{"text_format":"3","workbook":"xlsx","n_sheets":2,"sheets":["General Information","Chemical Data-1728 cpds"],"not_rendered":{"images":2,"defined_names":2},"read":"whole","date_system":"1900"}

{"sheet":"General Information","index":0,"n_rows":515,"n_cols":14,"rows_kept":515,"merged":[[0,3,0,13],[1,1,1,13],[2,0,2,13],[3,1,3,13],[4,1,4,2],[4,3,4,13],[5,1,5,2],[5,3,5,13],[6,1,7,2],[6,3,6,13],[7,3,7,13],[8,1,8,2],[8,3,8,13],[9,1,11,2],[9,3,9,13],[10,3,11,13],[14,1,14,13],[16,1,17,1],[16,2,17,2],[16,13,17,13],[18,1,19,1],[18,2,19,2],[18,13,19,13],[20,1,21,1],[20,2,21,2],[20,13,21,13],[22,1,23,1],[22,2,23,2],[22,13,23,13],[24,1,25,1],[24,2,25,2],[24,13,25,13],[26,1,27,1],[26,2,27,2],[26,13,27,13],[28,1,29,1],[28,2,29,2],[28,13,29,13],[30,1,31,1],[30,2,31,2],[30,13,31,13],[35,1,35,13],[37,1,38,1],[37,2,38,2],[37,13,38,13],[39,1,40,1],[39,2,40,2],[39,12,40,12],[39,13,40,13],[41,1,42,1],[41,2,42,2],[41,13,42,13],[43,1,44,1],[43,2,44,2],[43,13,44,13],[45,1,46,1],[45,2,46,2],[45,6,46,6],[45,13,46,13],[47,1,48,1],[47,2,48,2],[47,13,48,13],[49,1,50,1],[49,2,50,2],[49,5,50,5],[49,13,50,13],[51,1,52,1],[51,2,52,2],[51,13,52,13],[56,1,56,13],[58,1,59,1],[58,2,59,2],[58,13,59,13],[60,1,61,1],[60,2,61,2],[60,13,61,13],[62,1,63,1],[62,2,63,2],[62,13,63,13],[64,1,65,1],[64,2,65,2],[64,12,65,12],[64,13,65,13],[66,1,67,1],[66,2,67,2],[66,13,67,13],[68,1,69,1],[68,2,69,2],[68,13,69,13],[70,1,71,1],[70,2,71,2],[70,3,71,3],[70,13,71,13],[72,1,73,1],[72,2,73,2],[72,8,73,8],[72,13,73,13],[77,1,77,13],[79,1,80,1],[79,2,80,2],[79,13,80,13],[81,1,82,1],[81,2,82,2],[81,13,82,13],[83,1,84,1],[83,2,84,2],[83,13,84,13],[85,1,86,1],[85,2,86,2],[85,13,86,13],[87,1,88,1],[87,2,88,2],[87,13,88,13],[89,1,90,1],[89,2,90,2],[89,13,90,13],[91,1,92,1],[91,2,92,2],[91,13,92,13],[93,1,94,1],[93,2,94,2],[93,13,94,13],[98,1,98,13],[100,1,101,1],[100,2,101,2],[100,13,101,13],[102,1,103,1],[102,2,103,2],[102,13,103,13],[104,1,105,1],[104,2,105,2],[104,13,105,13],[106,1,107,1],[106,2,107,2],[106,13,107,13],[108,1,109,1],[108,2,109,2],[108,13,109,13],[110,1,111,1],[110,2,111,2],[110,13,111,13],[112,1,113,1],[112,2,113,2],[112,13,113,13],[114,1,115,1],[114,2,115,2],[114,13,115,13],[119,1,119,13],[121,1,122,1],[121,2,122,2],[121,13,122,13],[123,1,124,1],[123,2,124,2],[123,13,124,13],[125,1,126,1],[125,2,126,2],[125,13,126,13],[127,1,128,1],[127,2,128,2],[127,6,128,6],[127,13,128,13],[129,1,130,1],[129,2,130,2],[129,13,130,13],[131,1,132,1],[131,2,132,2],[131,13,132,13],[133,1,134,1],[133,2,134,2],[133,13,134,13],[135,1,136,1],[135,2,136,2],[135,13,136,13],[140,1,140,13],[142,1,143,1],[142,2,143,2],[142,13,143,13],[144,1,145,1],[144,2,145,2],[144,13,145,13],[146,1,147,1],[146,2,147,2],[146,13,147,13],[148,1,149,1],[148,2,149,2],[148,13,149,13],[150,1,151,1],[150,2,151,2],[150,13,151,13],[152,1,153,1],[152,2,153,2],[152,13,153,13],[154,1,155,1],[154,2,155,2],[154,13,155,13],[156,1,157,1],[156,2,157,2],[156,13,157,13],[161,1,161,13],[163,1,164,1],[163,2,164,2],[163,13,164,13],[165,1,166,1],[165,2,166,2],[165,13,166,13],[167,1,168,1],[167,2,168,2],[167,13,168,13],[169,1,170,1],[169,2,170,2],[169,3,170,3],[169,13,170,13],[171,1,172,1],[171,2,172,2],[171,13,172,13],[173,1,174,1],[173,2,174,2],[173,13,174,13],[175,1,176,1],[175,2,176,2],[175,3,176,3],[175,7,176,7],[175,13,176,13],[177,1,178,1],[177,2,178,2],[177,6,178,6],[177,9,178,9],[177,13,178,13],[182,1,182,13],[184,1,185,1],[184,2,185,2],[184,9,185,9],[184,13,185,13],[186,1,187,1],[186,2,187,2],[186,13,187,13],[188,1,189,1],[188,2,189,2],[188,13,189,13],[190,1,191,1],[190,2,191,2],[190,13,191,13],[192,1,193,1],[192,2,193,2],[192,9,193,9],[192,13,193,13],[194,1,195,1],[194,2,195,2],[194,13,195,13],[196,1,197,1],[196,2,197,2],[196,4,197,4],[196,13,197,13],[198,1,199,1],[198,2,199,2],[198,13,199,13],[203,1,203,13],[205,1,206,1],[205,2,206,2],[205,13,206,13],[207,1,208,1],[207,2,208,2],[207,5,208,5],[207,13,208,13],[209,1,210,1],[209,2,210,2],[209,5,210,5],[209,6,210,6],[209,13,210,13],[211,1,212,1],[211,2,212,2],[211,13,212,13],[213,1,214,1],[213,2,214,2],[213,13,214,13],[215,1,216,1],[215,2,216,2],[215,13,216,13],[217,1,218,1],[217,2,218,2],[217,3,218,3],[217,13,218,13],[219,1,220,1],[219,2,220,2],[219,13,220,13],[224,1,224,13],[226,1,227,1],[226,2,227,2],[226,9,227,9],[226,13,227,13],[228,1,229,1],[228,2,229,2],[228,13,229,13],[230,1,231,1],[230,2,231,2],[230,7,231,7],[230,13,231,13],[232,1,233,1],[232,2,233,2],[232,13,233,13],[234,1,235,1],[234,2,235,2],[234,13,235,13],[236,1,237,1],[236,2,237,2],[236,13,237,13],[238,1,239,1],[238,2,239,2],[238,3,239,3],[238,13,239,13],[240,1,241,1],[240,2,241,2],[240,13,241,13],[245,1,245,13],[247,1,248,1],[247,2,248,2],[247,13,248,13],[249,1,250,1],[249,2,250,2],[249,13,250,13],[251,1,252,1],[251,2,252,2],[251,13,252,13],[253,1,254,1],[253,2,254,2],[253,13,254,13],[255,1,256,1],[255,2,256,2],[255,13,256,13],[257,1,258,1],[257,2,258,2],[257,13,258,13],[259,1,260,1],[259,2,260,2],[259,10,260,10],[259,13,260,13],[261,1,262,1],[261,2,262,2],[261,7,262,7],[261,13,262,13],[266,1,266,13],[268,1,269,1],[268,2,269,2],[268,13,269,13],[270,1,271,1],[270,2,271,2],[270,13,271,13],[272,1,273,1],[272,2,273,2],[272,13,273,13],[274,1,275,1],[274,2,275,2],[274,13,275,13],[276,1,277,1],[276,2,277,2],[276,13,277,13],[278,1,279,1],[278,2,279,2],[278,13,279,13],[280,1,281,1],[280,2,281,2],[280,13,281,13],[282,1,283,1],[282,2,283,2],[282,13,283,13],[287,1,287,13],[289,1,290,1],[289,2,290,2],[289,13,290,13],[291,1,292,1],[291,2,292,2],[291,5,292,5],[291,13,292,13],[293,1,294,1],[293,2,294,2],[293,7,294,7],[293,12,294,12],[293,13,294,13],[295,1,296,1],[295,2,296,2],[295,11,296,11],[295,12,296,12],[295,13,296,13],[297,1,298,1],[297,2,298,2],[297,13,298,13],[299,1,300,1],[299,2,300,2],[299,12,300,12],[299,13,300,13],[301,1,302,1],[301,2,302,2],[301,13,302,13],[303,1,304,1],[303,2,304,2],[303,11,304,11],[303,13,304,13],[308,1,308,13],[310,1,311,1],[310,2,311,2],[310,13,311,13],[312,1,313,1],[312,2,313,2],[312,13,313,13],[314,1,315,1],[314,2,315,2],[314,10,315,10],[314,13,315,13],[316,1,317,1],[316,2,317,2],[316,13,317,13],[318,1,319,1],[318,2,319,2],[318,13,319,13],[320,1,321,1],[320,2,321,2],[320,4,321,4],[320,13,321,13],[322,1,323,1],[322,2,323,2],[322,13,323,13],[324,1,325,1],[324,2,325,2],[324,13,325,13],[329,1,329,13],[331,1,332,1],[331,2,332,2],[331,13,332,13],[333,1,334,1],[333,2,334,2],[333,13,334,13],[335,1,336,1],[335,2,336,2],[335,13,336,13],[337,1,338,1],[337,2,338,2],[337,4,338,4],[337,10,338,10],[337,13,338,13],[339,1,340,1],[339,2,340,2],[339,13,340,13],[341,1,342,1],[341,2,342,2],[341,10,342,10],[341,13,342,13],[343,1,344,1],[343,2,344,2],[343,13,344,13],[345,1,346,1],[345,2,346,2],[345,13,346,13],[350,1,350,13],[352,1,353,1],[352,2,353,2],[352,13,353,13],[354,1,355,1],[354,2,355,2],[354,13,355,13],[356,1,357,1],[356,2,357,2],[356,13,357,13],[358,1,359,1],[358,2,359,2],[358,13,359,13],[360,1,361,1],[360,2,361,2],[360,13,361,13],[362,1,363,1],[362,2,363,2],[362,13,363,13],[364,1,365,1],[364,2,365,2],[364,13,365,13],[366,1,367,1],[366,2,367,2],[366,13,367,13],[371,1,371,13],[373,1,374,1],[373,2,374,2],[373,13,374,13],[375,1,376,1],[375,2,376,2],[375,13,376,13],[377,1,378,1],[377,2,378,2],[377,13,378,13],[379,1,380,1],[379,2,380,2],[379,10,380,10],[379,13,380,13],[381,1,382,1],[381,2,382,2],[381,13,382,13],[383,1,384,1],[383,2,384,2],[383,13,384,13],[385,1,386,1],[385,2,386,2],[385,13,386,13],[387,1,388,1],[387,2,388,2],[387,5,388,5],[387,13,388,13],[392,1,392,13],[394,1,395,1],[394,2,395,2],[394,13,395,13],[396,1,397,1],[396,2,397,2],[396,13,397,13],[398,1,399,1],[398,2,399,2],[398,13,399,13],[400,1,401,1],[400,2,401,2],[400,13,401,13],[402,1,403,1],[402,2,403,2],[402,13,403,13],[404,1,405,1],[404,2,405,2],[404,13,405,13],[406,1,407,1],[406,2,407,2],[406,6,407,6],[406,13,407,13],[408,1,409,1],[408,2,409,2],[408,7,409,7],[408,13,409,13],[413,1,413,13],[415,1,416,1],[415,2,416,2],[415,5,416,5],[415,13,416,13],[417,1,418,1],[417,2,418,2],[417,13,418,13],[419,1,420,1],[419,2,420,2],[419,6,420,6],[419,13,420,13],[421,1,422,1],[421,2,422,2],[421,7,422,7],[421,13,422,13],[423,1,424,1],[423,2,424,2],[423,8,424,8],[423,13,424,13],[425,1,426,1],[425,2,426,2],[425,13,426,13],[427,1,428,1],[427,2,428,2],[427,7,428,7],[427,13,428,13],[429,1,430,1],[429,2,430,2],[429,12,430,12],[429,13,430,13],[434,1,434,13],[436,1,437,1],[436,2,437,2],[436,13,437,13],[438,1,439,1],[438,2,439,2],[438,5,439,5],[438,13,439,13],[440,1,441,1],[440,2,441,2],[440,13,441,13],[442,1,443,1],[442,2,443,2],[442,12,443,12],[442,13,443,13],[444,1,445,1],[444,2,445,2],[444,3,445,3],[444,13,445,13],[446,1,447,1],[446,2,447,2],[446,3,447,3],[446,13,447,13],[448,1,449,1],[448,2,449,2],[448,13,449,13],[450,1,451,1],[450,2,451,2],[450,13,451,13],[455,1,455,13],[457,1,458,1],[457,2,458,2],[457,7,458,7],[457,9,458,9],[457,10,458,10],[457,11,458,11],[457,12,458,12],[457,13,458,13],[459,1,460,1],[459,2,460,2],[459,8,460,8],[459,9,460,9],[459,10,460,10],[459,11,460,11],[459,12,460,12],[459,13,460,13],[461,1,462,1],[461,2,462,2],[461,5,462,5],[461,6,462,6],[461,8,462,8],[461,9,462,9],[461,10,462,10],[461,11,462,11],[461,12,462,12],[461,13,462,13],[463,1,464,1],[463,2,464,2],[463,8,464,8],[463,9,464,9],[463,10,464,10],[463,11,464,11],[463,12,464,12],[463,13,464,13],[465,1,466,1],[465,2,466,2],[465,8,466,8],[465,9,466,9],[465,10,466,10],[465,11,466,11],[465,12,466,12],[465,13,466,13],[467,1,468,1],[467,2,468,2],[467,8,468,8],[467,9,468,9],[467,10,468,10],[467,11,468,11],[467,12,468,12],[467,13,468,13],[469,1,470,1],[469,2,470,2],[469,4,470,4],[469,8,470,8],[469,9,470,9],[469,10,470,10],[469,11,470,11],[469,12,470,12],[469,13,470,13],[471,1,472,1],[471,2,472,2],[471,5,472,5],[471,7,472,7],[471,8,472,8],[471,9,472,9],[471,10,472,10],[471,11,472,11],[471,12,472,12],[471,13,472,13],[476,1,476,13],[478,1,479,1],[478,2,479,2],[478,10,479,10],[478,11,479,11],[478,12,479,12],[478,13,479,13],[480,1,481,1],[480,2,481,2],[480,10,481,10],[480,11,481,11],[480,12,481,12],[480,13,481,13],[482,1,483,1],[482,2,483,2],[482,10,483,10],[482,11,483,11],[482,12,483,12],[482,13,483,13],[484,1,485,1],[484,2,485,2],[484,10,485,10],[484,11,485,11],[484,12,485,12],[484,13,485,13],[486,1,487,1],[486,2,487,2],[486,10,487,10],[486,11,487,11],[486,12,487,12],[486,13,487,13],[488,1,489,1],[488,2,489,2],[488,10,489,10],[488,11,489,11],[488,12,489,12],[488,13,489,13],[490,1,491,1],[490,2,491,2],[490,9,491,9],[490,10,491,10],[490,11,491,11],[490,12,491,12],[490,13,491,13],[492,1,493,1],[492,2,493,2],[492,9,493,9],[492,10,493,10],[492,11,493,11],[492,12,493,12],[492,13,493,13],[497,1,497,13],[499,1,500,1],[499,2,500,2],[499,3,500,3],[499,5,500,5],[499,6,500,6],[499,7,500,7],[499,8,500,8],[499,9,500,9],[499,10,500,10],[499,11,500,11],[499,12,500,12],[499,13,500,13],[501,1,502,1],[501,2,502,2],[501,4,502,4],[501,5,502,5],[501,6,502,6],[501,7,502,7],[501,8,502,8],[501,9,502,9],[501,10,502,10],[501,11,502,11],[501,12,502,12],[501,13,502,13],[503,1,504,1],[503,2,504,2],[503,5,504,5],[503,6,504,6],[503,7,504,7],[503,8,504,8],[503,9,504,9],[503,10,504,10],[503,11,504,11],[503,12,504,12],[503,13,504,13],[505,1,506,1],[505,2,506,2],[505,4,506,4],[505,5,506,5],[505,6,506,6],[505,7,506,7],[505,8,506,8],[505,9,506,9],[505,10,506,10],[505,11,506,11],[505,12,506,12],[505,13,506,13],[507,1,508,1],[507,2,508,2],[507,4,508,4],[507,5,508,5],[507,6,508,6],[507,7,508,7],[507,8,508,8],[507,9,508,9],[507,10,508,10],[507,11,508,11],[507,12,508,12],[507,13,508,13],[509,1,510,1],[509,2,510,2],[509,4,510,4],[509,5,510,5],[509,6,510,6],[509,7,510,7],[509,8,510,8],[509,9,510,9],[509,10,510,10],[509,11,510,11],[509,12,510,12],[509,13,510,13],[511,1,512,1],[511,2,512,2],[511,4,512,4],[511,5,512,5],[511,6,512,6],[511,7,512,7],[511,8,512,8],[511,9,512,9],[511,10,512,10],[511,11,512,11],[511,12,512,12],[511,13,512,13],[513,1,514,1],[513,2,514,2],[513,4,514,4],[513,5,514,5],[513,6,514,6],[513,7,514,7],[513,8,514,8],[513,9,514,9],[513,10,514,10],[513,11,514,11],[513,12,514,12],[513,13,514,13]]}
[{"$nulls":3},"FDA approved Anticancer Drug Library  (96-well)-L8000"]
[null,"For more information on Selleck library service, please contact us via +1-832-582-8158 or library@selleckchem.com"]
[]
[null,"Product Details:"]
[null,"Description",null,"A unique collection of 1728 compounds"]
[null,"Container",null,"96 Well"]
[null,"Stability",null,"12 months | ﹣20°C | in DMSO"]
[{"$nulls":3},"24 months | ﹣80°C | in DMSO"]
[null,"Shipping",null,"Blue ice or Dry ice"]
[null,"Formulation",null,"Solubility ≥10 mM pre-dissolved in 10 mM solution and solubility between 2 mM and 10 mM pre-dissolved in 2 mM solution"]
[{"$nulls":3},"In 10 mM DMSO: Plate Layout L8000-01~20;    In 2 mM DMSO: Plate Layout L8000-23\nIn 10 mM Water: Plate Layout L8000-21~22;    In 2 mM Water: Plate Layout L8000-24"]
[]
[]
[]
[null,"Plate layout: L8000-01"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1005","S1022","S1039","S1064","S1144","S1185","S1197","S1209","S1223","S1238","Empty"]
[{"$nulls":3},"Axitinib (AG 013736)","Ridaforolimus (Deforolimus, MK-8669)","Rapamycin (AY-22989)","Masitinib (AB1010)","Ivacaftor (VX-770)","Ritonavir (ABT-538)","Finasteride","Fluorouracil (5-Fluorouracil, 5-FU)","Epirubicin (IMI 28) HCl","Tamoxifen (ICI 46474)"]
[null,"b","Empty","S1007","S1025","S1040","S1068","S1148","S1188","S1199","S1210","S1225","S1241","Empty"]
[{"$nulls":3},"Roxadustat (FG-4592)","Gefitinib (ZD1839)","Sorafenib (BAY 43-9006) tosylate","Crizotinib (PF-02341066)","Docetaxel (RP56976)","Anastrozole (ZD-1033)","Cladribine (RWJ 26251)","Methotrexate (CL-14377)","Etoposide (VP-16)","Vincristine (NSC-67574) sulfate"]
[null,"c","Empty","S1008","S1026","S1042","S1082","S1150","S1189","S1200","S1212","S1227","S1243","Empty"]
[{"$nulls":3},"Selumetinib (AZD6244)","Imatinib (STI571) Mesylate","Sunitinib (SU11248) malate","Vismodegib (GDC-0449)","Paclitaxel (NSC 125973)","Aprepitant (MK-0869)","Decitabine (NSC 127716)","Bendamustine (SDX105) HCl","Raloxifene HCl","Agomelatine (S20098)"]
[null,"d","Empty","S1010","S1028","S1044","S1085","S1156","S1190","S1202","S1213","S1229","S1245","Empty"]
[{"$nulls":3},"Nintedanib (BIBF 1120)","Lapatinib (GW-572016) Ditosylate","Temsirolimus (CCI-779)","Belinostat (PXD101)","Capecitabine (RO 09-1978)","Bicalutamide (ICI-176334)","Dutasteride","Nelarabine","Fludarabine Phosphate","Latrepirdine 2HCl"]
[null,"e","Empty","S1011","S1029","S1047","S1098","S1162","S1191","S1204","S1214","S1231","S1247","Empty"]
[{"$nulls":3},"Afatinib (BIBW2992)","Lenalidomide (CC-5013)","Vorinostat (SAHA)","Rucaparib (AG-014699) phosphate","Pretomanid (PA-824)","Fulvestrant (ICI-182780)","Melatonin (NSC 113928)","Bleomycin (NSC125066) sulfate","Topotecan (NSC609699) HCl","Leflunomide (HWA486)"]
[null,"f","Empty","S1013","S1030","S1053","S1119","S1164","S1192","S1206","S1218","S1233","S1250","Empty"]
[{"$nulls":3},"Bortezomib (PS-341)","Panobinostat (LBH589)","Entinostat (MS-275)","Cabozantinib (BMS-907351)","Lenvatinib (E7080)","Raltitrexed","Bisoprolol fumarate","Clofarabine","2-Methoxyestradiol (2-MeOE2)","Enzalutamide (MDV3100)"]
[null,"g","Empty","S1014","S1033","S1055","S1120","S1168","S1193","S1207","S1221","S1235","S1251","Empty"]
[{"$nulls":3},"Bosutinib (SKI-606)","Nilotinib (AMN-107)","Enzastaurin (LY317615)","Everolimus (RAD001)","Valproic Acid (NSC 93819) sodium salt","Thalidomide (K17)","Tivozanib (AV-951)","Dacarbazine (NSC-45388)","Letrozole (CGS 20267)","Dienogest"]
[null,"h","Empty","S1021","S1035","S1060","S1137","S1178","S1196","S1208","S1222","S1237","S1255","Empty"]
[{"$nulls":3},"Dasatinib (BMS-354825)","Pazopanib HCl (GW786034 HCl)","Olaparib (AZD2281)","Malotilate","Regorafenib (BAY 73-4506)","Exemestane (FCE 24304)","Doxorubicin (Adriamycin) HCl","Dexrazoxane HCl (ICRF-187)","Temozolomide (CCRG 81045)","Nepafenac"]
[]
[]
[]
[null,"Plate layout: L8000-02"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1257","S1280","S1294","S1322","S1333","S1357","S1378","S1393","S1405","S1432","Empty"]
[{"$nulls":3},"Posaconazole (SCH 56592)","Amisulpride","Cilostazol (OPC-13013)","Dexamethasone (MK-125)","Fluoxetine (Lilly 110140) HCl","Lidocaine","Ruxolitinib (INCB018424)","Pirarubicin (NSC-333054)","Vecuronium Bromide","Sumatriptan Succinate"]
[null,"b","Empty","S1259","S1281","S1299","S1324","S1334","S1358","S1379","S1394","S1407","Empty","Empty"]
[{"$nulls":3},"Ramelteon","Aniracetam","Floxuridine (NSC 27640)","Doxazosin Mesylate","Flupirtine maleate","Loratadine (SCH29851)","Isotretinoin","Pizotifen Malate","Bimatoprost"]
[null,"c","Empty","S1260","S1282","S1300","S1326","S1336","S1359","S1385","S1396","S1408","S1437","Empty"]
[{"$nulls":3},"Cinacalcet (AMG-073) HCl","Artemisinin","Tegafur (FT-207)","Edaravone","Fluvoxamine (DU-23000) maleate","Losartan Potassium (DuP 753)","Mosapride Citrate","Resveratrol (SRT501)","Linezolid (PNU-100766)","Tizanidine HCl"]
[null,"d","Empty","S1261","S1283","S1302","S1328","S1340","S1367","S1386","S1397","S1409","S1438","Empty"]
[{"$nulls":3},"Celecoxib (SC 58635)","Asenapine maleate","Ifosfamide (NSC109724)","Etodolac","Gatifloxacin","Amonafide","Nafamostat mesilate (FUT-175)","Rocuronium Bromide","Alfuzosin HCl","Topiramate"]
[null,"e","Empty","S1267","S1284","S1304","Empty","S1342","S1368","S1387","S1398","S1425","S1439","Empty"]
[{"$nulls":3},"Vemurafenib (PLX4032)","Benazepril HCl","Megestrol Acetate",null,"Genistein (NPI 031L)","Acitretin","Naftopidil DiHCl","Stavudine (d4T)","Ranolazine 2HCl","Tranilast (SB 252218)"]
[null,"f","Empty","S1271","S1287","S1305","S1330","S1344","S1373","S1389","S1401","S1426","S1441","Empty"]
[{"$nulls":3},"Acarbose","Bumetanide","Mercaptopurine (6-MP)","Felbamate","Glimepiride","Daptomycin (LY146032)","Omeprazole","Tenofovir","Repaglinide","Venlafaxine HCl"]
[null,"g","Empty","S1276","S1289","Empty","S1331","S1351","S1376","S1390","S1403","S1430","S1442","Empty"]
[{"$nulls":3},"Adapalene","Carmofur",null,"Fluconazole (UK 49858)","Ivermectin (MK-933)","Gestodene","Ondansetron HCl","Tigecycline (GAR-936)","Rolipram (ZK-62711)","Voriconazole (UK-109496)"]
[null,"h","Empty","S1278","S1291","S1319","S1332","S1354","S1377","S1391","S1404","S1431","S1443","Empty"]
[{"$nulls":3},"Altretamine","Cetirizine DiHCl","Costunolide","Flumazenil (RO 15-1788)","Lansoprazole","Drospirenone","Oxcarbazepine","Trilostane","Sildenafil Citrate","Zileuton (A-64077)"]
[]
[]
[]
[null,"Plate layout: L8000-03"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1444","S1468","S1500","S1547","S1576","S1606","S1625","S1635","S1647","S1665","Empty"]
[{"$nulls":3},"Ziprasidone HCl","Alfacalcidol","Betamethasone","Febuxostat","Sulfasalazine (NSC 667219)","Clotrimazole","Ethinyl Estradiol","Erythromycin","Adenosine","Estrone"]
[null,"b","Empty","S1445","S1483","S1501","S1548","S1578","S1607","S1626","S1638","S1649","S1666","Empty"]
[{"$nulls":3},"Zonisamide","Iloperidone","Mycophenolate mofetil (RS-61443)","Dapagliflozin (BMS-512148)","Candesartan (CV-11974)","Rizatriptan Benzoate","Naproxen Sodium","Ibuprofen (NSC 256857)","Zolmitriptan","Flucytosine"]
[null,"c","Empty","S1453","S1485","S1504","S1549","S1591","S1608","S1627","S1639","S1651","S1667","Empty"]
[{"$nulls":3},"Tipifarnib (R115777)","HMN-214","Dyphylline","Nebivolol hydrochloride (R-65824)","Bestatin (NK421)","Pyridostigmine Bromide","Nitazoxanide (NSC 697855)","Amprenavir (VX-478)","Telbivudine","Trichlormethiazide"]
[null,"d","Empty","S1457","S1488","S1505","S1550","S1593","S1613","S1628","S1640","S1652","Empty","Empty"]
[{"$nulls":3},"Atazanavir (BMS-232632) Sulfate","Naratriptan HCl","Aztreonam","Pimobendan","Apixaban (BMS 562247-01)","Silodosin","Triamcinolone Acetonide","Albendazole (SKF-62979)","Monobenzone"]
[null,"e","Empty","S1458","S1490","S1512","S1565","S1601","S1614","S1629","S1641","S1653","S1679","Empty"]
[{"$nulls":3},"Neflamapimod (VX-745)","Ponatinib (AP24534)","Tadalafil (IC351)","Lumacaftor (VX-809)","Reserpine","Riluzole (PK 26124)","Orlistat (Ro 18-0647)","Chlorothiazide","Tretinoin (NSC 122758)","Flurbiprofen"]
[null,"f","Empty","S1465","S1491","S1514","S1567","S1603","S1618","S1630","S1643","S1654","S1680","Empty"]
[{"$nulls":3},"Moxifloxacin (BAY12-8039) HCl","Fludarabine (NSC 118218)","Cyclosporine","Pomalidomide (CC-4047)","Furosemide (NSC 269420)","Sulfameter","Allopurinol","Ursodiol","Phenylbutazone","Disulfiram (NSC 190940)"]
[null,"g","Empty","Empty","S1497","S1517","S1569","S1604","S1622","S1631","S1644","S1655","S1681","Empty"]
[{"$nulls":4},"Pralatrexate (NSC 754230)","Natamycin","Tazarotene","Olmesartan Medoxomil","Prednisone (NSC-10023)","Allopurinol Sodium","Nitrofural","Ezetimibe (SCH-58235)","Mesalamine (5-ASA)"]
[null,"h","Empty","S1467","S1499","S1526","S1573","S1605","Empty","S1633","S1645","S1658","S1683","Empty"]
[{"$nulls":3},"Doxercalciferol","Cefaclor","Quizartinib (AC220)","Fasudil (HA-1077) HCl","Cefdinir",null,"Zafirlukast (ICI-204219)","Ketoprofen","Dofetilide","Ipratropium Bromide"]
[]
[]
[]
[null,"Plate layout: L8000-04"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1685","S1702","S1718","S1734","S1754","S1770","S1784","S1801","S1828","S1845","Empty"]
[{"$nulls":3},"Sulfanilamide","Didanosine","Adefovir Dipivoxil (GS 0840)","Meloxicam","Oxybutynin","Sulfadiazine","Vidarabine","Ranitidine Hydrochloride","Proparacaine HCl","Cimetidine"]
[null,"b","Empty","S1688","S1705","S1721","S1735","S1756","S1771","S1786","S1805","S1829","S1847","Empty"]
[{"$nulls":3},"Betamethasone Dipropionate","Progesterone (NSC 9704)","Azathioprine","Mesna","Enoxacin","Chlorprothixene","Verteporfin (CL 318952)","Acetylcholine Chloride","Pranlukast","Clemastine (HS-592) fumarate"]
[null,"c","Empty","S1689","S1706","S1723","S1736","S1759","S1774","S1787","S1806","S1830","S1848","Empty"]
[{"$nulls":3},"Meprednisone","Lamivudine (BCH-189)","Indomethacin (NSC-77541)","Methocarbamol","Pitavastatin (NK-104) calcium","Thioguanine (NSC 752)","Teniposide","Acipimox","Oxfendazole","Curcumin"]
[null,"d","Empty","S1690","S1709","S1727","S1738","S1760","S1775","S1790","S1808","S1831","S1849","Empty"]
[{"$nulls":3},"Betamethasone Valerate","Estradiol","Levonorgestrel","Telmisartan","Rifapentine","Thiotepa","Rifaximin","Nifedipine (BAY-a-1040)","Carvedilol","Daidzein"]
[null,"e","Empty","S1692","S1712","S1729","S1739","S1761","S1776","S1792","S1811","S1833","S1854","Empty"]
[{"$nulls":3},"Busulfan (NSC-750)","Deferasirox (ICL-670)","Gemfibrozil","Thiabendazole","Suprofen","Toremifene Citrate (NK 622)","Simvastatin (MK 733)","Amiloride (MK-870) HCl","Butoconazole nitrate","Bifonazole"]
[null,"f","Empty","S1693","S1713","S1730","S1741","S1763","S1777","S1793","S1816","S1835","S1855","Empty"]
[{"$nulls":3},"Carbamazepine","Piroxicam","Indapamide","Rifabutin (LM427)","Quetiapine (ICI-204636) fumarate","Ethionamide","Ramipril","Chlorpheniramine Maleate","Azithromycin (CP-62993)","Pefloxacin Mesylate"]
[null,"g","Empty","S1696","S1714","S1732","S1742","S1764","S1778","S1794","S1820","S1839","S1856","Empty"]
[{"$nulls":3},"Hydrocortisone (NSC 10483)","Gemcitabine (LY-188011)","Mitotane","Nevirapine (NSC 641530)","Rifampin (NSC-113926)","Trifluridine (NSC 75520)","Fenofibrate (NSC-281319)","Clofibrate","Chloroxine","Metoprolol Tartrate"]
[null,"h","Empty","S1701","S1715","S1733","S1747","S1768","S1782","S1799","S1827","S1840","S1858","Empty"]
[{"$nulls":3},"Desonide","Glipizide","Methylprednisolone (NSC-19987)","Nimodipine","Cefditoren Pivoxil","Azacitidine (5-Azacytidine)","Ranolazine","Betaxolol HCl","Lomustine","Dienestrol"]
[]
[]
[]
[null,"Plate layout: L8000-05"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1859","S1894","S1910","S1934","S1965","S1990","S2024","S2042","S2059","S2078","Empty"]
[{"$nulls":3},"Diethylstilbestrol","Valsartan (CGP-48933)","Tioconazole","Nystatin (Fungicidin)","Primidone","Capsaicin(Vanilloid)","Ketotifen Fumarate","Cyproterone Acetate","Terazosin HCl Dihydrate","Famotidine"]
[null,"b","Empty","S1869","S1895","S1913","S1937","S1969","S1992","S2025","S2045","S2061","S2080","Empty"]
[{"$nulls":3},"Dapoxetine HCl","Dipyridamole (NSC 515776)","Tropicamide","Isoniazid","Nefiracetam","Fluticasone propionate","Urapidil HCl","Doxifluridine","Lovastatin (MK-803)","Clevidipine Butyrate"]
[null,"c","Empty","S1878","S1896","S1914","S1941","S1971","S2003","S2028","S2046","S2064","S2082","Empty"]
[{"$nulls":3},"Ganciclovir (BW 759)","Hydroxyurea (NSC-32065)","Pregnenolone","Enalapril Maleate","Nicorandil","Maraviroc (UK-427857)","Diclazuril","Pioglitazone HCl","Balofloxacin","Adiphenine HCl"]
[null,"d","Empty","S1880","S1899","S1915","S1949","S1972","S2006","S2029","S2051","S2065","S2086","Empty"]
[{"$nulls":3},"Roxatidine Acetate HCl","Nicotinamide (NSC 13128)","Sulfamethoxazole","Menadione (NSC 4170)","Tamoxifen (ICI 46474) Citrate","Pyrimethamine","Uridine","Captopril","Lafutidine","Ivabradine HCl"]
[null,"e","Empty","S1883","S1903","S1916","S1950","S1973","S2007","S2032","S2053","S2067","S2087","Empty"]
[{"$nulls":3},"Idoxuridine","Diclofenac Sodium","Sulfisoxazole","Metformin HCl","Cyclocytidine HCl","Sulindac","Rebamipide","Cytidine","Ozagrel HCl","Rivastigmine Tartrate"]
[null,"f","Empty","S1884","S1907","S1917","S1952","S1975","S2015","S2037","S2055","S2069","S2090","Empty"]
[{"$nulls":3},"Sparfloxacin","Metronidazole","Crystal Violet","Methoxsalen","Aripiprazole","Suplatast Tosylate","Candesartan Cilexetil","Gimeracil","Argatroban (MCI-9038)","Dexmedetomidine HCl"]
[null,"g","Empty","S1888","S1908","S1920","S1957","S1978","S2017","S2038","S2057","S2072","S2096","Empty"]
[{"$nulls":3},"Deflazacort","Flutamide","Haloperidol","Sulfamethizole","Methscopolamine","Benidipine HCl","Phentolamine Mesylate","Cyclophosphamide (NSC-26271) Monohydrate","Seratrodast(AA-2414)","Almotriptan Malate"]
[null,"h","Empty","S1890","S1909","S1933","S1959","S1979","S2020","S2040","S2058","S2077","S2098","Empty"]
[{"$nulls":3},"Nizatidine","Fluvastatin (XU-62-320) Sodium","Triamcinolone","Tolfenamic Acid","Amiodarone (NSC 85442) HCl","Formoterol Hemifumarate","Nimesulide","Tolnaftate","Atorvastatin Calcium","Bexarotene (LGD1069)"]
[]
[]
[]
[null,"Plate layout: L8000-06"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S2099","S2113","S2130","S2180","S2246","S2264","S2280","S2296","S2310","S2328","Empty"]
[{"$nulls":3},"Temocapril HCl","Cisatracurium Besylate","Atropine sulfate monohydrate","Ixazomib (MLN2238)","Abiraterone Acetate (CB7630)","Artemether","Chlorogenic Acid","Enoxolone","Honokiol (NSC 293100)","Nalidixic acid"]
[null,"b","Empty","S2101","S2114","S2131","S2181","S2250","S2265","S2283","S2299","S2311","S2329","Empty"]
[{"$nulls":3},"Gabexate Mesylate","Dronedarone HCl","Roflumilast (B9302-107)","Ixazomib Citrate (MLN9708) Analogue","(-)-Epigallocatechin Gallate","Artesunate (WR-256283)","Cinchonine(LA40221)","Formononetin","Hyodeoxycholic acid (HDCA)","Naringin"]
[null,"c","Empty","S2102","S2118","S2151","S2199","S2256","S2266","S2284","S2300","S2314","S2331","Empty"]
[{"$nulls":3},"Rasagiline Mesylate","Ibutilide Fumarate","Sonidegib (NVP-LDE225)","Aliskiren Hemifumarate","4-Methylumbelliferone (4-MU)","Asiatic Acid","Colchicine (NSC 757)","Ferulic Acid","Kaempferol (NSC 407289)","Neohesperidin Dihydrochalcone (Nhdc)"]
[null,"d","Empty","S2103","S2119","S2154","Empty","S2258","S2268","S2286","S2302","S2318","S2332","Empty"]
[{"$nulls":3},"Naltrexone HCl","Probucol","Dabigatran (BIBR-1048) etexilate",null,"Esculin","Baicalein","Cyclosporin A (NSC 290193)","Glycyrrhizin (NSC 167409)","Lappaconitine","Neohesperidin"]
[null,"e","Empty","S2105","S2125","S2167","S2217","S2260","S2269","S2287","S2303","S2320","S2334","Empty"]
[{"$nulls":3},"Pantoprazole","Mestranol","Bazedoxifene (TSE-424) acetate","Irinotecan (CPT-11) HCl Trihydrate","Amygdalin","Baicalin (NSC-661431)","Cytisine","Gossypol Acetate","Luteolin","Oleanolic Acid"]
[null,"f","Empty","S2108","S2126","S2169","S2226","S2261","S2270","S2289","S2304","S2321","S2336","Empty"]
[{"$nulls":3},"Flunixin Meglumin","Naftopidil","Rosuvastatin (ZD4522) calcium","Idelalisib","Andrographolide","Bergenin","Daidzin","Gramine","Magnolol","Orotic acid (6-Carboxyuracil)"]
[null,"g","Empty","S2109","S2127","S2173","S2229","S2262","S2271","S2290","S2308","S2322","S2337","Empty"]
[{"$nulls":3},"Imidapril HCl","S-(+)-Rolipram","Telotristat Etiprate (LX 1606 Hippurate)","Eltrombopag (SB497115) Olamine","Apigenin (LY 080400)","Berberine chloride (NSC 646666)","Dihydroartemisinin (DHA)","Hesperetin","(+)-Matrine","Osthole"]
[null,"h","Empty","S2111","S2128","S2177","S2233","S2263","S2277","S2295","S2309","S2325","S2338","Empty"]
[{"$nulls":3},"Lapatinib (GW-572016)","Bazedoxifene (WAY-140424) HCl","Dichlorphenamide","Esomeprazole sodium","Arbutin","Caffeic Acid","Emodin","Hesperidin","Morin Hydrate","Oxymatrine"]
[]
[]
[]
[null,"Plate layout: L8000-07"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S2341","S2354","S2370","S2386","S2401","S2455","S2471","S2487","S2502","S2515","Empty"]
[{"$nulls":3},"(-)-Parthenolide","Sclareol","Ursolic Acid","Indirubin (NSC 105327)","Sodium Danshensu","Bethanechol chloride","Gallamine Triethiodide","Mycophenolic acid","Quinine HCl Dihydrate","Vardenafil HCl Trihydrate"]
[null,"b","Empty","S2344","S2357","S2375","S2387","S2403","S2456","S2473","S2489","S2503","S2516","Empty"]
[{"$nulls":3},"Piperine","Silibinin (NSC 651520)","Aloin","Lappaconite HBr","Tetrandrine (NSC-77037)","Chlorpromazine HCl","Hexestrol","Nateglinide","Racecadotril","Xylazine HCl"]
[null,"c","Empty","S2346","S2358","S2376","S2388","S2422","S2458","S2475","S2492","S2504","S2517","Empty"]
[{"$nulls":3},"Puerarin","Silymarin","Ammonium Glycyrrhizinate","L-carnitine","Ipriflavone (Osteofix)","Clonidine HCl","Imatinib (STI571)","Novobiocin Sodium (NSC 2382)","Ribavirin (ICN-1229)","Maprotiline HCl"]
[null,"d","Empty","S2347","S2362","S2378","S2389","S2423","S2461","S2480","S2493","S2505","S2519","Empty"]
[{"$nulls":3},"Quercetin Dihydrate","Synephrine","Butylscopolamine Bromide","Naringin Dihydrochalcone","(S)-10-Hydroxycamptothecin","Domperidone","Loperamide HCl","Olanzapine","Rosiglitazone (BRL-49653) maleate","Naphazoline HCl"]
[null,"e","Empty","S2348","S2364","S2379","S2390","S2438","S2466","S2481","S2494","S2508","S2528","Empty"]
[{"$nulls":3},"Rotenone (Barbasco)","Tanshinone I","Dioscin","Polydatin","Synephrine HCl","Estriol","Manidipine","Olopatadine HCl","Scopolamine (LSM-4015) HBr","Ciclopirox"]
[null,"f","Empty","S2349","S2365","S2380","S2391","S2439","S2467","S2484","S2496","S2509","S2529","Empty"]
[{"$nulls":3},"Rutaecarpine","Tanshinone IIA","Diosmetin","Quercetin (NSC 9221)","Guanosine","Famciclovir","Milrinone","Ozagrel","Sotalol HCl","Dopamine HCl"]
[null,"g","Empty","S2350","S2366","S2382","S2396","S2443","S2468","S2485","S2497","S2511","S2533","Empty"]
[{"$nulls":3},"Rutin","Taxifolin (Dihydroquercetin)","Evodiamine","Salidroside","Tolbutamide (HLS 831)","Fenbendazole","Mitoxantrone (NSC-301739) 2HCl","Pancuronium dibromide","Sulfadoxine","Ritodrine HCl"]
[null,"h","Empty","S2351","S2369","S2383","S2397","S2450","S2470","S2486","S2499","S2512","S2535","Empty"]
[{"$nulls":3},"Salicin","Troxerutin","Gastrodin","Palmatine chloride","Equol","Fluocinolone Acetonide","Moroxydine HCl","Phenoxybenzamine HCl","Tenoxicam","Econazole nitrate"]
[]
[]
[]
[null,"Plate layout: L8000-08"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S2536","S2553","S2567","S2585","S2606","S2665","S2789","S2840","S2900","S3012","Empty"]
[{"$nulls":3},"Miconazole","5-Aminolevulinic acid HCl","Medroxyprogesterone acetate (NSC-26386)","Brompheniramine hydrogen maleate","Mifepristone (RU486)","Ciprofibrate","Tofacitinib (CP-690550)","Apalutamide (ARN-509)","Cobicistat (GS-9350)","Pazopanib"]
[null,"b","Empty","S2537","S2554","S2569","S2586","S2607","S2673","S2790","S2851","S2902","S3015","Empty"]
[{"$nulls":3},"Secnidazole","Daphnetin","Phenylephrine (NCI-C55641) HCl","Dimethyl Fumarate","Buflomedil HCl","Trametinib (GSK1120212)","Istradefylline","Baricitinib (INCB028050)","S-Ruxolitinib (INCB018424)","Amoxicillin"]
[null,"c","Empty","S2541","S2555","S2570","S2590","S2610","S2680","S2792","S2853","S2907","S3017","Empty"]
[{"$nulls":3},"Clomipramine HCl","Clarithromycin","Prednisolone Acetate","Pioglitazone (AD-4833)","Lonidamine (AF-1890)","Ibrutinib (PCI-32765)","Torcetrapib","Carfilzomib (PR-171)","Pirfenidone (S-7701)","Aspirin (NSC 27223)"]
[null,"d","Empty","Empty","S2556","S2576","S2593","S2611","S2727","S2797","S2868","S2922","S3018","Empty"]
[{"$nulls":4},"Rosiglitazone (BRL 49653)","Xylometazoline HCl","Tolvaptan","Ethisterone","Dacomitinib (PF-00299804)","Lonafarnib (SCH66336)","Alogliptin (SYR-322) benzoate","Icotinib (BPI-2009H)","Niflumic acid"]
[null,"e","Empty","S2543","S2559","S2577","S2601","S2615","S2736","S2807","S2874","S3001","S3019","Empty"]
[{"$nulls":3},"Ceftiofur HCl","Cortisone acetate","Phenacetin","Gliclazide","Noradrenaline bitartrate monohydrate","Fedratinib (TG101348)","Dabrafenib (GSK2118436)","Camostat Mesilate","Clevudine","Ciclopirox ethanolamine"]
[null,"f","Empty","S2549","S2561","S2579","S2602","S2625","S2741","S2809","S2875","S3002","S3021","Empty"]
[{"$nulls":3},"Trospium chloride","Clomifene citrate","Zidovudine","Acemetacin","Fostamatinib (R788)","Niraparib (MK-4827)","MPEP","Prucalopride","Rivaroxaban (BAY 59-7939)","Rimonabant (SR141716)"]
[null,"g","Empty","Empty","S2564","S2581","S2603","Empty","S2760","S2814","S2883","S3005","S3022","Empty"]
[{"$nulls":4},"Cloxacillin Sodium","Quinapril HCl","Tioxolone",null,"Canagliflozin (JNJ 28431754)","Alpelisib (BYL719)","4-Aminohippuric Acid","Paroxetine HCl","Cabazitaxel (XRP6258)"]
[null,"h","Empty","S2552","S2566","S2584","Empty","S2664","S2762","Empty","S2884","S3008","S3023","Empty"]
[{"$nulls":3},"Azelastine HCl","Isoprenaline (NCI-C55630) HCl","Clobetasol propionate",null,"Clinofibrate","Alectinib (CH5424802)",null,"Acesulfame Potassium","Zaltoprofen","Bufexamac"]
[]
[]
[]
[null,"Plate layout: L8000-09"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S3024","S3046","S3079","S3117","S3149","S3175","Empty","S3609","S3627","S3655","Empty"]
[{"$nulls":3},"Lamotrigine","Azilsartan","Atovaquone","Oxybutynin hydrochloride","Estradiol valerate","Atomoxetine HCl",null,"Berbamine dihydrochloride","Tryptamine","Cefepime Dihydrochloride Monohydrate"]
[null,"b","Empty","S3027","S3047","S3080","S3120","S3151","S3176","S3195","S3611","S3635","S3656","Empty"]
[{"$nulls":3},"Fenoprofen calcium hydrate","Otilonium Bromide","Etravirine (TMC125)","Doxepin HCl","Gliquidone","Betahistine 2HCl","Azlocillin sodium salt","(+)-Fangchinoline","Medroxyprogesterone","Piribedil"]
[null,"c","Empty","S3030","S3052","S3081","S3124","S3160","S3178","S3200","S3612","S3639","S3657","Empty"]
[{"$nulls":3},"Niclosamide (BAY2353)","Rupatadine Fumarate","Ulipristal Acetate (CDB 2914)","Dexamethasone Acetate","Ethynodiol diacetate","Brinzolamide","Triflusal","Rosmarinic acid","Tacrine hydrochloride hydrate","Promestriene"]
[null,"d","Empty","S3035","S3054","S3083","S3129","S3162","S3180","S3201","S3615","S3641","S3659","Empty"]
[{"$nulls":3},"Daunorubicin (RP 13057) HCl","Alverine Citrate","Indacaterol Maleate","Trimethoprim","Tylosin tartrate","Eletriptan HBr","Trifluoperazine 2HCl","Dehydrocostus Lactone","Osalmid","Fludrocortisone acetate"]
[null,"e","Empty","S3036","S3057","S3100","S3132","S3167","S3181","Empty","S3616","S3643","S3666","Empty"]
[{"$nulls":3},"Pravastatin sodium","Azilsartan Medoxomil","2-Thiouracil","Sulfamerazine","Altrenogest","Flumequine",null,"Asiaticoside","Amitraz","Ilaprazole"]
[null,"f","Empty","S3037","S3067","S3104","S3137","S3170","S3183","S3212","S3621","S3647","S3668","Empty"]
[{"$nulls":3},"Bepotastine Besilate","Chlorhexidine 2HCl","Moguisteine","Sodium salicylate","Ampicillin sodium","Amitriptyline HCl","Moclobemide (Ro 111163)","Pazufloxacin mesylate","Mafenide Acetate","Thymopentin"]
[null,"g","Empty","S3038","Empty","S3105","S3138","S3172","S3185","S3604","S3622","S3648","S3669","Empty"]
[{"$nulls":3},"Fosaprepitant dimeglumine salt",null,"Nadifloxacin","Methylthiouracil","Anagrelide HCl","Adrenalone HCl","Triptolide (PG490)","Diammonium Glycyrrhizinate","Amlexanox (AA-673)","Carmustine"]
[null,"h","Empty","S3043","S3078","S3116","S3144","S3173","S3186","S3606","S3625","S3654","S3671","Empty"]
[{"$nulls":3},"Rofecoxib","Beclomethasone dipropionate","Sulfathiazole","Darifenacin HBr","Antipyrine","Azatadine dimaleate","Fangchinoline","Tyramine","Tauroursodeoxycholic Acid (TUDCA)","Quinestrol"]
[]
[]
[]
[null,"Plate layout: L8000-10"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S3672","S3690","S3714","S3745","S3774","S3807","S3847","S3883","S3899","S3926","Empty"]
[{"$nulls":3},"Cefonicid sodium","Pargyline hydrochloride","Lifitegrast","Balsalazide disodium","Dehydroandrographolide Succinate Potasium Salt","Dehydroandrographolide","Panaxatriol","Protopine","Hederagenin","Forsythin"]
[null,"b","Empty","S3675","S3692","Empty","S3751","S3776","S3809","S3849","S3885","S3901","S3927","Empty"]
[{"$nulls":3},"Umbelliferone","N-Ethylmaleimide (NEM)",null,"Quinidine hemisulfate hydrate","Sophoricoside","Imperatorin","D-Galactose","Pyrogallol","Astragaloside IV","Swertiamarin"]
[null,"c","Empty","S3676","S3694","Empty","Empty","S3779","S3810","S3850","S3887","S3909","S3930","Empty"]
[{"$nulls":3},"Carbendazim","Glucosamine hydrochloride",null,null,"cis-Anethole","Scutellarin","Glucosamine sulfate","α-L-Rhamnose monohydrate","Catalpol","Liquiritin"]
[null,"d","Empty","S3677","S3697","S3724","S3758","S3785","S3811","S3851","S3889","S3914","S3935","Empty"]
[{"$nulls":3},"Cinnamic acid","Mafenide hydrochloride","Velpatasvir","Sinomenine hydrochloride","Notoginsenoside R1","Ginsenoside Re","Camphor","Arteether","α-Hederin","Nonivamide"]
[null,"e","Empty","S3681","S3698","S3731","S3759","S3788","S3817","S3856","S3892","S3921","S3944","Empty"]
[{"$nulls":3},"Vitamin E Acetate","Nortriptyline hydrochloride","Tipiracil hydrochloride","Norcantharidin","Carvacrol","Harmine hydrochloride","Allantoin","Isopsoralen","Lathyrol","Valproic acid (VPA)"]
[null,"f","Empty","S3684","S3701","S3732","S3763","S3794","S3835","S3868","S3893","S3923","S3945","Empty"]
[{"$nulls":3},"Methacholine chloride","Benactyzine hydrochloride","Avibactam sodium","Cinnamaldehyde","Palmitic acid","Loganin","Harmine","Bornyl acetate","Ginsenoside Rg1","L-Cycloserine"]
[null,"g","Empty","Empty","S3707","S3739","S3766","S3802","S3842","S3870","S3895","S3924","S3951","Empty"]
[{"$nulls":4},"Ethopabate","Calcipotriene","Tanshinone IIA sulfonate sodium","Trigonelline Hydrochloride","Isoquercitrin","D-Pinitol","Sophoridine","Ginsenoside Rb1","Tannic acid"]
[null,"h","Empty","S3687","S3711","S3742","S3769","S3805","S3846","S3876","S3898","S3925","S3956","Empty"]
[{"$nulls":3},"Urea","Carbasalate Calcium","Cholic acid","Palmatine","Stevioside","Eupatilin","Indigo","Hydroxy Camptothecine","(-)-Epicatechin gallate","Tetramethylpyrazine"]
[]
[]
[]
[null,"Plate layout: L8000-11"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S3957","S3975","S4001","S4014","S4026","S4045","Empty","S4078","S4089","S4110","Empty"]
[{"$nulls":3},"Gamma-Oryzanol","Protocatechuic acid","Cabozantinib malate","Hyoscyamine","Hydroxyzine 2HCl","Pheniramine Maleate",null,"Mefenamic Acid","Halobetasol Propionate","Estradiol Benzoate"]
[null,"b","Empty","S3959","S3980","S4003","S4017","S4034","S4046","S4065","S4079","S4090","S4113","Empty"]
[{"$nulls":3},"(+)-Borneol","Pyridoxine","Lithocholic acid","Allylthiourea","Diphemanil Methylsulfate","Estradiol Cypionate","Guanabenz Acetate","Ticagrelor","Fenspiride HCl","Desvenlafaxine"]
[null,"c","Empty","S3966","S3982","S4004","S4018","Empty","S4047","S4070","S4080","S4095","S4114","Empty"]
[{"$nulls":3},"Nifuratel","Batyl alcohol","Ethambutol 2HCl","Sennoside B",null,"Bisacodyl","Guanidine HCl","Triamterene","Difluprednate","Triclabendazole"]
[null,"d","Empty","S3967","S3983","S4007","S4019","S4037","S4049","S4071","S4081","S4098","S4118","Empty"]
[{"$nulls":3},"Flavone","Caryophyllene oxide","Pentamidine isethionate","Avanafil","Doxapram HCl","Valdecoxib","Griseofulvin","Sulfacetamide Sodium","Halcinonide","Histamine 2HCl"]
[null,"e","Empty","S3968","S3984","S4009","S4022","S4039","S4051","S4072","S4082","S4101","S4119","Empty"]
[{"$nulls":3},"Histamine","Nordihydroguaiaretic acid (NDGA)","Mirabegron","Probenecid","Methazolamide","Nabumetone","Decamethonium Bromide","Spiramycin","Voglibose","Pefloxacin Mesylate Dihydrate"]
[null,"f","Empty","S3970","S3987","S4010","S4023","S4040","S4053","S4073","S4083","S4102","S4120","Empty"]
[{"$nulls":3},"Vindoline","L-Tryptophan","Acebutolol HCl","Procaine HCl","Norethindrone","Sertraline HCl","Sodium 4-Aminosalicylate","Vitamin A Acetate","Eprosartan Mesylate","Sulconazole Nitrate"]
[null,"g","Empty","Empty","S3996","S4011","S4024","S4041","S4054","S4075","S4086","S4104","S4123","Empty"]
[{"$nulls":4},"Thioctic acid","Ampiroxicam","Homatropine Methylbromide","Olsalazine Sodium","Spironolactone","Zinc Pyrithione","Loxapine Succinate","Diminazene Aceturate","Timolol Maleate"]
[null,"h","Empty","S3974","S3998","S4012","S4025","S4042","S4059","S4076","S4088","S4107","S4124","Empty"]
[{"$nulls":3},"(+)-Catechin hydrate","(+)-α-Lipoic acid","Desloratadine","Homatropine Bromide","Nafcillin Sodium","Sodium Nitroprusside Dihydrate","Propranolol HCl","Flumethasone","Clofazimine","Tolazoline HCl"]
[]
[]
[]
[null,"Plate layout: L8000-12"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4125","S4155","S4169","S4184","S4196","S4213","S4227","S4243","S4255","S4267","Empty"]
[{"$nulls":3},"Sodium Phenylbutyrate","Chlorzoxazone","Teriflunomide","Penciclovir","Ethacridine lactate monohydrate","Dirithromycin","Fidaxomicin","Deoxycorticosterone acetate","Quinacrine 2HCl","Diacerein"]
[null,"b","Empty","S4131","S4159","S4170","S4185","S4197","S4214","S4230","S4244","S4256","S4268","Empty"]
[{"$nulls":3},"Levodropropizine","Bezafibrate","Coumarin","Tiratricol","Bemegride","Sucralose","Oxaprozin","Serotonin HCl","Buspirone HCl","Flufenamic acid"]
[null,"c","Empty","S4135","S4160","S4171","S4186","S4201","S4216","S4231","S4246","S4257","S4269","Empty"]
[{"$nulls":3},"Clorprenaline HCl","Penicillin G Sodium","Choline Chloride","Domiphen Bromide","Florfenicol","Valnemulin HCl","Pilocarpine HCl","Tranylcypromine (2-PCPA) HCl","Alizapride HCl","Vinorelbine ditartrate (KW-2307)"]
[null,"d","Empty","S4136","S4162","S4172","S4187","S4206","S4217","S4237","S4247","S4259","S4270","Empty"]
[{"$nulls":3},"Carprofen","Benzethonium Chloride","Cetylpyridinium Chloride","Salicylanilide","Cysteamine HCl","Liothyronine Sodium","Primaquine Diphosphate","Prucalopride Succinate","Vilazodone HCl","Oxiracetam"]
[null,"e","Empty","S4147","S4164","S4175","S4188","S4207","S4221","S4238","S4249","S4260","S4277","Empty"]
[{"$nulls":3},"Azithromycin Dihydrate","Doxofylline","Sulfaguanidine","Sasapyrine","Clofibric Acid","Benzbromarone","Cepharanthine","Flopropione","Tamibarotene","Bambuterol HCl"]
[null,"f","Empty","S4149","S4165","S4177","S4190","S4208","S4223","S4239","S4250","S4263","S4278","Empty"]
[{"$nulls":3},"Amfenac Sodium Monohydrate","Benzydamine HCl","Uracil","Cinchophen","Chromocarb","Mevastatin","Bergapten","Sulfamethoxypyridazine","Efaproxiral Sodium","Carteolol HCl"]
[null,"g","Empty","S4151","S4166","S4181","S4192","S4210","S4224","S4240","Empty","S4265","S4280","Empty"]
[{"$nulls":3},"Penfluridol","Chlorpropamide","Nicardipine HCl","Chlorquinaldol","Benzocaine","Erythritol","Doxylamine Succinate",null,"Nicaraven","Meclofenoxate (Centrophenoxine) HCl"]
[null,"h","Empty","S4152","S4167","S4182","S4195","Empty","S4225","S4242","S4253","S4266","S4282","Empty"]
[{"$nulls":3},"Ethamsylate","Cyromazine","Nifuroxazide","Broxyquinoline",null,"Mexiletine HCl","Cetrimonium Bromide (CTAB)","Epinastine HCl","Brimonidine Tartrate","Nelfinavir (AG 1343) Mesylate"]
[]
[]
[]
[null,"Plate layout: L8000-13"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4283","S4297","S4330","S4353","S4381","S4502","S4516","S4535","S4550","S4578","Empty"]
[{"$nulls":3},"Cyclobenzaprine HCl","Mupirocin","Isoetharine Mesylate","Terfenadine","Proadifen HCl","Eltrombopag","(+)-Camphor","Methylene Blue","Azelaic acid","Tyloxapol"]
[null,"b","Empty","S4285","S4299","S4334","S4354","S4382","S4504","S4517","S4538","S4552","S4583","Empty"]
[{"$nulls":3},"Ospemifene","Dicoumarol","Mesoridazine Besylate","Thiostrepton","Pyrilamine Maleate","6-Mercaptopurine (6-MP) Monohydrate","Cefotaxime sodium","Pantoprazole sodium","Bithionol","Butamben"]
[null,"c","Empty","S4288","S4303","S4335","S4358","S4387","S4505","S4521","S4539","S4561","S4585","Empty"]
[{"$nulls":3},"Chloroambucil","9-Aminoacridine","Metaproterenol Sulfate","Pimozide","Bendroflumethiazide","Vinblastine (NSC-49842) sulfate","DEET","Salicylic acid","Danthron","Succinylsulfathiazole"]
[null,"d","Empty","S4289","S4307","S4336","S4361","S4394","S4506","S4524","S4541","S4564","S4587","Empty"]
[{"$nulls":3},"Metoclopramide HCl","Auranofin","Metaraminol Bitartrate","Cinoxacin","Clofoctol","Acetazolamide","2-Ethoxybenzamide","Triclosan","Diethylcarbamazine citrate","Pentylenetetrazol"]
[null,"e","Empty","S4291","S4308","S4338","S4362","S4396","S4507","S4526","S4544","S4569","S4589","Empty"]
[{"$nulls":3},"Labetalol HCl","Benzthiazide","Methoxamine HCl","Glafenine HCl","Digoxigenin","17-Hydroxyprogesterone","Fenbufen","Urethane","Fluphenazine dihydrochloride","Amodiaquine dihydrochloride dihydrate"]
[null,"f","Empty","S4292","S4309","S4339","S4367","S4404","S4509","S4527","S4546","S4570","S4591","Empty"]
[{"$nulls":3},"Diphenidol HCl","Bromocriptine Mesylate","Meticrane","Suxibuzone","Pasiniazid","4-Aminoantipyrine","Fenofibric acid","Xylitol","Halothane","Nitroxoline"]
[null,"g","Empty","S4294","S4316","S4344","S4373","S4406","S4512","S4528","S4547","S4571","S4593","Empty"]
[{"$nulls":3},"Procainamide HCl","Clopamide","Oxprenolol HCl","Dicyclomine HCl","Pindolol","Aceglutamide","Furazolidone","8-Hydroxyquinoline","Hexylresorcinol","Chlormadinone acetate"]
[null,"h","Empty","S4295","S4317","S4345","S4375","S4416","S4514","S4534","S4548","S4576","S4594","Empty"]
[{"$nulls":3},"Meclofenamate Sodium","Clorgyline HCl","Pentoxifylline","Mepenzolate Bromide","Trimipramine Maleate","Acetylleucine","6-Acetamidohexanoic acid","Aminoguanidine hydrochloride","Sulfabenzamide","Cephalothin sodium"]
[]
[]
[]
[null,"Plate layout: L8000-14"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4595","S4609","S4635","S4658","S4673","S4693","S4711","S4731","S4751","S4779","Empty"]
[{"$nulls":3},"Cefazolin Sodium","Diflunisal","Cyproheptadine hydrochloride sesquihydrate","Hydroquinidine","Etonogestrel","Guanfacine Hydrochloride","Esculetin","Perphenazine","Cisapride hydrate","Menadiol Diacetate"]
[null,"b","Empty","S4596","S4610","Empty","S4660","S4679","S4695","S4714","S4735","S4753","S4783","Empty"]
[{"$nulls":3},"Cefixime","Mebendazole",null,"Glycopyrrolate","Terazosin HCl","D panthenol","(-)-Menthol","Salvianolic acid B","Ganoderic acid A","Benzyl isothiocyanate"]
[null,"c","Empty","S4599","S4619","S4641","S4662","Empty","S4696","S4717","S4736","S4754","Empty","Empty"]
[{"$nulls":3},"Benzyl benzoate","Itopride hydrochloride","Tedizolid Phosphate","Atazanavir",null,"CarbinoxaMine Maleate","Isatin","Trapidil","Betulin"]
[null,"d","Empty","S4600","S4625","S4646","S4665","S4682","S4697","S4718","S4737","Empty","Empty","Empty"]
[{"$nulls":3},"Benzyl alcohol","Alcaftadine","Ciclesonide","Rabeprazole sodium","Loxoprofen","Saxagliptin hydrate","Acetylcholine iodide","Psoralen"]
[null,"e","Empty","S4601","S4628","S4647","S4666","S4685","S4701","S4722","S4744","S4759","S4797","Empty"]
[{"$nulls":3},"Clioquinol","(+/-)-Sulfinpyrazone","Cefmenoxime hydrochloride","Sivelestat sodium tetrahydrate","Efavirenz","2-Deoxy-D-glucose (2-DG)","(+)-Catechin","Anethole trithione","p-Coumaric Acid","Nicergoline"]
[null,"f","Empty","S4602","S4629","S4650","S4667","S4686","S4706","S4723","S4748","S4769","Empty","Empty"]
[{"$nulls":3},"Acetohydroxamic acid","Chlorotrianisene","Atipamezole","Lidocaine hydrochloride","Vitamin E","Eugenol","(-)Epicatechin","Ondansetron Hydrochloride Dihydrate","L-5-Hydroxytryptophan"]
[null,"g","Empty","S4603","S4630","S4651","S4669","S4687","S4707","S4725","S4749","S4772","S4817","Empty"]
[{"$nulls":3},"Gallic acid","Diazoxide","Etoricoxib","Benzocaine hydrochloride","Rivastigmine","Oleic Acid","Benzenesulfonamide","Citalopram HBr","alpha-Asarone","Atenolol"]
[null,"h","Empty","S4604","S4633","S4656","S4672","S4690","S4709","S4727","S4750","Empty","S4832","Empty"]
[{"$nulls":3},"Levofloxacin hydrate","Isosorbide Mononitrate","Parecoxib","Dimenhydrinate","Escin","Latanoprost","Cinnarizine","Sulfacetamide sodium salt hydrate",null,"Tolmetin"]
[]
[]
[]
[null,"Plate layout: L8000-15"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4833","S4856","S4940","S4977","S5009","S5032","S5062","S5091","S5163","S5234","Empty"]
[{"$nulls":3},"Cefoxitin sodium","Iproniazid","Maltol","Efonidipine","Brivudine","Mephenesin","Daclatasvir Dihydrochloride","Geranyl acetate","7-Methoxycoumarin","Nintedanib Ethanesulfonate Salt"]
[null,"b","Empty","S4834","S4862","S4941","S4980","S5012","S5033","S5067","S5113","S5177","S5240","Empty"]
[{"$nulls":3},"Propantheline bromide","Squalene","Farnesol","Anamorelin","Octenidine Dihydrochloride","Terconazole","Losartan","Propyl gallate","Naproxen","Lenvatinib (E7080) Mesylate"]
[null,"c","Empty","S4835","S4867","S4952","S4988","S5014","S5040","S5069","Empty","S5200","S5241","Empty"]
[{"$nulls":3},"Aceclofenac","Propacetamol hydrochloride","Fumaric acid","Tiamulin fumarate","Crisaborole (AN2728)","Tiamulin","Dabrafenib Mesylate",null,"Diaveridine","Lapatinib ditosylate monohydrate"]
[null,"d","Empty","S4836","S4878","S4953","S5001","S5016","S5049","S5074","S5130","S5205","S5243","Empty"]
[{"$nulls":3},"Nilutamide","Neticonazole Hydrochloride","Usnic acid","Tofacitinib (CP-690550) Citrate","Isoprinosine","Thiocolchicoside","Argatroban Monohydrate","Taurocholic acid sodium salt hydrate","Nilotinib hydrochloride","Ruxolitinib Phosphate"]
[null,"e","Empty","S4837","S4885","S4957","S5002","S5020","S5052","S5077","S5138","S5209","S5247","Empty"]
[{"$nulls":3},"Ibudilast","Taurolidine","Linalool","Fingolimod (FTY720) HCl","Tilorone dihydrochloride","Granisetron","Regorafenib (BAY-734506) Monohydrate","Citral","Enoxacin Sesquihydrate","Selamectin"]
[null,"f","Empty","S4838","Empty","S4958","S5003","S5023","S5058","S5078","S5141","S5210","S5253","Empty"]
[{"$nulls":3},"Acotiamide hydrochloride",null,"Glycocholic acid","Tacrolimus (FK506)","Nadolol","Revaprazan Hydrochloride","Osimertinib mesylate","Pyrithioxin","Sulfamethazine Sodium Salt","Cisapride (R 51619)"]
[null,"g","Empty","S4849","S4896","S4975","S5006","S5027","S5059","S5082","S5145","S5211","S5254","Empty"]
[{"$nulls":3},"Levocetirizine Dihydrochloride","Elagolix Sodium","Fimasartan","Teprenone","Mebeverine Hydrochloride","Pixantrone Maleate","Vitamin K2","Protoporphyrin IX","4-Aminosalicylic acid","Dasatinib hydrochloride"]
[null,"h","Empty","S4852","S4932","S4976","S5007","S5029","S5060","S5083","S5159","S5233","S5256","Empty"]
[{"$nulls":3},"Gadopentetate Dimeglumine","Proxyphylline","Sulfalene (SMPZ)","Delamanid","Etofylline","Metadoxine","Lentinan","Doxycycline","Fenretinide (NSC 374551)","Benproperine phosphate"]
[]
[]
[]
[null,"Plate layout: L8000-16"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S5273","S5297","S5353","S5392","S5424","S5458","S5486","S5498","S5537","S5563","Empty"]
[{"$nulls":3},"Canrenone","Vidarabine monohydrate","Cefpiramide sodium","Mepivacaine","Carbaryl","Verbascoside","Fluorometholone","Betahistine mesylate","Tizanidine","Thioridazine hydrochloride"]
[null,"b","Empty","S5278","S5298","S5358","S5398","S5428","S5459","S5487","S5502","S5538","S5564","Empty"]
[{"$nulls":3},"Tedizolid (TR-700)","Amoxicillin trihydrate","Regadenoson","Nefazodone hydrochloride","Promazine hydrochloride","Aucubin","Cefoperazone sodium","Ilaprazole sodium","Tropisetron","Xylazine"]
[null,"c","Empty","S5279","S5301","S5365","S5399","S5435","S5466","S5488","S5504","S5544","S5566","Empty"]
[{"$nulls":3},"Fendiline hydrochloride","Carglumic Acid","Alogliptin","Chlorprothixene hydrochloride","Quinacrine Dihydrochloride Dihydrate","Saikosaponin A","Fluorescein","Ropivacaine","D-Ribose","Dapagliflozin propanediol monohydrate"]
[null,"d","Empty","S5281","Empty","S5366","S5401","S5447","S5476","S5490","Empty","S5550","S5573","Empty"]
[{"$nulls":3},"Dapiprazole Hydrochloride",null,"Fipronil","Tegaserod Maleate","Triprolidine Hydrochloride","Rolapitant","Disopyramide",null,"Ethyl gallate","Tilmicosin phosphate"]
[null,"e","Empty","S5284","S5325","S5369","S5407","S5452","S5479","S5491","S5507","S5552","S5582","Empty"]
[{"$nulls":3},"Adenosine 5'-monophosphate monohydrate","Nitisinone","Ethoxyquin","Squalane","Sanguinarine chloride","Cloperastine hydrochloride","Lomefloxacin","Trimebutine maleate","Amenamevir","Cytarabine hydrochloride"]
[null,"f","Empty","S5286","S5327","S5371","S5416","S5453","S5480","S5492","Empty","S5554","S5592","Empty"]
[{"$nulls":3},"Ramatroban","Meisoindigo","Ajmaline","Metyrapone","Hyperoside","Clidinium Bromide","Econazole",null,"Lanatoside C","Vitamin A"]
[null,"g","Empty","S5288","S5341","S5372","S5418","S5454","S5481","S5493","S5527","S5556","S5623","Empty"]
[{"$nulls":3},"Estropipate","Metroprolol succinate","Methyl Aminolevulinate Hydrochloride","Parecoxib Sodium","Saikosaponin D","Molindone hydrochloride","Atropine sulfate","Salmeterol","(-)-Sparteine Sulfate","Bedaquiline"]
[null,"h","Empty","S5293","S5345","S5377","S5419","S5457","S5485","S5494","S5535","S5561","S5625","Empty"]
[{"$nulls":3},"Nimustine Hydrochloride","(+/-)-nerolidol","Dibutyl phthalate","1,4-Cineole","Curculigoside","Desipramine Hydrochloride","Salbutamol","Moxifloxacin","Ethacrynic Acid","Ammonium lactate"]
[]
[]
[]
[null,"Plate layout: L8000-17"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S5627","S5662","S5683","S5715","S5737","S5781","S5863","S5950","S6136","S6411","Empty"]
[{"$nulls":3},"Amsacrine hydrochloride","Ranitidine","Isoproterenol sulfate dihydrate","Atorvastatin","Diclofenac Epolamine","Raloxifene","Metronidazole Benzoate","Fingolimod","(±)-α-Bisabolol","Nimorazole"]
[null,"b","Empty","S5649","S5663","S5698","S5716","S5740","S5787","S5868","S6003","S6288","S6441","Empty"]
[{"$nulls":3},"Hydroxyzine pamoate","Minaprine dihydrochloride","Ketorolac tromethamine salt","Abemaciclib (LY2835219)","Palonosetron","Dronedarone","DL-Menthol","Ataluren (PTC124)","Chlorhexidine diacetate","Riboflavin Tetrabutyrate"]
[null,"c","Empty","S5651","S5664","S5703","S5717","S5749","S5795","S5871","S6055","S6400","S6453","Empty"]
[{"$nulls":3},"Dexrazoxane","Orphenadrine Hydrochloride","Carvedilol Phosphate","Acetohexamide","Chlorpromazine","Rasagiline","Trans-Tranilast","(S)-(−)-Limonene","Glucosamine","Bicyclol"]
[null,"d","Empty","S5654","S5665","S5705","S5727","S5754","S5802","S5872","S6058","S6402","S6455","Empty"]
[{"$nulls":3},"Indacaterol","Drofenine Hydrochloride","Raceanisodamine","Tetryzoline","Baricitinib phosphate","Alprenolol hydrochloride","Estradiol dipropionate","β-Caryophyllene","2-Aminoethanethiol","Clebopride malate"]
[null,"e","Empty","S5656","S5666","S5709","S5728","S5761","S5808","S5873","S6068","S6404","S6456","Empty"]
[{"$nulls":3},"Diphenylpyraline hydrochloride","Moxisylyte hydrochloride","Norgestrel","Delapril Hydrochloride","Citric acid","Relugolix","Scopolamine HBr trihydrate","Doxycycline monohydrate","Salicylamide","Glycyrrhetinic acid"]
[null,"f","Empty","S5657","S5667","S5710","S5729","S5763","S5812","S5901","S6073","S6407","S6457","Empty"]
[{"$nulls":3},"Ertapenem sodium","Fruquintinib (HMPL-013)","Ambroxol","Fosfosal","D-Mannose","Choline Fenofibrate","Canagliflozin hemihydrate","Diclofenac acid","Tulobuterol hydrochloride","Flurbiprofen Axetil"]
[null,"g","Empty","S5658","S5669","S5713","S5733","S5767","S5816","S5927","S6115","S6409","S6459","Empty"]
[{"$nulls":3},"Omeprazole Sodium","Isoxsuprine hydrochloride","Pravastatin","Stearic acid","Aliskiren","Pyrvinium","Proguanil","Pyridoxal 5′-phosphate hydrate","Zucapsaicin","Nifurtimox"]
[null,"h","Empty","S5659","S5670","S5714","S5735","S5780","S5821","S5939","S6118","S6410","S6476","Empty"]
[{"$nulls":3},"Emedastine","Chloropyramine hydrochloride","lurasidone","Midodrine","Prazosin","Linoleic acid","Bendamustine (SDX105)","Terpinen-4-ol","Clemizole","Eicosapentaenoic Acid"]
[]
[]
[]
[null,"Plate layout: L8000-18"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S6484","S7059","S7252","S7470","S7660","S7783","S7856","S7975","S8067","S8183","Empty"]
[{"$nulls":3},"uridine triacetate","Tezacaftor (VX-661)","Selinexor (KPT-330)","Triapine","Obeticholic Acid","Combretastatin A4","Tenofovir Alafenamide (GS-7340)","Favipiravir (T-705)","Vorapaxar (MK-5348)","Pimavanserin tartrate"]
[null,"b","Empty","S6588","S7077","S7280","S7505","S7663","S7784","S7858","S7998","S8101","S8205","Empty"]
[{"$nulls":3},"Methylprednisolone hemisuccinate","Cilengitide trifluoroacetate","Edoxaban tosylate Monohydrate","(S)-crizotinib","Ruboxistaurin (LY333531) HCl","Fumagillin","Dibutyryl-cAMP (Bucladesine)","Entrectinib (RXDX-101)","CB-5083","Enasidenib (AG-221)"]
[null,"c","Empty","S6590","S7083","S7297","S7536","S7668","S7786","S7867","S8016","S8116","S8206","Empty"]
[{"$nulls":3},"Hydrocortisone butyrate","Ceritinib (LDK378)","Osimertinib (AZD9291)","Lorlatinib (PF-6463922)","Picropodophyllin (PPP)","Erlotinib (OSI-774)","Oleuropein","Vonoprazan Fumarate (TAK-438)","Acalabrutinib (ACP-196)","Ivosidenib (AG-120)"]
[null,"d","Empty","S6601","S7091","S7303","S7559","S7678","S7787","S7935","Empty","S8133","S8294","Empty"]
[{"$nulls":3},"(±)-Equol","Zotarolimus (ABT-578)","Rilpivirine","Darolutamide (ODM-201)","Sacubitril/valsartan (LCZ696)","Docetaxel Trihydrate","Y-39983 HCl",null,"Resiquimod (R-848)","Olmutinib (BI 1482694)"]
[null,"e","Empty","S6614","S7156","S7397","S7579","S7721","S7810","S7952","S8034","S8134","S8362","Empty"]
[{"$nulls":3},"Fursultiamine","Marimastat (BB-2516)","Sorafenib (BAY 43-9006)","Ledipasvir (GS5885)","Monomethyl auristatin E (MMAE)","Afatinib (BIBW2992) Dimaleate","Ozanimod (RPC1063)","Apremilast (CC-10004)","Radotinib","Tucatinib"]
[null,"f","Empty","S7007","S7158","S7417","S7625","S7754","S7818","S7953","S8041","S8135","S8401","Empty"]
[{"$nulls":3},"Binimetinib (MEK162)","Abemaciclib mesylate (LY2835219)","Puromycin (CL13900) 2HCl","Niraparib (MK-4827) tosylate","Gilteritinib (ASP2215)","Pexidartinib (PLX3397)","ETC-1002","Cobimetinib (GDC-0973)","Riociguat (BAY 63-2521)","Erdafitinib (JNJ-42756493)"]
[null,"g","Empty","S7025","S7160","S7440","S7633","S7781","S7834","S7954","S8048","S8136","S8432","Empty"]
[{"$nulls":3},"Embelin","Glasdegib (PF-04449913)","Ribociclib (LEE011)","Lomitapide Mesylate","Sunitinib (SU11248)","Cyclo (-RGDfK)","CP21R7 (CP21)","Venetoclax (ABT-199)","Sivelestat (ONO-5046)","Troglitazone (CS-045)"]
[null,"h","Empty","S7028","S7179","Empty","S7650","S7782","S7844","S7960","S8051","S8144","S8539","Empty"]
[{"$nulls":3},"Duvelisib (IPI-145)","Siponimod (BAF312)",null,"Peficitinib (ASP015K)","Dasatinib Monohydrate","Cyclo(RGDyK)","Larotrectinib (LOXO-101) sulfate","Macitentan (ACT 064992)","Halofuginone","TAS-102"]
[]
[]
[]
[null,"Plate layout: L8000-19"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S8558","S9002","S9143","S9368","S9510","S8781","S9123","S9294","S6848","S3141","Empty"]
[{"$nulls":3},"Tofogliflozin(CSG 452)","L-Fucose","Ammonium Glycyrrhizate","ADP","Protriptyline hydrochloride","Selpercatinib (LOXO-292)","Eriodictyol","Gelsemine","3'-Fluoro-3'-deoxythymidine (Alovudine)","Maleimide"]
[null,"b","Empty","S8567","S9007","S9179","S9382","S4421","S9015","S9183","S9416","S0088","S5248","Empty"]
[{"$nulls":3},"Tucidinostat (Chidamide)","2'-deoxyguanosine","Catharanthine hemitartrate","Thymine","Josamycin","Homoharringtonine (CGX-635)","Ruscogenin","Triptonide","Pemigatinib (INCB054828)","Apatinib"]
[null,"c","Empty","S8594","S9032","S9193","S9413","S6589","S9024","S9192","S9519","S2440","S6948","Empty"]
[{"$nulls":3},"Tirofiban Hydrochloride","Sanguinarine","Aristolochic acid A","Yangonin","Norethisterone Enanthate","3-O-Acetyl-11-keto-β-boswellic acid (AKBA)","Vitexin","Fadrozole (CGS16949A)","Vindesine sulfate","Lanreotide"]
[null,"d","Empty","S8615","S9042","S9240","S9459","S6593","S9050","S9224","S2307","S3273","S6958","Empty"]
[{"$nulls":3},"Sodium dichloroacetate (DCA)","Wedelolactone","Isofraxidin","Mecamylamine Hydrochloride","Methylprednisolone sodium succinate","Boldine","Dehydroandrographolide Succinate","Roquinimex","Hypericin","Treosulfan"]
[null,"e","Empty","S8726","S9046","S9249","S9463","S6626","S9086","S9248","S2426","S6852","S9521","Empty"]
[{"$nulls":3},"Anlotinib (AL3818) dihydrochloride","Berberine","Securinine","Demecarium Bromide","Brequinar (DUP785)","Dihydrocapsaicin","Homoorientin","Tirapazamine","Gossypol","Pentostatin"]
[null,"f","Empty","S8757","S9063","S9321","S9502","S6631","S9102","S9270","S6676","S0323","S9712","Empty"]
[{"$nulls":3},"Ripretinib (DCC-2618)","Harringtonine","Topotecan","Madecassic acid","Belotecan (CKD-602) hydrochloride","Magnolin","Dracohodin perochlorate","Ebselen","Antineoplaston A10","Fluzoparib (SHR-3162)"]
[null,"g","Empty","S8791","S9140","S9338","Empty","S6742","S9110","S9285","S2288","S1198","S4418","Empty"]
[{"$nulls":3},"Zanubrutinib (BGB-3111)","Pulegone","Octyl gallate",null,"Etofenamate","Morin","Fargesin","Rubitecan","Irinotecan (CPT-11)","Phenol Red sodium salt"]
[null,"h","Empty","S8817","S9141","S9354","S9507","Empty","S9111","S9288","S2447","S1421","S4432","Empty"]
[{"$nulls":3},"Almonertinib (HS-10296)","Berbamine","Oxalic acid","(−)-Norepinephrine",null,"Isorhamnetin","Casticin","Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222)","Staurosporine (AM-2282)","Ixazomib Citrate (MLN9708)"]
[]
[]
[]
[null,"Plate layout: L8000-20"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4447","S5026","Empty","E0190","E0704","S7048","S3020","S8942","P1005","E2944","Empty"]
[{"$nulls":3},"Pipobroman","Irinotecan hydrochloride",null,"Invert sugar","Esaxerenone (CS-3150)","Talazoparib (BMN 673)","Romidepsin","Suramin sodium salt","Abarelix Acetate","Norepinephrine hydrochloride"]
[null,"b","Empty","S4484","S5080","S5860","E0245","E0707","S7108","S6594","S8955","P1109","E4010","Empty"]
[{"$nulls":3},"Trametinib DMSO solvate","Neticonazole","Larotrectinib","Rhamnose","Nomegestrol Acetate","Encorafenib (LGX818)","Liarozole dihydrochloride","Sotorasib (AMG510) racemate","Linaclotide","L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride"]
[null,"c","Empty","S4489","S5184","S5958","Empty","E0814","S8162","S6984","S8999","E0359","S9865","Empty"]
[{"$nulls":3},"Tetraethylammonium chloride","Dexamethasone palmitate","Metformin",null,"Masitinib mesylate","Upadacitinib (ABT-494)","Dianhydrogalactitol (VAL-083)","Exatecan Mesylate","Evocalcet","CB-5339"]
[null,"d","Empty","S4895","S5187","S5971","E0527","Empty","S8553","S7930","S9522","E1310","E4467","Empty"]
[{"$nulls":3},"Nilotinib hydrochloride monohydrate","Ribociclib hydrochloride","Pemetrexed","Norgestimate",null,"Avapritinib (BLU-285)","Ixabepilone (BMS-247550)","Valrubicin","DPCPX","Temozolomide Acid"]
[null,"e","Empty","S4929","S5188","S8932","E0528","E2516","Empty","S8064","S9702","E1410","E4474","Empty"]
[{"$nulls":3},"Enasidenib Mesylate","Ribociclib succinate","Remdesivir (GS-5734)","Flecainide","Doxorubicin",null,"Midostaurin (PKC412)","Finerenone","Fluspirilene","Infigratinib Phosphate"]
[null,"f","Empty","S4947","S5190","S9783","E0530","P1110","S1217","S8716","S9726","E2873","E1445","Empty"]
[{"$nulls":3},"Regorafenib Hydrochloride","Crizotinib hydrochloride","6-Aminonicotinamide","Prednicarbate","Etelcalcetide HCl","Cyclophosphamide","Pralsetinib (BLU-667)","Rimiducid (AP1903)","Laropiprant","Palovarotene"]
[null,"g","Empty","S4948","S5195","S2089","E0609","Empty","S2221","S8830","E0742","E2874","S4684","Empty"]
[{"$nulls":3},"Rucaparib","Rucaparib Camsylate","Fenoldopam","Methyl methanesulfonate",null,"Apatinib (YN968D1) mesylate","Sotorasib (AMG510)","Melengestrol Acetate","Sofpironium bromide","Sildenafil"]
[null,"h","Empty","S4967","S5738","S9973","E0650","S1469","S2345","S8926","E2438","E2876","Empty","Empty"]
[{"$nulls":3},"Ceritinib dihydrochloride","Megestrol","Flumatinib (HH-GV-678)","γ-Terpinene","Calcifediol","Podophyllotoxin (Podofilox)","Valemetostat (DS-3201)","Ginsenoside Rg3","pemafibrate"]
[]
[]
[]
[null,"Plate layout: L8000-21"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1037","S1345","S1648","S2008","S2527","S3146","S3861","S4108","S4236","S4606","Empty"]
[{"$nulls":3},"Perifosine (KRX-0401)","Granisetron HCl","Cytarabine (U-19920A)","Taurine","Methacycline HCl","Tripelennamine HCl","Sodium Demethylcantharidate","Clodronate Disodium","Proflavine Hemisulfate","Glutathione"]
[null,"b","Empty","S1116","S1375","Empty","S2048","S2539","S3148","S3963","S4117","S4245","S4653","Empty"]
[{"$nulls":3},"Palbociclib (PD-0332991) HCl","Dorzolamide HCl",null,"Clindamycin Phosphate","Lomefloxacin HCl","Ibandronate sodium monohydrate","DL-Glutamine","Histamine Phosphate","Sodium ascorbate","L-Ornithine hydrochloride"]
[null,"c","Empty","S1135","S1440","S1853","S2076","S3013","S3174","S3973","S4121","S4254","S4671","Empty"]
[{"$nulls":3},"Pemetrexed (LY-231514) disodium","Varenicline Tartrate (CP 526555-18)","Penicillamine","Lisinopril dihydrate","Plerixafor (AMD3100) 8HCl","L-Arginine HCl (L-Arg)","L-SelenoMethionine","Succinylcholine Chloride Dihydrate","Apramycin Sulfate","Cefradine"]
[null,"d","Empty","S1149","S1506","S1857","S2129","S3048","S3649","S4008","S4127","S4298","Empty","Empty"]
[{"$nulls":3},"Gemcitabine (LY-188011) HCl","Perindopril Erbumine","Etidronate","Fudosteine","Solifenacin succinate","Ceftazidime","Pemirolast potassium","Terbutaline Sulfate","Amifostine trihydrate"]
[null,"e","Empty","Empty","S1516","S1875","S2133","S3050","S3662","S4027","S4144","S4360","S4700","Empty"]
[{"$nulls":4},"Cidofovir","Tranexamic Acid","Gabapentin","Palonosetron HCl","Pirenzepine dihydrochloride","Flavoxate HCl","Amprolium HCl","Tolmetin Sodium","4-Aminobutyric acid (GABA)"]
[null,"f","Empty","Empty","S1518","S1984","S2462","S3056","S3667","S4028","S4157","S4430","S4740","Empty"]
[{"$nulls":4},"Ibuprofen Lysine","Ticlopidine HCl","Donepezil HCl","Miltefosine","Imipenem","Dexamethasone Sodium Phosphate","Chloroquine diphosphate","Hydroxychloroquine Sulfate (NSC 4375)","Sodium ferulate"]
[null,"g","Empty","S1311","S1579","S1995","S2490","S3058","S3748","S4030","S4158","S4575","S4741","Empty"]
[{"$nulls":3},"Pamidronate Disodium","Palbociclib (PD0332991) Isethionate","Procarbazine HCl","Neostigmine Bromide","Danofloxacin Mesylate","Acamprosate Calcium","Gentamicin Sulfate","Ceftriaxone disodium salt hemi (heptahydrate)","Pralidoxime chloride","Danshensu"]
[null,"h","Empty","S1339","S1624","S1999","S2507","S3072","S3752","S4094","S4183","S4582","S4993","Empty"]
[{"$nulls":3},"Galanthamine HBr","Alendronate sodium trihydrate","Sodium butyrate","Salbutamol Sulfate","(R)-baclofen","isoleucine","Tetramisole HCl","Paromomycin Sulfate","Eflornithine (MDL-71782) hydrochloride hydrate","Timonacic"]
[]
[]
[]
[null,"Plate layout: L8000-22"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S5097","S5545","S9353","P1084","Empty","S2542","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Methotrexate disodium","DL-Serine","L-serine","Desmopressin Acetate",null,"Phenformin (NSC-756501) HCl"]
[null,"b","Empty","S5131","S5660","P1011","P1085","S3096","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Homotaurine","Clodronate disodium tetrahydrate","Eptifibatide Acetate","Angiotensin II human Acetate","L-Histidine monohydrochloride monohydrate"]
[null,"c","Empty","S5136","S5706","Empty","Empty","S1314","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Calcium folinate","Edetate Trisodium",null,null,"Zoledronic acid (ZOL 446)"]
[null,"d","Empty","S5267","S6023","P1017","S1671","S6289","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Nylidrin Hydrochloride","Creatine monohydrate","Octreotide (SMS 201-995) acetate","(6-)ε-​Aminocaproic acid","Gentamicin"]
[null,"e","Empty","S5384","S6445","P1025","S3076","S6872","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"UTP Trisodium Salt","Chlorophyllin (sodium copper salt)","Atosiban Acetate","Foscarnet Sodium","Merbromin"]
[null,"f","Empty","S5524","S6488","P1030","S4519","E0532","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Spermine Tetrahydrochloride","Gadoxetate sodium","Salmon Calcitonin Acetate","Citric acid trilithium salt tetrahydrate","Menotropin"]
[null,"g","Empty","S5526","Empty","P1039","S2441","E2638","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"β-Alanine",null,"Somatostatin Acetate","Estramustine phosphate sodium","Tricine"]
[null,"h","Empty","S5533","S7785","Empty","P1088","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Tobramycin sulfate","Pemetrexed Disodium Hydrate",null,"Lanreotide acetate"]
[]
[]
[]
[null,"Plate layout: L8000-23"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1023","S1507","S1837","S2206","S2920","S4262","S8229","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Erlotinib (OSI-774) HCl","Irbesartan","Flubendazole","Fostamatinib (R788) disodium","Mozavaptan","Ebastine","Brigatinib (AP26113)"]
[null,"b","Empty","S1046","S1509","S1851","S2251","S3059","S4605","S5098","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Vandetanib (ZD6474)","Norfloxacin","Oxibendazole","(-)-Huperzine A (HupA)","Enrofloxacin","Folic acid","Gefitinib hydrochloride"]
[null,"c","Empty","S1211","S1615","S1977","S2292","S3770","S4642","S1502","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Imiquimod (R-837)","Risperidone","Sarafloxacin HCl","Diosmin","Sodium Aescinate","Dolutegravir Sodium","Cephalexin"]
[null,"d","Empty","S1288","S1617","S1986","S2476","S3801","S5018","S4482","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Camptothecin (NSC-100880)","Sulfapyridine","Meclizine 2HCl","Itraconazole (R 51211)","Sodium Houttuyfonate","Mebhydrolin napadisylate","Palbociclib"]
[null,"e","Empty","S1353","S1642","S2035","S2530","S3821","S5232","E0524","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Ketoconazole (R 41400)","Methyldopa","Epalrestat (ONO-2235)","7-Aminocephalosporanic acid","Nuciferine","Alectinib (CH5424802) hydrochloride","Spinosad"]
[null,"f","Empty","S1424","S1698","S2047","S2582","S3891","S5677","S9464","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Prazosin HCl","Torsemide","Lornoxicam","Trazodone HCl","Vincamine","Xanthopterin Hydrate","Tranylcypromine Sulfate"]
[null,"g","Empty","S1463","S1707","S2110","S2597","S4033","S7128","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Ofloxacin","Eplerenone (CGP 30083)","Vinpocetine","Oseltamivir Phosphate","Sennoside A","Tazemetostat (EPZ-6438)"]
[null,"h","Empty","S1464","S1724","S2150","S2788","S4126","S7756","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Marbofloxacin","Paliperidone","Neratinib (HKI-272)","Capmatinib (INCB28060)","Retinyl (Vitamin A) Palmitate","Indoximod (NLG-8189）"]
[]
[]
[]
[null,"Plate layout: L8000-24"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","Empty","S5650","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":4},"Sodium Hyaluronate"]
[null,"b","Empty","S1911","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Disodium Cromoglycate"]
[null,"c","Empty","S2106","S2095","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Azasetron HCl","Fosinopril Sodium"]
[null,"d","Empty","S2562","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Hydralazine HCl"]
[null,"e","Empty","S4067","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Deferiprone"]
[null,"f","Empty","S4226","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Minocycline (CL 59806) HCl"]
[null,"g","Empty","S4694","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Alosetron Hydrochloride"]
[null,"h","Empty","S8030","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Plerixafor (AMD3100)"]

{"sheet":"Chemical Data-1728 cpds","index":1,"n_rows":1729,"n_cols":23,"rows_kept":1729}
["Cat","Name","Plate Location","Rack Number","Formulation","Target","Pathway","Information","M.w.","CAS Number","DMSO (mg/mL)Max Solubility","DMSO (mM)Max Solubility","Water (mg/mL)Max Solubility","Water (mM)Max Solubility","URL","Formula","Form","Synonyms","SMILES","ALogP","HBA_Count","HBD_Count","RotatableBond"]
["S1005","Axitinib (AG 013736)","a2","L8000-01","in 10mM DMSO","c-Kit,PDGFR,VEGFR","Protein Tyrosine Kinase","Axitinib (AG 013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively.",386.47,"319460-85-0",{"v":35,"d":"35.00"},90.56,"<1","N/A","http://selleckchem.com/products/Axitinib.html","C22H18N4OS","free base","AG 013736","CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=N[NH]3)\\C=C\\C4=CC=CC=N4",4.492,3,2,5]
["S1007","Roxadustat (FG-4592)","b2","L8000-01","in 10mM DMSO","Ferroptosis,HIF","Angiogenesis","Roxadustat (FG-4592) is an HIF-α prolyl hydroxylase inhibitor in a cell-free assay, stabilizes HIF-2 and induces EPO production. Roxadustat potentiates RSL3 induced ferroptosis. Phase 3.",352.34,"808118-40-3",{"v":70,"d":"70.00"},198.67,"<1","N/A","http://selleckchem.com/products/fg-4592.html","C19H16N2O5","free base","ASP1517","CC1=NC(=C(O)C2=C1C=C(OC3=CC=CC=C3)C=C2)C(=O)NCC(O)=O",2.306,4,2,5]
["S1008","Selumetinib (AZD6244)","c2","L8000-01","in 10mM DMSO","Apoptosis related,MEK","MAPK","Selumetinib (AZD6244, ARRY-142886) is a potent, highly selective MEK inhibitor with IC50 of 14 nM for MEK1 and Kd value of 530 nM for MEK2. It  also inhibits ERK1/2 phosphorylation with IC50 of 10 nM, no inhibition to p38α, MKK6, EGFR, ErbB2, ERK2, B-Raf, etc. Selumetinib suppresses cell proliferation, migration and trigger apoptosis. Phase 3.",457.68,"606143-52-6",{"v":91,"d":"91.00"},198.83,"<1","N/A","http://selleckchem.com/products/AZD6244.html","C17H15BrClFN4O3","free base","ARRY-142886","C[N]1C=NC2=C(F)C(=C(C=C12)C(=O)NOCCO)NC3=CC=C(Br)C=C3Cl",3.234,3,3,6]
["S1010","Nintedanib (BIBF 1120)","d2","L8000-01","in 10mM DMSO","FGFR,PDGFR,Src,VEGFR","Protein Tyrosine Kinase","Nintedanib (BIBF 1120, Intedanib, Vargatef, Ofev) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM in cell-free assays. Phase 3.",539.62,"656247-17-5",{"v":6,"d":"6.00"},11.12,"<1","N/A","http://selleckchem.com/products/BIBF1120.html","C31H33N5O4","free base","Intedanib, Vargatef, Ofev","COC(=O)C1=CC=C\\2C(=C1)NC(=O)C2=C(NC3=CC=C(C=C3)N(C)C(=O)CN4CCN(C)CC4)/C5=CC=CC=C5",2.965,4,2,8]
["S1011","Afatinib (BIBW2992)","e2","L8000-01","in 10mM DMSO","Autophagy,EGFR,HER2","Protein Tyrosine Kinase","Afatinib (BIBW2992) inhibits EGFR/ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively. Afatinib induces autophagy.",485.94,"850140-72-6",{"v":97,"d":"97.00"},199.61,"<1","N/A","http://selleckchem.com/products/BIBW2992.html","C24H25ClFN5O3","Free Base","BIBW2992","CN(C)C/C=C/C(=O)NC1=CC2=C(NC3=CC=C(F)C(=C3)Cl)N=CN=C2C=C1OC4CCOC4",3.917,5,2,8]
["S1013","Bortezomib (PS-341)","f2","L8000-01","in 10mM DMSO","Autophagy,Cathepsin B,Cysteine Protease,ERK,NF-κB,Proteasome","Proteases","Bortezomib (PS-341, Velcade, LDP-341, MLM341, NSC 681239) is a potent 20S proteasome inhibitor with Ki of 0.6 nM. It exhibits favorable selectivity towards tumor cells over normal cells. Bortezomib (PS-341) inhibits NF-κB and induces ERK phosphorylation to suppress cathepsin B and inhibit the catalytic process of autophagy in ovarian cancer and other solid tumors.",384.24,"179324-69-7",{"v":76,"d":"76.00"},197.79,"<1","N/A","http://selleckchem.com/products/Bortezomib.html","C19H25BN4O4","Free Base","Velcade, LDP-341, MLM341, NSC 681239,PS-341","CC(C)CC(NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)B(O)O",2.183,4,2,9]
["S1014","Bosutinib (SKI-606)","g2","L8000-01","in 10mM DMSO","Autophagy,Bcr-Abl,ERK,S6 Kinase,Src,STAT","Angiogenesis","Bosutinib (SKI-606) is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM in cell-free assays, respectively. Bosutinib also effectively decreases the activity of PI3K/AKT/mTOR, MAPK/ERK and JAK/STAT3 signaling pathways by blocking the phosphorylation levels of p-ERK, p-S6, and p-STAT3. Bosutinib promotes autophagy.",530.45,"380843-75-4",{"v":100,"d":"100.00"},188.52,"<1","N/A","http://selleckchem.com/products/Bosutinib.html","C26H29Cl2N5O3","free base","SKI-606","COC1=C(Cl)C=C(Cl)C(=C1)NC2=C(C=NC3=CC(=C(OC)C=C23)OCCCN4CCN(C)CC4)C#N",4.883,4,1,9]
["S1021","Dasatinib (BMS-354825)","h2","L8000-01","in 10mM DMSO","Apoptosis related,Autophagy,Bcr-Abl,c-Kit,Src","Angiogenesis","Dasatinib (BMS-354825) is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively. Dasatinib induces autophagy and apoptosis with anti-tumor activity.",488.01,"302962-49-8",{"v":98,"d":"98.00"},200.82,"<1","N/A","http://selleckchem.com/products/Dasatinib.html","C22H26ClN7O2S","free base","BMS-354825","CC1=NC(=CC(=N1)N2CCN(CCO)CC2)NC3=NC=C(S3)C(=O)NC4=C(Cl)C=CC=C4C",3.439,4,3,7]
["S1022","Ridaforolimus (Deforolimus, MK-8669)","a3","L8000-01","in 10mM DMSO","FKBP,mTOR","PI3K/Akt/mTOR","Ridaforolimus (Deforolimus, MK-8669, AP23573) is a selective mTOR inhibitor with IC50 of 0.2 nM in HT-1080 cell line; while not classified as a prodrug, mTOR inhibition and FKBP12 binding is similar to rapamycin. Phase 3.",990.21,"572924-54-0",{"v":198,"d":"198.00"},199.96,"<1","N/A","http://selleckchem.com/products/Deforolimus.html","C53H84NO14P","free base","AP23573","COC1CC(CCC1O[P](C)(C)=O)CC(C)C2CC(=O)C(C)\\C=C(C)\\C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC",6.303,12,1,8]
["S1025","Gefitinib (ZD1839)","b3","L8000-01","in 10mM DMSO","Apoptosis related,Autophagy,EGFR","Protein Tyrosine Kinase","Gefitinib (ZD-1839, Iressa) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively. Gefitinib promotes autophagy and apoptosis of lung cancer cells via blockade of the PI3K/AKT/mTOR pathway.",{"v":446.9,"d":"446.90"},"184475-35-2",{"v":89,"d":"89.00"},199.15,"<1","N/A","http://selleckchem.com/products/Gefitinib.html","C22H24ClFN4O3","free base","Iressa,ZD1839","COC1=C(OCCCN2CCOCC2)C=C3C(=NC=NC3=C1)NC4=CC=C(F)C(=C4)Cl",4.203,5,1,8]
["S1026","Imatinib (STI571) Mesylate","c3","L8000-01","in 10mM DMSO","Autophagy,Bcr-Abl,c-Kit,PDGFR","Protein Tyrosine Kinase","Imatinib (STI571, CGP057148B, Gleevec) Mesylate is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib Mesylate (STI571) induces autophagy.",589.71,"220127-57-1",{"v":118,"d":"118.00"},{"v":200.1,"d":"200.10"},{"v":118,"d":"118.00"},{"v":200.1,"d":"200.10"},"http://selleckchem.com/products/Imatinib-Mesylate.html","C29H31N7O.CH4SO3","Mesylate","Gleevec, Glivec, CGP-57148B,STI571","CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC=C(C)C(=C3)NC4=NC=CC(=N4)C5=CC=CN=C5.C[S](O)(=O)=O",3.806,4,2,7]
["S1028","Lapatinib (GW-572016) Ditosylate","d3","L8000-01","in 10mM DMSO","EGFR,HER2","Protein Tyrosine Kinase","Lapatinib (GW-572016) Ditosylate is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively.",925.46,"388082-77-7",{"v":100,"d":"100.00"},108.05,"<1","N/A","http://selleckchem.com/products/Lapatinib-Ditosylate.html","C29H26ClFN4O4S.2C7H8O3S","Ditosylat","GW-572016","CC1=CC=C(C=C1)[S](O)(=O)=O.CC2=CC=C(C=C2)[S](O)(=O)=O.C[S](=O)(=O)CCNCC3=CC=C(O3)C4=CC=C5N=CN=C(NC6=CC=C(OCC7=CC=CC(=C7)F)C(=C6)Cl)C5=C4",9.339,6,2,13]
["S1029","Lenalidomide (CC-5013)","e3","L8000-01","in 10mM DMSO","Apoptosis related,Caspase,E3 Ligase ,E3 ligase Ligand,TNF-alpha,VEGFR","Ubiquitin","Lenalidomide (CC-5013) is a TNF-α secretion inhibitor with IC50 of 13 nM in PBMCs. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide promotes cleaved caspase-3 expression and inhibit VEGF expression and induces apoptosis.",259.26,"191732-72-6",{"v":52,"d":"52.00"},200.57,"<1","N/A","https://www.selleckchem.com/products/lenalidomide-s1029.html","C13H13N3O3","free base","CC-5013","NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1",-0.515,3,2,1]
["S1030","Panobinostat (LBH589)","f3","L8000-01","in 10mM DMSO","Apoptosis related,Autophagy,HDAC,HIV Protease","Epigenetics","Panobinostat (LBH589, NVP-LBH589) is a novel broad-spectrum HDAC inhibitor with IC50 of 5 nM in a cell-free assay. Panobinostat (LBH589) induces autophagy and apoptosis. Panobinostat effectively disrupts HIV latency in vivo. Phase 3.",349.43,"404950-80-7",{"v":69,"d":"69.00"},197.46,"<1","N/A","http://selleckchem.com/products/LBH-589.html","C21H23N3O2","Free Base","NVP-LBH589","CC1=C(CCNCC2=CC=C(\\C=C\\C(=O)NO)C=C2)C3=C([NH]1)C=CC=C3",3.194,1,3,7]
["S1033","Nilotinib (AMN-107)","g3","L8000-01","in 10mM DMSO","AMPK,Autophagy,Bcr-Abl","Angiogenesis","Nilotinib (AMN-107) is a selective Bcr-Abl inhibitor with IC50 less than 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.",529.52,"641571-10-0",{"v":27,"d":"27.00"},50.99,"<1","N/A","http://selleckchem.com/products/Nilotinib.html","C28H22F3N7O","free base","AMN-107","CC1=C[N](C=N1)C2=CC(=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C)C(=C3)NC4=NC=CC(=N4)C5=CN=CC=C5",5.084,5,2,7]
["S1035","Pazopanib HCl (GW786034 HCl)","h3","L8000-01","in 10mM DMSO","Autophagy,c-Kit,CSF-1R,FGFR,PDGFR,VEGFR","Protein Tyrosine Kinase","Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively. Pazopanib induces autophagic Type II cell death.",473.98,"635702-64-6",{"v":17,"d":"17.00"},35.87,"<1","N/A","http://selleckchem.com/products/Pazopanib-Hydrochloride.html","C21H23N7O2S.HCl","Hydrochloride","GW786034 HCl","Cl.C[N]1N=C2C=C(C=CC2=C1C)N(C)C3=NC(=NC=C3)NC4=CC=C(C)C(=C4)[S](N)(=O)=O",4.123,5,2,5]
["S1039","Rapamycin (AY-22989)","a4","L8000-01","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,Autophagy,mTOR","PI3K/Akt/mTOR","Rapamycin (AY-22989, Rapamune, Sirolimus, NSC-2260804,AY-22989) is a specific mTOR inhibitor with IC50 of ~0.1 nM HEK293 cells.",914.18,"53123-88-9",{"v":20,"d":"20.00"},21.88,"<1","N/A","http://selleckchem.com/products/Rapamycin.html","C51H79NO13","free base","Rapamune, Sirolimus, NSC-2260804,AY-22989","COC1CC(CCC1O)CC(C)C2CC(=O)C(C)\\C=C(/C)C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC",6.295,10,2,6]
["S1040","Sorafenib (BAY 43-9006) tosylate","b4","L8000-01","in 10mM DMSO","Apoptosis related,Autophagy,c-Kit,Ferroptosis,FGFR,FLT3,PDGFR,Raf,VEGFR","MAPK","Sorafenib tosylate (BAY 43-9006 tosylate,NSC-724772 tosylate)  is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib Tosylate inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib Tosylate induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.",637.03,"475207-59-1",{"v":127,"d":"127.00"},199.36,0.01,0.02,"http://selleckchem.com/products/Sorafenib-Tosylate.html","C21H16ClF3N4O3.C7H8O3S","Tosylate","BAY 43-9006 tosylate,NSC-724772 tosylate","CNC(=O)C1=CC(=CC=N1)OC2=CC=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2.CC4=CC=C(C=C4)[S](O)(=O)=O",5.824,4,3,7]
["S1042","Sunitinib (SU11248) malate","c4","L8000-01","in 10mM DMSO","Apoptosis related,c-Kit,IRE1,Mitophagy,PDGFR,VEGFR","Protein Tyrosine Kinase","Sunitinib (SU11248) malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM in cell-free assays, and also inhibits c-Kit. Sunitinib Malate effectively inhibits autophosphorylation of Ire1α. Sunitinib Malate increases both death receptor and mitochondrial-dependent apoptosis.",532.56,"341031-54-7",{"v":15,"d":"15.00"},28.17,"<1","N/A","http://selleckchem.com/products/Sunitinib-Malate-(Sutent).html","C22H27FN4O2.C4H6O5","Malate","N/A","CCN(CC)CCNC(=O)C1=C(C)[NH]C(=C1C)/C=C/2C(=O)NC3=CC=C(F)C=C23.OC(CC(O)=O)C(O)=O",-1.049,4,4,10]
["S1044","Temsirolimus (CCI-779)","d4","L8000-01","in 10mM DMSO","Apoptosis related,Autophagy,mTOR","PI3K/Akt/mTOR","Temsirolimus (CCI-779, NSC 683864) is a specific mTOR inhibitor with IC50 of 1.76 μM in a cell-free assay. Temsirolimus induces autophagy and apoptosis.",1030.29,"162635-04-3",{"v":67,"d":"67.00"},65.03,"<1","N/A","http://selleckchem.com/products/Temsirolimus.html","C56H87NO16","free base","NSC 683864,CCI-779","COC1CC(CCC1OC(=O)C(C)(CO)CO)CC(C)C2CC(=O)C(C)\\C=C(C)\\C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC",6.039,12,3,11]
["S1047","Vorinostat (SAHA)","e4","L8000-01","in 10mM DMSO","Autophagy,HDAC,HPV","Epigenetics","Vorinostat (SAHA,MK0683, Suberoylanilide hydroxamic acid, Zolinza) is an HDAC inhibitor with IC50 of ~10 nM in a cell-free assay. Vorinostat abrogates productive HPV-18 DNA amplification.",{"v":264.3,"d":"264.30"},"149647-78-9",{"v":52,"d":"52.00"},196.75,"<1","N/A","http://selleckchem.com/products/Vorinostat-saha.html","C14H20N2O3","free base","SAHA,MK0683, Suberoylanilide hydroxamic acid, Zolinza","ONC(=O)CCCCCCC(=O)NC1=CC=CC=C1",2.005,2,2,8]
["S1053","Entinostat (MS-275)","f4","L8000-01","in 10mM DMSO","Apoptosis related,Autophagy,HDAC","Epigenetics","Entinostat (MS-275, SNDX-275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM in cell-free assays, compared with HDACs 4, 6, 8, and 10. Entinostat induces autophagy and apoptosis. Phase 3.",376.41,"209783-80-2",{"v":75,"d":"75.00"},199.25,"<1","N/A","http://selleckchem.com/products/MS-275.html","C21H20N4O3","free base","SNDX-275","NC1=CC=CC=C1NC(=O)C2=CC=C(CNC(=O)OCC3=CN=CC=C3)C=C2",2.071,4,3,7]
["S1055","Enzastaurin (LY317615)","g4","L8000-01","in 10mM DMSO","PKC","TGF-beta/Smad","Enzastaurin (LY317615) is a potent PKCβ selective inhibitor with IC50 of 6 nM in cell-free assays, 6- to 20-fold selectivity against PKCα, PKCγ and PKCε. Phase 3.",515.61,"170364-57-5",{"v":30,"d":"30.00"},58.18,"<1","N/A","http://selleckchem.com/products/Enzastaurin.html","C32H29N5O2","free base","N/A","C[N]1C=C(C2=CC=CC=C12)C3=C(C(=O)NC3=O)C4=C[N](C5CCN(CC5)CC6=NC=CC=C6)C7=CC=CC=C47",{"v":4.32,"d":"4.320"},3,1,5]
["S1060","Olaparib (AZD2281)","h4","L8000-01","in 10mM DMSO","Autophagy,Mitophagy,PARP","DNA Damage/DNA Repair","Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1. Olaparib induces significant autophagy that is associated with mitophagy in cells with BRCA mutations.",434.46,"763113-22-0",{"v":86,"d":"86.00"},197.95,"N/A","N/A","http://selleckchem.com/products/AZD2281(Olaparib).html","C24H23FN4O3","free base","Ku-0059436","FC1=C(C=C(CC2=NNC(=O)C3=C2C=CC=C3)C=C1)C(=O)N4CCN(CC4)C(=O)C5CC5",2.127,4,1,4]
["S1064","Masitinib (AB1010)","a5","L8000-01","in 10mM DMSO","c-Kit,PDGFR","Protein Tyrosine Kinase","Masitinib is a novel inhibitor for Kit (c-Kit) and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms. Phase 3.",498.64,"790299-79-5",{"v":100,"d":"100.00"},200.55,"<1","N/A","http://selleckchem.com/products/Masitinib-(AB1010).html","C28H30N6OS","free base","N/A","CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC(=C(C)C=C3)NC4=NC(=CS4)C5=CC=CN=C5",4.475,3,2,7]
["S1068","Crizotinib (PF-02341066)","b5","L8000-01","in 10mM DMSO","ALK,Autophagy,c-Met,ROS1","Protein Tyrosine Kinase","Crizotinib (PF-02341066) is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM in cell-based assays, respectively. It is also a potent ROS1 inhibitor with Ki value less than 0.025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines.",450.34,"877399-52-5",{"v":9,"d":"9.00"},19.98,"<1","N/A","http://selleckchem.com/products/PF-2341066.html","C21H22Cl2FN5O","free base","PF-02341066","CC(OC1=C(N)N=CC(=C1)C2=C[N](N=C2)C3CCNCC3)C4=C(Cl)C=CC(=C4Cl)F",3.693,3,2,5]
["S1082","Vismodegib (GDC-0449)","c5","L8000-01","in 10mM DMSO","Hedgehog/Smoothened","Stem Cells & Wnt","Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay.",{"v":421.3,"d":"421.30"},"879085-55-9",{"v":84,"d":"84.00"},199.38,"<1","N/A","http://selleckchem.com/products/GDC-0449.html","C19H14Cl2N2O3S","free base","GDC-0449","C[S](=O)(=O)C1=CC=C(C(=C1)Cl)C(=O)NC2=CC(=C(Cl)C=C2)C3=NC=CC=C3",4.265,4,1,4]
["S1085","Belinostat (PXD101)","d5","L8000-01","in 10mM DMSO","Autophagy,HDAC","Epigenetics","Belinostat (PXD101, NSC726630, PX-105684) is a novel HDAC inhibitor with IC50 of 27 nM in a cell-free assay, with activity demonstrated in cisplatin-resistant tumors. Belinostat (PXD101) induces autophagy.",318.35,"866323-14-0",{"v":64,"d":"64.00"},201.04,"<1","N/A","http://selleckchem.com/products/Belinostat.html","C15H14N2O4S","free base","PXD101,NSC726630, PX-105684","ONC(=O)/C=C/C1=CC(=CC=C1)[S](=O)(=O)NC2=CC=CC=C2",{"v":1.8,"d":"1.800"},3,2,5]
["S1098","Rucaparib (AG-014699) phosphate","e5","L8000-01","in 10mM DMSO","PARP","DNA Damage/DNA Repair","Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains. Phase 3.",421.36,"459868-92-9",{"v":84,"d":"84.00"},199.35,"<1","N/A","http://selleckchem.com/products/AG-014699.html","C19H18FN3O.H3PO4","Phosphate","PF-01367338","CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=CC(=CC(=C34)[NH]2)F.O[P](O)(O)=O",{"v":2.49,"d":"2.490"},1,3,3]
["S1119","Cabozantinib (BMS-907351)","f5","L8000-01","in 10mM DMSO","Apoptosis related,Axl,c-Met,VEGFR","Protein Tyrosine Kinase","Cabozantinib (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively. Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway.",501.51,"849217-68-1",{"v":100,"d":"100.00"},{"v":199.4,"d":"199.40"},"<1","N/A","http://selleckchem.com/products/XL184.html","C28H24FN3O5","Free Base","XL184,BMS-907351","COC1=CC2=C(C=C1OC)C(=CC=N2)OC3=CC=C(NC(=O)C4(CC4)C(=O)NC5=CC=C(F)C=C5)C=C3",4.342,6,2,8]
["S1120","Everolimus (RAD001)","g5","L8000-01","in 10mM DMSO","Apoptosis related,Autophagy,FKBP,mTOR","PI3K/Akt/mTOR","Everolimus (RAD001, SDZ-RAD, Afinitor) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM in a cell-free assay. Everolimus induces cell apoptosis and autophagy and inhibits tumor cells proliferation.",958.22,"159351-69-6",{"v":100,"d":"100.00"},104.36,"<1","N/A","http://selleckchem.com/products/Everolimus(RAD001).html","C53H83NO14","free base","RAD001,SDZ-RAD, Afinitor","COC1CC(CCC1OCCO)CC(C)C2CC(=O)C(C)\\C=C(C)\\C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC",6.164,11,2,9]
["S1137","Malotilate","h5","L8000-01","in 10mM DMSO","Lipoxygenase","Metabolism","Malotilate (NKK105) is a drug used for the treatment of liver cirrhosis. Malotilate is a liver protein metabolism improved compound, which selectively inhibit the 5-lipoxygenase.",288.38,"59937-28-9",{"v":58,"d":"58.00"},201.12,"<1","N/A","http://selleckchem.com/products/Malotilate.html","C12H16O4S2","free base","NKK105","CC(C)OC(=O)C(C(=O)OC(C)C)=C1SC=CS1",2.363,4,0,6]
["S1144","Ivacaftor (VX-770)","a6","L8000-01","in 10mM DMSO","CFTR","Transmembrane Transporters","Ivacaftor (VX-770) is a selective potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM in fisher rat thyroid cells, respectively.",392.49,"873054-44-5",{"v":78,"d":"78.00"},198.73,"<1","N/A","http://selleckchem.com/products/VX-770.html","C24H28N2O3","free base","VX-770","CC(C)(C)C1=CC(=C(NC(=O)C2=CNC3=C(C=CC=C3)C2=O)C=C1O)C(C)(C)C",4.516,2,3,4]
["S1148","Docetaxel (RP56976)","b6","L8000-01","in 10mM DMSO","Microtubule Associated","Cytoskeletal Signaling","Docetaxel (RP56976, NSC 628503), an analog of paclitaxel, is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules.",807.88,"114977-28-5",{"v":100,"d":"100.00"},123.78,"<1","N/A","http://selleckchem.com/products/Docetaxel(Taxotere).html","C43H53NO14","Free Base","NSC 628503,RP56976","CC(=O)OC12COC1CC(O)C3(C)C2C(OC(=O)C4=CC=CC=C4)C5(O)CC(OC(=O)C(O)C(NC(=O)OC(C)(C)C)C6=CC=CC=C6)C(=C(C(O)C3=O)C5(C)C)C",2.586,10,4,13]
["S1150","Paclitaxel (NSC 125973)","c6","L8000-01","in 10mM DMSO","ADC Cytotoxin,Antineoplastic and Immunosuppressive Antibiotics,Autophagy,Microtubule Associated","Cytoskeletal Signaling","Paclitaxel (NSC 125973, PTX, Taxol, Onxal, Abraxane) is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.",853.91,"33069-62-4",{"v":171,"d":"171.00"},200.26,"<1","N/A","http://selleckchem.com/products/Paclitaxel(Taxol).html","C47H51NO14","free base","PTX, Taxol, Onxal, Abraxane,NSC 125973","CC(=O)OC1C(=O)C2(C)C(O)CC3OCC3(OC(C)=O)C2C(OC(=O)C4=CC=CC=C4)C5(O)CC(OC(=O)C(O)C(NC(=O)C6=CC=CC=C6)C7=CC=CC=C7)C(=C1C5(C)C)C",3.055,11,3,14]
["S1156","Capecitabine (RO 09-1978)","d6","L8000-01","in 10mM DMSO","Apoptosis related,DNA/RNA Synthesis","DNA Damage/DNA Repair","Capecitabine (RO 09-1978) is a tumor-selective fluoropyrimidine carbamate, which achieves higher intratumoral 5-FU level with lower toxicity than 5-FU. Capecitabine treatment of HCT-15 cells causes condensation of DNA and induces apoptosis.",359.35,"154361-50-9",{"v":72,"d":"72.00"},200.36,{"v":6,"d":"6.00"},{"v":16.7,"d":"16.70"},"http://selleckchem.com/products/Capecitabine(Xeloda).html","C15H22FN3O6","free base","RO 09-1978","CCCCCOC(=O)NC1=NC(=O)N(C=C1F)C2OC(C)C(O)C2O",{"v":0.82,"d":"0.820"},5,3,7]
["S1162","Pretomanid (PA-824)","e6","L8000-01","in 10mM DMSO","Bacterial","Microbiology","PA-824 is an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM.Phase 2.",359.26,"187235-37-6",{"v":72,"d":"72.00"},200.41,"<1","N/A","http://selleckchem.com/products/pa-824.html","C14H12F3N3O5","free base","N/A","[O-][N+](=O)C1=C[N]2CC(COC2=N1)OCC3=CC=C(OC(F)(F)F)C=C3",4.301,4,0,6]
["S1164","Lenvatinib (E7080)","f6","L8000-01","in 10mM DMSO","c-Kit,c-RET,FGFR,PDGFR,VEGFR","Protein Tyrosine Kinase","Lenvatinib (E7080) is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β in cell-free assays. Lenvatinib (E7080) also inhibits FGFR1-4, PDGFR, Kit (c-Kit), RET (c-RET), and shows potent antitumor activities. Phase 3.",426.85,"417716-92-8",{"v":40,"d":"40.00"},93.71,"<1","N/A","http://selleckchem.com/products/E7080.html","C21H19ClN4O4","free base","N/A","COC1=C(C=C2C(=CC=NC2=C1)OC3=CC(=C(NC(=O)NC4CC4)C=C3)Cl)C(N)=O",2.832,5,3,6]
["S1168","Valproic Acid (NSC 93819) sodium salt","g6","L8000-01","in 10mM DMSO","Autophagy,GABA Receptor,HDAC,Mitophagy,Notch,PGC-1α","Neuronal Signaling","Valproic Acid sodium salt (NSC 93819, Sodium valproate) is a HDAC inhibitor by selectively inducing proteasomal degradation of HDAC2, used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. Valproic acid induces Notch1 signaling in small cell lung cancer (SCLC) cells. Valproic acid is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α.",166.19,"1069-66-5",{"v":33,"d":"33.00"},198.57,{"v":33,"d":"33.00"},198.57,"http://selleckchem.com/products/Sodium-valproate.html","C8H15NaO2","Sodium salt","Sodium valproate,NSC 93819,2-Propylpentanoic Acid","CCCC(CCC)C(=O)O[Na]",1.275,0,0,5]
["S1178","Regorafenib (BAY 73-4506)","h6","L8000-01","in 10mM DMSO","Autophagy,c-Kit,c-RET,PDGFR,Raf,VEGFR","Protein Tyrosine Kinase","Regorafenib (BAY 73-4506,Fluoro-Sorafenib, Resihance, Stivarga) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively. Regorafenib induces autophagy.",482.82,"755037-03-7",{"v":97,"d":"97.00"},{"v":200.9,"d":"200.90"},"<1","N/A","http://selleckchem.com/products/BAY-73-4506.html","C21H15ClF4N4O3","free base","Fluoro-Sorafenib, Resihance, Stivarga,BAY 73-4506","CNC(=O)C1=CC(=CC=N1)OC2=CC(=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2)F",4.381,4,3,6]
["S1185","Ritonavir (ABT-538)","a7","L8000-01","in 10mM DMSO","Apoptosis related,COVID-19,HIV Protease,P450 (e.g. CYP17)","Proteases","Ritonavir (ABT-538, A 84538, RTV, Norvir, Norvir Softgel) is a Cytochrome P450 3A and Protease Inhibitor; Also inhibits Cytochrome P450 2D6, P-Glycoprotein and induces Cytochrome P450 2C19, Cytochrome P450 1A2, Cytochrome P450 2C9, Cytochrome P450 2B6 and UDP Glucuronosyltransferases. Ritonavir induces apoptosis.",720.94,"155213-67-5",{"v":100,"d":"100.00"},138.71,"<1","N/A","http://selleckchem.com/products/Ritonavir.html","C37H48N6O5S2","free base","ABT-538,A 84538, RTV, Norvir, Norvir Softgel","CC(C)C(NC(=O)N(C)CC1=CSC(=N1)C(C)C)C(=O)NC(CC(O)C(CC2=CC=CC=C2)NC(=O)OCC3=CN=CS3)CC4=CC=CC=C4",4.978,6,4,18]
["S1188","Anastrozole (ZD-1033)","b7","L8000-01","in 10mM DMSO","Aromatase","Endocrinology & Hormones","Anastrozole (Arimidex,ZD-1033) is a third-generation nonsteroidal selective aromatase inhibitor. It may offer greater selectivity compared with other aromatase inhibitors, being without any intrinsic endocrine effects and with no apparent effect on the synthesis of adrenal steroids.",293.37,"120511-73-1",{"v":59,"d":"59.00"},201.11,"<1","N/A","http://selleckchem.com/products/Anastrozole.html","C17H19N5","free base","Arimidex,ZD-1033","CC(C)(C#N)C1=CC(=CC(=C1)C[N]2C=NC=N2)C(C)(C)C#N",2.965,2,0,4]
["S1189","Aprepitant (MK-0869)","c7","L8000-01","in 10mM DMSO","CSF-1R,HIV,Interleukins,Neurokinin Receptor,TNF-alpha","Neuronal Signaling","Aprepitant (MK-0869, L-754030, Emend) is a potent and selective neurokinin-1 receptor antagonist with IC50 of 0.1 nM. Aprepitant reduces levels of pro-inflammatory cytokines including G-CSF, IL-6, IL-8 and TNFα. Aprepitant inhibits HIV infection of human macrophages.",534.43,"170729-80-3",{"v":107,"d":"107.00"},200.21,"<1","N/A","http://selleckchem.com/products/Aprepitant.html","C23H21F7N4O3","free base","MK-0869, L-754030, Emend","CC(OC1OCCN(CC2=NNC(=O)N2)C1C3=CC=C(F)C=C3)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F",4.635,4,2,8]
["S1190","Bicalutamide (ICI-176334)","d7","L8000-01","in 10mM DMSO","Androgen Receptor,Autophagy","Endocrinology & Hormones","Bicalutamide (ICI-176334) is an androgen receptor (AR) antagonist with IC50 of 0.16 μM in LNCaP/AR(cs)cell line. Bicalutamide promotes autophagy.",430.37,"90357-06-5",{"v":86,"d":"86.00"},199.83,"<1","N/A","http://selleckchem.com/products/Bicalutamide(Casodex).html","C18H14F4N2O4S","free base","ICI-176334","CC(O)(C[S](=O)(=O)C1=CC=C(F)C=C1)C(=O)NC2=CC=C(C#N)C(=C2)C(F)(F)F",2.926,3,1,6]
["S1191","Fulvestrant (ICI-182780)","e7","L8000-01","in 10mM DMSO","Apoptosis related,Autophagy,Estrogen/progestogen Receptor","Endocrinology & Hormones","Fulvestrant (ICI-182780, ZD 9238, ZM 182780) is an estrogen receptor (ER) antagonist with IC50 of 0.94 nM in a cell-free assay. Fulvestrant also induces autophagy and apoptosis and has antitumor activity.",606.77,"129453-61-8",{"v":100,"d":"100.00"},164.81,"<1","N/A","http://selleckchem.com/products/Fulvestrant.html","C32H47F5O3S","free base","ICI-182780, ZD 9238, ZM 182780","CC12CCC3C(C(CCCCCCCCC[S](=O)CCCC(F)(F)C(F)(F)F)CC4=C3C=CC(=C4)O)C1CCC2O",8.437,1,2,15]
["S1192","Raltitrexed","f7","L8000-01","in 10mM DMSO","DNA/RNA Synthesis,Thymidylate Synthase","DNA Damage/DNA Repair","Raltitrexed (ZD-1694) is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth.",458.49,"112887-68-0",{"v":91,"d":"91.00"},198.48,"<1","N/A","http://selleckchem.com/products/Raltitrexed.html","C21H22N4O6S","free base","ZD-1694, ICI-D1694, D1694","CN(CC1=CC2=C(C=C1)N=C(C)NC2=O)C3=CC=C(S3)C(=O)NC(CCC(O)=O)C(O)=O",1.528,5,2,9]
["S1193","Thalidomide (K17)","g7","L8000-01","in 10mM DMSO","E3 Ligase ,E3 ligase Ligand,TNF-alpha","Ubiquitin","Thalidomide (K17) was introduced as a sedative drug, immunomodulatory agent and also is investigated for treating symptoms of many cancers. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1.",258.23,"50-35-1",{"v":51,"d":"51.00"},{"v":197.5,"d":"197.50"},"<1","N/A","http://selleckchem.com/products/Thalidomide.html","C13H10N2O4","free base","K17","O=C1CCC(N2C(=O)C3=C(C=CC=C3)C2=O)C(=O)N1",0.097,4,1,1]
["S1196","Exemestane (FCE 24304)","h7","L8000-01","in 10mM DMSO","Aromatase","Endocrinology & Hormones","Exemestane (Aromasin,FCE24304, PNU155971,EXE) is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively.",{"v":296.4,"d":"296.40"},"107868-30-4",{"v":54,"d":"54.00"},182.19,"<1","N/A","http://selleckchem.com/products/Exemestane.html","C20H24O2","free base","Aromasin,FCE24304, PNU155971,EXE","CC12CCC3C(CC(=C)C4=CC(=O)C=CC34C)C1CCC2=O",3.606,2,0,0]
["S1197","Finasteride","a8","L8000-01","in 10mM DMSO","5-alpha Reductase","Endocrinology & Hormones","Finasteride (MK-906) is a potent, reversible inhibitor of the rat type 1 5 alpha-reductase with Ki of 10.2 nM, used in the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB).",372.54,"98319-26-7",{"v":75,"d":"75.00"},201.32,"<1","N/A","http://selleckchem.com/products/Finasteride.html","C23H36N2O2","free base","MK-906","CC(C)(C)NC(=O)C1CCC2C3CCC4NC(=O)C=CC4(C)C3CCC12C",3.174,2,2,2]
["S1199","Cladribine (RWJ 26251)","b8","L8000-01","in 10mM DMSO","Adenosine Deaminase,DNA/RNA Synthesis","Neuronal Signaling","Cladribine (RWJ 26251, Leustatin, 2-CdA, 2-chlorodeoxyadenosine, 2-Chloro-2′-deoxyadenosine, CldAdo, Jk 6251, NSC 105014) is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43 μM, 0.75 μM, and 0.18 μM, respectively.",285.69,"4291-63-8",{"v":57,"d":"57.00"},199.52,"<1","N/A","http://selleckchem.com/products/Cladribine.html","C10H12ClN5O3","free base","Leustatin,2-CdA,2-Chloro-2′-deoxyadenosine,CldAdo,Jk 6251,NSC 105014,RWJ 26251","NC1=NC(=NC2=C1N=C[N]2C3CC(O)C(CO)O3)Cl",-0.259,4,3,2]
["S1200","Decitabine (NSC 127716)","c8","L8000-01","in 10mM DMSO","Apoptosis related,DNA Methyltransferase,Nucleoside Analog/Antimetabolite","Epigenetics","Decitabine (Deoxycytidine, Dacogen, 5-aza-2'-deoxycytidine, 5-AZA-dC, 5-aza-CdR,NSC 127716) is a DNA methyltransferase inhibitor, incorporating into DNA and resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. It is used to treat myelodysplastic syndrome (MDS). Decitabine induces cell cycle arrest and apoptosis in various cancer cell lines.",228.21,"2353-33-5",{"v":45,"d":"45.00"},197.19,{"v":10,"d":"10.00"},43.82,"http://selleckchem.com/products/Decitabine.html","C8H12N4O4","free base","Deoxycytidine, Dacogen, 5-aza-2'-deoxycytidine, 5-AZA-dC, 5-aza-CdR,NSC 127716","NC1=NC(=O)N(C=N1)C2CC(O)C(CO)O2",-1.093,4,3,2]
["S1202","Dutasteride","d8","L8000-01","in 10mM DMSO","5-alpha Reductase","Endocrinology & Hormones","Dutasteride (GI198745, GG-745) is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT).",528.53,"164656-23-9",{"v":62,"d":"62.00"},117.31,"<1","N/A","http://selleckchem.com/products/Dutasteride.html","C27H30F6N2O2","free base","GI198745, GG-745","CC12CCC3C(CCC4NC(=O)C=CC34C)C1CCC2C(=O)NC5=CC(=CC=C5C(F)(F)F)C(F)(F)F",5.703,2,2,4]
["S1204","Melatonin (NSC 113928)","e8","L8000-01","in 10mM DMSO","Apoptosis related,ATF/CREB & c-Fos/c-Jun,Autophagy,COX,Mitophagy,MT Receptor","GPCR & G Protein","Melatonin (NSC 113928, NSC 56423, N-Acetyl-5-methoxytryptamine,MT) is a MT receptor agonist, used as a dietary supplement. Melatonin is a selective ATF-6 inhibitor and downregulates COX-2. Melatonin enhances mitophagy and regulates the homeostasis of apoptosis and autophagy.",232.28,"73-31-4",{"v":47,"d":"47.00"},202.34,"<1","N/A","http://selleckchem.com/products/Melatonin.html","C13H16N2O2","free base","NSC 56423, N-Acetyl-5-methoxytryptamine,NSC 113928,MT","COC1=CC2=C([NH]C=C2CCNC(C)=O)C=C1",1.555,2,2,4]
["S1206","Bisoprolol fumarate","f8","L8000-01","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Bisoprolol fumarate (EMD33512) is a selective type β1 adrenergic receptor blocker.",441.52,"104344-23-2",{"v":88,"d":"88.00"},199.31,{"v":88,"d":"88.00"},199.31,"http://selleckchem.com/products/Bisoprolol-Fumarate.html","C22H35NO8","fumarate","EMD33512","CC(C)NCC(O)COC1=CC=C(COCCOC(C)C)C=C1.OC(=O)\\C=C\\C(O)=O",-0.635,5,2,14]
["S1207","Tivozanib (AV-951)","g8","L8000-01","in 10mM DMSO","c-Kit,PDGFR,VEGFR","Protein Tyrosine Kinase","Tivozanib (AV-951, KRN-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 30 nM/6.5 nM/15 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met, EGFR and IGF-1R. Phase 3.",454.86,"475108-18-0",{"v":20,"d":"20.00"},43.97,"<1","N/A","http://selleckchem.com/products/AV-951.html","C22H19ClN4O5","free base","KRN-951","COC1=CC2=C(C=C1OC)C(=CC=N2)OC3=CC=C(NC(=O)NC4=NOC(=C4)C)C(=C3)Cl",4.039,7,2,6]
["S1208","Doxorubicin (Adriamycin) HCl","h8","L8000-01","in 10mM DMSO","ADC Cytotoxin,AMPK,Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,HIV,Mitophagy,Topoisomerase","DNA Damage/DNA Repair","Doxorubicin (Adriamycin, NSC 123127, DOX, Hydroxydaunorubicin) HCl is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage, mitophagy and apoptosis in tumor cells. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.",579.98,"25316-40-9",{"v":100,"d":"100.00"},172.42,{"v":20,"d":"20.00"},34.48,"http://selleckchem.com/products/Adriamycin.html","C27H29NO11.HCl","Hydrochloride","NSC 123127, DOX, Doxorubicin hydrochloride, Hydroxydaunorubicin HCl,Adriamycin HCl","Cl.COC1=C2C(=O)C3=C(C(=C4CC(O)(CC(OC5CC(N)C(O)C(C)O5)C4=C3O)C(=O)CO)O)C(=O)C2=CC=C1",0.338,6,5,5]
["S1209","Fluorouracil (5-Fluorouracil, 5-FU)","a9","L8000-01","in 10mM DMSO","Apoptosis related,DNA/RNA Synthesis,HIV,Nucleoside Analog/Antimetabolite,Thymidylate Synthase","DNA Damage/DNA Repair","Fluorouracil (5-Fluorouracil, 5-FU, NSC 19893) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV.",130.08,"51-21-8",{"v":26,"d":"26.00"},199.88,"<1","N/A","http://selleckchem.com/products/Adrucil(Fluorouracil).html","C4H3FN2O2","free base","NSC 19893,5-Fluorouracil, 5-FU","FC1=CNC(=O)NC1=O",-1.102,2,2,0]
["S1210","Methotrexate (CL-14377)","b9","L8000-01","in 10mM DMSO","ADC Cytotoxin,DHFR","Metabolism","Methotrexate (CL14377, MTX, NCI-C04671, Amethopterin, WR19039, abitrexate), analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH. Methotrexate (MTX) induces apoptosis.",454.44,"59-05-2",{"v":90,"d":"90.00"},198.05,"<1","N/A","http://selleckchem.com/products/Abitrexate.html","C20H22N8O5","free base","NCI-C04671, Amethopterin, CL14377, WR19039, abitrexate","CN(CC1=NC2=C(N)N=C(N)N=C2N=C1)C3=CC=C(C=C3)C(=O)NC(CCC(O)=O)C(O)=O",0.114,7,3,9]
["S1212","Bendamustine (SDX105) HCl","c9","L8000-01","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Bendamustine (SDX-105, Cytostasane) HCl is a DNA-damaging agent with IC50 of 50 μM in cell-free assay.",394.72,"3543-75-7",{"v":78,"d":"78.00"},197.61,{"v":2,"d":"2.00"},5.07,"http://selleckchem.com/products/Bendamustine-Hydrochloride.html","C16H21Cl2N3O2.HCl","Hydrochloride","Cytostasane HCl","Cl.C[N]1C(=NC2=CC(=CC=C12)N(CCCl)CCCl)CCCC(O)=O",3.988,2,0,9]
["S1213","Nelarabine","d9","L8000-01","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Nelarabine (506U78,Arranon) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.",297.27,"121032-29-9",{"v":60,"d":"60.00"},201.84,{"v":3,"d":"3.00"},10.09,"http://selleckchem.com/products/Arranon.html","C11H15N5O5","free base","506U78,Arranon","COC1=NC(=NC2=C1N=C[N]2C3OC(CO)C(O)C3O)N",-1.376,5,4,3]
["S1214","Bleomycin (NSC125066) sulfate","e9","L8000-01","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,DNA/RNA Synthesis,Selection Antibiotics for Transfected Cell","DNA Damage/DNA Repair","Bleomycin Sulfate (Blenoxane,NSC125066) is a glycopeptide antibiotic and an anticancer agent for squamous cell carcinomas (SCC) with IC50 of 4 nM in UT-SCC-19A cells.",1512.62,"9041-93-4",{"v":100,"d":"100.00"},{"v":66,"d":"66.00"},"N/A","N/A","http://www.selleckchem.com/products/Bleomycin-sulfate.html","C55H85N17O25S4","Sulfate","Blenoxane,NSC125066","CC(O)C(NC(=O)C(C)C(O)C(C)NC(=O)C(NC(=O)C1=C(C)C(=NC(=N1)C(CC(N)=O)NCC(N)C(N)=O)N)C(OC2OC(CO)C(O)C(O)C2OC3OC(CO)C(O)C(OC(N)=O)C3O)C4=C[NH]C=N4)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C.O[S]([O-])(=O)=O","N/A","N/A","N/A","N/A"]
["S1218","Clofarabine","f9","L8000-01","in 10mM DMSO","Apoptosis related,Autophagy,DNA/RNA Synthesis,RNR","DNA Damage/DNA Repair","Clofarabine (Clolar) inhibits the enzymatic activities of ribonucleotide reductase (RNR) (IC50 = 65 nM) and DNA polymerase. Clofarabine induces autophagy and apoptosis.",303.68,"123318-82-1",{"v":60,"d":"60.00"},197.58,"<1","N/A","http://selleckchem.com/products/Clofarabine.html","C10H11ClFN5O3","free base","Clolar","NC1=C2N=C[N](C3OC(CO)C(O)C3F)C2=NC(=N1)Cl",-0.085,4,3,2]
["S1221","Dacarbazine (NSC-45388)","g9","L8000-01","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,DNA/RNA Synthesis","DNA Damage/DNA Repair","Dacarbazine (NSC-45388, DTIC-Dome, Imidazole Carboxamide) is a triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis; used in the treatment of various cancers.",182.18,"4342-03-4",{"v":12,"d":"12.00"},65.87,{"v":2,"d":"2.00"},10.98,"http://selleckchem.com/products/Dacarbazine.html","C6H10N6O","free base","DTIC-Dome, Imidazole Carboxamide,NSC-45388","CN(C)N=NC1=C(N=C[NH]1)C(N)=O",-0.344,4,2,3]
["S1222","Dexrazoxane HCl (ICRF-187)","h9","L8000-01","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Dexrazoxane HCl (ADR-529,Totect, ICRF-187, Zinecard, Cardioxane) is an intracellular iron chelator, which decreases the formation of superoxide radicals, used as a cardioprotective agent; also an inhibitor of topoisomerase II",304.73,"149003-01-0",{"v":60,"d":"60.00"},{"v":196.9,"d":"196.90"},{"v":60,"d":"60.00"},{"v":196.9,"d":"196.90"},"http://selleckchem.com/products/Dexrazoxane-Hydrochloride.html","C11H16N4O4.HCl","Hydrochloride","ADR-529,Totect, ICRF-187, Zinecard, Cardioxane","Cl.CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2",-1.722,4,2,3]
["S1223","Epirubicin (IMI 28) HCl","a10","L8000-01","in 10mM DMSO","Apoptosis related,Topoisomerase","DNA Damage/DNA Repair","Epirubicin HCl (Ellence, Pharmorubicin, Epirubicin Ebewe,IMI 28, NSC 256942, 4'-epidoxorubicin,Epirubicin hydrochloride), a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. Epirubicin induces apoptosis.",579.98,"56390-09-1",{"v":100,"d":"100.00"},172.42,{"v":100,"d":"100.00"},172.42,"http://selleckchem.com/products/Ellence.html","C27H29NO11.HCl","Hydrochloride","Ellence, Pharmorubicin, Epirubicin Ebewe,IMI 28, NSC 256942, 4'-epidoxorubicin,Epirubicin hydrochloride","Cl.COC1=C2C(=O)C3=C(C(=C4CC(O)(CC(OC5CC(N)C(O)C(C)O5)C4=C3O)C(=O)CO)O)C(=O)C2=CC=C1",0.338,6,5,5]
["S1225","Etoposide (VP-16)","b10","L8000-01","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,Autophagy,Mitophagy,Topoisomerase","DNA Damage/DNA Repair","Etoposide (VP-16213,Vepesid,VP-16) is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II  inhibition activity. Etoposide induces autophagy, mitophagy and apoptosis.",588.56,"33419-42-0",{"v":100,"d":"100.00"},169.91,"<1","N/A","http://selleckchem.com/products/Etopophos.html","C29H32O13","free base","VP-16213,Vepesid,VP-16","COC1=CC(=CC(=C1O)OC)C2C3C(COC3=O)C(OC4OC5COC(C)OC5C(O)C4O)C6=C2C=C7OCOC7=C6",0.935,10,3,5]
["S1227","Raloxifene HCl","c10","L8000-01","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Raloxifene (LY156758, Keoxifene) HCl is a selective and orally active estrogen receptor modulator (SERM), which inhibits human cytosolic aldehyde oxidase-catalyzed phthalazine oxidation activity with IC50 of 5.7 nM.",510.04,"82640-04-8",{"v":100,"d":"100.00"},196.06,"<1","N/A","http://selleckchem.com/products/Evista.html","C28H27NO4S.HCl","Hydrochloride","LY156758 (Keoxifene) HCl","Cl.OC1=CC=C(C=C1)C2=C(C(=O)C3=CC=C(OCCN4CCCCC4)C=C3)C5=C(S2)C=C(O)C=C5",6.843,2,2,7]
["S1229","Fludarabine Phosphate","d10","L8000-01","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Fludarabine Phosphate (F-ara-A, NSC 312887) is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis.",365.21,"75607-67-9",{"v":73,"d":"73.00"},199.88,{"v":2,"d":"2.00"},5.48,"http://selleckchem.com/products/Fludara.html","C10H13FN5O7P","Phosphate","F-ara-A (NSC 312887) Phosphate","NC1=NC(=NC2=C1N=C[N]2C3OC(CO[P](O)(O)=O)C(O)C3O)F",-1.384,5,3,4]
["S1231","Topotecan (NSC609699) HCl","e10","L8000-01","in 10mM DMSO","Apoptosis related,Autophagy,Topoisomerase","DNA Damage/DNA Repair","Topotecan HCl (Nogitecan HCl, SKFS 104864A,Hycamtin, NSC 609699) is a topoisomerase I inhibitor for MCF-7 Luc cells and DU-145 Luc cells with IC50 of 13 nM and 2 nM in cell-free assays, respectively. Topotecan HCl induces autophagy and apoptosis.",457.91,"119413-54-6",{"v":91,"d":"91.00"},198.73,{"v":91,"d":"91.00"},198.73,"http://selleckchem.com/products/Topotecan-Hydrochloride.html","C23H23N3O5.HCl","Hydrochloride","Nogitecan HCl, SKFS 104864A,Hycamtin, NSC 609699","Cl.CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC(=C(CN(C)C)C5=C4)O)C2=O",1.959,4,1,3]
["S1233","2-Methoxyestradiol (2-MeOE2)","f10","L8000-01","in 10mM DMSO","Apoptosis related,Autophagy,HIF,Microtubule Associated","Angiogenesis","2-Methoxyestradiol (2-MeOE2, NSC 659853, 2-ME2) depolymerizes microtubules and blocks HIF-1α nuclear accumulation and HIF-transcriptional activity. 2-Methoxyestradiol induces both autophagy and apoptosis in various carcinogenic cell lines.",302.41,"362-07-2",{"v":60,"d":"60.00"},198.41,"<1","N/A","http://selleckchem.com/products/2-Methoxyestradiol(2ME2).html","C19H26O3","free base","NSC 659853, 2-ME2","COC1=C(O)C=C2CCC3C(CCC4(C)C(O)CCC34)C2=C1",3.821,1,2,1]
["S1235","Letrozole (CGS 20267)","g10","L8000-01","in 10mM DMSO","Aromatase,Autophagy","Endocrinology & Hormones","Letrozole (CGS 20267,Femara, Piroxicam) is a third generation inhibitor of aromatase with IC50 of 0.07-20 nM in cell-free assays.It has no effect on the plasma levels of 17α-OH progesterone, thyroid-stimulating hormone (TSH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), or androstenedione and does not affect normal urine electrolyte excretion or thyroid function in clinical studies. Letrozole induces autophagy.",{"v":285.3,"d":"285.30"},"112809-51-5",{"v":57,"d":"57.00"},199.79,"<1","N/A","http://selleckchem.com/products/Letrozole.html","C17H11N5","free base","CGS 20267,Femara, Piroxicam","N#CC1=CC=C(C=C1)C([N]2C=NC=N2)C3=CC=C(C=C3)C#N",2.749,2,0,3]
["S1237","Temozolomide (CCRG 81045)","h10","L8000-01","in 10mM DMSO","Apoptosis related,Autophagy,DNA/RNA Synthesis","DNA Damage/DNA Repair","Temozolomide (NSC 362856,TMZ,CCRG 81045,Methazolastone,Temodar,Temodal) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosis and exhibits antitumor activity.",194.15,"85622-93-1",{"v":38,"d":"38.00"},195.72,"<1","N/A","http://selleckchem.com/products/Methazolastone.html","C6H6N6O2","free base","NSC 362856,TMZ,CCRG 81045,Methazolastone,Temodar,Temodal","CN1N=NC2=C(N=C[N]2C1=O)C(N)=O",0.052,5,1,1]
["S1238","Tamoxifen (ICI 46474)","a11","L8000-01","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,ATPase,Autophagy,Estrogen/progestogen Receptor,HSP (HSP90)","Angiogenesis","Tamoxifen (ICI 46474, (Z)-Tamoxifen, trans-Tamoxifen) is a selective estrogen receptor modulator (SERM). Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen induces apoptosis.",371.51,"10540-29-1",{"v":74,"d":"74.00"},199.19,"<1","N/A","http://selleckchem.com/products/Nolvadex.html","C26H29NO","Free Base","ICI 46474, (Z)-Tamoxifen, trans-Tamoxifen","CC/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(OCCN(C)C)C=C3.OC(=O)CC(O)(CC(O)=O)C(O)=O",1.966,4,0,13]
["S1241","Vincristine (NSC-67574) sulfate","b11","L8000-01","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,Autophagy,Microtubule Associated","Cytoskeletal Signaling","Vincristine sulfate (NSC-67574, Leurocristine, Oncovin, 22-Oxovincaleukoblastine) is an inhibitor of polymerization of microtubules by binding to tubulin with IC50 of 32 μM in a cell-free assay. Vincristine sulfate induces apoptosis.",923.04,"2068-78-2",{"v":100,"d":"100.00"},108.34,{"v":60,"d":"60.00"},{"v":65,"d":"65.00"},"http://selleckchem.com/products/Vincristine-Sulfate.html","C46H58N4O14S","free base","Leurocristine, Oncovin, NSC-67574, 22-Oxovincaleukoblastine","CCC1(O)CC2CN(CCC3=C([NH]C4=C3C=CC=C4)C(C2)(C(=O)OC)C5=CC6=C(C=C5OC)N(C=O)C7C(O)(C(OC(C)=O)C8(CC)C=CCN9CCC67C89)C(=O)OC)C1.O[S](O)(=O)=O",3.365,8,1,10]
["S1243","Agomelatine (S20098)","c11","L8000-01","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Agomelatine (Valdoxan, Melitor, Thymanax,S20098) is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.",{"v":243.3,"d":"243.30"},"138112-76-2",{"v":48,"d":"48.00"},197.29,"<1","N/A","http://selleckchem.com/products/Agomelatine.html","C15H17NO2","free base","Valdoxan, Melitor, Thymanax,S20098","COC1=CC2=C(CCNC(C)=O)C=CC=C2C=C1",{"v":2.17,"d":"2.170"},2,1,4]
["S1245","Latrepirdine 2HCl","d11","L8000-01","in 10mM DMSO","5-HT Receptor,GluR,Histamine Receptor","Neuronal Signaling","Latrepirdine is an orally active,and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihistamine drug.",392.37,"97657-92-6",{"v":24,"d":"24.00"},61.17,"<1","N/A","http://selleckchem.com/products/Dimebon.html","C21H25N3.2HCl","Dihydrochloride","N/A","Cl.Cl.CN1CCC2=C(C1)C3=C(C=CC(=C3)C)[N]2CCC4=CC=C(C)N=C4",4.769,1,0,3]
["S1247","Leflunomide (HWA486)","e11","L8000-01","in 10mM DMSO","AhR,Dehydrogenase","Metabolism","Leflunomide (HWA486, RS-34821, SU101, Arava) is a pyrimidine synthesis and protein tyrosine kinase inhibitor belonging to the DMARD, used as an immunosuppressant agent. The active metabolite of Leflunomide is A77 1726, which inhibits dihydroorotate dehydrogenase (DHODH). Leflunomide is also an agonist of the AhR.",270.21,"75706-12-6",{"v":54,"d":"54.00"},199.84,"<1","N/A","http://selleckchem.com/products/Leflunomide.html","C12H9F3N2O2","free base","HWA486, RS-34821, SU101, Arava","CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F",2.156,3,1,3]
["S1250","Enzalutamide (MDV3100)","f11","L8000-01","in 10mM DMSO","Androgen Receptor,Autophagy","Endocrinology & Hormones","Enzalutamide (MDV3100) is an androgen-receptor (AR) antagonist with IC50 of 36 nM in LNCaP cells. Enzalutamide is shown to increase autophagy.",464.44,"915087-33-1",{"v":92,"d":"92.00"},198.09,"<1","N/A","http://selleckchem.com/products/MDV3100.html","C21H16F4N4O2S","free base","MDV3100","CNC(=O)C1=C(F)C=C(C=C1)N2C(=S)N(C(=O)C2(C)C)C3=CC=C(C#N)C(=C3)C(F)(F)F",4.954,2,1,4]
["S1251","Dienogest","g11","L8000-01","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Dienogest (STS 557) is an orally active synthetic progesterone, used for contraception and the treatment of endometriosis.",311.42,"65928-58-7",{"v":62,"d":"62.00"},199.09,"<1","N/A","http://selleckchem.com/products/Dienogest.html","C20H25NO2","free base","STS 557","CC12CCC3=C4CCC(=O)C=C4CCC3C1CCC2(O)CC#N",3.046,1,0,1]
["S1255","Nepafenac","h11","L8000-01","in 10mM DMSO","COX","Neuronal Signaling","Nepafenac (AHR 9434, AL 6515) is a prodrug of amfenac that acts as an inhibitor of COX-1 and COX-2 activity, used in the treatment of pain and inflammation associated with cataract surgery.",254.28,"78281-72-8",{"v":50,"d":"50.00"},196.63,"<1","N/A","http://selleckchem.com/products/Nepafenac.html","C15H14N2O2","free base","AHR 9434, AL 6515","NC(=O)CC1=CC=CC(=C1N)C(=O)C2=CC=CC=C2",1.524,2,2,4]
["S1257","Posaconazole (SCH 56592)","a2","L8000-02","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Posaconazole (SCH 56592,POS,Noxafil) is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14ɑ demethylase inhibitor with IC50 of 0.25 μM. Posaconazole has a median terminal elimination half-life of 15-35 hours.",700.78,"171228-49-2",{"v":100,"d":"100.00"},{"v":142.7,"d":"142.70"},"<1","N/A","http://selleckchem.com/products/Posaconazole.html","C37H42F2N8O4","free base","SCH 56592,POS,Noxafil","CCC(C(C)O)N1N=CN(C1=O)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(OCC5COC(C5)(C[N]6C=NC=N6)C7=CC=C(F)C=C7F)C=C4",5.096,6,1,12]
["S1259","Ramelteon","b2","L8000-02","in 10mM DMSO","MT Receptor","GPCR & G Protein","Ramelteon (TAK-375) is a novel melatonin receptor agonist for human MT1 and MT2 receptors and chick forebrain melatonin receptors with Ki of 14 pM, 112 pM and 23.1 pM, respectively.",259.34,"196597-26-9",{"v":52,"d":"52.00"},200.51,"<1","N/A","http://selleckchem.com/products/Ramelteon.html","C16H21NO2","free base","TAK-375","CCC(=O)NCCC1CCC2=CC=C3OCCC3=C12",2.826,2,1,4]
["S1260","Cinacalcet (AMG-073) HCl","c2","L8000-02","in 10mM DMSO","CaSR","GPCR & G Protein","Cinacalcet (Mimpara, Sensipar,AMG-073) HCl represents a new class of compounds for the treatment of hyperparathyroidism.",393.87,"364782-34-3",{"v":79,"d":"79.00"},200.57,"<1","N/A","http://selleckchem.com/products/Cinacalcet-hydrochloride.html","C22H22F3N.HCl","Hydrochloride","Mimpara, Sensipar,AMG-073","Cl.CC(NCCCC1=CC(=CC=C1)C(F)(F)F)C2=CC=CC3=C2C=CC=C3",6.338,0,1,7]
["S1261","Celecoxib (SC 58635)","d2","L8000-02","in 10mM DMSO","COX","Neuronal Signaling","Celecoxib (Celebrex, Celebra,SC 58635) is a selective COX-2 inhibitor with IC50 of 40 nM in Sf9 cells.",381.37,"169590-42-5",{"v":76,"d":"76.00"},199.28,"<1","N/A","http://selleckchem.com/products/Celecoxib.html","C17H14F3N3O2S","free base","Celebrex, Celebra,SC 58635","CC1=CC=C(C=C1)C2=CC(=N[N]2C3=CC=C(C=C3)[S](N)(=O)=O)C(F)(F)F",4.428,3,1,4]
["S1267","Vemurafenib (PLX4032)","e2","L8000-02","in 10mM DMSO","Autophagy,Raf","MAPK","Vemurafenib (PLX4032, RG7204, RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay. 10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold. Vemurafenib (PLX4032, RG7204) induces autophagy.",489.92,"918504-65-1",{"v":97,"d":"97.00"},197.99,"<1","N/A","http://selleckchem.com/products/PLX-4032.html","C23H18ClF2N3O3S","free base","RG7204, RO5185426,PLX4032","CCC[S](=O)(=O)NC1=CC=C(F)C(=C1F)C(=O)C2=C[NH]C3=NC=C(C=C23)C4=CC=C(Cl)C=C4",4.953,4,2,7]
["S1271","Acarbose","f2","L8000-02","in 10mM DMSO","Carbohydrate Metabolism","Metabolism","Acarbose(BAY g 5421,Prandase, Precose, Glucobay, Bay-g 5421) is an inhibitor of intestinal alpha-glucosidase, used to treat type 2 diabetes mellitus.",{"v":645.6,"d":"645.60"},"56180-94-0",{"v":100,"d":"100.00"},154.89,{"v":100,"d":"100.00"},154.89,"http://selleckchem.com/products/Acarbose.html","C25H43NO18","free base","BAY g 5421,Prandase, Precose, Glucobay, Bay-g 5421","CC1OC(OC2C(O)C(O)C(OC2CO)OC3C(O)C(O)C(O)OC3CO)C(O)C(O)C1NC4C=C(CO)C(O)C(O)C4O",-6.839,5,13,9]
["S1276","Adapalene","g2","L8000-02","in 10mM DMSO","Retinoid Receptor","Metabolism","Adapalene (CD-271) is a dual RAR and RXR agonist, used in the treatment of acne.",412.52,"106685-40-9",{"v":8,"d":"8.00"},19.39,"<1","N/A","http://selleckchem.com/products/Adapalene.html","C28H28O3","free base","CD-271","COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(O)=O)[C]45CC6[CH2][CH](C[CH]([CH2]6)C4)C5",6.279,2,0,4]
["S1278","Altretamine","h2","L8000-02","in 10mM DMSO","DNA alkylator","DNA Damage/DNA Repair","Altretamine (Hexamethylmelamine, NSC13875, ENT50852) is an anti-neoplastic agent.",210.28,"645-05-6",{"v":15,"d":"15.00"},71.33,"<1","N/A","http://selleckchem.com/products/Altretamine.html","C9H18N6","free base","Hexamethylmelamine, NSC13875, ENT50852","CN(C)C1=NC(=NC(=N1)N(C)C)N(C)C",1.995,3,0,3]
["S1280","Amisulpride","a3","L8000-02","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Amisulpride (DAN-2163) is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.",369.48,"71675-85-9",{"v":73,"d":"73.00"},197.57,"<1","N/A","http://selleckchem.com/products/Amisulpride.html","C17H27N3O4S","free base","DAN-2163","CCN1CCCC1CNC(=O)C2=CC(=C(N)C=C2OC)[S](=O)(=O)CC",1.127,4,2,7]
["S1281","Aniracetam","b3","L8000-02","in 10mM DMSO","AMPA Receptor-kainate Receptor-NMDA Receptor","Neuronal Signaling","Aniracetam (RO 13-5057) is a nootropics and neuroprotective drug.",219.24,"72432-10-1",{"v":44,"d":"44.00"},200.69,"<1","N/A","http://selleckchem.com/products/Aniracetam.html","C12H13NO3","free base","RO 13-5057","COC1=CC=C(C=C1)C(=O)N2CCCC2=O",1.267,3,0,2]
["S1282","Artemisinin","c3","L8000-02","in 10mM DMSO","ADC Cytotoxin,Anti-infection","Microbiology","Artemisinin (Qinghaosu,Artemisinine,Coartem,NSC 369397) is a sesquiterpene endoperoxide which is a potent antimalarial agent.",282.33,"63968-64-9",{"v":57,"d":"57.00"},201.89,"<1","N/A","http://selleckchem.com/products/Artemisinin.html","C15H22O5","free base","Qinghaosu,Artemisinine,Coartem,NSC 369397","CC1CCC2C(C)C(=O)OC3OC4(C)CCC1C23OO4",1.998,5,0,0]
["S1283","Asenapine maleate","d3","L8000-02","in 10mM DMSO","5-HT Receptor,Adrenergic Receptor","Neuronal Signaling","Asenapine maleate (Org 5222) is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder.",401.84,"85650-56-2",{"v":80,"d":"80.00"},199.08,"<1","N/A","http://selleckchem.com/products/Asenapine.html","C17H16ClNO.C4H4O4","Maleate","Org 5222","CN1CC2C(C1)C3=C(OC4=C2C=CC=C4)C=CC(=C3)Cl.OC(=O)\\C=C/C(O)=O",0.883,3,0,2]
["S1284","Benazepril HCl","e3","L8000-02","in 10mM DMSO","RAAS","Endocrinology & Hormones","Benazepril HCl (CGS 14824A) is a novel angiotensin I converting enzyme inhibitor, used primarily in treatment of hypertension.",460.95,"86541-74-4",{"v":92,"d":"92.00"},199.59,{"v":19,"d":"19.00"},41.22,"http://selleckchem.com/products/Benazepril-hydrochloride.html","C24H28N2O5.HCl","Hydrochloride","CGS 14824A HCl","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC2CCC3=C(C=CC=C3)N(CC(O)=O)C2=O",1.003,4,1,10]
["S1287","Bumetanide","f3","L8000-02","in 10mM DMSO","NKCC","Transmembrane Transporters","Bumetanide (Bumex) is a loop diuretic of the sulfamyl category to treat heart failure. Bumetanide is a selective Na+-K+-Cl- cotransporter 1 (NKCC1) inhibitor, weakly inhibits NKCC2, with IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively.",364.42,"28395-03-1",{"v":73,"d":"73.00"},200.32,"<1","N/A","http://selleckchem.com/products/Bumetanide.html","C17H20N2O5S","free base","N/A","CCCCNC1=C(OC2=CC=CC=C2)C(=CC(=C1)C(O)=O)[S](N)(=O)=O",2.862,4,2,8]
["S1289","Carmofur","g3","L8000-02","in 10mM DMSO","COVID-19,DNA/RNA Synthesis","DNA Damage/DNA Repair","Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.",257.26,"61422-45-5",{"v":52,"d":"52.00"},202.13,"<1","N/A","http://selleckchem.com/products/Carmofur.html","C11H16FN3O3","free base","HCFU","CCCCCCNC(=O)N1C=C(F)C(=O)NC1=O",1.125,3,2,5]
["S1291","Cetirizine DiHCl","h3","L8000-02","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Cetirizine DiHCl (Zyrtec, Reactine,UCB P071) is an antihistamine.",461.81,"83881-52-1",{"v":92,"d":"92.00"},199.22,{"v":92,"d":"92.00"},199.22,"http://selleckchem.com/products/Cetirizine-Dihydrochloride.html","C21H25ClN2O3.2HCl","Dihydrochloride","Zyrtec, Reactine,UCB P071","Cl.Cl.OC(=O)COCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3",1.217,2,0,8]
["S1294","Cilostazol (OPC-13013)","a4","L8000-02","in 10mM DMSO","PDE","Metabolism","Cilostazol (Pletal,OPC-13013) is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 μM and inhibitor of adenosine uptake.",369.46,"73963-72-1",{"v":74,"d":"74.00"},200.29,"<1","N/A","http://selleckchem.com/products/Cilostazol.html","C20H27N5O2","free base","Pletal,OPC-13013","O=C1CCC2=C(N1)C=CC(=C2)OCCCCC3=NN=N[N]3C4CCCCC4",{"v":3.23,"d":"3.230"},5,1,7]
["S1299","Floxuridine (NSC 27640)","b4","L8000-02","in 10mM DMSO","Apoptosis related,CMV,DNA/RNA Synthesis","DNA Damage/DNA Repair","Floxuridine (NSC 27640, Deoxyfluorouridine, FUDR) is a prodrug that is rapidly catabolized to 5-fluorouracil in vivo. Floxuridine is used to treat various cancers, particularly metastases to the liver. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage and apoptosis. Floxuridine has antiviral effects against HSV and CMV.",246.19,"50-91-9",{"v":49,"d":"49.00"},199.03,{"v":49,"d":"49.00"},199.03,"http://selleckchem.com/products/Floxuridine.html","C9H11FN2O5","free base","Deoxyfluorouridine, FUDR,NSC 27640","OCC1OC(CC1O)N2C=C(F)C(=O)NC2=O",-1.775,3,3,2]
["S1300","Tegafur (FT-207)","c4","L8000-02","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Tegafur (NSC 148958,Fluorafur,FT-207) is a substance being used in the treatment of some types of cancer.",200.17,"17902-23-7",{"v":40,"d":"40.00"},199.83,{"v":8,"d":"8.00"},39.97,"http://selleckchem.com/products/Ftorafur.html","C8H9FN2O3","free base","NSC 148958,Fluorafur,FT-207","FC1=CN(C2CCCO2)C(=O)NC1=O",-0.625,3,1,1]
["S1302","Ifosfamide (NSC109724)","d4","L8000-02","in 10mM DMSO","DNA alkylator,DNA/RNA Synthesis","DNA Damage/DNA Repair","Ifosfamide (Mitoxana, Ifex,Isophosphamide,NSC109724) is a nitrogen mustard alkylating agent used in the treatment of cancer.",261.09,"3778-73-2",{"v":52,"d":"52.00"},199.17,{"v":52,"d":"52.00"},199.17,"http://selleckchem.com/products/Ifosfamide.html","C7H15Cl2N2O2P","free base","Mitoxana, Ifex,Isophosphamide,NSC109724","ClCCN[P]1(=O)OCCCN1CCCl",0.144,2,1,5]
["S1304","Megestrol Acetate","e4","L8000-02","in 10mM DMSO","Androgen Receptor,Estrogen/progestogen Receptor","Endocrinology & Hormones","Megestrol acetate (BDH1298, SC10363) is a synthetic progestogen, used to treat breast cancer and loss of appetite.",384.51,"595-33-5",{"v":33,"d":"33.00"},85.82,"<1","N/A","http://selleckchem.com/products/Megestrol-Acetate.html","C24H32O4","free base","BDH1298, SC10363","CC(=O)OC1(CCC2C3C=C(C)C4=CC(=O)CCC4(C)C3CCC12C)C(C)=O",3.505,4,0,3]
["S1305","Mercaptopurine (6-MP)","f4","L8000-02","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Mercaptopurine(6-MP) is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.",152.18,"50-44-2",{"v":30,"d":"30.00"},197.13,"<1","N/A","http://selleckchem.com/products/Mercaptopurine.html","C5H4N4S","free base","6-MP","S=C1N=CNC2=C1[NH]C=N2",0.367,2,2,0]
["S1319","Costunolide","h4","L8000-02","in 10mM DMSO","Telomerase","DNA Damage/DNA Repair","Costunolide (NSC 106404), a natural sesquiterpene compound with multiple biological activities; inhibits FPTase with IC50 of 20 μM, also inhibits telomerase with IC50 of 65-90 μM.",232.32,"553-21-9",{"v":47,"d":"47.00"},202.31,"<1","N/A","http://selleckchem.com/products/Costunolide.html","C15H20O2","free base","NSC 106404","CC/1=C\\CC\\C(=C\\C2OC(=O)C(=C)C2CC1)C",4.022,2,0,0]
["S1322","Dexamethasone (MK-125)","a5","L8000-02","in 10mM DMSO","Autophagy,Complement System,COVID-19,Glucocorticoid Receptor,IL Receptor,Mitophagy","Immunology & Inflammation","Dexamethasone (MK-125, NSC 34521, Hexadecadrol, Prednisolone F) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects. Dexamethasone induces autophagy and mitophagy. Dexamethasone is tested in hospitalized patients with COVID-19 and is found to have benefits for critically ill patients.",392.46,"50-02-2",{"v":79,"d":"79.00"},201.29,"<1","N/A","http://selleckchem.com/products/Dexamethasone.html","C22H29FO5","free base","NSC 34521, Hexadecadrol, Prednisolone F,MK-125","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO",1.708,2,2,2]
["S1324","Doxazosin Mesylate","b5","L8000-02","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Doxazosin, a quinazoline-derivative, selectively antagonizes postsynaptic α1-adrenergic receptors, used in the treatment of high blood pressure and urinary retention associated with benign prostatic hyperplasia.",547.58,"77883-43-3",{"v":15,"d":"15.00"},27.39,"<1","N/A","http://selleckchem.com/products/Doxazosin-mesylate.html","C23H25N5O5.CH4O3S","Mesylate","N/A","COC1=C(OC)C=C2C(=NC(=NC2=C1)N3CCN(CC3)C(=O)C4COC5=C(O4)C=CC=C5)N.C[S](O)(=O)=O",2.071,7,1,4]
["S1326","Edaravone","c5","L8000-02","in 10mM DMSO","Antioxidant","ER stress & UPR","Edaravone (MCI-186) is a novel potent free radical scavenger that has been clinically used to reduce the neuronal damage following ischemic stroke.",{"v":174.2,"d":"174.20"},"89-25-8",{"v":35,"d":"35.00"},200.92,"<1","N/A","http://selleckchem.com/products/Edaravone.html","C10H10N2O","free base","MCI-186","CC1=NN(C(=O)C1)C2=CC=CC=C2",1.123,2,0,1]
["S1328","Etodolac","d5","L8000-02","in 10mM DMSO","COX","Neuronal Signaling","Etodolac(AY-24236) is a nonsteroidal anti-inflammatory drug (NSAID) and a COX inhibitor, used for the treatment of inflammation and pain.",287.35,"41340-25-4",{"v":58,"d":"58.00"},201.84,"<1","N/A","http://selleckchem.com/products/Etodolac.html","C17H21NO3","free base","AY-24236","CCC1=CC=CC2=C1[NH]C3=C2CCOC3(CC)CC(O)=O",3.723,2,1,4]
["S1330","Felbamate","f5","L8000-02","in 10mM DMSO","NMDAR","Neuronal Signaling","Felbamate (Felbatol, ADD-03055,W-554) is an anticonvulsant drug used in the treatment of epilepsy; NMDAR antagonist.",238.24,"25451-15-4",{"v":48,"d":"48.00"},201.48,"<1","N/A","http://selleckchem.com/products/Felbamate.html","C11H14N2O4","free base","Felbatol, ADD-03055,W-554","NC(=O)OCC(COC(N)=O)C1=CC=CC=C1",0.984,4,2,7]
["S1331","Fluconazole (UK 49858)","g5","L8000-02","in 10mM DMSO","Fungal,P450 (e.g. CYP17)","Metabolism","Fluconazole (Diflucan, Trican, Alfumet,UK 49858) is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol,used in the treatment and prevention of superficial and systemic fungal infections.",306.27,"86386-73-4",{"v":61,"d":"61.00"},199.17,"<1","N/A","http://selleckchem.com/products/Fluconazole.html","C13H12F2N6O","free base","Diflucan, Trican, Alfumet,UK 49858","OC(C[N]1C=NC=N1)(C[N]2C=NC=N2)C3=C(F)C=C(F)C=C3",{"v":0.75,"d":"0.750"},4,0,5]
["S1332","Flumazenil (RO 15-1788)","h5","L8000-02","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Flumazenil (RO 15-1788) is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses.",303.29,"78755-81-4",{"v":5,"d":"5.00"},16.49,"<1","N/A","http://selleckchem.com/products/Flumazenil.html","C15H14FN3O3","free base","RO 15-1788","CCOC(=O)C1=C2CN(C)C(=O)C3=CC(=CC=C3[N]2C=N1)F",1.583,4,0,3]
["S1333","Fluoxetine (Lilly 110140) HCl","a6","L8000-02","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Fluoxetine HCl (Prozac, Sarafem,LY-110140) is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, used in the treatment of depression.",345.79,"56296-78-7",{"v":69,"d":"69.00"},199.54,{"v":4,"d":"4.00"},11.57,"http://selleckchem.com/products/Fluoxetine-hydrochloride.html","C17H18F3NO.HCl","Hydrochloride","Prozac, Sarafem,LY-110140","Cl.CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C2=CC=CC=C2",4.415,1,1,7]
["S1334","Flupirtine maleate","b6","L8000-02","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Flupirtine maleate is the salt form of Flupirtine, which is a centrally acting non-opioid analgesia, is a selective neuronal potassium channel opener that also has NMDA receptor antagonist properties.",420.39,"75507-68-5",{"v":84,"d":"84.00"},199.81,"<1","N/A","http://selleckchem.com/products/Flupirtine-maleate.html","C15H17FN4O2.C4H4O4","Maleate","N/A","CCOC(=O)NC1=C(N)N=C(NCC2=CC=C(F)C=C2)C=C1.OC(=O)\\C=C\\C(O)=O",{"v":2.76,"d":"2.760"},5,3,8]
["S1336","Fluvoxamine (DU-23000) maleate","c6","L8000-02","in 10mM DMSO","Serotonin Transporter","Neuronal Signaling","Fluvoxamine maleate (DU-23000, MK-264) is a selective serotonin (5-HT) reuptake inhibitor (SSRI), used in the treatment of obsessive-compulsive disorder.",434.41,"61718-82-9",{"v":87,"d":"87.00"},200.27,"<1","N/A","http://selleckchem.com/products/Fluvoxamine-maleate.html","C19H25F3N2O6","Maleate","MK-264,DU-23000 maleate","COCCCCC(=N\\OCCN)/C1=CC=C(C=C1)C(F)(F)F.OC(=O)\\C=C/C(O)=O",0.111,5,1,12]
["S1340","Gatifloxacin","d6","L8000-02","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Gatifloxacin (AM-1155, CG5501, BMS-206584) is an antibiotic of the fourth-generation fluoroquinolone family, and inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.",375.39,"112811-59-3",{"v":7,"d":"7.00"},18.65,"<1","N/A","http://selleckchem.com/products/Gatifloxacin.html","C19H22FN3O4","free base","AM-1155, CG5501, BMS-206584","COC1=C2N(C=C(C(O)=O)C(=O)C2=CC(=C1N3CCNC(C)C3)F)C4CC4",-0.909,3,1,4]
["S1342","Genistein (NPI 031L)","e6","L8000-02","in 10mM DMSO","EGFR,Topoisomerase","Protein Tyrosine Kinase","Genistein (NPI 031L), a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK)  which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM.",270.24,"446-72-0",{"v":54,"d":"54.00"},199.82,"<1","N/A","http://selleckchem.com/products/Genistein.html","C15H10O5","free base","NPI 031L","OC1=CC=C(C=C1)C2=COC3=C(C(=CC(=C3)O)O)C2=O",{"v":2.14,"d":"2.140"},2,3,1]
["S1344","Glimepiride","f6","L8000-02","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Glimepiride(HOE-490) is a potent Kir6.2/SUR inhibitor with IC50 of 3.0 nM, 5.4 nM, and 7.3 nM for SUR1, SUR2A and SUR2B, used in the treatment of type 2 diabetes mellitus.",490.62,"93479-97-1",{"v":11,"d":"11.00"},22.42,"<1","N/A","http://selleckchem.com/products/Glimepiride.html","C24H34N4O5S","free base","HOE-490","CCC1=C(C)CN(C(=O)NCCC2=CC=C(C=C2)[S](=O)(=O)NC(=O)NC3CCC(C)CC3)C1=O",3.781,5,3,7]
["S1351","Ivermectin (MK-933)","g6","L8000-02","in 10mM DMSO","AChR,Autophagy,Chloride Channel,COVID-19,HIV,Mitophagy,P2 Receptor","Transmembrane Transporters","Ivermectin (MK-933, IVM) is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug. Ivermectin (MK-933, IVM) is a specific positive allosteric effector of P2X4 and α7 nicotinic acetylcholine receptors (nAChRs). Ivermectin has potent antiviral activity towards both HIV-1 and dengue virus. Ivermectin induces autophagy through the AKT/mTOR signaling pathway and mitophagy.",875.09,"70288-86-7",{"v":100,"d":"100.00"},114.27,"<1","N/A","http://selleckchem.com/products/Ivermectin.html","C48H74O14","Free Base","MK-933","CCC(C)C1OC2(CCC1C)CC3CC(C\\C=C(C)\\C(OC4CC(OC)C(OC5CC(OC)C(O)C(C)O5)C(C)O4)C(C)\\C=C\\C=C\\6COC7C(O)C(=CC(C(=O)O3)C67O)C)O2",4.743,11,2,8]
["S1354","Lansoprazole","h6","L8000-02","in 10mM DMSO","ATPase,Proton Pump","Transmembrane Transporters","Lansoprazole (A-65006, AG-1749) is a proton-pump inhibitor (PPI) that binds covalently to parietal cell H(+),K(+)-ATPase. Lansoprazole prevents the stomach from producing gastric acid.",369.36,"103577-45-3",{"v":74,"d":"74.00"},200.35,"<1","N/A","http://selleckchem.com/products/Lansoprazole.html","C16H14F3N3O2S","free base","A-65006, AG-1749","CC1=C(OCC(F)(F)F)C=CN=C1C[S](=O)C2=NC3=CC=CC=C3[NH]2",3.442,4,1,6]
["S1357","Lidocaine","a7","L8000-02","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.",234.34,"137-58-6",{"v":47,"d":"47.00"},200.56,{"v":9,"d":"9.00"},38.41,"http://selleckchem.com/products/Lidocaine.html","C14H22N2O","Free Base","Alphacaine","CCN(CC)CC(=O)NC1=C(C)C=CC=C1C",2.626,1,1,5]
["S1358","Loratadine (SCH29851)","b7","L8000-02","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Loratadine (Alavert,Claritin,SCH29851) is a histamine H1 receptor antagonist, used to treat allergies. Also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.",382.88,"79794-75-5",{"v":17,"d":"17.00"},{"v":44.4,"d":"44.40"},"<1","N/A","http://selleckchem.com/products/Loratadine.html","C22H23ClN2O2","free base","Alavert,Claritin,SCH29851","CCOC(=O)N1CCC(CC1)=C2C3=C(CCC4=C2N=CC=C4)C=C(Cl)C=C3",{"v":5,"d":"5.000"},3,0,2]
["S1359","Losartan Potassium (DuP 753)","c7","L8000-02","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Losartan Potassium (DuP 753, MK 954) is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.",462.01,"124750-99-8",{"v":92,"d":"92.00"},199.13,{"v":92,"d":"92.00"},199.13,"http://selleckchem.com/products/losartan-potassium.html","C22H23ClKN6O","Potassium salt","MK 954,DuP 753","[KH].CCCCC1=NC(=C(CO)[N]1CC2=CC=C(C=C2)C3=C(C=CC=C3)C4=NN=N[NH]4)Cl",4.241,4,2,8]
["S1367","Amonafide","d7","L8000-02","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Amonafide (NSC308847, AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage. Phase 3.",283.33,"69408-81-7",{"v":57,"d":"57.00"},201.18,"<1","N/A","http://selleckchem.com/products/Amonafide.html","C16H17N3O2","free base","NSC308847,AS1413","CN(C)CCN1C(=O)C2=C3C(=CC=C2)C=C(N)C=C3C1=O",1.162,2,1,3]
["S1368","Acitretin","e7","L8000-02","in 10mM DMSO","Retinoid Receptor","Metabolism","Acitretin (Etretin, RO 10-1670) is a second generation retinoid used for psoriasis.",326.43,"55079-83-9",{"v":20,"d":"20.00"},61.27,"<1","N/A","http://selleckchem.com/products/Acitretin.html","C21H26O3","free base","Etretin, RO 10-1670","COC1=CC(=C(\\C=C\\C(C)=C\\C=C\\C(C)=C\\C(O)=O)C(=C1C)C)C",5.665,2,0,6]
["S1373","Daptomycin (LY146032)","f7","L8000-02","in 10mM DMSO","Antibiotics,Antibiotics for Mammalian Cell Culture,Bacterial,DNA/RNA Synthesis","DNA Damage/DNA Repair","Daptomycin (Cubicin,LY146032) is a novel antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.",1620.67,"103060-53-3",{"v":100,"d":"100.00"},{"v":61.7,"d":"61.70"},{"v":100,"d":"100.00"},{"v":61.7,"d":"61.70"},"http://selleckchem.com/products/Daptomycin.html","C72H101N17O26","free base","Cubicin,LY146032","CCCCCCCCCC(=O)NC(CC1=C[NH]C2=C1C=CC=C2)C(=O)NC(CC(N)=O)C(=O)NC(CC(O)=O)C(=O)NC3C(C)OC(=O)C(CC(=O)C4=CC=CC=C4N)NC(=O)C(NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CCCN)NC(=O)CNC3=O)C(C)CC(O)=O",-7.895,21,18,35]
["S1376","Gestodene","g7","L8000-02","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Gestodene (SH B 331,WL 70) is a progestogen hormonal contraceptive.",310.43,"60282-87-3",{"v":62,"d":"62.00"},199.72,"<1","N/A","http://selleckchem.com/products/Gestodene.html","C21H26O2","free base","SH B 331,WL 70","CCC12CCC3C(CCC4=CC(=O)CCC34)C1C=CC2(O)C#C",4.462,1,0,1]
["S1377","Drospirenone","h7","L8000-02","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Drospirenone (ZK 3059) is a synthetic progestin that is an analog to spironolactone.",366.49,"67392-87-4",{"v":73,"d":"73.00"},199.19,"<1","N/A","http://selleckchem.com/products/Drospirenone.html","C24H30O3","free base","ZK 3059","CC12CCC(=O)C=C1C3CC3C4C2CCC5(C)C4C6CC6C57CCC(=O)O7",3.383,3,0,0]
["S1378","Ruxolitinib (INCB018424)","a8","L8000-02","in 10mM DMSO","Apoptosis related,Autophagy,JAK,Mitophagy","JAK/STAT","Ruxolitinib (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis.",306.37,"941678-49-5",{"v":61,"d":"61.00"},199.11,"<1","N/A","http://selleckchem.com/products/INCB18424.html","C17H18N6","free base","INCB018424","N#CCC(C1CCCC1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4",{"v":2.88,"d":"2.880"},3,1,4]
["S1379","Isotretinoin","b8","L8000-02","in 10mM DMSO","Hydroxylase","Metabolism","Isotretinoin (13-cis retinoic acid) was developed to be used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more.",300.44,"4759-48-2",{"v":60,"d":"60.00"},199.71,"<1","N/A","http://selleckchem.com/products/Isotretinoin.html","C20H28O2","free base","13-cis retinoic acid","CC1=C(\\C=C\\C(C)=C\\C=C\\C(C)=C/C(O)=O)C(C)(C)CCC1",5.551,1,0,5]
["S1385","Mosapride Citrate","c8","L8000-02","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Mosapride Citrate (TAK-370, AS-4370, Gasmotin) is a gastroprokinetic agent that acts as a selective 5HT4 agonist.",614.02,"112885-42-4",{"v":90,"d":"90.00"},146.58,"<1","N/A","http://selleckchem.com/products/Mosapride-citrate.html","C21H25ClFN3O3.C6H8O7","Citrate","TAK-370, AS-4370, Gasmotin","CCOC1=CC(=C(Cl)C=C1C(=O)NCC2CN(CCO2)CC3=CC=C(F)C=C3)N.OC(=O)CC(O)(CC(O)=O)C(O)=O",-1.422,6,2,12]
["S1386","Nafamostat mesilate (FUT-175)","d8","L8000-02","in 10mM DMSO","Apoptosis related,COVID-19,SARS-CoV,Serine Protease","Proteases","Nafamostat mesilate (Futhan, FUT-175) is a synthetic serine protease inhibitor, used as an anticoagulant during hemodialysis. Nafamostat mesylate blocks activation of SARS-CoV-2 and is investigated as a new treatment option for COVID-19. Nafamostat Mesilate attenuates inflammation and apoptosis.",539.58,"82956-11-4",{"v":20,"d":"20.00"},37.07,{"v":53,"d":"53.00"},98.22,"http://selleckchem.com/products/Nafamostat-mesylate.html","C19H17N5O2.2CH4O3S","Dimesylate","Futhan, FUT-175","C[S](O)(=O)=O.C[S](O)(=O)=O.NC(=N)NC1=CC=C(C=C1)C(=O)OC2=CC3=C(C=C2)C=C(C=C3)C(N)=N",1.364,2,3,6]
["S1387","Naftopidil DiHCl","e8","L8000-02","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Naftopidil DiHCl (Flivas, KT-611, Avishot,BM-15275) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.",465.41,"57149-08-3",{"v":41,"d":"41.00"},88.09,"<1","N/A","http://selleckchem.com/products/Naftopidil-Dihydrochloride.html","C24H28N2O3.2HCl","Dihydrochloride","Flivas, KT-611, Avishot,BM-15275","Cl.Cl.COC1=CC=CC=C1N2CCN(CC2)CC(O)COC3=C4C=CC=CC4=CC=C3",4.726,2,1,7]
["S1389","Omeprazole","f8","L8000-02","in 10mM DMSO","ATPase,Autophagy,Proton Pump","Transmembrane Transporters","Omeprazole is a proton pump inhibitor that blocks H(+)-K(+)-ATPase, used to treat dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, laryngopharyngeal reflux, and Zollinger–Ellison syndrome.",345.42,"73590-58-6",{"v":69,"d":"69.00"},199.76,"<1","N/A","http://selleckchem.com/products/Omeprazole.html","C17H19N3O3S","free base","N/A","COC1=CC=C2[NH]C(=NC2=C1)[S](=O)CC3=C(C)C(=C(C)C=N3)OC",2.904,5,1,5]
["S1390","Ondansetron HCl","g8","L8000-02","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Ondansetron HCl (Ondemet, Emeset, Emetron,GR 38032F,SN 307) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation therapy.",329.82,"99614-01-4",{"v":66,"d":"66.00"},200.11,{"v":24,"d":"24.00"},72.77,"http://selleckchem.com/products/Ondansetron-hydrochloride.html","C18H19N3O.HCl","Hydrochloride","Ondemet, Emeset, Emetron,GR 38032F,SN 307","Cl.C[N]1C2=C(C(=O)C(CC2)C[N]3C=CN=C3C)C4=CC=CC=C14",3.016,2,0,2]
["S1391","Oxcarbazepine","h8","L8000-02","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Oxcarbazepine (GP47680) inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM.",252.27,"28721-07-5",{"v":7,"d":"7.00"},27.75,"<1","N/A","http://selleckchem.com/products/Oxcarbazepine.html","C15H12N2O2","free base","GP47680","NC(=O)N1C2=C(CC(=O)C3=C1C=CC=C3)C=CC=C2",2.131,2,1,0]
["S1393","Pirarubicin (NSC-333054)","a9","L8000-02","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,Topoisomerase","DNA Damage/DNA Repair","Pirarubicin (NSC-333054,THP) is an anthracycline antibiotic, and also a DNA/RNA synthesis inhibitor by intercalating into DNA and interacts with topoisomerase II, used as an antineoplastic agent.",627.64,"72496-41-4",{"v":7,"d":"7.00"},11.15,"<1","N/A","http://selleckchem.com/products/Pirarubicin.html","C32H37NO12","free base","NSC-333054,THP","COC1=CC=CC2=C1C(=O)C3=C(O)C4=C(CC(O)(CC4OC5CC(N)C(OC6CCCCO6)C(C)O5)C(=O)CO)C(=C3C2=O)O",1.091,8,4,7]
["S1394","Pizotifen Malate","b9","L8000-02","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Pizotifen Malate (Sandomigran, pizotyline,BC-105) is a benzocycloheptane based agent used for recurrent migraine headaches.",429.53,"5189-11-7",{"v":21,"d":"21.00"},48.89,"<1","N/A","http://selleckchem.com/products/Pizotifen-malate.html","C19H21NS.C4H6O5","Malate","Sandomigran, pizotyline,BC-105","CN1CCC(CC1)=C2C3=C(CCC4=C2C=CC=C4)SC=C3.OC(CC(O)=O)C(O)=O",0.292,2,1,3]
["S1396","Resveratrol (SRT501)","c9","L8000-02","in 10mM DMSO","AMPK,Apoptosis related,Autophagy,COX,ERK,IκB/IKK,JNK,Lipoxygenase,Mitophagy,Sirtuin,Src,STAT","Autophagy","Resveratrol (SRT501, trans-Resveratrol) has a wide spectrum of targets including cyclooxygenases(i.e. COX, IC50=1.1 μM), lipooxygenases（LOX, IC50=2.7 μM）, kinases, sirtuins and other proteins. It has anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects. Resveratrol induces mitophagy/autophagy and autophagy-dependent apoptosis.",228.24,"501-36-0",{"v":45,"d":"45.00"},197.16,"<1","N/A","http://selleckchem.com/products/Resveratrol.html","C14H12O3","free base","trans-Resveratrol,SRT501","OC1=CC=C(C=C1)\\C=C\\C2=CC(=CC(=C2)O)O",{"v":3.09,"d":"3.090"},0,3,2]
["S1397","Rocuronium Bromide","d9","L8000-02","in 10mM DMSO","AChR","Neuronal Signaling","Rocuronium Bromide (ORG 9426) is a competitive AchR antagonist, used in modern anaesthesia.",609.68,"119302-91-9",{"v":122,"d":"122.00"},{"v":200.1,"d":"200.10"},{"v":122,"d":"122.00"},{"v":200.1,"d":"200.10"},"http://selleckchem.com/products/Rocuronium-bromide.html","C32H53N2O4.Br","Bromide","ORG 9426","[Br-].CC(=O)OC1C(CC2C3CCC4CC(O)C(CC4(C)C3CCC12C)N5CCOCC5)[N+]6(CCCC6)CC=C",0.282,3,1,6]
["S1398","Stavudine (d4T)","e9","L8000-02","in 10mM DMSO","Reverse Transcriptase","Microbiology","Stavudine (d4T, BMY-27857, Sanilvudine, NSC 163661) is a nucleoside analog reverse transcriptase inhibitor (NARTI) active against HIV.",224.21,"3056-17-5",{"v":45,"d":"45.00"},{"v":200.7,"d":"200.70"},"<1","N/A","http://selleckchem.com/products/Stavudine.html","C10H12N2O4","free base","BMY-27857, Sanilvudine, NSC 163661,d4T","CC1=CN(C2OC(CO)C=C2)C(=O)NC1=O",-0.515,3,2,2]
["S1401","Tenofovir","f9","L8000-02","in 10mM DMSO","Antiviral,COVID-19,Reverse Transcriptase","Microbiology","Tenofovir (GS-1278) blocks reverse transcriptase and hepatitis B virus infections.",287.21,"147127-20-6",{"v":4,"d":"4.00"},13.93,{"v":2,"d":"2.00"},6.96,"http://selleckchem.com/products/Tenofovir.html","C9H14N5O4P","free base","GS-1278","CC(C[N]1C=NC2=C(N)N=CN=C12)OC[P](O)(O)=O",-0.772,4,1,5]
["S1403","Tigecycline (GAR-936)","g9","L8000-02","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,Autophagy,Bacterial","Microbiology","Tigecycline (Tygacil, GAR-936, WAY-GAR-936, TBG-MINO) is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline induces autophagy by downregulating the PI3K-AKT-mTOR pathway.",585.65,"220620-09-7",{"v":100,"d":"100.00"},170.75,{"v":100,"d":"100.00"},170.75,"http://selleckchem.com/products/Tigecycline.html","C29H39N5O8","free base","Tygacil, GAR-936, WAY-GAR-936, TBG-MINO","CN(C)C1C2CC3CC4=C(C(=C(NC(=O)CNC(C)(C)C)C=C4N(C)C)O)C(=O)C3=C(O)C2(O)C(=O)C(=C1O)C(N)=O",-0.381,4,6,7]
["S1404","Trilostane","h9","L8000-02","in 10mM DMSO","Dehydrogenase","Metabolism","Trilostane (WIN 24540) is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing’s syndrome.",329.43,"13647-35-3",{"v":65,"d":"65.00"},197.31,"<1","N/A","http://selleckchem.com/products/Trilostane.html","C20H27NO3","free base","WIN 24540","CC12CCC3C(CCC45OC4C(=C(CC35C)C#N)O)C1CCC2O",2.434,1,2,0]
["S1405","Vecuronium Bromide","a10","L8000-02","in 10mM DMSO","AChR","Neuronal Signaling","Vecuronium Bromide (ORG NC45) is a non-depolarizing neuromuscular blocking agent, used for skeletal muscle relaxation during surgery.",637.73,"50700-72-6",{"v":100,"d":"100.00"},156.81,{"v":4,"d":"4.00"},6.27,"http://selleckchem.com/products/Vecuronium-Bromide.html","C34H57N2O4.Br","Bromide","ORG NC45","[Br-].CC(=O)OC1CC2CCC3C(CCC4(C)C3CC(C4OC(C)=O)[N+]5(C)CCCCC5)C2(C)CC1N6CCCCC6",{"v":1.73,"d":"1.730"},4,0,6]
["S1407","Bimatoprost","b10","L8000-02","in 10mM DMSO","Prostaglandin Receptor","GPCR & G Protein","Bimatoprost(AGN 192024) is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.",415.57,"155206-00-1",{"v":36,"d":"36.00"},86.63,"<1","N/A","http://selleckchem.com/products/Bimatoprost.html","C25H37NO4","free base","AGN 192024","CCNC(=O)CCC\\C=C/CC1C(O)CC(O)C1/C=C/C(O)CCC2=CC=CC=C2",{"v":3.03,"d":"3.030"},1,4,12]
["S1408","Linezolid (PNU-100766)","c10","L8000-02","in 10mM DMSO","Antibiotics","Microbiology","Linezolid (Zyvoxid, Zyvoxam,PNU-100766) is a synthetic antibiotic used for the treatment of serious infections.",337.35,"165800-03-3",{"v":67,"d":"67.00"},198.61,"<1","N/A","http://selleckchem.com/products/Linezolid(Zyvox).html","C16H20FN3O4","free base","Zyvoxid, Zyvoxam,PNU-100766","CC(=O)NCC1CN(C(=O)O1)C2=CC=C(N3CCOCC3)C(=C2)F",0.894,4,1,4]
["S1409","Alfuzosin HCl","d10","L8000-02","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Alfuzosin HCI(SL 77499 HCl)  is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH).",425.91,"81403-68-1",{"v":85,"d":"85.00"},199.57,{"v":85,"d":"85.00"},199.57,"http://selleckchem.com/products/Alfuzosin-hydrochloride.html","C19H27N5O4.HCl","Hydrochloride","SL 77499 HCl","Cl.COC1=C(OC)C=C2C(=NC(=NC2=C1)N(C)CCCNC(=O)C3CCCO3)N",{"v":1.8,"d":"1.800"},6,2,8]
["S1425","Ranolazine 2HCl","e10","L8000-02","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Ranolazine 2HCl (RS-43285,RS 43285-193,Ranexa, renolazine,Ranolazine dihydrochloride) is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina.",500.46,"95635-56-6",{"v":100,"d":"100.00"},199.82,{"v":100,"d":"100.00"},199.82,"http://selleckchem.com/products/Ranolazine-dihydrochloride.html","C24H33N3O4.2HCl","Dihydrochloride","RS-43285,RS 43285-193,Ranexa, renolazine,Ranolazine dihydrochloride","Cl.Cl.COC1=CC=CC=C1OCC(O)CN2CCN(CC2)CC(=O)NC3=C(C)C=CC=C3C",3.755,3,2,9]
["S1426","Repaglinide","f10","L8000-02","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Repaglinide (AG-EE 623 ZW) is a potassium channel blocker, which lowers blood glucose by stimulating the release of insulin from the pancreas, used the treatment of type II diabetes.",452.59,"135062-02-1",{"v":91,"d":"91.00"},201.06,"<1","N/A","http://selleckchem.com/products/Repaglinide.html","C27H36N2O4","free base","AG-EE 623 ZW","CCOC1=C(C=CC(=C1)CC(=O)NC(CC(C)C)C2=CC=CC=C2N3CCCCC3)C(O)=O",5.307,3,1,10]
["S1430","Rolipram (ZK-62711)","g10","L8000-02","in 10mM DMSO","PDE","Metabolism","The PDE4 selective inhibitor, Rolipram (ZK-62711, SB 95952), inhibited immunopurified PDE4B and PDE4D activities similarly, with IC50 values of approx. 130 nM and 240 nM respectively; an anti-inflammatory agent.",275.34,"61413-54-5",{"v":55,"d":"55.00"},199.75,"<1","N/A","http://selleckchem.com/products/Rolipram.html","C16H21NO3","free base","ZK-62711, SB 95952","COC1=C(OC2CCCC2)C=C(C=C1)C3CNC(=O)C3",2.349,3,1,4]
["S1431","Sildenafil Citrate","h10","L8000-02","in 10mM DMSO","PDE","Metabolism","Sildenafil Citrate, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), is a well-tolerated and highly effective treatment for erectile dysfunction.",{"v":666.7,"d":"666.70"},"171599-83-0",{"v":20,"d":"20.00"},{"v":30,"d":"30.00"},"<1","N/A","http://selleckchem.com/products/Sildenafil-citrate.html","C22H30N6O4S.C6H8O7","Citrate","N/A","CCCC1=N[N](C)C2=C1N=C(NC2=O)C3=CC(=CC=C3OCC)[S](=O)(=O)N4CCN(C)CC4.OC(=O)CC(O)(CC(O)=O)C(O)=O",-2.107,9,1,12]
["S1432","Sumatriptan Succinate","a11","L8000-02","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Sumatriptan Succinate (GR 43175) is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches.",413.49,"103628-48-4",{"v":83,"d":"83.00"},200.73,{"v":83,"d":"83.00"},200.73,"http://selleckchem.com/products/Sumatriptan-succinate.html","C14H21N3O2S.C4H6O4","Succinate","GR 43175","CN[S](=O)(=O)CC1=CC=C2[NH]C=C(CCN(C)C)C2=C1.OC(=O)CCC(O)=O",-1.958,4,2,9]
["S1437","Tizanidine HCl","c11","L8000-02","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Tizanidine HCl (DS 103-282) is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.",290.17,"64461-82-1",{"v":10,"d":"10.00"},34.46,{"v":15,"d":"15.00"},51.69,"http://selleckchem.com/products/Tizanidine-hydrochloride.html","C9H8ClN5S.HCl","Hydrochloride","DS 103-282","Cl.ClC1=C(NC2=NCCN2)C3=NSN=C3C=C1",2.199,3,2,2]
["S1438","Topiramate","d11","L8000-02","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Topiramate (MCN 4853, RWJ 17021) is a mutil-targeted inhibitor, including voltage-gated sodium channel and calcium channel, AMPA/kainate receptor and carbonic anhydrase, used to treat epilepsy.",339.36,"97240-79-4",{"v":68,"d":"68.00"},200.38,"<1","N/A","http://selleckchem.com/products/Topiramate.html","C12H21NO8S","free base","MCN 4853, RWJ 17021","CC1(C)OC2COC3(CO[S](N)(=O)=O)OC(C)(C)OC3C2O1",-1.932,6,1,3]
["S1439","Tranilast (SB 252218)","e11","L8000-02","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Tranilast (SB 252218, MK-341, Rizaben, MK 341, Tranpro) is an antiallergic drug by inhibiting lipid mediator and cytokine release from inflammatory cells, used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.",327.33,"53902-12-8",{"v":66,"d":"66.00"},201.63,"<1","N/A","http://selleckchem.com/products/Tranilast.html","C18H17NO5","free base","SB 252218, MK-341, Rizaben, MK 341, Tranpro","COC1=C(OC)C=C(\\C=C\\C(=O)NC2=CC=CC=C2C(O)=O)C=C1",2.679,4,1,6]
["S1441","Venlafaxine HCl","f11","L8000-02","in 10mM DMSO","Serotonin Transporter","Neuronal Signaling","Venlafaxine HCl(Wy 453 HCl) is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.",313.86,"99300-78-4",{"v":55.5,"d":"55.50"},176.83,{"v":55.5,"d":"55.50"},176.83,"http://selleckchem.com/products/Venlafaxine-hydrochloride.html","C17H27NO2.HCl","Hydrochloride","Wy 453 HCl","Cl.COC1=CC=C(C=C1)C(CN(C)C)C2(O)CCCCC2",3.404,1,0,5]
["S1442","Voriconazole (UK-109496)","g11","L8000-02","in 10mM DMSO","Fungal,P450 (e.g. CYP17)","Metabolism","Voriconazole (Vfend,UK-109496) is a new triazole derivative similar to fluconazole and itraconazole that acts by inhibiting fungal cytochrome P-450-dependent, 14-alpha-sterol demethylase-mediated synthesis of ergosterol.",349.31,"137234-62-9",{"v":70,"d":"70.00"},{"v":200.4,"d":"200.40"},"<1","N/A","http://selleckchem.com/products/Voriconazole.html","C16H14F3N5O","free base","Vfend,UK-109496","CC(C1=NC=NC=C1F)C(O)(C[N]2C=NC=N2)C3=CC=C(F)C=C3F",2.071,4,0,5]
["S1443","Zileuton (A-64077)","h11","L8000-02","in 10mM DMSO","Apoptosis related,Ferroptosis,Lipoxygenase","Metabolism","Zileuton (A-64077, Abbott 64077, ZYFLO) is an orally active inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation, used to decrease the symptoms of asthma. Zileuton induces apoptosis while inhibits ferroptosis.",236.29,"111406-87-2",{"v":47,"d":"47.00"},198.91,"<1","N/A","http://selleckchem.com/products/Zileuton.html","C11H12N2O2S","free base","A-64077, Abbott 64077, ZYFLO","CC(N(O)C(N)=O)C1=CC2=CC=CC=C2S1",2.184,1,1,2]
["S1444","Ziprasidone HCl","a2","L8000-03","in 10mM DMSO","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Ziprasidone HCl (CP-88059) is a novel and potent dopamine and serotonin (5-HT) receptor antagonist, used in the treatment of schizophrenia and bipolar disorder.",{"v":449.4,"d":"449.40"},"122883-93-6",{"v":90,"d":"90.00"},200.27,"<1","N/A","http://selleckchem.com/products/Ziprasidone-hydrochloride.html","C21H21ClN4OS.HCl","Hydrochloride","CP-88059","Cl.ClC1=CC2=C(CC(=O)N2)C=C1CCN3CCN(CC3)C4=NSC5=C4C=CC=C5",4.641,2,1,4]
["S1445","Zonisamide","b2","L8000-03","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Zonisamide (Zonegran,CI-912,AD 810) is a voltage-dependent sodium channel and T-type calcium channel blocker, used as an antiepileptic drug.",212.23,"68291-97-4",{"v":42,"d":"42.00"},{"v":197.9,"d":"197.90"},"<1","N/A","http://selleckchem.com/products/Zonisamide.html","C8H8N2O3S","free base","Zonegran,CI-912,AD 810","N[S](=O)(=O)CC1=NOC2=CC=CC=C12",0.411,4,1,2]
["S1453","Tipifarnib (R115777)","c2","L8000-03","in 10mM DMSO","FTase,Transferase","Metabolism","Tipifarnib (R115777, IND 58359) is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM, its anti-proliferative effects are most prominent in H-ras or N-ras mutant cells. Phase 3.",{"v":489.4,"d":"489.40"},"192185-72-1",{"v":14,"d":"14.00"},28.61,"<1","N/A","http://selleckchem.com/products/Tipifarnib(R115777).html","C27H22Cl2N4O","free base","IND 58359","C[N]1C=NC=C1C(N)(C2=CC=C(Cl)C=C2)C3=CC4=C(C=C3)N(C)C(=O)C=C4C5=CC(=CC=C5)Cl",4.808,2,1,4]
["S1457","Atazanavir (BMS-232632) Sulfate","d2","L8000-03","in 10mM DMSO","HIV Protease","Proteases","Atazanavir Sulfate (BMS-232632-05, Reyataz) is a HIV protease inhibitor with Ki of 2.66 nM in a cell-free assay.",802.93,"229975-97-7",{"v":104,"d":"104.00"},129.53,"<1","N/A","http://selleckchem.com/products/Atazanavir.html","C38H52N6O7.H2SO4","Sulfate","BMS-232632-05, Reyataz","COC(=O)NC(C(=O)NC(CC1=CC=CC=C1)C(O)CN(CC2=CC=C(C=C2)C3=NC=CC=C3)NC(=O)C(NC(=O)OC)C(C)(C)C)C(C)(C)C.O[S](O)(=O)=O",4.083,7,5,18]
["S1458","Neflamapimod (VX-745)","e2","L8000-03","in 10mM DMSO","p38 MAPK","MAPK","Neflamapimod (VX-745) is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ.",436.26,"209410-46-8",{"v":15,"d":"15.00"},34.38,"<1","N/A","http://selleckchem.com/products/VX-745.html","C19H9Cl2F2N3OS","free base","N/A","FC1=CC(=C(SC2=NN3C=NC(=O)C(=C3C=C2)C4=C(Cl)C=CC=C4Cl)C=C1)F",5.342,3,0,3]
["S1465","Moxifloxacin (BAY12-8039) HCl","f2","L8000-03","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Moxifloxacin (Avelox, Avalox,BAY12-8039 HCl) is a fourth-generation synthetic fluoroquinolone antibacterial agent.",437.89,"186826-86-8",{"v":87,"d":"87.00"},198.68,{"v":60,"d":"60.00"},137.02,"https://www.selleckchem.com/products/Moxifloxacin-hcl.html","C21H24FN3O4.HCl","Hydrochloride","Avelox, Avalox,BAY12-8039 HCl","Cl.COC1=C2N(C=C(C(O)=O)C(=O)C2=CC(=C1N3CC4CCCNC4C3)F)C5CC5",{"v":-0.32,"d":"-0.320"},3,1,4]
["S1467","Doxercalciferol","h2","L8000-03","in 10mM DMSO","Vitamin","Metabolism","Doxercalciferol (1α-hydroxyvitamin D2) is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.",412.65,"54573-75-0",{"v":83,"d":"83.00"},201.14,"<1","N/A","http://selleckchem.com/products/Doxercalciferol(Hectorol).html","C28H44O2","free base","1α-hydroxyvitamin D2","CC(C)C(C)/C=C/C(C)C1CCC2C(/CCCC12C)=C/C=C/3CC(O)CC(O)C3=C",6.337,0,2,5]
["S1468","Alfacalcidol","a3","L8000-03","in 10mM DMSO","Vitamin","Metabolism","Alfacalcidol (1-hydroxycholecalciferol) is a non-selective VDR activator medication.",400.64,"41294-56-8",{"v":80,"d":"80.00"},199.68,"<1","N/A","http://selleckchem.com/products/Alfacalcidol.html","C27H44O2","free base","1-hydroxycholecalciferol","CC(C)CCCC(C)C1CCC2/C(CCCC12C)=C\\C=C3/CC(O)CC(O)C3=C",{"v":6.53,"d":"6.530"},0,2,6]
["S1483","Iloperidone","b3","L8000-03","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Iloperidone (HP873) is a dopamine (D2)/serotonin (5-HT2) receptor antagonist, used for the treatment of schizophrenia.",426.48,"133454-47-4",{"v":27,"d":"27.00"},63.31,"<1","N/A","http://selleckchem.com/products/Iloperidone(Fanapt).html","C24H27FN2O4","free base","HP873","COC1=C(OCCCN2CCC(CC2)C3=NOC4=C3C=CC(=C4)F)C=CC(=C1)C(C)=O",4.016,5,0,8]
["S1485","HMN-214","c3","L8000-03","in 10mM DMSO","PLK","Cell Cycle","HMN-214 is a prodrug of HMN-176, which alters the cellular spatial orientation of Plk1.",424.47,"173529-46-9",{"v":12,"d":"12.00"},28.27,"<1","N/A","http://selleckchem.com/products/HMN-214.html","C22H20N2O5S","free base","N/A","COC1=CC=C(C=C1)[S](=O)(=O)N(C(C)=O)C2=C(C=CC=C2)\\C=C\\C3=CC=[N+]([O-])C=C3",2.282,4,0,6]
["S1488","Naratriptan HCl","d3","L8000-03","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Naratriptan HCl is a triptan agent that is used for the treatment of migraine headaches.",371.93,"143388-64-1",{"v":74,"d":"74.00"},198.96,{"v":22,"d":"22.00"},59.15,"http://selleckchem.com/products/Naratriptan(Amerge).html","C17H25N3O2S.HCl","Hydrochloride","N/A","Cl.CN[S](=O)(=O)CCC1=CC=C2[NH]C=C(C3CCN(C)CC3)C2=C1",2.435,2,2,5]
["S1490","Ponatinib (AP24534)","e3","L8000-03","in 10mM DMSO","Autophagy,Bcr-Abl,FGFR,PDGFR,Src,VEGFR","Angiogenesis","Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively. Ponatinib (AP24534) inhibits autophagy.",532.56,"943319-70-8",{"v":30,"d":"30.00"},56.33,"<1","N/A","http://selleckchem.com/products/AP24534.html","C29H27F3N6O","free base","AP24534","CN1CCN(CC1)CC2=C(C=C(NC(=O)C3=CC(=C(C)C=C3)C#CC4=CN=C5C=CC=N[N]45)C=C2)C(F)(F)F",4.884,3,1,7]
["S1491","Fludarabine (NSC 118218)","f3","L8000-03","in 10mM DMSO","Apoptosis related,DNA/RNA Synthesis,Nucleoside Analog/Antimetabolite,STAT","JAK/STAT","Fludarabine (NSC 118218, FaraA, Fludarabinum) is a STAT1 activation inhibitor which causes a specific depletion of STAT1 protein (and mRNA) but not of other STATs. Also a DNA synthesis inhibitor in vascular smooth muscle cells. Fludarabine induces apoptosis.",285.23,"21679-14-1",{"v":57,"d":"57.00"},199.84,"<1","N/A","http://selleckchem.com/products/Fludarabine(Fludara).html","C10H12FN5O4","Free Base","FaraA, Fludarabinum, NSC 118218","NC1=NC(=NC2=C1N=C[N]2C3OC(CO)C(O)C3O)F",-1.312,4,4,2]
["S1497","Pralatrexate (NSC 754230)","g3","L8000-03","in 10mM DMSO","Apoptosis related,DHFR","Metabolism","Pralatrexate (NSC 754230) is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines. Pralatrexate induces tumor cell apoptosis.",477.47,"146464-95-1",{"v":28,"d":"28.00"},58.64,"<1","N/A","http://selleckchem.com/products/Pralatrexate(Folotyn).html","C23H23N7O5","free base","NSC 754230","NC1=NC(=C2N=C(CC(CC#C)C3=CC=C(C=C3)C(=O)NC(CCC(O)=O)C(O)=O)C=NC2=N1)N",{"v":1.94,"d":"1.940"},7,3,10]
["S1499","Cefaclor","h3","L8000-03","in 10mM DMSO","Antibiotics","Microbiology","Cefaclor (Cefachlor, Cefaclorum) is a cephalosporin antibiotic.",385.82,"70356-03-5",{"v":11,"d":"11.00"},28.51,"<1","N/A","http://selleckchem.com/products/Cefaclor-(Ceclor).html","C15H14ClN3O4S.H2O","monohydrate","Cefachlor, Cefaclorum","O.NC(C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)Cl)C3=CC=CC=C3",{"v":-2.54,"d":"-2.540"},3,2,4]
["S1500","Betamethasone","a4","L8000-03","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Betamethasone (NSC-39470, SCH-4831) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.",392.46,"378-44-9",{"v":79,"d":"79.00"},201.29,"<1","N/A","http://selleckchem.com/products/Betamethasone-(Celestone).html","C22H29FO5","Free Base","NSC-39470, SCH-4831","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO",1.708,2,2,2]
["S1501","Mycophenolate mofetil (RS-61443)","b4","L8000-03","in 10mM DMSO","Apoptosis related,Dehydrogenase","Metabolism","Mycophenolate Mofetil (RS 61443, Mycophenolic acid morpholinoethyl ester, CellCept, TM-MMF) is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively. Mycophenolate Mofetil induces caspase-dependent apoptosis and cell cycle inhibition in multiple myeloma cells.",433.49,"128794-94-5",{"v":86,"d":"86.00"},198.39,"<1","N/A","http://selleckchem.com/products/Mycophenolate-mofetil-(CellCept).html","C23H31NO7","free base","Mycophenolic acid morpholinoethyl ester, CellCept, RS 61443, TM-MMF","COC1=C(C)C2=C(C(=O)OC2)C(=C1C\\C=C(C)\\CCC(=O)OCCN3CCOCC3)O",3.209,6,1,10]
["S1504","Dyphylline","c4","L8000-03","in 10mM DMSO","PDE","Metabolism","Dyphylline (Diprophylline) is a xanthine derivative with bronchodilator and vasodilator effects.",254.24,"479-18-5",{"v":51,"d":"51.00"},{"v":200.6,"d":"200.60"},{"v":51,"d":"51.00"},{"v":200.6,"d":"200.60"},"http://selleckchem.com/products/Dyphylline(Dilor).html","C10H14N4O4","free base","Diprophylline","CN1C(=O)N(C)C2=C([N](CC(O)CO)C=N2)C1=O",-1.151,3,2,3]
["S1505","Aztreonam","d4","L8000-03","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Aztreonam (SQ 26776) is a synthetic monocyclic beta-lactam antibiotic, used to treat Gram-negative aerobic bacteria infection.",435.43,"78110-38-0",{"v":87,"d":"87.00"},{"v":199.8,"d":"199.80"},{"v":11,"d":"11.00"},25.26,"http://selleckchem.com/products/Aztreonam(Azactam).html","C13H17N5O8S2","free base","SQ 26776","CC1C(NC(=O)\\C(=N/OC(C)(C)C(O)=O)C2=CSC(=N2)N)C(=O)N1[S](O)(=O)=O",-1.035,6,2,7]
["S1512","Tadalafil (IC351)","e4","L8000-03","in 10mM DMSO","PDE","Metabolism","Tadalafil (IC351) is a PDE-5 inhibitor with IC50 of 1.8 nM in a cell-free assay. Tadalafil is at least 9000 times more selective for PDE5 than most of the other families of PDEs, with the exception of PDE11. It can partial inhibits PDE11",{"v":389.4,"d":"389.40"},"171596-29-5",{"v":78,"d":"78.00"},200.31,"<1","N/A","http://selleckchem.com/products/Tadalafil(Cialis).html","C22H19N3O4","free base","IC351","CN1CC(=O)N2C(CC3=C([NH]C4=C3C=CC=C4)C2C5=CC=C6OCOC6=C5)C1=O",2.183,4,1,1]
["S1514","Cyclosporine","f4","L8000-03","in 10mM DMSO","Immunology & Inflammation related,phosphatase","Metabolism","Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.",1202.61,"79217-60-0",{"v":100,"d":"100.00"},83.15,"<1","N/A","http://selleckchem.com/products/Cyclosporine.html","C62H111N11O12","free base","Neoral","CCC1NC(=O)C(C(O)C(C)C\\C=C\\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C",4.333,11,5,15]
["S1517","Natamycin","g4","L8000-03","in 10mM DMSO","Fungal","Microbiology","Natamycin (Pimaricin), a natural and versatile anti-fungal agent during fermentation by the bacterium Streptomyces natalensis, commonly found in soil; with little to no flavour interference",665.73,"7681-93-8",{"v":7,"d":"7.00"},10.51,"<1","N/A","http://selleckchem.com/products/Natamycin(Pimaricin).html","C33H47NO13","free base","Pimaricin","CC1C/C=C/C=C/C=C/C=C/C(CC2OC(O)(CC(O)CC3OC3/C=C/C(=O)O1)CC(O)C2C(O)=O)OC4OC(C)C(O)C(N)C4O",-2.824,7,5,3]
["S1526","Quizartinib (AC220)","h4","L8000-03","in 10mM DMSO","Apoptosis related,FLT3,Target Protein Ligand","Angiogenesis","Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Quizartinib (AC220) induces apoptosis of tumor cells. Phase 3.",560.67,"950769-58-1",{"v":33,"d":"33.00"},58.86,"<1","N/A","http://selleckchem.com/products/AC-220.html","C29H32N6O4S","free base","N/A","CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=C[N]4C(=N3)SC5=CC(=CC=C45)OCCN6CCOCC6",5.064,6,2,8]
["S1547","Febuxostat","a5","L8000-03","in 10mM DMSO","ROS","Immunology & Inflammation","Febuxostat (TMX 67, TEI-6720) is a selective xanthine oxidase inhibitor with Ki of 0.6 nM.",316.37,"144060-53-7",{"v":63,"d":"63.00"},199.13,"<1","N/A","http://selleckchem.com/products/Febuxostat(Uloric).html","C16H16N2O3S","free base","TMX 67, TEI-6720","CC(C)COC1=C(C=C(C=C1)C2=NC(=C(S2)C(O)=O)C)C#N",3.468,3,0,5]
["S1548","Dapagliflozin (BMS-512148)","b5","L8000-03","in 10mM DMSO","SGLT","GPCR & G Protein","Dapagliflozin (BMS-512148) is a potent and selective hSGLT2 inhibitor with EC50 of 1.1 nM, exhibiting 1200-fold selectivity over hSGLT1. Phase 4.",408.87,"461432-26-8",{"v":82,"d":"82.00"},200.55,"<1","N/A","http://selleckchem.com/products/Dapagliflozin.html","C21H25ClO6","free base","BMS-512148","CCOC1=CC=C(CC2=CC(=CC=C2Cl)C3OC(CO)C(O)C(O)C3O)C=C1",2.409,2,4,6]
["S1549","Nebivolol hydrochloride (R-65824)","c5","L8000-03","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Nebivolol HCl (R-65824) selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM.",{"v":441.9,"d":"441.90"},"152520-56-4",{"v":88,"d":"88.00"},199.14,"<1","N/A","http://selleckchem.com/products/Nebivolol(Bystolic).html","C22H25F2NO4.HCl","Hydrochloride","R-65824 hydrochloride","Cl.OC(CNCC(O)C1CCC2=C(O1)C=CC(=C2)F)C3CCC4=CC(=CC=C4O3)F",3.939,2,3,6]
["S1550","Pimobendan","d5","L8000-03","in 10mM DMSO","PDE","Metabolism","Pimobendan (UD-CG 115 BS) is a selective inhibitor of PDE3 with IC50 of 0.32 μM.",334.37,"74150-27-9",{"v":67,"d":"67.00"},200.38,"<1","N/A","http://selleckchem.com/products/Pimobendan(Vetmedin).html","C19H18N4O2","free base","UD-CG 115 BS","COC1=CC=C(C=C1)C2=NC3=CC(=CC=C3[NH]2)C4=NNC(=O)CC4C",2.936,4,2,3]
["S1565","Lumacaftor (VX-809)","e5","L8000-03","in 10mM DMSO","CFTR","Transmembrane Transporters","Lumacaftor (VX-809, VRT 826809) acts to correct CFTR mutations common in cystic fibrosis by increasing mutant CFTR (F508del-CFTR) maturation,EC50 of 0.1 μM in fisher rat thyroid cells. Phase 3.",452.41,"936727-05-8",{"v":90,"d":"90.00"},198.93,"<1","N/A","http://selleckchem.com/products/VX-809.html","C24H18F2N2O5","free base","VRT 826809","CC1=C(N=C(NC(=O)C2(CC2)C3=CC4=C(OC(F)(F)O4)C=C3)C=C1)C5=CC=CC(=C5)C(O)=O",6.411,5,1,5]
["S1567","Pomalidomide (CC-4047)","f5","L8000-03","in 10mM DMSO","Apoptosis related,E3 Ligase ,E3 ligase Ligand,TNF-alpha","Ubiquitin","Pomalidomide (CC-4047) inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs. Pomalidomide can be utilized in PROTAC as a ligand for targeting E3 ligase and inhibiting the E3 ligase protein cereblon (CRBN). Pomalidomide promotes apoptosis and cell cycle arrest.",273.24,"19171-19-8",{"v":54,"d":"54.00"},197.63,"<1","N/A","http://selleckchem.com/products/Pomalidomide(CC-4047).html","C13H11N3O4","free base","CC-4047","NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1",{"v":-0.65,"d":"-0.650"},4,2,1]
["S1569","Tazarotene","g5","L8000-03","in 10mM DMSO","Retinoid Receptor","Metabolism","Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin.",351.46,"118292-40-3",{"v":10,"d":"10.00"},28.45,"<1","N/A","http://selleckchem.com/products/Tazarotene(Avage).html","C21H21NO2S","free base","AGN190168","CCOC(=O)C1=CN=C(C=C1)C#CC2=CC3=C(SCCC3(C)C)C=C2",4.951,3,0,5]
["S1573","Fasudil (HA-1077) HCl","h5","L8000-03","in 10mM DMSO","Autophagy,Calcium Channel,MLCK,PKA,PKC,PKG,Rho,ROCK","Cell Cycle","Fasudil (HA-1077, AT-877), a potent and selective inhibitor of Rho kinase, displays less potent inhibiton over PKA, PKG, PKC and MLCK with Ki of 1.6, 1.6, 3.3, and 36 μM in cell-free assays, respectively. Fasudil is also a calcium channel blocker.",327.83,"105628-07-7",{"v":5,"d":"5.00"},15.25,{"v":65,"d":"65.00"},198.27,"http://selleckchem.com/products/Fasudil-HCl(HA-1077).html","C14H17N3O2S.HCl","Hydrochloride","AT-877,HA-1077 HCl","Cl.O=[S](=O)(N1CCCNCC1)C2=C3C=CN=CC3=CC=C2",{"v":0.57,"d":"0.570"},3,1,2]
["S1576","Sulfasalazine (NSC 667219)","a6","L8000-03","in 10mM DMSO","Apoptosis related,Autophagy,COX,Ferroptosis,Immunology & Inflammation related,NF-κB,TGF-beta/Smad","Immunology & Inflammation","Sulfasalazine (NSC 667219, Azulfidine, Salazopyrin, Sulphasalazine) is a sulfa derivative of mesalazine, used as an anti-inflammatory agent to treat bowel disease and rheumatoid arthritis. Sulfasalazine is a potent and specific inhibitor of nuclear factor kappa B (NF-κB), TGF-β and COX-2. Sulfasalazine induces ferroptosis, apoptosis and autophagy.",398.39,"599-79-1",{"v":80,"d":"80.00"},200.81,"<1","N/A","http://selleckchem.com/products/Sulfasalazine(Azulfidine).html","C18H14N4O5S","free base","Azulfidine, Salazopyrin, Sulphasalazine, NSC 667219","OC(=O)C1=C(O)C=CC(=C1)N=NC2=CC=C(C=C2)[S](=O)(=O)NC3=CC=CC=N3",3.463,6,2,6]
["S1578","Candesartan (CV-11974)","b6","L8000-03","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Candesartan (CV-11974) is an angiotensin II receptor antagonist with IC50 of 0.26 nM.",440.45,"139481-59-7",{"v":88,"d":"88.00"},{"v":199.8,"d":"199.80"},"<1","N/A","http://selleckchem.com/products/Candesartan(Atacand).html","C24H20N6O3","free base","CV-11974","CCOC1=NC2=C([N]1CC3=CC=C(C=C3)C4=CC=CC=C4C5=N[NH]N=N5)C(=CC=C2)C(O)=O",4.626,6,1,7]
["S1591","Bestatin (NK421)","c6","L8000-03","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Bestatin (Ubenimex,NK421) is a potent aminopeptidase-B and leukotriene (LT) A4 hydrolase inhibitor, used in the treatment of acute myelocytic leukemia.",308.37,"58970-76-6",{"v":4,"d":"4.00"},12.97,"<1","N/A","http://www.selleck.cn/products/Ubenimex(Bestatin).html","C16H24N2O4","Free Base","Ubenimex,NK421","CC(C)CC(NC(=O)C(O)C(N)CC1=CC=CC=C1)C(O)=O",{"v":-1.34,"d":"-1.340"},2,3,8]
["S1593","Apixaban (BMS 562247-01)","d6","L8000-03","in 10mM DMSO","Factor Xa","Metabolism","Apixaban (BMS 562247-01) is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively.",{"v":459.5,"d":"459.50"},"503612-47-3",{"v":18,"d":"18.00"},39.17,"<1","N/A","http://selleckchem.com/products/Apixaban(BMS-562247-01).html","C25H25N5O4","free base","BMS 562247-01","COC1=CC=C(C=C1)[N]2N=C(C(N)=O)C3=C2C(=O)N(CC3)C4=CC=C(C=C4)N5CCCCC5=O",2.865,5,1,5]
["S1601","Reserpine","e6","L8000-03","in 10mM DMSO","VMAT","Transmembrane Transporters","Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug. Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).",608.68,"50-55-5",{"v":13,"d":"13.00"},21.36,"<1","N/A","http://selleckchem.com/products/Reserpine.html","C33H40N2O9","free base","N/A","COC1C(CC2CN3CCC4=C([NH]C5=C4C=CC(=C5)OC)C3CC2C1C(=O)OC)OC(=O)C6=CC(=C(OC)C(=C6)OC)OC",4.242,9,1,10]
["S1603","Furosemide (NSC 269420)","f6","L8000-03","in 10mM DMSO","NKCC","Transmembrane Transporters","Furosemide (NSC 269420) is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used in the treatment of congestive heart failure and edema.",330.74,"54-31-9",{"v":66,"d":"66.00"},199.55,"<1","N/A","http://selleckchem.com/products/Furosemide(Lasix).html","C12H11ClN2O5S","free base","NSC 269420","N[S](=O)(=O)C1=C(Cl)C=C(NCC2=CC=CO2)C(=C1)C(O)=O",1.403,4,2,5]
["S1604","Olmesartan Medoxomil","g6","L8000-03","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Olmesartan Medoxomil (CS-866,RNH-6270) is a selective angiotensin II type 1 (AT(1)) receptor antagonist, used in the treatment of high blood pressure.",558.59,"144689-63-4",{"v":89,"d":"89.00"},159.33,"<1","N/A","http://selleckchem.com/products/olmesartan-medoxomil-Benicar.html","C29H30N6O6","free base","CS-866,RNH-6270","CCCC1=NC(=C([N]1CC2=CC=C(C=C2)C3=CC=CC=C3C4=N[NH]N=N4)C(=O)OCC5=C(C)OC(=O)O5)C(C)(C)O",4.814,9,1,11]
["S1605","Cefdinir","h6","L8000-03","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Cefdinir (FK 482, PD 134393, CI-983) is an oral cephalosporin antibiotic, used to treat bacterial infections in many different parts of the body.",395.41,"91832-40-5",{"v":79,"d":"79.00"},199.79,"<1","N/A","http://selleckchem.com/products/Cefdinir(Omnicef).html","C14H13N5O5S2","free base","FK 482, PD 134393, CI-983","NC1=NC(=CS1)C(=N/O)/C(=O)NC2C3SCC(=C(N3C2=O)C(O)=O)C=C",-0.172,5,2,5]
["S1606","Clotrimazole","a7","L8000-03","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,Fungal","Microbiology","Clotrimazole (BAY b 5097, FB 5097) alters the permeability of the fungal cell wall by inhibiting the biosynthesis of ergosterol, used in the treatment of fungal infections.",344.84,"23593-75-1",{"v":11,"d":"11.00"},{"v":31.9,"d":"31.90"},"<1","N/A","http://selleckchem.com/products/Clotrimazole(Canesten).html","C22H17ClN2","free base","BAY b 5097, FB 5097","ClC1=C(C=CC=C1)C([N]2C=CN=C2)(C3=CC=CC=C3)C4=CC=CC=C4",5.222,1,0,4]
["S1607","Rizatriptan Benzoate","b7","L8000-03","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Rizatriptan Benzoate (MK-462) is an agonist at serotonin 5-HT1B and 5-HT1D receptors, used to treat acute migraine attacks.",391.47,"145202-66-0",{"v":20,"d":"20.00"},51.09,{"v":46,"d":"46.00"},117.51,"http://selleckchem.com/products/Rizatriptan-Benzoate(Maxalt).html","C22H25N5O2","Benzoate","MK-462 Benzoate","CN(C)CCC1=C[NH]C2=C1C=C(C[N]3C=NC=N3)C=C2.OC(=O)C4=CC=CC=C4",0.492,3,1,6]
["S1608","Pyridostigmine Bromide","c7","L8000-03","in 10mM DMSO","AChR","Neuronal Signaling","Pyridostigmine Bromide is a parasympathomimetic and a reversible cholinesterase inhibitor.",261.12,"101-26-8",{"v":52,"d":"52.00"},199.14,{"v":52,"d":"52.00"},199.14,"http://selleckchem.com/products/Pyridostigmine-Bromide(Mestinon).html","C9H13BrN2O2","Bromide","N/A","[Br-].CN(C)C(=O)OC1=C[N+](=CC=C1)C",-1.014,2,0,2]
["S1613","Silodosin","d7","L8000-03","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Silodosin (KAD 3213, KMD 3213) is a highly selective α1A-adrenoceptor antagonist, used in treatment of benign prostatic hyperplasia.",495.53,"160970-54-7",{"v":99,"d":"99.00"},199.79,"<1","N/A","http://selleckchem.com/products/Silodosin(Rapaflo).html","C25H32F3N3O4","free base","KAD 3213, KMD 3213","CC(CC1=CC2=C(N(CCCO)CC2)C(=C1)C(N)=O)NCCOC3=CC=CC=C3OCC(F)(F)F",3.451,3,3,14]
["S1614","Riluzole (PK 26124)","e7","L8000-03","in 10mM DMSO","GluR,Sodium Channel","Transmembrane Transporters","Riluzole (PK 26124, RP-54274) is a glutamate release inhibitor with neuroprotective, anticonvulsant, anxiolytic and anesthetic qualities.",{"v":234.2,"d":"234.20"},"1744-22-5",{"v":46,"d":"46.00"},196.41,"<1","N/A","http://selleckchem.com/products/Riluzole(Rilutek).html","C8H5F3N2OS","free base","RP-54274, PK 26124","NC1=NC2=C(S1)C=C(OC(F)(F)F)C=C2",3.828,2,1,2]
["S1618","Sulfameter","f7","L8000-03","in 10mM DMSO","Bacterial","Immunology & Inflammation","Sulfameter  is a long-acting sulfonamide antibacterial.",{"v":280.3,"d":"280.30"},"651-06-9",{"v":56,"d":"56.00"},199.79,"<1","N/A","http://selleckchem.com/products/Sulfameter(Bayrena).html","C11H12N4O3S","free base","N/A","COC1=CN=C(N[S](=O)(=O)C2=CC=C(N)C=C2)N=C1",0.297,5,2,4]
["S1622","Prednisone (NSC-10023)","g7","L8000-03","in 10mM DMSO","Glucocorticoid Receptor,Immunology & Inflammation related","Endocrinology & Hormones","Prednisone (NSC-10023, Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.",358.43,"53-03-2",{"v":71,"d":"71.00"},198.09,"<1","N/A","http://selleckchem.com/products/Prednisone.html","C21H26O5","free base","Adasone,NSC-10023","CC12CC(=O)C3C(CCC4=CC(=O)C=CC34C)C1CCC2(O)C(=O)CO",1.217,3,1,2]
["S1625","Ethinyl Estradiol","a8","L8000-03","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Ethinyl Estradiol is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills.",{"v":296.4,"d":"296.40"},"57-63-6",{"v":59,"d":"59.00"},199.06,"<1","N/A","http://selleckchem.com/products/Ethinyl-Estradiol.html","C20H24O2","free base","N/A","CC12CCC3C(CCC4=CC(=CC=C34)O)C1CCC2(O)C#C",4.886,0,1,0]
["S1626","Naproxen Sodium","b8","L8000-03","in 10mM DMSO","COX","Neuronal Signaling","Naproxen Sodium (RS-3650) is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively.",252.24,"26159-34-2",{"v":3,"d":"3.00"},11.89,{"v":50,"d":"50.00"},198.22,"http://selleckchem.com/products/Naproxen-Sodium(Aleve).html","C14H13NaO3","Sodium Salt","RS-3650","[Na+].COC1=CC=C2C=C(C=CC2=C1)C(C)C([O-])=O",1.375,1,0,3]
["S1627","Nitazoxanide (NSC 697855)","c8","L8000-03","in 10mM DMSO","Autophagy,Influenza Virus,mTOR,Serotonin Transporter","Microbiology","Nitazoxanide (NTZ, NSC 697855) is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent(IC50 for canine influenza virus ranges from 0.17 to 0.21 μM). Nitazoxanide modulates autophagy and inhibits mTORC1 signaling.",307.28,"55981-09-4",{"v":62,"d":"62.00"},201.77,"<1","N/A","http://selleckchem.com/products/Nitazoxanide(Alinia).html","C12H9N3O5S","free base","NTZ, NSC 697855","CC(=O)OC1=C(C=CC=C1)C(=O)NC2=NC=C(S2)[N+]([O-])=O",1.398,4,1,5]
["S1628","Triamcinolone Acetonide","d8","L8000-03","in 10mM DMSO","Glucocorticoid Receptor","Metabolism","Triamcinolone acetonide is a synthetic glucocorticoid, used in the symptomatic treatment of inflammation.",{"v":434.5,"d":"434.50"},"76-25-5",{"v":87,"d":"87.00"},200.23,"<1","N/A","http://selleckchem.com/products/Triamcinolone-Acetonide.html","C24H31FO6","free base","N/A","CC1(C)OC2CC3C4CCC5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(O1)C(=O)CO",1.157,4,2,2]
["S1629","Orlistat (Ro 18-0647)","e8","L8000-03","in 10mM DMSO","Apoptosis related,Fatty Acid Synthase,Lipase","Metabolism","Orlistat (Ro 18-0647, Tetrahydrolipstatin) is a general lipase inhibitor with IC50 of 122 ng/ml for PL from human duodenal juice. Orlistat treatment reduces proliferation, induces apoptosis and arrests cell cycle.",495.73,"96829-58-2",{"v":99,"d":"99.00"},199.71,"<1","N/A","http://selleckchem.com/products/Orlistat(Alli).html","C29H53NO5","free base","Tetrahydrolipstatin,Ro 18-0647","CCCCCCCCCCCC(CC1OC(=O)C1CCCCCC)OC(=O)C(CC(C)C)NC=O",8.333,5,1,23]
["S1630","Allopurinol","f8","L8000-03","in 10mM DMSO","ROS","Immunology & Inflammation","Allopurinol is a purine analog inhibitor of the enzyme xanthine oxidase, used to treat gout or kidney stones, and to decrease levels of uric acid.",136.11,"315-30-0",{"v":27,"d":"27.00"},198.37,{"v":4,"d":"4.00"},29.39,"http://selleckchem.com/products/Allopurinol(Zyloprim).html","C5H4N4O","Free Base","N/A","O=C1N=CN=C2NNC=C12",-2.125,3,2,0]
["S1631","Allopurinol Sodium","g8","L8000-03","in 10mM DMSO","ROS","Immunology & Inflammation","Allopurinol Sodium  is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.",{"v":159.1,"d":"159.10"},"17795-21-0",{"v":32,"d":"32.00"},201.13,{"v":32,"d":"32.00"},201.13,"http://selleckchem.com/products/Allopurinol-Sodium(Aloprim).html","C5H4N4NaO","Sodium Salt","N/A","[Na+].O=C1NC=NC2=C1C=N[NH]2",-0.681,3,2,0]
["S1633","Zafirlukast (ICI-204219)","h8","L8000-03","in 10mM DMSO","LTR","Immunology & Inflammation","Zafirlukast (ICI-204219) is an oral leukotriene receptor antagonist (LTRA), used to prevent asthma symptoms.",575.68,"107753-78-6",{"v":100,"d":"100.00"},173.71,"<1","N/A","http://selleckchem.com/products/Zafirlukast(Accolate).html","C31H33N3O6S","free base","ICI-204219","COC1=CC(=CC=C1CC2=C[N](C)C3=C2C=C(NC(=O)OC4CCCC4)C=C3)C(=O)N[S](=O)(=O)C5=CC=CC=C5C",6.299,6,2,9]
["S1635","Erythromycin","a9","L8000-03","in 10mM DMSO","Antibiotics,Antibiotics for Mammalian Cell Culture","Microbiology","Erythromycin (E-Mycin) is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin (IC50=1.5 μg/ml).",733.93,"114-07-8",{"v":147,"d":"147.00"},200.29,{"v":3,"d":"3.00"},4.09,"http://selleckchem.com/products/Erythromycin(E-Mycin).html","C37H67NO13","Free Base","E-Mycin","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)C(=O)C(C)C(O)C1(C)O",1.792,8,3,7]
["S1638","Ibuprofen (NSC 256857)","b9","L8000-03","in 10mM DMSO","COX","Neuronal Signaling","Ibuprofen (NSC 256857, Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively.",206.28,"15687-27-1",{"v":41,"d":"41.00"},198.76,"<1","N/A","http://selleckchem.com/products/Ibuprofen(Advil).html","C13H18O2","free base","Dolgesic,NSC 256857","CC(C)CC1=CC=C(C=C1)C(C)C(O)=O",3.607,1,0,4]
["S1639","Amprenavir (VX-478)","c9","L8000-03","in 10mM DMSO","HIV Protease","Proteases","Amprenavir (VX-478, 141W94, KVX-478) is a potent PXR-selective agonist, and an HIV protease inhibitor, used to treat HIV.",505.63,"161814-49-9",{"v":16,"d":"16.00"},31.64,"<1","N/A","http://selleckchem.com/products/Amprenavir-(Agenerase).html","C25H35N3O6S","free base","141W94, VX-478, KVX-478","CC(C)CN(CC(O)C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)[S](=O)(=O)C3=CC=C(N)C=C3",2.429,5,3,12]
["S1640","Albendazole (SKF-62979)","d9","L8000-03","in 10mM DMSO","ADC Cytotoxin,Microtubule Associated","Cytoskeletal Signaling","Albendazole (SKF-62979) is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.",265.33,"54965-21-8",{"v":17,"d":"17.00"},64.07,"<1","N/A","http://selleckchem.com/products/Albendazole(Albenza).html","C12H15N3O2S","free base","SKF-62979","CCCSC1=CC=C2N=C(NC(=O)OC)[NH]C2=C1",3.065,3,2,5]
["S1641","Chlorothiazide","e9","L8000-03","in 10mM DMSO","Others","Others","Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM)",295.72,"58-94-6",{"v":59,"d":"59.00"},199.51,"<1","N/A","http://selleckchem.com/products/Chlorothiazide(Diuril).html","C7H6ClN3O4S2","free base","N/A","N[S](=O)(=O)C1=C(Cl)C=C2N=CN[S](=O)(=O)C2=C1",-0.177,5,2,1]
["S1643","Ursodiol","f9","L8000-03","in 10mM DMSO","FXR","GPCR & G Protein","Ursodiol (Ursodeoxycholic acid, UDCA) reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones. (IC50=0.22 μM)",392.57,"128-13-2",{"v":79,"d":"79.00"},201.24,"<1","N/A","http://selleckchem.com/products/Ursodiol(Actigal).html","C24H40O4","free base","Ursodeoxycholic acid, UDCA","CC(CCC(O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C",4.014,1,2,4]
["S1644","Nitrofural","g9","L8000-03","in 10mM DMSO","Anti-infection","Microbiology","Nitrofural (Nitrofurazone) is a topical anti-infective agent with an IC50 of 22.83 ± 1.2 μM. (Rat LD50 = 590 mg/kg)",198.14,"59-87-0",{"v":40,"d":"40.00"},201.88,"<1","N/A","http://selleckchem.com/products/Nitrofurazone(ACTIN-N).html","C6H6N4O4","free base","Nitrofurazone","NC(=O)N/N=C/C1=CC=C(O1)[N+]([O-])=O",0.223,3,2,3]
["S1645","Ketoprofen","h9","L8000-03","in 10mM DMSO","COX","Neuronal Signaling","Ketoprofen (RP-19583) is a dual COX1/2 inhibitor, used as a nonsteroidal anti-inflammatory drug to treat arthritis-related inflammatory pains.",254.28,"22071-15-4",{"v":51,"d":"51.00"},200.57,"<1","N/A","http://selleckchem.com/products/Ketoprofen(Actron).html","C16H14O3","free base","RP-19583","CC(C(O)=O)C1=CC(=CC=C1)C(=O)C2=CC=CC=C2",3.361,2,0,4]
["S1647","Adenosine","a10","L8000-03","in 10mM DMSO","Adenosine Receptor,Nucleoside Analog/Antimetabolite","GPCR & G Protein","Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond.",267.24,"58-61-7",{"v":12,"d":"12.00"},{"v":44.9,"d":"44.90"},"<1","N/A","http://selleckchem.com/products/Adenosine(Adenocard).html","C10H13N5O4","free base","N/A","NC1=NC=NC2=C1N=C[N]2C3OC(CO)C(O)C3O",-1.881,4,4,2]
["S1649","Zolmitriptan","b10","L8000-03","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Zolmitriptan(BW-311C90) is a novel and highly selective 5-HT(1B/1D) receptor agonist, used in the treatment of acute migraines.",287.36,"139264-17-8",{"v":58,"d":"58.00"},201.84,"<1","N/A","http://selleckchem.com/products/Zolmitriptan(Zomig).html","C16H21N3O2","free base","BW-311C90","CN(C)CCC1=C[NH]C2=C1C=C(CC3COC(=O)N3)C=C2",2.457,2,2,5]
["S1651","Telbivudine","c10","L8000-03","in 10mM DMSO","Reverse Transcriptase","Microbiology","Telbivudine(NV 02B) is a potent, and selective HBV reverse transcriptase inhibitor, used to treat HBV infection.",242.23,"3424-98-4",{"v":48,"d":"48.00"},198.16,{"v":48,"d":"48.00"},198.16,"http://selleckchem.com/products/Telbivudine(Sebivo).html","C10H14N2O5","free base","NV 02B","CC1=CN(C2CC(O)C(CO)O2)C(=O)NC1=O",-1.238,3,3,2]
["S1652","Monobenzone","d10","L8000-03","in 10mM DMSO","Tyrosinase","Proteases","Monobenzone(Benoquin) is a compound used as a topical agent for medical depigmentation. It can specifically block tyrosinase.",200.23,"103-16-2",{"v":40,"d":"40.00"},199.77,"<1","N/A","http://selleckchem.com/products/Monobenzone(Benoquin).html","C13H12O2","free base","Benoquin","OC1=CC=C(OCC2=CC=CC=C2)C=C1",3.155,1,1,3]
["S1653","Tretinoin (NSC 122758)","e10","L8000-03","in 10mM DMSO","Retinoid Receptor","Metabolism","Tretinoin (Retinoic acid, All-trans Retinoic Acid, ATRA, Vitamin A acid, Vesanoid, Airol, Renova, Atralin, Retin-A, Avita, Stieva-A,NSC 122758), which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.",{"v":300.4,"d":"300.40"},"302-79-4",{"v":60,"d":"60.00"},199.73,"<1","N/A","http://selleckchem.com/products/Tretinoin(Aberela).html","C20H28O2","free base","Retinoic acid, All-trans Retinoic Acid, ATRA, Vitamin A acid, Vesanoid, Airol, Renova, Atralin, Retin-A, Avita, Stieva-A,NSC 122758","CC1=C(\\C=C\\C(C)=C\\C=C\\C(C)=C\\C(O)=O)C(C)(C)CCC1",5.551,1,0,5]
["S1654","Phenylbutazone","f10","L8000-03","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Phenylbutazone (Butazolidine) is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis.",308.37,"50-33-9",{"v":62,"d":"62.00"},201.06,"<1","N/A","http://selleckchem.com/products/Phenylbutazone(Butazolidin).html","C19H20N2O2","free base","Butazolidine","CCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3",3.954,2,0,5]
["S1655","Ezetimibe (SCH-58235)","g10","L8000-03","in 10mM DMSO","LDL","Metabolism","Ezetimibe (SCH-58235) is a potent, selective, cholesterol absorption inhibitor, used to lower cholesterol.",{"v":409.4,"d":"409.40"},"163222-33-1",{"v":81,"d":"81.00"},197.85,"<1","N/A","http://selleckchem.com/products/Ezetimibe(Zetia).html","C24H21F2NO3","free base","SCH-58235","OC(CCC1C(N(C1=O)C2=CC=C(F)C=C2)C3=CC=C(O)C=C3)C4=CC=C(F)C=C4",4.633,1,2,6]
["S1658","Dofetilide","h10","L8000-03","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Dofetilide (UK-68798) is a selective potassium channel ((hERG)) blocker, used as a Class III antiarrhythmic drug.",441.56,"115256-11-6",{"v":88,"d":"88.00"},199.29,"<1","N/A","http://selleckchem.com/products/Dofetilide(Tikosyn).html","C19H27N3O5S2","free base","UK-68798","CN(CCOC1=CC=C(N[S](C)(=O)=O)C=C1)CCC2=CC=C(N[S](C)(=O)=O)C=C2",1.679,5,2,11]
["S1665","Estrone","a11","L8000-03","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estrone is an estrogenic hormone.",270.37,"53-16-7",{"v":54,"d":"54.00"},199.73,"<1","N/A","http://selleckchem.com/products/Estrone.html","C18H22O2","free base","N/A","CC12CCC3C(CCC4=CC(=CC=C34)O)C1CCC2=O",3.938,1,1,0]
["S1666","Flucytosine","b11","L8000-03","in 10mM DMSO","Fungal","Microbiology","Flucytosine (5-Fluorocytosine, 5-FC, NSC 103805, Ro 2-9915) is an antifungal drug with IC50 of 0.93 μM in C. albicans.",129.09,"2022-85-7",{"v":8,"d":"8.00"},61.97,{"v":5,"d":"5.00"},38.73,"http://selleckchem.com/products/Flucytosine(Ancobon).html","C4H4FN3O","free base","5-Fluorocytosine, 5-FC, NSC 103805, Ro 2-9915","NC1=NC(=O)NC=C1F",-1.048,2,2,0]
["S1667","Trichlormethiazide","c11","L8000-03","in 10mM DMSO","Others","Others","Trichlormethiazide is a diuretic with properties similar to those of hydrochlorothiazide.",380.66,"133-67-5",{"v":54,"d":"54.00"},141.86,"<1","N/A","http://selleckchem.com/products/Trichlormethiazide(Achletin).html","C8H8Cl3N3O4S2","free base","N/A","N[S](=O)(=O)C1=C(Cl)C=C2NC(N[S](=O)(=O)C2=C1)C(Cl)Cl",1.046,4,3,2]
["S1679","Flurbiprofen","e11","L8000-03","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs).",244.26,"5104-49-4",{"v":49,"d":"49.00"},200.61,"<1","N/A","http://selleckchem.com/products/Flurbiprofen(Ansaid).html","C15H13FO2","free base","N/A","CC(C(O)=O)C1=CC(=C(C=C1)C2=CC=CC=C2)F",{"v":3.68,"d":"3.680"},1,0,3]
["S1680","Disulfiram (NSC 190940)","f11","L8000-03","in 10mM DMSO","Apoptosis related,COVID-19,Dehydrogenase,Pyroptosis","Metabolism","Disulfiram (NSC 190940, Tetraethylthiuram disulfide, TETD) is a specific inhibitor of aldehyde-dehydrogenase (ALDH) with IC50 of 0.15 μM and 1.45 μM for hALDH1 and hALDH2, respectively. Disulfiram is used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram induces apoptosis. Disulfiram is also an inhibitor of pore formation by gasdermin D (GSDMD).",296.54,"97-77-8",{"v":59,"d":"59.00"},198.96,"<1","N/A","http://selleckchem.com/products/Disulfiram(Antabuse).html","C10H20N2S4","free base","NSC 190940, Tetraethylthiuram disulfide, TETD","CCN(CC)C(=S)SSC(=S)N(CC)CC",{"v":5.6,"d":"5.600"},0,0,9]
["S1681","Mesalamine (5-ASA)","g11","L8000-03","in 10mM DMSO","Immunology & Inflammation related,IκB/IKK","NF-κB","Mesalamine (5-Aminosalicylic acid, 5-ASA, Mesalazine, Apriso, Asacol, Pentasa, Canasa) is a specific inhibitor of TNFα-induced IKK activity, used to treat inflammatory bowel disease.",153.14,"89-57-6",{"v":31,"d":"31.00"},202.43,"<1","N/A","http://selleckchem.com/products/Mesalamine(Lialda).html","C7H7NO3","free base","5-Aminosalicylic acid, 5-ASA, Mesalazine, Apriso, Asacol, Pentasa, Canasa","NC1=CC=C(O)C(=C1)C(O)=O",0.471,1,2,1]
["S1683","Ipratropium Bromide","h11","L8000-03","in 10mM DMSO","AChR","Neuronal Signaling","Ipratropium Bromide is an antagonist of M3 type muscarinic acetylcholine receptors, used for the treatment of chronic obstructive pulmonary disease (COPD).",412.37,"22254-24-6",{"v":83,"d":"83.00"},201.28,{"v":83,"d":"83.00"},201.28,"http://selleckchem.com/products/Ipratropium-bromide.html","C20H30BrNO3","Bromide","N/A","[Br-].CC(C)[N+]1(C)C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",-1.326,2,1,6]
["S1685","Sulfanilamide","a2","L8000-04","in 10mM DMSO","Bacterial","Microbiology","Sulfanilamide (Sulphanilamide) is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.",{"v":172.2,"d":"172.20"},"63-74-1",{"v":34,"d":"34.00"},197.44,"<1","N/A","http://selleckchem.com/products/Sulfanilamide.html","C6H8N2O2S","free base","N/A","NC1=CC=C(C=C1)[S](N)(=O)=O",-0.212,2,2,1]
["S1688","Betamethasone Dipropionate","b2","L8000-04","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Betamethasone Dipropionate (SCH 11460) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.",504.59,"5593-20-4",{"v":100,"d":"100.00"},198.18,"<1","N/A","http://selleckchem.com/products/Betamethasone-Dipropionate(Diprolene).html","C28H37FO7","Free Base","SCH 11460","CCC(=O)OCC(=O)C1(OC(=O)CC)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C",{"v":3.8,"d":"3.800"},6,1,8]
["S1689","Meprednisone","c2","L8000-04","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Meprednisone (NSC 527579, SCH 4358) is a glucocorticoid and a methylated derivative of prednisone.",372.46,"1247-42-3",{"v":75,"d":"75.00"},201.37,"<1","N/A","http://selleckchem.com/products/Betapar(Meprednisone).html","C22H28O5","free base","NSC 527579, SCH 4358","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3C(=O)CC2(C)C1(O)C(=O)CO",1.536,3,1,2]
["S1690","Betamethasone Valerate","d2","L8000-04","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Betamethasone Valerate is a moderately potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.",476.58,"2152-44-5",{"v":95,"d":"95.00"},199.34,"<1","N/A","http://selleckchem.com/products/Betamethasone-valerate(Betnovate).html","C27H37FO6","free base","N/A","CCCCC(=O)OC1(C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)CO",3.666,4,2,7]
["S1692","Busulfan (NSC-750)","e2","L8000-04","in 10mM DMSO","Apoptosis related,DNA alkylator","DNA Damage/DNA Repair","Busulfan (NSC-750) is a cell cycle non-specific alkylating antineoplastic agent. Busulfan induces apoptosis.",{"v":246.3,"d":"246.30"},"55-98-1",{"v":49,"d":"49.00"},198.94,"<1","N/A","http://selleckchem.com/products/Busulfan(Busulfex).html","C6H14O6S2","free base","NSC-750","C[S](=O)(=O)OCCCCO[S](C)(=O)=O",-0.289,2,0,7]
["S1693","Carbamazepine","f2","L8000-04","in 10mM DMSO","Autophagy,Sodium Channel","Transmembrane Transporters","Carbamazepine (Carbatrol, NSC 169864) is a sodium channel blocker with IC50 of 131 μM in rat brain synaptosomes.",236.27,"298-46-4",{"v":47,"d":"47.00"},198.92,"<1","N/A","http://selleckchem.com/products/Carbamazepine(Carbatrol).html","C15H12N2O","free base","NSC 169864","NC(=O)N1C2=C(C=CC=C2)C=CC3=C1C=CC=C3",2.679,1,1,0]
["S1696","Hydrocortisone (NSC 10483)","g2","L8000-04","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Hydrocortisone (NSC 10483, Cortisol) is a steroid hormone or glucocorticoid produced by the adrenal gland.",362.46,"50-23-7",{"v":73,"d":"73.00"},{"v":201.4,"d":"201.40"},"<1","N/A","http://selleckchem.com/products/Hydrocortisone.html","C21H30O5","free base","Cortisol","CC12CCC(=O)C=C1CCC3C4CCC(O)(C(=O)CO)C4(C)CC(O)C23",1.283,2,2,2]
["S1701","Desonide","h2","L8000-04","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Desonide is a low potency topical corticosteroid.",416.51,"638-94-8",{"v":83,"d":"83.00"},199.27,"<1","N/A","http://selleckchem.com/products/Desonide.html","C24H32O6","free base","N/A","CC1(C)OC2CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC3(C)C2(O1)C(=O)CO",1.028,4,2,2]
["S1702","Didanosine","a3","L8000-04","in 10mM DMSO","Reverse Transcriptase","Microbiology","Didanosine is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.",236.23,"69655-05-6",{"v":47,"d":"47.00"},198.96,"<1","N/A","http://selleckchem.com/products/Didanosine(Videx).html","C10H12N4O3","free base","N/A","OCC1CCC(O1)[N]2C=NC3=C2N=CNC3=O",-0.844,4,2,2]
["S1705","Progesterone (NSC 9704)","b3","L8000-04","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Progesterone (NSC 9704, NSC 64377, Pregn-4-ene-3,20-dione) is an endogenous steroid hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. A potent agonist of the nuclear progesterone receptor (nPR) with Kd of 1 nM; An agonist of the membrane progesterone receptors(mPRs); An antagonist of the σ1 receptor.",314.46,"57-83-0",{"v":22,"d":"22.00"},69.96,"<1","N/A","http://selleckchem.com/products/Progesterone(Prometrium).html","C21H30O2","free base","NSC 64377, Pregn-4-ene-3,20-dione,NSC 9704","CC(=O)C1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C",{"v":3.86,"d":"3.860"},2,0,1]
["S1706","Lamivudine (BCH-189)","c3","L8000-04","in 10mM DMSO","COVID-19,Reverse Transcriptase","Microbiology","Lamivudine (BCH-189, GR109714X) is a potent nucleoside analog reverse transcriptase inhibitor, used for treatment of chronic HBV and HIV/AIDS. It works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase.",229.26,"134678-17-4",{"v":46,"d":"46.00"},200.65,{"v":46,"d":"46.00"},200.65,"http://selleckchem.com/products/Lamivudine(Epivir).html","C8H11N3O3S","free base","GR109714X, BCH-189","NC1=NC(=O)N(C=C1)C2CSC(CO)O2",{"v":-0.59,"d":"-0.590"},3,2,2]
["S1709","Estradiol","d3","L8000-04","in 10mM DMSO","Estrogen/progestogen Receptor,Interleukins","Endocrinology & Hormones","Estradiol (17β-estradiol, β-Estradiol, E2, 17β-Oestradiol) is a human sex hormone and steroid, and the primary female sex hormone. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.",272.38,"50-28-2",{"v":54,"d":"54.00"},198.25,"<1","N/A","http://selleckchem.com/products/Estradiol.html","C18H24O2","free base","17β-estradiol, β-Estradiol, E2, 17β-Oestradiol","CC12CCC3C(CCC4=C3C=CC(=C4)O)C1CCC2O",3.838,0,2,0]
["S1712","Deferasirox (ICL-670)","e3","L8000-04","in 10mM DMSO","Ferroptosis,P450 (e.g. CYP17)","Proteases","Deferasirox (ICL-670, CGP-72670) is an iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor. Deferasirox-induced iron depletion promotes BclxL downregulation and cell death.",373.36,"201530-41-8",{"v":74,"d":"74.00"},{"v":198.2,"d":"198.20"},"<1","N/A","http://selleckchem.com/products/Deferasirox(Exjade).html","C21H15N3O4","free base","CGP-72670, ICL-670","OC(=O)C1=CC=C(C=C1)[N]2N=C(N=C2C3=CC=CC=C3O)C4=CC=CC=C4O",4.063,3,2,4]
["S1713","Piroxicam","f3","L8000-04","in 10mM DMSO","COX","Neuronal Signaling","Piroxicam (CP 16171) is a non-selective COX inhibitor, used in the treatment of rheumatoid and osteoarthritis.",331.35,"36322-90-4",{"v":66,"d":"66.00"},199.19,"<1","N/A","http://selleckchem.com/products/Piroxicam(Feldene).html","C15H13N3O4S","free base","CP 16171","CN1C(=C(O)C2=C(C=CC=C2)[S]1(=O)=O)C(=O)NC3=NC=CC=C3",0.501,4,2,2]
["S1714","Gemcitabine (LY-188011)","g3","L8000-04","in 10mM DMSO","Apoptosis related,Autophagy,DNA/RNA Synthesis,Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Gemcitabine (LY-188011, NSC 613327), a nucleic acid synthesis inhibitor, is a very potent and specific deoxycytidine analogue, used as chemotherapy. Gemcitabine induces a potent p53-dependent apoptosis.",{"v":263.2,"d":"263.20"},"95058-81-4",{"v":52,"d":"52.00"},197.57,{"v":52,"d":"52.00"},197.57,"http://selleckchem.com/products/Gemcitabine(Gemzar).html","C9H11F2N3O4","Free Base","LY-188011, NSC 613327","NC1=NC(=O)N(C=C1)C2OC(CO)C(O)C2(F)F",-1.394,3,3,2]
["S1715","Glipizide","h3","L8000-04","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Glipizide (CP-28720,K 4024) is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes.",445.54,"29094-61-9",{"v":89,"d":"89.00"},199.76,"<1","N/A","http://selleckchem.com/products/Glipizide(Glucotrol).html","C21H27N5O4S","free base","CP-28720,K 4024","CC1=NC=C(N=C1)C(=O)NCCC2=CC=C(C=C2)[S](=O)(=O)NC(=O)NC3CCCCC3",1.902,6,3,7]
["S1718","Adefovir Dipivoxil (GS 0840)","a4","L8000-04","in 10mM DMSO","Reverse Transcriptase","Microbiology","Adefovir Dipivoxil (GS 0840) is a reverse transcriptase inhibitor, used in the treatment of chronic hepatitis B virus (HBV).",501.47,"142340-99-6",{"v":100,"d":"100.00"},199.41,"<1","N/A","http://selleckchem.com/products/Adefovir-Dipivoxil(Preveon).html","C20H32N5O8P","free base","GS 0840","CC(C)(C)C(=O)OCO[P](=O)(COCC[N]1C=NC2=C1N=CN=C2N)OCOC(=O)C(C)(C)C",1.666,10,1,15]
["S1721","Azathioprine","b4","L8000-04","in 10mM DMSO","Rho","Cell Cycle","Azathioprine(BW 57-322) is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases.",277.26,"446-86-6",{"v":54,"d":"54.00"},194.76,"<1","N/A","http://selleckchem.com/products/Azathioprine(Azasan).html","C9H7N7O2S","free base","BW 57-322","C[N]1C=NC(=C1SC2=C3[NH]C=NC3=NC=N2)[N+]([O-])=O",1.071,4,1,3]
["S1723","Indomethacin (NSC-77541)","c4","L8000-04","in 10mM DMSO","COX","Neuronal Signaling","Indomethacin (NSC-77541, Indometacin) is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively, used to reduce fever, pain, stiffness, and swelling.",357.79,"53-86-1",{"v":72,"d":"72.00"},201.24,"<1","N/A","http://selleckchem.com/products/Indomethacin(Indocid).html","C19H16ClNO4","free base","Indometacin,NSC-77541","COC1=CC=C2[N](C(=C(CC(O)=O)C2=C1)C)C(=O)C3=CC=C(Cl)C=C3",4.235,3,0,4]
["S1727","Levonorgestrel","d4","L8000-04","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Levonorgestrel (D-Norgestrel) is a female hormone that prevents ovulation.",312.45,"797-63-7",{"v":45,"d":"45.00"},144.02,"<1","N/A","http://selleckchem.com/products/Levonorgestrel(Levonelle).html","C21H28O2","free base","D-Norgestrel","CCC12CCC3C(CCC4=CC(=O)CCC34)C1CCC2(O)C#C",4.771,1,0,1]
["S1729","Gemfibrozil","e4","L8000-04","in 10mM DMSO","PPAR","Metabolism","Gemfibrozil (CI-719) is an activator of peroxisome proliferator-activated receptor-alpha (PPARα), used for the treatment of hypercholesterolemia and hypertriglyceridemia.",250.33,"25812-30-0",{"v":50,"d":"50.00"},199.74,"<1","N/A","http://selleckchem.com/products/Gemfibrozil(Lopid).html","C15H22O3","free base","CI-719","CC1=CC(=C(C)C=C1)OCCCC(C)(C)C(O)=O",4.172,2,0,6]
["S1730","Indapamide","f4","L8000-04","in 10mM DMSO","Others","Others","Indapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.",365.83,"26807-65-8",{"v":73,"d":"73.00"},199.55,"<1","N/A","http://selleckchem.com/products/Indapamide(Lozol).html","C16H16ClN3O3S","free base","N/A","CC1CC2=C(C=CC=C2)N1NC(=O)C3=CC=C(Cl)C(=C3)[S](N)(=O)=O",2.664,3,2,3]
["S1732","Mitotane","g4","L8000-04","in 10mM DMSO","Others","Others","Mitotane (NCI-C04933), is an antineoplastic medication used in the treatment of adrenocortical carcinoma.",320.04,"53-19-0",{"v":64,"d":"64.00"},199.98,"<1","N/A","http://selleckchem.com/products/Mitotane(Lysodren).html","C14H10Cl4","free base","NCI-C04933","ClC(Cl)C(C1=CC=C(Cl)C=C1)C2=C(Cl)C=CC=C2",5.745,0,0,3]
["S1733","Methylprednisolone (NSC-19987)","h4","L8000-04","in 10mM DMSO","ACE,Apoptosis related,Autophagy,Glucocorticoid Receptor,Immunology & Inflammation related,Interleukins","Endocrinology & Hormones","Methylprednisolone (NSC-19987,U 7532) is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.",374.47,"83-43-2",{"v":75,"d":"75.00"},200.28,"<1","N/A","http://selleckchem.com/products/Methylprednisolone.html","C22H30O5","free base","NSC-19987,U 7532","CC1CC2C3CCC(O)(C(=O)CO)C3(C)CC(O)C2C4(C)C=CC(=O)C=C14",1.512,2,2,2]
["S1734","Meloxicam","a5","L8000-04","in 10mM DMSO","COX","Neuronal Signaling","Meloxicam is a selective COX inhibitor, used to relieve pain and fever effects.",{"v":351.4,"d":"351.40"},"71125-38-7",{"v":30,"d":"30.00"},85.37,"<1","N/A","http://selleckchem.com/products/Meloxicam(Mobic).html","C14H13N3O4S2","free base","N/A","CN1C(=C(O)C2=C(C=CC=C2)[S]1(=O)=O)C(=O)NC3=NC=C(C)S3",0.255,4,2,2]
["S1735","Mesna","b5","L8000-04","in 10mM DMSO","Others","Others","Mesna, a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents.",164.18,"19767-45-4",{"v":33,"d":"33.00"},{"v":201,"d":"201.00"},{"v":7,"d":"7.00"},42.64,"http://selleckchem.com/products/Mesna(Uromitexan).html","C2H5NaO3S2","Sodium Salt","N/A","[Na+].[O-][S](=O)(=O)CCS",-2.227,0,0,2]
["S1736","Methocarbamol","c5","L8000-04","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Methocarbamol (AHR 85) is a carbonic anhydrase inhibitor, used as a central muscle relaxant to treat skeletal muscle spasms.",241.24,"532-03-6",{"v":48,"d":"48.00"},198.97,{"v":2,"d":"2.00"},8.29,"http://selleckchem.com/products/Methocarbamol(Robaxin).html","C11H15NO5","free base","AHR 85","COC1=C(OCC(O)COC(N)=O)C=CC=C1",0.916,4,2,7]
["S1738","Telmisartan","d5","L8000-04","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Telmisartan (BIBR 277) is an angiotensin II receptor antagonist (ARB) used in the management of hypertension.",514.62,"144701-48-4",{"v":13,"d":"13.00"},25.26,"<1","N/A","http://selleckchem.com/products/Telmisartan(Micardis).html","C33H30N4O2","free base","BIBR 277","CCCC1=NC2=C(C=C(C=C2C)C3=NC4=C(C=CC=C4)[N]3C)[N]1CC5=CC=C(C=C5)C6=CC=CC=C6C(O)=O",7.799,3,0,7]
["S1739","Thiabendazole","e5","L8000-04","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Thiabendazole inhibits the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property, used as an anthelmintic and fungicide agent. It is a potent inhibitor of  cytochrome P450 1A2 (CYP1A2).",201.25,"148-79-8",{"v":40,"d":"40.00"},198.76,"<1","N/A","http://selleckchem.com/products/Thiabendazole.html","C10H7N3S","free base","N/A","[NH]1C2=C(C=CC=C2)N=C1C3=CSC=N3",2.154,2,1,1]
["S1741","Rifabutin (LM427)","f5","L8000-04","in 10mM DMSO","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Bacterial","Microbiology","Rifabutin (LM427, Ansamycin) is a semisynthetic ansamycin antibiotic, used in the treatment of Mycobacterium avium intracellulare (MAI) and tuberculosis.",{"v":847,"d":"847.00"},"72559-06-9",{"v":60,"d":"60.00"},70.84,"<1","N/A","http://selleckchem.com/products/Rifabutin(Mycobutin).html","C46H62N4O11","free base","LM427, Ansamycin","COC1\\C=C\\OC2(C)OC3=C(C2=O)C4=C(C(=C3C)O)C(=O)C(=C5NC6(CCN(CC6)CC(C)C)N=C45)NC(=O)/C(=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)C",3.931,9,5,5]
["S1742","Nevirapine (NSC 641530)","g5","L8000-04","in 10mM DMSO","Reverse Transcriptase","Microbiology","Nevirapine (NSC 641530,NVP) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.",{"v":266.3,"d":"266.30"},"129618-40-2",{"v":53,"d":"53.00"},199.02,"<1","N/A","http://selleckchem.com/products/Nevirapine(Viramune).html","C15H14N4O","free base","NSC 641530,NVP","CC1=CC=NC2=C1NC(=O)C3=C(N=CC=C3)N2C4CC4",2.293,3,1,1]
["S1747","Nimodipine","h5","L8000-04","in 10mM DMSO","Autophagy,Calcium Channel","Transmembrane Transporters","Nimodipine (BAY E 9736) is a dihydropyridine calcium channel blocker and an autophagy inhibitor, used in the treatment of high blood pressure.",418.44,"66085-59-4",{"v":84,"d":"84.00"},200.75,"<1","N/A","http://selleckchem.com/products/Nimodipine(Nimotop).html","C21H26N2O7","free base","BAY E 9736","COCCOC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OC(C)C)C",2.361,5,1,10]
["S1754","Oxybutynin","a6","L8000-04","in 10mM DMSO","AChR","Neuronal Signaling","Oxybutynin is a competitive antagonist of the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor, used to relieve urinary and bladder difficulties.",357.49,"5633-20-5",{"v":71,"d":"71.00"},198.61,"<1","N/A","http://selleckchem.com/products/Oxybutynin(Ditropan).html","C22H31NO3","Free Base","N/A","CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)C2=CC=CC=C2",4.646,2,0,10]
["S1756","Enoxacin","b6","L8000-04","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Enoxacin (AT-2266, CI919, Pd107779, NSC 629661) is an oral broad-spectrum fluoroquinolone antibacterial agent by inhibiting bacterial DNA gyrase and topoisomerase IV, used to treat a wide variety of infections.",320.32,"74011-58-8",{"v":32,"d":"32.00"},{"v":99.9,"d":"99.90"},"<1","N/A","http://selleckchem.com/products/Enoxacin(Penetrex).html","C15H17FN4O3","free base","AT-2266, CI919, Pd107779, NSC 629661","CCN1C=C(C(O)=O)C(=O)C2=CC(=C(N=C12)N3CCNCC3)F",-1.483,3,1,3]
["S1759","Pitavastatin (NK-104) calcium","c6","L8000-04","in 10mM DMSO","Apoptosis related,Autophagy,COVID-19,HMG-CoA Reductase,Mitophagy","Metabolism","Pitavastatin Calcium (NK-104, P-872441, itavastatin, nisvastatin), a novel member of the medication class of statins, is a calcium salt formulation of pitavastatin which is a highly effective HMG-CoA reductase inhibitor. Pitavastatin Calcium attenuates AGEs-induced mitophagy via inhibition of ROS generation. Pitavastatin Calcium induces autophagy and apoptosis.",880.98,"147526-32-7",{"v":51,"d":"51.00"},57.89,"<1","N/A","http://selleckchem.com/products/Pitavastatin-calcium(Livalo).html","C50H46CaF2N2O8","Calcium salt","NK-104, P-872441, itavastatin, nisvastatin","[Ca++].OC(CC(O)C=CC1=C(C2=CC=C(F)C=C2)C3=CC=CC=C3N=C1C4CC4)CC([O-])=O.OC(CC(O)C=CC5=C(C6=CC=C(F)C=C6)C7=CC=CC=C7N=C5C8CC8)CC([O-])=O",{"v":4.96,"d":"4.960"},2,4,16]
["S1760","Rifapentine","d6","L8000-04","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Rifapentine (MDL473) is an antibiotic, which inhibits DNA-dependent RNA polymerase activity, used to treat tuberculosis.",877.03,"61379-65-5",{"v":100,"d":"100.00"},114.02,"<1","N/A","http://selleckchem.com/products/Rifapentine(Priftin).html","C47H64N4O12","free base","MDL473","COC1\\C=C\\OC2(C)OC3=C(C2=O)C4=C(O)C(=C(NC(=O)\\C(=C\\C=C\\C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)C)C(=C4C(=C3C)O)O)\\C=N\\N5CCN(CC5)C6CCCC6",4.664,8,6,6]
["S1761","Suprofen","e6","L8000-04","in 10mM DMSO","COX","Neuronal Signaling","Suprofen(TN-762) is a dual COX-1/COX-2 inhibitor, used as a non-steroidal anti-inflammatory analgesic and antipyretic.",260.31,"40828-46-4",{"v":52,"d":"52.00"},199.76,"<1","N/A","http://selleckchem.com/products/Suprofen(Profenal).html","C14H12O3S","free base","TN-762","CC(C(O)=O)C1=CC=C(C=C1)C(=O)C2=CC=CS2",3.314,2,0,4]
["S1763","Quetiapine (ICI-204636) fumarate","f6","L8000-04","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Quetiapine Fumarate (ICI-204636) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression and shows affinity for various neurotransmitter receptors including serotonin, dopamine, histamine, and adrenergic receptors.",883.09,"111974-72-2",{"v":36,"d":"36.00"},40.77,"<1","N/A","http://selleckchem.com/products/Quetiapine-fumarate(Seroquel).html","C46H54N6O8S2","Fumarate","ICI-204636 fumarate","OCCOCCN1CCN(CC1)C2=NC3=CC=CC=C3SC4=C2C=CC=C4.OCCOCCN5CCN(CC5)C6=NC7=CC=CC=C7SC8=C6C=CC=C8.OC(=O)\\C=C\\C(O)=O",-0.718,6,2,14]
["S1764","Rifampin (NSC-113926)","g6","L8000-04","in 10mM DMSO","Antibiotics for Plant Cell Culture,Antineoplastic and Immunosuppressive Antibiotics,DNA/RNA Synthesis,Selection Antibiotics for Transfected Cell","DNA Damage/DNA Repair","Rifampin (NSC-113926, Rimactane, Rifampicin) is a DNA-dependent RNA polymerase inhibitor, used to treat a number of bacterial infections.",822.94,"13292-46-1",{"v":100,"d":"100.00"},121.52,"<1","N/A","http://selleckchem.com/products/Rifampin(Rifadin).html","C43H58N4O12","free base","Rimactane, Rifampicin,NSC-113926","COC1\\C=C\\OC2(C)OC3=C(C2=O)C4=C(O)C(=C(NC(=O)\\C(=C\\C=C\\C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)C)C(=C4C(=C3C)O)O)\\C=N\\N5CCN(C)CC5",3.262,8,6,5]
["S1768","Cefditoren Pivoxil","h6","L8000-04","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Cefditoren Pivoxil (ME-1207) is a broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria.",620.72,"117467-28-4",{"v":100,"d":"100.00"},{"v":161.1,"d":"161.10"},"<1","N/A","http://selleckchem.com/products/Cefditoren-pivoxil.html","C25H28N6O7S3","free base","ME-1207","CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C)\\C=C/C3=C(C)N=CS3)C4=CSC(=N4)N",1.926,10,2,12]
["S1770","Sulfadiazine","a7","L8000-04","in 10mM DMSO","Antibiotics","Microbiology","Sulfadiazine is a sulfonamide antibiotic.",250.28,"68-35-9",{"v":50,"d":"50.00"},199.78,"<1","N/A","http://selleckchem.com/products/Sulfadiazine.html","C10H10N4O2S","free base","N/A","NC1=CC=C(C=C1)[S](=O)(=O)NC2=NC=CC=N2",0.313,4,2,3]
["S1771","Chlorprothixene","b7","L8000-04","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Chlorprothixene(Minithixen,Truxal) has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively.",315.86,"113-59-7",{"v":6,"d":"6.00"},{"v":19,"d":"19.00"},"<1","N/A","http://selleckchem.com/products/Chlorprothixene.html","C18H18ClNS","free base","Minithixen,Truxal","CN(C)CC/C=C1/C2=CC=CC=C2SC3=C1C=C(Cl)C=C3",5.123,0,0,3]
["S1774","Thioguanine (NSC 752)","c7","L8000-04","in 10mM DMSO","DNA Methyltransferase","Epigenetics","Thioguanine (NSC 752, 6-Thioguanine, 2-Amino-6-purinethiol), a purine antimetabolite, inhibits DNMT1 activity through ubiquitin-targeted degradation, used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis) and organ transplant recipients.",167.19,"154-42-7",{"v":9,"d":"9.00"},53.83,"<1","N/A","http://selleckchem.com/products/Thioguanine.html","C5H5N5S","free base","NSC 752,6-Thioguanine, 2-Amino-6-purinethiol","NC1=NC(=S)C2=C(N1)N=C[NH]2",0.236,2,3,0]
["S1775","Thiotepa","d7","L8000-04","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics","Others","Thiotepa (Thioplex, Tiofosyl, Tiofosfamid, Triethylenethiophosphoramide) is an alkylating agent used to treat cancer.",189.22,"52-24-4",{"v":100,"d":"100.00"},528.49,{"v":100,"d":"100.00"},528.49,"http://selleckchem.com/products/thiotepa-thioplex.html","C6H12N3PS","free base","Tiofosyl, Tiofosfamid, Triethylenethiophosphoramide","S=[P](N1CC1)(N2CC2)N3CC3",-0.762,0,0,3]
["S1776","Toremifene Citrate (NK 622)","e7","L8000-04","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Toremifene Citrate (NK 622, NSC 613680) is an oral selective estrogen receptor modulator (SERM), used in the treatment of advanced breast cancer.",598.08,"89778-27-8",{"v":100,"d":"100.00"},{"v":167.2,"d":"167.20"},"<1","N/A","http://selleckchem.com/products/Toremifene-Citrate(Fareston).html","C32H36ClNO8","Citrate","NSC 613680,NK 622 Citrate","CN(C)CCOC1=CC=C(C=C1)\\C(=C(CCCl)/C2=CC=CC=C2)C3=CC=CC=C3.OC(=O)CC(O)(CC(O)=O)C(O)=O",1.945,4,0,14]
["S1777","Ethionamide","f7","L8000-04","in 10mM DMSO","Antibiotics","Microbiology","Ethionamide (Bayer 5312) is an antibiotic used in the treatment of tuberculosis.",166.24,"536-33-4",{"v":33,"d":"33.00"},198.51,"<1","N/A","http://selleckchem.com/products/Ethionamide.html","C8H10N2S","free base","Bayer 5312","CCC1=NC=CC(=C1)C(N)=S",1.498,1,1,2]
["S1778","Trifluridine (NSC 75520)","g7","L8000-04","in 10mM DMSO","DNA/RNA Synthesis,Thymidylate Synthase","DNA Damage/DNA Repair","Trifluridine (NSC 529182, NSC 75520, Viroptic, Trifluorothymidine, TFT) is an anti-herpesvirus antiviral agent by interacting viral DNA replication, used primarily on the eye.",{"v":296.2,"d":"296.20"},"70-00-8",{"v":59,"d":"59.00"},199.19,{"v":59,"d":"59.00"},199.19,"http://selleckchem.com/products/Trifluridine(Viroptic).html","C10H11F3N2O5","free base","NSC 529182, NSC 75520, Viroptic, Trifluorothymidine, TFT","OCC1OC(CC1O)N2C=C(C(=O)NC2=O)C(F)(F)F",-0.782,3,3,3]
["S1782","Azacitidine (5-Azacytidine)","h7","L8000-04","in 10mM DMSO","Autophagy,DNA Methyltransferase,Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Azacitidine (5-Azacytidine, 5-AzaC, Ladakamycin, AZA, 5-Aza, CC-486,NSC 102816) is a nucleoside analogue of cytidine that specifically inhibits DNA methylation by trapping DNA methyltransferases. Azacitidine induces mitochondrial apoptosis and autophagy.",{"v":244.2,"d":"244.20"},"320-67-2",{"v":48,"d":"48.00"},196.56,"<1","N/A","http://selleckchem.com/products/Azacitidine(Vidaza).html","C8H12N4O5","free base","5-AzaC,Ladakamycin, AZA,5-Aza, CC-486,NSC 102816,5-Azacytidine","NC1=NC(=O)N(C=N1)C2OC(CO)C(O)C2O",-2.505,4,4,2]
["S1784","Vidarabine","a8","L8000-04","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Vidarabine is an antiviral drug by interfering with the synthesis of viral DNA, used to treat herpes simplex and varicella zoster viruses.",267.24,"5536-17-4",{"v":53,"d":"53.00"},198.32,{"v":3,"d":"3.00"},11.23,"http://selleckchem.com/products/Vidarabine(Vira-A).html","C10H13N5O4","free base","N/A","NC1=C2N=C[N](C3OC(CO)C(O)C3O)C2=NC=N1",-1.881,4,4,2]
["S1786","Verteporfin (CL 318952)","b8","L8000-04","in 10mM DMSO","Apoptosis related,Autophagy,TEAD,VDA,YAP","Angiogenesis","Verteporfin (CL 318952, Visudyne) is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth.  It is also a potent second-generation photosensitizing agent derived from porphyrin. Verteporfin is an autophagy inhibitor. Verteporfin inhibits cell proliferation and induces apoptosis.",718.79,"129497-78-5",{"v":100,"d":"100.00"},139.12,"<1","N/A","http://selleckchem.com/products/Verteporfin(Visudyne).html","C41H42N4O8","free base","CL 318952, Visudyne","COC(=O)CCC1=C(C)C2=CC3=NC(=CC4=C(C)C(=C([NH]4)C=C5N=C(C=C1[NH]2)C(=C5C)CCC(O)=O)C=C)C6=CC=C(C(C(=O)OC)C36C)C(=O)OC",7.789,9,2,12]
["S1787","Teniposide","c8","L8000-04","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Teniposide (NSC 122819, VM-26) is a chemotherapeutic medication mainly used in the treatment of childhood acute lymphocytic leukemia (ALL).",656.65,"29767-20-2",{"v":40,"d":"40.00"},60.92,"<1","N/A","http://selleckchem.com/products/Teniposide(Vumon).html","C32H32O13S","free base","NSC 122819, VM-26","COC1=CC(=CC(=C1O)OC)C2C3C(COC3=O)C(OC4OC5COC(OC5C(O)C4O)C6=CC=CS6)C7=CC8=C(OCO8)C=C27",2.516,10,3,6]
["S1790","Rifaximin","d8","L8000-04","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Rifaximin is a RNA synthesis inhibitor by binding the β subunit of the bacterial DNA-dependent RNA polymerase, used to treat traveler's diarrhea caused by certain bacteria.",785.88,"80621-81-4",{"v":47,"d":"47.00"},59.81,"<1","N/A","http://selleckchem.com/products/Rifaximin(Xifaxan).html","C43H51N3O11","free base","N/A","COC1\\C=C\\OC2(C)OC3=C(C2=O)C4=C(C(=C3C)O)C(=C(NC(=O)\\C(=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)C)C5=C4N=C6C=C(C)C=C[N]56)O",4.805,8,5,3]
["S1792","Simvastatin (MK 733)","e8","L8000-04","in 10mM DMSO","Apoptosis related,Autophagy,Ferroptosis,HMG-CoA Reductase,Mitophagy","Metabolism","Simvastatin (MK-0733, MK 733) is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM in cell-free assays. Simvastatin induces ferroptosis, mitophagy, autophagy and apoptosis.",418.57,"79902-63-9",{"v":83,"d":"83.00"},198.29,"<1","N/A","http://selleckchem.com/products/Simvastatin(Zocor).html","C25H38O5","free base","MK-0733, MK 733","CCC(C)(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C12",4.634,4,1,7]
["S1793","Ramipril","f8","L8000-04","in 10mM DMSO","ACE,RAAS","Endocrinology & Hormones","Ramipril(HOE-498) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.",416.51,"87333-19-5",{"v":83,"d":"83.00"},199.27,"<1","N/A","http://selleckchem.com/products/Ramipril(Altace).html","C23H32N2O5","free base","HOE-498","CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCC3CC2C(O)=O",0.308,4,1,10]
["S1794","Fenofibrate (NSC-281319)","g8","L8000-04","in 10mM DMSO","Autophagy,P450 (e.g. CYP17),PPAR","Metabolism","Fenofibrate (NSC-281319) is a compound of the fibrate class and fibric acid derivative. Fenofibrate is a selective agonist of PPARα with EC50 of 30 μM. Fenofibrate binds to and inhibits cytochrome P450 epoxygenase (CYP)2C with IC50 of 0.2 μM, 0.7 μM and 9.7 μM for CYP2C19, CYP2B6 and CYP2C9, respectively. Fenofibrate induces autophagy.",360.83,"49562-28-9",{"v":72,"d":"72.00"},199.54,"<1","N/A","http://selleckchem.com/products/Fenofibrate(Tricor).html","C20H21ClO4","free base","NSC-281319","CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(Cl)C=C2",5.111,4,0,7]
["S1799","Ranolazine","h8","L8000-04","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Ranolazine (CVT 303, RS 43285-003) is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina.",427.54,"95635-55-5",{"v":86,"d":"86.00"},201.15,"<1","N/A","http://selleckchem.com/products/Ranolazine(Ranexa).html","C24H33N3O4","Free Base","CVT 303, RS 43285-003","COC1=CC=CC=C1OCC(O)CN2CCN(CC2)CC(=O)NC3=C(C)C=CC=C3C",2.991,3,2,9]
["S1801","Ranitidine Hydrochloride","a9","L8000-04","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Ranitidine (AH19065) is a histamine H2-receptor antagonist, used to treat stomach or intestinal ulcers.",350.86,"66357-59-3",{"v":70,"d":"70.00"},199.51,{"v":70,"d":"70.00"},199.51,"http://selleckchem.com/products/Ranitidine-hydrochloride(Zantac).html","C13H22N4O3S.HCl","Hydrochloride","AH19065","Cl.CNC(/NCCSCC1=CC=C(CN(C)C)O1)=C\\[N+]([O-])=O",1.421,1,2,10]
["S1805","Acetylcholine Chloride","b9","L8000-04","in 10mM DMSO","AChR","Neuronal Signaling","The chemical compound Acetylcholine Chloride(ACh chloride) is a neurotransmitter in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans.",181.66,"60-31-1",{"v":36,"d":"36.00"},198.17,{"v":36,"d":"36.00"},198.17,"http://www.selleck.cn/products/Acetylcholine-chloride.html","C7H16NO2.Cl","Chloride","ACh chloride","[Cl-].CC(=O)OCC[N+](C)(C)C",-3.869,2,0,4]
["S1806","Acipimox","c9","L8000-04","in 10mM DMSO","Others","Others","Acipimox (Olbemox,K-9321) is a niacin derivative used as a hypolipidemic agent.",154.12,"51037-30-0",{"v":31,"d":"31.00"},201.14,"<1","N/A","http://selleckchem.com/products/Acipimox.html","C6H6N2O3","free base","Olbemox,K-9321","CC1=CN=C(C=[N+]1[O-])C(O)=O",-0.975,2,0,1]
["S1808","Nifedipine (BAY-a-1040)","d9","L8000-04","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Nifedipine (BAY-a-1040) is a dihydropyridine calcium channel blocker, used to lower hypertension and to treat angina.",346.33,"21829-25-4",{"v":69,"d":"69.00"},199.23,"<1","N/A","http://selleckchem.com/products/Nifedipine(Adalat).html","C17H18N2O6","free base","BAY-a-1040","COC(=O)C1=C(C)NC(=C(C1C2=C(C=CC=C2)[N+]([O-])=O)C(=O)OC)C",1.766,4,1,6]
["S1811","Amiloride (MK-870) HCl","e9","L8000-04","in 10mM DMSO","Calcium Channel,Serine Protease,Sodium Channel","Transmembrane Transporters","Amiloride (MK-870 HCl) is a selective T-type calcium channel blocker, an epithelial sodium channel blocker and a selective inhibitor of urokinase plasminogen activator (uPA)(Ki=7 μM).",266.09,"2016-88-8",{"v":53,"d":"53.00"},199.18,{"v":6,"d":"6.00"},22.55,"http://selleckchem.com/products/Amiloride-hydrochloride(Midamor).html","C6H8ClN7O.HCl","Hydrochloride","MK-870 HCl","Cl.NC(=N)NC(=O)C1=NC(=C(N)N=C1N)Cl",-0.366,3,4,2]
["S1816","Chlorpheniramine Maleate","f9","L8000-04","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Chlorpheniramine Maleate (Chlorpheniramine maleate, Chlorphenamine, NCI-C55265) is an histamine H1 receptor antagonist with IC50 of 12 nM.",390.86,"113-92-8",{"v":78,"d":"78.00"},199.56,{"v":78,"d":"78.00"},199.56,"http://selleckchem.com/products/Chlorpheniramine-maleate.html","C16H19ClN2.C4H4O4","Maleate","NCI-C55265","CN(C)CCC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.OC(=O)\\C=C/C(O)=O",{"v":0.7,"d":"0.700"},3,0,7]
["S1820","Clofibrate","g9","L8000-04","in 10mM DMSO","Others","Others","Clofibrate (Atromid-S), a fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia.",{"v":242.7,"d":"242.70"},"637-07-0",{"v":7,"d":"7.00"},28.84,"<1","N/A","http://www.selleck.cn/products/Clofibrate(Atromid-S).html","C12H15ClO3","Free Base","N/A","CCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1",3.329,3,0,5]
["S1827","Betaxolol HCl","h9","L8000-04","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Betaxolol (SL 75212) is a β1 adrenergic receptor blocker with IC50 of 6 μM.",343.89,"63659-19-8",{"v":69,"d":"69.00"},200.65,{"v":69,"d":"69.00"},200.65,"http://selleckchem.com/products/betaxolol-hydrochloride-betoptic.html","C18H29NO3.HCl","Hydrochloride","SL 75212 HCl","Cl.CC(C)NCC(O)COC1=CC=C(CCOCC2CC2)C=C1",2.959,2,2,11]
["S1828","Proparacaine HCl","a10","L8000-04","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Proparacaine HCl(Proxymetacaine Hydrochloride) is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM.",330.85,"5875-06-9",{"v":12,"d":"12.00"},36.27,{"v":66,"d":"66.00"},199.49,"http://selleckchem.com/products/proparacaine-hcl.html","C16H26N2O3.HCl","Hydrochloride","Proxymetacaine Hydrochloride","Cl.CCCOC1=C(N)C=C(C=C1)C(=O)OCCN(CC)CC",3.013,3,1,10]
["S1829","Pranlukast","b10","L8000-04","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Pranlukast (ONO-1078,ono-rs-411) is an orally administered, and selective antagonist of the cysteinyl leukotrienes (LT) C(4), LTD(4) and LTE(4), used in the prophylactic treatment of chronic bronchial asthma.",{"v":481.5,"d":"481.50"},"103177-37-3",{"v":11,"d":"11.00"},22.85,"<1","N/A","http://selleckchem.com/products/pranlukast.html","C27H23N5O4","free base","ONO-1078,ono-rs-411","O=C(NC1=CC2=C(C=C1)C(=O)C=C(O2)C3=NN=N[NH]3)C4=CC=C(OCCCCC5=CC=CC=C5)C=C4",4.232,7,2,9]
["S1830","Oxfendazole","c10","L8000-04","in 10mM DMSO","Parasite","Microbiology","Oxfendazole (RS-8858,Fenbendazole sulfoxide) is a broad spectrum benzimidazole anthelmintic.",315.35,"53716-50-0",{"v":10,"d":"10.00"},31.71,"<1","N/A","http://selleckchem.com/products/oxfendazole.html","C15H13N3O3S","free base","RS-8858,Fenbendazole sulfoxide","COC(=O)NC1=NC2=C([NH]1)C=C(C=C2)[S](=O)C3=CC=CC=C3",2.657,4,2,4]
["S1831","Carvedilol","d10","L8000-04","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Carvedilol (BM-14190, SKF 105517) is a non-selective beta blocker/alpha-1 blocker, used to treat congestive heart failure (CHF) and high blood pressure.",406.47,"72956-09-3",{"v":81,"d":"81.00"},199.28,"<1","N/A","http://selleckchem.com/products/carvedilol.html","C24H26N2O4","free base","BM-14190, SKF 105517","COC1=CC=CC=C1OCCNCC(O)COC2=C3C(=CC=C2)[NH]C4=C3C=CC=C4",4.014,3,3,10]
["S1833","Butoconazole nitrate","e10","L8000-04","in 10mM DMSO","Fungal,IFN,Interleukins,TNF-alpha","Microbiology","Butoconazole nitrate (RS-35887) is an anti-fungal agent that inhibits PHA-stimulated release of cytokines-- IL-2, TNFα, IFN and GM-CSF from human peripheral blood lymphocytes (IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively).",474.79,"64872-77-1",{"v":95,"d":"95.00"},200.09,"<1","N/A","http://selleckchem.com/products/butoconazole-nitrate.html","C19H17Cl3N2S.HNO3","Nitrate","RS-35887","O[N+]([O-])=O.ClC1=CC=C(CCC(C[N]2C=CN=C2)SC3=C(Cl)C=CC=C3Cl)C=C1",5.238,1,0,7]
["S1835","Azithromycin (CP-62993)","f10","L8000-04","in 10mM DMSO","Antibiotics,Antibiotics for Mammalian Cell Culture,Autophagy,Bacterial,COVID-19","Autophagy","Azithromycin (CP-62993, XZ-450) is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.",748.98,"83905-01-5",{"v":100,"d":"100.00"},133.51,"<1","N/A","http://selleckchem.com/products/azithromycin-zithromax.html","C38H72N2O12","Free Base","XZ-450,CP-62993","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)CN(C)C(C)C(O)C1(C)O",2.078,7,3,7]
["S1839","Chloroxine","g10","L8000-04","in 10mM DMSO","Bacterial","Microbiology","Chloroxine is a synthetic antibacterial compound that is effective in the treatment of dandruff and seborrheic dermatitis when incorporated in a shampoo.",214.05,"773-76-2",{"v":43,"d":"43.00"},200.89,"<1","N/A","http://selleckchem.com/products/Chloroxine.html","C9H5Cl2NO","free base","N/A","OC1=C(Cl)C=C(Cl)C2=C1N=CC=C2",3.103,1,1,0]
["S1840","Lomustine","h10","L8000-04","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Lomustine (NSC79037, Gleostine, CeeNU, CCNU) inhibits cancer cells by damaging the DNA and stops cells from dividing.",{"v":233.7,"d":"233.70"},"13010-47-4",{"v":46,"d":"46.00"},196.83,"<1","N/A","http://selleckchem.com/products/Lomustine(CeeNU).html","C9H16ClN3O2","free base","NSC79037, Gleostine, CeeNU, CCNU","ClCCN(N=O)C(=O)NC1CCCCC1",2.394,2,1,4]
["S1845","Cimetidine","a11","L8000-04","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Cimetidine (SKF-92334), a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.",252.34,"51481-61-9",{"v":51,"d":"51.00"},202.11,"<1","N/A","http://selleckchem.com/products/Cimetidine(Tagamet).html","C10H16N6S","free base","SKF-92334","CNC(NCCSCC1=C(C)[NH]C=N1)=NC#N",0.007,2,3,7]
["S1847","Clemastine (HS-592) fumarate","b11","L8000-04","in 10mM DMSO","Autophagy,Histamine Receptor,mTOR","Neuronal Signaling","Clemastine Fumarate (HS-592, Meclastine) is a selective histamine H1 receptor antagonist with IC50 of 3 nM. Clemastine stimulates autophagy via mTOR pathway.",459.96,"14976-57-9",{"v":35,"d":"35.00"},76.09,"<1","N/A","http://selleckchem.com/products/Clemastine-Fumarate.html","C21H26ClNO.C4H4O4","Fumarate","HS-592 fumarate, Meclastine fumarate","CN1CCCC1CCOC(C)(C2=CC=CC=C2)C3=CC=C(Cl)C=C3.OC(=O)\\C=C\\C(O)=O",{"v":1.81,"d":"1.810"},3,0,8]
["S1848","Curcumin","c11","L8000-04","in 10mM DMSO","Apoptosis related,Autophagy,Epigenetic Reader Domain,Ferroptosis,HCV,HDAC,Histone Acetyltransferase,HIV,Influenza Virus,NF-κB,Nrf2","Epigenetics","Curcumin (Diferuloylmethane, Natural Yellow 3, Turmeric yellow) is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase（IC50~25 μM）and Histone deacetylase (HDAC); activates Nrf2 pathway and supresses the activation of NF-κB. Curcumin induces mitophagy, autophagy, apoptosis, and cell cycle arrest with antitumor activity. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus, hepatitis C virus, HIV and so on.",368.38,"458-37-7",{"v":73,"d":"73.00"},198.16,"<1","N/A","http://selleckchem.com/products/Curcumin.html","C21H20O6","free base","Diferuloylmethane, Natural Yellow 3, Turmeric yellow","COC1=CC(=CC=C1O)/C=C/C(O)=C/C(=O)/C=C/C2=CC(=C(O)C=C2)OC",3.573,3,3,7]
["S1849","Daidzein","d11","L8000-04","in 10mM DMSO","PPAR","Metabolism","Daidzein is a natural isoflavone phytoestrogen found in Leguminosae, used as a component of foods and dietary supplements. Daidzein is a soy isoflavone, which acts as a PPAR activator.",254.24,"486-66-8",{"v":51,"d":"51.00"},{"v":200.6,"d":"200.60"},"<1","N/A","http://selleckchem.com/products/Daidzein.html","C15H10O4","free base","N/A","OC1=CC=C(C=C1)C2=COC3=CC(=CC=C3C2=O)O",2.382,2,2,1]
["S1854","Bifonazole","e11","L8000-04","in 10mM DMSO","Fungal","Microbiology","Bifonazole (Bay h 4502,(±)-bifonazole) is a substituted imidazole antifungal agent.",310.39,"60628-96-8",{"v":62,"d":"62.00"},199.75,"<1","N/A","http://selleckchem.com/products/bifonazole.html","C22H18N2","free base","Bay h 4502,(±)-bifonazole","C1=CC=C(C=C1)C([N]2C=CN=C2)C3=CC=C(C=C3)C4=CC=CC=C4",4.637,1,0,4]
["S1855","Pefloxacin Mesylate","f11","L8000-04","in 10mM DMSO","Bacterial","Microbiology","Pefloxacin Mesylate(Pefloxacinium mesylate) is a synthetic chemotherapeutic agent and an antibacterial agent with IC50 of 6.7 nM.",429.46,"70458-95-6",{"v":14,"d":"14.00"},{"v":32.6,"d":"32.60"},{"v":67,"d":"67.00"},156.01,"http://selleckchem.com/products/pefloxacin-mesylate.html","C17H20FN3O3.CH4O3S","Mesylate","Pefloxacinium mesylate","CCN1C=C(C(O)=O)C(=O)C2=CC(=C(C=C12)N3CCN(C)CC3)F.C[S](O)(=O)=O",-1.618,2,0,3]
["S1856","Metoprolol Tartrate","g11","L8000-04","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Metoprolol Tartrate (CGP 2175E) is a selective β1 receptor blocker medication, used to treat hypertension and heart failure.",684.81,"56392-17-7",{"v":100,"d":"100.00"},146.03,{"v":100,"d":"100.00"},146.03,"http://selleckchem.com/products/metoprolol-tartrate.html","2C15H25NO3.C4H6O6","Tartrate","CGP 2175E","COCCC1=CC=C(OCC(O)CNC(C)C)C=C1.COCCC2=CC=C(OCC(O)CNC(C)C)C=C2.OC(C(O)C(O)=O)C(O)=O",-3.559,6,6,21]
["S1858","Dienestrol","h11","L8000-04","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Dienestrol(Restrol) is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist.",266.33,"84-17-3",{"v":53,"d":"53.00"},{"v":199,"d":"199.00"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/Dienestrol(Restrol).html","C18H18O2","Free Base","Restrol","C/C=C(C1=CC=C(O)C=C1)/C(=C/C)C2=CC=C(O)C=C2",4.692,0,2,3]
["S1859","Diethylstilbestrol","a2","L8000-05","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Diethylstilbestrol (Stilbestrol) is a synthetic nonsteroidal estrogen, used to prevent miscarriage and other pregnancy complications.",268.35,"56-53-1",{"v":54,"d":"54.00"},201.23,"<1","N/A","http://selleckchem.com/products/Diethylstilbestrol(Stilbestrol).html","C18H20O2","free base","Stilbestrol","CCC(/C1=CC=C(O)C=C1)=C(CC)\\C2=CC=C(O)C=C2",5.137,0,2,4]
["S1869","Dapoxetine HCl","b2","L8000-05","in 10mM DMSO","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Dapoxetine HCl (LY-210448) is a short-acting novel selective serotonin reuptake inhibitor, used for the treatment of premature ejaculation.",341.87,"129938-20-1",{"v":68,"d":"68.00"},198.91,{"v":68,"d":"68.00"},198.91,"http://selleckchem.com/products/Dapoxetine-hydrochloride(Priligy).html","C21H23NO.HCl","Hydrochloride","LY-210448","Cl.CN(C)C(CCOC1=C2C=CC=CC2=CC=C1)C3=CC=CC=C3",4.917,1,0,6]
["S1878","Ganciclovir (BW 759)","c2","L8000-05","in 10mM DMSO","CMV","Microbiology","Ganciclovir (RS-21592, BW-759, 2'-Nor-2'-deoxyguanosine) is an antiviral drug for feline herpesvirus type-1 with IC50 of 5.2 μM in a cell-free assay.",255.23,"82410-32-0",{"v":27,"d":"27.00"},105.79,"<1","N/A","http://selleckchem.com/products/ganciclovir.html","C9H13N5O4","free base","RS-21592, BW-759, 2'-Nor-2'-deoxyguanosine","NC1=NC2=C(N=C[N]2COC(CO)CO)C(=O)N1",-1.934,4,4,5]
["S1880","Roxatidine Acetate HCl","d2","L8000-05","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Roxatidine Acetate HCl(HOE 760) is a specific and competitive histamin H2-receptor antagonist, with IC50 of 3.2 μM, inhibits gastric acid secretion and ulcer formation.",{"v":384.9,"d":"384.90"},"93793-83-0",{"v":77,"d":"77.00"},200.05,{"v":77,"d":"77.00"},200.05,"http://selleckchem.com/products/roxatidine-acetate-hcl.html","C19H28N2O4.HCl","Hydrochloride","HOE 760","Cl.CC(=O)OCC(=O)NCCCOC1=CC=CC(=C1)CN2CCCCC2",2.148,4,1,10]
["S1883","Idoxuridine","e2","L8000-05","in 10mM DMSO","Antiviral","Microbiology","Idoxuridine (NSC 39661, SKF 14287,5-Iodo-2′-deoxyuridine,5-IUdR,IdUrd) is an antiviral agent for feline herpesvirus type-1 with IC50 of 4.3 μM.",{"v":354.1,"d":"354.10"},"54-42-2",{"v":35,"d":"35.00"},98.84,"<1","N/A","http://selleckchem.com/products/idoxuridine.html","C9H11IN2O5","free base","NSC 39661, SKF 14287,5-Iodo-2′-deoxyuridine,5-IUdR,IdUrd","OCC1OC(CC1O)N2C=C(I)C(=O)NC2=O",-1.402,3,3,2]
["S1884","Sparfloxacin","f2","L8000-05","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Sparfloxacin (AT-4140, CI-978, PD 131501,Zagam) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity.",{"v":392.4,"d":"392.40"},"110871-86-8",{"v":9,"d":"9.00"},22.94,"<1","N/A","http://selleckchem.com/products/sparfloxacin.html","C19H22F2N4O3","free base","AT-4140, CI-978, PD 131501,Zagam","CC1CN(CC(C)N1)C2=C(F)C3=C(C(=C2F)N)C(=O)C(=CN3C4CC4)C(O)=O",-1.056,2,2,3]
["S1888","Deflazacort","g2","L8000-05","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Deflazacort (MDL 458) is a glucocorticoid used as an anti-inflammatory and immunosuppressant.",441.52,"14484-47-0",{"v":88,"d":"88.00"},199.31,"<1","N/A","http://selleckchem.com/products/Deflazacor.html","C25H31NO6","free base","MDL 458","CC(=O)OCC(=O)C12N=C(C)OC1CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC23C",{"v":1.67,"d":"1.670"},6,1,4]
["S1890","Nizatidine","h2","L8000-05","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Nizatidine is a histamine H2 receptor antagonist with IC50 of 0.9 nM, also inhibits AChE with IC50 of 6.7 μM.",331.46,"76963-41-2",{"v":66,"d":"66.00"},199.12,{"v":28,"d":"28.00"},84.47,"http://selleckchem.com/products/Nizatidine(Axid).html","C12H21N5O2S2","free base","N/A","CNC(/NCCSCC1=CSC(=N1)CN(C)C)=C/[N+]([O-])=O",0.643,1,2,10]
["S1894","Valsartan (CGP-48933)","a3","L8000-05","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Valsartan (CGP-48933) is a selective angiotensin II receptor antagonist, used to treat high blood pressure and congestive heart failure.",435.52,"137862-53-4",{"v":87,"d":"87.00"},199.76,"<1","N/A","http://selleckchem.com/products/Valsartan(Diovan).html","C24H29N5O3","free base","CGP-48933","CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=N[NH]N=N3)C(C(C)C)C(O)=O",4.538,5,1,10]
["S1895","Dipyridamole (NSC 515776)","b3","L8000-05","in 10mM DMSO","PDE","Metabolism","Dipyridamole (NSC-515776, Persantine) is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells.",504.63,"58-32-2",{"v":101,"d":"101.00"},200.15,"<1","N/A","http://selleckchem.com/products/Dipyridamole(Permole,-Persantine).html","C24H40N8O4","free base","Persantine,NSC-515776","OCCN(CCO)C1=NC2=C(N=C(N=C2N3CCCCC3)N(CCO)CCO)C(=N1)N4CCCCC4",2.483,4,4,12]
["S1896","Hydroxyurea (NSC-32065)","c3","L8000-05","in 10mM DMSO","Apoptosis related,Autophagy,DNA/RNA Synthesis,HIV","DNA Damage/DNA Repair","Hydroxyurea (NSC-32065, NCI-C04831, Hydroxycarbamide) is an antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase. Hydroxyurea activates apoptosis and autophagy. Hydroxyurea is used to treat HIV infection.",76.05,"127-07-1",{"v":15,"d":"15.00"},197.24,{"v":15,"d":"15.00"},197.24,"http://selleckchem.com/products/Hydroxyurea(Cytodrox).html","CH4N2O2","free base","NCI-C04831, Hydroxycarbamide,NSC-32065","NC(=O)NO",{"v":-1.03,"d":"-1.030"},1,2,0]
["S1899","Nicotinamide (NSC 13128)","d3","L8000-05","in 10mM DMSO","Sirtuin","DNA Damage/DNA Repair","Nicotinamide (Niacinamide, Vitamin PP, Nicotinic acid amide, Vitamin B3, NSC 27452,NSC 13128), a water-soluble vitamin, is an active component of coenzymes NAD and NADP, and also act as an inhibitor of sirtuins.",122.12,"98-92-0",{"v":24,"d":"24.00"},196.53,{"v":24,"d":"24.00"},196.53,"http://selleckchem.com/products/Nicotinamide(Niacinamide).html","C6H6N2O","free base","Niacinamide, Vitamin PP, Nicotinic acid amide, Vitamin B3, NSC 27452,NSC 13128","NC(=O)C1=CC=CN=C1",-0.319,2,1,1]
["S1903","Diclofenac Sodium","e3","L8000-05","in 10mM DMSO","COX","Neuronal Signaling","Diclofenac Sodium (GP 45840) is a non-selective COX inhibitor with IC50 of 0.5 μg/ml and 0.5 μg/ml for COX-1 and -2 in intact cells, respectively, used as a nonsteroidal anti-inflammatory drug (NSAID) to relieve pain and reduce swelling in flammation.",318.13,"15307-79-6",{"v":64,"d":"64.00"},201.18,{"v":14,"d":"14.00"},44.01,"http://selleckchem.com/products/Diclofenac-sodium.html","C14H10Cl2NNaO2","Sodium Salt","GP 45840","[Na+].[O-]C(=O)CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1",2.899,0,1,4]
["S1907","Metronidazole","f3","L8000-05","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,DNA/RNA Synthesis","DNA Damage/DNA Repair","Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa.",171.15,"443-48-1",{"v":34,"d":"34.00"},198.66,"<1","N/A","http://selleckchem.com/products/Metronidazole(Flagyl).html","C6H9N3O3","free base","N/A","CC1=NC=C([N]1CCO)[N+]([O-])=O",-0.337,1,1,3]
["S1908","Flutamide","g3","L8000-05","in 10mM DMSO","Androgen Receptor","Endocrinology & Hormones","Flutamide (SCH-13521) is an antiandrogen drug, with its active metablolite binding at androgen receptor with Ki values of 55 nM, and primarily used to treat prostate cancer.",276.21,"13311-84-7",{"v":55,"d":"55.00"},199.12,"<1","N/A","http://selleckchem.com/products/Flutamide(Eulexin).html","C11H11F3N2O3","free base","SCH-13521","CC(C)C(=O)NC1=CC(=C(C=C1)[N+]([O-])=O)C(F)(F)F",2.916,1,1,4]
["S1909","Fluvastatin (XU-62-320) Sodium","h3","L8000-05","in 10mM DMSO","HMG-CoA Reductase","Metabolism","Fluvastatin Sodium (Vastin,XU-62-320) inhibits HMG-CoA reductase activity with IC50 of 8 nM in a cell-free assay.",433.45,"93957-55-2",{"v":87,"d":"87.00"},200.72,{"v":1,"d":"1.00"},2.31,"http://selleckchem.com/products/Fluvastatin-Sodium(Lescol).html","C24H25FNNaO4","Sodium","Vastin,XU-62-320","[Na+].CC(C)[N]1C2=C(C=CC=C2)C(=C1\\C=C\\C(O)CC(O)CC([O-])=O)C3=CC=C(F)C=C3",{"v":2.77,"d":"2.770"},0,2,8]
["S1910","Tioconazole","a4","L8000-05","in 10mM DMSO","Fungal","Microbiology","Tioconazole (UK-20349) is an antifungal medication with an average IC50 of 1.7 μM.",387.71,"65899-73-2",{"v":78,"d":"78.00"},201.18,"<1","N/A","http://selleckchem.com/products/tioconazole.html","C16H13Cl3N2OS","free base","UK-20349","ClC1=CC=C(C(C[N]2C=CN=C2)OCC3=C(Cl)SC=C3)C(=C1)Cl",4.437,2,0,6]
["S1913","Tropicamide","b4","L8000-05","in 10mM DMSO","AChR","Neuronal Signaling","Tropicamide(Ro 1-7683) is an anticholinergic and a muscarinic receptor subtype M4-preferring antagonist with IC50 of 8.0 nM.",284.35,"1508-75-4",{"v":57,"d":"57.00"},200.46,"<1","N/A","http://selleckchem.com/products/tropicamide.html","C17H20N2O2","free base","Ro 1-7683","CCN(CC1=CC=NC=C1)C(=O)C(CO)C2=CC=CC=C2",1.432,2,1,6]
["S1914","Pregnenolone","c4","L8000-05","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Pregnenolone(3β-Hydroxy-5-pregnen-20-one) is an endogenous steroid hormone, used in the treatment of fatigue, Alzheimer’s disease, trauma and injuries.",316.48,"145-13-1",{"v":22,"d":"22.00"},69.51,"<1","N/A","http://selleckchem.com/products/pregnenolone.html","C21H32O2","free base","3β-Hydroxy-5-pregnen-20-one","CC(=O)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C",3.624,1,1,1]
["S1915","Sulfamethoxazole","d4","L8000-05","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Sulfamethoxazole(Ro 4-2130) is a sulfonamide bacteriostatic antibiotic with an IC50 of 2.7 μM.",253.28,"723-46-6",{"v":51,"d":"51.00"},201.36,"<1","N/A","http://selleckchem.com/products/Sulfamethoxazole.html","C10H11N3O3S","free base","Ro 4-2130","CC1=CC(=NO1)N[S](=O)(=O)C2=CC=C(N)C=C2",0.709,4,2,3]
["S1916","Sulfisoxazole","e4","L8000-05","in 10mM DMSO","Bacterial","Microbiology","Sulfisoxazole (NU-445) is a sulfonamide antibacterial with an oxazole substituent.",{"v":267.3,"d":"267.30"},"127-69-5",{"v":53,"d":"53.00"},198.28,"<1","N/A","http://selleckchem.com/products/Sulfisoxazole.html","C11H13N3O3S","free base","NU-445","CC1=NOC(=C1C)N[S](=O)(=O)C2=CC=C(N)C=C2",0.918,4,2,3]
["S1917","Crystal Violet","f4","L8000-05","in 10mM DMSO","Dyes","Others","Crystal violet(Gentian Violet) is a triarylmethane dye.",407.98,"548-62-9",{"v":82,"d":"82.00"},200.99,{"v":14,"d":"14.00"},34.32,"http://selleckchem.com/products/Crystal-violet.html","C25H30ClN3","quaternary-N chloride salt","Gentian Violet","[Cl-].CN(C)C1=CC=C(C=C1)C(C2=CC=C(C=C2)N(C)C)=C3C=CC(C=C3)=[N+](C)C",{"v":2.25,"d":"2.250"},0,0,4]
["S1920","Haloperidol","g4","L8000-05","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Haloperidol (Haldol) is an antipsychotic and butyrophenone.",375.86,"52-86-8",{"v":75,"d":"75.00"},199.54,"<1","N/A","http://selleckchem.com/products/Haloperidol(Haldol).html","C21H23ClFNO2","free base","N/A","OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C3=CC=C(Cl)C=C3",3.887,1,0,6]
["S1933","Triamcinolone","h4","L8000-05","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Triamcinolone is a glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated.",394.43,"124-94-7",{"v":78,"d":"78.00"},197.75,"<1","N/A","http://selleckchem.com/products/Triamcinolone(Aristocort).html","C21H27FO6","free base","N/A","CC12CC(O)C3(F)C(CCC4=CC(=O)C=CC34C)C1CC(O)C2(O)C(=O)CO",0.422,2,3,2]
["S1934","Nystatin (Fungicidin)","a5","L8000-05","in 10mM DMSO","Antibiotics for Mammalian Cell Culture,Fungal","Microbiology","Nystatin(Fungicidin), which belongs to the polyene group of antimycotics, is frequently used as a topical agent in the treatment of oro-pharyngeal candidosis.",1056.24,"62997-67-5",{"v":19,"d":"19.00"},17.99,"<1","N/A","http://selleckchem.com/products/Nystatin(Mycostatin).html","C53H85NO20","free base","Fungicidin","CC1OC(=O)CC(O)CC(O)CC(O)CCC(O)C(O)CC2(O)CC(O)C(C(CC(OC3OC(C)C(O)C(N)C3O)/C=C/C=C/C=C/C=C/CC/C=C/C=C/C(C)C(O)C1C)O2)C(O)=O",-2.265,8,11,5]
["S1937","Isoniazid","b5","L8000-05","in 10mM DMSO","Fatty Acid Synthase","Metabolism","Isoniazid is a prodrug that blocks the action of fatty acid synthase by interacting with KatG , used for the prevention and treatment of tuberculosis.",137.14,"54-85-3",{"v":27,"d":"27.00"},196.88,{"v":27,"d":"27.00"},196.88,"http://selleckchem.com/products/Isoniazid(Tubizid).html","C6H7N3O","free base","N/A","NNC(=O)C1=CC=NC=C1",-0.811,2,2,1]
["S1941","Enalapril Maleate","c5","L8000-05","in 10mM DMSO","ACE,RAAS","Endocrinology & Hormones","Enalapril (MK-421) Maleate is an angiotensin-converting enzyme (ACE) inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure.",492.52,"76095-16-4",{"v":99,"d":"99.00"},201.01,"<1","N/A","http://selleckchem.com/products/Enalapril-maleate(Vasotec).html","C20H28N2O5.C4H4O4","Maleate","MK-421 Maleate","CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(O)=O.OC(=O)\\C=C/C(O)=O",-0.502,6,1,12]
["S1949","Menadione (NSC 4170)","d5","L8000-05","in 10mM DMSO","CDK,DNA/RNA Synthesis,phosphatase","Metabolism","Menadione (NSC 4170, Vitamin K3), a fat-soluble compound, is an inhibitor of Cdc25 phosphatase and mitochondrial DNA polymerase γ (pol γ), used as a nutritional supplement.",172.18,"58-27-5",{"v":34,"d":"34.00"},197.47,"<1","N/A","http://selleckchem.com/products/Menadione.html","C11H8O2","free base","Vitamin K3,NSC 4170","CC1=CC(=O)C2=CC=CC=C2C1=O",2.204,2,0,0]
["S1950","Metformin HCl","e5","L8000-05","in 10mM DMSO","Autophagy,Carbohydrate Metabolism,JNK,Mitophagy,p38 MAPK","Metabolism","Metformin HCl (1,1-Dimethylbiguanide HCl) decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis). Metformin promotes mitophagy in mononuclear cells. Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153.",165.62,"1115-70-4",{"v":33,"d":"33.00"},199.25,{"v":33,"d":"33.00"},199.25,"http://selleckchem.com/products/Metformin-hydrochloride(Glucophage).html","C4H11N5.HCl","Hydrochloride","1,1-Dimethylbiguanide HCl","Cl.CN(C)C(=N)NC(N)=N",{"v":-0.36,"d":"-0.360"},0,2,3]
["S1952","Methoxsalen","f5","L8000-05","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Methoxsalen (Xanthotoxin, NCI-C55903) is a naturally occurring photoactive substance found in the seeds of the Ammi majus (Umbelliferae) plant, used in the diagnosis and treatment of psoriasis; A CYP2A5/6 inhibitor.",216.19,"298-81-7",{"v":43,"d":"43.00"},{"v":198.9,"d":"198.90"},"<1","N/A","http://selleckchem.com/products/Methoxsalen(Oxsoralen).html","C12H8O4","free base","Xanthotoxin, NCI-C55903","COC1=C2OC=CC2=CC3=C1OC(=O)C=C3",2.187,4,0,1]
["S1957","Sulfamethizole","g5","L8000-05","in 10mM DMSO","Bacterial","Microbiology","Sulfamethizole is a sulfathiazole antibacterial agent.",270.33,"144-82-1",{"v":54,"d":"54.00"},199.76,"<1","N/A","http://selleckchem.com/products/Sulfamethizole(Proklar).html","C9H10N4O2S2","free base","N/A","CC1=NN=C(N[S](=O)(=O)C2=CC=C(N)C=C2)S1",0.305,4,2,3]
["S1959","Tolfenamic Acid","h5","L8000-05","in 10mM DMSO","COX","Neuronal Signaling","Tolfenamic Acid(Clotam) is a COX-2 inhibitor with IC50 of 0.2 μM.",{"v":261.7,"d":"261.70"},"13710-19-5",{"v":52,"d":"52.00"},{"v":198.7,"d":"198.70"},"<1","N/A","http://selleckchem.com/products/tolfenamic-acid.html","C14H12ClNO2","free base","Clotam","CC1=C(Cl)C=CC=C1NC2=C(C=CC=C2)C(O)=O",{"v":4.16,"d":"4.160"},1,1,3]
["S1965","Primidone","a6","L8000-05","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Primidone (NCI-C56360) is an anticonvulsant of the pyrimidinedione class.",218.25,"125-33-7",{"v":44,"d":"44.00"},{"v":201.6,"d":"201.60"},"<1","N/A","http://selleckchem.com/products/Primidone(Mysoline).html","C12H14N2O2","free base","NCI-C56360","CCC1(C(=O)NCNC1=O)C2=CC=CC=C2",0.931,2,2,2]
["S1969","Nefiracetam","b6","L8000-05","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Nefiracetam (DZL 221) is a GABAergic, cholinergic, and monoaminergic neuronal system enhancer for Ro 5-4864-induced convulsions. Phase 2.",{"v":246.3,"d":"246.30"},"77191-36-7",{"v":49,"d":"49.00"},198.94,{"v":5,"d":"5.00"},{"v":20.3,"d":"20.30"},"http://selleckchem.com/products/Nefiracetam(Translon).html","C14H18N2O2","free base","DZL 221","CC1=CC=CC(=C1NC(=O)CN2CCCC2=O)C",1.443,2,1,3]
["S1971","Nicorandil","c6","L8000-05","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Nicorandil (SG-75) is a potassium channel activator, and stimulates guanylate cyclase to increase formation of cyclic GMP (cGMP).",211.17,"65141-46-0",{"v":42,"d":"42.00"},198.89,{"v":17,"d":"17.00"},{"v":80.5,"d":"80.50"},"http://selleckchem.com/products/Nicorandil(Ikorel).html","C8H9N3O4","free base","SG-75","[O-][N+](=O)OCCNC(=O)C1=CC=CN=C1",1.758,3,1,5]
["S1972","Tamoxifen (ICI 46474) Citrate","d6","L8000-05","in 10mM DMSO","Apoptosis related,Autophagy,Estrogen/progestogen Receptor,HSP (HSP90)","Endocrinology & Hormones","Tamoxifen Citrate (Istubal,ICI 46474 Citrate) is a selective estrogen receptor modulator (SERM). Tamoxifen Citrate is also a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen induces apoptosis and autophagy.",563.64,"54965-24-1",{"v":100,"d":"100.00"},177.42,"<1","N/A","http://selleckchem.com/products/Tamoxifen-Citrate(Nolvadex).html","C26H29NO.C6H8O7","Citrate","Istubal,ICI 46474 Citrate","CC/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(OCCN(C)C)C=C3.OC(=O)CC(O)(CC(O)=O)C(O)=O",1.966,4,0,13]
["S1973","Cyclocytidine HCl","e6","L8000-05","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Cyclocytidine (NSC 145668) is the prodrug of cytarabine, which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia.",261.66,"10212-25-6",{"v":10,"d":"10.00"},38.22,{"v":44,"d":"44.00"},168.16,"http://selleckchem.com/products/cyclocytidine-hcl.html","C9H12ClN3O4","Hydrochloride","NSC 145668 HCl","Cl.OCC1OC2C(OC3=NC(=N)C=CN23)C1O",-1.395,3,2,1]
["S1975","Aripiprazole","f6","L8000-05","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Aripiprazole (OPC-14597) is a novel atypical antipsychotic drug that is reported to be a high-affinity 5-HT receptor partial agonist.",448.39,"129722-12-9",{"v":90,"d":"90.00"},200.72,"<1","N/A","http://selleckchem.com/products/aripiprazole-abilify.html","C23H27Cl2N3O2","free base","OPC-14597","ClC1=CC=CC(=C1Cl)N2CCN(CCCCOC3=CC=C4CCC(=O)NC4=C3)CC2",4.998,2,1,7]
["S1978","Methscopolamine","g6","L8000-05","in 10mM DMSO","AChR","Neuronal Signaling","Methscopolamine is a muscarinic acetylcholine receptor blocker.",398.29,"155-41-9",{"v":79,"d":"79.00"},198.35,{"v":67,"d":"67.00"},168.22,"http://selleckchem.com/products/Methscopolamine-bromide(Pamine).html","C18H24BrNO4","quaternary-N bromide salt","N/A","[Br-].C[N+]1(C)C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",-2.949,3,1,5]
["S1979","Amiodarone (NSC 85442) HCl","h6","L8000-05","in 10mM DMSO","Autophagy,Potassium Channel","Transmembrane Transporters","Amiodarone (NSC 85442,Amiodar,Amiodarone hydrochloride,Nexterone) HCl is a sodium/potassium-ATPase inhibitor and an autophagy activator, used to treat various types of cardiac dysrhythmias.",681.77,"19774-82-4",{"v":23,"d":"23.00"},33.74,"<1","N/A","http://selleckchem.com/products/amiodarone-hcl.html","C25H29I2NO3.HCl","Hydrochloride","Amiodar,Amiodarone hydrochloride,Nexterone","Cl.CCCCC1=C(C(=O)C2=CC(=C(OCCN(CC)CC)C(=C2)I)I)C3=C(O1)C=CC=C3",{"v":7.62,"d":"7.620"},3,0,11]
["S1990","Capsaicin(Vanilloid)","a7","L8000-05","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Capsaicin (Qutenza, Vanilloid) is an active component of chili peppers, which are plants belonging to the genus Capsicum.Capsaici is a TRPV1 agonist with an EC50 of 0.29 μM in HEK293 cells.",305.41,"404-86-4",{"v":61,"d":"61.00"},199.73,"<1","N/A","http://selleckchem.com/products/capsaicin.html","C18H27NO3","free base","Qutenza, Vanilloid","COC1=C(O)C=CC(=C1)CNC(=O)CCCC\\C=C\\C(C)C",{"v":3.91,"d":"3.910"},2,2,9]
["S1992","Fluticasone propionate","b7","L8000-05","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Fluticasone Propionate (CCI-187881) is a synthetic glucocorticoid, used to treat non-allergic and allergic rhinitis.",500.57,"80474-14-2",{"v":100,"d":"100.00"},199.77,"<1","N/A","http://selleckchem.com/products/fluticasone-propionate-Flonase-Veramyst.html","C25H31F3O5S","free base","CCI-187881","CCC(=O)OC1(C(C)CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)SCF",4.086,4,1,6]
["S2003","Maraviroc (UK-427857)","c7","L8000-05","in 10mM DMSO","CCR,HIV","Microbiology","Maraviroc (Celsentri,UK-427857) is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM in cell-free assays, respectively. Maraviroc is used in the treatment of HIV infection.",513.67,"376348-65-1",{"v":100,"d":"100.00"},194.68,"<1","N/A","http://selleckchem.com/products/Maraviroc.html","C29H41F2N5O","free base","Celsentri,UK-427857","CC(C)C1=NN=C(C)[N]1C2CC3CCC(C2)N3CCC(NC(=O)C4CCC(F)(F)CC4)C5=CC=CC=C5",3.921,3,1,8]
["S2006","Pyrimethamine","d7","L8000-05","in 10mM DMSO","DHFR","Metabolism","Pyrimethamine(RP 4753) is a dihydrofolate reductase (DHFR) inhibitor, used as an antimalarial drug.",248.71,"58-14-0",{"v":10,"d":"10.00"},40.21,"<1","N/A","http://selleckchem.com/products/Pyrimethamine.html","C12H13ClN4","free base","RP 4753","CCC1=NC(=NC(=C1C2=CC=C(Cl)C=C2)N)N",{"v":2.75,"d":"2.750"},2,2,2]
["S2007","Sulindac","e7","L8000-05","in 10mM DMSO","COX","Neuronal Signaling","Sulindac(MK-231) is a non-steroidal COX inhibitor, which potently inhibits prostaglandin synthesis, used in the treatment of acute or chronic inflammatory conditions.",356.41,"38194-50-2",{"v":71,"d":"71.00"},199.21,"<1","N/A","http://selleckchem.com/products/Sulindac(Clinoril).html","C20H17FO3S","free base","MK-231","CC1=C(CC(O)=O)C2=C(C=CC(=C2)F)\\C1=C/C3=CC=C(C=C3)[S](C)=O",3.639,2,0,4]
["S2015","Suplatast Tosylate","f7","L8000-05","in 10mM DMSO","Interleukins","Immunology & Inflammation","Suplatast Tosylate (IPD-1151T, Suplatast Tosilate) is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM.",499.64,"94055-76-2",{"v":100,"d":"100.00"},200.14,{"v":100,"d":"100.00"},200.14,"http://selleckchem.com/products/suplatast-tosilate.html","C23H33NO7S2","Tosylate","IPD-1151T, Suplatast Tosilate","CCOCC(O)COC1=CC=C(NC(=O)CC[S+](C)C)C=C1.CC2=CC=C(C=C2)[S]([O-])(=O)=O",0.877,3,2,11]
["S2017","Benidipine HCl","g7","L8000-05","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Benidipine HCl (KW-3049,(±)- Benidipine) is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker.",542.02,"91599-74-5",{"v":8,"d":"8.00"},14.76,"<1","N/A","http://selleckchem.com/products/benidipine-hydrochloride.html","C28H31N3O6.HCl","Hydrochloride","KW-3049,(±)- Benidipine","Cl.COC(=O)C1=C(C)NC(=C(C1C2=CC(=CC=C2)[N+]([O-])=O)C(=O)OC3CCCN(C3)CC4=CC=CC=C4)C",{"v":4.36,"d":"4.360"},4,1,9]
["S2020","Formoterol Hemifumarate","h7","L8000-05","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Formoterol Hemifumarate (Eformoterol, CGP 25827A, NSC 299587, YM 08316,Formoterol fumarate) is a potent, selective and long-acting β2-adrenoceptor agonist used in the management of asthma and chronic obstructive pulmonary disease(COPD).",{"v":402.4,"d":"402.40"},"43229-80-7",{"v":80,"d":"80.00"},198.81,"<1","N/A","http://selleckchem.com/products/formoterol-hemifumarate.html","C19H24N2O4.1/2C4H4O4","Hemifumarate","Eformoterol, CGP 25827A, NSC 299587, YM 08316,Formoterol fumarate","COC1=CC=C(CC(C)NCC(O)C2=CC=C(O)C(=C2)NC=O)C=C1.COC3=CC=C(CC(C)NCC(O)C4=CC=C(O)C(=C4)NC=O)C=C3.OC(=O)\\C=C\\C(O)=O",-1.526,6,8,18]
["S2024","Ketotifen Fumarate","a8","L8000-05","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Ketotifen Fumarate(HC 20511 fumarate) is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer.",{"v":425.5,"d":"425.50"},"34580-14-8",{"v":8,"d":"8.00"},{"v":18.8,"d":"18.80"},"<1","N/A","http://selleckchem.com/products/ketotifen-fumarate-zaditor.html","C19H19NOS.C4H4O4","Fumarate","HC 20511 fumarate","CN1CCC(CC1)=C2C3=C(CC(=O)C4=C2C=CS4)C=CC=C3.OC(=O)\\C=C\\C(O)=O",0.772,3,0,2]
["S2025","Urapidil HCl","b8","L8000-05","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Urapidil HCl is a hydrochloride salt form of urapidil which is α1-adrenoceptor antagonist and 5-HT1A receptor agonist with pIC50 of 6.13 and 6.4 respectively.",423.94,"64887-14-5",{"v":24,"d":"24.00"},56.61,{"v":85,"d":"85.00"},{"v":200.5,"d":"200.50"},"http://selleckchem.com/products/urapidil-hydrochloride.html","C20H29N5O3.HCl","Hydrochloride","N/A","Cl.COC1=CC=CC=C1N2CCN(CCCNC3=CC(=O)N(C)C(=O)N3C)CC2",1.808,3,1,7]
["S2028","Diclazuril","c8","L8000-05","in 10mM DMSO","Parasite","Microbiology","Diclazuril(R-64433) is an anti-coccidial drug.",407.64,"101831-37-2",{"v":16,"d":"16.00"},39.25,"<1","N/A","http://selleckchem.com/products/diclazuril.html","C17H9Cl3N4O2","free base","R-64433","ClC1=CC=C(C=C1)C(C#N)C2=C(Cl)C=C(C=C2Cl)N3N=CC(=O)NC3=O",4.191,3,1,3]
["S2029","Uridine","d8","L8000-05","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Uridine (NSC 20256,β-Uridine, Uridin) is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond.",{"v":244.2,"d":"244.20"},"58-96-8",{"v":49,"d":"49.00"},200.66,{"v":49,"d":"49.00"},200.66,"http://selleckchem.com/products/uridine.html","C9H12N2O6","free base","NSC 20256,β-Uridine, Uridin","OCC1OC(C(O)C1O)N2C=CC(=O)NC2=O",-2.451,3,4,2]
["S2032","Rebamipide","e8","L8000-05","in 10mM DMSO","CCK receptor","GPCR & G Protein","Rebamipide (OPC-12759,Proamipide) is a cholecystokinin type 1 (CCK1) receptor inhibitor for inhibiting [125I]BH-CCK-8S with IC50 of 37.7 μM.",370.79,"90098-04-7",{"v":74,"d":"74.00"},199.57,"<1","N/A","http://selleckchem.com/products/rebamipide.html","C19H15ClN2O4","free base","OPC-12759,Proamipide","OC(=O)C(CC1=CC(=O)NC2=C1C=CC=C2)NC(=O)C3=CC=C(Cl)C=C3",2.606,3,2,5]
["S2037","Candesartan Cilexetil","f8","L8000-05","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist with IC50 of 0.26 nM, used in the treatment of hypertension.",610.66,"145040-37-5",{"v":122,"d":"122.00"},199.78,"<1","N/A","http://selleckchem.com/products/Candesartan-cilexetil-Atacand.html","C33H34N6O6","free base","TCV-116","CCOC1=NC2=C([N]1CC3=CC=C(C=C3)C4=C(C=CC=C4)C5=NN=N[NH]5)C(=CC=C2)C(=O)OC(C)OC(=O)OC6CCCCC6",6.913,10,1,13]
["S2038","Phentolamine Mesylate","g8","L8000-05","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Phentolamine Mesylate(Phentolamine methanesulfonate) is a reversible and nonselective alpha-adrenergic receptor antagonist, used for the prevention or control of hypertensive episodes.",377.46,"65-28-1",{"v":76,"d":"76.00"},201.35,{"v":76,"d":"76.00"},201.35,"http://selleckchem.com/products/phentolamine-mesilate.html","C17H19N3O.CH4O3S","Mesylate","Phentolamine methanesulfonate","CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.C[S](O)(=O)=O",2.555,1,2,4]
["S2040","Nimesulide","h8","L8000-05","in 10mM DMSO","COX","Neuronal Signaling","Nimesulide is a relatively COX-2 selective inhibitor with IC50 of 26 μM.",308.31,"51803-78-2",{"v":62,"d":"62.00"},{"v":201.1,"d":"201.10"},"<1","N/A","http://selleckchem.com/products/Nimesulide.html","C13H12N2O5S","free base","N/A","C[S](=O)(=O)NC1=C(OC2=CC=CC=C2)C=C(C=C1)[N+]([O-])=O",2.195,3,1,5]
["S2042","Cyproterone Acetate","a9","L8000-05","in 10mM DMSO","Androgen Receptor","Endocrinology & Hormones","Cyproterone acetate is an androgen receptor (AR) antagonist with IC50 of 7.1 nM, as well as a weak progesterone receptor agonist with weak pro-gestational and glucocorticoid activity.",416.94,"427-51-0",{"v":83,"d":"83.00"},199.07,"<1","N/A","http://selleckchem.com/products/cyproterone-acetate.html","C24H29ClO4","free base","N/A","CC(=O)OC1(CCC2C3C=C(Cl)C4=CC(=O)C5CC5C4(C)C3CCC12C)C(C)=O",3.314,4,0,3]
["S2045","Doxifluridine","b9","L8000-05","in 10mM DMSO","Phosphorylase","Metabolism","Doxifluridine (5'-DFUR, AMC 0101) is an oral prodrug that is converted to the cytotoxic agent 5-fluorouracil (5-FU).",246.19,"3094-09-5",{"v":49,"d":"49.00"},199.03,{"v":49,"d":"49.00"},199.03,"http://selleckchem.com/products/doxifluridine.html","C9H11FN2O5","free base","5'-DFUR, AMC 0101","CC1OC(C(O)C1O)N2C=C(F)C(=O)NC2=O",-1.653,3,3,1]
["S2046","Pioglitazone HCl","c9","L8000-05","in 10mM DMSO","Ferroptosis,P450 (e.g. CYP17),PPAR","Metabolism","Pioglitazone HCl (AD-4833, U-72107E) is an inhibitor of cytochrome P450 (CYP)2C8 and CYP3A4 enzymes. Pioglitazone HCl inhibits CYP2C8, CYP3A4 and CYP2C9 with Ki of 1.7 μM, 11.8 μM and 32.1 μM, respectively. Pioglitazone HCl is also a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist with EC50 of 0.93 μM and 0.99 μM for human PPARγ and mouse PPARγ, respectively. Pioglitazone HCl inhibits mitochondrial iron uptake, lipid peroxidation, and subsequent ferroptosis.",{"v":392.9,"d":"392.90"},"112529-15-4",{"v":79,"d":"79.00"},201.07,"<1","N/A","http://selleckchem.com/products/pioglitazone-hydrochloride-actos.html","C19H20N2O3S.HCl","Hydrochloride","AD-4833, U-72107E","Cl.CCC1=CC=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)N=C1",4.289,4,1,7]
["S2051","Captopril","d9","L8000-05","in 10mM DMSO","ACE,RAAS","Endocrinology & Hormones","Captopril (SQ 14225,Capoten) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.",217.29,"62571-86-2",{"v":43,"d":"43.00"},197.89,{"v":2,"d":"2.00"},{"v":9.2,"d":"9.20"},"http://selleckchem.com/products/captopril-capoten.html","C9H15NO3S","free base","SQ 14225,Capoten","CC(CS)C(=O)N1CCCC1C(O)=O",0.667,2,0,3]
["S2053","Cytidine","e9","L8000-05","in 10mM DMSO","Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA.",243.22,"65-46-3",{"v":49,"d":"49.00"},201.46,{"v":49,"d":"49.00"},201.46,"http://selleckchem.com/products/cytidine.html","C9H13N3O5","free base","N/A","NC1=NC(=O)N(C=C1)C2OC(CO)C(O)C2O",-2.396,3,4,2]
["S2055","Gimeracil","f9","L8000-05","in 10mM DMSO","Dehydrogenase","Metabolism","Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase, which inhibits the early step in homologous recombination for double strand breaks repair.",145.54,"103766-25-2",{"v":29,"d":"29.00"},199.26,"<1","N/A","http://selleckchem.com/products/gimeracil.html","C5H4ClNO2","free base","N/A","OC1=CC(=O)NC=C1Cl",-0.493,1,2,0]
["S2057","Cyclophosphamide (NSC-26271) Monohydrate","g9","L8000-05","in 10mM DMSO","DNA alkylator","DNA Damage/DNA Repair","Cyclophosphamide (NSC-26271, Cytoxan) Monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA, shown to crosslink DNA, causing strand breakage and inducing mutations.",{"v":279.1,"d":"279.10"},"6055-19-2",{"v":55,"d":"55.00"},197.06,{"v":7,"d":"7.00"},25.08,"http://selleckchem.com/products/cyclophosphamide-monohydrate.html","C7H15Cl2N2O2P.H2O","Monohydrate","Cytoxan Monohydrate","O.ClCCN(CCCl)[P]1(=O)NCCCO1",-0.063,2,1,5]
["S2058","Tolnaftate","h9","L8000-05","in 10mM DMSO","Fungal","Microbiology","Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.",307.41,"2398-96-1",{"v":62,"d":"62.00"},201.69,"<1","N/A","http://selleckchem.com/products/tolnaftate.html","C19H17NOS","free base","N/A","CN(C(=S)OC1=CC=C2C=CC=CC2=C1)C3=CC(=CC=C3)C",6.289,1,0,4]
["S2059","Terazosin HCl Dihydrate","a10","L8000-05","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Terazosin HCl is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH).",459.92,"70024-40-7",{"v":26,"d":"26.00"},56.53,"<1","N/A","http://selleckchem.com/products/terazosin-hydrochloride-hytrin.html","C19H25N5O4.HCl.2H2O","HCl & Dihydrate","N/A","O.O.Cl.COC1=CC2=C(C=C1OC)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N",1.348,6,1,4]
["S2061","Lovastatin (MK-803)","b10","L8000-05","in 10mM DMSO","Autophagy,HMG-CoA Reductase","Metabolism","Lovastatin (MK-803, Mevinolin,Mevacor) is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM in a cell-free assay, used for lowering cholesterol (hypolipidemic agent). Lovastatin triggers autophagy.",404.54,"75330-75-5",{"v":8,"d":"8.00"},19.78,"<1","N/A","http://selleckchem.com/products/lovastatin-mevacor.html","C24H36O5","free base","Mevinolin,Mevacor","CCC(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C12",4.218,4,1,7]
["S2064","Balofloxacin","c10","L8000-05","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Balofloxacin (Q-35,Q-roxin) is a quinolone antibiotic, inhibiting the synthesis of bacterial DNA by interference with the enqyme DNA gyrase.",389.42,"127294-70-6",{"v":5,"d":"5.00"},12.84,"<1","N/A","http://selleckchem.com/products/balofloxacin.html","C20H24FN3O4","free base","Q-35,Q-roxin","CNC1CCCN(C1)C2=C(OC)C3=C(C=C2F)C(=O)C(=CN3C4CC4)C(O)=O",-0.615,3,1,5]
["S2065","Lafutidine","d10","L8000-05","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Lafutidine (FRG-8813), a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.",431.55,"118288-08-7",{"v":86,"d":"86.00"},199.28,"<1","N/A","http://selleckchem.com/products/lafutidine.html","C22H29N3O4S","free base","FRG-8813","O=C(C[S](=O)CC1=CC=CO1)NC\\C=C/COC2=CC(=CC=N2)CN3CCCCC3",1.987,5,1,11]
["S2067","Ozagrel HCl","e10","L8000-05","in 10mM DMSO","P450 (e.g. CYP17),Prostaglandin Receptor","Metabolism","Ozagrel HCl (OKY-046) is a selective <n>thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.",264.71,"78712-43-3",{"v":52,"d":"52.00"},196.44,{"v":52,"d":"52.00"},196.44,"http://selleckchem.com/products/ozagrel-hydrochloride.html","C13H12N2O2.HCl","HCl","OKY-046 HCl","Cl.OC(=O)/C=C/C1=CC=C(C[N]2C=CN=C2)C=C1",1.986,2,0,4]
["S2069","Argatroban (MCI-9038)","f10","L8000-05","in 10mM DMSO","Thrombin","Proteases","Argatroban (MCI-9038) is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant.",508.63,"74863-84-6",{"v":9,"d":"9.00"},17.69,"<1","N/A","http://selleckchem.com/products/argatroban.html","C23H36N6O5S","free base","MCI-9038","CC1CCN(C(C1)C(O)=O)C(=O)C(CCCNC(N)=N)N[S](=O)(=O)C2=CC=CC3=C2NCC(C)C3",1.266,4,4,10]
["S2072","Seratrodast(AA-2414)","g10","L8000-05","in 10mM DMSO","Prostaglandin Receptor","Metabolism","Seratrodast (AA-2414, ABT-001) is a potent and selective thromboxane A2 receptor (TP) antagonist which is used primarily in the treatment of asthma and used as anti-inflammatory agent.",354.44,"112665-43-7",{"v":71,"d":"71.00"},200.32,"<1","N/A","http://www.selleck.cn/products/seratrodast.html","C22H26O4","Free Base","ABT-001","CC1=C(C)C(=O)C(=C(C)C1=O)C(CCCCCC(O)=O)C2=CC=CC=C2",5.216,3,0,8]
["S2077","Atorvastatin Calcium","h10","L8000-05","in 10mM DMSO","Apoptosis related,Autophagy,HMG-CoA Reductase","Metabolism","Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. Atorvastatin Calcium induces apoptosis and autophagy.",1155.34,"134523-03-8",{"v":100,"d":"100.00"},86.55,"<1","N/A","http://selleckchem.com/products/atorvastatin-calcium-lipitor.html","2(C33H34FN2O5).Ca","Calcium","N/A","[Ca++].CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C([N]1CCC(O)CC(O)CC([O-])=O)C3=CC=C(F)C=C3)C4=CC=CC=C4.CC(C)C5=C(C(=O)NC6=CC=CC=C6)C(=C([N]5CCC(O)CC(O)CC([O-])=O)C7=CC=C(F)C=C7)C8=CC=CC=C8",8.163,2,6,24]
["S2078","Famotidine","a11","L8000-05","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Famotidine (MK208) is a histamine H2–receptor antagonist with IC50 of 0.6 mM, commonly used to treat heartburn, GERD, ulcers, and other digestive conditions.",337.45,"76824-35-6",{"v":67,"d":"67.00"},198.55,"<1","N/A","http://selleckchem.com/products/famotidine-pepcid.html","C8H15N7O2S3","free base","MK208","NC(=N)NC1=NC(=CS1)CSCCC(=N)N[S](N)(=O)=O",-1.328,3,4,9]
["S2080","Clevidipine Butyrate","b11","L8000-05","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Clevidipine Butyrate(Cleviprex) is a dihydropyridine calcium channel blocker,  uses as an agent for the reduction of blood pressure.",456.32,"167221-71-8",{"v":91,"d":"91.00"},199.42,"<1","N/A","http://selleckchem.com/products/cleviprex-clevidipine.html","C21H23Cl2NO6","free base","Cleviprex","CCCC(=O)OCOC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2Cl)Cl)C(=O)OC)C",4.145,6,1,10]
["S2082","Adiphenine HCl","c11","L8000-05","in 10mM DMSO","AChR","Neuronal Signaling","Adiphenine HCl(NSC 129224) is a nicotinic receptor inhibitor, used as an antispasmodic drug.",347.88,"50-42-0",{"v":30,"d":"30.00"},86.24,{"v":70,"d":"70.00"},201.22,"http://selleckchem.com/products/adiphenine-hcl.html","C20H25NO2.HCl","HCl","NSC 129224","Cl.CCN(CC)CCOC(=O)C(C1=CC=CC=C1)C2=CC=CC=C2",4.433,2,0,9]
["S2086","Ivabradine HCl","d11","L8000-05","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Ivabradine HCl (S 16257-2,S-18982 D6 hydrochloride), a new If inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent.",505.05,"148849-67-6",{"v":101,"d":"101.00"},199.98,{"v":82,"d":"82.00"},162.36,"http://selleckchem.com/products/ivabradine-hcl-procoralan.html","C27H36N2O5.HCl","HCl","S 16257-2,S-18982 D6 hydrochloride","Cl.COC1=CC2=C(CC(=O)N(CCCN(C)CC3CC4=CC(=C(OC)C=C34)OC)CC2)C=C1OC",3.753,5,0,10]
["S2087","Rivastigmine Tartrate","e11","L8000-05","in 10mM DMSO","AChR","Neuronal Signaling","Rivastigmine Tartrate (ENA 713) is a cholinesterase inhibitor with IC50 of 5.5 μM, and used as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease.",400.42,"129101-54-8",{"v":42,"d":"42.00"},104.89,{"v":80,"d":"80.00"},199.79,"http://selleckchem.com/products/rivastigmine-tartrate-exelon.html","C14H22N2O2.C4H6O6","Tartrate","ENA 713","CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C.OC(C(O)C(O)=O)C(O)=O",-2.099,4,2,8]
["S2090","Dexmedetomidine HCl","f11","L8000-05","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Dexmedetomidine HCl((+)-Medetomidine Hydrochloride) is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.",236.74,"145108-58-3",{"v":48,"d":"48.00"},202.75,"<1","N/A","http://selleckchem.com/products/dexmedetomidine-hcl-precedex.html","C13H16N2.HCl","HCl","(+)-Medetomidine Hydrochloride","Cl.CC(C1=CN=C[NH]1)C2=CC=CC(=C2C)C",3.378,1,1,2]
["S2096","Almotriptan Malate","g11","L8000-05","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Almotriptan Malate (LAS 31416) is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults.",469.55,"181183-52-8",{"v":94,"d":"94.00"},200.19,"<1","N/A","http://selleckchem.com/products/almotriptan-malate-axert.html","C17H25N3O2S.C4H6O5","Malate","LAS 31416","CN(C)CCC1=C[NH]C2=CC=C(C[S](=O)(=O)N3CCCC3)C=C12.OC(CC(O)=O)C(O)=O",-1.943,4,2,9]
["S2098","Bexarotene (LGD1069)","h11","L8000-05","in 10mM DMSO","Retinoid Receptor","Metabolism","Bexarotene (Targretin, LGD1069) is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.",{"v":348,"d":"348.00"},"153559-49-0",{"v":8,"d":"8.00"},22.99,"<1","N/A","http://selleckchem.com/products/bexarotene.html","C24H28O2","free base","Targretin","CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(O)=O)C(C)(C)CCC2(C)C",6.405,1,0,3]
["S2099","Temocapril HCl","a2","L8000-06","in 10mM DMSO","ACE,RAAS","Endocrinology & Hormones","Temocapril HCl (CS-622) is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.",513.07,"110221-44-8",{"v":103,"d":"103.00"},200.75,"<1","N/A","http://selleckchem.com/products/temocapril-hcl.html","C23H28N2O5S2.HCl","Hydrochloride","CS-622 HCl","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC2CSC(CN(CC(O)=O)C2=O)C3=CC=CS3",0.787,4,1,11]
["S2101","Gabexate Mesylate","b2","L8000-06","in 10mM DMSO","Serine Protease","Proteases","Gabexate Mesylate(FOY) is a serine protease inhibitor with IC50 of 0.19 μM which is used therapeutically in the treatment of pancreatitis and disseminated intravascular coagulation.",417.48,"56974-61-9",{"v":83,"d":"83.00"},198.81,{"v":12,"d":"12.00"},28.74,"http://selleckchem.com/products/gabexate-mesylate.html","C16H23N3O4.CH4O3S","Mesylate","FOY","CCOC(=O)C1=CC=C(OC(=O)CCCCCNC(N)=N)C=C1.C[S](O)(=O)=O",1.774,4,2,12]
["S2102","Rasagiline Mesylate","c2","L8000-06","in 10mM DMSO","MAO","Metabolism","Rasagiline Mesylate (TVP-1012,(R)-AGN1135 mesylate,TVP1012 mesylate) is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.",267.34,"161735-79-1",{"v":53,"d":"53.00"},198.25,{"v":53,"d":"53.00"},198.25,"http://selleckchem.com/products/rasagiline-mesylate.html","C12H13N.CH4O3S","Mesylate","TVP-1012,(R)-AGN1135 mesylate,TVP1012 mesylate","C[S](O)(=O)=O.C#CCNC1CCC2=CC=CC=C12",2.705,0,1,2]
["S2103","Naltrexone HCl","d2","L8000-06","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","Naltrexone HCl(PTI-901) is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence.",377.86,"16676-29-2",{"v":14,"d":"14.00"},37.05,{"v":14,"d":"14.00"},37.05,"http://selleckchem.com/products/naltrexone-hcl.html","C20H23NO4.HCl","Hydrochloride","PTI-901","Cl.OC1=CC=C2CC3N(CCC45C(OC1=C24)C(=O)CCC35O)CC6CC6",2.039,2,1,2]
["S2105","Pantoprazole","e2","L8000-06","in 10mM DMSO","ATPase,Proton Pump","Transmembrane Transporters","Pantoprazole (SKF96022, BY-1023) is a proton pump inhibitor drug that inhibits gastric acid secretion. It works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid.",383.37,"102625-70-7",{"v":76,"d":"76.00"},198.24,"<1","N/A","http://selleckchem.com/products/pantoprazole-protonix.html","C16H15F2N3O4S","free base","SKFSKF96022, BY-1023","COC1=C(OC)C(=NC=C1)C[S](=O)C2=NC3=CC=C(OC(F)F)C=C3[NH]2",2.737,6,1,7]
["S2108","Flunixin Meglumin","f2","L8000-06","in 10mM DMSO","COX","Neuronal Signaling","Flunixin Meglumin(Banamine) is a potent inhibitor of the enzyme cyclooxygenase (COX) used as analgesic agent with anti-inflammatory and antipyretic activity.",491.46,"42461-84-7",{"v":98,"d":"98.00"},199.41,{"v":98,"d":"98.00"},199.41,"http://selleckchem.com/products/flunixin-meglumin.html","C14H11F3N2O2.C7H17NO5","Meglumin","Banamine","CNCC(O)C(O)C(O)C(O)CO.CC1=C(C=CC=C1NC2=NC=CC=C2C(O)=O)C(F)(F)F",-1.676,2,7,10]
["S2109","Imidapril HCl","g2","L8000-06","in 10mM DMSO","ACE,RAAS","Endocrinology & Hormones","Imidapril HCl(TA-6366) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.",441.91,"89396-94-1",{"v":88,"d":"88.00"},199.14,{"v":54,"d":"54.00"},{"v":122.2,"d":"122.20"},"http://selleckchem.com/products/imidapril-tanatril.html","C20H27N3O6.HCl","Hydrochloride","TA-6366","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C(CN(C)C2=O)C(O)=O",-1.197,5,1,10]
["S2111","Lapatinib (GW-572016)","h2","L8000-06","in 10mM DMSO","Autophagy,EGFR,Ferroptosis,HER2","Protein Tyrosine Kinase","Lapatinib (GW-572016, GSK572016, GW2016), used in the form of Lapatinib Ditosylate, is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively. Lapatinib induces ferroptosis and autophagic cell death.",581.06,"231277-92-2",{"v":100,"d":"100.00"},{"v":172.1,"d":"172.10"},"<1","N/A","http://selleckchem.com/products/lapatinib.html","C29H26ClFN4O4S","free base","GSK572016, GW2016","C[S](=O)(=O)CCNCC1=CC=C(O1)C2=CC=C3N=CN=C(NC4=CC=C(OCC5=CC=CC(=C5)F)C(=C4)Cl)C3=C2",6.041,6,2,11]
["S2113","Cisatracurium Besylate","a3","L8000-06","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Cisatracurium Besylate(51W89) is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.",1243.48,"96946-42-8",{"v":249,"d":"249.00"},200.24,{"v":47,"d":"47.00"},{"v":37.8,"d":"37.80"},"http://selleckchem.com/products/cisatracurium-besylate-nimbex.html","C53H72N2O12.2C6H5O3S","Besylate","51W89","COC1=CC=C(CC2C3=CC(=C(OC)C=C3CC[N+]2(C)CCC(=O)OCCCCCOC(=O)CC[N+]4(C)CCC5=CC(=C(OC)C=C5C4CC6=CC=C(OC)C(=C6)OC)OC)OC)C=C1OC.[O-][S](=O)(=O)C7=CC=CC=C7.[O-][S](=O)(=O)C8=CC=CC=C8",3.646,12,0,28]
["S2114","Dronedarone HCl","b3","L8000-06","in 10mM DMSO","Calcium Channel,Potassium Channel,Sodium Channel","Transmembrane Transporters","Dronedarone HCl (SR33589) is a multichannel blocker targeting potassium channel, sodium channel and calcium channel, used as an antiarrhythmic drug for treatment of atrial fibrillation (AF).",593.22,"141625-93-6",{"v":80,"d":"80.00"},134.86,"<1","N/A","http://selleckchem.com/products/dronedarone-hcl-multaq.html","C31H44N2O5S.HCl","HCl","SR33589","Cl.CCCCN(CCCC)CCCOC1=CC=C(C=C1)C(=O)C2=C(CCCC)OC3=CC=C(N[S](C)(=O)=O)C=C23",7.397,5,1,18]
["S2118","Ibutilide Fumarate","c3","L8000-06","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Ibutilide Fumarate (U-70226E,Corvert Fumarate) is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells.",885.23,"122647-32-9",{"v":89,"d":"89.00"},100.54,{"v":89,"d":"89.00"},100.54,"http://selleckchem.com/products/ibutilide-fumarate.html","(C20H36N2O3S)2.C4H4O4","Fumarate","U-70226E,Corvert Fumarate","CCCCCCCN(CC)CCCC(O)C1=CC=C(N[S](C)(=O)=O)C=C1.CCCCCCCN(CC)CCCC(O)C2=CC=C(N[S](C)(=O)=O)C=C2.OC(=O)\\C=C\\C(O)=O",1.954,6,4,30]
["S2119","Probucol","d3","L8000-06","in 10mM DMSO","LDL","Metabolism","Probucol (DH-581) is an anti-hyperlipidemic drug by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.",516.84,"23288-49-5",{"v":103,"d":"103.00"},199.29,"<1","N/A","http://selleckchem.com/products/probucol.html","C31H48O2S2","free base","DH-581","CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SC(C)(C)SC2=CC(=C(O)C(=C2)C(C)(C)C)C(C)(C)C",9.779,0,2,8]
["S2125","Mestranol","e3","L8000-06","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Mestranol is the 3-methyl ether of ethinyl estradiol, which is a potent estrogen receptor agonist and used as oral contraceptives.",310.43,"72-33-3",{"v":15,"d":"15.00"},48.32,"<1","N/A","http://selleckchem.com/products/Mestranol.html","C21H26O2","free base","N/A","COC1=CC2=C(C=C1)C3CCC4(C)C(CCC4(O)C#C)C3CC2",5.112,1,0,1]
["S2126","Naftopidil","f3","L8000-06","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Naftopidil (KT-611) is a selective α1-adrenergic receptor antagonist with Ki of 3.7 nM, 20 nM, and 1.2 nM for α1a, α1b, and α1d, respectively, used for the treatment of benign prostatic hyperplasia.",392.49,"57149-07-2",{"v":79,"d":"79.00"},201.28,"<1","N/A","http://selleckchem.com/products/Naftopidil(Flivas).html","C24H28N2O3","Free Base","KT-611","COC1=CC=CC=C1N2CCN(CC2)CC(O)COC3=C4C=CC=CC4=CC=C3",3.962,2,1,7]
["S2127","S-(+)-Rolipram","g3","L8000-06","in 10mM DMSO","PDE","Metabolism","S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.",275.34,"85416-73-5",{"v":55,"d":"55.00"},199.75,"<1","N/A","http://selleckchem.com/products/sRolipram.html","C16H21NO3","free base","N/A","COC1=C(OC2CCCC2)C=C(C=C1)C3CNC(=O)C3",2.349,3,1,4]
["S2128","Bazedoxifene (WAY-140424) HCl","h3","L8000-06","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Bazedoxifene HCl (WAY-140424, TSE-424) is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of  23 nM and 89 nM, respectively.",507.06,"198480-56-7",{"v":101,"d":"101.00"},199.19,"<1","N/A","http://selleckchem.com/products/bazedoxifene-hcl.html","C30H34N2O3.HCl","Hydrochloride","TSE-424","Cl.CC1=C([N](CC2=CC=C(OCCN3CCCCCC3)C=C2)C4=CC=C(O)C=C14)C5=CC=C(O)C=C5",7.602,1,2,7]
["S2130","Atropine sulfate monohydrate","a4","L8000-06","in 10mM DMSO","AChR,ADC Cytotoxin","Neuronal Signaling","Atropine sulfate monohydrate is a competitive antagonist for the muscarinic acetylcholine receptor, used to decrease the production of saliva and secretions of the airway prior to surgery.",694.83,"5908-99-6",{"v":139,"d":"139.00"},200.05,{"v":139,"d":"139.00"},200.05,"http://selleckchem.com/products/Atropine-sulfate-monohydrate.html","2(C17H23NO3).H2O.H2SO4","Sulfate monohydrate","N/A","O.CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN4C5CCC4CC(C5)OC(=O)C(CO)C6=CC=CC=C6.O[S](O)(=O)=O",2.628,4,2,10]
["S2131","Roflumilast (B9302-107)","b4","L8000-06","in 10mM DMSO","PDE","Metabolism","Roflumilast (APTA 2217, B9302-107, BY 217, BYK 20869) is a selective inhibitor of PDE4 with IC50 of 0.2-4.3 nM in a cell-free assay.",403.21,"162401-32-3",{"v":81,"d":"81.00"},200.89,"<1","N/A","http://selleckchem.com/products/Roflumilast(Daxas).html","C17H14Cl2F2N2O3","free base","APTA 2217, B9302-107, BY 217, BYK 20869","FC(F)OC1=CC=C(C=C1OCC2CC2)C(=O)NC3=C(Cl)C=NC=C3Cl",4.402,4,1,7]
["S2151","Sonidegib (NVP-LDE225)","c4","L8000-06","in 10mM DMSO","Hedgehog/Smoothened","Stem Cells & Wnt","Sonidegib (Erismodegib, NVP-LDE225) is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human) in cell-free assays, respectively. Phase 3.",{"v":485.5,"d":"485.50"},"956697-53-3",{"v":97,"d":"97.00"},199.79,"<1","N/A","http://selleckchem.com/products/LDE225(NVP-LDE225).html","C26H26F3N3O3","free base","Erismodegib","CC1CN(CC(C)O1)C2=CC=C(NC(=O)C3=C(C)C(=CC=C3)C4=CC=C(OC(F)(F)F)C=C4)C=N2",6.732,4,1,6]
["S2154","Dabigatran (BIBR-1048) etexilate","d4","L8000-06","in 10mM DMSO","Thrombin","Proteases","Dabigatran Etexilate (BIBR-1048) is the prodrug of dabigatran, a potent, nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule.",627.73,"211915-06-9",{"v":126,"d":"126.00"},200.72,"<1","N/A","http://selleckchem.com/products/BIBR-1048(Dabigatran-etexilate).html","C34H41N7O5","free base","BIBR-1048","CCCCCCOC(=O)N=C(N)C1=CC=C(NCC2=NC3=C(C=CC(=C3)C(=O)N(CCC(=O)OCC)C4=CC=CC=N4)[N]2C)C=C1",5.751,8,2,17]
["S2167","Bazedoxifene (TSE-424) acetate","e4","L8000-06","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Bazedoxifene Acetate (WAY-140424,TSE-424 acetate) is a third generation selective estrogen receptor modulator (SERM).",530.65,"198481-33-3",{"v":100,"d":"100.00"},188.45,"<1","N/A","http://selleckchem.com/products/Bazedoxifene-acetate.html","C30H34N2O3.C2H4O2","Acetate","WAY-140424,TSE-424 acetate","CC(O)=O.CC1=C([N](CC2=CC=C(OCCN3CCCCCC3)C=C2)C4=CC=C(O)C=C14)C5=CC=C(O)C=C5",3.981,2,2,7]
["S2169","Rosuvastatin (ZD4522) calcium","f4","L8000-06","in 10mM DMSO","COVID-19,HMG-CoA Reductase","Metabolism","Rosuvastatin Calcium (ZD4522 calcium) is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM in a cell-free assay.",500.57,"147098-20-2",{"v":100,"d":"100.00"},199.77,"<1","N/A","http://selleckchem.com/products/Rosuvastatin-calcium(Crestor).html","C22H28FN3O6S.1/2Ca","Calcium salt","ZD4522 calcium","[Ca++].CC(C)C1=C(\\C=C\\C(O)CC(O)CC([O-])=O)C(=NC(=N1)N(C)[S](C)(=O)=O)C2=CC=C(F)C=C2.CC(C)C3=C(\\C=C\\C(O)CC(O)CC([O-])=O)C(=NC(=N3)N(C)[S](C)(=O)=O)C4=CC=C(F)C=C4",1.906,8,4,20]
["S2173","Telotristat Etiprate (LX 1606 Hippurate)","g4","L8000-06","in 10mM DMSO","Hydroxylase","Metabolism","Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. Phase 3.",754.15,"1137608-69-5",{"v":100,"d":"100.00"},{"v":132.6,"d":"132.60"},"<1","N/A","http://selleckchem.com/products/telotristat-etiprate-lx-1606-hippurate.html","C27H26ClF3N6O3.C9H9NO3","Hippuric acid","N/A","CCOC(=O)C(N)CC1=CC=C(C=C1)C2=CC(=NC(=N2)N)OC(C3=CC=C(Cl)C=C3[N]4C=CC(=N4)C)C(F)(F)F.OC(=O)CNC(=O)C5=CC=CC=C5",3.747,8,3,14]
["S2177","Dichlorphenamide","h4","L8000-06","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Dichlorphenamide (Diclofenamide) is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class.",305.16,"120-97-8",{"v":61,"d":"61.00"},199.89,"N/A","N/A","http://www.selleckchem.com/products/Dichlorphenamide(Diclofenamide).html","C6H6Cl2N2O4S2","Free Base","Diclofenamide","N[S](=O)(=O)C1=CC(=C(Cl)C(=C1)[S](N)(=O)=O)Cl","N/A","N/A","N/A","N/A"]
["S2180","Ixazomib (MLN2238)","a5","L8000-06","in 10mM DMSO","Autophagy,Proteasome","Proteases","Ixazomib (MLN2238) inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM in cell-free assays, respectively, also inhibits the caspase-like (β1) and trypsin-like (β2) proteolytic sites, with IC50 of 31 and 3500 nM. Ixazomib (MLN2238) induces autophagy. Phase 3.",361.03,"1072833-77-2",{"v":72,"d":"72.00"},199.43,"<1","N/A","http://selleckchem.com/products/MLN-2238.html","C14H19BCl2N2O4","Free Base","N/A","CC(C)CC(NC(=O)CNC(=O)C1=C(Cl)C=CC(=C1)Cl)B(O)O",3.344,2,2,7]
["S2181","Ixazomib Citrate (MLN9708) Analogue","b5","L8000-06","in 10mM DMSO","Autophagy,Proteasome","Proteases","Ixazomib Citrate (MLN9708) Analogue is the analogue of Ixazomib Citrate (MLN9708) from WO2016165677A1. Ixazomib Citrate (MLN9708) immediately hydrolyzed to Ixazomib (MLN2238), the biologically active form, on exposure to aqueous solutions or plasma. Ixazomib (MLN2238) inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50/Ki of 3.4 nM/0.93 nM in cell-free assays, less potent to β1 and little activity to β2. Ixazomib (MLN2238) induces autophagy. Phase 3.",517.12,"1201902-80-8",{"v":100,"d":"100.00"},193.38,"<1","N/A","http://selleckchem.com/products/MLN9708.html","C20H23BCl2N2O9","free base","N/A","CC(C)CC(NC(=O)CNC(=O)C1=C(Cl)C=CC(=C1)Cl)B2OC(=O)CC(CC(O)=O)(O2)C(O)=O",3.497,7,2,10]
["S2199","Aliskiren Hemifumarate","c5","L8000-06","in 10mM DMSO","RAAS","Endocrinology & Hormones","Aliskiren hemifumarate(CGP 60536 hemifumarate, CGP60536B hemifumarate, SPP 100 hemifumarate) is a direct renin inhibitor with IC50 of 1.5 nM.",609.83,"173334-58-2",{"v":100,"d":"100.00"},163.98,{"v":100,"d":"100.00"},163.98,"http://selleckchem.com/products/Aliskiren-hemifumarate.html","C30H53N3O6.1/2C4H4O4","fumarate salt","CGP 60536 hemifumarate, CGP60536B hemifumarate, SPP 100 hemifumarate","COCCCOC1=C(OC)C=CC(=C1)CC(CC(N)C(O)CC(C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C.COCCCOC2=C(OC)C=CC(=C2)CC(CC(N)C(O)CC(C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C.OC(=O)\\C=C\\C(O)=O",1.735,12,8,40]
["S2217","Irinotecan (CPT-11) HCl Trihydrate","e5","L8000-06","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Irinotecan (CPT-11) prevents DNA from unwinding by inhibition of topoisomerase 1.",677.18,"136572-09-3",{"v":100,"d":"100.00"},147.67,{"v":1,"d":"1.00"},1.48,"http://selleckchem.com/products/Irinotecan-Hcl-Trihydrate-Campto.html","C33H38N4O6.HCl.3H2O","HCl & trihydrat","CPT-11 HCl Trihydrate","O.O.O.Cl.CCC1=C2CN3C(=O)C4=C(C=C3C2=NC5=CC=C(OC(=O)N6CCC(CC6)N7CCCCC7)C=C15)C(O)(CC)C(=O)OC4",3.446,6,0,5]
["S2226","Idelalisib","f5","L8000-06","in 10mM DMSO","Autophagy,PI3K","PI3K/Akt/mTOR","Idelalisib (CAL-101, GS-1101) is a selective p110δ inhibitor with IC50 of 2.5 nM in cell-free assays; shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR. Idelalisib also stimulates autophagy.",415.42,"870281-82-6",{"v":83,"d":"83.00"},{"v":199.8,"d":"199.80"},"<1","N/A","http://selleckchem.com/products/CAL-101.html","C22H18FN7O","free base","CAL-101, GS-1101","CCC(NC1=C2N=C[NH]C2=NC=N1)C3=NC4=CC=CC(=C4C(=O)N3C5=CC=CC=C5)F",3.624,5,2,5]
["S2229","Eltrombopag (SB497115) Olamine","g5","L8000-06","in 10mM DMSO","TpoR","Immunology & Inflammation","Eltrombopag Olamine (SB-497115-GR, Revolade, Promacta,Promacta Olamine) is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR).",564.63,"496775-62-3",{"v":89,"d":"89.00"},157.63,"<1","N/A","http://selleckchem.com/products/Eltrombopag-SB-497115-GR.html","C29H36N6O6","diolamine","SB-497115-GR, Revolade, Promacta,Promacta Olamine","CC1=CC=C(C=C1C)N2N=C(C)C(=N/NC3=CC=CC(=C3O)C4=CC(=CC=C4)C(O)=O)/C2=O.NCCO.NCCO",-0.151,4,6,7]
["S2233","Esomeprazole sodium","h5","L8000-06","in 10mM DMSO","ATPase","Transmembrane Transporters","Esomeprazole Sodium((S)-Omeprazole sodium, (-)-Omeprazole sodium) is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.",{"v":367.4,"d":"367.40"},"161796-78-7",{"v":73,"d":"73.00"},198.69,{"v":73,"d":"73.00"},198.69,"http://selleckchem.com/products/esomeprazole-sodium.html","C17H18N3O3S.Na","Sodium salt","(S)-Omeprazole sodium, (-)-Omeprazole sodium","COC1=CC=C2[N]([Na])C(=NC2=C1)[S](=O)CC3=NC=C(C)C(=C3C)OC",3.008,5,0,5]
["S2246","Abiraterone Acetate (CB7630)","a6","L8000-06","in 10mM DMSO","Androgen Receptor,P450 (e.g. CYP17)","Metabolism","Abiraterone Acetate (CB7630, CB-7630) is an acetate salt form of Abiraterone which is a steroidal cytochrome CYP17 inhibitor with IC50 of 72 nM in a cell-free assay. Abiraterone acetate is an oral androgen biosynthesis inhibitor.",391.55,"154229-18-2",{"v":20,"d":"20.00"},51.08,"<1","N/A","http://www.selleck.cn/products/Abiraterone-Acetate-CB7630.html","C26H33NO2","Acetate","CB7630, CB-7630","CC(=O)OC1CCC2(C)C3CCC4(C)C(CC=C4C5=CC=CN=C5)C3CC=C2C1",4.602,3,0,3]
["S2250","(-)-Epigallocatechin Gallate","b6","L8000-06","in 10mM DMSO","DNA Methyltransferase,EGFR,Fatty Acid Synthase,HER2,Telomerase","DNA Damage/DNA Repair","(-)-Epigallocatechin Gallate(EGCG) is the main catechin extraction of green tea that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 receptors. ECGG inhibits fatty acid synthase and glutamate dehydrogenase activity.",458.37,"989-51-5",{"v":72,"d":"72.00"},157.08,{"v":23,"d":"23.00"},50.18,"http://selleckchem.com/products/(-)-Epigallocatechin-gallate.html","C22H18O11","free base","EGCG","OC1=CC2=C(CC(OC(=O)C3=CC(=C(O)C(=C3)O)O)C(O2)C4=CC(=C(O)C(=C4)O)O)C(=C1)O",3.097,3,8,4]
["S2256","4-Methylumbelliferone (4-MU)","c6","L8000-06","in 10mM DMSO","Others","Others","4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM.",176.17,"90-33-5",{"v":35,"d":"35.00"},198.67,"<1","N/A","http://selleckchem.com/products/4-Methylumbelliferone(4-MU).html","C10H8O3","free base","N/A","CC1=CC(=O)OC2=C1C=CC(=C2)O",2.104,2,1,0]
["S2258","Esculin","d6","L8000-06","in 10mM DMSO","Others","Others","Esculin (Aesculin) is a glucoside found in horse chestnuts.",340.28,"531-75-9",{"v":68,"d":"68.00"},199.84,{"v":2,"d":"2.00"},5.88,"http://selleckchem.com/products/Aesculin(Esculin).html","C15H16O9","free base","Aesculin","OCC1OC(OC2=C(O)C=C3OC(=O)C=CC3=C2)C(O)C(O)C1O",-0.514,4,5,3]
["S2260","Amygdalin","e6","L8000-06","in 10mM DMSO","Others","Others","Amygdalin is a glycoside initially isolated from the seeds of the tree Prunus dulcis, also known as bitter almonds.",457.43,"29883-15-6",{"v":91,"d":"91.00"},198.94,"<1","N/A","http://selleckchem.com/products/Amygdalin.html","C20H27NO11","free base","N/A","OCC1OC(OCC2OC(OC(C#N)C3=CC=CC=C3)C(O)C(O)C2O)C(O)C(O)C1O",-2.403,4,7,7]
["S2261","Andrographolide","f6","L8000-06","in 10mM DMSO","NF-κB","NF-κB","Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata.",350.45,"5508-58-7",{"v":70,"d":"70.00"},199.74,"<1","N/A","http://selleckchem.com/products/Andrographolide.html","C20H30O5","free base","N/A","CC1(CO)C(O)CCC2(C)C(C\\C=C\\3C(O)COC3=O)C(=C)CCC12",2.056,2,3,3]
["S2262","Apigenin (LY 080400)","g6","L8000-06","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Apigenin (NSC 83244, LY 080400) is a potent P450 inhibitor for CYP2C9 with Ki of 2 μM.",270.24,"520-36-5",{"v":54,"d":"54.00"},199.82,"<1","N/A","http://selleckchem.com/products/Apigenin.html","C15H10O5","free base","NSC 83244","OC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(O)C=C3O",{"v":2.41,"d":"2.410"},2,3,1]
["S2263","Arbutin","h6","L8000-06","in 10mM DMSO","Tyrosinase","Proteases","Arbutin (Uva, p-Arbutin, β-Arbutin) is a tyrosinase inhibitor with IC50 of 0.9 mM and 0.7 mM for Monophenolase and Diphenolase, respectively.",272.25,"497-76-7",{"v":55,"d":"55.00"},202.02,{"v":55,"d":"55.00"},202.02,"http://selleckchem.com/products/Arbutin(Uva,-p-Arbutin).html","C12H16O7","free base","Uva,p-Arbutin, β-Arbutin","OCC1OC(OC2=CC=C(O)C=C2)C(O)C(O)C1O",-0.584,2,5,3]
["S2264","Artemether","a7","L8000-06","in 10mM DMSO","ADC Cytotoxin,Anti-infection","Microbiology","Artemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria.",298.37,"71963-77-4",{"v":60,"d":"60.00"},201.09,"<1","N/A","http://selleckchem.com/products/Artemether(SM-224).html","C16H26O5","free base","SM-224, CGP 56696","COC1OC2OC3(C)CCC4C(C)CCC(C1C)C24OO3",2.029,5,0,1]
["S2265","Artesunate (WR-256283)","b7","L8000-06","in 10mM DMSO","ADC Cytotoxin,STAT","JAK/STAT","Artesunate (WR-256283) is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69. It is a potential inhibitor of STAT-3 and exhibits selective cytotoxicity of cancer cells over normal cells in vitro; A potent inhibitor of EXP1.",384.42,"88495-63-0",{"v":77,"d":"77.00"},{"v":200.3,"d":"200.30"},"<1","N/A","http://selleckchem.com/products/Artesunate.html","C19H28O8","free base","WR-256283","CC1CCC2C(C)C(OC3OC4(C)CCC1C23OO4)OC(=O)CCC(O)=O",1.845,7,0,5]
["S2266","Asiatic Acid","c7","L8000-06","in 10mM DMSO","p38 MAPK","MAPK","Asiatic acid (Dammarolic acid, Asiantic acid) is the aglycone of asiaticoside isolated from the plant Centella asiatica, commonly used in wound healing.",{"v":488.7,"d":"488.70"},"464-92-6",{"v":97,"d":"97.00"},198.49,"<1","N/A","http://selleckchem.com/products/Asiatic-acid.html","C30H48O5","free base","Dammarolic acid, Asiantic acid","CC1CCC2(CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(CO)C5CCC34C)C2C1C)C(O)=O",4.435,1,3,2]
["S2268","Baicalein","d7","L8000-06","in 10mM DMSO","P450 (e.g. CYP17),PREP","Metabolism","Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor.",270.24,"491-67-8",{"v":54,"d":"54.00"},199.82,"<1","N/A","http://selleckchem.com/products/Baicalein.html","C15H10O5","free base","N/A","OC1=C(O)C(=C2C(=O)C=C(OC2=C1)C3=CC=CC=C3)O",{"v":2.41,"d":"2.410"},2,3,1]
["S2269","Baicalin (NSC-661431)","e7","L8000-06","in 10mM DMSO","GABA Receptor,PREP","Neuronal Signaling","Baicalin (NSC-661431) is a known prolyl endopeptidase inhibitor and affects the GABA receptors.",446.36,"21967-41-9",{"v":89,"d":"89.00"},199.39,"<1","N/A","http://selleckchem.com/products/Baicalin.html","C21H18O11","free base","N/A","OC1C(O)C(OC(C1O)C(O)=O)OC2=C(O)C(=C3C(=O)C=C(OC3=C2)C4=CC=CC=C4)O",0.608,5,5,4]
["S2270","Bergenin","f7","L8000-06","in 10mM DMSO","Others","Others","Bergenin (Cuscutin) is trihydroxybenzoic acid glycoside and the C-glycoside of 4-O-methyl gallic acid.",328.27,"477-90-7",{"v":66,"d":"66.00"},201.05,"<1","N/A","http://selleckchem.com/products/Bergenin-(Cuscutin).html","C14H16O9","free base","Cuscutin","COC1=C(O)C2=C(C=C1O)C(=O)OC3C(O)C(O)C(CO)OC23",-0.849,4,5,2]
["S2271","Berberine chloride (NSC 646666)","g7","L8000-06","in 10mM DMSO","Anti-infection,Apoptosis related,Autophagy,Bcl-2,Caspase,IAP,JNK,p38 MAPK,P450 (e.g. CYP17),PARP,ROS,Topoisomerase","Microbiology","Berberine chloride (NSC 646666, Natural Yellow 18) is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. Berberine chloride decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. Berberine chloride induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. Berberine chloride is a dual topoisomerase I and II inhibitor. Berberine chloride is also a potential autophagy modulator.",371.81,"633-65-8",{"v":40,"d":"40.00"},107.58,"<1","N/A","http://selleckchem.com/products/Berberine-Hydrochloride.html","C20H18NO4.Cl","chloride","Natural Yellow 18 chloride","[Cl-].COC1=CC=C2C=C3C4=C(CC[N+]3=CC2=C1OC)C=C5OCOC5=C4",1.289,4,0,2]
["S2277","Caffeic Acid","h7","L8000-06","in 10mM DMSO","Lipoxygenase,TRP Channel","Transmembrane Transporters","Caffeic acid is a hydroxycinnamic acid, a naturally occurring organic compound. Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO).",180.16,"331-39-5",{"v":36,"d":"36.00"},199.82,"<1","N/A","http://selleckchem.com/products/Caffeic-acid.html","C9H8O4","free base","N/A","OC(=O)/C=C/C1=CC=C(O)C(=C1)O",1.443,1,2,2]
["S2280","Chlorogenic Acid","a8","L8000-06","in 10mM DMSO","Others","Others","Chlorogenic acid (NSC 407296, Heriguard) is a hydroxycinnamic acid and a member of a family of naturally occurring organic compounds.",354.31,"327-97-9",{"v":71,"d":"71.00"},200.39,{"v":18,"d":"18.00"},{"v":50.8,"d":"50.80"},"http://selleckchem.com/products/Chlorogenic-acid.html","C16H18O9","free base","NSC 407296, Heriguard","OC1CC(O)(CC(OC(=O)\\C=C\\C2=CC(=C(O)C=C2)O)C1O)C(O)=O",{"v":-0.34,"d":"-0.340"},3,4,5]
["S2283","Cinchonine(LA40221)","b8","L8000-06","in 10mM DMSO","5-alpha Reductase","Angiogenesis","Cinchonine (LA40221) is an alkaloid and a stereoisomer and pseudo-enantiomer of cinchonidine.",{"v":294.4,"d":"294.40"},"118-10-5",{"v":9,"d":"9.00"},30.57,"N/A","N/A","http://selleckchem.com/products/cinchonine.html","C19H22N2O","free base","N/A","OC(C1CC2CCN1CC2C=C)C3=CC=NC4=CC=CC=C34",{"v":2.75,"d":"2.750"},1,1,3]
["S2284","Colchicine (NSC 757)","c8","L8000-06","in 10mM DMSO","Microtubule Associated","Cell Cycle","Colchicine (NSC 757, Colchineos, Colchisol, Colcin) is a microtubule polymerization inhibitor with an IC50 of 3 nM.",399.44,"64-86-8",{"v":80,"d":"80.00"},200.28,{"v":80,"d":"80.00"},200.28,"http://selleckchem.com/products/colchicine.html","C22H25NO6","free base","Colchineos, Colchisol, Colcin,NSC 757","COC1=CC=C2C(=CC1=O)C(CCC3=C2C(=C(OC)C(=C3)OC)OC)NC(C)=O",2.044,6,1,5]
["S2286","Cyclosporin A (NSC 290193)","d8","L8000-06","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,Complement System,Immunology & Inflammation related,phosphatase","Immunology & Inflammation","Cyclosporin A (Cyclosporine A, Cyclosporine, Ciclosporin, CsA,NSC 290193) is an immunosuppressive agent, binds to the cyclophilin and then inhibits calcineurin with IC50 of 7 nM in a cell-free assay, widely used in organ transplantation to prevent rejection.",1202.61,"59865-13-3",{"v":100,"d":"100.00"},83.15,"<1","N/A","http://selleckchem.com/products/Cyclosporin-A(Cyclosporine-A).html","C62H111N11O12","free base","Cyclosporine A, Cyclosporine, Ciclosporin, CsA,NSC 290193","CCC1NC(=O)C(C(O)C(C)C\\C=C\\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C",4.333,11,5,15]
["S2287","Cytisine","e8","L8000-06","in 10mM DMSO","AChR","Neuronal Signaling","Cytisine (Baphitoxine, Sophorine) is a nicotinic acetylcholine receptor agonist.",190.24,"485-35-8",{"v":38,"d":"38.00"},199.75,{"v":38,"d":"38.00"},199.75,"http://selleckchem.com/products/Cytisine(Baphitoxine,-Sophorine).html","C11H14N2O","free base","Baphitoxine,Sophorine","O=C1C=CC=C2C3CNCC(C3)CN12",-0.338,1,1,0]
["S2289","Daidzin","f8","L8000-06","in 10mM DMSO","Dehydrogenase","Metabolism","Daidzin (Daidzoside, Daidzein 7-O-glucoside, Daidzein 7-glucoside), a natural organic compound in the class of phytochemicals known as isoflavones, is a potent and selective inhibitor of human mitochondrial aldehyde dehydrogenase and inhibits ALDH-I selectively (Ki=20 nM); at least 500 times less effective against ALDH-Ⅱ, the cytosolic isozyme (Ki=10 μM).",416.38,"552-66-9",{"v":83,"d":"83.00"},199.34,"<1","N/A","http://selleckchem.com/products/Daidzin.html","C21H20O9","Free Base","Daidzoside, Daidzein 7-O-glucoside, Daidzein 7-glucoside","OCC1OC(OC2=CC3=C(C=C2)C(=O)C(=CO3)C4=CC=C(O)C=C4)C(O)C(O)C1O",0.452,4,5,4]
["S2290","Dihydroartemisinin (DHA)","g8","L8000-06","in 10mM DMSO","Apoptosis related,Autophagy,NF-κB","NF-κB","Dihydroartemisinin (DHA, Dihydroqinghaosu, β-Dihydroartemisinin, Artenimol) is a semi-synthetic derivative of artemisinin and isolated from the traditional Chinese herb Artemisia annua. Dihydroartemisinin induces autophagy and apoptosis by suppressing NF-κB activation.",284.35,"71939-50-9",{"v":56,"d":"56.00"},196.94,"<1","N/A","http://selleckchem.com/products/Dihydroartemisinin(DHA).html","C15H24O5","free base","Dihydroqinghaosu, β-Dihydroartemisinin, Artenimol","CC1CCC2C(C)C(O)OC3OC4(C)CCC1C23OO4",1.621,4,0,0]
["S2295","Emodin","h8","L8000-06","in 10mM DMSO","Dehydrogenase","Metabolism","Emodin is a purgative resin, 6-methyl-1,3,8-trihydroxyanthraquinone, from rhubarb, the buckthorn and Japanese Knotweed (Fallopia japonica).",270.24,"518-82-1",{"v":54,"d":"54.00"},199.82,"<1","N/A","http://selleckchem.com/products/Emodin.html","C15H10O5","free base","N/A","CC1=CC2=C(C(=C1)O)C(=O)C3=C(C=C(O)C=C3O)C2=O",2.568,2,3,0]
["S2296","Enoxolone","a9","L8000-06","in 10mM DMSO","Dehydrogenase","Metabolism","Enoxolone (Glycyrrhetin) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.",470.68,"471-53-4",{"v":94,"d":"94.00"},199.71,"<1","N/A","http://selleckchem.com/products/Enoxolone(Glycyrrhetin).html","C30H46O4","free base","Glycyrrhetin","CC1(C)C(O)CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O",5.656,2,1,1]
["S2299","Formononetin","b9","L8000-06","in 10mM DMSO","Others","Endocrinology & Hormones","Formononetin (Formononetol, Biochanin B) is a phytoestrogen from the root of Astragalus membranaceus and an O-methylated isoflavone.",268.26,"485-72-3",{"v":54,"d":"54.00"},{"v":201.3,"d":"201.30"},"<1","N/A","http://selleckchem.com/products/Formononetin(Formononetol).html","C16H12O4","free base","Formononetol, Biochanin B","COC1=CC=C(C=C1)C2=COC3=C(C=CC(=C3)O)C2=O",2.608,3,1,2]
["S2300","Ferulic Acid","c9","L8000-06","in 10mM DMSO","FGFR","Angiogenesis","Ferulic Acid (Fumalic) is a hydroxycinnamic acid and a type of organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong. Ferulic acid is a novel fibroblast growth factor receptor (FGFR) inhibitor with IC50s of 3.78 μM and 12.5 μM for FGFR1 and FGFR2, respectively.",194.19,"1135-24-6",{"v":39,"d":"39.00"},200.83,"<1","N/A","http://selleckchem.com/products/Fumalic-acid(Ferulic-acid).html","C10H10O4","free base","Fumalic Acid","COC1=CC(=CC=C1O)\\C=C\\C(O)=O",1.669,2,1,3]
["S2302","Glycyrrhizin (NSC 167409)","d9","L8000-06","in 10mM DMSO","Dehydrogenase,High-mobility Group,MAO","Metabolism","Glycyrrhizin (NSC 167409, Glycyrrhizic Acid) is a direct HMGB1(high mobility group box 1) inhibitor that inhibits HMGB1-dependent inflammatory molecule expression and oxidative stress; modulates P38 and P-JNK but not p-ERK signalling; Also inhibits 11 beta-hydroxysteroid dehydrogenase and monoamine oxidase (MAO).",822.93,"1405-86-3",{"v":100,"d":"100.00"},121.52,"<1","N/A","http://selleckchem.com/products/Glycyrrhizic-acid.html","C42H62O16","free base","N/A","CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O)OC6OC(C(O)C(O)C6OC7OC(C(O)C(O)C7O)C(O)=O)C(O)=O",2.417,8,5,7]
["S2303","Gossypol Acetate","e9","L8000-06","in 10mM DMSO","Dehydrogenase","Metabolism","Gossypol Acetate (Gossypol Acetic acid, Pogosin, AT101) is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes.",578.61,"12542-36-8",{"v":100,"d":"100.00"},172.83,"<1","N/A","https://www.selleckchem.com/products/gossypol-acetate.html","C32H34O10","Acetate","Gossypol Acetic acid, Pogosin, AT101","CC(C)C1=C2C=C(C)C(=C(O)C2=C(C=O)C(=C1O)O)C3=C(O)C4=C(C=C3C)C(=C(O)C(=C4C=O)O)C(C)C.CC(O)=O",6.388,3,6,5]
["S2304","Gramine","f9","L8000-06","in 10mM DMSO","ADC Cytotoxin,AdipoR,Adrenergic Receptor","Metabolism","Gramine (Donaxine) is a natural indole alkaloid isolated from giant reed, acts as an active adiponectin receptor (AdipoR) agonist, with IC50 of 3.2 µM and 4.2 µM for AdipoR2 and AdipoR1, respectively. Gramine is also a human and mouse β2-Adrenergic receptor (β2-AR) agonist.",174.24,"87-52-5",{"v":35,"d":"35.00"},200.87,"<1","N/A","http://selleckchem.com/products/Gramine.html","C11H14N2","free base","N/A","CN(C)CC1=C[NH]C2=C1C=CC=C2",2.197,0,1,2]
["S2308","Hesperetin","g9","L8000-06","in 10mM DMSO","Histamine Receptor,TGF-beta/Smad","TGF-beta/Smad","Hesperetin is a bioflavonoid and, to be more specific, a flavanone.",302.27,"520-33-2",{"v":60,"d":"60.00"},{"v":198.5,"d":"198.50"},"<1","N/A","http://selleckchem.com/products/Hesperetin.html","C16H14O6","free base","N/A","COC1=CC=C(C=C1O)C2CC(=O)C3=C(O)C=C(O)C=C3O2",2.357,3,3,2]
["S2309","Hesperidin","h9","L8000-06","in 10mM DMSO","Others","Others","Hesperidin (Cirantin) is a flavanone glycoside found abundantly in citrus fruits.",610.56,"520-26-3",{"v":100,"d":"100.00"},163.78,"<1","N/A","http://selleckchem.com/products/Hesperidin.html","C28H34O15","free base","Cirantin","COC1=CC=C(C=C1O)C2CC(=O)C3=C(O)C=C(OC4OC(COC5OC(C)C(O)C(O)C5O)C(O)C(O)C4O)C=C3O2",-0.431,7,8,7]
["S2310","Honokiol (NSC 293100)","a10","L8000-06","in 10mM DMSO","Akt,Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,Autophagy,HCV,MEK","PI3K/Akt/mTOR","Honokiol (NSC 293100) is the active principle of magnolia extract that inhibits Akt-phosphorylation and promotes ERK1/2 phosphorylation. Honokiol causes G0/G1 phase arrest, induces apoptosis, and autophagy via the ROS/ERK1/2 signaling pathway. Honokiol inhibits hepatitis C virus (HCV) infection. Phase 3.",266.33,"35354-74-6",{"v":53,"d":"53.00"},{"v":199,"d":"199.00"},"<1","N/A","http://selleckchem.com/products/Honokiol.html","C18H18O2","free base","N/A","OC1=C(CC=C)C=C(C=C1)C2=CC(=CC=C2O)CC=C",{"v":4.88,"d":"4.880"},0,2,5]
["S2311","Hyodeoxycholic acid (HDCA)","b10","L8000-06","in 10mM DMSO","GPCR19","GPCR & G Protein","Hyodeoxycholic (HDCA, NSC 60672) acid is a secondary bile acid, one of the metabolic byproducts of intestinal bacteria.",392.57,"83-49-8",{"v":78,"d":"78.00"},198.69,"<1","N/A","http://selleckchem.com/products/Hyodeoxycholic-acid(HDCA).html","C24H40O4","free base","NSC 60672","CC(CCC(O)=O)C1CCC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C",4.014,1,2,4]
["S2314","Kaempferol (NSC 407289)","c10","L8000-06","in 10mM DMSO","Estrogen/progestogen Receptor,Fatty Acid Synthase","Endocrinology & Hormones","Kaempferol (NSC 407289, Robigenin), a natural flavonol, functions as an ERRα and ERRγ inverse agonist. It inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase.",286.23,"520-18-3",{"v":57,"d":"57.00"},199.14,"<1","N/A","http://selleckchem.com/products/Kaempferol.html","C15H10O6","free base","Robigenin","OC1=CC=C(C=C1)C2=C(O)C(=O)C3=C(O)C=C(O)C=C3O2",1.872,2,4,1]
["S2318","Lappaconitine","d10","L8000-06","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Lappaconitine (LC) is a natural diterpenoid alkaloid (DTA), acting as a human heart sodium channel blocker and possessing a wide range of biological activities, including anti-arrhythmic, anti-inflammatory, antioxidative, anticancer, epileptiform etc.",{"v":584.7,"d":"584.70"},"32854-75-4",{"v":16,"d":"16.00"},27.36,"N/A","N/A","http://selleckchem.com/products/lappaconitine.html","C32H44N2O8","free base","N/A","CCN1CC2(CCC(OC)C34C2CC(C13)C5(O)CC(OC)C6CC4C5(O)C6OC)OC(=O)C7=CC=CC=C7NC(C)=O",0.029,6,1,8]
["S2320","Luteolin","e10","L8000-06","in 10mM DMSO","ADC Cytotoxin,PDE","Metabolism","Luteolin (Luteoline, Luteolol, Digitoflavone) is a flavonoid found in Terminalia chebula, which is a non-selective phisphodiesterase PDE inhibitor for PDE1-5 with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM, respectively.",286.24,"491-70-3",{"v":57,"d":"57.00"},199.13,"<1","N/A","https://www.selleckchem.com/products/luteolin.html","C15H10O6","free base","Luteoline, Luteolol, Digitoflavone","OC1=CC(=C2C(=O)C=C(OC2=C1)C3=CC=C(O)C(=C3)O)O",2.168,2,4,1]
["S2321","Magnolol","f10","L8000-06","in 10mM DMSO","Fungal,NF-κB","NF-κB","Magnolol (NSC 293099) is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. It can block TNF-α-induced NF-KB activation.",266.33,"528-43-8",{"v":53,"d":"53.00"},{"v":199,"d":"199.00"},"<1","N/A","http://selleckchem.com/products/Magnolol(2,2-Bichavicol).html","C18H18O2","free base","NSC 293099","OC1=C(C=C(CC=C)C=C1)C2=CC(=CC=C2O)CC=C",{"v":4.88,"d":"4.880"},0,2,5]
["S2322","(+)-Matrine","g10","L8000-06","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","Matrine((+)-Matrine) is an alkaloid found in plants from the Sophora family, which has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist.",248.36,"519-02-8",{"v":49,"d":"49.00"},197.29,{"v":11,"d":"11.00"},44.29,"http://selleckchem.com/products/matrine.html","C15H24N2O","free base","N/A","O=C1CCCC2C3CCCN4CCCC(CN12)C34",1.417,1,0,0]
["S2325","Morin Hydrate","h10","L8000-06","in 10mM DMSO","Others","Others","Morin hydrate (Aurantica) is a flavonoid isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava).",320.25,"6202-27-3",{"v":64,"d":"64.00"},199.84,"<1","N/A","https://www.selleckchem.com/products/Morin-hydrate.html","C15H10O7.H2O","Hydrate","Aurantica","O.OC1=CC=C(C(=C1)O)C2=C(O)C(=O)C3=C(O)C=C(O)C=C3O2",1.423,2,5,1]
["S2328","Nalidixic acid","a11","L8000-06","in 10mM DMSO","Selection Antibiotics for Transfected Cell,Topoisomerase","DNA Damage/DNA Repair","Nalidixic acid (NSC-82174) is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.",232.24,"389-08-2",{"v":6,"d":"6.00"},25.84,"<1","N/A","http://selleckchem.com/products/Nalidixic-acid(NegGram).html","C12H12N2O3","free base","NSC-82174","CCN1C=C(C(O)=O)C(=O)C2=C1N=C(C)C=C2",1.176,3,0,2]
["S2329","Naringin","b11","L8000-06","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Naringin (Naringoside) is a flavanone glycoside, which exerts a variety of pharmacological effects such as antioxidant activity, blood lipid lowering, anticancer activity, and inhibition of cytochrome P450 enzymes.",580.53,"10236-47-2",{"v":100,"d":"100.00"},172.26,"<1","N/A","http://selleckchem.com/products/Naringin(Naringoside).html","C27H32O14","free base","Naringoside","CC1OC(OC2C(O)C(O)C(CO)OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC=C(O)C=C5)O)C(O)C(O)C1O",-0.415,6,8,6]
["S2331","Neohesperidin Dihydrochalcone (Nhdc)","c11","L8000-06","in 10mM DMSO","Others","Others","Neohesperidin dihydrochalcone(Nhdc, NCI-c60764), sometimes abbreviated to neohesperidin DC or simply NHDC, is an artificial sweetener derived from citrus.",612.58,"20702-77-6",{"v":100,"d":"100.00"},163.24,"<1","N/A","http://selleckchem.com/products/Neohesperidin-dihydrochalcone(Nhdc).html","C28H36O15","free base","NCI-c60764","COC1=C(O)C=C(CCC(=O)C2=C(O)C=C(OC3OC(CO)C(O)C(O)C3OC4OC(C)C(O)C(O)C4O)C=C2O)C=C1",-0.048,6,9,10]
["S2332","Neohesperidin","d11","L8000-06","in 10mM DMSO","ROS","Immunology & Inflammation","Neohesperidin (NSC 31048), a flavanone glycoside found in citrus fruits, is an antioxidant agent., Neohesperidin (NSC 31048) 是一种抗氧化剂，在1,1-diphenyl-2-picryldydrazyl（DPPH）自由基清除测定中，IC50为22.31 μg/ml。",610.56,"13241-33-3",{"v":122,"d":"122.00"},199.82,"<1","N/A","http://selleckchem.com/products/Neohesperidin.html","C28H34O15","free base","NSC 31048","COC1=CC(=CC(=C1)C2CC(=O)C3=C(O)C=C(OC4OC(CO)C(O)C(O)C4OC5OC(C)C(O)C(O)C5O)C=C3O2)O",-0.431,7,8,7]
["S2334","Oleanolic Acid","e11","L8000-06","in 10mM DMSO","Antiviral","Microbiology","Oleanolic Acid (Caryophyllin) is a non-toxic, hepatoprotective triterpenoid found in Phytolacca Americana, which exerts antitumor and antiviral properties.",{"v":456.7,"d":"456.70"},"508-02-1",{"v":21,"d":"21.00"},45.98,"<1","N/A","http://selleckchem.com/products/Oleanolic-Acid(Caryophyllin).html","C30H48O3","free base","Caryophyllin","CC1(C)CC(C2CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC34C)C2C1)C(O)=O",6.282,1,1,1]
["S2336","Orotic acid (6-Carboxyuracil)","f11","L8000-06","in 10mM DMSO","Others","Others","Orotic acid(6-Carboxyuracil) is a heterocyclic compound and an acid.",{"v":156.1,"d":"156.10"},"65-86-1",{"v":2,"d":"2.00"},12.81,"<1","N/A","http://selleckchem.com/products/Orotic-acid(6-Carboxyuracil).html","C5H4N2O4","free base","N/A","OC(=O)C1=CC(=O)NC(=O)N1",-1.152,3,2,1]
["S2337","Osthole","g11","L8000-06","in 10mM DMSO","Others","Others","Osthol is an O-methylated coumarin, which is found in the plants such as Cnidium monnieri, Angelica archangelica and Angelica pubescens.",244.29,"484-12-8",{"v":49,"d":"49.00"},200.58,"<1","N/A","http://selleckchem.com/products/Osthole(Osthol).html","C15H16O3","free base","Osthol","COC1=CC=C2C=CC(=O)OC2=C1CC=C(C)C",{"v":3.74,"d":"3.740"},3,0,3]
["S2338","Oxymatrine","h11","L8000-06","in 10mM DMSO","Immunology & Inflammation related","TGF-beta/Smad","Oxymatrine (Matrine N-oxide) is a quinolizidine alkaloid extracted from the root of Sophora flavescens with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. It is used for the treatment of viral hepatitis, cancer, viral myocarditis, gastrointestinal hemorrhage and skin diseases.",264.36,"16837-52-8",{"v":53,"d":"53.00"},200.48,{"v":53,"d":"53.00"},200.48,"http://selleckchem.com/products/Oxymatrine(Matrine-N-oxide).html","C15H24N2O2","free base","Matrine N-oxide","[O-][N+]12CCCC3CN4C(CCCC4=O)C(CCC1)C23",{"v":0.61,"d":"0.610"},1,0,0]
["S2341","(-)-Parthenolide","a2","L8000-07","in 10mM DMSO","HDAC,MDM2/MDMX,NF-κB,p53","NF-κB","(-)-Parthenolide, an inhibitor of the Nuclear Factor-κB Pathway, specifically depletes HDAC1 protein without affecting other class I/II HDACs; Also promotes the ubiquitination of MDM2 and activates p53 cellular functions.",248.32,"20554-84-1",{"v":49,"d":"49.00"},197.33,"<1","N/A","http://selleckchem.com/products/Parthenolide((-)-Parthenolide).html","C15H20O3","free base","N/A","CC/1=C\\CCC2(C)OC2C3OC(=O)C(=C)C3CC1",2.923,3,0,0]
["S2344","Piperine","b2","L8000-07","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Piperine (1-Piperoylpiperidine) is the alkaloid responsible for the pungency of black pepper and long pepper, which has also been used in some forms of traditional medicine and as an insecticide.",285.34,"94-62-2",{"v":57,"d":"57.00"},199.76,"<1","N/A","http://selleckchem.com/products/Piperine(1-Piperoylpiperidine).html","C17H19NO3","free base","1-Piperoylpiperidine","O=C(\\C=C\\C=C\\C1=CC2=C(OCO2)C=C1)N3CCCCC3",2.864,3,0,3]
["S2346","Puerarin","c2","L8000-07","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Puerarin (Kakonein), an isoflavones found in the root of Radix puerariae, is a 5-HT2C receptor and benzodiazepine site antagonist.",416.38,"3681-99-0",{"v":86,"d":"86.00"},206.54,"<1","N/A","http://selleckchem.com/products/Puerarin(Kakonein).html","C21H20O9","free base","Kakonein","OCC1OC(OC2=C(O)C=CC3=C2OC=C(C3=O)C4=CC=C(O)C=C4)C(O)C(O)C1O",{"v":0.21,"d":"0.210"},4,6,4]
["S2347","Quercetin Dihydrate","d2","L8000-07","in 10mM DMSO","PI3K,Sirtuin","PI3K/Akt/mTOR","Quercetin (Sophoretin), a polyphenolic flavonoid found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine, is utilized in many different cultures for their nervous system and anticancer effects. Quercetin (dihydrate), a natural flavonoid, is a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC50s of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively.",338.27,"6151-25-3",{"v":67,"d":"67.00"},198.07,"<1","N/A","http://selleckchem.com/products/Quercetin-dihydrate(Sophoretin).html","C15H10O7.2H2O","Dihydrate","Sophoretin","O.O.OC1=CC(=C2C(=O)C(=C(OC2=C1)C3=CC=C(O)C(=C3)O)O)O",1.216,2,5,1]
["S2348","Rotenone (Barbasco)","e2","L8000-07","in 10mM DMSO","Apoptosis related,Mitochondrial Metabolism,Mitophagy,NADPH-oxidase,ROS","Immunology & Inflammation","Rotenone (Barbasco, Dactinol, Paraderil, Rotenon, Rotocide) is a botanical insecticide that is an inhibitor of mitochondrial electron transport. Rotenone inhibits NADH/DB oxidoreductase and NADH oxidase with IC50 of 28.8 nM and 5.1 nM, respectively. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production.",394.42,"83-79-4",{"v":78,"d":"78.00"},197.76,"N/A","N/A","http://selleckchem.com/products/rotenone-barbasco.html","C23H22O6","free base","Barbasco, Dactinol, Paraderil, Rotenon, Rotocide","COC1=CC2=C(C=C1OC)C3C(CO2)OC4=C(C=CC5=C4CC(O5)C(C)=C)C3=O",{"v":3.93,"d":"3.930"},6,0,3]
["S2349","Rutaecarpine","f2","L8000-07","in 10mM DMSO","COX","Neuronal Signaling","Rutaecarpine (Rutecarpine) is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs; a new class of COX-2 inhibitor.",287.32,"84-26-4",{"v":24,"d":"24.00"},83.53,"<1","N/A","http://selleckchem.com/products/Rutaecarpine(Rutecarpine).html","C18H13N3O","free base","Rutecarpine","O=C1N2CCC3=C([NH]C4=C3C=CC=C4)C2=NC5=C1C=CC=C5",3.359,2,1,0]
["S2350","Rutin","g2","L8000-07","in 10mM DMSO","ADC Cytotoxin,Immunology & Inflammation related","Immunology & Inflammation","Rutin (Rutoside), a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human.",610.52,"153-18-4",{"v":100,"d":"100.00"},163.79,"<1","N/A","http://selleckchem.com/products/Rutin(Rutoside).html","C27H30O16","free base","Rutoside","CC1OC(OCC2OC(OC3=C(OC4=C(C(=CC(=C4)O)O)C3=O)C5=CC(=C(O)C=C5)O)C(O)C(O)C2O)C(O)C(O)C1O",-1.158,6,10,6]
["S2351","Salicin","h2","L8000-07","in 10mM DMSO","COX","Neuronal Signaling","Salicin (Salicoside, Salicine) is a phenol β-glycosid produced from willow bark that shows anti-inflammatory effects. It is a natural, non-selective COX-1 and COX-2 inhibitor.",286.28,"138-52-3",{"v":57,"d":"57.00"},199.11,{"v":24,"d":"24.00"},83.83,"http://selleckchem.com/products/Salicin(Salicoside,-Salicine).html","C13H18O7","free base","Salicoside,Salicine","OCC1OC(OC2=CC=CC=C2CO)C(O)C(O)C1O",-0.947,2,5,4]
["S2354","Sclareol","a3","L8000-07","in 10mM DMSO","Others","Others","Sclareol, a labdane-type diterpene isolated from clary sage (Salvia sclarea), exerts growth inhibition and cytotoxic activity against a variety of human cancer cell lines.",{"v":308.5,"d":"308.50"},"515-03-7",{"v":61,"d":"61.00"},197.73,"<1","N/A","http://selleckchem.com/products/Sclareol.html","C20H36O2","free base","N/A","CC1(C)CCCC2(C)C1CCC(C)(O)C2CCC(C)(O)C=C",{"v":4.27,"d":"4.270"},0,0,4]
["S2357","Silibinin (NSC 651520)","b3","L8000-07","in 10mM DMSO","Others","Others","Silibinin (NSC 651520, Silybin, Silibinin A, Silymarin I, Flavobin), the main flavonoid extracted from the milk thistle Silybum marianum, displays hepatoprotective properties in acute and chronic liver injury.",482.44,"22888-70-6",{"v":96,"d":"96.00"},198.99,"<1","N/A","http://selleckchem.com/products/Silibinin(Silybin).html","C25H22O10","free base","Silybin, Silibinin A, Silymarin I, Flavobin","COC1=CC(=CC=C1O)C2OC3=CC(=CC=C3OC2CO)C4OC5=CC(=CC(=C5C(=O)C4O)O)O",2.592,5,5,4]
["S2358","Silymarin","c3","L8000-07","in 10mM DMSO","Antioxidant","Angiogenesis","Silymarin (Silybin B), a polyphenolic flavonoid extracted from the seeds of Silybum marianum or milk thistle, is used in the prevention and treatment of liver diseases and primary liver cancer.",482.44,"65666-07-1",{"v":96,"d":"96.00"},198.99,"<1","N/A","http://selleckchem.com/products/Silymarin(Silybin-B).html","C25H22O10","free base","Silybin B","COC1=CC(=CC=C1O)C2OC3=CC=C(C=C3OC2CO)C4OC5=C(C(=CC(=C5)O)O)C(=O)C4O",2.592,5,5,4]
["S2362","Synephrine","d3","L8000-07","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Synephrine (Oxedrine), a natural protoalkaloid in the extract of bitter orange and other citrus species, is commonly used for weight loss.",167.21,"94-07-5",{"v":33,"d":"33.00"},197.36,"<1","N/A","http://selleckchem.com/products/Synephrine(Oxedrine).html","C9H13NO2","free base","Oxedrine","CNCC(O)C1=CC=C(O)C=C1",0.615,0,3,3]
["S2364","Tanshinone I","e3","L8000-07","in 10mM DMSO","Phospholipase (e.g. PLA)","Metabolism","Tanshinone I, an active principle isolated from Salvia miltiorrhiza (Danshen), is structurally similar to tanshinone IIA and may possess similar cytotoxic effects on tumor cells.",276.29,"568-73-0",{"v":23,"d":"23.00"},83.25,"<1","N/A","http://selleckchem.com/products/Tanshinone-I.html","C18H12O3","free base","N/A","CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C(C)C=CC=C34",4.084,3,0,0]
["S2365","Tanshinone IIA","f3","L8000-07","in 10mM DMSO","Lipase","Metabolism","Tanshinone IIA (Tanshinone B) is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae Radix, a widely prescribed traditional herbal medicine that is used to treat cardiovascular and inflammatory diseases; A natural monoacylglycerol lipase inhibitor.",294.34,"568-72-9",{"v":5,"d":"5.00"},16.99,"<1","N/A","http://selleckchem.com/products/Tanshinone-IIA(Tanshinone-B).html","C19H18O3","free base","Tanshinone B","CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C",{"v":4.66,"d":"4.660"},3,0,0]
["S2366","Taxifolin (Dihydroquercetin)","g3","L8000-07","in 10mM DMSO","VEGFR","Angiogenesis","Taxifolin, type I inhibitor for VEGFR-2 kinase, is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.",304.25,"480-18-2",{"v":60,"d":"60.00"},197.21,"<1","N/A","http://selleckchem.com/products/Taxifolin(Dihydroquercetin).html","C15H12O7","free base","N/A","OC1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(O)C=C3)O",1.479,2,5,1]
["S2369","Troxerutin","h3","L8000-07","in 10mM DMSO","NLR,ROS","Immunology & Inflammation","Troxerutin, a natural bioflavonoid isolated from Sophora japonica, has been reported to have many benefits and medicinal properties. Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation.",742.68,"7085-55-4",{"v":100,"d":"100.00"},134.65,{"v":100,"d":"100.00"},134.65,"http://selleckchem.com/products/Troxerutin.html","C33H42O19","free base","N/A","CC1OC(OCC2OC(OC3=C(OC4=CC(=CC(=C4C3=O)O)OCCO)C5=CC(=C(OCCO)C=C5)OCCO)C(O)C(O)C2O)C(O)C(O)C1O",{"v":-2.1,"d":"-2.100"},9,10,15]
["S2370","Ursolic Acid","a4","L8000-07","in 10mM DMSO","Others","Others","Ursolic acid (NSC 167406, NSC-4060, Prunol, Urson, Malol) is a pentacyclic triterpene acid, used in cosmetics.",{"v":456.7,"d":"456.70"},"77-52-1",{"v":91,"d":"91.00"},199.26,"<1","N/A","http://selleckchem.com/products/Ursolic-acid(Malol).html","C30H48O3","free base","NSC 167406, NSC-4060, Prunol, Urson, Malol","CC1CC(C2CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC34C)C2C1C)C(O)=O",6.327,1,1,1]
["S2375","Aloin","b4","L8000-07","in 10mM DMSO","Tyrosinase","Proteases","Aloin (Barbaloin, Barbalin), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.",418.39,"1415-73-2",{"v":83,"d":"83.00"},198.38,{"v":83,"d":"83.00"},198.38,"http://selleckchem.com/products/Aloin(Barbaloin).html","C21H22O9","free base","Barbaloin, Barbalin","OCC1OC(C(O)C(O)C1O)C2C3=C(C(=CC=C3)O)C(=O)C4=C2C=C(CO)C=C4O",-0.404,2,7,3]
["S2376","Ammonium Glycyrrhizinate","c4","L8000-07","in 10mM DMSO","Dehydrogenase,High-mobility Group","Metabolism","Ammonium Glycyrrhizinate (AMGZ, Glycyram, Glycyrrhizin ammonium salt, Glycyrrhizic acid ammonium salt) is a unique product from Licorice root with a very high sweetness. Ammonium glycyrrhizinate is a direct inhibitor of HMGB1 with anti-inflammatory, anti-tumor, anti-diabetic activities. Ammonium Glycyrrhizinate inhibits growth and cytopathology of several unrelated DNA and RNA viruses. Ammonium Glycyrrhizinate also inhibits both hepatic delta 4-5-reductase and 11 beta-hydroxysteroid dehydrogenase.",839.96,"1407-03-0",{"v":168,"d":"168.00"},200.01,{"v":5,"d":"5.00"},5.95,"http://selleckchem.com/products/Ammonium-Glycyrrhizinate(AMGZ).html","C42H62O16.NH3","Glycyrrhizic acid salt","AMGZ, Glycyram, Glycyrrhizin ammonium salt, Glycyrrhizic acid ammonium salt","N.CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O)OC6OC(C(O)C(O)C6OC7OC(C(O)C(O)C7O)C(O)=O)C(O)=O",-0.915,8,5,7]
["S2378","Butylscopolamine Bromide","d4","L8000-07","in 10mM DMSO","AChR","Neuronal Signaling","Butylscopolamine Bromide (Scopolamine Butylbromide,(-)-Scopolamine butylbromide, Hyoscine butylbromide), is a peripherally acting antimuscarinic, anticholinergic agent used as an abdominal-specific antispasmodic.",440.37,"149-64-4",{"v":88,"d":"88.00"},199.83,{"v":88,"d":"88.00"},199.83,"http://selleckchem.com/products/butylscopolamine-bromide.html","C21H30NO4.Br","Bromide","Scopolamine Butylbromide,(-)-Scopolamine butylbromide, Hyoscine butylbromide","[Br-].CCCC[N+]1(C)C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",{"v":-1.62,"d":"-1.620"},3,1,8]
["S2379","Dioscin","e4","L8000-07","in 10mM DMSO","Others","Others","Dioscin (Collettiside III, Saponin) is a saponin extracted and isolated from Polygonatum Zanlanscianense Pamp, showing antitumor activities.",869.04,"19057-60-4",{"v":100,"d":"100.00"},115.07,"<1","N/A","http://selleckchem.com/products/Dioscin(Collettiside-III).html","C45H72O16","free base","Collettiside III, Saponin","CC1CCC2(OC1)OC3CC4C5CC=C6CC(CCC6(C)C5CCC4(C)C3C2C)OC7OC(CO)C(OC8OC(C)C(O)C(O)C8O)C(O)C7OC9OC(C)C(O)C(O)C9O",1.169,8,8,7]
["S2380","Diosmetin","f4","L8000-07","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Diosmetin (Luteolin 4-methyl ether) is a bioflavonoid found in spearmint, oregano, and many other plants.",300.26,"520-34-3",{"v":60,"d":"60.00"},199.83,"<1","N/A","http://selleckchem.com/products/Diosmetin(Luteolin-4-methyl-ether).html","C16H12O6","free base","Luteolin 4-methyl ether","COC1=CC=C(C=C1O)C2=CC(=O)C3=C(O)C=C(O)C=C3O2",2.394,3,3,2]
["S2382","Evodiamine","g4","L8000-07","in 10mM DMSO","NF-κB","NF-κB","Evodiamine (Isoevodiamine), an alkaloid extract from the fruit of Evodiae Fructus exhibits antitumor activities against the human tumor cells. It is shown to inhibit NF-kB activation through suppression of IkB kinase activity.",303.36,"518-17-2",{"v":12,"d":"12.00"},39.56,"<1","N/A","http://www.selleck.cn/products/Evodiamine(Isoevodiamine).html","C19H17N3O","Free Base","Isoevodiamine","CN1C2N(CCC3=C2[NH]C4=CC=CC=C34)C(=O)C5=C1C=CC=C5",3.673,1,1,0]
["S2383","Gastrodin","h4","L8000-07","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Gastrodin (Gastrodine), an anti-inflammatory polyphenol extracted from Chinese natural herbal Gastrodia elata Blume., benefits neurodegenerative diseases.",286.28,"62499-27-8",{"v":50,"d":"50.00"},174.65,"<1","N/A","http://selleckchem.com/products/Gastrodin(Gastrodine).html","C13H18O7","free base","Gastrodine","OCC1OC(OC2=CC=C(CO)C=C2)C(O)C(O)C1O",-0.947,2,5,4]
["S2386","Indirubin (NSC 105327)","a5","L8000-07","in 10mM DMSO","GSK-3","PI3K/Akt/mTOR","Indirubin (NSC 105327) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 μM and 0.6 μM.",262.26,"479-41-4",{"v":53,"d":"53.00"},202.09,"<1","N/A","http://selleckchem.com/products/Indirubin.html","C16H10N2O2","free base","NSC 105327","O=C1NC2=CC=CC=C2\\C1=C3/NC4=C(C=CC=C4)C3=O",1.876,2,2,0]
["S2387","Lappaconite HBr","b5","L8000-07","in 10mM DMSO","ADC Cytotoxin,Immunology & Inflammation related","Immunology & Inflammation","Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects.",665.61,"97792-45-5",{"v":28,"d":"28.00"},42.07,"<1","N/A","http://selleckchem.com/products/Lappaconite-Hydrobromide.html","C32H44N2O8.HBr","Hydrobromide","N/A","Br.CCN1CC2(CCC(OC)C34C2CC(C13)C5(O)CC(OC)C6CC4C5(O)C6OC)OC(=O)C7=C(NC(C)=O)C=CC=C7",{"v":0.52,"d":"0.520"},6,1,8]
["S2388","L-carnitine","c5","L8000-07","in 10mM DMSO","Others","Others","L-carnitine (Levocarnitine,Carnitor, vitamin BT, Karnitin,L(-)-Carnitine) is constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.",{"v":161.2,"d":"161.20"},"541-15-1",{"v":12,"d":"12.00"},74.44,{"v":32,"d":"32.00"},198.51,"http://selleckchem.com/products/L-carnitine(Levocarnitine).html","C7H15NO3","quaternary-N  salt","Levocarnitine,Carnitor, vitamin BT, Karnitin,L(-)-Carnitine","C[N+](C)(C)CC(O)CC([O-])=O",{"v":-3.29,"d":"-3.290"},0,1,4]
["S2389","Naringin Dihydrochalcone","d5","L8000-07","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Naringin Dihydrochalcone(Naringin DC) is a new-style sweetening agent and an artificial sweetener derived from naringin and also an inhibitor of CYP enzymes.",582.55,"18916-17-1",{"v":100,"d":"100.00"},171.66,"<1","N/A","http://selleckchem.com/products/Naringin-Dihydrochalcone(Naringin-DC).html","C27H34O14","free base","N/A","CC1OC(OC2C(O)C(O)C(CO)OC2OC3=CC(=C(C(=O)CCC4=CC=C(O)C=C4)C(=C3)O)O)C(O)C(O)C1O",-0.032,5,9,9]
["S2390","Polydatin","e5","L8000-07","in 10mM DMSO","Phospholipase (e.g. PLA)","Metabolism","Polydatin (Piceid) is a crystal component extracted from the root stem of perennial herbage Polygonum Cuspidatum Sieb.et Zucc.",390.38,"65914-17-2",{"v":78,"d":"78.00"},199.81,"<1","N/A","http://selleckchem.com/products/Polydatin(Piceid).html","C20H22O8","free base","Piceid","OCC1OC(OC2=CC(=CC(=C2)\\C=C\\C3=CC=C(O)C=C3)O)C(O)C(O)C1O",{"v":1.16,"d":"1.160"},2,6,5]
["S2391","Quercetin (NSC 9221)","f5","L8000-07","in 10mM DMSO","Apoptosis related,Autophagy,Mitophagy,PI3K,PKC,Sirtuin,Src","Epigenetics","Quercetin (NSC 9221, Sophoretin, C.I. 75720), a natural flavonoid present in vegetables, fruit and wine, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4-5.4 μM. Quercetin induces mitophagy, apoptosis and protective autophagy. Phase 4.",302.24,"117-39-5",{"v":61,"d":"61.00"},201.83,"<1","N/A","http://selleckchem.com/products/Quercetin(Sophoretin).html","C15H10O7","Free Base","Sophoretin, C.I. 75720","OC1=CC(=C2C(=O)C(=C(OC2=C1)C3=CC=C(O)C(=C3)O)O)O",{"v":1.63,"d":"1.630"},2,5,1]
["S2396","Salidroside","g5","L8000-07","in 10mM DMSO","Mitophagy,mTOR,PREP","PI3K/Akt/mTOR","Salidroside (Rhodioloside), a phenylpropanoid glycoside isolated from Rhodiola rosea, has been reported to have a broad spectrum of pharmacological properties. Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.",{"v":300.3,"d":"300.30"},"10338-51-9",{"v":60,"d":"60.00"},{"v":199.8,"d":"199.80"},{"v":60,"d":"60.00"},{"v":199.8,"d":"199.80"},"http://selleckchem.com/products/Salidroside-Rhodioloside.html","C14H20O7","free base","Rhodioloside","OCC1OC(OCCC2=CC=C(O)C=C2)C(O)C(O)C1O",-0.443,2,5,5]
["S2397","Palmatine chloride","h5","L8000-07","in 10mM DMSO","Calcium Channel","Neuronal Signaling","Palmatine hydrochloride (Palmatine chloride (6CI,7CI); Fibrauretin) is a hydrochloride salt of palmatine which is a protoberberine alkaloid.",387.86,"10605-02-4",{"v":77,"d":"77.00"},198.53,{"v":5,"d":"5.00"},12.89,"http://selleckchem.com/products/Palmatine-chloride.html","C21H22NO4.Cl","Chloride","N/A","[Cl-].COC1=CC=C2C=C3C4=C(CC[N+]3=CC2=C1OC)C=C(OC)C(=C4)OC",1.488,4,0,4]
["S2401","Sodium Danshensu","a6","L8000-07","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Sodium Danshensu is a mono sodium of danshensu, which is a natural phenolic acid of caffeic acid derivatives isolated from Salvia miltiorrhiza.",220.15,"67920-52-9",{"v":7,"d":"7.00"},{"v":31.8,"d":"31.80"},{"v":2,"d":"2.00"},9.08,"http://selleckchem.com/products/Sodium-Danshensu.html","C9H9O5.Na","Sodium Salt","N/A","[Na+].OC(CC1=CC(=C(O)C=C1)O)C([O-])=O",-0.795,0,3,3]
["S2403","Tetrandrine (NSC-77037)","b6","L8000-07","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Tetrandrine (NSC-77037, Fanchinine, d-Tetrandrine), a bis-benzylisoquinoline alkaloid derived from Stephania tetrandra, is a calcium channel blocker.",622.75,"518-34-3",{"v":7,"d":"7.00"},11.24,"<1","N/A","http://www.selleck.cn/products/Tetrandrine-Fanchinine.html","C38H42N2O6","Free Base","Fanchinine, d-Tetrandrine","COC1=CC=C2CC3N(C)CCC4=CC(=C(OC)C(=C34)OC5=C(OC)C=C6CCN(C)C(CC7=CC=C(OC1=C2)C=C7)C6=C5)OC",7.218,6,0,4]
["S2422","Ipriflavone (Osteofix)","c6","L8000-07","in 10mM DMSO","Others","Others","Ipriflavone (7-Isopropoxyisoflavon) is used to inhibit bone resorption.",280.32,"35212-22-7",{"v":56,"d":"56.00"},199.77,"<1","N/A","http://selleckchem.com/products/ipriflavone.html","C18H16O3","free base","N/A","CC(C)OC1=CC=C2C(=C1)OC=C(C2=O)C3=CC=CC=C3",3.576,3,0,3]
["S2423","(S)-10-Hydroxycamptothecin","d6","L8000-07","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor with potent anti-tumor activity.",364.35,"19685-09-7",{"v":8,"d":"8.00"},21.96,"<1","N/A","http://selleckchem.com/products/10-hydroxycamptothecin.html","C20H16N2O5","free base","10-HCPT","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=CC5=CC(=CC=C5N=C34)O)C2=O",1.504,4,1,1]
["S2438","Synephrine HCl","e6","L8000-07","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","SynephrineHCl (Oxedrine, p-Synephrine) is a sympathomimetic α-adrenergic receptor (AR) agonist.",203.67,"5985-28-4",{"v":14,"d":"14.00"},68.74,{"v":41,"d":"41.00"},201.31,"http://selleckchem.com/products/synephrine-hcl.html","C9H13NO2.HCl","Hydrochloride","N/A","Cl.CNCC(O)C1=CC=C(O)C=C1",0.997,0,3,3]
["S2439","Guanosine","f6","L8000-07","in 10mM DMSO","Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond.",283.24,"118-00-3",{"v":56,"d":"56.00"},197.71,"<1","N/A","http://selleckchem.com/products/guanosine.html","C10H13N5O5","free base","N/A","NC1=NC2=C(N=C[N]2C3OC(CO)C(O)C3O)C(=O)N1",{"v":-2.38,"d":"-2.380"},4,5,2]
["S2443","Tolbutamide (HLS 831)","g6","L8000-07","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Tolbutamide (HLS 831) is an inhibitor of potassium channel, used for type II diabetes.",270.35,"64-77-7",{"v":54,"d":"54.00"},199.74,"<1","N/A","http://selleckchem.com/products/tolbutamide.html","C12H18N2O3S","free base","HLS 831","CCCCNC(=O)N[S](=O)(=O)C1=CC=C(C)C=C1",2.336,3,2,5]
["S2450","Equol","h6","L8000-07","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Equol ,a metabolite of soybeans, is an important isoflavone in humans，specifically binds to 5α-DHT, has a modest affinity for recombinant estrogen receptor ERβ. Phase 2.",242.27,"531-95-3",{"v":48,"d":"48.00"},198.13,"<1","N/A","http://selleckchem.com/products/equol.html","C15H14O3","free base","N/A","OC1=CC=C(C=C1)C2COC3=CC(=CC=C3C2)O",3.211,1,2,1]
["S2455","Bethanechol chloride","a7","L8000-07","in 10mM DMSO","AChR","Neuronal Signaling","Bethanechol chloride(Myocholine,Urecholine) is a selective muscarinic receptor agonist without any effect on nicotinic receptors.",196.68,"590-63-6",{"v":39,"d":"39.00"},198.29,{"v":39,"d":"39.00"},198.29,"http://selleckchem.com/products/Carbamyl-beta-methylcholine-chloride(Bethanechol-chloride).html","C7H17N2O2.Cl","quaternary-N Chloride salt","Myocholine,Urecholine","[Cl-].CC(C[N+](C)(C)C)OC(N)=O",-3.702,2,1,4]
["S2456","Chlorpromazine HCl","b7","L8000-07","in 10mM DMSO","Dopamine Receptor,Potassium Channel","Neuronal Signaling","Chlorpromazine HCl (Sonazine) is a dopamine and potassium channel inhibitor with IC50 of 6.1 and 16 μM for inward-rectifying K+ currents and time-independent outward currents.",355.33,"69-09-0",{"v":71,"d":"71.00"},199.81,{"v":71,"d":"71.00"},199.81,"http://selleckchem.com/products/Chlorpromazine-hydrochloride(Sonazine).html","C17H19ClN2S.HCl","Hydrochloride","Sonazine","Cl.CN(C)CCCN1C2=C(SC3=C1C=C(Cl)C=C3)C=CC=C2",5.121,0,0,4]
["S2458","Clonidine HCl","c7","L8000-07","in 10mM DMSO","Adrenergic Receptor,Autophagy","Neuronal Signaling","Clonidine HCl(Kapvay) is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg.",{"v":266.5,"d":"266.50"},"4205-91-8",{"v":53,"d":"53.00"},198.87,{"v":53,"d":"53.00"},198.87,"http://selleckchem.com/products/Clonidine-hydrochloride(Catapres).html","C9H9Cl2N3.HCl","Hydrochloride","Kapvay","Cl.ClC1=C(NC2=NCCN2)C(=CC=C1)Cl",2.736,1,2,2]
["S2461","Domperidone","d7","L8000-07","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Domperidone is an oral dopamine D2 receptor antagonist, used to treat nausea and vomiting.",425.91,"57808-66-9",{"v":48,"d":"48.00"},{"v":112.7,"d":"112.70"},"<1","N/A","http://selleckchem.com/products/Domperidone(Motilium).html","C22H24ClN5O2","free base","N/A","ClC1=CC2=C(C=C1)N(C3CCN(CCCN4C(=O)NC5=C4C=CC=C5)CC3)C(=O)N2",2.453,2,2,5]
["S2466","Estriol","e7","L8000-07","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estriol (NSC-12169) is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.",288.39,"50-27-1",{"v":57,"d":"57.00"},197.65,"<1","N/A","http://selleckchem.com/products/Estriol(Oestriol).html","C18H24O3","free base","NSC-12169","CC12CCC3C(CCC4=CC(=CC=C34)O)C1CC(O)C2O",2.871,0,3,0]
["S2467","Famciclovir","f7","L8000-07","in 10mM DMSO","Antiviral","Microbiology","Famciclovir (BRL-42810) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.",321.34,"104227-87-4",{"v":64,"d":"64.00"},199.17,{"v":64,"d":"64.00"},199.17,"http://selleckchem.com/products/Famciclovir(Famvir).html","C14H19N5O4","free base","BRL-42810","CC(=O)OCC(CC[N]1C=NC2=CN=C(N)N=C12)COC(C)=O",-0.294,7,1,9]
["S2468","Fenbendazole","g7","L8000-07","in 10mM DMSO","Parasite","Microbiology","Fenbendazole(Fenbendazol,Phenbendasol) is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL.",299.35,"43210-67-9",{"v":4,"d":"4.00"},13.36,"<1","N/A","http://selleckchem.com/products/Fenbendazole(Panacur).html","C15H13N3O2S","free base","Fenbendazol,Phenbendasol","COC(=O)NC1=NC2=C([NH]1)C=C(SC3=CC=CC=C3)C=C2",3.769,3,2,4]
["S2470","Fluocinolone Acetonide","h7","L8000-07","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Fluocinolone Acetonide (Flucort-N) is a corticosteroid that binds to the cytosolic glucocorticoid receptor.",{"v":452.5,"d":"452.50"},"67-73-2",{"v":90,"d":"90.00"},{"v":198.9,"d":"198.90"},"<1","N/A","http://selleckchem.com/products/Fluocinolone-acetonide(Flucort-N).html","C24H30F2O6","free base","Flucort-N","CC1(C)OC2CC3C4CC(F)C5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(O1)C(=O)CO",0.995,4,2,2]
["S2471","Gallamine Triethiodide","a8","L8000-07","in 10mM DMSO","AChR","Neuronal Signaling","Gallamine Triethiodide  is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM.",891.53,"65-29-2",{"v":100,"d":"100.00"},112.17,{"v":100,"d":"100.00"},112.17,"http://selleckchem.com/products/Gallamine-triethiodide(Flaxedil).html","C30H60I3N3O3","tri-quaternary-N iodide salt","N/A","[I-].[I-].[I-].CC[N+](CC)(CC)CCOC1=C(OCC[N+](CC)(CC)CC)C(=CC=C1)OCC[N+](CC)(CC)CC",-8.065,3,0,21]
["S2473","Hexestrol","b8","L8000-07","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Hexestrol (Bibenzyl) binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.",270.37,"84-16-2",{"v":42,"d":"42.00"},155.34,"<1","N/A","http://selleckchem.com/products/Hexestrol(Bibenzyl).html","C18H22O2","free base","Bibenzyl","CCC(C(CC)C1=CC=C(O)C=C1)C2=CC=C(O)C=C2",5.192,0,2,5]
["S2475","Imatinib (STI571)","c8","L8000-07","in 10mM DMSO","Autophagy,Bcr-Abl,c-Kit,PDGFR","Protein Tyrosine Kinase","Imatinib (STI571,Gleevec, Glivec, CGP057148B) is a multi-target inhibitor of tyrosine kinase with inhibition for v-Abl, c-Kit and PDGFR, IC50 values are 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib (STI571) induces autophagy.",{"v":493.6,"d":"493.60"},"152459-95-5",{"v":33,"d":"33.00"},66.86,"<1","N/A","http://selleckchem.com/products/Imatinib(STI571).html","C29H31N7O","free base","STI571,Gleevec, Glivec, CGP057148B","CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC=C(C)C(=C3)NC4=NC=CC(=N4)C5=CC=CN=C5",{"v":4.22,"d":"4.220"},4,2,7]
["S2480","Loperamide HCl","d8","L8000-07","in 10mM DMSO","Autophagy,Opioid Receptor","Neuronal Signaling","Loperamide HCl (ADL 2-1294,R-18553 hydrochloride) is a selective μ-opioid receptor agonist opioid with Ki of 3.3 nM, 15-fold and 350-fold selective over the δ subtype and the κ subtype of the opioid receptor, used against diarrhea resulting from gastroenteritis or inflammatory bowel disease.",{"v":513.5,"d":"513.50"},"34552-83-5",{"v":22,"d":"22.00"},42.84,"<1","N/A","http://selleckchem.com/products/Loperamide-hydrochloride.html","C29H33ClN2O2.HCl","Hydrochloride","ADL 2-1294,R-18553 hydrochloride","Cl.CN(C)C(=O)C(CCN1CCC(O)(CC1)C2=CC=C(Cl)C=C2)(C3=CC=CC=C3)C4=CC=CC=C4",5.017,1,0,7]
["S2481","Manidipine","e8","L8000-07","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Manidipine(CV-4093,(±)-Manidipine) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive.",{"v":610.7,"d":"610.70"},"89226-50-6",{"v":122,"d":"122.00"},199.77,"<1","N/A","http://selleckchem.com/products/Manidipine(Manyper).html","C35H38N4O6","free base","CV-4093,(±)-Manidipine","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OCCN3CCN(CC3)C(C4=CC=CC=C4)C5=CC=CC=C5)C",5.058,4,1,12]
["S2484","Milrinone","f8","L8000-07","in 10mM DMSO","PDE","Metabolism","Milrinone (Win 47203,Primacor) is a phosphodiesterase 3 (PDE3) inhibitor, used to increase the heart's contractility.",211.22,"78415-72-2",{"v":42,"d":"42.00"},198.84,"<1","N/A","http://selleckchem.com/products/Milrinone(Primacor).html","C12H9N3O","free base","Win 47203,Primacor","CC1=C(C=C(C#N)C(=O)N1)C2=CC=NC=C2",0.356,2,1,1]
["S2485","Mitoxantrone (NSC-301739) 2HCl","g8","L8000-07","in 10mM DMSO","Apoptosis related,COVID-19,PKC,Topoisomerase","DNA Damage/DNA Repair","Mitoxantrone 2HCl (NSC-301739) is a dihydrochloride salt of Mitoxantrone. Mitoxantrone is an inhibitor of type II topoisomerase and protein kinase C (PKC) with IC50 of 8.5 μM for PKC. Mitoxantrone inhibits cell proliferative growth of MCF-7/wt cells with IC50 of 0.42 μM. Mitoxantrone also induces apoptosis.",{"v":517.4,"d":"517.40"},"70476-82-3",{"v":89,"d":"89.00"},172.01,{"v":89,"d":"89.00"},172.01,"http://selleckchem.com/products/Mitoxantrone-Hydrochloride.html","C22H29ClN4O6.2HCl","Dihydrochloride","NSC-301739 2HCl","Cl.Cl.OCCNCCNC1=CC=C(NCCNCCO)C2=C1C(=O)C3=C(O)C=CC(=C3C2=O)O",0.832,2,8,12]
["S2486","Moroxydine HCl","h8","L8000-07","in 10mM DMSO","Antiviral","Microbiology","Moroxydine HCl(ABOB hydrochloride) is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines.",207.66,"3160-91-6",{"v":42,"d":"42.00"},202.25,{"v":42,"d":"42.00"},202.25,"http://selleckchem.com/products/Moroxydine-hydrochloride.html","C6H13N5O.HCl","Hydrochloride","ABOB hydrochloride","Cl.NC(=N)NC(=N)N1CCOCC1",-0.672,1,2,3]
["S2487","Mycophenolic acid","a9","L8000-07","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,Dehydrogenase,Selection Antibiotics for Transfected Cell","Metabolism","Mycophenolic acid (Mycophenolate, RS-61443) is a potent IMPDH inhibitor and the active metabolite of an immunosuppressive drug, used to prevent rejection in organ transplantation.",320.34,"24280-93-1",{"v":64,"d":"64.00"},199.79,"<1","N/A","http://selleckchem.com/products/Mycophenolic-acid(Mycophenolate).html","C17H20O6","free base","Mycophenolate, RS-61443","COC1=C(C)C2=C(C(=C1C\\C=C(/C)CCC(O)=O)O)C(=O)OC2",3.157,4,1,6]
["S2489","Nateglinide","b9","L8000-07","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Nateglinide (Starlix,A-4166,SDZ DJN 608) is an insulin secretagog agent that lowers blood glucose levels by stimulating insulin secretion from the pancreas.",317.42,"105816-04-4",{"v":63,"d":"63.00"},198.48,"<1","N/A","http://selleckchem.com/products/Nateglinide(Starlix).html","C19H27NO3","free base","Starlix,A-4166,SDZ DJN 608","CC(C)C1CCC(CC1)C(=O)NC(CC2=CC=CC=C2)C(O)=O",3.981,2,1,6]
["S2492","Novobiocin Sodium (NSC 2382)","c9","L8000-07","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,Topoisomerase","DNA Damage/DNA Repair","Novobiocin Sodium (NSC 2382, Albamycin, Cathomycin) is an aminocoumarin antibiotic that targets bacterial DNA gyrase (TopoIV), used to treat susceptible gram positive bacteria.",634.61,"1476-53-5",{"v":100,"d":"100.00"},157.58,{"v":100,"d":"100.00"},157.58,"http://selleckchem.com/products/Novobiocin-sodium(Albamycin).html","C31H35N2O11.Na","Sodium Salt","Albamycin,Cathomycin,NSC 2382","[Na+].COC1C(OC(N)=O)C(O)C(OC2=CC=C3C(=C(NC(=O)C4=CC=C([O-])C(=C4)CC=C(C)C)C(=O)OC3=C2C)O)OC1(C)C",2.747,8,4,9]
["S2493","Olanzapine","d9","L8000-07","in 10mM DMSO","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Olanzapine (LY170053,Zyprexa, Zalasta, Zolafren, Olzapin, Oferta, Zypadhera) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist.",312.44,"132539-06-1",{"v":62,"d":"62.00"},198.44,"<1","N/A","http://selleckchem.com/products/Olanzapine(Zyprexa).html","C17H20N4S","free base","LY170053,Zyprexa, Zalasta, Zolafren, Olzapin, Oferta, Zypadhera","CN1CCN(CC1)C2=NC3=C(NC4=C2C=C(C)S4)C=CC=C3",{"v":2.69,"d":"2.690"},1,1,1]
["S2494","Olopatadine HCl","e9","L8000-07","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Olopatadine HCl(ALO4943A,KW4679) is a histamine blocker and mast cell stabilizer with an IC50 of 559 μM for the release of histamine.",373.87,"140462-76-6",{"v":75,"d":"75.00"},{"v":200.6,"d":"200.60"},{"v":13,"d":"13.00"},34.77,"http://selleckchem.com/products/Olopatadine-hydrochloride(Opatanol).html","C21H23NO3.HCl","Hydrochloride","ALO4943A,KW4679","Cl.CN(C)CC\\C=C/1C2=C(COC3=C1C=C(CC(O)=O)C=C3)C=CC=C2",{"v":0.92,"d":"0.920"},2,0,5]
["S2496","Ozagrel","f9","L8000-07","in 10mM DMSO","P450 (e.g. CYP17),Prostaglandin Receptor","GPCR & G Protein","Ozagrel (OKY-046) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.",228.25,"82571-53-7",{"v":46,"d":"46.00"},201.53,"<1","N/A","http://selleckchem.com/products/Ozagrel.html","C13H12N2O2","free base","OKY-046","OC(=O)/C=C/C1=CC=C(C[N]2C=CN=C2)C=C1",1.604,2,0,4]
["S2497","Pancuronium dibromide","g9","L8000-07","in 10mM DMSO","AChR","Neuronal Signaling","Pancuronium dibromide(Pavulon) is a competitive nicotinic acetylcholine receptor antagonist, used as a muscle relaxant.",732.67,"15500-66-0",{"v":100,"d":"100.00"},136.49,{"v":100,"d":"100.00"},136.49,"http://selleckchem.com/products/Pancuronium-bromide(Pavulon).html","C35H60N2O4.2Br","di-quaternary-N bromide salt","Pavulon","[Br-].[Br-].CC(=O)OC1CC2CCC3C(CCC4(C)C3CC(C4OC(C)=O)[N+]5(C)CCCCC5)C2(C)CC1[N+]6(C)CCCCC6",-2.043,4,0,6]
["S2499","Phenoxybenzamine HCl","h9","L8000-07","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Phenoxybenzamine HCl (NSC 37448, NCI-c01661) is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.",{"v":340.3,"d":"340.30"},"63-92-3",{"v":68,"d":"68.00"},199.82,{"v":17,"d":"17.00"},49.96,"http://selleckchem.com/products/Phenoxybenzamine-hydrochloride.html","C18H22ClNO.HCl","HCl","NSC 37448, NCI-c01661","Cl.CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2",{"v":4.96,"d":"4.960"},1,0,8]
["S2502","Quinine HCl Dihydrate","a10","L8000-07","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Quinine HCl Dihydrate is a white crystalline K+ channel blocker, used to treat malaria.",396.91,"6119-47-7",{"v":79,"d":"79.00"},199.04,{"v":43,"d":"43.00"},108.34,"http://selleckchem.com/products/Quinine-hydrochloride-dihydrate.html","C20H24N2O2.HCl.2H2O","Hydrochloride dihydrate","N/A","O.O.Cl.COC1=CC2=C(C=C1)N=CC=C2C(O)C3CC4CCN3CC4C=C",2.701,2,1,4]
["S2503","Racecadotril","b10","L8000-07","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","Racecadotril (Acetorphan) is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 μM.",385.48,"81110-73-8",{"v":22,"d":"22.00"},57.07,"<1","N/A","http://selleckchem.com/products/Racecadotril(Acetorphan).html","C21H23NO4S","free base","Acetorphan","CC(=O)SCC(CC1=CC=CC=C1)C(=O)NCC(=O)OCC2=CC=CC=C2",3.128,4,1,11]
["S2504","Ribavirin (ICN-1229)","c10","L8000-07","in 10mM DMSO","Antiviral","Microbiology","Ribavirin (NSC-163039, ICN-1229, RTCA, Tribavirin), a synthetic guanosine analogue, possesses a broad spectrum of activity against DNA and RNA viruses.",244.21,"36791-04-5",{"v":49,"d":"49.00"},200.65,{"v":49,"d":"49.00"},200.65,"http://selleckchem.com/products/Ribavirin(Copegus).html","C8H12N4O5","free base","NSC-163039, RTCA, Tribavirin","NC(=O)C1=N[N](C=N1)C2OC(CO)C(O)C2O",-2.745,4,4,3]
["S2505","Rosiglitazone (BRL-49653) maleate","d10","L8000-07","in 10mM DMSO","Autophagy,Ferroptosis,PPAR,TRP Channel","Metabolism","Rosiglitazone maleate (BRL-49653C), a member of the thiazolidinedione class of antihyperglycaemic agents, is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-γ (PPAR-γ) with IC50 of 42 nM. Rosiglitazone maleate also modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis.",{"v":473.5,"d":"473.50"},"155141-29-0",{"v":94,"d":"94.00"},198.52,"<1","N/A","http://selleckchem.com/products/Rosiglitazone-maleate.html","C18H19N3O3S.C4H4O4","Maleate","BRL-49653C","CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C3=NC=CC=C3.OC(=O)\\C=C/C(O)=O",3.307,6,1,9]
["S2508","Scopolamine (LSM-4015) HBr","e10","L8000-07","in 10mM DMSO","AChR","Neuronal Signaling","Scopolamine HBr (LSM-4015,NSC 61806,(-)-Scopolamine hydrobromide, Hyoscine hydrobromide, Scopine hydrobromide) is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55.3 nM.",384.26,"114-49-8",{"v":76,"d":"76.00"},197.78,{"v":76,"d":"76.00"},197.78,"http://selleckchem.com/products/Scopolamine-hydrobromide.html","C17H21NO4.HBr","Hydrobromide","LSM-4015,NSC 61806,(-)-Scopolamine hydrobromide, Hyoscine hydrobromide, Scopine hydrobromide","Br.CN1C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",1.314,3,1,5]
["S2509","Sotalol HCl","f10","L8000-07","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Sotalol(MJ-1999)  is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 μM.",308.82,"959-24-0",{"v":61,"d":"61.00"},197.53,{"v":61,"d":"61.00"},197.53,"http://selleckchem.com/products/Sotalol-hydrochloride(Betapace).html","C12H20N2O3S.HCl","Hydrochloride","MJ-1999","Cl.CC(C)NCC(O)C1=CC=C(N[S](C)(=O)=O)C=C1",0.876,2,3,6]
["S2511","Sulfadoxine","g10","L8000-07","in 10mM DMSO","Anti-infection","Microbiology","Sulfadoxine (Sulphadoxine) is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax.",310.33,"2447-57-6",{"v":62,"d":"62.00"},199.78,"<1","N/A","http://selleckchem.com/products/Sulfadoxine(Sulphadoxine).html","C12H14N4O4S","free base","Sulphadoxine","COC1=C(OC)C(=NC=N1)N[S](=O)(=O)C2=CC=C(N)C=C2",0.837,6,2,5]
["S2512","Tenoxicam","h10","L8000-07","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Tenoxicam(Ro-12-0068) is a good HO. radicals scavenger with an IC50 of 56.7 μM.",337.38,"59804-37-4",{"v":68,"d":"68.00"},201.55,"<1","N/A","http://selleckchem.com/products/Tenoxicam(Mobiflex).html","C13H11N3O4S2","free base","Ro-12-0068","CN1C(=C(O)C2=C(C=CS2)[S]1(=O)=O)C(=O)NC3=CC=CC=N3",0.454,4,2,2]
["S2515","Vardenafil HCl Trihydrate","a11","L8000-07","in 10mM DMSO","PDE","Metabolism","Vardenafil HCl Trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.",579.11,"330808-88-3",{"v":100,"d":"100.00"},172.68,{"v":10,"d":"10.00"},17.27,"http://selleckchem.com/products/Vardenafil(Vivanza).html","C23H32N6O4S.HCl.3H2O","Hydrochloride trihydrate","BAY38-9456","O.O.O.Cl.CCCC1=NC(=C2[N]1N=C(NC2=O)C3=CC(=CC=C3OCC)[S](=O)(=O)N4CCN(CC)CC4)C",2.109,6,1,8]
["S2516","Xylazine HCl","b11","L8000-07","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Xylazine(BAY 1470 hydrochloride) is an α2-Adrenergic receptor agonist, used as a sedative and muscle relaxant.",256.79,"23076-35-9",{"v":50,"d":"50.00"},194.71,{"v":12,"d":"12.00"},46.73,"http://selleckchem.com/products/Xylazine(Rompun).html","C12H16N2S.HCl","Hydrochloride","BAY 1470 hydrochloride","Cl.CC1=C(NC2=NCCCS2)C(=CC=C1)C",3.647,1,1,2]
["S2517","Maprotiline HCl","c11","L8000-07","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Maprotiline HCl is a selective noradrenalin re-uptake inhibitor, used in the treatment of depression.",313.86,"10347-81-6",{"v":63,"d":"63.00"},200.73,"<1","N/A","http://selleckchem.com/products/Maprotiline-hydrochloride.html","C20H23N.HCl","Hydrochloride","N/A","Cl.CNCCCC12CCC(C3=CC=CC=C13)C4=C2C=CC=C4",4.498,0,1,4]
["S2519","Naphazoline HCl","d11","L8000-07","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Naphazoline HCl is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.",246.74,"550-99-2",{"v":17,"d":"17.00"},{"v":68.9,"d":"68.90"},{"v":49,"d":"49.00"},198.59,"http://selleckchem.com/products/Naphazoline-hydrochloride-Naphcon.html","C14H14N2.HCl","Hydrochloride","N/A","Cl.C1CN=C(CC2=C3C=CC=CC3=CC=C2)N1",2.442,1,1,2]
["S2528","Ciclopirox","e11","L8000-07","in 10mM DMSO","ATPase,Fungal","Transmembrane Transporters","Ciclopirox(HOE 296b, Penlac) is a broad-spectrum antifungal agent working as an iron chelator.",207.27,"29342-05-0",{"v":42,"d":"42.00"},202.63,"<1","N/A","http://selleckchem.com/products/Ciclopirox-Penlac.html","C12H17NO2","Free Base","HOE 296b, Penlac","CC1=CC(=O)N(O)C(=C1)C2CCCCC2",2.489,1,0,1]
["S2529","Dopamine HCl","f11","L8000-07","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Dopamine HCl(ASL279, NSC 173182) is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.",189.64,"62-31-7",{"v":38,"d":"38.00"},200.38,{"v":38,"d":"38.00"},200.38,"http://selleckchem.com/products/Dopamine-hydrochloride-Inotropin.html","C8H11NO2.HCl","Hydrochloride","ASL279, NSC 173182","Cl.NCCC1=CC(=C(O)C=C1)O",1.155,0,3,2]
["S2533","Ritodrine HCl","g11","L8000-07","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Ritodrine HCl (NSC 291565,DU 21220, Ritodrine) is a hydrochloride salt of ritodrine which is a β-2 adrenergic receptor agonist.",323.81,"23239-51-2",{"v":65,"d":"65.00"},200.73,{"v":65,"d":"65.00"},200.73,"http://selleckchem.com/products/Ritodrine-hydrochloride-Yutopar.html","C17H21NO3.HCl","Hydrochloride","NSC 291565,DU 21220, Ritodrine","Cl.CC(NCCC1=CC=C(O)C=C1)C(O)C2=CC=C(O)C=C2",3.037,0,4,6]
["S2535","Econazole nitrate","h11","L8000-07","in 10mM DMSO","Calcium Channel,Fungal","Transmembrane Transporters","Econazole Nitrate (NSC 243115,Spectazole) is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus.",{"v":444.7,"d":"444.70"},"24169-02-6",{"v":89,"d":"89.00"},200.13,"<1","N/A","http://selleckchem.com/products/Econazole-nitrate-Spectazole.html","C18H15Cl3N2O.HNO3","Nitrate","NSC 243115,Spectazole","O[N+]([O-])=O.ClC1=CC=C(COC(C[N]2C=CN=C2)C3=CC=C(Cl)C=C3Cl)C=C1",3.722,2,0,6]
["S2536","Miconazole","a2","L8000-08","in 10mM DMSO","Fungal","Microbiology","Miconazole (Monistat,R18134) is an imidazole antifungal agent.",416.13,"22916-47-8",{"v":83,"d":"83.00"},199.46,"<1","N/A","http://selleckchem.com/products/Miconazole-Monistat.html","C18H14Cl4N2O","Free Base","Monistat,R18134","ClC1=CC=C(COC(C[N]2C=CN=C2)C3=C(Cl)C=C(Cl)C=C3)C(=C1)Cl",5.645,2,0,6]
["S2537","Secnidazole","b2","L8000-08","in 10mM DMSO","Anti-infection","Microbiology","Secnidazole (Flagentyl, PM 185184, RP 14539) is a nitroimidazole anti-infective.",185.18,"3366-95-8",{"v":37,"d":"37.00"},199.81,{"v":37,"d":"37.00"},199.81,"http://selleckchem.com/products/Secnidazole-Flagentyl.html","C7H11N3O3","free base","PM 185184, RP 14539","CC(O)C[N]1C(=NC=C1[N+]([O-])=O)C",{"v":0.04,"d":"0.040"},1,1,3]
["S2541","Clomipramine HCl","c2","L8000-08","in 10mM DMSO","Serotonin Transporter","Neuronal Signaling","Clomipramine HCl(Anafranil) is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively.",351.31,"17321-77-6",{"v":70,"d":"70.00"},199.25,{"v":70,"d":"70.00"},199.25,"http://selleckchem.com/products/Clomipramine-hydrochloride-Anafranil.html","C19H23ClN2.HCl","Hydrochloride","Anafranil","Cl.CN(C)CCCN1C2=C(CCC3=C1C=C(Cl)C=C3)C=CC=C2",5.434,0,0,4]
["S2543","Ceftiofur HCl","e2","L8000-08","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Ceftiofur HCl (U-67279A,Excenel hydrochloride) is a cephalosporin antibiotic, used to treat both Gram-positive and Gram-negative bacteria infection.",560.02,"103980-44-5",{"v":100,"d":"100.00"},178.57,"<1","N/A","http://selleckchem.com/products/Ceftiofur-hydrochloride.html","C19H17N5O7S3.HCl","Hydrochloride","U-67279A,Excenel hydrochloride","Cl.CO/N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)CSC(=O)C3=CC=CO3)C4=CSC(=N4)N",{"v":1.09,"d":"1.090"},8,2,9]
["S2549","Trospium chloride","f2","L8000-08","in 10mM DMSO","AChR","Neuronal Signaling","Trospium chloride  is a competitive muscarinic cholinergic receptor antagonist.",427.96,"10405-02-4",{"v":41,"d":"41.00"},{"v":95.8,"d":"95.80"},{"v":86,"d":"86.00"},200.95,"http://selleckchem.com/products/Trospium-chloride-Sanctura.html","C25H30NO3.Cl","quaternary-N chloride salt","N/A","[Cl-].OC(C(=O)OC1CC2CCC(C1)[N+]23CCCC3)(C4=CC=CC=C4)C5=CC=CC=C5",-0.324,2,0,5]
["S2552","Azelastine HCl","h2","L8000-08","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Azelastine HCl is a potent, second-generation, selective, histamine receptor antagonist, used in the treatment of rhinitis.",418.36,"79307-93-0",{"v":28,"d":"28.00"},66.93,{"v":35,"d":"35.00"},83.66,"http://selleckchem.com/products/azelastine.html","C22H24ClN3O.HCl","Hydrochloride","N/A","Cl.CN1CCCC(CC1)N2N=C(CC3=CC=C(Cl)C=C3)C4=CC=CC=C4C2=O",4.476,2,0,3]
["S2553","5-Aminolevulinic acid HCl","a3","L8000-08","in 10mM DMSO","Others","Others","5-Aminolevulinic Acid HCl(5-ALA hydrochloride) is an intermediate in the porphyrin synthesis pathway, used as a photosensitizing agent and a antineoplastic agent.",167.59,"5451-09-2",{"v":34,"d":"34.00"},202.88,{"v":34,"d":"34.00"},202.88,"http://selleckchem.com/products/5-Aminolevulinic-acid-hydrochloride.html","C5H9NO3.HCl","Hydrochloride","5-ALA hydrochloride","Cl.NCC(=O)CCC(O)=O",-3.318,2,1,4]
["S2554","Daphnetin","b3","L8000-08","in 10mM DMSO","EGFR,PKA,PKC","Angiogenesis","Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor, inhibits EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively, also known to exhibit anti-inflammatory and anti-oxidant activities.",178.14,"486-35-1",{"v":35,"d":"35.00"},196.47,"<1","N/A","http://selleckchem.com/products/Daphnetin.html","C9H6O4","free base","N/A","OC1=CC=C2C=CC(=O)OC2=C1O",1.415,2,2,0]
["S2555","Clarithromycin","c3","L8000-08","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Clarithromycin (A-56268) is a macrolide antibiotic and a CYP3A4 inhibitor, used to treat a number of bacterial infections.",747.95,"81103-11-9",{"v":25,"d":"25.00"},33.42,"<1","N/A","http://selleckchem.com/products/clarithromycin.html","C38H69NO13","free base","A-56268","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(CC(C)C(=O)C(C)C(O)C1(C)O)OC",{"v":2.2,"d":"2.200"},9,3,8]
["S2556","Rosiglitazone (BRL 49653)","d3","L8000-08","in 10mM DMSO","Autophagy,Ferroptosis,PPAR,TRP Channel","Metabolism","Rosiglitazone (BRL 49653) is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively. Rosiglitazone is a pure ligand of PPAR-gamma, and has no PPAR-alpha-binding action. Rosiglitazone modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis.",357.43,"122320-73-4",{"v":71,"d":"71.00"},198.64,"<1","N/A","http://selleckchem.com/products/Rosiglitazone-Avandia.html","C18H19N3O3S","Free Base","BRL 49653","CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C3=CC=CC=N3",3.268,4,1,7]
["S2559","Cortisone acetate","e3","L8000-08","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Cortisone acetate (Cortone, NSC 49420) is an acetate salt form of cortisone that is a steroid hormone and a glucocorticoid.",402.48,"50-04-4",{"v":7,"d":"7.00"},17.39,"<1","N/A","http://selleckchem.com/products/Cortisone-acetate-Cortone.html","C23H30O6","free base","Cortone,NSC 49420","CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3C(=O)CC12C",1.619,5,0,4]
["S2561","Clomifene citrate","f3","L8000-08","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Clomifene citrate (NSC 35770, Clomiphene citrate) is a selective estrogen receptor modulator, used in the treatment of ovulation induction.",598.08,"50-41-9",{"v":120,"d":"120.00"},200.64,"<1","N/A","http://selleckchem.com/products/Clomifene-citrate-Serophene.html","C26H28ClNO.C6H8O7","Citrate","NSC 35770, Clomiphene citrate","CCN(CC)CCOC1=CC=C(C=C1)C(=C(Cl)/C2=CC=CC=C2)/C3=CC=CC=C3.OC(=O)CC(O)(CC(O)=O)C(O)=O",2.129,4,0,14]
["S2564","Cloxacillin Sodium","g3","L8000-08","in 10mM DMSO","Anti-infection","Microbiology","Cloxacillin Sodium(Cloxacap,BRL 1621 sodium salt) is a sodium salt of cloxacillin that is a penicillinase-resistant, acid resistant, semi-synthetic penicillin.",475.88,"7081-44-9",{"v":55,"d":"55.00"},115.58,{"v":55,"d":"55.00"},115.58,"http://selleckchem.com/products/Cloxacillin-sodium-Cloxacap.html","C19H19ClN3NaO6S","Sodium Salt & hydrate","Cloxacap,BRL 1621 sodium salt","O.[Na+].CC1=C(C(=O)NC2C3SC(C)(C)C(N3C2=O)C([O-])=O)C(=NO1)C4=CC=CC=C4Cl",0.619,4,1,4]
["S2566","Isoprenaline (NCI-C55630) HCl","h3","L8000-08","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Isoprenaline HCl (NCI-c55630,Isoproterenol hydrochloride) is a non-selective beta-adrenergic receptor agonist, used for the treatment of bradycardia and heart block.",247.72,"51-30-9",{"v":50,"d":"50.00"},201.84,{"v":50,"d":"50.00"},201.84,"http://selleckchem.com/products/Isoprenaline-hydrochloride.html","C11H17NO3.HCl","Hydrochloride","NCI-c55630,Isoproterenol hydrochloride","Cl.CC(C)NCC(O)C1=CC=C(O)C(=C1)O",1.481,0,4,4]
["S2567","Medroxyprogesterone acetate (NSC-26386)","a4","L8000-08","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Medroxyprogesterone acetate (MPA, NSC-26386, Medroxyprogesterone 17-acetate, Farlutin) is a synthetic progestin and act as a potent progesterone receptor agonist, used to treat abnormal menstruation or irregular vaginal bleeding.",386.52,"71-58-9",{"v":12,"d":"12.00"},31.05,"<1","N/A","http://selleckchem.com/products/Medroxyprogesterone-acetate.html","C24H34O4","Free Base","MPA, NSC-26386, Medroxyprogesterone 17-acetate, Farlutin","CC1CC2C(CCC3(C)C2CCC3(OC(C)=O)C(C)=O)C4(C)CCC(=O)C=C14",3.755,4,0,3]
["S2569","Phenylephrine (NCI-C55641) HCl","b4","L8000-08","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Phenylephrine HCl (NCI-c55641,Phenylephrine hydrochloride,(R)-(-)-Phenylephrine hydrochloride, L-Phenylephrine hydrochloride) is a selective α1-adrenergic receptor agonist, used primarily as a decongestant.",203.67,"61-76-7",{"v":41,"d":"41.00"},201.31,{"v":41,"d":"41.00"},201.31,"http://selleckchem.com/products/Phenylephrine-hydrochloride.html","C9H13NO2.HCl","Hydrochloride","NCI-c55641,Phenylephrine hydrochloride,(R)-(-)-Phenylephrine hydrochloride, L-Phenylephrine hydrochloride","Cl.CNCC(O)C1=CC(=CC=C1)O",0.997,0,3,3]
["S2570","Prednisolone Acetate","c4","L8000-08","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Prednisolone Acetate (Omnipred,Prednisolone-21-acetate) is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant agent.",402.48,"52-21-1",{"v":81,"d":"81.00"},201.25,"<1","N/A","http://selleckchem.com/products/Prednisolone-acetate-Omnipred.html","C23H30O6","free base","Omnipred,Prednisolone-21-acetate","CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)C=CC4(C)C3C(O)CC12C",1.639,4,1,4]
["S2576","Xylometazoline HCl","d4","L8000-08","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM.",280.84,"1218-35-5",{"v":27,"d":"27.00"},96.14,{"v":56,"d":"56.00"},{"v":199.4,"d":"199.40"},"http://selleckchem.com/products/xylometazoline-hcl.html","C16H24N2.HCl","HCl","N/A","Cl.CC1=C(CC2=NCCN2)C(=CC(=C1)C(C)(C)C)C",3.906,1,1,3]
["S2577","Phenacetin","e4","L8000-08","in 10mM DMSO","COX","Neuronal Signaling","Phenacetin (Acetophenetidin) is a non-opioid analgesic without anti-inflammatory properties.",179.22,"62-44-2",{"v":36,"d":"36.00"},200.87,"<1","N/A","http://selleckchem.com/products/phenacetin.html","C10H13NO2","free base","Acetophenetidin","CCOC1=CC=C(NC(C)=O)C=C1",1.282,2,1,3]
["S2579","Zidovudine","f4","L8000-08","in 10mM DMSO","CRISPR/Cas9,Reverse Transcriptase","Microbiology","Zidovudine (ZDV, Azidothymidine, NSC 602670,Retrovir) is a nucleoside analogue reverse transcriptase inhibitor, used to treat HIV. It could decrease the HDR efficiency and decrease CRISPR-mediated sequence-specific genome knockin events while increaseing knockout efficiency.",267.24,"30516-87-1",{"v":53,"d":"53.00"},198.32,{"v":53,"d":"53.00"},198.32,"http://selleckchem.com/products/zidovudine-retrovir.html","C10H13N5O4","free base","Azidothymidine, NSC 602670,Retrovir","CC1=CN(C2CC(N=[N+]=[N-])C(CO)O2)C(=O)NC1=O",0.064,4,2,3]
["S2581","Quinapril HCl","g4","L8000-08","in 10mM DMSO","RAAS","Endocrinology & Hormones","Quinapril HCl (CI-906, PD-109452-2) is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM.",474.98,"82586-55-8",{"v":18,"d":"18.00"},{"v":37.9,"d":"37.90"},{"v":95,"d":"95.00"},200.01,"http://selleckchem.com/products/quinapril-hydrochloride-accupril.html","C25H30N2O5.HCl","Hydrochloride","CI-906, PD-109452-2","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=C(CC2C(O)=O)C=CC=C3",1.038,4,1,10]
["S2584","Clobetasol propionate","h4","L8000-08","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Clobetasol propionate (CGP9555, CCl 4725) is an anti-inflammatory corticosteroid used to treat various skin disorders.",466.97,"25122-46-7",{"v":93,"d":"93.00"},199.16,"<1","N/A","http://selleckchem.com/products/clobetasol-propionate.html","C25H32ClFO5","free base","CGP9555, CCl 4725","CCC(=O)OC1(C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)CCl",3.958,4,1,5]
["S2585","Brompheniramine hydrogen maleate","a5","L8000-08","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Brompheniramine hydrogen maleate(Brompheniramine maleate) is a histamine H1 receptors antagonist.",435.31,"980-71-2",{"v":87,"d":"87.00"},199.86,{"v":46,"d":"46.00"},105.67,"http://selleckchem.com/products/brompheniramine.html","C16H19BrN2.C4H4","Maleate","Brompheniramine maleate","CN(C)CCC(C1=CC=C(Br)C=C1)C2=CC=CC=N2.OC(=O)\\C=C/C(O)=O",0.784,3,0,7]
["S2586","Dimethyl Fumarate","b5","L8000-08","in 10mM DMSO","Nrf2","Immunology & Inflammation","Dimethyl fumarate (DMF,Tecfidera,BG-12) is the methyl ester of fumaric acid, used to treat people with relapsing forms of multiple sclerosis. Dimethyl fumarate is a nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator and induces upregulation of antioxidant gene expression.",144.13,"624-49-7",{"v":29,"d":"29.00"},201.21,"<1","N/A","http://selleckchem.com/products/dimethyl-Fumarate.html","C6H8O4","free base","DMF,Tecfidera,BG-12","COC(=O)\\C=C\\C(=O)OC",{"v":0.49,"d":"0.490"},4,0,4]
["S2590","Pioglitazone (AD-4833)","c5","L8000-08","in 10mM DMSO","PPAR","Metabolism","Pioglitazone (AD-4833, U 72107) is a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, used to treat diabetes; A weak activator for full-length hPPARα, but not full-length hPPARδ.",356.44,"111025-46-8",{"v":10,"d":"10.00"},28.06,"<1","N/A","https://www.selleckchem.com/products/pioglitazone.html","C19H20N2O3S","Free Base","U 72107","CCC1=CC=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)N=C1",3.907,4,1,7]
["S2593","Tolvaptan","d5","L8000-08","in 10mM DMSO","Vasopressin Receptor","GPCR & G Protein","Tolvaptan (OPC-41061) is an orally effective nonpeptide arginine vasopressin V2 receptor antagonist with IC50 of 3 nM, used to treat hyponatremia.",448.94,"150683-30-0",{"v":89,"d":"89.00"},198.24,"<1","N/A","http://selleckchem.com/products/tolvaptan-opc-41061.html","C26H25ClN2O3","free base","OPC-41061","CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(O)C4=C3C=CC(=C4)Cl)C",5.127,2,2,3]
["S2601","Gliclazide","e5","L8000-08","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Gliclazide(S1702, SE1702)  is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM.",323.41,"21187-98-4",{"v":65,"d":"65.00"},200.98,"<1","N/A","http://selleckchem.com/products/gliclazide-diamicron.html","C15H21N3O3S","free base","S1702, SE1702","CC1=CC=C(C=C1)[S](=O)(=O)NC(=O)NN2CC3CCCC3C2",1.905,3,2,3]
["S2602","Acemetacin","f5","L8000-08","in 10mM DMSO","COX","Neuronal Signaling","Acemetacin (K-708,TVX 1322) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.",415.82,"53164-05-9",{"v":83,"d":"83.00"},199.61,"<1","N/A","http://selleckchem.com/products/acemetacin-emflex.html","C21H18ClNO6","free base","K-708,TVX 1322","COC1=CC2=C(C=C1)[N](C(=C2CC(=O)OCC(O)=O)C)C(=O)C3=CC=C(Cl)C=C3",3.942,5,0,7]
["S2603","Tioxolone","g5","L8000-08","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Tioxolone(Thioxolone) is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM.",168.17,"4991-65-5",{"v":34,"d":"34.00"},202.18,"<1","N/A","http://selleckchem.com/products/tioxolone.html","C7H4O3S","free base","Thioxolone","OC1=CC=C2SC(=O)OC2=C1",2.303,2,1,0]
["S2606","Mifepristone (RU486)","a6","L8000-08","in 10mM DMSO","Apoptosis related,Autophagy,Bcl-2,Estrogen/progestogen Receptor,Glucocorticoid Receptor","Endocrinology & Hormones","Mifepristone (RU486, C-1073, RU 38486, Mifegyne) is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.",429.59,"84371-65-3",{"v":85,"d":"85.00"},197.86,"<1","N/A","http://selleckchem.com/products/Mifepristone(Mifeprex).html","C29H35NO2","free base","RU486, C-1073, RU 38486, RU-486, Mifegyne","CC#CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C(CC12C)C5=CC=C(C=C5)N(C)C",5.655,1,0,3]
["S2607","Buflomedil HCl","b6","L8000-08","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Buflomedil HCl(NSC 759291) is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease;  A nonselective alpha adrenergic receptor inhibitor.",343.85,"35543-24-9",{"v":31,"d":"31.00"},90.16,{"v":69,"d":"69.00"},200.67,"http://selleckchem.com/products/auflomedil-hcl.html","C17H25NO4.HCl","Hydrochloride","NSC 759291","Cl.COC1=CC(=C(C(=O)CCCN2CCCC2)C(=C1)OC)OC",2.939,4,0,8]
["S2610","Lonidamine (AF-1890)","c6","L8000-08","in 10mM DMSO","Carbohydrate Metabolism,Others","Metabolism","Lonidamine (AF 1890, Diclondazolic Acid, DICA) is an orally administered small molecule hexokinase inactivator.",321.16,"50264-69-2",{"v":64,"d":"64.00"},199.28,"<1","N/A","http://selleckchem.com/products/lonidamine.html","C15H10Cl2N2O2","free base","Diclondazolic Acid, DICA","OC(=O)C1=N[N](CC2=C(Cl)C=C(Cl)C=C2)C3=CC=CC=C13",{"v":4.65,"d":"4.650"},2,0,3]
["S2611","Ethisterone","d6","L8000-08","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Ethisterone(17α-Ethynyltestosterone) is a progestogen hormone being considered to treat prostate cancer.",312.45,"434-03-7",{"v":4,"d":"4.00"},{"v":12.8,"d":"12.80"},"<1","N/A","http://www.selleck.cn/products/ethisterone.html","C21H28O2","Free Base","17α-Ethynyltestosterone","CC12CCC(=O)C=C1CCC3C2CCC4(C)C3CCC4(O)C#C",4.521,1,0,0]
["S2615","Noradrenaline bitartrate monohydrate","e6","L8000-08","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Noradrenaline bitartrate monohydrate (Levophed) is a direct alpha-adrenergic receptors stimulator.",337.28,"108341-18-0",{"v":64,"d":"64.00"},189.75,{"v":64,"d":"64.00"},189.75,"http://selleckchem.com/products/noradrenaline-bitartrate-monohydrate-levophed.html","C8H11NO3.C4H6O6.H2O","bitartrate monohydrate","Levophed","O.NCC(O)C1=CC(=C(O)C=C1)O.OC(C(O)C(O)=O)C(O)=O",-4.409,2,6,5]
["S2625","Fostamatinib (R788)","f6","L8000-08","in 10mM DMSO","Syk","Angiogenesis","Fostamatinib (R788), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.",580.46,"901119-35-5",{"v":116,"d":"116.00"},199.84,"<1","N/A","http://selleckchem.com/products/R7935788-Fostamatinib.html","C23H26FN6O9P","free base","N/A","COC1=C(OC)C(=CC(=C1)NC2=NC=C(F)C(=N2)NC3=CC=C4OC(C)(C)C(=O)N(CO[P](O)(O)=O)C4=N3)OC",3.458,9,2,10]
["S2664","Clinofibrate","h6","L8000-08","in 10mM DMSO","HMG-CoA Reductase","Metabolism","Clinofibrate inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR) with IC50 of 0.47 mM, is a lipid-lowering agent used for controlling high cholesterol and triacylglyceride levels in the blood.",468.58,"30299-08-2",{"v":94,"d":"94.00"},200.61,"<1","N/A","http://selleckchem.com/products/clinofibrate.html","C28H36O6","free base","N/A","CCC(C)(OC1=CC=C(C=C1)C2(CCCCC2)C3=CC=C(OC(C)(CC)C(O)=O)C=C3)C(O)=O",6.829,4,0,10]
["S2665","Ciprofibrate","a7","L8000-08","in 10mM DMSO","PPAR","DNA Damage/DNA Repair","Ciprofibrate (Win-35833) is a peroxisome proliferator-activated receptor agonist.",289.15,"52214-84-3",{"v":58,"d":"58.00"},200.59,"<1","N/A","http://selleckchem.com/products/ciprofibrate.html","C13H14Cl2O3","free base","Win-35833","CC(C)(OC1=CC=C(C=C1)C2CC2(Cl)Cl)C(O)=O",2.954,2,0,4]
["S2673","Trametinib (GSK1120212)","b7","L8000-08","in 10mM DMSO","Apoptosis related,Autophagy,MEK","MAPK","Trametinib (GSK1120212, JTP-74057, Mekinist) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. Trametinib activates autophagy and induces apoptosis.",615.39,"871700-17-3",{"v":22,"d":"22.00"},35.75,"<1","N/A","http://selleckchem.com/products/gsk1120212-jtp-74057.html","C26H23FIN5O4","free base","JTP-74057, Mekinist","CN1C(=O)C(=C2N(C(=O)N(C3CC3)C(=O)C2=C1NC4=CC=C(I)C=C4F)C5=CC(=CC=C5)NC(C)=O)C",3.176,4,2,5]
["S2680","Ibrutinib (PCI-32765)","c7","L8000-08","in 10mM DMSO","BTK,Target Protein Ligand","Angiogenesis","Ibrutinib (PCI-32765,Imbruvica) is a potent and highly selective Brutons tyrosine kinase (Btk) inhibitor with IC50 of 0.5 nM in cell-free assays, modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc. Ibrutinib is applicable as a Btk ligand in the synthesis of a series of PROTACs including P13I.",{"v":440.5,"d":"440.50"},"936563-96-1",{"v":88,"d":"88.00"},199.77,"<1","N/A","http://selleckchem.com/products/pci-32765.html","C25H24N6O2","free base","PCI-32765,Imbruvica","NC1=C2C(=NC=N1)[N](N=C2C3=CC=C(OC4=CC=CC=C4)C=C3)C5CCCN(C5)C(=O)C=C",3.985,5,1,5]
["S2727","Dacomitinib (PF-00299804)","d7","L8000-08","in 10mM DMSO","Apoptosis related,EGFR,HER2","Protein Tyrosine Kinase","Dacomitinib (PF299804, PF299) is a potent, irreversible pan-ErbB inhibitor, mostly to EGFR with IC50 of 6 nM in a cell-free assay. Dacomitinib inhibits ERBB2 and ERBB4 with IC50 of 45.7 nM and 73.7 nM, respectively. Dacomitinib is effective against NSCLCs with EGFR or ERBB2 mutations (resistant to gefitinib) as well as those harboring the EGFR T790M mutation. Dacomitinib inhibits cell growth and induces apoptosis. Phase 2.",469.94,"1110813-31-4",{"v":19,"d":"19.00"},40.43,"<1","N/A","http://selleckchem.com/products/pf299804.html","C24H25ClFN5O2","free base","PF299804,PF299","COC1=C(NC(=O)/C=C/CN2CCCCC2)C=C3C(=NC=NC3=C1)NC4=CC(=C(F)C=C4)Cl",5.055,4,2,7]
["S2736","Fedratinib (TG101348)","e7","L8000-08","in 10mM DMSO","Apoptosis related,c-RET,FLT3,JAK","JAK/STAT","Fedratinib (SAR302503, TG101348) is a selective inhibitor of JAK2 with IC50 of 3 nM in cell-free assays, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3. Fedratinib also inhibits FMS-like tyrosine kinase 3 (FLT3) and RET (c-RET) with IC50 of 15 nM and 48 nM, respectively. Fedratinib has potential antineoplastic activity. Fedratinib inhibits proliferation and induces apoptosis. Phase 2.",524.68,"936091-26-8",{"v":100,"d":"100.00"},190.59,"<1","N/A","http://selleckchem.com/products/Fedratinib-SAR302503-TG101348.html","C27H36N6O3S","free base","SAR302503","CC1=C(NC2=CC=CC(=C2)[S](=O)(=O)NC(C)(C)C)N=C(NC3=CC=C(OCCN4CCCC4)C=C3)N=C1",5.123,5,3,11]
["S2741","Niraparib (MK-4827)","f7","L8000-08","in 10mM DMSO","Apoptosis related,PARP","DNA Damage/DNA Repair","Niraparib (MK-4827) is a selective inhibitor of PARP1/2 with IC50 of 3.8 nM/2.1 nM, with great activity in cancer cells with mutant BRCA-1 and BRCA-2. It is >330-fold selective against PARP3, V-PARP and Tank1. Niraparib can form PARP–DNA complexes resulting in DNA damage, apoptosis, and cell death. Phase 3.",320.39,"1038915-60-4",{"v":64,"d":"64.00"},199.76,"<1","N/A","http://selleckchem.com/products/mk-4827.html","C19H20N4O","Free Base","N/A","NC(=O)C1=CC=CC2=C[N](N=C12)C3=CC=C(C=C3)C4CCCNC4",2.618,2,2,3]
["S2760","Canagliflozin (JNJ 28431754)","g7","L8000-08","in 10mM DMSO","SGLT","GPCR & G Protein","Canagliflozin (TA 7284, JNJ 28431754) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM in a cell-free assay, exhibits 413-fold selectivity over hSGLT1.",444.52,"842133-18-0",{"v":88,"d":"88.00"},197.97,"<1","N/A","http://selleckchem.com/products/canagliflozin.html","C24H25FO5S","free base","TA 7284","CC1=C(CC2=CC=C(S2)C3=CC=C(F)C=C3)C=C(C=C1)C4OC(CO)C(O)C(O)C4O",3.446,1,4,5]
["S2762","Alectinib (CH5424802)","h7","L8000-08","in 10mM DMSO","ALK","Protein Tyrosine Kinase","Alectinib (CH5424802, AF-802, RG-7853) is a potent ALK inhibitor with IC50 of 1.9 nM in cell-free assays, sensitive to L1196M mutation and higher selectivity for ALK than PF-02341066, NVP-TAE684 and PHA-E429.",482.62,"1256580-46-7",{"v":6,"d":"6.00"},12.43,{"v":1,"d":"1.00"},2.07,"http://www.selleckchem.com/products/ch5424802.html","C30H34N4O2","Free Base","AF-802, RG-7853,CH5424802","CCC1=CC2=C(C=C1N3CCC(CC3)N4CCOCC4)C(C)(C)C5=C(C2=O)C6=CC=C(C=C6[NH]5)C#N",5.203,2,1,3]
["S2789","Tofacitinib (CP-690550)","a8","L8000-08","in 10mM DMSO","Apoptosis related,JAK","JAK/STAT","Tofacitinib (CP-690550,Tasocitinib) is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1. Tofacitinib inhibits the expression of antiapoptotic BCL-A1 and BCL-XL in human plasmacytoid dendritic cells (PDC) and induced PDC apoptosis.",312.37,"477600-75-2",{"v":62,"d":"62.00"},198.48,"<1","N/A","http://selleckchem.com/products/tofacitinib-cp-690550.html","C16H20N6O","free base","Tasocitinib","CC1CCN(CC1N(C)C2=C3C=C[NH]C3=NC=N2)C(=O)CC#N",1.512,3,1,3]
["S2790","Istradefylline","b8","L8000-08","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","Istradefylline (KW-6002) is a selective adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. Phase 3.",384.43,"155270-99-8",{"v":6,"d":"6.00"},15.61,"<1","N/A","http://selleckchem.com/products/istradefylline-kw-6002.html","C20H24N4O4","free base","KW-6002","CCN1C(=O)N(CC)C2=C([N](C)C(=N2)\\C=C\\C3=CC=C(OC)C(=C3)OC)C1=O",2.957,5,0,6]
["S2792","Torcetrapib","c8","L8000-08","in 10mM DMSO","CETP","Metabolism","Torcetrapib (CP-529414) is a CETP inhibitor with IC50 of 37 nM, elevates HDL-C and reduces nonHDL-C in plasma. Phase 3.",600.47,"262352-17-0",{"v":120,"d":"120.00"},199.84,"<1","N/A","http://selleckchem.com/products/torcetrapib-cp-529414.html","C26H25F9N2O4","free base","CP-529414","CCOC(=O)N1C(CC)CC(N(CC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)C(=O)OC)C3=C1C=CC(=C3)C(F)(F)F",7.345,4,0,10]
["S2797","Lonafarnib (SCH66336)","d8","L8000-08","in 10mM DMSO","Ras,Transferase","Metabolism","Lonafarnib (SCH66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM in cell-free assays, respectively. Phase 3.",638.82,"193275-84-2",{"v":127,"d":"127.00"},{"v":198.8,"d":"198.80"},"<1","N/A","http://selleckchem.com/products/lonafarnib-sch66336.html","C27H31Br2ClN4O2","free base","SCH66336","NC(=O)N1CCC(CC1)CC(=O)N2CCC(CC2)C3C4=C(CCC5=C3C(=CC(=C5)Cl)Br)C=C(Br)C=N4",5.271,3,1,3]
["S2807","Dabrafenib (GSK2118436)","e8","L8000-08","in 10mM DMSO","Raf","MAPK","Dabrafenib (GSK2118436, GSK2118436A) is a mutant BRAFV600E specific inhibitor with IC50 of 0.7 nM in cell-free assays, with 7- and 9-fold less potency against B-Raf(wt) and c-Raf, respectively.",519.56,"1195765-45-7",{"v":30,"d":"30.00"},57.74,"<1","N/A","http://selleckchem.com/products/dabrafenib-gsk2118436.html","C23H20F3N5O2S2","free base","GSK2118436A","CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(F)C(=CC=C3)N[S](=O)(=O)C4=C(F)C=CC=C4F",5.377,5,2,6]
["S2809","MPEP","f8","L8000-08","in 10mM DMSO","GluR","Neuronal Signaling","MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.",193.24,"96206-92-7",{"v":39,"d":"39.00"},201.82,"<1","N/A","http://selleckchem.com/products/mpep.html","C14H11N","free base","N/A","CC1=NC(=CC=C1)C#CC2=CC=CC=C2",3.499,1,0,2]
["S2814","Alpelisib (BYL719)","g8","L8000-08","in 10mM DMSO","PI3K","PI3K/Akt/mTOR","Alpelisib (BYL719) is a potent and selective PI3Kα inhibitor with IC50 of 5 nM in a cell-free assay, and minimal effect on PI3Kβ/γ/δ. Phase 2.",441.47,"1217486-61-7",{"v":88,"d":"88.00"},199.33,"<1","N/A","http://selleckchem.com/products/byl719.html","C19H22F3N5O2S","free base","N/A","CC1=C(SC(=N1)NC(=O)N2CCCC2C(N)=O)C3=CC(=NC=C3)C(C)(C)C(F)(F)F",2.826,4,2,5]
["S2840","Apalutamide (ARN-509)","a9","L8000-08","in 10mM DMSO","Androgen Receptor","Endocrinology & Hormones","Apalutamide (ARN-509) is a selective and competitive androgen receptor inhibitor with IC50 of 16 nM in a cell-free assay, useful for prostate cancer treatment. Phase 3.",477.43,"956104-40-8",{"v":18,"d":"18.00"},{"v":37.7,"d":"37.70"},"<1","N/A","http://selleckchem.com/products/arn-509.html","C21H15F4N5O2S","free base","N/A","CNC(=O)C1=CC=C(C=C1F)N2C(=S)N(C(=O)C23CCC3)C4=CN=C(C#N)C(=C4)C(F)(F)F",4.452,3,1,4]
["S2851","Baricitinib (INCB028050)","b9","L8000-08","in 10mM DMSO","COVID-19,JAK","JAK/STAT","Baricitinib (LY3009104, INCB028050) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM in cell-free assays, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Baricitinib is found to reduce or interrupt the passage of the virus into target cells and is used in the treatment research for COVID-19. Phase 3.",371.42,"1187594-09-7",{"v":74,"d":"74.00"},199.24,"<1","N/A","http://selleckchem.com/products/baricitinib-ly3009104.html","C16H17N7O2S","free base","LY3009104","CC[S](=O)(=O)N1CC(CC#N)(C1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4",{"v":0.36,"d":"0.360"},5,1,5]
["S2853","Carfilzomib (PR-171)","c9","L8000-08","in 10mM DMSO","Apoptosis related,Autophagy,COVID-19,Proteasome","Proteases","Carfilzomib (PR-171) is an irreversible proteasome inhibitor with IC50 of <5 nM in ANBL-6 cells, displayed preferential in vitro inhibitory potency against the ChT-L activity in the β5 subunit, but little or no effect on the PGPH and T-L activities. Carfilzomib activates prosurvival autophagy and induces cell apoptosis.",719.91,"868540-17-4",{"v":50,"d":"50.00"},69.45,"<1","N/A","http://selleckchem.com/products/carfilzomib-pr-171.html","C40H57N5O7","free base","N/A","CC(C)CC(NC(=O)C(CCC1=CC=CC=C1)NC(=O)CN2CCOCC2)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC(C)C)C(=O)C4(C)CO4",3.799,7,4,20]
["S2868","Alogliptin (SYR-322) benzoate","d9","L8000-08","in 10mM DMSO","DPP","Proteases","Alogliptin (SYR-322) benzoate is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.",461.51,"850649-62-6",{"v":68,"d":"68.00"},147.34,{"v":2,"d":"2.00"},4.33,"http://selleckchem.com/products/alogliptin-syr-322.html","C18H21N5O2.C7H6O2","benzoate","SYR-322","CN1C(=O)C=C(N2CCCC(N)C2)N(CC3=CC=CC=C3C#N)C1=O",1.271,2,1,3]
["S2874","Camostat Mesilate","e9","L8000-08","in 10mM DMSO","COVID-19,Sodium Channel","Transmembrane Transporters","Camostat (FOY-305, FOY-S980) is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.",494.52,"59721-29-8",{"v":99,"d":"99.00"},200.19,{"v":10,"d":"10.00"},20.22,"http://selleckchem.com/products/camostat-mesilate-foy-305.html","C20H22N4O5.CH4O3S","Mesilate","FOY-305, FOY-S980","CN(C)C(=O)COC(=O)CC1=CC=C(OC(=O)C2=CC=C(NC(N)=N)C=C2)C=C1.C[S](O)(=O)=O",0.969,5,2,10]
["S2875","Prucalopride","f9","L8000-08","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Prucalopride (R-93877) is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively, exhibits >290-fold selectivity against other 5-HT receptor subtypes.",367.87,"179474-81-8",{"v":60,"d":"60.00"},{"v":163.1,"d":"163.10"},"<1","N/A","http://selleckchem.com/products/prucalopride.html","C18H26ClN3O3","Free Base","R-93877","COCCCN1CCC(CC1)NC(=O)C2=CC(=C(N)C3=C2OCC3)Cl",1.056,3,2,6]
["S2883","4-Aminohippuric Acid","g9","L8000-08","in 10mM DMSO","Others","Others","4-Aminohippuric acid is a typical substrate of organic anion transport systems.",194.19,"61-78-9",{"v":39,"d":"39.00"},200.83,{"v":3,"d":"3.00"},15.45,"http://selleckchem.com/products/4-aminohippuric-acid.html","C9H10N2O3","free base","N/A","NC1=CC=C(C=C1)C(=O)NCC(O)=O",-0.227,2,2,3]
["S2884","Acesulfame Potassium","h9","L8000-08","in 10mM DMSO","Others","Others","Acesulfame potassium is a non-nutritive sweetener.",202.25,"55589-62-3",{"v":40,"d":"40.00"},197.78,{"v":40,"d":"40.00"},197.78,"http://selleckchem.com/products/acesulfame-potassium.html","C4H5NO4S.K","Potassium Salt","N/A","[KH].CC1=CC(=O)N[S](=O)(=O)O1",-0.858,2,1,0]
["S2900","Cobicistat (GS-9350)","a10","L8000-08","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Cobicistat (GS-9350) is a potent and selective inhibitor of CYP3A with IC50 of 30-285 nM.",776.02,"1004316-88-4",{"v":100,"d":"100.00"},128.86,"<1","N/A","http://selleckchem.com/products/cobicistat-gs-9350.html","C40H53N7O5S2","free base","N/A","CC(C)C1=NC(=CS1)CN(C)C(=O)NC(CCN2CCOCC2)C(=O)NC(CCC(CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)CC5=CC=CC=C5",4.765,7,3,20]
["S2902","S-Ruxolitinib (INCB018424)","b10","L8000-08","in 10mM DMSO","JAK","JAK/STAT","S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Phase 3.",306.37,"941685-37-6",{"v":61,"d":"61.00"},199.11,{"v":5,"d":"5.00"},16.32,"http://selleckchem.com/products/s-ruxolitinib.html","C17H18N6","free base","N/A","N#CCC(C1CCCC1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4",{"v":2.88,"d":"2.880"},3,1,4]
["S2907","Pirfenidone (S-7701)","c10","L8000-08","in 10mM DMSO","CCR,TGF-beta/Smad","TGF-beta/Smad","Pirfenidone (S-7701, AMR-69) is an inhibitor for TGF-β production and TGF-β stimulated collagen production, reduces production of TNF-α and IL-1β, and also has anti-fibrotic and anti-inflammatory properties. Pirfenidone attenuates chemokine (CC motif) ligand-2 (CCL2) and CCL12 production with anti-fibrotic activity. Phase 3.",185.22,"53179-13-8",{"v":37,"d":"37.00"},199.76,"<1","N/A","http://selleckchem.com/products/pirfenidone.html","C12H11NO","free base","AMR-69","CC1=CN(C(=O)C=C1)C2=CC=CC=C2",1.905,1,0,1]
["S2922","Icotinib (BPI-2009H)","d10","L8000-08","in 10mM DMSO","EGFR","Protein Tyrosine Kinase","Icotinib (BPI-2009H) is a potent and specific EGFR inhibitor with IC50 of 5 nM, including the EGFR, EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R).",391.42,"610798-31-7",{"v":78,"d":"78.00"},199.27,"<1","N/A","http://selleckchem.com/products/icotinib.html","C22H21N3O4","free base","BPI-2009H","C#CC1=CC(=CC=C1)NC2=NC=NC3=C2C=C4OCCOCCOCCOC4=C3",4.128,6,1,2]
["S3001","Clevudine","e10","L8000-08","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Clevudine(Levovir,L-FMAU) is an antiviral drug for the treatment of hepatitis B.",260.22,"163252-36-6",{"v":52,"d":"52.00"},199.83,{"v":52,"d":"52.00"},199.83,"http://selleckchem.com/products/clevudine-levovir.html","C10H13FN2O5","free base","Levovir,L-FMAU","CC1=CN(C2OC(CO)C(O)C2F)C(=O)NC1=O",-1.065,3,3,2]
["S3002","Rivaroxaban (BAY 59-7939)","f10","L8000-08","in 10mM DMSO","Factor Xa","Metabolism","Rivaroxaban (BAY 59-7939) is a direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0.7 nM in cell-free assays, respectively. It is selective for human factor Xa, for which it has >10 000-fold greater selectivity than for other biologically relevant serine proteases (IC50 >20 μM).",435.88,"366789-02-8",{"v":87,"d":"87.00"},{"v":199.6,"d":"199.60"},"<1","N/A","http://selleckchem.com/products/Rivaroxaban.html","C19H18ClN3O5S","free base","BAY 59-7939","ClC1=CC=C(S1)C(=O)NCC2CN(C(=O)O2)C3=CC=C(C=C3)N4CCOCC4=O",1.797,5,1,5]
["S3005","Paroxetine HCl","g10","L8000-08","in 10mM DMSO","Serotonin Transporter","Neuronal Signaling","Paroxetine HCl (BRL-29060A, FG-7051) is an antidepressant drug of the SSRI type.",365.83,"78246-49-8",{"v":73,"d":"73.00"},199.55,{"v":1,"d":"1.00"},2.73,"http://selleckchem.com/products/paroxetine-hcl.html","C19H20FNO3.HCl","Hydrochloride","BRL-29060A, FG-7051","Cl.FC1=CC=C(C=C1)C2CCNCC2COC3=CC4=C(OCO4)C=C3",3.611,3,1,4]
["S3008","Zaltoprofen","h10","L8000-08","in 10mM DMSO","COX","Neuronal Signaling","Zaltoprofen(CN100,Soleton) is an inhibitor of COX-1 and COX-2 for treatment of arthritis.",298.36,"74711-43-6",{"v":60,"d":"60.00"},{"v":201.1,"d":"201.10"},"<1","N/A","http://selleckchem.com/products/zaltoprofen.html","C17H14O3S","free base","CN100,Soleton","CC(C(O)=O)C1=CC2=C(SC3=CC=CC=C3C(=O)C2)C=C1",3.684,2,0,2]
["S3012","Pazopanib","a11","L8000-08","in 10mM DMSO","Autophagy,Cathepsin B,c-Kit,CSF-1R,Cysteine Protease,FGFR,PDGFR,VEGFR","Protein Tyrosine Kinase","Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms/CSF1R with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively. Pazopanib induces cathepsin B activation and autophagy.",437.52,"444731-52-6",{"v":87,"d":"87.00"},198.85,"<1","N/A","http://selleckchem.com/products/pazopanib.html","C21H23N7O2S","Free Base","GW786034","C[N]1N=C2C=C(C=CC2=C1C)N(C)C3=NC(=NC=C3)NC4=CC=C(C)C(=C4)[S](N)(=O)=O",3.741,5,2,5]
["S3015","Amoxicillin","b11","L8000-08","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Amoxicillin (Amoxycillin) is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms.",{"v":365.4,"d":"365.40"},"26787-78-0",{"v":73,"d":"73.00"},199.78,"<1","N/A","http://selleckchem.com/products/amoxicillin-amoxycillin.html","C16H19N3O5S","Free Base","Amoxycillin","CC1(C)SC2C(NC(=O)C(N)C3=CC=C(O)C=C3)C(=O)N2C1C(O)=O",-2.539,3,3,4]
["S3017","Aspirin (NSC 27223)","c11","L8000-08","in 10mM DMSO","Autophagy,COX,Mitophagy","Metabolism","Aspirin (NSC 27223, Acetylsalicylic acid, ASA) is a salicylate, and irreversible COX1 and COX2 inhibitor, used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. Aspirin induces autophagy and stimulates mitophagy.",180.16,"50-78-2",{"v":36,"d":"36.00"},199.82,"<1","N/A","http://selleckchem.com/products/aspirin-acetylsalicylic-acid.html","C9H8O4","free base","Acetylsalicylic acid, ASA","CC(=O)OC1=C(C=CC=C1)C(O)=O",1.227,3,0,3]
["S3018","Niflumic acid","d11","L8000-08","in 10mM DMSO","COX,GABA Receptor","Neuronal Signaling","Niflumic acid(Nifluril) is an inhibitor of cyclooxygenase-2 used for joint and muscular pain.",282.22,"4394-00-7",{"v":56,"d":"56.00"},198.43,"<1","N/A","http://selleckchem.com/products/niflumic-acid.html","C13H9F3N2O2","free base","Nifluril","OC(=O)C1=CC=CN=C1NC2=CC=CC(=C2)C(F)(F)F",{"v":3.34,"d":"3.340"},2,1,4]
["S3019","Ciclopirox ethanolamine","e11","L8000-08","in 10mM DMSO","ATPase,Fungal","Transmembrane Transporters","Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296,Ciclopiroxolamine) is a broad-spectrum antifungal agent working as an iron chelator.",268.35,"41621-49-2",{"v":6,"d":"6.00"},22.36,"<1","N/A","http://selleckchem.com/products/ciclopirox-ethanolamine.html","C12H17NO2.C2H7NO","Ethanolamine","Ciclopirox olamine, HOE 296,Ciclopiroxolamine","CC1=CC(=O)N(O)C(=C1)C2CCCCC2.NCCO",1.302,1,2,2]
["S3021","Rimonabant (SR141716)","f11","L8000-08","in 10mM DMSO","Acyltransferase,Bacterial,Cannabinoid Receptor,MmpL3,Transferase","GPCR & G Protein","Rimonabant (SR141716) is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Rimonabant is also a dual inhibitor of acyl CoA:cholesterol acyltransferases(ACAT) 1 and 2 and inhibits mycobacterial MmpL3.",463.79,"168273-06-1",{"v":25,"d":"25.00"},{"v":53.9,"d":"53.90"},"<1","N/A","http://selleckchem.com/products/rimonabant-sr141716.html","C22H21Cl3N4O","free base","SR141716","CC1=C([N](N=C1C(=O)NN2CCCCC2)C3=CC=C(Cl)C=C3Cl)C4=CC=C(Cl)C=C4",6.613,2,1,4]
["S3022","Cabazitaxel (XRP6258)","g11","L8000-08","in 10mM DMSO","Autophagy,Microtubule Associated","Cytoskeletal Signaling","Cabazitaxel (RPR-116258A, XRP6258, TXD 258, Taxoid XRP6258) is a semi-synthetic derivative of a natural taxoid that kills cancer cells by inhibiting cell division and growth. Cabazitaxel exerts its effects by inhibiting microtubule growth and assembly, processes that are essential for cells to divide. Cabazitaxel induces autophagy via the PI3K/Akt/mTOR pathway.",835.93,"183133-96-2",{"v":100,"d":"100.00"},119.63,"<1","N/A","http://selleckchem.com/products/cabazitaxel-jevtana.html","C45H57NO14","free base","RPR-116258A, TXD 258, Taxoid XRP6258","COC1CC2OCC2(OC(C)=O)C3C(OC(=O)C4=CC=CC=C4)C5(O)CC(OC(=O)C(O)C(NC(=O)OC(C)(C)C)C6=CC=CC=C6)C(=C(C(OC)C(=O)C13C)C5(C)C)C",3.403,12,2,15]
["S3023","Bufexamac","h11","L8000-08","in 10mM DMSO","COX,IFN","Neuronal Signaling","Bufexamac(Bufexamic acid) is a COX inhibitor for IFN-α release with EC50 of 8.9 μM.",223.27,"2438-72-4",{"v":45,"d":"45.00"},201.55,"<1","N/A","http://selleckchem.com/products/bufexamac.html","C12H17NO3","free base","Bufexamic acid","CCCCOC1=CC=C(CC(=O)NO)C=C1",2.191,2,1,6]
["S3024","Lamotrigine","a2","L8000-09","in 10mM DMSO","5-HT Receptor,Sodium Channel","Transmembrane Transporters","Lamotrigine (BW-430C,LTG) is a novel anticonvulsant drug for inhibition of 5-HT with IC50 of 240 μM and 474 μM in human platelets and rat brain synaptosomes, and also is a sodium channel blocker.",256.09,"84057-84-1",{"v":10,"d":"10.00"},39.05,"<1","N/A","http://selleckchem.com/products/lamotrigine.html","C9H7Cl2N5","free base","BW-430C,LTG","NC1=NC(=C(N=N1)C2=CC=CC(=C2Cl)Cl)N",2.426,3,2,1]
["S3027","Fenoprofen calcium hydrate","b2","L8000-09","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Fenoprofen calcium hydrate(Fenoprofen calcium salt dihydrate,Feprona dihydrate,Progesic dihydrate) is a non-steroidal anti-inflammatory drug (NSAID).",558.63,"71720-56-4, 53746-45-5",{"v":48,"d":"48.00"},85.92,"<1","N/A","http://selleckchem.com/products/fenoprofen-calcium-hydrate.html","C30H30CaO8","Calcium dihydrate salt","Fenoprofen calcium salt dihydrate,Feprona dihydrate,Progesic dihydrate","O.O.CC(C(=O)O[Ca]OC(=O)C(C)C1=CC=CC(=C1)OC2=CC=CC=C2)C3=CC=CC(=C3)OC4=CC=CC=C4",6.802,6,0,12]
["S3030","Niclosamide (BAY2353)","c2","L8000-09","in 10mM DMSO","Autophagy,STAT","JAK/STAT","Niclosamide (BAY2353, Niclocide, NSC 178296) can inhibit DNA replication and inhibit STAT3 with IC50 of 0.7 μM in a cell-free assay. Niclosamide selectively inhibited the phosphorylation of STAT3 and had no obvious inhibition against the activation of other homologues (e.g., STAT1 and STAT5).",327.12,"50-65-7",{"v":8,"d":"8.00"},24.46,"<1","N/A","http://www.selleck.cn/products/niclosamide-niclocide.html","C13H8Cl2N2O4","Free Base","Niclocide, NSC 178296","OC1=CC=C(Cl)C=C1C(=O)NC2=C(Cl)C=C(C=C2)[N+]([O-])=O",3.595,1,2,3]
["S3035","Daunorubicin (RP 13057) HCl","d2","L8000-09","in 10mM DMSO","ADC Cytotoxin,Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,COVID-19,DNA/RNA Synthesis,Topoisomerase","DNA Damage/DNA Repair","Daunorubicin HCl (Daunomycin, RP 13057, Rubidomycin) inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM in a cell-free assay. Daunorubicin is a topoisomerase II inhibitor that induces apoptosis.",563.98,"23541-50-6",{"v":100,"d":"100.00"},177.31,{"v":100,"d":"100.00"},177.31,"http://selleckchem.com/products/daunorubicin-hcl-daunomycin-hcl.html","C27H29NO10.HCl","Hydrochloride","Daunomycin HCl, Rubidomycin HCl","Cl.COC1=C2C(=O)C3=C(C(=C4CC(O)(CC(OC5CC(N)C(O)C(C)O5)C4=C3O)C(C)=O)O)C(=O)C2=CC=C1",{"v":1.01,"d":"1.010"},6,4,4]
["S3036","Pravastatin sodium","e2","L8000-09","in 10mM DMSO","HMG-CoA Reductase","Metabolism","Pravastatin sodium (CS-514) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.",446.51,"81131-70-6",{"v":89,"d":"89.00"},199.32,{"v":89,"d":"89.00"},199.32,"http://selleckchem.com/products/pravastatin-pravachol.html","C23H35O7.Na","sodium","CS-514 Sodium","[Na+].CCC(C)C(=O)OC1CC(O)C=C2C=CC(C)C(CCC(O)CC(O)CC([O-])=O)C12",0.682,2,3,11]
["S3037","Bepotastine Besilate","f2","L8000-09","in 10mM DMSO","COVID-19,Histamine Receptor","Neuronal Signaling","Bepotastine Besilate (TAU 284) is a non-sedating, selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7.",547.06,"190786-44-8",{"v":109,"d":"109.00"},199.25,"<1","N/A","http://selleckchem.com/products/bepotastine-besilate.html","C21H25ClN2O3.C6H6O3S","Besilate salt","TAU 284","OC(=O)CCCN1CCC(CC1)OC(C2=CC=C(Cl)C=C2)C3=NC=CC=C3.O[S](=O)(=O)C4=CC=CC=C4",1.371,3,0,9]
["S3038","Fosaprepitant dimeglumine salt","g2","L8000-09","in 10mM DMSO","Neurokinin Receptor","Neuronal Signaling","Fosaprepitant dimeglumine salt (MK-0517) is a water-soluble phosphoryl prodrug for Aprepitant which is a NK1 antagonist.",1004.83,"265121-04-8",{"v":201,"d":"201.00"},200.03,{"v":135,"d":"135.00"},134.35,"http://selleckchem.com/products/fosaprepitant.html","C23H22F7N4O6P.2C7H17NO5","dimeglumine salt","MK-0517","CNCC(O)C(O)C(O)C(O)CO.CNCC(O)C(O)C(O)C(O)CO.CC(OC1OCCN(CC2=NN(C(=O)N2)[P](O)(O)=O)C1C3=CC=C(F)C=C3)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F",-1.235,4,13,21]
["S3043","Rofecoxib","h2","L8000-09","in 10mM DMSO","COX","Neuronal Signaling","Rofecoxib (MK-0966) is a COX-2 inhibitor with IC50 of 18 nM.",314.36,"162011-90-7",{"v":63,"d":"63.00"},200.41,"<1","N/A","http://selleckchem.com/products/rofecoxib-vioxx.html","C17H14O4S","free base","MK-0966","C[S](=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3",2.871,4,0,3]
["S3046","Azilsartan","a3","L8000-09","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Azilsartan (TAK-536) is an angiotensin II type 1 (AT1) receptor antagonist with IC50 of 2.6 nM.",456.45,"147403-03-0",{"v":91,"d":"91.00"},199.36,"<1","N/A","http://selleckchem.com/products/azilsartan-tak-536.html","C25H20N4O5","free base","TAK-536","CCOC1=NC2=CC=CC(=C2[N]1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)ON5)C(O)=O",4.662,6,1,7]
["S3047","Otilonium Bromide","b3","L8000-09","in 10mM DMSO","AChR","Neuronal Signaling","Otilonium bromide is an antimuscarinic.",563.57,"26095-59-0",{"v":113,"d":"113.00"},200.51,{"v":113,"d":"113.00"},200.51,"http://selleckchem.com/products/otilonium-bromide.html","C29H43BrN2O4","quaternary-N bromide salt","N/A","[Br-].CCCCCCCCOC1=CC=CC=C1C(=O)NC2=CC=C(C=C2)C(=O)OCC[N+](C)(CC)CC",{"v":2.67,"d":"2.670"},4,1,17]
["S3052","Rupatadine Fumarate","c3","L8000-09","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Rupatadine is an inhibitor of PAFR and histamine (H1) receptor with Ki of 550 nM and 102 nM, respectively.",532.03,"182349-12-8",{"v":9,"d":"9.00"},16.92,"<1","N/A","http://selleckchem.com/products/rupatadine-fumarate.html","C26H26ClN3.C4H4O4","Fumarate","N/A","CC1=CN=CC(=C1)CN2CCC(CC2)=C3C4=CC=C(Cl)C=C4CCC5=CC=CN=C35.OC(=O)\\C=C\\C(O)=O",2.672,4,0,4]
["S3054","Alverine Citrate","d3","L8000-09","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Alverine citrate (NSC 35459) is a drug used for functional gastrointestinal disorders. Alverine citrate is a 5-HT1A receptor antagonist, with an IC50 of 101 nM.",473.56,"5560-59-8",{"v":95,"d":"95.00"},200.61,"<1","N/A","http://selleckchem.com/products/alverine-citrate.html","C20H27N.C6H8O7","Citrate","NSC 35459","CCN(CCCC1=CC=CC=C1)CCCC2=CC=CC=C2.OC(=O)CC(O)(CC(O)=O)C(O)=O",1.037,3,0,14]
["S3057","Azilsartan Medoxomil","e3","L8000-09","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Azilsartan Medoxomil (TAK-491) is a potent angiotensin II type 1 (AT1) receptor antagonist, inhibits the RAAS, with an IC50 of 2.6 nM, exhibits >10,000-fold selectivity over AT2.",568.53,"863031-21-4",{"v":114,"d":"114.00"},200.52,"<1","N/A","http://selleckchem.com/products/azilsartan-medoxomil-tak-491.html","C30H24N4O8","free base","TAK-491","CCOC1=NC2=CC=CC(=C2[N]1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)ON5)C(=O)OCC6=C(C)OC(=O)O6",{"v":5.27,"d":"5.270"},10,1,10]
["S3067","Chlorhexidine 2HCl","f3","L8000-09","in 10mM DMSO","Anti-infection","Microbiology","Chlorhexidine hydrochloride (NSC-185) is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.",578.37,"3697-42-5",{"v":100,"d":"100.00"},{"v":172.9,"d":"172.90"},"<1","N/A","http://selleckchem.com/products/chlorhexidine-hcl.html","C22H30Cl2N10.2HCl","HCl","NSC-185","Cl.Cl.ClC1=CC=C(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC2=CC=C(Cl)C=C2)C=C1",5.137,0,6,17]
["S3078","Beclomethasone dipropionate","h3","L8000-09","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Beclomethasone dipropionate(Beclovent,Beconase,Vancenase)  is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.",521.04,"5534-09-8",{"v":104,"d":"104.00"},{"v":199.6,"d":"199.60"},"<1","N/A","http://selleckchem.com/products/beclomethasone-dipropionate.html","C28H37ClO7","free base","Beclometasone dipropionate,Beclovent,Beconase,Vancenase","CCC(=O)OCC(=O)C1(OC(=O)CC)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(Cl)C(O)CC12C",4.064,6,1,8]
["S3079","Atovaquone","a4","L8000-09","in 10mM DMSO","COVID-19,Fungal,Parasite","Microbiology","Atovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.",366.84,"95233-18-4",{"v":5,"d":"5.00"},13.63,"<1","N/A","http://selleckchem.com/products/atovaquone-atavaquone.html","C22H19ClO3","free base","Atavaquone","OC1=C(C2CCC(CC2)C3=CC=C(Cl)C=C3)C(=O)C4=C(C=CC=C4)C1=O",5.319,2,1,2]
["S3080","Etravirine (TMC125)","b4","L8000-09","in 10mM DMSO","Reverse Transcriptase","Microbiology","Etravirine (TMC125, R-165335) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.",435.28,"269055-15-4",{"v":42,"d":"42.00"},96.49,"<1","N/A","http://selleckchem.com/products/etravirine-tmc125.html","C20H15BrN6O","free base","R-165335","CC1=CC(=CC(=C1OC2=C(Br)C(=NC(=N2)NC3=CC=C(C=C3)C#N)N)C)C#N",5.492,3,2,4]
["S3081","Ulipristal Acetate (CDB 2914)","c4","L8000-09","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Ulipristal acetate (CDB-2914, HRP 2000, RU 44675) is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.",475.62,"126784-99-4",{"v":83,"d":"83.00"},191.43,"<1","N/A","http://selleckchem.com/products/ulipristal.html","C30H37NO4","free base","HRP 2000, RU 44675","CN(C)C1=CC=C(C=C1)C2CC3(C)C(CCC3(OC(C)=O)C(C)=O)C4CCC5=CC(=O)CCC5=C24",4.309,2,0,3]
["S3083","Indacaterol Maleate","d4","L8000-09","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Indacaterol (QAB149) is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor.",508.56,"753498-25-8",{"v":102,"d":"102.00"},200.57,"<1","N/A","http://selleckchem.com/products/indacaterol-maleate.html","C24H28N2O3.C4H4O4","Maleate","QAB149","CCC1=CC2=C(CC(C2)NCC(O)C3=CC=C(O)C4=C3C=CC(=O)N4)C=C1CC.OC(=O)\\C=C/C(O)=O",1.264,3,4,8]
["S3100","2-Thiouracil","e4","L8000-09","in 10mM DMSO","Hydroxylase","Neuronal Signaling","2-Thiouracil(Deracil,Thiouracil) is a thiolated uracil derivative that is a known antihyperthyroid agent.",128.15,"141-90-2",{"v":26,"d":"26.00"},202.89,"<1","N/A","http://selleckchem.com/products/2-thiouracil.html","C4H4N2OS","free base","Deracil,Thiouracil","O=C1NC(=S)NC=C1",0.081,1,2,0]
["S3104","Moguisteine","f4","L8000-09","in 10mM DMSO","Others","Others","Moguisteine(BBR-2173) is a novel peripheral non-narcotic antitussive drug.",339.41,"119637-67-1",{"v":68,"d":"68.00"},200.35,"<1","N/A","http://selleckchem.com/products/moguisteine.html","C16H21NO5S","free base","BBR-2173","CCOC(=O)CC(=O)N1CCSC1COC2=CC=CC=C2OC",2.212,5,0,8]
["S3105","Nadifloxacin","g4","L8000-09","in 10mM DMSO","Antibiotics","Microbiology","Nadifloxacin (OPC-7251) is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris.",360.38,"124858-35-1",{"v":20,"d":"20.00"},{"v":55.5,"d":"55.50"},"<1","N/A","http://selleckchem.com/products/nadifloxacin.html","C19H21FN2O4","free base","OPC-7251","CC1CCC2=C3N1C=C(C(O)=O)C(=O)C3=CC(=C2N4CCC(O)CC4)F",1.865,2,1,2]
["S3116","Sulfathiazole","h4","L8000-09","in 10mM DMSO","Anti-infection","Microbiology","Sulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug.",255.32,"72-14-0",{"v":51,"d":"51.00"},199.75,"<1","N/A","http://selleckchem.com/products/sulfathiazole.html","C9H9N3O2S2","free base","N/A","NC1=CC=C(C=C1)[S](=O)(=O)NC2=NC=CS2",0.568,3,2,3]
["S3117","Oxybutynin hydrochloride","a5","L8000-09","in 10mM DMSO","AChR","Neuronal Signaling","Oxybutynin(MJ4309-1) is an anticholinergic medication used to relieve urinary and bladder difficulties.",393.95,"1508-65-2",{"v":79,"d":"79.00"},200.53,{"v":4,"d":"4.00"},10.15,"https://www.selleckchem.com/products/oxybutynin-hydrochloride.html","C22H31NO3.HCl","hydrochloride","MJ4309-1","Cl.CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)C2=CC=CC=C2",5.028,2,0,10]
["S3120","Doxepin HCl","b5","L8000-09","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Doxepin is a tricyclic antidepressant formulated as a mixture of E-(trans) and Z-(cis) stereoisomers. It inhibits CYP2D6 activity in vivo.",315.84,"1229-29-4",{"v":63,"d":"63.00"},199.47,{"v":63,"d":"63.00"},199.47,"http://selleckchem.com/products/doxepin-hydrochloride-sinequan.html","C19H21NO.HCl","hydrochloride","N/A","Cl.CN(C)CC\\C=C1/C2=CC=CC=C2COC3=C1C=CC=C3",{"v":4.29,"d":"4.290"},1,0,3]
["S3124","Dexamethasone Acetate","c5","L8000-09","in 10mM DMSO","Complement System,COVID-19,IL Receptor","Immunology & Inflammation","Dexamethasone (NSC 39471,Dexamethasone 21-acetate) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator  that has anti-inflammatory and immunosuppressant effects.",{"v":434.5,"d":"434.50"},"1177-87-3",{"v":87,"d":"87.00"},200.23,"<1","N/A","http://selleckchem.com/products/dexamethasone-acetate.html","C24H31FO6","free base","NSC 39471,Dexamethasone 21-acetate","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)COC(C)=O",2.087,4,1,4]
["S3129","Trimethoprim","d5","L8000-09","in 10mM DMSO","Antibiotics,Bacterial,DHFR","Microbiology","Trimethoprim (BW 56-72, NIH 204, NSC-106568) is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.",290.32,"738-70-5",{"v":58,"d":"58.00"},199.78,"<1","N/A","http://selleckchem.com/products/trimethoprim.html","C14H18N4O3","free base","BW 56-72, NIH 204, NSC-106568","COC1=C(OC)C(=CC(=C1)CC2=CN=C(N)N=C2N)OC",1.543,5,2,5]
["S3132","Sulfamerazine","e5","L8000-09","in 10mM DMSO","Bacterial","Microbiology","Sulfamerazine (RP 2632,sulphamerazine) is a sulfonamide antibacterial.",{"v":264.3,"d":"264.30"},"127-79-7",{"v":53,"d":"53.00"},200.53,"<1","N/A","http://selleckchem.com/products/sulfamerazine.html","C11H12N4O2S","free base","RP 2632,sulphamerazine","CC1=NC(=NC=C1)N[S](=O)(=O)C2=CC=C(N)C=C2",0.595,4,2,3]
["S3137","Sodium salicylate","f5","L8000-09","in 10mM DMSO","NF-κB","NF-κB","Sodium salicylate(2-Hydroxybenzoic acid Sodium salt,Salicylic acid Sodium salt) is used in medicine as an analgesic and antipyretic.",161.11,"54-21-7",{"v":32,"d":"32.00"},198.62,{"v":32,"d":"32.00"},198.62,"http://selleckchem.com/products/sodium-salicylate.html","C7H6O3.Na","sodium salt","2-Hydroxybenzoic acid Sodium salt,Salicylic acid Sodium salt","[NaH].OC(=O)C1=CC=CC=C1O",1.217,1,1,1]
["S3138","Methylthiouracil","g5","L8000-09","in 10mM DMSO","ERK,Interleukins,NF-κB,TNF-alpha","NF-κB","Methylthiouracil (NSC-193526, NSC-9378,MTU) is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.",142.18,"56-04-2",{"v":28,"d":"28.00"},196.93,"<1","N/A","http://selleckchem.com/products/methylthiouracil.html","C5H6N2OS","free base","NSC-193526, NSC-9378,MTU","CC1=CC(=O)NC(=S)N1",0.595,1,2,0]
["S3144","Darifenacin HBr","h5","L8000-09","in 10mM DMSO","AChR","Neuronal Signaling","Darifenacin HBr (UK-88525) is a selective M3 muscarinic receptor antagonist with pKi of 8.9.",507.46,"133099-07-7",{"v":100,"d":"100.00"},197.06,"<1","N/A","http://selleckchem.com/products/darifenacin-hydrobromide.html","C28H30N2O2.HBr","HBr","UK-88525","Br.NC(=O)C(C1CCN(CCC2=CC=C3OCCC3=C2)C1)(C4=CC=CC=C4)C5=CC=CC=C5",5.048,2,1,7]
["S3149","Estradiol valerate","a6","L8000-09","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estradiol(E2V) is a synthetic ester used to treat menopausal symptoms and hormone deficiencies.",{"v":356.5,"d":"356.50"},"979-32-8",{"v":71,"d":"71.00"},199.16,"<1","N/A","http://selleckchem.com/products/estradiol-valerate.html","C23H32O3","free base","E2V","CCCCC(=O)OC1CCC2C3CCC4=CC(=CC=C4C3CCC12C)O",5.796,2,1,5]
["S3151","Gliquidone","b6","L8000-09","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Gliquidone (Glurenorm,AR-DF 26) is an ATP-sensitive K+ channel antagonist with IC50 of 27.2 nM.",527.63,"33342-05-1",{"v":105,"d":"105.00"},{"v":199,"d":"199.00"},"<1","N/A","http://selleckchem.com/products/gliquidone.html","C27H33N3O6S","free base","Glurenorm,AR-DF 26","COC1=CC2=C(C=C1)C(C)(C)C(=O)N(CCC3=CC=C(C=C3)[S](=O)(=O)NC(=O)NC4CCCCC4)C2=O",4.214,6,2,7]
["S3160","Ethynodiol diacetate","c6","L8000-09","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Ethynodiol diacetate (8080 CB,Ethynodiol acetate) is one of the first synthetic progestogens used in contraceptive pills.",384.51,"297-76-7",{"v":77,"d":"77.00"},200.25,{"v":77,"d":"77.00"},200.25,"http://selleckchem.com/products/ethynodiol-diacetate.html","C24H32O4","free base","8080 CB,Ethynodiol acetate","CC(=O)OC1CCC2C3CCC4(C)C(CCC4(OC(C)=O)C#C)C3CCC2=C1",4.973,4,0,4]
["S3162","Tylosin tartrate","d6","L8000-09","in 10mM DMSO","Antibiotics,Antibiotics for Mammalian Cell Culture","Microbiology","Tylosin tartrate is a macrolide antibiotic approved for the control of mycoplasmosis in poultry.",1066.19,"74610-55-2",{"v":300,"d":"300.00"},281.38,{"v":200,"d":"200.00"},187.58,"http://selleckchem.com/products/tylosin-tartrate.html","C46H77NO17.C4H6O6","Tartrate","N/A","CCC1OC(=O)CC(O)C(C)C(OC2OC(C)C(OC3CC(C)(O)C(O)C(C)O3)C(C2O)N(C)C)C(CC=O)CC(C)C(=O)\\C=C\\C(=C\\C1COC4OC(C)C(O)C(OC)C4OC)C.OC(C(O)C(O)=O)C(O)=O",-2.989,14,6,16]
["S3167","Altrenogest","e6","L8000-09","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Altrenogest (A35957, RU2267,R2267) is a progestogen structurally related to veterinary steroid trenbolone.",310.43,"850-52-2",{"v":62,"d":"62.00"},199.72,"<1","N/A","http://selleckchem.com/products/altrenogest.html","C21H26O2","free base","A35957, RU2267,R2267","CC12C=CC3=C4CCC(=O)C=C4CCC3C1CCC2(O)CC=C",3.561,1,0,2]
["S3170","Ampicillin sodium","f6","L8000-09","in 10mM DMSO","Antibiotics,Antibiotics for Mammalian Cell Culture,Selection Antibiotics for Transfected Cell","Microbiology","Ampicillin(D-(-)-α-Aminobenzylpenicillin sodium salt) is a beta-lactam antibiotic that is part of the aminopenicillin family.",371.39,"69-52-3",{"v":37,"d":"37.00"},99.63,{"v":74,"d":"74.00"},199.25,"http://selleckchem.com/products/ampicillin-sodium.html","C16H18N3NaO4S","Sodium","D-(-)-α-Aminobenzylpenicillin sodium salt","[Na+].CC1(C)SC2C(NC(=O)C(N)C3=CC=CC=C3)C(=O)N2C1C([O-])=O",-1.292,2,2,4]
["S3172","Anagrelide HCl","g6","L8000-09","in 10mM DMSO","PDE","Metabolism","Anagrelide (BL-4162A,BMY 26538-01) is a drug used for the treatment of essential thrombocytosis.",292.55,"58579-51-4",{"v":14,"d":"14.00"},47.86,"<1","N/A","http://selleckchem.com/products/anagrelide-hydrochloride.html","C10H7Cl2N3O.HCl","Hydrochloride","BL-4162A,BMY 26538-01","Cl.ClC1=CC=C2NC3=NC(=O)CN3CC2=C1Cl",2.347,2,1,0]
["S3173","Antipyrine","h6","L8000-09","in 10mM DMSO","COX","Neuronal Signaling","Antipyrine (Phenazone,Phenazon) is an analgesic and antipyretic agent; selective COX-3 inhibitor.",188.23,"60-80-0",{"v":38,"d":"38.00"},201.88,{"v":38,"d":"38.00"},201.88,"http://selleckchem.com/products/antipyrine.html","C11H12N2O","free base","Phenazone,Phenazon","CN1N(C(=O)C=C1C)C2=CC=CC=C2",1.218,1,0,1]
["S3175","Atomoxetine HCl","a7","L8000-09","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Atomoxetine (LY 139603) is a selective norepinephrine (NE) transporter inhibitor with Ki of 5 nM, with 15- and 290-fold lower affinity for human 5-HT and DA transporters.",291.82,"82248-59-7",{"v":58,"d":"58.00"},198.75,{"v":2,"d":"2.00"},6.85,"http://selleckchem.com/products/atomoxetine-hydrochloride.html","C17H21NO.HCl","HCl","LY 139603 HCl","Cl.CNCCC(OC1=CC=CC=C1C)C2=CC=CC=C2",3.959,1,1,6]
["S3176","Betahistine 2HCl","b7","L8000-09","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Betahistine (PT-9) is a histamine H3 receptor inhibitor with IC50 of 1.9 μM.",209.12,"5579-84-0",{"v":38,"d":"38.00"},181.71,{"v":38,"d":"38.00"},181.71,"http://selleckchem.com/products/betahistine-dihydrochloride.html","C8H12N2.2HCl","2HCl","PT-9","Cl.Cl.CNCCC1=NC=CC=C1",1.444,1,1,3]
["S3178","Brinzolamide","c7","L8000-09","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Brinzolamide (AL-4862) is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM.",383.51,"138890-62-7",{"v":77,"d":"77.00"},200.78,"<1","N/A","http://selleckchem.com/products/brinzolamide.html","C12H21N3O5S3","free base","AL-4862","CCNC1CN(CCCOC)[S](=O)(=O)C2=C1C=C(S2)[S](N)(=O)=O",-0.772,5,2,7]
["S3180","Eletriptan HBr","d7","L8000-09","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Eletriptan (UK-116044) is a selective 5-HT1B and 5-HT1D receptor agonist with Ki of 0.92 nM and 3.14 nM, respectively.",463.43,"177834-92-3",{"v":93,"d":"93.00"},200.68,"<1","N/A","http://selleckchem.com/products/eletriptan-hydrobromide.html","C22H26N2O2S.HBr","HBr","UK-116044","Br.CN1CCCC1CC2=C[NH]C3=C2C=C(CC[S](=O)(=O)C4=CC=CC=C4)C=C3",4.929,2,1,6]
["S3181","Flumequine","e7","L8000-09","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Flumequine(R-802) is a synthetic chemotherapeutic antibiotic, inhibiting topoisomerase II with IC50 of 15 μM.",261.25,"42835-25-6",{"v":3,"d":"3.00"},11.48,"<1","N/A","http://selleckchem.com/products/flumequine.html","C14H12FNO3","free base","R-802","CC1CCC2=C3N1C=C(C(O)=O)C(=O)C3=CC(=C2)F",{"v":2.27,"d":"2.270"},2,0,1]
["S3183","Amitriptyline HCl","f7","L8000-09","in 10mM DMSO","5-HT Receptor,Histamine Receptor,Serotonin Transporter","Neuronal Signaling","Amitriptyline HCl is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline HCl also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. Amitriptyline is a tricyclic antidepressant (TCA).",313.86,"549-18-8",{"v":63,"d":"63.00"},200.73,{"v":15,"d":"15.00"},47.79,"http://selleckchem.com/products/amitriptyline-hydrochloride.html","C20H23N.HCl","HCl","N/A","Cl.CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C13",5.154,0,0,3]
["S3185","Adrenalone HCl","g7","L8000-09","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic, mainly acts on alpha-1 adrenergic receptors.",217.65,"62-13-5",{"v":44,"d":"44.00"},202.16,{"v":44,"d":"44.00"},202.16,"http://selleckchem.com/products/adrenalone-hcl.html","C9H11NO3.HCl","HCl","N/A","Cl.CNCC(=O)C1=CC(=C(O)C=C1)O",0.938,1,3,3]
["S3186","Azatadine dimaleate","h7","L8000-09","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Azatadine (SCH10649,Azatadine Maleate) is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively.",522.55,"3978-86-7",{"v":105,"d":"105.00"},200.94,{"v":105,"d":"105.00"},200.94,"http://selleckchem.com/products/azatadine-dimaleate.html","C20H22N2.2C4H4O4","Dimaleate","SCH10649,Azatadine Maleate","CN1CCC(CC1)=C2C3=CC=CC=C3CCC4=CC=CN=C24.OC(=O)\\C=C/C(O)=O.OC(=O)\\C=C/C(O)=O",1.128,5,0,4]
["S3195","Azlocillin sodium salt","b8","L8000-09","in 10mM DMSO","Bacterial","Microbiology","Azlocillin is an acylampicillin with a broad spectrum against bacteria.",484.48,"37091-65-9",{"v":97,"d":"97.00"},200.21,{"v":97,"d":"97.00"},200.21,"http://selleckchem.com/products/azlocillin-sodium-salt.html","C20H23N5O6S.Na","Sodium Salt","N/A","[NaH].CC1(C)SC2C(NC(=O)C(NC(=O)N3CCNC3=O)C4=CC=CC=C4)C(=O)N2C1C(O)=O",0.004,5,3,5]
["S3200","Triflusal","c8","L8000-09","in 10mM DMSO","COX","Immunology & Inflammation","Triflusal (UR1501) irreversibly inhibits the production of thromboxane-B2 in platelets by acetylating cycloxygenase-1.",248.16,"322-79-2",{"v":50,"d":"50.00"},201.48,"<1","N/A","http://selleckchem.com/products/triflusal.html","C10H7F3O4","free base","UR1501","CC(=O)OC1=CC(=CC=C1C(O)=O)C(F)(F)F",2.169,3,0,4]
["S3201","Trifluoperazine 2HCl","d8","L8000-09","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Trifluoperazine (NSC-17474, RP-7623, SKF-5019) 2HCl is a dopamine D2 receptor inhibitor with IC50 of 1.1 nM. Trifluoperazine also inhibits calmodulin (CaM).",480.42,"440-17-5",{"v":88,"d":"88.00"},183.17,{"v":96,"d":"96.00"},199.83,"http://selleckchem.com/products/trifluoperazine-dihydrochloride.html","C21H24F3N3S.2HCl","2HCl","SKF5019","Cl.Cl.CN1CCN(CCCN2C3=C(SC4=CC=C(C=C24)C(F)(F)F)C=CC=C3)CC1",5.739,0,0,5]
["S3212","Moclobemide (Ro 111163)","f8","L8000-09","in 10mM DMSO","MAO","Metabolism","Moclobemide is a MAO-A (5-HT) inhibitor with IC50 of 6.1 μM.",268.74,"71320-77-9",{"v":53,"d":"53.00"},197.22,"<1","N/A","http://selleckchem.com/products/moclobemide.html","C13H17ClN2O2","free base","N/A","ClC1=CC=C(C=C1)C(=O)NCCN2CCOCC2",1.528,2,1,4]
["S3604","Triptolide (PG490)","g8","L8000-09","in 10mM DMSO","ADC Cytotoxin,Apoptosis related,HSP (HSP90),MDM2/MDMX,NF-κB","NF-κB","Triptolide (PG490, NSC 163062) is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It functions as a NF-κB inhibitor with dual actions by disruption of p65/CBP interaction and by reduction of p65 protein. Triptolide (PG490) abrogates the transactivation function of heat shock transcription factor 1 (HSF1). Triptolide inhibits MDM2 and induces apoptosis through a p53-independent pathway.",{"v":360.4,"d":"360.40"},"38748-32-2",{"v":72,"d":"72.00"},199.78,"<1","N/A","http://selleckchem.com/products/triptolide.html","C20H24O6","free base","NSC 163062","CC(C)C12OC1C3OC34C5(C)CCC6=C(COC6=O)C5CC7OC47C2O",0.872,5,1,1]
["S3606","Fangchinoline","h8","L8000-09","in 10mM DMSO","Reverse Transcriptase","Microbiology","Fangchinoline, a bisbenzylisoquinoline alkaloid, is a novel HIV-1 inhibitor with pain-relieving, blood pressure-depressing, and antibiotic activities.",608.72,"33889-68-8",{"v":100,"d":"100.00"},164.28,"<1","N/A","http://selleckchem.com/products/r-s-fangchinoline.html","C37H40N2O6","free base","N/A","COC1=C2OC3=CC=C(CC4N(C)CCC5=C4C=C(OC6=C(O)C(=CC7=C6C(CC(=C2)C=C1)N(C)CC7)OC)C(=C5)OC)C=C3",6.992,5,1,3]
["S3609","Berbamine dihydrochloride","a9","L8000-09","in 10mM DMSO","Bcr-Abl,CaMK,NF-κB","Angiogenesis","Berbamine (BA, BBM) dihydrochloride, a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan), is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF-κB. Berbamine (BA, BBM) dihydrochloride induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca²⁺/calmodulin-dependent protein kinase II (CaMKII).",681.65,"6078-17-7",{"v":100,"d":"100.00"},{"v":146.7,"d":"146.70"},{"v":100,"d":"100.00"},{"v":146.7,"d":"146.70"},"http://selleckchem.com/products/berbamine-dihydrochloride.html","C37H40N2O6.2HCl","dihydrochloride","BA, BBM","Cl.Cl.COC1=CC2=C3C=C1OC4=C(OC)C(=CC5=C4C(CC6=CC(=C(O)C=C6)OC7=CC=C(CC3N(C)CC2)C=C7)N(C)CC5)OC",7.756,5,1,3]
["S3611","(+)-Fangchinoline","b9","L8000-09","in 10mM DMSO","Others","Others","Fangchinoline ((+)-Limacine, Tetrandrine B, Hanfangichin B) is a phytochemical that has been shown to elicit anti-cancer effects in prostate and breast cancer cell lines via inducing G1 cell cycle arrest. It has also been shown to possess neuroprotective activity.",608.72,"436-77-1",{"v":40,"d":"40.00"},65.71,"<1","N/A","http://selleckchem.com/products/s-s-fangchinoline.html","C37H40N2O6","free base","(+)-Limacine, Tetrandrine B, Hanfangichin B","COC1=C2OC3=CC=C(CC4N(C)CCC5=C4C=C(OC6=C7C(CC(=C2)C=C1)N(C)CCC7=CC(=C6O)OC)C(=C5)OC)C=C3",6.992,5,1,3]
["S3612","Rosmarinic acid","c9","L8000-09","in 10mM DMSO","Complement System,IκB/IKK","NF-κB","Rosmarinic acid (RA, Rosemary acid) is a naturally occurring hydroxylated compound. It has the ability to block complement fixation, inhibit lipoxygenase and cyclooxygenase activity and inhibit the expression of CCL11 and CCR3 by suppressing the IKK-β activity in NF-κB activation signaling.",360.31,"20283-92-5",{"v":72,"d":"72.00"},199.83,{"v":24,"d":"24.00"},66.61,"http://selleckchem.com/products/rosmarinic-acid.html","C18H16O8","free base","Rosemary acid","OC(=O)C(CC1=CC=C(O)C(=C1)O)OC(=O)\\C=C\\C2=CC=C(O)C(=C2)O",2.706,3,4,7]
["S3615","Dehydrocostus Lactone","d9","L8000-09","in 10mM DMSO","IκB/IKK","NF-κB","Dehydrocostus lactone (DHE), a natural sesquiterpene lactone, inhibits IKKβ activity, IκBα phosphorylation and degradation, coactivators p300 recruitments and p50/p65 NF-κB nuclear translocation, and their DNA binding activity on COX-2 promoter. It has anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.",{"v":230.3,"d":"230.30"},"477-43-0",{"v":46,"d":"46.00"},199.74,"<1","N/A","http://selleckchem.com/products/dehydrocostus-lactone.html","C15H18O2","free base","N/A","C=C1CCC2C(OC(=O)C2=C)C3C1CCC3=C",3.282,2,0,0]
["S3616","Asiaticoside","e9","L8000-09","in 10mM DMSO","ROS","Immunology & Inflammation","Asiaticoside (Ba 2742, BRN0078195, CCRIS8995, NSC166062, Emdecassol,Madecassol), the major active principle of Centella asiatica, prevents ultraviolet A-dependent photoaging by suppressing ultraviolet A-induced reactive oxygen species production. It also decreases DNA binding by MITF.",959.12,"16830-15-2",{"v":100,"d":"100.00"},104.26,"<1","N/A","http://selleckchem.com/products/asiaticoside.html","C48H78O19","free base","Ba 2742, BRN0078195, CCRIS8995, NSC166062, Emdecassol,Madecassol","CC1CCC2(CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(CO)C5CCC34C)C2C1C)C(=O)OC6OC(COC7OC(CO)C(OC8OC(C)C(O)C(O)C8O)C(O)C7O)C(O)C(O)C6O",-0.101,7,12,10]
["S3621","Pazufloxacin mesylate","f9","L8000-09","in 10mM DMSO","Bacterial","Microbiology","Pazufloxacin Mesylate (T-3762, Pazucross), also known as Pazucross and T-3762, is a quinolone antibacterial agent used for the intravenous therapy of several infections.",414.41,"163680-77-1",{"v":82,"d":"82.00"},197.87,{"v":82,"d":"82.00"},197.87,"http://selleckchem.com/products/pazufloxacin-mesylate.html","C16H15FN2O4.CH4O3S","methanesulfonate","T-3762, Pazucross","CC1COC2=C(C(=CC3=C2N1C=C(C(O)=O)C3=O)F)C4(N)CC4.C[S](O)(=O)=O",-1.899,3,1,2]
["S3622","Diammonium Glycyrrhizinate","g9","L8000-09","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Diammonium glycyrrhizinate (DG), a traditional Chinese medicine (TCM), is extracted and purified from liquorices (Radix glycyrrhizae). It is known for its anti-inflammatory effects, resistance to biologic oxidation and membranous protection. DG is able to reduce inflammatory injury via suppression of NF‑κB, TNF‑α and intercellular adhesion molecule 1.",856.99,"79165-06-3",{"v":100,"d":"100.00"},116.69,{"v":100,"d":"100.00"},116.69,"http://selleckchem.com/products/diammonium-glycyrrhizinate.html","C42H62O16.2H3N","ammonium salt","N/A","N.N.CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O)OC6OC(C(O)C(O)C6OC7OC(C(O)C(O)C7O)C(O)=O)C(O)=O",-4.247,8,5,7]
["S3625","Tyramine","h9","L8000-09","in 10mM DMSO","TAAR","GPCR & G Protein","Tyramine (4-hydroxyphenethylamine, para-tyramine, mydrial, uteramin) is a naturally occurring trace amine derived from the amino acid tyrosine and acts as a catecholamine releasing agent.",137.18,"51-67-2",{"v":27,"d":"27.00"},196.82,"<1","N/A","http://selleckchem.com/products/tyramine.html","C8H11NO","free base","4-hydroxyphenethylamine, para-tyramine, mydrial, uteramin","NCCC1=CC=C(O)C=C1",1.015,0,2,2]
["S3627","Tryptamine","a10","L8000-09","in 10mM DMSO","TAAR","GPCR & G Protein","Tryptamine is a monoamine alkaloid and may play a role as a neuromodulator or neurotransmitter. It is an agonist of hTAAR1. It acts as a non-selective serotonin receptor agonist and serotonin-norepinephrine-dopamine releasing agent (SNDRA).",160.22,"61-54-1",{"v":32,"d":"32.00"},199.73,"<1","N/A","http://selleckchem.com/products/tryptamine.html","C10H12N2","free base","N/A","NCCC1=C[NH]C2=CC=CC=C12",{"v":1.55,"d":"1.550"},0,2,2]
["S3635","Medroxyprogesterone","b10","L8000-09","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Medroxyprogesterone (MP) is a synthetic pregnane steroid and a derivative of progesterone. It is a potent progesterone receptor agonist.",344.49,"520-85-4",{"v":68,"d":"68.00"},197.39,"<1","N/A","http://selleckchem.com/products/medroxyprogesterone.html","C22H32O3","free base","MP","CC1CC2C(CCC3(C)C2CCC3(O)C(C)=O)C4(C)CCC(=O)C=C14",3.376,2,0,1]
["S3639","Tacrine hydrochloride hydrate","c10","L8000-09","in 10mM DMSO","AChR,HNMT","Neuronal Signaling","Tacrine (Tetrahydroaminacrine, Tetrahydroaminoacridine) is a centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. It also acts as a histamine N-methyltransferase inhibitor.","198.26(free bases)","206658-92-6",{"v":50,"d":"50.00"},252.19,{"v":50,"d":"50.00"},252.19,"http://selleckchem.com/products/tacrine-hydrochloride-hydrate.html","C13H14N2.xHCl.xH2O","hydrochloride hydrate","Tacrine, Tetrahydroaminacrine, Tetrahydroaminoacridine","NC1=C2C=CC=CC2=NC3=C1CCCC3",4.258,1,1,0]
["S3641","Osalmid","d10","L8000-09","in 10mM DMSO","DNA/RNA Synthesis,RNR","DNA Damage/DNA Repair","Osalmid suppresses ribonucleotide reductase (RNR) activity in a concentration-dependent manner, with a 50% RR activity-inhibitory concentration (IC50) of 8.23 μM.",229.23,"526-18-1",{"v":45,"d":"45.00"},196.31,"<1","N/A","http://selleckchem.com/products/osalmid.html","C13H11NO3","free base","N/A","OC1=CC=C(NC(=O)C2=C(O)C=CC=C2)C=C1",{"v":2.13,"d":"2.130"},1,3,2]
["S3643","Amitraz","e10","L8000-09","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Amitraz (NSC 324552) is a triazapentadiene, an α2 adrenergic agonist and a member of the amidine chemical family. It is a non-systemic acaricide and insecticide.",293.41,"33089-61-1",{"v":58,"d":"58.00"},197.68,"<1","N/A","http://selleckchem.com/products/amitraz.html","C19H23N3","free base","NSC 324552","CN(C=NC1=CC=C(C)C=C1C)C=NC2=CC=C(C)C=C2C",4.825,2,0,4]
["S3647","Mafenide Acetate","f10","L8000-09","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Mafenide Acetate is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.",246.28,"13009-99-9",{"v":49,"d":"49.00"},198.96,{"v":49,"d":"49.00"},198.96,"http://selleckchem.com/products/mafenide-acetate.html","C7H10N2O2S.C2H4O2","acetate","N/A","CC(O)=O.NCC1=CC=C(C=C1)[S](N)(=O)=O",-3.043,3,2,2]
["S3648","Amlexanox (AA-673)","g10","L8000-09","in 10mM DMSO","Immunology & Inflammation related,IκB/IKK,TBK1","Immunology & Inflammation","Amlexanox (AA-673, CHX-3673, Amoxanox) is an anti-inflammatory antiallergic immunomodulator and also an inhibitor of the protein kinases TBK1 and IKK-ε.",298.29,"68302-57-8",{"v":59,"d":"59.00"},197.79,"<1","N/A","http://selleckchem.com/products/amlexanox.html","C16H14N2O4","free base","CHX-3673, Amoxanox","CC(C)C1=CC2=C(OC3=NC(=C(C=C3C2=O)C(O)=O)N)C=C1",2.969,4,1,2]
["S3654","Tauroursodeoxycholic Acid (TUDCA)","h10","L8000-09","in 10mM DMSO","Mitochondrial Metabolism","Neuronal Signaling","Tauroursodeoxycholic acid (TUDCA) is the taurine conjugate of ursodeoxycholic acid (UDCA) and acts as a mitochondrial stabilizer and anti-apoptotic agent in several models of neurodegenerative diseases, including AD, Parkinson's diseases (PD), and Huntington's diseases (HD).",{"v":499.7,"d":"499.70"},"14605-22-2",{"v":99,"d":"99.00"},198.12,{"v":30,"d":"30.00"},60.04,"http://selleckchem.com/products/tauroursodeoxycholic-acid.html","C26H45NO6S","free base","N/A","CC(CCC(=O)NCC[S](O)(=O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C",2.997,1,3,7]
["S3655","Cefepime Dihydrochloride Monohydrate","a11","L8000-09","in 10mM DMSO","Bacterial","Microbiology","Cefepime is a cephalosporin antibacterial drug used to treat pneumonia, urinary tract, skin, and intra-abdominal infections.",{"v":571.5,"d":"571.50"},"123171-59-5",{"v":100,"d":"100.00"},174.98,{"v":1,"d":"1.00"},1.75,"http://selleckchem.com/products/cefepime-dihydrochloride-monohydrate.html","C19H25N6O5S2.HCl.Cl.H2O","dihydrochloride hydrate","N/A","O.Cl.Cl.CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)C[N+]3(C)CCCC3)C4=CSC(=N4)N",-2.421,5,2,7]
["S3656","Piribedil","b11","L8000-09","in 10mM DMSO","Adrenergic Receptor,Dopamine Receptor","Neuronal Signaling","Piribedil (Trivastal, Trivastan) is a relatively selective dopamine (D2/D3) agonist with moderate antidepressant activity. It also has α2-adrenergic (α2A/α2C) antagonist properties.",298.34,"3605-01-4",{"v":59,"d":"59.00"},197.76,"<1","N/A","http://selleckchem.com/products/piribedil.html","C16H18N4O2","free base","Trivastal, Trivastan","C1OC2=CC=C(CN3CCN(CC3)C4=NC=CC=N4)C=C2O1",2.043,4,0,3]
["S3657","Promestriene","c11","L8000-09","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Promestriene (3-propyl ethyl, 17B-methyl estradiol) is a synthetic estrogen analog that has been reported to significantly improve the symptoms of vaginal atrophy caused by estrogen deprivation in topical application.",328.49,"39219-28-8",{"v":65,"d":"65.00"},197.88,{"v":3,"d":"3.00"},9.13,"http://selleckchem.com/products/promestriene.html","C22H32O2","free base","3-propyl ethyl, 17B-methyl estradiol","CCCOC1=CC2=C(C=C1)C3CCC4(C)C(CCC4C3CC2)OC",5.344,2,0,4]
["S3659","Fludrocortisone acetate","d11","L8000-09","in 10mM DMSO","Others","Others","Fludrocortisone (9α-fluorocortisol) is a synthetic pregnane steroid and a halogenated derivative of cortisol. It is used to treat adrenogenital syndrome, postural hypotension, and adrenal insufficiency.",422.49,"514-36-3",{"v":84,"d":"84.00"},198.82,"<1","N/A","http://selleckchem.com/products/fludrocortisone-acetate.html","C23H31FO6","free base","9α-fluorocortisol acetate","CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3(F)C(O)CC12C",1.791,4,1,4]
["S3666","Ilaprazole","e11","L8000-09","in 10mM DMSO","ATPase,Proton Pump","Transmembrane Transporters","Ilaprazole (IY-81149) is a new proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. It inhibits H+/K+-ATPase with an IC50 of 6.0 μM.",366.44,"172152-36-2",{"v":73,"d":"73.00"},199.21,"<1","N/A","http://selleckchem.com/products/ilaprazole.html","C19H18N4O2S","free base","IY-81149","COC1=CC=NC(=C1C)C[S](=O)C2=NC3=C([NH]2)C=C(C=C3)[N]4C=CC=C4",3.311,4,1,5]
["S3668","Thymopentin","f11","L8000-09","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Thymopentin (TP5) has immuno-regulatory activities. The immuno-regulatory actions of thymopentin on peripheral T cells are mediated by intracellular cyclic GMP elevations in contrast to the intracellular cyclic AMP elevations induced in precursor T cells that trigger their further differentiation to T cells.",679.77,"69558-55-0",{"v":100,"d":"100.00"},147.11,{"v":100,"d":"100.00"},147.11,"http://selleckchem.com/products/thymopentin.html","C30H49N9O9","free base","TP5","CC(C)C(NC(=O)C(CC(O)=O)NC(=O)C(CCCCN)NC(=O)C(N)CCCNC(N)=N)C(=O)NC(CC1=CC=C(O)C=C1)C(O)=O",-6.675,6,9,23]
["S3669","Carmustine","g11","L8000-09","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Carmustine (bis-chloroethylnitrosourea, BCNU, BiCNU) is a cell-cycle phase nonspecific alkylating antineoplastic agent and used in the treatment of brain tumors and various other malignant neoplasms.",214.05,"154-93-8","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/carmustine.html","C5H9Cl2N3O2","free base","bis-chloroethylnitrosourea, BCNU, BiCNU","ClCCNC(=O)N(CCCl)N=O",1.201,2,1,5]
["S3671","Quinestrol","h11","L8000-09","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Quinestrol (Ethinylestradiol 3-cyclopentyl ether, EE2CPE, W-3566) is a synthetic, steroidal estrogen which is used in hormone replacement therapy and occasionally to treat breast cancer and prostate cancer.",364.52,"152-43-2",{"v":72,"d":"72.00"},197.52,"<1","N/A","http://selleckchem.com/products/quinestrol.html","C25H32O2","free base","Ethinylestradiol 3-cyclopentyl ether, EE2CPE, W-3566","CC12CCC3C(CCC4=C3C=CC(=C4)OC5CCCC5)C1CCC2(O)C#C",6.514,1,0,2]
["S3672","Cefonicid sodium","a2","L8000-10","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Cefonicid sodium (Monocid) is a cephalosporin antibiotic. It interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism.",586.53,"61270-78-8",{"v":100,"d":"100.00"},170.49,{"v":100,"d":"100.00"},170.49,"http://selleckchem.com/products/cefonicid-sodium.html","C18H16N6O8S3.2Na","disodium salt","Monocid sodium","[Na+].[Na+].OC(C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)CSC3=NN=N[N]3C[S]([O-])(=O)=O)C4=CC=CC=C4",-4.327,5,2,9]
["S3675","Umbelliferone","b2","L8000-10","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Umbelliferone (7-hydroxycoumarin, hydrangine, skimmetine, beta-umbelliferone) is a 7-hydroxycoumarin that is a pharmacologically active agent. It is a fluorescing compound used as a sunscreen agent and shows good inhibitions of DPPH, hydroxyl, superoxide anion and ABTS radicals with anti-inflammatory, anti-hyperglycaemic, molluscicidal and anti-tumor activities.",162.14,"93-35-6",{"v":32,"d":"32.00"},197.36,"<1","N/A","http://selleckchem.com/products/umbelliferone.html","C9H6O3","free base","7-hydroxycoumarin, hydrangine, skimmetine, beta-umbelliferone","OC1=CC2=C(C=C1)C=CC(=O)O2",1.657,2,1,0]
["S3676","Carbendazim","c2","L8000-10","in 10mM DMSO","Fungal","Microbiology","Carbendazim (Mercarzole, Carbendazole) is a broad-spectrum systemic antimycotic and can be used to control a broad range of diseases on field crops, fruits, and vegetables, including sclerotinia rot of canola, wheat head blight, peanut leaf spot, and SB on rice. Its mode of action is to inhibit the formation of mitotic microtubules in of fungi.",191.19,"10605-21-7",{"v":17,"d":"17.00"},88.92,"<1","N/A","http://selleckchem.com/products/carbendazim.html","C9H9N3O2","free base","Mercarzole, Carbendazole","COC(=O)NC1=NC2=C([NH]1)C=CC=C2",{"v":1.65,"d":"1.650"},3,2,2]
["S3677","Cinnamic acid","d2","L8000-10","in 10mM DMSO","Others","Others","Cinnamic acid (Benzenepropenoic acid, Isocinnamic acid, trans-Cinnamic acid, Phenylacrylic acid), a naturally occurring aromatic fatty acid of low toxicity, induces cytostasis and a reversal of malignant properties of human tumor cells in vitro.",148.16,"140-10-3",{"v":29,"d":"29.00"},195.73,"<1","N/A","http://selleckchem.com/products/cinnamic-acid.html","C9H8O2","free base","trans-Cinnamic acid, Phenylacrylic acid, Cinnamylic acid, 3-Phenylacrylic acid|(E)-Cinnamic acid, Benzenepropenoic acid, Isocinnamic acid","OC(=O)/C=C/C1=CC=CC=C1",1.927,1,0,2]
["S3681","Vitamin E Acetate","e2","L8000-10","in 10mM DMSO","Vitamin","Metabolism","Vitamin E Acetate (Tocopherol) is the stable form of Vitamin E most often used in cosmetic formulations for its skin care benefits. It protects the cells against free radicals and prevents the peroxidation of body fats as an in-vivo antioxidant., Vitamin E Acetate (Tocopherol) is the stable form of Vitamin E most often used in cosmetic formulations for its skin care benefits. It protects the cells against free radicals and prevents the peroxidation of body fats as an in-vivo antioxidant. ,",472.74,"58-95-7","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/vitamin-e-acetate.html","C31H52O3","free base","Tocopherol acetate","CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=C(C)C(=C(C)C(=C2O1)C)OC(C)=O",{"v":10.45,"d":"10.450"},3,0,14]
["S3684","Methacholine chloride","f2","L8000-10","in 10mM DMSO","AChR","Neuronal Signaling","Methacholine (Mecholyl, Acetyl-β-methylcholine) is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic nervous system but has little effects on the nicotinic receptors.",195.69,"62-51-1",{"v":39,"d":"39.00"},199.29,{"v":39,"d":"39.00"},199.29,"http://selleckchem.com/products/methacholine-chloride.html","C8H18NO2.Cl","chloride","Mecholyl chloride, Acetyl-β-methylcholine chloride","[Cl-].CC(C[N+](C)(C)C)OC(C)=O",-3.492,2,0,4]
["S3687","Urea","h2","L8000-10","in 10mM DMSO","Others","Metabolism","Urea (Carbonyldiamide, Ureophil) is a highly soluble organic compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.",60.06,"57-13-6",{"v":12,"d":"12.00"},{"v":199.8,"d":"199.80"},{"v":12,"d":"12.00"},{"v":199.8,"d":"199.80"},"http://selleckchem.com/products/urea.html","CH4N2O","free base","Carbonyldiamide, Ureophil","NC(N)=O",-1.043,1,2,0]
["S3690","Pargyline hydrochloride","a3","L8000-10","in 10mM DMSO","MAO","Metabolism","Pargyline is an irreversible inhibitor of monoamine oxidase (MAO)-B with Ki values of 13 and 0.5 μM for time-dependent inhibition of the activity of MAO-A and -B, respectivey.",195.69,"306-07-0",{"v":39,"d":"39.00"},199.29,{"v":39,"d":"39.00"},199.29,"http://selleckchem.com/products/pargyline-hydrochloride.html","C11H13N.HCl","hydrochloride","Pargylamine hydrochloride","Cl.CN(CC#C)CC1=CC=CC=C1",3.477,0,0,3]
["S3692","N-Ethylmaleimide (NEM)","b3","L8000-10","in 10mM DMSO","Cysteine Protease,DUB","Proteases","N-Ethylmaleimide (NEM) is an organic compound that is derived from maleic acid. It is an irreversible inhibitor of all cysteine peptidases, with alkylation occurring at the active site thiol group. N-Ethylmaleimide (NEM) inactivates endogenous deubiquitinating enzymes (DUBs). N-Ethylmaleimide (NEM) specifically inhibits phosphate transport in mitochondria.",125.13,"128-53-0",{"v":25,"d":"25.00"},199.79,{"v":25,"d":"25.00"},199.79,"http://selleckchem.com/products/n-ethylmaleimide-nem.html","C6H7NO2","free base","N/A","CCN1C(=O)C=CC1=O",{"v":0.16,"d":"0.160"},2,0,1]
["S3694","Glucosamine hydrochloride","c3","L8000-10","in 10mM DMSO","Others","Immunology & Inflammation","Glucosamine (2-Amino-2-deoxy-glucose, Chitosamine) is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, also presents in the shells of shellfish, animal bones, bone marrow, and fungi. Glucosamine is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.",215.63,"66-84-2",{"v":4,"d":"4.00"},18.55,{"v":43,"d":"43.00"},199.42,"http://selleckchem.com/products/glucosamine-hydrochloride.html","C6H13NO5.HCl","hydrochloride","2-Amino-2-deoxy-glucose HCl, Chitosamine HCl","Cl.NC1C(O)OC(CO)C(O)C1O",-2.422,1,4,1]
["S3697","Mafenide hydrochloride","d3","L8000-10","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Mafenide is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.",222.69,"138-37-4",{"v":44,"d":"44.00"},197.58,{"v":44,"d":"44.00"},197.58,"http://selleckchem.com/products/mafenide-hydrochloride.html","C7H10N2O2S.HCl","hydrochloride","4-Aminomethylbenzenesulfonamide hydrochloride","Cl.NCC1=CC=C(C=C1)[S](N)(=O)=O",0.023,2,2,2]
["S3698","Nortriptyline hydrochloride","e3","L8000-10","in 10mM DMSO","Autophagy","Autophagy","Nortriptyline hydrochloride (Desitriptyline, ELF-101, EN-7048, Desmethylamitriptyline) is the hydrochloride salt form of nortriptyline, a tricyclic antidepressant agent used for short-term treatment of various forms of depression.",299.84,"894-71-3",{"v":59,"d":"59.00"},196.77,{"v":59,"d":"59.00"},196.77,"http://selleckchem.com/products/nortriptyline-hydrochloride.html","C19H21N.HCl","hydrochloride","Desitriptyline HCl, ELF-101 hydrochloride, EN-7048 hydrochloride, Desmethylamitriptyline hydrochloride","Cl.CNCCC=C1C2=C(CCC3=C1C=CC=C3)C=CC=C2",4.618,0,1,3]
["S3701","Benactyzine hydrochloride","f3","L8000-10","in 10mM DMSO","AChR","Neuronal Signaling","Benactyzine hydrochloride is a centrally acting muscarinic antagonist. It is used as an antidepressant in the treatment of depression and associated anxiety.",363.88,"57-37-4",{"v":72,"d":"72.00"},197.87,{"v":72,"d":"72.00"},197.87,"http://selleckchem.com/products/benactyzine-hydrochloride.html","C20H25NO3.HCl","hydrochloride","N/A","Cl.CCN(CC)CCOC(=O)C(O)(C1=CC=CC=C1)C2=CC=CC=C2",3.832,2,0,9]
["S3707","Ethopabate","g3","L8000-10","in 10mM DMSO","Parasite","Microbiology","Ethopabate (ETP, Ethyl pabate) is a coccidiostat that is frequently used to prevent and treat coccidiosis in chickens.",237.25,"59-06-3",{"v":47,"d":"47.00"},{"v":198.1,"d":"198.10"},"<1","N/A","http://selleckchem.com/products/ethopabate.html","C12H15NO4","free base","Ethyl pabate","CCOC1=CC(=CC=C1C(=O)OC)NC(C)=O",1.138,4,1,5]
["S3711","Carbasalate Calcium","h3","L8000-10","in 10mM DMSO","Anti-infection","Microbiology","Carbasalate calcium (Iromin, Alcacyl, Omegin, Rheomin, Solupsan) is an analgesic, antipyretic, and anti-inflammatory drug as well as a platelet aggregation inhibitor.",458.43,"5749-67-7",{"v":11,"d":"11.00"},23.99,{"v":91,"d":"91.00"},{"v":198.5,"d":"198.50"},"http://selleckchem.com/products/carbasalate-calcium.html","C18H14O8.CH4N2O.Ca","calcium salt","Iromin, Alcacyl, Omegin, Rheomin, Solupsan","CC(=O)OC1=C(C=CC=C1)C(=O)O[Ca]OC(=O)C2=C(OC(C)=O)C=CC=C2.NC(N)=O",1.594,9,2,10]
["S3714","Lifitegrast","a4","L8000-10","in 10mM DMSO","Integrin","Cytoskeletal Signaling","Lifitegrast (SAR1118,SHP-606) is a novel small molecule integrin antagonist that inhibits a specific T cell-mediated inflammatory pathway involved in the pathogenesis of DED.",615.48,"1025967-78-5",{"v":100,"d":"100.00"},162.47,"<1","N/A","http://selleckchem.com/products/lifitegrast.html","C29H24Cl2N2O7S","free base","SAR1118,SHP-606","C[S](=O)(=O)C1=CC=CC(=C1)CC(NC(=O)C2=C(Cl)C=C3CN(CCC3=C2Cl)C(=O)C4=CC=C5C=COC5=C4)C(O)=O",{"v":4.79,"d":"4.790"},6,1,7]
["S3724","Velpatasvir","d4","L8000-10","in 10mM DMSO","COVID-19,HCV Protease","Proteases","Velpatasvir (GS-5816,VEL) is a second-generation NS5A inhibitor that inhibits hepatitis C viral replication through acting on the crucial \"membranous web\" that facilitates RNA replication.",{"v":883,"d":"883.00"},"1377049-84-7",{"v":100,"d":"100.00"},113.25,{"v":100,"d":"100.00"},113.25,"http://selleckchem.com/products/velpatasvir.html","C49H54N8O8","free base","GS-5816,VEL","COCC1CC(N(C1)C(=O)C(NC(=O)OC)C2=CC=CC=C2)C3=NC=C([NH]3)C4=CC=C5C(=C4)COC6=C5C=C7C=CC8=C(N=C([NH]8)C9CCC(C)N9C(=O)C(NC(=O)OC)C(C)C)C7=C6",5.789,10,4,13]
["S3731","Tipiracil hydrochloride","e4","L8000-10","in 10mM DMSO","Phosphorylase,Thymidylate Synthase","Metabolism","Tipiracil (MA-1) is an inhibitor of thymidine phosphorylase, the enzyme that degrades trifluridine into trifluorothymidine. Its combination with trifluridine increases the bioavailability of trifluridine.",279.12,"183204-72-0",{"v":8,"d":"8.00"},28.66,{"v":55,"d":"55.00"},197.05,"http://selleckchem.com/products/tipiracil-hydrochloride.html","C9H11ClN4O2.HCl","hydrochloride","MA-1 hydrochloride","Cl.ClC1=C(CN2CCCC2=N)NC(=O)NC1=O",-0.388,2,2,2]
["S3732","Avibactam sodium","f4","L8000-10","in 10mM DMSO","β-lactamase","Microbiology","Avibactam (AVE-1330A, NXL104) is a covalent, reversible, non-β-lactam β-lactamase inhibitor with IC50 values of 8, 80, and 38 nM for TEM-1, P99, and KPC-2 β-lactamases, respectively.",287.23,"1192491-61-4",{"v":57,"d":"57.00"},198.45,{"v":57,"d":"57.00"},198.45,"http://selleckchem.com/products/avibactam-sodium.html","C7H10N3O6.Na","sodium salt","AVE-1330A, NXL104","[Na+].NC(=O)C1CCC2CN1C(=O)N2O[S]([O-])(=O)=O",-3.785,3,1,3]
["S3739","Calcipotriene","g4","L8000-10","in 10mM DMSO","Vitamin","Metabolism","Calcipotriene (Calcipotriol, MC903) is a synthetic derivative of calcitriol, a form of vitamin D. It can induce differentiation and suppresses proliferation of keratinocytes, reversing abnormal keratinocyte changes in psoriasis, and lead to normalization of epidermal growth.  Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.",{"v":412.6,"d":"412.60"},"112965-21-6",{"v":82,"d":"82.00"},198.74,"<1","N/A","http://selleckchem.com/products/calcipotriene.html","C27H40O3","free base","Calcipotriol, MC903","CC(\\C=C\\C(O)C1CC1)C2CCC3/C(CCCC23C)=C/C=C\\4CC(O)CC(O)C4=C",4.679,0,3,5]
["S3742","Cholic acid","h4","L8000-10","in 10mM DMSO","Others","Metabolism","Cholic acid is a naturally occurring bile acid that is insoluble in water and is used to treat patients with genetic deficiencies in the synthesis of bile acids.",408.57,"81-25-4",{"v":81,"d":"81.00"},198.25,"<1","N/A","http://selleckchem.com/products/cholic-acid.html","C24H40O5","free base","N/A","CC(CCC(O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CC(O)C12C",2.912,1,3,4]
["S3745","Balsalazide disodium","a5","L8000-10","in 10mM DMSO","Immunology & Inflammation related,Interleukins,STAT","Immunology & Inflammation","Balsalazide Disodium is the disodium salt form of balsalazide, an aminosalicylate and oral prodrug that is enzymatically cleaved in the colon to produce the anti-inflammatory agent mesalazine. Balsalazide Disodium suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway.",437.31,"150399-21-6",{"v":87,"d":"87.00"},198.94,{"v":87,"d":"87.00"},198.94,"http://selleckchem.com/products/balsalazide-disodium.html","C17H13N3O6.2H2O.2Na","disodium salt dihydrate","N/A","O.O.[Na+].[Na+].OC1=CC=C(C=C1C([O-])=O)N=NC2=CC=C(C=C2)C(=O)NCCC([O-])=O",-0.838,3,2,7]
["S3751","Quinidine hemisulfate hydrate","b5","L8000-10","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Quinidine hemisulfate hydrate(Chinidin, Pitayine, β-quinine, (+)-quinidine) acts as a blocker of voltage-gated sodium channels, also an antimuscarinic and antimalarial.",391.47,"6591-63-5",{"v":100,"d":"100.00"},154.12,{"v":9,"d":"9.00"},13.87,"http://selleckchem.com/products/quinidine-sulfate.html","C20H24N2O2.1/2H2SO4.H2O","hemisulfate hydrate","Chinidin Sodium, Pitayine Sodium, β-quinine Sodium, (+)-quinidine Sodium","O.O.COC1=CC2=C(C=C1)N=CC=C2C(O)C3CC4CCN3CC4C=C.COC5=CC6=C(C=C5)N=CC=C6C(O)C7CC8CCN7CC8C=C.O[S](O)(=O)=O",4.446,4,2,8]
["S3758","Sinomenine hydrochloride","d5","L8000-10","in 10mM DMSO","Autophagy,Immunology & Inflammation related","Immunology & Inflammation","Sinomenine (SN, Cucoline, Kukoline, Sabianine A), extracted from the Chinese medicinal plant, sinomenium acutum, is a potent anti-inflammatory and neuroprotective agent.",365.85,"6080-33-7",{"v":73,"d":"73.00"},199.54,"N/A","N/A","http://selleckchem.com/products/sinomenine-hydrochloride.html","C19H23NO4.HCl","hydrochloride","Cucoline hydrochloride, Kukoline hydrochloride, Sabianine A hydrochloride","Cl.COC1=C(O)C2=C(CC3C4C=C(OC)C(=O)CC24CCN3C)C=C1",2.056,3,1,2]
["S3759","Norcantharidin","e5","L8000-10","in 10mM DMSO","c-Met,EGFR","Protein Tyrosine Kinase","Norcantharidin (Endothall anhydride) is a synthetic anticancer compound which is a dual inhibitor for c-Met and EGFR in human colon cancers.",168.15,"29745-04-8",{"v":33,"d":"33.00"},196.25,"N/A","N/A","http://selleckchem.com/products/norcantharidin.html","C8H8O4","free base","Endothall anhydride","O=C1OC(=O)C2C3CCC(O3)C12",-0.117,4,0,0]
["S3763","Cinnamaldehyde","f5","L8000-10","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Cinnamaldehyde is a flavonoid that is naturally synthesized by the shikimate pathway. Its supplementation can improve glucose and lipid homeostasis in diabetic animals; a TRPA1 agonist.",132.16,"14371-10-9","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/cinnamaldehyde.html","C9H8O","free base","N/A","O=C\\C=C\\C1=CC=CC=C1",1.949,1,0,2]
["S3766","Tanshinone IIA sulfonate sodium","g5","L8000-10","in 10mM DMSO","Calcium Channel,P2 Receptor,P450 (e.g. CYP17)","Metabolism","Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivative of tanshinone IIA isolated as the main pharmacologically active natural compound from a traditional Chinese herbal medicine, the dried root of Salvia miltiorrhiza Bunge known as Danshen. Sodium tanshinone IIA sulfonate (STS) is a potent negative allosteric modulator of the human purinergic receptor P2X7. Sodium tanshinone IIA sulfonate (STS) inhibits the activity of CYP3A4 and store-operated Ca2+ entry (SOCE) through store-operated Ca2+ channels (SOCC) via downregulating the expression of transient receptor potential canonical proteins (TRPC).",396.39,"69659-80-9",{"v":79,"d":"79.00"},{"v":199.3,"d":"199.30"},"N/A","N/A","http://selleckchem.com/products/tanshinone-iia-sulfonate-sodium.html","C19H17O6S.Na","sodium salt","N/A","[Na+].CC1=C(OC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C)[S]([O-])(=O)=O",1.873,3,0,1]
["S3769","Palmatine","h5","L8000-10","in 10mM DMSO","AChR","Neuronal Signaling","Palmatine (Berbericinine, Burasaine), an isoquinoline alkaloid, has sedative, antidepressant, antioxidative, anti-ulcerative, antacid, anticancer, and anti-metastatic activities.",{"v":352.4,"d":"352.40"},"3486-67-7",{"v":70,"d":"70.00"},198.64,"N/A","N/A","http://selleckchem.com/products/palmatine.html","C21H22NO4","free base","Berbericinine, Burasaine","COC1=CC2=C(C=C1OC)C3=CC4=C(C=[N+]3CC2)C(=C(OC)C=C4)OC",4.161,4,0,4]
["S3774","Dehydroandrographolide Succinate Potasium Salt","a6","L8000-10","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Dehydroandrographolide Succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect.",570.67,"76958-99-1",{"v":10,"d":"10.00"},17.52,"N/A","N/A","http://selleckchem.com/products/dehydroandrographolide-succinate-potasium-salt.html","C28H35O10.K","potassium salt","N/A","[K+].CC1(COC(=O)CCC([O-])=O)C(CCC2(C)C1CCC(=C)C2\\C=C\\C3=CCOC3=O)OC(=O)CCC(O)=O",1.553,7,0,13]
["S3776","Sophoricoside","b6","L8000-10","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Sophoricoside (SOPH) is an isoflavone isolated from Sophora japonica (Leguminosae) with numerous pharmacological effects, including anti- inflammatory, anti-cancer and immunosuppressive effects.",432.38,"152-95-4",{"v":86,"d":"86.00"},{"v":198.9,"d":"198.90"},"N/A","N/A","http://selleckchem.com/products/sophoricoside.html","C21H20O10","Isoflavone glycoside","N/A","OCC1OC(OC2=CC=C(C=C2)C3=COC4=C(C(=CC(=C4)O)O)C3=O)C(O)C(O)C1O",{"v":0.21,"d":"0.210"},4,6,4]
["S3779","cis-Anethole","c6","L8000-10","in 10mM DMSO","Others","Others","Anethole ((Z)-Anethole, Cis-p-Propenylanisole, Cis-p-Anethole) has two isomers, the cis(Z) isomer being 15-38 times more toxic to animal than the trans(E) isomer. cis-Anethole is found in anise and Only a low level is permitted in flavours.",{"v":148.2,"d":"148.20"},"104-46-1","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/cis-anethole.html","C10H12O","free base","(Z)-Anethole, Cis-p-Propenylanisole, Cis-p-Anethole","COC1=CC=C(\\C=C\\C)C=C1",2.767,1,0,2]
["S3785","Notoginsenoside R1","d6","L8000-10","in 10mM DMSO","Akt,ERK,PAI-1,PI3K","Metabolism","Notoginsenoside R1 (Sanchinoside R1) is the main ingredient with cardiovascular activity in Panax notoginseng. It inhibits TNF-α-induced PAI-1 overexpression via extracellular signal-related kinases (ERK1/2) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling pathways.",933.13,"80418-24-2",{"v":100,"d":"100.00"},107.17,"N/A","N/A","http://selleckchem.com/products/notoginsenoside-r1.html","C47H80O18","free base","Sanchinoside R1, NG-R1, NGR1","CC(C)=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C2CCC3(C)C2C(O)CC4C5(C)CCC(O)C(C)(C)C5C(CC34C)OC6OC(CO)C(O)C(O)C6OC7OCC(O)C(O)C7O",{"v":-0.11,"d":"-0.110"},6,12,12]
["S3788","Carvacrol","e6","L8000-10","in 10mM DMSO","AChR","Neuronal Signaling","Carvacrol (Cymophenol), monoterpenic phenol isomeric with thymol, has diverse activities such as antimicrobial, antitumor, an-timutagenic, antigenotoxic, analgesic, antispasmodic, anti-inflammatory, angiogenic, antiparasitic, antiplatelet, AChE inhibitory, antielastase, insecticidal, antihepatotoxic and hepatoprotective activities.",150.22,"499-75-2","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/carvacrol.html","C10H14O","free base","cymophenol","CC(C)C1=CC=C(C)C(=C1)O",3.268,0,1,1]
["S3794","Palmitic acid","f6","L8000-10","in 10mM DMSO","Others","Others","Palmitic acid (Hexadecanoic acid, Cetylic acid) is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity.",256.42,"57-10-3",{"v":51,"d":"51.00"},198.89,"N/A","N/A","http://selleckchem.com/products/palmitic-acid.html","C16H32O2","free base","hexadecanoic acid, Cetylic acid","CCCCCCCCCCCCCCCC(O)=O",6.393,1,0,14]
["S3802","Trigonelline Hydrochloride","g6","L8000-10","in 10mM DMSO","Bacterial","Microbiology","Trigonelline (Nicotinic acid N-methylbetaine, Coffearine, Gynesine), a major alkaloid component of fenugreek, has hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities, and also has been shown to reduce diabetic auditory neuropathy and platelet aggregation.",{"v":173.6,"d":"173.60"},"6138-41-6",{"v":18,"d":"18.00"},103.69,"N/A","N/A","http://selleckchem.com/products/trigonelline-hydrochloride.html","C7H8NO2.Cl","chloride","Nicotinic acid N-methylbetaine Hydrochloride, Coffearine Hydrochloride, Gynesine Hydrochloride","[Cl-].C[N+]1=CC(=CC=C1)C(O)=O",{"v":-1.61,"d":"-1.610"},1,0,1]
["S3805","Stevioside","h6","L8000-10","in 10mM DMSO","Others","Others","Stevioside is a natural sweetener extracted from leaves of Stevia rebaudiana (Bertoni) Bertoni.",804.87,"57817-89-7",{"v":100,"d":"100.00"},124.24,"N/A","N/A","http://selleckchem.com/products/stevioside.html","C38H60O18","free base","N/A","CC12CCCC(C)(C1CCC34CC(=C)C(CCC23)(C4)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O",-1.729,7,11,10]
["S3807","Dehydroandrographolide","a7","L8000-10","in 10mM DMSO","Chloride Channel","Transmembrane Transporters","Dehydroandrographolide, isolated from Andrographis paniculata (Burm. F.) Nees (Chuan-xin-lian), is a novel TMEM16A inhibitor and possesses multiple pharmacological activities, including anti-inflammation, anti-cancer, anti-bacterial, anti-virus and anti-hepatitis activity.",332.43,"134418-28-3",{"v":66,"d":"66.00"},198.54,"N/A","N/A","http://selleckchem.com/products/dehydroandrographolide.html","C20H28O4","free base","N/A","CC1(CO)C(O)CCC2(C)C(C\\C=C3/C=COC3=O)C(=C)CCC12",2.502,2,2,3]
["S3809","Imperatorin","b7","L8000-10","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Imperatorin (Ammidin, Marmelosin, Pentosalen, 8-Isoamylenoxypsoralen), a naturally occurring psoralen-type furanocoumarin, is a potent myorelaxant agent and acts as a calcium antagonist on vascular smooth muscle.",270.28,"482-44-0",{"v":54,"d":"54.00"},199.79,"N/A","N/A","http://selleckchem.com/products/imperatorin.html","C16H14O4","free base","Ammidin, Marmelosin, Pentosalen, 8-Isoamylenoxypsoralen, 8-Isopentenyloxypsoralene","CC(C)=CCOC1=C2OC(=O)C=CC2=CC3=C1OC=C3",3.652,4,0,3]
["S3810","Scutellarin","c7","L8000-10","in 10mM DMSO","Akt,NF-κB,STAT","JAK/STAT","Scutellarin (Breviscapine, Breviscapin, Scutellarein-7-glucuronide), the major active principal flavonoids extracted from the Chinese herbal medicines Scutellaria baicalensis and Erigeron breviscapus (Vant.) Hand-Mazz, has many pharmacological effects, such as antioxidant, antitumor, antiviral, and antiinflammatory activities. Scutellarin can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts.",462.36,"27740-01-8",{"v":50,"d":"50.00"},108.14,"N/A","N/A","http://selleckchem.com/products/scutellarin.html","C21H18O12","free base","Breviscapine, Breviscapin, Scutellarein-7-glucuronide","OC1C(O)C(OC(C1O)C(O)=O)OC2=CC3=C(C(=O)C=C(O3)C4=CC=C(O)C=C4)C(=C2O)O",0.366,5,6,4]
["S3811","Ginsenoside Re","d7","L8000-10","in 10mM DMSO","Beta Amyloid,JNK,NF-κB","Neuronal Signaling","Ginsenoside Re (Ginsenoside B2, Panaxoside Re, Sanchinoside Re, Chikusetsusaponin Ivc), an extract from Panax notoginseng, is a major ginsenoside in ginseng and belongs to 20(S)-protopanaxatriol group. It has diverse in vitro and in vivo effects, including vasorelaxant, antioxidant, antihyperlipidemic, and angiogenic actions. Ginsenoside Re decreases the β-amyloid protein (Aβ). Ginsenoside Re plays a role in antiinflammation through inhibition of JNK and NF-κB.",947.15,"52286-59-6",{"v":100,"d":"100.00"},105.58,"N/A","N/A","http://selleckchem.com/products/ginsenoside-re.html","C48H82O18","free base","Panaxoside Re, Sanchinoside Re, Chikusetsusaponin Ivc","CC1OC(OC2C(O)C(O)C(CO)OC2OC3CC4(C)C(CC(O)C5C(CCC45C)C(C)(CCC=C(C)C)OC6OC(CO)C(O)C(O)C6O)C7(C)CCC(O)C(C)(C)C37)C(O)C(O)C1O",0.267,6,12,12]
["S3817","Harmine hydrochloride","e7","L8000-10","in 10mM DMSO","5-HT Receptor,ADC Cytotoxin,DYRK,MAO","Cell Cycle","Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγ and cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.",248.71,"343-27-1",{"v":21,"d":"21.00"},84.44,"N/A","N/A","http://selleckchem.com/products/harmine-hydrochloride.html","C13H12N2O.HCl","hydrochloride","Telepathine hydrochloride","Cl.COC1=CC2=C(C=C1)C3=CC=NC(=C3[NH]2)C",{"v":2.82,"d":"2.820"},2,1,1]
["S3835","Loganin","f7","L8000-10","in 10mM DMSO","AChR,BACE,BChE","Neuronal Signaling","Loganin (Loganoside) is an iridoid glycoside first isolated from the seeds of Strychnos nux-vomica, a member of the Loganiaceae family. It is a non-competitive inhibitor of BACE1 with IC50 of 47.97 μM an also inhibits AChE and BChE with IC50 values of 3.95 μM and 33.02 μM, respectively.",390.38,"18524-94-2",{"v":78,"d":"78.00"},199.81,"N/A","N/A","http://selleckchem.com/products/loganin.html","C17H26O10","free base","Loganoside","COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C3C(C)C(O)CC13",-1.895,5,5,5]
["S3842","Isoquercitrin","g7","L8000-10","in 10mM DMSO","Wnt/beta-catenin","Stem Cells & Wnt","Isoquercitrin (Hirsutrin, 3-Glucosylquercetin, Quercetin 3-o-glucopyranoside), a flavonoid compound with anticancer activity isolated from Bidens bipinnata L, is an inhibitor of Wnt/β-catenin that acts downstream of the β-catenin nuclear translocation.",464.38,"482-35-9",{"v":92,"d":"92.00"},198.11,"N/A","N/A","http://selleckchem.com/products/isoquercitrin.html","C21H20O12","free base","Hirsutrin, 3-Glucosylquercetin, Quercetin 3-o-glucopyranoside","OCC1OC(OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(O)C=C4)O)C(O)C(O)C1O",{"v":-0.3,"d":"-0.300"},4,8,4]
["S3846","Eupatilin","h7","L8000-10","in 10mM DMSO","PPAR","Metabolism","Eupatilin (NSC 122413), a major flavonoid from Artemisia plants, possesses various beneficial biological effects including anti-inflammation, anti-tumor, anti-cancer, anti-allergy, and anti-oxidation activity. Eupatilin, a lipophilic flavonoid isolated from Artemisia species, is a PPARα agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities.",344.32,"22368-21-4",{"v":68,"d":"68.00"},197.49,"N/A","N/A","http://selleckchem.com/products/eupatilin.html","C18H16O7","free base","NSC 122413","COC1=CC=C(C=C1OC)C2=CC(=O)C3=C(O2)C=C(O)C(=C3O)OC",2.603,5,2,4]
["S3847","Panaxatriol","a8","L8000-10","in 10mM DMSO","Others","Others","Panaxatriol is a triterpene sapogenin originally found in species of Panax (ginseng) and exhibits anti-inflammatory, hepatoprotective, anti-arrhythmic, and antioxidative activities.",476.73,"32791-84-7",{"v":95,"d":"95.00"},199.27,"N/A","N/A","http://selleckchem.com/products/panaxatriol.html","C30H52O4","free base","N/A","CC1(C)CCCC(C)(O1)C2CCC3(C)C2C(O)CC4C5(C)CCC(O)C(C)(C)C5C(O)CC34C",4.285,1,3,1]
["S3849","D-Galactose","b8","L8000-10","in 10mM DMSO","Others","Others","D-Galactose (D-Galactopyranose, D-(+)-Galactose) is an aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins and is converted enzymatically into D-glucose for metabolism or polysaccharides for storage. It accelerates senescence in invertebrates and mammals and has been used as a model for aging.",180.16,"59-23-4",{"v":36,"d":"36.00"},199.82,"N/A","N/A","http://selleckchem.com/products/d-galactose.html","C6H12O6","free base","D-Galactopyranose, D-(+)-Galactose","OCC1OC(O)C(O)C(O)C1O",-2.514,1,4,1]
["S3850","Glucosamine sulfate","c8","L8000-10","in 10mM DMSO","Others","Others","Glucosamine sulfate (D-Glucosaminesulfate, D-Glucosamine sulphate) is a dietary supplement commonly used in the treatment of osteoarthritis. It is a type of glycosaminoglycan, which is a naturally occurring major component of joint cartilage and joint fluid.",277.25,"29031-19-4",{"v":4,"d":"4.00"},14.43,{"v":55,"d":"55.00"},198.38,"http://selleckchem.com/products/glucosamine-sulfate.html","C6H13NO5.H2SO4","sulfate","D-Glucosaminesulfate, D-Glucosamine sulphate","NC(C=O)C(O)C(O)C(O)CO.O[S](O)(=O)=O",-3.688,1,5,5]
["S3851","Camphor","d8","L8000-10","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Camphor (2-Bornanone, Bornan-2-one, 2-Camphanone, Formosa) is a bicyclic monoterpene ketone found widely in plants, especially cinnamomum camphora and used topically as a skin antipruritic and as an anti-infective agent.",152.23,"76-22-2",{"v":30,"d":"30.00"},197.07,"N/A","N/A","http://selleckchem.com/products/camphor.html","C10H16O","free base","2-Bornanone, Bornan-2-one, 2-Camphanone, Formosa","CC1(C)C2CCC1(C)C(=O)C2",2.075,1,0,0]
["S3856","Allantoin","e8","L8000-10","in 10mM DMSO","Others","Others","Allantoin (Glyoxyldiureide, 5-Ureidohydantoin), produced from uric acid, is a major metabolic intermediate in most organisms including animals, plants and bacteria.",158.12,"97-59-6",{"v":7,"d":"7.00"},44.27,"N/A","N/A","http://selleckchem.com/products/allantoin.html","C4H6N4O3","free base","Glyoxyldiureide, 5-Ureidohydantoin","NC(=O)NC1NC(=O)NC1=O",{"v":-1.76,"d":"-1.760"},3,4,1]
["S3868","Harmine","f8","L8000-10","in 10mM DMSO","MAO,PPAR","Metabolism","Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγ and cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.",212.25,"442-51-3",{"v":42,"d":"42.00"},197.88,"N/A","N/A","http://selleckchem.com/products/harmine.html","C13H12N2O","free base","Telepathine","COC1=CC2=C(C=C1)C3=CC=NC(=C3[NH]2)C",2.438,2,1,1]
["S3870","D-Pinitol","g8","L8000-10","in 10mM DMSO","Influenza Virus","Microbiology","D-pinitol (Methylinositol, Pinitol, 3-O-Methyl-D-chiro-inositol, D-(+)-Pinitol, Inzitol) is a naturally occurring compound derived from soy and has significant pharmacological activitites such as inhibition of the T-helpercell-1 response, antiviral, larvicidal, antiinflammatory, antihyperlipidemic, cardioprotective, inhibition of ovalbumin-induced airway inflammation and antioxidant.",194.18,"10284-63-6",{"v":38,"d":"38.00"},195.69,"N/A","N/A","http://selleckchem.com/products/d-pinitol.html","C7H14O6","free base","Methylinositol, Pinitol, 3-O-Methyl-D-chiro-inositol, D-(+)-Pinitol, Inzitol","COC1C(O)C(O)C(O)C(O)C1O",-2.656,1,5,1]
["S3876","Indigo","h8","L8000-10","in 10mM DMSO","Dyes","Others","Indigo (Indigotin) dye is an organic compound with a distinctive blue color. It is extracted from the leaves of certain plants or synthetic.",262.26,"482-89-3",{"v":33,"d":"33.00"},125.83,"N/A","N/A","http://selleckchem.com/products/indigo.html","C16H10N2O2","free base","Indigotin","O=C1\\C(NC2=C1C=CC=C2)=C\\3NC4=C(C=CC=C4)C3=O",2.106,2,2,0]
["S3883","Protopine","a9","L8000-10","in 10mM DMSO","ADC Cytotoxin,Calcium Channel","Transmembrane Transporters","Protopine (Corydinine, Fumarine, Biflorine, Macleyine), an alkaloid present in different plants, has been shown to exhibit a number of activities, such as inhibition of calcium influx through both voltage and receptor-operated channels and inhibition of rabbit blood platelet aggregation. It also possesses anti-cholinergic and anti-histaminic as well as anti-bacterial activities.",353.37,"130-86-9",{"v":30,"d":"30.00"},{"v":84.9,"d":"84.90"},"N/A","N/A","http://selleckchem.com/products/protopine.html","C20H19NO5","free base","Corydinine, Fumarine, Biflorine, Macleyine","CN1CCC2=C(C=C3OCOC3=C2)C(=O)CC4=C(C1)C5=C(OCO5)C=C4",2.953,5,0,0]
["S3885","Pyrogallol","b9","L8000-10","in 10mM DMSO","ROS","Immunology & Inflammation","Pyrogallol (1,2,3-trihydroxybenzene), an organic compound belonging to the phenol family, used as a photographic film developer and in the preparation of other chemicals. It is known to be a superoxide anion generator and ROS inducer.",126.11,"87-66-1",{"v":25,"d":"25.00"},198.24,"N/A","N/A","http://selleckchem.com/products/pyrogallol.html","C6H6O3","free base","1,2,3-trihydroxybenzene","OC1=C(O)C(=CC=C1)O",1.103,0,3,0]
["S3887","α-L-Rhamnose monohydrate","c9","L8000-10","in 10mM DMSO","Others","Others","α-L-Rhamnose monohydrate (6-deoxy-L-mannose monohydrate, α-L-Rhamnopyranose monohydrate) is used as a starting material for the production of furanones. It is an important material involved in the reaction of flavors developed during the preparation of various foods like bread, grilled meats, etc.",182.17,"6155-35-7",{"v":36,"d":"36.00"},197.62,"N/A","N/A","https://www.selleckchem.com/products/a-l-rhamnose-monohydrate.html","C6H12O5.H2O","hydrate","6-deoxy-L-mannose monohydrate, α-L-Rhamnopyranose monohydrate","O.CC1OC(O)C(O)C(O)C1O",-1.833,1,3,0]
["S3889","Arteether","d9","L8000-10","in 10mM DMSO","Parasite","Microbiology","Arteether is a well-known antimalarial drug which acts by producing free radicals within the malarial parasite.",{"v":312.4,"d":"312.40"},"75887-54-6",{"v":62,"d":"62.00"},198.46,"N/A","N/A","http://selleckchem.com/products/arteether.html","C17H28O5","free base","N/A","CCOC1OC2OC3(C)CCC4C(C)CCC(C1C)C24OO3",2.378,5,0,2]
["S3892","Isopsoralen","e9","L8000-10","in 10mM DMSO","ADC Cytotoxin,Immunology & Inflammation related","Immunology & Inflammation","Isopsoralen (Angelicin), also known as angelicin, is a constituent of roots and leaves of angelica with anti-inflammatory activity and regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways. It also shows antiviral activity against gammaherpesviruses.",186.16,"523-50-2",{"v":14,"d":"14.00"},{"v":75.2,"d":"75.20"},"N/A","N/A","http://selleckchem.com/products/isopsoralen.html","C11H6O3","free base","angelicin","O=C1OC2=C(C=C1)C=CC3=C2C=CO3",2.203,3,0,0]
["S3893","Bornyl acetate","f9","L8000-10","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Bornyl acetate (Isobornyl, Bornyl acetic ether, 2-Camphanol), the main volatile constituent in numerous conifer oils and some Chinese traditional herbs, exhibits anti-inflammatory property and it is used as an analgesic.",196.29,"76-49-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/bornyl-acetate.html","C12H20O2","free base","Isobornyl acetate, Bornyl acetic ether, 2-Camphanol acetate","CC(=O)OC1CC2CCC1(C)C2(C)C",2.354,2,0,2]
["S3895","Sophoridine","g9","L8000-10","in 10mM DMSO","Apoptosis related","Apoptosis","Sophoridine (5-Epidihydrosophocarpine, Dihydro-5-episophocarpine), a natural product obtained from medicinal plants, has a variety of pharmacological effects, including anti-cancer and anti-arrhythmia, and affects the immune and central nervous systems.",248.36,"6882-68-4",{"v":49,"d":"49.00"},197.29,"N/A","N/A","http://selleckchem.com/products/sophoridine.html","C15H24N2O","free base","5-Epidihydrosophocarpine, Dihydro-5-episophocarpine","O=C1CCCC2C3CCCN4CCCC(CN12)C34",1.417,1,0,0]
["S3898","Hydroxy Camptothecine","h9","L8000-10","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Hydroxy Camptothecine (10-Hydroxycamptothecin, Hydroxycamptothecine) is a cell-permeable powerful DNA topoisomerase I inhibitor. It has selective inhibitory effect on the phosphorylation of histone H1 and H3, but less effect on other histones.",364.35,"64439-81-2",{"v":29,"d":"29.00"},79.59,"N/A","N/A","http://selleckchem.com/products/hydroxy-camptothecine.html","C20H16N2O5","free base","10-Hydroxycamptothecin, Hydroxycamptothecine","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=CC5=C(C=CC(=C5)O)N=C34)C2=O",1.504,4,1,1]
["S3899","Hederagenin","a10","L8000-10","in 10mM DMSO","COX,NF-κB,NOS","Immunology & Inflammation","Hederagenin (Caulosapogenin, Hederagenol, Hederagenic acid, Astrantiagenin E) is a highly water insoluble triterpenoid compound that can be found in various plants including Hedera helix and Chenopodium quinoa. It exhibits a variety of biological activities, including potent antitumor properties both in vitro and in vivo. Hederagenin inhibits LPS-stimulated expression of iNOS, COX-2, and NF-κB.",{"v":472.7,"d":"472.70"},"465-99-6",{"v":94,"d":"94.00"},198.86,"N/A","N/A","http://selleckchem.com/products/hederagenin.html","C30H48O4","free base","Caulosapogenin, Hederagenol, Hederagenic acid, Astrantiagenin E","CC1(C)CCC2(CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(CO)C5CCC34C)C2C1)C(O)=O",5.356,1,2,2]
["S3901","Astragaloside IV","b10","L8000-10","in 10mM DMSO","Akt,ERK,JNK,mTOR,NF-κB","MAPK","Astragaloside IV (AST-IV, AS-IV) is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine. It has various effect on the cardiovascular, immune, digestive, and nervous systems. AS-IV suppresses activation of p-Akt, p-mTOR, p-NF-κB and p-Erk1/2.",784.97,"84687-43-4",{"v":100,"d":"100.00"},127.39,"N/A","N/A","http://selleckchem.com/products/sastragaloside-iv.html","C41H68O14","free base","AST-IV, AS-IV","CC(C)(O)C1CCC(C)(O1)C2C(O)CC3(C)C4CC(OC5OC(CO)C(O)C(O)C5O)C6C(C)(C)C(CCC67CC47CCC23C)OC8OCC(O)C(O)C8O",-0.348,5,8,7]
["S3909","Catalpol","c10","L8000-10","in 10mM DMSO","Others","Others","Catalpol (Catalpinoside, Digitalis purpurea L), an iridoid glucoside contained richly in the roots of the small flowering plant species Rehmannia glutinosa Libosch, has been shown to have antioxidation, anti-inflammation, anti-apoptosis and other neuroprotective properties and plays a role in neuroprotection against hypoxic/ischemic injury, AD and PD in both in vivo and in vitro models.",362.33,"2415-24-9",{"v":72,"d":"72.00"},198.71,"N/A","N/A","http://selleckchem.com/products/catalpol.html","C15H22O10","free base","Catalpinoside, Digitalis purpurea L","OCC1OC(OC2OC=CC3C(O)C4OC4(CO)C23)C(O)C(O)C1O",-3.581,4,6,4]
["S3914","α-Hederin","d10","L8000-10","in 10mM DMSO","Others","Apoptosis","α-hederin is a water-soluble pentacyclic triterpenoid saponin which has shown hemolytic and apoptotic properties.",750.96,"27013-91-8",{"v":100,"d":"100.00"},133.16,"N/A","N/A","http://selleckchem.com/products/alpha-hederin.html","C41H66O12","free base","N/A","CC1OC(OC2C(O)C(O)COC2OC3CCC4(C)C(CCC5(C)C4CC=C6C7CC(C)(C)CCC7(CCC56C)C(O)=O)C3(C)CO)C(O)C(O)C1O",3.261,5,6,6]
["S3921","Lathyrol","e10","L8000-10","in 10mM DMSO","Others","Others","Lathyrol is a natural product that is used for cancer treatment.",334.45,"34420-19-4",{"v":85,"d":"85.00"},254.15,"N/A","N/A","http://selleckchem.com/products/lathyrol.html","C20H30O4","free base","N/A","CC1CC2(O)C(C1O)C(O)C(=C)CCC3C(\\C=C(C)\\C2=O)C3(C)C",2.421,1,2,0]
["S3923","Ginsenoside Rg1","f10","L8000-10","in 10mM DMSO","Beta Amyloid,NF-κB","Neuronal Signaling","Ginsenoside Rg1 (Ginsenoside A2, Panaxoside A, Panaxoside Rg1, Sanchinoside C1, Sanchinoside Rg1), one of the major active components of ginseng, is identified as a protopanaxatriol-type and has pharmacological actions such as neuroprotective and anti-tumor effects on various cancer types. Ginsenoside Rg1 reduces cerebral Aβ levels and NF-κB nuclear translocation.",801.01,"22427-39-0",{"v":100,"d":"100.00"},124.84,"N/A","N/A","http://selleckchem.com/products/ginsenoside-rg1.html","C42H72O14","free base","Ginsenoside A2, Panaxoside A, Panaxoside Rg1, Sanchinoside C1, Sanchinoside Rg1","CC(C)=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C2CCC3(C)C2C(O)CC4C5(C)CCC(O)C(C)(C)C5C(CC34C)OC6OC(CO)C(O)C(O)C6O",1.126,4,10,10]
["S3924","Ginsenoside Rb1","g10","L8000-10","in 10mM DMSO","ATPase,IFN,IRAK,NF-κB,NOS,TLR,TNF-alpha","Transmembrane Transporters","Ginsenoside Rb1 (Gypenoside Ⅲ) is a protopanaxadiol that has diverse in vitro and in vivo effects, including neuroprotective, anti-inflammatory, and anti-obesity actions. Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65. Ginsenoside Rb1 reduces the expressions of TLR3, TLR4 and TRAF-6, and down-regulates the levels of TNF-α, IFN-β and iNOS.",1109.29,"41753-43-9",{"v":100,"d":"100.00"},90.15,"N/A","N/A","http://selleckchem.com/products/ginsenoside-rb1.html","C54H92O23","free base","Gypenoside Ⅲ","CC(C)=CCCC(C)(OC1OC(COC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CCC45C",-1.198,8,15,16]
["S3925","(-)-Epicatechin gallate","h10","L8000-10","in 10mM DMSO","COX","Immunology & Inflammation","(-)-Epicatechin gallate (ECG) is an inhibitor of cyclooxygenase-1 (COX-1) with IC50 of 7.5 μM.",442.37,"1257-08-5",{"v":88,"d":"88.00"},198.93,"N/A","N/A","http://selleckchem.com/products/epicatechin-gallate.html","C22H18O10","free base","(−)-ECG, (−)-Epicatechin 3-gallate, (−)-Epicatechin-3-O-gallate","OC1=CC2=C(CC(OC(=O)C3=CC(=C(O)C(=C3)O)O)C(O2)C4=CC=C(O)C(=C4)O)C(=C1)O",3.339,3,7,4]
["S3926","Forsythin","a11","L8000-10","in 10mM DMSO","PDE","GPCR & G Protein","Forsythin (FOR, Phillyrin) is an active ingredient extracted from the fruit of the medicinal plant Forsythia suspensa (Thunb.) Vahl and has been shown to have antioxidant, antibacterial and antiinflammatory properties.",534.55,"487-41-2",{"v":100,"d":"100.00"},187.07,"N/A","N/A","http://selleckchem.com/products/forsythin.html","C27H34O11","free base","Phillyrin","COC1=CC=C(C=C1OC)C2OCC3C2COC3C4=CC(=C(OC5OC(CO)C(O)C(O)C5O)C=C4)OC",0.479,7,4,8]
["S3927","Swertiamarin","b11","L8000-10","in 10mM DMSO","Others","Others","Swertiamarin (Swertiamaroside) is a common secoiridoid found among the members of Gentianaceae with anti-inflammatory, anticancer, hypoglycemic and hypolipidemic activities.",374.34,"17388-39-5",{"v":74,"d":"74.00"},197.68,"N/A","N/A","http://selleckchem.com/products/swertiamarin.html","C16H22O10","free base","Swertiamaroside","OCC1OC(OC2OC=C3C(=O)OCCC3(O)C2C=C)C(O)C(O)C1O",-2.381,5,4,4]
["S3930","Liquiritin","c11","L8000-10","in 10mM DMSO","AKR1C","Immunology & Inflammation","Liquiritin (LIQ, Liquiritoside, Liquiritigenin-4'-O-glucoside) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities.",418.39,"551-15-5",{"v":100,"d":"100.00"},239.01,"N/A","N/A","http://selleckchem.com/products/liquiritin.html","C21H22O9","free base","Liquiritoside, Liquiritigenin-4'-O-glucoside","OCC1OC(OC2=CC=C(C=C2)C3CC(=O)C4=C(O3)C=C(O)C=C4)C(O)C(O)C1O",0.686,4,5,4]
["S3935","Nonivamide","d11","L8000-10","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Nonivamide (pelargonic acid vanillylamide, Pseudocapsaicin, Vanillyl-N-nonylamide), present in chili peppers, is commonly manufactured synthetically and used as a food additive to add pungency to seasonings, flavorings, and spice blends. Nonivamide is a agonist, which exhibits 4d-EC50 value of 5.1 mg/L in static toxicity tests.",{"v":293.4,"d":"293.40"},"2444-46-4",{"v":58,"d":"58.00"},197.68,"<1","N/A","https://www.selleckchem.com/products/nonivamide.html","C17H27NO3","free base","pelargonic acid vanillylamide, Pseudocapsaicin, Vanillyl-N-nonylamide","CCCCCCCCC(=O)NCC1=CC(=C(O)C=C1)OC",4.103,2,2,10]
["S3944","Valproic acid (VPA)","e11","L8000-10","in 10mM DMSO","Autophagy,HDAC,Mitophagy,Notch,PGC-1α","Epigenetics","Valproic acid (VPA, 2-Propylvaleric Acid, Valproate) is a fatty acid with anticonvulsant properties used in the treatment of epilepsy. It is also a histone deacetylase (HDAC) inhibitor and is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α. Valproic acid activates Notch-1 signaling.",144.21,"99-66-1","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/valproic-acid.html","C8H16O2","free base","2-Propylvaleric Acid, Valproate","CCCC(CCC)C(O)=O",2.749,1,0,5]
["S3945","L-Cycloserine","f11","L8000-10","in 10mM DMSO","Transferase","Metabolism","L-Cycloserine (Levcycloserine, Levcicloserina, Levcycloserinum, (-)-Cycloserine, (S)-Cycloserine) is a potent inhibitor of the sphingolipid pathway via inhibiting 3-ketodihydrosphingosine synthetase. It also inhibits HIV-1 cytopathic effects, replication, and infectivity.",102.09,"339-72-0",{"v":8,"d":"8.00"},78.36,{"v":20,"d":"20.00"},195.91,"http://selleckchem.com/products/l-cycloserine.html","C3H6N2O2","free base","Levcycloserine, Levcicloserina, Levcycloserinum, (-)-Cycloserine, (S)-Cycloserine","NC1CONC1=O",-1.788,2,2,0]
["S3951","Tannic acid","g11","L8000-10","in 10mM DMSO","CXCR","Immunology & Inflammation","Tannic acid (Gallotannic acid), a polyphenolic compound, is a CXCL12/CXCR4 inhibitor with antiangiogenic, anti-inflammatory and antitumor activity.",{"v":1701.2,"d":"1701.20"},"1401-55-4",{"v":100,"d":"100.00"},58.78,"N/A","N/A","http://selleckchem.com/products/tannic-acid.html","C76H52O46","free base","Gallotannic acid","OC1=CC(=CC(=C1O)O)C(=O)OC2=C(O)C(=CC(=C2)C(=O)OCC3OC(OC(=O)C4=CC(=C(O)C(=C4)O)OC(=O)C5=CC(=C(O)C(=C5)O)O)C(OC(=O)C6=CC(=C(O)C(=C6)O)OC(=O)C7=CC(=C(O)C(=C7)O)O)C(OC(=O)C8=CC(=C(O)C(=C8)O)OC(=O)C9=CC(=C(O)C(=C9)O)O)C3OC(=O)C%10=CC(=C(O)C(=C%10)O)OC(=O)C%11=CC(=C(O)C(=C%11)O)O)O",8.813,21,25,31]
["S3956","Tetramethylpyrazine","h11","L8000-10","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Tetramethylpyrazine (ligustrazine, TMP) is a natural compound isolated from Chinese herbal medicine Ligusticum wallichii (Chuan Xiong) with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.",136.19,"1124-11-4",{"v":27,"d":"27.00"},198.25,"N/A","N/A","http://selleckchem.com/products/tetramethylpyrazine.html","C8H12N2","free base","ligustrazine","CC1=NC(=C(C)N=C1C)C",0.659,2,0,0]
["S3957","Gamma-Oryzanol","a2","L8000-11","in 10mM DMSO","DNA Methyltransferase","Epigenetics","Gamma-oryzanol (GO), a nutriactive phytochemical naturally occurring in crude rice bran oil, is an antioxidant compound used to treat hyperlipidemia, disorders of menopause and to increase the muscle mass.  γ-Oryzanol is a potent DNA methyltransferases (DNMTs) inhibitor in the striatum of mice. γ-Oryzanol significantly inhibits the activities of DNMT1 (IC50=3.2 μM), DNMT3a (IC50=22.3 μM).",602.89,"11042-64-1",{"v":100,"d":"100.00"},165.87,"N/A","N/A","http://selleckchem.com/products/gamma-oryzanol.html","C40H58O4","free base","N/A","COC1=CC(=CC=C1O)/C=C/C(=O)OC2CCC34CC35CCC6(C)C(CCC6(C)C5CCC4C2(C)C)C(C)CCC=C(C)C",9.806,3,1,9]
["S3959","(+)-Borneol","b2","L8000-11","in 10mM DMSO","GABA Receptor","Neuronal Signaling","(+)-Borneol is one of enantiomers of borneol which is a valuable medical material, senior aromatic spice, and chemical material and has been used in food and also folk medicine.",154.25,"464-43-7",{"v":30,"d":"30.00"},194.49,"N/A","N/A","http://selleckchem.com/products/positive-rotation-borneol.html","C10H18O","free base","N/A","CC1(C)C2CCC1(C)C(O)C2",1.975,0,1,0]
["S3966","Nifuratel","c2","L8000-11","in 10mM DMSO","Fungal","Microbiology","Nifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action.",285.28,"4936-47-4",{"v":57,"d":"57.00"},{"v":199.8,"d":"199.80"},"<1","N/A","https://www.selleckchem.com/products/nifuratel.html","C10H11N3O5S","free base","N/A","CSCC1CN(\\N=C\\C2=CC=C(O2)[N+]([O-])=O)C(=O)O1",1.743,4,0,5]
["S3967","Flavone","d2","L8000-11","in 10mM DMSO","Apoptosis related","Apoptosis","Flavone (2-Phenylchromone, 2-Phenyl-4-chromone, 2-Phenyl-4-benzopyron), a class of flavonoids, mainly found in spices and red or purple plant foods with antioxidant, anti-proliferative, anti-tumor, anti-microbial, estrogenic, acetyl cholinesterase, anti-inflammatory activities and are also used in cancer, cardiovascular disease, neurodegenerative disorders etc.",222.24,"525-82-6",{"v":44,"d":"44.00"},197.98,"N/A","N/A","http://selleckchem.com/products/flavone.html","C15H10O2","free base","2-Phenylchromone, 2-Phenyl-4-chromone, 2-Phenyl-4-benzopyron","O=C1C=C(OC2=C1C=CC=C2)C3=CC=CC=C3",3.136,2,0,1]
["S3968","Histamine","e2","L8000-11","in 10mM DMSO","Histamine Receptor","Immunology & Inflammation","Histamine, an organic nitrogenous compound, is involved in local immune responses regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. It is a potent H1 and H2 receptor agonist.",111.15,"51-45-6",{"v":22,"d":"22.00"},197.93,"N/A","N/A","http://selleckchem.com/products/histamine.html","C5H9N3","free base","N/A","NCCC1=C[NH]C=N1",-0.714,1,2,2]
["S3970","Vindoline","f2","L8000-11","in 10mM DMSO","Microtubule Associated","Cytoskeletal Signaling","Vindoline is a chemical precursor to vinblastine and exhibits antimitotic activity by inhibiting microtubule assembly.",456.53,"2182-14-1",{"v":91,"d":"91.00"},199.33,"N/A","N/A","http://selleckchem.com/products/vindoline.html","C25H32N2O6","free base","N/A","CCC12C=CCN3CCC4(C(N(C)C5=C4C=CC(=C5)OC)C(O)(C1OC(C)=O)C(=O)OC)C23",1.935,5,0,6]
["S3974","(+)-Catechin hydrate","h2","L8000-11","in 10mM DMSO","COX","Immunology & Inflammation","(+)-Catechin hydrate is a plant derived polyphenolic anti-oxidants with phytotoxic properties. (+)-Catechin hydrate is a frequent component of traditional herbal remedies, such as Uncaria rhynchophylla.  (+)-Catechin hydrate inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.",290.27,"225937-10-0",{"v":58,"d":"58.00"},199.81,"N/A","N/A","http://selleckchem.com/products/catechin-hydrate.html","C15H14O6.xH2O","hydrate","N/A","OC1CC2=C(OC1C3=CC(=C(O)C=C3)O)C=C(O)C=C2O",2.021,1,5,1]
["S3975","Protocatechuic acid","a3","L8000-11","in 10mM DMSO","Apoptosis related","Apoptosis","Protocatechuic acid (PCA, 3,4-Dihydroxybenzoic acid, Protocatechuate), a dihydroxybenzoic acid, is a type of widely distributed naturally occurring phenolic acid.",154.12,"99-50-3",{"v":30,"d":"30.00"},194.65,"N/A","N/A","http://selleckchem.com/products/protocatechuic-acid.html","C7H6O4","free base","3,4-Dihydroxybenzoic acid, Protocatechuate","OC(=O)C1=CC(=C(O)C=C1)O",0.975,1,2,1]
["S3980","Pyridoxine","b3","L8000-11","in 10mM DMSO","Vitamin","Metabolism","Pyridoxine (Pyridoxol, Vitamin B6, Gravidox), also known as vitamin B6, is a form of vitamin B6 found commonly in food and used as dietary supplement. It is a cofactor for both glutamic acid decarboxylase and GABA transaminase.",169.18,"65-23-6",{"v":33,"d":"33.00"},195.06,"N/A","N/A","http://selleckchem.com/products/pyridoxine.html","C8H11NO3","free base","Pyridoxol, Vitamin B6, Gravidox","CC1=NC=C(CO)C(=C1O)CO",{"v":-0.49,"d":"-0.490"},1,3,2]
["S3982","Batyl alcohol","c3","L8000-11","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Batyl alcohol (Batilol, Stearyl monoglyceride, 1-O-Octadecylglycerol, Batilolum), isolated from shark liver oil, is also present in yellow bone marrow of animals and has been described as an inflammatory agent.",344.57,"544-62-7",{"v":68,"d":"68.00"},197.35,"N/A","N/A","http://selleckchem.com/products/batyl-alcohol.html","C21H44O3","free base","Batilol, Stearyl monoglyceride, 1-O-Octadecylglycerol, Batilolum","CCCCCCCCCCCCCCCCCCOCC(O)CO",6.715,1,2,20]
["S3983","Caryophyllene oxide","d3","L8000-11","in 10mM DMSO","Others","Others","Caryophyllene oxide, an oxygenated terpenoid existed in many plant essential oil, is well known as preservative in food, drugs and cosmetics with anti-inflammatory, anti-carcinogenic and skin penetration enhancing  properties.",220.35,"1139-30-6",{"v":44,"d":"44.00"},199.68,"<1","N/A","http://selleckchem.com/products/caryophyllene-oxide.html","C15H24O","free base","N/A","CC1(C)CC2C1CCC3(C)OC3CCC2=C",3.519,1,0,0]
["S3984","Nordihydroguaiaretic acid (NDGA)","e3","L8000-11","in 10mM DMSO","Apoptosis related,Autophagy,Epigenetic Reader Domain,Ferroptosis,HER2,IGF-1R,Lipoxygenase","Metabolism","Nordihydroguaiaretic acid (NDGA) is a phenolic antioxidant found in the leaves and twigs of the evergreen desert shrub, Larrea tridentata (Sesse and Moc. ex DC) Coville (creosote bush). It is a recognized inhibitor of lipoxygenase (LOX) and has antioxidant and free radical scavenging properties. Nordihydroguaiaretic acid (NDGA) is a cytotoxic insulin-like growth factor-I receptor (IGF-1R)/HER2 inhibitor and induces apoptosis.",302.36,"500-38-9",{"v":60,"d":"60.00"},198.44,"<1","N/A","http://selleckchem.com/products/nordihydroguaiaretic-acid.html","C18H22O4","free base","N/A","CC(CC1=CC=C(O)C(=C1)O)C(C)CC2=CC=C(O)C(=C2)O",4.708,0,4,5]
["S3987","L-Tryptophan","f3","L8000-11","in 10mM DMSO","Others","Others","L-tryprophan is an essential amino acid that acts like a natural mood regulator that is necessary for normal growth in infants and for nitrogen balance in adults.",204.23,"73-22-3",{"v":11,"d":"11.00"},53.86,"N/A","N/A","http://selleckchem.com/products/l-tryptophan.html","C11H12N2O2","free base","N/A","NC(CC1=C[NH]C2=C1C=CC=C2)C(O)=O",-1.312,1,2,3]
["S3996","Thioctic acid","g3","L8000-11","in 10mM DMSO","Others","Others","Thioctic acid (DL-α-Lipoic acid) is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form., Thioctic acid (DL-α-Lipoic acid)是环状二硫抗氧化剂，可与其还原性二硫酚形式相互转换。",206.33,"1077-28-7",{"v":41,"d":"41.00"},198.71,"N/A","N/A","http://selleckchem.com/products/thioctic-acid.html","C8H14O2S2","free base","DL-α-Lipoic Acid","OC(=O)CCCCC1CCSS1",2.258,1,0,5]
["S3998","(+)-α-Lipoic acid","h3","L8000-11","in 10mM DMSO","LTR,NF-κB","NF-κB","(+)-α-Lipoic acid ((R)-(+)-α-Lipoic acid, α-Lipoic acid, Alpha-Lipoic acid), a physiological form of thioctic acid, is a strong antioxidant that relieves diabetic neuropathic symptoms. It shows superior antioxidative effects to its racemate. R(+)-α-lipoic acid is an essential cofactor of mitochondrial enzyme complexes. R(+)-α-lipoic acid inhibits NF-κB-dependent HIV-1 LTR activation.",206.33,"1200-22-2",{"v":41,"d":"41.00"},198.71,"N/A","N/A","http://selleckchem.com/products/alpha-lipoic-acid.html","C8H14O2S2","free base","(R)-(+)-α-Lipoic acid, α-Lipoic acid, Alpha-Lipoic acid","OC(=O)CCCCC1CCSS1",2.258,1,0,5]
["S4001","Cabozantinib malate","a4","L8000-11","in 10mM DMSO","Apoptosis related,Axl,c-Kit,c-Met,c-RET,FLT3,VEGFR","Protein Tyrosine Kinase","Cabozantinib malate (XL184) is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret (c-Ret), Kit (c-Kit), Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively. Cabozantinib malate (XL184) induces apoptosis.",635.59,"1140909-48-3",{"v":100,"d":"100.00"},157.33,"<1","N/A","http://selleckchem.com/products/cabozantinib-malate.html","C28H24FN3O5.C4H6O5","Malate","XL184","COC1=CC2=C(C=C1OC)C(=CC=N2)OC3=CC=C(NC(=O)C4(CC4)C(=O)NC5=CC=C(F)C=C5)C=C3.OC(CC(O)=O)C(O)=O",3.331,8,3,11]
["S4003","Lithocholic acid","b4","L8000-11","in 10mM DMSO","FXR","Metabolism","Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity, its toxic effect can be protected after it activates the vitamin D receptor, PXR and FXR.",376.57,"434-13-9",{"v":75,"d":"75.00"},199.17,"<1","N/A","http://selleckchem.com/products/lithocholic-acid.html","C24H40O3","free base","N/A","CC(CCC(O)=O)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C",5.184,1,1,4]
["S4004","Ethambutol 2HCl","c4","L8000-11","in 10mM DMSO","Bacterial","Microbiology","Ethambutol 2HCl (CL40881) is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.",277.23,"1070-11-7",{"v":56,"d":"56.00"},{"v":202,"d":"202.00"},{"v":56,"d":"56.00"},{"v":202,"d":"202.00"},"http://selleckchem.com/products/ethambutol-hcl.html","C10H24N2O2.2HCl","Dihydrochloride","CL40881","Cl.Cl.CCC(CO)NCCNC(CC)CO",0.874,0,4,9]
["S4007","Pentamidine isethionate","d4","L8000-11","in 10mM DMSO","phosphatase","Metabolism","Pentamidine is an inhibitor of PRL Phosphatases and also inhibits synthesis of DNA, RNA and protein.",592.68,"140-64-7",{"v":100,"d":"100.00"},168.73,{"v":100,"d":"100.00"},168.73,"http://selleckchem.com/products/pentamidine-isethionate.html","C19H24N4O2.2C2H6O4S","isethionate","N/A","NC(=N)C1=CC=C(OCCCCCOC2=CC=C(C=C2)C(N)=N)C=C1.OCC[S](O)(=O)=O.OCC[S](O)(=O)=O",0.751,2,4,14]
["S4009","Mirabegron","e4","L8000-11","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Mirabegron (YM 178) is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.",396.51,"223673-61-8",{"v":79,"d":"79.00"},199.24,"<1","N/A","http://selleckchem.com/products/mirabegron-ym178.html","C21H24N4O2S","free base","YM 178","NC1=NC(=CS1)CC(=O)NC2=CC=C(CCNCC(O)C3=CC=CC=C3)C=C2",{"v":2.26,"d":"2.260"},2,4,9]
["S4010","Acebutolol HCl","f4","L8000-11","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Acebutolol is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias.",372.89,"34381-68-5",{"v":75,"d":"75.00"},201.13,{"v":75,"d":"75.00"},201.13,"http://selleckchem.com/products/acebutolol-hcl.html","C18H28N2O4.HCl","Hydrochloride","N/A","Cl.CCCC(=O)NC1=CC(=C(OCC(O)CNC(C)C)C=C1)C(C)=O",1.997,3,3,10]
["S4011","Ampiroxicam","g4","L8000-11","in 10mM DMSO","COX","Neuronal Signaling","Ampiroxicam (CP 65703) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.",447.46,"99464-64-9",{"v":90,"d":"90.00"},201.14,"<1","N/A","http://selleckchem.com/products/ampiroxicam.html","C20H21N3O7S","free base","CP 65703","CCOC(=O)OC(C)OC1=C(N(C)[S](=O)(=O)C2=C1C=CC=C2)C(=O)NC3=NC=CC=C3",1.718,8,1,8]
["S4012","Desloratadine","h4","L8000-11","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Desloratadine (SCH-34117, NSC 675447) is a potent antagonist for  human histamine H1 receptor with IC50 of 51 nM.",310.82,"100643-71-8",{"v":26,"d":"26.00"},83.65,"<1","N/A","http://selleckchem.com/products/desloratadine.html","C19H19ClN2","free base","SCH-34117, NSC 675447","ClC1=CC2=C(C=C1)C(=C3CCNCC3)C4=C(CC2)C=CC=N4",4.213,1,1,0]
["S4014","Hyoscyamine","a5","L8000-11","in 10mM DMSO","AChR","Neuronal Signaling","Hyoscyamine (Daturine) is an AChR inhibitor with IC50 of 7.5 nM.",289.37,"101-31-5",{"v":58,"d":"58.00"},200.44,"<1","N/A","http://selleckchem.com/products/hyoscyamine-daturine.html","C17H23NO3","free base","Daturine","CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",1.721,2,1,5]
["S4017","Allylthiourea","b5","L8000-11","in 10mM DMSO","ROS","Immunology & Inflammation","Allylthiourea is a metabolic inhibitor that selective inhibits ammonia oxidation.",116.18,"109-57-9",{"v":23,"d":"23.00"},197.97,"<1","N/A","http://selleckchem.com/products/allylthiourea.html","C4H8N2S","free base","N/A","NC(=S)NCC=C",0.842,0,2,3]
["S4018","Sennoside B","c5","L8000-11","in 10mM DMSO","PDGFR","Protein Tyrosine Kinase","Sennoside B, a kind of irritant laxative isolated from rhei rhizome, inhibits PDGF-stimulated cell proliferation., Sennoside B，一种从大黄根茎中分离得到的刺激性泻药，抑制PDGF刺激的细胞增殖。",862.74,"128-57-4",{"v":100,"d":"100.00"},115.91,"<1","N/A","http://selleckchem.com/products/sennoside-b.html","C42H38O20","Free Base","N/A","OCC1OC(OC2=CC=CC3=C2C(=O)C4=C(O)C=C(C=C4C3C5C6=C(C(=O)C7=C(O)C=C(C=C57)C(O)=O)C(=CC=C6)OC8OC(CO)C(O)C(O)C8O)C(O)=O)C(O)C(O)C1O",0.409,8,10,9]
["S4019","Avanafil","d5","L8000-11","in 10mM DMSO","PDE","Metabolism","Avanafil is a highly selective PDE5 inhibitor with IC50 of 5.2 nM, >121-fold selectivity over other PDEs.",483.95,"330784-47-9",{"v":97,"d":"97.00"},200.43,"<1","N/A","http://selleckchem.com/products/avanafil.html","C23H26ClN7O3","free base","N/A","COC1=C(Cl)C=C(CNC2=C(C=NC(=N2)N3CCCC3CO)C(=O)NCC4=NC=CC=N4)C=C1",2.165,6,3,9]
["S4022","Probenecid","e5","L8000-11","in 10mM DMSO","Taste Receptor,TRP Channel","Transmembrane Transporters","Probenecid (Benemid) is a classical competitive inhibitor of organic anion transport, which is also a TRPV2 agonist and an inhibitor of TAS2R16. Probenecid is also a clinically used broad-spectrum Pannexin1 (Panx1) blocker.",285.36,"57-66-9",{"v":57,"d":"57.00"},199.75,"<1","N/A","http://selleckchem.com/products/probenecid-benemid.html","C13H19NO4S","free base","Benemid","CCCN(CCC)[S](=O)(=O)C1=CC=C(C=C1)C(O)=O",2.321,3,0,7]
["S4023","Procaine HCl","f5","L8000-11","in 10mM DMSO","AChR,NMDAR,Sodium Channel","Transmembrane Transporters","Procaine (Novocaine) is an inhibitor of sodium channel, NMDA receptor and nAChR with IC50 of 60 μM, 0.296 mM and 45.5 μM, which is also an inhibitor of 5-HT3 with KD of 1.7 μM.",272.77,"51-05-8",{"v":55,"d":"55.00"},201.64,{"v":55,"d":"55.00"},201.64,"http://selleckchem.com/products/procaine-novocaine-hcl.html","C13H20N2O2.HCl","HCl","Novocaine HCl","Cl.CCN(CC)CCOC(=O)C1=CC=C(N)C=C1",2.157,2,1,7]
["S4024","Homatropine Methylbromide","g5","L8000-11","in 10mM DMSO","AChR","Neuronal Signaling","Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.",370.28,"80-49-9",{"v":74,"d":"74.00"},199.85,{"v":74,"d":"74.00"},199.85,"http://selleckchem.com/products/homatropine-methylbromide.html","C17H24NO3.Br","quaternary-N bromide salt","N/A","[Br-].C[N+]1(C)C2CCC1CC(C2)OC(=O)C(O)C3=CC=CC=C3",-2.076,2,1,4]
["S4025","Homatropine Bromide","h5","L8000-11","in 10mM DMSO","AChR","Neuronal Signaling","Homatropine Bromide is an muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.",356.25,"51-56-9",{"v":71,"d":"71.00"},{"v":199.3,"d":"199.30"},{"v":71,"d":"71.00"},{"v":199.3,"d":"199.30"},"http://selleckchem.com/products/homatropine-bromide.html","C16H21NO3.HBr","quaternary-N bromide salt","N/A","Br.CN1C2CCC1CC(C2)OC(=O)C(O)C3=CC=CC=C3",2.188,2,1,4]
["S4026","Hydroxyzine 2HCl","a6","L8000-11","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Hydroxyzine is a histamine H1-receptor antagonist, inhibits binding of [3H]pyrilamine/[3H]desloratadine to human histamine H1 receptor with IC50 of 10 nM/19 nM.",447.83,"2192-20-3",{"v":90,"d":"90.00"},200.97,{"v":90,"d":"90.00"},200.97,"http://selleckchem.com/products/hydroxyzine-2hcl.html","C21H27ClN2O2.2HCl","dihydrochloride","N/A","Cl.Cl.OCCOCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3",4.231,1,1,8]
["S4034","Diphemanil Methylsulfate","b6","L8000-11","in 10mM DMSO","AChR","Neuronal Signaling","Diphemanil Methylsulfate is a quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors (mAchR).",389.51,"62-97-5",{"v":25,"d":"25.00"},64.18,{"v":28,"d":"28.00"},71.89,"http://selleckchem.com/products/diphemanil-methylsulfate.html","C20H24N.CH3O4S","Methylsulfate","N/A","CO[S]([O-])(=O)=O.C[N+]1(C)CC[C](CC1)=[C](C2=CC=CC=C2)C3=CC=CC=C3",0.038,1,0,3]
["S4037","Doxapram HCl","d6","L8000-11","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Doxapram HCl inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.",432.98,"7081-53-0",{"v":87,"d":"87.00"},200.93,{"v":25,"d":"25.00"},57.74,"http://selleckchem.com/products/doxapram-hcl.html","C24H30N2O2.HCl.H2O","HCl","N/A","O.Cl.CCN1CC(CCN2CCOCC2)C(C1=O)(C3=CC=CC=C3)C4=CC=CC=C4",3.218,2,0,6]
["S4039","Methazolamide","e6","L8000-11","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Methazolamide (CL 8490) is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively.",236.27,"554-57-4",{"v":47,"d":"47.00"},198.92,"<1","N/A","http://selleckchem.com/products/methazolamide.html","C5H8N4O3S2","free base","CL 8490","CN1N=C(SC1=NC(C)=O)[S](N)(=O)=O",{"v":0.03,"d":"0.030"},5,1,1]
["S4040","Norethindrone","f6","L8000-11","in 10mM DMSO","Others,0","Others","Norethindrone (Norethisterone) is a synthetic progestin, which mimic the actions of the endogenous ovarian hormone progesterone.",298.42,"68-22-4",{"v":60,"d":"60.00"},201.06,"<1","N/A","http://selleckchem.com/products/norethindrone-norethisterone.html","C20H26O2","free base","Norethisterone","CC12CCC3C(CCC4=CC(=O)CCC34)C1CCC2(O)C#C",4.315,1,0,0]
["S4041","Olsalazine Sodium","g6","L8000-11","in 10mM DMSO","Anti-infection","Microbiology","Olsalazine Sodium is an anti-inflammatory prodrug, which consists of two 5-ASA moieties linked by an azo bond.",{"v":346.2,"d":"346.20"},"6054-98-4",{"v":4,"d":"4.00"},11.55,{"v":41,"d":"41.00"},118.43,"http://selleckchem.com/products/olsalazine-sodium.html","C14H8N2O6.2Na","Disodium Salt","N/A","[Na+].[Na+].OC1=CC=C(C=C1C([O-])=O)N=NC2=CC=C(O)C(=C2)C([O-])=O",0.026,2,2,4]
["S4042","Nafcillin Sodium","h6","L8000-11","in 10mM DMSO","β-lactamase","Microbiology","Nafcillin sodium (CL 8491) reversibly inhibits β-lactamase with Kd of 33 mM.",454.47,"7177-50-6",{"v":91,"d":"91.00"},200.23,{"v":91,"d":"91.00"},200.23,"http://selleckchem.com/products/nafcillin-sodium.html","C21H21N2O5S.H2O.Na","sodium Salt","CL 8491","O.CCOC1=C(C(=O)NC2C3SC(C)(C)C(N3C2=O)C(=O)O[Na])C4=C(C=CC=C4)C=C1",2.213,5,1,6]
["S4045","Pheniramine Maleate","a7","L8000-11","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Pheniramine Maleate is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.",356.42,"132-20-7",{"v":71,"d":"71.00"},{"v":199.2,"d":"199.20"},{"v":71,"d":"71.00"},{"v":199.2,"d":"199.20"},"http://selleckchem.com/products/pheniramine-maleate.html","C16H20N2.C4H4O4","Maleate","N/A","CN(C)CCC(C1=CC=CC=C1)C2=NC=CC=C2.OC(=O)\\C=C/C(O)=O",0.036,3,0,7]
["S4046","Estradiol Cypionate","b7","L8000-11","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estradiol cypionate is the 17 β-cyclopentylpropinate ester of estradiol, which inhibits ET-1 synthesis via estrogen receptor.",396.56,"313-06-4",{"v":79,"d":"79.00"},199.21,"<1","N/A","http://selleckchem.com/products/estradiol-cypionate.html","C26H36O3","free base","N/A","CC12CCC3C(CCC4=CC(=CC=C34)O)C1CCC2OC(=O)CCC5CCCC5",6.589,2,1,5]
["S4047","Bisacodyl","c7","L8000-11","in 10mM DMSO","Others","Others","Bisacodyl (INN) is a stimulant laxative drug that works directly on the colon to produce a bowel movement.",361.39,"603-50-9",{"v":72,"d":"72.00"},199.23,"<1","N/A","http://selleckchem.com/products/bisacodyl.html","C22H19NO4","free base","N/A","CC(=O)OC1=CC=C(C=C1)C(C2=CC=C(OC(C)=O)C=C2)C3=CC=CC=N3",3.691,5,0,7]
["S4049","Valdecoxib","d7","L8000-11","in 10mM DMSO","COX","Neuronal Signaling","Valdecoxib is a potent and selective inhibitor of COX-2 with IC50 of 5 nM.",314.36,"181695-72-7",{"v":63,"d":"63.00"},200.41,"<1","N/A","http://selleckchem.com/products/valdecoxib.html","C16H14N2O3S","free base","N/A","CC1=C(C2=CC=C(C=C2)[S](N)(=O)=O)C(=NO1)C3=CC=CC=C3",{"v":2.6,"d":"2.600"},4,1,3]
["S4051","Nabumetone","e7","L8000-11","in 10mM DMSO","COX","Neuronal Signaling","Nabumetone (BRL-14777) is a non-steroidal anti-inflammatory drug and its active metabolite inhibits the COX.",228.29,"42924-53-8",{"v":46,"d":"46.00"},{"v":201.5,"d":"201.50"},"<1","N/A","http://selleckchem.com/products/nabumetone.html","C15H16O2","free base","BRL-14777","COC1=CC=C2C=C(CCC(C)=O)C=CC2=C1",2.943,2,0,4]
["S4053","Sertraline HCl","f7","L8000-11","in 10mM DMSO","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Sertraline HCl (CP-51974-1) is a 5-HT antagonist with Ki of 13 nM.",342.69,"79559-97-0",{"v":69,"d":"69.00"},201.35,"<1","N/A","http://selleckchem.com/products/sertraline-hcl.html","C17H17Cl2N.HCl","HCl","CP-51974-1 HCl","Cl.CNC1CCC(C2=CC=C(Cl)C(=C2)Cl)C3=C1C=CC=C3",5.378,0,1,2]
["S4054","Spironolactone","g7","L8000-11","in 10mM DMSO","Androgen Receptor","Endocrinology & Hormones","Spironolactone is a potent antagonist of the androgen receptor with IC50 of 77 nM.",416.57,"52-01-7",{"v":83,"d":"83.00"},199.25,"<1","N/A","http://selleckchem.com/products/spironolactone.html","C24H32O4S","free base","N/A","CC(=O)SC1CC2=CC(=O)CCC2(C)C3CCC4(C)C(CCC45CCC(=O)O5)C13",3.731,4,0,2]
["S4059","Sodium Nitroprusside Dihydrate","h7","L8000-11","in 10mM DMSO","Others","Others","Sodium Nitroprusside  Dihydrate is a potent vasodilator working through releasing NO spontaneously in blood.",297.95,"13755-38-9",{"v":60,"d":"60.00"},201.38,{"v":60,"d":"60.00"},201.38,"http://selleckchem.com/products/sodium-nitroprusside-dihydrate.html","C5H4FeN6Na2O3","Dihydrate","N/A","[Na+].[Na+].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N",0.571,1,0,1]
["S4065","Guanabenz Acetate","b8","L8000-11","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Guanabenz Acetate (WY-8678) is an selective agonist of α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor with pEC50 of 8.25, 7.01 and ~5, respectively.",291.13,"23256-50-0",{"v":58,"d":"58.00"},199.22,"<1","N/A","http://selleckchem.com/products/guanabenz-wy-8678-acetate.html","C8H8Cl2N4.C2H4O2","Acetate","WY-8678 Acetate","CC(O)=O.NC(=N)N/N=C/C1=C(Cl)C=CC=C1Cl",1.987,2,2,3]
["S4070","Guanidine HCl","c8","L8000-11","in 10mM DMSO","Others","Others","Guanidine HCl (Aminoformamidine), the crystalline compound of strong alkalinity formed by the oxidation of guanine, is a normal product of protein metabolism and a protein denaturant.",95.53,"50-01-1",{"v":19,"d":"19.00"},198.89,{"v":19,"d":"19.00"},198.89,"http://selleckchem.com/products/guanidine-aminoformamidine-hcl.html","CH5N3.HCl","Hydrochloride","Aminoformamidine HCl","Cl.NC(N)=N",-0.606,0,2,0]
["S4071","Griseofulvin","d8","L8000-11","in 10mM DMSO","Microtubule Associated","Cytoskeletal Signaling","Griseofulvin, a production from some strains of the mold Penicillium griseofulvumam, is able to inhibit cell mitosis by interfering with microtubule function.",352.77,"126-07-8",{"v":50,"d":"50.00"},141.74,"<1","N/A","http://selleckchem.com/products/griseofulvin.html","C17H17ClO6","free base","N/A","COC1=CC(=C2C(=O)C3(OC2=C1Cl)C(C)CC(=O)C=C3OC)OC",2.495,6,0,3]
["S4072","Decamethonium Bromide","e8","L8000-11","in 10mM DMSO","AChR","Neuronal Signaling","Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent.",418.29,"541-22-0",{"v":34,"d":"34.00"},81.28,{"v":84,"d":"84.00"},200.82,"http://selleckchem.com/products/decamethonium-bromide.html","C16H38N2.2Br","Bromide","N/A","[Br-].[Br-].C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C",-3.707,0,0,11]
["S4073","Sodium 4-Aminosalicylate","f8","L8000-11","in 10mM DMSO","NF-κB","NF-κB","Sodium 4-Aminosalicylate is an antibiotic used to treat tuberculosis via NF-κB inhibition and free radical scavenging.",211.15,"6018-19-5",{"v":42,"d":"42.00"},198.91,{"v":42,"d":"42.00"},198.91,"http://selleckchem.com/products/aminosalicylate-sodium.html","C7H7NO3.2H2O.Na","Sodium Salt","N/A","[Na+].NC1=CC(=C(C=C1)C([O-])=O)O",-1.003,0,2,1]
["S4075","Zinc Pyrithione","g8","L8000-11","in 10mM DMSO","Fungal,Proton Pump","Transmembrane Transporters","Zinc pyrithione (OM-1563) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.",{"v":317.7,"d":"317.70"},"13463-41-7",{"v":30,"d":"30.00"},94.43,"<1","N/A","http://selleckchem.com/products/zinc-pyrithione.html","C10H8N2O2S2Zn","free base","OM-1563","O1N2C=CC=CC2=[SH][Zn]13ON4C=CC=CC4=[SH]3",0.874,2,0,0]
["S4076","Propranolol HCl","h8","L8000-11","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Propranolol HCl (AY-64043, ICI-45520, NCS-91523) is a competitive non-selective beta-adrenergic receptors inhibitor.",{"v":295.8,"d":"295.80"},"318-98-9",{"v":59,"d":"59.00"},199.46,{"v":6,"d":"6.00"},20.28,"http://selleckchem.com/products/propranolol-hcl.html","C16H21NO2.HCl","Hydrochloride","AY-64043, ICI-45520, NCS-91523","Cl.CC(C)NCC(O)COC1=CC=CC2=CC=CC=C12",2.922,1,2,6]
["S4078","Mefenamic Acid","a9","L8000-11","in 10mM DMSO","COX","Neuronal Signaling","Mefenamic Acid (CI 473, CN-35355) is a competitive inhibitor of COX-1 and COX-2.",241.29,"61-68-7",{"v":48,"d":"48.00"},198.93,"<1","N/A","http://selleckchem.com/products/mefenamic-acid.html","C15H15NO2","free base","CI 473, CN-35355","CC1=C(C)C(=CC=C1)NC2=CC=CC=C2C(O)=O",3.982,1,1,3]
["S4079","Ticagrelor","b9","L8000-11","in 10mM DMSO","P2 Receptor","Neuronal Signaling","Ticagrelor (AZD 6140, AR-C 126532XX) is the first reversibly binding oral P2Y12 receptor antagonist with Ki of 2 nM.",522.57,"274693-27-5",{"v":100,"d":"100.00"},191.36,"<1","N/A","http://selleckchem.com/products/ticagrelor.html","C23H28F2N6O4S","free base","AZD 6140, AR-C 126532XX","CCCSC1=NC2=C(N=N[N]2C3CC(OCCO)C(O)C3O)C(=N1)NC4CC4C5=CC(=C(F)C=C5)F",2.843,5,4,10]
["S4080","Triamterene","c9","L8000-11","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Triamterene (SKF8542) blocks epithelial Na+ channel (ENaC) in a voltage-dependent manner with IC50 of 4.5 μM.",253.26,"396-01-0",{"v":20,"d":"20.00"},78.97,"<1","N/A","http://selleckchem.com/products/triamterene.html","C12H11N7","free base","SKF8542","NC1=NC2=C(N=C(C3=CC=CC=C3)C(=N2)N)C(=N1)N",1.017,4,3,1]
["S4081","Sulfacetamide Sodium","d9","L8000-11","in 10mM DMSO","Anti-infection,Autophagy","Immunology & Inflammation","Sulfacetamide Sodium is an anti-biotic.",236.22,"127-56-0",{"v":19,"d":"19.00"},80.43,{"v":51,"d":"51.00"},{"v":215.9,"d":"215.90"},"http://selleckchem.com/products/sulfacetamide-sodium.html","C8H10N2O3S.Na","Sodium Salt","N/A","[Na+].CC(=O)[N-][S](=O)(=O)C1=CC=C(N)C=C1",-0.118,3,1,2]
["S4082","Spiramycin","e9","L8000-11","in 10mM DMSO","Antibiotics","Microbiology","Spiramycin (Formacidine) is a 16-membered ring macrolide (antibiotic).",843.05,"8025-81-8",{"v":100,"d":"100.00"},118.62,"<1","N/A","http://selleckchem.com/products/spiramycin.html","C43H74N2O14","free base","Formacidine","COC1C(O)CC(=O)OC(C)C/C=C/C=C/C(OC2CCC(C(C)O2)N(C)C)C(C)CC(CC=O)C1OC3OC(C)C(OC4CC(C)(O)C(O)C(C)O4)C(C3O)N(C)C",2.049,10,3,11]
["S4083","Vitamin A Acetate","f9","L8000-11","in 10mM DMSO","Vitamin","Metabolism","Vitamin A Acetate (Retinyl, Retinol) is a group of unsaturated nutritional hydrocarbons, that includes retinol, retinal, retinoic acid, and several provitamin A carotenoids, among which beta-carotene is the most important.",328.49,"127-47-9",{"v":65,"d":"65.00"},197.88,"<1","N/A","http://selleckchem.com/products/vitamin-a-acetate.html","C22H32O2","free base","Retinyl (Retinol) Acetate","CC(=O)OC/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C",5.695,2,0,7]
["S4086","Loxapine Succinate","g9","L8000-11","in 10mM DMSO","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Loxapine Succinate(NSC 759578) is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent.",{"v":445.9,"d":"445.90"},"27833-64-3",{"v":89,"d":"89.00"},{"v":199.6,"d":"199.60"},"<1","N/A","http://selleckchem.com/products/loxapine-succinate.html","C18H18ClN3O.C4H6O4","Succinate","NSC 759578","CN1CCN(CC1)C2=NC3=C(OC4=C2C=C(Cl)C=C4)C=CC=C3.OC(=O)CCC(O)=O",0.039,4,0,4]
["S4088","Flumethasone","h9","L8000-11","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Flumethasone (RS-2177, NSC-54702,Flumetasone) is a glucocorticoid receptor agonist, this complex binds to the nucleus causing a variety of genetic activation and repressions.",410.45,"2135-17-3",{"v":82,"d":"82.00"},199.78,"<1","N/A","http://selleckchem.com/products/flumethasone.html","C22H28F2O5","free base","RS-2177, NSC-54702,Flumetasone","CC1CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO",1.546,2,2,2]
["S4089","Halobetasol Propionate","a10","L8000-11","in 10mM DMSO","Phospholipase (e.g. PLA)","Metabolism","Halobetasol Propionate (BMY-30056, CGP-14458,Ulobetasol propionate) is an anti-inflammatory and a dermatologic agent commonly used to treat psoriasis. Halobetasol propionate is thought to act by the induction of phospholipase A2 (PLA2) inhibitory proteins.",484.96,"66852-54-8",{"v":97,"d":"97.00"},200.02,"<1","N/A","http://selleckchem.com/products/halobetasol-propionate.html","C25H31ClF2O5","free base","BMY-30056, CGP-14458,Ulobetasol propionate","CCC(=O)OC1(C(C)CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)CCl",3.797,4,1,5]
["S4090","Fenspiride HCl","b10","L8000-11","in 10mM DMSO","PDE","Metabolism","Fenspiride(Decaspiride) is a bronchodilator with anti-inflammatory properties, inhibiting phosphodiesterase 4 and phosphodiesterase 3 activities with logIC50 values of 4.16 and 3.44, respectively, in human isolated bronchi.",296.79,"5053-08-7",{"v":9,"d":"9.00"},30.32,{"v":59,"d":"59.00"},198.79,"http://selleckchem.com/products/Fenspiride-hcl.html","C15H20N2O2.HCl","Hydrochloride","Decaspiride","Cl.O=C1NCC2(CCN(CCC3=CC=CC=C3)CC2)O1",2.089,2,1,3]
["S4095","Difluprednate","c10","L8000-11","in 10mM DMSO","Others","Others","Difluprednate (difluoroprednisolone butyrate acetate, DFBA, CM 9155) is a synthetic difluorinated prednisolone derivative, it is originally developed for dermatologic applications.",508.55,"23674-86-4",{"v":100,"d":"100.00"},196.64,"<1","N/A","http://selleckchem.com/products/difluprednate.html","C27H34F2O7","free base","CM 9155","CCCC(=O)OC1(CCC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)COC(C)=O",3.108,6,1,8]
["S4098","Halcinonide","d10","L8000-11","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Halcinonide(SQ-18566) is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent.",454.96,"3093-35-4",{"v":90,"d":"90.00"},197.82,"<1","N/A","http://selleckchem.com/products/halcinonide.html","C24H32ClFO5","free base","SQ-18566","CC1(C)OC2CC3C4CCC5=CC(=O)CCC5(C)C4(F)C(O)CC3(C)C2(O1)C(=O)CCl",2.384,4,1,2]
["S4101","Voglibose","e10","L8000-11","in 10mM DMSO","Carbohydrate Metabolism","Metabolism","Voglibose (AO 128) is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various disorders caused by hyperglycemia.",267.28,"83480-29-9",{"v":74,"d":"74.00"},276.86,{"v":74,"d":"74.00"},276.86,"http://selleckchem.com/products/voglibose.html","C10H21NO7","free base","AO 128","OCC(CO)NC1CC(O)(CO)C(O)C(O)C1O",-4.083,0,7,5]
["S4102","Eprosartan Mesylate","f10","L8000-11","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Eprosartan(SKF-108566J) is a nonpeptide angiotensin II receptor antagonist, [3H]-eprosartan binds to the AT1 receptor with KD of 0.83 nM in rat vascular smooth muscle cells.",520.62,"144143-96-4",{"v":104,"d":"104.00"},199.76,"<1","N/A","http://selleckchem.com/products/eprosartan-mesylate.html","C23H24N2O4S.CH4O3S","Mesylate","SKF-108566J","CCCCC1=NC=C(\\C=C(CC2=CC=CS2)\\C(O)=O)[N]1CC3=CC=C(C=C3)C(O)=O.C[S](O)(=O)=O",4.418,3,0,10]
["S4104","Diminazene Aceturate","g10","L8000-11","in 10mM DMSO","ACE,Parasite","Microbiology","Diminazene(Diminazene diaceturate) is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent.  The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties.",515.52,"908-54-3",{"v":19,"d":"19.00"},36.86,{"v":100,"d":"100.00"},193.98,"http://selleckchem.com/products/diminazene-aceturate.html","C14H15N7.2C4H7NO3","Aceturate","Diminazene diaceturate","CC(=O)NCC(O)=O.CC(=O)NCC(O)=O.NC(=N)C1=CC=C(NN=NC2=CC=C(C=C2)C(N)=N)C=C1",-0.592,6,5,9]
["S4107","Clofazimine","h10","L8000-11","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,Dyes,Phospholipase (e.g. PLA)","Metabolism","Clofazimine (NSC-141046) is a rhimophenazine dye, originally developed for the treatment of tuberculosis, it has both antimicrobial and antiinflammatory activity, postulated mechanisms of action include intercalation of clofazimine with bacterial DNA and increasing levels of cellular phospholipase A2.",{"v":473.4,"d":"473.40"},"2030-63-9",{"v":5,"d":"5.00"},10.56,"<1","N/A","http://selleckchem.com/products/clofazimine.html","C27H22Cl2N4","free base","NSC-141046","CC(C)N=C1C=C2N(C3=CC=C(Cl)C=C3)C4=C(C=CC=C4)N=C2C=C1NC5=CC=C(Cl)C=C5",7.137,2,1,4]
["S4110","Estradiol Benzoate","a11","L8000-11","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estradiol benzoate(β-Estradiol 3-benzoate) is an estradiol analog which binds to the human, murine and chicken ERα with IC50 of 22-28 nM.",376.49,"50-50-0",{"v":75,"d":"75.00"},199.21,"<1","N/A","http://selleckchem.com/products/estradiol-benzoate.html","C25H28O3","free base","β-Estradiol 3-benzoate","CC12CCC3C(CCC4=CC(=CC=C34)OC(=O)C5=CC=CC=C5)C1CCC2O",5.512,2,1,3]
["S4113","Desvenlafaxine","b11","L8000-11","in 10mM DMSO","Adrenergic Receptor,Serotonin Transporter","Neuronal Signaling","Desvenlafaxine (WY 45233 Succinate) is a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with Ki of 40.2 nM and 558.4 nM, respectively.",263.38,"93413-62-8",{"v":37,"d":"37.00"},140.48,"<1","N/A","http://selleckchem.com/products/desvenlafaxine.html","C16H25NO2","Free Base","WY 45233  Succinate","CN(C)CC(C1=CC=C(O)C=C1)C2(O)CCCCC2",2.796,0,1,4]
["S4114","Triclabendazole","c11","L8000-11","in 10mM DMSO","Microtubule Associated","Cytoskeletal Signaling","Triclabendazole (CGA-89317,tcbz) is a benzimidazole, it binds to tubulin impairing intracellular transport mechanisms and interferes with protein synthesis.",359.66,"68786-66-3",{"v":72,"d":"72.00"},200.19,"<1","N/A","http://selleckchem.com/products/triclabendazole.html","C14H9Cl3N2OS","free base","CGA-89317,tcbz","CSC1=NC2=C([NH]1)C=C(Cl)C(=C2)OC3=C(Cl)C(=CC=C3)Cl",5.982,2,1,3]
["S4118","Histamine 2HCl","d11","L8000-11","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Histamine(Ceplene) is an organic nitrogen compound, acts on target cells in mammalian brain via stimulation of Histamine 1/2.",184.07,"56-92-8",{"v":3,"d":"3.00"},{"v":16.3,"d":"16.30"},{"v":37,"d":"37.00"},201.01,"http://selleckchem.com/products/histamine-2hcl.html","C5H9N3.2HCl","Dihydrochloride","Ceplene","Cl.Cl.NCCC1=C[NH]C=N1",{"v":0.05,"d":"0.050"},1,2,2]
["S4119","Pefloxacin Mesylate Dihydrate","e11","L8000-11","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Pefloxacin Mesylate Dihydrate (1589 RB,Pefloxacinium mesylate dihydrate) is the third generation of fluoroquinolone class of antibacterials, which inhibits Topoisomerase II activity and DNA replication.",465.49,"149676-40-4",{"v":9,"d":"9.00"},19.33,{"v":67,"d":"67.00"},143.93,"http://selleckchem.com/products/pefloxacin-mesylate-dihydrate.html","C17H20FN3O3.CH4O3S.2H2O","Mesylate","1589 RB,Pefloxacinium mesylate dihydrate","O.O.CCN1C=C(C(O)=O)C(=O)C2=C1C=C(N3CCN(C)CC3)C(=C2)F.C[S](O)(=O)=O",-2.033,2,0,3]
["S4120","Sulconazole Nitrate","f11","L8000-11","in 10mM DMSO","Fungal","Microbiology","Sulconazole Nitrate(Exelderm,RS 44872) is an imidazole derivative with broad-spectrum antifungal activity.",460.76,"61318-91-0",{"v":92,"d":"92.00"},199.67,"<1","N/A","http://selleckchem.com/products/sulconazole-nitrate.html","C18H15Cl3N2S.HNO3","Nitrate","Exelderm,RS 44872","O[N+]([O-])=O.ClC1=CC=C(CSC(C[N]2C=CN=C2)C3=CC=C(Cl)C=C3Cl)C=C1",4.467,1,0,6]
["S4123","Timolol Maleate","g11","L8000-11","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Timolol Maleate (MK-950,(S)-Timolol Maleate) is a non-selective, beta-adrenergic receptor antagonist for β1/β2 with Ki of 1.97 nM/2.0 nM.",432.49,"26921-17-5",{"v":86,"d":"86.00"},198.85,"<1","N/A","http://selleckchem.com/products/timolol-maleate.html","C13H24N4O3S.C4H4O4","Maleate","MK-950,(S)-Timolol Maleate","CC(C)(C)NCC(O)COC1=NSN=C1N2CCOCC2.OC(=O)\\C=C/C(O)=O",-1.539,6,2,9]
["S4124","Tolazoline HCl","h11","L8000-11","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Tolazoline(Imidaline hydrochloride,NSC35110 hydrochloride) is a non-selective competitive α-adrenergic receptor antagonist.",196.68,"59-97-2",{"v":39,"d":"39.00"},198.29,{"v":39,"d":"39.00"},198.29,"http://selleckchem.com/products/tolazoline-hcl.html","C10H12N2.HCl","Hydrochloride","Imidaline hydrochloride,NSC35110 hydrochloride","Cl.C1CN=C(CC2=CC=CC=C2)N1",1.533,1,1,2]
["S4125","Sodium Phenylbutyrate","a2","L8000-12","in 10mM DMSO","HDAC","DNA Damage/DNA Repair","Sodium phenylbutyrate (4-PBA, 4-Phenylbutyric acid, NaPB) is a salt of 4-phenylbutyrate (4-PBA) or 4-phenylbutyric acid.Sodium phenylbutyrate is a histone deacetylase inhibitor, used to treat urea cycle disorders.",187.19,"1716-12-7",{"v":8,"d":"8.00"},42.97,{"v":30,"d":"30.00"},161.13,"http://selleckchem.com/products/sodium-phenylbutyrate.html","C10H11O2.Na","Sodium Salt","4-PBA, 4-Phenylbutyric acid, NaPB","[Na]OC(=O)CCCC1=CC=CC=C1",2.497,2,0,5]
["S4131","Levodropropizine","b2","L8000-12","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Levodropropizine((S)-(-)-Dropropizine,DF-526) possess anti-allergic and inhibits histamine receptor, reduces cough by interfering with stimulus activation of peripheral endings of sensory nerves and by modulation of neuropeptides involved in the cough reflex.",236.31,"99291-25-5",{"v":47,"d":"47.00"},198.89,{"v":15,"d":"15.00"},63.48,"http://selleckchem.com/products/levodropropizine.html","C13H20N2O2","free base","(S)-(-)-Dropropizine,DF-526","OCC(O)CN1CCN(CC1)C2=CC=CC=C2",0.899,0,2,4]
["S4135","Clorprenaline HCl","c2","L8000-12","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Clorprenaline HCl (NSC 334693) is a β2-receptor agonist, it has a significant expansion of the bronchial effect.",250.16,"6933-90-0",{"v":50,"d":"50.00"},199.87,{"v":50,"d":"50.00"},199.87,"http://selleckchem.com/products/clorprenaline-hcl.html","C11H16ClNO.HCl","Hydrochloride","NSC 334693","Cl.CC(C)NCC(O)C1=CC=CC=C1Cl",2.629,0,2,4]
["S4136","Carprofen","d2","L8000-12","in 10mM DMSO","COX","Neuronal Signaling","Carprofen inhibits canine COX2 with IC50 of 30 nM.",273.71,"53716-49-7",{"v":55,"d":"55.00"},200.94,"<1","N/A","http://selleckchem.com/products/carprofen.html","C15H12ClNO2","free base","N/A","CC(C(O)=O)C1=CC2=C(C=C1)C3=C([NH]2)C=CC(=C3)Cl",4.114,1,1,2]
["S4147","Azithromycin Dihydrate","e2","L8000-12","in 10mM DMSO","Anti-infection","Microbiology","Azithromycin Dihydrate(CP-62993 dihydrate) is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin.",785.02,"117772-70-0",{"v":100,"d":"100.00"},127.39,{"v":10,"d":"10.00"},12.74,"http://selleckchem.com/products/azithromycin-dihydrate.html","C38H72N2O12.2H2O","free base","CP-62993 dihydrate","O.O.CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)CN(C)C(C)C(O)C1(C)O",1.663,7,3,7]
["S4149","Amfenac Sodium Monohydrate","f2","L8000-12","in 10mM DMSO","COX","Neuronal Signaling","Amfenac Sodium monohydrate is a non-steroidal analgesic anti-inflammatory drug with acetic acid moiety. The IC50 values for COX1 and COX2 is 250 nM and 150 nM, respectively.",295.27,"61618-27-7",{"v":59,"d":"59.00"},199.82,{"v":59,"d":"59.00"},199.82,"http://selleckchem.com/products/amfenac-sodium-monohydrate.html","C15H12NO3.H2O.Na","free base","N/A","O.[Na+].NC1=C(C=CC=C1CC([O-])=O)C(=O)C2=CC=CC=C2",{"v":0.47,"d":"0.470"},1,1,4]
["S4151","Penfluridol","g2","L8000-12","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Penfluridol (TLP-607,R-16341) is a highly potent, first generation diphenylbutylpiperidine antipsychotic.",523.97,"26864-56-2",{"v":100,"d":"100.00"},190.85,"<1","N/A","http://selleckchem.com/products/penfluridol.html","C28H27ClF5NO","free base","TLP-607,R-16341","OC1(CCN(CCCC(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3)CC1)C4=CC(=C(Cl)C=C4)C(F)(F)F",7.311,0,0,8]
["S4152","Ethamsylate","h2","L8000-12","in 10mM DMSO","Prostaglandin Receptor","GPCR & G Protein","Ethamsylate (Etamsylate) is a haemostatic drug, which inhibits biosynthesis and action of prostaglandins, and increases capillary endothelial resistance as and platelet adhesion.",263.31,"2624-44-4",{"v":53,"d":"53.00"},201.28,{"v":53,"d":"53.00"},201.28,"http://selleckchem.com/products/ethamsylate.html","C6H6O5S.C4H11N","Diethylamine","Etamsylate","CCNCC.OC1=CC=C(O)C(=C1)[S](O)(=O)=O",{"v":1.16,"d":"1.160"},0,3,3]
["S4155","Chlorzoxazone","a3","L8000-12","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Chlorzoxazone(Chlorzoxazon,Paraflex) is a muscle-relaxing drug,and a probe for human liver cytochrome P-450IIE1.",169.57,"95-25-0",{"v":34,"d":"34.00"},200.51,"<1","N/A","http://selleckchem.com/products/chlorzoxazone.html","C7H4ClNO2","free base","Chlorzoxazon,Paraflex","ClC1=CC2=C(OC(=O)N2)C=C1",2.004,2,1,0]
["S4159","Bezafibrate","b3","L8000-12","in 10mM DMSO","PPAR","Metabolism","Bezafibrate (BM 15075) is the first clinically tested dual and pan-PPAR co-agonism.",361.82,"41859-67-0",{"v":72,"d":"72.00"},198.99,"<1","N/A","http://selleckchem.com/products/bezafibrate.html","C19H20ClNO4","free base","BM 15075","CC(C)(OC1=CC=C(CCNC(=O)C2=CC=C(Cl)C=C2)C=C1)C(O)=O",3.868,3,1,7]
["S4160","Penicillin G Sodium","c3","L8000-12","in 10mM DMSO","Antibiotics,Antibiotics for Mammalian Cell Culture,Antibiotics for Plant Cell Culture","Microbiology","Penicillin G Sodium (Benzylpenicillin) is a β-lactam antibiotic produced by Penicillin spp.",356.37,"69-57-8",{"v":71,"d":"71.00"},199.23,{"v":71,"d":"71.00"},199.23,"http://selleckchem.com/products/benzylpenicillin-sodium.html","C16H18N2O4S.Na","Sodium Salt","Benzylpenicillin Sodium","[Na+].CC1(C)SC2C(NC(=O)CC3=CC=CC=C3)C(=O)N2C1C([O-])=O",{"v":-0.35,"d":"-0.350"},2,1,4]
["S4162","Benzethonium Chloride","d3","L8000-12","in 10mM DMSO","AChR","Neuronal Signaling","Benzethonium chloride is a potent inhibitor of nAChRs, it inhibits α4β2 nAChRs and α7 nAChRs with IC50 of 49 nM and 122 nM, respectively.",448.08,"121-54-0",{"v":90,"d":"90.00"},200.86,{"v":90,"d":"90.00"},200.86,"http://selleckchem.com/products/benzethonium-chloride.html","C27H42NO2.Cl","Chloride","N/A","[Cl-].CC(C)(C)CC(C)(C)C1=CC=C(OCCOCC[N+](C)(C)CC2=CC=CC=C2)C=C1",2.147,2,0,12]
["S4164","Doxofylline","e3","L8000-12","in 10mM DMSO","PDE","Metabolism","Doxofylline (Doxophylline) is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma.",266.25,"69975-86-6",{"v":53,"d":"53.00"},199.06,{"v":24,"d":"24.00"},90.14,"http://selleckchem.com/products/doxofylline.html","C11H14N4O4","free base","Doxophylline","CN1C(=O)N(C)C2=C([N](CC3OCCO3)C=N2)C1=O",-0.344,5,0,2]
["S4165","Benzydamine HCl","f3","L8000-12","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Benzydamine HCl (AF864) is a topical nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, antipyretic and local anesthetic activity.",345.87,"132-69-4",{"v":69,"d":"69.00"},{"v":199.5,"d":"199.50"},{"v":69,"d":"69.00"},{"v":199.5,"d":"199.50"},"http://selleckchem.com/products/benzydamine-hcl.html","C19H23N3O.HCl","Hydrochloride","AF864","Cl.CN(C)CCCOC1=N[N](CC2=CC=CC=C2)C3=CC=CC=C13",4.368,2,0,7]
["S4166","Chlorpropamide","g3","L8000-12","in 10mM DMSO","ATPase","Transmembrane Transporters","Chlorpropamide inhibits Na(+),K(+)-ATPase and stimulates a high affinity cyclic AMP-phosphodiesterase of isolated liver plasma membrane. Chlorpropamide is a sulfonylurea class drug for type 2 diabetes mellitus.",276.74,"94-20-2",{"v":55,"d":"55.00"},198.74,"<1","N/A","http://selleckchem.com/products/chlorpropamide.html","C10H13ClN2O3S","free base","N/A","CCCNC(=O)N[S](=O)(=O)C1=CC=C(Cl)C=C1",2.058,3,2,4]
["S4167","Cyromazine","h3","L8000-12","in 10mM DMSO","Parasite","Microbiology","Cyromazine(Cyromazin,CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide.",166.18,"66215-27-8",{"v":33,"d":"33.00"},198.58,{"v":1,"d":"1.00"},6.02,"http://selleckchem.com/products/cyromazine.html","C6H10N6","free base","Cyromazin,CGA-72662","NC1=NC(=NC(=N1)N)NC2CC2",0.313,3,3,2]
["S4169","Teriflunomide","a4","L8000-12","in 10mM DMSO","Dehydrogenase,Immunology & Inflammation related","Metabolism","Teriflunomide (A77 1726, HMR-1726) is the active metabolite of leflunomide, inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase, used as an immunomodulatory agent.",270.21,"163451-81-8",{"v":32,"d":"32.00"},118.43,"<1","N/A","http://selleckchem.com/products/teriflunomide.html","C12H9F3N2O2","free base","A77 1726, HMR-1726","C/C(O)=C(C#N)/C(=O)NC1=CC=C(C=C1)C(F)(F)F",2.091,1,2,3]
["S4170","Coumarin","b4","L8000-12","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Coumarin is a secondary phytochemical with hepatotoxic and carcinogenic properties.",146.14,"91-64-5",{"v":29,"d":"29.00"},198.44,"<1","N/A","http://selleckchem.com/products/coumarin.html","C9H6O2","free base","N/A","O=C1OC2=C(C=CC=C2)C=C1",1.899,2,0,0]
["S4171","Choline Chloride","c4","L8000-12","in 10mM DMSO","AChR","Neuronal Signaling","Choline chloride(Hepacholine) is a quaternary ammonium salt used as an additive for animal feed. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.",139.62,"67-48-1",{"v":28,"d":"28.00"},200.54,{"v":28,"d":"28.00"},200.54,"http://selleckchem.com/products/choline-chloride.html","C5H14NO.Cl","Chloride","Hepacholine","[Cl-].C[N+](C)(C)CCO",-4.248,0,1,2]
["S4172","Cetylpyridinium Chloride","d4","L8000-12","in 10mM DMSO","Anti-infection","Microbiology","Cetylpyridinium chloride(CPC) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.",339.99,"123-03-5",{"v":68,"d":"68.00"},200.01,{"v":68,"d":"68.00"},200.01,"http://selleckchem.com/products/cetylpyridinium-chloride.html","C21H38N.Cl","Chloride","CPC","[Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1",5.563,0,0,15]
["S4175","Sulfaguanidine","e4","L8000-12","in 10mM DMSO","Anti-infection","Microbiology","Sulfaguanidine is a sulfonamide used as an anti-infective agent.",214.24,"57-67-0",{"v":43,"d":"43.00"},200.71,"<1","N/A","http://selleckchem.com/products/sulfaguanidine.html","C7H10N4O2S","free base","N/A","NC(=N)N[S](=O)(=O)C1=CC=C(N)C=C1",-0.377,2,3,3]
["S4177","Uracil","f4","L8000-12","in 10mM DMSO","Others","Others","Uracil is one of the four nucleobases in the nucleic acid of RNA can be used for drug delivery and as a pharmaceutical.",112.09,"66-22-8",{"v":22,"d":"22.00"},196.27,"<1","N/A","http://selleckchem.com/products/uracil.html","C4H4N2O2","free base","N/A","O=C1NC=CC(=O)N1",-1.012,2,2,0]
["S4181","Nicardipine HCl","g4","L8000-12","in 10mM DMSO","ADC Cytotoxin,Calcium Channel","Transmembrane Transporters","Nicardipine HCl (RS-69216,YC-93) is a dihydropyridine calcium-channel blocking agent used for the treatment of vascular disorders.",515.99,"54527-84-3",{"v":100,"d":"100.00"},{"v":193.8,"d":"193.80"},"<1","N/A","http://selleckchem.com/products/nicardipine-hcl.html","C26H29N3O6.HCl","Hydrochloride","RS-69216,YC-93","Cl.COC(=O)C1=C(C)NC(=C(C1C2=CC(=CC=C2)[N+]([O-])=O)C(=O)OCCN(C)CC3=CC=CC=C3)C",{"v":3.87,"d":"3.870"},4,1,11]
["S4182","Nifuroxazide","h4","L8000-12","in 10mM DMSO","STAT","JAK/STAT","Nifuroxazide is a cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcription activity with IC50 of 3 μM against IL-6-induced STAT3 activation in U3A cells.",275.22,"965-52-6",{"v":55,"d":"55.00"},199.84,"<1","N/A","http://selleckchem.com/products/nifuroxazide.html","C12H9N3O5","free base","N/A","OC1=CC=C(C=C1)C(=O)N/N=C/C2=CC=C(O2)[N+]([O-])=O",1.855,3,2,4]
["S4184","Penciclovir","a5","L8000-12","in 10mM DMSO","Antiviral","Microbiology","Penciclovir (BRL-39123, VSA 671,NSC-759624) is a purine acyclic nucleoside analogue with potent antiviral activity.",253.26,"39809-25-1",{"v":34,"d":"34.00"},134.25,{"v":1,"d":"1.00"},3.95,"http://selleckchem.com/products/penciclovir.html","C10H15N5O3","free base","BRL-39123, VSA 671,NSC-759624","NC1=NC(=O)C2=C(N1)[N](CCC(CO)CO)C=N2",-1.533,3,4,5]
["S4185","Tiratricol","b5","L8000-12","in 10mM DMSO","THR","Metabolism","Tiratricol (also known as TRIAC or triiodothyroacetic acid) is a thyroid hormone analogue.",621.93,"51-24-1",{"v":100,"d":"100.00"},160.79,"<1","N/A","http://selleckchem.com/products/tiratricol.html","C14H9I3O4","free base","triiodothyroacetic acid","OC(=O)CC1=CC(=C(OC2=CC=C(O)C(=C2)I)C(=C1)I)I",4.547,2,1,4]
["S4186","Domiphen Bromide","c5","L8000-12","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Domiphen bromide (NSC-39415) is a quaternary ammonium antiseptic with actions as a cationic surfactant.",414.46,"538-71-6",{"v":83,"d":"83.00"},200.26,{"v":83,"d":"83.00"},200.26,"http://selleckchem.com/products/domiphen-bromide.html","C22H40NO.Br","free base","NSC-39415","[Br-].CCCCCCCCCCCC[N+](C)(C)CCOC1=CC=CC=C1",3.157,1,0,15]
["S4187","Salicylanilide","d5","L8000-12","in 10mM DMSO","Fungal,Integrase,Reverse Transcriptase","Microbiology","Salicylanilides (WR10019,2-Hydroxybenzanilide) are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities.",213.23,"87-17-2",{"v":43,"d":"43.00"},201.66,"<1","N/A","http://selleckchem.com/products/salicylanilide.html","C13H11NO2","free base","WR10019,2-Hydroxybenzanilide","OC1=CC=CC=C1C(=O)NC2=CC=CC=C2",2.372,1,2,2]
["S4188","Sasapyrine","e5","L8000-12","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Sasapyrine (Salsalate, NSC-49171) is a nonsteroidal oral anti-inflammatory agent.",258.23,"552-94-3",{"v":52,"d":"52.00"},201.37,"<1","N/A","http://selleckchem.com/products/sasapyrine.html","C14H10O5","free base","NSC-49171,Salsalate","OC(=O)C1=CC=CC=C1OC(=O)C2=CC=CC=C2O",2.649,3,1,4]
["S4190","Cinchophen","f5","L8000-12","in 10mM DMSO","Others","Others","Cinchophen(Cinconal) is an analgesic drug that is frequently used to treat gout.",249.26,"132-60-5",{"v":50,"d":"50.00"},200.59,"<1","N/A","http://selleckchem.com/products/cinchophen.html","C16H11NO2","free base","Cinconal","OC(=O)C1=C2C=CC=CC2=NC(=C1)C3=CC=CC=C3",3.593,2,0,2]
["S4192","Chlorquinaldol","g5","L8000-12","in 10mM DMSO","Anti-infection","Microbiology","Chlorquinaldol(Chloquinan) is an antimicrobial agent used for local antisepsy.",228.07,"72-80-0",{"v":46,"d":"46.00"},201.69,"<1","N/A","http://selleckchem.com/products/chlorquinaldol.html","C10H7Cl2NO","free base","Chloquinan","CC1=CC=C2C(=CC(=C(O)C2=N1)Cl)Cl",3.385,1,1,0]
["S4195","Broxyquinoline","h5","L8000-12","in 10mM DMSO","Anti-infection","Microbiology","Broxyquinoline(Dibromohydroxyquinoline) is an antiprotozoal agent and able to release oxygen free radicals from the water in mucous membranes.",302.95,"521-74-4",{"v":17,"d":"17.00"},56.11,"<1","N/A","http://selleckchem.com/products/broxyquinoline.html","C9H5Br2NO","free base","Dibromohydroxyquinoline","OC1=C2N=CC=CC2=C(Br)C=C1Br",3.271,1,1,0]
["S4196","Ethacridine lactate monohydrate","a6","L8000-12","in 10mM DMSO","Anti-infection","Microbiology","Ethacridine lactate monohydrate(Acrinol monohydrat) is an aromatic organic compound based on acridine used as an antiseptic agent.",361.39,"6402-23-9",{"v":72,"d":"72.00"},199.23,{"v":5,"d":"5.00"},13.84,"http://selleckchem.com/products/ethacridine-lactate-monohydrate.html","C15H15N3O.C3H6O3.H2O","Lactate","Acrinol monohydrat","O.CCOC1=CC2=C(N)C3=CC=C(N)C=C3N=C2C=C1.CC(O)C(O)=O",1.592,3,3,3]
["S4197","Bemegride","b6","L8000-12","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Bemegride(Bemegrid,3-Ethyl-3-methylglutarimide) is a central nervous system stimulant and antidote for barbiturate poisoning.",155.19,"64-65-3",{"v":31,"d":"31.00"},199.76,"<1","N/A","http://selleckchem.com/products/bemegride.html","C8H13NO2","free base","Bemegrid,3-Ethyl-3-methylglutarimide","CCC1(C)CC(=O)NC(=O)C1",0.578,2,1,1]
["S4201","Florfenicol","c6","L8000-12","in 10mM DMSO","Bacterial","Microbiology","Florfenicol (SCH-25298,(-)-Florfenicol) is a fluorinated synthetic analog of thiamphenicol with broad-spectrum, primarily bacteriostatic activity.",358.21,"73231-34-2",{"v":72,"d":"72.00"},{"v":201,"d":"201.00"},"<1","N/A","http://selleckchem.com/products/florfenicol.html","C12H14Cl2FNO4S","free base","SCH-25298,(-)-Florfenicol","C[S](=O)(=O)C1=CC=C(C=C1)C(O)C(CF)NC(=O)C(Cl)Cl",1.597,3,2,6]
["S4206","Cysteamine HCl","d6","L8000-12","in 10mM DMSO","Antioxidant","Metabolism","Cysteamine HCl(Mercaptamine) is an autophagy-stimulatory proteostasis regulator. Cysteamine can be used for the treatment of nephropathic cystinosis and an antioxidant.",113.61,"156-57-0",{"v":23,"d":"23.00"},202.45,{"v":23,"d":"23.00"},202.45,"http://selleckchem.com/products/cysteamine-hcl.html","C2H7NS.HCl","Hydrochloride","Mercaptamine","Cl.NCCS",0.166,0,1,1]
["S4207","Clofibric Acid","e6","L8000-12","in 10mM DMSO","PPAR","Metabolism","Clofibric acid(Chlorofibrinic acid) is a PPARα agonist and hypolipidemic agent.",214.65,"882-09-7",{"v":43,"d":"43.00"},200.33,"<1","N/A","http://selleckchem.com/products/clofibric-acid.html","C10H11ClO3","free base","Chlorofibrinic acid","CC(C)(OC1=CC=C(Cl)C=C1)C(O)=O",2.755,2,0,3]
["S4208","Chromocarb","f6","L8000-12","in 10mM DMSO","Others","Others","Chromocarb(Atremon) is a vasoprotectant.",190.15,"4940-39-0",{"v":38,"d":"38.00"},199.84,"<1","N/A","http://selleckchem.com/products/chromocarb.html","C10H6O4","free base","Atremon","OC(=O)C1=CC(=O)C2=CC=CC=C2O1",1.247,3,0,1]
["S4210","Benzocaine","g6","L8000-12","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Benzocaine(ethyl 4-aminobenzoate) is the ethyl ester of p-aminobenzoic acid (PABA), it is a local anesthetic commonly used as a topical pain reliever or in cough drops.",165.19,"94-09-7",{"v":33,"d":"33.00"},199.77,"<1","N/A","http://selleckchem.com/products/benzocaine.html","C9H11NO2","Free Base","ethyl 4-aminobenzoate","CCOC(=O)C1=CC=C(N)C=C1",1.287,2,1,3]
["S4213","Dirithromycin","a7","L8000-12","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Dirithromycin (LY-237216, ASE 136,Dynabac) is a macrolide glycopeptide antibiotic by binding to the 50S subunit of the 70S bacterial ribosome to inhibit the translocation of peptides.",835.07,"62013-04-1",{"v":11,"d":"11.00"},13.17,"<1","N/A","http://selleckchem.com/products/dirithromycin.html","C42H78N2O14","free base","LY-237216, ASE 136,Dynabac","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)C4NC(COCCOC)OC(C4C)C1(C)O",1.869,10,3,12]
["S4214","Sucralose","b7","L8000-12","in 10mM DMSO","Others","Others","Sucralose (E955,Trichloro Sucrose) is an artificial and noncaloric sweetener, not broken down by the body.",397.63,"56038-13-2",{"v":80,"d":"80.00"},201.19,{"v":80,"d":"80.00"},201.19,"http://selleckchem.com/products/sucralose.html","C12H19Cl3O8","free base","E955,Trichloro Sucrose","OCC1OC(OC2(CCl)OC(CCl)C(O)C2O)C(O)C(O)C1Cl",-0.697,3,5,5]
["S4216","Valnemulin HCl","c7","L8000-12","in 10mM DMSO","Bacterial","Microbiology","Valnemulin HCl is a broad-spectrum bacteriostatic agent inhibiting protein synthesis in bacteria by binding to the peptidyl transferase component of the 50S subunit of ribosomes.",601.28,"133868-46-9",{"v":100,"d":"100.00"},166.31,{"v":100,"d":"100.00"},166.31,"http://selleckchem.com/products/valnemulin-hcl.html","C31H52N2O5S.HCl","Hydrochloride","N/A","Cl.CC(C)C(N)C(=O)NCC(C)(C)SCC(=O)OC1CC(C)(C=C)C(O)C(C)C23CCC(C)C1(C)C2C(=O)CC3",4.048,4,3,10]
["S4217","Liothyronine Sodium","d7","L8000-12","in 10mM DMSO","THR","Metabolism","Liothyronine Sodium(Cytomel) is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis.",672.96,"55-06-1",{"v":100,"d":"100.00"},{"v":148.6,"d":"148.60"},"<1","N/A","http://selleckchem.com/products/liothyronine-sodium.html","C15H12I3NO4.Na","sodium","Cytomel","[Na+].NC(CC1=CC(=C(OC2=CC=C(O)C(=C2)I)C(=C1)I)I)C([O-])=O",2.452,1,2,5]
["S4221","Benzbromarone","e7","L8000-12","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Benzbromarone(Desuric) is a CYP2C9 inhibitor, it binds to CYP2C9 with Ki value of 19.3 nM.",424.08,"3562-84-3",{"v":85,"d":"85.00"},200.43,"<1","N/A","http://selleckchem.com/products/benzbromarone.html","C17H12Br2O3","free base","Desuric","CCC1=C(C(=O)C2=CC(=C(O)C(=C2)Br)Br)C3=C(O1)C=CC=C3",5.604,2,1,3]
["S4223","Mevastatin","f7","L8000-12","in 10mM DMSO","HMG-CoA Reductase","Metabolism","Mevastatin (ML-236B,Compactin) is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 times greater than the HMG-CoA substrate itself.",390.51,"73573-88-3",{"v":78,"d":"78.00"},199.74,"<1","N/A","http://selleckchem.com/products/mevastatin.html","C23H34O5","free base","ML-236B,Compactin","CCC(C)C(=O)OC1CCC=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C12",3.966,4,1,7]
["S4224","Erythritol","g7","L8000-12","in 10mM DMSO","Others","Others","Erythritol(meso-Erythritol) is a sugar alcohol used as low-calorie sweetener.",122.12,"149-32-6",{"v":24,"d":"24.00"},196.53,{"v":24,"d":"24.00"},196.53,"http://selleckchem.com/products/erythritol.html","C4H10O4","free base","meso-Erythritol","OCC(O)C(O)CO",-1.919,0,4,3]
["S4225","Mexiletine HCl","h7","L8000-12","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Mexiletine HCl (KO1173,Mexitil) belongs to Class IB anti-arrhythmic group of medicines, inhibits sodium channels to reduce the inward sodium current.",215.72,"5370-01-4",{"v":43,"d":"43.00"},199.33,{"v":43,"d":"43.00"},199.33,"http://selleckchem.com/products/mexiletine-hcl.html","C11H17NO.HCl","Hydrochloride","KO1173,Mexitil","Cl.CC(N)COC1=C(C)C=CC=C1C",2.716,1,1,3]
["S4227","Fidaxomicin","a8","L8000-12","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Fidaxomicin (OPT-80, PAR-101,Dificid) is a narrow spectrum macrocyclic antibiotic that inhibits RNA polymerase sigma subunit.",1058.04,"873857-62-6",{"v":100,"d":"100.00"},94.51,"<1","N/A","http://selleckchem.com/products/fidaxomicin.html","C52H74Cl2O18","free base","OPT-80, PAR-101,Dificid","CCC1\\C=C(C)/C(O)C\\C=C\\C=C(COC2OC(C)C(OC(=O)C3=C(CC)C(=C(O)C(=C3O)Cl)Cl)C(O)C2OC)\\C(=O)OC(C\\C=C(C)\\C=C(C)\\C1OC4OC(C)(C)C(OC(=O)C(C)C)C(O)C4O)C(C)O",7.774,11,7,15]
["S4230","Oxaprozin","b8","L8000-12","in 10mM DMSO","COX","Metabolism","Oxaprozin (WY-21743,nsc 310839) is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID) used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis.",293.32,"21256-18-8",{"v":59,"d":"59.00"},201.15,"<1","N/A","http://selleckchem.com/products/oxaprozin.html","C18H15NO3","free base","WY-21743,nsc 310839","OC(=O)CCC1=NC(=C(O1)C2=CC=CC=C2)C3=CC=CC=C3",{"v":3.59,"d":"3.590"},3,0,5]
["S4231","Pilocarpine HCl","c8","L8000-12","in 10mM DMSO","AChR","Neuronal Signaling","Pilocarpine HCl (NSC 5746) is a nonselective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy.",244.72,"54-71-7",{"v":48,"d":"48.00"},196.14,{"v":48,"d":"48.00"},196.14,"http://selleckchem.com/products/pilocarpine-hcl.html","C11H16N2O2.HCl","Hydrochloride","NSC 5746 HCl","Cl.CCC1C(COC1=O)CC2=CN=C[N]2C",1.347,3,0,3]
["S4237","Primaquine Diphosphate","d8","L8000-12","in 10mM DMSO","Anti-infection","Microbiology","Primaquine Diphosphate is a transmission-blocking anti-malarial clinically available, displaying a marked activity against gametocytes of all species of human malaria.",455.34,"63-45-6",{"v":91,"d":"91.00"},199.85,{"v":91,"d":"91.00"},199.85,"http://selleckchem.com/products/primaquine-diphosphate.html","C15H21N3O.2H3O4P","Diphosphate","N/A","COC1=CC(=C2N=CC=CC2=C1)NC(C)CCCN.O[P](O)(O)=O.O[P](O)(O)=O",1.062,2,2,6]
["S4238","Cepharanthine","e8","L8000-12","in 10mM DMSO","TNF-alpha","Apoptosis","Cepharanthine (NSC-623442) is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production.",606.71,"481-49-2",{"v":100,"d":"100.00"},164.82,"<1","N/A","http://selleckchem.com/products/cepharanthine.html","C37H38N2O6","free base","NSC-623442","COC1=C2OC3=CC=C(CC4N(C)CCC5=C4C(=C6OCOC6=C5)OC7=C(OC)C=C8CCN(C)C(CC(=C2)C=C1)C8=C7)C=C3",7.019,6,0,2]
["S4239","Bergapten","f8","L8000-12","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Bergapten is a psoralen that can be photoactivated and is capable of crossing-linking DNA, covalently modifying proteins and lipids, and consequently inhibiting cell replication.",216.19,"484-20-8",{"v":5,"d":"5.00"},23.13,"<1","N/A","http://selleckchem.com/products/bergapten.html","C12H8O4","free base","N/A","COC1=C2C=COC2=CC3=C1C=CC(=O)O3",2.187,4,0,1]
["S4240","Doxylamine Succinate","g8","L8000-12","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Doxylamine succinate competitively inhibits histamine at H1 receptors with substantial sedative and anticholinergic effects.",388.46,"562-10-7",{"v":78,"d":"78.00"},200.79,{"v":78,"d":"78.00"},200.79,"http://selleckchem.com/products/doxylamine-succinate.html","C17H22N2O.C4H6O4","Succinate","N/A","CN(C)CCOC(C)(C1=CC=CC=C1)C2=CC=CC=N2.OC(=O)CCC(O)=O",-0.527,4,0,9]
["S4242","Cetrimonium Bromide (CTAB)","h8","L8000-12","in 10mM DMSO","Anti-infection","Microbiology","Cetrimonium Bromide (CTAB) is a known component of the broad-spectrum antiseptic cetrimide, which is a mixture of different quaternary ammonium salts.",364.45,"57-09-0",{"v":5,"d":"5.00"},13.72,{"v":100,"d":"100.00"},274.39,"http://selleckchem.com/products/cetrimonium-bromide.html","C19H42N.Br","free base","N/A","[Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C",{"v":3.35,"d":"3.350"},0,0,15]
["S4243","Deoxycorticosterone acetate","a9","L8000-12","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Deoxycorticosterone acetate (11-Deoxycorticosterone, DOC, Cortexone) is a steroid hormone used for intramuscular injection for replacement therapy of the adrenocortical steroid.",{"v":372.5,"d":"372.50"},"56-47-3",{"v":11,"d":"11.00"},29.53,"<1","N/A","http://selleckchem.com/products/deoxycorticosterone-acetate.html","C23H32O4","free base","11-Deoxycorticosterone acetate, DOC acetate, Cortexone acetate","CC(=O)OCC(=O)C1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C",3.567,4,0,4]
["S4244","Serotonin HCl","b9","L8000-12","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Serotonin HCl (5-HT) is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist.",212.68,"153-98-0",{"v":42,"d":"42.00"},197.48,{"v":42,"d":"42.00"},197.48,"http://selleckchem.com/products/serotonin-hcl.html","C10H12N2O.HCl","Hydrochloride","5-HT HCl","Cl.NCCC1=C[NH]C2=CC=C(O)C=C12",{"v":1.69,"d":"1.690"},0,3,2]
["S4246","Tranylcypromine (2-PCPA) HCl","c9","L8000-12","in 10mM DMSO","MAO","Metabolism","Tranylcypromine HCl (2-PCPA, SKF-385, Parnate) is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively.",169.65,"1986-47-6",{"v":33,"d":"33.00"},194.52,{"v":33,"d":"33.00"},194.52,"http://selleckchem.com/products/tranylcypromine-2-pcpa-hcl.html","C9H12ClN","Hydrochloride","SKF-385 HCl, Parnate,2-PCPA","Cl.NC1CC1C2=CC=CC=C2",2.309,0,1,1]
["S4247","Prucalopride Succinate","d9","L8000-12","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Prucalopride(R-108512) is a selective, high affinity 5-HT4 receptor agonist. The Ki values of prucalopride for human 5-HT(4a) and 5-HT(4b) receptor are 2.5 nM and 8 nM, respectively.",485.96,"179474-85-2",{"v":97,"d":"97.00"},{"v":199.6,"d":"199.60"},{"v":97,"d":"97.00"},{"v":199.6,"d":"199.60"},"http://selleckchem.com/products/prucalopride-succinat.html","C18H26ClN3O3.C4H6O4","Succinat","R-108512","COCCCN1CCC(CC1)NC(=O)C2=C3OCCC3=C(N)C(=C2)Cl.OC(=O)CCC(O)=O",-2.338,5,2,9]
["S4249","Flopropione","e9","L8000-12","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Flopropione is a spasmolytic or antispasmodic agent, and acts as a 5-HT1A receptor antagonist.",182.17,"2295-58-1",{"v":36,"d":"36.00"},197.62,"<1","N/A","http://selleckchem.com/products/flopropione.html","C9H10O4","free base","N/A","CCC(=O)C1=C(O)C=C(O)C=C1O",{"v":1.51,"d":"1.510"},1,3,2]
["S4250","Sulfamethoxypyridazine","f9","L8000-12","in 10mM DMSO","Anti-infection","Microbiology","Sulfamethoxypyridazine (CL 13494) is a long-acting sulfonamide for treatment of Dermatitis herpetiformis.",{"v":280.3,"d":"280.30"},"80-35-3",{"v":56,"d":"56.00"},199.79,"<1","N/A","http://selleckchem.com/products/sulfamethoxypyridazine.html","C11H12N4O3S","free base","CL 13494","COC1=NN=C(N[S](=O)(=O)C2=CC=C(N)C=C2)C=C1",1.014,5,2,4]
["S4253","Epinastine HCl","h9","L8000-12","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Epinastine (WAL-801CL) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.",285.77,"108929-04-0",{"v":57,"d":"57.00"},199.46,{"v":57,"d":"57.00"},199.46,"http://selleckchem.com/products/epinastine-hcl.html","C16H15N3.HCl","Hydrochloride","WAL-801CL HCl","Cl.NC1=NCC2N1C3=CC=CC=C3CC4=CC=CC=C24",3.164,1,1,0]
["S4255","Quinacrine 2HCl","a10","L8000-12","in 10mM DMSO","Phospholipase (e.g. PLA)","Metabolism","Quinacrine 2HCl(Quinacrine dihydrochloride) is a lipophilic cationic drug with multiple actions that is commonly used as an anti-protozoal agent. Quinacrine is an effective  phospholipase A2 inhibitor.",472.88,"69-05-6",{"v":14,"d":"14.00"},29.61,{"v":53,"d":"53.00"},112.08,"http://selleckchem.com/products/quinacrine-2hcl.html","C23H30ClN3O.2HCl","Dihydrochloride","Quinacrine dihydrochloride","Cl.Cl.CCN(CC)CCCC(C)NC1=C2C=C(OC)C=CC2=NC3=CC(=CC=C13)Cl",{"v":6.43,"d":"6.430"},2,1,9]
["S4256","Buspirone HCl","b10","L8000-12","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Buspirone(Buspirone hydrochloride) is a serotonergic (5HT(1A) receptor agonist) anxiolytic drug with some D(2) dopaminergic effect, used for anxiety disorders.",421.96,"33386-08-2",{"v":84,"d":"84.00"},199.07,{"v":84,"d":"84.00"},199.07,"http://selleckchem.com/products/buspirone-hcl.html","C21H31N5O2.HCl","Hydrochloride","Buspirone hydrochloride","Cl.O=C1CC2(CCCC2)CC(=O)N1CCCCN3CCN(CC3)C4=NC=CC=N4",2.403,4,0,6]
["S4257","Alizapride HCl","c10","L8000-12","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Alizapride HCl(Alizapride hydrochloride) is a dopamine receptor antagonist used for the theropy of nausea and vomiting.",351.83,"59338-87-3",{"v":42,"d":"42.00"},119.38,{"v":70,"d":"70.00"},198.96,"http://selleckchem.com/products/alizapride-hcl.html","C16H21N5O2.HCl","hydrochloride","Alizapride hydrochloride","Cl.COC1=CC2=C(C=C1C(=O)NCC3CCCN3CC=C)N=N[NH]2",2.253,4,2,6]
["S4259","Vilazodone HCl","d10","L8000-12","in 10mM DMSO","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Vilazodone HCl(EMD68843,SB659746A) is a selective serotonin reuptake inhibitor (SSRI) and  a partial agonist of 5-HT1A receptors, used for the treatment of major depressive disorder.",477.99,"163521-08-2",{"v":96,"d":"96.00"},200.84,"<1","N/A","http://selleckchem.com/products/vilazodone-hcl.html","C26H27N5O2.HCl","Hydrochloride","EMD68843,SB659746A","Cl.NC(=O)C1=CC2=C(O1)C=CC(=C2)N3CCN(CCCCC4=C[NH]C5=C4C=C(C=C5)C#N)CC3",4.918,2,2,7]
["S4260","Tamibarotene","e10","L8000-12","in 10mM DMSO","Retinoid Receptor","Metabolism","Tamibarotene(Am 80) is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ.",351.44,"94497-51-5",{"v":70,"d":"70.00"},199.18,"<1","N/A","http://selleckchem.com/products/tamibarotene.html","C22H25NO3","free base","Am 80","CC1(C)CCC(C)(C)C2=C1C=CC(=C2)NC(=O)C3=CC=C(C=C3)C(O)=O",4.673,2,1,3]
["S4263","Efaproxiral Sodium","f10","L8000-12","in 10mM DMSO","ROS","Immunology & Inflammation","Efaproxiral Sodium(RSR13 Sodium) is a synthetic allosteric modifier of hemoglobin, decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy. Efaproxiral Sodium is used for brain metastases originating from breast cancer.",363.38,"170787-99-2",{"v":73,"d":"73.00"},200.89,{"v":73,"d":"73.00"},200.89,"http://selleckchem.com/products/efaproxiral-sodium.html","C20H23NO4.Na","Sodium salt","RSR13 Sodium","[Na+].CC1=CC(=CC(=C1)NC(=O)CC2=CC=C(OC(C)(C)C([O-])=O)C=C2)C",2.408,2,1,6]
["S4265","Nicaraven","g10","L8000-12","in 10mM DMSO","Others","Others","Nicaraven is a hydroxyl radical scavenger with antivasospastic and neuroprotective effects.",284.31,"79455-30-4",{"v":57,"d":"57.00"},200.49,{"v":57,"d":"57.00"},200.49,"http://selleckchem.com/products/nicaraven.html","C15H16N4O2","free base","N/A","CC(CNC(=O)C1=CN=CC=C1)NC(=O)C2=CN=CC=C2",-0.029,4,2,5]
["S4266","Brimonidine Tartrate","h10","L8000-12","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Brimonidine Tartrate(UK 1434 Tartrate) is a highly selective α-adrenergic receptor agonist with EC50 of 0.45 nM for the α2A adrenoreceptor, and used to treat open-angle glaucoma or ocular hypertension.",442.22,"70359-46-5",{"v":88,"d":"88.00"},{"v":199,"d":"199.00"},{"v":75,"d":"75.00"},{"v":169.6,"d":"169.60"},"http://selleckchem.com/products/brimonidine-tartrate.html","C15H16BrN5O6","Tartrate","UK 1434 Tartrate","OC(C(O)C(O)=O)C(O)=O.BrC1=C2N=CC=NC2=CC=C1NC3=NCCN3",-0.426,5,4,5]
["S4267","Diacerein","a11","L8000-12","in 10mM DMSO","Interleukins","Immunology & Inflammation","Diacerein is an inhibitor of pro-inflammatory cytokine Interleukin-1B (IL-1B) production, prescribed for osteoarthritis and chronic inflammatory arthritis.",368.29,"13739-02-1",{"v":48,"d":"48.00"},130.33,"<1","N/A","http://selleckchem.com/products/diacerein.html","C19H12O8","free base","N/A","CC(=O)OC1=CC=CC2=C1C(=O)C3=C(C=C(C=C3OC(C)=O)C(O)=O)C2=O",1.973,7,0,5]
["S4268","Flufenamic acid","b11","L8000-12","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Flufenamic Acid is an anti-inflammatory agent, and also acts as an ion channel modulator.",281.23,"530-78-9",{"v":56,"d":"56.00"},199.13,"<1","N/A","http://selleckchem.com/products/flufenamic-acid.html","C14H10F3NO2","free base","N/A","OC(=O)C1=CC=CC=C1NC2=CC=CC(=C2)C(F)(F)F",3.952,1,1,4]
["S4269","Vinorelbine ditartrate (KW-2307)","c11","L8000-12","in 10mM DMSO","Apoptosis related,Autophagy,Microtubule Associated","Cytoskeletal Signaling","Vinorelbine Tartrate (KW-2307, Nor-5'-anhydrovinblastine ditartrate) is a semi-synthetic vinca alkaloid, and inhibits mitosis through interaction with tubulin. Vinorelbine Tartrate exhibits anti-tumor activities via inducing the mitotic apoptosis, autophagy and inflammation.",1079.11,"125317-39-7",{"v":100,"d":"100.00"},92.67,{"v":100,"d":"100.00"},92.67,"http://selleckchem.com/products/vinorelbine-tartrate.html","C45H54N4O8.2C4H6O6","ditartrate","Nor-5'-anhydrovinblastine ditartrate,KW-2307","CCC1=CC2CN(C1)CC3=C([NH]C4=C3C=CC=C4)C(C2)(C(=O)OC)C5=C(OC)C=C6N(C)C7C(O)(C(OC(C)=O)C8(CC)C=CCN9CCC7(C89)C6=C5)C(=O)OC.OC(C(O)C(O)=O)C(O)=O.OC(C(O)C(O)=O)C(O)=O",{"v":-4,"d":"-4.000"},11,5,16]
["S4270","Oxiracetam","d11","L8000-12","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Oxiracetam (ISF 2522), a cyclic derivative of gamma-aminobutyric acid (GABA), is used as a nootropic drug to improve memory and learning.",158.16,"62613-82-5",{"v":31,"d":"31.00"},{"v":196,"d":"196.00"},{"v":31,"d":"31.00"},{"v":196,"d":"196.00"},"http://selleckchem.com/products/oxiracetam.html","C6H10N2O3","free base","ISF 2522","NC(=O)CN1CC(O)CC1=O",-2.143,2,2,2]
["S4277","Bambuterol HCl","e11","L8000-12","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Bambuterol HCl(Bambuterol hydrochloride,KWD-2183 hydrochloride) is a potent β-adrenoceptor agonist, used in the treatment of asthma.",{"v":403.9,"d":"403.90"},"81732-46-9",{"v":80,"d":"80.00"},198.07,{"v":72,"d":"72.00"},178.26,"http://selleckchem.com/products/bambuterol-hci.html","C18H29N3O5.HCl","Hydrochloride","Bambuterol hydrochloride,KWD-2183 hydrochloride","Cl.CN(C)C(=O)OC1=CC(=CC(=C1)OC(=O)N(C)C)C(O)CNC(C)(C)C",2.109,4,2,8]
["S4278","Carteolol HCl","f11","L8000-12","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Carteolol HCl(Carteolol hydrochloride,OPC-1085 hydrochloride) is a β-adrenoceptor antagonist, used for the treatment of glaucoma.",328.83,"51781-21-6",{"v":65,"d":"65.00"},197.67,{"v":65,"d":"65.00"},197.67,"http://selleckchem.com/products/carteolol-hci.html","C16H25ClN2O3","Hydrochloride","Carteolol hydrochloride,OPC-1085 hydrochloride","Cl.CC(C)(C)NCC(O)COC1=C2CCC(=O)NC2=CC=C1",1.664,2,3,6]
["S4280","Meclofenoxate (Centrophenoxine) HCl","g11","L8000-12","in 10mM DMSO","Transferase","Metabolism","Meclofenoxate (Centrophenoxine) HCl is an anti-aging drug used to treat the symptoms of senile dementia and Alzheimer's disease, and also inhibits the activity of cholinephosphotransferase.",294.17,"3685-84-5",{"v":58,"d":"58.00"},197.16,{"v":58,"d":"58.00"},197.16,"http://selleckchem.com/products/meclofenoxate-centrophenoxine-hci.html","C12H17Cl2NO3","Hydrochloride","Centrophenoxine","Cl.CN(C)CCOC(=O)COC1=CC=C(Cl)C=C1",2.705,3,0,7]
["S4282","Nelfinavir (AG 1343) Mesylate","h11","L8000-12","in 10mM DMSO","COVID-19,HIV Protease","Proteases","Nelfinavir Mesylate (Viracept, AG1343) is a potent HIV protease inhibitor with Ki of 2 nM.",663.89,"159989-65-8",{"v":100,"d":"100.00"},150.63,"<1","N/A","http://selleckchem.com/products/nelfinavir-mesylate.html","C33H49N3O7S2","Mesylate","Viracept, AG1343","CC1=C(C=CC=C1O)C(=O)NC(CSC2=CC=CC=C2)C(O)CN3CC4CCCCC4CC3C(=O)NC(C)(C)C.C[S](O)(=O)=O",4.871,2,4,10]
["S4283","Cyclobenzaprine HCl","a2","L8000-13","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Cyclobenzaprine HCl(Cyclobenzaprine hydrochloride) is a muscle relaxant by blocking pain sensations, used for the treatment of muscle spasms; A 5-HT2 receptor antagonist.",311.85,"6202-23-9",{"v":62,"d":"62.00"},198.81,{"v":62,"d":"62.00"},198.81,"http://selleckchem.com/products/cyclobenzaprine-hci.html","C20H22ClN","Hydrochloride","Cyclobenzaprine hydrochloride","Cl.CN(C)CCC=C1C2=C(C=CC=C2)C=CC3=C1C=CC=C3",4.709,0,0,3]
["S4285","Ospemifene","b2","L8000-13","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Ospemifene(FC-1271a) is a non-hormonal selective estrogen receptor modulator (SERM), used for the treatment of dyspareunia.",378.89,"128607-22-7",{"v":75,"d":"75.00"},197.95,"<1","N/A","http://selleckchem.com/products/ospemifene.html","C24H23ClO2","free base","FC-1271a","OCCOC1=CC=C(C=C1)\\C(=C(\\CCCl)C2=CC=CC=C2)C3=CC=CC=C3",{"v":5.62,"d":"5.620"},1,1,8]
["S4288","Chloroambucil","c2","L8000-13","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Chloroambucil (Chlorambucil,CB-1348,WR-139013) is a nitrogen mustard alkylating agent, used in the treatment of chronic lymphocytic leukemia.",304.21,"305-03-3",{"v":60,"d":"60.00"},197.23,"<1","N/A","http://selleckchem.com/products/chloroambucil.html","C14H19Cl2NO2","free base","Chlorambucil,CB-1348,WR-139013","OC(=O)CCCC1=CC=C(C=C1)N(CCCl)CCCl",3.899,1,0,9]
["S4289","Metoclopramide HCl","d2","L8000-13","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Metoclopramide HCl(Metoclopramide hydrochloride) is a selective dopamine D2 receptor antagonist, used for the treatment of nausea and vomiting.",336.26,"7232-21-5",{"v":67,"d":"67.00"},199.25,{"v":67,"d":"67.00"},199.25,"http://selleckchem.com/products/metoclopramide-hcl.html","C14H23Cl2N3O2","Hydrochloride","Metoclopramide hydrochloride","Cl.CCN(CC)CCNC(=O)C1=CC(=C(N)C=C1OC)Cl",2.157,2,2,7]
["S4291","Labetalol HCl","e2","L8000-13","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Labetalol HCl(AH-5158 hydrochloride,Labetalol hydrochloride,Sch-15719W) is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors, used in the treatment of high blood pressure.",364.87,"32780-64-6",{"v":72,"d":"72.00"},197.33,{"v":8,"d":"8.00"},21.93,"http://selleckchem.com/products/labetalol-hcl.html","C19H25ClN2O3","Hydrochloride","AH-5158 hydrochloride,Labetalol hydrochloride,Sch-15719W","Cl.CC(CCC1=CC=CC=C1)NCC(O)C2=CC(=C(O)C=C2)C(N)=O",2.737,1,4,8]
["S4292","Diphenidol HCl","f2","L8000-13","in 10mM DMSO","AChR","Neuronal Signaling","Diphenidol HCl(Diphenidol hydrochloride) is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02, respectively, used in the treatment of vomiting and vertigo.",345.91,"3254-89-5",{"v":69,"d":"69.00"},199.47,{"v":13,"d":"13.00"},37.58,"http://selleckchem.com/products/diphenidol-hcl.html","C21H28ClNO","Hydrochloride","Diphenidol hydrochloride","Cl.OC(CCCN1CCCCC1)(C2=CC=CC=C2)C3=CC=CC=C3",4.774,0,0,6]
["S4294","Procainamide HCl","g2","L8000-13","in 10mM DMSO","DNA Methyltransferase,Sodium Channel","Transmembrane Transporters","Procainamide HCl is a sodium channel blocker, and also a DNA methyltransferase inhibitor, used in the treatment of cardiac arrhythmias.",271.79,"614-39-1",{"v":54,"d":"54.00"},198.68,{"v":54,"d":"54.00"},198.68,"http://selleckchem.com/products/procainamide-hcl.html","C13H22ClN3O","Hydrochloride","N/A","Cl.CCN(CC)CCNC(=O)C1=CC=C(N)C=C1",1.509,1,2,6]
["S4295","Meclofenamate Sodium","h2","L8000-13","in 10mM DMSO","COX,FTO","Neuronal Signaling","Meclofenamate Sodium(CI 583) is a dual COX-1/COX-2 inhibitor with IC50 of 40 nM and 50 nM, respectively, used in the treatment of joint, muscular pain, arthritis and dysmenorrhea. Meclofenamate Sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat mass and obesity-associated (FTO) enzyme inhibitor.",318.13,"6385-02-0",{"v":63,"d":"63.00"},198.03,{"v":63,"d":"63.00"},198.03,"http://selleckchem.com/products/meclofenamate-sodium.html","C14H11Cl2NO2.Na","Sodium Salt","CI 583","CC1=C(Cl)C(=C(Cl)C=C1)NC2=CC=CC=C2C(=O)O[Na]",4.915,2,1,4]
["S4297","Mupirocin","a3","L8000-13","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Mupirocin(BRL-4910A,Pseudomonic acid) is an isoleucyl t-RNA synthetase inhibitor, used in the treatment of bacterial skin infections.",500.62,"12650-69-0",{"v":100,"d":"100.00"},199.75,{"v":46,"d":"46.00"},91.89,"http://selleckchem.com/products/mupirocin.html","C26H44O9","free base","BRL-4910A,Pseudomonic acid","CC(O)C(C)C1OC1CC2COC(C\\C(C)=C\\C(=O)OCCCCCCCCC(O)=O)C(O)C2O",2.739,5,3,17]
["S4299","Dicoumarol","b3","L8000-13","in 10mM DMSO","PDHK","Metabolism","Dicoumarol is a competitive NADPH quinone oxidoreductase (NQO1) inhibitor,and used as an anticoagulant by interfering with the metabolism of vitamin K.",336.29,"66-76-2",{"v":67,"d":"67.00"},199.23,"<1","N/A","http://selleckchem.com/products/dicoumarol.html","C19H12O6","free base","Dicumarol","OC1=C(CC2=C(O)C3=C(OC2=O)C=CC=C3)C(=O)OC4=CC=CC=C14",2.789,4,2,2]
["S4303","9-Aminoacridine","c3","L8000-13","in 10mM DMSO","Anti-infection","Microbiology","9-Aminoacridine (Aminacrine) is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix.",194.23,"90-45-9",{"v":38,"d":"38.00"},195.64,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/9-aminoacridine.html","C13H10N2","free base","Aminacrine","NC1=C2C=CC=CC2=NC3=CC=CC=C13",2.606,1,1,0]
["S4307","Auranofin","d3","L8000-13","in 10mM DMSO","Bacterial,Thioredoxin Reductase","Microbiology","Auranofin (Ridaura, SKF-39162) is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 μM. Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis.",678.48,"34031-32-8",{"v":100,"d":"100.00"},147.39,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/auranofin.html","C20H34AuO9PS","Free Base","Ridaura, SKF39162","CCP(|[Au]SC1OC(COC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O)(CC)CC",1.407,9,0,14]
["S4308","Benzthiazide","e3","L8000-13","in 10mM DMSO","Others","Others","Benzthiazide is a thiazide diuretic, promoting water loss from the body.",431.94,"91-33-8",{"v":86,"d":"86.00"},{"v":199.1,"d":"199.10"},"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/benzthiazide.html","C15H14ClN3O4S3","Free Base","Benzothiazide","N[S](=O)(=O)C1=CC2=C(C=C1Cl)N=C(CSCC3=CC=CC=C3)N[S]2(=O)=O",1.966,5,2,5]
["S4309","Bromocriptine Mesylate","f3","L8000-13","in 10mM DMSO","Others","Others","Bromocriptine, an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.",{"v":750.7,"d":"750.70"},"22260-51-1",{"v":100,"d":"100.00"},133.21,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/bromocriptine-mesylate.html","C32H40BrN5O5.CH4O3S","Mesylate","N/A","CC(C)CC1N2C(=O)C(NC(=O)C3CN(C)C4CC5=C(Br)[NH]C6=C5C(=CC=C6)C4=C3)(OC2(O)C7CCCN7C1=O)C(C)C.C[S](O)(=O)=O",3.949,4,2,5]
["S4316","Clopamide","g3","L8000-13","in 10mM DMSO","Others","Others","Clopamide is categorised as a thiazide-like diuretic and works in similar way as the thiazide diuretics do.",345.84,"636-54-4",{"v":69,"d":"69.00"},199.51,{"v":-1,"d":"-1.00"},"N/A","http://www.selleck.cn/products/clopamide.html","C14H20ClN3O3S","Free Base","N/A","CC1CCCC(C)N1NC(=O)C2=CC=C(Cl)C(=C2)[S](N)(=O)=O",1.793,3,2,3]
["S4317","Clorgyline HCl","h3","L8000-13","in 10mM DMSO","MAO","Others","Clorgiline is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A).",308.63,"17780-75-5",{"v":62,"d":"62.00"},200.89,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/clorgyline-hcl.html","C13H15Cl2NO.HCl","hydrochloride","N/A","Cl.CN(CCCOC1=CC=C(Cl)C=C1Cl)CC#C",4.917,1,0,6]
["S4330","Isoetharine Mesylate","a4","L8000-13","in 10mM DMSO","Others","Others","Isoetharine is a selective beta2-adrenergic receptor agonist, which gives quick relief for bronchospasm and asthma.",335.42,"7279-75-6",{"v":67,"d":"67.00"},199.75,{"v":67,"d":"67.00"},199.75,"http://www.selleckchem.com/products/isoetharine-mesylate.html","C14H25NO6S","mesylate","N/A","CCC(NC(C)C)C(O)C1=CC=C(O)C(=C1)O.C[S](O)(=O)=O",1.586,0,4,5]
["S4334","Mesoridazine Besylate","b4","L8000-13","in 10mM DMSO","Others","Others","N/A",544.75,"32672-69-8",{"v":100,"d":"100.00"},183.57,{"v":100,"d":"100.00"},183.57,"http://www.selleckchem.com/products/mesoridazine-besylate.html","C27H32N2O4S3","besylate","N/A","CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)[S](C)=O.O[S](=O)(=O)C5=CC=CC=C5",5.614,1,0,5]
["S4335","Metaproterenol Sulfate","c4","L8000-13","in 10mM DMSO","Others","Others","N/A",520.59,"5874-97-5",{"v":100,"d":"100.00"},192.09,{"v":100,"d":"100.00"},192.09,"http://www.selleckchem.com/products/metaproterenol-sulfate.html","C22H36N2O10S","sulfate","Orciprenaline Sulfate","CC(C)NCC(O)C1=CC(=CC(=C1)O)O.CC(C)NCC(O)C2=CC(=CC(=C2)O)O.O[S](O)(=O)=O",1.591,0,8,8]
["S4336","Metaraminol Bitartrate","d4","L8000-13","in 10mM DMSO","Others","Others","N/A",317.29,"33402-03-8",{"v":63,"d":"63.00"},198.56,{"v":63,"d":"63.00"},198.56,"http://www.selleckchem.com/products/metaraminol-bitartrate.html","C13H19NO8","bitartrate","Metaradrine Bitartrate","CC(N)C(O)C1=CC=CC(=C1)O.OC(C(O)C(O)=O)C(O)=O",-3.582,2,5,5]
["S4338","Methoxamine HCl","e4","L8000-13","in 10mM DMSO","Others","Others","Methoxamine is an α1-adrenergic receptor agonist, it induces vasoconstriction of skin and splanchnic blood vessels.",247.72,"61-16-5",{"v":50,"d":"50.00"},201.84,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/methoxamine-hcl.html","C11H17NO3.HCl","Hydrochloride","Vasoxine HCl","Cl.COC1=CC(=C(OC)C=C1)C(O)C(C)N",1.151,2,2,4]
["S4339","Meticrane","f4","L8000-13","in 10mM DMSO","Chloride Channel,Sodium Channel","Transmembrane Transporters","Meticrane is a diuretic that inhibits the reabsorption of sodium and chloride ions in the distal convoluted tubule. Meticrane is used to treat essential hypertension.",275.34,"1084-65-7",{"v":55,"d":"55.00"},199.75,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/meticrane.html","C10H13NO4S2","Free Base","N/A","CC1=C(C=C2C(=C1)CCC[S]2(=O)=O)[S](N)(=O)=O",1.078,4,1,1]
["S4344","Oxprenolol HCl","g4","L8000-13","in 10mM DMSO","Adrenergic Receptor","Others","Oxprenolol is a non-selective beta blocker with some intrinsic sympathomimetic activity.",301.81,"6452-73-9",{"v":60,"d":"60.00"},{"v":198.8,"d":"198.80"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/oxprenolol-hcl.html","C15H23NO3.HCl","hydrochloride","N/A","Cl.CC(C)NCC(O)COC1=CC=CC=C1OCC=C",2.614,2,2,9]
["S4345","Pentoxifylline","h4","L8000-13","in 10mM DMSO","PDE","Metabolism","Pentoxifylline is a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF and leukotriene synthesis, and reduces inflammation and innate immunity.",278.31,"6493-05-6",{"v":55,"d":"55.00"},197.62,{"v":55,"d":"55.00"},197.62,"http://www.selleckchem.com/products/pentoxifylline.html","C13H18N4O3","Free Base","N/A","C[N]1C=NC2=C1C(=O)N(CCCCC(C)=O)C(=O)N2C",0.507,4,0,5]
["S4353","Terfenadine","a5","L8000-13","in 10mM DMSO","Calcium Channel,Caspase,Histamine Receptor,NCX,Potassium Channel","Transmembrane Transporters","Terfenadine is an antihistamine, generally completely metabolizes to the active form fexofenadine in the liver by the enzyme cytochrome P450 CYP3A4 isoform.  Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.",471.67,"50679-08-8",{"v":94,"d":"94.00"},199.29,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/terfenadine.html","C32H41NO2","Free Base","N/A","CC(C)(C)C1=CC=C(C=C1)C(O)CCCN2CCC(CC2)C(O)(C3=CC=CC=C3)C4=CC=CC=C4",6.498,0,1,9]
["S4354","Thiostrepton","b5","L8000-13","in 10mM DMSO","Others","Others","Thiostrepton (Alaninamide, Bryamycin, Thiactin) is a natural cyclic oligopeptide antibiotic, derived from several strains of strepromycetes.",1664.89,"1393-48-2",{"v":100,"d":"100.00"},60.06,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/thiostrepton.html","C72H85N19O18S5","Free Base","Alaninamide, Bryamycin, Thiactin","CCC(C)C1NC2C=CC3=C(C=C(N=C3C2O)C(=O)OC(C)C4NC(=O)C5=CSC(=N5)C(NC(=O)C6CSC(=N6)\\C(NC(=O)C(NC(=O)C7=CSC(=N7)C8(CCC(=NC8C9=CSC4=N9)C%10=NC(=CS%10)C(=O)NC(=C)C(=O)NC(=C)C(N)=O)NC(=O)C(C)NC(=O)C(=C)NC(=O)C(C)NC1=O)C(C)O)=C\\C)C(C)(O)C(C)O)C(C)O",-1.361,20,16,12]
["S4358","Pimozide","c5","L8000-13","in 10mM DMSO","5-HT Receptor,Adrenergic Receptor,Dopamine Receptor,STAT","Neuronal Signaling","Pimozide (Orap, R6238) is an antagonist of Dopamine Receptors with Ki of 0.83 nM, 3.0 nM and 6600 nM for dopamine D3, D2 and D1 receptors, respectively. Pimozide also exhibits binding affinity at 5-HT1A and α1-adrenoceptor with Ki of 310 nM and 39 nM, respectively. Pimozide is an antipsychotic drug with anti-tumor activity and suppresses STAT3 and STAT5 activity.",461.55,"2062-78-4",{"v":92,"d":"92.00"},199.33,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/pimozide.html","C28H29F2N3O","Free Base","Orap, R6238","FC1=CC=C(C=C1)C(CCCN2CCC(CC2)N3C(=O)NC4=CC=CC=C34)C5=CC=C(F)C=C5",5.521,1,1,7]
["S4361","Cinoxacin","d5","L8000-13","in 10mM DMSO","Bacterial","Others","Cinoxacin is a chemotherapeutic agent that inhibits bacterial DNA synthesis.",262.22,"28657-80-9",{"v":7,"d":"7.00"},{"v":26.7,"d":"26.70"},"N/A","N/A","http://selleckchem.com/products/cinoxacin.html","C12H10N2O5","Free Base","N/A","CCN1N=C(C(O)=O)C(=O)C2=C1C=C3OCOC3=C2","N/A","N/A","N/A","N/A"]
["S4362","Glafenine HCl","e5","L8000-13","in 10mM DMSO","Others","Others","Glafenine is an anthranilic acid derivative with analgesic properties, which has been used previously in the treatment of pain.",409.26,"65513-72-6",{"v":81,"d":"81.00"},197.92,{"v":7,"d":"7.00"},{"v":17.1,"d":"17.10"},"http://www.selleckchem.com/products/glafenine-hcl.html","C19H18Cl2N2O4","hydrochloride","N/A","Cl.OCC(O)COC(=O)C1=CC=CC=C1NC2=CC=NC3=CC(=CC=C23)Cl",3.418,3,3,7]
["S4367","Suxibuzone","f5","L8000-13","in 10mM DMSO","Others","Others","Suxibuzone is a prodrug of the non steroidal anti inflammatory drug phenylbutazone, and is commonly used in horses.",438.47,"27470-51-5",{"v":88,"d":"88.00"},{"v":200.7,"d":"200.70"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/suxibuzone.html","C24H26N2O6","Free Base","N/A","CCCCC1(COC(=O)CCC(O)=O)C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3",3.504,5,0,11]
["S4373","Dicyclomine HCl","g5","L8000-13","in 10mM DMSO","Others","Others","Dicyclomine is an anticholinergic drug, a chemical released from nerves that stimulates muscles, by blocking the receptors for acetylcholine on smooth muscle (a type of muscle).",345.95,"67-92-5",{"v":22,"d":"22.00"},63.59,{"v":69,"d":"69.00"},199.45,"http://www.selleckchem.com/products/dicyclomine-hcl.html","C19H36ClNO2","Hydrochloride","Dicycloverine HCl","Cl.CCN(CC)CCOC(=O)C1(CCCCC1)C2CCCCC2",5.487,2,0,8]
["S4375","Mepenzolate Bromide","h5","L8000-13","in 10mM DMSO","Others","Others","Mepenzolate is a post-ganglionic parasympathetic inhibitor, it decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon.",420.34,"76-90-4",{"v":41,"d":"41.00"},199.34,{"v":1,"d":"1.00"},4.86,"http://www.selleckchem.com/products/mepenzolate-bromide.html","C21H26BrNO3","bromide","N/A","[Br-].C[N+]1(C)CCC(CC1)OC(=O)C(O)(C2=CC=CC=C2)C3=CC=CC=C3",-1.048,2,0,5]
["S4381","Proadifen HCl","a6","L8000-13","in 10mM DMSO","CYP450","Others","Proadifen is an inhibitor of cytochrome P450 enzymes, preventing some types of drug metabolism.",390.01,"62-68-0",{"v":77,"d":"77.00"},197.43,{"v":77,"d":"77.00"},197.43,"http://www.selleckchem.com/products/proadifen-hcl.html","C23H32ClNO2","hydrochloride","SKF 525-A HCl","Cl.CCCC(C(=O)OCCN(CC)CC)(C1=CC=CC=C1)C2=CC=CC=C2",5.762,2,0,11]
["S4382","Pyrilamine Maleate","b6","L8000-13","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Pyrilamine Maleate (Mepyramine)is a histamine H1 receptor inverse agonist, it binds to a G protein-coupled form of the receptor and promotes a G protein-coupled inactive state of the H1 receptor that interferes with the Gq/11-mediated signaling.",401.46,"59-33-6",{"v":80,"d":"80.00"},199.27,{"v":80,"d":"80.00"},199.27,"https://www.selleckchem.com/products/pyrilamine-maleate.html","C17H23N3O1.C4H4O4","maleate","Mepyramine Maleate","COC1=CC=C(CN(CCN(C)C)C2=CC=CC=N2)C=C1.OC(=O)\\C=C/C(O)=O",{"v":0.09,"d":"0.090"},4,0,9]
["S4387","Bendroflumethiazide","c6","L8000-13","in 10mM DMSO","Others","Others","N/A",421.41,"73-48-3",{"v":85,"d":"85.00"},{"v":201.7,"d":"201.70"},"N/A","N/A","http://selleckchem.com/products/bendroflumethiazide.html","C15H14F3N3O4S2","sulfonamide ","Bendrofluazide","N[S](=O)(=O)C1=CC2=C(NC(CC3=CC=CC=C3)N[S]2(=O)=O)C=C1C(F)(F)F","N/A","N/A","N/A","N/A"]
["S4394","Clofoctol","d6","L8000-13","in 10mM DMSO","Others","Others","N/A",365.34,"37693-01-9",{"v":73,"d":"73.00"},199.81,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/clofoctol.html","C21H26Cl2O","Free Base","N/A","CC(C)(C)CC(C)(C)C1=CC(=C(O)C=C1)CC2=CC=C(Cl)C=C2Cl",7.662,0,1,5]
["S4396","Digoxigenin","e6","L8000-13","in 10mM DMSO","Others","Others","N/A",390.51,"1672-46-4",{"v":78,"d":"78.00"},199.74,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/digoxigenin.html","C23H34O5","Free Base","Lanadigigenin","CC12CCC(O)CC1CCC3C2CC(O)C4(C)C(CCC34O)C5=CC(=O)OC5",2.276,2,2,1]
["S4404","Pasiniazid","f6","L8000-13","in 10mM DMSO","Bacterial","Microbiology","Pasiniazid(Paraniazide,Pasiniazide) is a composition of isoniazid and 4-aminosalicylic acid, used to treat tuberculosis patients.",290.27,"2066-89-9",{"v":58,"d":"58.00"},199.81,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/pasiniazid.html","C6H7N3O.C7H7NO3","Isonicotinic","Paraniazide,Pasiniazide","NNC(=O)C1=CC=NC=C1.NC2=CC(=C(C=C2)C(O)=O)O",{"v":-0.34,"d":"-0.340"},3,4,2]
["S4406","Pindolol","g6","L8000-13","in 10mM DMSO","5-HT Receptor","Others","N/A",248.32,"13523-86-9",{"v":50,"d":"50.00"},201.35,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/pindolol.html","C14H20N2O2","Free Base","N/A","CC(C)NCC(O)COC1=C2C=C[NH]C2=CC=C1",1.925,1,3,6]
["S4416","Trimipramine Maleate","h6","L8000-13","in 10mM DMSO","Others","Others","N/A",410.51,"521-78-8",{"v":82,"d":"82.00"},199.75,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/trimipramine-maleate.html","C24H30N2O4","maleate","N/A","CC(CN(C)C)CN1C2=C(CCC3=CC=CC=C13)C=CC=C2.OC(=O)\\C=C/C(O)=O",{"v":1.84,"d":"1.840"},2,0,6]
["S4502","Eltrombopag","a7","L8000-13","in 10mM DMSO","TpoR","Immunology & Inflammation","Eltrombopag (SB-497115), a member of the biarylhydrazone class, is a nonpeptide agonist of the thrombopoietin receptor (TpoR), used to treat chronic hepatitis C-associated thrombocytopenia and chronic immune (idiopathic) thrombocytopenia (ITP).",442.47,"496775-61-2",{"v":26,"d":"26.00"},58.76,"<1","N/A","http://selleckchem.com/products/eltrombopag.html","C25H22N4O4","Free Base","SB-497115","CC1=CC=C(C=C1C)N2N=C(C)C(=N/NC3=CC=CC(=C3O)C4=CC(=CC=C4)C(O)=O)/C2=O",4.702,4,2,5]
["S4504","6-Mercaptopurine (6-MP) Monohydrate","b7","L8000-13","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","6-Mercaptopurine (6-MP) Monohydrate is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.",170.19,"6112-76-1",{"v":34,"d":"34.00"},199.78,"<1","N/A","http://selleckchem.com/products/6-mercaptopurine-6-mp-monohydrate.html","C5H6N4OS","free base","N/A","O.S=C1N=CNC2=C1[NH]C=N2",{"v":0.16,"d":"0.160"},2,2,0]
["S4505","Vinblastine (NSC-49842) sulfate","c7","L8000-13","in 10mM DMSO","AChR,Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,Autophagy,Microtubule Associated","Cytoskeletal Signaling","Vinblastine sulfate (NSC49842, Vincaleukoblastine sulfate salt, 29060-LE, Exal, Velban, Velbe) inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM in a cell-free assay, used to treat certain kinds of cancer. Vinblastine sulfate induces autophagy and apoptosis.",909.05,"143-67-9",{"v":100,"d":"100.00"},{"v":110,"d":"110.00"},"<1","N/A","http://selleckchem.com/products/vinblastine-sulfate.html","C46H58N4O9.H2SO4","sulfate","Vincaleukoblastine sulfate salt, 29060-LE, Exal, Velban, Velbe","CCC1(O)CC2CN(CCC3=C([NH]C4=CC=CC=C34)C(C2)(C(=O)OC)C5=C(OC)C=C6N(C)C7C(O)(C(OC(C)=O)C8(CC)C=CCN9CCC7(C89)C6=C5)C(=O)OC)C1.O[S](O)(=O)=O",{"v":4.28,"d":"4.280"},7,1,10]
["S4506","Acetazolamide","d7","L8000-13","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Acetazolamide (Diamox), a potent carbonic anhydrase (CA) inhibitor, is commonly used in clinical practice as an immediate and readily available option for acute reduction of intraocular pressure(IOP).",222.25,"59-66-5",{"v":44,"d":"44.00"},197.98,"<1","N/A","http://selleckchem.com/products/acetazolamide.html","C4H6N4O3S2","free base","Diamox","CC(=O)NC1=NN=C(S1)[S](N)(=O)=O",-1.329,5,2,2]
["S4507","17-Hydroxyprogesterone","e7","L8000-13","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","17-Hydroxyprogesterone (17-OHP) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.",330.46,"68-96-2",{"v":66,"d":"66.00"},199.72,"<1","N/A","http://selleckchem.com/products/17-hydroxyprogesterone.html","C21H30O3","free base","N/A","CC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C",3.124,2,0,1]
["S4509","4-Aminoantipyrine","f7","L8000-13","in 10mM DMSO","COX","Immunology & Inflammation","4-Aminoantipyrine(Ampyrone) is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. It is used as a reagent for biochemical reactions producing peroxides or phenols.",203.24,"83-07-8",{"v":40,"d":"40.00"},196.81,{"v":40,"d":"40.00"},196.81,"http://selleckchem.com/products/4-aminoantipyrine.html","C11H13N3O","free base","Ampyrone, NSC 60242, Metapirazone, Solnapyrin-A, Solvapyrin-A,  Minoazophene, Aminoazophene,  Aminoantipyrin","CN1N(C2=CC=CC=C2)C(=O)C(=C1C)N",0.021,1,1,1]
["S4512","Aceglutamide","g7","L8000-13","in 10mM DMSO","Others","Others","Aceglutamide (α-N-Acetyl-L-glutamine, N2-Acetylglutamine) is a psychostimulant, nootropic agent which functions as a prodrug to glutamine with improved potency and stability.",188.18,"2490-97-3",{"v":37,"d":"37.00"},196.62,{"v":37,"d":"37.00"},196.62,"http://selleckchem.com/products/aceglutamide.html","C7H12N2O4","free base","α-N-Acetyl-L-glutamine, N2-Acetylglutamine","CC(=O)NC(CCC(N)=O)C(O)=O",-1.587,3,2,5]
["S4514","Acetylleucine","h7","L8000-13","in 10mM DMSO","Others","Others","Acetylleucine (N-acetyl-L-leucine) is a drug used in the treatment of vertigo.",173.21,"99-15-0",{"v":34,"d":"34.00"},196.29,"<1","N/A","http://selleckchem.com/products/acetylleucine.html","C8H15NO3","free base","N-acetyl-L-leucine","CC(C)CC(NC(C)=O)C(O)=O",0.571,2,1,4]
["S4516","(+)-Camphor","a8","L8000-13","in 10mM DMSO","Fungal,TRP Channel","Transmembrane Transporters","Camphor is a waxy, flammable, white or transparent solid with a strong aroma, often used to relieve pain, reduce itching and treat fungal infections. It can activate TRPV1  and TRPV3.",152.23,"464-49-3",{"v":30,"d":"30.00"},197.07,"<1","N/A","http://selleckchem.com/products/positive-rotation-camphor.html","C10H16O","free base","D-(+)-camphor, (1R)-(+)-camphor","CC1(C)C2CCC1(C)C(=O)C2",2.075,1,0,0]
["S4517","Cefotaxime sodium","b8","L8000-13","in 10mM DMSO","Antibiotics,Antibiotics for Plant Cell Culture,Bacterial","Microbiology","Cefotaxime sodium(HR-756) salt is a third-generation cephalosporin antibiotic; broad-spectrum antibiotic with activity against numerous Gram-positive and Gram-negative bacteria.",477.45,"64485-93-4",{"v":95,"d":"95.00"},198.97,{"v":95,"d":"95.00"},198.97,"http://selleckchem.com/products/cefotaxime-sodium.html","C16H17N5O7S2.Na","Sodium Salt","HR-756","[Na+].CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)COC(C)=O)C3=CSC(=N3)N",-2.384,7,2,8]
["S4521","DEET","c8","L8000-13","in 10mM DMSO","Anti-infection","Microbiology","DEET (N,N-Diethyl-meta-toluamide, diethyltoluamide) is a commen active ingredient insect repellent.",191.27,"134-62-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/deet.html","C12H17NO","free base","N,N-Diethyl-meta-toluamide, diethyltoluamide","CCN(CC)C(=O)C1=CC(=CC=C1)C",2.427,1,0,3]
["S4524","2-Ethoxybenzamide","d8","L8000-13","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","2-Ethoxybenzamide (Ethenzamide) is a common analgesic and anti-inflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains.",165.19,"938-73-8","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/2-ethoxybenzamide.html","C9H11NO2","Free Base","Ethenzamide","CCOC1=C(C=CC=C1)C(N)=O",1.164,2,1,3]
["S4526","Fenbufen","e8","L8000-13","in 10mM DMSO","COX","Neuronal Signaling","Fenbufen (Lederfen, CL-82204) is an orally active phenylalkanoic derivative with anti-inflammatory, analgesic and antipyretic activity. It is a non-steroidal anti-inflammatory drug.",254.28,"36330-85-5",{"v":50,"d":"50.00"},196.63,"<1","N/A","http://selleckchem.com/products/fenbufen.html","C16H14O3","free base","Lederfen, CL-82204","OC(=O)CCC(=O)C1=CC=C(C=C1)C2=CC=CC=C2",2.933,2,0,5]
["S4527","Fenofibric acid","f8","L8000-13","in 10mM DMSO","PPAR","Metabolism","Fenofibric acid (NSC 281318, Trilipix, FNF acid) is a fibrate that acts as a lipid-lowering agent, decreasing low-density lipoprotein cholesterol and triglycerides.",318.75,"42017-89-0",{"v":63,"d":"63.00"},197.65,{"v":63,"d":"63.00"},197.65,"http://selleckchem.com/products/fenofibric-acid.html","C17H15ClO4","free base","NSC 281318, Trilipix, FNF acid","CC(C)(OC1=CC=C(C=C1)C(=O)C2=CC=C(Cl)C=C2)C(O)=O",4.159,3,0,5]
["S4528","Furazolidone","g8","L8000-13","in 10mM DMSO","Bacterial","Microbiology","Furazolidone(Furoxone) is a synthetic nitrofuran derivative with bactericidal or bacteriostatic activity when used against Gram-positive and Gram-negative bacteria.",225.16,"67-45-8",{"v":45,"d":"45.00"},199.86,"<1","N/A","http://selleckchem.com/products/furazolidone.html","C8H7N3O5","free base","Furoxone","[O-][N+](=O)C1=CC=C(O1)\\C=N\\N2CCOC2=O",{"v":1.1,"d":"1.100"},4,0,3]
["S4534","6-Acetamidohexanoic acid","h8","L8000-13","in 10mM DMSO","Others","Others","6-Acetamidohexanoic acid (6-Acetamidocaproic acid) is a pharmaceutical intermediate.",173.21,"57-08-9","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/6-acetamidohexanoic-acid.html","C8H15NO3","Free Base","6-Acetamidocaproic acid","CC(=O)NCCCCCC(O)=O",0.337,2,1,6]
["S4535","Methylene Blue","a9","L8000-13","in 10mM DMSO","Dyes,Guanylate Cyclase,Microtubule Associated","GPCR & G Protein","Methylene Blue (Basic Blue 9, Tetramethylthionine chloride, methylthioninium chloride, CI-52015) is used as a dye in chromoendoscopy. It Inhibits tau filament formation with IC50 of 1.9μM. Also it inhibits soluble guanylyl cyclase.",319.85,"61-73-4",{"v":63,"d":"63.00"},196.97,{"v":63,"d":"63.00"},196.97,"http://selleckchem.com/products/methylene-blue.html","C16H18ClN3S","free base","Basic Blue 9, Tetramethylthionine chloride, methylthioninium chloride, CI-52015","[Cl-].CN(C)C1=CC2=C(C=C1)N=C3C=CC(C=C3S2)=[N+](C)C",0.369,1,0,1]
["S4538","Pantoprazole sodium","b9","L8000-13","in 10mM DMSO","ATPase,Proton Pump","Transmembrane Transporters","Pantoprazole (SKF96022, BY-1023) is a proton pump inhibitor drug that inhibits gastric acid secretion. It works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid.",405.35,"138786-67-1",{"v":81,"d":"81.00"},199.83,{"v":81,"d":"81.00"},199.83,"http://selleckchem.com/products/pantoprazole-sodium.html","C16H14F2N3NaO4S","Free Base","SKF96022 sodium, BY-1023 sodium","[Na+].COC1=CC=NC(=C1OC)C[S](=O)C2=NC3=C([N-]2)C=CC(=C3)OC(F)F",2.883,6,0,7]
["S4539","Salicylic acid","c9","L8000-13","in 10mM DMSO","COX","Neuronal Signaling","Salicylic acid (2-Hydroxybenzoic acid) is a beta hydroxy acid that occurs as a natural compound in plants which is an inhibitor of ethylene biosynthesis and cyclooxygenase activity.",138.12,"69-72-7",{"v":27,"d":"27.00"},195.48,"<1","N/A","http://selleckchem.com/products/salicylic-acid.html","C7H6O3","free base","2-Hydroxybenzoic acid","OC(=O)C1=C(O)C=CC=C1",1.217,1,1,1]
["S4541","Triclosan","d9","L8000-13","in 10mM DMSO","Bacterial","Microbiology","Triclosan (Irgasan, Cloxifenolum) is a diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.",289.54,"3380-34-5",{"v":57,"d":"57.00"},196.86,"<1","N/A","http://selleckchem.com/products/triclosan.html","C12H7Cl3O2","free base","Irgasan, Cloxifenolum","OC1=CC(=CC=C1OC2=CC=C(Cl)C=C2Cl)Cl",5.141,1,1,2]
["S4544","Urethane","e9","L8000-13","in 10mM DMSO","Bacterial","Microbiology","Urethane (Carbamic acid ethyl ester, Ethyl carbamate, Ethylurethane) is a kind of antineoplastic agent that is also used as a veterinary anesthetic. It is a intermediate in organic synthesis.",89.09,"51-79-6",{"v":17,"d":"17.00"},190.82,{"v":17,"d":"17.00"},190.82,"http://selleckchem.com/products/urethane.html","C3H7NO2","free base","Carbamic acid ethyl ester, Ethyl carbamate, Ethylurethane","CCOC(N)=O",0.159,2,1,2]
["S4546","Xylitol","f9","L8000-13","in 10mM DMSO","Autophagy","Autophagy","Xylitol (Adonitol, Ribitol, Xylite, D-Xylitol, Adonite) is a sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener.",152.15,"87-99-0",{"v":30,"d":"30.00"},197.17,{"v":30,"d":"30.00"},197.17,"http://selleckchem.com/products/xylitol.html","C5H12O5","free base","Adonitol, Ribitol, Xylite, D-Xylitol, Adonite","OCC(O)C(O)C(O)CO",{"v":-2.43,"d":"-2.430"},0,5,4]
["S4547","8-Hydroxyquinoline","g9","L8000-13","in 10mM DMSO","Bacterial","Microbiology","8-Hydroxyquinoline (8-Oxychinolin, 8-Quinolinol, Oxine) is an antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes.",145.16,"148-24-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/8-hydroxyquinoline.html","C9H7NO","Free Base","8-Oxychinolin, 8-Quinolinol, Oxine","OC1=CC=CC2=CC=CN=C12",1.774,1,1,0]
["S4548","Aminoguanidine hydrochloride","h9","L8000-13","in 10mM DMSO","NOS","Immunology & Inflammation","Aminoguanidine (Pimagedine, Guanyl hydrazine, Hydrazinecarboximidamide, Imino semicarbazide, Monoaminoguanidine) is a diamine oxidase and nitric oxide synthase inhibitor. It acts to reduce levels of advanced glycation end products (AGEs) through interacting with 3-deoxyglucosone.",110.55,"1937-19-5",{"v":22,"d":"22.00"},{"v":199,"d":"199.00"},{"v":22,"d":"22.00"},{"v":199,"d":"199.00"},"http://selleckchem.com/products/aminoguanidine-hydrochloride.html","CH6N4.HCl","hydrochloride","Pimagedine, Guanyl hydrazine, Hydrazinecarboximidamide, Imino semicarbazide, Monoaminoguanidine","Cl.NNC(N)=N",-1.098,0,3,1]
["S4550","Azelaic acid","a10","L8000-13","in 10mM DMSO","Bacterial","Microbiology","Azelaic acid (Nonanedioic acid, Finacea, Azelex, Anchoic acid) is an organic compound produced by the ozonolysis of oleic acid and possesses antibacterial, keratolytic, comedolytic, and anti-oxidant activity.",188.22,"123-99-9",{"v":37,"d":"37.00"},196.58,{"v":37,"d":"37.00"},196.58,"http://selleckchem.com/products/azelaic-acid.html","C9H16O4","free base","Nonanedioic acid, Finacea, Azelex, Anchoic acid","OC(=O)CCCCCCCC(O)=O",1.921,2,0,8]
["S4552","Bithionol","b10","L8000-13","in 10mM DMSO","cAMP","GPCR & G Protein","Bithionol (Actamer) is a potent inhibitor of soluble adenylyl cyclase(sAC) with an IC50 of 4 μM and has antibacterial and anthelmintic properties along with algaecide activity.",356.05,"97-18-7",{"v":71,"d":"71.00"},199.41,"<1","N/A","http://selleckchem.com/products/bithionol.html","C12H6Cl4O2S","free base","Actamer","OC1=C(Cl)C=C(Cl)C=C1SC2=C(O)C(=CC(=C2)Cl)Cl",6.122,0,2,2]
["S4561","Danthron","c10","L8000-13","in 10mM DMSO","AMPK","PI3K/Akt/mTOR","Danthron (Chrysazin, Antrapurol) functions in regulating glucose and lipid metabolism by activating AMPK. Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron used to be a laxativa and now is currently used as an antioxidant in synthetic lubricants, in the synthesis of experimental antitumor agents, as a fungicide and as an intermediate for making dyes.",240.21,"117-10-2",{"v":4,"d":"4.00"},16.65,"<1","N/A","http://selleckchem.com/products/danthron.html","C14H8O4","free base","chrysazin, Antrapurol","OC1=CC=CC2=C1C(=O)C3=C(O)C=CC=C3C2=O",2.324,2,2,0]
["S4564","Diethylcarbamazine citrate","d10","L8000-13","in 10mM DMSO","Parasite","Microbiology","Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria and is highly specific for several parasites and does not contain any toxic metallic elements.",391.42,"1642-54-2",{"v":78,"d":"78.00"},199.27,{"v":78,"d":"78.00"},199.27,"http://selleckchem.com/products/diethylcarbamazine-citrate.html","C10H21N3O.C6H8O7","citrate","N/A","CCN(CC)C(=O)N1CCN(C)CC1.OC(=O)CC(O)(CC(O)=O)C(O)=O",-3.918,4,0,7]
["S4569","Fluphenazine dihydrochloride","e10","L8000-13","in 10mM DMSO","Dopamine Receptor","GPCR & G Protein","Fluphenazine dihydrochloride (Prolixin) is a phenothiazine-class D1DR and D2DR inhibitor. It also inhibits  Histamine H1 Receptor.",510.44,"146-56-5",{"v":100,"d":"100.00"},195.91,{"v":100,"d":"100.00"},195.91,"http://selleckchem.com/products/fluphenazine-dihydrochloride.html","C22H26F3N3OS.2HCl","dihydrochloride","Prolixin","Cl.Cl.OCCN1CCN(CCCN2C3=C(SC4=CC=C(C=C24)C(F)(F)F)C=CC=C3)CC1",5.199,0,1,7]
["S4570","Halothane","f10","L8000-13","in 10mM DMSO","Others","Others","Halothane (Narcotane) is a general inhalation anesthetic used for induction and maintenance of general anesthesia.",197.38,"151-67-7","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/halothane.html","C2HBrClF3","free base","Narcotane","FC(F)(F)C(Cl)Br",2.509,0,0,1]
["S4571","Hexylresorcinol","g10","L8000-13","in 10mM DMSO","Tyrosinase","Proteases","Hexylresorcinol (4-Hexylresorcinol) is an organic compound with local anaesthetic, antiseptic and anthelmintic properties, is a potent inhibitor of mushroom tyrosinase. The IC50 values of hexylresorcinol for monophenolase is 1.24 μM and for diphenolase is 0.85 μM.",194.27,"136-77-6",{"v":38,"d":"38.00"},{"v":195.6,"d":"195.60"},"<1","N/A","http://selleckchem.com/products/hexylresorcinol.html","C12H18O2","free base","4-Hexylresorcinol","CCCCCCC1=C(O)C=C(O)C=C1",4.113,0,2,5]
["S4576","Sulfabenzamide","h10","L8000-13","in 10mM DMSO","Bacterial","Microbiology","Sulfabenzamide (Sultrin, N-Sulfanilylbenzamide) is an antibacterial/antimicrobial which also exhibit their antitumor effects through multiple mechanisms including inhibition of membrane bound carbonic anhydrases, prevention of microtubule assembly, cell cycle arrest, and inhibition of angiogenesis.",276.31,"127-71-9",{"v":55,"d":"55.00"},199.05,"<1","N/A","http://selleckchem.com/products/sulfabenzamide.html","C13H12N2O3S","free base","Sultrin, N-Sulfanilylbenzamide","NC1=CC=C(C=C1)[S](=O)(=O)NC(=O)C2=CC=CC=C2",1.442,3,2,3]
["S4578","Tyloxapol","a11","L8000-13","in 10mM DMSO","Others","Others","Tyloxapol (Triton WR1339) is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surfactant to aid liquefaction, removal of mucopurulent and bronchopulmonary secretions. It also blocks plasma lipolytic activity, and thus the breakdown of triglyceride-rich lipoproteins.","N/A","25301-02-4","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/tyloxapol.html","(C14H22O.C2H4O.CH2O)x","free base","Triton WR1339","CC1=CC(=CC(=C1OCCO)CC2=C(OCCO)C(=CC(=C2)C(C)(C)CC(C)(C)C)CC3=C(OCCO)C=CC(=C3)C(C)(C)CC(C)(C)C)C(C)(C)CC(C)(C)C",{"v":16.58,"d":"16.580"},3,3,22]
["S4583","Butamben","b11","L8000-13","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.",193.24,"94-25-7",{"v":38,"d":"38.00"},196.65,{"v":38,"d":"38.00"},196.65,"http://selleckchem.com/products/butamben.html","C11H15NO2","free base","Butyl 4-aminobenzoate","CCCCOC(=O)C1=CC=C(N)C=C1",2.267,2,1,5]
["S4585","Succinylsulfathiazole","c11","L8000-13","in 10mM DMSO","Antibiotics","Microbiology","Succinylsulfathiazole (Succinylsulphathiazole), a sulfonamide, is an antibiotic.",355.39,"116-43-8",{"v":71,"d":"71.00"},199.78,"<1","N/A","http://selleckchem.com/products/succinylsulfathiazole.html","C13H13N3O5S2","free base","Succinylsulphathiazole","OC(=O)CCC(=O)NC1=CC=C(C=C1)[S](=O)(=O)NC2=NC=CS2",{"v":0.28,"d":"0.280"},5,2,7]
["S4587","Pentylenetetrazol","d11","L8000-13","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Pentylenetetrazol (Pentylenetetrazole, Metrazole, pentetrazol, pentamethylenetetrazol, Corazol, Cardiazol, PTZ) displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GABA(A) receptor antagonist.",138.17,"54-95-5",{"v":27,"d":"27.00"},195.41,{"v":27,"d":"27.00"},195.41,"http://selleckchem.com/products/pentylenetetrazol.html","C6H10N4","Free Base","Pentylenetetrazole, Metrazole, pentetrazol, pentamethylenetetrazol, Corazol, Cardiazol, PTZ","C1CC[N]2N=NN=C2CC1",0.568,3,0,0]
["S4589","Amodiaquine dihydrochloride dihydrate","e11","L8000-13","in 10mM DMSO","Histone Methyltransferase,HNMT,Transferase","Epigenetics","Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase with estimated Ki of 18.6 nM. It is also used as an antimalarial and anti-inflammatory agent.",464.81,"6398-98-7",{"v":92,"d":"92.00"},197.93,{"v":29,"d":"29.00"},62.39,"http://selleckchem.com/products/amodiaquine-dihydrochloride-dihydrate.html","C20H22ClN3O.2HCl.2H2O","dihydrochloride dihydrate","N/A","O.O.Cl.Cl.CCN(CC)CC1=CC(=CC=C1O)NC2=C3C=CC(=CC3=NC=C2)Cl",5.109,1,2,6]
["S4591","Nitroxoline","f11","L8000-13","in 10mM DMSO","Cathepsin B,Cysteine Protease","Proteases","Nitroxoline (8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol, 5-Nitro-8-hydroxyquinoline) is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. Nitroxoline impairs tumor progression in vitro and in vivo by inhibiting cathepsin B activity.",190.16,"4008-48-4",{"v":38,"d":"38.00"},199.83,"<1","N/A","http://selleckchem.com/products/nitroxoline.html","C9H6N2O3","free base","8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol, 5-Nitro-8-hydroxyquinoline","OC1=CC=C(C2=CC=CN=C12)[N+]([O-])=O",1.668,1,1,1]
["S4593","Chlormadinone acetate","g11","L8000-13","in 10mM DMSO","5-alpha Reductase,Androgen Receptor","Endocrinology & Hormones","Chlormadinone acetate (Gestafortin) is a steroidal progestin with additional antiandrogen and antigonadotropic effects, used often in combinations as an oral contraceptive. Its half-life is about 34-38 hours.",404.93,"302-22-7",{"v":27,"d":"27.00"},66.68,"<1","N/A","http://selleckchem.com/products/chlormadinone-acetate.html","C23H29ClO4","free base","Gestafortin","CC(=O)OC1(CCC2C3C=C(Cl)C4=CC(=O)CCC4(C)C3CCC12C)C(C)=O",3.428,4,0,3]
["S4594","Cephalothin sodium","h11","L8000-13","in 10mM DMSO","Antibiotics,Antibiotics for Mammalian Cell Culture,Bacterial","Microbiology","Cephalothin (Cefalotin, Cephalotin) sodium is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.",418.42,"58-71-9",{"v":10,"d":"10.00"},{"v":23.9,"d":"23.90"},{"v":83,"d":"83.00"},198.37,"http://selleckchem.com/products/cephalothin.html","C16H15N2NaO6S2","sodium","Cefalotin sodium, Sodium cephalotin","[Na+].CC(=O)OCC1=C(N2C(SC1)C(NC(=O)CC3=CC=CS3)C2=O)C([O-])=O",-1.067,4,1,7]
["S4595","Cefazolin Sodium","a2","L8000-14","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Cefazolin Sodium (cefazoline, cephazolin, Ancef) is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.",476.49,"27164-46-1",{"v":95,"d":"95.00"},199.37,{"v":95,"d":"95.00"},199.37,"http://selleckchem.com/products/cefazolin-sodium.html","C14H14N8O4S3.Na","sodium","cefazoline sodium, cephazolin sodium, Ancef","[Na+].CC1=NN=C(SCC2=C(N3C(SC2)C(NC(=O)C[N]4C=NN=N4)C3=O)C([O-])=O)S1",-2.807,7,1,7]
["S4596","Cefixime","b2","L8000-14","in 10mM DMSO","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Bacterial","Microbiology","Cefixime (Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635) is an antibiotic useful for the treatment of a number of bacterial infections. It is a third generation cephalosporin.",453.45,"79350-37-1",{"v":90,"d":"90.00"},198.48,"<1","N/A","http://selleckchem.com/products/cefixime.html","C16H15N5O7S2","free base","Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635","NC1=NC(=CS1)C(=N/OCC(O)=O)/C(=O)NC2C3SCC(=C(N3C2=O)C(O)=O)C=C",-0.651,7,2,8]
["S4599","Benzyl benzoate","c2","L8000-14","in 10mM DMSO","Parasite","Microbiology","Benzyl benzoate (Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester) is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.",212.24,"120-51-4","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/benzyl-benzoate.html","C14H12O2","free base","Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester","O=C(OCC1=CC=CC=C1)C2=CC=CC=C2",3.268,2,0,4]
["S4600","Benzyl alcohol","d2","L8000-14","in 10mM DMSO","Others","Others","Benzyl alcohol (Phenylmethanol, Benzenemethanol, Phenylcarbinol, Benzoyl alcohol) is used as a local anesthetic. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.",108.14,"100-51-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/benzyl-alcohol.html","C7H8O","free base","Phenylmethanol, Benzenemethanol, Phenylcarbinol, Benzoyl alcohol","OCC1=CC=CC=C1",1.225,0,1,1]
["S4601","Clioquinol","e2","L8000-14","in 10mM DMSO","Fungal","Microbiology","Clioquinol is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.",{"v":305.5,"d":"305.50"},"130-26-7",{"v":61,"d":"61.00"},199.67,"<1","N/A","http://selleckchem.com/products/5-chloro-8-hydroxy-7-iodoquinoline.html","C9H5ClINO","free base","Iodochlorhydroxyquin, Chinoform","OC1=C(I)C=C(Cl)C2=CC=CN=C12",3.016,1,1,0]
["S4602","Acetohydroxamic acid","f2","L8000-14","in 10mM DMSO","Bacterial","Microbiology","Acetohydroxamic acid (N-Hydroxyacetamide, Methylhydroxamic acid, Acetic acid|oxime, Lithostat,AHA) is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.",75.07,"546-88-3",{"v":15,"d":"15.00"},199.81,{"v":15,"d":"15.00"},199.81,"http://selleckchem.com/products/acetohydroxamic-acid.html","C2H5NO2","free base","N-Hydroxyacetamide, Methylhydroxamic acid, Acetic acid|oxime, Lithostat,AHA","CC(=O)NO",{"v":-0.82,"d":"-0.820"},1,1,0]
["S4603","Gallic acid","g2","L8000-14","in 10mM DMSO","ROS","Immunology & Inflammation","Gallic acid (3,4,5-Trihydroxybenzoic acid, Gallate, Benzoic acid), known as powerful antioxidants, is an organic acid found in a variety of foods and herbs.",170.12,"149-91-7",{"v":34,"d":"34.00"},199.86,{"v":7,"d":"7.00"},41.15,"http://selleckchem.com/products/gallic-acid.html","C7H6O5","free base","3,4,5-Trihydroxybenzoic acid, Gallate, Benzoic acid","OC(=O)C1=CC(=C(O)C(=C1)O)O",0.733,1,3,1]
["S4604","Levofloxacin hydrate","h2","L8000-14","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Levofloxacin (Levaquin, Tavanic, Quixin, Iquix, Cravit) is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. It acts by inhibiting DNA gyrase (bacterial topoisomerase II).",370.38,"138199-71-0",{"v":74,"d":"74.00"},199.79,{"v":5,"d":"5.00"},{"v":13.5,"d":"13.50"},"http://selleckchem.com/products/levofloxacin-hydrate.html","C18H20FN3O4.1/2H2O","hydrate","Levofloxacin hemihydrate, Levaquin hydrate, Tavanic hydrate, Quixin hydrate, Iquix hydrate, Cravit hydrate","CC1COC2=C3N1C=C(C(O)=O)C(=O)C3=CC(=C2N4CCN(C)CC4)F",{"v":-0.64,"d":"-0.640"},3,0,2]
["S4609","Diflunisal","a3","L8000-14","in 10mM DMSO","COX","Neuronal Signaling","Diflunisal (Dolobid, Dolobis, Flovacil, Fluniget,MK-647) is a difluorophenyl derivate of salicylic acid and a nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic and anti-inflammatory properties. The mechanism of action of diflunisal is as a Cyclooxygenase Inhibitor.",{"v":250.2,"d":"250.20"},"22494-42-4",{"v":50,"d":"50.00"},199.84,"<1","N/A","http://selleckchem.com/products/diflunisal.html","C13H8F2O3","free base","Dolobid, Dolobis, Flovacil, Fluniget,MK-647","OC(=O)C1=C(O)C=CC(=C1)C2=C(F)C=C(F)C=C2",3.147,1,1,2]
["S4610","Mebendazole","b3","L8000-14","in 10mM DMSO","Parasite","Microbiology","Mebendazole (Vermox, Telmin, Pantelmin, Mebenvet) is a synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake.",295.29,"31431-39-7",{"v":6,"d":"6.00"},20.32,"<1","N/A","http://selleckchem.com/products/mebendazole.html","C16H13N3O3","free base","Vermox, Telmin, Pantelmin, Mebenvet","COC(=O)NC1=NC2=C([NH]1)C=CC(=C2)C(=O)C3=CC=CC=C3",3.055,4,2,4]
["S4619","Itopride hydrochloride","c3","L8000-14","in 10mM DMSO","AChR","Neuronal Signaling","Itopride hydrochloride (Ganaton, HSR803) is an AChE inhibitor. The IC50 of itopride with AChE is 2.04 +/- 0.27 μM.",394.89,"122892-31-3",{"v":78,"d":"78.00"},197.52,{"v":78,"d":"78.00"},197.52,"http://selleckchem.com/products/itopride-hydrochloride.html","C20H26N2O4.HCl","hydrochloride","Ganaton, HSR803","Cl.COC1=CC=C(C=C1OC)C(=O)NCC2=CC=C(OCCN(C)C)C=C2",3.093,4,1,9]
["S4625","Alcaftadine","d3","L8000-14","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Alcaftadine (Lastacaft, R89674) is a high affinity ligand for the H1 receptor, with a pKi (8.5) that is comparable with that of other H1 antihistamines. Alcaftadine is also an antagonist for H2 and H4 receptors with no affinity for the H3 receptor.",307.39,"147084-10-4",{"v":28,"d":"28.00"},91.09,"<1","N/A","http://selleckchem.com/products/alcaftadine.html","C19H21N3O","free base","Lastacaft, R89674","CN1CCC(CC1)=C2C3=C(CC[N]4C(=CN=C24)C=O)C=CC=C3",2.831,2,0,1]
["S4628","(+/-)-Sulfinpyrazone","e3","L8000-14","in 10mM DMSO","COX","Neuronal Signaling","Sulfinpyrazone (G-28315, NSC 75925) is one of the most studied platelet COX inhibitors, also a uricosuric agent that competitively inhibits uric acid reabsorption in kidney proximal tubules.",404.48,"57-96-5",{"v":80,"d":"80.00"},197.78,"<1","N/A","http://selleckchem.com/products/sulfinpyrazone.html","C23H20N2O3S","free base","G-28315, NSC 75925","O=C1C(CC[S](=O)C2=CC=CC=C2)C(=O)N(N1C3=CC=CC=C3)C4=CC=CC=C4",3.434,3,0,6]
["S4629","Chlorotrianisene","f3","L8000-14","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Chlorotrianisene (tri-p-anisylchloroethylene, TACE, CTA) is a synthetic, non-steroidal estrogen. It is a selective estrogen receptor modulator.",380.86,"569-57-3",{"v":76,"d":"76.00"},199.55,"<1","N/A","http://selleckchem.com/products/chlorotrianisene.html","C23H21ClO3","free base","tri-p-anisylchloroethylene, tris(p-methoxyphenyl)chloroethylene, TACE, CTA","COC1=CC=C(C=C1)C(Cl)=C(C2=CC=C(OC)C=C2)C3=CC=C(OC)C=C3",5.614,3,0,6]
["S4630","Diazoxide","g3","L8000-14","in 10mM DMSO","ADC Cytotoxin,Potassium Channel","Transmembrane Transporters","Diazoxide (Sch-6783, SRG-95213, Proglycem) is a well-known small molecule that activates KATP channels in the smooth muscle of blood vessels and pancreatic beta-cells by increasing membrane permeability to potassium ions.",230.67,"364-98-7",{"v":46,"d":"46.00"},199.42,"<1","N/A","http://selleckchem.com/products/diazoxide.html","C8H7ClN2O2S","free base","Sch-6783, SRG-95213, Proglycem","CC1=NC2=CC=C(Cl)C=C2[S](=O)(=O)N1",1.196,3,1,0]
["S4633","Isosorbide Mononitrate","h3","L8000-14","in 10mM DMSO","Others","Others","Isosorbide mononitrate (Elantan, Monoket, Mononit, Imdur, Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.",191.14,"16051-77-7",{"v":38,"d":"38.00"},198.81,{"v":38,"d":"38.00"},198.81,"http://selleckchem.com/products/isosorbide-mononitrate.html","C6H9NO6","Free Base","Isosorbide-5-mononitrate, Elantan, Monoket, Mononit, Imdur, Corangin","OC1COC2C(COC12)O[N+]([O-])=O",1.003,3,1,2]
["S4635","Cyproheptadine hydrochloride sesquihydrate","a4","L8000-14","in 10mM DMSO","5-HT Receptor,SETD","Neuronal Signaling","Cyproheptadine hydrochloride (Periactin, Peritol) is non-selective 5HT2 antagonist with IC50 of 0.6 nM. Also a SETD7/9 inhibitor.",350.88,"41354-29-4",{"v":70,"d":"70.00"},{"v":199.5,"d":"199.50"},"<1","N/A","https://www.selleckchem.com/products/cyproheptadine-hydrochloride-sesquihydrate.html","C21H21N.HCl.3/2H2O","hydrochloride sesquihydrate","Periactin hydrochloride, Peritol","O.O.O.Cl.Cl.CN1CCC(CC1)=C2C3=CC=CC=C3C=CC4=CC=CC=C24.CN5CCC(CC5)=C6C7=CC=CC=C7C=CC8=CC=CC=C68",5.478,0,0,0]
["S4641","Tedizolid Phosphate","c4","L8000-14","in 10mM DMSO","Antibiotics","Microbiology","Tedizolid (TR-701FA) is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.",450.32,"856867-55-5",{"v":22,"d":"22.00"},48.85,"<1","N/A","http://selleckchem.com/products/tedizolid-phosphate.html","C17H16FN6O6P","free base","TR-701FA","C[N]1N=NC(=N1)C2=NC=C(C=C2)C3=CC=C(C=C3F)N4CC(CO[P](O)(O)=O)OC4=O",1.712,7,0,6]
["S4646","Ciclesonide","d4","L8000-14","in 10mM DMSO","COVID-19,Glucocorticoid Receptor","Endocrinology & Hormones","Ciclesonide (Alvesco, Omnaris, RPR251526, Zetonna) is a glucocorticoid used to treat obstructive airway diseases.",540.69,"126544-47-6",{"v":100,"d":"100.00"},184.95,"<1","N/A","http://selleckchem.com/products/ciclesonide.html","C32H44O7","free base","Alvesco, Omnaris, RPR251526, Zetonna","CC(C)C(=O)OCC(=O)C12OC(OC1CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC23C)C6CCCCC6",4.696,6,1,6]
["S4647","Cefmenoxime hydrochloride","e4","L8000-14","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Cefmenoxime (SCE-1365), a potent inhibitor of Enterobacteriaceae, is a cephalosporin antibiotic that is administered intravenously or intramuscularly.",1059.58,"75738-58-8",{"v":70,"d":"70.00"},66.06,"<1","N/A","http://selleckchem.com/products/cefmenoxime-hydrochloride.html","C32H34N18O10S6.HCl","hydrochloride","Cefmenoxime hemihydrochloride, SCE-1365 hemihydrochloride","Cl.CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)CSC3=NN=N[N]3C)C4=CSC(=N4)N.CO\\N=C(/C(=O)NC5C6SCC(=C(N6C5=O)C(O)=O)CSC7=NN=N[N]7C)C8=CSC(=N8)N",-1.031,18,4,16]
["S4650","Atipamezole","f4","L8000-14","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Atipamezole (MPV-1248, MPV1248, Antisedan) is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug.",212.29,"104054-27-5",{"v":42,"d":"42.00"},197.84,"<1","N/A","http://selleckchem.com/products/atipamezole.html","C14H16N2","Free Base","MPV-1248, MPV1248, MPV 1248, Antisedan","CCC1(CC2=C(C1)C=CC=C2)C3=CN=C[NH]3",3.012,1,1,2]
["S4651","Etoricoxib","g4","L8000-14","in 10mM DMSO","COX","Neuronal Signaling","Etoricoxib (Arcoxia, MK-663, MK-0663, Tauxib, Algix, Nucoxia) is a new COX-2 selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties.",358.84,"202409-33-4",{"v":71,"d":"71.00"},197.86,"<1","N/A","http://selleckchem.com/products/etoricoxib.html","C18H15ClN2O2S","free base","Arcoxia, MK-663, MK-0663, Tauxib, Algix, Nucoxia","CC1=NC=C(C=C1)C2=NC=C(Cl)C=C2C3=CC=C(C=C3)[S](C)(=O)=O",3.467,4,0,3]
["S4656","Parecoxib","h4","L8000-14","in 10mM DMSO","COX","Neuronal Signaling","Parecoxib (SC-69124, Valus-P, Vorth-P) is a selective COX2 inhibitor.",370.42,"198470-84-7",{"v":74,"d":"74.00"},199.77,"<1","N/A","http://selleckchem.com/products/parecoxib.html","C19H18N2O4S","free base","SC-69124, Valus-P, Vorth-P","CCC(=O)N[S](=O)(=O)C1=CC=C(C=C1)C2=C(C)ON=C2C3=CC=CC=C3",3.256,5,1,5]
["S4658","Hydroquinidine","a5","L8000-14","in 10mM DMSO","Others","Others","Hydroquinidine (Dihydroquinidine, Hydroconchinine, Hydroconquinine, Dihydroquinine) is an antiarrhythmic agent.",326.43,"1435-55-8",{"v":65,"d":"65.00"},199.12,"<1","N/A","http://selleckchem.com/products/hydroquinidine.html","C20H26N2O2","free base","Dihydroquinidine, Hydroconchinine, Hydroconquinine, Dihydroquinine","CCC1CN2CCC1CC2C(O)C3=C4C=C(OC)C=CC4=NC=C3",3.124,2,1,4]
["S4660","Glycopyrrolate","b5","L8000-14","in 10mM DMSO","AChR","Neuronal Signaling","Glycopyrrolate (Glycopyrronium, Robinul, Gastrodyn) is a muscarinic antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with some anesthetics.",398.33,"596-51-0",{"v":65,"d":"65.00"},163.18,{"v":79,"d":"79.00"},198.33,"http://selleckchem.com/products/glycopyrrolate.html","C19H28NO3.Br","bromide","Glycopyrrolate bromide, Glycopyrronium bromide, Robinul, Gastrodyn","[Br-].C[N+]1(C)CCC(C1)OC(=O)C(O)(C2CCCC2)C3=CC=CC=C3",-0.961,2,0,5]
["S4662","Atazanavir","c5","L8000-14","in 10mM DMSO","HIV Protease,P450 (e.g. CYP17),P-gp","Proteases","Atazanavir (Latazanavir, Zrivada, Reyataz, BMS-232632) is an azapeptide and HIV-protease inhibitor that is used in the treatment of HIV infections and AIDS in combination with other anti-HIV agents. Atazanavir is a substrate and inhibitor of cytochrome P450 isozyme 3A (CYP3A4) and an inhibitor and inducer of P-glycoprotein.",704.86,"198904-31-3",{"v":71,"d":"71.00"},100.73,"<1","N/A","http://selleckchem.com/products/atazanavir-reyataz.html","C38H52N6O7","free base","Latazanavir, Zrivada, Reyataz, BMS-232632","COC(=O)NC(C(=O)NC(CC1=CC=CC=C1)C(O)CN(CC2=CC=C(C=C2)C3=NC=CC=C3)NC(=O)C(NC(=O)OC)C(C)(C)C)C(C)(C)C",{"v":4.69,"d":"4.690"},7,5,18]
["S4665","Rabeprazole sodium","d5","L8000-14","in 10mM DMSO","Proton Pump","Transmembrane Transporters","Rabeprazole (Aciphex, Dexrabeprazole, Habeprazole) is an antiulcer drug in the class of proton pump inhibitors.",381.42,"117976-90-6",{"v":76,"d":"76.00"},199.26,{"v":76,"d":"76.00"},199.26,"https://www.selleckchem.com/products/rabeprazole-sodium.html","C18H20N3O3S.Na","sodium salt","Aciphex Sodium, Dexrabeprazole Sodium, Habeprazole Sodium","COCCCOC1=C(C)C(=NC=C1)C[S](=O)C2=NC3=CC=CC=C3[N]2[Na]",{"v":2.47,"d":"2.470"},5,0,8]
["S4666","Sivelestat sodium tetrahydrate","e5","L8000-14","in 10mM DMSO","Serine Protease","Proteases","Sivelestat sodium tetrahydrate (ONO5046-Na, EI546, LY544349) is a competitive inhibitor of human neutrophil elastase, also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse.",528.51,"201677-61-4",{"v":100,"d":"100.00"},189.21,"<1","N/A","http://selleckchem.com/products/sivelestat-sodium.html","C20H21N2O7S.4H2O.Na","sodium salt","Sivelestat sodium, ONO5046-Na, Sodium sivelestat, EI546 sodium, LY544349 sodium","O.O.O.O.[Na+].CC(C)(C)C(=O)OC1=CC=C(C=C1)[S](=O)(=O)NC2=CC=CC=C2C(=O)NCC([O-])=O",0.018,5,2,9]
["S4667","Lidocaine hydrochloride","f5","L8000-14","in 10mM DMSO","EGFR","Angiogenesis","Lidocaine hydrochloride (Lidothesin, Lignocaine, Xyloneural) is an inhibitor of epidermal growth factor receptor (EGFR) and has antiproliferative effect on human tongue cancer cells. Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmia agent.",{"v":270.8,"d":"270.80"},"73-78-9",{"v":54,"d":"54.00"},199.41,{"v":54,"d":"54.00"},199.41,"http://selleckchem.com/products/lidocaine-hydrochloride.html","C14H22N2O.HCl","hydrochloride","Lidocaine HCL, Lidothesin, Lignocaine hydrochloride, Xyloneural","Cl.CCN(CC)CC(=O)NC1=C(C)C=CC=C1C",3.008,1,1,5]
["S4669","Benzocaine hydrochloride","g5","L8000-14","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Benzocaine hydrochloride (Ethyl 4-aminobenzoate, Ethyl p-aminobenzoate) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.",201.65,"23239-88-5",{"v":40,"d":"40.00"},198.36,"<1","N/A","http://selleckchem.com/products/benzocaine-hydrochloride.html","C9H11NO2.HCl","hydrochloride","Ethyl 4-aminobenzoate hydrochloride, Benzocaine HCl, Ethyl p-aminobenzoate hydrochloride","Cl.CCOC(=O)C1=CC=C(N)C=C1",1.669,2,1,3]
["S4672","Dimenhydrinate","h5","L8000-14","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Dimenhydrinate is an over-the-counter drug used to prevent nausea, vomiting, and dizziness caused by motion sickness.",469.96,"523-87-5",{"v":94,"d":"94.00"},200.02,"<1","N/A","http://www.selleck.cn/products/dimenhydrinate.html","C24H28ClN5O3","Free Base","N/A","CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.CN3C(=O)N(C)C4=C([NH]C(=N4)Cl)C3=O",3.955,4,1,6]
["S4673","Etonogestrel","a6","L8000-14","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Etonogestrel (Implanon, Nexplanon, 3-Oxodesogestrel, 3-keto-Desogestrel) is a synthetic form of the naturally occurring female sex hormone progesterone. It binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor mediated gene expression.",324.46,"54048-10-1",{"v":64,"d":"64.00"},197.25,"<1","N/A","http://selleckchem.com/products/etonogestrel.html","C22H28O2","free base","Implanon, Nexplanon, 3-Oxodesogestrel, 3-keto-Desogestrel","CCC12CC(=C)C3C(CCC4=CC(=O)CCC34)C1CCC2(O)C#C",4.827,1,0,1]
["S4679","Terazosin HCl","b6","L8000-14","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Terazosin (Hytrin, Zayasel, Terazosine, Flumarc, Fosfomic, Blavin) is a selective alpha-1 antagonist used for treatment of symptoms of an enlarged prostate (BPH). It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls.",423.89,"63074-08-8",{"v":84,"d":"84.00"},198.16,{"v":1,"d":"1.00"},2.36,"http://selleckchem.com/products/terazosin.html","C19H25N5O4.HCl","hydrochloride","Hytrin, Zayasel, Terazosine, Flumarc, Fosfomic, Blavin","Cl.COC1=CC2=C(C=C1OC)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N",1.762,6,1,4]
["S4682","Loxoprofen","d6","L8000-14","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Loxoprofen (Koloxo, Loxoprofene, Loxoprofeno) is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group.",{"v":246.3,"d":"246.30"},"68767-14-6",{"v":49,"d":"49.00"},198.94,"<1","N/A","http://selleckchem.com/products/loxoprofen.html","C15H18O3","free base","Koloxo, Loxoprofene, Loxoprofeno","CC(C(O)=O)C1=CC=C(CC2CCCC2=O)C=C1",2.936,2,0,4]
["S4685","Efavirenz","e6","L8000-14","in 10mM DMSO","Reverse Transcriptase","Microbiology","Efavirenz (Sustiva, Stocrin, DMP-266) is a synthetic non-nucleoside reverse transcriptase (RT) inhibitor with antiviral activity.",315.67,"154598-52-4",{"v":63,"d":"63.00"},199.58,"<1","N/A","http://selleckchem.com/products/efavirenz.html","C14H9ClF3NO2","free base","Sustiva, Stocrin, DMP-266, DMP 266","FC(F)(F)C1(OC(=O)NC2=C1C=C(Cl)C=C2)C#CC3CC3",4.381,2,1,3]
["S4686","Vitamin E","f6","L8000-14","in 10mM DMSO","COX,VEGFR","Neuronal Signaling","Vitamin E (D-alpha-Tocopherol) is a fat-soluble vitamin with potent antioxidant properties. It is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription.",430.71,"59-02-9","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/vitamin-e.html","C29H50O2","free base","Alpha-Tocopherol, D-alpha-Tocopherol, 5,7,8-Trimethyltocol|(+)-alpha-Tocopherol","CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=C(C)C(=C(C)C(=C2O1)C)O",{"v":10.44,"d":"10.440"},1,1,12]
["S4687","Rivastigmine","g6","L8000-14","in 10mM DMSO","AChR","Neuronal Signaling","Rivastigmine (SDZ-ENA 713, Exelon) is a cholinesterase inhibitor with IC50 of 5.5 μM. It inhibits acetylcholinesterase (IC50 = 4.15 µM) and butyrylcholinesterase (IC50 = 37 nM).",250.34,"123441-03-2","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/rivastigmine.html","C14H22N2O2","free base","SDZ-ENA 713, Exelon","CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C",2.599,2,0,5]
["S4690","Escin","h6","L8000-14","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Escin (Aescin) is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum(the horse chestnut).",1131.26,"6805-41-0",{"v":66,"d":"66.00"},58.34,"<1","N/A","http://selleckchem.com/products/escin.html","C55H86O24","free base","Aescin","C\\C=C(C)/C(=O)OC1C(OC(C)=O)C2(CO)C(O)CC3(C)C(=CCC4C5(C)CCC(OC6OC(C(OC7OC(CO)C(O)C(O)C7O)C(O)C6OC8OC(CO)C(O)C(O)C8O)C(O)=O)C(C)(CO)C5CCC34C)C2CC1(C)C",-0.723,11,12,16]
["S4693","Guanfacine Hydrochloride","a7","L8000-14","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Guanfacine Hydrochloride (Tenex, Intuniv) is a selective α2A-adrenoceptor agonist with anti-hypertensive effect.",282.55,"29110-48-3",{"v":56,"d":"56.00"},{"v":198.2,"d":"198.20"},{"v":30,"d":"30.00"},106.18,"http://selleckchem.com/products/guanfacine-hydrochloride.html","C9H9Cl2N3O.HCl","hydrochloride","Guanfacine, Tenex, Intuniv","Cl.NC(=N)NC(=O)CC1=C(Cl)C=CC=C1Cl",2.412,1,2,3]
["S4695","D panthenol","b7","L8000-14","in 10mM DMSO","Vitamin","Metabolism","D panthenol (Dexpanthenol, D-Panthenol, Pantothenol, Ilopan, D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent.",205.25,"81-13-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/d-panthenol.html","C9H19NO4","free base","Dexpanthenol, D-Panthenol, Pantothenol, Ilopan, D-Pantothenyl alcohol","CC(C)(CO)C(O)C(=O)NCCCO",-1.266,1,4,6]
["S4696","CarbinoxaMine Maleate","c7","L8000-14","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Carbinoxamine maleate is a histamine-H1 receptor blocking agent with antihistamine and anticholinergic properties.",406.86,"3505-38-2",{"v":81,"d":"81.00"},199.09,{"v":81,"d":"81.00"},199.09,"http://selleckchem.com/products/carbinoxamine-maleate.html","C16H19ClN2O.C4H4O4","maleate","N/A","CN(C)CCOC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.OC(=O)\\C=C/C(O)=O",0.224,4,0,8]
["S4697","Saxagliptin hydrate","d7","L8000-14","in 10mM DMSO","DPP","Proteases","Saxagliptin H2O (BMS-477118, Onglyza) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.",333.43,"945667-22-1",{"v":66,"d":"66.00"},197.94,{"v":1,"d":"1.00"},{"v":3,"d":"3.00"},"http://selleckchem.com/products/saxagliptin-hydrate.html","C18H25N3O2.H2O","hydrate","BMS-477118 hydrate, Onglyza hydrate, BMS 477118 hydrate, BMS477118 hydrate","O.NC(C(=O)N1C(CC2CC12)C#N)[C]34CC5[CH2]C(C[C](O)(C5)C3)C4",0.068,1,1,2]
["S4701","2-Deoxy-D-glucose (2-DG)","e7","L8000-14","in 10mM DMSO","Apoptosis related,Carbohydrate Metabolism,HSV","Metabolism","2-Deoxy-D-glucose (2-DG, 2-deoxyglucose, NSC 15193, 2-Deoxy-D-arabino-hexose, D-Arabino-2-deoxyhexose), an analog of glucose, is a glycolytic inhibitor with antiviral activity. 2-Deoxy-D-glucose induces apoptosis and inhibits Herpes Simplex Virus type-1 (HSV-1) receptor expression.",164.16,"154-17-6",{"v":32,"d":"32.00"},194.93,{"v":32,"d":"32.00"},194.93,"http://selleckchem.com/products/2-deoxy-d-glucose.html","C6H12O5","free base","2-deoxyglucose, NSC 15193, 2-Deoxy-D-arabino-hexose, D-Arabino-2-deoxyhexose","OCC1OC(O)CC(O)C1O",-1.748,1,3,1]
["S4706","Eugenol","f7","L8000-14","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Eugenol (4-Allyl-2-methoxyphenol, 4-Allylguaiacol, Eugenic acid, Allylguaiacol) is a naturally occuring scent chemical found in clove oil and other plants. The physiologic effect of eugenol is by means of increased Histamine Release, and cell-mediated Immunity.",{"v":164.2,"d":"164.20"},"97-53-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/eugenol.html","C10H12O2","Free Base","4-Allyl-2-methoxyphenol, 4-Allylguaiacol, Eugenic acid, Allylguaiacol","COC1=C(O)C=CC(=C1)CC=C",2.579,1,1,3]
["S4707","Oleic Acid","g7","L8000-14","in 10mM DMSO","ATPase","Transmembrane Transporters","Oleic acid (Oleate, 9-Octadecenoic Acid, Elaidoic acid) is a fatty acid that occurs naturally in various animal and vegetable fats and oils. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent.  Oleic acid is an abundant monounsaturated fatty acid. Oleic acid is a Na+/K+ ATPase activator.",282.46,"112-80-1","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/oleic-acid.html","C18H34O2","Free Base","Oleate, 9-Octadecenoic Acid, Elaidoic acid","CCCCCCCC\\C=C/CCCCCCCC(O)=O",{"v":6.86,"d":"6.860"},1,0,15]
["S4709","Latanoprost","h7","L8000-14","in 10mM DMSO","GPR,Immunology & Inflammation related,RAR/RXR","Immunology & Inflammation","Latanoprost (Xalatan, PhXA41) is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. Latanoprost increases uveoscleral outflow and thereby reduces intraocular pressure.",432.59,"130209-82-4","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/latanoprost.html","C26H40O5","Free Base","Xalatan, PhXA41, PHXA-41","CC(C)OC(=O)CCC\\C=C/CC1C(O)CC(O)C1CCC(O)CCC2=CC=CC=C2",4.365,2,3,14]
["S4711","Esculetin","a8","L8000-14","in 10mM DMSO","Lipoxygenase","Metabolism","Esculetin (Cichorigenin, Aesculetin) is a coumarin derivative found in various natural plant products with various biological and pharmaceutical properties including anti-edema, anti-inflammatory and anti-tumour effects. It inhibits lipoxygenases (LOs).",178.14,"305-01-1",{"v":35,"d":"35.00"},196.47,"<1","N/A","http://selleckchem.com/products/esculetin.html","C9H6O4","free base","Cichorigenin, Aesculetin","OC1=CC2=C(C=CC(=O)O2)C=C1O",1.415,2,2,0]
["S4714","(-)-Menthol","b8","L8000-14","in 10mM DMSO","TRP Channel","Transmembrane Transporters","(-)-Menthol is a levo isomer of menthol and used as a cooling agent that strongly activates TRPM8.",156.27,"2216-51-5",{"v":31,"d":"31.00"},198.37,{"v":16,"d":"16.00"},102.39,"http://selleckchem.com/products/-menthol.html","C10H20O","free base","L-Menthol, Levomenthol, Menthomenthol, Menthacamphor","CC(C)C1CCC(C)CC1O",2.779,0,1,1]
["S4717","Isatin","c8","L8000-14","in 10mM DMSO","MAO","Metabolism","Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor with an IC50 of 15 μM and more active against MAO-B than MAO-A.",147.13,"91-56-5",{"v":29,"d":"29.00"},{"v":197.1,"d":"197.10"},"<1","N/A","http://selleckchem.com/products/isatin.html","C8H5NO2","free base","2,3-Indolinedione","O=C1NC2=C(C=CC=C2)C1=O",{"v":0.67,"d":"0.670"},2,1,0]
["S4718","Acetylcholine iodide","d8","L8000-14","in 10mM DMSO","AChR","Neuronal Signaling","Acetylcholine iodide (Acetylcolina) is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.",273.11,"2260-50-6",{"v":54,"d":"54.00"},197.72,{"v":54,"d":"54.00"},197.72,"http://selleckchem.com/products/acetylcholine-iodide.html","C7H16NO2.I","iodide salt","Acetylcolina","[I-].CC(=O)OCC[N+](C)(C)C",-4.308,2,0,4]
["S4722","(+)-Catechin","e8","L8000-14","in 10mM DMSO","Antioxidant","Immunology & Inflammation","(+)-Catechin (Cianidanol, Catechinic acid, Catechuic acid) is an antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.,",290.27,"154-23-4",{"v":58,"d":"58.00"},199.81,{"v":58,"d":"58.00"},199.81,"http://selleckchem.com/products/catechin.html","C15H14O6","free base","Cianidanol, Catechinic acid, Catechuic acid, Catechin","OC1CC2=C(OC1C3=CC(=C(O)C=C3)O)C=C(O)C=C2O",2.021,1,5,1]
["S4723","(-)Epicatechin","f8","L8000-14","in 10mM DMSO","Antioxidant","Immunology & Inflammation","(−)Epicatechin (L-Epicatechin, (-)-Epicatechol) is a flavonoid present in cocoa, green tea and red wine. It is a strong antioxidant, has insulin mimic action and improves heart health.",290.27,"490-46-0",{"v":58,"d":"58.00"},199.81,"<1","N/A","http://selleckchem.com/products/-epicatechin.html","C15H14O6","free base","L-Epicatechin, (-)-Epicatechol","OC1CC2=C(OC1C3=CC(=C(O)C=C3)O)C=C(O)C=C2O",2.021,1,5,1]
["S4725","Benzenesulfonamide","g8","L8000-14","in 10mM DMSO","Carbonic Anhydrase","Metabolism","Benzenesulfonamide (Benzenesulphonamide, Benzosulfonamide, Phenyl sulfonamide, Benzene sulfonamide) is an inhibitor of carbonic anhydrases.",157.19,"98-10-2",{"v":31,"d":"31.00"},197.21,"<1","N/A","http://selleckchem.com/products/benzenesulfonamide.html","C6H7NO2S","free base","Benzenesulphonamide, Benzosulfonamide, Phenyl sulfonamide, Benzene sulfonamide","N[S](=O)(=O)C1=CC=CC=C1",0.535,2,1,1]
["S4727","Cinnarizine","h8","L8000-14","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Cinnarizine (Stugeron, Dimitronal, Stutgin, Cinarizine) is a medication derivative of piperazine, and characterized as an antihistamine and a calcium channel blocker.",368.51,"298-57-7",{"v":73,"d":"73.00"},{"v":198.1,"d":"198.10"},"<1","N/A","http://selleckchem.com/products/cinnarizine.html","C26H28N2","free base","Stugeron, Dimitronal, Stutgin, Cinarizine","C1CN(CCN1C\\C=C\\C2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=CC=C4",5.524,0,0,6]
["S4731","Perphenazine","a9","L8000-14","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Perphenazine (Perphenazin, Trilafon, Etaperazine) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.",403.97,"58-39-9",{"v":74,"d":"74.00"},183.18,"<1","N/A","http://selleckchem.com/products/perphenazine.html","C21H26ClN3OS","free base","Perphenazin, Trilafon, Etaperazine","OCCN1CCN(CCCN2C3=CC=CC=C3SC4=C2C=C(Cl)C=C4)CC1",4.157,0,1,6]
["S4735","Salvianolic acid B","b9","L8000-14","in 10mM DMSO","Sirtuin","Epigenetics","Salvianolic acid B (Sal B, Lithospermate B, Lithospermic acid B), an antioxidant and free radical scavenging compound, is the most abundant bioactive compound extracted from the root of Salvia miltiorrhiza Bunge.",718.61,"121521-90-2",{"v":100,"d":"100.00"},139.16,{"v":100,"d":"100.00"},139.16,"http://selleckchem.com/products/salvianolic-acid-b.html","C36H30O16","free base","Sal B, Lithospermate B, Lithospermic acid B","OC(=O)C(CC1=CC(=C(O)C=C1)O)OC(=O)/C=C/C2=CC=C(O)C3=C2C(C(O3)C4=CC=C(O)C(=C4)O)C(=O)OC(CC5=CC=C(O)C(=C5)O)C(O)=O",4.718,7,7,14]
["S4736","Trapidil","c9","L8000-14","in 10mM DMSO","PDGFR","Protein Tyrosine Kinase","Trapidil (Rocornal, Trapymin, Avantrin, Trapymine) is a PDGF antagonist that can inhibit the proliferation of the PDGF-producing glioma cells.",205.26,"15421-84-8",{"v":41,"d":"41.00"},199.75,{"v":41,"d":"41.00"},199.75,"http://selleckchem.com/products/trapidil.html","C10H15N5","free base","Rocornal, Trapymin, Avantrin, Trapymine","CCN(CC)C1=CC(=NC2=NC=N[N]12)C",1.922,3,0,3]
["S4737","Psoralen","d9","L8000-14","in 10mM DMSO","ADC Cytotoxin,DNA/RNA Synthesis","DNA Damage/DNA Repair","Psoralen (Psoralene, Ficusin, Furocoumarin) is a naturally occurring furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.",186.16,"66-97-7",{"v":37,"d":"37.00"},198.75,"<1","N/A","http://selleckchem.com/products/psoralen.html","C11H6O3","free base","Psoralene, Ficusin, Furocoumarin","O=C1OC2=C(C=C1)C=C3C=COC3=C2",2.203,3,0,0]
["S4744","Anethole trithione","e9","L8000-14","in 10mM DMSO","Others","Others","Anethole trithione is a drug used in the treatment of dry mouth.",240.36,"532-11-6",{"v":48,"d":"48.00"},{"v":199.7,"d":"199.70"},"<1","N/A","http://www.selleck.cn/products/anethole-trithione.html","C10H8OS3","Free Base","N/A","COC1=CC=C(C=C1)C2=CC(=S)SS2",3.635,1,0,2]
["S4748","Ondansetron Hydrochloride Dihydrate","f9","L8000-14","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Ondansetron is a highly specific and selective serotonin 5-HT3 receptor antagonist (Ki=6.16 nM), with low affinity for dopamine receptors.",365.85,"103639-04-9",{"v":73,"d":"73.00"},199.54,{"v":73,"d":"73.00"},199.54,"http://selleckchem.com/products/ondansetron-hcl.html","C18H19N3O.HCl.2H2O","hydrochloride","N/A","O.O.Cl.C[N]1C2=C(C(=O)C(CC2)C[N]3C=CN=C3C)C4=C1C=CC=C4",2.602,2,0,2]
["S4749","Citalopram HBr","g9","L8000-14","in 10mM DMSO","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Citalopram HBr (Nitalapram HBr, Prepram HBr, Bonitrile HBr, Lu 10-171 HBr), an antidepressant, is an orally administered selective serotonin reuptake inhibitor (SSRI) with IC50 of 1.8 nM.",{"v":405.3,"d":"405.30"},"59729-32-7",{"v":81,"d":"81.00"},199.85,{"v":81,"d":"81.00"},199.85,"http://selleckchem.com/products/citalopram-hbr.html","C20H21FN2O.HBr","hydrobromide","Nitalapram HBr, Prepram HBr, Bonitrile HBr, Lu 10-171 HBr","Br.CN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C3=CC=C(F)C=C3",4.212,1,0,5]
["S4750","Sulfacetamide sodium salt hydrate","h9","L8000-14","in 10mM DMSO","Antibiotics,Autophagy,Bacterial","Autophagy","Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase(DHPS) with IC50 of 9.5 μM. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid.",254.24,"6209-17-2",{"v":50,"d":"50.00"},196.66,{"v":50,"d":"50.00"},196.66,"http://selleckchem.com/products/sulfacetamide-sodium-salt-hydrate.html","C8H9N2O3S.H2O.Na","sodium salt hyd","N/A","O.CC(=O)N([Na])[S](=O)(=O)C1=CC=C(N)C=C1",-0.326,3,1,2]
["S4751","Cisapride hydrate","a10","L8000-14","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Cisapride (Propulsid, Alimix, Propulsin, Enteropride, Kinestase) acts directly as a selective serotonin 5-HT4 receptor agonist with IC50 of 0.483 μM. And It also acts indirectly as a parasympathomimetic.",483.96,"260779-88-2",{"v":96,"d":"96.00"},198.36,"<1","N/A","https://www.selleckchem.com/products/cisapride-hydrate.html","C23H29ClFN3O4.H2O","hydrate","Propulsid, Alimix, Propulsin, Enteropride, Kinestase","O.COC1CN(CCCOC2=CC=C(F)C=C2)CCC1NC(=O)C3=CC(=C(N)C=C3OC)Cl",2.578,4,2,9]
["S4753","Ganoderic acid A","b10","L8000-14","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Ganoderic acid A (GAA), a representative active triterpenoid from Ganoderma lucidum, has been reported to exhibit antinociceptive, antioxidative, cytotoxic, hepatoprotective and anticancer activities.",516.67,"81907-62-2",{"v":100,"d":"100.00"},193.55,"<1","N/A","http://selleckchem.com/products/ganoderic-acid-a.html","C30H44O7","free base","N/A","CC(CC(=O)CC(C)C(O)=O)C1CC(O)C2(C)C3=C(C(=O)CC12C)C4(C)CCC(=O)C(C)(C)C4CC3O",2.775,4,2,6]
["S4754","Betulin","c10","L8000-14","in 10mM DMSO","Fatty Acid Synthase","Metabolism","Betulin (BE, betulinol, betuline, betulinic alcohol), also known as betulinol, betuline, or betulinic alcohol, is a pentacyclic lupane-type triterpenoid naturally distributed in many plants and displays a broad spectrum of biological and pharmacological properties such as anticancer and chemopreventive activity. Betulin (Trochol), is a sterol regulatory element-binding protein (SREBP) inhibitor with an IC50 of 14.5 μM in K562 cell line.",442.72,"473-98-3",{"v":22,"d":"22.00"},49.69,"<1","N/A","http://selleckchem.com/products/betulin.html","C30H50O2","free base","betulinol, betuline, betulinic alcohol","CC(=C)C1CCC2(CO)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC34C)C12",6.312,0,2,2]
["S4759","p-Coumaric Acid","e10","L8000-14","in 10mM DMSO","Anti-infection","Microbiology","p-Coumaric acid (4-Hydroxycinnamic acid, P-Hydroxycinnamic acid, 4-Coumaric acid, Trans-p-Coumaric acid, para-Coumaric Acid) is a hydroxy derivative of cinnamic acid found in a variety of edible plants and is reported to have antioxidant, anti-inflammatory, and antimicrobial activity.",164.16,"501-98-4",{"v":32,"d":"32.00"},194.93,"<1","N/A","http://selleckchem.com/products/p-coumaric-acid.html","C9H8O3","free base","4-Hydroxycinnamic acid, P-Hydroxycinnamic acid, 4-Coumaric acid, Trans-p-Coumaric acid, para-Coumaric Acid","OC(=O)\\C=C\\C1=CC=C(O)C=C1",1.685,1,1,2]
["S4769","L-5-Hydroxytryptophan","f10","L8000-14","in 10mM DMSO","Others","Others","5-Hydroxytryptophan (5-HTP, L-oxitriptan), also known as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin.",220.22,"4350-09-8",{"v":16,"d":"16.00"},72.65,"N/A","N/A","http://selleckchem.com/products/l-5-hydroxytryptophan.html","C11H12N2O3","free base","L-oxitriptan","NC(CC1=C[NH]C2=CC=C(O)C=C12)C(O)=O",-1.554,1,3,3]
["S4772","alpha-Asarone","g10","L8000-14","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Alpha (α)-asarone (trans-Asarone) is one of the main pharmacologically active compounds present in Acorus calamus Linn (Acoraceae), Acorus tatarinowii Schott (Acoraceae), and Acorus gramineus Solander. It has anticonvulsant, neuroprotective, anxiolytic and nootropic effects.",208.25,"2883-98-9",{"v":41,"d":"41.00"},196.88,"N/A","N/A","http://selleckchem.com/products/alpha-asarone.html","C12H16O3","free base","trans-Asarone","COC1=CC(=C(\\C=C\\C)C=C1OC)OC",2.734,3,0,4]
["S4779","Menadiol Diacetate","a11","L8000-14","in 10mM DMSO","Vitamin","Microbiology","Menadiol Diacetate (Vitamin K4, Acetomenaphthone, Kapilin) is a synthetic hydrophilic menadione compound, which is clinically used as hemostasis medicine. It induces caspase-3-related apoptosis pathway via mitochondrial dysfunction and DNA fragmentation.",258.27,"573-20-6",{"v":51,"d":"51.00"},197.47,"N/A","N/A","http://selleckchem.com/products/menadiol-diacetate.html","C15H14O4","free base","Vitamin K4, Acetomenaphthone, Kapilin","CC(=O)OC1=C2C=CC=CC2=C(OC(C)=O)C(=C1)C",2.759,4,0,4]
["S4783","Benzyl isothiocyanate","b11","L8000-14","in 10mM DMSO","Antibiotics","Microbiology","Benzyl isothiocyanate (BITC, Benzoylthiocarbimide, Isothiocyanic Acid Benzoyl Ester) is an isothiocyanate originally found in cruciferous vegetables that exhibits immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiogenic, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities.",149.21,"622-78-6",{"v":29,"d":"29.00"},194.36,"N/A","N/A","http://selleckchem.com/products/benzyl-isothiocyanate.html","C8H7NS","free base","Benzoylthiocarbimide, Isothiocyanic Acid Benzoyl Ester","S=C=NCC1=CC=CC=C1",{"v":0,"d":"0.000"},0,0,0]
["S4797","Nicergoline","e11","L8000-14","in 10mM DMSO","Adrenergic Receptor","Endocrinology & Hormones","Nicergoline is an ergot derivative used to treat senile dementia and other disorders with vascular origins. It has a selective alpha-1A adrenergic receptor blocking property and also other additional mechanisms of actions.",484.39,"27848-84-6",{"v":22,"d":"22.00"},45.42,"N/A","N/A","http://selleckchem.com/products/nicergoline.html","C24H26BrN3O3","free base","N/A","COC12CC(COC(=O)C3=CN=CC(=C3)Br)CN(C)C1CC4=C[N](C)C5=CC=CC2=C45",{"v":0,"d":"0.000"},0,0,0]
["S4817","Atenolol","g11","L8000-14","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Atenolol (Tenormin, Normiten, Blokium) is a selective β1 receptor antagonist with log Kd values of −6.66±0.05, −5.99±0.14, −4.11±0.07 for binding to the human β1-, β2- and β3-adrenoceptors.",266.34,"29122-68-7",{"v":53,"d":"53.00"},198.99,{"v":35,"d":"35.00"},131.41,"http://selleckchem.com/products/atenolol.html","C14H22N2O3","free base","Tenormin, Normiten, Blokium","CC(C)NCC(O)COC1=CC=C(CC(N)=O)C=C1",0.669,2,3,8]
["S4832","Tolmetin","h11","L8000-14","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Tolmetin (Tolectin) is a nonsteroidal anti-inflammatory drug of the heterocyclic acetic acid derivative class and also exhibits analgesic and antipyretic activity.",257.28,"26171-23-3",{"v":51,"d":"51.00"},198.23,"N/A","N/A","http://selleckchem.com/products/tolmetin.html","C15H15NO3","free base","Tolectin","C[N]1C(=CC=C1C(=O)C2=CC=C(C)C=C2)CC(O)=O",3.267,2,0,4]
["S4833","Cefoxitin sodium","a2","L8000-15","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Cefoxitin Sodium is the sodium salt form of cefoxitin, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.",449.43,"33564-30-6",{"v":89,"d":"89.00"},198.03,{"v":89,"d":"89.00"},198.03,"http://selleckchem.com/products/cefoxitin-sodium.html","C16H16N3O7S2.Na","sodium salt","N/A","[Na+].COC1(NC(=O)CC2=CC=CS2)C3SCC(=C(N3C1=O)C([O-])=O)COC(N)=O",-1.151,5,2,8]
["S4834","Propantheline bromide","b2","L8000-15","in 10mM DMSO","AChR","Neuronal Signaling","Propantheline bromide (Pro-Banthine, Neometantyl, Neopepulsan) is a muscarinic antagonist used to treat gastrointestinal conditions associated with intestinal spasm and to decrease secretions during anesthesia.",448.39,"50-34-0",{"v":89,"d":"89.00"},198.49,"N/A","N/A","http://selleckchem.com/products/propantheline-bromide.html","C23H30NO3.Br","bromide","Pro-Banthine, Neometantyl, Neopepulsan","[Br-].CC(C)[N+](C)(CCOC(=O)C1C2=C(OC3=CC=CC=C13)C=CC=C2)C(C)C",0.763,3,0,7]
["S4835","Aceclofenac","c2","L8000-15","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Aceclofenac (Preservex, Airtal) is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties.",354.18,"89796-99-6",{"v":70,"d":"70.00"},197.64,"N/A","N/A","http://selleckchem.com/products/aceclofenac.html","C16H13Cl2NO4","free base","Preservex, Airtal","OC(=O)COC(=O)CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1",{"v":4.08,"d":"4.080"},3,1,7]
["S4836","Nilutamide","d2","L8000-15","in 10mM DMSO","Androgen Receptor","Endocrinology & Hormones","Nilutamide (RU23908) is a nonsteroidal antiandrogen (NSAA) with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors). It is used in the treatment of prostate cancer.",317.22,"63612-50-0",{"v":63,"d":"63.00"},{"v":198.6,"d":"198.60"},"<1","N/A","http://selleckchem.com/products/nilutamide.html","C12H10F3N3O4","Nonsteroidal antiandrogens","RU23908","CC1(C)NC(=O)N(C2=CC=C(C(=C2)C(F)(F)F)[N+]([O-])=O)C1=O",2.254,2,1,3]
["S4837","Ibudilast","e2","L8000-15","in 10mM DMSO","PDE","Metabolism","Ibudilast (KC-404, AV411, MN166) is a relatively non-selective phosphodiesterase inhibitor with anti-inflammatory and neuroprotective activities.",230.31,"50847-11-5",{"v":46,"d":"46.00"},199.73,{"v":30,"d":"30.00"},130.26,"http://selleckchem.com/products/Ibudilast.html","C14H18N2O","free base","KC-404, AV411, MN166","CC(C)C(=O)C1=C2C=CC=C[N]2N=C1C(C)C",3.339,2,0,3]
["S4838","Acotiamide hydrochloride","f2","L8000-15","in 10mM DMSO","AChR","Neuronal Signaling","Acotiamide Hydrochloride (YM-443, Z-338) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. It is a new orally active selective acetylcholinesterase inhibitor.",541.06,"773092-05-0",{"v":100,"d":"100.00"},184.82,{"v":5,"d":"5.00"},9.24,"http://selleckchem.com/products/acotiamide-hydrochloride.html","C21H30N4O5S.HCl.3H2O","hydrochloride trihydrate","YM-443 HCl, Z-338 HCl","O.O.O.Cl.COC1=CC(=C(C=C1OC)C(=O)NC2=NC(=CS2)C(=O)NCCN(C(C)C)C(C)C)O",2.325,5,3,10]
["S4849","Levocetirizine Dihydrochloride","g2","L8000-15","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Levocetirizine (Xyzal, (-)-Cetirizine) is the active R-enantiomer of cetirizine and represents a new second-generation histamine H1 antagonist.",461.81,"130018-87-0",{"v":92,"d":"92.00"},199.22,{"v":92,"d":"92.00"},199.22,"http://selleckchem.com/products/levocetirizine-dihydrochloride.html","C21H25ClN2O3.2HCl","dihydrochloride","Xyzal Dihydrochloride, (-)-Cetirizine Dihydrochloride","Cl.Cl.OC(=O)COCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3",1.217,2,0,8]
["S4852","Gadopentetate Dimeglumine","h2","L8000-15","in 10mM DMSO","Others","Others","Gadopentetate Dimeglumine (Gadopentetic acid dimeglumine, Gd-DTPA, Meglumine gadopentetate), a complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid, is an extracellular intravenous contrast agent used in magnetic resonance imaging.",{"v":938,"d":"938.00"},"86050-77-3",{"v":100,"d":"100.00"},106.61,"N/A","N/A","http://selleckchem.com/products/gadopentetate-dimeglumine.html","C14H18GdN3O10.2C7H17NO5.2H","dimeglumine salt","Gadopentetic acid dimeglumine, Gd-DTPA, Meglumine gadopentetate","CNCC(O)C(O)C(O)C(O)CO.CNCC(O)C(O)C(O)C(O)CO.OC(=O)CN1CCN2CCN(CC(O)=O)CC(=O)O[Gd](OC(=O)C2)OC(=O)C1",-13.058,8,12,16]
["S4856","Iproniazid","a3","L8000-15","in 10mM DMSO","MAO","Metabolism","Iproniazid (Marsilid, Iprazid) is a non-selective, irreversible monoamine oxidase (MAO) inhibitor (MAOI) that is used as an antidepressive agent.",179.22,"54-92-2",{"v":35,"d":"35.00"},195.29,{"v":35,"d":"35.00"},195.29,"http://selleckchem.com/products/Iproniazid.html","C9H13N3O","free base","Marsilid, Iprazid","CC(C)NNC(=O)C1=CC=NC=C1",0.121,2,2,3]
["S4862","Squalene","b3","L8000-15","in 10mM DMSO","Fungal","Microbiology","Squalene (Spinacene, Supraene, trans-Squalene), a naturally occurring substance found in plants, animals and humans, is a component of some adjuvants that is added to vaccines to enhance the immune response.",410.72,"111-02-4","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/squalene.html","C30H50","free base","Spinacene, Supraene, trans-Squalene","CC(C)=CCC\\C(C)=C\\CC\\C(C)=C\\CC\\C=C(C)\\CC\\C=C(C)\\CCC=C(C)C",11.331,0,0,15]
["S4867","Propacetamol hydrochloride","c3","L8000-15","in 10mM DMSO","Others","Others","Propacetamol hydrochloride (PRO) is a water-soluble prodrug of paracetamol (PA) which can be parenterally administered as analgesic for the treatment of postoperative pain, acute trauma, and gastric and/or intestinal disorders.",300.78,"66532-86-3",{"v":60,"d":"60.00"},199.48,{"v":60,"d":"60.00"},199.48,"http://selleckchem.com/products/propacetamol-hydrochloride.html","C14H20N2O3.HCl","hydrochloride","N/A","Cl.CCN(CC)CC(=O)OC1=CC=C(NC(C)=O)C=C1",1.803,3,1,7]
["S4878","Neticonazole Hydrochloride","d3","L8000-15","in 10mM DMSO","Fungal","Microbiology","Neticonazole is an imidazole antifungal for the treatment of fungal skin infections.",{"v":338.9,"d":"338.90"},"130773-02-3",{"v":67,"d":"67.00"},{"v":197.7,"d":"197.70"},"N/A","N/A","http://selleckchem.com/products/neticonazole-hydrochloride.html","C17H22N2OS.HCl","hydrochloride","N/A","Cl.CCCCCOC1=CC=CC=C1C(=C\\SC)/[N]2C=CN=C2",3.838,2,0,8]
["S4885","Taurolidine","e3","L8000-15","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Taurolidine (Taurolin, Tauroline, Tauroflex) is a synthetic broad-spectrum antibiotic with antibacterial, anticoagulant and potential antiangiogenic activities.",284.36,"19388-87-5",{"v":56,"d":"56.00"},196.93,"N/A","N/A","http://selleckchem.com/products/taurolidine.html","C7H16N4O4S2","free base","Taurolin, Tauroline, Tauroflex","O=[S]1(=O)CCN(CN1)CN2CC[S](=O)(=O)NC2",-1.991,4,2,2]
["S4896","Elagolix Sodium","g3","L8000-15","in 10mM DMSO","GNRH Receptor","Endocrinology & Hormones","Elagolix Soidum (NBI-56418, ABT-620) is a potent, selective, orally active, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with Kd value of 54 pM. Concentration at 10 μM shows no significant activity on ion channels, enzymes, and transporters (inhibition <50%).",653.57,"832720-36-2",{"v":100,"d":"100.00"},153.01,{"v":100,"d":"100.00"},153.01,"http://selleckchem.com/products/elagolix-sodium.html","C32H29F5N3O5.Na","sodium","NBI-56418, ABT-620","[Na+].COC1=C(F)C(=CC=C1)C2=C(C)N(CC3=C(F)C=CC=C3C(F)(F)F)C(=O)N(CC(NCCCC([O-])=O)C4=CC=CC=C4)C2=O",4.104,3,1,13]
["S4932","Proxyphylline","h3","L8000-15","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","Proxyphylline (Monophylline, Spasmolysin) is a derivative of theophylline which is used as a bronchodilator and for its cardiovascular properties. It selectively antagonizes A1 adenosine receptors (Ki = 82 nM for bovine brain) versus A2 adenosine receptors (Ki = 850 µM for platelets).",238.24,"603-00-9",{"v":47,"d":"47.00"},197.28,"N/A","N/A","http://selleckchem.com/products/proxyphylline.html","C10H14N4O3","free base","Monophylline, Spasmolysin","CC(O)C[N]1C=NC2=C1C(=O)N(C)C(=O)N2C",-0.262,3,1,2]
["S4940","Maltol","a4","L8000-15","in 10mM DMSO","Antioxidant","PI3K/Akt/mTOR","Maltol (Larixinic acid, Palatone, Veltol) is a naturally occurring organic compound that is flavour enhancer and flavouring agent.",126.11,"118-71-8",{"v":25,"d":"25.00"},198.24,"N/A","N/A","http://selleckchem.com/products/maltol.html","C6H6O3","Pyrone ","Larixinic acid, Palatone, Veltol","CC1=C(O)C(=O)C=CO1",-0.222,2,1,0]
["S4941","Farnesol","b4","L8000-15","in 10mM DMSO","Antibiotics","Microbiology","Farnesol is a natural sesquiterpene alcohol that is potent in treating antimetabolic disorders, anti-inflammation, showing antioxidant, anticancer, and antibiotic effects.",222.37,"4602-84-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/farnesol.html","C15H26O","free base","N/A","CC(C)=CCCC(/C)=C/CCC(/C)=C/CO",{"v":4.76,"d":"4.760"},0,1,7]
["S4952","Fumaric acid","c4","L8000-15","in 10mM DMSO","Others","Others","Fumaric acid (Fumarate, 2-Butenedioic acid, Trans-Butenedioic acid) is an intermediate in the citric acid cycle used by cells to produce energy in the form of adenosine triphosphate (ATP) from food; also a product of the urea cycle.",116.07,"110-17-8",{"v":23,"d":"23.00"},198.16,"N/A","N/A","http://selleckchem.com/products/fumaric-acid.html","C4H4O4","free base","2-Butenedioic acid, Trans-Butenedioic acid, Allomaleic acid, Boletic acid, Donitic acid, Lichenic acid, Fumarate","OC(=O)\\C=C\\C(O)=O",0.038,2,0,2]
["S4953","Usnic acid","d4","L8000-15","in 10mM DMSO","Akt,ERK","PI3K/Akt/mTOR","Usnic acid (Usniacin) is a furandione found uniquely in lichen that is used widely in cosmetics, deodorants, toothpaste and medicinal creams as well as some herbal products. It exhibits antiviral, antiprotozoal, antiproliferative, anti-inflammatory and analgesic activity. Usnic acid inhibits breast tumor angiogenesis and growth by suppressing VEGFR2-mediated AKT and ERK1/2 signaling pathways.",344.32,"125-46-2",{"v":4,"d":"4.00"},11.62,"N/A","N/A","http://selleckchem.com/products/usnic-acid.html","C18H16O7","free base","Usniacin","CC(=O)C1C(=O)C=C2OC3=C(C(=C(C)C(=C3C(C)=O)O)O)C2(C)C1=O",1.084,5,2,2]
["S4957","Linalool","e4","L8000-15","in 10mM DMSO","NMDAR","Neuronal Signaling","Linalool (Phantol), a monoterpene compound commonly found as major component of essential oils of several aromatic species, is a competitive antagonist of NMDA receptors.",154.25,"78-70-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/linalool.html","C10H18O","free base","Phantol","CC(C)=CCCC(C)(O)C=C",2.735,0,0,4]
["S4958","Glycocholic acid","f4","L8000-15","in 10mM DMSO","Others","Others","Glycocholic acid (Cholylglycine, Glycocholate) is a natural secondary bile acid involved in the emulsification of fats.",465.62,"475-31-0",{"v":93,"d":"93.00"},199.73,"N/A","N/A","http://selleckchem.com/products/glycocholic-acid.html","C26H43NO6","free base","Cholylglycine, Glycocholate","CC(CCC(=O)NCC(O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CC(O)C12C",1.972,2,4,6]
["S4975","Fimasartan","g4","L8000-15","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Fimasartan (Kanarb) is a non-peptide angiotensin II receptor antagonist (ARB) with noncompetitive, insurmountable binding with the AT1 receptor. It is used for the treatment of hypertension and heart failure.",501.65,"247257-48-3",{"v":100,"d":"100.00"},199.34,"N/A","N/A","http://selleckchem.com/products/fimasartan.html","C27H31N7OS","free base","Kanarb","CCCCC1=NC(=C(CC(=S)N(C)C)C(=O)N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=N[NH]4)C",4.515,5,1,10]
["S4976","Sulfalene (SMPZ)","h4","L8000-15","in 10mM DMSO","Others","Others","Sulfalene (SMPZ, Butadiene sulfone, 3-Sulfolene) is a cyclic organic chemical used as a versatile synthetic intermediate.",{"v":280.3,"d":"280.30"},"152-47-6",{"v":56,"d":"56.00"},199.79,"<1","N/A","http://selleckchem.com/products/sulfalene-smpz.html","C11H12N4O3S","free base","Butadiene sulfone, 3-Sulfolene","COC1=C(N[S](=O)(=O)C2=CC=C(N)C=C2)N=CC=N1",0.331,5,2,4]
["S4977","Efonidipine","a5","L8000-15","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Efonidipine (NZ-105) is an L- and T-type calcium channel blocker leading to vasodilation and decreased automaticity of the heart. It also suppresses aldosterone secretion from the adrenal.",631.66,"111011-63-3",{"v":100,"d":"100.00"},158.31,"N/A","N/A","http://selleckchem.com/products/efonidipine.html","C34H38N3O7P","free base","NZ-105","CC1=C(C(C2=CC(=CC=C2)[N+]([O-])=O)C(=C(C)N1)[P]3(=O)OCC(C)(C)CO3)C(=O)OCCN(CC4=CC=CC=C4)C5=CC=CC=C5",4.956,4,1,11]
["S4980","Anamorelin","b5","L8000-15","in 10mM DMSO","GHSR","GPCR & G Protein","Anamorelin (ONO-7643, RC-1291, ST-1291) is an orally active, high-affinity, selective agonist of the ghrelin receptor with an EC50 value of 0.74 nM in the HEK293/GRLN  FLIPR assay.",{"v":546.7,"d":"546.70"},"249921-19-5",{"v":100,"d":"100.00"},182.92,"<1","N/A","http://selleckchem.com/products/anamorelin.html","C31H42N6O3","free base","ONO-7643, RC-1291, ST-1291","CN(C)N(C)C(=O)C1(CCCN(C1)C(=O)C(CC2=C[NH]C3=C2C=CC=C3)NC(=O)C(C)(C)N)CC4=CC=CC=C4",2.447,3,3,9]
["S4988","Tiamulin fumarate","c5","L8000-15","in 10mM DMSO","Ribosomal Peptidyl Transferase","Microbiology","Tiamulin fumarate is a semisynthetic pleuromutilin antibiotic that binds to the ribosomal peptidyl transferase centre and inhibits protein synthesis.",609.81,"55297-96-6",{"v":100,"d":"100.00"},163.99,{"v":100,"d":"100.00"},163.99,"http://selleckchem.com/products/tiamulin-fumarate.html","C28H47NO4S.C4H4O4","fumarate","N/A","CCN(CC)CCSCC(=O)OC1CC(C)(C=C)C(O)C(C)C23CCC(C)C1(C)C2C(=O)CC3.OC(=O)\\C=C\\C(O)=O",1.366,5,1,12]
["S5001","Tofacitinib (CP-690550) Citrate","d5","L8000-15","in 10mM DMSO","Anti-infection,JAK","JAK/STAT","Tofacitinib citrate (CP-690550, Tasocitinib) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively. Tofacitinib citrate has anti-infection activity.",504.49,"540737-29-9",{"v":100,"d":"100.00"},198.22,"<1","N/A","http://selleckchem.com/products/CP-690550.html","C16H20N6O.C6H8O7","Citrate","Tasocitinib Citrate,CP-690550","CC1CCN(CC1N(C)C2=C3C=C[NH]C3=NC=N2)C(=O)CC#N.OC(=O)CC(O)(CC(O)=O)C(O)=O",0.193,6,1,8]
["S5002","Fingolimod (FTY720) HCl","e5","L8000-15","in 10mM DMSO","S1P Receptor","GPCR & G Protein","Fingolimod (FTY720, Fingolimod Hydrochloride) HCl is a S1P antagonist with IC50 of 0.033 nM in K562, and NK cells.",{"v":343.9,"d":"343.90"},"162359-56-0",{"v":69,"d":"69.00"},200.64,{"v":69,"d":"69.00"},200.64,"http://selleckchem.com/products/FTY720.html","C19H33NO2.HCl","Hydrochloride","Fingolimod Hydrochloride,FTY720","Cl.CCCCCCCCC1=CC=C(CCC(N)(CO)CO)C=C1",{"v":4.58,"d":"4.580"},0,3,12]
["S5003","Tacrolimus (FK506)","f5","L8000-15","in 10mM DMSO","Autophagy,FKBP,phosphatase","PI3K/Akt/mTOR","Tacrolimus (FK506, FR900506, Fujimycin, Prograf) is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex. Tacrolimus also inhibits the phosphatase activity of calcineurin. Tacrolimus induces vascular endothelial autophagy.",804.02,"104987-11-3",{"v":94,"d":"94.00"},116.91,"<1","N/A","http://selleckchem.com/products/FK-506-(Tacrolimus).html","C44H69NO12","free base","FK506, FR900506, Fujimycin, Prograf","COC1CC(CCC1O)\\C=C(C)\\C2OC(=O)C3CCCCN3C(=O)C(=O)C4(O)OC(C(CC(C)C/C(=C/C(CC=C)C(=O)CC(O)C2C)C)OC)C(CC4C)OC",4.832,9,2,7]
["S5006","Teprenone","g5","L8000-15","in 10mM DMSO","HSP (HSP90)","Cytoskeletal Signaling","Teprenone, an acylic polyisoprenoid, that is known as tetraprenylacetone or geranylgeranylacetone, is an anti-ulcer drug, clinically used for gastritis.  Teprenone(Geranylgeranylacetone) is an inducer of heat shock proteins (HSPs) expression.",330.55,"6809-52-5",{"v":66,"d":"66.00"},199.67,"N/A","N/A","http://selleckchem.com/products/teprenone.html","C23H38O","Isoprenoids","Geranylgeranylacetone, Tetraprenylacetone","CC(C)=CCC/C(C)=C/CC\\C(C)=C\\CC\\C(C)=C\\CCC(C)=O",7.413,1,0,12]
["S5007","Delamanid","h5","L8000-15","in 10mM DMSO","Bacterial","Microbiology","Delamanid (OPC-67683) is a new anti-tuberculosis drug with an excellent intracellular bactericidal activity and a high accumulation rate.",534.48,"681492-22-8",{"v":100,"d":"100.00"},{"v":187.1,"d":"187.10"},"<1","N/A","http://selleckchem.com/products/delamanid.html","C25H25F3N4O6","free base","OPC-67683","CC1(COC2=CC=C(C=C2)N3CCC(CC3)OC4=CC=C(OC(F)(F)F)C=C4)C[N]5C=C(N=C5O1)[N+]([O-])=O",6.452,5,0,9]
["S5009","Brivudine","a6","L8000-15","in 10mM DMSO","CMV","Microbiology","Brivudine (BVDU) is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. It is incorporated into the viral DNA and blocks the action of DNA polymerases, thus inhibiting viral replication.",333.14,"69304-47-8",{"v":66,"d":"66.00"},198.11,"N/A","N/A","http://selleckchem.com/products/brivudine.html","C11H13BrN2O5","free base","BVDU","OCC1OC(CC1O)N2C=C(\\C=C\\Br)C(=O)NC2=O",-1.034,3,3,3]
["S5012","Octenidine Dihydrochloride","b6","L8000-15","in 10mM DMSO","Bacterial","Microbiology","Octenidine, a cationic surfactant, is active against gram-positive and gram-negative bacteria.",623.83,"70775-75-6",{"v":60,"d":"60.00"},96.18,"N/A","N/A","http://selleckchem.com/products/octenidine-ihydrochloride.html","C36H62N4.2HCl","Dihydrochloride","N/A","Cl.Cl.CCCCCCCCN=C1C=CN(CCCCCCCCCCN2C=CC(C=C2)=NCCCCCCCC)C=C1",{"v":10.56,"d":"10.560"},2,0,25]
["S5014","Crisaborole (AN2728)","c6","L8000-15","in 10mM DMSO","PDE","Metabolism","Crisaborole (AN2728) is a small-molecule, boron-based, selective PDE4 inhibitor and has broad-spectrum anti-inflammatory activity.",251.05,"906673-24-3",{"v":50,"d":"50.00"},199.16,"N/A","N/A","http://selleckchem.com/products/crisaborole-an2728.html","C14H10BNO3","free base","N/A","OB1OCC2=CC(=CC=C12)OC3=CC=C(C=C3)C#N",3.538,2,0,2]
["S5016","Isoprinosine","d6","L8000-15","in 10mM DMSO","Antiviral,Immunology & Inflammation related","Microbiology","Isoprinosine (Inosine pranobex, Immunovir, Groprinosin, Delimmun) is an immunopharmacologic agent with antiviral activities.",1115.23,"36703-88-5",{"v":100,"d":"100.00"},89.67,{"v":100,"d":"100.00"},89.67,"http://selleckchem.com/products/isoprinosine.html","C10H12N4O5.3C9H9NO3.3C5H13NO","salt","Inosine pranobex, Immunovir, Groprinosin, Delimmun","CC(O)CN(C)C.CC(O)CN(C)C.CC(O)CN(C)C.CC(=O)NC1=CC=C(C=C1)C(O)=O.CC(=O)NC2=CC=C(C=C2)C(O)=O.CC(=O)NC3=CC=C(C=C3)C(O)=O.OCC4OC(C(O)C4O)[N]5C=NC6=C5N=CNC6=O",-9.137,10,10,14]
["S5020","Tilorone dihydrochloride","e6","L8000-15","in 10mM DMSO","Antiviral,IFN","Immunology & Inflammation","Tilorone dihydrochloride is a broad-spectrum, orally active antiviral agent that activates interferon production. It has antitumor, anti-inflammatory properties.",483.47,"27591-69-1",{"v":43,"d":"43.00"},88.94,{"v":96,"d":"96.00"},198.56,"http://selleckchem.com/products/tilorone-dihydrochloride.html","C25H34N2O3.2HCl","dihydrochloride","N/A","Cl.Cl.CCN(CC)CCOC1=CC2=C(C=C1)C3=C(C=C(OCCN(CC)CC)C=C3)C2=O",5.326,3,0,12]
["S5023","Nadolol","f6","L8000-15","in 10mM DMSO","Adrenergic Receptor","Endocrinology & Hormones","Nadolol (Corgard, Solgol, Anabet, SQ11725) is a non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities.",{"v":309.4,"d":"309.40"},"42200-33-9",{"v":61,"d":"61.00"},197.16,"N/A","N/A","http://selleckchem.com/products/nadolol.html","C17H27NO4","free base","Corgard, Solgol, Anabet, SQ11725","CC(C)(C)NCC(O)COC1=CC=CC2=C1CC(O)C(O)C2",1.146,1,4,6]
["S5027","Mebeverine Hydrochloride","g6","L8000-15","in 10mM DMSO","Others","Others","Mebeverine (Duspatalin, Duspatal, Colofac), a 3-phenylethylamine derivative of methoxybenzamine, acts as a musculotropic antispasmodic agent.",466.01,"2753-45-9",{"v":93,"d":"93.00"},199.57,"N/A","N/A","http://selleckchem.com/products/mebeverine-hydrochlo.html","C25H35NO5.HCl","hydrochloride","Duspatalin Hydrochloride, Duspatal Hydrochloride, Colofac Hydrochloride","Cl.CCN(CCCCOC(=O)C1=CC=C(OC)C(=C1)OC)C(C)CC2=CC=C(OC)C=C2",{"v":5.43,"d":"5.430"},5,0,14]
["S5029","Etofylline","h6","L8000-15","in 10mM DMSO","Others","Others","Etofylline (Aethophyllinum, Cordalin, Oxyphylline) is a N-7 substituted theophylline derivative used as a bronchodilator.",224.22,"519-37-9",{"v":44,"d":"44.00"},196.24,{"v":44,"d":"44.00"},196.24,"http://selleckchem.com/products/etofylline.html","C9H12N4O3","Methylxanthines","Aethophyllinum, Cordalin, Oxyphylline","CN1C(=O)N(C)C2=C([N](CCO)C=N2)C1=O",{"v":-0.64,"d":"-0.640"},3,1,2]
["S5032","Mephenesin","a7","L8000-15","in 10mM DMSO","NMDAR","Neuronal Signaling","Mephenesin (Decontractyl, Cresoxydiol, Memphenesin, Mephedan) is centrally acting muscle relaxant, a topical analgesic and may be an NMDA receptor antagonist.",182.22,"59-47-2",{"v":36,"d":"36.00"},197.56,{"v":30,"d":"30.00"},164.64,"http://selleckchem.com/products/mephenesin.html","C10H14O3","free base","Decontractyl, Cresoxydiol, Memphenesin, Mephedan","CC1=C(OCC(O)CO)C=CC=C1",1.249,1,2,4]
["S5033","Terconazole","b7","L8000-15","in 10mM DMSO","Fungal","Microbiology","Terconazole (Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol,R42470) is a new, broad-spectrum, triazole antifungal agent which is primarily used to treat vaginal fungal infections.",532.46,"67915-31-5",{"v":49,"d":"49.00"},92.03,"<1","N/A","http://selleckchem.com/products/terconazole.html","C26H31Cl2N5O3","free base","Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol,R42470","CC(C)N1CCN(CC1)C2=CC=C(OCC3COC(C[N]4C=NC=N4)(O3)C5=CC=C(Cl)C=C5Cl)C=C2",4.949,5,0,8]
["S5040","Tiamulin","c7","L8000-15","in 10mM DMSO","Ribosomal Peptidyl Transferase","Microbiology","Tiamulin is a semisynthetic pleuromutilin antibiotic that binds to the ribosomal peptidyl transferase centre and inhibits protein synthesis. Tiamulin has sustained antibacterial activity against specified bacterial species and rapidly growing and fastidious animal pathogens.",493.74,"55297-95-5",{"v":25,"d":"25.00"},50.63,{"v":11,"d":"11.00"},22.28,"http://selleckchem.com/products/tiamulin.html","C28H47NO4S","free base","N/A","CCN(CC)CCSCC(=O)OC1CC(C)(C=C)C(O)C(C)C23CCC(C)C1(C)C2C(=O)CC3",4.361,3,1,10]
["S5049","Thiocolchicoside","d7","L8000-15","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Thiocolchicoside (Thiocolchicine 2-glucoside analog, Coltramyl) is a natural occuring glycoside originated from the flower seeds of superba gloriosa with anti-inflammatory and analgesic properties as well as pronounced convulsant activity. It is also an antagonist of GABAA receptor.",563.62,"602-41-5",{"v":100,"d":"100.00"},177.42,{"v":100,"d":"100.00"},177.42,"http://selleckchem.com/products/thiocolchicoside.html","C27H33NO10S","Phenolic glycosides","Thiocolchicine 2-glucoside analog, Coltramyl","COC1=C(OC)C2=C(CCC(NC(C)=O)C3=CC(=O)C(=CC=C23)SC)C=C1OC4OC(CO)C(O)C(O)C4O",0.446,6,5,7]
["S5052","Granisetron","e7","L8000-15","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Granisetron (Sancuso, Kevatril, Granisetronum, Sustol) is a serotonin receptor (5HT-3 selective) antagonist that is used as an antiemetic and antinauseant for cancer chemotherapy.",312.41,"109889-09-0",{"v":11,"d":"11.00"},35.21,"N/A","N/A","http://selleckchem.com/products/granisetron.html","C18H24N4O","Serotonin 5-HT3 receptor","Sancuso, Kevatril, Granisetronum, Sustol","CN1C2CCCC1CC(C2)NC(=O)C3=N[N](C)C4=C3C=CC=C4",2.401,2,1,2]
["S5058","Revaprazan Hydrochloride","f7","L8000-15","in 10mM DMSO","ATPase,Proton Pump","Transmembrane Transporters","Revaprazan Hydrochloride (YH1885) is a new reversible proton pump inhibitor with long-lasting acid-suppressive effects. Revaprazan Hydrochloride reversibly inhibits H(+)/K(+)-ATPase via binding to the K+-binding site of the pump.",{"v":398.9,"d":"398.90"},"178307-42-1",{"v":16,"d":"16.00"},40.11,"N/A","N/A","http://selleckchem.com/products/revaprazan-hydrochloride.html","C22H23FN4.HCl","HCl","YH1885","Cl.CC1N(CCC2=C1C=CC=C2)C3=NC(=NC(=C3C)C)NC4=CC=C(F)C=C4",6.215,2,1,3]
["S5059","Pixantrone Maleate","g7","L8000-15","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Pixantrone (BBR-2778) is a novel aza-anthracenedione compound with antitumor activity. It is a weak topoisomerase II inhibitor and forms stable DNA adducts through alkylation with specificity for DNA hypermethylated sites.",557.51,"144675-97-8",{"v":100,"d":"100.00"},179.37,{"v":100,"d":"100.00"},179.37,"http://selleckchem.com/products/pixantrone-maleate.html","C17H19N5O2.2C4H4O4","dimaleate","BBR-2778","NCCNC1=CC=C(NCCN)C2=C1C(=O)C3=C(C=NC=C3)C2=O.OC(=O)\\C=C/C(O)=O.OC(=O)\\C=C/C(O)=O",-5.263,7,4,10]
["S5060","Metadoxine","h7","L8000-15","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Metadoxine (Metadoxil, Metasin, pyridoxine-pyrrolidone carboxylat), also known as pyridoxine-pyrrolidone carboxylate, is a drug used to treat chronic and acute alcohol intoxication.  Metadoxine is a novel 5-HT2B receptor antagonist with a possible therapeutic role in treating ADHD.",298.29,"74536-44-0",{"v":59,"d":"59.00"},197.79,"N/A","N/A","http://selleckchem.com/products/metadoxine.html","C8H11NO3.C5H7NO3","salt","Metadoxil, Metasin, pyridoxine-pyrrolidone carboxylat","CC1=C(O)C(=C(CO)C=N1)CO.OC(=O)C2CCC(=O)N2",-1.243,3,4,3]
["S5062","Daclatasvir Dihydrochloride","a8","L8000-15","in 10mM DMSO","HCV Protease","Microbiology","Daclatasvir is an orally available antiviral agent that inhibits the NS5A region of the hepatitis C virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection.",{"v":811.8,"d":"811.80"},"1009119-65-6",{"v":100,"d":"100.00"},123.18,{"v":100,"d":"100.00"},123.18,"https://www.selleckchem.com/products/daclatasvir-dihydrochloride.html","C40H50N8O6.2HCl","dihydrochloride","N/A","Cl.Cl.COC(=O)NC(C(C)C)C(=O)N1CCCC1C2=NC=C([NH]2)C3=CC=C(C=C3)C4=CC=C(C=C4)C5=CN=C([NH]5)C6CCCN6C(=O)C(NC(=O)OC)C(C)C",5.812,8,4,13]
["S5067","Losartan","b8","L8000-15","in 10mM DMSO","Angiotensin Receptor","GPCR & G Protein","Losartan(DuP-753) is a selective, orally administered, nonpeptide blocker of angiotensin II type 1 (AT1) receptor used to treat high blood pressure, diabetic kidney disease, heart failure, and left ventricular enlargement.",422.91,"114798-26-4",{"v":84,"d":"84.00"},198.62,{"v":-1,"d":"-1.00"},-2.36,"https://www.selleckchem.com/products/losartan.html","C22H23ClN6O","free base","DuP-753","CCCCC1=NC(=C(CO)[N]1CC2=CC=C(C=C2)C3=C(C=CC=C3)C4=NN=N[NH]4)Cl",4.241,4,2,8]
["S5069","Dabrafenib Mesylate","c8","L8000-15","in 10mM DMSO","Raf","MAPK","Dabrafenib Mesylate (GSK2118436) is the mesylate salt form of dabrafenib, an orally bioavailable inhibitor of B-raf (BRAF) protein with IC50s of 0.8 nM, 3.2 nM and 5 nM for B-Raf (V600E), B-Raf (WT) and C-Raf, respectively.",615.67,"1195768-06-9",{"v":100,"d":"100.00"},162.42,"<1","N/A","http://selleckchem.com/products/dabrafenib-mesylate.html","C23H20F3N5O2S2.CH4O3S","mesylate","GSK2118436 Mesylate","CC(C)(C)C1=NC(=C(S1)C2=CC=NC(=N2)N)C3=C(F)C(=CC=C3)N[S](=O)(=O)C4=C(F)C=CC=C4F.C[S](O)(=O)=O",4.963,5,2,6]
["S5074","Argatroban Monohydrate","d8","L8000-15","in 10mM DMSO","Thrombin","Proteases","Argatroban (Argatroban hydrate, Argipidine,MCI-9038 Monohydrate) is a direct, selective thrombin inhibitor with anticoagulant effects.",526.65,"141396-28-3",{"v":100,"d":"100.00"},189.88,"<1","N/A","http://selleckchem.com/products/argatroban-monohydrate.html","C23H36N6O5S.H2O","Thrombin inhibitors","Argatroban hydrate, Argipidine,MCI-9038 Monohydrate","O.CC1CCN(C(C1)C(O)=O)C(=O)C(CCCNC(N)=N)N[S](=O)(=O)C2=CC=CC3=C2NCC(C)C3",1.059,4,4,10]
["S5077","Regorafenib (BAY-734506) Monohydrate","e8","L8000-15","in 10mM DMSO","c-Kit,c-RET,PDGFR,Raf,VEGFR","Protein Tyrosine Kinase","Regorafenib (BAY-734506, Fluoro-sorafenib, Resihance, Stivarga, regorafaenib monohydrate) Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, Kit (c-Kit), RET (c-RET), RAF-1, B-RAF and B-RAF(V600E) respectively.",500.83,"1019206-88-2",{"v":100,"d":"100.00"},199.67,"N/A","N/A","http://selleckchem.com/products/regorafenib-monohydrate.html","C21H15ClF4N4O3.H2O","monohydrate","Fluoro-sorafenib, Resihance, Stivarga, regorafaenib monohydrate","O.CNC(=O)C1=NC=CC(=C1)OC2=CC=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C(=C2)F",4.174,4,3,6]
["S5078","Osimertinib mesylate","f8","L8000-15","in 10mM DMSO","EGFR","Protein Tyrosine Kinase","Osimertinib mesylate (AZD9291) is the mesylate form of osimertinib, which is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug.",595.71,"1421373-66-1",{"v":9,"d":"9.00"},15.11,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/osimertinib-mesylate.html","C29H37N7O5S","mesylate","AZD9291 mesylate","COC1=C(NC2=NC=CC(=N2)C3=C[N](C)C4=C3C=CC=C4)C=C(NC(=O)C=C)C(=C1)N(C)CCN(C)C.C[S](O)(=O)=O",4.257,4,2,10]
["S5082","Vitamin K2","g8","L8000-15","in 10mM DMSO","Vitamin","Metabolism","Vitamin K2 (Menaquinone) is an important fat-soluble vitamin that plays critical roles in protecting heart and brain, and building strong bones. It also plays an important role in cancer protection.",444.65,"863-61-6",{"v":88,"d":"88.00"},197.91,"N/A","N/A","http://selleckchem.com/products/vitamin-k2.html","C31H40O2","free base","Menaquinone","CC(C)=CCC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC1=C(C)C(=O)C2=C(C=CC=C2)C1=O",{"v":9.5,"d":"9.500"},2,0,11]
["S5083","Lentinan","h8","L8000-15","in 10mM DMSO","Fungal,Immunology & Inflammation related","Immunology & Inflammation","Lentinan (A823605, Bromoduline), isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.","N/A","37339-90-5",{"v":100,"d":"100.00"},{"v":10,"d":"10.00"},"N/A","N/A","http://selleckchem.com/products/lentinan.html","C42H70O35R2","Polysaccharides","A823605, Bromoduline","O(C1C(O)C(CO)OC(OCC2OC(OC3C(O)C(CO)OC(OC4C(O)C(COC5OC(CO)C(O)C(O)C5O)OC(OC6C(O)C(OC(CO)C6O)[*])C4O)C3O)C(O)C(OC7OC(CO)C(O)C(O)C7O)C2O)C1O)[*]",-10.494,14,21,20]
["S5091","Geranyl acetate","a9","L8000-15","in 10mM DMSO","Others","Apoptosis","Geranyl acetate (Geraniol acetate, Geranyl ethanoate) is a natural organic compound that is used primarily as a component of perfumes for creams and soaps and as a flavoring ingredient. Geranyl acetate exhibits anti-cancer effects by inducing cell apoptosis.",196.29,"105-87-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/geranyl-acetate.html","C12H20O2","free base","Geraniol acetate, Geranyl ethanoate","CC(=O)OC/C=C(C)/CCC=C(C)C",3.313,2,0,6]
["S5113","Propyl gallate","b9","L8000-15","in 10mM DMSO","PPAR","Metabolism","Propyl gallate (Gallic acid propyl esterZ, n-Propyl gallate) is an antioxidant used in foods especially animal fats and vegetable oils, also in a wide variety of cosmetics and beauty care products.",{"v":212.2,"d":"212.20"},"121-79-9",{"v":42,"d":"42.00"},197.93,"N/A","N/A","http://selleckchem.com/products/propyl-gallate.html","C10H12O5","free base","Gallic acid propyl esterZ, n-Propyl gallate","CCCOC(=O)C1=CC(=C(O)C(=C1)O)O",{"v":0,"d":"0.000"},0,0,0]
["S5130","Taurocholic acid sodium salt hydrate","d9","L8000-15","in 10mM DMSO","Others","Others","Taurocholic acid (Sodium taurocholate hydrate), a bile salt formed in the liver, is the product of conjugation of cholic acid with taurine that is involved in the emulsification of lipids. Its sodium salt is the chief ingredient of the bile of carnivorous animals.","537.68 (anhydrous basis)","345909-26-4",{"v":100,"d":"100.00"},185.98,"N/A","N/A","http://selleckchem.com/products/taurocholic-acid-sodium-salt-hydrate.html","C26H45NO7S.xH2O.Na","sodium salt, hydrate","Sodium taurocholate hydrate","[Na+].CC(CCC(=O)NCC[S]([O-])(=O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CC(O)C12C",{"v":0,"d":"0.000"},0,0,0]
["S5138","Citral","e9","L8000-15","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Citral (Geranialdehyde) is an α,β-unsaturated aldehyde present in the oils of several plants. It is an aroma compound used in perfumery for its citrus effect and is also used as a flavor and for fortifying lemon oil.",152.23,"5392-40-5","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/citral.html","C10H16O","free base","Geranialdehyde","CC(C)=CCCC(/C)=C/C=O",{"v":0,"d":"0.000"},0,0,0]
["S5141","Pyrithioxin","f9","L8000-15","in 10mM DMSO","Others","Others","Pyrithioxin (Bonifen, Encefabol, Pyritinol, Vitamin B6 disulfide) is a neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity.",368.47,"1098-97-1",{"v":60,"d":"60.00"},162.84,"N/A","N/A","http://selleckchem.com/products/pyrithioxin.html","C16H20N2O4S2","free base","Bonifen, Encefabol, Pyritinol, Vitamin B6 disulfide","CC1=NC=C(CSSCC2=CN=C(C)C(=C2CO)O)C(=C1O)CO",{"v":0,"d":"0.000"},0,0,0]
["S5145","Protoporphyrin IX","g9","L8000-15","in 10mM DMSO","Others","Others","Protoporphyrin IX (PPIX) is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway.",562.66,"553-12-8",{"v":100,"d":"100.00"},177.73,"N/A","N/A","http://selleckchem.com/products/protoporphyrin-ix.html","C34H34N4O4","free base","PPIX","CC1=C2[NH]C(=C1CCC(O)=O)C=C3N=C(C=C4N=C(C=C5[NH]C(=C2)C(=C5C)C=C)C(=C4C)C=C)C(=C3CCC(O)=O)C",{"v":0,"d":"0.000"},0,0,0]
["S5159","Doxycycline","h9","L8000-15","in 10mM DMSO","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Bacterial,MMP","Microbiology","Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum) is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. Doxycycline is also a nonspecific matrix metalloproteinase (MMP) inhibitor.",444.43,"564-25-0",{"v":88,"d":"88.00"},198.01,"N/A","N/A","http://selleckchem.com/products/doxycycline.html","C22H24N2O8","free base","Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum","CC1C2C(O)C3C(N(C)C)C(=C(C(N)=O)C(=O)C3(O)C(=C2C(=O)C4=C1C=CC=C4O)O)O",{"v":0,"d":"0.000"},0,0,0]
["S5163","7-Methoxycoumarin","a10","L8000-15","in 10mM DMSO","Others","Others","7-Methoxycoumarin (Herniarine), also known as Herniarin, is a methoxy derivative of coumarin and substrate for dealkylase. It has been used in the synthesis of anti-first-pass effect compounds and detergents.",176.17,"531-59-9",{"v":35,"d":"35.00"},198.67,"N/A","N/A","http://selleckchem.com/products/7-methoxycoumarin.html","C10H8O3","free base","Herniarin, Herniarine","COC1=CC2=C(C=CC(=O)O2)C=C1",{"v":0,"d":"0.000"},0,0,0]
["S5177","Naproxen","b10","L8000-15","in 10mM DMSO","COX","Immunology & Inflammation","Naproxen is an anti-inflammatory agent with analgesic and antipyretic properties. It is a nonselective inhibitor of COX-1 and COX-2.",230.26,"22204-53-1",{"v":46,"d":"46.00"},199.77,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/naproxen.html","C14H14O3","Free Base","N/A","COC1=CC2=CC=C(C=C2C=C1)C(C)C(O)=O",2.849,2,0,3]
["S5200","Diaveridine","c10","L8000-15","in 10mM DMSO","DHFR","Metabolism","Diaveridine (AI3-23935, CCRIS-3784) is coccidiostat with anti-parasitic activity and also a dihydrofolate reductase (DHFR) inhibitor preventing folic acid synthesis in species of Pneumocystis.",260.29,"5355-16-8",{"v":25,"d":"25.00"},96.05,"N/A","N/A","http://selleckchem.com/products/diaveridine.html","C13H16N4O2","free base","AI3-23935, CCRIS-3784","COC1=C(OC)C=C(CC2=CN=C(N)N=C2N)C=C1",1.559,4,2,4]
["S5205","Nilotinib hydrochloride","d10","L8000-15","in 10mM DMSO","Bcr-Abl","Angiogenesis","Nilotinib hydrochloride (AMN-107) is the hydrochloride salt form of nilotinib, an orally bioavailable Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity.",565.98,"923288-95-3",{"v":100,"d":"100.00"},176.69,{"v":-1,"d":"-1.00"},-1.77,"http://selleckchem.com/products/nilotinib-hydrochloride.html","C28H22F3N7O.HCl","hydrochloride","AMN-107 HCl","Cl.CC1=C[N](C=N1)C2=CC(=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C)C(=C3)NC4=NC=CC(=N4)C5=CC=CN=C5",5.466,5,2,7]
["S5209","Enoxacin Sesquihydrate","e10","L8000-15","in 10mM DMSO","Bacterial","Microbiology","Enoxacin sesquihydrate (Enoxacin hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.",347.34,"84294-96-2",{"v":4,"d":"4.00"},11.52,"N/A","N/A","http://selleckchem.com/products/enoxacin-sesquihydrate.html","C15H17FN4O3.3/2H2O","sesquihydrate","Enoxacin hydrate","CCN1C=C(C(O)=O)C(=O)C2=C1N=C(N3CCNCC3)C(=C2)F",-0.749,3,1,3]
["S5210","Sulfamethazine Sodium Salt","f10","L8000-15","in 10mM DMSO","Anti-infection","Microbiology","Sulfamethazine (Sulfadimethyldiazine) is a sulfanilamide anti-infective agent used in the lifestock industry.",300.31,"1981-58-4",{"v":60,"d":"60.00"},199.79,"N/A","N/A","http://selleckchem.com/products/sulfamethazine-sodium-salt.html","C12H13N4O2S.Na","sodium salt","Sulfadimethyldiazine Sodium Salt","CC1=CC(=NC(=N1)N([Na])[S](=O)(=O)C2=CC=C(N)C=C2)C",0.982,4,1,3]
["S5211","4-Aminosalicylic acid","g10","L8000-15","in 10mM DMSO","Bacterial","Microbiology","4-Aminosalicylic acid (Para-aminosalicylic acid, Aminosalicylic acid, 4-aminosalicylate) is an antitubercular agent with bacteriostatic activity against Mycobacterium tuberculosis.",153.14,"65-49-6",{"v":10,"d":"10.00"},{"v":65.3,"d":"65.30"},"N/A","N/A","http://selleckchem.com/products/4-aminosalicylic-acid.html","C7H7NO3","free base","Para-aminosalicylic acid, Aminosalicylic acid, 4-aminosalicylate","NC1=CC(=C(C=C1)C(O)=O)O",0.471,1,2,1]
["S5233","Fenretinide (NSC 374551)","h10","L8000-15","in 10mM DMSO","Retinoid Receptor","Metabolism","Fenretinide (4-hydroxy(phenyl)retinamide, 4-HPR, MK-4016) is a synthetic derivative of retinoic acid that has a broad-spectrum of cytotoxic activity against primary tumor cells, cell lines, and/or xenografts of various cancers (including neuroblastoma). Fenretinide (4-hydroxy(phenyl)retinamide; 4-HPR) is a synthetic derivative of retinoic acid, fenretinide can bind to retinoic acid receptor (RAR) and retinoid X receptor (RXR) at concentrations necessary to induce cell death.",391.55,"65646-68-6",{"v":78,"d":"78.00"},199.21,"<1","N/A","http://selleckchem.com/products/fenretinide.html","C26H33NO2","free base","4-hydroxy(phenyl)retinamide, 4-HPR, MK-4016","CC1=C(\\C=C\\C(C)=C\\C=C\\C(C)=C\\C(=O)NC2=CC=C(O)C=C2)C(C)(C)CCC1",6.463,1,2,6]
["S5234","Nintedanib Ethanesulfonate Salt","a11","L8000-15","in 10mM DMSO","FGFR,PDGFR,VEGFR","Protein Tyrosine Kinase","Nintedanib (Intedanib, BIBF 1120) is a small molecule tyrosine-kinase inhibitor with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β, respectively.",649.76,"656247-18-6",{"v":100,"d":"100.00"},{"v":153.9,"d":"153.90"},{"v":100,"d":"100.00"},{"v":153.9,"d":"153.90"},"http://selleckchem.com/products/nintedanib-ethanesulfonate-salt.html","C31H33N5O4.C2H6O3S","ethanesulfonate","Intedanib, BIBF 1120","CC[S](O)(=O)=O.COC(=O)C1=CC2=C(C=C1)C(/C(=O)N2)=C(NC3=CC=C(C=C3)N(C)C(=O)CN4CCN(C)CC4)\\C5=CC=CC=C5",{"v":2.9,"d":"2.900"},4,2,9]
["S5240","Lenvatinib (E7080) Mesylate","b11","L8000-15","in 10mM DMSO","c-Kit,c-RET,FGFR,PDGFR,VEGFR","Protein Tyrosine Kinase","Lenvatinib Mesylate (E7080) is a synthetic, orally available tyrosine kinase inhibitor that inhibits vascular endothelial growth factor receptor (VEGFR1-3), fibroblast growth factor receptor (FGFR1-4), platelet-derived growth factor receptor α (PDGFRα), stem cell factor receptor (Kit (c-Kit)), and rearranged during transfection (RET (c-RET)). Lenvatinib Mesylate has potential antineoplastic activity.",522.96,"857890-39-2",{"v":39,"d":"39.00"},74.58,{"v":-1,"d":"-1.00"},-1.91,"http://selleckchem.com/products/lenvatinib-mesylate.html","C21H19ClN4O4.CH4O3S","Mesylate","E7080 mesylate","COC1=C(C=C2C(=CC=NC2=C1)OC3=CC(=C(NC(=O)NC4CC4)C=C3)Cl)C(N)=O.C[S](O)(=O)=O",2.418,5,3,6]
["S5241","Lapatinib ditosylate monohydrate","c11","L8000-15","in 10mM DMSO","HER2","Protein Tyrosine Kinase","Lapatinib ditosylate monohydrate (Lapatinib ditoluenesulfonate monohydrate, Lapatinib tosilate, Lapatinib tosilate hydrate)is a dual tyrosine kinase inhibitor which interrupts the HER2/neu and epidermal growth factor receptor (EGFR) pathways, used for treatment of solid tumours such as breast and lung cancer.",943.48,"388082-78-8",{"v":100,"d":"100.00"},105.99,{"v":-1,"d":"-1.00"},-1.06,"https://www.selleckchem.com/products/lapatinib-ditosylate-monohydrate.html","C43H44ClFN4O11S3","ditosylate monohydrate","Lapatinib ditoluenesulfonate monohydrate, Lapatinib tosilate, Lapatinib tosilate hydrate","O.CC1=CC=C(C=C1)[S](O)(=O)=O.CC2=CC=C(C=C2)[S](O)(=O)=O.C[S](=O)(=O)CCNCC3=CC=C(O3)C4=CC5=C(C=C4)N=CN=C5NC6=CC(=C(OCC7=CC(=CC=C7)F)C=C6)Cl",9.132,6,2,13]
["S5243","Ruxolitinib Phosphate","d11","L8000-15","in 10mM DMSO","Apoptosis related,Autophagy,JAK,Mitophagy","JAK/STAT","Ruxolitinib Phosphate (INCB018424, INC424) is the phosphate salt form of Ruxolitinib. Ruxolitinib is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis.",404.36,"1092939-17-7",{"v":80,"d":"80.00"},197.84,{"v":29,"d":"29.00"},71.72,"http://selleckchem.com/products/ruxolitinib-phosphate.html","C17H18N6.H3O4P","phosphate","INCB018424, INC424","O[P](O)(O)=O.N#CCC(C1CCCC1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4",2.412,3,1,4]
["S5247","Selamectin","e11","L8000-15","in 10mM DMSO","Parasite","Microbiology","Selamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a  wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas.",769.96,"220119-17-5",{"v":100,"d":"100.00"},129.88,"N/A","N/A","https://www.selleckchem.com/products/selamectin.html","C43H63NO11","free base","UK-124114","COC1CC(OC(C)C1O)OC/2C(C)\\C=C\\C=C\\3COC4/C(=N/O)C(=CC(C(=O)OC5CC(C\\C=C2C)OC6(CCC(C)C(O6)C7CCCCC7)C5)C34O)C",5.315,9,1,4]
["S5253","Cisapride (R 51619)","f11","L8000-15","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Cisapride (R 51619, Kaudalit, Kinestase, Prepulsid, Presid, Pridesia, Propulsid) is a nonselective 5-HT4 receptor agonist with gastroprokinetic effects.",465.95,"81098-60-4",{"v":93,"d":"93.00"},199.59,"<1","N/A","http://selleckchem.com/products/cisapride.html","C23H29ClFN3O4","Benzamide ","Kaudalit, Kinestase, Prepulsid, Presid, Pridesia, Propulsid","COC1CN(CCCOC2=CC=C(F)C=C2)CCC1NC(=O)C3=C(OC)C=C(N)C(=C3)Cl",2.785,4,2,9]
["S5254","Dasatinib hydrochloride","g11","L8000-15","in 10mM DMSO","Bcr-Abl,kit,Src","Angiogenesis","Dasatinib hydrochloride (BMS-354825) is the hydrochloride salt form of dasatinib, an inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively.",524.47,"854001-07-3",{"v":100,"d":"100.00"},190.67,{"v":11,"d":"11.00"},20.97,"https://www.selleckchem.com/products/dasatinib-hydrochloride.html","C22H27Cl2N7O2S","hydrochloride","BMS-354825 HCl","Cl.CC1=NC(=CC(=N1)NC2=NC=C(S2)C(=O)NC3=C(C)C=CC=C3Cl)N4CCN(CCO)CC4",3.821,4,3,7]
["S5256","Benproperine phosphate","h11","L8000-15","in 10mM DMSO","Actin,Microtubule Associated","Cytoskeletal Signaling","Benproperine phosphate (Blascorid, Pirexyl), a cough suppressant, is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. Benproperine phosphate attenuates the actin polymerization rate of action polymerization nucleation by impairing Arp2/3 function. Benproperine phosphate suppresses cancer cell migration and tumor metastasis.",407.44,"19428-14-9",{"v":60,"d":"60.00"},147.26,{"v":81,"d":"81.00"},{"v":198.8,"d":"198.80"},"http://selleckchem.com/products/benproperine-phosphate.html","C21H27NO.H3O4P","phosphate","Blascorid, Pirexyl phosphate","CC(COC1=C(CC2=CC=CC=C2)C=CC=C1)N3CCCCC3.O[P](O)(O)=O",4.753,1,0,6]
["S5273","Canrenone","a2","L8000-16","in 10mM DMSO","Mineralocorticoid Receptor","Endocrinology & Hormones","Canrenone (Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone), a cardiovascular drug, a sort of steroid, is spironolactone's major metabolite and has been widely used as a nonselective aldosterone receptor antagonist clinically to treat heart failure, high blood pressure, edema, liver ascites, and other cardiovascular diseases.",340.46,"976-71-6",{"v":68,"d":"68.00"},199.73,"N/A","N/A","http://selleckchem.com/products/canrenone.html","C22H28O3","free base","Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone","CC12CCC(=O)C=C1C=CC3C2CCC4(C)C3CCC45CCC(=O)O5",3.519,3,0,0]
["S5278","Tedizolid (TR-700)","b2","L8000-16","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Tedizolid(TR-700) is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.",370.34,"856866-72-3",{"v":10,"d":"10.00"},{"v":27,"d":"27.00"},{"v":-1,"d":"-1.00"},{"v":-2.7,"d":"-2.70"},"https://www.selleckchem.com/products/tedizolid.html","C17H15FN6O3","Oxazolidinone","N/A","C[N]1N=NC(=N1)C2=CC=C(C=N2)C3=C(F)C=C(C=C3)N4CC(CO)OC4=O",1.784,6,1,4]
["S5279","Fendiline hydrochloride","c2","L8000-16","in 10mM DMSO","Calcium Channel,Ras","Transmembrane Transporters","Fendiline hydrochloride is the hydrochloride salt form of Fendiline, which is an L-type calcium channel blocker and also a specific inhibitor of K-Ras plasma membrane targeting with no detectable effect on the localization of H- and N-Ras.",351.91,"13636-18-5",{"v":70,"d":"70.00"},198.91,"N/A","N/A","http://selleckchem.com/products/fendiline-hydrochloride.html","C23H25N.HCl","hydrochloride","N/A","Cl.CC(NCCC(C1=CC=CC=C1)C2=CC=CC=C2)C3=CC=CC=C3",5.772,0,1,7]
["S5281","Dapiprazole Hydrochloride","d2","L8000-16","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Dapiprazole Hydrochloride (Glamidolo Hydrochloride, Reversil Hydrochloride) is the hydrochloride salt form of dapiprazole, an alpha-adrenergic blocker used to reverse mydriasis after eye examination.",361.91,"72822-13-0",{"v":21,"d":"21.00"},58.03,{"v":72,"d":"72.00"},198.94,"http://selleckchem.com/products/dapiprazole-hydrochloride.html","C19H27N5.HCl","hydrochloride","Glamidolo Hydrochloride, Reversil Hydrochloride","Cl.CC1=C(C=CC=C1)N2CCN(CC2)CCC3=NN=C4CCCC[N]34",3.384,2,0,4]
["S5284","Adenosine 5'-monophosphate monohydrate","e2","L8000-16","in 10mM DMSO","AMPK","PI3K/Akt/mTOR","Adenosine 5'-monophosphate monohydrate (5'-Adenylic acid, 5'-AMP) is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK).",365.24,"18422-05-4",{"v":9,"d":"9.00"},24.64,"N/A","N/A","http://selleckchem.com/products/adenosine-5-monophosphate-monohydrate.html","C10H14N5O7P.H2O","hydrate","5'-Adenylic acid, 5'-AMP","O.NC1=NC=NC2=C1N=C[N]2C3OC(CO[P](O)(O)=O)C(O)C3O",{"v":-2.16,"d":"-2.160"},5,3,4]
["S5286","Ramatroban","f2","L8000-16","in 10mM DMSO","Prostaglandin Receptor","Metabolism","Ramatroban (BAY u 3405) is a thromboxane A2(TxA2) receptor antagonist with Ki value of 10 to 13 nM. It also antagonizes a newly identified PGD2 receptor, CRTh2 expressed on the inflammatory cells.",416.47,"116649-85-5",{"v":83,"d":"83.00"},199.29,"<1","N/A","http://selleckchem.com/products/ramatroban.html","C21H21FN2O4S","free base","BAY u 3405","OC(=O)CC[N]1C2=C(CC(CC2)N[S](=O)(=O)C3=CC=C(F)C=C3)C4=CC=CC=C14",{"v":3.51,"d":"3.510"},3,1,6]
["S5288","Estropipate","g2","L8000-16","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estropipate (Piperazine estrone sulfate, Estrone sulfate piperazine salt, Pipestrone) is a natural estrogenic substance composed of estrone sulfate and piperazine and is used mainly in menopausal hormone therapy in the treatment of menopausal symptoms.",436.56,"7280-37-7",{"v":87,"d":"87.00"},199.28,{"v":-1,"d":"-1.00"},-2.29,"https://www.selleckchem.com/products/estropipate.html","C22H32N2O5S","Estrogen","Piperazine estrone sulfate, Estrone sulfate piperazine salt, Pipestrone","CC12CCC3C(CCC4=C3C=CC(=C4)O[S](O)(=O)=O)C1CCC2=O.C5CNCCN5",2.751,2,2,2]
["S5293","Nimustine Hydrochloride","h2","L8000-16","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Nimustine Hydrochloride (Nidran) is the hydrochloride salt of nimustine, a nitrosourea with antineoplastic activity that alkylates and crosslinks DNA, thereby causing DNA fragmentation, inhibition of protein synthesis, and cell death.",309.15,"55661-38-6",{"v":61,"d":"61.00"},197.32,"N/A","N/A","http://selleckchem.com/products/nimustine-hydrochloride.html","C9H13ClN6O2.HCl","hydrochloride","Nidran hydrochloride","Cl.CC1=NC=C(CNC(=O)N(CCCl)N=O)C(=N1)N",{"v":0.47,"d":"0.470"},4,2,5]
["S5297","Vidarabine monohydrate","a3","L8000-16","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Vidarabine (Spongoadenosine, Vira-A) is a nucleoside antibiotic with antiviral acitivity that interferes with the synthesis of viral DNA. It is used to treat herpes simplex and varicella zoster viruses.",285.26,"24356-66-9",{"v":57,"d":"57.00"},199.82,"N/A","N/A","http://selleckchem.com/products/vidarabine-monohydrate.html","C10H13N5O4.H2O","hydrate","Spongoadenosine monohydrate, Vira-A monohydrate","O.NC1=NC=NC2=C1N=C[N]2C3OC(CO)C(O)C3O",-2.088,4,4,2]
["S5298","Amoxicillin trihydrate","b3","L8000-16","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Amoxicillin (Amoxil, Amoxipen, Moxaline) is a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity.",419.45,"61336-70-7",{"v":30,"d":"30.00"},71.52,"N/A","N/A","http://selleckchem.com/products/amoxicillin-trihydrate.html","C16H19N3O5S.3H2O","trihydrate","Amoxil trihydrate, Amoxipen trihydrate, Moxaline trihydrate","O.O.O.CC1(C)SC2C(NC(=O)C(N)C3=CC=C(O)C=C3)C(=O)N2C1C(O)=O",-3.161,3,3,4]
["S5301","Carglumic Acid","c3","L8000-16","in 10mM DMSO","CPSase","Metabolism","Carglumic Acid (arbamylglutamic acid, Carbamino-L-glutamic acid, Ureidoglutaric acid, N-Carbamylglutamate) is an orally active, synthetic structural analogue of N-acetylglutamate (NAG) and carbamoyl phosphate synthetase 1 (CPS 1) activator, with ammonia lowering activity.",190.15,"1188-38-1",{"v":38,"d":"38.00"},199.84,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/carglumic-acid.html","C6H10N2O5","Free Base","Carbamylglutamic acid, Carbamino-L-glutamic acid, Ureidoglutaric acid, N-Carbamylglutamate","NC(=O)NC(CCC(O)=O)C(O)=O",-1.169,3,2,5]
["S5325","Nitisinone","e3","L8000-16","in 10mM DMSO","Others","Metabolism","Nitisinone (NTBC, Nitisone, SC0735) is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase used in the treatment of hereditary tyrosinemia type 1.",329.23,"104206-65-7",{"v":65,"d":"65.00"},197.43,"<1","N/A","http://selleckchem.com/products/nitisinone.html","C14H10F3NO5","free base","NTBC, Nitisone, SC0735","[O-][N+](=O)C1=CC(=CC=C1C(=O)C2C(=O)CCCC2=O)C(F)(F)F",{"v":2.53,"d":"2.530"},3,0,4]
["S5327","Meisoindigo","f3","L8000-16","in 10mM DMSO","Others","Apoptosis","Meisoindigo (N-Methylisoindigotin, Methylisoindigotin, Dian III), a derivative of Indigo naturalis, is an active compound of a Chinese anti-leukemia medicine that has been effectively used in the treatment of chronic myelogenous leukemia (CML). In vitro cell line studies have shown that this agent might induce apoptosis and myeloid differentiation of acute myeloid leukemia (AML).",276.29,"97207-47-1",{"v":55,"d":"55.00"},199.07,"<1","N/A","http://selleckchem.com/products/meisoindigo.html","C17H12N2O2","free base","N-Methylisoindigotin, Methylisoindigotin, Dian III","CN1C(=O)/C(C2=C1C=CC=C2)=C3/C(=O)NC4=CC=CC=C34",1.851,2,1,0]
["S5341","Metroprolol succinate","g3","L8000-16","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Metroprolol Succinate (Metoprolol succinate) is the succinate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity.",652.82,"98418-47-4",{"v":100,"d":"100.00"},153.18,{"v":100,"d":"100.00"},153.18,"http://selleckchem.com/products/metroprolol-succinate.html","C34H56N2O10","succinate","Metoprolol succinate","COCCC1=CC=C(OCC(O)CNC(C)C)C=C1.COCCC2=CC=C(OCC(O)CNC(C)C)C=C2.OC(=O)CCC(O)=O",-2.255,6,4,21]
["S5345","(+/-)-nerolidol","h3","L8000-16","in 10mM DMSO","Parasite","Microbiology","(+/-)-nerolidol is a naturally occurring sesquiterpene found in the essential oils of many types of plants and flowers. It has diverse range of pharmacological and biological activities including antioxidant, anti-microbial, anti-biofilm, anti-parasitic, insecticidal, anti-ulcer, skin penetration enhancer, anti-tumor, anti-nociceptive and anti-inflammatory properties.",222.37,"7212-44-4","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/nerolidol.html","C15H26O","free base","Peruviol","CC(C)=CCC/C(C)=C/CCC(C)(O)C=C",4.561,0,0,7]
["S5353","Cefpiramide sodium","a4","L8000-16","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Cefpiramide sodium (CPMS, SM-1652,wy-44635) is an anionic β-lactam antibiotic. It exhibits antibacterial activity against gram-positive and gram-negative bacteria, in particular, to Pseudomonas aeruginosa, which can result in achronic life-threatening infection in the lungs of cystic fibrosis patients.",634.62,"74849-93-7",{"v":100,"d":"100.00"},157.57,{"v":100,"d":"100.00"},157.57,"http://selleckchem.com/products/cefpiramide-sodium.html","C25H23N8NaO7S2","Cephalosporin ","SM-1652, wy-44635","[Na+].C[N]1N=NN=C1SCC2=C(N3C(SC2)C(NC(=O)C(NC(=O)C4=C(O)C=C(C)N=C4)C5=CC=C(O)C=C5)C3=O)C([O-])=O",-1.425,7,4,9]
["S5358","Regadenoson","b4","L8000-16","in 10mM DMSO","Adenosine Receptor","GPCR & G Protein","Regadenoson (CVT-3146, Lexiscan) is a selective A2A adenosine receptor agonist with coronary vasodilating activity.",390.35,"313348-27-5",{"v":56,"d":"56.00"},143.46,"<1","N/A","http://selleckchem.com/products/regadenoson.html","C15H18N8O5","free base","CVT-3146, Lexiscan","CNC(=O)C1=C[N](N=C1)C2=NC3=C(N=C[N]3C4OC(CO)C(O)C4O)C(=N2)N",-1.925,6,5,4]
["S5365","Alogliptin","c4","L8000-16","in 10mM DMSO","DPP","Proteases","Alogliptin is a potent, selective inhibitor of the serine protease dipeptidyl peptidase IV (DPP-4) with IC50 values of 2.63 nM and exhibits greater than 10,000 fold selectivity over the closely related serine proteases DPP-8 and DPP-9.",339.39,"850649-61-5",{"v":67,"d":"67.00"},197.41,{"v":18,"d":"18.00"},53.04,"http://selleckchem.com/products/alogliptin.html","C18H21N5O2","Dipeptidyl Peptidase-4","SYR 322","CN1C(=O)C=C(N2CCCC(N)C2)N(CC3=CC=CC=C3C#N)C1=O",1.271,2,1,3]
["S5366","Fipronil","d4","L8000-16","in 10mM DMSO","Anti-infection","Microbiology","Fipronil (Fluocyanobenpyrazole, Termidor) is a recalcitrant phenylpyrazole-based pesticide used for flea/tick treatment and termite control that is distributed in urban aquatic environments via stormwater and contributes to stream toxicity.",437.15,"120068-37-3",{"v":87,"d":"87.00"},199.02,"N/A","N/A","http://selleckchem.com/products/fipronil.html","C12H4Cl2F6N4OS","free base","Fluocyanobenpyrazole, Termidor","NC1=C(C(=N[N]1C2=C(Cl)C=C(C=C2Cl)C(F)(F)F)C#N)[S](=O)C(F)(F)F",5.579,2,1,4]
["S5369","Ethoxyquin","e4","L8000-16","in 10mM DMSO","HSP (HSP90)","Cytoskeletal Signaling","Ethoxyquin (Santoquin, Santoflex, Quinol) is an antioxidant used as a food preservative.  Ethoxyquin is an antioxidant which has been used in animal feed for many years and also an inhibitor of heat shock protein 90 (Hsp90).",217.31,"91-53-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",{"v":10,"d":"10.00"},"N/A","N/A","http://selleckchem.com/products/ethoxyquin.html","C14H19NO","free base","Santoquin, Santoflex, Quinol","CCOC1=CC2=C(NC(C)(C)C=C2C)C=C1",3.221,1,1,2]
["S5371","Ajmaline","f4","L8000-16","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Ajmaline (Cardiorythmine, Tachmalin), found in the root of Rauwolfia serpentina, is a class Ia antiarrhythmic agent.",326.43,"4360-12-7",{"v":65,"d":"65.00"},199.12,{"v":-1,"d":"-1.00"},-3.06,"https://www.selleckchem.com/products/ajmaline.html","C20H26N2O2","free base","Cardiorythmine, Tachmalin","CCC1C(O)N2C3CC1C4C(O)C5(CC24)C3N(C)C6=CC=CC=C56",1.932,0,2,1]
["S5372","Methyl Aminolevulinate Hydrochloride","g4","L8000-16","in 10mM DMSO","Others","Others","Methyl Aminolevulinate (Aminolevulinic acid methyl ester Hydrochloride, Methyl 5-aminolevulinate Hydrochloride) is a prodrug that is metabolised to protoporphyrin IX used in photodynamic therapy.",181.62,"79416-27-6",{"v":36,"d":"36.00"},198.22,{"v":-1,"d":"-1.00"},-5.51,"https://www.selleckchem.com/products/methyl-aminolevulinate-hydrochloride.html","C6H12ClNO3","free base","Aminolevulinic acid methyl ester Hydrochloride, Methyl 5-aminolevulinate Hydrochloride","Cl.COC(=O)CCC(=O)CN",-0.613,3,1,5]
["S5377","Dibutyl phthalate","h4","L8000-16","in 10mM DMSO","Others","Others","Dibutyl phthalate is widely used as plasticizer in numerous kinds of products such as plastic packaging in food industries.",278.34,"84-74-2","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/dibutyl-phthalate.html","C16H22O4","free base","N/A","CCCCOC(=O)C1=C(C=CC=C1)C(=O)OCCCC",4.198,4,0,10]
["S5392","Mepivacaine","a5","L8000-16","in 10mM DMSO","Others","Others","Mepivacaine (Carbocaine) is a local anesthetic indicated for infiltration, nerve block, and epidural anesthesia.",246.35,"96-88-8",{"v":49,"d":"49.00"},198.91,{"v":-1,"d":"-1.00"},-4.06,"https://www.selleckchem.com/products/mepivacaine.html","C15H22N2O","free base","Carbocaine","CN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",2.981,1,1,2]
["S5398","Nefazodone hydrochloride","b5","L8000-16","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Nefazodone hydrochloride (BMY-13754-1) is the hydrochloride salt form of nefazodone, which is an atypical antidepressant showing antagonistic activity on serotonin reuptake.",506.47,"82752-99-6",{"v":22,"d":"22.00"},43.44,{"v":-1,"d":"-1.00"},-1.97,"https://www.selleckchem.com/products/nefazodone-hydrochloride.html","C25H33Cl2N5O2","free base","BMY-13754-1","Cl.CCC1=NN(CCCN2CCN(CC2)C3=CC(=CC=C3)Cl)C(=O)N1CCOC4=CC=CC=C4",4.797,3,0,10]
["S5399","Chlorprothixene hydrochloride","c5","L8000-16","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Chlorprothixene HCl (Minithixen hydrochloride, Truxal hydrochloride, NSC 169899, NSC 56379, NSC 78193) is the  hydrochloride salt form of chlorprothixene, a typical antipsychotic drug of the thioxanthene (tricyclic) class. It exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors.",352.32,"6469-93-8",{"v":70,"d":"70.00"},198.68,{"v":-1,"d":"-1.00"},-2.84,"https://www.selleckchem.com/products/chlorprothixene-hydrochloride.html","C18H19Cl2NS","free base","Minithixen hydrochloride, Truxal hydrochloride, NSC 169899, NSC 56379, NSC 78193","Cl.CN(C)CC\\C=C/1C2=C(SC3=C1C=C(Cl)C=C3)C=CC=C2",5.505,0,0,3]
["S5401","Tegaserod Maleate","d5","L8000-16","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Tegaserod Maleate(HTF-919) is a hydrogen maleate salt form of tegaserod, which is a 5-HT4 receptor partial agonist and binds with high affinity to 5-HT4 receptors. It has limited affinity for 5-HT1 receptors and no appreciable affinity for other 5-HT receptors, muscarinic, adrenergic, dopaminergic or opiate receptors.",417.46,"189188-57-6",{"v":83,"d":"83.00"},198.82,"<1","N/A","http://selleckchem.com/products/tegaserod-maleate.html","C16H23N5O.C4H4O4","maleate","HTF-919","CCCCCNC(=N)N/N=C/C1=C[NH]C2=C1C=C(OC)C=C2.OC(=O)\\C=C/C(O)=O",{"v":3.17,"d":"3.170"},4,3,11]
["S5407","Squalane","e5","L8000-16","in 10mM DMSO","Others","Others","Squalane (Perhydrosqualene, Dodecahydrosqualene) is a naturally occuring lipid in both plants and animals. It is usually used as an emollient and moisturizer in cosmetics manufacturing.",422.81,"111-01-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/squalane.html","C30H62","free base","Perhydrosqualene, Dodecahydrosqualene","CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C",12.831,0,0,21]
["S5416","Metyrapone","f5","L8000-16","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Metyrapone (NSC-25265, SU-4885) is an inhibitor of the enzyme steroid 11-beta-monooxygenase (CYP11B1) that inhibits adrenal steroid synthesis.",226.27,"54-36-4",{"v":46,"d":"46.00"},203.29,{"v":-1,"d":"-1.00"},-4.42,"https://www.selleckchem.com/products/metyrapone.html","C14H14N2O","free base","NSC-25265, SU-4885","CC(C)(C1=CC=CN=C1)C(=O)C2=CC=CN=C2",1.847,3,0,3]
["S5418","Parecoxib Sodium","g5","L8000-16","in 10mM DMSO","COX","Immunology & Inflammation","Parecoxib Sodium (SC-69124) is a water-soluble, injectable sodium salt form of parecoxib, which is a potent and selective inhibitor of cyclo-oxygenase-2 (COX2).",{"v":392.4,"d":"392.40"},"198470-85-8",{"v":78,"d":"78.00"},198.77,{"v":-1,"d":"-1.00"},-2.55,"https://www.selleckchem.com/products/parecoxib-sodium.html","C19H17N2NaO4S","free base","SC-69124 Sodium","CCC(=O)N([Na])[S](=O)(=O)C1=CC=C(C=C1)C2=C(C)ON=C2C3=CC=CC=C3",{"v":3.36,"d":"3.360"},5,0,5]
["S5419","1,4-Cineole","h5","L8000-16","in 10mM DMSO","TRP Channel","Transmembrane Transporters","1,4-Cineole (Isocineole) is a widely distributed, natural, oxygenated monoterpene. 1,4-Cineole, present in eucalyptus oil, activates both human TRPM8 and human TRPA1.",154.25,"470-67-7",{"v":30,"d":"30.00"},194.49,"N/A","N/A","http://selleckchem.com/products/1-4-cineole.html","C10H18O","free base","Isocineole","CC(C)C12CCC(C)(CC1)O2",2.282,1,0,1]
["S5424","Carbaryl","a6","L8000-16","in 10mM DMSO","AChR","Neuronal Signaling","Carbaryl (1-naphthyl methylcarbamate) is a carbamate insecticide and parasiticide and also a potent anticholinesterase agent belonging to the carbamate group of reversible cholinesterase inhibitors.",201.22,"63-25-2",{"v":40,"d":"40.00"},198.79,"N/A","N/A","http://selleckchem.com/products/carbaryl.html","C12H11NO2","free base","1-naphthyl methylcarbamate","CNC(=O)OC1=C2C=CC=CC2=CC=C1",2.502,2,1,2]
["S5428","Promazine hydrochloride","b6","L8000-16","in 10mM DMSO","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Promazine (Romtiazin, Sinophenin) is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine H1-receptors with antipsychotic effects.",320.88,"53-60-1",{"v":64,"d":"64.00"},199.45,"N/A","N/A","http://selleckchem.com/products/promazine-hydrochloride.html","C17H20N2S.HCl","hydrochloride","Romtiazin hydrochloride, Sinophenin hydrochloride","Cl.CN(C)CCCN1C2=CC=CC=C2SC3=C1C=CC=C3",4.457,0,0,4]
["S5435","Quinacrine Dihydrochloride Dihydrate","c6","L8000-16","in 10mM DMSO","Others","Others","Quinacrine (Mepacrine) is a dye of the acridine family that has been widely used as staining agents for DNA and model compounds for intercalators in numerous biophysical studies. It is also an antimalarial drug.",508.91,"6151-30-0",{"v":10,"d":"10.00"},19.65,"N/A","N/A","http://selleckchem.com/products/quinacrine-dihydrochloride-dihydrate.html","C23H30ClN3O.2HCl.2H2O","dihydrochloride, dihydrate","Mepacrine Dihydrochloride Dihydrate","O.O.Cl.Cl.CCN(CC)CCCC(C)NC1=C2C=C(OC)C=CC2=NC3=CC(=CC=C13)Cl",6.015,2,1,9]
["S5447","Triprolidine Hydrochloride","d6","L8000-16","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Triprolidine Hydrochloride is the hydrochloride salt form of Triprolidine, which is the first generation histamine H1 antagonist used in allergic rhinitis.",332.87,"6138-79-0",{"v":62,"d":"62.00"},186.26,"N/A","N/A","http://selleckchem.com/products/triprolidine-hydrochloride.html","C19H22N2.HCl.H2O","hydrochloride, hydrate","N/A","O.Cl.CC1=CC=C(C=C1)\\C(=C/CN2CCCC2)C3=NC=CC=C3",4.249,1,0,4]
["S5452","Sanguinarine chloride","e6","L8000-16","in 10mM DMSO","phosphatase,ROS","Immunology & Inflammation","Sanguinarine, a plant alkaloid, is a potent and specific protein phosphatase (PP) 2C inhibitor. Sanguinarine chloride can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.",367.78,"5578-73-4",{"v":5,"d":"5.00"},{"v":13.6,"d":"13.60"},"<1","N/A","http://selleckchem.com/products/sanguinarine-chloride.html","C20H14NO4.Cl","chloride","N/A","[Cl-].C[N+]1=CC2=C3OCOC3=CC=C2C4=CC=C5C=C6OCOC6=CC5=C14",1.313,4,0,0]
["S5453","Hyperoside","f6","L8000-16","in 10mM DMSO","NF-κB","NF-κB","Hyperoside (Hyperin, Quercetin 3-galactoside), a naturally occuring flavonoid compound, exerts multiple bioactivities, including myocardial protection, anti-redox, and anti-inflammatory activities.Hyperoside can inhibit activation of the NF-κB signaling pathway.",464.38,"482-36-0",{"v":92,"d":"92.00"},198.11,{"v":1,"d":"1.00"},2.15,"http://selleckchem.com/products/hyperoside.html","C21H20O12","free base","Hyperin, Quercetin 3-galactoside","OCC1OC(OC2=C(OC3=C(C(=CC(=C3)O)O)C2=O)C4=CC(=C(O)C=C4)O)C(O)C(O)C1O",{"v":-0.3,"d":"-0.300"},4,8,4]
["S5454","Saikosaponin D","g6","L8000-16","in 10mM DMSO","ATPase","Transmembrane Transporters","Saikosaponin D, a calcium mobilizing agent (SERCA inhibitor), is a type of Saponin derivative, which is a component extracted from Bupleurum falactum. Saikosaponin D has anti-cancer activities.",780.98,"20874-52-6",{"v":100,"d":"100.00"},128.04,"<1","N/A","http://selleckchem.com/products/saikosaponin-d.html","C42H68O13","free base","N/A","CC1OC(OC2CCC3(C)C(CCC4(C)C3C=CC56OCC7(CCC(C)(C)CC57)C(O)CC46C)C2(C)CO)C(O)C(OC8OC(CO)C(O)C(O)C8O)C1O",1.107,5,8,6]
["S5457","Curculigoside","h6","L8000-16","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Curculigoside (Curculigoside A), a diterpenoid triepoxide, is one of the main bioactive phenolic compounds isolated from the rhizome of Curculigo orchioides Gaertn. and has potent antioxidant, anti-osteoporotic, immunomodulatory, and neuroprotective effects.",466.44,"85643-19-2",{"v":93,"d":"93.00"},199.38,{"v":15,"d":"15.00"},32.16,"http://selleckchem.com/products/curculigoside.html","C22H26O11","free base","Curculigoside A","COC1=C(C(=O)OCC2=CC(=CC=C2OC3OC(CO)C(O)C(O)C3O)O)C(=CC=C1)OC",0.822,6,5,9]
["S5458","Verbascoside","a7","L8000-16","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Verbascoside (Acteoside, Kusaginin), a phenylpropanoid glycoside from lemon verbena, has several biological properties such as anti-inflammatory, antimicrobial, antitumor, and antioxidant.",624.59,"61276-17-3",{"v":100,"d":"100.00"},160.11,{"v":100,"d":"100.00"},160.11,"http://selleckchem.com/products/verbascoside.html","C29H36O15","free base","Acteoside, Kusaginin","CC1OC(OC2C(O)C(OCCC3=CC=C(O)C(=C3)O)OC(CO)C2OC(=O)\\C=C\\C4=CC=C(O)C(=C4)O)C(O)C(O)C1O",0.484,6,9,11]
["S5459","Aucubin","b7","L8000-16","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Aucubin (Rhinanthin), an iridoid glycoside existing in medicinal plants, has been reported to show an anti-inflammatory activity by suppression of TNF-α production in murine macrophages.",346.33,"479-98-1",{"v":69,"d":"69.00"},199.23,{"v":15,"d":"15.00"},43.31,"http://selleckchem.com/products/aucubin.html","C15H22O9","free base","Rhinanthin","OCC1OC(OC2OC=CC3C(O)C=C(CO)C23)C(O)C(O)C1O",-2.916,3,6,4]
["S5466","Saikosaponin A","c7","L8000-16","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Saikosaponin A is a triterpene saponin derived from the medicinal plant, Bupleurum chinensis DC. (Umbelliferae). It has a variety of pharmacological benefits, including anti-inﬂammatory, immunomodulatory, and anti-bacterial activities.",780.98,"20736-09-8",{"v":100,"d":"100.00"},128.04,"<1","N/A","https://www.selleckchem.com/products/saikosaponin-a.html","C42H68O13","free base","N/A","CC1OC(OC2CCC3(C)C(CCC4(C)C3C=CC56OCC7(CCC(C)(C)CC57)C(O)CC46C)C2(C)CO)C(O)C(OC8OC(CO)C(O)C(O)C8O)C1O",1.107,5,8,6]
["S5476","Rolapitant","d7","L8000-16","in 10mM DMSO","Neurokinin Receptor","Neuronal Signaling","Rolapitant (SCH-619734) is a selective and competitive antagonist of human substance P/NK1 receptors with antiemetic activity. It has a high affinity for the human NK1 receptor of 0.66 nM and high selectivity over the human NK2 and NK3 subtypes of >1000-fold, as well as preferential affinity for human, guinea pig, gerbil and monkey NK1 receptors over rat, mouse and rabbit.",500.48,"552292-08-7",{"v":100,"d":"100.00"},199.81,"N/A","N/A","https://www.selleckchem.com/products/rolapitant.html","C25H26F6N2O2","NK1 receptor antagonists","SCH-619734","CC(OCC1(CCC2(CCC(=O)N2)CN1)C3=CC=CC=C3)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F",4.761,2,2,7]
["S5479","Cloperastine hydrochloride","e7","L8000-16","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Cloperastine (HT-11) is a drug with a central antitussive effect, and is also endowed with an antihistaminic activity.",366.32,"14984-68-0",{"v":73,"d":"73.00"},199.28,"N/A","N/A","http://selleckchem.com/products/cloperastine-hydrochloride.html","C20H24ClNO.HCl","hydrochloride","HT-11 hydrochloride","Cl.ClC1=CC=C(C=C1)C(OCCN2CCCCC2)C3=CC=CC=C3",5.348,1,0,6]
["S5480","Clidinium Bromide","f7","L8000-16","in 10mM DMSO","AChR","Neuronal Signaling","Clidinium Bromide(Ro 2-3773) is an anticholinergic drug.",432.35,"3485-62-9",{"v":86,"d":"86.00"},198.91,"N/A","N/A","http://selleckchem.com/products/clidinium-bromide.html","C22H26NO3.Br","bromide","Ro 2-3773","[Br-].C[N+]12CCC(CC1)C(C2)OC(=O)C(O)(C3=CC=CC=C3)C4=CC=CC=C4",-0.622,2,0,5]
["S5481","Molindone hydrochloride","g7","L8000-16","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Molindone hydrochloride is the hydrochloride salt form of molindone, a conventional antipsychotic used in the therapy of schizophrenia. It is a dopamine D2/D5 receptor antagonist.",312.83,"15622-65-8",{"v":9,"d":"9.00"},28.77,"N/A","N/A","http://selleckchem.com/products/molindone-hydrochloride.html","C16H24N2O2.HCl","hydrochloride","N/A","Cl.CCC1=C(C)[NH]C2=C1C(=O)C(CC2)CN3CCOCC3",2.522,2,1,3]
["S5485","Desipramine Hydrochloride","h7","L8000-16","in 10mM DMSO","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Desipramine hydrochloride (Desmethylimipramine, Norimipramine, EX-4355, G-35020, JB-8181, NSC-114901) is a dibenzazepine-derivative tricyclic antidepressant that acts as a selective norepinephrine reuptake inhibitor. It also shows weak serotonin reuptake inhibitory, α1-blocking, antihistamine, and anticholinergic effects.",302.84,"58-28-6",{"v":60,"d":"60.00"},198.12,"N/A","N/A","http://selleckchem.com/products/desipramine-hydrochloride.html","C18H22N2.HCl","hydrochloride","Desmethylimipramine, Norimipramine, EX-4355, G-35020, JB-8181, NSC-114901","Cl.CNCCCN1C2=C(CCC3=C1C=CC=C3)C=CC=C2",4.234,0,1,4]
["S5486","Fluorometholone","a8","L8000-16","in 10mM DMSO","Glucocorticoid Receptor","Endocrinology & Hormones","Fluorometholone (Oxylone) is a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. It is usually used as eye drops in the treatment of allergic and inflammatory conditions of the eye.",376.46,"426-13-1",{"v":75,"d":"75.00"},199.22,"<1","N/A","http://selleckchem.com/products/fluorometholone.html","C22H29FO4","free base","Oxylone","CC1CC2C3CCC(O)(C(C)=O)C3(C)CC(O)C2(F)C4(C)C=CC(=O)C=C14",2.312,2,1,1]
["S5487","Cefoperazone sodium","b8","L8000-16","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Cefoperazone Sodium(CP 52640-2) is the sodium salt form of cefoperazone, which is a semi-synthetic, broad-spectrum, beta-lactamase resistant antibiotic with bactericidal activity.",667.65,"62893-20-3",{"v":100,"d":"100.00"},149.78,{"v":-1,"d":"-1.00"},{"v":-1.5,"d":"-1.50"},"https://www.selleckchem.com/products/cefoperazone-sodium.html","C25H26N9NaO8S2","free base","CP 52640-2","[Na+].CCN1CCN(C(=O)NC(C(=O)NC2C3SCC(=C(N3C2=O)C([O-])=O)CSC4=NN=N[N]4C)C5=CC=C(O)C=C5)C(=O)C1=O",-2.266,8,3,9]
["S5488","Fluorescein","c8","L8000-16","in 10mM DMSO","Dyes","Others","Fluorescein (Solvent Yellow 94, Resorcinolphthalein, Yellow fluorescein) is a manufactured organic compound and dye.",332.31,"2321-07-5",{"v":67,"d":"67.00"},201.62,{"v":-1,"d":"-1.00"},-3.01,"https://www.selleckchem.com/products/fluorescein.html","C20H12O5","free base","Solvent Yellow 94, Resorcinolphthalein, Yellow fluorescein","OC1=CC2=C(C=C1)C3(OC(=O)C4=C3C=CC=C4)C5=C(O2)C=C(O)C=C5",3.737,3,2,0]
["S5490","Disopyramide","d8","L8000-16","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Disopyramide is a class IA antiarrhythmic drug which acts via blockade of sodium channels depressing phase 0 of the action potential. Disopyramide possesses significant negative inotropic, anticholinergic effects and enhances AV nodal conduction.",339.47,"3737-09-5",{"v":67,"d":"67.00"},197.37,"N/A","N/A","http://selleckchem.com/products/disopyramide.html","C21H29N3O","Antiarrhythmic agent ","N/A","CC(C)N(CCC(C(N)=O)(C1=CC=CC=C1)C2=NC=CC=C2)C(C)C",3.417,2,1,8]
["S5491","Lomefloxacin","e8","L8000-16","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Lomefloxacin(SC47111A) is a fluoroquinolone antibiotic used to treat bacterial infections.",351.35,"98079-51-7",{"v":7,"d":"7.00"},19.92,{"v":-1,"d":"-1.00"},-2.85,"https://www.selleckchem.com/products/lomefloxacin.html","C17H19F2N3O3","free base","SC47111A","CCN1C=C(C(O)=O)C(=O)C2=C1C(=C(N3CCNC(C)C3)C(=C2)F)F",-0.828,2,1,3]
["S5492","Econazole","f8","L8000-16","in 10mM DMSO","Bacterial","Microbiology","Econazole is a broad spectrum antimycotic with some action against Gram positive bacteria.",381.68,"27220-47-9",{"v":76,"d":"76.00"},199.12,"N/A","N/A","http://selleckchem.com/products/econazole.html","C18H15Cl3N2O","free base","N/A","ClC1=CC=C(COC(C[N]2C=CN=C2)C3=C(Cl)C=C(Cl)C=C3)C=C1",4.981,2,0,6]
["S5493","Atropine sulfate","g8","L8000-16","in 10mM DMSO","AChR","Neuronal Signaling","Atropine Sulfate (Sulfatropinol, Atropette, Tropintran) is the sulfate salt of atropine, which is a natural alkaloid anticholinergic agent and has potent antimuscarinic effects.",676.82,"55-48-1",{"v":18,"d":"18.00"},26.59,"N/A","N/A","https://www.selleckchem.com/products/atropine-sulfate.html","C34H46N2O6.H2SO4","sulfate","Sulfatropinol, Atropette, Tropintran","CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN4C5CCC4CC(C5)OC(=O)C(CO)C6=CC=CC=C6.O[S](O)(=O)=O",2.835,4,2,10]
["S5494","Salbutamol","h8","L8000-16","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Salbutamol (Albuterol) is a short-acting, selective beta2-adrenergic receptor agonist used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases.",239.31,"18559-94-9",{"v":47,"d":"47.00"},{"v":196.4,"d":"196.40"},"N/A","N/A","https://www.selleckchem.com/products/salbutamol.html","C13H21NO3","free base","Albuterol","CC(C)(C)NCC(O)C1=CC=C(O)C(=C1)CO",0.941,0,4,5]
["S5498","Betahistine mesylate","a9","L8000-16","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Betahistine mesylate is the mesylate salt form of Betahistine, a histamine analog and H3 receptor agonist that serves as a vasodilator.",328.41,"54856-23-4",{"v":65,"d":"65.00"},197.92,"N/A","N/A","http://selleckchem.com/products/betahistine-mesylate.html","C8H12N2.2CH4O3S","dimethanesulfonate","N/A","CNCCC1=CC=CC=N1.C[S](O)(=O)=O.C[S](O)(=O)=O",-0.148,1,1,3]
["S5502","Ilaprazole sodium","b9","L8000-16","in 10mM DMSO","ATPase,Proton Pump","Transmembrane Transporters","Ilaprazole (IY-81149) sodium is the sodium salt form of ilaprazole, which is a proton pump inhibitor. Ilaprazole sodium irreversibly inhibits H(+)/K(+)-ATPase in a dose-dependent manner with IC50 of 6 μM in rabbit parietal cell preparation.",388.42,"172152-50-0",{"v":78,"d":"78.00"},200.81,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/iiaprazole-sodium.html","C19H17N4NaO2S","Sodium Salt","IY-81149 sodium","COC1=C(C)C(=NC=C1)C[S](=O)C2=NC3=C(C=CC(=C3)[N]4C=CC=C4)[N]2[Na]",3.414,4,0,5]
["S5504","Ropivacaine","c9","L8000-16","in 10mM DMSO","Others","Others","Ropivacaine is a member of the amino amide class of local anesthetics.",{"v":274.4,"d":"274.40"},"84057-95-4",{"v":23,"d":"23.00"},83.82,"<1","N/A","https://www.selleckchem.com/products/ropivacaine.html","C17H26N2O","Amide local anesthetics","N/A","CCCN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",3.853,1,1,4]
["S5507","Trimebutine maleate","e9","L8000-16","in 10mM DMSO","Opioid Receptor","Neuronal Signaling","Trimebutine maleate is the maleate salt form of trimebutine, which is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects.",503.54,"34140-59-5",{"v":100,"d":"100.00"},198.59,{"v":-1,"d":"-1.00"},-1.99,"https://www.selleckchem.com/products/trimebutine-maleate.html","C26H33NO9","Maleate salt","3, 4, 5-Trimethoxybenzoic Acid 2-(Dimethylamino)-2-phenylbutyl Ester Maleate Salt;","CCC(COC(=O)C1=CC(=C(OC)C(=C1)OC)OC)(N(C)C)C2=CC=CC=C2.OC(=O)\\C=C/C(O)=O",{"v":1.12,"d":"1.120"},7,0,12]
["S5527","Salmeterol","g9","L8000-16","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Salmeterol (Astmerole, GR-33343X, SN408D) is a long-acting beta2-adrenergic receptor agonist with Ki value of 1.5 nM for WT β2AR and shows very high selectivity for the WT β2AR(β1Ki/β2Ki ratio of approximately 1500).",415.57,"89365-50-4",{"v":83,"d":"83.00"},199.73,"<1","N/A","http://selleckchem.com/products/salmeterol.html","C25H37NO4","free base","Astmerole, GR-33343X, SN408D","OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC2=CC=CC=C2",4.251,1,4,16]
["S5535","Moxifloxacin","h9","L8000-16","in 10mM DMSO","Antibiotics,Bacterial","Microbiology","Moxifloxacin is an antibiotic used to treat a number of bacterial infections, active against Mycobacterium tuberculosis in vitro.",401.43,"151096-09-2",{"v":24,"d":"24.00"},59.79,{"v":-1,"d":"-1.00"},-2.49,"https://www.selleckchem.com/products/moxifloxacin.html","C21H24FN3O4","free base","BAY12-8039","COC1=C2N(C=C(C(O)=O)C(=O)C2=CC(=C1N3CC4CCCNC4C3)F)C5CC5",-0.702,3,1,4]
["S5537","Tizanidine","a10","L8000-16","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Tizanidine is an imidazoline derivative and a centrally acting α2 adrenergic agonist used as a muscle relaxant for therapy of acute muscle spasms and chronic spasticity.",253.71,"51322-75-9",{"v":50,"d":"50.00"},197.07,{"v":15,"d":"15.00"},59.12,"http://selleckchem.com/products/tizanidine.html","C9H8ClN5S","α2-adrenergic agonists","N/A","ClC1=C(NC2=NCCN2)C3=NSN=C3C=C1",1.817,3,2,2]
["S5538","Tropisetron","b10","L8000-16","in 10mM DMSO","5-HT Receptor,AChR","Neuronal Signaling","Tropisetron (ICS 205-930) is a 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.",284.35,"89565-68-4",{"v":10,"d":"10.00"},35.17,{"v":56,"d":"56.00"},196.94,"http://selleckchem.com/products/tropisetron.html","C17H20N2O2","free base","ICS 205-930","CN1C2CCC1CC(C2)OC(=O)C3=C[NH]C4=C3C=CC=C4",2.608,2,1,3]
["S5544","D-Ribose","c10","L8000-16","in 10mM DMSO","Others","Others","D-ribose is a naturally occurring sugar involved in producing energy in the body and is also the structural basis of DNA and RNA.",150.13,"50-69-1",{"v":30,"d":"30.00"},199.83,"N/A","N/A","http://selleckchem.com/products/d-ribose.html","C5H10O5","free base","N/A","OCC(O)C(O)C(O)C=O",{"v":-2.28,"d":"-2.280"},1,4,4]
["S5550","Ethyl gallate","d10","L8000-16","in 10mM DMSO","Bcl-2,Caspase","Apoptosis","Ethyl gallat (Phyllemblin, gallic acid ethyl ester), which could be found naturally in a variety of plant sources, is a food additive with antimicrobial activity. Ethyl gallat activates the death receptor-dependent pathway of apoptosis by enhancing the expression of caspases-8, -9, and -3 and the Bcl-2 interacting domain (Bid).",198.17,"831-61-8",{"v":39,"d":"39.00"},{"v":196.8,"d":"196.80"},"N/A","N/A","https://www.selleckchem.com/products/ethyl-gallate.html","C9H10O5","Ester","Phyllemblin, gallic acid ethyl ester","CCOC(=O)C1=CC(=C(O)C(=C1)O)O",1.308,2,3,3]
["S5552","Amenamevir","e10","L8000-16","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Amenamevir (ASP2151) is a potent helicase-primase inhibitor and a novel class of antiviral agent.",482.55,"841301-32-4","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/amenamevir.html","C24H26N4O5S","free base","ASP2151","CC1=C(N(CC(=O)NC2=CC=C(C=C2)C3=NOC=N3)C(=O)C4CC[S](=O)(=O)CC4)C(=CC=C1)C",{"v":2.24,"d":"2.240"},7,1,6]
["S5554","Lanatoside C","f10","L8000-16","in 10mM DMSO","Akt,Antiviral,Apoptosis related,Autophagy,JAK,mTOR,PI3K,STAT,Wnt/beta-catenin","Immunology & Inflammation","Lanatoside C is a cardiac glycoside with antiviral and anti-tumor activity. Lanatoside C induces G2/M cell cycle arrest and induces autophagy and apoptosis via attenuating MAPK, Wnt, JAK-STAT, and PI3K/AKT/mTOR signaling pathways.",985.12,"17575-22-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/lanatoside-c.html","C49H76O20","free base","N/A","CC1OC(CC(O)C1OC2CC(O)C(OC3CC(OC(C)=O)C(OC4OC(CO)C(O)C(O)C4O)C(C)O3)C(C)O2)OC5CCC6(C)C(CCC7C6CC(O)C8(C)C(CCC78O)C9=CC(=O)OC9)C5",0.631,12,7,12]
["S5556","(-)-Sparteine Sulfate","g10","L8000-16","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Sparteine Sulfate, a quinolizidine alkaloid, is the sulfate form of sparteini, which is a sodium channel blocker used as an oxytocic and an anti-arrhythmia agent.",422.54,"6160-12-9","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/sparteini-sulfas.html","C15H26N2.H2SO4.5H2O","sulfate pentahydrate","N/A","O.O.O.O.O.O[S](O)(=O)=O.C1CCN2CC3CC(CN4CCCCC34)C2C1",{"v":0.72,"d":"0.720"},0,0,0]
["S5561","Ethacrynic Acid","h10","L8000-16","in 10mM DMSO","Others","NF-κB","Ethacrynic Acid is a loop or high ceiling diuretic used for the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.",303.14,"58-54-8",{"v":61,"d":"61.00"},201.23,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/ethacrynic-acid.html","C13H12Cl2O4","Free Base","N/A","CCC(=C)C(=O)C1=C(Cl)C(=C(OCC(O)=O)C=C1)Cl",3.963,3,0,6]
["S5563","Thioridazine hydrochloride","a11","L8000-16","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Thioridazine (Aldazine, Mellaril) is a potent antianxiety and antipsychotic agent.",407.04,"130-61-0",{"v":81,"d":"81.00"},{"v":199,"d":"199.00"},"N/A","N/A","http://selleckchem.com/products/thioridazine-hydrochloride.html","C21H26N2S2.HCl","hydrochloride","Aldazine, Mellaril","Cl.CSC1=CC2=C(SC3=CC=CC=C3N2CCC4CCCCN4C)C=C1",5.945,0,0,4]
["S5564","Xylazine","b11","L8000-16","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Xylazine is a partial alpha-2 adrenergic agonist that is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals.",220.33,"7361-61-7",{"v":44,"d":"44.00"},{"v":199.7,"d":"199.70"},{"v":-1,"d":"-1.00"},-4.54,"https://www.selleckchem.com/products/xylazine.html","C12H16N2S","free base","N/A","CC1=C(NC2=NCCCS2)C(=CC=C1)C",3.265,1,1,2]
["S5566","Dapagliflozin propanediol monohydrate","c11","L8000-16","in 10mM DMSO","SGLT","GPCR & G Protein","Dapagliflozin propanediol belongs to the class of orally administered antidiabetic agents designated as sodiumglucose cotransporter 2 (SGLT2) inhibitors.",502.98,"960404-48-2",{"v":100,"d":"100.00"},198.82,"<1","N/A","http://selleckchem.com/products/dapagliflozin-propanediol-monohydrate.html","C21H25ClO6.C3H8O2.H2O","monohydrate","N/A","O.CCOC1=CC=C(CC2=C(Cl)C=CC(=C2)C3OC(CO)C(O)C(O)C3O)C=C1.CC(O)CO",1.682,2,6,7]
["S5573","Tilmicosin phosphate","d11","L8000-16","in 10mM DMSO","Antibiotics","Microbiology","Tilmicosin phosphate is a macrolide antibiotic that is used to treat cattle for pathogens that cause Bovine Respiratory Disease.",967.13,"137330-13-3",{"v":100,"d":"100.00"},{"v":103.4,"d":"103.40"},"N/A","N/A","http://selleckchem.com/products/tilmicosin-phosphate.html","C46H80N2O13.H3O4P","phosphate","N/A","CCC1OC(=O)CC(O)C(C)C(OC2OC(C)C(O)C(C2O)N(C)C)C(CCN3CC(C)CC(C)C3)CC(C)C(=O)\\C=C\\C(=C\\C1COC4OC(C)C(O)C(OC)C4OC)C.O[P](O)(O)=O",3.392,9,4,12]
["S5582","Cytarabine hydrochloride","e11","L8000-16","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Cytarabine is a pyrimidine nucleoside analog that is used mainly in the treatment of leukemia. It is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA.",279.68,"69-74-9",{"v":55,"d":"55.00"},196.65,"N/A","N/A","http://selleckchem.com/products/cytarabine-hydrochloride.html","C9H13N3O5.HCl","hydrochloride","N/A","Cl.NC1=NC(=O)N(C=C1)C2OC(CO)C(O)C2O",-2.014,3,4,2]
["S5592","Vitamin A","f11","L8000-16","in 10mM DMSO","Vitamin","Metabolism","Vitamin A (Retinol) is a naturally occuring fat-soluble vitamin that is important for normal vision, the immune system, and reproduction. It also plays roles in normal functioning of heart, lungs, kidneys, and other organs.",286.45,"68-26-8",{"v":57,"d":"57.00"},198.99,{"v":-1,"d":"-1.00"},-3.49,"https://www.selleckchem.com/products/vitamin-a.html","C20H30O","free base","Retinol","CC(=C/CO)\\C=C\\C=C(C)\\C=C\\C1=C(C)CCCC1(C)C",5.316,0,1,5]
["S5623","Bedaquiline","g11","L8000-16","in 10mM DMSO","ATPase","Transmembrane Transporters","Bedaquiline (TMC-207, R207910), a diarylquinoline, binds to subunit c of mycobacterial ATP synthase and inhibits its activity. It is highly selective for mycobacterial ATP synthase enzyme compared to homologous eukaryotic enzyme (Selectivity Index >20 000).",{"v":555.5,"d":"555.50"},"843663-66-1",{"v":12,"d":"12.00"},{"v":21.6,"d":"21.60"},"<1","N/A","https://www.selleckchem.com/products/bedaquiline.html","C32H31BrN2O2","free base","TMC-207, R207910","COC1=NC2=CC=C(Br)C=C2C=C1C(C3=CC=CC=C3)C(O)(CCN(C)C)C4=CC=CC5=CC=CC=C45",6.933,2,0,8]
["S5625","Ammonium lactate","h11","L8000-16","in 10mM DMSO","Bacterial","Microbiology","Ammonium lactate (Lac-hydrin) is the ammonium salt of lactic acid with mild anti-bacterial properties.",107.11,"515-98-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",{"v":10,"d":"10.00"},"N/A",{"v":0,"d":"0.00"},"https://www.selleckchem.com/products/ammonium-iactate.html","C3H9NO3","free base","Lac-hydrin","[NH4+].CC(O)C([O-])=O",-3.725,0,1,1]
["S5627","Amsacrine hydrochloride","a2","L8000-17","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Amsacrine hydrochloride (m-AMSA, acridinyl anisidide) is the hydrochloride salt form of amsacrine, which is an inhibitor of topoisomerase II with antineoplastic activity.",429.92,"54301-15-4",{"v":85,"d":"85.00"},197.71,"N/A",{"v":0,"d":"0.00"},"https://www.selleckchem.com/products/amsacrine-hydrochloride.html","C21H20ClN3O3S","free base","m-AMSA, acridinyl anisidide","Cl.COC1=CC(=CC=C1NC2=C3C=CC=CC3=NC4=C2C=CC=C4)N[S](C)(=O)=O",{"v":4.18,"d":"4.180"},4,2,5]
["S5649","Hydroxyzine pamoate","b2","L8000-17","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Hydroxyzine Pamoate is the pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties.",763.27,"10246-75-0",{"v":100,"d":"100.00"},131.01,{"v":-1,"d":"-1.00"},-1.31,"https://www.selleckchem.com/products/hydroxyzine-pamoate.html","C44H43ClN2O8","free base","N/A","OCCOCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3.OC(=O)C4=C(O)C(=C5C=CC=CC5=C4)CC6=C7C=CC=CC7=CC(=C6O)C(O)=O",1.794,3,3,12]
["S5651","Dexrazoxane","c2","L8000-17","in 10mM DMSO","Others","Others","Dexrazoxane (ICRF-187) is an anticancer drug able to block mitosis and to arrest dividing cells. It is an iron chelator and provides cardioprotection against anthracycline toxicity.",268.27,"24584-09-6",{"v":54,"d":"54.00"},201.29,"<1","N/A","http://selleckchem.com/products/dexrazoxane.html","C11H16N4O4","free base","ICRF-187","CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2",-2.104,4,2,3]
["S5654","Indacaterol","d2","L8000-17","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor.",392.49,"312753-06-3",{"v":52,"d":"52.00"},132.49,"<1","N/A","http://selleckchem.com/products/indacaterol.html","C24H28N2O3","free base","N/A","CCC1=CC2=C(CC(C2)NCC(O)C3=CC=C(O)C4=C3C=CC(=O)N4)C=C1CC",{"v":3.93,"d":"3.930"},1,4,6]
["S5656","Diphenylpyraline hydrochloride","e2","L8000-17","in 10mM DMSO","Dyes,Histamine Receptor","Neuronal Signaling","Diphenylpyraline hydrochloride is the hydrochloride salt form of diphenylpyraline, which is an antihistamine used in the treatment of allergic rhinitis, hay fever, and allergic skin disorders.",317.85,"132-18-3",{"v":63,"d":"63.00"},198.21,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/diphenylpyraline-hydrochloride.html","C19H24ClNO","hydrochloride","N/A","Cl.CN1CCC(CC1)OC(C2=CC=CC=C2)C3=CC=CC=C3",3.738,1,0,4]
["S5657","Ertapenem sodium","f2","L8000-17","in 10mM DMSO","Antibiotics","Microbiology","Ertapenem Sodium (MK826) is the sodium salt of ertapenem, a long-acting, broad-spectrum antibiotic of β-lactam subclass.",{"v":497.5,"d":"497.50"},"153773-82-1",{"v":100,"d":"100.00"},201.01,{"v":100,"d":"100.00"},201.01,"http://selleckchem.com/products/ertapenem-sodium.html","C22H24N3NaO7S","sodium salt","MK826","[Na+].CC(O)C1C2C(C)C(=C(N2C1=O)C([O-])=O)SC3CNC(C3)C(=O)NC4=CC(=CC=C4)C(O)=O",-4.602,3,3,7]
["S5658","Omeprazole Sodium","g2","L8000-17","in 10mM DMSO","P450 (e.g. CYP17),Proton Pump","Transmembrane Transporters","Omeprazole Sodium is the sodium salt form of omeprazole, which is a proton pump inhibitor and suppresses gastric acid secretion. Omeprazole Sodium is a metabolism-dependent inhibitor (MDI) of CYP2C19.",{"v":367.4,"d":"367.40"},"95510-70-6",{"v":73,"d":"73.00"},198.69,{"v":73,"d":"73.00"},198.69,"http://www.selleckchem.com/products/omeprazole-sodium.html","C17H18N3NaO3S","Sodium Salt","N/A","COC1=CC2=C(C=C1)[N]([Na])C(=N2)[S](=O)CC3=NC=C(C)C(=C3C)OC",3.008,5,0,5]
["S5659","Emedastine","h2","L8000-17","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Emedastine is a potent, high affinity histamine H1-receptor-selective antagonist with Ki of 1.3 ±0.1 nM for H1-receptors while considerably weaker at H2- (K1 = 49,067 ± 11,113 nM) and H3-receptors (Ki = 12,430 ± 1,282 nM).",302.41,"87233-61-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",{"v":10,"d":"10.00"},"N/A","N/A","http://selleckchem.com/products/emedastine.html","C17H26N4O","free base","N/A","CCOCC[N]1C2=C(C=CC=C2)N=C1N3CCCN(C)CC3",2.492,2,0,5]
["S5662","Ranitidine","a3","L8000-17","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Ranitidine(AH-19065) is an H2 histamine receptor antagonist that works by blocking histamine and thus decreasing the amount of acid released by cells of the stomach.",{"v":314.4,"d":"314.40"},"66357-35-5",{"v":63,"d":"63.00"},200.38,{"v":-1,"d":"-1.00"},-3.18,"https://www.selleckchem.com/products/ranitidine.html","C13H22N4O3S","free base","AH-19065","CNC(/NCCSCC1=CC=C(CN(C)C)O1)=C\\[N+]([O-])=O",1.039,1,2,10]
["S5663","Minaprine dihydrochloride","b3","L8000-17","in 10mM DMSO","MAO","Metabolism","Minaprine dihydrochloride is hydrochloride salt form of Minaprine, which acts as a reversible inhibitor of MAO-A in rats and weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.",{"v":371.3,"d":"371.30"},"25905-77-5",{"v":74,"d":"74.00"},{"v":199.3,"d":"199.30"},{"v":74,"d":"74.00"},{"v":199.3,"d":"199.30"},"https://www.selleckchem.com/products/minaprine-dihydrochloride.html","C17H24Cl2N4O","free base","N/A","Cl.Cl.CC1=CC(=NN=C1NCCN2CCOCC2)C3=CC=CC=C3",3.583,3,1,5]
["S5664","Orphenadrine Hydrochloride","c3","L8000-17","in 10mM DMSO","NMDAR","Neuronal Signaling","Orphenadrine Hydrochloride is an uncompetitive NMDAR antagonist, H1 receptor antagonist and nonselective mAChR antagonist with muscle relaxant activity.",305.84,"341-69-5",{"v":61,"d":"61.00"},199.45,{"v":-1,"d":"-1.00"},-3.27,"https://www.selleckchem.com/products/orphenadrine-hydrochloride.html","C18H24ClNO","free base","N/A","Cl.CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2C",4.253,1,0,6]
["S5665","Drofenine Hydrochloride","d3","L8000-17","in 10mM DMSO","BChE","Neuronal Signaling","Drofenine hydrochloride is a potent competitive inhibitor of BChE. It is an anticholinergic that acts both at the level of the nerves and the muscle fibers.",353.93,"548-66-3",{"v":71,"d":"71.00"},{"v":200.6,"d":"200.60"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/drofenine-hydrochloride.html","C20H32ClNO2","hydrochloride","N/A","Cl.CCN(CC)CCOC(=O)C(C1CCCCC1)C2=CC=CC=C2",5.106,2,0,9]
["S5666","Moxisylyte hydrochloride","e3","L8000-17","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Moxisylyte hydrochloride (thymoxamine) is an alpha-adrenergic blocking agent used for the treatment of Raynaud's disease.",315.84,"964-52-3",{"v":63,"d":"63.00"},199.47,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/moxisylyte-hydrochloride.html","C16H26ClNO3","hydrochloride","thymoxamine hydrochloride","Cl.CC(C)C1=C(OCCN(C)C)C=C(C)C(=C1)OC(C)=O",3.782,3,0,7]
["S5667","Fruquintinib (HMPL-013)","f3","L8000-17","in 10mM DMSO","VEGFR","Angiogenesis","Fruquintinib (HMPL-013) is a small molecule inhibitor with strong potency and high selectivity against VEGFR family. It inhibits VEGFR 1, 2, 3, with IC50 values of 33 nM, 35 nM and 0.5 nM, respectively and shows only weak inhibition of RET, FGFR-1 and c-kit kinases.",393.39,"1194506-26-7",{"v":6,"d":"6.00"},15.25,"<1","N/A","https://www.selleckchem.com/products/fruquintinib.html","C21H19N3O5","Tyrosine kinase inhibitor","N/A","CNC(=O)C1=C(C)OC2=CC(=CC=C12)OC3=C4C=C(OC)C(=CC4=NC=N3)OC",3.111,7,1,5]
["S5669","Isoxsuprine hydrochloride","g3","L8000-17","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Isoxsuprine hydrochloride is a beta-adrenergic agonist with vasodilator activity.",337.84,"579-56-6",{"v":68,"d":"68.00"},201.28,{"v":4,"d":"4.00"},11.84,"http://www.selleckchem.com/products/isoxsuprine-hydrochloride.html","C18H24ClNO3","hydrochloride","N/A","Cl.CC(COC1=CC=CC=C1)NC(C)C(O)C2=CC=C(O)C=C2",3.384,1,3,7]
["S5670","Chloropyramine hydrochloride","h3","L8000-17","in 10mM DMSO","Histamine Receptor","Neuronal Signaling","Chloropyramine hydrochloride (Halopyramine) is a histamine receptor H1 antagonist and has anti-cholinergic, antispasmodic, and antiallergic effects.",326.26,"6170-42-9",{"v":65,"d":"65.00"},199.23,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/chloropyramine-hydrochloride.html","C16H21Cl2N3","hydrochloride","Halopyramine hydrochloride","Cl.CN(C)CCN(CC1=CC=C(Cl)C=C1)C2=CC=CC=N2",4.149,1,0,6]
["S5683","Isoproterenol sulfate dihydrate","a4","L8000-17","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Isoproterenol Sulfate is the sulfate salt form of isoproterenol, a beta-adrenergic receptor agonist with bronchodilator activity.",556.62,"299-95-6",{"v":100,"d":"100.00"},179.66,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/isoproterenol-sulfate-dihydrate.html","C22H40N2O12S","dihydrate","N/A","O.O.CC(C)NCC(O)C1=CC=C(O)C(=C1)O.CC(C)NCC(O)C2=CC=C(O)C(=C2)O.O[S](O)(=O)=O",1.177,0,8,8]
["S5698","Ketorolac tromethamine salt","b4","L8000-17","in 10mM DMSO","COX","Immunology & Inflammation","Ketorolac tromethamine is a synthetic pyrrolizine carboxylic acid derivative with anti-inflammatory, analgesic and antipyretic properties. It is a non-selective COX inhibitor with IC50s of 20 nM for both COX-1 and COX-2.",{"v":376.4,"d":"376.40"},"74103-07-4",{"v":75,"d":"75.00"},199.26,{"v":75,"d":"75.00"},199.26,"http://www.selleckchem.com/products/ketorolac-tromethamine-salt.html","C19H24N2O6","tromethamine salt","N/A","NC(CO)(CO)CO.OC(=O)C1CC[N]2C1=CC=C2C(=O)C3=CC=CC=C3",-2.028,2,4,6]
["S5703","Carvedilol Phosphate","c4","L8000-17","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity.",513.48,"610309-89-2",{"v":100,"d":"100.00"},198.23,{"v":-1,"d":"-1.00"},-1.98,"https://www.selleckchem.com/products/carvedilol-phosphate.html","C24H29N2O8P.1/2H2O","Phosphate","N/A","COC1=C(OCCNCC(O)COC2=CC=CC3=C2C4=C([NH]3)C=CC=C4)C=CC=C1.O[P](O)(O)=O",{"v":4.28,"d":"4.280"},3,3,10]
["S5705","Raceanisodamine","d4","L8000-17","in 10mM DMSO","Others","Others","Raceanisodamine (7β-Hydroxyhyoscyamine) is the active ingredient of Chinese herbal extracts that has vasoactive activity used to treat acute disseminated intravascular coagulation in patients in bacteremic shock.",305.37,"17659-49-3",{"v":61,"d":"61.00"},199.76,{"v":30,"d":"30.00"},98.24,"http://selleckchem.com/products/raceanisodamine.html","C17H23NO4","free base","7β-Hydroxyhyoscyamine","CN1C2CC(O)C1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",{"v":0.63,"d":"0.630"},2,2,5]
["S5709","Norgestrel","e4","L8000-17","in 10mM DMSO","ROS","Immunology & Inflammation","Norgestrel (WY-3707, SH-70850, SH-850, FH 122-A) is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception. It also has strong neuroprotective activity.",312.45,"6533-00-2",{"v":62,"d":"62.00"},198.43,"<1","N/A","http://selleckchem.com/products/norgestrel.html","C21H28O2","free base","WY-3707, SH-70850, SH-850, FH 122-A","CCC12CCC3C(CCC4=CC(=O)CCC34)C1CCC2(O)C#C",4.771,1,0,1]
["S5710","Ambroxol","f4","L8000-17","in 10mM DMSO","Sodium Channel","Transmembrane Transporters","Ambroxol, a substituted benzylamine, is an active metabolite of bromhexine. It is a potent inhibitor of the neuronal Na+ channels.",{"v":378.1,"d":"378.10"},"18683-91-5",{"v":76,"d":"76.00"},{"v":201,"d":"201.00"},{"v":-1,"d":"-1.00"},-2.64,"https://www.selleckchem.com/products/ambroxol.html","C13H18Br2N2O","Expectorant","N/A","NC1=C(Br)C=C(Br)C=C1CNC2CCC(O)CC2",2.739,0,3,3]
["S5713","Pravastatin","g4","L8000-17","in 10mM DMSO","HMG-CoA Reductase","Metabolism","Pravastatin(CS-514) is a lipoprotein-lowering drug via reversibly inhibiting hydroxymethylglutaryl-CoA (HMG-CoA) reductase and the synthesis of very-low-density lipoproteins.",424.53,"81093-37-0",{"v":85,"d":"85.00"},200.22,{"v":85,"d":"85.00"},200.22,"http://www.selleckchem.com/products/pravastatin.html","C23H36O7","Free Base","CS-514","CCC(C)C(=O)OC1CC(O)C=C2C=CC(C)C(CCC(O)CC(O)CC(O)=O)C12",2.156,3,3,11]
["S5714","lurasidone","h4","L8000-17","in 10mM DMSO","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Lurasidone (SM-13496) is a second-generation antipsychotic agent that exhibits full antagonism at dopamine D2 and serotonin 5-HT2A receptors with binding affinities Ki = 1 nM and Ki = 0.5 nM, respectively. It also has high affinity for serotonin 5-HT7 receptors (Ki = 0.5 nM), partial agonist activity at 5-HT1A receptors (Ki = 6.4 nM) and lacks affinity for histamine H1 and muscarinic M1 receptors.",492.68,"367514-87-2",{"v":7,"d":"7.00"},14.21,"<1","N/A","http://selleckchem.com/products/lurasidone.html","C28H36N4O2S","free base","SM-13496","O=C1C2C3CCC(C3)C2C(=O)N1CC4CCCCC4CN5CCN(CC5)C6=NSC7=CC=CC=C67",4.896,3,0,5]
["S5715","Atorvastatin","a5","L8000-17","in 10mM DMSO","Autophagy,HMG-CoA Reductase","Metabolism","Atorvastatin is a lipid lowering agent. It is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the rate-determining enzyme in cholesterol biosynthesis via the mevalonate pathway. Atorvastatin activates autophagy.",558.64,"134523-00-5",{"v":100,"d":"100.00"},179.01,"<1","N/A","http://www.selleckchem.com/products/atorvastatin.html","C33H35FN2O5","Free Base","N/A","CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C([N]1CCC(O)CC(O)CC(O)=O)C3=CC=C(F)C=C3)C4=CC=CC=C4",5.555,2,3,12]
["S5716","Abemaciclib (LY2835219)","b5","L8000-17","in 10mM DMSO","CDK","Cell Cycle","Abemaciclib (LY2835219) is a cell cycle inhibitor selective for CDK4/6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively.",506.59,"1231929-97-7",{"v":6,"d":"6.00"},11.84,"<1","N/A","http://selleckchem.com/products/abemaciclib.html","C27H32F2N8","free base","LY2835219","CCN1CCN(CC1)CC2=CN=C(NC3=NC=C(F)C(=N3)C4=CC(=C5N=C(C)[N](C(C)C)C5=C4)F)C=C2",4.957,4,1,7]
["S5717","Acetohexamide","c5","L8000-17","in 10mM DMSO","Others","Others","Acetohexamide is an intermediate-acting, first-generation oral sulfonylurea with hypoglycemic activity. It exerts the blood-glucose-lowering effects by stimulating the pancreatic beta cells to secrete insulin and by helping the body use insulin efficiently.",{"v":324.4,"d":"324.40"},"968-81-0",{"v":11,"d":"11.00"},33.91,"<1","N/A","http://selleckchem.com/products/acetohexamide.html","C15H20N2O4S","free base","N/A","CC(=O)C1=CC=C(C=C1)[S](=O)(=O)NC(=O)NC2CCCCC2",2.119,4,2,4]
["S5727","Tetryzoline","d5","L8000-17","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Tetryzoline (Tetrahydrozoline) is an alpha-adrenergic agonist used in some over-the-counter eye drops and nasal sprays.",200.28,"84-22-0",{"v":40,"d":"40.00"},199.72,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/tetryzoline.html","C13H16N2","Free Base","Tetrahydrozoline","C1CC(C2=NCCN2)C3=C(C1)C=CC=C3",2.185,1,1,1]
["S5728","Delapril Hydrochloride","e5","L8000-17","in 10mM DMSO","ACE,RAAS","Endocrinology & Hormones","Delapril Hydrochloride (Alindapril) is the hydrochloride salt form of delapril, which is a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.",{"v":489,"d":"489.00"},"83435-67-0",{"v":98,"d":"98.00"},200.41,"<1","N/A","https://www.selleckchem.com/products/delapril-hydrochloride.html","C26H33ClN2O5","hydrochloride","Alindapril Hydrochloride","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N(CC(O)=O)C2CC3=C(C2)C=CC=C3",1.253,4,1,12]
["S5729","Fosfosal","f5","L8000-17","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Fosfosal (2-phosphonoxy benzoic acid) is a non-acetylated salicylic acid derivative, with analgesic and anti-inflammatory activity, but without effects on PG biosynthesis in vitro.",{"v":218.1,"d":"218.10"},"6064-83-1",{"v":43,"d":"43.00"},197.16,{"v":-1,"d":"-1.00"},-4.59,"https://www.selleckchem.com/products/fosfosal.html","C7H7O6P","free base","2-phosphonoxy benzoic acid","OC(=O)C1=C(O[P](O)(O)=O)C=CC=C1",0.963,2,0,3]
["S5733","Stearic acid","g5","L8000-17","in 10mM DMSO","Others","Others","Stearic acid (Octadecanoic acid, Isostearic acid, Cetylacetic acid) is a natural saturated fatty acid found in animal and vegetable fats. It could be used as a food additive and used in soaps, cosmetics and detergents.",284.48,"57-11-4",{"v":57,"d":"57.00"},200.37,{"v":-1,"d":"-1.00"},-3.52,"https://www.selleckchem.com/products/stearic-acid.html","C18H36O2","free base","Octadecanoic acid, Isostearic acid, Cetylacetic acid","CCCCCCCCCCCCCCCCCC(O)=O",7.305,1,0,16]
["S5735","Midodrine","h5","L8000-17","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Midodrine belongs to the class of medications known as vasopressors. It is an adrenergic alpha-1 agonist.",254.28,"42794-76-3",{"v":51,"d":"51.00"},200.57,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/midodrine.html","C12H18N2O4","Free Base","N/A","COC1=CC=C(OC)C(=C1)C(O)CNC(=O)CN",-0.548,3,3,6]
["S5737","Diclofenac Epolamine","a6","L8000-17","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Diclofenac Epolamine (DHEP, DIEP, diclofenac hydroxyethylpyrrolidine) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.",411.32,"119623-66-4",{"v":82,"d":"82.00"},199.36,{"v":82,"d":"82.00"},199.36,"http://www.selleckchem.com/products/diclofenac-epolamine.html","C20H24Cl2N2O3","Epolamine","DHEP, DIEP, diclofenac hydroxyethylpyrrolidine","OCCN1CCCC1.OC(=O)CC2=C(NC3=C(Cl)C=CC=C3Cl)C=CC=C2",{"v":1.58,"d":"1.580"},1,2,6]
["S5740","Palonosetron","b6","L8000-17","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Palonosetron (RS25259, RS 25259 197) is a 5-HT3 antagonist with Ki value of 0.17 nM. It is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).",296.41,"135729-61-2",{"v":59,"d":"59.00"},199.05,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/palonosetron.html","C19H24N2O","Free Base","RS25259, RS 25259 197","O=C1N(CC2CCCC3=C2C1=CC=C3)C4CN5CCC4CC5",2.745,1,0,1]
["S5749","Chlorpromazine","c6","L8000-17","in 10mM DMSO","5-HT Receptor,Dopamine Receptor,Potassium Channel,Sodium Channel","Neuronal Signaling","Chlorpromazine (CPZ) is a low-potency typical antipsychotic agent that is used to treat psychotic disorders such as schizophrenia. Chlorpromazine (CPZ) inhibits 5-HT(2A) receptor and dopamine D2 in vitro. Chlorpromazine (CPZ) also inhibits sodium channel and blocks HERG potassium channels with IC50 of 21.6 μM.",318.86,"50-53-3",{"v":64,"d":"64.00"},200.72,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/chlorpromazine.html","C17H19ClN2S","Free Base","CPZ","CN(C)CCCN1C2=C(SC3=C1C=C(Cl)C=C3)C=CC=C2",4.739,0,0,4]
["S5754","Baricitinib phosphate","d6","L8000-17","in 10mM DMSO","COVID-19,JAK","JAK/STAT","Baricitinib phosphate (INCB-028050, LY-3009104) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Baricitinib is found to reduce or interrupt the passage of the virus into target cells and is used in the treatment research for COVID-19.",469.41,"1187595-84-1",{"v":94,"d":"94.00"},200.25,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/baricitinib-phosphate.html","C16H20N7O6PS","phosphate","INCB-028050 phosphate, LY-3009104 phosphate","CC[S](=O)(=O)N1CC(CC#N)(C1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4.O[P](O)(O)=O",-0.108,5,1,5]
["S5761","Citric acid","e6","L8000-17","in 10mM DMSO","Others","Others","Citric acid is a weak organic acid that occurs naturally in citrus fruits. It is an intermediate in the citric acid cycle.",192.12,"77-92-9",{"v":38,"d":"38.00"},197.79,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/citric-acid.html","C6H8O7","Free Base","N/A","OC(=O)CC(O)(CC(O)=O)C(O)=O",-1.319,3,0,5]
["S5763","D-Mannose","f6","L8000-17","in 10mM DMSO","Others","Others","D-mannose is a naturally occurring simple sugar that may help your body cleanse the urinary tract and maintain a healthy bladder lining.",180.16,"3458-28-4",{"v":36,"d":"36.00"},199.82,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/d-mannose.html","C6H12O6","Free Base","N/A","OCC1OC(O)C(O)C(O)C1O",-2.514,1,4,1]
["S5767","Aliskiren","g6","L8000-17","in 10mM DMSO","RAAS","Metabolism","Aliskiren(CGP 60536) is a renin inhibitor with antihypertensive activity.",551.76,"173334-57-1",{"v":100,"d":"100.00"},181.24,{"v":6,"d":"6.00"},10.87,"http://www.selleckchem.com/products/aliskiren.html","C30H53N3O6","Free Base","CGP 60536","COCCCOC1=C(OC)C=CC(=C1)CC(CC(N)C(O)CC(C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C",3.327,5,4,19]
["S5780","Prazosin","h6","L8000-17","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Prazosin is an α1-blocker that acts as an inverse agonist at alpha-1 adrenergic receptors. It is used to treat hypertension.",{"v":383.4,"d":"383.40"},"19216-56-9",{"v":77,"d":"77.00"},200.83,{"v":1,"d":"1.00"},2.61,"http://www.selleckchem.com/products/prazosin.html","C19H21N5O4","Free Base","N/A","COC1=CC2=NC(=NC(=C2C=C1OC)N)N3CCN(CC3)C(=O)C4=CC=CO4",2.107,6,1,4]
["S5781","Raloxifene","a7","L8000-17","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Raloxifene (Keoxifene, Pharoxifene, LY-139481, LY-156758, CCRIS-7129) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women.",473.58,"84449-90-1",{"v":95,"d":"95.00"},{"v":200.6,"d":"200.60"},{"v":1,"d":"1.00"},2.11,"http://www.selleckchem.com/products/raloxifene.html","C28H27NO4S","Free Base","Keoxifene, Pharoxifene, LY-139481, LY-156758, CCRIS-7129","OC1=CC=C(C=C1)C2=C(C(=O)C3=CC=C(OCCN4CCCCC4)C=C3)C5=C(S2)C=C(O)C=C5",6.461,2,2,7]
["S5787","Dronedarone","b7","L8000-17","in 10mM DMSO","Adrenergic Receptor","Transmembrane Transporters","Dronedarone (SR33589) is a derivative of amiodarone which is classified as a Class III antiarrhythmic agent. It shows rate-dependent inhibition of the rapid Na+ current, inhibits α and β-adrenergic receptors like Class II agents, exhibits blockade of K+ outward currents as the main mechanism of action of Class III, and effectively block slow Ca2+ inward currents (Class IV).",556.76,"141626-36-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/dronedarone.html","C31H44N2O5S","Free Base","SR33589","CCCCN(CCCC)CCCOC1=CC=C(C=C1)C(=O)C2=C(CCCC)OC3=C2C=C(N[S](C)(=O)=O)C=C3",7.015,5,1,18]
["S5795","Rasagiline","c7","L8000-17","in 10mM DMSO","MAO","Metabolism","Rasagiline (TVP-1012) is a novel selective and irreversible MAO-B propargylamine inhibitor with in vitro IC50s of 4.43 nM and 412 nM for MAO-B and MAO-A, respectively.",171.24,"136236-51-6",{"v":34,"d":"34.00"},198.55,{"v":4,"d":"4.00"},23.36,"http://www.selleckchem.com/products/rasagiline.html","C12H13N","Free Base","TVP-1012","C#CCNC1CCC2=C1C=CC=C2",3.119,0,1,2]
["S5802","Alprenolol hydrochloride","d7","L8000-17","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Alprenolol hydrochloride is the hydrochloride salt form of alprenolol, which is an beta adrenergic receptorantagonist and is used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.",285.81,"13707-88-5",{"v":57,"d":"57.00"},199.43,{"v":57,"d":"57.00"},199.43,"http://www.selleckchem.com/products/alprenolol-hydrochloride.html","C15H24ClNO2","Hydrochloride","N/A","Cl.CC(C)NCC(O)COC1=CC=CC=C1CC=C",3.021,1,2,8]
["S5808","Relugolix","e7","L8000-17","in 10mM DMSO","GNRH Receptor","Endocrinology & Hormones","Relugolix (RVT-601, TAK-385) is a selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with IC50 of 0.33 nM and 0.32 nM for human GnRHR and monkey GnRHR, respectively.",623.63,"737789-87-6",{"v":61,"d":"61.00"},97.81,"<1","N/A","http://www.selleckchem.com/products/relugolix.html","C29H27F2N7O5S","Free Base","RVT-601, TAK-385","CONC(=O)NC1=CC=C(C=C1)C2=C(CN(C)C)C3=C(S2)N(CC4=C(F)C=CC=C4F)C(=O)N(C3=O)C5=NN=C(OC)C=C5",4.623,7,2,9]
["S5812","Choline Fenofibrate","f7","L8000-17","in 10mM DMSO","PPAR","Metabolism","Choline fenofibrate(ABT-335) is a newly developed choline salt of fenofibric acid, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity that acts as an PPARα agonist.",421.91,"856676-23-8",{"v":5,"d":"5.00"},11.85,{"v":9,"d":"9.00"},21.33,"http://www.selleckchem.com/products/choline-fenofibrate.html","C22H28ClNO5","Free Base","ABT-335","CC(C)(OC1=CC=C(C=C1)C(=O)C2=CC=C(Cl)C=C2)C([O-])=O.C[N+](C)(C)CCO",1.111,2,1,7]
["S5816","Pyrvinium","g7","L8000-17","in 10mM DMSO","Parasite","Microbiology","Pyrvinium is an anthelmintic effective for pinworms.",1151.39,"3546-41-6",{"v":22,"d":"22.00"},19.11,"<1","N/A","http://www.selleckchem.com/products/pyrvinium.html","C75H70N6O6","Free Base","N/A","CN(C)C1=CC2=CC=C(/C=C/C3=C(C)[N](C(=C3)C)C4=CC=CC=C4)[N+](=C2C=C1)C.CN(C)C5=CC6=CC=C(/C=C/C7=C(C)[N](C(=C7)C)C8=CC=CC=C8)[N+](=C6C=C5)C.OC9=C(CC%10=C(O)C(=CC%11=C%10C=CC=C%11)C([O-])=O)C%12=C(C=CC=C%12)C=C9C([O-])=O",13.931,0,2,12]
["S5821","Linoleic acid","h7","L8000-17","in 10mM DMSO","Others","Others","Linoleic acid (9,12-octadecadienoic acid) is an essential fatty acid used in the biosynthesis of arachidonic acid and found in the lipids of cell membranes.,",280.45,"60-33-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/linoleic-acid.html","C18H32O2","Free Base","9,12-octadecadienoic acid","CCCCC/C=C\\C\\C=C/CCCCCCCC(O)=O",6.416,1,0,14]
["S5863","Metronidazole Benzoate","a8","L8000-17","in 10mM DMSO","Bacterial","Microbiology","Metronidazole Benzoate (Benzoyl metronidazole) is the benzoate ester of metronidazole, a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.",275.26,"13182-89-3",{"v":55,"d":"55.00"},199.81,{"v":1,"d":"1.00"},3.63,"http://www.selleckchem.com/products/metronidazole-benzoate.html","C13H13N3O4","Benzoate","Benzoyl metronidazole","CC1=NC=C([N]1CCOC(=O)C2=CC=CC=C2)[N+]([O-])=O",1.706,3,0,6]
["S5868","DL-Menthol","b8","L8000-17","in 10mM DMSO","Others","Others","DL-Menthol is a racemic mixture of D- and L-menthol. Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils.",156.27,"89-78-1",{"v":31,"d":"31.00"},198.37,{"v":31,"d":"31.00"},198.37,"http://www.selleck.cn/products/dl-menthol.html","C10H20O","Free Base","N/A","CC(C)C1CCC(C)CC1O",2.779,0,1,1]
["S5871","Trans-Tranilast","c8","L8000-17","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Trans-Tranilast is an antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.",327.33,"70806-55-2",{"v":65,"d":"65.00"},198.58,{"v":1,"d":"1.00"},3.06,"https://www.selleckchem.com/products/trans-tranilast.html","C18H17NO5","Free Base","N/A","COC1=C(OC)C=C(\\C=C\\C(=O)NC2=C(C=CC=C2)C(O)=O)C=C1",2.679,4,1,6]
["S5872","Estradiol dipropionate","d8","L8000-17","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estradiol dipropionate (17-Beta-Estradiol-3,17-Dipropionate) is a semisynthetic, steroidal estrogen which has been used in hormone therapy for menopausal symptoms and low estrogen levels in women and in the treatment of gynecological disorders.",384.51,"113-38-2",{"v":21,"d":"21.00"},54.61,{"v":1,"d":"1.00"},{"v":2.6,"d":"2.60"},"https://www.selleckchem.com/products/estradiol-dipropionate.html","C24H32O4","Free Base","17-Beta-Estradiol-3,17-Dipropionate","CCC(=O)OC1CCC2C3CCC4=C(C=CC(=C4)OC(=O)CC)C3CCC12C",{"v":5.56,"d":"5.560"},4,0,6]
["S5873","Scopolamine HBr trihydrate","e8","L8000-17","in 10mM DMSO","AChR","Neuronal Signaling","Scopolamine HBr is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55.3 nM.",438.31,"6533-68-2",{"v":88,"d":"88.00"},200.77,{"v":88,"d":"88.00"},200.77,"https://www.selleckchem.com/products/scopolamine-hbr-trihydrate.html","C17H28BrNO7","HBr trihydrate","N/A","O.O.O.Br.CN1C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",0.693,3,1,5]
["S5901","Canagliflozin hemihydrate","f8","L8000-17","in 10mM DMSO","SGLT","GPCR & G Protein","Canagliflozin hemihydrate is the hemihydrate form of canagliflozin, which is a SGLT2 inhibitor with IC50 of 2.2 nM for hSGLT2 in a cell-free assay, exhibits 413-fold selectivity over hSGLT1.",907.05,"928672-86-0",{"v":100,"d":"100.00"},110.25,"<1","N/A","http://www.selleckchem.com/products/canagliflozin-hemihydrate.html","C48H52F2O11S2","hemihydrate","N/A","O.CC1=C(CC2=CC=C(S2)C3=CC=C(F)C=C3)C=C(C=C1)C4OC(CO)C(O)C(O)C4O.CC5=C(CC6=CC=C(S6)C7=CC=C(F)C=C7)C=C(C=C5)C8OC(CO)C(O)C(O)C8O",6.686,2,8,10]
["S5927","Proguanil","g8","L8000-17","in 10mM DMSO","Anti-infection,DHFR","Microbiology","Proguanil (chlorguanide, chloroguanide) is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.",253.73,"500-92-5",{"v":51,"d":"51.00"},{"v":201,"d":"201.00"},{"v":1,"d":"1.00"},3.94,"http://www.selleckchem.com/products/proguanil.html","C11H16ClN5","Free Base","chlorguanide, chloroguanide","CC(C)NC(=N)NC(=N)NC1=CC=C(Cl)C=C1",2.226,0,3,6]
["S5939","Bendamustine (SDX105)","h8","L8000-17","in 10mM DMSO","Others","Others","Bendamustine (SDX105) is a nitrogen mustard drug used in the treatment of chronic lymphocytic leukemia (CLL), multiple myeloma, and non-Hodgkin's lymphoma.",358.26,"16506-27-7",{"v":72,"d":"72.00"},200.97,"<1","N/A","http://www.selleck.cn/products/bendamustine.html","C16H21Cl2N3O2","Free Base","SDX105","C[N]1C(=NC2=C1C=CC(=C2)N(CCCl)CCCl)CCCC(O)=O",3.606,2,0,9]
["S5950","Fingolimod","a9","L8000-17","in 10mM DMSO","S1P Receptor","Neuronal Signaling","Fingolimod (FTY-720A, FTY-720) is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis.",307.47,"162359-55-9",{"v":13,"d":"13.00"},42.28,{"v":1,"d":"1.00"},3.25,"https://www.selleckchem.com/products/fingolimod.html","C19H33NO2","Free Base","FTY-720A, FTY-720","CCCCCCCCC1=CC=C(CCC(N)(CO)CO)C=C1",4.198,0,3,12]
["S6003","Ataluren (PTC124)","b9","L8000-17","in 10mM DMSO","CFTR","Transmembrane Transporters","Ataluren (PTC124) selectively induces ribosomal read-through of premature but not normal termination codons, with EC50 of 0.1 μM in HEK293 cells, may provide treatment for genetic disorders caused by nonsense mutations (e.g. CF caused by CFTR nonsense mutation). Phase 3.",284.24,"775304-57-9",{"v":57,"d":"57.00"},200.53,"<1","N/A","http://selleckchem.com/products/PTC124.html","C15H9FN2O3","free base","N/A","OC(=O)C1=CC=CC(=C1)C2=NOC(=N2)C3=CC=CC=C3F",{"v":2.98,"d":"2.980"},4,0,3]
["S6055","(S)-(−)-Limonene","c9","L8000-17","in 10mM DMSO","Others","Others","(S)-(−)-Limonene, a fragrance monoterpene mainly found in citrus peel oil, is also naturally occurs in the essential oils of herbs, tea tree oil, and turpentine oil.,",136.23,"5989-54-8","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleck.cn/products/limonene.html","C10H16","free base","N/A","CC(=C)C1CCC(=CC1)C",3.502,0,0,1]
["S6058","β-Caryophyllene","d9","L8000-17","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","β-Caryophyllene is a natural bicyclic sesquiterpene that is a constituent of many essential oils. It acts as a non-steroidal anti-inflammatory drug, a fragrance and a metabolite.",204.35,"87-44-5","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleck.cn/products/caryophyllene.html","C15H24","free base","N/A","CC/1=C\\CCC(=C)C2CC(C)(C)C2CC1",4.753,0,0,0]
["S6068","Doxycycline monohydrate","e9","L8000-17","in 10mM DMSO","Antibiotics","Microbiology","Doxycycline is a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity.",462.45,"17086-28-1",{"v":47,"d":"47.00"},101.63,"N/A","N/A","http://www.selleck.cn/products/doxycycline-monohydrate.html","C22H26N2O9","monohydrate","N/A","O.CC1C2C(O)C3C(N(C)C)C(=C(C(N)=O)C(=O)C3(O)C(=C2C(=O)C4=C1C=CC=C4O)O)O",-0.959,3,5,2]
["S6073","Diclofenac acid","f9","L8000-17","in 10mM DMSO","COX,Immunology & Inflammation related","Immunology & Inflammation","Diclofenac acid is a nonsteroidal anti-inflammatory drug that has analgesic, anti-inflammatory, and antipyretic properties, and has been shown to be effective in treating a variety of acute and chronic pain and inflammatory conditions. It inhibits cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) with relative equipotency.",296.15,"15307-86-5",{"v":59,"d":"59.00"},199.22,"N/A","N/A","http://www.selleck.cn/products/diclofenac-acid.html","C14H11Cl2NO2","free base","N/A","OC(=O)CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1",4.373,1,1,4]
["S6115","Pyridoxal 5′-phosphate hydrate","g9","L8000-17","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Pyridoxal 5′-phosphate (pyridoxal phosphate, Vitamin B6 phosphate, PAL-P, PLP), a vitamin B6 phosphate, is a coenzyme in a variety of enzymatic reactions. Pyridoxal 5′-phosphate at concentrations < 0.5 mM inhibits of polymerization deoxynucleoside triphosphate catalysed by variety of DNA polymerases isolated from type C RNA tumor viruses. The combination of Pyridoxal 5′-phosphate and NEIL2 will make NEIL2 completely lose its ability to bind damaged DNA.",247.14,"853645-22-4",{"v":10,"d":"10.00"},40.46,"N/A","N/A","http://www.selleck.cn/products/pyridoxal-5-phosphate-hydrate.html","C8H10NO6P.xH2O","hydrate","pyridoxal phosphate, Vitamin B6 phosphate, PAL-P, PLP","CC1=NC=C(CO[P](O)(O)=O)C(=C1O)C=O",0.537,3,1,4]
["S6118","Terpinen-4-ol","h9","L8000-17","in 10mM DMSO","Fungal","Microbiology","Terpinen-4-ol, a naturally occurring monoterpene, is the main bioactive component of tea-tree oil and has been shown to have many biological activities such as antifungal properties.,",154.25,"562-74-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleck.cn/products/terpinen-4-ol.html","C10H18O","free base","N/A","CC(C)C1(O)CCC(=CC1)C",{"v":2.55,"d":"2.550"},0,0,1]
["S6136","(±)-α-Bisabolol","a10","L8000-17","in 10mM DMSO","Anti-infection,Immunology & Inflammation related","Immunology & Inflammation","α-bisabolol is a small, plant-derived, oily sesquiterpene alcohol with some anti-inflammatory and even anti-microbial properties.",222.37,"515-69-5","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleck.cn/products/bisabolol.html","C15H26O","free base","N/A","CC(C)=CCCC(C)(O)C1CCC(=CC1)C",4.309,0,0,4]
["S6288","Chlorhexidine diacetate","b10","L8000-17","in 10mM DMSO","Anti-infection","Microbiology","Chlorhexidine diacetate (Hibitane diacetate) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.",625.55,"56-95-1",125.11,{"v":200,"d":"200.00"},"N/A","N/A","http://www.selleck.cn/products/chlorhexidine-diacetate.html","C26H38Cl2N10O4","diacetate","Hibitane diacetate","CC(O)=O.CC(O)=O.ClC1=CC=C(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC2=CC=C(Cl)C=C2)C=C1",3.964,2,6,17]
["S6400","Glucosamine","c10","L8000-17","in 10mM DMSO","HIF","Angiogenesis","Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine（GS） treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites.",179.17,"3416-24-8",{"v":23,"d":"23.00"},128.37,{"v":36,"d":"36.00"},200.93,"http://www.selleck.cn/products/glucosamine.html","C6H13NO5","Free Base","2-amino-2-deoxy-D-glucose","NC(C=O)C(O)C(O)C(O)CO",-3.081,1,5,5]
["S6402","2-Aminoethanethiol","d10","L8000-17","in 10mM DMSO","Others","Others","2-Aminoethanethiol (cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Thioethanolamine, Mercaptamine) is a radiation-protective agent that oxidizes in air to form cystamine.",77.15,"60-23-1",{"v":15,"d":"15.00"},194.43,{"v":15,"d":"15.00"},194.43,"http://www.selleck.cn/products/2-aminoethanethiol.html","C2H7NS","Free Base","cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Decarboxycysteine, Thioethanolamine, Mercaptamine","NCCS",-0.216,0,1,1]
["S6404","Salicylamide","e10","L8000-17","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Salicylamide (o-hydroxybenzamide) is a non-prescription drug with analgesic and antipyretic properties.",137.14,"65-45-2",{"v":27,"d":"27.00"},196.88,"˂1","N/A","http://www.selleck.cn/products/salicylamide.html","C7H7NO2","Free Base","o-hydroxybenzamide","NC(=O)C1=C(O)C=CC=C1",{"v":0.59,"d":"0.590"},1,2,1]
["S6407","Tulobuterol hydrochloride","f10","L8000-17","in 10mM DMSO","Androgen Receptor","Neuronal Signaling","Tulobuterol is a long-acting β2-adrenergic receptor agonist that has bronchodilatory, anti-inflammatory, and antiviral activities.",264.19,"56776-01-3",{"v":53,"d":"53.00"},200.61,{"v":53,"d":"53.00"},200.61,"http://www.selleck.cn/products/tulobuterol-hydrochloride.html","C12H19Cl2NO","hydrochloride","N/A","Cl.CC(C)(C)NCC(O)C1=C(Cl)C=CC=C1",2.834,0,2,4]
["S6409","Zucapsaicin","g10","L8000-17","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Zucapsaicin, the cis-isomer of capsaicin, is a topical analgesic used to treat osteoarthritis of the knee and other neuropathic pain. It is also a TRPV-1 modulator.",305.41,"25775-90-0",{"v":61,"d":"61.00"},199.73,"<1","N/A","http://www.selleck.cn/products/zucapsaicin.html","C18H27NO3","Free Base","N/A","COC1=C(O)C=CC(=C1)CNC(=O)CCCC\\C=C/C(C)C",{"v":3.91,"d":"3.910"},2,2,9]
["S6410","Clemizole","h10","L8000-17","in 10mM DMSO","Dopamine Receptor,TRP Channel","Neuronal Signaling","Clemizole, a first-generation histamine receptor (H1) antagonist, is a potent inhibitor of behavioural and electrographic seizure activity. It has a potential therapeutic effect on hepatitis C infection and also potently inhibits TRPC5 ion channels.",325.84,"442-52-4",{"v":65,"d":"65.00"},199.48,{"v":-1,"d":"-1.00"},"N/A","http://www.selleck.cn/products/clemizole.html","C19H20ClN3","Free Base","N/A","ClC1=CC=C(C[N]2C(=NC3=C2C=CC=C3)CN4CCCC4)C=C1",4.527,1,0,4]
["S6411","Nimorazole","a11","L8000-17","in 10mM DMSO","Bacterial","Microbiology","Nimorazole is a water soluble, 5-nitroimidazole compound with antibacterial and potential radiosensitizing activity.",226.23,"6506-37-2",{"v":45,"d":"45.00"},198.91,{"v":-1,"d":"-1.00"},"N/A","http://www.selleck.cn/products/nimorazole.html","C9H14N4O3","Free Base","N/A","[O-][N+](=O)C1=CN=C[N]1CCN2CCOCC2",-0.232,2,0,4]
["S6441","Riboflavin Tetrabutyrate","b11","L8000-17","in 10mM DMSO","Others","Others","Riboflavin tetrabutyrate is a lipophilic flavin derivative with antioxidative and lipid peroxide-removing activity.",656.72,"752-56-7",{"v":100,"d":"100.00"},152.27,"<1","N/A","http://www.selleck.cn/products/riboflavin-tetrabutyrate.html","C33H44N4O10","Tetrabutyrate","N/A","CCCC(=O)OCC(OC(=O)CCC)C(OC(=O)CCC)C(CN1C2=C(C=C(C)C(=C2)C)N=C3C(=O)NC(=O)N=C13)OC(=O)CCC",5.754,12,1,21]
["S6453","Bicyclol","c11","L8000-17","in 10mM DMSO","HBV","Microbiology","Bicyclol (SY-801) is a drug that can improve liver function and inhibit HBV replication.",390.34,"118159-48-1",{"v":78,"d":"78.00"},199.83,"<1","N/A","http://www.selleck.cn/products/bicyclol.html","C19H18O9","Free Base","SY-801","COC(=O)C1=CC(=C2OCOC2=C1C3=C4OCOC4=C(OC)C=C3CO)OC",2.102,8,1,6]
["S6455","Clebopride malate","d11","L8000-17","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Clebopride is a dopamine antagonist drug and is used to treat functional gastrointestinal disorder such as nausea or vomiting.",507.96,"57645-91-7",{"v":100,"d":"100.00"},196.87,{"v":33,"d":"33.00"},64.97,"http://www.selleck.cn/products/clebopride.html","C24H30ClN3O7","malate","N/A","COC1=C(C=C(Cl)C(=C1)N)C(=O)NC2CC[NH+](CC2)CC3=CC=CC=C3.OC(CC(O)=O)C([O-])=O",-1.413,3,3,8]
["S6456","Glycyrrhetinic acid","e11","L8000-17","in 10mM DMSO","Others","Others","Glycyrrhetinic acid is a triterpenoid aglycone component of the natural product glycyrrhizinic acid and possesses remarkable anti-proliferative and apoptosis-inducing activity in various cancer cell lines.",470.68,"1449-05-4",{"v":94,"d":"94.00"},199.71,"<1","N/A","http://www.selleck.cn/products/glycyrrhetinic-acid.html","C30H46O4","Free Base","N/A","CC1(C)C(O)CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O",5.656,2,1,1]
["S6457","Flurbiprofen Axetil","f11","L8000-17","in 10mM DMSO","COX","Immunology & Inflammation","Flurbiprofen Axetil is one of the commonly used nonsteroidal anti-inflammatory drugs (NSAIDs) that nonselectively inhibits cyclooxygenase.",330.35,"91503-79-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleck.cn/products/flurbiprofen-axetil.html","C19H19FO4","Free Base","N/A","CC(OC(C)=O)OC(=O)C(C)C1=CC=C(C(=C1)F)C2=CC=CC=C2",3.906,4,0,7]
["S6459","Nifurtimox","g11","L8000-17","in 10mM DMSO","Anti-infection","Microbiology","Nifurtimox (BAY-2502) is an antiprotozoal agent.",287.29,"23256-30-6",{"v":57,"d":"57.00"},198.41,"<1","N/A","http://www.selleck.cn/products/nifurtimox.html","C10H13N3O5S","Free Base","BAY-2502","CC1C[S](=O)(=O)CCN1\\N=C\\C2=CC=C(O2)[N+]([O-])=O",0.772,4,0,3]
["S6476","Eicosapentaenoic Acid","h11","L8000-17","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Eicosapentaenoic acid (EPA) is an omega-3 polyunsaturated fatty acid with antiinflammatory properties, and is present in fish and fish oils, including salmon, cod, and krill oils.",302.45,"10417-94-4",{"v":60,"d":"60.00"},198.38,"<1","N/A","http://www.selleck.cn/products/eicosapentaenoic-acid.html","C20H30O2","Free Base","N/A","CC/C=C\\C\\C=C/C/C=C\\C\\C=C/C/C=C\\CCCC(O)=O",5.994,1,0,13]
["S6484","uridine triacetate","a2","L8000-18","in 10mM DMSO","Others","Others","Uridine triacetate (Vistonuridine, PN401) is an orally active prodrug of the naturally occurring nucleoside uridine. It is used for the treatment of hereditary orotic aciduria (Xuriden), or for the emergency treatment of fluorouracil or capecitabine overdose or toxicity.",370.31,"4105-38-8",{"v":74,"d":"74.00"},199.83,{"v":7,"d":"7.00"},{"v":18.9,"d":"18.90"},"http://www.selleck.cn/products/uridine-triacetate.html","C15H18N2O9","triacetate","Vistonuridine, PN401","CC(=O)OCC1OC(C(OC(C)=O)C1OC(C)=O)N2C=CC(=O)NC2=O",-1.314,9,1,8]
["S6588","Methylprednisolone hemisuccinate","b2","L8000-18","in 10mM DMSO","Others","Others","Methylprednisolone sodium succinate is a glucocorticoid used to treat a variety health issues including severe allergic reactions, asthma, autoimmune diseases, blood disorders, gastrointestinal diseases and endocrine disorders.",474.54,"2921-57-5",{"v":95,"d":"95.00"},200.19,"<1","N/A","https://www.selleckchem.com/products/methylprednisolone-hemisuccinate-s6588.html","C26H34O8","free base","N/A","CC1CC2C3CCC(O)(C(=O)COC(=O)CCC(O)=O)C3(C)CC(O)C2C4(C)C=CC(=O)C=C14",1.736,5,1,7]
["S6590","Hydrocortisone butyrate","c2","L8000-18","in 10mM DMSO","Others","Others","Hydrocortisone butyrate is a potent topical corticosteroid that can be used to treat a range of inflammatory skin conditions.",432.55,"13609-67-1",{"v":87,"d":"87.00"},201.13,"<1","N/A","http://www.selleck.cn/products/hydrocortisone-butyrate.html","C25H36O6","free base","N/A","CCCC(=O)OC1(CCC2C3CCC4=CC(=O)CCC4(C)C3C(O)CC12C)C(=O)CO",2.785,4,2,6]
["S6601","(±)-Equol","d2","L8000-18","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","(±)-Equol, an isoflavandiol estrogen, is a metabolite of the soy isoflavones, daidzin and daidzein.",242.27,"94105-90-5",{"v":48,"d":"48.00"},198.13,"<1","N/A","https://www.selleckchem.com/products/equol-1.html","C15H14O3","free base","N/A","OC1=CC=C(C=C1)C2COC3=C(C2)C=CC(=C3)O",3.211,1,2,1]
["S6614","Fursultiamine","e2","L8000-18","in 10mM DMSO","Vitamin","Metabolism","Fursultiamine (Thiamine tetrahydrofurfuryl disulfide) is a nutritional supplement and vitamin B1 derivative, with potential antineoplastic activity.",398.54,"804-30-8",{"v":80,"d":"80.00"},200.73,{"v":3,"d":"3.00"},7.53,"http://www.selleck.cn/products/fursultiamine.html","C17H26N4O3S2","free base","Thiamine tetrahydrofurfuryl disulfide","CC1=NC=C(CN(C=O)/C(C)=C(CCO)/SSCC2CCCO2)C(=N1)N",0.221,4,2,9]
["S7007","Binimetinib (MEK162)","f2","L8000-18","in 10mM DMSO","Apoptosis related,Autophagy,MEK","MAPK","Binimetinib (MEK162, ARRY-162, ARRY-438162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM in a cell-free assay. Binimetinib induces G1 cell cycle arrest and apoptosis in human NSCLC cell lines and induces autophagy. Phase 3.",441.23,"606143-89-9",{"v":88,"d":"88.00"},199.44,"<1","N/A","http://selleckchem.com/products/mek162.html","C17H15BrF2N4O3","free base","ARRY-162,ARRY-438162","C[N]1C=NC2=C1C=C(C(=O)NOCCO)C(=C2F)NC3=C(F)C=C(Br)C=C3",2.775,3,3,6]
["S7025","Embelin","g2","L8000-18","in 10mM DMSO","Antineoplastic and Immunosuppressive Antibiotics,IAP","Apoptosis","Embelin (Embelic Acid, NSC 91874), a quinone isolated from the Japanese Ardisia herb, is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 μM in a cell-free assay.",294.39,"550-24-3",{"v":59,"d":"59.00"},200.41,"<1","N/A","http://selleckchem.com/products/embelin.html","C17H26O4","free base","Embelic Acid, NSC 91874","CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O",{"v":4.62,"d":"4.620"},2,2,10]
["S7028","Duvelisib (IPI-145)","h2","L8000-18","in 10mM DMSO","PI3K","Angiogenesis","Duvelisib (IPI-145, INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM in cell-free assays, highly selective for PI3K δ/γ than other protein kinases. Phase 3.",416.86,"1201438-56-3",{"v":83,"d":"83.00"},199.11,"<1","N/A","http://selleckchem.com/products/ipi-145-ink1197.html","C22H17ClN6O","free base","INK1197","CC(NC1=NC=NC2=C1N=C[NH]2)C3=CC4=CC=CC(=C4C(=O)N3C5=CC=CC=C5)Cl",3.648,4,2,4]
["S7059","Tezacaftor (VX-661)","a3","L8000-18","in 10mM DMSO","CFTR","Transmembrane Transporters","Tezacaftor (VX-661) is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. Phase 2.",{"v":520.5,"d":"520.50"},"1152311-62-0",{"v":100,"d":"100.00"},192.12,"<1","N/A","http://selleckchem.com/products/vx-661.html","C26H27F3N2O6","free base","N/A","CC(C)(CO)C1=CC2=CC(=C(F)C=C2[N]1CC(O)CO)NC(=O)C3(CC3)C4=CC=C5OC(F)(F)OC5=C4",5.215,3,4,8]
["S7077","Cilengitide trifluoroacetate","b3","L8000-18","in 10mM DMSO","Integrin","Cytoskeletal Signaling","Cilengitide (EMD 121974, NSC 707544) is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.",702.68,"199807-35-7",{"v":100,"d":"100.00"},142.31,{"v":8,"d":"8.00"},11.38,"http://selleckchem.com/products/cilengitide-emd-121974-nsc-707544.html","C29H41F3N8O9","Trifluoroacetat","EMD 121974, NSC 707544","CC(C)C1N(C)C(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CCCNC(N)=N)NC1=O.OC(=O)C(F)(F)F",-0.565,7,6,11]
["S7083","Ceritinib (LDK378)","c3","L8000-18","in 10mM DMSO","ALK,FLT3,IGF-1R,Serine/threonin kinase","Protein Tyrosine Kinase","Ceritinib (LDK378) is a potent inhibitor against ALK with IC50 of 0.2 nM in cell-free assays. Ceritinib (LDK378) also inhibits IGF-1R, InsR, STK22D and FLT3 with IC50 of 8 nM, 7 nM, 23 nM and 60 nM, respectively. Phase 3.",558.14,"1032900-25-6",{"v":20,"d":"20.00"},35.83,"<1","N/A","http://selleckchem.com/products/ldk378.html","C28H36ClN5O3S","free base","N/A","CC(C)OC1=C(NC2=NC(=C(Cl)C=N2)NC3=C(C=CC=C3)[S](=O)(=O)C(C)C)C=C(C)C(=C1)C4CCNCC4",6.479,5,3,9]
["S7091","Zotarolimus (ABT-578)","d3","L8000-18","in 10mM DMSO","FKBP,mTOR","PI3K/Akt/mTOR","Zotarolimus (ABT-578,A 179578) is an analogue of rapamycin, and inhibits FKBP-12 binding with IC50 of 2.8 nM.",966.21,"221877-54-9",{"v":100,"d":"100.00"},{"v":103.5,"d":"103.50"},"<1","N/A","http://selleckchem.com/products/zotarolimus-abt-578.html","C52H79N5O12","free base","A 179578","COC1CC(CCC1[N]2C=NN=N2)CC(C)C3CC(=O)C(C)/C=C(C)/C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC4CCC(C)C(O)(O4)C(=O)C(=O)N5CCCCC5C(=O)O3)OC",5.793,13,1,7]
["S7156","Marimastat (BB-2516)","e3","L8000-18","in 10mM DMSO","MMP","Proteases","Marimastat (BB-2516, TA2516) is a broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 with IC50 of 3 nM, 5 nM, 6 nM, 9 nM and 13 nM, respectively. Phase 3.",331.41,"154039-60-8",{"v":54,"d":"54.00"},162.94,"<1","N/A","http://selleckchem.com/products/marimastat.html","C15H29N3O5","free base","TA2516","CNC(=O)C(NC(=O)C(CC(C)C)C(O)C(=O)NO)C(C)(C)C",0.239,3,4,8]
["S7158","Abemaciclib mesylate (LY2835219)","f3","L8000-18","in 10mM DMSO","CDK","Cell Cycle","Abemaciclib (LY2835219) is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively. Phase 3.",{"v":602.7,"d":"602.70"},"1231930-82-7",{"v":83,"d":"83.00"},137.71,{"v":100,"d":"100.00"},165.92,"http://selleckchem.com/products/ly2835219.html","C27H32F2N8.CH4O3S","mesylate","N/A","CCN1CCN(CC1)CC2=CC=C(NC3=NC(=C(F)C=N3)C4=CC(=C5N=C(C)[N](C(C)C)C5=C4)F)N=C2.C[S](O)(=O)=O",4.543,4,1,7]
["S7160","Glasdegib (PF-04449913)","g3","L8000-18","in 10mM DMSO","Hedgehog/Smoothened","Stem Cells & Wnt","Glasdegib (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2.",374.44,"1095173-27-5",{"v":47,"d":"47.00"},125.52,"<1","N/A","http://selleckchem.com/products/glasdegib-pf-04449913.html","C21H22N6O","Free Base","N/A","CN1CCC(CC1C2=NC3=CC=CC=C3[NH]2)NC(=O)NC4=CC=C(C=C4)C#N",2.363,2,3,3]
["S7179","Siponimod (BAF312)","h3","L8000-18","in 10mM DMSO","S1P Receptor","GPCR & G Protein","BAF312 (Siponimod) is a next-generation S1P receptor agonist, selective for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, exhibits >1000-fold selectivity over S1P2, S1P3 and S1P4 receptors. Phase 3.",{"v":516.6,"d":"516.60"},"1230487-00-9",{"v":100,"d":"100.00"},193.57,"<1","N/A","http://selleckchem.com/products/baf312-siponimod.html","C29H35F3N2O3","free base","N/A","CCC1=CC(=CC=C1CN2CC(C2)C(O)=O)\\C(C)=N\\OCC3=CC=C(C4CCCCC4)C(=C3)C(F)(F)F",3.834,3,0,10]
["S7252","Selinexor (KPT-330)","a4","L8000-18","in 10mM DMSO","CRM1","Transmembrane Transporters","Selinexor (KPT-330, ATG-010) is an orally bioavailable selective CRM1 inhibitor. Phase 2.",443.31,"1393477-72-9",{"v":88,"d":"88.00"},198.51,"<1","N/A","http://selleckchem.com/products/kpt-330.html","C17H11F6N7O","free base","ATG-010","FC(F)(F)C1=CC(=CC(=C1)C2=N[N](\\C=C/C(=O)NNC3=CN=CC=N3)C=N2)C(F)(F)F",2.345,5,2,7]
["S7280","Edoxaban tosylate Monohydrate","b4","L8000-18","in 10mM DMSO","Factor Xa","Metabolism","Edoxaban (DU-176b) is a selective factor Xa inhibitor with Ki of 0.561 nM, >10 000-fold selectivity over thrombin and FIXa, and is also an orally bioavailable anticoagulant drug.",738.27,"1229194-11-9",{"v":100,"d":"100.00"},135.45,"<1","N/A","http://selleckchem.com/products/edoxaban.html","C24H30ClN7O4S.C7H8O3S.H2O","Tosylate hydrate","DU-176b","O.CN(C)C(=O)C1CCC(NC(=O)C(=O)NC2=CC=C(Cl)C=N2)C(C1)NC(=O)C3=NC4=C(CN(C)CC4)S3.CC5=CC=C(C=C5)[S](O)(=O)=O",2.286,6,3,7]
["S7297","Osimertinib (AZD9291)","c4","L8000-18","in 10mM DMSO","EGFR","Protein Tyrosine Kinase","Osimertinib (AZD9291) is an oral, irreversible, and mutant-selective EGFR inhibitor with IC50 of 12.92, 11.44 and 493.8 nM for Exon 19 deletion EGFR, L858R/T790M EGFR, and WT EGFR in LoVo cells, respectively. Phase 3.",499.61,"1421373-65-0",{"v":99,"d":"99.00"},198.15,"<1","N/A","http://selleckchem.com/products/azd9291.html","C28H33N7O2","free base","Mereletinib","COC1=C(NC2=NC=CC(=N2)C3=C[N](C)C4=C3C=CC=C4)C=C(NC(=O)C=C)C(=C1)N(C)CCN(C)C",4.671,4,2,10]
["S7303","Rilpivirine","d4","L8000-18","in 10mM DMSO","Reverse Transcriptase","Microbiology","Rilpivirine (R278474, TMC27, DB08864) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), and used to treat HIV-1 infection.",366.42,"500287-72-9",{"v":73,"d":"73.00"},199.22,"<1","N/A","http://selleckchem.com/products/rilpivirine.html","C22H18N6","free base","R278474, TMC278, DB08864","CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N",5.409,2,2,5]
["S7397","Sorafenib (BAY 43-9006)","e4","L8000-18","in 10mM DMSO","Apoptosis related,Autophagy,Ferroptosis,FLT3,PDGFR,Raf,VEGFR","MAPK","Sorafenib (BAY 43-9006, NSC-724772) is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.",464.82,"284461-73-0",{"v":63,"d":"63.00"},135.54,"<1","N/A","http://selleckchem.com/products/sorafenib.html","C21H16ClF3N4O3","Free Base","NSC-724772,BAY 43-9006","CNC(=O)C1=CC(=CC=N1)OC2=CC=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2",4.175,4,3,6]
["S7417","Puromycin (CL13900) 2HCl","f4","L8000-18","in 10mM DMSO","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Selection Antibiotics for Transfected Cell","Microbiology","Puromycin 2HCl (CL13900) is an aminonucleoside antibiotic, which acts as a protein synthesis inhibitor.",544.43,"58-58-2",{"v":100,"d":"100.00"},183.68,{"v":100,"d":"100.00"},183.68,"http://selleckchem.com/products/Puromycin-2HCl.html","C22H29N7O5.2HCl","Dihydrochloride","N/A","Cl.Cl.COC1=CC=C(CC(N)C(=O)NC2C(O)C(OC2CO)[N]3C=NC4=C3N=CN=C4N(C)C)C=C1",0.586,6,4,8]
["S7440","Ribociclib (LEE011)","g4","L8000-18","in 10mM DMSO","CDK","Cell Cycle","Ribociclib (LEE011) is an orally available, and highly specific inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM. Phase 3.",434.54,"1211441-98-3",{"v":7,"d":"7.00"},16.11,"<1","N/A","http://selleckchem.com/products/lee011.html","C23H30N8O","free base","N/A","CN(C)C(=O)C1=CC2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2[N]1C5CCCC5",{"v":2.9,"d":"2.900"},4,2,5]
["S7470","Triapine","a5","L8000-18","in 10mM DMSO","DNA/RNA Synthesis,RNR","DNA Damage/DNA Repair","Triapine (3-AP) is a potent ribonucleotide reductase (RNR) inhibitor with broad spectrum antitumor activity by inhibiting DNA synthesis. Phase 2.",195.24,"200933-27-3",{"v":20,"d":"20.00"},102.44,"<1","N/A","http://selleckchem.com/products/triapine.html","C7H9N5S","free base","3-AP","NC(=S)N/N=C/C1=NC=CC=C1N",0.331,2,3,3]
["S7505","(S)-crizotinib","b5","L8000-18","in 10mM DMSO","MTH1,NUDIX","DNA Damage/DNA Repair","(S)-crizotinib, the (S)-enantiomer of crizotinib, is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM in a cell-free assay.",450.34,"1374356-45-2",{"v":42,"d":"42.00"},93.26,"<1","N/A","http://selleckchem.com/products/s-crizotinib.html","C21H22Cl2FN5O","free base","N/A","CC(OC1=C(N)N=CC(=C1)C2=C[N](N=C2)C3CCNCC3)C4=C(Cl)C=CC(=C4Cl)F",3.693,3,2,5]
["S7536","Lorlatinib (PF-6463922)","c5","L8000-18","in 10mM DMSO","ALK,Apoptosis related,ROS1","Protein Tyrosine Kinase","Lorlatinib (PF-6463922) is a potent, dual ALK/ROS1 inhibitor with Ki of <0.02 nM, <0.07 nM, and 0.7 nM for ROS1, ALK (WT), and ALK (L1196M), respectively. PF-06463922 induces apoptosis. Phase 1.",406.41,"1454846-35-5",{"v":81,"d":"81.00"},199.31,"<1","N/A","http://selleckchem.com/products/pf-06463922.html","C21H19FN6O2","free base","N/A","CC1OC2=C(N)N=CC(=C2)C3=C(C#N)[N](C)N=C3CN(C)C(=O)C4=C1C=C(F)C=C4",2.343,4,1,0]
["S7559","Darolutamide (ODM-201)","d5","L8000-18","in 10mM DMSO","Androgen Receptor","Endocrinology & Hormones","Darolutamide (ODM-201, BAY-1841788) is a novel androgen receptor (AR) antagonist that blocks AR nuclear translocation with Ki of 11 nM. Phase 3.",398.85,"1297538-32-9",{"v":80,"d":"80.00"},200.58,"<1","N/A","http://selleckchem.com/products/odm-201.html","C19H19ClN6O2","free base","BAY-1841788","CC(O)C1=CC(=N[NH]1)C(=O)NC(C)C[N]2C=CC(=N2)C3=CC(=C(C=C3)C#N)Cl",3.034,3,3,6]
["S7579","Ledipasvir (GS5885)","e5","L8000-18","in 10mM DMSO","COVID-19,HCV Protease","Microbiology","Ledipasvir (GS5885) is a HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection.",{"v":889,"d":"889.00"},"1256388-51-8",{"v":100,"d":"100.00"},112.49,"<1","N/A","http://selleckchem.com/products/ledipasvir-gs5885.html","C49H54F2N8O6","free base","N/A","COC(=O)NC(C(C)C)C(=O)N1C2CCC(C2)C1C3=NC4=CC=C(C=C4[NH]3)C5=CC=C6C7=CC=C(C=C7C(F)(F)C6=C5)C8=CN=C([NH]8)C9CCC%10(CC%10)N9C(=O)C(NC(=O)OC)C(C)C",7.304,8,4,12]
["S7625","Niraparib (MK-4827) tosylate","f5","L8000-18","in 10mM DMSO","Apoptosis related,PARP","DNA Damage/DNA Repair","Niraparib tosylate (MK-4827, ZEJULA) is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. Niraparib increases formation of PARP-DNA complexes resulting in DNA damage, apoptosis, and cell death.",492.59,"1038915-73-9",{"v":98,"d":"98.00"},198.95,"<1","N/A","http://selleckchem.com/products/mk-4827-niraparib-tosylate.html","C19H20N4O.C7H8O3S","4-?methylbenzen","Niraparib tosylate, MK 4827 tosylate, ZEJULA","CC1=CC=C(C=C1)[S](O)(=O)=O.NC(=O)C2=CC=CC3=C[N](N=C23)C4=CC=C(C=C4)C5CCCNC5",4.267,2,2,4]
["S7633","Lomitapide Mesylate","g5","L8000-18","in 10mM DMSO","MTP","Transmembrane Transporters","Lomitapide Mesylate(AEGR-733 Mesylate,BMS-2138 Mesylate) is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia.",789.83,"202914-84-9",{"v":100,"d":"100.00"},126.61,"<1","N/A","http://selleckchem.com/products/lomitapide-mesylate.html","C40H41F6N3O5S","Mesylate","AEGR-733 Mesylate,BMS-2138 Mesylate","C[S](O)(=O)=O.FC(F)(F)CNC(=O)C1(CCCCN2CCC(CC2)NC(=O)C3=C(C=CC=C3)C4=CC=C(C=C4)C(F)(F)F)C5=C(C=CC=C5)C6=C1C=CC=C6",7.377,2,2,12]
["S7650","Peficitinib (ASP015K)","h5","L8000-18","in 10mM DMSO","JAK","JAK/STAT","Peficitinib (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.",326.39,"944118-01-8",{"v":65,"d":"65.00"},199.15,"<1","N/A","http://selleckchem.com/products/peficitinb-asp015k-jnj-54781532.html","C18H22N4O2","free base","JNJ-54781532","NC(=O)C1=C(N[CH]2C3C[CH]4CC2C[C](O)(C4)C3)C5=C([NH]C=C5)N=C1",1.023,2,3,3]
["S7660","Obeticholic Acid","a6","L8000-18","in 10mM DMSO","Autophagy,FXR","Metabolism","Obeticholic Acid (INT-747, 6-ECDCA, 6-Ethylchenodeoxycholic acid) is a potent and selective farnesoid X receptor (FXR) agonist with EC50 of 99 nM. Obeticholic Acid inhibits autophagy. Phase 3.",420.63,"459789-99-2",{"v":84,"d":"84.00"},{"v":199.7,"d":"199.70"},"<1","N/A","http://selleckchem.com/products/obeticholic-acid.html","C26H44O4","free base","INT-747, 6-ECDCA, 6-Ethylchenodeoxycholic acid","CCC1C(O)C2C3CCC(C(C)CCC(O)=O)C3(C)CCC2C4(C)CCC(O)CC14",{"v":4.79,"d":"4.790"},1,2,5]
["S7663","Ruboxistaurin (LY333531) HCl","b6","L8000-18","in 10mM DMSO","PKC","TGF-beta/Smad","Ruboxistaurin (LY333531) HCl is a β-specific protein kinase C inhibitor. It competitively and reversibly inhibits PKCβ1 and PKCβ2 with IC50 values of 4.7 and 5.9 nM respectively.",505.01,"169939-93-9",{"v":50,"d":"50.00"},99.01,"<1","N/A","http://selleckchem.com/products/ly333531.html","C28H28N4O3.HCl","hydrochloride","Ruboxistaurin hydrochloride,  LY333531 hydrochloride","Cl.CN(C)CC1CC[N]2C=C(C3=C2C=CC=C3)C4=C(C(=O)NC4=O)C5=C[N](CCO1)C6=C5C=CC=C6",3.861,3,1,2]
["S7668","Picropodophyllin (PPP)","c6","L8000-18","in 10mM DMSO","Apoptosis related,IGF-1R","Protein Tyrosine Kinase","Picropodophyllin (PPP, AXL1717) is a IGF-1R inhibitor with IC50 of 1 nM. It displays selectivity for IGF-1R and does not coinhibit tyrosine phosphorylation the IR, or of a selected panel of receptors less related to IGF-IR(FGF-R, PDGF-R, OR EGF-R). Picropodophyllin (PPP) induces apoptosis with antineoplastic activity.",414.41,"477-47-4",{"v":82,"d":"82.00"},197.87,"<1","N/A","http://selleckchem.com/products/picropodophyllin-ppp.html","C22H22O8","free base","AXL1717","COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(O)C4=CC5=C(OCO5)C=C24",2.111,7,1,4]
["S7678","Sacubitril/valsartan (LCZ696)","d6","L8000-18","in 10mM DMSO","Angiotensin Receptor,Apoptosis related,Neprilysin","Proteases","Sacubitril/valsartan (LCZ696, Sacubitril, Valsartan), consisting of valsartan and sacubitril in 1:1 molar ratio, is an orally bioavailable, dual-acting angiotensin receptor-neprilysin inhibitor (ARNi) for hypertension and heart failure. Phase 3.",915.98,"936623-90-4",{"v":30,"d":"30.00"},32.75,{"v":100,"d":"100.00"},109.17,"http://selleckchem.com/products/lcz696.html","C24H29N5O3.C24H29NO5.5/2H2O.3Na","Sodium salt hydrate","Sacubitril, Valsartan","[Na+].[Na+].[Na+].CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NN=N[NH]3)C(C(C)C)C(O)=O.CCOC(=O)C(C)CC(CC4=CC=C(C=C4)C5=CC=CC=C5)NC(=O)CCC(O)=O",8.591,9,2,22]
["S7721","Monomethyl auristatin E (MMAE)","e6","L8000-18","in 10mM DMSO","ADC Cytotoxin,Microtubule Associated","Cytoskeletal Signaling","Monomethyl auristatin E (MMAE, SGD-1010) is a synthetic antineoplastic agent, which is linked to a monoclonal antibody (MAB). It is also a microtubule-disrupting agent .",717.98,"474645-27-7",{"v":100,"d":"100.00"},139.28,"<1","N/A","http://selleckchem.com/products/monomethyl-auristatin-e-mmae.html","C39H67N5O7","free base","SGD-1010","CCC(C)C(C(CC(=O)N1CCCC1C(OC)C(C)C(=O)NC(C)C(O)C2=CC=CC=C2)OC)N(C)C(=O)C(NC(=O)C(NC)C(C)C)C(C)C",{"v":3.46,"d":"3.460"},6,4,20]
["S7754","Gilteritinib (ASP2215)","f6","L8000-18","in 10mM DMSO","Axl,FLT3","Protein Tyrosine Kinase","Gilteritinib (ASP2215) is a small-molecule FLT3/AXL inhibitor with IC50 values of 0.29 nM and 0.73 nM for FLT3 and AXL, respectively. It inhibits FLT3 at an IC50 value that was approximately 800-fold more potent than the concentration required to inhibit c-KIT (230 nM).",552.71,"1254053-43-4",{"v":100,"d":"100.00"},180.93,"<1","N/A","http://selleckchem.com/products/gilteritinib-asp2215.html","C29H44N8O3","free base","N/A","CCC1=NC(=C(NC2=CC=C(N3CCC(CC3)N4CCN(C)CC4)C(=C2)OC)N=C1NC5CCOCC5)C(N)=O",2.401,5,3,9]
["S7781","Sunitinib (SU11248)","g6","L8000-18","in 10mM DMSO","Apoptosis related,Autophagy,c-Kit,IRE1,PDGFR,VEGFR","Protein Tyrosine Kinase","Sunitinib (SU11248) is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit. Sunitinib is also a dose-dependent inhibitor of the autophosphorylation activity of IRE1α. Sunitinib induces autophagy and apoptosis.",398.47,"557795-19-4",{"v":25,"d":"25.00"},62.74,"<1","N/A","http://selleckchem.com/products/sunitinib.html","C22H27FN4O2","free base","SU11248","CCN(CC)CCNC(=O)C1=C(C)[NH]C(=C1C)/C=C/2C(=O)NC3=C2C=C(F)C=C3",2.997,2,3,7]
["S7782","Dasatinib Monohydrate","h6","L8000-18","in 10mM DMSO","Bcr-Abl,c-Kit,Src","Angiogenesis","Dasatinib Monohydrate (BMS-354825) is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.",506.02,"863127-77-9",{"v":21,"d":"21.00"},{"v":41.5,"d":"41.50"},"<1","N/A","http://selleckchem.com/products/dasatinib-monohydrate.html","C22H28ClN7O3S","Monohydrate","BMS-354825 Monohydrate","O.CC1=NC(=CC(=N1)NC2=NC=C(S2)C(=O)NC3=C(C)C=CC=C3Cl)N4CCN(CCO)CC4",3.232,4,3,7]
["S7783","Combretastatin A4","a7","L8000-18","in 10mM DMSO","Microtubule Associated","Cytoskeletal Signaling","Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.Phase 3.",316.35,"117048-59-6",{"v":63,"d":"63.00"},199.15,"<1","N/A","http://selleckchem.com/products/combretastatin-a4.html","C18H20O5","free base","N/A","COC1=C(O)C=C(\\C=C/C2=CC(=C(OC)C(=C2)OC)OC)C=C1",3.508,4,1,6]
["S7784","Fumagillin","b7","L8000-18","in 10mM DMSO","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics","Microbiology","Fumagillin(Amebacilin,NSC9168) is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.",458.54,"23110-15-8",{"v":92,"d":"92.00"},200.64,"<1","N/A","http://selleckchem.com/products/fumagillin.html","C26H34O7","free base","Amebacilin,NSC9168","COC1C(CCC2(CO2)C1C3(C)OC3CC=C(C)C)OC(=O)\\C=C\\C=C\\C=C\\C=C\\C(O)=O",3.421,6,0,11]
["S7786","Erlotinib (OSI-774)","c7","L8000-18","in 10mM DMSO","Autophagy,EGFR","Protein Tyrosine Kinase","Erlotinib (OSI-774, CP358774, NSC 718781, Tarceva) is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Erlotinib induces autophagy.",393.44,"183321-74-6",{"v":78,"d":"78.00"},198.25,"<1","N/A","http://selleckchem.com/products/erlotinib.html","C22H23N3O4","free base","CP358774, NSC 718781, Tarceva","COCCOC1=C(OCCOC)C=C2C(=NC=NC2=C1)NC3=CC=CC(=C3)C#C",4.309,6,1,10]
["S7787","Docetaxel Trihydrate","d7","L8000-18","in 10mM DMSO","Microtubule Associated","Cytoskeletal Signaling","Docetaxel (RP56976, NSC 628503), an analog of paclitaxel, is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules.",861.93,"148408-66-6",{"v":100,"d":"100.00"},116.02,"<1","N/A","http://selleckchem.com/products/docetaxel-trihydrate.html","C43H53NO14.3H2O","Trihydrate","RP56976 (NSC 628503) Trihydrate","O.O.O.CC(=O)OC12COC1CC(O)C3(C)C2C(OC(=O)C4=CC=CC=C4)C5(O)CC(OC(=O)C(O)C(NC(=O)OC(C)(C)C)C6=CC=CC=C6)C(=C(C(O)C3=O)C5(C)C)C",1.964,10,4,13]
["S7810","Afatinib (BIBW2992) Dimaleate","e7","L8000-18","in 10mM DMSO","Autophagy,EGFR,HER2","Protein Tyrosine Kinase","Afatinib (BIBW2992) Dimaleate irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant. Afatinib (BIBW2992) Dimaleate induces autophagy.",717.18,"850140-73-7",{"v":100,"d":"100.00"},139.44,"<1","N/A","http://selleckchem.com/products/afatinib-bibw2992-dimaleate.html","C24H25ClFN5O3.2C4H4O4","Dimaleate","N/A","CN(C)C/C=C/C(=O)NC1=C(OC2CCOC2)C=C3N=CN=C(NC4=CC=C(F)C(=C4)Cl)C3=C1.OC(=O)\\C=C/C(O)=O.OC(=O)\\C=C/C(O)=O",{"v":0.96,"d":"0.960"},9,2,12]
["S7818","Pexidartinib (PLX3397)","f7","L8000-18","in 10mM DMSO","Apoptosis related,c-Kit,CSF-1R,FLT3","Protein Tyrosine Kinase","Pexidartinib (PLX3397) is an oral, potent multi-targeted receptor tyrosine kinase inhibitor of CSF-1R, Kit (c-Kit), and FLT3 with IC50 of 20 nM, 10 nM and 160 nM, respectively. Pexidartinib (PLX3397) induces apoptosis and necrosis with antitumor activity. Phase 3.",417.81,"1029044-16-3",{"v":83,"d":"83.00"},198.65,"<1","N/A","http://selleckchem.com/products/pexidartinib-plx3397.html","C20H15ClF3N5","free base","N/A","FC(F)(F)C1=NC=C(CNC2=NC=C(CC3=C[NH]C4=NC=C(Cl)C=C34)C=C2)C=C1",4.811,3,2,6]
["S7834","Cyclo (-RGDfK)","g7","L8000-18","in 10mM DMSO","Integrin","Cytoskeletal Signaling","Cyclo (-RGDfK) is a potent and selective αvβ3 integrin inhibitor.",717.69,"500577-51-5",{"v":100,"d":"100.00"},139.34,{"v":84,"d":"84.00"},117.04,"http://selleckchem.com/products/cyclo-rgdfk.html","C29H42F3N9O9","free base","N/A","NCCCCC1NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CCCNC(N)=N)NC1=O.OC(=O)C(F)(F)F",-4.172,7,8,14]
["S7844","Cyclo(RGDyK)","h7","L8000-18","in 10mM DMSO","Integrin","Cytoskeletal Signaling","Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.",847.72,"250612-42-1",{"v":100,"d":"100.00"},117.96,{"v":100,"d":"100.00"},117.96,"http://selleckchem.com/products/cyclo-rgdyk.html","C31H43F6N9O12","ditrifluoroacetic acid","N/A","NCCCCC1NC(=O)C(CC2=CC=C(O)C=C2)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CCCNC(N)=N)NC1=O.OC=O.OC(=O)C(F)(F)F.FC(F)F",{"v":-3.67,"d":"-3.670"},8,10,14]
["S7856","Tenofovir Alafenamide (GS-7340)","a8","L8000-18","in 10mM DMSO","Reverse Transcriptase","Microbiology","Tenofovir Alafenamide (GS-7340) is a prodrug of tenofovir, which is a reverse transcriptase inhibitor, used to treat HIV and Hepatitis B.",476.47,"379270-37-8",{"v":95,"d":"95.00"},199.38,"<1","N/A","http://selleckchem.com/products/tenofovir-alafenamide-gs-7340.html","C21H29N6O5P","free base","N/A","CC(C)OC(=O)C(C)N[P](=O)(COC(C)C[N]1C=NC2=C1N=CN=C2N)OC3=CC=CC=C3",1.526,8,2,12]
["S7858","Dibutyryl-cAMP (Bucladesine)","b8","L8000-18","in 10mM DMSO","PDE,PKA","GPCR & G Protein","Dibutyryl-cAMP (Bucladesine, dbcAMP) is a cell-permeable PKA activator by mimicing the action of endogenous cAMP. Dibutyryl-cAMP (Bucladesine) is also a phosphodiesterase (PDE) inhibitor.",491.37,"16980-89-5",{"v":98,"d":"98.00"},199.44,{"v":98,"d":"98.00"},199.44,"http://selleckchem.com/products/dibutyryl-camp-bucladesine.html","C18H23N5NaO8P","sodium salt","dbcAMP","CCCC(=O)NC1=NC=NC2=C1N=C[N]2C3OC4CO[P](=O)(O[Na])OC4C3OC(=O)CCC",1.028,10,1,9]
["S7867","Oleuropein","c8","L8000-18","in 10mM DMSO","Anti-infection,Apoptosis related,Aromatase,PPAR","Immunology & Inflammation","Oleuropein is an antioxidant polyphenol isolated from olive leaf. Oleuropein exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Oleuropein inhibits PPARγ activity. Oleuropein exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity. Oleuropein also inhibits aromatase. Oleuropein induces apoptosis. Phase 2.",540.51,"32619-42-4",{"v":100,"d":"100.00"},185.01,{"v":100,"d":"100.00"},185.01,"http://selleckchem.com/products/oleuropein.html","C25H32O13","free base","N/A","COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)\\C(=C\\C)C1CC(=O)OCCC3=CC(=C(O)C=C3)O",0.166,7,6,11]
["S7935","Y-39983 HCl","d8","L8000-18","in 10mM DMSO","ROCK","Cell Cycle","Y-39983 HCl (Y-33075) is a selective rho-associated protein kinase(ROCK) inhibitor with an IC50 of 3.6 nM.",353.25,"173897-44-4",{"v":63,"d":"63.00"},178.34,{"v":63,"d":"63.00"},178.34,"http://selleckchem.com/products/y-39983-hcl.html","C16H16N4O.2HCl","dihydrochloride","Y-33075 HCl","Cl.Cl.CC(N)C1=CC=C(C=C1)C(=O)NC2=C3C=C[NH]C3=NC=C2",2.204,2,3,3]
["S7952","Ozanimod (RPC1063)","e8","L8000-18","in 10mM DMSO","S1P Receptor","GPCR & G Protein","Ozanimod (RPC1063) is a selective oral S1P Receptor 1 modulator. Phase 3.",404.46,"1306760-87-1",{"v":81,"d":"81.00"},200.27,"<1","N/A","http://selleckchem.com/products/ozanimod-rpc1063.html","C23H24N4O3","free base","N/A","CC(C)OC1=CC=C(C=C1C#N)C2=NC(=NO2)C3=CC=CC4=C3CCC4NCCO",3.291,4,2,7]
["S7953","ETC-1002","f8","L8000-18","in 10mM DMSO","AMPK,ATP-citrate lyase,LDL","PI3K/Akt/mTOR","ETC-1002 (Bempedoic acid, ESP-55016),also known as Bempedoic acid, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies.ETC-1002 is an activator of hepatic AMP-activated protein kinase (AMPK). It has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM).",344.49,"738606-46-7",{"v":68,"d":"68.00"},197.39,"<1","N/A","http://selleckchem.com/products/etc-1002.html","C19H36O5","free base","Bempedoic acid, ESP-55016","CC(C)(CCCCCC(O)CCCCCC(C)(C)C(O)=O)C(O)=O",{"v":5.18,"d":"5.180"},2,1,14]
["S7954","CP21R7 (CP21)","g8","L8000-18","in 10mM DMSO","GSK-3,Wnt/beta-catenin","Stem Cells & Wnt","CP21R7 (CP21) is a potent and selective GSK-3β inhibitor that can potently activate canonical Wnt signalling.",317.34,"125314-13-8",{"v":63,"d":"63.00"},198.53,"<1","N/A","http://selleckchem.com/products/cp21r7-cp21.html","C19H15N3O2","free base","N/A","C[N]1C=C(C2=C1C=CC=C2)C3=C(C(=O)NC3=O)C4=CC=CC(=C4)N",2.315,2,2,2]
["S7960","Larotrectinib (LOXO-101) sulfate","h8","L8000-18","in 10mM DMSO","Apoptosis related,Trk receptor","Protein Tyrosine Kinase","Larotrectinib sulfate (LOXO-101, ARRY-470) is an oral potent and selective ATP-competitive inhibitor of tropomyosin receptor kinases (TRK). Larotrectinib inhibition of TRKs induces cellular apoptosis and G1 cell-cycle arrest.",526.51,"1223405-08-0",{"v":100,"d":"100.00"},189.93,"<1","N/A","http://selleckchem.com/products/loxo-101.html","C21H22F2N6O2.H2SO4","sulfate","ARRY-470, Larotrectinib","OC1CCN(C1)C(=O)NC2=C3N=C(C=C[N]3N=C2)N4CCCC4C5=CC(=CC=C5F)F.O[S](O)(=O)=O",1.374,3,2,3]
["S7975","Favipiravir (T-705)","a9","L8000-18","in 10mM DMSO","COVID-19,DNA/RNA Synthesis,Influenza Virus","DNA Damage/DNA Repair","Favipiravir (T-705) is a potent and selective RNA-dependent RNA polymerase inhibitor, used to treat influenza virus infections.",{"v":157.1,"d":"157.10"},"259793-96-9",{"v":31,"d":"31.00"},197.33,{"v":5,"d":"5.00"},31.83,"http://selleckchem.com/products/favipiravir-t-705.html","C5H4FN3O2","free base","N/A","NC(=O)C1=NC(=CN=C1O)F",-0.157,3,2,1]
["S7998","Entrectinib (RXDX-101)","b9","L8000-18","in 10mM DMSO","ALK,Autophagy,ROS1,Trk receptor","Protein Tyrosine Kinase","Entrectinib (RXDX-101, NMS-E628) is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. Entrectinib (RXDX-101) induces autophagy. Phase 2.",560.64,"1108743-60-7",{"v":100,"d":"100.00"},178.37,"<1","N/A","http://selleckchem.com/products/entrectinib-rxdx-101.html","C31H34F2N6O2","free base","NMS-E628","CN1CCN(CC1)C2=CC=C(C(=O)NC3=N[NH]C4=C3C=C(CC5=CC(=CC(=C5)F)F)C=C4)C(=C2)NC6CCOCC6",4.952,3,3,7]
["S8016","Vonoprazan Fumarate (TAK-438)","c9","L8000-18","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Vonoprazan Fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. Phase 3.",461.46,"1260141-27-2",{"v":62,"d":"62.00"},134.36,"<1","N/A","http://selleckchem.com/products/tak-438.html","C17H16FN3O2S.C4H4O4","Fumarate","N/A","CNCC1=C[N](C(=C1)C2=CC=CC=C2F)[S](=O)(=O)C3=CC=CN=C3.OC(=O)\\C=C\\C(O)=O",0.017,5,1,7]
["S8034","Apremilast (CC-10004)","e9","L8000-18","in 10mM DMSO","PDE,TNF-alpha","Metabolism","Apremilast (CC-10004) is a potent and orally active PDE4 and TNF-α inhibitor with IC50 of 74 nM and 77 nM, respectively.",{"v":460.5,"d":"460.50"},"608141-41-9",{"v":92,"d":"92.00"},199.78,"<1","N/A","http://selleckchem.com/products/apremilast-cc-10004.html","C22H24N2O7S","free base","CC-10004","CCOC1=C(OC)C=CC(=C1)C(C[S](C)(=O)=O)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(C)=O",1.509,7,1,8]
["S8041","Cobimetinib (GDC-0973)","f9","L8000-18","in 10mM DMSO","Apoptosis related,MEK","MAPK","Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, showing more than 100-fold selectively for MEK1 over MEK2 and showed no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Cobimetinib induces apoptosis. Phase 3.",531.31,"934660-93-2",{"v":100,"d":"100.00"},188.21,"<1","N/A","http://selleckchem.com/products/cobimetinib-gdc-0973-rg7420.html","C21H21F3IN3O2","free base","RG7420,XL518","OC1(CN(C1)C(=O)C2=C(NC3=CC=C(I)C=C3F)C(=C(F)C=C2)F)C4CCCCN4",3.701,1,2,4]
["S8048","Venetoclax (ABT-199)","g9","L8000-18","in 10mM DMSO","Autophagy,Bcl-2","Apoptosis","Venetoclax (ABT-199, GDC-0199) is a Bcl-2-selective inhibitor with Ki of <0.01 nM in cell-free assays, >4800-fold more selective versus Bcl-xL and Bcl-w, and no activity to Mcl-1. Venetoclax is reported to induce cell growth suppression, apoptosis, cell cycle arrest, and autophagy in triple negative breast cancer MDA-MB-231 cells. Phase 3.",868.44,"1257044-40-8",{"v":100,"d":"100.00"},115.15,"<1","N/A","http://selleckchem.com/products/abt-199.html","C45H50ClN7O7S","free base","GDC-0199","CC1(C)CCC(=C(C1)C2=CC=C(Cl)C=C2)CN3CCN(CC3)C4=CC(=C(C=C4)C(=O)N[S](=O)(=O)C5=CC=C(NCC6CCOCC6)C(=C5)[N+]([O-])=O)OC7=CN=C8[NH]C=CC8=C7",{"v":7.94,"d":"7.940"},6,3,13]
["S8051","Macitentan (ACT 064992)","h9","L8000-18","in 10mM DMSO","Endothelin Receptor","GPCR & G Protein","Macitentan (ACT 064992) is an orally active, non-peptide, dual ETA/ETB (endothelin) receptor antagonist with IC50 of 0.5 nM/391 nM.",588.27,"441798-33-0",{"v":100,"d":"100.00"},169.99,"<1","N/A","http://selleckchem.com/products/macitentan.html","C19H20Br2N6O4S","free base","ACT 064992","CCCN[S](=O)(=O)NC1=NC=NC(=C1C2=CC=C(Br)C=C2)OCCOC3=NC=C(Br)C=N3",3.671,8,2,11]
["S8067","Vorapaxar (MK-5348)","a10","L8000-18","in 10mM DMSO","PAR","GPCR & G Protein","Vorapaxar (SCH 530348, MK-5348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM.",492.58,"618385-01-6",{"v":99,"d":"99.00"},200.98,"<1","N/A","http://selleckchem.com/products/vorapaxar.html","C29H33FN2O4","free base","SCH 530348","CCOC(=O)NC1CCC2C(C1)CC3C(C(C)OC3=O)C2\\C=C\\C4=CC=C(C=N4)C5=CC=CC(=C5)F",5.261,5,1,6]
["S8101","CB-5083","b10","L8000-18","in 10mM DMSO","ATPase,p97","Transmembrane Transporters","CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor with IC50 of 11 nM. Phase 1.",413.47,"1542705-92-9",{"v":82,"d":"82.00"},198.32,"<1","N/A","http://selleckchem.com/products/cb-5083.html","C24H23N5O2","free base","N/A","CC1=CC2=C(C=CC=C2C(N)=O)[N]1C3=NC4=C(COCC4)C(=N3)NCC5=CC=CC=C5",3.748,4,2,5]
["S8116","Acalabrutinib (ACP-196)","c10","L8000-18","in 10mM DMSO","BTK","Angiogenesis","Acalabrutinib (ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor with an IC50 of 3 nM, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity over ibrutinib with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, respectively) and no activity against EGFR.",465.51,"1420477-60-6",{"v":93,"d":"93.00"},199.78,"<1","N/A","http://selleckchem.com/products/acalabrutinib.html","C26H23N7O2","free base","N/A","CC#CC(=O)N1CCCC1C2=NC(=C3[N]2C=CN=C3N)C4=CC=C(C=C4)C(=O)NC5=NC=CC=C5",2.699,5,2,5]
["S8133","Resiquimod (R-848)","d10","L8000-18","in 10mM DMSO","HCV,IFN,Interleukins,TLR,TNF-alpha","Immunology & Inflammation","Resiquimod (R-848, S28463) is an immune response modifier that acts as a potent TLR 7/TLR 8 agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α. Resiquimod reduces hepatitis C virus (HCV) infection. Phase 2.",314.38,"144875-48-9",{"v":63,"d":"63.00"},200.39,"<1","N/A","http://selleckchem.com/products/resiquimod.html","C17H22N4O2","free base","S28463","CCOCC1=NC2=C([N]1CC(C)(C)O)C3=C(C=CC=C3)N=C2N",1.919,3,1,5]
["S8134","Radotinib","e10","L8000-18","in 10mM DMSO","Bcr-Abl","Angiogenesis","Radotinib (IY-5511) is a selective BCR-ABL1 tyrosine kinase inhibitor with IC50 of 34 nM, used to treat Chronic Myeloid Leukemia.",{"v":530.5,"d":"530.50"},"926037-48-1",{"v":100,"d":"100.00"},{"v":188.5,"d":"188.50"},"<1","N/A","http://selleckchem.com/products/radotinib.html","C27H21F3N8O","free base","IY-5511","CC1=C[N](C=N1)C2=CC(=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C)C(=C3)NC4=NC=CC(=N4)C5=NC=CN=C5",4.362,6,2,7]
["S8135","Riociguat (BAY 63-2521)","f10","L8000-18","in 10mM DMSO","Guanylate Cyclase","GPCR & G Protein","Riociguat (BAY 63-2521) is an oral soluble guanylate cyclase (GC) stimulator, used in the treatment of ipulmonary hypertension.",422.42,"625115-55-1",{"v":84,"d":"84.00"},198.85,"<1","N/A","http://selleckchem.com/products/riociguat-bay-63-2521.html","C20H19FN8O2","free base","N/A","COC(=O)N(C)C1=C(N)N=C(N=C1N)C2=N[N](CC3=CC=CC=C3F)C4=NC=CC=C24",2.341,6,2,5]
["S8136","Sivelestat (ONO-5046)","g10","L8000-18","in 10mM DMSO","Serine Protease","Proteases","Sivelestat (ONO5046, LY544349, EI546) is a potent and selective inhibitor of neutrophil elastase with IC50 of 44nM. It almost shows no activity at a range of other proteases.",434.46,"127373-66-4",{"v":86,"d":"86.00"},197.95,"<1","N/A","http://selleckchem.com/products/sivelestat-ono-5046.html","C20H22N2O7S","Free Base","ONO5046, LY544349, EI546","CC(C)(C)C(=O)OC1=CC=C(C=C1)[S](=O)(=O)NC2=CC=CC=C2C(=O)NCC(O)=O",2.321,6,2,9]
["S8144","Halofuginone","h10","L8000-18","in 10mM DMSO","DNA/RNA Synthesis,TGF-beta/Smad","DNA Damage/DNA Repair","Halofuginone (RU-19110) is the competitively inhibitor of  prolyl-tRNA synthetase with Ki of 18.3 nM.It could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in mammal.",414.68,"55837-20-2",{"v":20,"d":"20.00"},48.23,"<1","N/A","http://selleckchem.com/products/halofuginone.html","C16H17BrClN3O3","free base","RU-19110","OC1CCCNC1CC(=O)CN2C=NC3=CC(=C(Cl)C=C3C2=O)Br",1.648,3,2,4]
["S8183","Pimavanserin tartrate","a11","L8000-18","in 10mM DMSO","5-HT Receptor","GPCR & G Protein","Pimavanserin tartrate(ACP-103) is a potent and selective serotonin 5-HT2A inverse agonist with pIC50 of 8.73, used to treat psychosis associated with Parkinson’s disease.",{"v":1005.2,"d":"1005.20"},"706782-28-7",{"v":100,"d":"100.00"},99.48,{"v":100,"d":"100.00"},99.48,"http://selleckchem.com/products/pimavanserin.html","C50H68F2N6O4.C4H6O6","tartrate","ACP-103","CC(C)COC1=CC=C(CNC(=O)N(CC2=CC=C(F)C=C2)C3CCN(C)CC3)C=C1.CC(C)COC4=CC=C(CNC(=O)N(CC5=CC=C(F)C=C5)C6CCN(C)CC6)C=C4.OC(C(O)C(O)=O)C(O)=O",0.735,6,4,19]
["S8205","Enasidenib (AG-221)","b11","L8000-18","in 10mM DMSO","Dehydrogenase","Metabolism","Enasidenib (AG-221) is a first-in-class, oral, potent, reversible, selective inhibitor of the IDH2 mutant enzyme.",473.38,"1446502-11-9",{"v":94,"d":"94.00"},198.57,"<1","N/A","http://selleckchem.com/products/ag-221-enasidenib.html","C19H17F6N7O","free base","N/A","CC(C)(O)CNC1=NC(=NC(=N1)NC2=CC=NC(=C2)C(F)(F)F)C3=NC(=CC=C3)C(F)(F)F",4.878,5,2,8]
["S8206","Ivosidenib (AG-120)","c11","L8000-18","in 10mM DMSO","Dehydrogenase","Metabolism","Ivosidenib (AG-120) is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity.",582.96,"1448347-49-6",{"v":100,"d":"100.00"},171.54,"<1","N/A","http://selleckchem.com/products/ag-120-Ivosidenib.html","C28H22ClF3N6O3","free base","N/A","FC1=CN=CC(=C1)N(C(C(=O)NC2CC(F)(F)C2)C3=C(Cl)C=CC=C3)C(=O)C4CCC(=O)N4C5=NC=CC(=C5)C#N",3.004,5,1,7]
["S8294","Olmutinib (BI 1482694)","d11","L8000-18","in 10mM DMSO","BTK,EGFR","Protein Tyrosine Kinase","Olmutinib (BI 1482694) is a novel third-generation epidermal growth factor receptor (EGFR) mutation-specific tyrosine kinase inhibitor (TKI). Also a potent inhibitor of Bruton's tyrosine kinase.",486.59,"1353550-13-6",{"v":97,"d":"97.00"},199.35,"<1","N/A","http://selleckchem.com/products/olmutinib-hm61713-bi-1482694.html","C26H26N6O2S","free base","HM61713","CN1CCN(CC1)C2=CC=C(NC3=NC(=C4SC=CC4=N3)OC5=CC=CC(=C5)NC(=O)C=C)C=C2",5.449,4,2,7]
["S8362","Tucatinib","e11","L8000-18","in 10mM DMSO","EGFR,HER2","Protein Tyrosine Kinase","Tucatinib (Irbinitinib, ONT-380, ARRY-380) is an oral, potent, selective, reversible and ATP-competitive small-molecule inhibitor of ErbB-2 (also called HER2) with IC50s of 8 nM and 7 nM for ErbB-2 and p95 HER2, respectively in cell-based assays, showing ~500-fold selective for HER2 vs EGFR. It has potential antineoplastic activity.",480.52,"937263-43-9",{"v":96,"d":"96.00"},199.78,"<1","N/A","http://selleckchem.com/products/arry-380-ont-380.html","C26H24N8O2","free base","Irbinitinib, ONT-380, ARRY-380","CC1=CC(=CC=C1OC2=CC3=NC=N[N]3C=C2)NC4=NC=NC5=CC=C(NC6=NC(C)(C)CO6)C=C45",4.744,7,2,6]
["S8401","Erdafitinib (JNJ-42756493)","f11","L8000-18","in 10mM DMSO","Apoptosis related,c-Kit,c-RET,CSF-1R,FGFR,PDGFR,VEGFR","Angiogenesis","Erdafitinib (JNJ-42756493) is a potent and selective orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. Erdafitinib also binds to RET (c-RET), CSF-1R, PDGFR-α/PDGFR-β, FLT4, Kit (c-Kit) and VEGFR-2 and induces cellular apoptosis.",446.54,"1346242-81-6",{"v":89,"d":"89.00"},199.31,"<1","N/A","http://selleckchem.com/products/jnj-42756493-erdafitinib.html","C25H30N6O2","free base","N/A","COC1=CC(=CC(=C1)N(CCNC(C)C)C2=CC3=NC(=CN=C3C=C2)C4=C[N](C)N=C4)OC",3.943,5,1,9]
["S8432","Troglitazone (CS-045)","g11","L8000-18","in 10mM DMSO","Apoptosis related,Autophagy,Ferroptosis,PPAR","Metabolism","Troglitazone (Rezulin, Romglizone, Prelay, CS045, Romozin) is a potent agonist for the peroxisome proliferator-activated receptor-(PPAR) that is a ligand activated transcription factor regulating cell differentiation and growth. Troglitazone induces autophagy, apoptosis and necroptosis in bladder cancer cells. Troglitazone prevents RSL3-induced ferroptosis and lipid peroxidation in Pfa1 cells.",441.54,"97322-87-7",{"v":88,"d":"88.00"},{"v":199.3,"d":"199.30"},"<1","N/A","http://selleckchem.com/products/troglitazone-cs-045.html","C24H27NO5S","free base","Rezulin, Romglizone, Prelay, Romozin","CC1=C(O)C(=C2CCC(C)(COC3=CC=C(CC4SC(=O)NC4=O)C=C3)OC2=C1C)C",5.682,4,2,5]
["S8539","TAS-102","h11","L8000-18","in 10mM DMSO","DNA/RNA Synthesis,Thymidylate Synthase","DNA Damage/DNA Repair","TAS-102 (Trifluridine-Tipiracil Hydrochloride Mixture) is an orally administered combination of a thymidine-based nucleic acid analogue, trifluridine, and a thymidine phosphorylase inhibitor, tipiracil hydrochloride.",435.76,"733030-01-8",{"v":100,"d":"100.00"},114.74,{"v":15,"d":"15.00"},17.21,"http://selleckchem.com/products/tas-102.html","C10H11F3N2O5.0.5C9H11ClN4O2.0.5HCl","hydrochloride","Trifluridine-Tipiracil Hydrochloride Mixture","Cl.OCC1OC(CC1O)N2C=C(C(=O)NC2=O)C(F)(F)F.OCC3OC(CC3O)N4C=C(C(=O)NC4=O)C(F)(F)F.ClC5=C(CN6CCCC6=N)NC(=O)NC5=O",-1.951,8,8,8]
["S8558","Tofogliflozin(CSG 452)","a2","L8000-19","in 10mM DMSO","SGLT","GPCR & G Protein","Tofogliflozin (CSG 452) is a novel sodium-glucose co-transporter 2(SGLT2) inhibitor with IC50 values of 2.9 nM and 8444 nM for hSGLT2 and hSGLT1, respectively.",404.45,"1201913-82-7",{"v":84,"d":"84.00"},207.69,{"v":4,"d":"4.00"},9.89,"http://selleckchem.com/products/tofogliflozin-csg-452.html","C22H26O6.H2O","hydrate","N/A","O.CCC1=CC=C(CC2=CC3=C(COC34OC(CO)C(O)C(O)C4O)C=C2)C=C1",{"v":1.92,"d":"1.920"},2,4,4]
["S8567","Tucidinostat (Chidamide)","b2","L8000-19","in 10mM DMSO","HDAC","Epigenetics","Tucidinostat (Chidamide, HBI-8000, CS-055) is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.",390.41,"1616493-44-7",{"v":78,"d":"78.00"},199.79,"<1","N/A","http://selleckchem.com/products/tucidinostat-chidamide.html","C22H19FN4O2","free base","HBI-8000, CS-055","NC1=C(NC(=O)C2=CC=C(CNC(=O)\\C=C\\C3=CC=CN=C3)C=C2)C=C(F)C=C1",2.182,3,3,6]
["S8594","Tirofiban Hydrochloride","c2","L8000-19","in 10mM DMSO","Integrin","Cytoskeletal Signaling","Tirofiban Hydrochloride (MK-383) is the hydrochloride salt form of tirofiban, a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation. It is more soluable than Tirofiban.",495.07,"150915-40-5",{"v":95,"d":"95.00"},191.89,{"v":95,"d":"95.00"},191.89,"http://selleckchem.com/products/tirofiban-hydrochlorid.html","C22H36N2O5S.HCl.H2O","hydrochloride hydrate","MK-383 Hydrochloride","O.Cl.CCCC[S](=O)(=O)NC(CC1=CC=C(OCCCCC2CCNCC2)C=C1)C(O)=O",0.922,4,2,14]
["S8615","Sodium dichloroacetate (DCA)","d2","L8000-19","in 10mM DMSO","Apoptosis related,Dehydrogenase,NKCC,ROS","Metabolism","Sodium dichloroacetate (DCA, Dichloroacetic acid, bichloroacetic acid, BCA), a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress Na+-K+-2Cl- cotransporter and a mitochondrial potassium-ion channel axis. Sodium dichloroacetate increases reactive oxygen species (ROS) generation, triggers apoptosis in cancer cells, and inhibits tumor growth.",150.92,"2156-56-1",{"v":30,"d":"30.00"},198.78,{"v":30,"d":"30.00"},198.78,"http://selleckchem.com/products/sodium-dichloroacetate-dca.html","C2HCl2O2.Na","sodium salt","Dichloroacetic acid, bichloroacetic acid, BCA","[Na]OC(=O)C(Cl)Cl",1.081,2,0,2]
["S8726","Anlotinib (AL3818) dihydrochloride","e2","L8000-19","in 10mM DMSO","VEGFR","Protein Tyrosine Kinase","Anlotinib (AL3818) is a highly potent and selective VEGFR2 inhibitor with IC50 less than 1 nM. It has broad-spectrum antitumor potential in clinical trials. Please use saline solution rather than PBS for dilutions. PBS may cause precipitation.",480.36,"1360460-82-7",{"v":96,"d":"96.00"},199.85,{"v":96,"d":"96.00"},199.85,"http://selleckchem.com/products/anlotinib-al3818.html","C23H22FN3O3.2HCl","dihydrochloride","N/A","Cl.Cl.COC1=C(OCC2(N)CC2)C=C3N=CC=C(OC4=C(F)C5=C([NH]C(=C5)C)C=C4)C3=C1",4.469,4,2,6]
["S8757","Ripretinib (DCC-2618)","f2","L8000-19","in 10mM DMSO","c-Kit,PDGFR","Protein Tyrosine Kinase","DCC-2618 is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of the tumor-associated antigens (TAA) mast/stem cell factor receptor (SCFR) Kit (c-Kit) and PDGFR-alpha, with IC50 values of 4 nM, 8 nM, 18 nM, 5 nM and 14 nM for WT Kit (c-Kit), V654A Kit (c-Kit), T670I Kit (c-Kit), D816H Kit (c-Kit) and D816V Kit (c-Kit), respectively.",510.36,"1442472-39-0",{"v":100,"d":"100.00"},195.94,"<1","N/A","http://www.selleckchem.com/products/ripretinib-dcc-2618.html","C24H21BrFN5O2","Free Base","N/A","CCN1C(=O)C(=CC2=C1C=C(NC)N=C2)C3=C(Br)C=C(F)C(=C3)NC(=O)NC4=CC=CC=C4",4.129,3,3,5]
["S8791","Zanubrutinib (BGB-3111)","g2","L8000-19","in 10mM DMSO","BTK","Protein Tyrosine Kinase","Zanubrutinib (BGB-3111) is a potent, specific and irreversible BTK inhibitor that has been shown to have a lower off-target inhibitory activity on other kinases, including ITK, JAK3 and EGFR.",471.55,"1691249-45-2",{"v":94,"d":"94.00"},199.34,"<1","N/A","http://www.selleck.cn/products/zanubrutini-bgb-3111.html","C27H29N5O3","Free Base","N/A","NC(=O)C1=C2NCCC(C3CCN(CC3)C(=O)C=C)[N]2N=C1C4=CC=C(OC5=CC=CC=C5)C=C4",3.478,4,2,6]
["S8817","Almonertinib (HS-10296)","h2","L8000-19","in 10mM DMSO","EGFR","Protein Tyrosine Kinase","Almonertinib (Aumolertinib, HS-10296, Ameile) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR.",525.64,"1899921-05-1",{"v":100,"d":"100.00"},190.24,"<1","N/A","http://www.selleck.cn/products/hs-10296.html","C30H35N7O2","Free Base","Aumolertinib, Ameile","COC1=C(NC2=NC(=CC=N2)C3=C[N](C4CC4)C5=C3C=CC=C5)C=C(NC(=O)C=C)C(=C1)N(C)CCN(C)C",{"v":5.16,"d":"5.160"},4,2,11]
["S9002","L-Fucose","a3","L8000-19","in 10mM DMSO","Others","Others","Fucose (6-Deoxy-L-Galactose, L-fucopyranose) is found on N-linked glycans on the mammalian, insect and plant cell surface. L-Fucose is claimed to have application in cosmetics, pharmaceuticals, and dietary supplements.",164.16,"2438-80-4",{"v":33,"d":"33.00"},201.03,"N/A","N/A","https://www.selleckchem.com/products/l-fucose.html","C6H12O5","free base","6-Deoxy-L-Galactose, L-fucopyranose","CC(O)C(O)C(O)C(O)C=O",-1.903,1,4,4]
["S9007","2'-deoxyguanosine","b3","L8000-19","in 10mM DMSO","Others","Others","2'-deoxyguanosine is a kind of purine nucleoside.",267.24,"961-07-9",{"v":53,"d":"53.00"},198.32,"N/A","N/A","https://www.selleckchem.com/products/2-deoxyguanosine-monohydrate.html","C10H13N5O4","free base","2'-Deoxy-D-guanosine","NC1=NC2=C(N=C[N]2C3CC(O)C(CO)O3)C(=O)N1",-1.613,4,4,2]
["S9032","Sanguinarine","c3","L8000-19","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Sanguinarine (Pseudochelerythrine, Sanguinarin, Sanguinarium), a benzophenanthridine alkaloid known as an anti-inflammatory agent, is a potent inhibitor of NF-κB activation.",332.33,"2447-54-3",{"v":44,"d":"44.00"},{"v":132.4,"d":"132.40"},"N/A","N/A","https://www.selleckchem.com/products/sanguinarine.html","C20H14NO4","free base","Pseudochelerythrine, Sanguinarin, Sanguinarium","C[N+]1=CC2=C3OCOC3=CC=C2C4=C1C5=CC6=C(OCO6)C=C5C=C4",3.987,4,0,0]
["S9042","Wedelolactone","d3","L8000-19","in 10mM DMSO","Caspase,IκB/IKK","NF-κB","Wedelolactone, a medicinal plant-derived natural compound, is an inhibitor of IKK that is critical for activation of NF-κB by mediating phosphorylation and degradation of IκBα. Wedelolactone is also an inhibitor of caspase-11.",314.25,"524-12-9",{"v":63,"d":"63.00"},200.48,"N/A","N/A","https://www.selleckchem.com/products/wedelolactone.html","C16H10O7","free base","FW73945","COC1=CC2=C(C(=C1)O)C3=C(C(=O)O2)C4=C(O3)C=C(O)C(=C4)O",2.803,4,3,1]
["S9046","Berberine","e3","L8000-19","in 10mM DMSO","Bacterial","Microbiology","Berberine (Umbellatine), an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic.",336.36,"2086-83-1",{"v":45,"d":"45.00"},133.78,"N/A","N/A","https://www.selleckchem.com/products/berberine.html","C20H18NO4","free base","Umbellatine","COC1=C(OC)C2=C(C=C1)C=C3C4=C(CC[N+]3=C2)C=C5OCOC5=C4",3.962,4,0,2]
["S9063","Harringtonine","f3","L8000-19","in 10mM DMSO","Antiviral","Microbiology","Harringtonine is a natural cephalotaxine alkaloid that inhibits protein biosynthesis. It also exhibits antiviral and anticancer activities.",531.59,"26833-85-2",{"v":10,"d":"10.00"},18.81,"N/A","N/A","https://www.selleckchem.com/products/harringtonine.html","C28H37NO9","free base","FH15975","COC(=O)CC(O)(CCC(C)(C)O)C(=O)OC1C2C3=CC4=C(OCO4)C=C3CCN5CCCC25C=C1OC",1.961,7,0,10]
["S9140","Pulegone","g3","L8000-19","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Pulegone, a naturally occurring organic compound, is a fragrance and flavour ingredient.pulegone stimulates both TRPM8 and TRPA1 channel in chicken sensory neurons and suppresses the former but not the latter at high concentrations.",152.23,"89-82-7","N/A","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","https://www.selleckchem.com/products/pulegone.html","C10H16O","free base","N/A","CC1CCC(=C(C)C)C(=O)C1",2.891,1,0,0]
["S9141","Berbamine","h3","L8000-19","in 10mM DMSO","Apoptosis related,Bcr-Abl,CaMK,NF-κB","Angiogenesis","Berbamine (BA), a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan), is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF-κB. Berbamine (BA) induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca²⁺/calmodulin-dependent protein kinase II (CaMKII).",608.72,"478-61-5",{"v":100,"d":"100.00"},164.28,"N/A","N/A","https://www.selleckchem.com/products/berbamine.html","C37H40N2O6","free base","BA, BBM","COC1=C2OC3=C4C(CC5=CC=C(O)C(=C5)OC6=CC=C(CC7N(C)CCC(=C1)C7=C2)C=C6)N(C)CCC4=CC(=C3OC)OC",6.992,5,1,3]
["S9143","Ammonium Glycyrrhizate","a4","L8000-19","in 10mM DMSO","Others","Others","Ammonium glycyrrhizate (Glycamil, Glycyrram) is an ammonium salt extract isolated from licorice root and is commonly used as a flavoring agent and is also used in fragrances, and skin and hair care products.",839.96,"53956-04-0",{"v":100,"d":"100.00"},119.05,"N/A","N/A","https://www.selleckchem.com/products/ammonium-glycyrrhizate.html","C42H65NO16","free base","Glycamil, Glycyrram","N.CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O)OC6OC(C(O)C(O)C6OC7OC(C(O)C(O)C7O)C(O)=O)C(O)=O",-0.915,8,5,7]
["S9179","Catharanthine hemitartrate","b4","L8000-19","in 10mM DMSO","AChR","Neuronal Signaling","Catharanthine hemitartrate is the starting material for the synthesis of the antitumor drugs vinblastine and vincristine.",822.94,"4168-17-6",{"v":97,"d":"97.00"},199.38,"N/A","N/A","https://www.selleckchem.com/products/catharanthine-hemitartrate.html","C46H54N4O10","free base","N/A","CCC1=CC2CN3CCC4=C([NH]C5=C4C=CC=C5)C(C2)(C13)C(=O)OC.OC(C(O)C(O)=O)C(O)=O",-0.822,4,3,6]
["S9193","Aristolochic acid A","c4","L8000-19","in 10mM DMSO","AP-1,NF-κB","NF-κB","Aristolochic acid A (Aristolochic Acid I, Aristolochin, Aristolochine, TR 1736) is a carcinogenic, mutagenic, and nephrotoxic agent extracted from the flowering plant family Aristolochiaceae.Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and nuclear factor-κB (NF-κB) activities.",341.27,"313-67-7",{"v":6,"d":"6.00"},17.58,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/aristolochic-acid-a.html","C17H11NO7","Free Base","Aristolochic Acid I, Aristolochin, Aristolochine, TR 1736","COC1=CC=CC2=C3C4=C(OCO4)C=C(C(O)=O)C3=C(C=C12)[N+]([O-])=O",2.922,4,0,3]
["S9240","Isofraxidin","d4","L8000-19","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Isofraxidin (6,8-Dimethoxyumbelliferone), a bioactive coumarin compound isolated from the functional foods Siberian ginseng and Apium graveolens, is an anti-bacterial, anti-oxidant, and anti-inflammatory agent.",222.19,"486-21-5",{"v":44,"d":"44.00"},198.03,"N/A","N/A","https://www.selleckchem.com/products/isofraxidin.html","C11H10O5","free base","6,8-Dimethoxyumbelliferone","COC1=CC2=C(OC(=O)C=C2)C(=C1O)OC",1.625,4,1,2]
["S9249","Securinine","e4","L8000-19","in 10mM DMSO","GABA Receptor","Neuronal Signaling","Securinine, a major natural alkaloid product from the root of the plant Securinega suffruticosa, acts as a γ-amino butyric acid (GABA) receptor antagonist.",217.26,"5610-40-2",{"v":44,"d":"44.00"},202.52,"N/A","N/A","https://www.selleckchem.com/products/securinine.html","C13H15NO2","free base","N/A","O=C1OC23CC(C=CC2=C1)N4CCCCC34",1.449,2,0,0]
["S9321","Topotecan","f4","L8000-19","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Topotecan(NSC609699,Nogitecan,SKFS 104864A) is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.",421.45,"123948-87-8",{"v":84,"d":"84.00"},199.31,"N/A","N/A","https://www.selleckchem.com/products/topotecan.html","C23H23N3O5","free base","NSC609699,Nogitecan,SKFS 104864A","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC(=C(CN(C)C)C5=C4)O)C2=O",1.577,4,1,3]
["S9338","Octyl gallate","g4","L8000-19","in 10mM DMSO","Others","Microbiology","Octyl gallate (Progallin O, n-Ocyl gallate, Stabilizer GA-8, Gallic acid octyl ester), a widely used food additive, shows antimicrobial and antioxidant activity.",282.33,"1034-01-1",{"v":56,"d":"56.00"},198.35,"N/A","N/A","https://www.selleckchem.com/products/octyl-gallate.html","C15H22O5","free base","Progallin O, n-Ocyl gallate, Stabilizer GA-8, Gallic acid octyl ester","CCCCCCCCOC(=O)C1=CC(=C(O)C(=C1)O)O",4.112,2,3,9]
["S9354","Oxalic acid","h4","L8000-19","in 10mM DMSO","Others","Others","Oxalic acid (Ethanedioic acid, Wood bleach) is a strong dicarboxylic acid occurring in many plants and vegetables.",90.03,"144-62-7",{"v":18,"d":"18.00"},199.92,"N/A","N/A","https://www.selleckchem.com/products/oxalic-acid.html","C2H2O4","free base","Ethanedioic acid, Wood bleach","OC(=O)C(O)=O",-0.429,2,0,1]
["S9368","ADP","a5","L8000-19","in 10mM DMSO","Others","Others","ADP (Adenosine diphosphate, adenosine pyrophosphate, Adenosine 5'-diphosphate) is an important organic compound in metabolism and is essential to the flow of energy in living cells.",{"v":427.2,"d":"427.20"},"58-64-0",{"v":6,"d":"6.00"},14.04,"N/A","N/A","https://www.selleckchem.com/products/adp.html","C10H15N5O10P2","free base","Adenosine diphosphate, adenosine pyrophosphate, Adenosine 5'-diphosphate","NC1=NC=NC2=C1N=C[N]2C3OC(CO[P](O)(=O)O[P](O)(O)=O)C(O)C3O",-2.239,6,3,6]
["S9382","Thymine","b5","L8000-19","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Thymine (5-methyluracil) is one of the four nucleobases in the nucleic acid of DNA.",126.11,"65-71-4",{"v":25,"d":"25.00"},198.23,"N/A","N/A","https://www.selleckchem.com/products/thymine.html","C5H6N2O2","free base","5-methyluracil","CC1=CNC(=O)NC1=O",-0.566,2,2,0]
["S9413","Yangonin","c5","L8000-19","in 10mM DMSO","Cannabinoid Receptor,Fungal","GPCR & G Protein","Yangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors.",258.27,"500-62-9",{"v":51,"d":"51.00"},197.47,"N/A","N/A","https://www.selleckchem.com/products/yangonin.html","C15H14O4","free base","Y100550","COC1=CC=C(C=C1)/C=C/C2=CC(=CC(=O)O2)OC",2.211,4,0,4]
["S9459","Mecamylamine Hydrochloride","d5","L8000-19","in 10mM DMSO","AChR","Neuronal Signaling","Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist. Mecamylamine hydrochloride is also a ganglionic blocker. Mecamylamine hydrochloride can across the blood-brain barrier. Mecamylamine hydrochloride can be used in the research of neuropsychiatric disorders, hypertension, antidepressant area.",203.75,"826-39-1",{"v":41,"d":"41.00"},201.23,{"v":-1,"d":"-1.00"},"N/A","N/A","C11H21N · HCl","Hydrochloride","N/A","Cl.CNC1(C)C2CCC(C2)C1(C)C",2.565,0,1,1]
["S9463","Demecarium Bromide","e5","L8000-19","in 10mM DMSO","AChR","Neuronal Signaling","Demecarium Bromide (BC-48) is a potent cholinesterase inhibitor, with an apparent affinity (Kiapp) of 0.15 μM. Demecarium Bromide (BC-48) is used as a glaucoma agent.",716.59,"56-94-0",{"v":100,"d":"100.00"},139.55,{"v":-1,"d":"-1.00"},"N/A","N/A","C32H52Br2N4O4","Bromide","N/A","[Br-].[Br-].CN(CCCCCCCCCCN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C)C(=O)OC2=CC=CC(=C2)[N+](C)(C)C",-0.615,4,0,17]
["S9502","Madecassic acid","f5","L8000-19","in 10mM DMSO","COX,Immunology & Inflammation related,Interleukins,NF-κB,NOS,TNF-alpha","Immunology & Inflammation","Madecassic acid (Brahmic acid), a natural triterpene first isolated from C. asiatica, has diverse anti-inflammatory and anti-diabetic effects, blocking NF-κB activation in macrophages and causing by iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 inhibition.",{"v":504.7,"d":"504.70"},"18449-41-7",{"v":100,"d":"100.00"},198.13,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/madecassic-acid.html","C30H48O6","Free Base","Brahmic acid","CC1CCC2(CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(CO)C5C(O)CC34C)C2C1C)C(O)=O",3.265,1,4,2]
["S9507","(−)-Norepinephrine","h5","L8000-19","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","(−)-Norepinephrine (Arterenol, Levarterenol, L-Noradrenaline) is a natural neurotransmitter and hormone. It is an agonist of adrenergic receptors with Ki values of 330, 56, and 740 nM for α1, α2, and β1 adrenoceptors, respectively.",169.18,"51-41-2",{"v":11,"d":"11.00"},65.02,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/norepinephrine.html","C8H11NO3","Free Base","Arterenol, Levarterenol, L-Noradrenaline","NCC(O)C1=CC(=C(O)C=C1)O",-0.059,0,4,2]
["S9510","Protriptyline hydrochloride","a6","L8000-19","in 10mM DMSO","5-HT Receptor","Neuronal Signaling","Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline. Protriptyline is a tricyclic secondary amine with antidepressant property which acts by inhibition of serotonin and norepinephrine reuptake.",299.84,"1225-55-4",{"v":60,"d":"60.00"},200.11,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/protriptyline-hydrochloride.html","C19H22ClN","hydrochloride","N/A","Cl.CNCCCC1C2=C(C=CC=C2)C=CC3=C1C=CC=C3",4.423,0,1,4]
["S4421","Josamycin","b6","L8000-19","in 10mM DMSO","Antibiotics","Microbiology","Josamycin (EN-141, Kitasamycin A3, Leucomycin A3, Turimycin A5) is a macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.",827.99,"16846-24-5",{"v":100,"d":"100.00"},120.77,"<1","N/A","http://www.selleck.cn/products/josamycin.html","C42H69NO15","Free Base","EN-141, Kitasamycin A3, Leucomycin A3, Turimycin A5","COC1C(CC(=O)OC(C)C/C=C/C=C/C(O)C(C)CC(CC=O)C1OC2OC(C)C(OC3CC(C)(O)C(OC(=O)CC(C)C)C(C)O3)C(C2O)N(C)C)OC(C)=O",2.957,12,2,14]
["S6589","Norethisterone Enanthate","c6","L8000-19","in 10mM DMSO","Others","Others","Norethisterone Enanthate (Norethindrone Enanthate) is a form of progestogen-only injectable birth control which is used to prevent pregnancy in women.",410.59,"3836-23-5",{"v":82,"d":"82.00"},199.71,"<1","N/A","http://www.selleck.cn/products/norethisterone-enanthate.html","C27H38O3","Free Base","Norethindrone Enanthate","CCCCCCC(=O)OC1(CCC2C3CCC4=CC(=O)CCC4C3CCC12C)C#C",7.186,3,0,7]
["S6593","Methylprednisolone sodium succinate","d6","L8000-19","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Methylprednisolone sodium succinate (U-9088, 6α-Methylprednisolone 21-hemisuccinate Sodium) is a corticosteroid medication that reduces inflammation.",496.53,"2375-03-3",{"v":99,"d":"99.00"},199.38,{"v":99,"d":"99.00"},199.38,"http://www.selleck.cn/products/methylprednisolone-sodium-succinate.html","C26H33NaO8","Sodium succinate","U-9088, 6α-Methylprednisolone 21-hemisuccinate Sodium","[Na+].CC1CC2C3CCC(O)(C(=O)COC(=O)CCC([O-])=O)C3(C)CC(O)C2C4(C)C=CC(=O)C=C14",0.262,4,1,7]
["S6626","Brequinar (DUP785)","e6","L8000-19","in 10mM DMSO","Dehydrogenase","Metabolism","Brequinar (DUP785, NSC 368390) is an inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of ∼20 nM in vitro.",375.37,"96187-53-0",{"v":37,"d":"37.00"},98.57,"<1","N/A","http://www.selleck.cn/products/brequinar.html","C23H15F2NO2","Free Base","NSC 368390","CC1=C(N=C2C=CC(=CC2=C1C(O)=O)F)C3=CC=C(C=C3)C4=C(F)C=CC=C4",6.008,2,0,3]
["S6631","Belotecan (CKD-602) hydrochloride","f6","L8000-19","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Belotecan (CKD-602) is a potent DNA topoisomerase I inhibitor that exerts a clinical anticancer effect on various types of tumor.",469.96,"213819-48-8",{"v":47,"d":"47.00"},100.01,{"v":4,"d":"4.00"},8.51,"http://www.selleck.cn/products/belotecan-ckd-602-hydrochloride.html","C25H28ClN3O4","Hydrochloride","N/A","Cl.CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC=CC5=C4CCNC(C)C)C2=O",2.713,4,1,5]
["S6742","Etofenamate","g6","L8000-19","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Etofenamate is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.",369.34,"30544-47-9","N/A","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","http://www.selleck.cn/products/etofenamate.html","C18H18F3NO4","Free Base","N/A","OCCOCCOC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)C=CC=C1",3.507,3,2,10]
["S8781","Selpercatinib (LOXO-292)","a7","L8000-19","in 10mM DMSO","c-RET","Apoptosis","Selpercatinib (LOXO-292, ARRY-192) is a potent and specific RET (c-RET) inhibitor with IC50 values of 1 nM, 2 nM, 2 nM, 4 nM, 2 nM, 2 nM for WT RET, RET V804M, RET V804L, RET A883F, RET M918T and RET S891A respectively.",{"v":525.6,"d":"525.60"},"2152628-33-4",{"v":25,"d":"25.00"},47.56,"<1","N/A","http://www.selleck.cn/products/loxo-292.html","C29H31N7O3","Free Base","ARRY-192","COC1=NC=C(CN2C3CC2CN(C3)C4=NC=C(C=C4)C5=CC(=C[N]6N=CC(=C56)C#N)OCC(C)(C)O)C=C1",2.884,5,0,8]
["S9015","Homoharringtonine (CGX-635)","b7","L8000-19","in 10mM DMSO","STAT","JAK/STAT","Homoharringtonine (CGX-635, Omacetaxine mepesuccinate, HHT, Myelostat, NSC 141633), a plant alkaloid with antitumor properties, inhibits protein translation by preventing the initial elongation step of protein synthesis via an interaction with the ribosomal A-site. Homoharringtonine reversiblely inhibits IL-6-induced STAT3 Tyrosine 705 phosphorylation and reduced anti-apoptotic proteins expression.",545.62,"26833-87-4",{"v":10,"d":"10.00"},18.33,"N/A","N/A","https://www.selleckchem.com/products/homoharringtonine.html","C29H39NO9","free Base","Omacetaxine mepesuccinate, HHT, Myelostat, NSC 141633","COC(=O)CC(O)(CCCC(C)(C)O)C(=O)OC1C2C3=CC4=C(OCO4)C=C3CCN5CCCC25C=C1OC",2.418,7,0,11]
["S9024","3-O-Acetyl-11-keto-β-boswellic acid (AKBA)","c7","L8000-19","in 10mM DMSO","Lipoxygenase","Metabolism","3-O-Acetyl-11-keto-β-boswellic acid (AKBA), the major active ingredient of the gum resin from Boswellia serrata and Boswellia carteri Birdw., exerts anti-inflammatory therapeutic effects and noncompetitively inhibits 5-lipoxygenase, topoisomerase, and leukocyte elastase.",512.72,"67416-61-9",{"v":100,"d":"100.00"},195.04,"N/A","N/A","https://www.selleckchem.com/products/akba.html","C32H48O5","Salt","FA42758","CC1CCC2(C)CCC3(C)C(=CC(=O)C4C5(C)CCC(OC(C)=O)C(C)(C5CCC34C)C(O)=O)C2C1C",6.081,4,0,3]
["S9050","Boldine","d7","L8000-19","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Boldine, isolated from Peumus boldus, has alpha-adrenergic antagonist activities in vascular tissue with anti-oxidant, hepatoprotective, cytoprotective, antipyretic and anti-inflammatory effects.",327.37,"476-70-0",{"v":10,"d":"10.00"},30.55,"N/A","N/A","https://www.selleckchem.com/products/boldine.html","C19H21NO4","free base","1, 10-Dimethoxy-2, 9-dihydroxyaporphine; ex Peumus boldus","COC1=C(O)C=C2CC3N(C)CCC4=CC(=C(OC)C(=C34)C2=C1)O",3.083,2,2,2]
["S9086","Dihydrocapsaicin","e7","L8000-19","in 10mM DMSO","TRP Channel","Transmembrane Transporters","Dihydrocapsaicin (6,7-Dihydrocapsaicin, 8-Methyl-N-vanillylnonanamide, CCRIS1589), found in pepper (C. annuum), is a potential nutriceutical.DHC is a selective TRPV1 agonist.",307.43,"19408-84-5",{"v":10,"d":"10.00"},32.53,"N/A","N/A","https://www.selleckchem.com/products/dihydrocapsaicin.html","C18H29NO3","free base","6,7-Dihydrocapsaicin, 8-Methyl-N-vanillylnonanamide, CCRIS1589","COC1=C(O)C=CC(=C1)CNC(=O)CCCCCCC(C)C",4.354,2,2,10]
["S9102","Magnolin","f7","L8000-19","in 10mM DMSO","ERK","MAPK","Magnolin is a natural compound abundantly found in Magnolia flos targeting ERK1 (IC50=87 nM) and ERK2 (IC50=16.5 nM) and inhibits cell transformation induced by tumor promoters such as epidermal growth factor (EGF).",416.46,"31008-18-1",{"v":83,"d":"83.00"},{"v":199.3,"d":"199.30"},"N/A","N/A","https://www.selleckchem.com/products/magnolin.html","C23H28O7","free Base","N/A","COC1=C(OC)C=C(C=C1)C2OCC3C2COC3C4=CC(=C(OC)C(=C4)OC)OC",2.618,7,0,7]
["S9110","Morin","g7","L8000-19","in 10mM DMSO","Others","Others","Morin (Al-Morin, Aurantica, Calico Yellow, Toxylon pomiferum), a constituent of various woods, has a role as an antioxidant, a metabolite, an antihypertensive agent, a hepatoprotective agent, a neuroprotective agent, an anti-inflammatory agent, an antineoplastic agent, an antibacterial agent, a DNA topoisomerase inhibitor and an angiogenesis modulating agent.",302.24,"480-16-0",{"v":10,"d":"10.00"},33.09,"N/A","N/A","https://www.selleckchem.com/products/morin.html","C15H10O7","free base","Al-Morin, Aurantica, Calico Yellow, Toxylon pomiferum","OC1=CC(=C(C=C1)C2=C(O)C(=O)C3=C(O2)C=C(O)C=C3O)O",{"v":1.63,"d":"1.630"},2,5,1]
["S9111","Isorhamnetin","h7","L8000-19","in 10mM DMSO","Tyrosinase","Proteases","Isorhamnetin (3-methylquercetin, 3'-Methoxyquercetin, Isorhamnetol), a natural flavonol aglycon, is a tyrosinase inhibitor and has antioxidant activity.",316.26,"480-19-3",{"v":63,"d":"63.00"},{"v":199.2,"d":"199.20"},"N/A","N/A","https://www.selleckchem.com/products/isorhamnetin.html","C16H12O7","free base","3-methylquercetin, 3'-Methoxyquercetin, Isorhamnetol","COC1=C(O)C=CC(=C1)C2=C(O)C(=O)C3=C(O2)C=C(O)C=C3O",1.856,3,4,2]
["S9123","Eriodictyol","a8","L8000-19","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Eriodictyol, a flavonoid extracted from yerba santa, has anti-inflammatory and antioxidant activities and taste-modifying properties.",288.25,"552-58-9",{"v":57,"d":"57.00"},197.74,"N/A","N/A","https://www.selleckchem.com/products/eriodictyol.html","C15H12O6","free base","N/A","OC1=CC2=C(C(=O)CC(O2)C3=CC(=C(O)C=C3)O)C(=C1)O",2.131,2,4,1]
["S9183","Ruscogenin","b8","L8000-19","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Ruscogenin, a major steroidal sapogenin of traditional Chinese herb Radix Ophiopogon japonicus, has been reported to exert significant anti-inflammatory and anti-thrombotic activities.",430.62,"472-11-7",{"v":86,"d":"86.00"},199.71,"N/A","N/A","https://www.selleckchem.com/products/ruscogenin.html","C27H42O4","free base","N/A","CC1CCC2(OC1)OC3CC4C5CC=C6CC(O)CC(O)C6(C)C5CCC4(C)C3C2C",3.408,2,2,0]
["S9192","Vitexin","c8","L8000-19","in 10mM DMSO","Others","Others","Vitexin (Apigenin-8-C-glucoside), an naturally occuring apigenin flavone glycoside, acts as a platelet aggregation and alpha-glucosidase inhibitor and shows antineoplastic activity.",432.38,"3681-93-4",{"v":47,"d":"47.00"},{"v":108.7,"d":"108.70"},"N/A","N/A","https://www.selleckchem.com/products/vitexin.html","C21H20O10","free base","Apigenin-8-C-glucoside","OCC1OC(C(O)C(O)C1O)C2=C(O)C=C(O)C3=C2OC(=CC3=O)C4=CC=C(O)C=C4",0.018,3,7,3]
["S9224","Dehydroandrographolide Succinate","d8","L8000-19","in 10mM DMSO","Antiviral,Bacterial","Microbiology","Dehydroandrographolide succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, has antibacterial and antiviral effects.",532.58,"786593-06-4",{"v":100,"d":"100.00"},187.77,"N/A","N/A","https://www.selleckchem.com/products/dehydroandrographolide-succinate.html","C28H36O10","free base","N/A","CC1(COC(=O)CCC(O)=O)C(CCC2(C)C1CCC(=C)C2\\C=C\\C3=CCOC3=O)OC(=O)CCC(O)=O",3.027,8,0,13]
["S9248","Homoorientin","e8","L8000-19","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Homoorientin (Isoorientin, Luteolin-6-C-glucoside) is a flavone that acts as a radical scavenger and an antineoplastic agent.",448.38,"4261-42-1",{"v":90,"d":"90.00"},200.72,"N/A","N/A","https://www.selleckchem.com/products/homoorientin.html","C21H20O11","free Base","Isoorientin, Luteolin-6-C-glucoside","OCC1OC(C(O)C(O)C1O)C2=C(O)C3=C(OC(=CC3=O)C4=CC(=C(O)C=C4)O)C=C2O",-0.224,3,8,3]
["S9270","Dracohodin perochlorate","f8","L8000-19","in 10mM DMSO","Others","Others","Dracohodin perochlorate, extracted from Dragon's blood, is widely used in traditional Chinese medicine, especially in wound healing.",366.75,"125536-25-6",{"v":73,"d":"73.00"},199.05,"N/A","N/A","https://www.selleckchem.com/products/dracohodin-perochlorate.html","C17H15ClO7","free base","N/A","COC1=C(C)C(=CC2=C1C=CC(=[O+]2)C3=CC=CC=C3)O.[O-][Cl](=O)(=O)=O",1.785,1,1,2]
["S9285","Fargesin","g8","L8000-19","in 10mM DMSO","Adrenergic Receptor","Neuronal Signaling","Fargesin is a neolignan isolated from Magnolia plants. It is a potential β1AR antagonist through cAMP/PKA pathway.",{"v":370.4,"d":"370.40"},"31008-19-2",{"v":36,"d":"36.00"},97.19,"N/A","N/A","https://www.selleckchem.com/products/fargesin.html","C21H22O6","free base","N/A","COC1=CC=C(C=C1OC)C2OCC3C2COC3C4=CC5=C(OCO5)C=C4",2.436,6,0,4]
["S9288","Casticin","h8","L8000-19","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Casticin (Vitexicarpin), as the major active substance in Lithospermum erythrorhyzon, had been reported to mediate multiple pharmacological activities such as antioxidation, antiviral, cardiovascular protection, antineoplastic and anti-inflammation.",374.34,"479-91-4",{"v":75,"d":"75.00"},200.35,"N/A","N/A","https://www.selleckchem.com/products/casticin.html","C19H18O8","free base","Vitexicarpin","COC1=C(O)C=C(C=C1)C2=C(OC)C(=O)C3=C(O2)C=C(OC)C(=C3O)OC",2.291,6,2,5]
["S9294","Gelsemine","a9","L8000-19","in 10mM DMSO","GlyR","Transmembrane Transporters","Gelsemine, a principal alkaloid from Gelsemium sempervirens Ait., is a highly toxic compound and may be a glycine receptor agonist with significantly higher binding affinity for some of these receptors than its native agonist, glycine.",{"v":322.4,"d":"322.40"},"509-15-9",{"v":64,"d":"64.00"},198.51,"N/A","N/A","https://www.selleckchem.com/products/gelsemine.html","C20H22N2O2","free base","N/A","CN1CC2(C=C)C3CC4OCC3C1C2C45C(=O)NC6=CC=CC=C56",0.891,2,1,1]
["S9416","Triptonide","b9","L8000-19","in 10mM DMSO","Wnt/beta-catenin","Stem Cells & Wnt","Triptonide, isolated from the roots of Tripterygium wilfordii, can effectively inhibit canonical Wnt/β-catenin signaling by targeting the downstream C-terminal transcription domain of β-catenin or a nuclear component associated with β-catenin. It is also an antineoplastic agent, an anti-inflammatory agent and an immunosuppressive agent.",358.39,"38647-11-9",{"v":71,"d":"71.00"},198.11,"N/A","N/A","https://www.selleckchem.com/products/triptonide.html","C20H22O6","free base","N/A","CC(C)C12OC1C3OC34C5(C)CCC6=C(COC6=O)C5CC7OC47C2=O",1.259,6,0,1]
["S9519","Fadrozole (CGS16949A)","c9","L8000-19","in 10mM DMSO","Aromatase","Endocrinology & Hormones","Fadrozole (CGS16949A) is a potent, selective, nonsteroidal inhibitor of aromatase with an IC50 of 4.5 nM and selectivity over other cytochrome P-450 enzymes.",223.27,"102676-47-1",{"v":45,"d":"45.00"},201.55,"<1","N/A","http://www.selleck.cn/products/fadrozole.html","C14H13N3","Free Base","CGS16949A","N#CC1=CC=C(C=C1)C2CCCC3=CN=C[N]23",2.271,1,0,1]
["S2307","Roquinimex","d9","L8000-19","in 10mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Roquinimex (FCF 89, Linomide, LS 2616) is a novel immunomodulator augmenting natural killer (NK) cell activity and T-lymphocyte related effector functions. Roquinimex is a potent oral active tumor antiangiogenic agent. Roquinimex inhibits the secretion of TNF-α.",308.33,"84088-42-6",{"v":62,"d":"62.00"},201.08,"<1","N/A","http://www.selleck.cn/products/roquinimex.html","C18H16N2O3","Free Base","FCF 89, Linomide, LS 2616","CN(C1=CC=CC=C1)C(=O)C2=C(O)C3=C(C=CC=C3)N(C)C2=O",1.871,2,1,2]
["S2426","Tirapazamine","e9","L8000-19","in 10mM DMSO","Others","Others","Tirapazamine (NSC 130181, SR 259075, SR 4233, Tirazone, WIN 59075) is a new anticancer drug in solid tumours. Tirapazamine exhibits preferential tumour cell killing and high specific toxicity to cells at low oxygen tensions.",178.15,"27314-97-2",{"v":36,"d":"36.00"},202.08,"<1","N/A","http://www.selleck.cn/products/tirapazamine.html","C7H6N4O2","Free Base","NSC 130181, SR 259075, SR 4233, Tirazone, WIN 59075","NC1=[N+]([O-])C2=CC=CC=C2[N+](=N1)[O-]",-0.565,1,1,0]
["S6676","Ebselen","f9","L8000-19","in 10mM DMSO","COVID-19,HIV","Microbiology","Ebselen (DR 3305, SPI-1005, PZ-51, CCG-39161) is a small-molecule capsid inhibitor of HIV-1 Replication with IC50 of 46.1 nM in TR-FRET assay.",274.18,"60940-34-3",{"v":55,"d":"55.00"},{"v":200.6,"d":"200.60"},"<1","N/A","http://www.selleck.cn/products/ebselen.html","C13H9NOSe","Free Base","DR 3305, SPI-1005, PZ-51, CCG-39161","O=C1N([Se]C2=C1C=CC=C2)C3=CC=CC=C3",3.227,1,0,1]
["S2288","Rubitecan","g9","L8000-19","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Rubitecan (9-NC, 9-Nitro-camptothecin, Partaject Orathecin, Partaject rubitecan, RFS 2000) is a topoisomerase I inhibitor extracted from the bark and leaves of the Camptotheca acuminata tree, which is native to China. Rubitecan is an oral camptothecin with antitumour activity.",393.35,"91421-42-0",{"v":58,"d":"58.00"},147.45,"<1","N/A","http://www.selleckchem.com/products/rubitecan.html","C20H15N3O6","Free Base","9-NC, 9-Nitro-camptothecin, Partaject Orathecin, Partaject rubitecan, RFS 2000","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC=C(C5=C4)[N+]([O-])=O)C2=O",{"v":1.64,"d":"1.640"},4,0,2]
["S2447","Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222)","h9","L8000-19","in 10mM DMSO","ADC Cytotoxin,Microtubule Associated","Cytoskeletal Signaling","Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222, Antibiotic C 15003P3) is a potent inhibitor of tubulin polymerization with IC50 of 3.4 μM.",635.14,"66584-72-3",{"v":100,"d":"100.00"},157.45,"<1","N/A","http://www.selleckchem.com/products/ansamitocin-p-3-maytansinol-isobutyrate.html","C32H43ClN2O9","Free Base","Antibiotic C 15003P3","COC1\\C=C\\C=C(C)\\CC2=CC(=C(Cl)C(=C2)OC)N(C)C(=O)CC(OC(=O)C(C)C)C3(C)OC3C(C)C4CC1(O)NC(=O)O4",4.445,8,1,5]
["S6848","3'-Fluoro-3'-deoxythymidine (Alovudine)","a10","L8000-19","in 10mM DMSO","DNA/RNA Synthesis,HIV,Reverse Transcriptase","Microbiology","3'-Fluoro-3'-deoxythymidine (Alovudine, CL 184824, FddThd, FLT, MIV-310) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the  chemotherapy of pancreatic cancer.",244.22,"25526-93-6",{"v":49,"d":"49.00"},200.64,{"v":20,"d":"20.00"},81.89,"http://www.selleckchem.com/products/3-fluoro-3-deoxythymidine.html","C10H13FN2O4","Free Base","CL 184824, FddThd, FLT, MIV-310","CC1=CN(C2CC(F)C(CO)O2)C(=O)NC1=O",-0.298,3,2,2]
["S0088","Pemigatinib (INCB054828)","b10","L8000-19","in 10mM DMSO","FGFR","Angiogenesis","Pemigatinib (INCB054828, Pemazyre) is an orally active and selective inhibitor of FGFR with IC50 of 0.4 nM, 0.5 nM, 1.2 nM and 30 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. Pemigatinib has the potential for cholangiocarcinoma.",{"v":487.5,"d":"487.50"},"1513857-77-6",{"v":40,"d":"40.00"},82.05,"<1","N/A","http://www.selleckchem.com/products/pemigatinib-incb054828.html","C24H27F2N5O4","free base","Pemazyre","CCN1C(=O)N(CC2=C1C3=C([NH]C(=C3)CN4CCOCC4)N=C2)C5=C(F)C(=CC(=C5F)OC)OC",2.596,5,1,6]
["S2440","Vindesine sulfate","c10","L8000-19","in 10mM DMSO","Microtubule Associated","Cytoskeletal Signaling","Vindesine sulfate (Eldesine, Eldisine, Desacetyl Vinblastine amide, Desacetylvinblastine amide, DAVA, DVA, VDS), a vinca alkaloid derived from Catharanthus roseus, is a potent inhibitor of mitosis with antineoplastic activities. Vindesine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death.",{"v":852,"d":"852.00"},"59917-39-4",{"v":100,"d":"100.00"},117.37,{"v":100,"d":"100.00"},117.37,"http://www.selleckchem.com/products/vindesine-sulfate.html","C43H57N5O11S","sulfate","Eldesine, Eldisine, Desacetyl Vinblastine amide, Desacetylvinblastine amide, DAVA, DVA, VDS","CCC1(O)CC2CN(CCC3=C([NH]C4=CC=CC=C34)C(C2)(C(=O)OC)C5=C(OC)C=C6N(C)C7C(O)(C(O)C8(CC)C=CCN9CCC7(C89)C6=C5)C(N)=O)C1.O[S](O)(=O)=O",3.047,4,3,7]
["S3273","Hypericin","d10","L8000-19","in 10mM DMSO","Hydroxylase,MAO,P450 (e.g. CYP17),PKC,Reverse Transcriptase,Telomerase","Metabolism","Hypericin (Hyp, HY) is a naturally occurring substance found in the common St. John's Wort (Hypericum species) with antidepressive, antineoplastic and antiviral (human immunodeficiency and hepatitis C virus) activities. Hypericin has inhibitory effects on MAO (monoaminoxidase), PKC (protein kinase C), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450).",504.44,"548-04-9",{"v":100,"d":"100.00"},198.24,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/hypericin.html","C30H16O8","free base","Hyp, HY","CC1=C2C3=C(C)C=C(O)C4=C3C5=C6C2=C(C(=C1)O)C(=O)C7=C6C(=C(O)C=C7O)C8=C(O)C=C(O)C(=C58)C4=O",{"v":5.04,"d":"5.040"},2,6,0]
["S6852","Gossypol","e10","L8000-19","in 10mM DMSO","Apoptosis related,Bcl-2,Dehydrogenase","Apoptosis","Gossypol (BL 193) is an orally-active polyphenol isolated from cotton seeds and roots. Gossypol is a potent inhibitor of 5α-reductase 1 and 3α-hydroxysteroid dehydrogenase with IC50 of 3.33 μM and 0.52 μM in cell-free assay, respectively. Gossypol also inhibits the binding of BH3 peptide to Bcl protein with IC50 of 0.4 μM and 10 μM for Bcl-XL and Bcl-2, respectively. Gossypol induces apoptosis and cell growth inhibition in various cancer cells.",518.55,"303-45-7",{"v":100,"d":"100.00"},192.85,"<1","N/A","http://www.selleckchem.com/products/gossypol.html","C30H30O8","free base","BL 193","CC(C)C1=C(O)C(=C(C=O)C2=C1C=C(C)C(=C2O)C3=C(O)C4=C(C=C3C)C(=C(O)C(=C4C=O)O)C(C)C)O",6.592,2,6,5]
["S0323","Antineoplaston A10","f10","L8000-19","in 10mM DMSO","Ras","Apoptosis","Antineoplaston A10 is a naturally occurring substance in the human body that that can be potentially used for the treatment of glioma, lymphoma, astrocytoma and breast cancer. The main ingredient active of antineoplaston A10 (Phenylacetylglutamine, PG) inhibits RAS and promotes apoptosis.",246.26,"91531-30-5",{"v":49,"d":"49.00"},198.98,"<1","N/A","https://www.selleckchem.com/products/antineoplaston-a10.html","C13H14N2O3","Free Base","N/A","O=C1CCC(NC(=O)CC2=CC=CC=C2)C(=O)N1",0.307,3,2,3]
["S1198","Irinotecan (CPT-11)","g10","L8000-19","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Irinotecan (CPT-11, (+)-Irinotecan) is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively.",586.68,"97682-44-5",{"v":51,"d":"51.00"},86.93,"<1","N/A","https://www.selleckchem.com/products/Irinotecan-cpt-11.html","C33H38N4O6","Free Base","(+)-Irinotecan,CPT-11","CCC1=C2C=C(OC(=O)N3CCC(CC3)N4CCCCC4)C=CC2=NC5=C1CN6C(=O)C7=C(C=C56)C(O)(CC)C(=O)OC7",3.686,6,0,5]
["S1421","Staurosporine (AM-2282)","h10","L8000-19","in 10mM DMSO","ADC Cytotoxin,Antineoplastic and Immunosuppressive Antibiotics,CaMK,PKA,PKC,PKG,S6 Kinase","TGF-beta/Smad","Staurosporine (AM-2282, Antibiotic AM-2282, STS) is a potent PKC inhibitor for PKCα, PKCγ and PKCη with IC50 of 2 nM, 5 nM and 4 nM, less potent to PKCδ (20 nM), PKCε (73 nM) and little active to PKCζ (1086 nM) in cell-free assays. Also shows inhibitory activities on other kinases, such as PKA, PKG, S6K, CaMKII, etc. Phase 3.",466.53,"62996-74-1",{"v":93,"d":"93.00"},199.34,"<1","N/A","https://www.selleckchem.com/products/Staurosporine.html","C28H26N4O3","Free Base","Antibiotic AM-2282, STS","CNC1CC2OC(C)(C1OC)[N]3C4=C(C=CC=C4)C5=C6CNC(=O)C6=C7C8=CC=CC=C8[N]2C7=C35",3.819,3,2,2]
["S3141","Maleimide","a11","L8000-19","in 10mM DMSO","ADC Linker,Dyes","Others","Maleimide exhibits fluorescence quenching ability and can be used for the specific detection of thiol analytes as fluorogenic probes. Maleimide is also used for production of antibody-drug conjugate (ADC) which is used in cancer research.",97.07,"541-59-3",{"v":19,"d":"19.00"},195.74,{"v":19,"d":"19.00"},195.74,"https://www.selleckchem.com/products/maleimide.html","C4H3NO2","Free Base","N/A","O=C1NC(=O)C=C1",-0.395,2,1,0]
["S5248","Apatinib","b11","L8000-19","in 10mM DMSO","Apoptosis related,Autophagy,c-Kit,c-RET,Src,VEGFR","Protein Tyrosine Kinase","Apatinib (Rivoceranib, YN968D1) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib induces both autophagy and apoptosis.",397.47,"811803-05-1",{"v":79,"d":"79.00"},198.76,"<1","N/A","https://www.selleckchem.com/products/apatinib.html","C24H23N5O","Free Base","Rivoceranib, YN968D1","O=C(NC1=CC=C(C=C1)C2(CCCC2)C#N)C3=C(NCC4=CC=NC=C4)N=CC=C3",3.578,3,2,6]
["S6948","Lanreotide","c11","L8000-19","in 10mM DMSO","GHSR","Endocrinology & Hormones","Lanreotide (Laromustine, Angiopeptin, BIM 23014, Dermopeptin, Ipstyl, ITM-014, Somatulina, Somatuline, Lanreotidum), an analog of the native somatostatin peptide, is a physiological inhibitor of growth hormone (GH). Lanreotide also has antitumoral effects.",1096.32,"108736-35-2",{"v":100,"d":"100.00"},91.21,{"v":100,"d":"100.00"},91.21,"https://www.selleckchem.com/products/lanreotide.html","C54H69N11O10S2","Free Base","Laromustine, Angiopeptin, BIM 23014, BIM 23014C, BM 23014, Dermopeptin, Ipstyl, ITM-014, ITM-014T, Somatulina, Somatuline, Lanreotidum","CC(C)C1NC(=O)C(CCCCN)NC(=O)C(CC2=C[NH]C3=C2C=CC=C3)NC(=O)C(CC4=CC=C(O)C=C4)NC(=O)C(CSSCC(NC1=O)C(=O)NC(C(C)O)C(N)=O)NC(=O)C(N)CC5=CC6=CC=CC=C6C=C5",1.704,8,13,17]
["S6958","Treosulfan","d11","L8000-19","in 10mM DMSO","DNA alkylator","DNA Damage/DNA Repair","Treosulfan (NSC 39069, Treosulphan) is an alkylating agent used for conventional and high-dose chemotherapy regimens. Treosulfan is potently cytotoxic against pancreatic cancer cell lines.",{"v":278.3,"d":"278.30"},"299-75-2",{"v":56,"d":"56.00"},201.22,{"v":56,"d":"56.00"},201.22,"https://www.selleckchem.com/products/treosulfan.html","C6H14O8S2","Free Base","NSC 39069, Treosulphan","C[S](=O)(=O)OCC(O)C(O)CO[S](C)(=O)=O",-1.953,2,2,7]
["S9521","Pentostatin","e11","L8000-19","in 10mM DMSO","Adenosine Deaminase,DNA/RNA Synthesis","Neuronal Signaling","Pentostatin(CI-825,Deoxycoformycin) is a potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.",268.27,"53910-25-1",{"v":54,"d":"54.00"},201.29,{"v":54,"d":"54.00"},201.29,"https://www.selleckchem.com/products/pentostatin.html","C11H16N4O4","Free Base","CI-825,Deoxycoformycin","OCC1OC(CC1O)[N]2C=NC3=C2NC=NCC3O",-1.965,3,4,2]
["S9712","Fluzoparib (SHR-3162)","f11","L8000-19","in 10mM DMSO","PARP","DNA Damage/DNA Repair","Fluzoparib (SHR3162, HS10160) is a potent Poly (ADP-ribose) polymerase (PARP) inhibitor that shows anti-tumor activity, with an IC50 of 1.46±0.72 nM for PARP1.",{"v":472.4,"d":"472.40"},"1358715-18-0",{"v":94,"d":"94.00"},198.98,"<1","N/A","https://www.selleckchem.com/products/fluzoparib.html","C22H16F4N6O2","Free Base","HS10160","FC1=CC=C(CC2=NNC(=O)C3=C2C=CC=C3)C=C1C(=O)N4CC[N]5N=C(N=C5C4)C(F)(F)F",2.757,5,1,4]
["S4418","Phenol Red sodium salt","g11","L8000-19","in 10mM DMSO","Dyes,Estrogen/progestogen Receptor","Others","Phenol Red sodium salt (Phenolsulfonephthalein sodium salt) is used ubiquitously as a pH indicator in tissue culture media ranging from 6.8 (yellow) to 8.2 (red). Phenol red binds to the estrogen receptor of MCF-7 human breast cancer cells.",376.36,"34487-61-1",{"v":75,"d":"75.00"},199.28,{"v":15,"d":"15.00"},39.86,"http://www.selleckchem.com/products/phenol-red-sodium-salt.html","C19H13NaO5S","Sodium salt","Phenolsulfonephthalein sodium salt","[Na+].OC1=CC=C(C=C1)C2(O[S](=O)(=O)C3=CC=CC=C23)C4=CC=C([O-])C=C4",{"v":2.82,"d":"2.820"},1,1,2]
["S4432","Ixazomib Citrate (MLN9708)","h11","L8000-19","in 10mM DMSO","Proteasome","Proteases","Ixazomib citrate (MLN9708, Ninlaro) is a prodrug of Ixazomib (MLN2238), which is a selective, orally bioavailable inhibitor of 20S proteasome that inhibits the chymotrypsin-like proteolytic (β5) site with IC50 of 3.4 nM and Ki of 0.93 nM, respectively. Ixazomib (MLN2238) also inhibits caspase-like (β1) and trypsin-like (β2) proteolytic sites with IC50 of 31 nM and 3500 nM, respectively.",517.12,"1239908-20-3",{"v":100,"d":"100.00"},193.38,"<1","N/A","http://www.selleckchem.com/products/ixazomib-citrate.html","C20H23BCl2N2O9","Free Base","Ninlaro","CC(C)CC(NC(=O)CNC(=O)C1=C(Cl)C=CC(=C1)Cl)B2OC(=O)C(CC(O)=O)(CC(O)=O)O2",3.497,7,2,11]
["S4447","Pipobroman","a2","L8000-20","in 10mM DMSO","DNA alkylator","DNA Damage/DNA Repair","Pipobroman (PB, Vercyte), a neutral amide of piperazine, acts as an alkylating agent with antiproliferative activity.",356.05,"54-91-1",{"v":71,"d":"71.00"},199.41,"<1","N/A","http://www.selleckchem.com/products/pipobroman.html","C10H16Br2N2O2","Free Base","PB, Vercyte","BrCCC(=O)N1CCN(CC1)C(=O)CCBr",0.647,2,0,4]
["S4484","Trametinib DMSO solvate","b2","L8000-20","in 10mM DMSO","Apoptosis related,Autophagy,MEK","MAPK","Trametinib (GSK1120212, JTP-74057, Mekinist) DMSO solvate is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assay. Trametinib activates autophagy and induces apoptosis.",693.53,"1187431-43-1",{"v":50,"d":"50.00"},72.09,"<1","N/A","http://www.selleckchem.com/products/trametinib-dmso-solvate.html","C28H29FIN5O5S","Free Base","GSK1120212, JTP-74057, Mekinist","CN1C(=O)C(=C2N(C(=O)N(C3CC3)C(=O)C2=C1NC4=C(F)C=C(I)C=C4)C5=CC=CC(=C5)NC(C)=O)C.C[S](C)=O",{"v":2.86,"d":"2.860"},5,2,5]
["S4489","Tetraethylammonium chloride","c2","L8000-20","in 10mM DMSO","Potassium Channel","Transmembrane Transporters","Tetraethylammonium (TEA) chloride is a nonspecific potassium channel blocker with antitumor properties.",{"v":165.7,"d":"165.70"},"56-34-8",{"v":33,"d":"33.00"},199.16,{"v":33,"d":"33.00"},199.16,"http://www.selleckchem.com/products/tetraethylammonium-chloride.html","C8H20ClN","Free Base","TEA chloride","[Cl-].CC[N+](CC)(CC)CC",-2.314,0,0,4]
["S4895","Nilotinib hydrochloride monohydrate","d2","L8000-20","in 10mM DMSO","AMPK,Autophagy,Bcr-Abl","Angiogenesis","Nilotinib (AMN-107, Tasigna) hydrochloride monohydrate is a selective and orally bioavailable inhibitor of Bcr-Abl with IC50 < 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.",583.99,"923288-90-8",{"v":100,"d":"100.00"},171.24,"<1","N/A","http://www.selleckchem.com/products/nilotinib-hydrochloride-monohydrate.html","C28H25ClF3N7O2","Hydrochloride monohydrate","Tasigna, AMN-107 hydrochloride monohydrate","O.Cl.CC1=C[N](C=N1)C2=CC(=CC(=C2)NC(=O)C3=CC(=C(C)C=C3)NC4=NC=CC(=N4)C5=CN=CC=C5)C(F)(F)F",5.259,5,2,7]
["S4929","Enasidenib Mesylate","e2","L8000-20","in 10mM DMSO","Dehydrogenase","Metabolism","Enasidenib (Idhifa, AG-221) mesylate is an orally available, selective and potent inhibitor of mutant isocitrate dehydrogenase 2 (IDH2).",569.48,"1650550-25-6",{"v":100,"d":"100.00"},{"v":175.6,"d":"175.60"},"<1","N/A","http://www.selleckchem.com/products/enasidenib-mesylate.html","C20H21F6N7O4S","Mesylate","Idhifa, AG-221 mesylate","CC(C)(O)CNC1=NC(=NC(=N1)C2=NC(=CC=C2)C(F)(F)F)NC3=CC(=NC=C3)C(F)(F)F.C[S](O)(=O)=O",4.464,5,2,8]
["S4947","Regorafenib Hydrochloride","f2","L8000-20","in 10mM DMSO","c-Kit,c-RET,PDGFR,Raf,VEGFR","Protein Tyrosine Kinase","Regorafenib (Stivarga, BAY 73-4506) Hydrochloride is a multi-target inhibitor for VEGFR1, Murine VEGFR2/3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM, 4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.",519.28,"835621-07-3",{"v":100,"d":"100.00"},192.57,"<1","N/A","http://www.selleckchem.com/products/regorafenib-hydrochloride.html","C21H16Cl2F4N4O3","Hydrochloride","Stivarga, BAY 73-4506 hydrochloride","Cl.CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(NC(=O)NC3=CC(=C(Cl)C=C3)C(F)(F)F)C=C2)F",4.763,4,3,6]
["S4948","Rucaparib","g2","L8000-20","in 10mM DMSO","PARP","DNA Damage/DNA Repair","Rucaparib (Rubraca, AG014699, PF01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains.",323.36,"283173-50-2",{"v":65,"d":"65.00"},201.01,"<1","N/A","http://www.selleckchem.com/products/rucaparib.html","C19H18FN3O","Free Base","Rubraca, AG014699, PF01367338","CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=C3C(=CC(=C4)F)[NH]2",2.959,1,3,3]
["S4967","Ceritinib dihydrochloride","h2","L8000-20","in 10mM DMSO","ALK,IGF-1R,Serine/threonin kinase","Protein Tyrosine Kinase","Ceritinib (Zykadia, LDK378) dihydrochloride is a selective, orally bioavailable and ATP-competitive inhibitor of ALK with IC50 of 0.2 nM. Ceritinib dihydrochloride also inhibits InsR, IGF-1R and STK22D with IC50 of 7 nM, 8 nM and 23 nM, respectively. Ceritinib exhibits antitomor activity.",631.06,"1380575-43-8",{"v":13,"d":"13.00"},{"v":20.6,"d":"20.60"},"<1","N/A","http://www.selleckchem.com/products/ceritinib-dihydrochloride.html","C28H38Cl3N5O3S","Dihydrochloride","Zykadia, LDK378 dihydrochloride","Cl.Cl.CC(C)OC1=C(NC2=NC=C(Cl)C(=N2)NC3=CC=CC=C3[S](=O)(=O)C(C)C)C=C(C)C(=C1)C4CCNCC4",7.243,5,3,9]
["S5026","Irinotecan hydrochloride","a3","L8000-20","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Irinotecan (CPT-11, (+)-Irinotecan) hydrochloride is an inhibitor of Topoisomerase I (Topo I) that exhibits cytotoxicity in LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively.",623.14,"100286-90-6",{"v":100,"d":"100.00"},160.48,"<1","N/A","http://www.selleckchem.com/products/irinotecan-hydrochloride.html","C33H39ClN4O6","Hydrochloride","CPT-11 hydrochloride, (+)-Irinotecan hydrochloride","Cl.CCC1=C2CN3C(=O)C4=C(C=C3C2=NC5=C1C=C(OC(=O)N6CCC(CC6)N7CCCCC7)C=C5)C(O)(CC)C(=O)OC4",4.068,6,0,5]
["S5080","Neticonazole","b3","L8000-20","in 10mM DMSO","Fungal","Microbiology","Neticonazole (SS717) is a selecvie inhibitor of exosome biogenesis and secretion. Neticonazole exhibits Neticonazole antifungal and antitumor activity.",302.43,"130726-68-0",{"v":60,"d":"60.00"},198.39,{"v":60,"d":"60.00"},198.39,"http://www.selleckchem.com/products/neticonazole.html","C17H22N2OS","Free Base","SS717","CCCCCOC1=CC=CC=C1C(=C\\SC)/[N]2C=CN=C2",3.456,2,0,8]
["S5184","Dexamethasone palmitate","c3","L8000-20","in 10mM DMSO","Anti-infection,Glucocorticoid Receptor","Endocrinology & Hormones","Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone (DXM), is a glucocorticoid receptor agonist with a 47-fold lower affinity for the glucocorticoid receptor than DXM. Dexamethasone palmitate (DXP) exhibits anti-inflammatory activity.",630.87,"14899-36-6",{"v":100,"d":"100.00"},158.51,"<1","N/A","http://www.selleckchem.com/products/dexamethasone-palmitate.html","C38H59FO6","Free Base","DXP","CCCCCCCCCCCCCCCC(=O)OCC(=O)C1(O)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C",8.684,4,1,18]
["S5187","Ribociclib hydrochloride","d3","L8000-20","in 10mM DMSO","CDK","Cell Cycle","Ribociclib (LEE011) hydrochloride is a highly specific dual inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM, respectively.",{"v":471,"d":"471.00"},"1211443-80-9",{"v":94,"d":"94.00"},199.58,{"v":94,"d":"94.00"},199.58,"http://www.selleckchem.com/products/ribociclib-hydrochloride.html","C23H31ClN8O","Hydrochloride","LEE011 hydrochloride","Cl.CN(C)C(=O)C1=CC2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2[N]1C5CCCC5",3.282,4,2,5]
["S5188","Ribociclib succinate","e3","L8000-20","in 10mM DMSO","CDK","Cell Cycle","Ribociclib (LEE011) succinate (Kisqali) is a highly specific dual inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM, respectively.",552.63,"1374639-75-4",{"v":100,"d":"100.00"},180.95,"<1","N/A","http://www.selleckchem.com/products/ribociclib-succinate.html","C27H36N8O5","Succinate","LEE011 succinate, Kisqali","CN(C)C(=O)C1=CC2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2[N]1C5CCCC5.OC(=O)CCC(O)=O",-0.164,6,2,8]
["S5190","Crizotinib hydrochloride","f3","L8000-20","in 10mM DMSO","ALK,Autophagy,c-Met,ROS1","Protein Tyrosine Kinase","Crizotinib (PF-02341066) hydrochloride (Xalkori) inhibits tyrosine phosphorylation of c-Met and nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) with IC50 of of 11 nM and 24 nM in cell-based assays, respectively. Crizotinib hydrochloride is also a potent ROS1 inhibitor with Ki less than 0.025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines.",{"v":486.8,"d":"486.80"},"1415560-69-8",{"v":97,"d":"97.00"},199.26,{"v":97,"d":"97.00"},199.26,"http://www.selleckchem.com/products/crizotinib-hydrochloride.html","C21H23Cl3FN5O","Hydrochloride","Xalkori, PF-02341066 hydrochloride","Cl.CC(OC1=C(N)N=CC(=C1)C2=C[N](N=C2)C3CCNCC3)C4=C(Cl)C=CC(=C4Cl)F",4.075,3,2,5]
["S5195","Rucaparib Camsylate","g3","L8000-20","in 10mM DMSO","PARP","DNA Damage/DNA Repair","Rucaparib (Rubraca, AG014699, PF01367338) Camsylate is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains.",555.66,"1859053-21-6",{"v":100,"d":"100.00"},179.97,"<1","N/A","http://www.selleckchem.com/products/rucaparib-camsylate.html","C29H34FN3O5S","Camsylate","Rubraca, AG014699 Camsylate, PF01367338 Camsylate","CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=C3C(=CC(=C4)F)[NH]2.CC5(C)C6CCC5(C[S](O)(=O)=O)C(=O)C6",3.888,2,3,5]
["S5738","Megestrol","h3","L8000-20","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Megestrol, a synthetic progestin, is approved for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with an acquired immunodeficiency syndrome diagnosis. Megestrol acetate (Megace) is one of the first progestational agents to be evaluated for use in the hormonal therapy of advanced breast cancer.",342.47,"3562-63-8",{"v":68,"d":"68.00"},198.56,"<1","N/A","http://www.selleckchem.com/products/megestrol.html","C22H30O3","Free Base","Megace","CC(=O)C1(O)CCC2C3C=C(C)C4=CC(=O)CCC4(C)C3CCC12C",3.126,2,0,1]
["S5860","Larotrectinib","b4","L8000-20","in 10mM DMSO","Trk receptor","Protein Tyrosine Kinase","Larotrectinib (Vitrakvi, LOXO-101, ARRY-470) is an ATP-competitive, oral administered and highly selective inhibitor of the tropomyosin-related kinase (TRK) family receptors.",428.44,"1223403-58-4",{"v":86,"d":"86.00"},200.73,"<1","N/A","http://www.selleckchem.com/products/larotrectinib.html","C21H22F2N6O2","Free Base","Vitrakvi, LOXO-101, ARRY-470","OC1CCN(C1)C(=O)NC2=C3N=C(C=C[N]3N=C2)N4CCCC4C5=CC(=CC=C5F)F",1.981,3,2,3]
["S5958","Metformin","c4","L8000-20","in 10mM DMSO","AMPK,Apoptosis related,JNK,Mitophagy,p38 MAPK","PI3K/Akt/mTOR","Metformin (1,1-Dimethylbiguanide), a widely used drug for treatment of type 2 diabetes, activates AMP-activated protein kinase (AMPK) in hepatocytes. Metformin promotes mitophagy in mononuclear cells. Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153.",129.16,"657-24-9",{"v":26,"d":"26.00"},{"v":201.3,"d":"201.30"},{"v":26,"d":"26.00"},{"v":201.3,"d":"201.30"},"http://www.selleckchem.com/products/metformin.html","C4H11N5","Free Base","1,1-Dimethylbiguanide","CN(C)C(=N)NC(N)=N",-0.742,0,2,3]
["S5971","Pemetrexed","d4","L8000-20","in 10mM DMSO","Apoptosis related,Autophagy,DHFR,DNA/RNA Synthesis,Thymidylate Synthase","Apoptosis","Pemetrexed (LY231514, Alimta) is a novel antifolate and antimetabolite for thymidylate synthase (TS), dihydrofolate reductase (DHFR) and glycinamide ribonucleotide formyltransferase (GARFT) with Ki of 1.3 nM, 7.2 nM and 65 nM in cell-free assays, respectively. Pemetrexed induces autophagy and apoptosis.",427.41,"137281-23-3",{"v":85,"d":"85.00"},198.87,"<1","N/A","http://www.selleckchem.com/products/pemetrexed.html","C20H21N5O6","Free Base","LY231514, Alimta","NC1=NC(=O)C2=C([NH]C=C2CCC3=CC=C(C=C3)C(=O)NC(CCC(O)=O)C(O)=O)N1",1.144,5,4,9]
["S8932","Remdesivir (GS-5734)","e4","L8000-20","in 10mM DMSO","Antiviral,COVID-19,DNA/RNA Synthesis","Microbiology","Remdesivir (GS-5734), a monophosphoramidate prodrug of an adenosine analog, is an investigational broad-spectrum antiviral agent with in vitro activity against multiple RNA viruses, including Ebola and CoV.",602.58,"1809249-37-3",{"v":100,"d":"100.00"},165.95,"<1","N/A","http://www.selleckchem.com/products/remdesivir.html","C27H35N6O8P","Free Base","N/A","CCC(CC)COC(=O)C(C)N[P](=O)(OCC1OC(C#N)(C(O)C1O)C2=CC=C3[N]2N=CN=C3N)OC4=CC=CC=C4",2.174,7,4,14]
["S9783","6-Aminonicotinamide","f4","L8000-20","in 10mM DMSO","Dehydrogenase","Metabolism","6-Aminonicotinamide (6AN) is an antimetabolite used to inhibit the NADPH-producing pentose phosphate pathway (PPP) in many cellular systems, making them more susceptible to oxidative stress. 6-Aminonicotinamide is a competitive inhibitor of NADP+-dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) with Ki of 0.46 μM.",137.14,"329-89-5",{"v":27,"d":"27.00"},196.88,"<1","N/A","http://www.selleckchem.com/products/6-aminonicotinamide.html","C6H7N3O","Free Base","6AN","NC(=O)C1=CC=C(N)N=C1",-0.526,2,2,1]
["S2089","Fenoldopam","g4","L8000-20","in 10mM DMSO","Dopamine Receptor","Neuronal Signaling","Fenoldopam (SKF 82526) is a selective dopamine-1 (DA1) receptor agonist with natriuretic/diuretic properties with EC50 of 55.5 nM in stimulating cAMP accumulation in LLC-PK1 cells, which is more potent than DA .",305.76,"67227-56-9",{"v":77,"d":"77.00"},251.83,{"v":10,"d":"10.00"},32.71,"http://www.selleckchem.com/products/fenoldopam-corlopam.html","C16H16ClNO3","free base","SKF 82526","OC1=CC=C(C=C1)C2CNCCC3=C(Cl)C(=C(O)C=C23)O",3.053,0,4,1]
["S9973","Flumatinib (HH-GV-678)","h4","L8000-20","in 10mM DMSO","Bcr-Abl,c-Kit,PDGFR","Angiogenesis","Flumatinib (HH-GV-678) is a novel inhibitor of Bcr-Abl with IC50 values of 1.2  nM, 307.6  nM and 665.5  nM for c-Abl, PDGFRβand c-Kit, respectively.",562.59,"895519-90-1",{"v":100,"d":"100.00"},177.75,"<1","N/A","http://www.selleckchem.com/products/flumatinib-hh-gv-678.html","C29H29F3N8O","free base","HH-GV678","CN1CCN(CC1)CC2=CC=C(C=C2C(F)(F)F)C(=O)NC3=CN=C(C)C(=C3)NC4=NC(=CC=N4)C5=CN=CC=C5",3.808,5,2,8]
["E0190","Invert sugar","a5","L8000-20","in 10mM DMSO","Others","Others","Invert Sugar is a popular sweetener.",360.31,"8013-17-0","The physical form of the compound is liquid, which can be dissolved in any proportion","The physical form of the compound is liquid, which can be dissolved in any proportion","N/A","N/A","http://www.selleckchem.com/products/invert-sugar.html","C12H24O12","free base","N/A","OCC(O)C(O)C(O)C(O)C=O.OCC(O)C(O)C(O)C(=O)CO",-5.664,2,10,10]
["E0245","Rhamnose","b5","L8000-20","in 10mM DMSO","Others","Others","Rhamnose(L-Rhamnose) is an important 6-deoxy sugar present in many natural products, glycoproteins, and structural polysaccharides.",164.16,"3615-41-6",{"v":33,"d":"33.00"},201.02,{"v":-1,"d":"-1.00"},-6.09,"http://www.selleckchem.com/products/rhamnose.html","C6H12O5","free base","L-Rhamnose","CC(O)C(O)C(O)C(O)C=O",-1.903,1,4,4]
["E0527","Norgestimate","d5","L8000-20","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity.",{"v":369.5,"d":"369.50"},"35189-28-7",{"v":74,"d":"74.00"},200.27,"<1","N/A","http://www.selleckchem.com/products/norgestimate.html","C23H31NO3","free base","N/A","CCC12CCC3C(CCC4=C/C(CCC34)=N/O)C1CCC2(OC(C)=O)C#C",5.218,3,0,3]
["E0528","Flecainide","e5","L8000-20","in 10mM DMSO","Others","Neuronal Signaling","Flecainide is a common medication used to help restore and maintain sinus rhythm in patients with atrial fibrillation.",414.34,"54143-55-4",{"v":83,"d":"83.00"},200.32,"<1","N/A","http://www.selleckchem.com/products/flecainide.html","C17H20F6N2O3","free base","N/A","FC(F)(F)COC1=CC=C(OCC(F)(F)F)C(=C1)C(=O)NCC2CCCCN2",3.568,3,2,9]
["E0530","Prednicarbate","f5","L8000-20","in 10mM DMSO","Others","Endocrinology & Hormones","Prednicarbate (Dermatop) is a medium potency topical corticosteroid used to manage pruritus and inflammation associated with responsive skin conditions.",488.57,"73771-04-7",{"v":98,"d":"98.00"},200.59,"<1","N/A","http://www.selleckchem.com/products/prednicarbate.html","C27H36O8","free base","Dermatop","CCOC(=O)OC1(CCC2C3CCC4=CC(=O)C=CC4(C)C3C(O)CC12C)C(=O)COC(=O)CC",3.677,7,1,9]
["E0609","Methyl methanesulfonate","g5","L8000-20","in 10mM DMSO","DNA alkylator","DNA Damage/DNA Repair","Methyl methanesulfonate (MMS), a DNA alkylating agent, modifies both guanine (to 7-methylguanine) and adenine (to 3-methlyladenine) to cause base mispairing and replication blocks, respectively.",110.13,"66-27-3","The physical form of the compound is liquid, which can be dissolved in any proportion","The physical form of the compound is liquid, which can be dissolved in any proportion","N/A","N/A","http://www.selleckchem.com/products/methyl-methanesulfonate.html","C2H6O3S","free base","MMS","CO[S](C)(=O)=O",-0.375,1,0,1]
["E0650","γ-Terpinene","h5","L8000-20","in 10mM DMSO","Antioxidant","Apoptosis","γ-Terpinene (γ-TPN), a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly.,",136.23,"99-85-4","The physical form of the compound is liquid, which can be dissolved in any proportion","The physical form of the compound is liquid, which can be dissolved in any proportion","N/A","N/A","http://www.selleckchem.com/products/gamma-terpinen.html","C10H16","free base","γ-TPN","CC(C)C1=CCC(=CC1)C",3.448,0,0,1]
["E0704","Esaxerenone (CS-3150)","a6","L8000-20","in 10mM DMSO","Mineralocorticoid Receptor","Endocrinology & Hormones","Esaxerenone (CS-3150), a selective nonsteroidal mineralocorticoid receptor (MR) antagonist, binds to mineralocorticoid receptor and inhibits (3)H-aldosterone binding to mineralocorticoid receptor with an IC50 value of 9.4 nM. Esaxerenone (CS-3150) also has the property of increasing the likelihood of albuminuria returning to normal levels and reducing progression of albuminuria to higher levels.",466.48,"1632006-28-0",{"v":93,"d":"93.00"},199.37,{"v":-1,"d":"-1.00"},-2.14,"http://www.selleckchem.com/products/esaxerenone.html","C22H21F3N2O4S","free base","N/A","CC1=C([N](CCO)C=C1C(=O)NC2=CC=C(C=C2)[S](C)(=O)=O)C3=CC=CC=C3C(F)(F)F",4.139,3,2,7]
["E0707","Nomegestrol Acetate","b6","L8000-20","in 10mM DMSO","Estrogen/progestogen Receptor","Endocrinology & Hormones","Nomegestrol Acetate is a potent, highly selective progestogen, which is characterized as a full agonist at the progesterone receptor, with no or minimal binding to other steroid receptors, including the androgen and glucocorticoid receptors.",370.48,"58652-20-3",{"v":74,"d":"74.00"},199.74,"<1","N/A","http://www.selleckchem.com/products/nomegestrol-acetate.html","C23H30O4","free base","N/A","CC(=O)OC1(CCC2C3C=C(C)C4=CC(=O)CCC4C3CCC12C)C(C)=O",3.299,4,0,3]
["E0814","Masitinib mesylate","c6","L8000-20","in 10mM DMSO","c-Kit,FAK,FGFR,PDGFR,Src","Protein Tyrosine Kinase","Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit with IC50 of 200 nM for human recombinant c-Kit, also inhibits PDGFRα/β with IC50s of 540/800 nM, Lyn with IC50 of 510 nM for LynB, and, to a lesser extent, FGFR3 and FAK.",594.75,"1048007-93-7",{"v":100,"d":"100.00"},168.14,{"v":100,"d":"100.00"},168.14,"https://www.selleckchem.com/products/masitinib-mesylate.html","C28H30N6OS.CH4O3S","Mesylate","AB-1010 mesylate","CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC=C(C)C(=C3)NC4=NC(=CS4)C5=CN=CC=C5.C[S](O)(=O)=O",4.795,3,2,7]
["E2516","Doxorubicin","e6","L8000-20","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Adriamycin (Doxorubicin, Hydroxydaunorubicin), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent, inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DNA replication, and induces apoptosis, also inhibits human DNA topoisomerase I with an IC50 of 0.8 μM.",543.52,"23214-92-8",{"v":100,"d":"100.00"},183.99,{"v":50,"d":"50.00"},91.99,"http://www.selleckchem.com/products/doxorubicin.html","C27H29NO11","free base","Adriamycin,Hydroxydaunorubicin","COC1=C2C(=O)C3=C(C(=C4CC(O)(CC(OC5CC(N)C(O)C(C)O5)C4=C3O)C(=O)CO)O)C(=O)C2=CC=C1",-0.044,6,5,5]
["P1110","Etelcalcetide HCl","f6","L8000-20","in 10mM DMSO","CaSR","GPCR & G Protein","Etelcalcetide HCl (AMG 416) is a novel synthetic peptide agonist of the calcium-sensing receptor (CaSR) composed of a linear chain of seven d-amino acids with a d-cysteine linked to an l-cysteine via a disulfide bond.",1084.71,"1334237-71-6",{"v":100,"d":"100.00"},92.19,{"v":100,"d":"100.00"},92.19,"http://www.selleckchem.com/products/etelcalcetide-hcl.html","C38H74ClN21O10S2","hydrochloride","AMG 416","Cl.CC(NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(C)NC(=O)C(CC(S)C(N)(S)C(O)=O)NC(C)=O)C(=O)NC(CCCN=C(N)N)C(N)=O",-9.149,13,17,34]
["S1469","Calcifediol","h6","L8000-20","in 10mM DMSO","Vitamin","Metabolism","Calcifediol (Calcidiol, Didrogyl, Hidroferol, 25-hydroxyvitamin D3, 25-Hydroxycholecalciferol) is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It also suppresses PTH secretion and mRNA (ED50=2 nM).",400.64,"19356-17-3",{"v":80,"d":"80.00"},199.68,"<1","N/A","http://www.selleckchem.com/products/Calcifediol.html","C27H44O2","free base","Calcidiol, Didrogyl, Hidroferol, 25-hydroxyvitamin D3, 25-Hydroxycholecalciferol","CC(CCCC(C)(C)O)C1CCC2/C(CCCC12C)=C/C=C3/CC(O)CCC3=C",6.404,0,1,6]
["S7048","Talazoparib (BMN 673)","a7","L8000-20","in 10mM DMSO","PARP","DNA Damage/DNA Repair","Talazoparib (BMN 673, LT-673) is a novel PARP inhibitor with IC50 of 0.57 nM for PARP1 in a cell-free assay. It is also a potent inhibitor of PARP-2, but does not inhibit PARG and is highly sensitive to PTEN mutation. Phase 3.",380.35,"1207456-01-6",{"v":38,"d":"38.00"},99.91,"<1","N/A","http://www.selleckchem.com/products/bmn-673.html","C19H14F2N6O","free base","LT-673","C[N]1N=CN=C1C2C(NC3=CC(=CC4=C3C2=NNC4=O)F)C5=CC=C(F)C=C5",2.467,4,2,2]
["S7108","Encorafenib (LGX818)","b7","L8000-20","in 10mM DMSO","Raf","MAPK","Encorafenib (LGX818) is a highly potent RAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing B-RAF(V600E) with EC50 of 4 nM. Phase 3.",540.01,"1269440-17-6",{"v":100,"d":"100.00"},185.18,"<1","N/A","http://www.selleckchem.com/products/lgx818.html","C22 H27 Cl F N7 O4 S","free base","N/A","COC(=O)NC(C)CNC1=NC=CC(=N1)C2=C[N](N=C2C3=C(F)C(=CC(=C3)Cl)N[S;v6](C)(=O)=O)C(C)C",3.645,7,3,10]
["S8162","Upadacitinib (ABT-494)","c7","L8000-20","in 10mM DMSO","JAK","JAK/STAT","Upadacitinib (ABT-494) is a selective JAK1 inhibitor which demonstrates activity against JAK1 (0.045 μM) and JAK2 (0.109 μM),  with > 40 fold selectivity over JAK3 (2.1 μM) and 100 fold selectivity over TYK2 (4.7 μM) as compared to JAK1.",380.37,"1310726-60-3",{"v":76,"d":"76.00"},199.81,"<1","N/A","http://www.selleckchem.com/products/upadacitinib.html","C17H19F3N6O","free base","N/A","CCC1CN(CC1C2=CN=C3C=NC4=C(C=C[NH]4)[N]23)C(=O)NCC(F)(F)F",1.967,3,2,4]
["S8553","Avapritinib (BLU-285)","d7","L8000-20","in 10mM DMSO","c-Kit,PDGFR","Protein Tyrosine Kinase","Avapritinib (BLU-285) is a small molecule kinase inhibitor that potently inhibits PDGFRα D842V mutant activity in vitro (IC50 = 0.5 nM) and PDGFRα D842V autophosphorylation in the cellular setting (IC50 = 30 nM); also a potent inhibitor of the analogous Kit (c-Kit) mutation, D816V in Kit (c-Kit) Exon 17 (IC50 = 0.5 nM).",498.56,"1703793-34-3",{"v":66,"d":"66.00"},132.38,"<1","N/A","http://www.selleckchem.com/products/blu-285.html","C26H27FN10","free base","N/A","C[N]1C=C(C=N1)C2=C[N]3N=CN=C(N4CCN(CC4)C5=NC=C(C=N5)C(C)(N)C6=CC=C(F)C=C6)C3=C2",2.799,5,1,5]
["S1217","Cyclophosphamide","f7","L8000-20","in 10mM DMSO","DNA/RNA Synthesis","DNA Damage/DNA Repair","Cyclophosphamide(NSC 26271,Endoxan, Cytoxan, Neosar, Procytox, Revimmune, Cytophosphane) is a nitrogen mustard alkylating agent from the oxazophorines group.",261.09,"50-18-0",{"v":52,"d":"52.00"},199.17,{"v":43,"d":"43.00"},164.69,"http://www.selleckchem.com/products/Clafen.html","C7H15Cl2N2O2P","Free base","NSC 26271,Endoxan, Cytoxan, Neosar, Procytox, Revimmune, Cytophosphane","ClCCN(CCCl)[P]1(=O)NCCCO1",0.144,2,1,5]
["S2221","Apatinib (YN968D1) mesylate","g7","L8000-20","in 10mM DMSO","VEGFR","Protein Tyrosine Kinase","Apatinib mesylate (YN968D1, Rivoceranib) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib mesylate induces both autophagy and apoptosis.",493.58,"1218779-75-9",{"v":22,"d":"22.00"},44.57,"<1","N/A","http://www.selleckchem.com/products/Apatinib-YN968D1.html","C25H27N5O4S","Mesylate","YN968D1, Rivoceranib","C[S](O)(=O)=O.O=C(NC1=CC=C(C=C1)C2(CCCC2)C#N)C3=CC=CN=C3NCC4=CC=NC=C4",3.164,3,2,6]
["S2345","Podophyllotoxin (Podofilox)","h7","L8000-20","in 10mM DMSO","5-alpha Reductase","Angiogenesis","Podophyllotoxin (Condylox,Podofilox) is a lignan (lignans) found in podophyllin resin from the roots of podophyllum plants.",414.41,"518-28-5",{"v":83,"d":"83.00"},200.28,"<1","N/A","http://www.selleckchem.com/products/Podophyllotoxin(Podofilox).html","C22H22O8","Free base","Condylox,Podofilox","COC1=C(OC)C(=CC(=C1)C2C3C(COC3=O)C(O)C4=CC5=C(OCO5)C=C24)OC",2.111,7,1,4]
["S3020","Romidepsin","a8","L8000-20","in 10mM DMSO","Apoptosis related,HDAC","Cytoskeletal Signaling","Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM in cell-free assays, respectively. Romidepsin (FK228/depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cells.",{"v":540.7,"d":"540.70"},"128517-07-7",{"v":10,"d":"10.00"},18.49,"<1","N/A","http://www.selleckchem.com/products/Romidepsin-FK228.html","C24H36N4O6S2","Free base","FK228, Depsipeptide, FR 901228, NSC 630176,","C\\C=C1/NC(=O)C2CSSCC/C=C/C(CC(=O)NC(C(C)C)C(=O)N2)OC(=O)C(NC1=O)C(C)C",1.689,6,4,2]
["S6594","Liarozole dihydrochloride","b8","L8000-20","in 10mM DMSO","P450 (e.g. CYP17)","Metabolism","Liarozole Dihydrochloride is identified as a modest inhibitor of P450 with IC50 of 2.2–6.0 μM and 260 nM for CYP26 and rat CYP17 respectively.",381.69,"1883548-96-6",{"v":76,"d":"76.00"},199.11,{"v":76,"d":"76.00"},199.11,"http://www.selleckchem.com/products/liarozole-dihydrochloride.html","C₁₇H₁₅Cl₃N₄","Dihydrochloride","N/A","Cl.Cl.ClC1=CC=CC(=C1)C([N]2C=CN=C2)C3=CC4=C(C=C3)N=C[NH]4",4.062,2,1,3]
["S6984","Dianhydrogalactitol (VAL-083)","c8","L8000-20","in 10mM DMSO","DNA alkylator","DNA Damage/DNA Repair","Dianhydrogalactitol (VAL-083, Dianhydrodulcitol, Dulcitol Diepoxide) is a bi-functional alkylating agent that readily crosses the blood-brain barrier and creates N7 methylation on DNA. Dianhydrogalactitol shows antitumor activity.",146.14,"23261-20-3",{"v":29,"d":"29.00"},198.44,{"v":29,"d":"29.00"},198.44,"http://www.selleckchem.com/products/dianhydrogalactitol-val-083.html","C6H10O4","Free base","Dianhydrodulcitol, Dulcitol Diepoxide","OC(C(O)C1CO1)C2CO2",-1.408,2,2,3]
["S7930","Ixabepilone (BMS-247550)","d8","L8000-20","in 10mM DMSO","Microtubule Associated","Cytoskeletal Signaling","Ixabepilone (Azaepothilone B, BMS-247550, Ixempra, Aza-epothilone B) is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis.",{"v":506.7,"d":"506.70"},"219989-84-1",{"v":100,"d":"100.00"},197.36,"<1","N/A","http://www.selleckchem.com/products/ixabepilone-bms-247550.html","C27H42N2O5S","Free base","Azaepothilone B, BMS-247550, Ixempra, Aza-epothilone B","CC1CCCC2(C)OC2CC(NC(=O)CC(O)C(C)(C)C(=O)C(C)C1O)C(/C)=C/C3=CSC(=N3)C",3.132,4,3,2]
["S8064","Midostaurin (PKC412)","e8","L8000-20","in 10mM DMSO","PKC","Cytoskeletal Signaling","Midostaurin (pkc412, CGP 41251) is a multi-targeted kinase inhibitor, including PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50 ranging from 80-500 nM.",570.64,"120685-11-2",{"v":100,"d":"100.00"},175.24,"<1","N/A","http://www.selleckchem.com/products/midostaurin-pkc412.html","C35H30N4O4","Free base","CGP 41251","COC1C(CC2OC1(C)[N]3C4=C(C=CC=C4)C5=C3C6=C(C7=C(C=CC=C7)[N]26)C8=C5CNC8=O)N(C)C(=O)C9=CC=CC=C9",5.279,4,1,3]
["S8716","Pralsetinib (BLU-667)","f8","L8000-20","in 10mM DMSO","c-RET","Apoptosis","Pralsetinib (BLU-667, CS 3009, Gavreto) is a highly potent and selective RET (c-RET) inhibitor with an IC50 of 0.4 nM for WT RET. It also demonstrates potent activity (IC50 0.4 nmol/L) against common oncogenic RET alterations, including RET (M918T).",{"v":533.6,"d":"533.60"},"2097132-94-8",{"v":100,"d":"100.00"},187.41,"<1","N/A","http://www.selleckchem.com/products/blu-667.html","C27H32FN9O2","Free base","CS 3009, Gavreto","COC1(CCC(CC1)C2=NC(=CC(=N2)NC3=N[NH]C(=C3)C)C)C(=O)NC(C)C4=CN=C(C=C4)[N]5C=C(F)C=N5",3.716,7,3,8]
["S8830","Sotorasib (AMG510)","g8","L8000-20","in 10mM DMSO","Ras","Cell Cycle","Sotorasib (AMG510) is a potent KRAS G12C covalent inhibitor with potential antineoplastic activity.This AMG510 is a chiral compound.",560.59,"2296729-00-3",{"v":100,"d":"100.00"},178.38,"<1","N/A","http://www.selleckchem.com/products/amg510.html","C30H30F2N6O3","Free base","N/A","CC(C)C1=C(N2C(=O)N=C(N3CCN(CC3C)C(=O)C=C)C4=CC(=C(N=C24)C5=C(F)C=CC=C5O)F)C(=CC=N1)C",5.357,5,1,5]
["S8926","Valemetostat (DS-3201)","h8","L8000-20","in 10mM DMSO","EZH1/2","Methylation","Valemetostat (DS-3201, DS-3201b) is a selective EZH1/2 dual inhibitor.",488.02,"1809336-39-7",{"v":100,"d":"100.00"},204.91,"<1","N/A","http://www.selleckchem.com/products/valemetostat-ds-3201.html","C26H34ClN3O4","Free base","DS-3201b","CN(C)C1CCC(CC1)C2(C)OC3=C(Cl)C=C(C(=O)NCC4=C(C)C=C(C)NC4=O)C(=C3O2)C",3.963,4,2,5]
["S8942","Suramin sodium salt","a9","L8000-20","in 10mM DMSO","DNA/RNA Synthesis,Sirtuin,Topoisomerase","Metabolism","Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatase (PTPases) inhibitor, also is the potent inhibitor of sirtuins, purified topoisomerase II and SARS-CoV-2 RNA-dependent RNA polymerase (RdRp).",1435.23,"129-46-4",{"v":100,"d":"100.00"},69.68,{"v":100,"d":"100.00"},69.68,"http://www.selleckchem.com/products/suramin-sodium-salt.html","C51H40N6O23S6.6Na","Sodium salt","Suramin hexasodium salt","CC1=C(NC(=O)C2=CC(=CC=C2)NC(=O)NC3=CC(=CC=C3)C(=O)NC4=CC(=CC=C4C)C(=O)NC5=CC=C(C6=C5C(=CC(=C6)[S;v6](=O)(=O)O[Na])[S;v6](=O)(=O)O[Na])[S;v6](=O)(=O)O[Na])C=C(C=C1)C(=O)NC7=CC=C(C8=C7C(=CC(=C8)[S;v6](=O)(=O)O[Na])[S;v6](=O)(=O)O[Na])[S;v6](=O)(=O)O[Na]",4.993,11,6,22]
["S8955","Sotorasib (AMG510) racemate","b9","L8000-20","in 10mM DMSO","Ras","Cell Cycle","Sotorasib (AMG510) racemate is a racemic of AMG-510 which is a potent KRAS G12C covalent inhibitor with potential antineoplastic activity.",560.59,"2252403-56-6",{"v":100,"d":"100.00"},178.38,"<1","N/A","http://www.selleckchem.com/products/amg-510-racemate.html","C30H30F2N6O3","Free base","N/A","CC(C)C1=C(N2C(=O)N=C(N3CCN(CC3C)C(=O)C=C)C4=CC(=C(N=C24)C5=C(F)C=CC=C5O)F)C(=CC=N1)C",5.357,5,1,5]
["S8999","Exatecan Mesylate","c9","L8000-20","in 10mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Exatecan Mesylate (DX-8951f) is a water-soluble and non-pro-drug analog of camptothecin and shows significant topoisomerase I inhibition with IC50 of 0.975 μg/ml.",531.55,"169869-90-3",{"v":12.5,"d":"12.50"},23.52,{"v":12.5,"d":"12.50"},23.52,"http://www.selleckchem.com/products/exatecan-mesylate.html","C24H22FN3O4.CH4O3S","Mesylate","DX-8951 Mesylate","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C5C(N)CCC6=C5C(=CC(=C6C)F)N=C34)C2=O.C[S](O)(=O)=O",1.689,4,1,1]
["S9522","Valrubicin","d9","L8000-20","in 10mM DMSO","PKC","TGF-beta/Smad","Valrubicin(AD-32) is a chemotherapy drug used to treat bladder cancer. Valrubicin is a chemotherapy agent, inhibits TPA- and PDBu-induced PKC activation with IC50s of 0.85 and 1.25 μM, respectively.",723.64,"56124-62-0",{"v":100,"d":"100.00"},138.19,"<1","N/A","http://www.selleckchem.com/products/valrubicin.html","C34H36F3NO13","Free base","AD-32","CCCCC(=O)OCC(=O)C1(O)CC(OC2CC(NC(=O)C(F)(F)F)C(O)C(C)O2)C3=C(C1)C(=C4C(=O)C5=C(C(=O)C4=C3O)C(=CC=C5)OC)O",3.024,9,4,12]
["S9702","Finerenone","e9","L8000-20","in 10mM DMSO","Mineralocorticoid Receptor","Endocrinology & Hormones","Finerenone (FIN, BAY 94-8862) is a highly selective and orally available nonsteroidal antagonist of mineralocorticoid receptor (MR) with IC50 of 18 nM. Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.",378.42,"1050477-31-0",{"v":76,"d":"76.00"},200.84,"<1","N/A","http://www.selleckchem.com/products/finerenone.html","C21H22N4O3","Free base","FIN, BAY 94-8862","CCOC1=NC=C(C)C2=C1C(C3=CC=C(C=C3OC)C#N)C(=C(C)N2)C(N)=O",2.613,4,2,5]
["S9726","Rimiducid (AP1903)","f9","L8000-20","in 10mM DMSO","FKBP","Apoptosis","Rimiducid (AP1903) is a chemical protein dimerizer and binds tightly to the target FKBP fusion protein while binding minimally to the abundant natural FKBP. Rimiducid elicites potent and dose-dependent apoptosis of cells in culture expressing dimerizer-dependent Fas constructs, with an EC50 of ≈0.1 nM.",1411.63,"195514-63-7",{"v":100,"d":"100.00"},70.84,"<1","N/A","http://www.selleckchem.com/products/rimiducid-ap1903.html","C78H98N4O20","Free base","N/A","CCC(C(=O)N1CCCCC1C(=O)OC(CCC2=CC(=C(OC)C=C2)OC)C3=CC(=CC=C3)OCC(=O)NCCNC(=O)COC4=CC=CC(=C4)C(CCC5=CC(=C(OC)C=C5)OC)OC(=O)C6CCCCN6C(=O)C(CC)C7=CC(=C(OC)C(=C7)OC)OC)C8=CC(=C(OC)C(=C8)OC)OC",11.602,20,2,39]
["E0742","Melengestrol Acetate","g9","L8000-20","in 10mM DMSO","CYP450","Metabolism","Melengestrol Acetate, progestational steroid  suppress the AT3 tumour.",396.52,"2919-66-6",{"v":10,"d":"10.00"},25.22,"<1","N/A","http://www.selleckchem.com/products/melengestrol-acetate.html","C25H32O4","Acetate","N/A","CC(=O)OC1(C(C)=O)C(=C)CC2C3C=C(C)C4=CC(=O)CCC4(C)C3CCC12C",3.696,4,0,3]
["E2438","Ginsenoside Rg3","h9","L8000-20","in 10mM DMSO","Others","Others","Ginsenoside Rg3 is a ginsenoside found in Panax japonicus var. and Panax ginseng, mainly used for the study of tumor diseases.",{"v":785,"d":"785.00"},"11019-45-7",{"v":100,"d":"100.00"},127.39,"<1","N/A","http://www.selleckchem.com/products/ginsenoside-rg3.html","C42H72O13","Free base","N/A","CC(C)=CCCC(C)(O)C1CCC2(C)C1C(O)CC3C4(C)CCC(OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(C)(C)C4CCC23C",2.295,4,8,10]
["P1005","Abarelix Acetate","a10","L8000-20","in 10mM DMSO","Others","Endocrinology & Hormones","Abarelix Acetate is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer research.",1476.12,"785804-17-3",{"v":100,"d":"100.00"},67.75,{"v":100,"d":"100.00"},67.75,"http://www.selleckchem.com/peptide/abarelix-acetate.html","C74H99ClN14O16","Acetate","Ac-D-2-Nal-D-4-Cl-Phe-D-3-Pal-Ser-N-Me-Tyr-D-Asn-Leu-Lys(ipr)-Pro-D-Ala-NH2","CC(C)CC(NC(=O)C(CC(N)=O)NC(=O)C(CC1=CC=C(O)C=C1)N(C)C(=O)C(CO)NC(=O)C(CC2=CN=CC=C2)NC(=O)C(CC3=CC=C(Cl)C=C3)NC(=O)C(CC4=CC5=C(C=CC=C5)C=C4)NC(C)=O)C(=O)NC(CCCCNC(C)C)C(=O)N6CCCC6C(=O)NC(C)C(N)=O.CC(O)=O",-0.464,14,13,38]
["P1109","Linaclotide","b10","L8000-20","in 10mM DMSO","Others","Others","Linaclotide is a potent and selective guanylate cyclase C (GC-C) agonist that elicits pharmacological effects locally in the gastrointestinal tract.",1526.75,"851199-59-2",{"v":100,"d":"100.00"},{"v":65.5,"d":"65.50"},"<1","N/A","http://www.selleckchem.com/products/linaclotide.html","C59H79N15O21S6","Free base","N/A","CC(O)C1NC(=O)C2CSSCC3NC(=O)C(N)CSSCC(NC(=O)C(CSSCC(NC(=O)CNC1=O)C(=O)NC(CC4=CC=C(O)C=C4)C(O)=O)NC(=O)C(CC5=CC=C(O)C=C5)NC(=O)C(CCC(O)=O)NC3=O)C(=O)NC(CC(N)=O)C(=O)N6CCCC6C(=O)NC(C)C(=O)N2",-7.707,16,17,13]
["E0359","Evocalcet","c10","L8000-20","in 10mM DMSO","CaSR","GPCR & G Protein","Evocalcet (KHK7580) is an novel oral calcimimetic agent which acts via allosteric activation of the calcium sensing receptor (CaSR). Evocalcet (0, 20 and 60 nM) dose-dependently increases cytoplasmic  [Ca2+] concentrations  with an EC50 value of 92.7 nM in hCaR-HEK293 cells.",374.48,"870964-67-3",{"v":75,"d":"75.00"},200.28,"<1","N/A","https://www.selleckchem.com/products/evocalcet.html","C24H26N2O2","free base","KHK7580","CC(NC1CCN(C1)C2=CC=C(CC(O)=O)C=C2)C3=CC=CC4=C3C=CC=C4",1.334,1,1,6]
["E1310","DPCPX","d10","L8000-20","in 10mM DMSO","Others","Others","DPCPX (PD 116948), a xanthine derivative, is a highly potent and selective adenosine A1 receptor (ADORA1) antagonist, with a Ki of 0.46 nM.",304.39,"102146-07-6",{"v":61,"d":"61.00"},{"v":200.4,"d":"200.40"},"<1","N/A","https://www.selleckchem.com/products/dpcpx.html","C16H24N4O2","free base","PD 116948","CCCN1C(=O)N(CCC)C2=C([NH]C(=N2)C3CCCC3)C1=O",{"v":3.37,"d":"3.370"},3,1,5]
["E1410","Fluspirilene","e10","L8000-20","in 10mM DMSO","Calcium Channel","Transmembrane Transporters","Fluspirilene(R 6218; Redeptin) is a non-competitive antagonist of L-type calcium channels with an IC50 of 0.03 μM in cell-free assays. Fluspirileneis a long-acting injectable depot antipsychotic agent used for schizophrenia.",475.57,"1841-19-6",{"v":95,"d":"95.00"},199.76,"<1","N/A","https://www.selleckchem.com/products/fluspirilene.html","C29H31F2N3O","free base","R 6218, Redeptin","FC1=CC=C(C=C1)C(CCCN2CCC3(CC2)N(CNC3=O)C4=CC=CC=C4)C5=CC=C(F)C=C5",5.545,1,1,7]
["E2873","Laropiprant","f10","L8000-20","in 10mM DMSO","Prostaglandin Receptor","GPCR & G Protein","Laropiprant is a potent and selective prostaglandin D2 (DP) receptor antagonist with a Ki value of 0.57 nM.",{"v":435.9,"d":"435.90"},"571170-77-9",{"v":87,"d":"87.00"},199.59,"<1","N/A","https://www.selleckchem.com/products/laropiprant.html","C21H19CIFNO4S","free base","N/A","C[S](=O)(=O)C1=C2[N](CC3=CC=C(Cl)C=C3)C4=C(CCC4CC(O)=O)C2=CC(=C1)F",4.876,3,0,5]
["E2874","Sofpironium bromide","g10","L8000-20","in 10mM DMSO","AChR","Neuronal Signaling","Sofpironium bromide (BBI 4000) is an anticholinergic agent that reduces sweat by inhibiting  M3 muscarinic receptors  in eccrine glands.",{"v":470.4,"d":"470.40"},"1628106-94-4",{"v":94,"d":"94.00"},199.83,{"v":94,"d":"94.00"},199.83,"https://www.selleckchem.com/products/sofpironium-bromide.html","C22H32NO5.Br","bromide ","BBI 4000","[Br-].CCOC(=O)C[N+]1(C)CCC(C1)OC(=O)C(O)(C2CCCC2)C3=CC=CC=C3",-0.905,4,0,9]
["E2876","pemafibrate","h10","L8000-20","in 10mM DMSO","PPAR","Metabolism","Pemafibrate(K-877) is a selective agonist of peroxisome proliferator-activated receptor (PPAR) α with an IC50  of 10 µM.",490.55,"848259-27-8",{"v":98,"d":"98.00"},199.78,"<1","N/A","https://www.selleckchem.com/products/pemafibrate.html","C28H30N2O6","free base","K-877","CCC(OC1=CC=CC(=C1)CN(CCCOC2=CC=C(OC)C=C2)C3=NC4=CC=CC=C4O3)C(O)=O",5.794,6,0,13]
["E2944","Norepinephrine hydrochloride","a11","L8000-20","in 10mM DMSO","Adrenergic Receptor","GPCR & G Protein","Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent agonist of adrenergic receptor (AR). Norepinephrine activates α1, α2, β1 receptors.",205.64,"329-56-6",{"v":41,"d":"41.00"},199.38,{"v":41,"d":"41.00"},199.38,"https://www.selleckchem.com/products/norepinephrine-hydrochloride.html","C8H11NO3.ClH","hydrochloride","Levarterenol; L-Noradrenaline","Cl.NCC(O)C1=CC(=C(O)C=C1)O",0.323,0,4,2]
["E4010","L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride","b11","L8000-20","in 10mM DMSO","Others","Others","L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride(Melevodopa hydrochloride) is a precursor to L-DOPA. It is an antiparkinsonian agent L-DOPA methyl ester that  elicits antitumor functionality in leukemia and melanoma.",247.68,"1421-65-4",{"v":50,"d":"50.00"},201.87,{"v":50,"d":"50.00"},201.87,"https://www.selleckchem.com/products/l-3,4-dihydroxyphenylalanine-methyl-ester-hydrochloride.html","C10H13NO4.ClH","hydrochloride","Melevodopa hydrochloride","Cl.COC(=O)C(N)CC1=CC(=C(O)C=C1)O",0.997,2,3,4]
["S9865","CB-5339","c11","L8000-20","in 10mM DMSO","p97","Ubiquitin","CB-5339 is a potent p97/Valosin Containing Protein (VCP) inhibitor with an IC50 of 9 nM.",412.49,"1863952-15-1",{"v":100,"d":"100.00"},242.43,"<1","N/A","https://www.selleckchem.com/products/cb-5339.html","C24H24N6O","free base","N/A","CC1=CC2=C(C=CC=C2[N]1C3=NC(=C4CCCN=C4N3)NCC5=CC=CC=C5)C(N)=O",3.683,3,3,5]
["E4467","Temozolomide Acid","d11","L8000-20","in 10mM DMSO","Others","Others","Temozolomide acid is a carboxylic acid derivative of Temozolomide. It has an anticancer activity by causing breaks in DNA double strand, cell cycle arrest, and eventually cell death.",195.14,"113942-30-6",{"v":39,"d":"39.00"},199.86,"<1","N/A","https://www.selleckchem.com/products/temozolomide-acid.html","C6H5N5O3","free base","N/A","CN1N=NC2=C(N=C[N]2C1=O)C(O)=O",0.679,5,0,1]
["E4474","Infigratinib Phosphate","e11","L8000-20","in 10mM DMSO","FGFR","Angiogenesis","Infigratinib Phosphate (NVP-BGJ398 phosphate) is the phosphate salt form of infigratinib, an orally bioavailable pan-inhibitor of human  fibroblast growth factor receptors (FGFRs)  with IC50 of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for  FGFR1, FGFR2, FGFR3, and FGFR4 respectively. It also has potential antiangiogenic, antineoplastic and antitumor activities.",658.47,"1310746-10-1",{"v":100,"d":"100.00"},151.87,"<1","N/A","https://www.selleckchem.com/products/infigratinib-phosphate.html","C26H31Cl2N7O3.H3O4P","Phosphate ","NVP-BGJ398 phosphate","CCN1CCN(CC1)C2=CC=C(NC3=CC(=NC=N3)N(C)C(=O)NC4=C(Cl)C(=CC(=C4Cl)OC)OC)C=C2.O[P](O)(O)=O",4.874,5,2,8]
["E1445","Palovarotene","f11","L8000-20","in 10mM DMSO","Retinoid Receptor","Metabolism","Palovarotene (R 667; Ro 3300074) is a nuclear retinoic acid receptor γ (RAR-γ) agonist. It reduces heterotopic ossification (HO) in cultures and in murine and rat fibrodysplasia ossificans progressiva (FOP) models.",414.54,"410528-02-8",{"v":83,"d":"83.00"},200.22,"<1","N/A","https://www.selleckchem.com/products/palovarotene.html","C27H30N2O2","free base","R 667, Ro 3300074","CC1(C)CCC(C)(C)C2=CC(=C(C[N]3C=CC=N3)C=C12)\\C=C\\C4=CC=C(C=C4)C(O)=O",6.108,2,0,5]
["S4684","Sildenafil","g11","L8000-20","in 10mM DMSO","PDE","Metabolism","Sildenafil (Revatio, UK-92480, Viagra) is a Phosphodiesterase 5 Inhibitor with IC50 of 5.22 nM.",474.58,"139755-83-2","N/A",">10","N/A","N/A","http://selleckchem.com/products/sildenafil.html","C22H30N6O4S","free base","Revatio, UK-92480, Viagra","CCCC1=N[N](C)C2=C1N=C(NC2=O)C3=CC(=CC=C3OCC)[S](=O)(=O)N4CCN(C)CC4",2.247,6,1,7]
["S1037","Perifosine (KRX-0401)","a2","L8000-21","in 10mM Water","Akt","PI3K/Akt/mTOR","Perifosine (KRX-0401, NSC639966, D21266) is a novel Akt inhibitor with IC50 of 4.7 μM in MM.1S cells, targets pleckstrin homology domain of Akt. Phase 3.",461.66,"157716-52-4","<1","N/A",{"v":8,"d":"8.00"},17.33,"http://selleckchem.com/products/Perifosine.html","C25H52NO4P","free base","NSC639966, D21266","CCCCCCCCCCCCCCCCCCO[P]([O-])(=O)OC1CC[N+](C)(C)CC1",4.607,2,0,20]
["S1116","Palbociclib (PD-0332991) HCl","b2","L8000-21","in 10mM Water","CDK","Cell Cycle","Palbociclib (PD-0332991) HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays, respectively. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.",483.99,"827022-32-2",{"v":3,"d":"3.00"},{"v":6.2,"d":"6.20"},{"v":30,"d":"30.00"},61.98,"http://selleckchem.com/products/PD-0332991.html","C24H29N7O2.HCl","Hydrochloride","N/A","Cl.CC(=O)C1=C(C)C2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2N(C5CCCC5)C1=O",3.183,5,2,5]
["S1135","Pemetrexed (LY-231514) disodium","c2","L8000-21","in 10mM Water","Apoptosis related,Autophagy,DHFR,DNA/RNA Synthesis,Thymidylate Synthase","Metabolism","Pemetrexed (LY-231514) disodium is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM in cell-free assays, respectively. Pemetrexed induces autophagy and apoptosis.",471.37,"150399-23-8","<1","N/A",{"v":94,"d":"94.00"},199.42,"http://selleckchem.com/products/Pemetrexed-disodium.html","C20H19N5Na2O6","Disodium salt","LY-231514 disodium","[Na+].[Na+].NC1=NC(=O)C2=C([NH]C=C2CCC3=CC=C(C=C3)C(=O)NC(CCC([O-])=O)C([O-])=O)N1",-1.804,3,4,9]
["S1149","Gemcitabine (LY-188011) HCl","d2","L8000-21","in 10mM Water","Autophagy,DNA/RNA Synthesis,Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Gemcitabine (LY-188011, NSC 613327) HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.",299.66,"122111-03-9","<1","N/A",{"v":19,"d":"19.00"},63.41,"http://selleckchem.com/products/Gemcitabine-Hydrochloride(Gemzar).html","C9H11F2N3O4.HCI","Hydrochloride","NSC 613327,LY-188011 HCl","Cl.NC1=NC(=O)N(C=C1)C2OC(CO)C(O)C2(F)F",-1.012,3,3,2]
["S1311","Pamidronate Disodium","g2","L8000-21","in 10mM Water","Others","Others","Pamidronate Disodium (CGP 23339AE) is a nitrogen containing bisphosphonate, used to prevent osteoporosis.",279.03,"57248-88-1","<1","N/A",{"v":56,"d":"56.00"},{"v":200.7,"d":"200.70"},"http://selleckchem.com/products/Pamidronate-Disodium.html","C3H9NNa2O7P2","Disodium salt","CGP 23339AE","[Na+].[Na+].NCCC(O)([P](O)([O-])=O)[P](O)([O-])=O",-5.016,0,1,4]
["S1339","Galanthamine HBr","h2","L8000-21","in 10mM Water","AChR,ADC Cytotoxin","Neuronal Signaling","Galanthamine is an AChE inhibitor with IC50 of 0.35 μM, exhibits 50-fold selectivity against butyryl-cholinesterase.",368.27,"1953-04-4","<1","N/A",{"v":36,"d":"36.00"},97.75,"http://selleckchem.com/products/Galanthamine-hydrobromide.html","C17H21NO3.HBr","Hydrobromide","N/A","Br.COC1=CC=C2CN(C)CCC34C=CC(O)CC3OC1=C24",1.933,2,1,1]
["S1345","Granisetron HCl","a3","L8000-21","in 10mM Water","5-HT Receptor","Neuronal Signaling","Granisetron is a serotonin 5-HT3 receptor antagonist,used to treat chemotherapy-induced nausea and vomiting.",348.87,"107007-99-8",{"v":1,"d":"1.00"},2.87,{"v":69,"d":"69.00"},197.78,"http://selleckchem.com/products/Granisetron-Hydrochloride.html","C18H24N4O.HCl","Hydrochloride","N/A","Cl.CN1C2CCCC1CC(C2)NC(=O)C3=N[N](C)C4=CC=CC=C34",2.783,2,1,2]
["S1375","Dorzolamide HCl","b3","L8000-21","in 10mM Water","Carbonic Anhydrase","Metabolism","Dorzolamide (MK-507, L-671152) HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent.",{"v":360.9,"d":"360.90"},"130693-82-2","<1","N/A",{"v":14,"d":"14.00"},38.79,"http://selleckchem.com/products/Dorzolamide-HCL.html","C10H16N2O4S3.HCl","Hydrochloride","MK-507 (L-671152) HCl","Cl.CCNC1CC(C)[S](=O)(=O)C2=C1C=C(S2)[S](N)(=O)=O",0.527,4,2,3]
["S1440","Varenicline Tartrate (CP 526555-18)","c3","L8000-21","in 10mM Water","AChR","Neuronal Signaling","Varenicline Tartrate (CP 526555-18, Chantix, Champix) is a nicotinic AChR partial agonist, used to treat nicotine addiction.",361.35,"375815-87-5",{"v":1,"d":"1.00"},2.77,{"v":72,"d":"72.00"},199.25,"http://selleckchem.com/products/Varenicline-tartrate.html","C13H13N3.C4H6O6","Tartrate","Chantix, Champix,CP 526555-18","OC(C(O)C(O)=O)C(O)=O.C1NCC2CC1C3=C2C=C4N=CC=NC4=C3",{"v":-3.33,"d":"-3.330"},4,3,3]
["S1506","Perindopril Erbumine","d3","L8000-21","in 10mM Water","RAAS","Endocrinology & Hormones","Perindopril Erbumine (S9490-3) is a pro-drug and metabolized in vivo by hydrolysis of the ester group to form Perindoprilat, the biologically active metabolite, a potent ACE inhibitor with IC50 of 1.05 nM. Perindopril Erbumine is used for in vivo studies and Perindoprilat is recommened for in vitro research.",{"v":441.6,"d":"441.60"},"107133-36-8","<1","N/A",{"v":88,"d":"88.00"},199.28,"http://selleckchem.com/products/Perindopril-Erbumine(Aceon).html","C19H32N2O5.C4H11N","t-Butylamine","S9490-3","CCCC(NC(C)C(=O)N1C2CCCCC2CC1C(O)=O)C(=O)OCC.CC(C)(C)N",0.016,4,2,9]
["S1516","Cidofovir","e3","L8000-21","in 10mM Water","CMV,DNA/RNA Synthesis","DNA Damage/DNA Repair","Cidofovir (HPMPC,Vistide,GS 0504) suppresses virus replication by selective inhibition of viral DNA synthesis.",279.19,"113852-37-2",{"v":2,"d":"2.00"},7.16,{"v":12,"d":"12.00"},42.98,"http://selleckchem.com/products/Cidofovir.html","C8H14N3O6P","Free Base","HPMPC,Vistide,GS 0504","NC1=NC(=O)N(CC(CO)OC[P](O)(O)=O)C=C1",-2.175,3,2,6]
["S1518","Ibuprofen Lysine","f3","L8000-21","in 10mM Water","COX","Neuronal Signaling","Ibuprofen Lysine is a non-steroidal anti-inflammatory drug.",352.47,"57469-77-9","<1","N/A",{"v":71,"d":"71.00"},201.44,"http://selleckchem.com/products/Ibuprofen-Lysine(Motrin).html","C19H32N2O4","Lysine","N/A","CC(C)CC1=CC=C(C=C1)C(C)C(O)=O.NCCCCC(N)C(O)=O",-2.112,2,2,9]
["S1579","Palbociclib (PD0332991) Isethionate","g3","L8000-21","in 10mM Water","CDK","Cell Cycle","Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.",573.66,"827022-33-3","<1","N/A",{"v":10,"d":"10.00"},17.43,"http://selleckchem.com/products/pd-0332991-palbociclib-isethionate.html","C24H29N7O2.C2H6O4S","Isethionate","N/A","CC(=O)C1=C(C)C2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2N(C5CCCC5)C1=O.OCC[S](O)(=O)=O",1.847,5,3,7]
["S1624","Alendronate sodium trihydrate","h3","L8000-21","in 10mM Water","Others","Metabolism","Alendronate sodium trihydrate (G-704650, MK-217), a nitrogen-containing bisphosphonate, is a potent inhibitor of bone resorption used for the treatment and prevention of osteoporosis.",326.13,"121268-17-5","<1","N/A",{"v":20,"d":"20.00"},61.33,"http://selleckchem.com/products/Alendronate-Sodium(Fosamax).html","C4H13NO7P2.3H2O.Na","Sodium Salt","G-704650, MK-217","O.O.O.NCCCC(O)([P](O)(O)=O)[P](O)(=O)O[Na]",{"v":0,"d":"0.000"},0,0,0]
["S1648","Cytarabine (U-19920A)","a4","L8000-21","in 10mM Water","Apoptosis related,Autophagy,DNA/RNA Synthesis,Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Cytarabine (Cytarabin, Ara-C, Arabinofuranosyl Cytidine, Cytosine β-D-arabinofuranoside, Cytosine arabinoside, NSC 63878, NSC 287459,U-19920A) is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM in wild-type CCRF-CEM cells. Cytarabine induces autophagy and apoptosis.",243.22,"147-94-4",{"v":1,"d":"1.00"},4.11,{"v":48,"d":"48.00"},197.35,"http://selleckchem.com/products/Cytarabine(Cytosar-U).html","C9H13N3O5","free base","Cytarabin,Ara-C,Arabinofuranosyl Cytidine,Cytosine β-D-arabinofuranoside,Cytosine arabinoside,NSC 63878,NSC 287459,U-19920A","NC1=NC(=O)N(C=C1)C2OC(CO)C(O)C2O",-2.396,3,4,2]
["S1853","Penicillamine","c4","L8000-21","in 10mM Water","Others","Others","Penicillamine (Dimethyl Cysteine) is used as an antirheumatic and as a chelating agent in Wilson’s disease.",149.21,"52-67-5","<1","N/A",{"v":30,"d":"30.00"},201.06,"http://selleckchem.com/products/Penicillamine(Cuprimine).html","C5H11NO2S","free base","Dimethyl Cysteine","CC(C)(S)C(N)C(O)=O",-2.496,1,1,2]
["S1857","Etidronate","d4","L8000-21","in 10mM Water","phosphatase","Metabolism","Etidronate is a non-aminobisphosphonate, show protein tyrosine phosphatase (PTP) inhibitory activity, used for the treatment of Paget's disease and the prevention of heterotopic ossification.",206.03,"2809-21-4","<1","N/A",{"v":41,"d":"41.00"},{"v":199,"d":"199.00"},"http://selleckchem.com/products/etidronate-didronel.html","C2H8O7P2","free base","N/A","CC(O)([P](O)(O)=O)[P](O)(O)=O",-0.701,0,0,2]
["S1875","Tranexamic Acid","e4","L8000-21","in 10mM Water","Others","Others","Tranexamic Acid(Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.",157.21,"1197-18-8","<1","N/A",{"v":31,"d":"31.00"},197.19,"http://selleckchem.com/products/tranexamic-acid-transamin.html","C8H15NO2","free base","Transamin","NCC1CCC(CC1)C(O)=O",-1.753,1,1,2]
["S1984","Ticlopidine HCl","f4","L8000-21","in 10mM Water","P2 Receptor","Neuronal Signaling","Ticlopidine HCl is an P2 receptor inhibitor against ADP-induced platelet aggregation with IC50 of ~2 μM.",300.25,"53885-35-1",{"v":1,"d":"1.00"},3.33,{"v":4,"d":"4.00"},13.32,"http://selleckchem.com/products/ticlopidine-hydrochloride.html","C14H14ClNS.HCl","Hydrochloride","N/A","Cl.ClC1=C(CN2CCC3=C(C2)C=CS3)C=CC=C1",4.275,0,0,2]
["S1995","Procarbazine HCl","g4","L8000-21","in 10mM Water","DNA/RNA Synthesis","DNA Damage/DNA Repair","Procarbazine HCl (NSC-77213) is a hydrochloride salt form of procarbazine which is a polyfunctional alkylating compound, used for the treatment of Hodgkin's lymphoma.",257.76,"366-70-1","<1","N/A",{"v":52,"d":"52.00"},201.74,"http://selleckchem.com/products/procarbazine-hydrochloride-matulane.html","C12H19N3O.HCl","Hydrochloride","NSC-77213 HCl","Cl.CNNCC1=CC=C(C=C1)C(=O)NC(C)C",{"v":1.12,"d":"1.120"},1,3,5]
["S1999","Sodium butyrate","h4","L8000-21","in 10mM Water","Apoptosis related,Autophagy,HDAC","Epigenetics","Sodium butyrate (NaB, Butanoic acid sodium salt), sodium salt of butyric acid, is a histone deacetylase inhibitor and competitively binds to the zinc sites of class I and II histone deacetylases (HDACs). Sodium butyrate (NaB) inhibits cell cycle progression, promotes differentiation, and induces apoptosis and autophagy in several types of cancer cells.",110.09,"156-54-7","<1","N/A",{"v":22,"d":"22.00"},199.84,"http://selleckchem.com/products/Sodium-butyrate.html","C4H7NaO2","Sodium Salt","NaB, Butanoic acid sodium salt","[Na+].CCCC([O-])=O",-0.556,0,0,2]
["S2008","Taurine","a5","L8000-21","in 10mM Water","Others","Others","Taurine is an organic acid widely distributed in animal tissues.",125.15,"107-35-7","<1","N/A",{"v":20,"d":"20.00"},159.81,"http://selleckchem.com/products/Taurine.html","C2H7NO3S","free base","N/A","NCC[S](O)(=O)=O",-1.243,0,1,2]
["S2048","Clindamycin Phosphate","b5","L8000-21","in 10mM Water","Antibiotics","Microbiology","Clindamycin Phosphate (NSC 618653) is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM.",504.96,"24729-96-2","<1","N/A",{"v":101,"d":"101.00"},200.02,"http://selleckchem.com/products/clindamycin-phosphate.html","C18H34ClN2O8PS","free base","NSC 618653","CCCC1CC(N(C)C1)C(=O)NC(C(C)Cl)C2OC(SC)C(O[P](O)(O)=O)C(O)C2O",1.205,3,3,9]
["S2076","Lisinopril dihydrate","c5","L8000-21","in 10mM Water","ACE,RAAS","Endocrinology & Hormones","Lisinopril dihydrate(MK-521 dihydrate) is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes.",441.52,"83915-83-7","<1","N/A",{"v":20,"d":"20.00"},49.32,"http://selleckchem.com/products/lisinopril-zestril.html","C21H35N3O7","free base","MK-521 dihydrate","NCCCCC(NC(CCC1=CC=CC=C1)C(O)=O)C(=O)N2CCCC2C(O)=O",-3.673,3,2,12]
["S2129","Fudosteine","d5","L8000-21","in 10mM Water","Others","Metabolism","Fudosteine is a cysteine derivative and a MUC5AC mucin hypersecretion inhibitor, used as a muco-active agent with indications for chronic respiratory diseases.",179.24,"13189-98-5","<1","N/A",{"v":36,"d":"36.00"},200.85,"http://selleckchem.com/products/Fudosteine.html","C6H13NO3S","free base","N/A","NC(CSCCCO)C(O)=O",-3.373,1,2,6]
["S2133","Gabapentin","e5","L8000-21","in 10mM Water","GABA Receptor","Neuronal Signaling","Gabapentin is a GABA analogue, used to treat seizures and neuropathic pain.",171.24,"60142-96-3","<1","N/A",{"v":34,"d":"34.00"},198.55,"http://selleckchem.com/products/Gabapentin(Neurontin).html","C9H17NO2","Free Base","N/A","NCC1(CCCCC1)CC(O)=O",-1.486,1,1,3]
["S2462","Donepezil HCl","f5","L8000-21","in 10mM Water","AChR","Neuronal Signaling","Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively.",{"v":416,"d":"416.00"},"120011-70-3","<1","N/A",{"v":5,"d":"5.00"},12.02,"http://selleckchem.com/products/Donepezil-hydrochloride(Aricept).html","C24H29NO3.HCl","Hydrochloride","N/A","Cl.COC1=C(OC)C=C2C(=O)C(CC3CCN(CC3)CC4=CC=CC=C4)CC2=C1",4.951,3,0,6]
["S2490","Neostigmine Bromide","g5","L8000-21","in 10mM Water","AChR","Neuronal Signaling","Neostigmine Bromide is a reversible acetylcholinesterase inhibitor.",{"v":303.2,"d":"303.20"},"114-80-7","<1","N/A",{"v":60,"d":"60.00"},197.89,"http://selleckchem.com/products/Neostigmine-bromide(Prostigmin).html","C12H19N2O2.Br","Bromide","N/A","[Br-].CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C",-1.907,2,0,3]
["S2507","Salbutamol Sulfate","h5","L8000-21","in 10mM Water","Adrenergic Receptor","Neuronal Signaling","Salbutamol Sulfate (Albuterol, Ventolin, Aerolin, Ventorlin, Asthalin, Asthavent) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 µM.",337.39,"51022-70-9","<1","N/A",{"v":68,"d":"68.00"},201.55,"http://selleckchem.com/products/Salbutamol-sulfate(Albuterol).html","C13H21NO3.H2SO4","Sulfate","Albuterol, Ventolin, Aerolin, Ventorlin, Asthalin, Asthavent","CC(C)(C)NCC(O)C1=CC=C(O)C(=C1)CO.O[S](O)(=O)=O",0.334,0,4,5]
["S2527","Methacycline HCl","a6","L8000-21","in 10mM Water","Antibiotics","Microbiology","Methacycline HCl (Rondomycin) is a tetracycline antibiotic, and also an inhibitor of epithelial–mesenchymal transition (EMT) with IC50 of roughly 5 μM, used to treat various infections.",478.88,"3963-95-9",{"v":3,"d":"3.00"},6.26,{"v":5,"d":"5.00"},10.44,"http://selleckchem.com/products/Methacycline-hydrochloride-Physiomycine.html","C22H22N2O8.HCl","Hydrochloride","Rondomycin","Cl.CN(C)C1C2C(O)C3C(=C)C4=CC=CC(=C4C(=O)C3=C(O)C2(O)C(=O)C(=C1O)C(N)=O)O",-0.565,3,5,2]
["S2539","Lomefloxacin HCl","b6","L8000-21","in 10mM Water","Antibiotics","Microbiology","Lomefloxacin HCl is a hydrochloride salt of lomefloxacin and is a fluoroquinolone antibiotic.",387.81,"98079-52-8",{"v":1,"d":"1.00"},2.58,{"v":6,"d":"6.00"},15.47,"http://selleckchem.com/products/Lomefloxacin-hydrochloride-Maxaquin.html","C17H19F2N3O3.HCl","Hydrochloride","N/A","Cl.CCN1C=C(C(O)=O)C(=O)C2=CC(=C(N3CCNC(C)C3)C(=C12)F)F",-0.446,2,1,3]
["S3013","Plerixafor (AMD3100) 8HCl","c6","L8000-21","in 10mM Water","CXCR,HIV","GPCR & G Protein","Plerixafor (AMD3100, JM 3100,Plerixafor Octahydrochloride,AMD3100 octahydrochloride,SID791 octahydrochloride) 8HCl is the hydrochloride of Plerixafor, a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively. Plerixafor can be used as an anti-HIV agent.",794.47,"155148-31-5","<1","N/A",{"v":100,"d":"100.00"},125.87,"http://selleckchem.com/products/plerixafor-8hcl-db06809.html","C28H54N8.8HCl","Octahydrochloride","JM 3100 8HCl,Plerixafor Octahydrochloride,AMD3100 octahydrochloride,SID791 octahydrochloride","Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl.C1CNCCNCCCN(CCNC1)CC2=CC=C(CN3CCCNCCNCCCNCC3)C=C2",2.536,0,6,4]
["S3048","Solifenacin succinate","d6","L8000-21","in 10mM Water","AChR","Neuronal Signaling","Solifenacin succinate (YM905) is a urinary antispasmodic of the antimuscarinic class.",480.55,"242478-38-2",{"v":3,"d":"3.00"},6.24,{"v":96,"d":"96.00"},199.77,"http://selleckchem.com/products/solifenacin-succinate.html","C23H26N2O.C4H6O4","Succinate","YM905","OC(=O)CCC(O)=O.O=C(OC1CN2CCC1CC2)N3CCC4=C(C=CC=C4)C3C5=CC=CC=C5",0.635,4,0,6]
["S3050","Palonosetron HCl","e6","L8000-21","in 10mM Water","5-HT Receptor","Neuronal Signaling","Palonosetron HCl (RS 25259, RS 25259 197) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.",332.87,"135729-62-3","<1","N/A",{"v":67,"d":"67.00"},201.28,"http://selleckchem.com/products/palonosetron-hcl.html","C19H24N2O.HCl","HCL","RS 25259, RS 25259 197","Cl.O=C1N(CC2CCCC3=CC=CC1=C23)C4CN5CCC4CC5",3.127,1,0,1]
["S3056","Miltefosine","f6","L8000-21","in 10mM Water","Akt","PI3K/Akt/mTOR","Miltefosine (Hexadecylphosphocholine) inhibits PI3K/Akt activity with ED50 of 17.2 μM and 8.1 μM in carcinoma cell lines A431 and HeLa, first oral drug for Visceral leishmaniasis, effective against both promastigotes and amastigotes.",407.57,"58066-85-6","<1","N/A",{"v":81,"d":"81.00"},198.74,"http://selleckchem.com/products/miltefosine-hexadecylphosphocholine.html","C21H46NO4P","free base","Hexadecylphosphocholine","CCCCCCCCCCCCCCCCO[P]([O-])(=O)OCC[N+](C)(C)C",3.722,2,0,20]
["S3058","Danofloxacin Mesylate","g6","L8000-21","in 10mM Water","Bacterial","Microbiology","Danofloxacin (CP-76136-27) is a fluoroquinolone antibacterial for veterinary use, with MIC90 of 0.28 μM.",453.48,"119478-55-6","<1","N/A",{"v":91,"d":"91.00"},200.67,"http://selleckchem.com/products/danofloxacin-mesylate.html","C19H20FN3O3.CH4O3S","Mesylate","CP-76136-27","CN1CC2CC1CN2C3=CC4=C(C=C3F)C(=O)C(=CN4C5CC5)C(O)=O.C[S](O)(=O)=O",-1.539,2,0,3]
["S3072","(R)-baclofen","h6","L8000-21","in 10mM Water","GABA Receptor","Neuronal Signaling","(R)-baclofen (STX 209) is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.",213.66,"69308-37-8","<1","N/A",{"v":8,"d":"8.00"},37.44,"http://selleckchem.com/products/r-baclofen.html","C10H12ClNO2","free base","STX 209","NCC(CC(O)=O)C1=CC=C(Cl)C=C1",{"v":-1.06,"d":"-1.060"},1,1,4]
["S3146","Tripelennamine HCl","a7","L8000-21","in 10mM Water","Histamine Receptor","Neuronal Signaling","Tripelennamine (Pyribenzamine) is a widely used H1 antagonist, inhibiting PhIP glucuronidation with IC50 of 30 μM.",291.82,"154-69-8",{"v":2,"d":"2.00"},6.85,{"v":58,"d":"58.00"},198.75,"http://selleckchem.com/products/tripelennamine-hydrochloride.html","C16H21N3.HCl","HCl","Pyribenzamine HCl","Cl.CN(C)CCN(CC1=CC=CC=C1)C2=NC=CC=C2",3.484,1,0,6]
["S3148","Ibandronate sodium monohydrate","b7","L8000-21","in 10mM Water","Others","Others","Ibandronate (BM-21.0955, BM-210955, RPR-102289A) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.",360.23,"138926-19-9","<1","N/A",{"v":72,"d":"72.00"},199.87,"http://selleckchem.com/products/ibandronate-sodium.html","C9H23NO7P2.Na.H2O","sodium monohydrate","BM-21.0955, BM-210955, RPR-102289A","O.[NaH].CCCCCN(C)CCC(O)([P](O)(O)=O)[P](O)(O)=O",0.477,0,0,9]
["S3174","L-Arginine HCl (L-Arg)","c7","L8000-21","in 10mM Water","NOS","Immunology & Inflammation","L-Arginine(L-Arg,(S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.",210.66,"1119-34-2","<1","N/A",{"v":42,"d":"42.00"},199.37,"http://selleckchem.com/products/l-Arginine-hydrochloride.html","C6H14N4O2.HCl","HCl","(S)-(+)-Arginine hydrochloride","Cl.NC(CCCNC(N)=N)C(O)=O",-3.449,1,3,6]
["S3649","Ceftazidime","d7","L8000-21","in 10mM Water","Anti-infection,Selection Antibiotics for Transfected Cell","Microbiology","Ceftazidime(GR20263) is a third-generation cephalosporin that has activity against Gram-negative bacilli, including Pseudomonas aeruginosa.",546.58,"72558-82-8",{"v":4,"d":"4.00"},7.32,{"v":100,"d":"100.00"},182.96,"http://selleckchem.com/products/ceftazidime.html","C22H22N6O7S2","inner salt","GR20263","CC(C)(O\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)C[N+]3=CC=CC=C3)C4=CSC(=N4)N)C(O)=O",-0.693,6,2,9]
["S3662","Pirenzepine dihydrochloride","e7","L8000-21","in 10mM Water","AChR","Neuronal Signaling","Pirenzepine is an antimuscarinic agent which inhibits gastric acid secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular and urinary functions.",424.32,"29868-97-1",{"v":1,"d":"1.00"},2.36,{"v":84,"d":"84.00"},197.96,"http://selleckchem.com/products/pirenzepine-dihydrochloride.html","C19H21N5O2.2HCl","dihydrochloride","N/A","Cl.Cl.CN1CCN(CC1)CC(=O)N2C3=C(C=CC=C3)C(=O)NC4=CC=CN=C24",1.803,3,1,2]
["S3667","Imipenem","f7","L8000-21","in 10mM Water","β-lactamase","Microbiology","Imipenem acts as an inhibitor of AmpC β-lactamase and is an antibiotic useful for the treatment of a number of bacterial infections.",317.36,"74431-23-5",{"v":1,"d":"1.00"},3.15,{"v":63,"d":"63.00"},198.51,"http://selleckchem.com/products/imipenem.html","C12H17N3O4S.H2O","hydrate","N/A","O.CC(O)C1C2CC(=C(N2C1=O)C(O)=O)SCCNC=N",-1.825,2,2,7]
["S3748","Acamprosate Calcium","g7","L8000-21","in 10mM Water","GABA Receptor","Transmembrane Transporters","Acamprosate (N-Acetylhomotaurine, Calcium acetylhomotaurinate,N-acetylhomotaurinate) is a synthetic compound with a chemical structure similar to the amino acid neurotransmitter gamma-aminobutyric acid (GABA) and the amino acid neuromodulator taurine.",200.24,"77337-73-6","<1","N/A",{"v":40,"d":"40.00"},199.76,"http://selleckchem.com/products/acamprosate-calcium.html","C5H11NO4S.1/2Ca","calcium salt","N-Acetylhomotaurine Calcium, calcium acetylhomotaurinate,N-acetylhomotaurinate","CC(=O)NCCC[S]([O-])(=O)=O",{"v":-2.67,"d":"-2.670"},1,1,4]
["S3752","isoleucine","h7","L8000-21","in 10mM Water","Others","Others","Isoleucine (Ile) is a non-polar, uncharged (at physiological pH), aliphatic amino acid that is used in the biosynthesis of proteins.",131.17,"73-32-5","<1","N/A",{"v":26,"d":"26.00"},198.22,"http://selleckchem.com/products/isoleucine.html","C6H13NO2","free base","Ile","CCC(C)C(N)C(O)=O",{"v":0,"d":"0.000"},0,0,0]
["S3861","Sodium Demethylcantharidate","a8","L8000-21","in 10mM Water","PP2A","PI3K/Akt/mTOR","Demethylcantharidin (norcantharidin) is a synthetic analogue of cantharidin and has potent antitumor activity.",208.14,"13114-29-9","<1","N/A",{"v":41,"d":"41.00"},196.98,"http://selleckchem.com/products/sodium-demethylcantharidate.html","C8H9O5.Na","free base","Sodium norcantharidin","OC(=O)C1C2CCC(O2)C1C(=O)O[Na]",{"v":0,"d":"0.000"},0,0,0]
["S3963","DL-Glutamine","b8","L8000-21","in 10mM Water","Others","Others","DL-Glutamine (Glutamin, 2-amino-4-carbamoylbutanoic acid) is a non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes.",146.14,"6899-04-3","<1","N/A",{"v":29,"d":"29.00"},198.44,"http://selleckchem.com/products/dl-glutamine.html","C5H10N2O3","free base","Glutamin, 2-amino-4-carbamoylbutanoic acid","NC(CCC(N)=O)C(O)=O",{"v":0,"d":"0.000"},0,0,0]
["S3973","L-SelenoMethionine","c8","L8000-21","in 10mM Water","ROS","Immunology & Inflammation","L-SelenoMethionine (SeMet), a naturally occurring amino acid, is a major food-form of selenium. It has been used as a supplement, and exhibits some important functions like cancer prevention and antioxidative defense.",196.11,"3211-76-5","<1","N/A",{"v":39,"d":"39.00"},198.87,"http://selleckchem.com/products/l-selenomethionine.html","C5H11NO2Se","free base","N/A","C[Se]CCC(N)C(O)=O",{"v":0,"d":"0.000"},0,0,0]
["S4008","Pemirolast potassium","d8","L8000-21","in 10mM Water","Histamine Receptor","Neuronal Signaling","Pemirolast potassium (BMY26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.",{"v":266.3,"d":"266.30"},"100299-08-9","<1","N/A",{"v":53,"d":"53.00"},199.02,"http://selleckchem.com/products/pemirolast-bmy-26517-potassium.html","C10H7N6O.K","Potassium","BMY26517","[K+].CC1=CC=CN2C(=O)C(=CN=C12)C3=NN=N[N-]3",-1.246,5,0,1]
["S4027","Flavoxate HCl","e8","L8000-21","in 10mM Water","AChR","Neuronal Signaling","Flavoxate (NSC-114649) is a muscarinic AChR antagonist with IC50 of 12.2 μM.",427.92,"3717-88-2",{"v":3,"d":"3.00"},7.01,{"v":10,"d":"10.00"},23.37,"http://selleckchem.com/products/flavoxate-hcl.html","C24H25NO4.HCl","hydrochloride","NSC-114649","Cl.CC1=C(OC2=C(C=CC=C2C(=O)OCCN3CCCCC3)C1=O)C4=CC=CC=C4",4.876,4,0,6]
["S4028","Dexamethasone Sodium Phosphate","f8","L8000-21","in 10mM Water","Autophagy,Complement System,COVID-19,COX,IL Receptor","Immunology & Inflammation","Dexamethasone (Dexamethasone 21-phosphate disodium salt) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator  that has anti-inflammatory and immunosuppressant effects.",{"v":516.4,"d":"516.40"},"55203-24-2","<1","N/A",{"v":103,"d":"103.00"},199.46,"http://selleckchem.com/products/dexamethasone-sodium-phosphate.html","C22H30FO8P.2Na","Disodium salt","Dexamethasone 21-phosphate disodium salt","[Na+].[Na+].CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO[P]([O-])([O-])=O",-0.541,3,1,4]
["S4030","Gentamicin Sulfate","g8","L8000-21","in 10mM Water","Antibiotics,Antibiotics for Mammalian Cell Culture,Antibiotics for Plant Cell Culture,Selection Antibiotics for Transfected Cell","Microbiology","Gentamycin Sulfate (NSC-82261, SCH9724) is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms.","N/A","1405-41-0","<1","N/A",{"v":100,"d":"100.00"},{"v":10,"d":"10.00"},"http://selleckchem.com/products/gentamicin-sulfate.html","H2SO4.xUnspecified","Sulfate","NSC-82261, SCH9724","CCN.CNC(C)C.CNC1C(O)C(OCC1(C)O)OC2C(N)CC(N)C(OC3OC(CCC3N)[R])C2O.CC(C)N.O[S](O)(=O)=O",{"v":0,"d":"0.000"},0,0,0]
["S4094","Tetramisole HCl","h8","L8000-21","in 10mM Water","Parasite","Microbiology","Tetramisole(R-829,(±)-Tetramisole hydrochloride) is a mixture of dextro- and levo isomers used as an anthelmintic.",240.75,"5086-74-8","<1","N/A",{"v":41,"d":"41.00"},{"v":170.3,"d":"170.30"},"http://selleckchem.com/products/tetramisole-hcl.html","C11H12N2S.HCl","Hydrochloride","R-829,(±)-Tetramisole hydrochloride","Cl.C1CN2CC(N=C2S1)C3=CC=CC=C3",2.672,1,0,1]
["S4108","Clodronate Disodium","a9","L8000-21","in 10mM Water","Others","Metabolism","Clodronate Disodium, a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.",288.86,"22560-50-5","<1","N/A",{"v":72,"d":"72.00"},249.26,"http://selleckchem.com/products/clodronate-disodium.html","CH4Cl2O6P0.2Na","Disodium salt","N/A","[Na+].[Na+].O[P]([O-])(=O)C(Cl)(Cl)[P](O)([O-])=O",-1.706,0,0,2]
["S4117","Histamine Phosphate","b9","L8000-21","in 10mM Water","Histamine Receptor","Neuronal Signaling","Histamine(Histamine diphosphate) acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors.",307.14,"51-74-1","<1","N/A",{"v":42,"d":"42.00"},136.75,"http://selleckchem.com/products/histamine-phosphate.html","C5H9N.2H3O4P","Phosphate","Histamine diphosphate","NCCC1=C[NH]C=N1.O[P](O)(O)=O.O[P](O)(O)=O",-1.651,1,2,2]
["S4121","Succinylcholine Chloride Dihydrate","c9","L8000-21","in 10mM Water","AChR","Neuronal Signaling","Succinylcholine Chloride Dihydrate (Suxamethonium) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.",397.34,"6101-15-1",{"v":1,"d":"1.00"},2.52,{"v":79,"d":"79.00"},198.82,"http://selleckchem.com/products/succinylcholine-suxamethonium-chloride-dihydrate.html","C14H30N2O4.2Cl.2H2O","Chloride","Suxamethonium Chloride Dihydrate","O.O.[Cl-].[Cl-].C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C",-8.102,4,0,11]
["S4127","Terbutaline Sulfate","d9","L8000-21","in 10mM Water","Adrenergic Receptor","GPCR & G Protein","Terbutaline Sulfate(Terbutaline hemisulfate) is a selective β2-adrenergic receptor agonist with IC50 of 53 nM.",548.65,"23031-32-5","<1","N/A",{"v":100,"d":"100.00"},182.27,"http://selleckchem.com/products/terbutaline-sulfate.html","C24H38N2O6.H2SO4","Sulfate","Terbutaline hemisulfate","CC(C)(C)NCC(O)C1=CC(=CC(=C1)O)O.CC(C)(C)NCC(O)C2=CC(=CC(=C2)O)O.O[S](O)(=O)=O",2.001,0,8,8]
["S4144","Amprolium HCl","e9","L8000-21","in 10mM Water","Vitamin","Metabolism","Amprolium chloride is a thiamin antagonist, which prevents carbohydrate synthesis by blocking thiamine uptake.",315.24,"137-88-2",{"v":2,"d":"2.00"},6.34,{"v":63,"d":"63.00"},199.85,"http://selleckchem.com/products/amprolium-hcl.html","C14H19N4.HCl.Cl","Hydrochloride","N/A","Cl.[Cl-].CCCC1=NC=C(C[N+]2=C(C)C=CC=C2)C(=N1)N",-0.036,2,1,4]
["S4157","Chloroquine diphosphate","f9","L8000-21","in 10mM Water","Anti-infection,ATM/ATR,Autophagy,COVID-19,TLR","PI3K/Akt/mTOR","Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. Chloroquine is also an inhibitor of toll-like receptors (TLRs).",515.86,"50-63-5","<1","N/A",{"v":100,"d":"100.00"},193.85,"http://selleckchem.com/products/chloroquine-phosphate.html","C18H26ClN3.2H3O4P","diphosphate","N/A","CCN(CC)CCCC(C)NC1=CC=NC2=C1C=CC(=C2)Cl.O[P](O)(O)=O.O[P](O)(O)=O",3.408,1,1,8]
["S4158","Ceftriaxone disodium salt hemi (heptahydrate)","g9","L8000-21","in 10mM Water","Antibiotics","Microbiology","Ceftriaxone disodium salt hemi (heptahydrate) is a third-generation cephalosporin antibiotic.",{"v":661.6,"d":"661.60"},"104376-79-6",{"v":1,"d":"1.00"},1.51,{"v":100,"d":"100.00"},151.15,"http://selleckchem.com/products/ceftriaxone-sodium-trihydrate.html","C18H16N8O7S3.7/2H2O.2Na","disodium salt hemi","N/A","O.[Na;v0].CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)CSC3=NC(=O)C(=O)NN3C)C4=CSC(=N4)N",-1.716,8,2,8]
["S4183","Paromomycin Sulfate","h9","L8000-21","in 10mM Water","Antibiotics,Antibiotics for Mammalian Cell Culture,Antibiotics for Plant Cell Culture,Selection Antibiotics for Transfected Cell","Microbiology","Paromomycin Sulfate(Aminosidine sulfate) is an aminoglycoside antibiotics inhibiting protein synthesis in non-resistant cells by binding to 16S ribosomal RNA.",713.71,"1263-89-4","<1","N/A",{"v":100,"d":"100.00"},140.11,"http://selleckchem.com/products/paromomycin-sulfate.html","C23H45N5O14.xH2SO4","Sulfate","Aminosidine sulfate","NCC1OC(OC2C(O)C(OC2CO)OC3C(O)C(N)CC(N)C3OC4OC(CO)C(O)C(O)C4N)C(N)C(O)C1O.O[S](O)(=O)=O",-9.277,6,13,9]
["S4236","Proflavine Hemisulfate","a10","L8000-21","in 10mM Water","Anti-infection,DNA/RNA Synthesis","Microbiology","Proflavine Hemisulfate is a topical antiseptic by interchelating DNA, thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands.",258.25,"1811-28-5","<1","N/A",{"v":22,"d":"22.00"},85.19,"http://selleckchem.com/products/proflavine-hemisulfate.html","C13H11N3.1/2H2SO4","Sulfate","N/A","NC1=CC=C2C=C3C=CC(=CC3=NC2=C1)N.NC4=CC=C5C=C6C=CC(=CC6=NC5=C4)N.O[S](O)(=O)=O",3.113,2,4,0]
["S4245","Sodium ascorbate","b10","L8000-21","in 10mM Water","Vitamin","Metabolism","Sodium Ascorbate (Sodium Vitamin C) is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.",198.11,"134-03-2",{"v":2,"d":"2.00"},9.94,{"v":40,"d":"40.00"},198.88,"http://selleckchem.com/products/sodium-ascorbate.html","C6H7NaO6","Sodium Salt","Sodium Vitamin C","[NaH].OCC(O)C1OC(=O)C(O)C1O",-2.229,2,4,2]
["S4254","Apramycin Sulfate","c10","L8000-21","in 10mM Water","Antibiotics","Microbiology","Apramycin Sulfate (Ai3-29795) is an aminoglycoside antibiotic, which binds to the deep groove of the RNA.",637.66,"65710-07-8","<1","N/A",{"v":100,"d":"100.00"},156.82,"http://selleckchem.com/products/apramycin-sulfate.html","C21H41N5O11.xH2SO4","Sulfate","Ai3-29795","CNC1C(O)C2OC(OC3C(N)CC(N)C(O)C3O)C(N)CC2OC1OC4OC(CO)C(N)C(O)C4O.O[S](O)(=O)=O",{"v":-7.63,"d":"-7.630"},5,11,6]
["S4298","Amifostine trihydrate","d10","L8000-21","in 10mM Water","Others","Others","Amifostine trihydrate(WR2721 trihydrate) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.",268.27,"112901-68-5","<1","N/A",{"v":42,"d":"42.00"},156.56,"http://selleckchem.com/products/amifostine.html","C5H15N2O3PS.3H2O","trihydrate","WR2721 trihydrate","O.O.O.NCCCNCCS[P](O)(O)=O",-1.471,0,2,7]
["S4360","Tolmetin Sodium","e10","L8000-21","in 10mM Water","COX","Immunology & Inflammation","Tolmetin(MCN2559) is a non-steroidal anti-inflammatory drug of the arylalkanoic acids. Tolmetin sodium dihydrate is a non-steroidal antiinflammatory agent, and acts as a non-selective COX inhibitor.",{"v":315.3,"d":"315.30"},"64490-92-2","<1",{"v":0,"d":"0.00"},{"v":63,"d":"63.00"},199.81,"http://www.selleckchem.com/products/tolmetin-sodium.html","C15H14NO3.Na.2H2O","sodium","MCN2559","O.O.C[N]1C(=CC=C1C(=O)C2=CC=C(C)C=C2)CC(=O)O[Na]",2.943,3,0,5]
["S4430","Hydroxychloroquine Sulfate (NSC 4375)","f10","L8000-21","in 10mM Water","Anti-infection,Autophagy,COVID-19,TLR","Autophagy","Hydroxychloroquine Sulfate (NSC 4375, HCQ) is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.",433.95,"747-36-4","<1","N/A",{"v":67,"d":"67.00"},{"v":154.4,"d":"154.40"},"http://selleckchem.com/products/hydroxychloroquine-sulfate.html","C18H28ClN3O5S","Sulfate","HCQ","CCN(CCO)CCCC(C)NC1=CC=NC2=CC(=CC=C12)Cl.O[S](O)(=O)=O",{"v":2.85,"d":"2.850"},1,2,9]
["S4575","Pralidoxime chloride","g10","L8000-21","in 10mM Water","AChR","Neuronal Signaling","Pralidoxime chloride (2-PAM) is an antidote to organophosphate pesticides and chemicals; An acetylcholinesterase (AChE) reactivator.",172.61,"51-15-0","<1","N/A",{"v":34,"d":"34.00"},196.98,"http://selleckchem.com/products/pralidoxime-chloride.html","C7H9N2O.Cl","chloride","2-PAM (chloride)","[Cl-].C[N+]1=C(C=CC=C1)\\C=N\\O",-1.122,1,0,1]
["S4582","Eflornithine (MDL-71782) hydrochloride hydrate","h10","L8000-21","in 10mM Water","Decarboxylase","Metabolism","Eflornithine (Difluoromethylornithine, DFMO, MDL-71782, RMI-71782, α-difluoromethylornithine) hydrochloride hydrate inhibits polyamine biosynthesis by the selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis. Its biological half-life is 8 hours.",236.64,"96020-91-6","<1","N/A",{"v":47,"d":"47.00"},198.61,"http://selleckchem.com/products/eflornithine-hydrochloride-hydrate.html","C6H12F2N2O2.HCl.H2O","hydrochloride hydrate","Difluoromethylornithine hydrochloride hydrate, DFMO hydrochloride hydrate, RMI-71782 hydrochloride hydrate, α-difluoromethylornithine hydrochloride hydrate","O.Cl.NCCCC(N)(C(F)F)C(O)=O",-3.046,1,2,5]
["S4606","Glutathione","a11","L8000-21","in 10mM Water","Glutathione","Metabolism","Glutathione (Isethion, Tathion, L-Glutathione reduced, GSH; γ-L-Glutamyl-L-cysteinyl-glycine) acts as an antioxidant, a free radical scavenger and a detoxifying agent. It is a tripeptide comprised of three amino acids (cysteine, glutamic acid, and glycine) present in most mammalian tissue.",307.32,"70-18-8","<1","N/A",{"v":61,"d":"61.00"},198.49,"http://selleckchem.com/products/glutathione.html","C10H17N3O6S","free base","Isethion, Glutathion, Tathion, L-Glutathione reduced, GSH; γ-L-Glutamyl-L-cysteinyl-glycine","NC(CCC(=O)NC(CS)C(=O)NCC(O)=O)C(O)=O",-4.772,4,3,9]
["S4653","L-Ornithine hydrochloride","b11","L8000-21","in 10mM Water","Others","Others","L-ornithine hydrochloride ((S)-2,5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle.",168.62,"3184-13-2","<1","N/A",{"v":26,"d":"26.00"},196.73,"https://www.selleckchem.com/products/l-ornithine-hydrochloride.html","C5H13ClN2O2","free base","(S)-2,5-Diaminopentanoic acid","Cl.NCCCC(N)C(O)=O",-3.697,1,2,4]
["S4671","Cefradine","c11","L8000-21","in 10mM Water","Antibiotics","Microbiology","Cefradine (Cephradine, Sefril, Anspor, Velosef) is a semi-synthetic cephalosporin antibiotic.",{"v":349.4,"d":"349.40"},"38821-53-3","<1","N/A",{"v":10,"d":"10.00"},28.62,"http://selleckchem.com/products/cefradine.html","C16H19N3O4S","free base","Cephradine, Sefril, Anspor, Cephradin, Velosef","CC1=C(N2C(SC1)C(NC(=O)C(N)C3=CCC=CC3)C2=O)C(O)=O",-2.277,3,2,4]
["S4700","4-Aminobutyric acid (GABA)","e11","L8000-21","in 10mM Water","GABA Receptor","Neuronal Signaling","4-Aminobutyric acid (4-Aminobutanoic acid, GABA, Gamma-aminobutyric acid, Piperidic acid) is a naturally occurring neurotransmitter with central nervous system (CNS) inhibitory activity.",103.12,"56-12-2","<1","N/A",{"v":20,"d":"20.00"},193.95,"http://selleckchem.com/products/4-aminobutyric-acid.html","C4H9NO2","free base","4-Aminobutanoic acid, GABA, Gamma-aminobutyric acid, Piperidic acid","NCCCC(O)=O",-3.076,1,1,3]
["S4740","Sodium ferulate","f11","L8000-21","in 10mM Water","5-HT Receptor","Neuronal Signaling","Sodium ferulate (SF, Ferulic acid sodium salt), the sodium salt of ferulic acid, is a drug used in traditional Chinese medicine for treatment of cardiovascular and cerebrovascular diseases and to prevent thrombosis.",216.17,"24276-84-4",{"v":2,"d":"2.00"},9.25,{"v":43,"d":"43.00"},198.92,"http://selleckchem.com/products/ferulic-acid-sodium.html","C10H9O4.Na","Sodium salt","Ferulic acid sodium salt","[Na+].COC1=CC(=CC=C1O)\\C=C\\C([O-])=O",0.195,1,1,3]
["S4741","Danshensu","g11","L8000-21","in 10mM Water","P450 (e.g. CYP17)","Metabolism","Danshensu (Salvianic acid A), a herbal preparation used in traditional Chinese medicine, possesses potential antitumor and anti‑angiogenesis effects. Danshensu inhibits CYP2E1 and CYP2C9 with IC50 of 36.63 and 75.76 μm, respectively.",198.17,"76822-21-4","<1","N/A",{"v":23,"d":"23.00"},116.06,"http://selleckchem.com/products/danshensu.html","C9H10O5","free base","Salvianic acid A","OC(CC1=CC=C(O)C(=C1)O)C(O)=O",0.679,1,3,3]
["S4993","Timonacic","h11","L8000-21","in 10mM Water","Others","Others","Timonacic (Thiazolidine-4-carboxylic acid, Detoxepa, Hepalidine, 1,3-Thiazolidine-4-carboxylic acid) is a cyclic sulfur amino acid derivative with potential antineoplastic and antioxidant activities.",133.17,"444-27-9",{"v":1,"d":"1.00"},7.51,{"v":27,"d":"27.00"},202.75,"http://www.selleckchem.com/products/timonacic.html","C4H7NO2S","Free Base","Thiazolidine-4-carboxylic acid, Detoxepa, Hepalidine, 1,3-Thiazolidine-4-carboxylic acid","OC(=O)C1CSCN1",-2.889,1,1,1]
["S5097","Methotrexate disodium","a2","L8000-22","in 10mM Water","Dehydrogenase,DHFR","Metabolism","Methotrexate sodium, an inhibitor of tetrahydrofolate dehydrogenase, is an antineoplastic antimetabolite with immunosuppressant properties.",{"v":498.4,"d":"498.40"},"7413-34-5","<1","N/A",{"v":99,"d":"99.00"},198.64,"http://selleckchem.com/products/methotrexate-disodium.html","C20H20N8O5.2Na","disodium salt","N/A","[Na+].[Na+].CN(CC1=NC2=C(N)N=C(N)N=C2N=C1)C3=CC=C(C=C3)C(=O)NC(CCC([O-])=O)C([O-])=O",-2.834,5,3,9]
["S5131","Homotaurine","b2","L8000-22","in 10mM Water","GABA Receptor","Neuronal Signaling","Homotaurine (Tramiprosate, Alzhemed, 3-Amino-1-propanesulfonic acid) is a synthetic organic compound that has GABAergic activity by mimicking GABA. It is a GABAA partial agonist as well as a GABAB receptor partial agonist with low efficacy.",139.17,"3687-18-1","N/A","N/A",{"v":27,"d":"27.00"},194.01,"http://selleckchem.com/products/homotaurine.html","C3H9NO3S","free base","Tramiprosate, Alzhemed, 3-Amino-1-propanesulfonic acid","NCCC[S](O)(=O)=O",{"v":0,"d":"0.000"},0,0,0]
["S5136","Calcium folinate","c2","L8000-22","in 10mM Water","DHFR","Metabolism","Calcium folinate (Leucovorin calcium, Folinic acid calcium salt, Wellcovorin) is a metabolically active, reduced form of folic acid that is rapidly absorbed and extensively metabolized in the liver to other folic acid derivatives.",{"v":511.5,"d":"511.50"},"1492-18-8","<1","N/A",{"v":100,"d":"100.00"},{"v":195.5,"d":"195.50"},"http://selleckchem.com/products/calcium-folinate.html","C20H21N7O7.Ca","calcium salt","Leucovorin calcium, Folinic acid calcium salt, Wellcovorin","[Ca++].NC1=NC(=C2N(C=O)C(CNC3=CC=C(C=C3)C(=O)NC(CCC([O-])=O)C([O-])=O)CNC2=N1)O",{"v":0,"d":"0.000"},0,0,0]
["S5267","Nylidrin Hydrochloride","d2","L8000-22","in 10mM Water","Adrenergic Receptor","Neuronal Signaling","Nylidrin Hydrochloride (Buphenine), a β-adrenergic agonist, is used therapeutically for its vasodilating effect on the peripheral circulation and possibly on the cerebral circulation as well.",335.87,"849-55-8","N/A",{"v":0,"d":"0.00"},{"v":67,"d":"67.00"},199.48,"https://www.selleckchem.com/products/nylidrin-hydrochloride.html","C19H25NO2.HCl","hydrochloride","Buphenine HCl","Cl.CC(CCC1=CC=CC=C1)NC(C)C(O)C2=CC=C(O)C=C2",4.112,0,3,7]
["S5384","UTP Trisodium Salt","e2","L8000-22","in 10mM Water","DNA/RNA Synthesis","DNA Damage/DNA Repair","Uridine-5'-triphosphate (UTP) is a pyrimidine nucleoside triphosphate and a substrate for the synthesis of RNA during transcription.",550.09,"19817-92-6","<1","N/A",{"v":100,"d":"100.00"},181.79,"http://selleckchem.com/products/utp-trisodium-salt.html","C9H15N2O15P3.3Na","Trisodium salt","N/A","[Na+].[Na+].[Na+].OC1C(O)C(OC1CO[P]([O-])(=O)O[P]([O-])(=O)O[P](O)([O-])=O)N2C=CC(=O)NC2=O",-7.518,6,3,8]
["S5524","Spermine Tetrahydrochloride","f2","L8000-22","in 10mM Water","Others","Others","Spermine (Gerontine, Neuridine, Musculamine) is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is a major natural intracellular compound capable of protecting DNA from free radical attack.",348.18,"306-67-2","<1","N/A",{"v":69,"d":"69.00"},198.17,"http://selleckchem.com/products/spermine-tetrahydrochloride.html","C10H26N4.4HCl","tetrahydrochloride","Gerontine tetrahydrochloride, Neuridine tetrahydrochloride, Musculamine tetrahydrochloride","Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN",0.024,0,4,11]
["S5526","β-Alanine","g2","L8000-22","in 10mM Water","Others","Others","β-Alanine (beta-Alanine, 3-Aminopropanoic acid) is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotransmitter by activating glycine and GABA receptors.",89.09,"107-95-9","<1","N/A",{"v":17,"d":"17.00"},190.82,"http://www.selleckchem.com/products/beta-alanine.html","C3H7NO2","Free Base","beta-Alanine, 3-Aminopropanoic acid","NCCC(O)=O",-3.397,1,1,2]
["S5533","Tobramycin sulfate","h2","L8000-22","in 10mM Water","Antibiotics,Bacterial","Microbiology","Tobramycin sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity.",1425.42,"49842-07-1","<1","N/A",{"v":100,"d":"100.00"},70.15,"https://www.selleckchem.com/products/tobramycin-sulfate.html","C36H84N10O38S5","free base","N/A","NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)CC1O.NCC4OC(OC5C(N)CC(N)C(OC6OC(CO)C(O)C(N)C6O)C5O)C(N)CC4O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O",-16.755,8,20,12]
["S5545","DL-Serine","a3","L8000-22","in 10mM Water","PKM","Metabolism","Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2.",105.09,"302-84-1","<1","N/A",{"v":8,"d":"8.00"},76.13,"http://selleckchem.com/products/dl-serine.html","C3H7NO3","salt","N/A","NC(CO)C(O)=O",-4.049,1,2,2]
["S5660","Clodronate disodium tetrahydrate","b3","L8000-22","in 10mM Water","Others","Others","Clodronate disodium tetrahydrate (clodronic acid) is a diphosphonate which affects calcium metabolism. It inhibits bone resorption and soft tissue calcification.",360.92,"88416-50-6","<1","N/A",{"v":72,"d":"72.00"},199.49,"https://www.selleckchem.com/products/clodronate-disodium-tetrahydrate.html","CH10Cl2Na2O10P2","free base","clodronic acid disodium tetrahydrate","O.O.O.O.[Na+].[Na+].O[P]([O-])(=O)C(Cl)(Cl)[P](O)([O-])=O",-2.534,0,0,2]
["S5706","Edetate Trisodium","c3","L8000-22","in 10mM Water","Others","Others","Edetate Trisodium (EDTA trisodium salt, ethylenediaminetetraacetic acid) is the organic sodium salt of ethylenediaminetetraacetic acid (EDTA). EDTA is a chelating agent capable of removing a heavy metal, such as lead or mercury, from the blood.",358.19,"150-38-9","<1","N/A",{"v":36,"d":"36.00"},100.51,"https://www.selleckchem.com/products/edetate-trisodium.html","C10H13N2Na3O8","free base","EDTA Trisodium, ethylenediaminetetraacetic acid Trisodium","[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O",-9.072,1,0,11]
["S6023","Creatine monohydrate","d3","L8000-22","in 10mM Water","Others","Others","Creatine (Methylguanidoacetic acid) is a key player in the phosphagen energy system, the primary source of ATP during short-term, high intensity activities.",149.15,"6020-87-7","N/A","N/A",5.96,39.94,"http://www.selleck.cn/products/creatine-monohydrate.html","C4H11N3O3","monohydrate","Methylguanidoacetic acid monohydrate","O.CN(CC(O)=O)C(N)=N",-1.302,1,1,3]
["S6445","Chlorophyllin (sodium copper salt)","e3","L8000-22","in 10mM Water","Others","Others","Chlorophyllin, the sodium and copper salt of chlorophyll, is an antioxidant and antimutagenic agent.",724.15,"11006-34-1","<1","N/A",{"v":13,"d":"13.00"},17.95,"http://www.selleck.cn/products/chlorophyllin.html","C34H31CuN4Na3O6","sodium copper salt","N/A","[Na+].[Na+].[Na+].[Cu++]|1|2|3|[N-]4C5=C(C)C(=C4C=C6N|1=C(C=C7[N-]|2C(=C(CC([O-])=O)C8=N|3C(=C5)C(C)C8CCC([O-])=O)C(=C7C)C([O-])=O)C(=C6C)CC)C=C",-1.452,0,0,8]
["S6488","Gadoxetate sodium","f3","L8000-22","in 10mM Water","Others","Others","Gadoxetate is a paramagnetic gadolinium-containing contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection.",725.71,"135326-22-6","N/A","N/A",{"v":100,"d":"100.00"},{"v":137.8,"d":"137.80"},"http://www.selleck.cn/products/gadoxetate-sodium.html","C23H28GdN3Na2O11","sodium","N/A","[Na+].[Na+].[Gd+3]|1|2|3|4|5|6|7|[O-]C(=O)CN|1(CCN|2(CC([O-]|3)=O)CC([O-]|4)=O)CC(CC8=CC=C(OCC)C=C8)N|5(CC([O-]|6)=O)CC([O-]|7)=O",{"v":-3.48,"d":"-3.480"},1,0,4]
["S7785","Pemetrexed Disodium Hydrate","h3","L8000-22","in 10mM Water","Apoptosis related,Autophagy,DHFR","Metabolism","Pemetrexed Disodium Hydrate (LY-231514) is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively. Pemetrexed Disodium Hydrate stimulates autophagy and apoptosis.",516.42,"357166-30-4","<1","N/A",{"v":100,"d":"100.00"},193.64,"http://selleckchem.com/products/pemetrexed-disodium-hydrate.html","C20H21N5O6.5/2H2O.2Na","Disodium Hydrate","LY-231514 Disodium Hydrate","NC1=NC(=O)C2=C([NH]C=C2CCC3=CC=C(C=C3)C(=O)NC(CCC(=O)O[Na])C(=O)O[Na])N1",{"v":2.06,"d":"2.060"},7,4,11]
["S9353","L-serine","a4","L8000-22","in 10mM Water","Others","Others","L-serine, one of the so-called non-essential amino acids, plays a central role in cellular proliferation.",105.09,"56-45-1","N/A",{"v":0,"d":"0.00"},{"v":21,"d":"21.00"},199.82,"https://www.selleckchem.com/products/l-serine.html","C3H7NO3","free base","N/A","NC(CO)C(O)=O",-4.049,1,2,2]
["P1011","Eptifibatide Acetate","b4","L8000-22","in 10mM Water","5-alpha Reductase","Angiogenesis","Eptifibatide Acetate is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue. A disulfide bridge forms between mercaptopropionyl and cysteine. Eptifibatide prevents platelet aggregation. One study shows the inhibition of platelet glycoprotein IIb/IIIa in acute coronary syndromes.",{"v":832.4,"d":"832.40"},"148031-34-9","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://selleckchem.com/products/eptifibatide-acetate.html","C35H49N11O9S2","Acetate","Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2","NC(=N)NCCCCC1NC(=O)CCSSCC(NC(=O)C2CCCN2C(=O)C(CC3=C[NH]C4=C3C=CC=C4)NC(=O)C(CC(O)=O)NC(=O)CNC1=O)C(N)=O",{"v":0,"d":"0.000"},0,0,0]
["P1017","Octreotide (SMS 201-995) acetate","d4","L8000-22","in 10mM Water","N/A","Neuronal Signaling","Octreotide (SMS 201-995) acetate is the acetate salt of a cyclic octapeptide. It is a long-acting octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin.","1019.28 (free base)","79517-01-4","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://selleckchem.com/products/octreotide-acetate.html","C49H66N10O10S2.xC2H4O2","Acetate","D-Phe-c[Cys-Phe-D-Trp-Lys-Thr-Cys]-Thr-ol","CC(O)C(CO)NC(=O)C1CSSCC(NC(=O)C(N)CC2=CC=CC=C2)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=C[NH]C5=C4C=CC=C5)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)N1",{"v":0,"d":"0.000"},0,0,0]
["P1025","Atosiban Acetate","e4","L8000-22","in 10mM Water","N/A","Angiogenesis","Atosiban Acetate is a competitive oxytocin and vasopressin antagonist by exhibiting high affinity for both receptors. It is used to treat preterm labors.",{"v":994.2,"d":"994.20"},"90779-69-4","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://www.selleckchem.com/peptide/atosiban-acetate.html","C43H67N11O12S2","Acetate","c[Mpr-D-Tyr(OEt)-Ile-Thr-Asn-Cys]-Pro-Orn-Gly-NH2","CCOC1=CC=C(CC2NC(=O)CCSSCC(NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(NC2=O)C(C)CC)C(C)O)C(=O)N3CCCC3C(=O)NC(CCCN)C(=O)NCC(N)=O)C=C1",{"v":0,"d":"0.000"},0,0,0]
["P1030","Salmon Calcitonin Acetate","f4","L8000-22","in 10mM Water","N/A","N/A","Salmon Calcitonin Acetate, which is more potent and longer lasting than human CT, has been used widely for the treatment of osteoporosis, paget's disease, hypercalcemic shock and chronic pain in terminal cancer patients.",3431.85,"47931-85-1","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://www.selleckchem.com/peptide/salmon-calcitonin-acetate.html","C145H240N44O48S2","Acetate","N/A","CC(C)CC(NNC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)C(=O)C(CC1=CC=C(O)C=C1)NN2CCCC2C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)O)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CO)C(=O)NCC(=O)NC(C(C)O)C(=O)N3CCCC3C(N)=O)C(=O)C(=O)C(CCCCN)NC(=O)C(CC4=CN=C[NH]4)NC(=O)C(CC(C)C)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(N)=O)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(NC(=O)C5CSSCC(N)C(=O)NC(CO)C(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)N5)C(C)C",{"v":0,"d":"0.000"},0,0,0]
["P1039","Somatostatin Acetate","g4","L8000-22","in 10mM Water","5-alpha Reductase","Neuronal Signaling","Somatostatin Acetate is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones.",1637.88,"38916-34-6",{"v":-1,"d":"-1.00"},"N/A",{"v":100,"d":"100.00"},61.05,"http://www.selleck.cn/products/somatostatin-acetate.html","C76H104N18O19S2","Free Base","Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH(Cys3-Cys14)","CC(N)C(=O)NCC(=O)NC1CSSCC(NC(=O)C(CO)NC(=O)C(NC(=O)C(CC2=CC=CC=C2)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(CC3=C[NH]C4=CC=CC=C34)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(CC6=CC=CC=C6)NC(=O)C(CC(N)=O)NC(=O)C(CCCCN)NC1=O)C(C)O)C(C)O)C(O)=O.CC(O)=O",-8.729,16,21,26]
["P1084","Desmopressin Acetate","a5","L8000-22","in 10mM Water","Vasopressin Receptor","GPCR & G Protein","Desmopressin is a synthetic octapeptide, and an analogue of human hormone arginine vasopressin with antidiuretic and coagulant activities. It is a selective agonist for the vasopressin V2 receptor (V2R).",1129.27,"62288-83-9","N/A","N/A","N/A",{"v":10,"d":"10.00"},"https://www.selleckchem.com/products/desmopressin-acetate-.html","C46H64N14O12S2.C2H4O2","Acetate","N/A","CC(O)=O.NC(=N)NCCCC(NC(=O)C1CCCN1C(=O)C2CSSCCC(=O)NC(CC3=CC=C(O)C=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)N2)C(=O)NCC(N)=O",{"v":0,"d":"0.000"},0,0,0]
["P1085","Angiotensin II human Acetate","b5","L8000-22","in 10mM Water","Angiotensin Receptor","GPCR & G Protein","Angiotensin II (angII) is an octapeptide hormone which affects the activities of heart, kidney, vasculature and brain. It works via binding to specific receptors present on cell membranes.",1106.23,"68521-88-0","N/A","N/A","N/A",{"v":10,"d":"10.00"},"https://www.selleckchem.com/products/angiotensin-ii-human-acetate.html","C52H75N13O14","Acetate","N/A","CCC(C)C(NC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C(NC(=O)C(CCCNC(N)=N)NC(=O)C(N)CC(O)=O)C(C)C)C(=O)NC(CC2=C[NH]C=N2)C(=O)N3CCCC3C(=O)NC(CC4=CC=CC=C4)C(O)=O.CC(O)=O",{"v":0,"d":"0.000"},0,0,0]
["S1671","(6-)ε-​Aminocaproic acid","d5","L8000-22","in 10mM Water","Others","Others","(6-)ε-​Aminocaproic acid is a derivative and analogue of the amino acid lysine.",131.17,"60-32-2","N/A","N/A",{"v":26,"d":"26.00"},198.22,"http://selleckchem.com/products/Aminocaproic-acid(Amicar).html","C6H13NO2","free base","N/A","NCCCCCC(O)=O",-2.164,1,1,5]
["S3076","Foscarnet Sodium","e5","L8000-22","in 10mM Water","Reverse Transcriptase","Microbiology","Foscarnet Sodium (Phosphonoformate) inhibits viral RNA polymerases, reverse transcriptase, and DNA polymerases through noncompetitive inhibition with dNTPs.",191.95,"63585-09-1","N/A","N/A",{"v":3,"d":"3.00"},15.63,"http://selleckchem.com/products/foscarnet-sodium.html","CNa3O5P","Sodium","Phosphonoformate","[Na+].[Na+].[Na+].[O-]C(=O)[P]([O-])([O-])=O",-4.033,0,0,1]
["S4519","Citric acid trilithium salt tetrahydrate","f5","L8000-22","in 10mM Water","Others","Others","Citric acid trilithium salt tetrahydrate (Trilithium citrate tetrahydrate, Lithium citrate tribasic tetrahydrate) is a pharmaceutical and construction material. It is commonly used in HPLC gradient elution for quantification of amino acids.",281.98,"6080-58-6","N/A","N/A",{"v":56,"d":"56.00"},{"v":198.6,"d":"198.60"},"http://selleckchem.com/products/citric-acid-trilithium-salt-tetrahydrate.html","C6H5Li3O7&bull;4H2O","free base","Trilithium citrate tetrahydrate, Lithium citrate tribasic tetrahydrate","O.O.O.O.[Li]OC(=O)CC(O)(CC(=O)O[Li])C(=O)O[Li]",-1.875,6,0,8]
["S2441","Estramustine phosphate sodium","g5","L8000-22","in 10mM Water","Microtubule Associated","Cytoskeletal Signaling","Estramustine phosphate sodium (EMP, Emcyt, Estracyt) is an antitumour drug with a unique dual mode of action. Estrone and estradiol, products of the metabolism of estramustine phosphate sodium, have shown antigonadotrophic activity resulting in reduced testosterone levels. Estramustine(the cytotoxic metabolite produced by dephosphorylation of estramustine phosphate sodium) is an antiprostatic tumor drug with antimicrotubule effects.",564.35,"52205-73-9","<1","N/A",{"v":100,"d":"100.00"},{"v":177.2,"d":"177.20"},"http://www.selleck.cn/products/estramustine-phosphate-sodium.html","C23H30Cl2NNa2O6P","phosphate sodium","EMP, Emcyt, Estracyt","[Na+].[Na+].CC12CCC3C(CCC4=C3C=CC(=C4)OC(=O)N(CCCl)CCCl)C1CCC2O[P]([O-])([O-])=O",3.131,3,0,8]
["P1088","Lanreotide acetate","h5","L8000-22","in 10mM Water","GHSR","Endocrinology & Hormones","Lanreotide (Laromustine, Angiopeptin, BIM 23014, Dermopeptin, Ipstyl, ITM-014, Somatulina, Somatuline, Lanreotidum) acetate, an analog of the native somatostatin peptide, is a physiological inhibitor of growth hormone (GH). Lanreotide also has antitumoral effects.",1156.38,"2378114-72-6",{"v":-1,"d":"-1.00"},"N/A",{"v":23,"d":"23.00"},19.89,"https://www.selleckchem.com/products/lanreotide-acetate.html","C56H73N11O12S2","Acetate","Laromustine, Angiopeptin, BIM 23014, BIM 23014C, BM 23014, Dermopeptin, Ipstyl, ITM-014, ITM-014T, Somatulina, Somatuline, Lanreotidum","CC(C)C1NC(=O)C(CCCCN)NC(=O)C(CC2=C[NH]C3=C2C=CC=C3)NC(=O)C(CC4=CC=C(O)C=C4)NC(=O)C(CSSCC(NC1=O)C(=O)NC(C(C)O)C(N)=O)NC(=O)C(N)CC5=CC6=CC=CC=C6C=C5.CC(O)=O",-0.979,9,13,17]
["S3096","L-Histidine monohydrochloride monohydrate","b6","L8000-22","in 10mM Water","Others","Metabolism","L-Histidine monohydrochloride monohydrate (L-Histidine hydrochloride hydrate, H-His-OH.HCl.H2O), a structural analogue of the essential amino acid L-histidine, is a reversible inhibitor of protein biosynthesis which evokes disparate responses from non-tumorigenic and tumorigenic cells in culture.",209.63,"5934-29-2","<1","N/A",{"v":42,"d":"42.00"},200.35,"https://www.selleckchem.com/products/l-histidine-monohydrochloride-monohydrate.html","C6H12ClN3O3","Monohydrate","L-Histidine hydrochloride hydrate, H-His-OH.HCl.H2O","O.Cl.NC(CC1=CN=C[NH]1)C(O)=O",-3.538,2,2,3]
["S1314","Zoledronic acid (ZOL 446)","c6","L8000-22","in 10mM Water","Apoptosis related,Autophagy,Ras,Rho","Cell Cycle","Zoledronic acid (ZA, Zoledronate, CGP-4244, GP42446A, ZOL 446, Zometa, Zomera, Aclasta, Reclast), a potent osteoclast inhibitor, induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho. Zoledronic acid (ZA) also induces autophagy.",272.09,"118072-93-8","<1","N/A",{"v":4,"d":"4.00"},{"v":14.7,"d":"14.70"},"http://www.selleckchem.com/products/Zoledronic-Acid.html","C5H10N2O7P2","Free Base","ZA, Zoledronate, CGP-4244, GP42446A, ZOL 446, Zometa, Zomera, Aclasta, Reclast","OC(C[N]1C=CN=C1)([P](O)(O)=O)[P](O)(O)=O",-1.209,1,0,4]
["S6289","Gentamicin","d6","L8000-22","in 10mM Water","Antiviral","Microbiology","Gentamicin, an aminoglycoside class of bactericidal antibiotic, is effective against gram-negative bacterial infections.",1390.71,"1403-66-3","<1","N/A",{"v":100,"d":"100.00"},71.91,"http://www.selleckchem.com/products/gentamicin.html","C60H123N15O21","free base","N/A","CNC(C)C1CCC(N)C(O1)OC2C(N)CC(N)C(OC3OCC(C)(O)C(NC)C3O)C2O.CNC4C(O)C(OCC4(C)O)OC5C(N)CC(N)C(OC6OC(CN)CCC6N)C5O.CNC7C(O)C(OCC7(C)O)OC8C(N)CC(N)C(OC9OC(CCC9N)C(C)N)C8O",-12.679,12,21,19]
["S6872","Merbromin","e6","L8000-22","in 10mM Water","3C-Like Protease,Bacterial","Proteases","Merbromin (Mercurochrome), a xanthene dye and an antibacterial agent, is the first of a series of antiseptics that contained mercury, also is a mixed-type inhibitor of 3CLpro due to its ability of increasing the KM and decreasing the Kcat of 3CLpro.",752.68,"129-16-8","<1","N/A",{"v":100,"d":"100.00"},132.86,"http://www.selleckchem.com/products/merbromin.html","C20H10Br2HgO6.2Na","free base","Mercurochrome, Merbromine, Mercurocol, Sodium mercurescein, Asceptichrome, Supercrome, Brocasept, Cinfacromin","[NaH].[NaH].O[Hg]C1=C(O)C(=CC2=C1OC3=CC(=C(Br)C=C3C24OC(=O)C5=C4C=CC=C5)O)Br",4.622,3,2,1]
["E0532","Menotropin","f6","L8000-22","in 10mM Water","Estrogen/progestogen Receptor","Endocrinology & Hormones","Menotropin (Human Menopausal Gonadotrophin) is a hormonally active medication for the treatment of fertility disturbances, which are extracted from the urine of postmenopausal women.",142.24,"61489-71-2","<1","N/A",{"v":28,"d":"28.00"},196.85,"http://www.selleckchem.com/products/menotropin.html","C9H18O","free base","Human Menopausal Gonadotrophin","CC(C)(C)CCCCC=O",2.767,1,0,5]
["E2638","Tricine","g6","L8000-22","in 10mM Water","Others","Others","Tricine (N-[Tris(hydroxymethyl)methyl]glycine) is a buffer component for separation of low molecular weight peptides.",179.17,"5704-04-1","<1","N/A",{"v":36,"d":"36.00"},200.93,"http://www.selleckchem.com/products/tricine.html","C6H13NO5","free base","N-[Tris(hydroxymethyl)methyl]glycine","OCC(CO)(CO)NCC(O)=O",-5.173,1,4,6]
["S2542","Phenformin (NSC-756501) HCl","a7","L8000-22","in 10mM Water","AMPK","PI3K/Akt/mTOR","Phenformin HCl (NSC-756501, Phenethylbiguanide) is a hydrochloride salt of phenformin that is an anti-diabetic drug from the biguanide class. It activates AMPK, increasing activity and phosphorylation.",241.72,"834-28-6","N/A","N/A","N/A",">10","http://selleckchem.com/products/Phenformin-hydrochloride.html","C10H15N5.HCl","Hydrochloride","Phenethylbiguanide HCl","Cl.NC(=N)NC(=N)NCCC1=CC=CC=C1",1.339,0,3,6]
["S1023","Erlotinib (OSI-774) HCl","a2","L8000-23","in 2mM DMSO","Autophagy,EGFR","Protein Tyrosine Kinase","Erlotinib (OSI-774, CP358774, NSC 718781) HCl is an EGFR inhibitor with IC50 of 2 nM in cell-free assays, >1000-fold more sensitive for EGFR than human c-Src or v-Abl.",{"v":429.9,"d":"429.90"},"183319-69-9",{"v":4,"d":"4.00"},{"v":9.3,"d":"9.30"},"<1","N/A","http://selleckchem.com/products/Erlotinib-Hydrochloride.html","C22H23N3O4.HCl","Hydrochloride","CP358774, NSC 718781,OSI-774 HCl","Cl.COCCOC1=C(OCCOC)C=C2C(=NC=NC2=C1)NC3=CC=CC(=C3)C#C",4.691,6,1,10]
["S1046","Vandetanib (ZD6474)","b2","L8000-23","in 2mM DMSO","Apoptosis related,Autophagy,EGFR,ROS,VEGFR","Protein Tyrosine Kinase","Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 with IC50 of 40 nM in a cell-free assay. It also inhibits VEGFR3 and EGFR with IC50 of 110 nM and 500 nM, respectively. Not sensitive to PDGFRβ, Flt1, Tie-2 and FGFR1 with IC50 of 1.1-3.6 μM. No activity against MEK, CDK2, c-Kit, erbB2, FAK, PDK1, Akt and IGF-1R with IC50 above 10 μM. Vandetanib (ZD6474) increases apoptosis and induces autophagy by increasing the level of reactive oxygen species (ROS).",475.35,"443913-73-3",{"v":4,"d":"4.00"},8.41,"<1","N/A","http://selleckchem.com/products/Vandetanib.html","C22H24BrFN4O2","free base","ZD6474","COC1=CC2=C(C=C1OCC3CCN(C)CC3)N=CN=C2NC4=C(F)C=C(Br)C=C4",5.087,4,1,6]
["S1211","Imiquimod (R-837)","c2","L8000-23","in 2mM DMSO","Immunology & Inflammation related","Immunology & Inflammation","Imiquimod (Aldara,R-837,S-26308) is a novel synthetic agent with immune response modifying activity.",{"v":240.3,"d":"240.30"},"99011-02-6",{"v":1,"d":"1.00"},4.16,"<1","N/A","http://selleckchem.com/products/Imiquimod.html","C14H16N4","free base","Aldara,R-837, S-26308","CC(C)C[N]1C=NC2=C(N)N=C3C=CC=CC3=C12",2.722,2,1,2]
["S1288","Camptothecin (NSC-100880)","d2","L8000-23","in 2mM DMSO","ADC Cytotoxin,Apoptosis related,MicroRNA,Topoisomerase","DNA Damage/DNA Repair","Camptothecin (NSC-100880, CPT, Campathecin, (S)-(+)-Camptothecin) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM in a cell-free assay. Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2.",348.35,"7689-03-4",{"v":3,"d":"3.00"},8.61,"<1","N/A","http://selleckchem.com/products/Camptothecine.html","C20H16N2O4","Free Base","CPT, Campathecin, (S)-(+)-Camptothecin","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC=CC5=C4)C2=O",1.746,4,0,1]
["S1353","Ketoconazole (R 41400)","e2","L8000-23","in 2mM DMSO","Androgen Receptor,Fungal,P450 (e.g. CYP17)","Metabolism","Ketoconazole (R 41400) inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively. Ketoconazole is an androgen biosynthesis inhibitor.",531.43,"65277-42-1",{"v":5,"d":"5.00"},9.41,"<1","N/A","http://selleckchem.com/products/Ketoconazole.html","C26H28Cl2N4O4","free base","R 41400","CC(=O)N1CCN(CC1)C2=CC=C(OCC3COC(C[N]4C=CN=C4)(O3)C5=CC=C(Cl)C=C5Cl)C=C2",{"v":3.61,"d":"3.610"},5,0,7]
["S1424","Prazosin HCl","f2","L8000-23","in 2mM DMSO","Adrenergic Receptor","GPCR & G Protein","Prazosin HCl (cp-12299-1) is a competitive alpha-1 adrenoceptor antagonist, used to treat high blood pressure or benign prostatic hyperplasia.",419.86,"19237-84-4",{"v":4,"d":"4.00"},9.53,"<1","N/A","http://selleckchem.com/products/Prazosin-hydrochloride.html","C19H21N5O4.HCl","Hydrochloride","cp-12299-1","Cl.COC1=CC2=C(C=C1OC)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N",2.489,6,1,4]
["S1463","Ofloxacin","g2","L8000-23","in 2mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Ofloxacin (DL8280) is a synthetic broad-spectrum antimicrobial agent.",361.37,"82419-36-1",{"v":1,"d":"1.00"},2.77,"<1","N/A","http://www.selleck.cn/products/Ofloxacin(Floxin).html","C18H20FN3O4","Free Base","DL8280","CC1COC2=C(N3CCN(C)CC3)C(=CC4=C2N1C=C(C(O)=O)C4=O)F",-1.374,3,0,2]
["S1464","Marbofloxacin","h2","L8000-23","in 2mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Marbofloxacin is a potent antibiotic inhibiting bacterial DNA replication.",362.36,"115550-35-1",{"v":3,"d":"3.00"},8.28,"<1","N/A","http://selleckchem.com/products/Marbofloxacin.html","C17H19FN4O4","free base","N/A","CN1CCN(CC1)C2=C(F)C=C3C(=O)C(=CN4N(C)COC2=C34)C(O)=O",-2.038,3,0,2]
["S1507","Irbesartan","a3","L8000-23","in 2mM DMSO","Angiotensin Receptor","GPCR & G Protein","Irbesartan (BMS-186295, SR-47436,APROVEL) is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM.",428.53,"138402-11-6",{"v":4,"d":"4.00"},9.33,"<1","N/A","http://selleckchem.com/products/Irbesartan(Avapro).html","C25H28N6O","free base","BMS-186295, SR-47436,APROVEL","CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=N[NH]N=N5",{"v":0,"d":"0.000"},0,0,0]
["S1509","Norfloxacin","b3","L8000-23","in 2mM DMSO","Topoisomerase","DNA Damage/DNA Repair","Norfloxacin (MK-0366) is a broad-spectrum antibiotic. Norfloxacin (MK-0366) targets bacterial gyrase and topoisomerase IV enzymes.",319.33,"70458-96-7",{"v":3,"d":"3.00"},9.39,"<1","N/A","http://selleckchem.com/products/Norfloxacin(Norxacin).html","C16H18FN3O3","free base","MK-0366","CCN1C=C(C(O)=O)C(=O)C2=CC(=C(C=C12)N3CCNCC3)F",{"v":0,"d":"0.000"},0,0,0]
["S1615","Risperidone","c3","L8000-23","in 2mM DMSO","5-HT Receptor","Neuronal Signaling","Risperidone (R-64766) is a mutil-targeted antagonist for dopamine, serotonin, adrenergic and histamine receptors, used to treat schizophrenia and bipolar disorder.",410.48,"106266-06-2",{"v":4,"d":"4.00"},9.74,"<1","N/A","http://selleckchem.com/products/Risperidone(Risperdal).html","C23H27FN4O2","free base","R-64766","CC1=C(CCN2CCC(CC2)C3=NOC4=C3C=CC(=C4)F)C(=O)N5CCCCC5=N1",3.317,4,0,4]
["S1617","Sulfapyridine","d3","L8000-23","in 2mM DMSO","Bacterial","Microbiology","Sulfapyridine  is a sulfonamide antibacterial.",249.29,"144-83-2",{"v":2,"d":"2.00"},8.02,"<1","N/A","http://selleckchem.com/products/Sulfapyridine(Dagenan).html","C11H11N3O2S","free base","N/A","NC1=CC=C(C=C1)[S](=O)(=O)NC2=NC=CC=C2",0.959,3,2,3]
["S1642","Methyldopa","e3","L8000-23","in 2mM DMSO","5-HT Receptor,Adrenergic Receptor,Decarboxylase,Dopamine Receptor","Metabolism","Methyldopa (Aldomet) is a DOPA decarboxylase competitive inhibitor with an ED50 of 21.8 mg/kg.",211.21,"555-30-6",{"v":2,"d":"2.00"},9.47,"<1","N/A","http://selleckchem.com/products/Methyldopa(Aldomet).html","C10H13NO4","free base","N/A","CC(N)(CC1=CC(=C(O)C=C1)O)C(O)=O",{"v":0,"d":"0.000"},0,0,0]
["S1698","Torsemide","f3","L8000-23","in 2mM DMSO","Chloride Channel","Transmembrane Transporters","Torsemide (AC-4464, JDL-464) is a pyridyl sulfonylurea with a chemical structure between that of traditional loop diuretics and Cl- channel blockers, used to treat hypertension.",348.42,"56211-40-6",{"v":3,"d":"3.00"},8.61,"<1","N/A","http://selleckchem.com/products/Torsemide(Demadex).html","C16H20N4O3S","free base","AC-4464, JDL-464","CC(C)NC(=O)N[S](=O)(=O)C1=C(NC2=CC(=CC=C2)C)C=CN=C1",{"v":0,"d":"0.000"},0,0,0]
["S1707","Eplerenone (CGP 30083)","g3","L8000-23","in 2mM DMSO","Mineralocorticoid Receptor","Endocrinology & Hormones","Eplerenone (CGP 30083, SC-66110) is a mineralocorticoid receptor antagonist, and blocks the action of aldosterone, used to control high blood pressure.",414.49,"107724-20-9",{"v":4,"d":"4.00"},9.65,"<1","N/A","http://selleckchem.com/products/Eplerenone(Inspra).html","C24H30O6","free base","CGP 30083, SC-66110","COC(=O)C1CC2=CC(=O)CCC2(C)C34OC3CC5(C)C(CCC56CCC(=O)O6)C14",{"v":0,"d":"0.000"},0,0,0]
["S1724","Paliperidone","h3","L8000-23","in 2mM DMSO","Dopamine Receptor","Neuronal Signaling","Paliperidone, the main active metabolite of Risperidone, is a potent serotonin-2A and dopamine-2 receptor antagonist, used in the treatment of schizophrenia.",426.48,"144598-75-4",{"v":4,"d":"4.00"},9.38,"<1","N/A","http://selleckchem.com/products/Paliperidone(Invega).html","C23H27FN4O3","free base","N/A","CC1=C(CCN2CCC(CC2)C3=NOC4=C3C=CC(=C4)F)C(=O)N5CCCC(O)C5=N1",{"v":0,"d":"0.000"},0,0,0]
["S1837","Flubendazole","a4","L8000-23","in 2mM DMSO","Autophagy,Parasite","Autophagy","Flubendazole (Flumoxanal, NSC 313680) is an autophagy inducer by targeting Atg4B, used to treat internal parasite and worm infection.",313.28,"31430-15-6",{"v":3,"d":"3.00"},9.58,"<1","N/A","http://selleckchem.com/products/flubendazole-flutelmium.html","C16H12FN3O3","free base","Flumoxanal, NSC 313680","COC(=O)NC1=NC2=C([NH]1)C=C(C=C2)C(=O)C3=CC=C(F)C=C3",{"v":3.26,"d":"3.260"},4,2,4]
["S1851","Oxibendazole","b4","L8000-23","in 2mM DMSO","Parasite","Microbiology","Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets.",249.27,"20559-55-1",{"v":1,"d":"1.00"},4.01,"<1","N/A","http://selleckchem.com/products/oxibendazole.html","C12H15N3O3","Free Base","N/A","CCCOC1=CC=C2N=C(NC(=O)OC)[NH]C2=C1",2.506,4,2,5]
["S1977","Sarafloxacin HCl","c4","L8000-23","in 2mM DMSO","Antibiotics","Microbiology","Sarafloxacin HCl (A-56620) is a hydrochloride salt form of sarafloxacin which is a quinolone antibiotic drug with IC50 of 0.96 μg/L.",421.83,"91296-87-6",{"v":4,"d":"4.00"},9.48,"<1","N/A","http://selleckchem.com/products/sarafloxacin-hydrochloride.html","C20H17F2N3O3.HCl","Hydrochloride","A-56620 HCl","Cl.OC(=O)C1=CN(C2=CC=C(F)C=C2)C3=C(C=C(F)C(=C3)N4CCNCC4)C1=O",{"v":0,"d":"0.000"},0,0,0]
["S1986","Meclizine 2HCl","d4","L8000-23","in 2mM DMSO","CAR,Histamine Receptor","Neuronal Signaling","Meclizine (NSC 28728,Meclozine dihydrochloride) is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation properties, also an agonist ligand for mCAR (constitutive androstane receptor) and an inverse agonist for hCAR.",463.87,"1104-22-9",{"v":4,"d":"4.00"},8.62,"<1","N/A","http://selleckchem.com/products/meclizine-dihydrochloride.html","C25H27Cl2N2.2HCl","Dihydrochloride","NSC 28728,Meclozine dihydrochloride","Cl.Cl.CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(Cl)C=C4",{"v":0,"d":"0.000"},0,0,0]
["S2035","Epalrestat (ONO-2235)","e4","L8000-23","in 2mM DMSO","Aldose Reductase,Carbohydrate Metabolism","Metabolism","Epalrestat (ONO-2235) is an aldose reductase inhibitor with IC50 of 72 nM.",{"v":319.4,"d":"319.40"},"82159-09-9",{"v":3,"d":"3.00"},9.39,"<1","N/A","http://selleckchem.com/products/epalrestat.html","C15H13NO3S2","free base","ONO-2235","CC(=C/C1=CC=CC=C1)\\C=C2/SC(=S)N(CC(O)=O)C2=O",3.442,2,0,4]
["S2047","Lornoxicam","f4","L8000-23","in 2mM DMSO","COX","Neuronal Signaling","Lornoxicam (Chlortenoxicam) is a non-steroidal COX-1/COX-2 inhibitor, used as an anti-inflammatory drug to treat pain, osteoarthritis, and rheumatoid arthritis.",371.82,"70374-39-9",{"v":3,"d":"3.00"},8.07,"<1","N/A","http://selleckchem.com/products/lornoxicam-xefo.html","C13H10ClN3O4S2","free base","Chlortenoxicam","CN1C(=C(O)C2=C(C=C(Cl)S2)[S]1(=O)=O)C(=O)NC3=NC=CC=C3",0.913,4,2,2]
["S2110","Vinpocetine","g4","L8000-23","in 2mM DMSO","Sodium Channel","Transmembrane Transporters","Vinpocetine (RGH-4405,Ethyl apovincaminate,AY 27255) is a selective inhibitor of voltage-sensitive sodium channel for the treatment of stroke, vascular dementia  and Alzheimer's disease.",350.45,"42971-09-5",{"v":3,"d":"3.00"},8.56,"<1","N/A","http://selleckchem.com/products/vinpocetine-cavinton.html","C22H26N2O2","free base","RGH-4405,Ethyl apovincaminate,AY 27255","CCOC(=O)C1=CC2(CC)CCCN3CCC4=C(C23)[N]1C5=CC=CC=C45",{"v":0,"d":"0.000"},0,0,0]
["S2150","Neratinib (HKI-272)","h4","L8000-23","in 2mM DMSO","EGFR,HER2","Protein Tyrosine Kinase","Neratinib (HKI-272) is a highly selective HER2 and EGFR inhibitor with IC50 of 59 nM and 92 nM in cell-free assays; weakly inhibits KDR and Src, no significant inhibition to Akt, CDK1/2/4, IKK-2, MK-2, PDK1, c-Raf and c-Met. Phase 3.",557.04,"698387-09-6",{"v":5,"d":"5.00"},8.98,"<1","N/A","http://selleckchem.com/products/Neratinib(HKI-272).html","C30H29ClN6O3","free base","N/A","CCOC1=C(NC(=O)\\C=C\\CN(C)C)C=C2C(=C1)N=CC(=C2NC3=CC=C(OCC4=NC=CC=C4)C(=C3)Cl)C#N",4.881,5,2,11]
["S2206","Fostamatinib (R788) disodium","a5","L8000-23","in 2mM DMSO","Syk","Angiogenesis","Fostamatinib disodium  (R788, Tamatinib Fosdium), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.",624.42,"1025687-58-4",{"v":6,"d":"6.00"},9.61,"<1","N/A","http://selleckchem.com/products/R788(Fostamatinib-disodium).html","C23H24FN6O9P.2Na","Sodium Salt","Tamatinib Fosdium","[Na+].[Na+].COC1=C(OC)C(=CC(=C1)NC2=NC=C(F)C(=N2)NC3=CC=C4OC(C)(C)C(=O)N(CO[P]([O-])([O-])=O)C4=N3)OC",{"v":0,"d":"0.000"},0,0,0]
["S2251","(-)-Huperzine A (HupA)","b5","L8000-23","in 2mM DMSO","AChR,GluR","Neuronal Signaling","(-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4.",242.32,"102518-79-6",0.66,2.72,"<1","N/A","http://selleckchem.com/products/(-)-Huperzine-A.html","C15H18N2O","Free Base","N/A","C\\C=C/1C2CC3=C(C=CC(=O)N3)C1(N)CC(=C2)C",1.056,1,2,0]
["S2292","Diosmin","c5","L8000-23","in 2mM DMSO","AhR","Metabolism","Diosmin is an agonist of the aryl hydrocarbon receptor (AhR). Diosmin is a semisynthetic phlebotropic agent and a flavonoid found in a variety of citrus fruits.",608.55,"520-27-4",{"v":6,"d":"6.00"},9.86,"<1","N/A","http://selleckchem.com/products/Diosmin.html","C28H32O15","Free Base","N/A","COC1=C(O)C=C(C=C1)C2=CC(=O)C3=C(O2)C=C(OC4OC(COC5OC(C)C(O)C(O)C5O)C(O)C(O)C4O)C=C3O",-0.395,7,8,7]
["S2476","Itraconazole (R 51211)","d5","L8000-23","in 2mM DMSO","Autophagy,Fungal,Hedgehog/Smoothened,P450 (e.g. CYP17)","Stem Cells & Wnt","Itraconazole (R 51211) is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy.",705.65,"84625-61-6",{"v":7,"d":"7.00"},9.92,"<1","N/A","http://selleckchem.com/products/Itraconazole(Sporanox).html","C35H38Cl2N8O4","free base","R 51211","CCC(C)N1N=CN(C1=O)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(OCC5COC(C[N]6C=NC=N6)(O5)C7=CC=C(Cl)C=C7Cl)C=C4",6.434,7,0,11]
["S2530","7-Aminocephalosporanic acid","e5","L8000-23","in 2mM DMSO","Antibiotics","Microbiology","7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates.",272.28,"957-68-6",{"v":1,"d":"1.00"},3.67,"<1","N/A","http://selleckchem.com/products/7-Aminocephalosporanic-acid.html","C10H12N2O5S","Free Base","N/A","CC(=O)OCC1=C(N2C(SC1)C(N)C2=O)C(O)=O",-3.745,4,1,4]
["S2582","Trazodone HCl","f5","L8000-23","in 2mM DMSO","5-HT Receptor","Neuronal Signaling","Trazodone HCl (AF-1161, KB-831) is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.",408.32,"25332-39-2",{"v":4,"d":"4.00"},{"v":9.8,"d":"9.80"},"<1","N/A","http://selleckchem.com/products/trazodone-hydrochloride-desyrel.html","C19H22ClN5O.HCl","Hydrochloride","AF-1161, KB-831","Cl.ClC1=CC(=CC=C1)N2CCN(CCCN3N=C4C=CC=CN4C3=O)CC2",{"v":0,"d":"0.000"},0,0,0]
["S2597","Oseltamivir Phosphate","g5","L8000-23","in 2mM DMSO","Influenza Virus,Neuraminidase","Microbiology","Oseltamivir Phosphate(Tamiflu) is a potent and selective inhibitor of the neuraminidase that is essential for replication of influenza A and B viruses, used to prevent influenza.",{"v":410.4,"d":"410.40"},"204255-11-8",{"v":4,"d":"4.00"},9.75,"<1","N/A","http://selleckchem.com/products/oseltamivir-phosphate-Tamiflu.html","C16H28N2O4.H3PO4","Phosphate salt","Tamiflu","CCOC(=O)C1=CC(OC(CC)CC)C(NC(C)=O)C(N)C1.O[P](O)(O)=O",0.577,4,2,8]
["S2788","Capmatinib (INCB28060)","h5","L8000-23","in 2mM DMSO","Apoptosis related,c-Met,Wnt/beta-catenin","Protein Tyrosine Kinase","Capmatinib (INCB28060, INC280, NVP-INC280) is a novel, ATP-competitive inhibitor of c-MET with IC50 of 0.13 nM in a cell-free assay, inactive against RONβ, as well as EGFR and HER-3. Capmatinib (INCB28060) inhibits Wnt/β-catenin and EMT signaling pathways and induces apoptosis in diffuse gastric cancer positive for c-MET amplification. Phase 1.",412.42,"1029712-80-8",{"v":2,"d":"2.00"},4.85,"<1","N/A","http://selleckchem.com/products/incb28060.html","C23H17FN6O","Free Base","INC280, NVP-INC280","CNC(=O)C1=CC=C(C=C1F)C2=N[N]3C(=CN=C3N=C2)CC4=CC=C5N=CC=CC5=C4",3.246,5,1,4]
["S2920","Mozavaptan","a6","L8000-23","in 2mM DMSO","Vasopressin Receptor","GPCR & G Protein","Mozavaptan (OPC-31260) is a novel competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM, respectively.",427.54,"137975-06-5",{"v":1,"d":"1.00"},2.34,"<1","N/A","http://selleckchem.com/products/mozavaptan.html","C27H29N3O2","Free Base","OPC-31260","CN(C)C1CCCN(C(=O)C2=CC=C(NC(=O)C3=C(C)C=CC=C3)C=C2)C4=C1C=CC=C4",4.654,2,1,4]
["S3059","Enrofloxacin","b6","L8000-23","in 2mM DMSO","Antibiotics","Microbiology","Enrofloxacin (BAY-Vp2674, PD160788) is a fluoroquinolone antibiotic.",359.39,"93106-60-6",{"v":3,"d":"3.00"},8.35,"<1","N/A","http://selleckchem.com/products/enrofloxacin.html","C19H22FN3O3","free base","BAY-Vp2674, PD160788","CCN1CCN(CC1)C2=CC3=C(C=C2F)C(=O)C(=CN3C4CC4)C(O)=O",{"v":0,"d":"0.000"},0,0,0]
["S3770","Sodium Aescinate","c6","L8000-23","in 2mM DMSO","NF-κB","NF-κB","Sodium Aescinate (SA, Escin Sodium Salt) is a widely-applied triterpene saponin product derived from horse chestnut seeds, possessing vasoactive and organ-protective activities with oral or injection administration in the clinic.  Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway.",1123.21,"20977-05-3",{"v":10,"d":"10.00"},{"v":8.9,"d":"8.90"},"N/A","N/A","http://selleckchem.com/products/sodium-aescinate.html","C54H83NaO23","sodium salt","Escin sodium salt","CC(OC(C)=O)C(C)C(=O)OCC12C(O)C3OC1CC4(C)C(=CCC5C6(C)CCC(OC7OC(C(OC8OC(CO)C(O)C(O)C8O)C(O)C7OC9OCC(O)C(O)C9O)C(=O)O[Na])C(C)(CO)C6CCC45C)C2CC3(C)C",-0.485,13,10,17]
["S3801","Sodium Houttuyfonate","d6","L8000-23","in 2mM DMSO","Anti-infection","Microbiology","Sodium Houttuyfonate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.",330.42,"1847-58-1",{"v":2,"d":"2.00"},6.05,"<1","N/A","http://selleckchem.com/products/sodium-houttuyfonate.html","C14H27O5S.Na","sodium salt","N/A","[Na+].CCCCCCCCCCCCOC(=O)C[S]([O-])(=O)=O",2.026,2,0,14]
["S3821","Nuciferine","e6","L8000-23","in 2mM DMSO","5-HT Receptor,5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Nuciferine (Sanjoinine E, (-)-Nuciferine, VLT 049) is a major active aporphine alkaloid from the leaves of N. nucifera Gaertn and possesses anti-hyperlipidemia, anti-hypotensive, anti-arrhythmic, and insulin secretagogue activities. Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 μM) and 5-HT6 (EC50=700 nM), an agonist at 5-HT1A (EC50=3.2 μM) and D4 (EC50=2 μM) receptor.",295.38,"475-83-2",{"v":2,"d":"2.00"},6.77,"<1","N/A","http://selleckchem.com/products/nuciferine.html","C19H21NO2","free base","Sanjoinine E, (-)-Nuciferine, VLT 049","COC1=C(OC)C2=C3C(CC4=C2C=CC=C4)N(C)CCC3=C1",3.567,2,0,2]
["S3891","Vincamine","f6","L8000-23","in 2mM DMSO","Others","Others","Vincamine (Angiopac, Devincan, Equipur, Minorin, Novicet, Oxybral, Perval, Sostenil, Tripervan), an indole alkaloid found in the leaves of V. minor and C. roseus, is a peripheral vasodilator that increases blood flow to the brain.",354.44,"1617-90-9",{"v":3,"d":"3.00"},8.46,"N/A","N/A","http://selleckchem.com/products/vincamine.html","C21H26N2O3","free base","Angiopac, Devincan, Equipur, Minorin, Novicet, Oxybral, Perval, Sostenil, Tripervan","CCC12CCCN3CCC4=C(C13)[N](C5=CC=CC=C45)C(O)(C2)C(=O)OC",3.546,2,0,3]
["S4033","Sennoside A","g6","L8000-23","in 2mM DMSO","MAO","Metabolism","Sennoside A (NSC 112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.",862.74,"81-27-6","N/A",{"v":2,"d":"2.00"},"<1","N/A","http://selleckchem.com/products/sennoside-a.html","C42H38O20","Free Base","NSC 112929","OCC1OC(OC2=CC=CC3=C2C(=O)C4=C(O)C=C(C=C4C3C5C6=C(C(=O)C7=C(O)C=C(C=C57)C(O)=O)C(=CC=C6)OC8OC(CO)C(O)C(O)C8O)C(O)=O)C(O)C(O)C1O",0.409,8,10,9]
["S4126","Retinyl (Vitamin A) Palmitate","h6","L8000-23","in 2mM DMSO","Vitamin","Metabolism","Retinyl (Vitamin A) Palmitate is a more stable, synthetic version of the essential nutrient vitamin A joined to palmitic acid.",524.86,"79-81-2",{"v":3,"d":"3.00"},5.72,"<1","N/A","http://selleckchem.com/products/vitamin-a-palmitate.html","C36H60O2","Free Base","Vitamin A palmitate","CCCCCCCCCCCCCCCC(=O)OC/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C",12.293,2,0,21]
["S4262","Ebastine","a7","L8000-23","in 2mM DMSO","Histamine Receptor","Neuronal Signaling","Ebastine(LAS-W 090,RP64305) is a potent H1-histamine receptor antagonist, used for allergic disorders.",469.66,"90729-43-4",{"v":4,"d":"4.00"},8.52,"<1","N/A","http://selleckchem.com/products/ebastine.html","C32H39NO2","free base","LAS-W 090,RP64305","CC(C)(C)C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)OC(C3=CC=CC=C3)C4=CC=CC=C4",6.582,2,0,10]
["S4605","Folic acid","b7","L8000-23","in 2mM DMSO","Vitamin","Metabolism","Folic acid (Folacin, Vitamin B9, Vitamin M, Pteroylglutamic acid, Folate), a B vitamin, plays an important role in cell division and in the synthesis of amino acids and nucleic acids like DNA.",{"v":441.4,"d":"441.40"},"59-30-3",{"v":2,"d":"2.00"},4.53,"<1","N/A","http://selleckchem.com/products/folic-acid.html","C19H19N7O6","free base","Folacin, Vitamin B9, Vitamin M, Pteroylglutamic acid, Folate","NC1=NC(=O)C2=C(N1)N=CC(=N2)CNC3=CC=C(C=C3)C(=O)NC(CCC(O)=O)C(O)=O",-0.232,7,4,9]
["S4642","Dolutegravir Sodium","c7","L8000-23","in 2mM DMSO","Integrase","Microbiology","Dolutegravir Sodium (GSK-1349572A) is a HIV integrase inhibitor with IC50 of 2.7 nM.",441.36,"1051375-19-9",{"v":2,"d":"2.00"},4.53,"<1","N/A","http://www.selleck.cn/products/dolutegravir-sodium.html","C20H19F2N3O5.Na","Sodium","GSK-1349572A","CC1CCOC2CN3C=C(C(=O)NCC4=C(F)C=C(F)C=C4)C(=O)C(=C3C(=O)N12)O[Na]",0.391,5,1,4]
["S5018","Mebhydrolin napadisylate","d7","L8000-23","in 2mM DMSO","ADC Cytotoxin,Histamine Receptor","Neuronal Signaling","Mebhydrolin Napadisylate (Diazoline, Diazolin, Incidal, Omeril) is classified as an antihistamine drug classes used to treat allergies.",841.05,"6153-33-9",{"v":8,"d":"8.00"},9.51,"N/A","N/A","http://selleckchem.com/products/mebhydrolin-napadisylate.html","C48H48N4O6S2","salt","Diazoline, Diazolin, Incidal, Omeril","CN1CCC2=C(C1)C3=C(C=CC=C3)[N]2CC4=CC=CC=C4.CN5CCC6=C(C5)C7=C(C=CC=C7)[N]6CC8=CC=CC=C8.O[S](=O)(=O)C9=C%10C=CC=C(C%10=CC=C9)[S](O)(=O)=O",9.536,0,0,6]
["S5232","Alectinib (CH5424802) hydrochloride","e7","L8000-23","in 2mM DMSO","ALK","Protein Tyrosine Kinase","Alectinib (AF802, CH5424802, RO5424802, RG-7853) is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase.",519.08,"1256589-74-8",{"v":2,"d":"2.00"},3.85,"<1","N/A","http://selleckchem.com/products/alectinib-hydrochloride.html","C30H34N4O2.HCl","hydrochloride","AF802, RO5424802, RG-7853","Cl.CCC1=C(C=C2C(=C1)C(=O)C3=C([NH]C4=C3C=CC(=C4)C#N)C2(C)C)N5CCC(CC5)N6CCOCC6",5.585,2,1,3]
["S5677","Xanthopterin Hydrate","f7","L8000-23","in 2mM DMSO","Others","Others","Xanthopterin, isolated from butterfly wings and found in many other sources, replace folic acid in the nutrition of many animal species.",197.15,"5979-01-1",{"v":1,"d":"1.00"},5.07,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/xanthopterin-hydrate.html","C6H7N5O3","Hydrate","N/A","O.NC1=NC(=C2N=C(O)C=NC2=N1)O",-0.128,4,3,0]
["S7128","Tazemetostat (EPZ-6438)","g7","L8000-23","in 2mM DMSO","EZH1/2,Histone Methyltransferase","Epigenetics","Tazemetostat (EPZ-6438, E7438) is a potent, and selective EZH2 inhibitor with Ki and IC50 of 2.5 nM and 11 nM in cell-free assays, exhibiting a 35-fold selectivity versus EZH1 and >4,500-fold selectivity relative to 14 other HMTs.",572.74,"1403254-99-8",{"v":5,"d":"5.00"},8.73,"<1","N/A","http://selleckchem.com/products/epz-6438.html","C34H44N4O4","free base","E7438","CCN(C1CCOCC1)C2=C(C)C(=CC(=C2)C3=CC=C(CN4CCOCC4)C=C3)C(=O)NCC5=C(C)C=C(C)NC5=O",3.506,4,2,9]
["S7756","Indoximod (NLG-8189）","h7","L8000-23","in 2mM DMSO","IDO/TDO","Metabolism","Indoximod (NLG-8189, 1-Methyl-D-tryptophan, 1-MT), a methylated tryptophan, acts as an IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor, and reverses IDO-mediated immune suppression. Phase 2.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!",218.25,"110117-83-4",{"v":1,"d":"1.00"},4.58,"<1","N/A","http://selleckchem.com/products/indoximod-nlg-8189.html","C12H14N2O2","Free Base","1-Methyl-D-tryptophan, 1-MT","C[N]1C=C(CC(N)C(O)=O)C2=CC=CC=C12",-1.106,1,1,3]
["S8229","Brigatinib (AP26113)","a8","L8000-23","in 2mM DMSO","ALK,EGFR,FLT3,IGF-1R,ROS1","Angiogenesis","Brigatinib (AP26113) is a potent and selective ALK (IC50, 0.6 nM) and ROS1 (IC50, 0.9 nM) inhibitor. It also inhibits IGF-1R, FLT3, and mutant variants of FLT3 (D835Y) and EGFR with lower potentcy.",584.09,"1197953-54-0",{"v":3,"d":"3.00"},5.14,"<1","N/A","http://www.selleck.cn/products/brigatinib-ap26113.html","C29H39ClN7O2P","Free Base","N/A","COC1=C(NC2=NC(=C(Cl)C=N2)NC3=CC=CC=C3[P](C)(C)=O)C=CC(=C1)N4CCC(CC4)N5CCN(C)CC5",5.084,6,2,8]
["S5098","Gefitinib hydrochloride","b8","L8000-23","in 2mM DMSO","EGFR","Protein Tyrosine Kinase","Gefitinib (ZD1839) is an EGFR inhibitor with IC50s of 15.5 nM and 823.3 nM for WT EGFR and EGFR (858R/T790M), respectively.",483.36,"184475-55-6","N/A",{"v":2,"d":"2.00"},{"v":1,"d":"1.00"},2.07,"http://selleckchem.com/products/gefitinib-hydrochloride.html","C22H24ClFN4O3.HCl","hydrochloride","ZD1839 hydrochloride","Cl.COC1=CC2=C(C=C1OCCCN3CCOCC3)C(=NC=N2)NC4=CC(=C(F)C=C4)Cl",4.585,5,1,8]
["S1502","Cephalexin","c8","L8000-23","in 2mM DMSO","Antibiotics,Bacterial","Microbiology","Cephalexin (Cefalexin) is an antibiotic that can treat a number of bacterial infections.",347.39,"15686-71-2","N/A",{"v":2,"d":"2.00"},"N/A","N/A","http://selleckchem.com/products/Cephalexin-(Cefalexin).html","C16H17N3O4S","free base","Cefalexin","CC1=C(N2C(SC1)C(NC(=O)C(N)C3=CC=CC=C3)C2=O)C(O)=O",-2.255,3,2,4]
["S4482","Palbociclib","d8","L8000-23","in 2mM DMSO","CDK","Cell Cycle","Palbociclib (Ibrance, PD 0332991) is a highly specific inhibitor of cyclin-dependent kinase 4 (Cdk4) and Cdk6 with IC50 of 11 nM and 16 nM, respectively.",447.53,"571190-30-2",{"v":3,"d":"3.00"},{"v":6.7,"d":"6.70"},"<1","N/A","http://www.selleckchem.com/products/palbociclib.html","C24H29N7O2","Free Base","Ibrance, PD 0332991","CC(=O)C1=C(C)C2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2N(C5CCCC5)C1=O",2.801,5,2,5]
["E0524","Spinosad","e8","L8000-23","in 2mM DMSO","AChR,Anti-infection","Neuronal Signaling","Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete, is a biological neurotoxic insecticide with a broader action spectrum, targeting the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system.",731.96,"168316-95-8",{"v":3,"d":"3.00"},{"v":4.1,"d":"4.10"},"<1","N/A","http://www.selleckchem.com/products/spinosad.html","C41H65NO10","free base","N/A","NA","NA","NA","NA","NA"]
["S9464","Tranylcypromine Sulfate","f8","L8000-23","in 2mM DMSO","MAO","Metabolism","Tranylcypromine (Parnate) is an irreversible inhibitor of monoamine oxidase (MAO) with a rapid onset of activity.",364.46,"13492-01-8",{"v":2,"d":"2.00"},5.49,"<1","N/A","http://www.selleckchem.com/products/tranylcypromine-sulfate.html","C18H24N2O4S","Sulfate","Parnate","NC1CC1C2=CC=CC=C2.NC3CC3C4=CC=CC=C4.O[S;v6](O)(=O)=O",{"v":1.78,"d":"1.780"},0,2,2]
["S1911","Disodium Cromoglycate","b2","L8000-24","in 2mM Water","Calcium Channel","Transmembrane Transporters","Disodium Cromoglycate (Gynazole ,FPL 670 (Cromolyn) Disodium,Cromolyn sodium) is an antiallergic drug with IC50 of 39 μg/mL.",512.33,"15826-37-6","<1","N/A",{"v":2,"d":"2.00"},{"v":3.9,"d":"3.90"},"http://selleckchem.com/products/disodium-Cromoglycate.html","C23H14O11.2Na","Disodium Salt","Gynazole ,FPL 670 (Cromolyn) Disodium,Cromolyn sodium","[Na+].[Na+].OC(COC1=C2C(=O)C=C(OC2=CC=C1)C([O-])=O)COC3=CC=CC4=C3C(=O)C=C(O4)C([O-])=O",-1.178,6,1,8]
["S2106","Azasetron HCl","c2","L8000-24","in 2mM Water","5-HT Receptor","Neuronal Signaling","Azasetron HCl (Y-25130) is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.",386.27,"123040-16-4","<1","N/A",{"v":3,"d":"3.00"},7.77,"http://selleckchem.com/products/azasetron-hcl.html","C17H20ClN3O3.HCl","HCl","Y-25130 HCl","Cl.CN1C(=O)COC2=C(C=C(Cl)C=C12)C(=O)NC3CN4CCC3CC4",1.616,3,1,2]
["S2562","Hydralazine HCl","d2","L8000-24","in 2mM Water","Potassium Channel","Transmembrane Transporters","Hydralazine HCl is a hydrochloride salt of hydralazine, which is a direct-acting smooth muscle relaxant used to treat hypertension by acting as a vasodilator primarily in arteries and arterioles.",196.64,"304-20-1","<1","N/A",{"v":1,"d":"1.00"},5.09,"http://selleckchem.com/products/Hydralazine-hydrochloride.html","C8H8N4.HCl","Hydrochloride","N/A","Cl.N/N=C/1NN=CC2=C1C=CC=C2",0.798,2,2,0]
["S4067","Deferiprone","e2","L8000-24","in 2mM Water","Others","Others","Deferiprone (CP20) is a chelating agent with an affinity for ferric ion (iron III)，binds with ferric ions to form neutral 3:1 (deferiprone:iron) complexes that are stable over a wide range of pH values.",139.15,"30652-11-0","<1","N/A",{"v":1,"d":"1.00"},7.19,"http://selleckchem.com/products/deferiprone.html","C7H9NO2","Free Base","CP20","CN1C=CC(=O)C(=C1C)O",-0.139,1,1,0]
["S4226","Minocycline (CL 59806) HCl","f2","L8000-24","in 2mM Water","Antibiotics","Microbiology","Minocycline (CL 59806,Minocin) HCl is the most lipid soluble and most active tetracycline antibiotic, binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis.",493.94,"13614-98-7","<1","N/A",{"v":1,"d":"1.00"},2.02,"http://selleckchem.com/products/minocycline-hcl.html","C23H27N3O7.HCl","Hydrochloride","Minocin","Cl.CN(C)C1C2CC3CC4=C(C(=CC=C4N(C)C)O)C(=O)C3=C(O)C2(O)C(=O)C(=C1O)C(N)=O",{"v":0,"d":"0.000"},0,0,0]
["S4694","Alosetron Hydrochloride","g2","L8000-24","in 2mM Water","5-HT Receptor","Neuronal Signaling","Alosetron Hydrochloride (GR 68755C, GR 68755X, Lotronex) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist.",330.81,"122852-69-1","<1","N/A",{"v":1,"d":"1.00"},3.02,"http://selleckchem.com/products/alosetron-hydrochloride.html","C17H18N4O.HCl","hydrochloride","GR 68755C, GR 68755, GR 68755X, Lotronex, GR-68755, GR68755","Cl.C[N]1C2=C(C(=O)N(CC2)CC3=C(C)N=C[NH]3)C4=C1C=CC=C4",2.036,2,1,2]
["S8030","Plerixafor (AMD3100)","h2","L8000-24","in 2mM Water","CXCR,HIV","GPCR & G Protein","Plerixafor (AMD3100, JM 3100, SID791) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively. Plerixafor inhibits human immunodeficiency virus (HIV) replication.",502.78,"110078-46-1","<1","N/A",{"v":3,"d":"3.00"},5.97,"http://selleckchem.com/products/plerixafor.html","C28H54N8","Free Base","JM 3100, SID791","C1CNCCNCCCN(CCNC1)CC2=CC=C(CN3CCCNCCNCCCNCC3)C=C2",{"v":-0.52,"d":"-0.520"},0,6,4]
["S5650","Sodium Hyaluronate","a3","L8000-24","in 2mM Water","Others","Others","Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan found in various connective tissue of humans.",{"v":401.3,"d":"401.30"},"9067-32-7","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A",{"v":2,"d":"2.00"},"https://www.selleckchem.com/products/sodium-hyaluronate.html","C14H20NNaO11R","free base","N/A","[Na+].CC(=O)NC1C(C(O)C(CO)OC1OC2C(O)C(O)C(O[*])OC2C([O-])=O)[*]",-4.314,5,5,6]
["S2095","Fosinopril Sodium","c3","L8000-24","in 2mM Water","ACE,RAAS","Endocrinology & Hormones","Fosinopril Sodium (SQ28555) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.",585.64,"88889-14-9","N/A","N/A","N/A",{"v":2,"d":"2.00"},"http://selleckchem.com/products/fosinopril-sodium-monopril.html","C30H45NO7P.Na","Sodium Salt","SQ28555","[Na+].CCC(=O)OC(O[P](=O)(CCCCC1=CC=CC=C1)CC(=O)N2CC(CC2C([O-])=O)C3CCCCC3)C(C)C",4.129,5,0,15]