripelennamine-hydrochloride.html","C16H21N3.HCl","HCl","Pyribenzamine HCl","Cl.CN(C)CCN(CC1=CC=CC=C1)C2=NC=CC=C2",3.484,1,0,6]
["S3662","Pirenzepine dihydrochloride","h4","L4000-22","in 10mM Water","AChR","Neuronal Signaling","Pirenzepine is an antimuscarinic agent which inhibits gastric acid secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular and urinary functions.",424.32,"29868-97-1",{"v":1,"d":"1.00"},2.36,{"v":84,"d":"84.00"},197.96,"http://selleckchem.com/products/pirenzepine-dihydrochloride.html","C19H21N5O2.2HCl","dihydrochloride","N/A","Cl.Cl.CN1CCN(CC1)CC(=O)N2C3=C(C=CC=C3)C(=O)NC4=CC=CN=C24",1.803,3,1,2]
["S3737","Cangrelor Tetrasodium","a5","L4000-22","in 10mM Water","P2 Receptor","Neuronal Signaling","Cangrelor (AR-C69931MX) is a potent, competitive P2Y12 receptor inhibitor that is administered by intravenous infusion and rapidly achieves near complete inhibition of ADP-induced platelet aggregation.",864.29,"163706-36-3",{"v":2,"d":"2.00"},2.31,{"v":100,"d":"100.00"},{"v":115.7,"d":"115.70"},"http://selleckchem.com/products/cangrelor-tetrasodium.html","21Cl2F3N5O12P3S2.4Na","tetrasodium salt","AR-C69931MX","CSCCNC1=NC(=NC2=C1N=C[N]2C3OC(CO[P](=O)(O[Na])O[P](=O)(O[Na])C(Cl)(Cl)[P](=O)(O[Na])O[Na])C(O)C3O)SCCC(F)(F)F",2.787,10,3,20]
["S3748","Acamprosate Calcium","b5","L4000-22","in 10mM Water","GABA Receptor","Transmembrane Transporters","Acamprosate (N-Acetylhomotaurine, Calcium acetylhomotaurinate,N-acetylhomotaurinate) is a synthetic compound with a chemical structure similar to the amino acid neurotransmitter gamma-aminobutyric acid (GABA) and the amino acid neuromodulator taurine.",200.24,"77337-73-6","<1","N/A",{"v":40,"d":"40.00"},199.76,"http://selleckchem.com/products/acamprosate-calcium.html","C5H11NO4S.1/2Ca","calcium salt","N-Acetylhomotaurine Calcium, calcium acetylhomotaurinate,N-acetylhomotaurinate","CC(=O)NCCC[S]([O-])(=O)=O",{"v":-2.67,"d":"-2.670"},1,1,4]
["S3852","L-Theanine","c5","L4000-22","in 10mM Water","Others","Others","L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation.",{"v":174.2,"d":"174.20"},"3081-61-6","<1","N/A",{"v":34,"d":"34.00"},195.18,"http://selleckchem.com/products/l-theanine.html","C7H14N2O3","free base","N/A","CCNC(=O)CCC(N)C(O)=O",{"v":0,"d":"0.000"},0,0,0]
["S3989","L-​Histidine","d5","L4000-22","in 10mM Water","Others","Others","L-​Histidine (Glyoxaline-5-alanine) is an α-amino acid needed in humans for growth and tissue repair. It is used in the biosynthesis of proteins.",155.15,"71-00-1","<1","N/A",{"v":31,"d":"31.00"},199.81,"https://www.selleckchem.com/products/l-histidine.html","C6H9N3O2","free base","Glyoxaline-5-alanine","NC(CC1=C[NH]C=N1)C(O)=O",{"v":0,"d":"0.000"},0,0,0]
["S4008","Pemirolast potassium","e5","L4000-22","in 10mM Water","Histamine Receptor","Neuronal Signaling","Pemirolast potassium (BMY26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.",{"v":266.3,"d":"266.30"},"100299-08-9","<1","N/A",{"v":53,"d":"53.00"},199.02,"http://selleckchem.com/products/pemirolast-bmy-26517-potassium.html","C10H7N6O.K","Potassium","BMY26517","[K+].CC1=CC=CN2C(=O)C(=CN=C12)C3=NN=N[N-]3",-1.246,5,0,1]
["S4027","Flavoxate HCl","f5","L4000-22","in 10mM Water","AChR","Neuronal Signaling","Flavoxate (NSC-114649) is a muscarinic AChR antagonist with IC50 of 12.2 μM.",427.92,"3717-88-2",{"v":3,"d":"3.00"},7.01,{"v":10,"d":"10.00"},23.37,"http://selleckchem.com/products/flavoxate-hcl.html","C24H25NO4.HCl","hydrochloride","NSC-114649","Cl.CC1=C(OC2=C(C=CC=C2C(=O)OCCN3CCCCC3)C1=O)C4=CC=CC=C4",4.876,4,0,6]
["S4028","Dexamethasone Sodium Phosphate","g5","L4000-22","in 10mM Water","Autophagy,Complement System,COVID-19,COX,IL Receptor","Immunology & Inflammation","Dexamethasone (Dexamethasone 21-phosphate disodium salt) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator  that has anti-inflammatory and immunosuppressant effects.",{"v":516.4,"d":"516.40"},"55203-24-2","<1","N/A",{"v":103,"d":"103.00"},199.46,"http://selleckchem.com/products/dexamethasone-sodium-phosphate.html","C22H30FO8P.2Na","Disodium salt","Dexamethasone 21-phosphate disodium salt","[Na+].[Na+].CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO[P]([O-])([O-])=O",-0.541,3,1,4]
["S4069","Hexamethonium Dibromide","h5","L4000-22","in 10mM Water","AChR","Neuronal Signaling","Hexamethonium Dibromide is a selective antagonist of neuronal-type nicotinic AChR in ganglia.",362.19,"55-97-0","<1","N/A",{"v":73,"d":"73.00"},201.55,"http://selleckchem.com/products/hexamethonium-bromide.html","C12H30N2.2Br","Bromide","N/A","[Br-].[Br-].C[N+](C)(C)CCCCCC[N+](C)(C)C",-5.532,0,0,7]
["S4117","Histamine Phosphate","a6","L4000-22","in 10mM Water","Histamine Receptor","Neuronal Signaling","Histamine(Histamine diphosphate) acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors.",307.14,"51-74-1","<1","N/A",{"v":42,"d":"42.00"},136.75,"http://selleckchem.com/products/histamine-phosphate.html","C5H9N.2H3O4P","Phosphate","Histamine diphosphate","NCCC1=C[NH]C=N1.O[P](O)(O)=O.O[P](O)(O)=O",-1.651,1,2,2]
["S4121","Succinylcholine Chloride Dihydrate","b6","L4000-22","in 10mM Water","AChR","Neuronal Signaling","Succinylcholine Chloride Dihydrate (Suxamethonium) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.",397.34,"6101-15-1",{"v":1,"d":"1.00"},2.52,{"v":79,"d":"79.00"},198.82,"http://selleckchem.com/products/succinylcholine-suxamethonium-chloride-dihydrate.html","C14H30N2O4.2Cl.2H2O","Chloride","Suxamethonium Chloride Dihydrate","O.O.[Cl-].[Cl-].C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C",-8.102,4,0,11]
["S4127","Terbutaline Sulfate","c6","L4000-22","in 10mM Water","Adrenergic Receptor","GPCR & G Protein","Terbutaline Sulfate(Terbutaline hemisulfate) is a selective β2-adrenergic receptor agonist with IC50 of 53 nM.",548.65,"23031-32-5","<1","N/A",{"v":100,"d":"100.00"},182.27,"http://selleckchem.com/products/terbutaline-sulfate.html","C24H38N2O6.H2SO4","Sulfate","Terbutaline hemisulfate","CC(C)(C)NCC(O)C1=CC(=CC(=C1)O)O.CC(C)(C)NCC(O)C2=CC(=CC(=C2)O)O.O[S](O)(=O)=O",2.001,0,8,8]
["S4137","Eprazinone 2HCl","d6","L4000-22","in 10mM Water","Others","Others","Eprazinone (NSC 317935) is a mucolytic.",453.44,"10402-53-6",{"v":1,"d":"1.00"},2.21,{"v":18,"d":"18.00"},{"v":39.7,"d":"39.70"},"http://selleckchem.com/products/eprazinone-2hcl.html","C24H32N2O2.2HCl","HCl","NSC 317935","Cl.Cl.CCOC(CN1CCN(CC1)CC(C)C(=O)C2=CC=CC=C2)C3=CC=CC=C3",4.838,2,0,9]
["S4180","Nefopam HCl","e6","L4000-22","in 10mM Water","Sodium Channel","Transmembrane Transporters","Nefopam HCl(Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline reuptake.",{"v":289.8,"d":"289.80"},"23327-57-3",{"v":1,"d":"1.00"},3.45,{"v":21,"d":"21.00"},72.46,"http://selleckchem.com/products/nefopam-hcl.html","C17H19NO.HCl","Hydrochloride","Fenazoxine hydrochloride","Cl.CN1CCOC(C2=CC=CC=C2)C3=C(C1)C=CC=C3",{"v":3.52,"d":"3.520"},1,0,1]
["S4328","Guanethidine Sulfate","f6","L4000-22","in 10mM Water","Others","Others","Guanethidine is an antihypertensive drug that reduces the release of catecholamines, such as norepinephrine.",{"v":494.7,"d":"494.70"},"60-02-6","N/A","N/A",{"v":10,"d":"10.00"},20.21,"http://selleckchem.com/products/guanethidine-sulfate.html","C20H44N8.H2O4S","Sulfate","N/A","NC(=N)NCCN1CCCCCCC1.NC(=N)NCCN2CCCCCCC2.O[S](O)(=O)=O","N/A","N/A","N/A","N/A"]
["S4360","Tolmetin Sodium","g6","L4000-22","in 10mM Water","COX","Immunology & Inflammation","Tolmetin(MCN2559) is a non-steroidal anti-inflammatory drug of the arylalkanoic acids. Tolmetin sodium dihydrate is a non-steroidal antiinflammatory agent, and acts as a non-selective COX inhibitor.",{"v":315.3,"d":"315.30"},"64490-92-2","<1",{"v":0,"d":"0.00"},{"v":63,"d":"63.00"},199.81,"http://www.selleckchem.com/products/tolmetin-sodium.html","C15H14NO3.Na.2H2O","sodium","MCN2559","O.O.C[N]1C(=CC=C1C(=O)C2=CC=C(C)C=C2)CC(=O)O[Na]",2.943,3,0,5]
["S4575","Pralidoxime chloride","h6","L4000-22","in 10mM Water","AChR","Neuronal Signaling","Pralidoxime chloride (2-PAM) is an antidote to organophosphate pesticides and chemicals; An acetylcholinesterase (AChE) reactivator.",172.61,"51-15-0","<1","N/A",{"v":34,"d":"34.00"},196.98,"http://selleckchem.com/products/pralidoxime-chloride.html","C7H9N2O.Cl","chloride","2-PAM (chloride)","[Cl-].C[N+]1=C(C=CC=C1)\\C=N\\O",-1.122,1,0,1]
["S4700","4-Aminobutyric acid (GABA)","a7","L4000-22","in 10mM Water","GABA Receptor","Neuronal Signaling","4-Aminobutyric acid (4-Aminobutanoic acid, GABA, Gamma-aminobutyric acid, Piperidic acid) is a naturally occurring neurotransmitter with central nervous system (CNS) inhibitory activity.",103.12,"56-12-2","<1","N/A",{"v":20,"d":"20.00"},193.95,"http://selleckchem.com/products/4-aminobutyric-acid.html","C4H9NO2","free base","4-Aminobutanoic acid, GABA, Gamma-aminobutyric acid, Piperidic acid","NCCCC(O)=O",-3.076,1,1,3]
["S4702","Sarcosine","b7","L4000-22","in 10mM Water","Amino acid transporter,GlyT,NMDAR","Neuronal Signaling","Sarcosine (N-methylglycine, Sarcosinic acid, Methylaminoacetic acid, Methylglycine) is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist.",89.09,"107-97-1","<1","N/A",{"v":17,"d":"17.00"},190.82,"http://selleckchem.com/products/sarcosine.html","C3H7NO2","free base","N-methylglycine, Sarcosinic acid, Methylaminoacetic acid, Methylglycine","CNCC(O)=O",-3.439,1,1,2]
["S4703","Choline bitartrate","c7","L4000-22","in 10mM Water","AChR","Neuronal Signaling","Choline bitartrate (2-hydroxyethyl(trimethyl)azanium, 2,3,4-trihydroxy-4-oxobutanoate) is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acetylcholine, a chemical that facilitates communication between the nerves and muscles.",253.25,"87-67-2","<1","N/A",{"v":50,"d":"50.00"},197.43,"http://selleckchem.com/products/choline-bitartrate.html","C5H14NO.C4H5O6","tartrate","2-hydroxyethyl(trimethyl)azanium;2,3,4-trihydroxy-4-oxobutanoate","C[N+](C)(C)CCO.OC(C(O)C([O-])=O)C(O)=O",-4.712,1,3,5]
["S4721","L-Glutamic acid monosodium salt","d7","L4000-22","in 10mM Water","GluR","Neuronal Signaling","L-Glutamic acid monosodium salt is the sodium salt of glutamic acid, found naturally in tomatoes, cheese and other foods.   L-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). (S)-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.",169.11,"142-47-2","<1","N/A",{"v":33,"d":"33.00"},195.14,"http://selleckchem.com/products/l-glutamic-acid-monosodium-salt.html","C5H8NO4.Na","sodium salt","Monosodium glutamate, MSG","NC(CCC(=O)O[Na])C(O)=O",-3.368,3,1,5]
["S4740","Sodium ferulate","e7","L4000-22","in 10mM Water","5-HT Receptor","Neuronal Signaling","Sodium ferulate (SF, Ferulic acid sodium salt), the sodium salt of ferulic acid, is a drug used in traditional Chinese medicine for treatment of cardiovascular and cerebrovascular diseases and to prevent thrombosis.",216.17,"24276-84-4",{"v":2,"d":"2.00"},9.25,{"v":43,"d":"43.00"},198.92,"http://selleckchem.com/products/ferulic-acid-sodium.html","C10H9O4.Na","Sodium salt","Ferulic acid sodium salt","[Na+].COC1=CC(=CC=C1O)\\C=C\\C([O-])=O",0.195,1,1,3]
["S4972","Choline Glycerophosphate","f7","L4000-22","in 10mM Water","Others","Others","Choline Glycerophosphate (Glycerophosphorylcholine) is a choline derivative and one of the two major forms of choline storage (along with phosphocholine) in the cytosol.",257.22,"28319-77-9",{"v":2,"d":"2.00"},7.78,{"v":51,"d":"51.00"},198.27,"http://selleckchem.com/products/choline-glycerophosphate.html","C8H20NO6P","Free Base","Glycerophosphorylcholine","C[N+](C)(C)CCO[P]([O-])(=O)OCC(O)CO",-4.131,2,2,8]
["S5097","Methotrexate disodium","g7","L4000-22","in 10mM Water","Dehydrogenase,DHFR","Metabolism","Methotrexate sodium, an inhibitor of tetrahydrofolate dehydrogenase, is an antineoplastic antimetabolite with immunosuppressant properties.",{"v":498.4,"d":"498.40"},"7413-34-5","<1","N/A",{"v":99,"d":"99.00"},198.64,"http://selleckchem.com/products/methotrexate-disodium.html","C20H20N8O5.2Na","disodium salt","N/A","[Na+].[Na+].CN(CC1=NC2=C(N)N=C(N)N=C2N=C1)C3=CC=C(C=C3)C(=O)NC(CCC([O-])=O)C([O-])=O",-2.834,5,3,9]
["S5131","Homotaurine","h7","L4000-22","in 10mM Water","GABA Receptor","Neuronal Signaling","Homotaurine (Tramiprosate, Alzhemed, 3-Amino-1-propanesulfonic acid) is a synthetic organic compound that has GABAergic activity by mimicking GABA. It is a GABAA partial agonist as well as a GABAB receptor partial agonist with low efficacy.",139.17,"3687-18-1","N/A","N/A",{"v":27,"d":"27.00"},194.01,"http://selleckchem.com/products/homotaurine.html","C3H9NO3S","free base","Tramiprosate, Alzhemed, 3-Amino-1-propanesulfonic acid","NCCC[S](O)(=O)=O",{"v":0,"d":"0.000"},0,0,0]
["S5137","O-Phospho-L-serine","a8","L4000-22","in 10mM Water","GluR","Neuronal Signaling","O-Phospho-L-serine (Dexfosfoserine), a molecule that mimics the phosphatidylserine head group and partially blocks microglial phagocytosis of apoptotic cells, is a specific group III metabotropic glutamate receptor (mGluR) agonist.",185.07,"407-41-0","<1","N/A",{"v":37,"d":"37.00"},199.92,"http://selleckchem.com/products/o-phospho-l-serine.html","C3H8NO6P","free base","Dexfosfoserine","NC(CO[P](O)(O)=O)C(O)=O",-4.121,2,1,4]
["S5252","Ozagrel sodium","b8","L4000-22","in 10mM Water","P450 (e.g. CYP17),Prostaglandin Receptor","Metabolism","Ozagrel sodium (KCT-0809, Cataclot, Xanbo) is a thromboxane A2 synthase (CYP5) inhibitor with neuroprotective properties.",250.23,"189224-26-8",{"v":1,"d":"1.00"},{"v":4,"d":"4.00"},{"v":50,"d":"50.00"},199.82,"http://selleckchem.com/products/ozagrel-sodium.html","C13H11N2O2.Na","sodium","KCT-0809, Cataclot, Xanbo","[Na+].[O-]C(=O)\\C=C\\C1=CC=C(C[N]2C=CN=C2)C=C1",{"v":0.13,"d":"0.130"},1,0,4]
["S5267","Nylidrin Hydrochloride","c8","L4000-22","in 10mM Water","Adrenergic Receptor","Neuronal Signaling","Nylidrin Hydrochloride (Buphenine), a β-adrenergic agonist, is used therapeutically for its vasodilating effect on the peripheral circulation and possibly on the cerebral circulation as well.",335.87,"849-55-8","N/A",{"v":0,"d":"0.00"},{"v":67,"d":"67.00"},199.48,"https://www.selleckchem.com/products/nylidrin-hydrochloride.html","C19H25NO2.HCl","hydrochloride","Buphenine HCl","Cl.CC(CCC1=CC=CC=C1)NC(C)C(O)C2=CC=C(O)C=C2",4.112,0,3,7]
["S5362","Citicoline","d8","L4000-22","in 10mM Water","Others","Others","Citicoline (CDP-choline, cytidine 5'-diphosphocholine) is a naturally occurring compound that acts as nutrient with a broad spectrum of benefits for conditions associated with symptoms of neurological dysfunction. As an endogenous compound, it is also an essential intermediate in the synthesis of cell membrane phospholipids and its formation is the rate-limiting step in phosphatidylcholine synthesis.",488.32,"987-78-0","<1","N/A",{"v":97,"d":"97.00"},198.64,"https://www.selleckchem.com/products/citicoline.html","C14H26N4O11P2","inner salt","CDP-choline, cytidine 5'-diphosphocholine","C[N+](C)(C)CCO[P]([O-])(=O)O[P](O)(=O)OCC1OC(C(O)C1O)N2C=CC(=NC2=O)N",-5.406,6,3,10]
["S5496","Guanethidine Monosulfate","e8","L4000-22","in 10mM Water","Adrenergic Receptor","Neuronal Signaling","Guanethidine monosulfate is an antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves.",296.39,"645-43-2","<1","N/A",{"v":59,"d":"59.00"},199.06,"http://selleckchem.com/products/guanethidine-monosulfate.html","C10H22N4.H2SO4","sulfate","N/A","NC(=N)NCCN1CCCCCCC1.O[S](O)(=O)=O",0.579,0,2,4]
["S5526","β-Alanine","f8","L4000-22","in 10mM Water","Others","Others","β-Alanine (beta-Alanine, 3-Aminopropanoic acid) is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotransmitter by activating glycine and GABA receptors.",89.09,"107-95-9","<1","N/A",{"v":17,"d":"17.00"},190.82,"http://www.selleckchem.com/products/beta-alanine.html","C3H7NO2","Free Base","beta-Alanine, 3-Aminopropanoic acid","NCCC(O)=O",-3.397,1,1,2]
["S5588","Creatine","g8","L4000-22","in 10mM Water","IFN,JAK","JAK/STAT","Creatine (Methylguanidoacetic acid) is a nitrogenous organic acid that occurs naturally in vertebrates. It facilitates the recycling of adenosine triphosphate (ATP) primarily in muscle and brain tissue.Creatine can inhibits the JAK-STAT1 signal transmission by inhibiting the interaction of IFN-γ receptors with JAK2 in an ATP-independent manner, thereby inhibiting downstream pro-inflammatory gene expression.",131.13,"57-00-1","<1","N/A",{"v":26,"d":"26.00"},198.28,"http://selleckchem.com/products/creatine.html","C4H9N3O2","free base","Methylguanidoacetic acid","CN(CC(O)=O)C(N)=N",-1.095,1,1,3]
["S5612","Isonipecotic acid","h8","L4000-22","in 10mM Water","GABA Receptor","Neuronal Signaling","Isonipecotic acid (4-Piperidinecarboxylic acid, 4-Carboxypiperidine, Hexahydroisonicotinic acid) is a heterocyclic compound that mainly acts as a GABAA receptor partial agonist.",129.16,"498-94-2",{"v":1,"d":"1.00"},7.74,{"v":26,"d":"26.00"},{"v":201.3,"d":"201.30"},"http://www.selleckchem.com/products/isonipecotic-acid.html","C6H11NO2","Free Base","4-Piperidinecarboxylic acid, 4-Carboxypiperidine, Hexahydroisonicotinic acid","OC(=O)C1CCNCC1",-2.819,1,1,1]
["S5632","L-aspartic Acid","a9","L4000-22","in 10mM Water","Others","Others","L-aspartic Acid is one of non-essential amino acids and may be a neurotransmitter.",{"v":133.1,"d":"133.10"},"56-84-8","<1","N/A",{"v":8,"d":"8.00"},60.11,"http://selleckchem.com/products/l-aspartic-acid.html","C4H7NO4","free base","N/A","NC(CC(O)=O)C(O)=O",{"v":-3.78,"d":"-3.780"},2,1,3]
["S5674","Lodoxamide Tromethamine","b9","L4000-22","in 10mM Water","Immunology & Inflammation related","Immunology & Inflammation","Lodoxamide Tromethamine (Alomide, Lodoxamidetromethamine) is the tromethamide salt form of lodoxamide, a synthetic mast cell stabilizing compound with anti-inflammatory activity.",{"v":553.9,"d":"553.90"},"63610-09-3","<1","N/A",{"v":19,"d":"19.00"},{"v":34.3,"d":"34.30"},"http://www.selleckchem.com/products/lodoxamide-tromethamine.html","C19H28ClN5O12","tromethamide salt","Alomide, Lodoxamidetromethamine","NC(CO)(CO)CO.NC(CO)(CO)CO.OC(=O)C(=O)NC1=C(Cl)C(=CC(=C1)C#N)NC(=O)C(O)=O",-9.554,4,10,10]
["S6023","Creatine monohydrate","c9","L4000-22","in 10mM Water","Others","Others","Creatine (Methylguanidoacetic acid) is a key player in the phosphagen energy system, the primary source of ATP during short-term, high intensity activities.",149.15,"6020-87-7","N/A","N/A",5.96,39.94,"http://www.selleck.cn/products/creatine-monohydrate.html","C4H11N3O3","monohydrate","Methylguanidoacetic acid monohydrate","O.CN(CC(O)=O)C(N)=N",-1.302,1,1,3]
["S6176","Scyllo-Inositol","d9","L4000-22","in 10mM Water","Others","Others","Scyllo-Inositol (Scyllitol, Cocositol, Quercinitol, AZD 103, Scyllo-Cyclohexanehexol) is a naturally occurring plant sugar alcohol found most abundantly in the coconut palm.",180.16,"488-59-5","N/A","N/A",9.03,50.11,"http://www.selleck.cn/products/scyllo-inositol.html","C6H12O6","free base","Scyllitol, Cocositol, Quercinitol, AZD 103, Scyllo-Cyclohexanehexol","OC1C(O)C(O)C(O)C(O)C1O",-3.065,0,6,0]
["S6224","(R)-Serine","e9","L4000-22","in 10mM Water","NMDAR","Neuronal Signaling","(R)-Serine is the R-enantiomer of serine, which is used in the biosynthesis of proteins. (R)-Serine acts as obligatory coagonist at the glycine site associated with the N-methyl-D-aspartate subtype of glutamate receptors (NMDAR) and has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration.",105.09,"312-84-5","N/A","N/A",21.02,{"v":200,"d":"200.00"},"http://www.selleck.cn/products/r-serine.html","C3H7NO3","free base","N/A","NC(CO)C(O)=O",-4.049,1,2,2]
["S6266","(S)-Glutamic acid","f9","L4000-22","in 10mM Water","GluR","Neuronal Signaling","(S)-Glutamic acid (L-Glutamic acid) is an endogenous, non-selective glutamate receptor agonist.",147.13,"56-86-0","N/A","N/A",{"v":4,"d":"4.00"},27.19,"http://www.selleck.cn/products/s-glutamic-acid.html","C5H9NO4","free base","L-Glutamic acid","NC(CCC(O)=O)C(O)=O",-3.459,2,1,4]
["S6592","Diquafosol Tetrasodium","g9","L4000-22","in 10mM Water","P2 Receptor","Neuronal Signaling","Diquafosol Tetrasodium (INS-365), a P2Y2 receptor agonist, is a pharmaceutical drug for the treatment of dry eye disease.",878.23,"211427-08-6","N/A","N/A",{"v":100,"d":"100.00"},113.87,"http://www.selleck.cn/products/diquafosol-tetrasodium.html","C18H22N4Na4O23P4","Tetrasodium","INS-365","[Na+].[Na+].[Na+].[Na+].OC1C(O)C(OC1CO[P]([O-])(=O)O[P]([O-])(=O)O[P]([O-])(=O)O[P]([O-])(=O)OCC2OC(C(O)C2O)N3C=CC(=O)NC3=O)N4C=CC(=O)NC4=O",-11.332,11,6,14]
["S7537","LB-100","h9","L4000-22","in 10mM Water","PP2A","PI3K/Akt/mTOR","LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.",268.31,"1026680-07-8","<1","N/A",{"v":53,"d":"53.00"},197.53,"http://selleckchem.com/products/lb-100.html","C13H20N2O4","free base","N/A","CN1CCN(CC1)C(=O)C2C3CCC(O3)C2C(O)=O",-3.624,3,0,2]
["S7548","Rilmenidine Phosphate","a10","L4000-22","in 10mM Water","Imidazoline Receptor","GPCR & G Protein","Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used for the treatment of hypertension.",278.24,"85409-38-7",{"v":1,"d":"1.00"},3.59,{"v":55,"d":"55.00"},197.67,"http://selleckchem.com/products/rilmenidine-phosphate.html","C10H19N2O5P","Phosphate","N/A","O[P](O)(O)=O.C1CN=C(NC(C2CC2)C3CC3)O1",1.296,2,1,4]
["P1017","Octreotide (SMS 201-995) acetate","b10","L4000-22","in 10mM Water","N/A","Neuronal Signaling","Octreotide (SMS 201-995) acetate is the acetate salt of a cyclic octapeptide. It is a long-acting octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin.","1019.28 (free base)","79517-01-4","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://selleckchem.com/products/octreotide-acetate.html","C49H66N10O10S2.xC2H4O2","Acetate","D-Phe-c[Cys-Phe-D-Trp-Lys-Thr-Cys]-Thr-ol","CC(O)C(CO)NC(=O)C1CSSCC(NC(=O)C(N)CC2=CC=CC=C2)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=C[NH]C5=C4C=CC=C5)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)N1",{"v":0,"d":"0.000"},0,0,0]
["P1030","Salmon Calcitonin Acetate","c10","L4000-22","in 10mM Water","N/A","N/A","Salmon Calcitonin Acetate, which is more potent and longer lasting than human CT, has been used widely for the treatment of osteoporosis, paget's disease, hypercalcemic shock and chronic pain in terminal cancer patients.",3431.85,"47931-85-1","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://www.selleckchem.com/peptide/salmon-calcitonin-acetate.html","C145H240N44O48S2","Acetate","N/A","CC(C)CC(NNC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)C(=O)C(CC1=CC=C(O)C=C1)NN2CCCC2C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)O)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CO)C(=O)NCC(=O)NC(C(C)O)C(=O)N3CCCC3C(N)=O)C(=O)C(=O)C(CCCCN)NC(=O)C(CC4=CN=C[NH]4)NC(=O)C(CC(C)C)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(N)=O)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(NC(=O)C5CSSCC(N)C(=O)NC(CO)C(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)N5)C(C)C",{"v":0,"d":"0.000"},0,0,0]
["P1049","GHRP-2","d10","L4000-22","in 10mM Water","N/A","N/A","GHRP-2 is a true hGH secretagogue. It is a synthetic agonist of ghrelin.",{"v":878,"d":"878.00"},"158861-67-7","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://selleckchem.com/products/GHRP-2-Acetate.html","C47H59N9O8","Free Base","N/A","CC(N)C(=O)NC(CC1=CC=C2C=CC=CC2=C1)C(=O)NC(CC3=C[NH]C4=C3C=CC=C4)C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCCCN)C(N)=O",{"v":0,"d":"0.000"},0,0,0]
["P1085","Angiotensin II human Acetate","e10","L4000-22","in 10mM Water","Angiotensin Receptor","GPCR & G Protein","Angiotensin II (angII) is an octapeptide hormone which affects the activities of heart, kidney, vasculature and brain. It works via binding to specific receptors present on cell membranes.",1106.23,"68521-88-0","N/A","N/A","N/A",{"v":10,"d":"10.00"},"https://www.selleckchem.com/products/angiotensin-ii-human-acetate.html","C52H75N13O14","Acetate","N/A","CCC(C)C(NC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C(NC(=O)C(CCCNC(N)=N)NC(=O)C(N)CC(O)=O)C(C)C)C(=O)NC(CC2=C[NH]C=N2)C(=O)N3CCCC3C(=O)NC(CC4=CC=CC=C4)C(O)=O.CC(O)=O",{"v":0,"d":"0.000"},0,0,0]
["S4933","Lithium carbonate","f10","L4000-22","in 10mM Water","Dopamine Receptor","Neuronal Signaling","Lithium carbonate (Li2CO3) is an inorganic compound that is valuable and effective agent in the treatment and prophylaxis of mood disorders, particularly bipolar disorder (BD). Lithium carbonate is able to alter D2 dopamine receptors response.",73.89,"554-13-2","N/A","N/A","N/A",{"v":10,"d":"10.00"},"https://www.selleckchem.com/products/lithium-carbonate.html","CLi2O3","Salt","Li2CO3","[LiH].[Li]OOC=O",-0.347,2,0,2]
["S3203","D-Alanine","g10","L4000-22","in 10mM Water","NMDAR","Neuronal Signaling","D-alanine (Ala, (R)-Alanine, Ba 2776, D-α-Alanine, NSC 158286) is an endogenous co-agonist at the glycine site of the N-methyl-d-aspartate (NMDA) receptor.",89.09,"338-69-2","<1","N/A",{"v":18,"d":"18.00"},202.04,"http://www.selleckchem.com/products/d-alanine.html","C3H7NO2","free base","Ala, (R)-Alanine, Ba 2776, D-α-Alanine, NSC 158286","CC(N)C(O)=O",-3.161,1,1,1]
["P1088","Lanreotide acetate","h10","L4000-22","in 10mM Water","GHSR","Endocrinology & Hormones","Lanreotide (Laromustine, Angiopeptin, BIM 23014, Dermopeptin, Ipstyl, ITM-014, Somatulina, Somatuline, Lanreotidum) acetate, an analog of the native somatostatin peptide, is a physiological inhibitor of growth hormone (GH). Lanreotide also has antitumoral effects.",1156.38,"2378114-72-6",{"v":-1,"d":"-1.00"},"N/A",{"v":23,"d":"23.00"},19.89,"https://www.selleckchem.com/products/lanreotide-acetate.html","C56H73N11O12S2","Acetate","Laromustine, Angiopeptin, BIM 23014, BIM 23014C, BM 23014, Dermopeptin, Ipstyl, ITM-014, ITM-014T, Somatulina, Somatuline, Lanreotidum","CC(C)C1NC(=O)C(CCCCN)NC(=O)C(CC2=C[NH]C3=C2C=CC=C3)NC(=O)C(CC4=CC=C(O)C=C4)NC(=O)C(CSSCC(NC1=O)C(=O)NC(C(C)O)C(N)=O)NC(=O)C(N)CC5=CC6=CC=CC=C6C=C5.CC(O)=O",-0.979,9,13,17]
["S2996","L-DAB HBR","a11","L4000-22","in 10mM Water","GABA Receptor","Neuronal Signaling","L-DAB HBR (L-Dab Hydrobromide, L-2,4-Diaminobutyric acid hydrobromide) is an inhibitor of GABA (Gamma-aminobutyric acid) transaminase with IC50 of >500 μM. L-DAB HBR exhibits antitumor activity.",199.05,"73143-97-2","<1","N/A",{"v":23,"d":"23.00"},{"v":194.7,"d":"194.70"},"https://www.selleckchem.com/products/ldab-hbr.html","C4H11BrN2O2","Hydrobromide","L-Dab Hydrobromide, L-2,4-Diaminobutyric acid hydrobromide","Br.NCCC(N)C(O)=O",-3.786,1,2,3]
["S3326","Phytic acid dipotassium salt","b11","L4000-22","in 10mM Water","BACE","Neuronal Signaling","Phytic acid dipotassium salt (Phytic acid potassium, IP6 (PS)), an endogenous metabolite in rice grain extract and digest, inhibits β-secretase 1 (BACE1) with IC50 of approximately 0.25 μM.",736.22,"129832-03-7","<1","N/A",{"v":100,"d":"100.00"},135.83,"https://www.selleckchem.com/products/phytic-acid-dipotassium-salt.html","C6H16K2O24P6","Dipotassium salt","Phytic acid potassium, IP6 (PS)","[K+].[K+].O[P](O)(=O)OC1C(O[P](O)(O)=O)C(O[P](O)(O)=O)C(O[P]([O-])([O-])=O)C(O[P](O)(O)=O)C1O[P](O)(O)=O",-5.671,6,0,12]
["S3346","1-Methylnicotinamide chloride","c11","L4000-22","in 10mM Water","Prostaglandin Receptor","GPCR & G Protein","1-Methylnicotinamide (1-MNA, 3-Carbamoyl-1-methylpyridin-1-ium, Trigonellamide) chloride is an active endogenous metabolite of nicotinamide that exhibits anti-inflammatory and anti-thrombotic activities. 1-Methylnicotinamide enhances tumor vasculature formation and markedly increases prostacyclin (PGI2) generation.",172.61,"1005-24-9","<1","N/A",{"v":35,"d":"35.00"},202.77,"https://www.selleckchem.com/products/1-methylnicotinamide-chloride.html","C7H9ClN2O","Chloride","1-MNA, 3-Carbamoyl-1-methylpyridin-1-ium chloride, Trigonellamide chloride","[Cl-].C[N+]1=CC=CC(=C1)C(N)=O",-2.237,1,1,1]
["S3368","Uridine-5'-diphosphate disodium salt","d11","L4000-22","in 10mM Water","P2 Receptor","Neuronal Signaling","Uridine-5'-diphosphate (UDP) disodium salt is a potent, selective and natural agonist of P2Y6 receptor with EC50 = 300 nM and pEC50 of 6.52, respectively. Uridine-5'-diphosphate (UDP) disodium salt is also an antagonist of P2Y14 receptor with pEC50 of 7.28.",448.12,"27821-45-0","<1","N/A",{"v":90,"d":"90.00"},200.84,"https://www.selleckchem.com/products/uridine-5-diphosphate-disodium-salt.html","C9H12N2Na2O12P2","Disodium salt","UDP disodium salt","[Na+].[Na+].OC1C(O)C(OC1CO[P]([O-])(=O)O[P](O)([O-])=O)N2C=CC(=O)NC2=O",-5.757,5,3,6]
["S9664","Colivelin","e11","L4000-22","in 10mM Water","Beta Amyloid,STAT","JAK/STAT","Colivelin (CLN) is a brain-penetrant neuroprotective peptide with potent long-term capacity against Aβ deposition, neuronal apoptosis, and synaptic plasticity deficits in neurodegenerative disease. Colivelin is an activator of STAT3.",{"v":2645.1,"d":"2645.10"},"867021-83-8",{"v":-1,"d":"-1.00"},"N/A",{"v":100,"d":"100.00"},37.81,"https://www.selleckchem.com/products/colivelin.html","C119H206N32O35","Free Base","CLN","CCC(C)C(NC(=O)C(CCC(O)=O)NC(=O)CNC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(N)=N)NC(=O)C(CO)NC(=O)C(C)NC(=O)CNC(=O)C(C)NC(=O)C1CCCN1C(=O)C(C)NC(=O)C2CCCN2C(=O)C(NC(=O)C(CO)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(N)CO)C(C)CC)C(C)O)C(=O)NC(CC(O)=O)C(=O)NC(CC(C)C)C(=O)N3CCCC3C(O)=O",-8.786,28,31,85]
["S4494","Methionine","f11","L4000-22","in 10mM Water","GABA Receptor","Neuronal Signaling","Methionine (MRX-1024, D-Methionine) is an activitor of GABAA receptor that modulates neuronal activity.",149.21,"348-67-4","<1","N/A",{"v":29,"d":"29.00"},194.36,"http://www.selleckchem.com/products/methionine.html","C5H11NO2S","Free Base","MRX-1024, D-Methionine","CSCCC(N)C(O)=O",-2.834,1,1,4]
["S5022","Varenicline Hydrochloride","g11","L4000-22","in 10mM Water","AChR","Neuronal Signaling","Varenicline (CP 526555) Hydrochloride is a potent and selective inhibitor of nicotine acetylcholine receptor (nAChR) with Ki of 0.12 nM and 0.14 nM for α6β2 nAChR and α4β2 nAChR, respectively.",247.72,"230615-23-3","<1","N/A",{"v":50,"d":"50.00"},201.84,"http://www.selleckchem.com/products/varenicline-hydrochloride.html","C13H14ClN3","Hydrochloride","CP 526555 hydrochloride","Cl.C1NCC2CC1C3=CC4=NC=CN=C4C=C23",{"v":1.42,"d":"1.420"},2,1,0]
["S5956","Dexamethasone phosphate disodium","h11","L4000-22","in 10mM Water","Glucocorticoid Receptor","Endocrinology & Hormones","Dexamethasone phosphate disodium (DEX, Dexacort, Decadron, Dexair, Hexadrol, Maxidex) is a glucocorticoid receptor agonist with both anti-inflammatory and anti-oxidative effects.",{"v":516.4,"d":"516.40"},"2392-39-4","<1","N/A",{"v":100,"d":"100.00"},193.65,"http://www.selleckchem.com/products/dexamethasone-phosphate-disodium.html","C22H28FNa2O8P","Disodium","DEX, Dexacort, Decadron, Dexair, Hexadrol, Maxidex, Dexamethasone 21-phosphate disodium salt","[Na+].[Na+].CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO[P]([O-])([O-])=O",-0.541,3,1,4]
["S9820","Angiotensin (1-7)","a2","L4000-23","in 10mM Water","ACE,RAAS","Endocrinology & Hormones","Angiotensin (1-7) (Ang-(1-7), Angiotensin fragment 1-7) is a bioactive component of the renin-angiotensin system that is formed endogenously from either Ang I or Ang II. Angiotensin (1-7) is a canine ACE inhibitor with an IC50 of 0.65 μM and inhibits the activity mediated by myostatin through Mas receptor.",{"v":899,"d":"899.00"},"51833-78-4","<1","N/A",{"v":50,"d":"50.00"},55.62,"http://www.selleckchem.com/products/angiotensin-1-7.html","C41H62N12O11","Free Base","Ang-(1-7), Angiotensin fragment 1-7","CCC(C)C(NC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C(NC(=O)C(CCCN=C(N)N)NC(=O)C(N)CC(O)=O)C(C)C)C(=O)NC(CC2=CN=C[NH]2)C(=O)N3CCCC3C(O)=O",{"v":-3.96,"d":"-3.960"},10,10,25]
["E2691","BAPTA tetrapotassium salt","b2","L4000-23","in 10mM Water","Calcium Channel","Transmembrane Transporters","BAPTA tetrapotassium salt (BAPTA tetrapotassium) is a non-permeable, selective extracellular calcium chelator, with 105-fold greater affinity for Ca2+ than Mg2+, which is a valuable tool to study the role of calcium in cell signaling.",632.83,"73630-08-7","<1","N/A",{"v":100,"d":"100.00"},158.02,"http://www.selleckchem.com/products/bapta-tetrapotassium-salt-e2691.html","C22H24N2O10.4K","tetrapotassium salt","BAPTA tetrapotassium","[K+].[K+].[K+].[K+].[O-]C(=O)CN(CC([O-])=O)C1=C(OCCOC2=C(C=CC=C2)N(CC([O-])=O)CC([O-])=O)C=CC=C1",{"v":-4.2,"d":"-4.200"},2,0,15]
["S8416","PACAP 6-38","c2","L4000-23","in 10mM Water","cAMP","GPCR & G Protein","PACAP 6-38 is a PACAP (pituitary adenylate cyclase-activating polypeptide) non-stimulating competitive antagonist with an IC50 value of 2 nM. It also acts as a functional CARTp antagonist in vivo.",4024.74,"143748-18-9","<1","N/A",{"v":100,"d":"100.00"},24.85,"http://www.selleckchem.com/products/pacap-6-38.html","C182H300N56O45S","Free base","N/A","CSCCC(NC(=O)C(CCC(N)=O)NC(=O)C(CCCCN)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C(CCCNC(N)=N)NC(=O)C(CO)NC(=O)C(CC2=CC=C(O)C=C2)NC(=O)C(CO)NC(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(N)CC3=CC=CC=C3)C(C)O)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC4=CC=C(O)C=C4)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC5=CC=C(O)C=C5)C(=O)NC(CCCCN)C(=O)NC(CCC(N)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(N)=O)C(=O)NC(CCCCN)C(N)=O",{"v":-15.97,"d":"-15.970"},37,59,146]
["E1246","D-AP5","d2","L4000-23","in 10mM Water","NMDAR","Neuronal Signaling","D-AP5 (D-APV; D-2-Amino-5-phosphonovaleric acid) is a selective and competitive NMDA receptor antagonist that inhibits the glutamate binding site of NMDA receptors.",197.13,"79055-68-8","<1","N/A",{"v":39,"d":"39.00"},197.84,"https://www.selleckchem.com/products/d-ap5.html","C5H12NO5P","Free base","N/A","NC(CCC[P](O)(O)=O)C(O)=O",-3.632,1,1,5]
["E2979","DL-AP5 (2-APV)","e2","L4000-23","in 10mM Water","NMDAR","Neuronal Signaling","DL-AP5 (2-APV, DL-2-Amino-5-phosphonovaleric acid) is a competitive antagonist of NMDA (N-methyl-D-aspartate) receptor. It shows significantly antinociceptive activity and specifically blocks on channels in the rabbit retina.",197.13,"76326-31-3","<1","N/A",{"v":39,"d":"39.00"},197.84,"https://www.selleckchem.com/products/dl-ap5-2-apv.html","C5H12NO5P","Free base","DL-2-Amino-5-phosphonovaleric acid","NC(CCC[P](O)(O)=O)C(O)=O",-3.632,1,1,5]
["S1424","Prazosin HCl","a2","L4000-24","in 2mM DMSO","Adrenergic Receptor","GPCR & G Protein","Prazosin HCl (cp-12299-1) is a competitive alpha-1 adrenoceptor antagonist, used to treat high blood pressure or benign prostatic hyperplasia.",419.86,"19237-84-4",{"v":4,"d":"4.00"},9.53,"<1","N/A","http://selleckchem.com/products/Prazosin-hydrochloride.html","C19H21N5O4.HCl","Hydrochloride","cp-12299-1","Cl.COC1=CC2=C(C=C1OC)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N",2.489,6,1,4]
["S1507","Irbesartan","b2","L4000-24","in 2mM DMSO","Angiotensin Receptor","GPCR & G Protein","Irbesartan (BMS-186295, SR-47436,APROVEL) is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM.",428.53,"138402-11-6",{"v":4,"d":"4.00"},9.33,"<1","N/A","http://selleckchem.com/products/Irbesartan(Avapro).html","C25H28N6O","free base","BMS-186295, SR-47436,APROVEL","CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=N[NH]N=N5",{"v":0,"d":"0.000"},0,0,0]
["S1615","Risperidone","c2","L4000-24","in 2mM DMSO","5-HT Receptor","Neuronal Signaling","Risperidone (R-64766) is a mutil-targeted antagonist for dopamine, serotonin, adrenergic and histamine receptors, used to treat schizophrenia and bipolar disorder.",410.48,"106266-06-2",{"v":4,"d":"4.00"},9.74,"<1","N/A","http://selleckchem.com/products/Risperidone(Risperdal).html","C23H27FN4O2","free base","R-64766","CC1=C(CCN2CCC(CC2)C3=NOC4=C3C=CC(=C4)F)C(=O)N5CCCCC5=N1",3.317,4,0,4]
["S1642","Methyldopa","d2","L4000-24","in 2mM DMSO","5-HT Receptor,Adrenergic Receptor,Decarboxylase,Dopamine Receptor","Metabolism","Methyldopa (Aldomet) is a DOPA decarboxylase competitive inhibitor with an ED50 of 21.8 mg/kg.",211.21,"555-30-6",{"v":2,"d":"2.00"},9.47,"<1","N/A","http://selleckchem.com/products/Methyldopa(Aldomet).html","C10H13NO4","free base","N/A","CC(N)(CC1=CC(=C(O)C=C1)O)C(O)=O",{"v":0,"d":"0.000"},0,0,0]
["S1707","Eplerenone (CGP 30083)","e2","L4000-24","in 2mM DMSO","Mineralocorticoid Receptor","Endocrinology & Hormones","Eplerenone (CGP 30083, SC-66110) is a mineralocorticoid receptor antagonist, and blocks the action of aldosterone, used to control high blood pressure.",414.49,"107724-20-9",{"v":4,"d":"4.00"},9.65,"<1","N/A","http://selleckchem.com/products/Eplerenone(Inspra).html","C24H30O6","free base","CGP 30083, SC-66110","COC(=O)C1CC2=CC(=O)CCC2(C)C34OC3CC5(C)C(CCC56CCC(=O)O6)C14",{"v":0,"d":"0.000"},0,0,0]
["S1724","Paliperidone","f2","L4000-24","in 2mM DMSO","Dopamine Receptor","Neuronal Signaling","Paliperidone, the main active metabolite of Risperidone, is a potent serotonin-2A and dopamine-2 receptor antagonist, used in the treatment of schizophrenia.",426.48,"144598-75-4",{"v":4,"d":"4.00"},9.38,"<1","N/A","http://selleckchem.com/products/Paliperidone(Invega).html","C23H27FN4O3","free base","N/A","CC1=C(CCN2CCC(CC2)C3=NOC4=C3C=CC(=C4)F)C(=O)N5CCCC(O)C5=N1",{"v":0,"d":"0.000"},0,0,0]
["S1929","Irsogladine","g2","L4000-24","in 2mM DMSO","AChR,PDE","Metabolism","Irsogladine(Dicloguamine) is an anti-gastric ulcer agent that facilitates gap-junctional intercellular communication through M1 muscarininc acetylcholine receptor binding.",256.09,"57381-26-7",{"v":2,"d":"2.00"},7.81,"<1","N/A","http://selleckchem.com/products/Irsogladine-maleate.html","C9H7Cl2N5","free base","Dicloguamine","NC1=NC(=NC(=N1)C2=C(Cl)C=CC(=C2)Cl)N",2.443,3,2,1]
["S1986","Meclizine 2HCl","h2","L4000-24","in 2mM DMSO","CAR,Histamine Receptor","Neuronal Signaling","Meclizine (NSC 28728,Meclozine dihydrochloride) is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation properties, also an agonist ligand for mCAR (constitutive androstane receptor) and an inverse agonist for hCAR.",463.87,"1104-22-9",{"v":4,"d":"4.00"},8.62,"<1","N/A","http://selleckchem.com/products/meclizine-dihydrochloride.html","C25H27Cl2N2.2HCl","Dihydrochloride","NSC 28728,Meclozine dihydrochloride","Cl.Cl.CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(Cl)C=C4",{"v":0,"d":"0.000"},0,0,0]
["S2035","Epalrestat (ONO-2235)","a3","L4000-24","in 2mM DMSO","Aldose Reductase,Carbohydrate Metabolism","Metabolism","Epalrestat (ONO-2235) is an aldose reductase inhibitor with IC50 of 72 nM.",{"v":319.4,"d":"319.40"},"82159-09-9",{"v":3,"d":"3.00"},9.39,"<1","N/A","http://selleckchem.com/products/epalrestat.html","C15H13NO3S2","free base","ONO-2235","CC(=C/C1=CC=CC=C1)\\C=C2/SC(=S)N(CC(O)=O)C2=O",3.442,2,0,4]
["S2047","Lornoxicam","b3","L4000-24","in 2mM DMSO","COX","Neuronal Signaling","Lornoxicam (Chlortenoxicam) is a non-steroidal COX-1/COX-2 inhibitor, used as an anti-inflammatory drug to treat pain, osteoarthritis, and rheumatoid arthritis.",371.82,"70374-39-9",{"v":3,"d":"3.00"},8.07,"<1","N/A","http://selleckchem.com/products/lornoxicam-xefo.html","C13H10ClN3O4S2","free base","Chlortenoxicam","CN1C(=C(O)C2=C(C=C(Cl)S2)[S]1(=O)=O)C(=O)NC3=NC=CC=C3",0.913,4,2,2]
["S2110","Vinpocetine","c3","L4000-24","in 2mM DMSO","Sodium Channel","Transmembrane Transporters","Vinpocetine (RGH-4405,Ethyl apovincaminate,AY 27255) is a selective inhibitor of voltage-sensitive sodium channel for the treatment of stroke, vascular dementia  and Alzheimer's disease.",350.45,"42971-09-5",{"v":3,"d":"3.00"},8.56,"<1","N/A","http://selleckchem.com/products/vinpocetine-cavinton.html","C22H26N2O2","free base","RGH-4405,Ethyl apovincaminate,AY 27255","CCOC(=O)C1=CC2(CC)CCCN3CCC4=C(C23)[N]1C5=CC=CC=C45",{"v":0,"d":"0.000"},0,0,0]
["S2232","Ketanserin","d3","L4000-24","in 2mM DMSO","5-HT Receptor","Neuronal Signaling","Ketanserin (R41468, Ketanserinum) is a specific 5-HT2A serotonin receptor antagonist with Ki of 2.5 nM for rat and human 5-HT2A, used as an antihypertensive drug.",395.43,"74050-98-9",{"v":2,"d":"2.00"},5.06,"<1","N/A","http://selleckchem.com/products/Ketanserin-Vulketan-Gel.html","C22H22FN3O3","Free Base","R41468, Ketanserinum","FC1=CC=C(C=C1)C(=O)C2CCN(CC2)CCN3C(=O)NC4=CC=CC=C4C3=O",2.991,3,1,5]
["S2251","(-)-Huperzine A (HupA)","e3","L4000-24","in 2mM DMSO","AChR,GluR","Neuronal Signaling","(-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4.",242.32,"102518-79-6",0.66,2.72,"<1","N/A","http://selleckchem.com/products/(-)-Huperzine-A.html","C15H18N2O","Free Base","N/A","C\\C=C/1C2CC3=C(C=CC(=O)N3)C1(N)CC(=C2)C",1.056,1,2,0]
["S2582","Trazodone HCl","f3","L4000-24","in 2mM DMSO","5-HT Receptor","Neuronal Signaling","Trazodone HCl (AF-1161, KB-831) is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.",408.32,"25332-39-2",{"v":4,"d":"4.00"},{"v":9.8,"d":"9.80"},"<1","N/A","http://selleckchem.com/products/trazodone-hydrochloride-desyrel.html","C19H22ClN5O.HCl","Hydrochloride","AF-1161, KB-831","Cl.ClC1=CC(=CC=C1)N2CCN(CCCN3N=C4C=CC=CN4C3=O)CC2",{"v":0,"d":"0.000"},0,0,0]
["S3041","Droxidopa","g3","L4000-24","in 2mM DMSO","Adrenergic Receptor","GPCR & G Protein","Droxidopa (L-DOPS) is a psychoactive drug and acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline).",213.19,"23651-95-8",{"v":2,"d":"2.00"},9.38,{"v":1,"d":"1.00"},4.69,"http://www.selleck.cn/products/droxidopa-l-dops.html","C9H11NO5","Free Base","L-DOPS","NC(C(O)C1=CC(=C(O)C=C1)O)C(O)=O",-2.921,1,4,3]
["S3064","Ambroxol HCl","h3","L4000-24","in 2mM DMSO","Sodium Channel","Transmembrane Transporters","AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. Phase 3.",414.56,"23828-92-4",{"v":4,"d":"4.00"},9.65,"<1","N/A","http://selleckchem.com/products/ambroxol-hcl.html","C13H18Br2N2O.HCl","Hydrochloride","N/A","Cl.NC1=C(Br)C=C(Br)C=C1CNC2CCC(O)CC2",3.121,0,3,3]
["S3721","Bilastine","a4","L4000-24","in 2mM DMSO","Histamine Receptor","Neuronal Signaling","Bilastine is a new, well-tolerated, nonsedating H1 receptor antihistamine and has a rapid onset and prolonged duration of action.",463.61,"202189-78-4",{"v":1,"d":"1.00"},2.16,"<1","N/A","http://selleckchem.com/products/bilastine.html","C28H37N3O3","free base","N/A","CCOCC[N]1C(=NC2=C1C=CC=C2)C3CCN(CC3)CCC4=CC=C(C=C4)C(C)(C)C(O)=O",{"v":2.07,"d":"2.070"},3,0,10]
["S3821","Nuciferine","b4","L4000-24","in 2mM DMSO","5-HT Receptor,5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Nuciferine (Sanjoinine E, (-)-Nuciferine, VLT 049) is a major active aporphine alkaloid from the leaves of N. nucifera Gaertn and possesses anti-hyperlipidemia, anti-hypotensive, anti-arrhythmic, and insulin secretagogue activities. Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 μM) and 5-HT6 (EC50=700 nM), an agonist at 5-HT1A (EC50=3.2 μM) and D4 (EC50=2 μM) receptor.",295.38,"475-83-2",{"v":2,"d":"2.00"},6.77,"<1","N/A","http://selleckchem.com/products/nuciferine.html","C19H21NO2","free base","Sanjoinine E, (-)-Nuciferine, VLT 049","COC1=C(OC)C2=C3C(CC4=C2C=CC=C4)N(C)CCC3=C1",3.567,2,0,2]
["S4033","Sennoside A","c4","L4000-24","in 2mM DMSO","MAO","Metabolism","Sennoside A (NSC 112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.",862.74,"81-27-6","N/A",{"v":2,"d":"2.00"},"<1","N/A","http://selleckchem.com/products/sennoside-a.html","C42H38O20","Free Base","NSC 112929","OCC1OC(OC2=CC=CC3=C2C(=O)C4=C(O)C=C(C=C4C3C5C6=C(C(=O)C7=C(O)C=C(C=C57)C(O)=O)C(=CC=C6)OC8OC(CO)C(O)C(O)C8O)C(O)=O)C(O)C(O)C1O",0.409,8,10,9]
["S4218","Amoxapine","d4","L4000-24","in 2mM DMSO","Amino acid transporter,GlyT","Neuronal Signaling","Amoxapine (CL 67772,Asendin) is a tricyclic dibenzoxazepine (an N-aryl piperazine) which acts similarly to several other tricyclic antidepressants, amoxapine inhibits GLYT2a transport activity with IC50 of 92 μM.",313.78,"14028-44-5",{"v":3,"d":"3.00"},9.56,"<1","N/A","http://selleckchem.com/products/amoxapine.html","C17H16ClN3O","free base","CL 67772,Asendin","ClC1=CC2=C(OC3=C(C=CC=C3)N=C2N4CCNCC4)C=C1",{"v":0,"d":"0.000"},0,0,0]
["S4262","Ebastine","e4","L4000-24","in 2mM DMSO","Histamine Receptor","Neuronal Signaling","Ebastine(LAS-W 090,RP64305) is a potent H1-histamine receptor antagonist, used for allergic disorders.",469.66,"90729-43-4",{"v":4,"d":"4.00"},8.52,"<1","N/A","http://selleckchem.com/products/ebastine.html","C32H39NO2","free base","LAS-W 090,RP64305","CC(C)(C)C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)OC(C3=CC=CC=C3)C4=CC=CC=C4",6.582,2,0,10]
["S4654","Netupitant","f4","L4000-24","in 2mM DMSO","Neurokinin Receptor","Neuronal Signaling","Netupitant (CID6451149) is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity.",578.59,"290297-26-6",{"v":2,"d":"2.00"},3.46,"<1","N/A","http://selleckchem.com/products/netupitant.html","C30H32F6N4O","Free Base","CID6451149, CID 6451149, CID-6451149","CN1CCN(CC1)C2=CC(=C(C=N2)N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C4=CC=CC=C4C",7.132,2,0,7]
["S5018","Mebhydrolin napadisylate","g4","L4000-24","in 2mM DMSO","ADC Cytotoxin,Histamine Receptor","Neuronal Signaling","Mebhydrolin Napadisylate (Diazoline, Diazolin, Incidal, Omeril) is classified as an antihistamine drug classes used to treat allergies.",841.05,"6153-33-9",{"v":8,"d":"8.00"},9.51,"N/A","N/A","http://selleckchem.com/products/mebhydrolin-napadisylate.html","C48H48N4O6S2","salt","Diazoline, Diazolin, Incidal, Omeril","CN1CCC2=C(C1)C3=C(C=CC=C3)[N]2CC4=CC=CC=C4.CN5CCC6=C(C5)C7=C(C=CC=C7)[N]6CC8=CC=CC=C8.O[S](=O)(=O)C9=C%10C=CC=C(C%10=CC=C9)[S](O)(=O)=O",9.536,0,0,6]
["S5427","Alloxazine","h4","L4000-24","in 2mM DMSO","Adenosine Receptor","GPCR & G Protein","Alloxazine (Isoalloxazine) is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor.",214.18,"490-59-5",{"v":2,"d":"2.00"},9.34,"N/A","N/A","http://selleckchem.com/products/alloxazine.html","C10H6N4O2","free base","Isoalloxazine","O=C1NC(=O)C2=C(N1)N=C3C=CC=CC3=N2",0.996,4,2,0]
["S5499","Amantadine","a5","L4000-24","in 2mM DMSO","Influenza Virus","Microbiology","Amantadine (1-Adamantanamine, 1-Adamantylamine, 1-Aminoadamantane) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is an M2 inhibitor which blocks the ion channel formed by the M2 protein that spans the viral membrane.",151.25,"768-94-5",{"v":1,"d":"1.00"},6.61,"N/A","N/A","http://selleckchem.com/products/amantadine.html","C10H17N","free base","1-Adamantanamine, 1-Adamantylamine, 1-Aminoadamantane","N[C]12C[CH]3[CH2]C([CH2][CH](C3)C1)C2",1.495,0,1,0]
["S5577","6-Biopterin","b5","L4000-24","in 2mM DMSO","NOS","Immunology & Inflammation","6-Biopterin ( L-Biopterin, L-Erythro-Biopterin) is a natural product that has been considered as a growth factor for some insects.",237.22,"22150-76-1",{"v":1,"d":"1.00"},4.22,"<1","N/A","https://www.selleckchem.com/products/6-biopterin.html","C9H11N5O3","free base","L-Biopterin, L-Erythro-Biopterin","CC(O)C(O)C1=NC2=C(NC(=NC2=O)N)N=C1",-1.131,4,4,2]
["S6001","pomaglumetad (LY404039)","c5","L4000-24","in 2mM DMSO","GluR","Neuronal Signaling","LY404039 is a potent agonist of recombinant human mGlu2/mGlu3 receptors with Ki of 149 nM/92 nM, shows >100-fold selectivity over ionotropic glutamate receptors, glutamate transporters, and other receptors. Phase 3.",235.22,"635318-11-5",{"v":1,"d":"1.00"},4.25,"<1","N/A","http://selleckchem.com/products/LY2140023(LY404039).html","C7H9NO6S","Free Base","N/A","NC1(C[S](=O)(=O)C2C(C12)C(O)=O)C(O)=O",-4.682,4,1,2]
["S6618","JNJ-42153605","d5","L4000-24","in 2mM DMSO","GluR","Neuronal Signaling","JNJ-42153605 is a potent and selective mGlu2 receptor positive allosteric modulator with an EC50 of 17 nM.",400.44,"1254977-87-1",{"v":4,"d":"4.00"},9.99,"<1","N/A","http://www.selleck.cn/products/jnj-42153605.html","C22H23F3N4","Free Base","N/A","FC(F)(F)C1=C(C=C[N]2C(=NN=C12)CC3CC3)N4CCC(CC4)C5=CC=CC=C5",{"v":4.89,"d":"4.890"},2,0,5]
["S6632","Mirogabalin (DS-5565)","e5","L4000-24","in 2mM DMSO","Others","Others","Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand that has been used in trials studying the treatment of Post-herpetic Neuralgia, Pain Associated With Fibromyalgia, and Diabetic peripheral neuropathic pain.",209.28,"1138245-13-2",{"v":2,"d":"2.00"},9.56,{"v":3,"d":"3.00"},14.33,"http://www.selleck.cn/products/mirogabalin-ds-5565.html","C12H19NO2","Free Base","N/A","CCC1=CC2C(C1)CC2(CN)CC(O)=O",-1.352,1,1,4]
["S7400","ISRIB (trans-isomer)","f5","L4000-24","in 2mM DMSO","PERK","Apoptosis","ISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM and does not have global effects on translation, transcription, or mRNA stability in non-stressed cells.",451.34,"1597403-47-8",{"v":4,"d":"4.00"},8.86,"<1","N/A","http://selleckchem.com/products/isrib-trans-isomer.html","C22H24Cl2N2O4","Free Base","N/A","ClC1=CC=C(OCC(=O)NC2CCC(CC2)NC(=O)COC3=CC=C(Cl)C=C3)C=C1",4.055,4,2,8]
["S8012","Otenabant (CP-945598) HCl","g5","L4000-24","in 2mM DMSO","Cannabinoid Receptor","GPCR & G Protein","Otenabant (CP-945598) HCl is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, exhibits 10,000-fold greater selectivity against human CB2 receptor. Phase 1.",546.88,"686347-12-6",{"v":5,"d":"5.00"},9.14,"<1","N/A","http://selleckchem.com/products/cp-945598-hcl.html","C25H25Cl2N7O.HCl","Hydrochloride","Otenabant","Cl.CCNC1(CCN(CC1)C2=NC=NC3=C2N=C([N]3C4=CC=C(Cl)C=C4)C5=CC=CC=C5Cl)C(N)=O",{"v":0,"d":"0.000"},0,0,0]
["S9209","Tritetradecanoin","h5","L4000-24","in 2mM DMSO","Others","Others","Tritetradecanoin, found in Myristica fragrans Houtt., is used as an antiadhesion agent and lubricating agent.",723.16,"555-45-3",{"v":3,"d":"3.00"},4.15,"N/A","N/A","https://www.selleckchem.com/products/tritetradecanoin.html","C45H86O6","free base","N/A","CCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC",16.784,6,0,44]
["S9257","Acetylshikonin","a6","L4000-24","in 2mM DMSO","P450 (e.g. CYP17)","Metabolism","Acetylshikonin is a biologically active compound with anti-cancer and anti-inflammatory activity, which is isolated from the roots of Lithospermum erythrorhizoma. It is a novel general P450 inhibitor with IC50 values of 1.4-4.0 μM for all tested P450s.",330.33,"24502-78-1",{"v":2,"d":"2.00"},6.05,"N/A","N/A","https://www.selleckchem.com/products/acetylshikonin.html","C18H18O6","free base","N/A","CC(C)=CCC(OC(C)=O)C1=CC(=O)C2=C(C(=CC=C2O)O)C1=O",2.824,4,2,5]
["S3304","Stylopine","b6","L4000-24","in 2mM DMSO","COX,Interleukins,NOS,PGES,TNF-alpha","Immunology & Inflammation","Stylopine ((R,S)-Stylopine, Tetrahydrocoptisine) reduces nitric oxide (NO), prostaglandin E2 (PGE2), tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta), and the IL-6 production and cyclooxygenase-2 (COX-2) activity caused by the LPS stimulation. Stylopine is a major component of the leaf of Chelidonium majus L.",323.34,"4312-32-7",{"v":2.5,"d":"2.50"},7.73,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/stylopine-trahydocoptisine-.html","C19H17NO4","free base","(R,S)-Stylopine, Tetrahydrocoptisine","C1OC2=CC3=C(C=C2O1)C4CC5=CC=C6OCOC6=C5CN4CC3",3.201,4,0,0]
["S6345","3-Nitro-L-tyrosine","c6","L4000-24","in 2mM DMSO","Adrenergic Receptor","Endocrinology & Hormones","3-Nitro-L-tyrosine (3-NT, N-Tyr, MNT), synthesized from L-tyrosine by peroxynitrite, is a product of nitric oxide and superoxide. 3-Nitro-L-tyrosine inhibits the hemodynamic responses to angiotensin II, possibly through the inhibition of alpha 1-adrenoceptor-mediated events.",226.19,"621-44-3",{"v":2,"d":"2.00"},8.84,{"v":1,"d":"1.00"},4.42,"http://www.selleckchem.com/products/3-nitro-l-tyrosine.html","C9H10N2O5","free base","3-NT, N-Tyr, MNT","NC(CC1=CC(=C(O)C=C1)[N+]([O-])=O)C(O)=O",-1.953,1,2,4]
["E0100","Sodium ionophore III","d6","L4000-24","in 2mM DMSO","Sodium Channel","Transmembrane Transporters","Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the assay of sodium activity in blood, plasma, serum. etc.",552.79,"81686-22-8",{"v":3,"d":"3.00"},5.43,"<1","N/A","http://www.selleckchem.com/products/sodium-ionophore-iii.html","C34H52N2O4","free base","ETH2120","O=C(COC1=C(OCC(=O)N(C2CCCCC2)C3CCCCC3)C=CC=C1)N(C4CCCCC4)C5CCCCC5",7.761,4,0,10]
["E0382","W-84 Dibromide","e6","L4000-24","in 2mM DMSO","AChR","Neuronal Signaling","W-84 dibromide (HDMPPA) is a potent allosteric modulator of M2-acetylcholine receptors, which retards 3HN-methylscopolamine dissociation.",708.52,"21093-51-6",{"v":3,"d":"3.00"},4.23,{"v":4,"d":"4.00"},5.65,"http://www.selleckchem.com/products/w-84-dibromide.html","C32H44N4O4.2Br","Dibromide","HDMPPA","[Br-].[Br-].C[N+](C)(CCCCCC[N+](C)(C)CCCN1C(=O)C2=C(C=CC=C2)C1=O)CCCN3C(=O)C4=C(C=CC=C4)C3=O",-4.045,4,0,15]
["E0524","Spinosad","f6","L4000-24","in 2mM DMSO","AChR,Anti-infection","Neuronal Signaling","Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete, is a biological neurotoxic insecticide with a broader action spectrum, targeting the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system.",731.96,"168316-95-8",{"v":3,"d":"3.00"},{"v":4.1,"d":"4.10"},"<1","N/A","http://www.selleckchem.com/products/spinosad.html","C41H65NO10","free base","N/A","NA","NA","NA","NA","NA"]
["E0784","MAO-B-IN-2","g6","L4000-24","in 2mM DMSO","BChE,MAO","Neuronal Signaling","MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC50 values of 0.51 and 7.00 μM, respectively.",310.73,"1253978-24-3",{"v":3,"d":"3.00"},9.65,"<1","N/A","http://www.selleckchem.com/products/mao-b-in-2.html","C18H11ClO3","free base","N/A","ClC1=CC=CC=C1/C=C/C(=O)C2=CC3=CC=CC=C3OC2=O",4.386,3,0,3]
["E0831","Pseudocoptisine chloride","h6","L4000-24","in 2mM DMSO","AChR","Neuronal Signaling","Pseudocoptisine chloride (Isocoptisine chloride) is a quaternary alkaloid with benzylisoquinoline skeleton isolated from Corydalis Tuber, inhibits acetylcholinesterase (AChE) activity with an IC50 of 12.8 μM, showing anti-inflammatory and anti-amnestic effects.",355.77,"30044-78-1",{"v":3,"d":"3.00"},8.43,"<1","N/A","http://www.selleckchem.com/products/pseudocoptisine-chloride.html","C19H14NO4.Cl","Chloride","Isocoptisine chloride","[Cl-].C1OC2=C(O1)C=C3C=[N+;v4]4CCC5=CC6=C(OCO6)C=C5C4=CC3=C2",1.089,4,0,0]
["S8274","STO-609","a7","L4000-24","in 2mM DMSO","AMPK,Autophagy,CaMK","Neuronal Signaling","STO-609 is a specific inhibitor of the Ca2+/Calmodulin-dependent protein kinase kinase(CaM-KK) that inhibits the activities of recombinant CaM-KKα and CaM-KKβ isoforms, with Ki values of 80 and 15 ng/ml, respectively, and also inhibits their autophosphorylation activities. STO-609 inhibits AMPKK activity and inhibits autophagy.",314.29,"52029-86-4","N/A",{"v":2,"d":"2.00"},"N/A","N/A","http://selleckchem.com/products/sto-609.html","C19H10N2O3","free base","N/A","OC(=O)C1=CC=C2C3=NC4=C(C=CC=C4)[N]3C(=O)C5=C2C1=CC=C5",3.633,3,0,1]
["S9464","Tranylcypromine Sulfate","b7","L4000-24","in 2mM DMSO","MAO","Metabolism","Tranylcypromine (Parnate) is an irreversible inhibitor of monoamine oxidase (MAO) with a rapid onset of activity.",364.46,"13492-01-8",{"v":2,"d":"2.00"},5.49,"<1","N/A","http://www.selleckchem.com/products/tranylcypromine-sulfate.html","C18H24N2O4S","Sulfate","Parnate","NC1CC1C2=CC=CC=C2.NC3CC3C4=CC=CC=C4.O[S;v6](O)(=O)=O",{"v":1.78,"d":"1.780"},0,2,2]
["S4586","4-Chloro-DL-phenylalanine","c7","L4000-24","in 2mM DMSO","Hydroxylase","Metabolism","4-Chloro-DL-phenylalanine (Fenclonine, PCPA, CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase,  a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). 4-Chloro-DL-phenylalanine acts pharmacologically to deplete endogenous levels of serotonin.",199.63,"7424-00-2","N/A",{"v":2,"d":"2.00"},"N/A","N/A","http://selleckchem.com/products/4-chloro-dl-phenylalanine.html","C9H10ClNO2","Free Base","Fenclonine, PCPA, CP-10188","NC(CC1=CC=C(Cl)C=C1)C(O)=O",-0.941,1,1,3]
["S1911","Disodium Cromoglycate","a2","L4000-25","in 2mM Water","Calcium Channel","Transmembrane Transporters","Disodium Cromoglycate (Gynazole ,FPL 670 (Cromolyn) Disodium,Cromolyn sodium) is an antiallergic drug with IC50 of 39 μg/mL.",512.33,"15826-37-6","<1","N/A",{"v":2,"d":"2.00"},{"v":3.9,"d":"3.90"},"http://selleckchem.com/products/disodium-Cromoglycate.html","C23H14O11.2Na","Disodium Salt","Gynazole ,FPL 670 (Cromolyn) Disodium,Cromolyn sodium","[Na+].[Na+].OC(COC1=C2C(=O)C=C(OC2=CC=C1)C([O-])=O)COC3=CC=CC4=C3C(=O)C=C(O4)C([O-])=O",-1.178,6,1,8]
["S2106","Azasetron HCl","b2","L4000-25","in 2mM Water","5-HT Receptor","Neuronal Signaling","Azasetron HCl (Y-25130) is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.",386.27,"123040-16-4","<1","N/A",{"v":3,"d":"3.00"},7.77,"http://selleckchem.com/products/azasetron-hcl.html","C17H20ClN3O3.HCl","HCl","Y-25130 HCl","Cl.CN1C(=O)COC2=C(C=C(Cl)C=C12)C(=O)NC3CN4CCC3CC4",1.616,3,1,2]
["S4067","Deferiprone","c2","L4000-25","in 2mM Water","Others","Others","Deferiprone (CP20) is a chelating agent with an affinity for ferric ion (iron III)，binds with ferric ions to form neutral 3:1 (deferiprone:iron) complexes that are stable over a wide range of pH values.",139.15,"30652-11-0","<1","N/A",{"v":1,"d":"1.00"},7.19,"http://selleckchem.com/products/deferiprone.html","C7H9NO2","Free Base","CP20","CN1C=CC(=O)C(=C1C)O",-0.139,1,1,0]
["S4694","Alosetron Hydrochloride","d2","L4000-25","in 2mM Water","5-HT Receptor","Neuronal Signaling","Alosetron Hydrochloride (GR 68755C, GR 68755X, Lotronex) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist.",330.81,"122852-69-1","<1","N/A",{"v":1,"d":"1.00"},3.02,"http://selleckchem.com/products/alosetron-hydrochloride.html","C17H18N4O.HCl","hydrochloride","GR 68755C, GR 68755, GR 68755X, Lotronex, GR-68755, GR68755","Cl.C[N]1C2=C(C(=O)N(CC2)CC3=C(C)N=C[NH]3)C4=C1C=CC=C4",2.036,2,1,2]
["S2050","Strontium Ranelate","e2","L4000-25","in 2mM Water","Calcium Channel","Transmembrane Transporters","Strontium Ranelate is a strontium(II) salt of ranelic acid for (-)-desmethoxyverapamil binding to calcium channel with IC50 of 0.5 mM.",513.49,"135459-87-9","<1","N/A",{"v":2,"d":"2.00"},3.89,"http://www.selleckchem.com/products/strontium-ranelate-protelos.html","C12H6N2O8S.2Sr","Free base","N/A","O=C1CN(CC(=O)O[Sr]O1)C2=C(C#N)C3=C(S2)C(=O)O[Sr]OC(=O)C3",0.569,8,0,1]