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[820,1,821,1],[820,2,821,2],[822,1,823,1],[822,2,823,2],[824,1,825,1],[824,2,825,2],[826,1,827,1],[826,2,827,2],[828,1,829,1],[828,2,829,2],[833,1,833,13],[835,1,836,1],[835,2,836,2],[835,8,836,8],[835,9,836,9],[835,10,836,10],[837,1,838,1],[837,2,838,2],[837,8,838,8],[837,9,838,9],[837,10,838,10],[839,1,840,1],[839,2,840,2],[839,7,840,7],[839,8,840,8],[839,9,840,9],[839,10,840,10],[841,1,842,1],[841,2,842,2],[841,5,842,5],[841,7,842,7],[841,8,842,8],[841,9,842,9],[841,10,842,10],[843,1,844,1],[843,2,844,2],[843,5,844,5],[843,7,844,7],[843,8,844,8],[843,9,844,9],[843,10,844,10],[845,1,846,1],[845,2,846,2],[845,7,846,7],[845,8,846,8],[845,9,846,9],[845,10,846,10],[847,1,848,1],[847,2,848,2],[847,7,848,7],[847,8,848,8],[847,9,848,9],[847,10,848,10],[849,1,850,1],[849,2,850,2],[849,6,850,6],[849,7,850,7],[849,8,850,8],[849,9,850,9],[849,10,850,10],[854,1,854,13],[856,1,857,1],[856,2,857,2],[858,1,859,1],[858,2,859,2],[860,1,861,1],[860,2,861,2],[862,1,863,1],[862,2,863,2],[864,1,865,1],[864,2,865,2],[866,1,867,1],[866,2,867,2],[868,1,869,1],[868,2,869,2],[870,1,871,1],[870,2,871,2],[875,1,875,13],[877,1,878,1],[877,2,878,2],[877,4,878,4],[877,5,878,5],[877,6,878,6],[877,7,878,7],[877,8,878,8],[877,9,878,9],[877,10,878,10],[879,1,880,1],[879,2,880,2],[879,4,880,4],[879,5,880,5],[879,6,880,6],[879,7,880,7],[879,8,880,8],[879,9,880,9],[879,10,880,10],[881,1,882,1],[881,2,882,2],[881,3,882,3],[881,4,882,4],[881,5,882,5],[881,6,882,6],[881,7,882,7],[881,8,882,8],[881,9,882,9],[881,10,882,10],[883,1,884,1],[883,2,884,2],[883,3,884,3],[883,4,884,4],[883,5,884,5],[883,6,884,6],[883,7,884,7],[883,8,884,8],[883,9,884,9],[883,10,884,10],[885,1,886,1],[885,2,886,2],[885,3,886,3],[885,4,886,4],[885,5,886,5],[885,6,886,6],[885,7,886,7],[885,8,886,8],[885,9,886,9],[885,10,886,10],[887,1,888,1],[887,2,888,2],[887,3,888,3],[887,4,888,4],[887,5,888,5],[887,6,888,6],[887,7,888,7],[887,8,888,8],[887,9,888,9],[887,10,888,10],[889,1,890,1],[889,2,890,2],[889,3,890,3],[889,4,890,4],[889,5,890,5],[889,6,890,6],[889,7,890,7],[889,8,890,8],[889,9,890,9],[889,10,890,10],[891,1,892,1],[891,2,892,2],[891,3,892,3],[891,4,892,4],[891,5,892,5],[891,6,892,6],[891,7,892,7],[891,8,892,8],[891,9,892,9],[891,10,892,10],[896,1,896,13],[898,1,899,1],[898,2,899,2],[898,6,899,6],[898,7,899,7],[898,8,899,8],[898,9,899,9],[898,10,899,10],[900,1,901,1],[900,2,901,2],[900,6,901,6],[900,7,901,7],[900,8,901,8],[900,9,901,9],[902,1,903,1],[902,2,903,2],[902,6,903,6],[902,7,903,7],[902,8,903,8],[902,9,903,9],[904,1,905,1],[904,2,905,2],[904,5,905,5],[904,6,905,6],[904,7,905,7],[904,8,905,8],[904,9,905,9],[906,1,907,1],[906,2,907,2],[906,5,907,5],[906,6,907,6],[906,7,907,7],[906,8,907,8],[906,9,907,9],[908,1,909,1],[908,2,909,2],[908,5,909,5],[908,6,909,6],[908,7,909,7],[908,8,909,8],[908,9,909,9],[910,1,911,1],[910,2,911,2],[910,5,911,5],[910,6,911,6],[910,7,911,7],[910,8,911,8],[910,9,911,9],[912,1,913,1],[912,2,913,2],[912,5,913,5],[912,6,913,6],[912,7,913,7],[912,8,913,8],[912,9,913,9],[917,1,917,13],[919,1,920,1],[919,2,920,2],[919,4,920,4],[919,5,920,5],[919,6,920,6],[919,7,920,7],[919,8,920,8],[919,9,920,9],[921,1,922,1],[921,2,922,2],[921,4,922,4],[921,5,922,5],[921,6,922,6],[921,7,922,7],[921,8,922,8],[921,9,922,9],[923,1,924,1],[923,2,924,2],[923,3,924,3],[923,4,924,4],[923,5,924,5],[923,6,924,6],[923,7,924,7],[923,8,924,8],[923,9,924,9],[925,1,926,1],[925,2,926,2],[925,3,926,3],[925,4,926,4],[925,5,926,5],[925,6,926,6],[925,7,926,7],[925,8,926,8],[925,9,926,9],[927,1,928,1],[927,2,928,2],[927,3,928,3],[927,4,928,4],[927,5,928,5],[927,6,928,6],[927,7,928,7],[927,8,928,8],[927,9,928,9],[929,1,930,1],[929,2,930,2],[929,3,930,3],[929,4,930,4],[929,5,930,5],[929,6,930,6],[929,7,930,7],[929,8,930,8],[929,9,930,9],[931,1,932,1],[931,2,932,2],[931,3,932,3],[931,4,932,4],[931,5,932,5],[931,6,932,6],[931,7,932,7],[931,8,932,8],[931,9,932,9],[933,1,934,1],[933,2,934,2],[933,3,934,3],[933,4,934,4],[933,5,934,5],[933,6,934,6],[933,7,934,7],[933,8,934,8],[933,9,934,9]],"merged_total":1455,"flags":["merged_cut"]}
[{"$nulls":3},"FDA-approved Drug Library  (96-well)-L1300"]
[null,"For more information on Selleck library service, please contact us via +1-832-582-8158 or library@selleckchem.com"]
[]
[null,"Product Details:"]
[null,"Description",null,"A unique collection of 3183 compounds"]
[null,"Container",null,"96 Well"]
[null,"Stability",null,"12 months | ﹣20°C | in DMSO"]
[{"$nulls":3},"24 months | ﹣80°C | in DMSO"]
[null,"Shipping",null,"Blue ice or Dry ice"]
[null,"Formulation",null,"Solubility ≥10 mM pre-dissolved in 10 mM solution and solubility between 2 mM and 10 mM pre-dissolved in 2 mM solution"]
[{"$nulls":3},"In 10 mM DMSO : Plate layout L1300-1~36;    In 10 mM Water: Plate layout L1300-37~40;"]
[{"$nulls":3},"In 2 mM DMSO : Plate layout L1300-41~42;    In 2 mM Water  : Plate layout L1300-43"]
[{"$nulls":3},"In 2mg/ml DMSO: Plate layout L1300-44"]
[]
[null,"Plate layout: L1300-01"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1005","S1022","S1039","S1064","S1144","S1183","S1196","S1208","S1222","S1237","Empty"]
[{"$nulls":3},"Axitinib (AG 013736)","Ridaforolimus (Deforolimus, MK-8669)","Rapamycin (AY-22989)","Masitinib (AB1010)","Ivacaftor (VX-770)","Danoprevir (ITMN-191)","Exemestane (FCE 24304)","Doxorubicin (Adriamycin) HCl","Dexrazoxane HCl (ICRF-187)","Temozolomide (CCRG 81045)"]
[null,"b","Empty","S1007","S1025","S1040","S1068","S1148","S1185","S1197","S1209","S1223","S1238","Empty"]
[{"$nulls":3},"Roxadustat (FG-4592)","Gefitinib (ZD1839)","Sorafenib (BAY 43-9006) tosylate","Crizotinib (PF-02341066)","Docetaxel (RP56976)","Ritonavir (ABT-538)","Finasteride","Fluorouracil (5-Fluorouracil, 5-FU)","Epirubicin (IMI 28) HCl","Tamoxifen (ICI 46474)"]
[null,"c","Empty","S1008","S1026","S1042","S1082","S1150","S1188","S1199","S1210","S1225","S1241","Empty"]
[{"$nulls":3},"Selumetinib (AZD6244)","Imatinib (STI571) Mesylate","Sunitinib (SU11248) malate","Vismodegib (GDC-0449)","Paclitaxel (NSC 125973)","Anastrozole (ZD-1033)","Cladribine (RWJ 26251)","Methotrexate (CL-14377)","Etoposide (VP-16)","Vincristine (NSC-67574) sulfate"]
[null,"d","Empty","S1010","S1028","S1044","S1085","S1156","S1189","S1200","S1212","S1227","S1243","Empty"]
[{"$nulls":3},"Nintedanib (BIBF 1120)","Lapatinib (GW-572016) Ditosylate","Temsirolimus (CCI-779)","Belinostat (PXD101)","Capecitabine (RO 09-1978)","Aprepitant (MK-0869)","Decitabine (NSC 127716)","Bendamustine (SDX105) HCl","Raloxifene HCl","Agomelatine (S20098)"]
[null,"e","Empty","S1011","S1029","S1047","S1098","S1162","S1190","S1202","S1213","S1229","S1245","Empty"]
[{"$nulls":3},"Afatinib (BIBW2992)","Lenalidomide (CC-5013)","Vorinostat (SAHA)","Rucaparib (AG-014699) phosphate","Pretomanid (PA-824)","Bicalutamide (ICI-176334)","Dutasteride","Nelarabine","Fludarabine Phosphate","Latrepirdine 2HCl"]
[null,"f","Empty","S1013","S1030","S1053","S1119","S1164","S1191","S1204","S1214","S1231","S1247","Empty"]
[{"$nulls":3},"Bortezomib (PS-341)","Panobinostat (LBH589)","Entinostat (MS-275)","Cabozantinib (BMS-907351)","Lenvatinib (E7080)","Fulvestrant (ICI-182780)","Melatonin (NSC 113928)","Bleomycin (NSC125066) sulfate","Topotecan (NSC609699) HCl","Leflunomide (HWA486)"]
[null,"g","Empty","S1014","S1033","S1055","S1120","S1168","S1192","S1206","S1218","S1233","S1250","Empty"]
[{"$nulls":3},"Bosutinib (SKI-606)","Nilotinib (AMN-107)","Enzastaurin (LY317615)","Everolimus (RAD001)","Valproic Acid (NSC 93819) sodium salt","Raltitrexed","Bisoprolol fumarate","Clofarabine","2-Methoxyestradiol (2-MeOE2)","Enzalutamide (MDV3100)"]
[null,"h","Empty","S1021","S1035","S1060","S1137","S1178","S1193","S1207","S1221","S1235","S1251","Empty"]
[{"$nulls":3},"Dasatinib (BMS-354825)","Pazopanib HCl (GW786034 HCl)","Olaparib (AZD2281)","Malotilate","Regorafenib (BAY 73-4506)","Thalidomide (K17)","Tivozanib (AV-951)","Dacarbazine (NSC-45388)","Letrozole (CGS 20267)","Dienogest"]
[]
[]
[]
[null,"Plate layout: L1300-02"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1252","S1267","S1284","S1300","S1328","S1342","S1367","S1380","S1391","S1403","Empty"]
[{"$nulls":3},"Entecavir Hydrate","Vemurafenib (PLX4032)","Benazepril HCl","Tegafur (FT-207)","Etodolac","Genistein (NPI 031L)","Amonafide","Lopinavir (ABT-378)","Oxcarbazepine","Tigecycline (GAR-936)"]
[null,"b","Empty","S1255","S1271","S1286","S1302","S1330","S1344","S1368","S1381","S1393","S1404","Empty"]
[{"$nulls":3},"Nepafenac","Acarbose","Budesonide","Ifosfamide (NSC109724)","Felbamate","Glimepiride","Acitretin","Meropenem","Pirarubicin (NSC-333054)","Trilostane"]
[null,"c","Empty","S1256","S1276","S1287","S1304","S1331","S1351","S1373","S1382","S1394","S1405","Empty"]
[{"$nulls":3},"Rufinamide","Adapalene","Bumetanide","Megestrol Acetate","Fluconazole (UK 49858)","Ivermectin (MK-933)","Daptomycin (LY146032)","Mianserin HCl","Pizotifen Malate","Vecuronium Bromide"]
[null,"d","Empty","S1257","S1278","S1289","S1305","S1332","S1354","S1374","S1385","S1396","S1407","Empty"]
[{"$nulls":3},"Posaconazole (SCH 56592)","Altretamine","Carmofur","Mercaptopurine (6-MP)","Flumazenil (RO 15-1788)","Lansoprazole","Doripenem Hydrate","Mosapride Citrate","Resveratrol (SRT501)","Bimatoprost"]
[null,"e","Empty","S1258","S1280","S1291","S1319","S1333","S1356","S1376","S1386","S1397","S1408","Empty"]
[{"$nulls":3},"Prasugrel","Amisulpride","Cetirizine DiHCl","Costunolide","Fluoxetine (Lilly 110140) HCl","Levetiracetam (UCB-L059)","Gestodene","Nafamostat mesilate (FUT-175)","Rocuronium Bromide","Linezolid (PNU-100766)"]
[null,"f","Empty","S1259","S1281","S1293","S1322","S1334","S1357","S1377","S1387","S1398","S1409","Empty"]
[{"$nulls":3},"Ramelteon","Aniracetam","Cilnidipine (FRC-8653)","Dexamethasone (MK-125)","Flupirtine maleate","Lidocaine","Drospirenone","Naftopidil DiHCl","Stavudine (d4T)","Alfuzosin HCl"]
[null,"g","Empty","S1260","S1282","S1294","S1324","S1336","S1358","S1378","S1389","S1400","S1415","Empty"]
[{"$nulls":3},"Cinacalcet (AMG-073) HCl","Artemisinin","Cilostazol (OPC-13013)","Doxazosin Mesylate","Fluvoxamine (DU-23000) maleate","Loratadine (SCH29851)","Ruxolitinib (INCB018424)","Omeprazole","Tenofovir (GS 1278) Disoproxil Fumarate","Clopidogrel (SR-25990C) Bisulfate"]
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[{"$nulls":3},"Celecoxib (SC 58635)","Asenapine maleate","Floxuridine (NSC 27640)","Edaravone","Gatifloxacin","Losartan Potassium (DuP 753)","Isotretinoin","Ondansetron HCl","Tenofovir","Ranolazine 2HCl"]
[]
[]
[]
[null,"Plate layout: L1300-03"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1426","S1441","S1465","S1490","S1508","S1547","S1573","S1605","S1614","S1628","Empty"]
[{"$nulls":3},"Repaglinide","Venlafaxine HCl","Moxifloxacin (BAY12-8039) HCl","Ponatinib (AP24534)","Alprostadil","Febuxostat","Fasudil (HA-1077) HCl","Cefdinir","Riluzole (PK 26124)","Triamcinolone Acetonide"]
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[{"$nulls":3},"Rolipram (ZK-62711)","Voriconazole (UK-109496)","Doxercalciferol","Fludarabine (NSC 118218)","Lactulose","Dapagliflozin (BMS-512148)","Sulfasalazine (NSC 667219)","Clotrimazole","Sulfameter","Orlistat (Ro 18-0647)"]
[null,"c","Empty","S1431","S1443","S1468","S1497","S1512","S1549","S1578","S1607","S1619","S1630","Empty"]
[{"$nulls":3},"Sildenafil Citrate","Zileuton (A-64077)","Alfacalcidol","Pralatrexate (NSC 754230)","Tadalafil (IC351)","Nebivolol hydrochloride (R-65824)","Candesartan (CV-11974)","Rizatriptan Benzoate","Prilocaine","Allopurinol"]
[null,"d","Empty","S1432","S1444","S1472","S1499","S1514","S1550","S1591","S1608","S1620","S1631","Empty"]
[{"$nulls":3},"Sumatriptan Succinate","Ziprasidone HCl","Safinamide Mesylate","Cefaclor","Cyclosporine","Pimobendan","Bestatin (NK421)","Pyridostigmine Bromide","Darunavir Ethanolate","Allopurinol Sodium"]
[null,"e","Empty","S1435","S1445","S1482","S1500","S1517","S1553","S1593","S1609","S1622","S1633","Empty"]
[{"$nulls":3},"Tamsulosin hydrochloride","Zonisamide","Daclatasvir (BMS-790052)","Betamethasone","Natamycin","Delafloxacin (ABT-492)","Apixaban (BMS 562247-01)","Methimazole","Prednisone (NSC-10023)","Zafirlukast (ICI-204219)"]
[null,"f","Empty","S1437","S1453","S1483","S1501","S1526","S1565","S1601","S1610","S1625","S1635","Empty"]
[{"$nulls":3},"Tizanidine HCl","Tipifarnib (R115777)","Iloperidone","Mycophenolate mofetil (RS-61443)","Quizartinib (AC220)","Lumacaftor (VX-809)","Reserpine","Metolazone","Ethinyl Estradiol","Erythromycin"]
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[{"$nulls":3},"Topiramate","Atazanavir (BMS-232632) Sulfate","HMN-214","Dyphylline","Telaprevir (VX-950)","Pomalidomide (CC-4047)","Furosemide (NSC 269420)","Cefoperazone","Naproxen Sodium","Amphotericin B"]
[null,"h","Empty","S1439","S1458","S1488","S1505","S1540","S1569","S1604","S1613","S1627","S1638","Empty"]
[{"$nulls":3},"Tranilast (SB 252218)","Neflamapimod (VX-745)","Naratriptan HCl","Aztreonam","Saxagliptin (BMS-477118)","Tazarotene","Olmesartan Medoxomil","Silodosin","Nitazoxanide (NSC 697855)","Ibuprofen (NSC 256857)"]
[]
[]
[]
[null,"Plate layout: L1300-04"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
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[{"$nulls":3},"Amprenavir (VX-478)","Zolmitriptan","Isradipine","Chloramphenicol","Betamethasone Valerate","Emtricitabine (BW 1592)","Glyburide (Glibenclamide)","Gemfibrozil","Telmisartan","Nisoldipine"]
[null,"b","Empty","S1640","S1651","S1665","S1679","S1691","S1705","S1717","S1730","S1739","S1750","Empty"]
[{"$nulls":3},"Albendazole (SKF-62979)","Telbivudine","Estrone","Flurbiprofen","Praziquantel","Progesterone (NSC 9704)","Fomepizole","Indapamide","Thiabendazole","Octocrylene"]
[null,"c","Empty","S1641","S1652","S1666","S1680","S1692","S1706","S1718","S1732","S1740","S1754","Empty"]
[{"$nulls":3},"Chlorothiazide","Monobenzone","Flucytosine","Disulfiram (NSC 190940)","Busulfan (NSC-750)","Lamivudine (BCH-189)","Adefovir Dipivoxil (GS 0840)","Mitotane","Guaifenesin","Oxybutynin"]
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[{"$nulls":3},"Ursodiol","Tretinoin (NSC 122758)","Trichlormethiazide","Mesalamine (5-ASA)","Carbamazepine","Estradiol","Zalcitabine","Methylprednisolone (NSC-19987)","Rifabutin (LM427)","Enoxacin"]
[null,"e","Empty","S1644","S1654","S1669","S1683","S1696","S1712","S1721","S1734","S1742","S1759","Empty"]
[{"$nulls":3},"Nitrofural","Phenylbutazone","Loteprednol etabonate","Ipratropium Bromide","Hydrocortisone (NSC 10483)","Deferasirox (ICL-670)","Azathioprine","Meloxicam","Nevirapine (NSC 641530)","Pitavastatin (NK-104) calcium"]
[null,"f","Empty","S1645","S1655","S1673","S1685","S1701","S1713","S1723","S1735","S1743","S1760","Empty"]
[{"$nulls":3},"Ketoprofen","Ezetimibe (SCH-58235)","Aminophylline","Sulfanilamide","Desonide","Piroxicam","Indomethacin (NSC-77541)","Mesna","Esomeprazole magnesium","Rifapentine"]
[null,"g","Empty","S1646","S1657","S1675","S1688","S1702","S1714","S1725","S1736","S1744","S1761","Empty"]
[{"$nulls":3},"Ketorolac","Enalaprilat Dihydrate","Lubiprostone","Betamethasone Dipropionate","Didanosine","Gemcitabine (LY-188011)","Terbinafine","Methocarbamol","Nicotinic Acid","Suprofen"]
[null,"h","Empty","S1647","S1658","S1676","S1689","S1703","S1715","S1727","S1737","S1747","S1762","Empty"]
[{"$nulls":3},"Adenosine","Dofetilide","Amorolfine HCl","Meprednisone","Divalproex Sodium","Glipizide","Levonorgestrel","Prednisolone (NSC-9900)","Nimodipine","Pyrazinamide"]
[]
[]
[]
[null,"Plate layout: L1300-05"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1763","S1776","S1790","S1806","S1825","S1835","S1849","S1869","S1888","S1899","Empty"]
[{"$nulls":3},"Quetiapine (ICI-204636) fumarate","Toremifene Citrate (NK 622)","Rifaximin","Acipimox","Erdosteine","Azithromycin (CP-62993)","Daidzein","Dapoxetine HCl","Deflazacort","Nicotinamide (NSC 13128)"]
[null,"b","Empty","S1764","S1777","S1791","S1807","S1827","S1836","S1854","S1876","S1890","S1902","Empty"]
[{"$nulls":3},"Rifampin (NSC-113926)","Ethionamide","Bacitracin Zinc","Aciclovir (BW 248U)","Betaxolol HCl","Albendazole Oxide","Bifonazole","Valaciclovir HCl","Nizatidine","Vitamin B12"]
[null,"c","Empty","S1768","S1778","S1792","S1808","S1828","S1839","S1855","S1878","S1891","S1903","Empty"]
[{"$nulls":3},"Cefditoren Pivoxil","Trifluridine (NSC 75520)","Simvastatin (MK 733)","Nifedipine (BAY-a-1040)","Proparacaine HCl","Chloroxine","Pefloxacin Mesylate","Ganciclovir (BW 759)","Carbidopa","Diclofenac Sodium"]
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[{"$nulls":3},"Sulfadiazine","Azacitidine (5-Azacytidine)","Ramipril","Amiloride (MK-870) HCl","Pranlukast","Lomustine","Metoprolol Tartrate","Roxatidine Acetate HCl","Valsartan (CGP-48933)","Avobenzone"]
[null,"e","Empty","S1771","S1784","S1794","S1813","S1830","S1843","S1858","S1881","S1895","S1905","Empty"]
[{"$nulls":3},"Chlorprothixene","Vidarabine","Fenofibrate (NSC-281319)","Amlodipine Besylate","Oxfendazole","Chenodeoxycholic Acid","Dienestrol","Protionamide","Dipyridamole (NSC 515776)","Amlodipine"]
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[{"$nulls":3},"Oxytetracycline (Terramycin)","Verteporfin (CL 318952)","Ranolazine","Chlorpheniramine Maleate","Carvedilol","Cimetidine","Diethylstilbestrol","Idoxuridine","Hydroxyurea (NSC-32065)","Metronidazole"]
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[{"$nulls":3},"Thioguanine (NSC 752)","Teniposide","Ranitidine Hydrochloride","Clofibrate","Atracurium Besylate","Clemastine (HS-592) fumarate","Diltiazem HCl","Sparfloxacin","Potassium Iodide","Flutamide"]
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[{"$nulls":3},"Thiotepa","Tetrabenazine (Xenazine)","Acetylcholine Chloride","Fenoprofen Calcium","Butoconazole nitrate","Curcumin","Diphenhydramine HCl","Felodipine","Tropisetron HCl","Fluvastatin (XU-62-320) Sodium"]
[]
[]
[]
[null,"Plate layout: L1300-06"]
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[{"$nulls":3},"Tioconazole","Alibendol","Methoxsalen","Primidone","Amiodarone (NSC 85442) HCl","Maraviroc (UK-427857)","Formoterol Hemifumarate","Rebamipide","Cyproheptadine HCl","Cyclophosphamide (NSC-26271) Monohydrate"]
[null,"b","Empty","S1913","S1933","S1956","S1969","S1983","S2005","S2021","S2036","S2045","S2058","Empty"]
[{"$nulls":3},"Tropicamide","Triamcinolone","Miconazole Nitrate","Nefiracetam","Adenine HCl","Raltegravir (MK-0518)","Chlormezanone","Aspartame","Doxifluridine","Tolnaftate"]
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[{"$nulls":3},"Pregnenolone","Nystatin (Fungicidin)","Sulfamethizole","Nicorandil","Mometasone furoate","Pyrimethamine","Ketotifen Fumarate","Candesartan Cilexetil","Pioglitazone HCl","Terazosin HCl Dihydrate"]
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[{"$nulls":3},"Sulfamethoxazole","Isoniazid","Sulbactam","Tamoxifen (ICI 46474) Citrate","Propylthiouracil","Sulindac","Urapidil HCl","Phentolamine Mesylate","Captopril","Bromhexine HCl"]
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[{"$nulls":3},"Sulfisoxazole","Levofloxacin","Tolfenamic Acid","Cyclocytidine HCl","Capsaicin(Vanilloid)","Pramipexole 2HCl Monohydrate","Diclazuril","Nimesulide","Oxytetracycline Dihydrate","Lovastatin (MK-803)"]
[null,"f","Empty","S1917","S1941","S1960","S1974","S1992","S2015","S2029","S2041","S2053","S2062","Empty"]
[{"$nulls":3},"Crystal Violet","Enalapril Maleate","Pranoprofen","Meglumine","Fluticasone propionate","Suplatast Tosylate","Uridine","Dyclonine HCl","Cytidine","Tiopronin"]
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[{"$nulls":3},"Haloperidol","Menadione (NSC 4170)","Sulphadimethoxine","Aripiprazole","Lacidipine","Mirtazapine","Flunarizine 2HCl","Cyproterone Acetate","Orphenadrine Citrate","Balofloxacin"]
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[{"$nulls":3},"Phenindione","Metformin HCl","Rimantadine","Methscopolamine","Elvitegravir (JTK-303)","Benidipine HCl","Fenticonazole Nitrate","Memantine HCl","Gimeracil","Lafutidine"]
[]
[]
[]
[null,"Plate layout: L1300-07"]
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[{"$nulls":3},"Moxonidine","Moexipril HCl","Dexmedetomidine HCl","Rasagiline Mesylate","Dronedarone HCl","Naftopidil","Bazedoxifene (TSE-424) acetate","Aliskiren Hemifumarate","(-)-Epigallocatechin Gallate","Artesunate (WR-256283)"]
[null,"b","Empty","S2067","S2080","S2091","S2103","S2116","S2127","S2169","Empty","S2256","S2266","Empty"]
[{"$nulls":3},"Ozagrel HCl","Clevidipine Butyrate","Betaxolol","Naltrexone HCl","Conivaptan HCl","S-(+)-Rolipram","Rosuvastatin (ZD4522) calcium",null,"4-Methylumbelliferone (4-MU)","Asiatic Acid"]
[null,"c","Empty","S2069","S2082","S2092","S2104","S2118","S2128","S2173","S2217","S2258","S2268","Empty"]
[{"$nulls":3},"Argatroban (MCI-9038)","Adiphenine HCl","Detomidine HCl","Levosulpiride","Ibutilide Fumarate","Bazedoxifene (WAY-140424) HCl","Telotristat Etiprate (LX 1606 Hippurate)","Irinotecan (CPT-11) HCl Trihydrate","Esculin","Baicalein"]
[null,"d","Empty","S2071","S2083","S2096","S2105","S2119","S2130","S2177","S2219","S2260","S2269","Empty"]
[{"$nulls":3},"Prulifloxacin (NM441)","Procaterol HCl","Almotriptan Malate","Pantoprazole","Probucol","Atropine sulfate monohydrate","Dichlorphenamide","Momelotinib (CYT387)","Amygdalin","Baicalin (NSC-661431)"]
[null,"e","Empty","S2072","S2084","S2097","S2108","S2120","S2131","S2180","S2226","S2261","S2270","Empty"]
[{"$nulls":3},"Seratrodast(AA-2414)","Duloxetine HCl","Ambrisentan","Flunixin Meglumin","Arbidol HCl","Roflumilast (B9302-107)","Ixazomib (MLN2238)","Idelalisib","Andrographolide","Bergenin"]
[null,"f","Empty","S2075","S2085","S2098","S2109","S2123","S2151","S2181","S2229","S2262","S2271","Empty"]
[{"$nulls":3},"Rosiglitazone (BRL-49653) HCl","Trimebutine","Bexarotene (LGD1069)","Imidapril HCl","Dextrose","Sonidegib (NVP-LDE225)","Ixazomib Citrate (MLN9708) Analogue","Eltrombopag (SB497115) Olamine","Apigenin (LY 080400)","Berberine chloride (NSC 646666)"]
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[{"$nulls":3},"Atorvastatin Calcium","Ivabradine HCl","Temocapril HCl","Lapatinib (GW-572016)","Xylose","Dabigatran (BIBR-1048) etexilate","Infigratinib (BGJ398)","Esomeprazole sodium","Arbutin","Caffeic Acid"]
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[{"$nulls":3},"Famotidine","Rivastigmine Tartrate","Gabexate Mesylate","Cisatracurium Besylate","Mestranol","Tebipenem Pivoxil","Phenprocoumon","Abiraterone Acetate (CB7630)","Artemether","Chlorogenic Acid"]
[]
[]
[]
[null,"Plate layout: L1300-08"]
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[{"$nulls":3},"Cinchonidine","Emodin","Hesperidin","Magnolol","Orotic acid (6-Carboxyuracil)","Rotenone (Barbasco)","Synephrine","Aloin","Hematoxylin","Salidroside"]
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[{"$nulls":3},"Cinchonine(LA40221)","Enoxolone","Honokiol (NSC 293100)","(+)-Matrine","Osthole","Rutaecarpine","Tanshinone I","Ammonium Glycyrrhizinate","Indirubin (NSC 105327)","Palmatine chloride"]
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[{"$nulls":3},"Colchicine (NSC 757)","Formononetin","Hyodeoxycholic acid (HDCA)","Morin Hydrate","Oxymatrine","Rutin","Tanshinone IIA","Butylscopolamine Bromide","Lappaconite HBr","Sodium Danshensu"]
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[{"$nulls":3},"Cyclosporin A (NSC 290193)","Ferulic Acid","Kaempferol (NSC 407289)","Nalidixic acid","Paeonol","Salicin","Taxifolin (Dihydroquercetin)","Dioscin","L-carnitine","Tetrandrine (NSC-77037)"]
[null,"e","Empty","S2287","S2302","S2316","S2329","S2341","S2354","S2369","S2380","S2389","Empty","Empty"]
[{"$nulls":3},"Cytisine","Glycyrrhizin (NSC 167409)","Kinetin","Naringin","(-)-Parthenolide","Sclareol","Troxerutin","Diosmetin","Naringin Dihydrochalcone"]
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[{"$nulls":3},"Daidzin","Gossypol Acetate","L-(+)-Rhamnose Monohydrate","Neohesperidin Dihydrochalcone (Nhdc)","Piperine","Silibinin (NSC 651520)","Ursolic Acid","D-Mannitol","Polydatin","Paeoniflorin (NSC 178886)"]
[null,"g","Empty","S2290","S2304","S2318","S2332","S2346","S2358","S2373","S2382","S2391","S2411","Empty"]
[{"$nulls":3},"Dihydroartemisinin (DHA)","Gramine","Lappaconitine","Neohesperidin","Puerarin","Silymarin","Yohimbine HCl","Evodiamine","Quercetin (NSC 9221)","Geniposide"]
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[{"$nulls":3},"DL-Carnitine HCl","Hesperetin","Luteolin","Oleanolic Acid","Quercetin Dihydrate","Sinomenine","5-hydroxytryptophan (5-HTP)","Gastrodin","Sorbitol","Ipriflavone (Osteofix)"]
[]
[]
[]
[null,"Plate layout: L1300-09"]
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[{"$nulls":3},"(S)-10-Hydroxycamptothecin","Amantadine HCl","Pramipexole","Imatinib (STI571)","Mycophenolic acid","Phenoxybenzamine HCl","Scopolamine (LSM-4015) HBr","Naphazoline HCl","Isoconazole nitrate","Trospium chloride"]
[null,"b","Empty","S2437","S2452","S2461","S2479","S2489","S2500","S2509","S2521","S2535","S2551","Empty"]
[{"$nulls":3},"Rotundine","Amfebutamone (Bupropion) HCl","Domperidone","Lincomycin HCl","Nateglinide","Propafenone HCl","Sotalol HCl","Epinephrine bitartrate","Econazole nitrate","Sulbactam sodium"]
[null,"c","Empty","S2438","S2454","S2466","S2480","S2491","S2501","S2510","S2524","S2536","S2552","Empty"]
[{"$nulls":3},"Synephrine HCl","Bupivacaine HCl","Estriol","Loperamide HCl","Nitrendipine","Pyrantel Pamoate","Spectinomycin 2HCl","Phenytoin Sodium","Miconazole","Azelastine HCl"]
[null,"d","Empty","S2439","S2455","S2467","S2481","S2492","S2502","S2511","S2525","S2537","S2553","Empty"]
[{"$nulls":3},"Guanosine","Bethanechol chloride","Famciclovir","Manidipine","Novobiocin Sodium (NSC 2382)","Quinine HCl Dihydrate","Sulfadoxine","Phenytoin","Secnidazole","5-Aminolevulinic acid HCl"]
[null,"e","Empty","S2442","S2456","S2468","S2482","S2493","S2503","S2512","S2528","S2541","S2554","Empty"]
[{"$nulls":3},"Inosine","Chlorpromazine HCl","Fenbendazole","Manidipine 2HCl","Olanzapine","Racecadotril","Tenoxicam","Ciclopirox","Clomipramine HCl","Daphnetin"]
[null,"f","Empty","S2443","S2457","S2470","S2484","S2494","S2504","S2515","S2529","Empty","S2555","Empty"]
[{"$nulls":3},"Tolbutamide (HLS 831)","Clindamycin HCl","Fluocinolone Acetonide","Milrinone","Olopatadine HCl","Ribavirin (ICN-1229)","Vardenafil HCl Trihydrate","Dopamine HCl",null,"Clarithromycin"]
[null,"g","Empty","S2446","S2458","S2471","S2485","S2496","S2505","S2516","S2532","S2543","S2556","Empty"]
[{"$nulls":3},"Levosimendan","Clonidine HCl","Gallamine Triethiodide","Mitoxantrone (NSC-301739) 2HCl","Ozagrel","Rosiglitazone (BRL-49653) maleate","Xylazine HCl","L-Ascorbyl 6-palmitate","Ceftiofur HCl","Rosiglitazone (BRL 49653)"]
[null,"h","Empty","S2450","S2459","S2473","S2486","S2497","S2506","S2517","S2533","S2547","S2557","Empty"]
[{"$nulls":3},"Equol","Clozapine","Hexestrol","Moroxydine HCl","Pancuronium dibromide","Roxithromycin","Maprotiline HCl","Ritodrine HCl","Tiotropium Bromide hydrate","Terbinafine HCl"]
[]
[]
[]
[null,"Plate layout: L1300-10"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S2559","S2573","S2585","S2601","S2610","S2667","S2760","S2797","S2868","S2907","Empty"]
[{"$nulls":3},"Cortisone acetate","Tetracaine HCl","Brompheniramine hydrogen maleate","Gliclazide","Lonidamine (AF-1890)","Dolutegravir (GSK1349572)","Canagliflozin (JNJ 28431754)","Lonafarnib (SCH66336)","Alogliptin (SYR-322) benzoate","Pirfenidone (S-7701)"]
[null,"b","Empty","S2561","S2574","S2586","S2602","S2611","S2673","S2762","S2807","S2874","S2922","Empty"]
[{"$nulls":3},"Clomifene citrate","Tetracycline HCl","Dimethyl Fumarate","Acemetacin","Ethisterone","Trametinib (GSK1120212)","Alectinib (CH5424802)","Dabrafenib (GSK2118436)","Camostat Mesilate","Icotinib (BPI-2009H)"]
[null,"c","Empty","S2564","S2576","S2589","S2603","S2613","S2680","S2765","S2809","S2875","S3000","Empty"]
[{"$nulls":3},"Cloxacillin Sodium","Xylometazoline HCl","Miglitol","Tioxolone","Clorsulon","Ibrutinib (PCI-32765)","MK-2048","MPEP","Prucalopride","Carbazochrome sodium sulfonate (AC-17)"]
[null,"d","Empty","S2565","S2577","S2590","S2605","S2614","S2700","S2787","S2814","S2883","S3001","Empty"]
[{"$nulls":3},"Amoxicillin Sodium","Phenacetin","Pioglitazone (AD-4833)","Idebenone","Arecoline HBr","Tirbanibulin","Laquinimod","Alpelisib (BYL719)","4-Aminohippuric Acid","Clevudine"]
[null,"e","Empty","S2566","S2579","S2593","S2606","S2615","S2721","S2789","S2830","S2884","S3002","Empty"]
[{"$nulls":3},"Isoprenaline (NCI-C55630) HCl","Zidovudine","Tolvaptan","Mifepristone (RU486)","Noradrenaline bitartrate monohydrate","Nilvadipine","Tofacitinib (CP-690550)","Clindamycin","Acesulfame Potassium","Rivaroxaban (BAY 59-7939)"]
[null,"f","Empty","S2567","S2581","S2594","S2607","S2625","S2727","S2790","S2840","S2900","S3003","Empty"]
[{"$nulls":3},"Medroxyprogesterone acetate (NSC-26386)","Quinapril HCl","Pramiracetam","Buflomedil HCl","Fostamatinib (R788)","Dacomitinib (PF-00299804)","Istradefylline","Apalutamide (ARN-509)","Cobicistat (GS-9350)","Prostaglandin E2 (PGE2)"]
[null,"g","Empty","S2569","S2583","S2596","S2608","S2664","S2736","S2792","S2851","S2902","S3005","Empty"]
[{"$nulls":3},"Phenylephrine (NCI-C55641) HCl","Thiamphenicol","Clindamycin palmitate HCl","Fluocinonide","Clinofibrate","Fedratinib (TG101348)","Torcetrapib","Baricitinib (INCB028050)","S-Ruxolitinib (INCB018424)","Paroxetine HCl"]
[null,"h","Empty","S2570","S2584","S2599","S2609","S2665","S2741","S2794","S2853","S2903","S3008","Empty"]
[{"$nulls":3},"Prednisolone Acetate","Clobetasol propionate","L-Thyroxine","Inulin","Ciprofibrate","Niraparib (MK-4827)","Sofosbuvir (GS-7977)","Carfilzomib (PR-171)","Lumiracoxib","Zaltoprofen"]
[]
[]
[]
[null,"Plate layout: L1300-11"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S3012","S3024","S3038","S3054","S3070","S3083","S3117","S3137","S3153","S3170","Empty"]
[{"$nulls":3},"Pazopanib","Lamotrigine","Fosaprepitant dimeglumine salt","Alverine Citrate","Piracetam","Indacaterol Maleate","Oxybutynin hydrochloride","Sodium salicylate","Levalbuterol tartrate","Ampicillin sodium"]
[null,"b","Empty","S3015","S3027","S3043","S3057","S3071","S3100","S3120","S3138","S3154","S3172","Empty"]
[{"$nulls":3},"Amoxicillin","Fenoprofen calcium hydrate","Rofecoxib","Azilsartan Medoxomil","Vanillin","2-Thiouracil","Doxepin HCl","Methylthiouracil","Butenafine HCl","Anagrelide HCl"]
[null,"c","Empty","S3017","S3030","S3045","S3060","S3074","S3104","S3121","S3140","S3155","S3173","Empty"]
[{"$nulls":3},"Aspirin (NSC 27223)","Niclosamide (BAY2353)","Cinepazide maleate","Medetomidine HCl","Chlorthalidone","Moguisteine","Ornidazole","Milnacipran HCl","Mepivacaine HCl","Antipyrine"]
[null,"d","Empty","S3018","S3031","S3046","S3061","S3077","S3105","S3124","S3144","S3160","S3175","Empty"]
[{"$nulls":3},"Niflumic acid","Linagliptin (BI-1356)","Azilsartan","Epinephrine HCl","Tazobactam","Nadifloxacin","Dexamethasone Acetate","Darifenacin HBr","Ethynodiol diacetate","Atomoxetine HCl"]
[null,"e","Empty","S3019","S3033","S3047","S3062","S3078","S3106","S3129","S3147","S3161","S3176","Empty"]
[{"$nulls":3},"Ciclopirox ethanolamine","Vildagliptin (LAF-237)","Otilonium Bromide","Diclofenac Potassium","Beclomethasone dipropionate","Pidotimod","Trimethoprim","Entacapone","Sertaconazole nitrate","Betahistine 2HCl"]
[null,"f","Empty","S3021","S3035","S3051","S3063","S3079","S3113","S3130","S3149","S3162","S3178","Empty"]
[{"$nulls":3},"Rimonabant (SR141716)","Daunorubicin (RP 13057) HCl","Bosentan Hydrate","Diclofenac Diethylamine","Atovaquone","Pyridoxine HCl","Biotin (Vitamin B7)","Estradiol valerate","Tylosin tartrate","Brinzolamide"]
[null,"g","Empty","S3022","S3036","S3052","S3066","S3080","S3114","S3132","S3150","S3163","S3179","Empty"]
[{"$nulls":3},"Cabazitaxel (XRP6258)","Pravastatin sodium","Rupatadine Fumarate","Naloxone HCl","Etravirine (TMC125)","Vitamin C","Sulfamerazine","Articaine HCl","Benztropine mesylate","Carbenicillin disodium"]
[null,"h","Empty","S3023","S3037","S3053","S3067","S3081","S3116","S3133","S3151","S3167","S3180","Empty"]
[{"$nulls":3},"Bufexamac","Bepotastine Besilate","Azelnidipine","Chlorhexidine 2HCl","Ulipristal Acetate (CDB 2914)","Sulfathiazole","Sulfamethazine","Gliquidone","Altrenogest","Eletriptan HBr"]
[]
[]
[]
[null,"Plate layout: L1300-12"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S3181","S3200","S3609","S3623","S3641","S3656","S3672","S3687","S3701","S3711","Empty"]
[{"$nulls":3},"Flumequine","Triflusal","Berbamine dihydrochloride","Ceftibuten dihydrate","Osalmid","Piribedil","Cefonicid sodium","Urea","Benactyzine hydrochloride","Carbasalate Calcium"]
[null,"b","Empty","S3183","S3201","S3611","S3625","S3643","S3657","S3673","S3689","S3703","S3713","Empty"]
[{"$nulls":3},"Amitriptyline HCl","Trifluoperazine 2HCl","(+)-Fangchinoline","Tyramine","Amitraz","Promestriene","Sulfaphenazole","Ethidium bromide","Phenethyl alcohol","Moxidectin"]
[null,"c","Empty","S3185","Empty","S3612","S3627","S3644","S3659","S3674","S3690","S3704","S3714","Empty"]
[{"$nulls":3},"Adrenalone HCl",null,"Rosmarinic acid","Tryptamine","Sulfamonomethoxine","Fludrocortisone acetate","Levamlodipine","Pargyline hydrochloride","4-Methylbenzylidene camphor","Lifitegrast"]
[null,"d","Empty","S3186","S3207","S3615","S3635","S3645","S3663","S3675","S3692","S3705","S3716","Empty"]
[{"$nulls":3},"Azatadine dimaleate","Iopromide","Dehydrocostus Lactone","Medroxyprogesterone","Kitasamycin","Afloqualone","Umbelliferone","N-Ethylmaleimide (NEM)","Chlorobutanol","Flibanserin"]
[null,"e","Empty","S3189","S3208","S3616","S3637","S3647","S3666","S3676","S3693","S3706","S3719","Empty"]
[{"$nulls":3},"Ropinirole HCl","Fexofenadine HCl","Asiaticoside","Cefpirome sulfate","Mafenide Acetate","Ilaprazole","Carbendazim","2,6-Dihydroxypurine","Sarpogrelate hydrochloride","Topiroxostat"]
[null,"f","Empty","S3193","S3212","S3618","S3638","S3648","S3668","S3677","S3694","S3707","S3720","Empty"]
[{"$nulls":3},"Ticarcillin sodium","Moclobemide (Ro 111163)","Acetylspiramycin (ASPM)","Cefamandole nafate","Amlexanox (AA-673)","Thymopentin","Cinnamic acid","Glucosamine hydrochloride","Ethopabate","Elafibranor"]
[null,"g","Empty","S3195","S3604","S3621","S3639","S3654","S3669","S3681","S3697","S3708","S3722","Empty"]
[{"$nulls":3},"Azlocillin sodium salt","Triptolide (PG490)","Pazufloxacin mesylate","Tacrine hydrochloride hydrate","Tauroursodeoxycholic Acid (TUDCA)","Carmustine","Vitamin E Acetate","Mafenide hydrochloride","Sulfachloropyridazine","Isavuconazole"]
[null,"h","Empty","S3199","S3606","S3622","S3640","S3655","S3671","S3684","S3698","S3709","S3723","Empty"]
[{"$nulls":3},"Reboxetine mesylate","Fangchinoline","Diammonium Glycyrrhizinate","Methoxyphenamine Hydrochloride","Cefepime Dihydrochloride Monohydrate","Quinestrol","Methacholine chloride","Nortriptyline hydrochloride","Furagin","Ramosetron Hydrochloride"]
[]
[]
[]
[null,"Plate layout: L1300-13"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S3724","S3733","S3747","S3763","S3779","S3799","S3817","S3850","S3870","S3892","Empty"]
[{"$nulls":3},"Velpatasvir","Boceprevir","Levothyroxine sodium","Cinnamaldehyde","cis-Anethole","Gentisic acid","Harmine hydrochloride","Glucosamine sulfate","D-Pinitol","Isopsoralen"]
[null,"b","Empty","S3726","S3735","S3750","S3766","S3781","S3802","S3824","S3851","S3872","S3893","Empty"]
[{"$nulls":3},"Selexipag","Umeclidinium bromide","Sodium benzoate","Tanshinone IIA sulfonate sodium","Ginkgolide C","Trigonelline Hydrochloride","Quercitrin","Camphor","Guaiacol","Bornyl acetate"]
[null,"c","Empty","S3727","S3738","S3751","S3769","S3783","S3805","S3835","S3854","S3876","S3895","Empty"]
[{"$nulls":3},"Vilanterol Trifenate","Travoprost","Quinidine hemisulfate hydrate","Palmatine","Echinacoside","Stevioside","Loganin","Tetrahydropalmatine hydrochloride","Indigo","Sophoridine"]
[null,"d","Empty","S3728","S3739","S3754","S3772","S3785","S3807","S3842","S3856","S3881","S3898","Empty"]
[{"$nulls":3},"Grazoprevir","Calcipotriene","4-Hydroxybenzoic acid","5-Hydroxymethylfurfural","Notoginsenoside R1","Dehydroandrographolide","Isoquercitrin","Allantoin","Scopoletin","Hydroxy Camptothecine"]
[null,"e","Empty","S3729","S3741","Empty","S3773","S3788","S3809","S3843","S3858","S3883","S3899","Empty"]
[{"$nulls":3},"Iron sucrose","Benznidazole",null,"Tyrosol","Carvacrol","Imperatorin","Madecassoside","Lawsone","Protopine","Hederagenin"]
[null,"f","Empty","S3730","S3742","S3756","S3774","S3791","S3810","S3846","S3865","S3885","S3901","Empty"]
[{"$nulls":3},"Metaxalone","Cholic acid","Methyl salicylate","Dehydroandrographolide Succinate Potasium Salt","Succinic acid","Scutellarin","Eupatilin","Taurochenodeoxycholic acid","Pyrogallol","Astragaloside IV"]
[null,"g","Empty","S3731","S3745","S3758","S3775","S3794","S3811","S3847","S3866","S3887","S3907","Empty"]
[{"$nulls":3},"Tipiracil hydrochloride","Balsalazide disodium","Sinomenine hydrochloride","Ligustrazine hydrochloride","Palmitic acid","Ginsenoside Re","Panaxatriol","Galanthamine","α-L-Rhamnose monohydrate","Bulleyaconi cine A"]
[null,"h","Empty","S3732","S3746","S3759","S3776","S3797","S3812","S3849","S3868","S3889","S3909","Empty"]
[{"$nulls":3},"Avibactam sodium","Lumefantrine","Norcantharidin","Sophoricoside","Helicide","Monocrotaline","D-Galactose","Harmine","Arteether","Catalpol"]
[]
[]
[]
[null,"Plate layout: L1300-14"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S3914","S3930","S3959","S3974","S3985","S3997","S4007","S4019","S4031","S4043","Empty"]
[{"$nulls":3},"α-Hederin","Liquiritin","(+)-Borneol","(+)-Catechin hydrate","Methyl 4-hydroxybenzoate","Oxaceprol","Pentamidine isethionate","Avanafil","Aclidinium Bromide","Tetrahydrozoline HCl"]
[null,"b","Empty","S3919","S3935","S3965","S3975","S3986","S3998","S4009","S4020","S4034","S4044","Empty"]
[{"$nulls":3},"Hederacoside C","Nonivamide","Vanillyl Butyl Ether","Protocatechuic acid","L-Arabinose","(+)-α-Lipoic acid","Mirabegron","Sodium Picosulfate","Diphemanil Methylsulfate","Toltrazuril"]
[null,"c","Empty","S3921","S3944","S3966","S3977","S3987","S3999","S4010","S4021","S4037","S4045","Empty"]
[{"$nulls":3},"Lathyrol","Valproic acid (VPA)","Nifuratel","(-)-Borneol","L-Tryptophan","α-santonin","Acebutolol HCl","Tolcapone","Doxapram HCl","Pheniramine Maleate"]
[null,"d","Empty","S3923","S3945","S3967","S3979","S3988","S4000","S4011","S4022","S4038","S4046","Empty"]
[{"$nulls":3},"Ginsenoside Rg1","L-Cycloserine","Flavone","Zinc Undecylenate","Theophylline-7-acetic acid","Pergolide Mesylate","Ampiroxicam","Probenecid","Dibucaine HCl","Estradiol Cypionate"]
[null,"e","Empty","S3924","S3950","S3968","S3980","Empty","S4001","S4012","S4023","S4039","S4047","Empty"]
[{"$nulls":3},"Ginsenoside Rb1","Maltitol","Histamine","Pyridoxine",null,"Cabozantinib malate","Desloratadine","Procaine HCl","Methazolamide","Bisacodyl"]
[null,"f","Empty","S3925","S3951","S3969","S3982","S3992","S4002","S4014","S4024","S4040","S4048","Empty"]
[{"$nulls":3},"(-)-Epicatechin gallate","Tannic acid","Veratric acid","Batyl alcohol","D-(+)-Trehalose dihydrate","Sitagliptin phosphate monohydrate","Hyoscyamine","Homatropine Methylbromide","Norethindrone","Carbimazole"]
[null,"g","Empty","S3926","S3956","S3970","S3983","S3995","S4003","S4017","S4025","S4041","S4049","Empty"]
[{"$nulls":3},"Forsythin","Tetramethylpyrazine","Vindoline","Caryophyllene oxide","Guaiazulene","Lithocholic acid","Allylthiourea","Homatropine Bromide","Olsalazine Sodium","Valdecoxib"]
[null,"h","Empty","S3927","S3957","S3971","S3984","S3996","S4004","S4018","S4026","S4042","S4050","Empty"]
[{"$nulls":3},"Swertiamarin","Gamma-Oryzanol","Fusidine","Nordihydroguaiaretic acid (NDGA)","Thioctic acid","Ethambutol 2HCl","Sennoside B","Hydroxyzine 2HCl","Nafcillin Sodium","Valganciclovir HCl"]
[]
[]
[]
[null,"Plate layout: L1300-15"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4051","S4061","S4073","S4082","S4091","S4102","S4113","S4125","S4143","S4160","Empty"]
[{"$nulls":3},"Nabumetone","Levobupivacaine HCl","Sodium 4-Aminosalicylate","Spiramycin","Ifenprodil Tartrate","Eprosartan Mesylate","Desvenlafaxine","Sodium Phenylbutyrate","Pentoxyverine Citrate","Penicillin G Sodium"]
[null,"b","Empty","S4053","S4062","S4075","S4083","S4092","S4104","S4114","S4128","S4147","S4161","Empty"]
[{"$nulls":3},"Sertraline HCl","Ronidazole","Zinc Pyrithione","Vitamin A Acetate","Pramoxine HCl","Diminazene Aceturate","Triclabendazole","Troxipide","Azithromycin Dihydrate","Benzoic Acid"]
[null,"c","Empty","S4054","S4064","S4076","S4084","S4095","S4105","S4118","S4131","S4148","S4162","Empty"]
[{"$nulls":3},"Spironolactone","Escitalopram Oxalate","Propranolol HCl","Lomerizine 2HCl","Difluprednate","Closantel Sodium","Histamine 2HCl","Levodropropizine","Ampicillin Trihydrate","Benzethonium Chloride"]
[null,"d","Empty","S4056","S4065","S4077","S4085","S4096","S4106","S4119","S4135","S4149","S4163","Empty"]
[{"$nulls":3},"Retapamulin","Guanabenz Acetate","Mequinol","Levobetaxolol HCl","Droperidol","Closantel","Pefloxacin Mesylate Dihydrate","Clorprenaline HCl","Amfenac Sodium Monohydrate","Doxycycline Hyclate (WC2031)"]
[null,"e","Empty","S4057","S4068","S4078","S4086","S4098","S4107","S4120","S4136","S4151","S4164","Empty"]
[{"$nulls":3},"Methyclothiazide","Tinidazole","Mefenamic Acid","Loxapine Succinate","Halcinonide","Clofazimine","Sulconazole Nitrate","Carprofen","Penfluridol","Doxofylline"]
[null,"f","Empty","S4058","S4070","S4079","S4088","S4099","S4110","S4122","S4138","S4152","S4165","Empty"]
[{"$nulls":3},"Ropivacaine HCl","Guanidine HCl","Ticagrelor","Flumethasone","Dexlansoprazole","Estradiol Benzoate","Tilmicosin","Dropropizine","Ethamsylate","Benzydamine HCl"]
[null,"g","Empty","S4059","S4071","S4080","S4089","S4100","S4111","S4123","S4139","S4155","S4166","Empty"]
[{"$nulls":3},"Sodium Nitroprusside Dihydrate","Griseofulvin","Triamterene","Halobetasol Propionate","Esmolol HCl","Dicloxacillin Sodium","Timolol Maleate","Cyclizine 2HCl","Chlorzoxazone","Chlorpropamide"]
[null,"h","Empty","S4060","S4072","S4081","S4090","S4101","S4112","S4124","S4141","S4159","S4167","Empty"]
[{"$nulls":3},"Erythromycin Ethylsuccinate","Decamethonium Bromide","Sulfacetamide Sodium","Fenspiride HCl","Voglibose","Desvenlafaxine Succinate hydrate","Tolazoline HCl","Dinitolmide","Bezafibrate","Cyromazine"]
[]
[]
[]
[null,"Plate layout: L1300-16"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4169","S4178","S4188","S4200","S4210","S4223","S4235","S4246","S4257","S4267","Empty"]
[{"$nulls":3},"Teriflunomide","Climbazole","Sasapyrine","Tolperisone HCl","Benzocaine","Mevastatin","Phenazopyridine HCl","Tranylcypromine (2-PCPA) HCl","Alizapride HCl","Diacerein"]
[null,"b","Empty","S4170","S4179","S4189","S4201","S4213","S4224","S4237","S4247","S4258","S4268","Empty"]
[{"$nulls":3},"Coumarin","Mezlocillin Sodium","Cyclandelate","Florfenicol","Dirithromycin","Erythritol","Primaquine Diphosphate","Prucalopride Succinate","Luliconazole","Flufenamic acid"]
[null,"c","Empty","S4171","S4181","S4190","S4202","S4214","S4225","S4238","S4248","S4259","S4269","Empty"]
[{"$nulls":3},"Choline Chloride","Nicardipine HCl","Cinchophen","Verapamil (CP-16533-1) HCl","Sucralose","Mexiletine HCl","Cepharanthine","Bromfenac Sodium","Vilazodone HCl","Vinorelbine ditartrate (KW-2307)"]
[null,"d","Empty","S4172","S4182","S4191","S4203","S4216","S4227","S4239","S4249","S4260","S4270","Empty"]
[{"$nulls":3},"Cetylpyridinium Chloride","Nifuroxazide","Betamipron","Furaltadone HCl","Valnemulin HCl","Fidaxomicin","Bergapten","Flopropione","Tamibarotene","Oxiracetam"]
[null,"e","Empty","S4173","S4184","S4192","S4204","S4217","S4228","S4240","S4250","S4263","S4274","Empty"]
[{"$nulls":3},"1-Hexadecanol","Penciclovir","Chlorquinaldol","Isosorbide","Liothyronine Sodium","Fluorometholone Acetate","Doxylamine Succinate","Sulfamethoxypyridazine","Efaproxiral Sodium","Rotigotine"]
[null,"f","Empty","S4175","S4185","S4195","S4206","S4219","S4229","S4242","S4253","S4264","S4277","Empty"]
[{"$nulls":3},"Sulfaguanidine","Tiratricol","Broxyquinoline","Cysteamine HCl","Azaperone","Oxybuprocaine HCl","Cetrimonium Bromide (CTAB)","Epinastine HCl","Etofibrate","Bambuterol HCl"]
[null,"g","Empty","S4176","S4186","S4196","S4207","S4221","S4230","S4243","S4255","S4265","S4278","Empty"]
[{"$nulls":3},"Trometamol","Domiphen Bromide","Ethacridine lactate monohydrate","Clofibric Acid","Benzbromarone","Oxaprozin","Deoxycorticosterone acetate","Quinacrine 2HCl","Nicaraven","Carteolol HCl"]
[null,"h","Empty","S4177","S4187","S4197","S4208","S4222","S4231","S4244","S4256","S4266","S4279","Empty"]
[{"$nulls":3},"Uracil","Salicylanilide","Bemegride","Chromocarb","Piperacillin Sodium","Pilocarpine HCl","Serotonin HCl","Buspirone HCl","Brimonidine Tartrate","Demeclocycline HCl"]
[]
[]
[]
[null,"Plate layout: L1300-17"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4280","S4289","S4299","S4312","S4334","S4349","S4365","S4381","S4394","S4420","Empty"]
[{"$nulls":3},"Meclofenoxate (Centrophenoxine) HCl","Metoclopramide HCl","Dicoumarol","Carbadox","Mesoridazine Besylate","Procyclidine HCl","Phthalylsulfacetamide","Proadifen HCl","Clofoctol","Mefloquine HCl"]
[null,"b","Empty","S4281","S4291","S4301","S4316","S4335","S4351","S4366","S4382","S4396","S4502","Empty"]
[{"$nulls":3},"Tasimelteon","Labetalol HCl","(R)-(+)-Atenolol HCl","Clopamide","Metaproterenol Sulfate","Ractopamine HCl","Pinacidil","Pyrilamine Maleate","Digoxigenin","Eltrombopag"]
[null,"c","Empty","S4282","S4292","S4303","S4317","S4336","S4353","S4367","S4385","S4402","S4503","Empty"]
[{"$nulls":3},"Nelfinavir (AG 1343) Mesylate","Diphenidol HCl","9-Aminoacridine","Clorgyline HCl","Metaraminol Bitartrate","Terfenadine","Suxibuzone","Fosfomycin Tromethamine","Oxeladin Citrate","Calcium D-Panthotenate"]
[null,"d","Empty","S4283","S4293","S4304","S4322","S4338","S4354","S4368","S4387","S4404","S4504","Empty"]
[{"$nulls":3},"Cyclobenzaprine HCl","Promethazine HCl","Anisindione","Disopyramide Phosphate","Methoxamine HCl","Thiostrepton","Carbenoxolone Sodium","Bendroflumethiazide","Pasiniazid","6-Mercaptopurine (6-MP) Monohydrate"]
[null,"e","Empty","S4284","S4294","S4305","S4326","S4339","S4357","S4373","S4388","S4406","S4505","Empty"]
[{"$nulls":3},"Chloroprocaine HCl","Procainamide HCl","Anisotropine Methylbromide","Ethoxzolamide","Meticrane","Tacrine HCl","Dicyclomine HCl","Bentiromide","Pindolol","Vinblastine (NSC-49842) sulfate"]
[null,"f","Empty","S4285","S4295","S4307","S4330","S4343","S4358","S4375","S4389","S4414","S4506","Empty"]
[{"$nulls":3},"Ospemifene","Meclofenamate Sodium","Auranofin","Isoetharine Mesylate","Oxethazaine","Pimozide","Mepenzolate Bromide","Bephenium Hydroxynaphthoate","Sodium 4-aminohippurate","Acetazolamide"]
[null,"g","Empty","S4286","S4296","S4308","S4331","S4344","S4361","S4376","S4391","S4415","S4507","Empty"]
[{"$nulls":3},"Anidulafungin (LY303366)","Salmeterol Xinafoate","Benzthiazide","Meclocycline Sulfosalicylate","Oxprenolol HCl","Cinoxacin","Aceclidine HCl","Camylofin Chlorhydrate","Misoprostol","17-Hydroxyprogesterone"]
[null,"h","Empty","S4288","S4297","S4309","S4332","S4345","S4362","S4377","S4393","S4416","S4509","Empty"]
[{"$nulls":3},"Chloroambucil","Mupirocin","Bromocriptine Mesylate","Medrysone","Pentoxifylline","Glafenine HCl","Imipramine HCl","Cephapirin Sodium","Trimipramine Maleate","4-Aminoantipyrine"]
[]
[]
[]
[null,"Plate layout: L1300-18"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4510","S4521","S4532","S4543","S4556","S4566","S4581","S4591","S4601","S4618","Empty"]
[{"$nulls":3},"4-Aminobenzoic acid","DEET","Iopamidol","Trimetazidine dihydrochloride","Carzenide","DL-Panthenol","Triacetin","Nitroxoline","Clioquinol","Fenoldopam mesylate"]
[null,"b","Empty","S4512","S4522","S4534","S4544","S4558","S4568","S4583","S4593","S4602","S4619","Empty"]
[{"$nulls":3},"Aceglutamide","Dehydroacetic acid","6-Acetamidohexanoic acid","Urethane","Citiolone","Ethylvanillin","Butamben","Chlormadinone acetate","Acetohydroxamic acid","Itopride hydrochloride"]
[null,"c","Empty","S4514","S4524","S4535","S4546","S4559","S4569","S4584","S4594","S4603","S4620","Empty"]
[{"$nulls":3},"Acetylleucine","2-Ethoxybenzamide","Methylene Blue","Xylitol","Cloxiquine","Fluphenazine dihydrochloride","Butylparaben","Cephalothin sodium","Gallic acid","Cefuroxime sodium"]
[null,"d","Empty","S4515","S4525","S4536","S4547","S4561","S4570","S4585","S4595","S4604","S4622","Empty"]
[{"$nulls":3},"Ademetionine disulfate tosylate","Ethylparaben","Nitrofurantoin","8-Hydroxyquinoline","Danthron","Halothane","Succinylsulfathiazole","Cefazolin Sodium","Levofloxacin hydrate","3,4-Diaminopyridine"]
[null,"e","Empty","S4516","S4526","S4538","S4548","S4562","S4571","S4587","S4596","S4607","S4623","Empty"]
[{"$nulls":3},"(+)-Camphor","Fenbufen","Pantoprazole sodium","Aminoguanidine hydrochloride","Dehydrocholic acid","Hexylresorcinol","Pentylenetetrazol","Cefixime","2,2′-Dihydroxy-4-methoxybenzophenone","Methylbenactyzine Bromide"]
[null,"f","Empty","S4517","S4527","S4539","S4550","S4563","S4576","S4588","S4597","S4609","S4624","Empty"]
[{"$nulls":3},"Cefotaxime sodium","Fenofibric acid","Salicylic acid","Azelaic acid","Diatrizoic acid","Sulfabenzamide","Docusate Sodium","Lercanidipine hydrochloride","Diflunisal","5,5-Dimethyloxazolidine-2,4-dione"]
[null,"g","Empty","S4518","S4528","S4541","S4552","S4564","S4577","S4589","S4599","S4610","S4625","Empty"]
[{"$nulls":3},"Chloroxylenol","Furazolidone","Triclosan","Bithionol","Diethylcarbamazine citrate","Terpin hydrate","Amodiaquine dihydrochloride dihydrate","Benzyl benzoate","Mebendazole","Alcaftadine"]
[null,"h","Empty","S4520","S4530","S4542","S4553","S4565","S4578","S4590","S4600","S4612","S4626","Empty"]
[{"$nulls":3},"2-Aminoheptane","i-Inositol","Trihexyphenidyl hydrochloride","Bronopol","Diiodohydroxyquinoline","Tyloxapol","Dithranol","Benzyl alcohol","Dapson","Ethosuximide"]
[]
[]
[]
[null,"Plate layout: L1300-19"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4628","S4637","S4650","S4661","S4672","S4685","S4695","S4709","S4723","S4736","Empty"]
[{"$nulls":3},"(+/-)-Sulfinpyrazone","Prasugrel Hydrochloride","Atipamezole","Tiagabine hydrochloride","Dimenhydrinate","Efavirenz","D panthenol","Latanoprost","(-)Epicatechin","Trapidil"]
[null,"b","Empty","S4629","S4638","S4651","S4662","S4673","S4686","S4696","S4711","S4725","S4737","Empty"]
[{"$nulls":3},"Chlorotrianisene","Desogestrel","Etoricoxib","Atazanavir","Etonogestrel","Vitamin E","CarbinoxaMine Maleate","Esculetin","Benzenesulfonamide","Psoralen"]
[null,"c","Empty","S4630","S4640","S4652","S4663","S4674","S4687","S4697","S4714","S4726","S4744","Empty"]
[{"$nulls":3},"Diazoxide","Lesinurad","Sulisobenzone","Fusidate Sodium","Hydroxyprogesterone caproate","Rivastigmine","Saxagliptin hydrate","(-)-Menthol","Lauric Acid","Anethole trithione"]
[null,"d","Empty","S4631","S4641","S4655","S4664","S4676","S4689","S4698","S4716","S4727","S4748","Empty"]
[{"$nulls":3},"Prochlorperazine dimaleate salt","Tedizolid Phosphate","Sulpiride","Molsidomine","Gluconolactone","Deoxycholic acid","Vitamin K1","Evans Blue","Cinnarizine","Ondansetron Hydrochloride Dihydrate"]
[null,"e","Empty","S4633","S4646","S4656","S4665","S4678","S4690","S4699","S4717","S4731","S4749","Empty"]
[{"$nulls":3},"Isosorbide Mononitrate","Ciclesonide","Parecoxib","Rabeprazole sodium","Povidone iodine","Escin","Etretinate","Isatin","Perphenazine","Citalopram HBr"]
[null,"f","Empty","S4634","S4647","S4657","S4666","S4679","S4691","S4701","S4718","S4733","S4750","Empty"]
[{"$nulls":3},"Sodium sulfadiazine","Cefmenoxime hydrochloride","Eslicarbazepine Acetate","Sivelestat sodium tetrahydrate","Terazosin HCl","Oxybenzone","2-Deoxy-D-glucose (2-DG)","Acetylcholine iodide","Retigabine","Sulfacetamide sodium salt hydrate"]
[null,"g","Empty","S4635","S4648","S4658","S4667","S4682","S4692","S4706","S4720","S4734","S4751","Empty"]
[{"$nulls":3},"Cyproheptadine hydrochloride sesquihydrate","Dantrolene sodium hemiheptahydrate","Hydroquinidine","Lidocaine hydrochloride","Loxoprofen","Succimer","Eugenol","Cefotaxime","Retigabine 2HCl","Cisapride hydrate"]
[null,"h","Empty","S4636","S4649","S4660","S4669","S4683","S4693","S4707","S4722","S4735","S4752","Empty"]
[{"$nulls":3},"Teneligliptin hydrobromide","Atipamezole hydrochloride","Glycopyrrolate","Benzocaine hydrochloride","Sildenafil Mesylate","Guanfacine Hydrochloride","Oleic Acid","(+)-Catechin","Salvianolic acid B","Corticosterone (NSC-9705)"]
[]
[]
[]
[null,"Plate layout: L1300-20"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4753","S4788","S4816","S4834","S4844","S4852","S4866","S4876","S4889","S4935","Empty"]
[{"$nulls":3},"Ganoderic acid A","L-α-Phosphatidylcholine","Diatrizoate sodium","Propantheline bromide","Cefcapene Pivoxil Hydrochloride","Gadopentetate Dimeglumine","Nicarbazin","Robenidine Hydrochloride","Perospirone hydrochloride","Asunaprevir (BMS-650032)"]
[null,"b","Empty","S4754","S4789","S4817","S4835","S4845","S4853","S4867","S4877","S4890","S4939","Empty"]
[{"$nulls":3},"Betulin","5-Acetylsalicylic acid","Atenolol","Aceclofenac","Rabeprazole","Ecabet sodium","Propacetamol hydrochloride","Eperisone hydrochloride","Bifendate","cis-Aconitic acid"]
[null,"c","Empty","S4759","S4792","S4819","S4836","S4846","S4854","S4868","S4878","S4893","S4940","Empty"]
[{"$nulls":3},"p-Coumaric Acid","N-Acetylneuraminic acid","Saccharin","Nilutamide","Meropenem Trihydrate","Bedaquiline fumarate","Xanthinol Nicotinate","Neticonazole Hydrochloride","Cytosine","Maltol"]
[null,"d","Empty","S4768","S4797","S4820","S4837","S4847","S4856","S4869","S4880","S4894","S4941","Empty"]
[{"$nulls":3},"Melibiose","Nicergoline","Diastase","Ibudilast","Faropenem Sodium","Iproniazid","Sulfamethoxazole sodium","Cefathiamidine","D-Glucurone","Farnesol"]
[null,"e","Empty","S4769","S4803","S4830","S4838","S4848","S4859","S4870","S4881","S4896","S4949","Empty"]
[{"$nulls":3},"L-5-Hydroxytryptophan","Thymidine (NSC 21548)","Maltose","Acotiamide hydrochloride","Dalbavancin","TriacetonaMine","Cefodizime Sodium","Calcium Dobesilate","Elagolix Sodium","Nonanoic acid"]
[null,"f","Empty","S4772","S4812","S4831","S4839","S4849","S4860","S4871","S4883","S4899","S4952","Empty"]
[{"$nulls":3},"alpha-Asarone","Ceftizoxime","Piperonyl butoxide","Mosapride","Levocetirizine Dihydrochloride","Indole-3-carboxylic acid","Pyridoxal 5-phosphate monohydrate","Lynestrenol","Sulfogaiacol","Fumaric acid"]
[null,"g","Empty","S4779","S4813","S4832","S4841","S4850","S4862","S4874","S4885","S4931","S4953","Empty"]
[{"$nulls":3},"Menadiol Diacetate","Cefuroxime axetil","Tolmetin","Laurocapram","Flucloxacillin sodium","Squalene","Cefazedone","Taurolidine","Propiverine hydrochloride","Usnic acid"]
[null,"h","Empty","S4783","S4815","S4833","S4843","S4851","S4865","S4875","S4886","S4932","S4956","Empty"]
[{"$nulls":3},"Benzyl isothiocyanate","L-Cysteine HCl","Cefoxitin sodium","Potassium acetate","Tafluprost","Cefetamet pivoxil hydrochloride","Cephapirin Benzathine","Menbutone","Proxyphylline","Benzamidine HCl"]
[]
[]
[]
[null,"Plate layout: L1300-21"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4957","S4977","S4999","S5009","S5019","S5033","S5046","S5059","S5070","S5079","Empty"]
[{"$nulls":3},"Linalool","Efonidipine","Avermectin B1","Brivudine","Indobufen","Terconazole","Clonixin","Pixantrone Maleate","Mupirocin calcium","Sitagliptin"]
[null,"b","Empty","S4958","S4978","S5001","S5010","S5020","S5034","S5049","S5060","S5071","S5081","Empty"]
[{"$nulls":3},"Glycocholic acid","Azathramycin","Tofacitinib (CP-690550) Citrate","Indometacin Sodium","Tilorone dihydrochloride","Melitracen hydrochloride","Thiocolchicoside","Metadoxine","Duloxetine","Ceforanide"]
[null,"c","Empty","S4964","S4980","S5002","S5012","S5023","S5037","S5052","S5062","S5073","S5082","Empty"]
[{"$nulls":3},"Lactobionic acid","Anamorelin","Fingolimod (FTY720) HCl","Octenidine Dihydrochloride","Nadolol","Phenazine methosulfate","Granisetron","Daclatasvir Dihydrochloride","Donepezil","Vitamin K2"]
[null,"d","Empty","S4969","S4983","S5003","S5013","S5025","S5038","S5053","S5063","S5074","S5083","Empty"]
[{"$nulls":3},"Tropine","Sorbic acid","Tacrolimus (FK506)","Ioversol","Efinaconazole","Valethamate Bromide","Imazalil","Trelagliptin succinate","Argatroban Monohydrate","Lentinan"]
[null,"e","Empty","S4971","S4988","S5004","S5014","S5027","S5040","S5054","S5065","S5075","S5084","Empty"]
[{"$nulls":3},"Buparvaquone","Tiamulin fumarate","Pimecrolimus","Crisaborole (AN2728)","Mebeverine Hydrochloride","Tiamulin","Rifamycin sodium salt","Ganciclovir sodium","Acotiamide","Carbazochrome"]
[null,"f","Empty","S4973","S4991","S5005","S5015","S5029","S5041","S5055","S5066","S5076","S5085","Empty"]
[{"$nulls":3},"Iminostilbene","Valpromide","Cefotiam hydrochloride","Simeprevir (TMC435)","Etofylline","Difloxacin hydrochloride","Milbemycin Oxime","Pramipexole dihydrochloride","Xipamide","Azamethiphos"]
[null,"g","Empty","S4975","S4994","S5006","S5016","S5030","S5042","S5056","S5067","S5077","S5086","Empty"]
[{"$nulls":3},"Fimasartan","Methylcobalamin","Teprenone","Isoprinosine","Dihydralazine sulphate","Bevantolol hydrochloride","Dinoprost tromethamine","Losartan","Regorafenib (BAY-734506) Monohydrate","p-Anisaldehyde"]
[null,"h","Empty","S4976","S4996","S5007","S5017","S5032","S5043","S5058","S5069","S5078","S5091","Empty"]
[{"$nulls":3},"Sulfalene (SMPZ)","Tavaborole (AN-2690)","Delamanid","Oxyclozanide","Mephenesin","Benorylate","Revaprazan Hydrochloride","Dabrafenib Mesylate","Osimertinib mesylate","Geranyl acetate"]
[]
[]
[]
[null,"Plate layout: L1300-22"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S5092","S5109","S5132","S5159","S5200","S5212","S5228","S5243","S5256","S5281","Empty"]
[{"$nulls":3},"Febantel","Ademetionine","Casanthranol","Doxycycline","Diaveridine","Imidazolidinyl Urea","Minoxidil sulphate","Ruxolitinib Phosphate","Benproperine phosphate","Dapiprazole Hydrochloride"]
[null,"b","Empty","S5093","S5112","S5134","S5163","S5203","S5213","S5229","S5245","S5257","S5282","Empty"]
[{"$nulls":3},"Rafoxanide","alpha-Arbutin","D(-)-Arabinose","7-Methoxycoumarin","Sulbutiamine","Piroctone Olamine","Isosorbide dinitrate","Raltegravir potassium","Doxapram","Lactitol monohydrate"]
[null,"c","Empty","S5096","S5113","S5138","S5164","S5205","S5214","S5233","S5246","S5258","S5284","Empty"]
[{"$nulls":3},"SulfadiMethoxine sodium","Propyl gallate","Citral","Chlorotetracycline","Nilotinib hydrochloride","Imidocarb dipropionate","Fenretinide (NSC 374551)","Entecavir","Revefenacin","Adenosine 5'-monophosphate monohydrate"]
[null,"d","Empty","S5100","S5114","S5141","S5167","S5206","S5215","S5234","S5247","S5261","S5286","Empty"]
[{"$nulls":3},"Pralidoxime Iodide","Hydroquinine","Pyrithioxin","Benzyl cinnamate","Benzylpenicillin potassium","Abacavir (1592U89)","Nintedanib Ethanesulfonate Salt","Selamectin","Ufenamate","Ramatroban"]
[null,"e","Empty","S5102","S5117","S5143","S5174","S5208","S5217","S5238","S5250","S5266","S5288","Empty"]
[{"$nulls":3},"stachyose tetrahydrate","Doramectin","Citropten","Kojic acid","Ciprofloxacin hydrochloride hydrate","Arformoterol Tartrate","Solifenacin (YM905)","Darunavir","Stiripentol","Estropipate"]
[null,"f","Empty","S5105","S5121","S5145","S5176","S5209","S5222","S5239","S5253","S5273","S5289","Empty"]
[{"$nulls":3},"Proanthocyanidins","Phytol","Protoporphyrin IX","Fructose","Enoxacin Sesquihydrate","Coluracetam","Paroxetine mesylate","Cisapride (R 51619)","Canrenone","Ceftezole"]
[null,"g","Empty","S5106","S5126","S5155","S5177","S5210","S5224","S5240","S5254","S5278","S5291","Empty"]
[{"$nulls":3},"Lanolin","Aleuritic Acid","Raffinose","Naproxen","Sulfamethazine Sodium Salt","Adrafinil","Lenvatinib (E7080) Mesylate","Dasatinib hydrochloride","Tedizolid (TR-700)","sulfaisodimidine"]
[null,"h","Empty","S5108","S5130","S5157","S5179","S5211","S5227","S5241","S5255","S5279","S5292","Empty"]
[{"$nulls":3},"Tylosin","Taurocholic acid sodium salt hydrate","Thymol","Ropivacaine Mesilate","4-Aminosalicylic acid","Erythromycin thiocyanate","Lapatinib ditosylate monohydrate","Nicardipine","Fendiline hydrochloride","Diazolidinyl urea"]
[]
[]
[]
[null,"Plate layout: L1300-23"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S5293","S5305","S5328","S5351","S5361","S5372","S5394","S5404","S5416","S5440","Empty"]
[{"$nulls":3},"Nimustine Hydrochloride","Bromisoval","Gamithromycin","Cefmetazole sodium","Bendazac","Methyl Aminolevulinate Hydrochloride","Tizoxanide","Paritaprevir (ABT-450)","Metyrapone","Berberine Sulfate"]
[null,"b","Empty","S5294","S5309","S5331","S5352","S5363","S5377","S5395","S5405","S5418","S5447","Empty"]
[{"$nulls":3},"Cephalotin acid","Propyphenazone (4-Isopropylantipyrine)","Ceftezole sodium","Cefminox Sodium","Pikamilone","Dibutyl phthalate","Phenolphthalein","Propylparaben","Parecoxib Sodium","Triprolidine Hydrochloride"]
[null,"c","Empty","S5295","S5311","S5333","S5353","S5365","S5378","S5397","S5406","S5419","S5450","Empty"]
[{"$nulls":3},"Lincomycin Hydrochloride Monohydrate","Pyridoxal phosphate","Sulbenicillin Sodium","Cefpiramide sodium","Alogliptin","Dimethyl phthalate","Chlorhexidine","Sultamicillin Tosylate","1,4-Cineole","Sofalcone"]
[null,"d","Empty","S5297","S5320","S5339","S5356","S5366","S5385","S5398","S5407","S5420","Empty","Empty"]
[{"$nulls":3},"Vidarabine monohydrate","Octinoxate","4-Allylanisole","Ceftiofur","Fipronil","Imidafenacin","Nefazodone hydrochloride","Squalane","Clindamycin alcoholate"]
[null,"e","Empty","S5298","S5322","S5341","S5357","S5367","S5388","S5399","S5410","S5424","S5453","Empty"]
[{"$nulls":3},"Amoxicillin trihydrate","Sodium gualenate","Metroprolol succinate","Safinamide","Ethyl Oleate","Betrixaban","Chlorprothixene hydrochloride","Chloramphenicol sodium succinate","Carbaryl","Hyperoside"]
[null,"f","Empty","S5299","S5325","S5343","S5358","S5368","S5389","S5401","S5411","S5428","Empty","Empty"]
[{"$nulls":3},"Tosufloxacin p-Toluenesulfonate Hydrate","Nitisinone","Vanillic acid","Regadenoson","Lactitol","Betrixaban maleate","Tegaserod Maleate","Sultamicillin","Promazine hydrochloride"]
[null,"g","Empty","S5301","S5326","S5345","S5359","S5369","S5392","S5402","S5413","S5430","S5457","Empty"]
[{"$nulls":3},"Carglumic Acid","Dolasetron","(+/-)-nerolidol","Butoconazole","Ethoxyquin","Mepivacaine","Dasabuvir (ABT-333)","Ertugliflozin","Metoprolol","Curculigoside"]
[null,"h","Empty","S5302","S5327","S5350","S5360","S5371","S5393","S5403","S5414","S5435","S5458","Empty"]
[{"$nulls":3},"6-Methoxy-2-naphthoic acid","Meisoindigo","Cefpodoxime proxetil","Diflorasone","Ajmaline","Cyclofenil","Ombitasvir (ABT-267)","Diflucortolone valerate","Quinacrine Dihydrochloride Dihydrate","Verbascoside"]
[]
[]
[]
[null,"Plate layout: L1300-24"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S5459","S5480","S5488","S5500","S5527","S5539","S5552","S5561","S5573","S5596","Empty"]
[{"$nulls":3},"Aucubin","Clidinium Bromide","Fluorescein","Amodiaquine hydrochloride","Salmeterol","Olprinone","Amenamevir","Ethacrynic Acid","Tilmicosin phosphate","(1S)-(-)-α-Pinene"]
[null,"b","Empty","S5460","S5481","S5490","S5501","S5528","S5540","S5553","S5562","S5580","S5597","Empty"]
[{"$nulls":3},"Vitexin-2-O-rhaMnoside","Molindone hydrochloride","Disopyramide","Hydrocortisone acetate","Acetophenone","Landiolol hydrochloride","Kasugamycin hydrochloride","2-Hydroxybenzyl alcohol","Arabic gum","(1R)-(-)-Menthyl acetate"]
[null,"c","Empty","S5466","S5482","S5491","S5502","S5530","S5541","S5554","S5563","S5581","S5599","Empty"]
[{"$nulls":3},"Saikosaponin A","Prilocaine hydrochloride","Lomefloxacin","Ilaprazole sodium","Geraniol","Dimetridazole","Lanatoside C","Thioridazine hydrochloride","Olmesartan","Sodium cholate"]
[null,"d","Empty","S5473","S5483","S5492","S5503","S5531","S5543","S5555","S5564","S5582","S5604","Empty"]
[{"$nulls":3},"Pivmecillinam hydrochloride","Tribenzagan Hydrochloride","Econazole","O-Acetyl-L-carnitine hydrochloride","Doripenem","1, 10-Phenanthroline monohydrate","Pamabrom","Xylazine","Cytarabine hydrochloride","Diphenylamine Hydrochloride"]
[null,"e","Empty","S5476","S5484","S5493","S5504","S5532","S5544","S5556","S5565","S5583","S5614","Empty"]
[{"$nulls":3},"Rolapitant","Rimantadine Hydrochloride","Atropine sulfate","Ropivacaine","Erythromycin estolate","D-Ribose","(-)-Sparteine Sulfate","Triflupromazine hydrochloride","Cinnamyl acetate","(+)-Longifolene"]
[null,"f","Empty","S5477","S5485","S5494","S5505","S5535","S5546","S5558","S5566","S5585","S5618","Empty"]
[{"$nulls":3},"Gefarnate","Desipramine Hydrochloride","Salbutamol","2’-deoxyuridine","Moxifloxacin","Sulfacetamide","D-Pantothenate Sodium","Dapagliflozin propanediol monohydrate","Citronellal","Hippuric acid"]
[null,"g","Empty","S5478","S5486","S5497","S5507","S5537","S5547","S5559","S5567","S5592","S5619","Empty"]
[{"$nulls":3},"Dantrolene sodium","Fluorometholone","Iopanoic acid","Trimebutine maleate","Tizanidine","Hydroxylammonium chloride","(+/-)-tetrahydropalmatine","Trimethadione","Vitamin A","Betahistine"]
[null,"h","Empty","S5479","S5487","S5498","S5515","S5538","S5550","S5560","S5568","S5594","S5621","Empty"]
[{"$nulls":3},"Cloperastine hydrochloride","Cefoperazone sodium","Betahistine mesylate","Penicillin G Procaine","Tropisetron","Ethyl gallate","Midecamycin","Tocofersolan","(-)-(S)-α-terpineol","Cilastatin"]
[]
[]
[]
[null,"Plate layout: L1300-25"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S5623","S5648","S5657","S5666","S5683","S5702","S5716","S5726","S5735","S5747","Empty"]
[{"$nulls":3},"Bedaquiline","Iguratimod","Ertapenem sodium","Moxisylyte hydrochloride","Isoproterenol sulfate dihydrate","Fenipentol","Abemaciclib (LY2835219)","Triiodothyronine","Midodrine","Morantel tartrate"]
[null,"b","Empty","S5625","S5649","S5658","S5667","S5685","S5703","S5717","S5727","S5736","S5749","Empty"]
[{"$nulls":3},"Ammonium lactate","Hydroxyzine pamoate","Omeprazole Sodium","Fruquintinib (HMPL-013)","Desoximetasone","Carvedilol Phosphate","Acetohexamide","Tetryzoline","Benzathine penicilline","Chlorpromazine"]
[null,"c","Empty","S5626","S5651","S5659","S5669","S5692","S5705","S5718","S5728","S5737","S5750","Empty"]
[{"$nulls":3},"Benzalkonium chloride","Dexrazoxane","Emedastine","Isoxsuprine hydrochloride","Mexenone","Raceanisodamine","Acrivastine","Delapril Hydrochloride","Diclofenac Epolamine","DL-Norepinephrine hydrochloride"]
[null,"d","Empty","S5627","S5652","S5661","S5670","S5693","S5709","S5719","S5729","S5739","S5752","Empty"]
[{"$nulls":3},"Amsacrine hydrochloride","Elbasvir","Tiaprofenic acid","Chloropyramine hydrochloride","Levomilnacipran Hydrochloride","Norgestrel","Ceftizoxime sodium","Fosfosal","Nebivolol","Abametapir"]
[null,"e","Empty","S5637","S5653","S5662","S5673","S5697","S5710","S5720","S5730","S5740","S5754","Empty"]
[{"$nulls":3},"Cefotiam Hexetil Hydrochloride","Indigo carmine","Ranitidine","Mivacurium chloride","Isopropamide Iodide","Ambroxol","Glecaprevir","Alimemazine Tartrate","Palonosetron","Baricitinib phosphate"]
[null,"f","Empty","S5638","S5654","S5663","S5679","S5698","S5713","S5722","S5732","S5741","S5756","Empty"]
[{"$nulls":3},"Cefozopran hydrochloride","Indacaterol","Minaprine dihydrochloride","Dolasetron Mesylate","Ketorolac tromethamine salt","Pravastatin","Oxantel Pamoate","Sebacic acid","Quetiapine","Methyl Stearate"]
[null,"g","Empty","S5641","S5655","S5664","S5680","S5700","S5714","S5724","S5733","S5742","S5757","Empty"]
[{"$nulls":3},"Rhodamine B","Venlafaxine","Orphenadrine Hydrochloride","(-)-Verbenone","Phthalylsulfathiazole","lurasidone","Dichlorophen","Stearic acid","Deferoxamine mesylate (Ba 33112)","Isoeugenol"]
[null,"h","Empty","S5647","S5656","S5665","S5682","S5701","S5715","Empty","S5734","S5743","S5759","Empty"]
[{"$nulls":3},"Emedastine Difumarate","Diphenylpyraline hydrochloride","Drofenine Hydrochloride","Methyl linolenate","Alvimopan dihydrate (LY246736 dihydrate)","Atorvastatin",null,"Midodrine hydrochloride","γ-Linolenic acid","Methyl linoleate"]
[]
[]
[]
[null,"Plate layout: L1300-26"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S5761","S5776","S5787","S5823","S5857","S5871","S5909","S5935","S5950","S6014","Empty"]
[{"$nulls":3},"Citric acid","Proflavine","Dronedarone","L-Pyroglutamic acid","Trazodone","Trans-Tranilast","Anagliptin","Alvimopan","Fingolimod","Isonicotinic acid"]
[null,"b","Empty","S5762","S5778","S5795","S5827","S5858","S5872","S5911","S5936","S5951","S6015","Empty"]
[{"$nulls":3},"Methyl Oleate","Esmolol","Rasagiline","Citronellyl acetate","Vilazodone","Estradiol dipropionate","Bictegravir","Cefazolin","Cefoxitin","Benzylcetyldimethylammonium chloride hydrate"]
[null,"c","Empty","S5763","S5779","S5802","S5830","S5859","S5873","S5921","S5938","S5952","S6035","Empty"]
[{"$nulls":3},"D-Mannose","Trimetazidine","Alprenolol hydrochloride","L-Xylose","Sancycline","Scopolamine HBr trihydrate","Cyclopentolate Hydrochloride","Benazepril","Baloxavir marboxil","2-Naphthol"]
[null,"d","Empty","S5765","S5780","S5805","S5842","S5861","S5874","S5923","S5939","S6003","S6041","Empty"]
[{"$nulls":3},"Sodium Dehydrocholate","Prazosin","Allopregnanolone","Cabergoline","Lercanidipine","D-Carnitine hydrochloride","Celiprolol hydrochloride","Bendamustine (SDX105)","Ataluren (PTC124)","Dibutyl sebacate"]
[null,"e","Empty","S5766","S5781","S5808","S5843","S5862","S5886","S5924","S5940","S6006","S6047","Empty"]
[{"$nulls":3},"Alfuzosin","Raloxifene","Relugolix","Cinitapride Hydrogen Tartrate","Metoclopramide","Hodostin","Olanexidine Hydrochloride semihydrate","Bepotastine","Imidazole","Lactose"]
[null,"f","Empty","S5767","S5782","S5812","S5847","S5863","S5887","S5925","S5943","S6007","S6049","Empty"]
[{"$nulls":3},"Aliskiren","Doxazosin","Choline Fenofibrate","Ethacrynate Sodium","Metronidazole Benzoate","Khellin","Olodaterol hydrochloride","Bromhexine","Bisphenol A","(+)-(S)-Carvone"]
[null,"g","Empty","S5768","S5783","S5816","S5848","S5868","S5900","S5926","S5944","S6010","S6052","Empty"]
[{"$nulls":3},"Fenoterol hydrobromide","Montelukast","Pyrvinium","Frovatriptan Succinate","DL-Menthol","Edrophonium chloride","Pitolisant hydrochloride","Butenafine","Sodium L-lactate","Saccharin sodium salt hydrate"]
[null,"h","Empty","S5769","S5784","S5821","S5854","S5869","S5901","S5927","S5948","S6011","S6053","Empty"]
[{"$nulls":3},"Fenoterol","Vancomycin","Linoleic acid","Xylometazoline","Cortisone","Canagliflozin hemihydrate","Proguanil","Amodiaquine","Acetamide","Phenylglyoxylic acid"]
[]
[]
[]
[null,"Plate layout: L1300-27"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S6055","S6115","S6189","S6221","S6251","S6284","S6346","S6409","S6440","S6452","Empty"]
[{"$nulls":3},"(S)-(−)-Limonene","Pyridoxal 5′-phosphate hydrate","Acid Yellow 36","Methyl cinnamate","Terephthalic acid","Tetraethylammonium bromide","L-(+)-Arabinose","Zucapsaicin","Halazone","Delavirdine mesylate"]
[null,"b","Empty","S6058","S6118","S6197","S6223","S6257","S6288","S6400","S6410","S6441","S6453","Empty"]
[{"$nulls":3},"β-Caryophyllene","Terpinen-4-ol","Dimethylamine hydrochloride","Triethyl citrate","N-Acetylglucosamine","Chlorhexidine diacetate","Glucosamine","Clemizole","Riboflavin Tetrabutyrate","Bicyclol"]
[null,"c","Empty","S6065","S6121","S6202","S6231","S6258","S6296","S6402","S6411","S6442","S6454","Empty"]
[{"$nulls":3},"Congo Red","Maltotriose","Butylated hydroxytoluene","Methyl nicotinate","1,2-Propanediol","Octanoic acid","2-Aminoethanethiol","Nimorazole","Chlorphenesin","Docosahexaenoic Acid"]
[null,"d","Empty","S6067","S6136","S6207","S6232","S6262","S6316","S6403","S6421","S6443","S6455","Empty"]
[{"$nulls":3},"2,4-dichlorobenzyl alcohol","(±)-α-Bisabolol","Levulinic acid","Methylamine hydrochloride","Ammonium formate","N-Acetyl-L-tyrosine","Chloramine-T","Diroximel Fumarate","Chromium picolinate","Clebopride malate"]
[null,"e","Empty","S6068","S6152","S6210","S6233","S6264","S6324","S6404","S6432","S6444","S6456","Empty"]
[{"$nulls":3},"Doxycycline monohydrate","Acid Red 27","Ethanolamine hydrochloride","Tartaric acid","Rutin hydrate","5-Methoxytryptamine","Salicylamide","Cevimeline HCl hemihydrate","Triclocarban","Glycyrrhetinic acid"]
[null,"f","Empty","S6073","S6172","S6215","S6234","S6272","S6335","S6405","S6433","S6447","S6457","Empty"]
[{"$nulls":3},"Diclofenac acid","Brucine sulfate heptahydrate","Phthalic acid","Pentadecanoic acid","Glycolic acid","Ethyl maltol","Octisalate","Udenafil","Carazolol","Flurbiprofen Axetil"]
[null,"g","Empty","S6079","S6173","S6217","S6235","S6275","S6342","S6407","S6435","S6448","S6459","Empty"]
[{"$nulls":3},"2-Methylhexanoic acid","Amylmetacresol","o-Toluic acid","Sodium dehydroacetate","(−)-β-Pinene","Glycerol Tri-n-octanoate","Tulobuterol hydrochloride","Mequitazine","Ibuprofen piconol","Nifurtimox"]
[null,"h","Empty","S6104","S6188","S6218","S6250","S6281","S6343","S6408","S6439","S6450","S6461","Empty"]
[{"$nulls":3},"(±)-α-Tocopherol","p-Toluenesulfonic acid monohydrate","Sodium lauryl sulfate","L-Lactic acid","Sodium Thiocyanate","D-Glucuronic acid","Hexetidine","Talniflumate","Apronal","Permethrin"]
[]
[]
[]
[null,"Plate layout: L1300-28"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S6462","S6476","S6588","S7028","S7158","S7303","S7513","S7633","S7678","S7786","Empty"]
[{"$nulls":3},"Amezinium (methylsulfate)","Eicosapentaenoic Acid","Methylprednisolone hemisuccinate","Duvelisib (IPI-145)","Abemaciclib mesylate (LY2835219)","Rilpivirine","Trelagliptin","Lomitapide Mesylate","Sacubitril/valsartan (LCZ696)","Erlotinib (OSI-774)"]
[null,"b","Empty","S6465","S6478","S6590","S7059","S7160","S7397","S7536","S7635","S7721","S7787","Empty"]
[{"$nulls":3},"Tafamidis","Fipexide hydrochloride","Hydrocortisone butyrate","Tezacaftor (VX-661)","Glasdegib (PF-04449913)","Sorafenib (BAY 43-9006)","Lorlatinib (PF-6463922)","Lomitapide","Monomethyl auristatin E (MMAE)","Docetaxel Trihydrate"]
[null,"c","Empty","S6467","S6484","S6601","S7067","S7179","S7411","S7550","S7650","S7754","S7810","Empty"]
[{"$nulls":3},"Fosfluconazole","uridine triacetate","(±)-Equol","Tepotinib (EMD 1214063)","Siponimod (BAF312)","Ascomycin (FK520)","Erythromycin Cyclocarbonate","Peficitinib (ASP015K)","Gilteritinib (ASP2215)","Afatinib (BIBW2992) Dimaleate"]
[null,"d","Empty","S6468","S6487","S6611","S7077","S7194","S7417","S7559","S7660","S7766","S7818","Empty"]
[{"$nulls":3},"Trandolapril","fluticasone furoate","Cyclothiazide","Cilengitide trifluoroacetate","Olverembatinib dimesylate (HQP1351)","Puromycin (CL13900) 2HCl","Darolutamide (ODM-201)","Obeticholic Acid","Cabotegravir (GSK1265744)","Pexidartinib (PLX3397)"]
[null,"e","Empty","S6469","S6492","S6614","S7083","S7252","S7440","S7579","S7663","S7781","S7834","Empty"]
[{"$nulls":3},"Thonzylamine","Doravirine (MK-1439)","Fursultiamine","Ceritinib (LDK378)","Selinexor (KPT-330)","Ribociclib (LEE011)","Ledipasvir (GS5885)","Ruboxistaurin (LY333531) HCl","Sunitinib (SU11248)","Cyclo (-RGDfK)"]
[null,"f","Empty","S6470","S6508","S7000","S7091","S7280","Empty","S7594","S7668","S7782","S7844","Empty"]
[{"$nulls":3},"Fluralaner","Mitapivat","AP26113-analog (ALK-IN-1)","Zotarolimus (ABT-578)","Edoxaban tosylate Monohydrate",null,"Abscisic Acid (Dormin)","Picropodophyllin (PPP)","Dasatinib Monohydrate","Cyclo(RGDyK)"]
[null,"g","Empty","S6472","S6585","S7007","S7121","Empty","S7470","S7605","S7672","S7783","S7852","Empty"]
[{"$nulls":3},"Tinoridine hydrochloride","Triethylenetetramine Dihydrochloride","Binimetinib (MEK162)","Tovorafenib (MLN2480)",null,"Triapine","Filgotinib (GLPG0634)","Omaveloxolone (RTA-408)","Combretastatin A4","Eliglustat"]
[null,"h","Empty","S6473","S6587","S7025","S7156","S7297","S7505","S7625","S7674","S7784","S7856","Empty"]
[{"$nulls":3},"Pinaverium bromide","Clobetasone butyrate","Embelin","Marimastat (BB-2516)","Osimertinib (AZD9291)","(S)-crizotinib","Niraparib (MK-4827) tosylate","Savolitinib (AZD6094)","Fumagillin","Tenofovir Alafenamide (GS-7340)"]
[]
[]
[]
[null,"Plate layout: L1300-29"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S7858","S7975","S8041","S8116","S8183","S8401","S8567","S8757","S9003","S9141","Empty"]
[{"$nulls":3},"Dibutyryl-cAMP (Bucladesine)","Favipiravir (T-705)","Cobimetinib (GDC-0973)","Acalabrutinib (ACP-196)","Pimavanserin tartrate","Erdafitinib (JNJ-42756493)","Tucidinostat (Chidamide)","Ripretinib (DCC-2618)","(R)-(-)-Mandelic acid","Berbamine"]
[null,"b","Empty","S7867","S7995","S8048","S8133","S8194","S8432","S8583","S8765","S9007","S9142","Empty"]
[{"$nulls":3},"Oleuropein","Ripasudil (K-115) hydrochloride dihydrate","Venetoclax (ABT-199)","Resiquimod (R-848)","umbralisib (TGR-1202)","Troglitazone (CS-045)","Repotrectinib (TPX-0005)","Abrocitinib (PF-04965842)","2'-deoxyguanosine","Sparteine"]
[null,"c","Empty","S7935","S7998","S8051","S8134","S8195","S8538","S8592","S8791","S9032","S9143","Empty"]
[{"$nulls":3},"Y-39983 HCl","Entrectinib (RXDX-101)","Macitentan (ACT 064992)","Radotinib","Oclacitinib maleate","Ritlecitinib (PF-06651600)","Pamiparib (BGB-290)","Zanubrutinib (BGB-3111)","Sanguinarine","Ammonium Glycyrrhizate"]
[null,"d","Empty","S7936","S8016","S8057","S8135","S8205","S8539","S8594","S8817","S9042","S9179","Empty"]
[{"$nulls":3},"Belumosudil (KD025)","Vonoprazan Fumarate (TAK-438)","Pacritinib (SB1518)","Riociguat (BAY 63-2521)","Enasidenib (AG-221)","TAS-102","Tirofiban Hydrochloride","Almonertinib (HS-10296)","Wedelolactone","Catharanthine hemitartrate"]
[null,"e","Empty","S7952","S8018","S8067","S8136","S8206","S8540","S8615","S8871","S9046","S9193","Empty"]
[{"$nulls":3},"Ozanimod (RPC1063)","Nirogacestat (PF-03084014)","Vorapaxar (MK-5348)","Sivelestat (ONO-5046)","Ivosidenib (AG-120)","Voxelotor (GBT440)","Sodium dichloroacetate (DCA)","Omadacycline tosylate","Berberine","Aristolochic acid A"]
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[{"$nulls":3},"ETC-1002","Capivasertib (AZD5363)","Bardoxolone Methyl","Halofuginone","Ponesimod","Asciminib (ABL001)","Ipragliflozin (ASP1941)","Letermovir (AIC246)","Harringtonine","Melamine"]
[null,"g","Empty","Empty","S8022","S8101","S8166","S8294","S8558","S8726","S9001","S9101","S9222","Empty"]
[{"$nulls":4},"Empagliflozin (BI 10773)","CB-5083","tirabrutinib(ONO-4059) hydrochloride","Olmutinib (BI 1482694)","Tofogliflozin(CSG 452)","Anlotinib (AL3818) dihydrochloride","Malic acid","Ingenol","Dipotassium glycyrrhizinate"]
[null,"h","Empty","S7960","S8034","S8103","S8171","S8362","S8565","S8752","S9002","S9140","S9227","Empty"]
[{"$nulls":3},"Larotrectinib (LOXO-101) sulfate","Apremilast (CC-10004)","Sotagliflozin (LX4211)","Daprodustat (GSK1278863)","Tucatinib","Omarigliptin (MK-3102)","leniolisib (CDZ 173)","L-Fucose","Pulegone","Sinensetin"]
[]
[]
[]
[null,"Plate layout: L1300-30"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S9240","S9329","S9380","S9457","S9469","S9510","S5856","S6624","S8861","S9102","Empty"]
[{"$nulls":3},"Isofraxidin","Orcinol","5,7-Dihydroxy-4-methylcoumarin","Phensuximide","Haloperidol Decanoate","Protriptyline hydrochloride","Trifluoperazine","Avatrombopag","Mavacamten (MYK-461)","Magnolin"]
[null,"b","Empty","S9249","S9338","S9382","Empty","S9470","S9552","S5934","S6626","S9015","S9110","Empty"]
[{"$nulls":3},"Securinine","Octyl gallate","Thymine",null,"Penbutolol Sulfate","Farrerol","(-)-Fenchone","Brequinar (DUP785)","Homoharringtonine (CGX-635)","Morin"]
[null,"c","Empty","S9252","S9346","S9383","S9459","S9472","S9560","S6490","S6631","S9019","S9111","Empty"]
[{"$nulls":3},"Corydaline","1-Indanone","Methyl palmitate","Mecamylamine Hydrochloride","Oxtriphylline","Anisodamine Hydrobromide","Vadadustat","Belotecan (CKD-602) hydrochloride","Quillaic acid","Isorhamnetin"]
[null,"d","Empty","S9263","S9349","S9400","S9460","S9500","S9566","S6581","S6729","S9024","S9123","Empty"]
[{"$nulls":3},"3-n-Butylphathlide","D-(+)-Raffinose pentahydrate","Rhynchophylline","Ethotoin","Valbenazine tosylate","Bepridil hydrochloride","Fosamprenavir calcium salt","Besifovir","3-O-Acetyl-11-keto-β-boswellic acid (AKBA)","Eriodictyol"]
[null,"e","Empty","S9311","S9351","S9413","S9461","S9502","S9567","S6582","S6742","S9028","S9171","Empty"]
[{"$nulls":3},"Germacrone","2'-Deoxyadenosine monohydrate","Yangonin","Benzonatate","Madecassic acid","Indinavir Sulfate","Ozenoxacin","Etofenamate","Cimifugin","Harpagoside"]
[null,"f","Empty","S9321","S9354","S9451","S9463","S9507","S9568","S6583","S7716","S9050","S9183","Empty"]
[{"$nulls":3},"Topotecan","Oxalic acid","Uridine 5'-monophosphate","Demecarium Bromide","(−)-Norepinephrine","Sapropterin Dihydrochloride","Apraclonidine HCl","Pimitespib (TAS-116)","Boldine","Ruscogenin"]
[null,"g","Empty","S9326","S9368","S9452","S9466","S9508","S2934","S6589","S8781","S9053","S9192","Empty"]
[{"$nulls":3},"Scopolamine","ADP","10-Undecenoic acid","Methenamine Hippurate","Brimonidine","Ensartinib (X-396) dihydrochloride","Norethisterone Enanthate","Selpercatinib (LOXO-292)","Irisflorentin","Vitexin"]
[null,"h","Empty","S9327","S9373","S9454","S9467","S9509","S4421","S6593","S8848","S9086","S9200","Empty"]
[{"$nulls":3},"Carboprost","Neryl acetate","Undecanoic acid","Thiothixene","Tiapride Hydrochloride","Josamycin","Methylprednisolone sodium succinate","Futibatinib (TAS-120)","Dihydrocapsaicin","Pneumocandin B0"]
[]
[]
[]
[null,"Plate layout: L1300-31"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S9224","S9519","S6657","S0487","S0074","S3273","S9641","S1421","S3101","S3314","Empty"]
[{"$nulls":3},"Dehydroandrographolide Succinate","Fadrozole (CGS16949A)","2-Aminoethyl Diphenylborinate (2-APB)","Sulfatinib","Relebactam","Hypericin","Pibrentasvir (ABT-530)","Staurosporine (AM-2282)","2-Deoxy-D-ribose","2-Methylpentanoic acid"]
[null,"b","Empty","S9248","S9520","S6659","S2288","S0088","S3301","S0165","S1981","S3111","S3332","Empty"]
[{"$nulls":3},"Homoorientin","Lasofoxifene Tartrate","Rimegepant (BMS-927711)","Rubitecan","Pemigatinib (INCB054828)","Cynarin","Ampalex (CX-516)","Adenine","Pyridoxal hydrochloride","D-Mannosamine hydrochloride"]
[null,"c","Empty","S9270","S2100","S6663","S2447","S0325","S6664","S0323","S2997","S3134","S3341","Empty"]
[{"$nulls":3},"Dracohodin perochlorate","Temocapril","Resmetirom (MGL-3196)","Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222)","Treprostinil sodium","Gefapixant","Antineoplaston A10","DL-Tartaric acid","D-(-)-Tartaric acid","Palmitoleic acid"]
[null,"d","Empty","S9281","S2307","S6665","S6813","S0398","S6852","S0474","S3009","S3141","S3360","Empty"]
[{"$nulls":3},"Peimine","Roquinimex","Sparsentan (PS-433540, RE-021)","Mobocertinib (TAK788)","Astemizole","Gossypol","Avacopan (CCX168)","Menthone","Maleimide","Bis(2-ethylhexyl) phthalate"]
[null,"e","Empty","S9285","S2426","S6676","S6829","S0994","S6889","S0721","S3029","S3143","S3371","Empty"]
[{"$nulls":3},"Fargesin","Tirapazamine","Ebselen","Dithiothreitol (DTT)","Ipragliflozin L-Proline","Monomethyl Fumarate","Ticlopidine","Malonic acid","Pyruvic acid","N-Acetyl-D-mannosamine"]
[null,"f","Empty","S9288","S2428","S8949","S6830","S2440","S6896","S0869","S3069","S3152","S3743","Empty"]
[{"$nulls":3},"Casticin","Isopropyl myristate","Olutasidenib (FT-2102)","o-Phenanthroline","Vindesine sulfate","Clascoterone","Carbetapentane","Deoxycholic acid sodium salt","Glutaric acid","Oxiglutatione"]
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[{"$nulls":3},"Gelsemine","Fabomotizole hydrochloride","Myristic Acid","3'-Fluoro-3'-deoxythymidine (Alovudine)","Brilliant Blue G","Capric acid","Barnidipine","Maleic acid","Amiloxate","Ceftaroline Fosamil"]
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[{"$nulls":3},"Triptonide","Fexinidazole","Pleconaril","Molnupiravir (EIDD-2801)","Trigonelline","Orelabrutinib (ICP-022)","Irinotecan (CPT-11)","Pyrazole","Myosmine","Apatinib"]
[]
[]
[]
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[{"$nulls":3},"Indole","Perhexiline maleate","Crotamiton","Rhodamine 123","D-Gluconic acid","Emamectin Benzoate","Eliglustat hemitartrate","Neotame","Tetraethylammonium chloride","Quinidine hydrochloride monohydrate"]
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[{"$nulls":3},"3-Hydroxybenzoic acid","Ginsenoside Ro","Indocyanine green","Mebrofenin","3-Phenoxybenzoic acid","Rifamycin S","Ledipasvir acetone","Dimercaprol","Tetracycline","Atropine"]
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[{"$nulls":3},"DOTAP chloride","Enarodustat (JTZ-951)","Tecovirimat","Bendazol","Resazurin sodium","Tenofovir alafenamide hemifumarate","Pleuromutilin","Guanabenz","Sodium nitroprusside","Balsalazide"]
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[{"$nulls":3},"β-Elemene","Fluzoparib (SHR-3162)","Monocaprylin","Rhodamine 6G","Phenol Red sodium salt","Ertugliflozin L-pyroglutamic acid","2-Phenylacetamide","Thiamine monochloride","Iohexol","Fostamatinib disodium hexahydrate"]
[]
[]
[]
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[{"$nulls":3},"Regorafenib Hydrochloride","Levobupivacaine","Cinacalcet","Cefodizime","Megestrol","Beclamide","Menadione bisulfite sodium","Urapidil","Oxolamine Citrate","Puromycin aminonucleoside"]
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[{"$nulls":3},"Ceritinib dihydrochloride","Perospirone","L-Thyroxine sodium salt pentahydrate","Spectinomycin dihydrochloride pentahydrate","Ipratropium bromide monohydrate","L-Carnitine hydrochloride","Thiamine nitrate","Dicloxacillin Sodium hydrate","Eicosapentaenoic acid ethyl ester","Lanraplenib (GS-9876)"]
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[{"$nulls":3},"Oxacillin sodium","Cefpiramide","Furosemide sodium","Prednisone acetate","Norethindrone acetate","DL-Carnitine","Vardenafil hydrochloride","Pemetrexed","Amdinocillin","6-Aminonicotinamide"]
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[{"$nulls":3},"Procaine penicillin G","Ribociclib hydrochloride","Rucaparib Camsylate","Ceftiofur sodium","Bromfenac sodium hydrate","Bisoprolol","Metformin","Hydrocortisone hemisuccinate","Lusutrombopag","Iodoacetamide"]
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[{"$nulls":3},"Ciprofloxacin hydrochloride","Ribociclib succinate","Promethazine","Pantoprazole sodium hydrate","Propafenone","Alverine","Tenofovir Disoproxil","Methylprednisolone Acetate","Chloroquine (NSC-187208)","Remogliflozin etabonate (GSK189075)"]
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[{"$nulls":3},"Irinotecan hydrochloride","Lesinurad sodium","Oxytetracycline hydrochloride","Ceftriaxone Sodium","Larotrectinib","Amitriptyline","Dabigatran etexilate mesylate","S(-)-Propranolol hydrochloride","Fostemsavir","Olodaterol (BI 1744)"]
[]
[]
[]
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[{"$nulls":3},"Alpha-Estradiol","Dipivefrin Hydrochloride","Baloxavir","Tazobactam Sodium","Setmelanotide (RM-493)","Deserpidine","Rhamnose","Methyl methanesulfonate","Levamlodipine Besylate","H-Leu-Leu-OMe Hydrochloride"]
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[{"$nulls":3},"Glycerol phenylbutyrate","Propidium Iodide","Linalyl Acetate","Imidacloprid","Abaloparatide (BA058)","Isavuconazonium sulfate","Metrizoic acid","Esaxerenone (CS-3150)",null,"3,3'-Diaminobenzidine tetrahydrochloride"]
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[{"$nulls":3},"Varenicline","Saquinavir (Ro 31-8959)","Lithium Chloride","Betamethasone sodium phosphate",null,"Flumatinib (HH-GV-678)",null,"Gemifloxacin mesylate","p-Nitrobenzyl mesylate","Hematein"]
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[{"$nulls":3},"Iron Dextran","Imeglimin (EMD 387008) Hydrochloride","Taurocholic acid sodium salt","Hydrocortisone sodium succinate","Euquinine","Raclopride","Norgestimate","Nomegestrol Acetate","Dotinurad","Carbetocin Acetate"]
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[{"$nulls":3},"Gadoteridol","Bradykinin","Thioacetamide","Zinc acetate dihydrate","Fenoldopam","Invert sugar","Flecainide","Masitinib mesylate","Tandospirone","Bremelanotide Acetate"]
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[]
[]
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[{"$nulls":4},"Danicopan (ACH-4471)","Dianhydrogalactitol (VAL-083)","Suramin sodium salt","Antazoline Phosphate","Ganirelix acetate (Antagon)","Phenylephrine","Evocalcet","Clocortolone Pivalate","Sodium Pyruvate"]
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[{"$nulls":3},"Deucravacitinib (BMS-986165)","Iodixanol","Adagrasib (MRTX849)","Pirtobrutinib (LOXO-305)","Abarelix Acetate","Testosterone acetate","1-Naphthol","Naloxegol Oxalate","methylnaltrexone bromide","L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride"]
[]
[]
[]
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[{"$nulls":3},"Fezolinetant","Infigratinib Phosphate","Eprinomectin","Minoxidil"]
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[{"$nulls":3},"Palbociclib (PD-0332991) HCl","Dorzolamide HCl","Palbociclib (PD0332991) Isethionate","Levamisole hydrochloride","Lisinopril dihydrate","Tobramycin","Vancomycin HCl","Danofloxacin Mesylate","Abacavir sulfate","Cangrelor Tetrasodium"]
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[{"$nulls":3},"Pemetrexed (LY-231514) disodium","Mizoribine","Alendronate sodium trihydrate","Ticlopidine HCl","Fudosteine","NAD+","Hygromycin B","Amikacin disulfate","L-Arginine HCl (L-Arg)","Acamprosate Calcium"]
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[{"$nulls":3},"Gemcitabine (LY-188011) HCl","Polymyxin B sulphate","Cytarabine (U-19920A)","ATP disodium","Gabapentin","Methacycline HCl","Zanamivir","(R)-baclofen","Thiamine HCl (Vitamin B1)","isoleucine"]
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[{"$nulls":3},"Pamidronate Disodium","Teicoplanin","L-Glutamine","Procarbazine HCl","Kanamycin sulfate","Lomefloxacin HCl","Plerixafor (AMD3100) 8HCl","Caspofungin (MK-0991) Acetate","Cesium chloride","L-Leucine"]
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[{"$nulls":3},"Gabapentin HCl","Varenicline Tartrate (CP 526555-18)","Gadodiamide Hydrate","D-Cycloserine","Chondroitin sulfate","Amiloride HCl dihydrate","Geneticin (G418 Sulfate)","Creatinine","Ceftazidime","L-Citrulline"]
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[{"$nulls":3},"Galanthamine HBr","Perindopril Erbumine","Penicillamine","Sodium butyrate","Donepezil HCl","Oxacillin sodium monohydrate","Solifenacin succinate","Amikacin hydrate","Penicillin V potassium salt","L-Theanine"]
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[{"$nulls":3},"Granisetron HCl","Cidofovir","Etidronate","Taurine","Neostigmine Bromide","Neomycin sulfate","Palonosetron HCl","Tripelennamine HCl","Pirenzepine dihydrochloride","Sodium Demethylcantharidate"]
[]
[]
[]
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[{"$nulls":3},"DL-Glutamine","Netilmicin Sulfate","Eprazinone 2HCl","Ribostamycin Sulfate","Calcium Gluceptate","Eprodisate disodium","Choline bitartrate","Glycine","Pipemidic acid","Nylidrin Hydrochloride"]
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[{"$nulls":3},"L-SelenoMethionine","Bismuth Subcitrate Potassium","Amprolium HCl","Capreomycin Sulfate","Ceftazidime Pentahydrate","Pralidoxime chloride","D-(+)-Cellobiose","Manganese chloride","Methotrexate disodium","Cephradine monohydrate"]
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[{"$nulls":3},"Pemirolast potassium","Tetramisole HCl","Bacitracin","Proflavine Hemisulfate","Guanethidine Sulfate","Eflornithine (MDL-71782) hydrochloride hydrate","L-Glutamic acid monosodium salt","Sodium carbonate","Riboflavin phosphate sodium","Citicoline"]
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[{"$nulls":3},"Sodium Monofluorophosphate","Clodronate Disodium","Chloroquine diphosphate","Sodium ascorbate","Tolmetin Sodium","Captisol (SBE-β-CD)","Sodium ferulate","L(+)-Asparagine monohydrate","DL-Citrulline","UTP Trisodium Salt"]
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[{"$nulls":3},"Flavoxate HCl","Histamine Phosphate","Ceftriaxone disodium salt hemi (heptahydrate)","Apramycin Sulfate","Potassium Canrenoate","Glutathione","Danshensu","L-Threonine","Homotaurine","Loxoprofen Sodium"]
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[{"$nulls":3},"Dexamethasone Sodium Phosphate","Succinylcholine Chloride Dihydrate","Sodium Gluconate","Isepamicin Sulphate","Hydroxychloroquine Sulfate (NSC 4375)","L-Ornithine hydrochloride","Creatine phosphate disodium salt","Choline Glycerophosphate","Calcium folinate","Sodium succinate"]
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[{"$nulls":3},"Colistin Sulfate","Terbutaline Sulfate","Nefopam HCl","Micafungin (FK 463) Sodium","Dihydrostreptomycin sulfate","Cefradine","Glycylglycine","Timonacic","D-Pantethine","Guanethidine Monosulfate"]
[]
[]
[]
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[{"$nulls":3},"Spermine Tetrahydrochloride","L-Proline","Lodoxamide Tromethamine","Creatine monohydrate","Gadoxetate sodium","Eptifibatide Acetate","Desmopressin Acetate","Estramustine phosphate sodium","Potassium sorbate","L-Ornithine"]
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[{"$nulls":3},"β-Alanine","L-lysine","Edetate Trisodium","Thiamine pyrophosphate hydrochloride","Diquafosol Tetrasodium","Octreotide (SMS 201-995) acetate","Angiotensin II human Acetate","Spermine","Teriparatide Acetate","Tenofovir hydrate"]
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[{"$nulls":3},"Tobramycin sulfate","L-Alanine","Edetate calcium disodium","Malachite green","Rilmenidine Phosphate","Atosiban Acetate","Carperitide Acetate","Sodium stibogluconate","Felypressin Acetate","Gadodiamide"]
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[{"$nulls":3},"DL-Serine","L-aspartic Acid","pentetate calcium trisodium hydrate","(R)-Serine","Pemetrexed Disodium Hydrate","Oxytocin (Syntocinon)","(6-)ε-​Aminocaproic acid","HEPES","Zoledronic acid (ZOL 446)","Varenicline Hydrochloride"]
[null,"e","Empty","S5549","S5633","S5801","S6266","S9344","P1030","S3076","S4933","S3497","S5198","Empty"]
[{"$nulls":3},"DL-Arginine","L-methionine","Ala-Gln","(S)-Glutamic acid","DL-Methionine","Salmon Calcitonin Acetate","Foscarnet Sodium","Lithium carbonate","Gadobutrol","Sodium Etidronate"]
[null,"f","Empty","S5571","S5634","S5820","S6315","S9353","P1034","S4519","S3203","S4383","S5260","Empty"]
[{"$nulls":3},"L-Asparagine","L-arginine","L-Hydroxyproline","Sodium phytate hydrate","L-serine","Terlipressin Acetate","Citric acid trilithium salt tetrahydrate","D-Alanine","Bekanamycin","ATP"]
[null,"g","Empty","S5588","S5635","S5866","S6445","S9367","P1039","S5865","P1088","S4443","S5330","Empty"]
[{"$nulls":3},"Creatine","L-cysteine","Gastrodenol","Chlorophyllin (sodium copper salt)","Adenosine disodium triphosphate hydrate","Somatostatin Acetate","Hyaluronic acid","Lanreotide acetate","Piperazine adipate","Amikacin Sulfate Salt"]
[null,"h","Empty","S5628","S5660","S5867","S6460","P1004","P1049","S4986","S3096","S4494","S5956","Empty"]
[{"$nulls":3},"L-Valine","Clodronate disodium tetrahydrate","Bendazac L-lysine","Sugammadex (sodium)","Bivalirudin Trifluoroacetate","GHRP-2","Latamoxef sodium","L-Histidine monohydrochloride monohydrate","Methionine","Dexamethasone phosphate disodium"]
[]
[]
[]
[null,"Plate layout: L1300-40"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S5964","E0375","E0705","S5961","E4578","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Gatifloxacin hydrochloride","Ammonium ferric citrate","Flavin Adenine Dinucleotide Disodium","Prednisolone disodium phosphate","Trilaciclib dihydrochloride"]
[null,"b","Empty","S5968","P1104","E2638","E0178","S2542","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Kasugamycin hydrochloride hydrate","Glatiramer acetate","Tricine","Cysteamine bitartrate","Phenformin (NSC-756501) HCl"]
[null,"c","Empty","S6446","S6289","S3736","E4227","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Sodium citrate dihydrate","Gentamicin","Fondaparinux Sodium (Org 31540)","D-Cysteine"]
[null,"d","Empty","S9794","S6872","Empty","E4002","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Melittin","Merbromin",null,"Potassium D-gluconate"]
[null,"e","Empty","S5962","E0510","Empty","E4018","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"DL-Penicillamine","Cidofovir hydrate",null,"Ammonium sulfate"]
[null,"f","Empty","S6991","E0511","P1019","E2895","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Sodium Acetate","Framycetin sulphate","Cetrorelix Acetate","Sodium Bicarbonate"]
[null,"g","Empty","S6992","E0525","E0149","E4470","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Calcium chloride","Colistin","Papain","Potassium Chloride"]
[null,"h","Empty","S9489","E0532","S6482","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Sodium citrate","Menotropin","Fosphenytoin (disodium)"]
[]
[]
[]
[null,"Plate layout: L1300-41"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1023","S1464","S1724","S2110","S2476","S3064","S4126","S4930","S5712","S5031","Empty"]
[{"$nulls":3},"Erlotinib (OSI-774) HCl","Marbofloxacin","Paliperidone","Vinpocetine","Itraconazole (R 51211)","Ambroxol HCl","Retinyl (Vitamin A) Palmitate","Cetilistat","Zofenopril calcium","Sulfaquinoxaline sodium"]
[null,"b","Empty","S1046","S1507","S1837","S2150","S2530","S3636","S4142","S5018","S5908","S1502","Empty"]
[{"$nulls":3},"Vandetanib (ZD6474)","Irbesartan","Flubendazole","Neratinib (HKI-272)","7-Aminocephalosporanic acid","Cefadroxil hydrate","Clopidol","Mebhydrolin napadisylate","Garenoxacin","Cephalexin"]
[null,"c","Empty","S1211","S1509","S1851","S2152","S2582","S3721","S4156","S5035","S6632","S4482","Empty"]
[{"$nulls":3},"Imiquimod (R-837)","Norfloxacin","Oxibendazole","Sitafloxacin Hydrate","Trazodone HCl","Bilastine","Chlortetracycline HCl (NSC 13252)","6-Aminopenicillanic acid","Mirogabalin (DS-5565)","Palbociclib"]
[null,"d","Empty","S1288","S1615","S1929","S2206","S2597","S3770","S4218","S5232","S7128","S5799","Empty"]
[{"$nulls":3},"Camptothecin (NSC-100880)","Risperidone","Irsogladine","Fostamatinib (R788) disodium","Oseltamivir Phosphate","Sodium Aescinate","Amoxapine","Alectinib (CH5424802) hydrochloride","Tazemetostat (EPZ-6438)","Potassium guaiacolsulfonate hemihydrate"]
[null,"e","Empty","S1353","S1617","S1977","S2232","S2788","S3801","S4262","S5272","S7756","E0161","Empty"]
[{"$nulls":3},"Ketoconazole (R 41400)","Sulfapyridine","Sarafloxacin HCl","Ketanserin","Capmatinib (INCB28060)","Sodium Houttuyfonate","Ebastine","Toceranib phosphate","Indoximod (NLG-8189）","Bictegravir Sodium"]
[null,"f","Empty","S1371","S1642","S1986","S2251","S2920","S3821","S4605","S5499","S8229","E0524","Empty"]
[{"$nulls":3},"Cefoselis Sulfate","Methyldopa","Meclizine 2HCl","(-)-Huperzine A (HupA)","Mozavaptan","Nuciferine","Folic acid","Amantadine","Brigatinib (AP26113)","Spinosad"]
[null,"g","Empty","S1424","S1698","S2035","S2292","S3041","S3891","S4642","S5601","S8724","S9464","Empty"]
[{"$nulls":3},"Prazosin HCl","Torsemide","Epalrestat (ONO-2235)","Diosmin","Droxidopa","Vincamine","Dolutegravir Sodium","Balofloxacin Dihydrate","Lazertinib","Tranylcypromine Sulfate"]
[null,"h","Empty","S1463","S1707","S2047","S2424","S3059","S4033","S4654","S5677","S5098","E4160","Empty"]
[{"$nulls":3},"Ofloxacin","Eplerenone (CGP 30083)","Lornoxicam","Hypoxanthine","Enrofloxacin","Sennoside A","Netupitant","Xanthopterin Hydrate","Gefitinib hydrochloride","Glycyl-L-tyrosine"]
[]
[]
[]
[null,"Plate layout: L1300-42"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","E4468","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Cabotegravir Sodium"]
[null,"b","Empty","S2544","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Cefprozil hydrate"]
[null,"c","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"d","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"e","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"f","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"g","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"h","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[]
[]
[]
[null,"Plate layout: L1300-43"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1346","S4067","S2095","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Heparin sodium","Deferiprone","Fosinopril Sodium"]
[null,"b","Empty","S1428","S4153","S2050","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Risedronate Sodium","D-Phenylalanine","Strontium Ranelate"]
[null,"c","Empty","S1911","S4226","S5264","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Disodium Cromoglycate","Minocycline (CL 59806) HCl","L-5-Methyltetrahydrofolate calcium"]
[null,"d","Empty","S1982","S4694","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Adenine sulfate","Alosetron Hydrochloride"]
[null,"e","Empty","S2106","S5355","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Azasetron HCl","Piperaquine phosphate"]
[null,"f","Empty","S2562","S5695","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Hydralazine HCl","Icatibant Acetate"]
[null,"g","Empty","S3055","S8030","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Besifloxacin HCl","Plerixafor (AMD3100)"]
[null,"h","Empty","S3749","S5650","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Calcium gluconate monohydrate","Sodium Hyaluronate"]
[]
[]
[]
[null,"Plate layout: L1300-44"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4444","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Hypromellose"]
[null,"b","Empty","S3505","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Polidocanol"]
[null,"c","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
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[null,"f","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
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{"sheet":"L1300-FDA-3183 cpds","index":1,"n_rows":3184,"n_cols":27,"rows_kept":3184}
["Cat","Name","Plate Location","Rack Number","Formulation","Status","Pharmacopoeia","FDA NDA/ANDA","Indication","Target","Pathway","Information","M.w.","CAS Number","DMSO (mg/mL)Max Solubility","DMSO (mM)Max Solubility","Water (mg/mL)Max Solubility","Water (mM)Max Solubility","URL","Formula","Form","Synonyms","SMILES","ALogP","HBA_Count","HBD_Count","RotatableBond"]
["S1005","Axitinib (AG 013736)","a2","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia",202324,"Cancer","c-Kit,PDGFR,VEGFR","Protein Tyrosine Kinase","Axitinib (AG 013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively.",386.47,"319460-85-0",35,90.56,"<1",0,"http://selleckchem.com/products/Axitinib.html","C22H18N4OS","free base","AG 013736","CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=N[NH]3)\\C=C\\C4=CC=CC=N4",4.492,3,2,5]
["S1007","Roxadustat (FG-4592)","b2","L1300-01","in 10mM DMSO","CFDA",null,null,"Hematology","Ferroptosis,HIF","Angiogenesis","Roxadustat (FG-4592) is an HIF-α prolyl hydroxylase inhibitor in a cell-free assay, stabilizes HIF-2 and induces EPO production. Roxadustat potentiates RSL3 induced ferroptosis. Phase 3.",352.34,"808118-40-3",70,198.67,"<1",0,"http://selleckchem.com/products/fg-4592.html","C19H16N2O5","free base","ASP1517","CC1=NC(=C(O)C2=C1C=C(OC3=CC=CC=C3)C=C2)C(=O)NCC(O)=O",2.306,4,2,5]
["S1008","Selumetinib (AZD6244)","c2","L1300-01","in 10mM DMSO","FDA, NDC",null,"(NDA) 213756","Cancer","Apoptosis related,MEK","MAPK","Selumetinib (AZD6244, ARRY-142886) is a potent, highly selective MEK inhibitor with IC50 of 14 nM for MEK1 and Kd value of 530 nM for MEK2. It  also inhibits ERK1/2 phosphorylation with IC50 of 10 nM, no inhibition to p38α, MKK6, EGFR, ErbB2, ERK2, B-Raf, etc. Selumetinib suppresses cell proliferation, migration and trigger apoptosis. Phase 3.",457.68,"606143-52-6",91,198.83,"<1",0,"http://selleckchem.com/products/AZD6244.html","C17H15BrClFN4O3","free base","ARRY-142886","C[N]1C=NC2=C(F)C(=C(C=C12)C(=O)NOCCO)NC3=CC=C(Br)C=C3Cl",3.234,3,3,6]
["S1010","Nintedanib (BIBF 1120)","d2","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,205832,"Cancer/Respiratory Disease","FGFR,PDGFR,Src,VEGFR","Protein Tyrosine Kinase","Nintedanib (BIBF 1120, Intedanib, Vargatef, Ofev) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM in cell-free assays. Phase 3.",539.62,"656247-17-5",6,11.12,"<1",0,"http://selleckchem.com/products/BIBF1120.html","C31H33N5O4","free base","Intedanib, Vargatef, Ofev","COC(=O)C1=CC=C\\2C(=C1)NC(=O)C2=C(NC3=CC=C(C=C3)N(C)C(=O)CN4CCN(C)CC4)/C5=CC=CC=C5",2.965,4,2,8]
["S1011","Afatinib (BIBW2992)","e2","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,201292,"Cancer","Autophagy,EGFR,HER2","Protein Tyrosine Kinase","Afatinib (BIBW2992) inhibits EGFR/ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively. Afatinib induces autophagy.",485.94,"850140-72-6",97,199.61,"<1",0,"http://selleckchem.com/products/BIBW2992.html","C24H25ClFN5O3","Free Base","BIBW2992","CN(C)C/C=C/C(=O)NC1=CC2=C(NC3=CC=C(F)C(=C3)Cl)N=CN=C2C=C1OC4CCOC4",3.917,5,2,8]
["S1013","Bortezomib (PS-341)","f2","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","USP;Martindale:The Extra Pharmacopoeia","204332,204405,205004,205160,205533,208392,208460,208645,209191,210615,210824","Cancer","Autophagy,Cathepsin B,Cysteine Protease,ERK,NF-κB,Proteasome","Proteases","Bortezomib (PS-341, Velcade, LDP-341, MLM341, NSC 681239) is a potent 20S proteasome inhibitor with Ki of 0.6 nM. It exhibits favorable selectivity towards tumor cells over normal cells. Bortezomib (PS-341) inhibits NF-κB and induces ERK phosphorylation to suppress cathepsin B and inhibit the catalytic process of autophagy in ovarian cancer and other solid tumors.",384.24,"179324-69-7",76,197.79,"<1",0,"http://selleckchem.com/products/Bortezomib.html","C19H25BN4O4","Free Base","Velcade, LDP-341, MLM341, NSC 681239,PS-341","CC(C)CC(NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)B(O)O",2.183,4,2,9]
["S1014","Bosutinib (SKI-606)","g2","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,203341,"Cancer/Hematology","Autophagy,Bcr-Abl,ERK,S6 Kinase,Src,STAT","Angiogenesis","Bosutinib (SKI-606) is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM in cell-free assays, respectively. Bosutinib also effectively decreases the activity of PI3K/AKT/mTOR, MAPK/ERK and JAK/STAT3 signaling pathways by blocking the phosphorylation levels of p-ERK, p-S6, and p-STAT3. Bosutinib promotes autophagy.",530.45,"380843-75-4",100,188.52,"<1",0,"http://selleckchem.com/products/Bosutinib.html","C26H29Cl2N5O3","free base","SKI-606","COC1=C(Cl)C=C(Cl)C(=C1)NC2=C(C=NC3=CC(=C(OC)C=C23)OCCCN4CCN(C)CC4)C#N",4.883,4,1,9]
["S1021","Dasatinib (BMS-354825)","h2","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia",202103,"Cancer/Hematology","Apoptosis related,Autophagy,Bcr-Abl,c-Kit,Src","Angiogenesis","Dasatinib (BMS-354825) is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively. Dasatinib induces autophagy and apoptosis with anti-tumor activity.",488.01,"302962-49-8",98,200.82,"<1",0,"http://selleckchem.com/products/Dasatinib.html","C22H26ClN7O2S","free base","BMS-354825","CC1=NC(=CC(=N1)N2CCN(CCO)CC2)NC3=NC=C(S3)C(=O)NC4=C(Cl)C=CC=C4C",3.439,4,3,7]
["S1022","Ridaforolimus (Deforolimus, MK-8669)","a3","L1300-01","in 10mM DMSO","DMF",null,null,"cancer","FKBP,mTOR","PI3K/Akt/mTOR","Ridaforolimus (Deforolimus, MK-8669, AP23573) is a selective mTOR inhibitor with IC50 of 0.2 nM in HT-1080 cell line; while not classified as a prodrug, mTOR inhibition and FKBP12 binding is similar to rapamycin. Phase 3.",990.21,"572924-54-0",198,199.96,"<1",0,"http://selleckchem.com/products/Deforolimus.html","C53H84NO14P","free base","AP23573","COC1CC(CCC1O[P](C)(C)=O)CC(C)C2CC(=O)C(C)\\C=C(C)\\C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC",6.303,12,1,8]
["S1025","Gefitinib (ZD1839)","b3","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","EP9.3;BP2019;IP2010","206995,021399","Cancer/Respiratory Disease","Apoptosis related,Autophagy,EGFR","Protein Tyrosine Kinase","Gefitinib (ZD-1839, Iressa) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively. Gefitinib promotes autophagy and apoptosis of lung cancer cells via blockade of the PI3K/AKT/mTOR pathway.",446.9,"184475-35-2",89,199.15,"<1",0,"http://selleckchem.com/products/Gefitinib.html","C22H24ClFN4O3","free base","Iressa,ZD1839","COC1=C(OCCCN2CCOCC2)C=C3C(=NC=NC3=C1)NC4=CC=C(F)C(=C4)Cl",4.203,5,1,8]
["S1026","Imatinib (STI571) Mesylate","c3","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","EP9.2;BP2019;IP2010;Martindale:The Extra Pharmacopoeia","078340,079179,204285,204644,205990,206547,207495,207586,207818,208302,208429","Cancer/Hematology","Autophagy,Bcr-Abl,c-Kit,PDGFR","Protein Tyrosine Kinase","Imatinib (STI571, CGP057148B, Gleevec) Mesylate is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib Mesylate (STI571) induces autophagy.",589.71,"220127-57-1",118,200.1,118,200.1,"http://selleckchem.com/products/Imatinib-Mesylate.html","C29H31N7O.CH4SO3","Mesylate","Gleevec, Glivec, CGP-57148B,STI571","CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC=C(C)C(=C3)NC4=NC=CC(=N4)C5=CC=CN=C5.C[S](O)(=O)=O",3.806,4,2,7]
["S1028","Lapatinib (GW-572016) Ditosylate","d3","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","022059","Cancer","EGFR,HER2","Protein Tyrosine Kinase","Lapatinib (GW-572016) Ditosylate is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively.",925.46,"388082-77-7",100,108.05,"<1",0,"http://selleckchem.com/products/Lapatinib-Ditosylate.html","C29H26ClFN4O4S.2C7H8O3S","Ditosylat","GW-572016","CC1=CC=C(C=C1)[S](O)(=O)=O.CC2=CC=C(C=C2)[S](O)(=O)=O.C[S](=O)(=O)CCNCC3=CC=C(O3)C4=CC=C5N=CN=C(NC6=CC=C(OCC7=CC=CC(=C7)F)C(=C6)Cl)C5=C4",9.339,6,2,13]
["S1029","Lenalidomide (CC-5013)","e3","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","021880","Cancer","Apoptosis related,Caspase,E3 Ligase ,E3 ligase Ligand,TNF-alpha,VEGFR","Ubiquitin","Lenalidomide (CC-5013) is a TNF-α secretion inhibitor with IC50 of 13 nM in PBMCs. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide promotes cleaved caspase-3 expression and inhibit VEGF expression and induces apoptosis.",259.26,"191732-72-6",52,200.57,"<1",0,"https://www.selleckchem.com/products/lenalidomide-s1029.html","C13H13N3O3","free base","CC-5013","NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1",-0.515,3,2,1]
["S1030","Panobinostat (LBH589)","f3","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia",205353,"Cancer","Apoptosis related,Autophagy,HDAC,HIV Protease","Epigenetics","Panobinostat (LBH589, NVP-LBH589) is a novel broad-spectrum HDAC inhibitor with IC50 of 5 nM in a cell-free assay. Panobinostat (LBH589) induces autophagy and apoptosis. Panobinostat effectively disrupts HIV latency in vivo. Phase 3.",349.43,"404950-80-7",69,197.46,"<1",0,"http://selleckchem.com/products/LBH-589.html","C21H23N3O2","Free Base","NVP-LBH589","CC1=C(CCNCC2=CC=C(\\C=C\\C(=O)NO)C=C2)C3=C([NH]1)C=CC=C3",3.194,1,3,7]
["S1033","Nilotinib (AMN-107)","g3","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","EP9.8;Martindale:The Extra Pharmacopoeia","022068","Cancer/Hematology","AMPK,Autophagy,Bcr-Abl","Angiogenesis","Nilotinib (AMN-107) is a selective Bcr-Abl inhibitor with IC50 less than 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.",529.52,"641571-10-0",27,50.99,"<1",0,"http://selleckchem.com/products/Nilotinib.html","C28H22F3N7O","free base","AMN-107","CC1=C[N](C=N1)C2=CC(=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C)C(=C3)NC4=NC=CC(=N4)C5=CN=CC=C5",5.084,5,2,7]
["S1035","Pazopanib HCl (GW786034 HCl)","h3","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"022465","Angiology/Cancer","Autophagy,c-Kit,CSF-1R,FGFR,PDGFR,VEGFR","Protein Tyrosine Kinase","Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively. Pazopanib induces autophagic Type II cell death.",473.98,"635702-64-6",17,35.87,"<1",0,"http://selleckchem.com/products/Pazopanib-Hydrochloride.html","C21H23N7O2S.HCl","Hydrochloride","GW786034 HCl","Cl.C[N]1N=C2C=C(C=CC2=C1C)N(C)C3=NC(=NC=C3)NC4=CC=C(C)C(=C4)[S](N)(=O)=O",4.123,5,2,5]
["S1039","Rapamycin (AY-22989)","a4","L1300-01","in 10mM DMSO","DMF",null,null,"Immunology","Antineoplastic and Immunosuppressive Antibiotics,Autophagy,mTOR","PI3K/Akt/mTOR","Rapamycin (AY-22989, Rapamune, Sirolimus, NSC-2260804,AY-22989) is a specific mTOR inhibitor with IC50 of ~0.1 nM HEK293 cells.",914.18,"53123-88-9",20,21.88,"<1",0,"http://selleckchem.com/products/Rapamycin.html","C51H79NO13","free base","Rapamune, Sirolimus, NSC-2260804,AY-22989","COC1CC(CCC1O)CC(C)C2CC(=O)C(C)\\C=C(/C)C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC",6.295,10,2,6]
["S1040","Sorafenib (BAY 43-9006) tosylate","b4","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","021923","Cancer","Apoptosis related,Autophagy,c-Kit,Ferroptosis,FGFR,FLT3,PDGFR,Raf,VEGFR","MAPK","Sorafenib tosylate (BAY 43-9006 tosylate,NSC-724772 tosylate)  is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib Tosylate inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib Tosylate induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.",637.03,"475207-59-1",127,199.36,0.01,0.02,"http://selleckchem.com/products/Sorafenib-Tosylate.html","C21H16ClF3N4O3.C7H8O3S","Tosylate","BAY 43-9006 tosylate,NSC-724772 tosylate","CNC(=O)C1=CC(=CC=N1)OC2=CC=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2.CC4=CC=C(C=C4)[S](O)(=O)=O",5.824,4,3,7]
["S1042","Sunitinib (SU11248) malate","c4","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia",201275,"Cancer","Apoptosis related,c-Kit,IRE1,Mitophagy,PDGFR,VEGFR","Protein Tyrosine Kinase","Sunitinib (SU11248) malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM in cell-free assays, and also inhibits c-Kit. Sunitinib Malate effectively inhibits autophosphorylation of Ire1α. Sunitinib Malate increases both death receptor and mitochondrial-dependent apoptosis.",532.56,"341031-54-7",15,28.17,"<1",0,"http://selleckchem.com/products/Sunitinib-Malate-(Sutent).html","C22H27FN4O2.C4H6O5","Malate","N/A","CCN(CC)CCNC(=O)C1=C(C)[NH]C(=C1C)/C=C/2C(=O)NC3=CC=C(F)C=C23.OC(CC(O)=O)C(O)=O",-1.049,4,4,10]
["S1044","Temsirolimus (CCI-779)","d4","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","203153,207383","Cancer","Apoptosis related,Autophagy,mTOR","PI3K/Akt/mTOR","Temsirolimus (CCI-779, NSC 683864) is a specific mTOR inhibitor with IC50 of 1.76 μM in a cell-free assay. Temsirolimus induces autophagy and apoptosis.",1030.29,"162635-04-3",67,65.03,"<1",0,"http://selleckchem.com/products/Temsirolimus.html","C56H87NO16","free base","NSC 683864,CCI-779","COC1CC(CCC1OC(=O)C(C)(CO)CO)CC(C)C2CC(=O)C(C)\\C=C(C)\\C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC",6.039,12,3,11]
["S1047","Vorinostat (SAHA)","e4","L1300-01","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia","021991","Cancer","Autophagy,HDAC,HPV","Epigenetics","Vorinostat (SAHA,MK0683, Suberoylanilide hydroxamic acid, Zolinza) is an HDAC inhibitor with IC50 of ~10 nM in a cell-free assay. Vorinostat abrogates productive HPV-18 DNA amplification.",264.3,"149647-78-9",52,196.75,"<1",0,"http://selleckchem.com/products/Vorinostat-saha.html","C14H20N2O3","free base","SAHA,MK0683, Suberoylanilide hydroxamic acid, Zolinza","ONC(=O)CCCCCCC(=O)NC1=CC=CC=C1",2.005,2,2,8]
["S1053","Entinostat (MS-275)","f4","L1300-01","in 10mM DMSO","DMF",null,null,"Cancer","Apoptosis related,Autophagy,HDAC","Epigenetics","Entinostat (MS-275, SNDX-275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM in cell-free assays, compared with HDACs 4, 6, 8, and 10. Entinostat induces autophagy and apoptosis. Phase 3.",376.41,"209783-80-2",75,199.25,"<1",0,"http://selleckchem.com/products/MS-275.html","C21H20N4O3","free base","SNDX-275","NC1=CC=CC=C1NC(=O)C2=CC=C(CNC(=O)OCC3=CN=CC=C3)C=C2",2.071,4,3,7]
["S1055","Enzastaurin (LY317615)","g4","L1300-01","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cancer","PKC","TGF-beta/Smad","Enzastaurin (LY317615) is a potent PKCβ selective inhibitor with IC50 of 6 nM in cell-free assays, 6- to 20-fold selectivity against PKCα, PKCγ and PKCε. Phase 3.",515.61,"170364-57-5",30,58.18,"<1",0,"http://selleckchem.com/products/Enzastaurin.html","C32H29N5O2","free base","N/A","C[N]1C=C(C2=CC=CC=C12)C3=C(C(=O)NC3=O)C4=C[N](C5CCN(CC5)CC6=NC=CC=C6)C7=CC=CC=C47",4.32,3,1,5]
["S1060","Olaparib (AZD2281)","h4","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","206162,208558","Cancer","Autophagy,Mitophagy,PARP","DNA Damage/DNA Repair","Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1. Olaparib induces significant autophagy that is associated with mitophagy in cells with BRCA mutations.",434.46,"763113-22-0",86,197.95,0,0,"http://selleckchem.com/products/AZD2281(Olaparib).html","C24H23FN4O3","free base","Ku-0059436","FC1=C(C=C(CC2=NNC(=O)C3=C2C=CC=C3)C=C1)C(=O)N4CCN(CC4)C(=O)C5CC5",2.127,4,1,4]
["S1064","Masitinib (AB1010)","a5","L1300-01","in 10mM DMSO","DMF,EMA",null,null,"Cancer","c-Kit,PDGFR","Protein Tyrosine Kinase","Masitinib is a novel inhibitor for Kit (c-Kit) and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms. Phase 3.",498.64,"790299-79-5",100,200.55,"<1",0,"http://selleckchem.com/products/Masitinib-(AB1010).html","C28H30N6OS","free base","N/A","CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC(=C(C)C=C3)NC4=NC(=CS4)C5=CC=CN=C5",4.475,3,2,7]
["S1068","Crizotinib (PF-02341066)","b5","L1300-01","in 10mM DMSO","FDA,EMA,NDC,PMDA",null,202570,"Cancer/Respiratory Disease","ALK,Autophagy,c-Met,ROS1","Protein Tyrosine Kinase","Crizotinib (PF-02341066) is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM in cell-based assays, respectively. It is also a potent ROS1 inhibitor with Ki value less than 0.025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines.",450.34,"877399-52-5",9,19.98,"<1",0,"http://selleckchem.com/products/PF-2341066.html","C21H22Cl2FN5O","free base","PF-02341066","CC(OC1=C(N)N=CC(=C1)C2=C[N](N=C2)C3CCNCC3)C4=C(Cl)C=CC(=C4Cl)F",3.693,3,2,5]
["S1082","Vismodegib (GDC-0449)","c5","L1300-01","in 10mM DMSO","FDA,EMA,NDC",null,203388,"Cancer/Respiratory Disease","Hedgehog/Smoothened","Stem Cells & Wnt","Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay.",421.3,"879085-55-9",84,199.38,"<1",0,"http://selleckchem.com/products/GDC-0449.html","C19H14Cl2N2O3S","free base","GDC-0449","C[S](=O)(=O)C1=CC=C(C(=C1)Cl)C(=O)NC2=CC(=C(Cl)C=C2)C3=NC=CC=C3",4.265,4,1,4]
["S1085","Belinostat (PXD101)","d5","L1300-01","in 10mM DMSO","FDA,DMF,NDC",null,206256,"Cancer/Hematology","Autophagy,HDAC","Epigenetics","Belinostat (PXD101, NSC726630, PX-105684) is a novel HDAC inhibitor with IC50 of 27 nM in a cell-free assay, with activity demonstrated in cisplatin-resistant tumors. Belinostat (PXD101) induces autophagy.",318.35,"866323-14-0",64,201.04,"<1",0,"http://selleckchem.com/products/Belinostat.html","C15H14N2O4S","free base","PXD101,NSC726630, PX-105684","ONC(=O)/C=C/C1=CC(=CC=C1)[S](=O)(=O)NC2=CC=CC=C2",1.8,3,2,5]
["S1098","Rucaparib (AG-014699) phosphate","e5","L1300-01","in 10mM DMSO","FDA,EMA,NDC",null,209115,"Cancer","PARP","DNA Damage/DNA Repair","Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains. Phase 3.",421.36,"459868-92-9",84,199.35,"<1",0,"http://selleckchem.com/products/AG-014699.html","C19H18FN3O.H3PO4","Phosphate","PF-01367338","CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=CC(=CC(=C34)[NH]2)F.O[P](O)(O)=O",2.49,1,3,3]
["S1119","Cabozantinib (BMS-907351)","f5","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"208692,203756","Cancer","Apoptosis related,Axl,c-Met,VEGFR","Protein Tyrosine Kinase","Cabozantinib (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively. Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway.",501.51,"849217-68-1",100,199.4,"<1",0,"http://selleckchem.com/products/XL184.html","C28H24FN3O5","Free Base","XL184,BMS-907351","COC1=CC2=C(C=C1OC)C(=CC=N2)OC3=CC=C(NC(=O)C4(CC4)C(=O)NC5=CC=C(F)C=C5)C=C3",4.342,6,2,8]
["S1120","Everolimus (RAD001)","g5","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","EP9.7;Martindale:The Extra Pharmacopoeia","206133,207486,207934,210050,210130","Cancer","Apoptosis related,Autophagy,FKBP,mTOR","PI3K/Akt/mTOR","Everolimus (RAD001, SDZ-RAD, Afinitor) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM in a cell-free assay. Everolimus induces cell apoptosis and autophagy and inhibits tumor cells proliferation.",958.22,"159351-69-6",100,104.36,"<1",0,"http://selleckchem.com/products/Everolimus(RAD001).html","C53H83NO14","free base","RAD001,SDZ-RAD, Afinitor","COC1CC(CCC1OCCO)CC(C)C2CC(=O)C(C)\\C=C(C)\\C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC",6.164,11,2,9]
["S1137","Malotilate","h5","L1300-01","in 10mM DMSO","CFDA,DMF,PMDA","Martindale:The Extra Pharmacopoeia",null,"Metabolic Disease","Lipoxygenase","Metabolism","Malotilate (NKK105) is a drug used for the treatment of liver cirrhosis. Malotilate is a liver protein metabolism improved compound, which selectively inhibit the 5-lipoxygenase.",288.38,"59937-28-9",58,201.12,"<1",0,"http://selleckchem.com/products/Malotilate.html","C12H16O4S2","free base","NKK105","CC(C)OC(=O)C(C(=O)OC(C)C)=C1SC=CS1",2.363,4,0,6]
["S1144","Ivacaftor (VX-770)","a6","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"203188,207925,206038,211358,210491","Respiratory Disease","CFTR","Transmembrane Transporters","Ivacaftor (VX-770) is a selective potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM in fisher rat thyroid cells, respectively.",392.49,"873054-44-5",78,198.73,"<1",0,"http://selleckchem.com/products/VX-770.html","C24H28N2O3","free base","VX-770","CC(C)(C)C1=CC(=C(NC(=O)C2=CNC3=C(C=CC=C3)C2=O)C=C1O)C(C)(C)C",4.516,2,3,4]
["S1148","Docetaxel (RP56976)","b6","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","022234,022312,022534,201195,201525,202356,203170,203551,203877,204193,205934,206177,207252,207563,208137,208859,209634,209640,210072,210327,210848","Cancer/Respiratory Disease","Microtubule Associated","Cytoskeletal Signaling","Docetaxel (RP56976, NSC 628503), an analog of paclitaxel, is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules.",807.88,"114977-28-5",100,123.78,"<1",0,"http://selleckchem.com/products/Docetaxel(Taxotere).html","C43H53NO14","Free Base","NSC 628503,RP56976","CC(=O)OC12COC1CC(O)C3(C)C2C(OC(=O)C4=CC=CC=C4)C5(O)CC(OC(=O)C(O)C(NC(=O)OC(C)(C)C)C6=CC=CC=C6)C(=C(C(O)C3=O)C5(C)C)C",2.586,10,4,13]
["S1150","Paclitaxel (NSC 125973)","c6","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.7;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","075184,075190,075278,075297,075436,076131,076233,077413,077574,078167,090130,091540,205720","Cancer/Respiratory Disease","ADC Cytotoxin,Antineoplastic and Immunosuppressive Antibiotics,Autophagy,Microtubule Associated","Cytoskeletal Signaling","Paclitaxel (NSC 125973, PTX, Taxol, Onxal, Abraxane) is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.",853.91,"33069-62-4",171,200.26,"<1",0,"http://selleckchem.com/products/Paclitaxel(Taxol).html","C47H51NO14","free base","PTX, Taxol, Onxal, Abraxane,NSC 125973","CC(=O)OC1C(=O)C2(C)C(O)CC3OCC3(OC(C)=O)C2C(OC(=O)C4=CC=CC=C4)C5(O)CC(OC(=O)C(O)C(NC(=O)C6=CC=CC=C6)C7=CC=CC=C7)C(=C1C5(C)C)C",3.055,11,3,14]
["S1156","Capecitabine (RO 09-1978)","d6","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","090943,091649,200483,202593,204741,207456,207652,209365,210604","Cancer","Apoptosis related,DNA/RNA Synthesis","DNA Damage/DNA Repair","Capecitabine (RO 09-1978) is a tumor-selective fluoropyrimidine carbamate, which achieves higher intratumoral 5-FU level with lower toxicity than 5-FU. Capecitabine treatment of HCT-15 cells causes condensation of DNA and induces apoptosis.",359.35,"154361-50-9",72,200.36,6,16.7,"http://selleckchem.com/products/Capecitabine(Xeloda).html","C15H22FN3O6","free base","RO 09-1978","CCCCCOC(=O)NC1=NC(=O)N(C=C1F)C2OC(C)C(O)C2O",0.82,5,3,7]
["S1162","Pretomanid (PA-824)","e6","L1300-01","in 10mM DMSO","FDA,NDC",null,"212862","Infection","Bacterial","Microbiology","PA-824 is an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM.Phase 2.",359.26,"187235-37-6",72,200.41,"<1",0,"http://selleckchem.com/products/pa-824.html","C14H12F3N3O5","free base","N/A","[O-][N+](=O)C1=C[N]2CC(COC2=N1)OCC3=CC=C(OC(F)(F)F)C=C3",4.301,4,0,6]
["S1164","Lenvatinib (E7080)","f6","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,206947,"Cancer","c-Kit,c-RET,FGFR,PDGFR,VEGFR","Protein Tyrosine Kinase","Lenvatinib (E7080) is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β in cell-free assays. Lenvatinib (E7080) also inhibits FGFR1-4, PDGFR, Kit (c-Kit), RET (c-RET), and shows potent antitumor activities. Phase 3.",426.85,"417716-92-8",40,93.71,"<1",0,"http://selleckchem.com/products/E7080.html","C21H19ClN4O4","free base","N/A","COC1=C(C=C2C(=CC=NC2=C1)OC3=CC(=C(NC(=O)NC4CC4)C=C3)Cl)C(N)=O",2.832,5,3,6]
["S1168","Valproic Acid (NSC 93819) sodium salt","g6","L1300-01","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","070195,070431,070631,070868,073178,073229,073484,074060,075379,075782,077105,077960,090517,091037","Neurological Disease/Infection/Psychotic disorders","Autophagy,GABA Receptor,HDAC,Mitophagy,Notch,PGC-1α","Neuronal Signaling","Valproic Acid sodium salt (NSC 93819, Sodium valproate) is a HDAC inhibitor by selectively inducing proteasomal degradation of HDAC2, used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. Valproic acid induces Notch1 signaling in small cell lung cancer (SCLC) cells. Valproic acid is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α.",166.19,"1069-66-5",33,198.57,33,198.57,"http://selleckchem.com/products/Sodium-valproate.html","C8H15NaO2","Sodium salt","Sodium valproate,NSC 93819,2-Propylpentanoic Acid","CCCC(CCC)C(=O)O[Na]",1.275,0,0,5]
["S1178","Regorafenib (BAY 73-4506)","h6","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","EP9.8","203085,204369","Cancer","Autophagy,c-Kit,c-RET,PDGFR,Raf,VEGFR","Protein Tyrosine Kinase","Regorafenib (BAY 73-4506,Fluoro-Sorafenib, Resihance, Stivarga) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively. Regorafenib induces autophagy.",482.82,"755037-03-7",97,200.9,"<1",0,"http://selleckchem.com/products/BAY-73-4506.html","C21H15ClF4N4O3","free base","Fluoro-Sorafenib, Resihance, Stivarga,BAY 73-4506","CNC(=O)C1=CC(=CC=N1)OC2=CC(=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2)F",4.381,4,3,6]
["S1183","Danoprevir (ITMN-191)","a7","L1300-01","in 10mM DMSO","CFDA",null,null,"Infection/Inflammation","COVID-19,HCV Protease","Proteases","Danoprevir (ITMN-191, RG7227) is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. Phase 2.",731.83,"850876-88-9",144,196.77,"<1",0,"http://selleckchem.com/products/Danoprevir.html","C35H46FN5O9S","free base","RG7227","CC(C)(C)OC(=O)NC1CCCCC\\C=C/C2CC2(NC(=O)C3CC(CN3C1=O)OC(=O)N4CC5=C(C4)C(=CC=C5)F)C(=O)N[S](=O)(=O)C6CC6",2.922,9,3,8]
["S1185","Ritonavir (ABT-538)","b7","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","022282,205508,206041,205425,207407,079074,090371,090471,091202,091203,091677,204739,210540,202573,202738,203759,204587,205040,205801,206614,208890","Infection","Apoptosis related,COVID-19,HIV Protease,P450 (e.g. CYP17)","Proteases","Ritonavir (ABT-538, A 84538, RTV, Norvir, Norvir Softgel) is a Cytochrome P450 3A and Protease Inhibitor; Also inhibits Cytochrome P450 2D6, P-Glycoprotein and induces Cytochrome P450 2C19, Cytochrome P450 1A2, Cytochrome P450 2C9, Cytochrome P450 2B6 and UDP Glucuronosyltransferases. Ritonavir induces apoptosis.",720.94,"155213-67-5",100,138.71,"<1",0,"http://selleckchem.com/products/Ritonavir.html","C37H48N6O5S2","free base","ABT-538,A 84538, RTV, Norvir, Norvir Softgel","CC(C)C(NC(=O)N(C)CC1=CSC(=N1)C(C)C)C(=O)NC(CC(O)C(CC2=CC=CC=C2)NC(=O)OCC3=CN=CS3)CC4=CC=CC=C4",4.978,6,4,18]
["S1188","Anastrozole (ZD-1033)","c7","L1300-01","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.3;BP2019;IP2010;Martindale:The Extra Pharmacopoeia","078058,078322,078485,078921,078944,078984,079007,079220,090088,090568,090732,091051,091164,091177,091242,091331,200654,206037","Cancer","Aromatase","Endocrinology & Hormones","Anastrozole (Arimidex,ZD-1033) is a third-generation nonsteroidal selective aromatase inhibitor. It may offer greater selectivity compared with other aromatase inhibitors, being without any intrinsic endocrine effects and with no apparent effect on the synthesis of adrenal steroids.",293.37,"120511-73-1",59,201.11,"<1",0,"http://selleckchem.com/products/Anastrozole.html","C17H19N5","free base","Arimidex,ZD-1033","CC(C)(C#N)C1=CC(=CC(=C1)C[N]2C=NC=N2)C(C)(C)C#N",2.965,2,0,4]
["S1189","Aprepitant (MK-0869)","d7","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","090999,207777","Gastroenterology","CSF-1R,HIV,Interleukins,Neurokinin Receptor,TNF-alpha","Neuronal Signaling","Aprepitant (MK-0869, L-754030, Emend) is a potent and selective neurokinin-1 receptor antagonist with IC50 of 0.1 nM. Aprepitant reduces levels of pro-inflammatory cytokines including G-CSF, IL-6, IL-8 and TNFα. Aprepitant inhibits HIV infection of human macrophages.",534.43,"170729-80-3",107,200.21,"<1",0,"http://selleckchem.com/products/Aprepitant.html","C23H21F7N4O3","free base","MK-0869, L-754030, Emend","CC(OC1OCCN(CC2=NNC(=O)N2)C1C3=CC=C(F)C=C3)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F",4.635,4,2,8]
["S1190","Bicalutamide (ICI-176334)","e7","L1300-01","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","076932,077973,077995,078285,078575,078634,078917,079045,079089,079110,079185,091011,200274","Cancer","Androgen Receptor,Autophagy","Endocrinology & Hormones","Bicalutamide (ICI-176334) is an androgen receptor (AR) antagonist with IC50 of 0.16 μM in LNCaP/AR(cs)cell line. Bicalutamide promotes autophagy.",430.37,"90357-06-5",86,199.83,"<1",0,"http://selleckchem.com/products/Bicalutamide(Casodex).html","C18H14F4N2O4S","free base","ICI-176334","CC(O)(C[S](=O)(=O)C1=CC=C(F)C=C1)C(=O)NC2=CC=C(C#N)C(=C2)C(F)(F)F",2.926,3,1,6]
["S1191","Fulvestrant (ICI-182780)","f7","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","USP42-NF37;BP2019;Martindale:The Extra Pharmacopoeia","205935,207754,210044,210326","Cancer","Apoptosis related,Autophagy,Estrogen/progestogen Receptor","Endocrinology & Hormones","Fulvestrant (ICI-182780, ZD 9238, ZM 182780) is an estrogen receptor (ER) antagonist with IC50 of 0.94 nM in a cell-free assay. Fulvestrant also induces autophagy and apoptosis and has antitumor activity.",606.77,"129453-61-8",100,164.81,"<1",0,"http://selleckchem.com/products/Fulvestrant.html","C32H47F5O3S","free base","ICI-182780, ZD 9238, ZM 182780","CC12CCC3C(C(CCCCCCCCC[S](=O)CCCC(F)(F)C(F)(F)F)CC4=C3C=CC(=C4)O)C1CCC2O",8.437,1,2,15]
["S1192","Raltitrexed","g7","L1300-01","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Cancer","DNA/RNA Synthesis,Thymidylate Synthase","DNA Damage/DNA Repair","Raltitrexed (ZD-1694) is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth.",458.49,"112887-68-0",91,198.48,"<1",0,"http://selleckchem.com/products/Raltitrexed.html","C21H22N4O6S","free base","ZD-1694, ICI-D1694, D1694","CN(CC1=CC2=C(C=C1)N=C(C)NC2=O)C3=CC=C(S3)C(=O)NC(CCC(O)=O)C(O)=O",1.528,5,2,9]
["S1193","Thalidomide (K17)","h7","L1300-01","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA","USP42-NF37 ;Martindale:The Extra Pharmacopoeia","020785,021430","Neurological Disease","E3 Ligase ,E3 ligase Ligand,TNF-alpha","Ubiquitin","Thalidomide (K17) was introduced as a sedative drug, immunomodulatory agent and also is investigated for treating symptoms of many cancers. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1.",258.23,"50-35-1",51,197.5,"<1",0,"http://selleckchem.com/products/Thalidomide.html","C13H10N2O4","free base","K17","O=C1CCC(N2C(=O)C3=C(C=CC=C3)C2=O)C(=O)N1",0.097,4,1,1]
["S1196","Exemestane (FCE 24304)","a8","L1300-01","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","077431,200898,202602,203315,206421,209208,210323,211031","Cancer","Aromatase","Endocrinology & Hormones","Exemestane (Aromasin,FCE24304, PNU155971,EXE) is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively.",296.4,"107868-30-4",54,182.19,"<1",0,"http://selleckchem.com/products/Exemestane.html","C20H24O2","free base","Aromasin,FCE24304, PNU155971,EXE","CC12CCC3C(CC(=C)C4=CC(=O)C=CC34C)C1CCC2=O",3.606,2,0,0]
["S1197","Finasteride","b8","L1300-01","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","076340,76436,76437,76511,76905,77251,77335,77578,77914,78161,78341,78371,78900,90060,90061,90121,90507,90508,91643,203687,204304,207750","Endocrinology","5-alpha Reductase","Endocrinology & Hormones","Finasteride (MK-906) is a potent, reversible inhibitor of the rat type 1 5 alpha-reductase with Ki of 10.2 nM, used in the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB).",372.54,"98319-26-7",75,201.32,"<1",0,"http://selleckchem.com/products/Finasteride.html","C23H36N2O2","free base","MK-906","CC(C)(C)NC(=O)C1CCC2C3CCC4NC(=O)C=CC4(C)C3CCC12C",3.174,2,2,2]
["S1199","Cladribine (RWJ 26251)","c8","L1300-01","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;All compounds are not protected by patents","075405,076571,200510","Cancer/Hematology","Adenosine Deaminase,DNA/RNA Synthesis","Neuronal Signaling","Cladribine (RWJ 26251, Leustatin, 2-CdA, 2-chlorodeoxyadenosine, 2-Chloro-2′-deoxyadenosine, CldAdo, Jk 6251, NSC 105014) is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43 μM, 0.75 μM, and 0.18 μM, respectively.",285.69,"4291-63-8",57,199.52,"<1",0,"http://selleckchem.com/products/Cladribine.html","C10H12ClN5O3","free base","Leustatin,2-CdA,2-Chloro-2′-deoxyadenosine,CldAdo,Jk 6251,NSC 105014,RWJ 26251","NC1=NC(=NC2=C1N=C[N]2C3CC(O)C(CO)O3)Cl",-0.259,4,3,2]
["S1200","Decitabine (NSC 127716)","d8","L1300-01","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia","202969,203131,203475,204607,205582,206033,207100,208601,209056,210756","Cancer/Hematology","Apoptosis related,DNA Methyltransferase,Nucleoside Analog/Antimetabolite","Epigenetics","Decitabine (Deoxycytidine, Dacogen, 5-aza-2'-deoxycytidine, 5-AZA-dC, 5-aza-CdR,NSC 127716) is a DNA methyltransferase inhibitor, incorporating into DNA and resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. It is used to treat myelodysplastic syndrome (MDS). Decitabine induces cell cycle arrest and apoptosis in various cancer cell lines.",228.21,"2353-33-5",45,197.19,10,43.82,"http://selleckchem.com/products/Decitabine.html","C8H12N4O4","free base","Deoxycytidine, Dacogen, 5-aza-2'-deoxycytidine, 5-AZA-dC, 5-aza-CdR,NSC 127716","NC1=NC(=O)N(C=N1)C2CC(O)C(CO)O2",-1.093,4,3,2]
["S1202","Dutasteride","e8","L1300-01","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","090095,200899,202204,202421,202530,202660,202808,203118,203241,204262,204292,204373,204376,204705,206373,206574,207935,208227,209909,202509,202975,207769","Endocrinology","5-alpha Reductase","Endocrinology & Hormones","Dutasteride (GI198745, GG-745) is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT).",528.53,"164656-23-9",62,117.31,"<1",0,"http://selleckchem.com/products/Dutasteride.html","C27H30F6N2O2","free base","GI198745, GG-745","CC12CCC3C(CCC4NC(=O)C=CC34C)C1CCC2C(=O)NC5=CC(=CC=C5C(F)(F)F)C(F)(F)F",5.703,2,2,4]
["S1204","Melatonin (NSC 113928)","f8","L1300-01","in 10mM DMSO","DMF,EMA,HMA,NDC","USP42-NF37;BP2019;Martindale:The Extra Pharmacopoeia",null,"Psychotic disorders","Apoptosis related,ATF/CREB & c-Fos/c-Jun,Autophagy,COX,Mitophagy,MT Receptor","GPCR & G Protein","Melatonin (NSC 113928, NSC 56423, N-Acetyl-5-methoxytryptamine,MT) is a MT receptor agonist, used as a dietary supplement. Melatonin is a selective ATF-6 inhibitor and downregulates COX-2. Melatonin enhances mitophagy and regulates the homeostasis of apoptosis and autophagy.",232.28,"73-31-4",47,202.34,"<1",0,"http://selleckchem.com/products/Melatonin.html","C13H16N2O2","free base","NSC 56423, N-Acetyl-5-methoxytryptamine,NSC 113928,MT","COC1=CC2=C([NH]C=C2CCNC(C)=O)C=C1",1.555,2,2,4]
["S1206","Bisoprolol fumarate","g8","L1300-01","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","075474,075643,075644,075831,077910,078635,204891,075469,075527,075579,075632,075642,075672,075686,075768,079106","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Bisoprolol fumarate (EMD33512) is a selective type β1 adrenergic receptor blocker.",441.52,"104344-23-2",88,199.31,88,199.31,"http://selleckchem.com/products/Bisoprolol-Fumarate.html","C22H35NO8","fumarate","EMD33512","CC(C)NCC(O)COC1=CC=C(COCCOC(C)C)C=C1.OC(=O)\\C=C\\C(O)=O",-0.635,5,2,14]
["S1207","Tivozanib (AV-951)","h8","L1300-01","in 10mM DMSO","EMA",null,null,"Cancer","c-Kit,PDGFR,VEGFR","Protein Tyrosine Kinase","Tivozanib (AV-951, KRN-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 30 nM/6.5 nM/15 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met, EGFR and IGF-1R. Phase 3.",454.86,"475108-18-0",20,43.97,"<1",0,"http://selleckchem.com/products/AV-951.html","C22H19ClN4O5","free base","KRN-951","COC1=CC2=C(C=C1OC)C(=CC=N2)OC3=CC=C(NC(=O)NC4=NOC(=C4)C)C(=C3)Cl",4.039,7,2,6]
["S1208","Doxorubicin (Adriamycin) HCl","a9","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","050467,050629,062921,062975,063097,063277,063336,064097,064140,065515,091418,091495,200146,200170,200901,203622,206062,208888,209825,203263,208657","Cancer","ADC Cytotoxin,AMPK,Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,HIV,Mitophagy,Topoisomerase","DNA Damage/DNA Repair","Doxorubicin (Adriamycin, NSC 123127, DOX, Hydroxydaunorubicin) HCl is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage, mitophagy and apoptosis in tumor cells. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.",579.98,"25316-40-9",100,172.42,20,34.48,"http://selleckchem.com/products/Adriamycin.html","C27H29NO11.HCl","Hydrochloride","NSC 123127, DOX, Doxorubicin hydrochloride, Hydroxydaunorubicin HCl,Adriamycin HCl","Cl.COC1=C2C(=O)C3=C(C(=C4CC(O)(CC(OC5CC(N)C(O)C(C)O5)C4=C3O)C(=O)CO)O)C(=O)C2=CC=C1",0.338,6,5,5]
["S1209","Fluorouracil (5-Fluorouracil, 5-FU)","b9","L1300-01","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.2;BP2019;KP Ⅹ;Ph.Int_6th;JP16;IP2010;Martindale:The Extra Pharmacopoeia","012209,040278,040279,040291,040333,040334,040379,040743,040772,040798,076526,077524,087791,087792,088766,088767,088929,089152,089368,089428,089434,089455,089508,089519,090368,091299,202668,202669,203122,203608,203609,210123,210124","Cancer","Apoptosis related,DNA/RNA Synthesis,HIV,Nucleoside Analog/Antimetabolite,Thymidylate Synthase","DNA Damage/DNA Repair","Fluorouracil (5-Fluorouracil, 5-FU, NSC 19893) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV.",130.08,"51-21-8",26,199.88,"<1",0,"http://selleckchem.com/products/Adrucil(Fluorouracil).html","C4H3FN2O2","free base","NSC 19893,5-Fluorouracil, 5-FU","FC1=CNC(=O)NC1=O",-1.102,2,2,0]
["S1210","Methotrexate (CL-14377)","c9","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","008085,011719,020079,040054,040233,040263,081099,081235,088648,088935,088936,088937,089158,089263,089293,089294,089295,089296,089308,089309,089322,089323,089341,089342,201749,207812,210040","Cancer/Hematology/Immunology/Inflammation","ADC Cytotoxin,DHFR","Metabolism","Methotrexate (CL14377, MTX, NCI-C04671, Amethopterin, WR19039, abitrexate), analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH. Methotrexate (MTX) induces apoptosis.",454.44,"59-05-2",90,198.05,"<1",0,"http://selleckchem.com/products/Abitrexate.html","C20H22N8O5","free base","NCI-C04671, Amethopterin, CL14377, WR19039, abitrexate","CN(CC1=NC2=C(N)N=C(N)N=C2N=C1)C3=CC=C(C=C3)C(=O)NC(CCC(O)=O)C(O)=O",0.114,7,3,9]
["S1212","Bendamustine (SDX105) HCl","d9","L1300-01","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","211530,204086,204104,204230,204771,205447,205476,205574,205752,205757,207149,209814,210410,210601","Cancer/Hematology","DNA/RNA Synthesis","DNA Damage/DNA Repair","Bendamustine (SDX-105, Cytostasane) HCl is a DNA-damaging agent with IC50 of 50 μM in cell-free assay.",394.72,"3543-75-7",78,197.61,2,5.07,"http://selleckchem.com/products/Bendamustine-Hydrochloride.html","C16H21Cl2N3O2.HCl","Hydrochloride","Cytostasane HCl","Cl.C[N]1C(=NC2=CC(=CC=C12)N(CCCl)CCCl)CCCC(O)=O",3.988,2,0,9]
["S1213","Nelarabine","e9","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","021877","Cancer/Hematology","DNA/RNA Synthesis","DNA Damage/DNA Repair","Nelarabine (506U78,Arranon) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.",297.27,"121032-29-9",60,201.84,3,10.09,"http://selleckchem.com/products/Arranon.html","C11H15N5O5","free base","506U78,Arranon","COC1=NC(=NC2=C1N=C[N]2C3OC(CO)C(O)C3O)N",-1.376,5,4,3]
["S1214","Bleomycin (NSC125066) sulfate","f9","L1300-01","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,BP2017,JP17","064084,065031,065033,065042,065185,065201,205030,209439","Cancer","Antineoplastic and Immunosuppressive Antibiotics,DNA/RNA Synthesis,Selection Antibiotics for Transfected Cell","DNA Damage/DNA Repair","Bleomycin Sulfate (Blenoxane,NSC125066) is a glycopeptide antibiotic and an anticancer agent for squamous cell carcinomas (SCC) with IC50 of 4 nM in UT-SCC-19A cells.",1512.62,"9041-93-4",100,66,0,0,"http://www.selleckchem.com/products/Bleomycin-sulfate.html","C55H85N17O25S4","Sulfate","Blenoxane,NSC125066","CC(O)C(NC(=O)C(C)C(O)C(C)NC(=O)C(NC(=O)C1=C(C)C(=NC(=N1)C(CC(N)=O)NCC(N)C(N)=O)N)C(OC2OC(CO)C(O)C(O)C2OC3OC(CO)C(O)C(OC(N)=O)C3O)C4=C[NH]C=N4)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C.O[S]([O-])(=O)=O",0,0,0,0]
["S1218","Clofarabine","g9","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","204029,205375,207831,208167,208857,208860,209775,210270,210283,212034","Cancer/Hematology","Apoptosis related,Autophagy,DNA/RNA Synthesis,RNR","DNA Damage/DNA Repair","Clofarabine (Clolar) inhibits the enzymatic activities of ribonucleotide reductase (RNR) (IC50 = 65 nM) and DNA polymerase. Clofarabine induces autophagy and apoptosis.",303.68,"123318-82-1",60,197.58,"<1",0,"http://selleckchem.com/products/Clofarabine.html","C10H11ClFN5O3","free base","Clolar","NC1=C2N=C[N](C3OC(CO)C(O)C3F)C2=NC(=N1)Cl",-0.085,4,3,2]
["S1221","Dacarbazine (NSC-45388)","h9","L1300-01","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,Ph.Int_6th,BP2017","070821,070822,070962,070990,071563,075259,075371,075812,075940","Cancer","Antineoplastic and Immunosuppressive Antibiotics,DNA/RNA Synthesis","DNA Damage/DNA Repair","Dacarbazine (NSC-45388, DTIC-Dome, Imidazole Carboxamide) is a triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis; used in the treatment of various cancers.",182.18,"4342-03-4",12,65.87,2,10.98,"http://selleckchem.com/products/Dacarbazine.html","C6H10N6O","free base","DTIC-Dome, Imidazole Carboxamide,NSC-45388","CN(C)N=NC1=C(N=C[NH]1)C(N)=O",-0.344,4,2,3]
["S1222","Dexrazoxane HCl (ICRF-187)","a10","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","076068,200752,207321","Cardiovascular Disease","Topoisomerase","DNA Damage/DNA Repair","Dexrazoxane HCl (ADR-529,Totect, ICRF-187, Zinecard, Cardioxane) is an intracellular iron chelator, which decreases the formation of superoxide radicals, used as a cardioprotective agent; also an inhibitor of topoisomerase II",304.73,"149003-01-0",60,196.9,60,196.9,"http://selleckchem.com/products/Dexrazoxane-Hydrochloride.html","C11H16N4O4.HCl","Hydrochloride","ADR-529,Totect, ICRF-187, Zinecard, Cardioxane","Cl.CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2",-1.722,4,2,3]
["S1223","Epirubicin (IMI 28) HCl","b10","L1300-01","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;Martindale:The Extra Pharmacopoeia","050807,065289,065331,065339,065343,065361,065371,065408,065411,065445,090075,090163,090266,091599","Cancer","Apoptosis related,Topoisomerase","DNA Damage/DNA Repair","Epirubicin HCl (Ellence, Pharmorubicin, Epirubicin Ebewe,IMI 28, NSC 256942, 4'-epidoxorubicin,Epirubicin hydrochloride), a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. Epirubicin induces apoptosis.",579.98,"56390-09-1",100,172.42,100,172.42,"http://selleckchem.com/products/Ellence.html","C27H29NO11.HCl","Hydrochloride","Ellence, Pharmorubicin, Epirubicin Ebewe,IMI 28, NSC 256942, 4'-epidoxorubicin,Epirubicin hydrochloride","Cl.COC1=C2C(=O)C3=C(C(=C4CC(O)(CC(OC5CC(N)C(O)C(C)O5)C4=C3O)C(=O)CO)O)C(=O)C2=CC=C1",0.338,6,5,5]
["S1225","Etoposide (VP-16)","c10","L1300-01","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.2;BP2019;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","074227,074228,074284,074290,074320,074351,074510,074513,074529,074813,074968,074983,075635,203507,204927","Cancer","Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,Autophagy,Mitophagy,Topoisomerase","DNA Damage/DNA Repair","Etoposide (VP-16213,Vepesid,VP-16) is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II  inhibition activity. Etoposide induces autophagy, mitophagy and apoptosis.",588.56,"33419-42-0",100,169.91,"<1",0,"http://selleckchem.com/products/Etopophos.html","C29H32O13","free base","VP-16213,Vepesid,VP-16","COC1=CC(=CC(=C1O)OC)C2C3C(COC3=O)C(OC4OC5COC(C)OC5C(O)C4O)C6=C2C=C7OCOC7=C6",0.935,10,3,5]
["S1227","Raloxifene HCl","d10","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","078193,090842,200825,204310,204491,206384,208206","Cancer/Metabolic Disease","Estrogen/progestogen Receptor","Endocrinology & Hormones","Raloxifene (LY156758, Keoxifene) HCl is a selective and orally active estrogen receptor modulator (SERM), which inhibits human cytosolic aldehyde oxidase-catalyzed phthalazine oxidation activity with IC50 of 5.7 nM.",510.04,"82640-04-8",100,196.06,"<1",0,"http://selleckchem.com/products/Evista.html","C28H27NO4S.HCl","Hydrochloride","LY156758 (Keoxifene) HCl","Cl.OC1=CC=C(C=C1)C2=C(C(=O)C3=CC=C(OCCN4CCCCC4)C=C3)C5=C(S2)C=C(O)C=C5",6.843,2,2,7]
["S1229","Fludarabine Phosphate","e10","L1300-01","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","022137,076349,076661,077790,078393,078544,078610,090724,200647,200648,203738","Cancer/Hematology","DNA/RNA Synthesis","DNA Damage/DNA Repair","Fludarabine Phosphate (F-ara-A, NSC 312887) is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis.",365.21,"75607-67-9",73,199.88,2,5.48,"http://selleckchem.com/products/Fludara.html","C10H13FN5O7P","Phosphate","F-ara-A (NSC 312887) Phosphate","NC1=NC(=NC2=C1N=C[N]2C3OC(CO[P](O)(O)=O)C(O)C3O)F",-1.384,5,3,4]
["S1231","Topotecan (NSC609699) HCl","f10","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","EP;USP;IP2010;Martindale:The Extra Pharmacopoeia","200199,022453,090620,091089,091199,091284,091376,091542,200582,201166,201191,202203,202351,204406,206074,206962","Cancer/Respiratory Disease","Apoptosis related,Autophagy,Topoisomerase","DNA Damage/DNA Repair","Topotecan HCl (Nogitecan HCl, SKFS 104864A,Hycamtin, NSC 609699) is a topoisomerase I inhibitor for MCF-7 Luc cells and DU-145 Luc cells with IC50 of 13 nM and 2 nM in cell-free assays, respectively. Topotecan HCl induces autophagy and apoptosis.",457.91,"119413-54-6",91,198.73,91,198.73,"http://selleckchem.com/products/Topotecan-Hydrochloride.html","C23H23N3O5.HCl","Hydrochloride","Nogitecan HCl, SKFS 104864A,Hycamtin, NSC 609699","Cl.CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC(=C(CN(C)C)C5=C4)O)C2=O",1.959,4,1,3]
["S1233","2-Methoxyestradiol (2-MeOE2)","g10","L1300-01","in 10mM DMSO","DMF",null,null,"Angiology/Cancer/Cardiovascular Disease","Apoptosis related,Autophagy,HIF,Microtubule Associated","Angiogenesis","2-Methoxyestradiol (2-MeOE2, NSC 659853, 2-ME2) depolymerizes microtubules and blocks HIF-1α nuclear accumulation and HIF-transcriptional activity. 2-Methoxyestradiol induces both autophagy and apoptosis in various carcinogenic cell lines.",302.41,"362-07-2",60,198.41,"<1",0,"http://selleckchem.com/products/2-Methoxyestradiol(2ME2).html","C19H26O3","free base","NSC 659853, 2-ME2","COC1=C(O)C=C2CCC3C(CCC4(C)C(O)CCC34)C2=C1",3.821,1,2,1]
["S1235","Letrozole (CGS 20267)","h10","L1300-01","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;KP Ⅹ;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","078190,090196,090289,090292,090405,090491,090789,090838,090934,091098,091191,091303,091466,091638,200161,201804,202048,202716,203796,205869,211717","Cancer","Aromatase,Autophagy","Endocrinology & Hormones","Letrozole (CGS 20267,Femara, Piroxicam) is a third generation inhibitor of aromatase with IC50 of 0.07-20 nM in cell-free assays.It has no effect on the plasma levels of 17α-OH progesterone, thyroid-stimulating hormone (TSH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), or androstenedione and does not affect normal urine electrolyte excretion or thyroid function in clinical studies. Letrozole induces autophagy.",285.3,"112809-51-5",57,199.79,"<1",0,"http://selleckchem.com/products/Letrozole.html","C17H11N5","free base","CGS 20267,Femara, Piroxicam","N#CC1=CC=C(C=C1)C([N]2C=NC=N2)C3=CC=C(C=C3)C#N",2.749,2,0,3]
["S1237","Temozolomide (CCRG 81045)","a11","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37 ;EP9.4;BP2019;IP2010;Martindale:The Extra Pharmacopoeia","078879,201528,201742,203490,203691,203898,203959,204159,204639,205227,206309,206413,206750,207658","Cancer","Apoptosis related,Autophagy,DNA/RNA Synthesis","DNA Damage/DNA Repair","Temozolomide (NSC 362856,TMZ,CCRG 81045,Methazolastone,Temodar,Temodal) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosis and exhibits antitumor activity.",194.15,"85622-93-1",38,195.72,"<1",0,"http://selleckchem.com/products/Methazolastone.html","C6H6N6O2","free base","NSC 362856,TMZ,CCRG 81045,Methazolastone,Temodar,Temodal","CN1N=NC2=C(N=C[N]2C1=O)C(N)=O",0.052,5,1,1]
["S1238","Tamoxifen (ICI 46474)","b11","L1300-01","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","070929,074504,074539,074732,075740,075797,076027,076179,076398,090878,206694","Cancer","Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,ATPase,Autophagy,Estrogen/progestogen Receptor,HSP (HSP90)","Angiogenesis","Tamoxifen (ICI 46474, (Z)-Tamoxifen, trans-Tamoxifen) is a selective estrogen receptor modulator (SERM). Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen induces apoptosis.",371.51,"10540-29-1",74,199.19,"<1",0,"http://selleckchem.com/products/Nolvadex.html","C26H29NO","Free Base","ICI 46474, (Z)-Tamoxifen, trans-Tamoxifen","CC/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(OCCN(C)C)C=C3.OC(=O)CC(O)(CC(O)=O)C(O)=O",1.966,4,0,13]
["S1241","Vincristine (NSC-67574) sulfate","c11","L1300-01","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","070411,070777,070778,070873,071222,071223,071559,071560,071561,071937,076296,076401","Cancer/Hematology/Respiratory Disease","Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,Autophagy,Microtubule Associated","Cytoskeletal Signaling","Vincristine sulfate (NSC-67574, Leurocristine, Oncovin, 22-Oxovincaleukoblastine) is an inhibitor of polymerization of microtubules by binding to tubulin with IC50 of 32 μM in a cell-free assay. Vincristine sulfate induces apoptosis.",923.04,"2068-78-2",100,108.34,60,65,"http://selleckchem.com/products/Vincristine-Sulfate.html","C46H58N4O14S","free base","Leurocristine, Oncovin, NSC-67574, 22-Oxovincaleukoblastine","CCC1(O)CC2CN(CCC3=C([NH]C4=C3C=CC=C4)C(C2)(C(=O)OC)C5=CC6=C(C=C5OC)N(C=O)C7C(O)(C(OC(C)=O)C8(CC)C=CCN9CCC67C89)C(=O)OC)C1.O[S](O)(=O)=O",3.365,8,1,10]
["S1243","Agomelatine (S20098)","d11","L1300-01","in 10mM DMSO","DMF,EMA,HMA,CFDA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","5-HT Receptor","Neuronal Signaling","Agomelatine (Valdoxan, Melitor, Thymanax,S20098) is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.",243.3,"138112-76-2",48,197.29,"<1",0,"http://selleckchem.com/products/Agomelatine.html","C15H17NO2","free base","Valdoxan, Melitor, Thymanax,S20098","COC1=CC2=C(CCNC(C)=O)C=CC=C2C=C1",2.17,2,1,4]
["S1245","Latrepirdine 2HCl","e11","L1300-01","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Others","5-HT Receptor,GluR,Histamine Receptor","Neuronal Signaling","Latrepirdine is an orally active,and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihistamine drug.",392.37,"97657-92-6",24,61.17,"<1",0,"http://selleckchem.com/products/Dimebon.html","C21H25N3.2HCl","Dihydrochloride","N/A","Cl.Cl.CN1CCC2=C(C1)C3=C(C=CC(=C3)C)[N]2CCC4=CC=C(C)N=C4",4.769,1,0,3]
["S1247","Leflunomide (HWA486)","f11","L1300-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","077083,077084,077085,077086,077087,077090,091369,212308","Inflammation","AhR,Dehydrogenase","Metabolism","Leflunomide (HWA486, RS-34821, SU101, Arava) is a pyrimidine synthesis and protein tyrosine kinase inhibitor belonging to the DMARD, used as an immunosuppressant agent. The active metabolite of Leflunomide is A77 1726, which inhibits dihydroorotate dehydrogenase (DHODH). Leflunomide is also an agonist of the AhR.",270.21,"75706-12-6",54,199.84,"<1",0,"http://selleckchem.com/products/Leflunomide.html","C12H9F3N2O2","free base","HWA486, RS-34821, SU101, Arava","CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F",2.156,3,1,3]
["S1250","Enzalutamide (MDV3100)","g11","L1300-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,203415,"Cancer","Androgen Receptor,Autophagy","Endocrinology & Hormones","Enzalutamide (MDV3100) is an androgen-receptor (AR) antagonist with IC50 of 36 nM in LNCaP cells. Enzalutamide is shown to increase autophagy.",464.44,"915087-33-1",92,198.09,"<1",0,"http://selleckchem.com/products/MDV3100.html","C21H16F4N4O2S","free base","MDV3100","CNC(=O)C1=C(F)C=C(C=C1)N2C(=S)N(C(=O)C2(C)C)C3=CC=C(C#N)C(=C3)C(F)(F)F",4.954,2,1,4]
["S1251","Dienogest","h11","L1300-01","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","202349,202999","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Dienogest (STS 557) is an orally active synthetic progesterone, used for contraception and the treatment of endometriosis.",311.42,"65928-58-7",62,199.09,"<1",0,"http://selleckchem.com/products/Dienogest.html","C20H25NO2","free base","STS 557","CC12CCC3=C4CCC(=O)C=C4CCC3C1CCC2(O)CC#N",3.046,1,0,1]
["S1252","Entecavir Hydrate","a2","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.7;BP2019;Martindale:The Extra Pharmacopoeia","202122,205740,205824,206217,206226,206294,206652,206672,206745,206872,208721,208782","Infection/Inflammation","Reverse Transcriptase","Microbiology","Entecavir Hydrate (ETV, Baraclude,BMS200475 Hydrate,SQ34676 Hydrate), a new deoxyguanine nucleoside analogue, is a selective inhibitor of the replication of the hepatitis B virus (HBV).",295.29,"209216-23-9",59,199.8,"<1",0,"https://www.selleckchem.com/products/s1252-entecavir.html","C12H15N5O3.H2O","Hydrate","ETV, Baraclude,BMS200475 Hydrate,SQ34676 Hydrate","O.NC1=NC(=O)C2=C(N1)[N](C=N2)C3CC(O)C(CO)C3=C",-1.611,3,4,2]
["S1255","Nepafenac","b2","L1300-02","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","203491,021862","Inflammation","COX","Neuronal Signaling","Nepafenac (AHR 9434, AL 6515) is a prodrug of amfenac that acts as an inhibitor of COX-1 and COX-2 activity, used in the treatment of pain and inflammation associated with cataract surgery.",254.28,"78281-72-8",50,196.63,"<1",0,"http://selleckchem.com/products/Nepafenac.html","C15H14N2O2","free base","AHR 9434, AL 6515","NC(=O)CC1=CC=CC(=C1N)C(=O)C2=CC=CC=C2",1.524,2,2,4]
["S1256","Rufinamide","c2","L1300-02","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","204988,205075,205095,207363,211388","Neurological Disease","Sodium Channel","Transmembrane Transporters","Rufinamide (CGP 33101,E 2080,RUF 331,Banzel) is a voltage-gated sodium channel blocker, used an anticonvulsant medication.",238.19,"106308-44-5",18,75.57,"<1",0,"http://selleckchem.com/products/Rufinamide.html","C10H8F2N4O","free base","CGP 33101,E 2080,RUF 331,Banzel","NC(=O)C1=C[N](CC2=C(F)C=CC=C2F)N=N1",1.437,3,1,3]
["S1257","Posaconazole (SCH 56592)","d2","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","Martindale:The Extra Pharmacopoeia","208768,209983,211500","Infection","P450 (e.g. CYP17)","Metabolism","Posaconazole (SCH 56592,POS,Noxafil) is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14ɑ demethylase inhibitor with IC50 of 0.25 μM. Posaconazole has a median terminal elimination half-life of 15-35 hours.",700.78,"171228-49-2",100,142.7,"<1",0,"http://selleckchem.com/products/Posaconazole.html","C37H42F2N8O4","free base","SCH 56592,POS,Noxafil","CCC(C(C)O)N1N=CN(C1=O)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(OCC5COC(C5)(C[N]6C=NC=N6)C7=CC=C(F)C=C7F)C=C4",5.096,6,1,12]
["S1258","Prasugrel","e2","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","205790,205888,205897,205913,205927,205987,206021","Cardiovascular Disease","P2 Receptor","Neuronal Signaling","Prasugrel (Effient, Efient, Prasita,CS-747, LY640315,PCR 4099) is a thienopyridine ADP receptor (P2Y12) antagonist, used for the reduction of thrombotic cardiovascular events.",373.44,"150322-43-3",30,80.33,"<1",0,"http://selleckchem.com/products/Prasugrel.html","C20H20FNO3S","Free Base","Effient, Efient, Prasita,CS-747, LY640315,PCR 4099","CC(=O)OC1=CC2=C(CCN(C2)C(C(=O)C3CC3)C4=CC=CC=C4F)S1",3.801,3,0,6]
["S1259","Ramelteon","f2","L1300-02","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia","091610,091693","Neurological Disease","MT Receptor","GPCR & G Protein","Ramelteon (TAK-375) is a novel melatonin receptor agonist for human MT1 and MT2 receptors and chick forebrain melatonin receptors with Ki of 14 pM, 112 pM and 23.1 pM, respectively.",259.34,"196597-26-9",52,200.51,"<1",0,"http://selleckchem.com/products/Ramelteon.html","C16H21NO2","free base","TAK-375","CCC(=O)NCCC1CCC2=CC=C3OCCC3=C12",2.826,2,1,4]
["S1260","Cinacalcet (AMG-073) HCl","g2","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP;Martindale:The Extra Pharmacopoeia","090476,090539,203422,204377,206125,207008,208915,208971,209226,210207,210570","Endocrinology","CaSR","GPCR & G Protein","Cinacalcet (Mimpara, Sensipar,AMG-073) HCl represents a new class of compounds for the treatment of hyperparathyroidism.",393.87,"364782-34-3",79,200.57,"<1",0,"http://selleckchem.com/products/Cinacalcet-hydrochloride.html","C22H22F3N.HCl","Hydrochloride","Mimpara, Sensipar,AMG-073","Cl.CC(NCCCC1=CC(=CC=C1)C(F)(F)F)C2=CC=CC3=C2C=CC=C3",6.338,0,1,7]
["S1261","Celecoxib (SC 58635)","h2","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","076898,078857,200562,202240,204197,204519,204590,204776,206827,207061,207446,207677,208833,210071","Inflammation","COX","Neuronal Signaling","Celecoxib (Celebrex, Celebra,SC 58635) is a selective COX-2 inhibitor with IC50 of 40 nM in Sf9 cells.",381.37,"169590-42-5",76,199.28,"<1",0,"http://selleckchem.com/products/Celecoxib.html","C17H14F3N3O2S","free base","Celebrex, Celebra,SC 58635","CC1=CC=C(C=C1)C2=CC(=N[N]2C3=CC=C(C=C3)[S](N)(=O)=O)C(F)(F)F",4.428,3,1,4]
["S1267","Vemurafenib (PLX4032)","a3","L1300-02","in 10mM DMSO","FDA,EMA,NDC,PMDA",null,"202429","Cancer","Autophagy,Raf","MAPK","Vemurafenib (PLX4032, RG7204, RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay. 10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold. Vemurafenib (PLX4032, RG7204) induces autophagy.",489.92,"918504-65-1",97,197.99,"<1",0,"http://selleckchem.com/products/PLX-4032.html","C23H18ClF2N3O3S","free base","RG7204, RO5185426,PLX4032","CCC[S](=O)(=O)NC1=CC=C(F)C(=C1F)C(=O)C2=C[NH]C3=NC=C(C=C23)C4=CC=C(Cl)C=C4",4.953,4,2,7]
["S1271","Acarbose","b3","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","077532,078441,078470,090912,091053,091343,202271","Endocrinology/Metabolic Disease","Carbohydrate Metabolism","Metabolism","Acarbose(BAY g 5421,Prandase, Precose, Glucobay, Bay-g 5421) is an inhibitor of intestinal alpha-glucosidase, used to treat type 2 diabetes mellitus.",645.6,"56180-94-0",100,154.89,100,154.89,"http://selleckchem.com/products/Acarbose.html","C25H43NO18","free base","BAY g 5421,Prandase, Precose, Glucobay, Bay-g 5421","CC1OC(OC2C(O)C(O)C(OC2CO)OC3C(O)C(O)C(O)OC3CO)C(O)C(O)C1NC4C=C(CO)C(O)C(O)C4O",-6.839,5,13,9]
["S1276","Adapalene","c3","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","090824,090962,091314,200298,201000,203981,204593,208322,203790,205033,206164,206959,208108,209148,209641","Inflammation","Retinoid Receptor","Metabolism","Adapalene (CD-271) is a dual RAR and RXR agonist, used in the treatment of acne.",412.52,"106685-40-9",8,19.39,"<1",0,"http://selleckchem.com/products/Adapalene.html","C28H28O3","free base","CD-271","COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(O)=O)[C]45CC6[CH2][CH](C[CH]([CH2]6)C4)C5",6.279,2,0,4]
["S1278","Altretamine","d3","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","019926","Cancer","DNA alkylator","DNA Damage/DNA Repair","Altretamine (Hexamethylmelamine, NSC13875, ENT50852) is an anti-neoplastic agent.",210.28,"645-05-6",15,71.33,"<1",0,"http://selleckchem.com/products/Altretamine.html","C9H18N6","free base","Hexamethylmelamine, NSC13875, ENT50852","CN(C)C1=NC(=NC(=N1)N(C)C)N(C)C",1.995,3,0,3]
["S1280","Amisulpride","e3","L1300-02","in 10mM DMSO","DMF,CFDA,HMA","BP2019;EP9.6;Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Dopamine Receptor","Neuronal Signaling","Amisulpride (DAN-2163) is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.",369.48,"71675-85-9",73,197.57,"<1",0,"http://selleckchem.com/products/Amisulpride.html","C17H27N3O4S","free base","DAN-2163","CCN1CCCC1CNC(=O)C2=CC(=C(N)C=C2OC)[S](=O)(=O)CC",1.127,4,2,7]
["S1281","Aniracetam","f3","L1300-02","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","AMPA Receptor-kainate Receptor-NMDA Receptor","Neuronal Signaling","Aniracetam (RO 13-5057) is a nootropics and neuroprotective drug.",219.24,"72432-10-1",44,200.69,"<1",0,"http://selleckchem.com/products/Aniracetam.html","C12H13NO3","free base","RO 13-5057","COC1=CC=C(C=C1)C(=O)N2CCCC2=O",1.267,3,0,2]
["S1282","Artemisinin","g3","L1300-02","in 10mM DMSO","CFDA","Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","ADC Cytotoxin,Anti-infection","Microbiology","Artemisinin (Qinghaosu,Artemisinine,Coartem,NSC 369397) is a sesquiterpene endoperoxide which is a potent antimalarial agent.",282.33,"63968-64-9",57,201.89,"<1",0,"http://selleckchem.com/products/Artemisinin.html","C15H22O5","free base","Qinghaosu,Artemisinine,Coartem,NSC 369397","CC1CCC2C(C)C(=O)OC3OC4(C)CCC1C23OO4",1.998,5,0,0]
["S1283","Asenapine maleate","h3","L1300-02","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"206107,022117","Neurological Disease","5-HT Receptor,Adrenergic Receptor","Neuronal Signaling","Asenapine maleate (Org 5222) is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder.",401.84,"85650-56-2",80,199.08,"<1",0,"http://selleckchem.com/products/Asenapine.html","C17H16ClNO.C4H4O4","Maleate","Org 5222","CN1CC2C(C1)C3=C(OC4=C2C=CC=C4)C=CC(=C3)Cl.OC(=O)\\C=C/C(O)=O",0.883,3,0,2]
["S1284","Benazepril HCl","a4","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","077179,077183,077215,077375,077890,078381,078466,079047,090149,090364,091431,202239,078466,078652,021714,076118,076211,076267,076333,076344,076402,076430,076476,076820,077128,078212,078848,076342,076348,076612,076631,076688,077483,078794","Cardiovascular Disease/Endocrinology/Metabolic Disease","RAAS","Endocrinology & Hormones","Benazepril HCl (CGS 14824A) is a novel angiotensin I converting enzyme inhibitor, used primarily in treatment of hypertension.",460.95,"86541-74-4",92,199.59,19,41.22,"http://selleckchem.com/products/Benazepril-hydrochloride.html","C24H28N2O5.HCl","Hydrochloride","CGS 14824A HCl","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC2CCC3=C(C=CC=C3)N(CC(O)=O)C2=O",1.003,4,1,10]
["S1286","Budesonide","b4","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","077519,078202,078404,078949,078949,090379,090410,201966,204548,205457,205710,206134,206200,206623,206724,207367,209041,210897,211929","Immunology/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Budesonide(Labazenit) is a glucocorticoid steroid for the treatment of asthma, non-infectious rhinitis.",430.53,"51333-22-3",86,199.75,"<1",0,"http://selleckchem.com/products/Budesonide.html","C25H34O6","free base","Labazenit","CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC3(C)C2(O1)C(=O)CO",2.198,4,2,4]
["S1287","Bumetanide","c4","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010","074160,074225,074332,074441,074613,074700,079196,202900,209724,209916","Cardiovascular Disease","NKCC","Transmembrane Transporters","Bumetanide (Bumex) is a loop diuretic of the sulfamyl category to treat heart failure. Bumetanide is a selective Na+-K+-Cl- cotransporter 1 (NKCC1) inhibitor, weakly inhibits NKCC2, with IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively.",364.42,"28395-03-1",73,200.32,"<1",0,"http://selleckchem.com/products/Bumetanide.html","C17H20N2O5S","free base","N/A","CCCCNC1=C(OC2=CC=CC=C2)C(=CC(=C1)C(O)=O)[S](N)(=O)=O",2.862,4,2,8]
["S1289","Carmofur","d4","L1300-02","in 10mM DMSO","CFDA","KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia",null,"Cancer","COVID-19,DNA/RNA Synthesis","DNA Damage/DNA Repair","Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.",257.26,"61422-45-5",52,202.13,"<1",0,"http://selleckchem.com/products/Carmofur.html","C11H16FN3O3","free base","HCFU","CCCCCCNC(=O)N1C=C(F)C(=O)NC1=O",1.125,3,2,5]
["S1291","Cetirizine DiHCl","e4","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","076601,077279,077472,078398,078412,078488,078496,078617,078757,078870,078876,090191,090751,090766","Immunology/Inflammation","Histamine Receptor","Neuronal Signaling","Cetirizine DiHCl (Zyrtec, Reactine,UCB P071) is an antihistamine.",461.81,"83881-52-1",92,199.22,92,199.22,"http://selleckchem.com/products/Cetirizine-Dihydrochloride.html","C21H25ClN2O3.2HCl","Dihydrochloride","Zyrtec, Reactine,UCB P071","Cl.Cl.OC(=O)COCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3",1.217,2,0,8]
["S1293","Cilnidipine (FRC-8653)","f4","L1300-02","in 10mM DMSO","DMF,CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Cilnidipine (FRC-8653) is a unique L-type and N-type calcium channel blocker, used for high blood pressure treatment.",492.52,"132203-70-4",99,201.01,"<1",0,"http://selleckchem.com/products/Cilnidipine.html","C27H28N2O7","free base","FRC-8653","COCCOC(=O)C1=C(C)NC(=C(C1C2=CC(=CC=C2)[N+]([O-])=O)C(=O)OC\\C=C\\C3=CC=CC=C3)C",3.686,5,1,12]
["S1294","Cilostazol (OPC-13013)","g4","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","077019,077020,077021,077022,077024,077027,077028,077030,077150,077208,077310,077323,077708,077722,077831,077898","Cardiovascular Disease","PDE","Metabolism","Cilostazol (Pletal,OPC-13013) is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 μM and inhibitor of adenosine uptake.",369.46,"73963-72-1",74,200.29,"<1",0,"http://selleckchem.com/products/Cilostazol.html","C20H27N5O2","free base","Pletal,OPC-13013","O=C1CCC2=C(N1)C=CC(=C2)OCCCCC3=NN=N[N]3C4CCCCC4",3.23,5,1,7]
["S1299","Floxuridine (NSC 27640)","h4","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","071055,075387,075837,203008","Cancer","Apoptosis related,CMV,DNA/RNA Synthesis","DNA Damage/DNA Repair","Floxuridine (NSC 27640, Deoxyfluorouridine, FUDR) is a prodrug that is rapidly catabolized to 5-fluorouracil in vivo. Floxuridine is used to treat various cancers, particularly metastases to the liver. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage and apoptosis. Floxuridine has antiviral effects against HSV and CMV.",246.19,"50-91-9",49,199.03,49,199.03,"http://selleckchem.com/products/Floxuridine.html","C9H11FN2O5","free base","Deoxyfluorouridine, FUDR,NSC 27640","OCC1OC(CC1O)N2C=C(F)C(=O)NC2=O",-1.775,3,3,2]
["S1300","Tegafur (FT-207)","a5","L1300-02","in 10mM DMSO","DMF,EMA,HMA,CFDA,PMDA","KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia",null,"Cancer","DNA/RNA Synthesis","DNA Damage/DNA Repair","Tegafur (NSC 148958,Fluorafur,FT-207) is a substance being used in the treatment of some types of cancer.",200.17,"17902-23-7",40,199.83,8,39.97,"http://selleckchem.com/products/Ftorafur.html","C8H9FN2O3","free base","NSC 148958,Fluorafur,FT-207","FC1=CN(C2CCCO2)C(=O)NC1=O",-0.625,3,1,1]
["S1302","Ifosfamide (NSC109724)","b5","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","076078,076619,076657,090181,201689","Cancer","DNA alkylator,DNA/RNA Synthesis","DNA Damage/DNA Repair","Ifosfamide (Mitoxana, Ifex,Isophosphamide,NSC109724) is a nitrogen mustard alkylating agent used in the treatment of cancer.",261.09,"3778-73-2",52,199.17,52,199.17,"http://selleckchem.com/products/Ifosfamide.html","C7H15Cl2N2O2P","free base","Mitoxana, Ifex,Isophosphamide,NSC109724","ClCCN[P]1(=O)OCCCN1CCCl",0.144,2,1,5]
["S1304","Megestrol Acetate","c5","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","070646,070647,072422,072423,074458,074621,074745,075671,075681,075997,076721,077404,203139,203960,204688","Cancer/Endocrinology","Androgen Receptor,Estrogen/progestogen Receptor","Endocrinology & Hormones","Megestrol acetate (BDH1298, SC10363) is a synthetic progestogen, used to treat breast cancer and loss of appetite.",384.51,"595-33-5",33,85.82,"<1",0,"http://selleckchem.com/products/Megestrol-Acetate.html","C24H32O4","free base","BDH1298, SC10363","CC(=O)OC1(CCC2C3C=C(C)C4=CC(=O)CCC4(C)C3CCC12C)C(C)=O",3.505,4,0,3]
["S1305","Mercaptopurine (6-MP)","d5","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","040461,040528,040594","Cancer/Immunology","DNA/RNA Synthesis","DNA Damage/DNA Repair","Mercaptopurine(6-MP) is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.",152.18,"50-44-2",30,197.13,"<1",0,"http://selleckchem.com/products/Mercaptopurine.html","C5H4N4S","free base","6-MP","S=C1N=CNC2=C1[NH]C=N2",0.367,2,2,0]
["S1319","Costunolide","e5","L1300-02","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Telomerase","DNA Damage/DNA Repair","Costunolide (NSC 106404), a natural sesquiterpene compound with multiple biological activities; inhibits FPTase with IC50 of 20 μM, also inhibits telomerase with IC50 of 65-90 μM.",232.32,"553-21-9",47,202.31,"<1",0,"http://selleckchem.com/products/Costunolide.html","C15H20O2","free base","NSC 106404","CC/1=C\\CC\\C(=C\\C2OC(=O)C(=C)C2CC1)C",4.022,2,0,0]
["S1322","Dexamethasone (MK-125)","f5","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP39-NF34;BP2015;JP16;IP2010","040700,080399,080968,083420,083806,084013,084081,084084,084086,084327,084457,084610,084611,084612,084613,084614,084754,084763,084764,084765,084766,085376,085455,085456,085458,085818,085840,087533,087534,087916,088149,088237,088248,088254,088306,088316,088448,088469,088481,088997,089170,090891,091188,201270","Immunology/Inflammation/Infection/Respiratory Disease","Autophagy,Complement System,COVID-19,Glucocorticoid Receptor,IL Receptor,Mitophagy","Immunology & Inflammation","Dexamethasone (MK-125, NSC 34521, Hexadecadrol, Prednisolone F) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects. Dexamethasone induces autophagy and mitophagy. Dexamethasone is tested in hospitalized patients with COVID-19 and is found to have benefits for critically ill patients.",392.46,"50-02-2",79,201.29,"<1",0,"http://selleckchem.com/products/Dexamethasone.html","C22H29FO5","free base","NSC 34521, Hexadecadrol, Prednisolone F,MK-125","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO",1.708,2,2,2]
["S1324","Doxazosin Mesylate","g5","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.8;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","075353,075426,075432,075453,075466,075509,075536,075574,075580,075609,075646,075750,076161,202824,205210,208719,209013","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Doxazosin, a quinazoline-derivative, selectively antagonizes postsynaptic α1-adrenergic receptors, used in the treatment of high blood pressure and urinary retention associated with benign prostatic hyperplasia.",547.58,"77883-43-3",15,27.39,"<1",0,"http://selleckchem.com/products/Doxazosin-mesylate.html","C23H25N5O5.CH4O3S","Mesylate","N/A","COC1=C(OC)C=C2C(=NC(=NC2=C1)N3CCN(CC3)C(=O)C4COC5=C(O4)C=CC=C5)N.C[S](O)(=O)=O",2.071,7,1,4]
["S1326","Edaravone","h5","L1300-02","in 10mM DMSO","FDA,CFDA,NDC,PMDA","JP17;Martindale:The Extra Pharmacopoeia","209176","Cardiovascular Disease","Antioxidant","ER stress & UPR","Edaravone (MCI-186) is a novel potent free radical scavenger that has been clinically used to reduce the neuronal damage following ischemic stroke.",174.2,"89-25-8",35,200.92,"<1",0,"http://selleckchem.com/products/Edaravone.html","C10H10N2O","free base","MCI-186","CC1=NN(C(=O)C1)C2=CC=CC=C2",1.123,2,0,1]
["S1328","Etodolac","a6","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","074819,074839,074840,074841,074842,074844,074846,074847,074883,074892,074899,074903,074927,074929,074932,074942,075009,075012,075069,075071,075074,075078,075104,075126,075226,075419,075665,075696,075829,075943,076004,076174,091134,208834,209888","Inflammation","COX","Neuronal Signaling","Etodolac(AY-24236) is a nonsteroidal anti-inflammatory drug (NSAID) and a COX inhibitor, used for the treatment of inflammation and pain.",287.35,"41340-25-4",58,201.84,"<1",0,"http://selleckchem.com/products/Etodolac.html","C17H21NO3","free base","AY-24236","CCC1=CC=CC2=C1[NH]C3=C2CCOC3(CC)CC(O)=O",3.723,2,1,4]
["S1330","Felbamate","b6","L1300-02","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","201680,202284,202385,204595,206314,207093,208970","Neurological Disease","NMDAR","Neuronal Signaling","Felbamate (Felbatol, ADD-03055,W-554) is an anticonvulsant drug used in the treatment of epilepsy; NMDAR antagonist.",238.24,"25451-15-4",48,201.48,"<1",0,"http://selleckchem.com/products/Felbamate.html","C11H14N2O4","free base","Felbatol, ADD-03055,W-554","NC(=O)OCC(COC(N)=O)C1=CC=CC=C1",0.984,4,2,7]
["S1331","Fluconazole (UK 49858)","c6","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","074681,076042,076077,076086,076213,076246,076332,076351,076386,076424,076432,076507,076658,076665,076918,076957,077253,077523,077731,078423,079150,208963","Infection","Fungal,P450 (e.g. CYP17)","Metabolism","Fluconazole (Diflucan, Trican, Alfumet,UK 49858) is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol,used in the treatment and prevention of superficial and systemic fungal infections.",306.27,"86386-73-4",61,199.17,"<1",0,"http://selleckchem.com/products/Fluconazole.html","C13H12F2N6O","free base","Diflucan, Trican, Alfumet,UK 49858","OC(C[N]1C=NC=N1)(C[N]2C=NC=N2)C3=C(F)C=C(F)C=C3",0.75,4,0,5]
["S1332","Flumazenil (RO 15-1788)","d6","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","076256,076589,076755,076787,076955,077071,078527,078595,090584","Neurological Disease","GABA Receptor","Neuronal Signaling","Flumazenil (RO 15-1788) is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses.",303.29,"78755-81-4",5,16.49,"<1",0,"http://selleckchem.com/products/Flumazenil.html","C15H14FN3O3","free base","RO 15-1788","CCOC(=O)C1=C2CN(C)C(=O)C3=CC(=CC=C3[N]2C=N1)F",1.583,4,0,3]
["S1333","Fluoxetine (Lilly 110140) HCl","e6","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","075662,075787,074803,075049,075207,075245,075292,075452,075464,075465,075506,075514,075525,075577,075658,075690,075755,075807,075810,075865,075872,075920,076001,076006,076015,076022,076024,076165,076237,076251,076287,076458,076922,076990,077469,077849,078045,078143,078572,078619,079209,090223,201336,202133,203836,204597,206937,206993,208698,209419,209695,210935,211051,211282,211477,211632,211653,211696,211721","Neurological Disease","5-HT Receptor","Neuronal Signaling","Fluoxetine HCl (Prozac, Sarafem,LY-110140) is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, used in the treatment of depression.",345.79,"56296-78-7",69,199.54,4,11.57,"http://selleckchem.com/products/Fluoxetine-hydrochloride.html","C17H18F3NO.HCl","Hydrochloride","Prozac, Sarafem,LY-110140","Cl.CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C2=CC=CC=C2",4.415,1,1,7]
["S1334","Flupirtine maleate","f6","L1300-02","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","DNA/RNA Synthesis","DNA Damage/DNA Repair","Flupirtine maleate is the salt form of Flupirtine, which is a centrally acting non-opioid analgesia, is a selective neuronal potassium channel opener that also has NMDA receptor antagonist properties.",420.39,"75507-68-5",84,199.81,"<1",0,"http://selleckchem.com/products/Flupirtine-maleate.html","C15H17FN4O2.C4H4O4","Maleate","N/A","CCOC(=O)NC1=C(N)N=C(NCC2=CC=C(F)C=C2)C=C1.OC(=O)\\C=C\\C(O)=O",2.76,5,3,8]
["S1336","Fluvoxamine (DU-23000) maleate","g6","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","075887,075888,075889,075893,075894,075897,075898,075899,075900,075901,075902,075950,076125,091476,091482,203240","Neurological Disease","Serotonin Transporter","Neuronal Signaling","Fluvoxamine maleate (DU-23000, MK-264) is a selective serotonin (5-HT) reuptake inhibitor (SSRI), used in the treatment of obsessive-compulsive disorder.",434.41,"61718-82-9",87,200.27,"<1",0,"http://selleckchem.com/products/Fluvoxamine-maleate.html","C19H25F3N2O6","Maleate","MK-264,DU-23000 maleate","COCCCCC(=N\\OCCN)/C1=CC=C(C=C1)C(F)(F)F.OC(=O)\\C=C/C(O)=O",0.111,5,1,12]
["S1340","Gatifloxacin","h6","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP;IP2010;Martindale:The Extra Pharmacopoeia","079084,202653,203189,203190,204227,206446","Infection","Topoisomerase","DNA Damage/DNA Repair","Gatifloxacin (AM-1155, CG5501, BMS-206584) is an antibiotic of the fourth-generation fluoroquinolone family, and inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.",375.39,"112811-59-3",7,18.65,"<1",0,"http://selleckchem.com/products/Gatifloxacin.html","C19H22FN3O4","free base","AM-1155, CG5501, BMS-206584","COC1=C2N(C=C(C(O)=O)C(=O)C2=CC(=C1N3CCNC(C)C3)F)C4CC4",-0.909,3,1,4]
["S1342","Genistein (NPI 031L)","a7","L1300-02","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Cancer/Cardiovascular Disease/Infection","EGFR,Topoisomerase","Protein Tyrosine Kinase","Genistein (NPI 031L), a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK)  which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM.",270.24,"446-72-0",54,199.82,"<1",0,"http://selleckchem.com/products/Genistein.html","C15H10O5","free base","NPI 031L","OC1=CC=C(C=C1)C2=COC3=C(C(=CC(=C3)O)O)C2=O",2.14,2,3,1]
["S1344","Glimepiride","b7","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","076802,076875,076995,077091,077274,077280,077295,077366,077370,077486,077624,077911,078181,078952,091220,202112,202759","Endocrinology/Metabolic Disease","Potassium Channel","Transmembrane Transporters","Glimepiride(HOE-490) is a potent Kir6.2/SUR inhibitor with IC50 of 3.0 nM, 5.4 nM, and 7.3 nM for SUR1, SUR2A and SUR2B, used in the treatment of type 2 diabetes mellitus.",490.62,"93479-97-1",11,22.42,"<1",0,"http://selleckchem.com/products/Glimepiride.html","C24H34N4O5S","free base","HOE-490","CCC1=C(C)CN(C(=O)NCCC2=CC=C(C=C2)[S](=O)(=O)NC(=O)NC3CCC(C)CC3)C1=O",3.781,5,3,7]
["S1351","Ivermectin (MK-933)","c7","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","204154,210019,210720","Infection","AChR,Autophagy,Chloride Channel,COVID-19,HIV,Mitophagy,P2 Receptor","Transmembrane Transporters","Ivermectin (MK-933, IVM) is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug. Ivermectin (MK-933, IVM) is a specific positive allosteric effector of P2X4 and α7 nicotinic acetylcholine receptors (nAChRs). Ivermectin has potent antiviral activity towards both HIV-1 and dengue virus. Ivermectin induces autophagy through the AKT/mTOR signaling pathway and mitophagy.",875.09,"70288-86-7",100,114.27,"<1",0,"http://selleckchem.com/products/Ivermectin.html","C48H74O14","Free Base","MK-933","CCC(C)C1OC2(CCC1C)CC3CC(C\\C=C(C)\\C(OC4CC(OC)C(OC5CC(OC)C(O)C(C)O5)C(C)O4)C(C)\\C=C\\C=C\\6COC7C(O)C(=CC(C(=O)O3)C67O)C)O2",4.743,11,2,8]
["S1354","Lansoprazole","d7","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.3;BP2019;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","077255,078730,090331,090763,091212,091269,091509,200816,201921,202176,202194,202319,202366,202396,202637,202727,203187,203203,203306,203957,203964,205868,207156,207157,207394,208025,208784,200218,202588,206006","Gastrointestinal Disease","ATPase,Proton Pump","Transmembrane Transporters","Lansoprazole (A-65006, AG-1749) is a proton-pump inhibitor (PPI) that binds covalently to parietal cell H(+),K(+)-ATPase. Lansoprazole prevents the stomach from producing gastric acid.",369.36,"103577-45-3",74,200.35,"<1",0,"http://selleckchem.com/products/Lansoprazole.html","C16H14F3N3O2S","free base","A-65006, AG-1749","CC1=C(OCC(F)(F)F)C=CN=C1C[S](=O)C2=NC3=CC=CC=C3[NH]2",3.442,4,1,6]
["S1356","Levetiracetam (UCB-L059)","e7","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.4;BP2019;Martindale:The Extra Pharmacopoeia","076919,076920,077319,077324,077408,078042,078101,078106,078154,078234,078526,078582,078731,078774,078797,078858,078869,078904,078918,078960,078976,078993,079042,079063,079107,079120,090025,090028,090079,090187,090261,090263,090461,090484,090511,090515,090601,090754,090767,090813,090843,090876,090893,090981,090992,091093,091261,091285,091291,091338,091360,091399,091430,091485,091491,091557,091627,091668,200475,201157,201293,201464,202095,202143,202167,202524,202533,202869,202958,203052,203059,203067,203308,203468,204312,204511,204754,205102,205102,206838,207175,209781,209934","Neurological Disease","AChR,Calcium Channel","Transmembrane Transporters","Levetiracetam (UCB-L059, SIB-S1) is an anticonvulsant medication used to treat epilepsy. Levetiracetam (UCB-L059, SIB-S1) is an agonist of muscarinic acetylcholine receptors (mAChR). Levetiracetam modulates the presynaptic P/Q-type voltage-dependent calcium (Ca2+) channel.",170.21,"102767-28-2",34,199.75,34,199.75,"http://selleckchem.com/products/Levetiracetam.html","C8H14N2O2","free base","UCB-L059, SIB-S1","CCC(N1CCCC1=O)C(N)=O",-0.304,2,1,3]
["S1357","Lidocaine","f7","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Ph.Int_6th;JP17;BP2017;USP40-NF35;IP2010;Martindale:The Extra Pharmacopoeia","040911,080198,080210,086724,200675,202346,205318,206297,206498,207810,208604,208822,210256,210958,211019,211469","Neurological Disease","Histamine Receptor","Neuronal Signaling","Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.",234.34,"137-58-6",47,200.56,9,38.41,"http://selleckchem.com/products/Lidocaine.html","C14H22N2O","Free Base","Alphacaine","CCN(CC)CC(=O)NC1=C(C)C=CC=C1C",2.626,1,1,5]
["S1358","Loratadine (SCH29851)","g7","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","021512,021734,075209,075505,075565,075728,075790,075815,075822,075990,076011,076134,076154,076301,076471,076529,076805,077421,078447,201865,202538,206214,207569,208314,208477,208931,210088","Immunology","Histamine Receptor","Neuronal Signaling","Loratadine (Alavert,Claritin,SCH29851) is a histamine H1 receptor antagonist, used to treat allergies. Also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.",382.88,"79794-75-5",17,44.4,"<1",0,"http://selleckchem.com/products/Loratadine.html","C22H23ClN2O2","free base","Alavert,Claritin,SCH29851","CCOC(=O)N1CCC(CC1)=C2C3=C(CCC4=C2N=CC=C4)C=C(Cl)C=C3",5,3,0,2]
["S1359","Losartan Potassium (DuP 753)","h7","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","076958,077424,077459,078232,078243,090083,090382,090428,090467,090544,090790,091129,091497,091541,091590,200290,201170,202230,203030,203835,204795","Cardiovascular Disease/Endocrinology/Metabolic Disease","Angiotensin Receptor","GPCR & G Protein","Losartan Potassium (DuP 753, MK 954) is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.",462.01,"124750-99-8",92,199.13,92,199.13,"http://selleckchem.com/products/losartan-potassium.html","C22H23ClKN6O","Potassium salt","MK 954,DuP 753","[KH].CCCCC1=NC(=C(CO)[N]1CC2=CC=C(C=C2)C3=C(C=CC=C3)C4=NN=N[NH]4)Cl",4.241,4,2,8]
["S1367","Amonafide","a8","L1300-02","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Cancer","Topoisomerase","DNA Damage/DNA Repair","Amonafide (NSC308847, AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage. Phase 3.",283.33,"69408-81-7",57,201.18,"<1",0,"http://selleckchem.com/products/Amonafide.html","C16H17N3O2","free base","NSC308847,AS1413","CN(C)CCN1C(=O)C2=C3C(=CC=C2)C=C(N)C=C3C1=O",1.162,2,1,3]
["S1368","Acitretin","b8","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.5;Martindale:The Extra Pharmacopoeia","091455,202148,202552,202897,203707,204633","Immunology","Retinoid Receptor","Metabolism","Acitretin (Etretin, RO 10-1670) is a second generation retinoid used for psoriasis.",326.43,"55079-83-9",20,61.27,"<1",0,"http://selleckchem.com/products/Acitretin.html","C21H26O3","free base","Etretin, RO 10-1670","COC1=CC(=C(\\C=C\\C(C)=C\\C=C\\C(C)=C\\C(O)=O)C(=C1C)C)C",5.665,2,0,6]
["S1373","Daptomycin (LY146032)","c8","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","091039,202857,203797,205037,206005,206077,208375,208385,209949","Infection","Antibiotics,Antibiotics for Mammalian Cell Culture,Bacterial,DNA/RNA Synthesis","DNA Damage/DNA Repair","Daptomycin (Cubicin,LY146032) is a novel antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.",1620.67,"103060-53-3",100,61.7,100,61.7,"http://selleckchem.com/products/Daptomycin.html","C72H101N17O26","free base","Cubicin,LY146032","CCCCCCCCCC(=O)NC(CC1=C[NH]C2=C1C=CC=C2)C(=O)NC(CC(N)=O)C(=O)NC(CC(O)=O)C(=O)NC3C(C)OC(=O)C(CC(=O)C4=CC=CC=C4N)NC(=O)C(NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CCCN)NC(=O)CNC3=O)C(C)CC(O)=O",-7.895,21,18,35]
["S1374","Doripenem Hydrate","d8","L1300-02","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","022106","Infection","Antibiotics","Microbiology","Doripenem Hydrate (S-4661) is an ultra-broad-spectrum injectable antibiotic, used to treat complicated intra-abdominal infections and complicated urinary tract infections.",438.52,"364622-82-2",36,82.09,26,59.29,"http://selleckchem.com/products/Doripenem-Hydrate.html","C15H24N4O6S2.H2O","Hydrate","S-4661","O.CC(O)C1C2C(C)C(=C(N2C1=O)C(O)=O)SC3CNC(CN[S](N)(=O)=O)C3",-5.546,4,4,7]
["S1376","Gestodene","e8","L1300-02","in 10mM DMSO","DMF,CFDA,NDC,HMA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Gestodene (SH B 331,WL 70) is a progestogen hormonal contraceptive.",310.43,"60282-87-3",62,199.72,"<1",0,"http://selleckchem.com/products/Gestodene.html","C21H26O2","free base","SH B 331,WL 70","CCC12CCC3C(CCC4=CC(=O)CCC34)C1C=CC2(O)C#C",4.462,1,0,1]
["S1377","Drospirenone","f8","L1300-02","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","077527,078515,078833,090081,201663,202131,202594,203291,204296,204848,205876,207245,209423,210017,211944,203593,203594,205947","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Drospirenone (ZK 3059) is a synthetic progestin that is an analog to spironolactone.",366.49,"67392-87-4",73,199.19,"<1",0,"http://selleckchem.com/products/Drospirenone.html","C24H30O3","free base","ZK 3059","CC12CCC(=O)C=C1C3CC3C4C2CCC5(C)C4C6CC6C57CCC(=O)O7",3.383,3,0,0]
["S1378","Ruxolitinib (INCB018424)","g8","L1300-02","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"202192","Hematology","Apoptosis related,Autophagy,JAK,Mitophagy","JAK/STAT","Ruxolitinib (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis.",306.37,"941678-49-5",61,199.11,"<1",0,"http://selleckchem.com/products/INCB18424.html","C17H18N6","free base","INCB018424","N#CCC(C1CCCC1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4",2.88,3,1,4]
["S1379","Isotretinoin","h8","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.5;Martindale:The Extra Pharmacopoeia","207792","Cancer","Hydroxylase","Metabolism","Isotretinoin (13-cis retinoic acid) was developed to be used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more.",300.44,"4759-48-2",60,199.71,"<1",0,"http://selleckchem.com/products/Isotretinoin.html","C20H28O2","free base","13-cis retinoic acid","CC1=C(\\C=C\\C(C)=C\\C=C\\C(C)=C/C(O)=O)C(C)(C)CCC1",5.551,1,0,5]
["S1380","Lopinavir (ABT-378)","a9","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","205425,207407,204739,079074,090371,090471,091202,091203,091677,210540","Infection","COVID-19,HIV Protease","Proteases","Lopinavir (ABT-378) is a potent HIV protease inhibitor with Ki of 1.3 pM in a cell-free assay.",628.8,"192725-17-0",126,200.38,"<1",0,"http://selleckchem.com/products/Lopinavir.html","C37H48N4O5","free base","ABT-378","CC(C)C(N1CCCNC1=O)C(=O)NC(CC(O)C(CC2=CC=CC=C2)NC(=O)COC3=C(C)C=CC=C3C)CC4=CC=CC=C4",4.926,4,4,15]
["S1381","Meropenem","b9","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia","090940,091201,091404,204139,204854,205835,205883,206086,206141,202106","Infection/Respiratory Disease","Antibiotics","Microbiology","Meropenem (SM 7338) is an ultra-broad spectrum injectable antibiotic.",383.46,"96036-03-2",76,198.2,8,20.86,"http://selleckchem.com/products/Meropenem.html","C17H25N3O5S","free base","SM 7338","CC(O)C1C2C(C)C(=C(N2C1=O)C(O)=O)SC3CNC(C3)C(=O)N(C)C",-4.129,3,2,5]
["S1382","Mianserin HCl","c9","L1300-02","in 10mM DMSO","DMF,CFDA,PMDA","BP2019;EP9.2;IP2010",null,"Neurological Disease","Histamine Receptor","Neuronal Signaling","Mianserin (Bolvidon, Norval, Tolvon,ORG GB-94 HCl,Mianserin hydrochloride) is an potent antagonist of H1 histamine receptor and 5-HT serotonin receptors, used for the treatment of depression.",300.83,"21535-47-7",60,199.45,30,99.72,"http://selleckchem.com/products/mianserin-hydrochloride.html","C18H20N2.HCl","Hydrochloride","Bolvidon, Norval, Tolvon,ORG GB-94 HCl,Mianserin hydrochloride","Cl.CN1CCN2C(C1)C3=C(CC4=C2C=CC=C4)C=CC=C3",4.088,0,0,0]
["S1385","Mosapride Citrate","d9","L1300-02","in 10mM DMSO","DMF,CFDA,PMDA","KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia",null,"Gastrointestinal Disease","5-HT Receptor","Neuronal Signaling","Mosapride Citrate (TAK-370, AS-4370, Gasmotin) is a gastroprokinetic agent that acts as a selective 5HT4 agonist.",614.02,"112885-42-4",90,146.58,"<1",0,"http://selleckchem.com/products/Mosapride-citrate.html","C21H25ClFN3O3.C6H8O7","Citrate","TAK-370, AS-4370, Gasmotin","CCOC1=CC(=C(Cl)C=C1C(=O)NCC2CN(CCO2)CC3=CC=C(F)C=C3)N.OC(=O)CC(O)(CC(O)=O)C(O)=O",-1.422,6,2,12]
["S1386","Nafamostat mesilate (FUT-175)","e9","L1300-02","in 10mM DMSO","PMDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Infection/Hematology","Apoptosis related,COVID-19,SARS-CoV,Serine Protease","Proteases","Nafamostat mesilate (Futhan, FUT-175) is a synthetic serine protease inhibitor, used as an anticoagulant during hemodialysis. Nafamostat mesylate blocks activation of SARS-CoV-2 and is investigated as a new treatment option for COVID-19. Nafamostat Mesilate attenuates inflammation and apoptosis.",539.58,"82956-11-4",20,37.07,53,98.22,"http://selleckchem.com/products/Nafamostat-mesylate.html","C19H17N5O2.2CH4O3S","Dimesylate","Futhan, FUT-175","C[S](O)(=O)=O.C[S](O)(=O)=O.NC(=N)NC1=CC=C(C=C1)C(=O)OC2=CC3=C(C=C2)C=C(C=C3)C(N)=N",1.364,2,3,6]
["S1387","Naftopidil DiHCl","f9","L1300-02","in 10mM DMSO","DMF,CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Others","Adrenergic Receptor","Neuronal Signaling","Naftopidil DiHCl (Flivas, KT-611, Avishot,BM-15275) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.",465.41,"57149-08-3",41,88.09,"<1",0,"http://selleckchem.com/products/Naftopidil-Dihydrochloride.html","C24H28N2O3.2HCl","Dihydrochloride","Flivas, KT-611, Avishot,BM-15275","Cl.Cl.COC1=CC=CC=C1N2CCN(CC2)CC(O)COC3=C4C=CC=CC4=CC=C3",4.726,2,1,7]
["S1389","Omeprazole","g9","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.7;BP2019;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","022032,075347,075410,075576,075757,075785,075791,075876,076048,076515,078490,091352,091672,202384,203270,203481,204661,205070,206582,207740,207891,209400,210070","Cancer/Gastrointestinal Disease","ATPase,Autophagy,Proton Pump","Transmembrane Transporters","Omeprazole is a proton pump inhibitor that blocks H(+)-K(+)-ATPase, used to treat dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, laryngopharyngeal reflux, and Zollinger–Ellison syndrome.",345.42,"73590-58-6",69,199.76,"<1",0,"http://selleckchem.com/products/Omeprazole.html","C17H19N3O3S","free base","N/A","COC1=CC=C2[NH]C(=NC2=C1)[S](=O)CC3=C(C)C(=C(C)C=N3)OC",2.904,5,1,5]
["S1390","Ondansetron HCl","h9","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","076183,076252,076695,076781,076876,076930,076930,076960,076967,076974,077009,077050,077112,077172,077303,077306,077365,077368,077430,077473,077517,077535,077544,077545,077577,077582,077729,077840,077851,078127,078180,078257,078288,078539,078776,079039,079224,090116,090424,090648,090883,091342,091483,202599,203711,203761,204906,206846","Gastrointestinal Disease","5-HT Receptor","Neuronal Signaling","Ondansetron HCl (Ondemet, Emeset, Emetron,GR 38032F,SN 307) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation therapy.",329.82,"99614-01-4",66,200.11,24,72.77,"http://selleckchem.com/products/Ondansetron-hydrochloride.html","C18H19N3O.HCl","Hydrochloride","Ondemet, Emeset, Emetron,GR 38032F,SN 307","Cl.C[N]1C2=C(C(=O)C(CC2)C[N]3C=CN=C3C)C4=CC=CC=C14",3.016,2,0,2]
["S1391","Oxcarbazepine","a10","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","077747,077794,077795,077801,077802,078005,078069,078734,090239,201193,202961,205444,206576","Neurological Disease","Sodium Channel","Transmembrane Transporters","Oxcarbazepine (GP47680) inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM.",252.27,"28721-07-5",7,27.75,"<1",0,"http://selleckchem.com/products/Oxcarbazepine.html","C15H12N2O2","free base","GP47680","NC(=O)N1C2=C(CC(=O)C3=C1C=CC=C3)C=CC=C2",2.131,2,1,0]
["S1393","Pirarubicin (NSC-333054)","b10","L1300-02","in 10mM DMSO","DMF,CFDA","KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia",null,"Cancer","Antineoplastic and Immunosuppressive Antibiotics,Topoisomerase","DNA Damage/DNA Repair","Pirarubicin (NSC-333054,THP) is an anthracycline antibiotic, and also a DNA/RNA synthesis inhibitor by intercalating into DNA and interacts with topoisomerase II, used as an antineoplastic agent.",627.64,"72496-41-4",7,11.15,"<1",0,"http://selleckchem.com/products/Pirarubicin.html","C32H37NO12","free base","NSC-333054,THP","COC1=CC=CC2=C1C(=O)C3=C(O)C4=C(CC(O)(CC4OC5CC(N)C(OC6CCCCO6)C(C)O5)C(=O)CO)C(=C3C2=O)O",1.091,8,4,7]
["S1394","Pizotifen Malate","c10","L1300-02","in 10mM DMSO","CFDA","BP2019;Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","5-HT Receptor","Neuronal Signaling","Pizotifen Malate (Sandomigran, pizotyline,BC-105) is a benzocycloheptane based agent used for recurrent migraine headaches.",429.53,"5189-11-7",21,48.89,"<1",0,"http://selleckchem.com/products/Pizotifen-malate.html","C19H21NS.C4H6O5","Malate","Sandomigran, pizotyline,BC-105","CN1CCC(CC1)=C2C3=C(CCC4=C2C=CC=C4)SC=C3.OC(CC(O)=O)C(O)=O",0.292,2,1,3]
["S1396","Resveratrol (SRT501)","d10","L1300-02","in 10mM DMSO","DMF,NDC","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Cancer/Cardiovascular Disease/Inflammation","AMPK,Apoptosis related,Autophagy,COX,ERK,IκB/IKK,JNK,Lipoxygenase,Mitophagy,Sirtuin,Src,STAT","Autophagy","Resveratrol (SRT501, trans-Resveratrol) has a wide spectrum of targets including cyclooxygenases(i.e. COX, IC50=1.1 μM), lipooxygenases（LOX, IC50=2.7 μM）, kinases, sirtuins and other proteins. It has anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects. Resveratrol induces mitophagy/autophagy and autophagy-dependent apoptosis.",228.24,"501-36-0",45,197.16,"<1",0,"http://selleckchem.com/products/Resveratrol.html","C14H12O3","free base","trans-Resveratrol,SRT501","OC1=CC=C(C=C1)\\C=C\\C2=CC(=CC(=C2)O)O",3.09,0,3,2]
["S1397","Rocuronium Bromide","e10","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","078519,078651,078717,079195,079199,091115,091458,204679,205656,206206","Neurological Disease","AChR","Neuronal Signaling","Rocuronium Bromide (ORG 9426) is a competitive AchR antagonist, used in modern anaesthesia.",609.68,"119302-91-9",122,200.1,122,200.1,"http://selleckchem.com/products/Rocuronium-bromide.html","C32H53N2O4.Br","Bromide","ORG 9426","[Br-].CC(=O)OC1C(CC2C3CCC4CC(O)C(CC4(C)C3CCC12C)N5CCOCC5)[N+]6(CCCC6)CC=C",0.282,3,1,6]
["S1398","Stavudine (d4T)","f10","L1300-02","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;IP2010","077672,077774,078030,078256,078587,078775,078957,079069","Infection","Reverse Transcriptase","Microbiology","Stavudine (d4T, BMY-27857, Sanilvudine, NSC 163661) is a nucleoside analog reverse transcriptase inhibitor (NARTI) active against HIV.",224.21,"3056-17-5",45,200.7,"<1",0,"http://selleckchem.com/products/Stavudine.html","C10H12N2O4","free base","BMY-27857, Sanilvudine, NSC 163661,d4T","CC1=CN(C2OC(CO)C=C2)C(=O)NC1=O",-0.515,3,2,2]
["S1400","Tenofovir (GS 1278) Disoproxil Fumarate","g10","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","078800,079071,090636,090647,090742,091612,203232,203470,204402,206481,206569,209498,209550","Infection","HIV,Reverse Transcriptase","Microbiology","Tenofovir Disoproxil Fumarate (Tenofovir DF,GS-1278 Disoproxil Fumarate) belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination.",635.51,"202138-50-9",100,157.35,"<1",0,"http://selleckchem.com/products/Tenofovir-Disoproxil-Fumarate.html","C19H30N5O10P.C4H4O4","Fumarate","Tenofovir DF,GS-1278 Disoproxil Fumarate","CC(C)OC(=O)OCO[P](=O)(COC(C)C[N]1C=NC2=C1N=CN=C2N)OCOC(=O)OC(C)C.OC(=O)/C=C/C(O)=O",1.729,14,1,19]
["S1401","Tenofovir","h10","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","078800,079071,090636,090647,090742,091612,203232,203470,204402,206481,206569,209498,209550","Infection","Antiviral,COVID-19,Reverse Transcriptase","Microbiology","Tenofovir (GS-1278) blocks reverse transcriptase and hepatitis B virus infections.",287.21,"147127-20-6",4,13.93,2,6.96,"http://selleckchem.com/products/Tenofovir.html","C9H14N5O4P","free base","GS-1278","CC(C[N]1C=NC2=C(N)N=CN=C12)OC[P](O)(O)=O",-0.772,4,1,5]
["S1403","Tigecycline (GAR-936)","a11","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.4;EP9.4;Martindale:The Extra Pharmacopoeia","091620,204439,205645,208744,211158","Infection","Antineoplastic and Immunosuppressive Antibiotics,Autophagy,Bacterial","Microbiology","Tigecycline (Tygacil, GAR-936, WAY-GAR-936, TBG-MINO) is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline induces autophagy by downregulating the PI3K-AKT-mTOR pathway.",585.65,"220620-09-7",100,170.75,100,170.75,"http://selleckchem.com/products/Tigecycline.html","C29H39N5O8","free base","Tygacil, GAR-936, WAY-GAR-936, TBG-MINO","CN(C)C1C2CC3CC4=C(C(=C(NC(=O)CNC(C)(C)C)C=C4N(C)C)O)C(=O)C3=C(O)C2(O)C(=O)C(=C1O)C(N)=O",-0.381,4,6,7]
["S1404","Trilostane","b11","L1300-02","in 10mM DMSO","FDA,DMF,PMDA","Martindale:The Extra Pharmacopoeia","018719","Metabolic Disease","Dehydrogenase","Metabolism","Trilostane (WIN 24540) is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing’s syndrome.",329.43,"13647-35-3",65,197.31,"<1",0,"http://selleckchem.com/products/Trilostane.html","C20H27NO3","free base","WIN 24540","CC12CCC3C(CCC45OC4C(=C(CC35C)C#N)O)C1CCC2O",2.434,1,2,0]
["S1405","Vecuronium Bromide","c11","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.2;BP2019;Martindale:The Extra Pharmacopoeia","074334,074688,075164,075218,075549,075558,078274,079001,090243,205390,206670","Neurological Disease","AChR","Neuronal Signaling","Vecuronium Bromide (ORG NC45) is a non-depolarizing neuromuscular blocking agent, used for skeletal muscle relaxation during surgery.",637.73,"50700-72-6",100,156.81,4,6.27,"http://selleckchem.com/products/Vecuronium-Bromide.html","C34H57N2O4.Br","Bromide","ORG NC45","[Br-].CC(=O)OC1CC2CCC3C(CCC4(C)C3CC(C4OC(C)=O)[N+]5(C)CCCCC5)C2(C)CC1N6CCCCC6",1.73,4,0,6]
["S1407","Bimatoprost","d11","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","USP;Martindale:The Extra Pharmacopoeia","090449,200487,201894,202565,202719,203051,203056,203299,203404,203604,203991,209797,210126,210263,210515","Ophthalmology","Prostaglandin Receptor","GPCR & G Protein","Bimatoprost(AGN 192024) is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.",415.57,"155206-00-1",36,86.63,"<1",0,"http://selleckchem.com/products/Bimatoprost.html","C25H37NO4","free base","AGN 192024","CCNC(=O)CCC\\C=C/CC1C(O)CC(O)C1/C=C/C(O)CCC2=CC=CC=C2",3.03,1,4,12]
["S1408","Linezolid (PNU-100766)","e11","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;IP2010;Martindale:The Extra Pharmacopoeia","078061,078845,078987,091210,200068,200222,200904,204239,204536,204696,204764,205154,205233,205442,205517,206097,206917,207001,207354,207526,210702","Infection/Respiratory Disease","Antibiotics","Microbiology","Linezolid (Zyvoxid, Zyvoxam,PNU-100766) is a synthetic antibiotic used for the treatment of serious infections.",337.35,"165800-03-3",67,198.61,"<1",0,"http://selleckchem.com/products/Linezolid(Zyvox).html","C16H20FN3O4","free base","Zyvoxid, Zyvoxam,PNU-100766","CC(=O)NCC1CN(C(=O)O1)C2=CC=C(N3CCOCC3)C(=C2)F",0.894,4,1,4]
["S1409","Alfuzosin HCl","f11","L1300-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;EP9.1;BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia","079013,079014,079054,079056,079057,079060,090221,090284,203192","Others","Adrenergic Receptor","Neuronal Signaling","Alfuzosin HCI(SL 77499 HCl)  is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH).",425.91,"81403-68-1",85,199.57,85,199.57,"http://selleckchem.com/products/Alfuzosin-hydrochloride.html","C19H27N5O4.HCl","Hydrochloride","SL 77499 HCl","Cl.COC1=C(OC)C=C2C(=NC(=NC2=C1)N(C)CCCNC(=O)C3CCCO3)N",1.8,6,2,8]
["S1415","Clopidogrel (SR-25990C) Bisulfate","g11","L1300-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","076273,076274,076999,077665,078004,078133,090307,090494,090540,090625,090844,091023,091216,201686,202266,202925,202928,203751,204165,204359,206376","Cardiovascular Disease","P2 Receptor","Neuronal Signaling","Clopidogrel Bisulfate (SR-25990C, Clopidogrel hydrogen sulfate, Iscover, Plavix) is an oral, thienopyridine class antiplatelet agent.",419.9,"120202-66-6",83,197.67,78,185.76,"http://selleckchem.com/products/Clopidogrel-bisulfate.html","C16H16ClNO2S.H2SO4","Bisulfate","SR-25990C, Clopidogrel hydrogen sulfate, Iscover, Plavix","COC(=O)C(N1CCC2=C(C1)C=CS2)C3=C(Cl)C=CC=C3.O[S](O)(=O)=O",3.128,2,0,4]
["S1425","Ranolazine 2HCl","h11","L1300-02","in 10mM DMSO","FDA,DMF,EMA,NDC","Martindale:The Extra Pharmacopoeia","201046,208174,208862,209081,210054,211291,211707","Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Ranolazine 2HCl (RS-43285,RS 43285-193,Ranexa, renolazine,Ranolazine dihydrochloride) is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina.",500.46,"95635-56-6",100,199.82,100,199.82,"http://selleckchem.com/products/Ranolazine-dihydrochloride.html","C24H33N3O4.2HCl","Dihydrochloride","RS-43285,RS 43285-193,Ranexa, renolazine,Ranolazine dihydrochloride","Cl.Cl.COC1=CC=CC=C1OCC(O)CN2CCN(CC2)CC(=O)NC3=C(C)C=CC=C3C",3.755,3,2,9]
["S1426","Repaglinide","a2","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Martindale:The Extra Pharmacopoeia","077571,077571,078555,090008,090252,,091517,201189,203820","Endocrinology/Metabolic Disease","Potassium Channel","Transmembrane Transporters","Repaglinide (AG-EE 623 ZW) is a potassium channel blocker, which lowers blood glucose by stimulating the release of insulin from the pancreas, used the treatment of type II diabetes.",452.59,"135062-02-1",91,201.06,"<1",0,"http://selleckchem.com/products/Repaglinide.html","C27H36N2O4","free base","AG-EE 623 ZW","CCOC1=C(C=CC(=C1)CC(=O)NC(CC(C)C)C2=CC=CC=C2N3CCCCC3)C(O)=O",5.307,3,1,10]
["S1430","Rolipram (ZK-62711)","b2","L1300-03","in 10mM DMSO","DMF",null,null,"Neurological Disease","PDE","Metabolism","The PDE4 selective inhibitor, Rolipram (ZK-62711, SB 95952), inhibited immunopurified PDE4B and PDE4D activities similarly, with IC50 values of approx. 130 nM and 240 nM respectively; an anti-inflammatory agent.",275.34,"61413-54-5",55,199.75,"<1",0,"http://selleckchem.com/products/Rolipram.html","C16H21NO3","free base","ZK-62711, SB 95952","COC1=C(OC2CCCC2)C=C(C=C1)C3CNC(=O)C3",2.349,3,1,4]
["S1431","Sildenafil Citrate","c2","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.2;BP2019;IP2010;Martindale:The Extra Pharmacopoeia","077342,078380,091378,091379,091448,091479,200149,200165,201150,201171,202023,202025,202255,202503,202506,202597,202598,202659,203623,203814,203962,203963,203988,204882,204883,206401,207178,208494,210394,212051,212260","Others","PDE","Metabolism","Sildenafil Citrate, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), is a well-tolerated and highly effective treatment for erectile dysfunction.",666.7,"171599-83-0",20,30,"<1",0,"http://selleckchem.com/products/Sildenafil-citrate.html","C22H30N6O4S.C6H8O7","Citrate","N/A","CCCC1=N[N](C)C2=C1N=C(NC2=O)C3=CC(=CC=C3OCC)[S](=O)(=O)N4CCN(C)CC4.OC(=O)CC(O)(CC(O)=O)C(O)=O",-2.107,9,1,12]
["S1432","Sumatriptan Succinate","d2","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","076554,076572,076840,076847,076933,076976,077163,077332,077696,077744,077871,077907,078067,078241,078284,078295,078298,078318,078319,078327,078593,079123,079240,079242,090310,090314,090358,090495,090641,200183,200263,202758,203322","Neurological Disease","5-HT Receptor","Neuronal Signaling","Sumatriptan Succinate (GR 43175) is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches.",413.49,"103628-48-4",83,200.73,83,200.73,"http://selleckchem.com/products/Sumatriptan-succinate.html","C14H21N3O2S.C4H6O4","Succinate","GR 43175","CN[S](=O)(=O)CC1=CC=C2[NH]C=C(CCN(C)C)C2=C1.OC(=O)CCC(O)=O",-1.958,4,2,9]
["S1435","Tamsulosin hydrochloride","e2","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","078015,078225,078801,078938,090377,090408,090931,202010,202433,204645,207405","Others","Adrenergic Receptor","Neuronal Signaling","Tamsulosin (Flomax) hydrochloride is an antagonist of alpha1A adrenoceptors in the prostate.",444.97,"106463-17-6",89,200.01,"<1",0,"https://www.selleckchem.com/products/Tamsulosin-hydrochloride.html","C20H28N2O5S.HCl","HCl","Flomax hydrochloride","CCOC1=C(OCCNC(C)CC2=CC=C(OC)C(=C2)[S](N)(=O)=O)C=CC=C1",2.719,5,2,11]
["S1437","Tizanidine HCl","f2","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","076280,076281,076282,076283,076284,076286,076321,076347,076354,076371,076416,076533,078868,091283,091502,207170,207199,208187,208622,209605,210021,210267,211798,212196","Neurological Disease","Adrenergic Receptor","Neuronal Signaling","Tizanidine HCl (DS 103-282) is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.",290.17,"64461-82-1",10,34.46,15,51.69,"http://selleckchem.com/products/Tizanidine-hydrochloride.html","C9H8ClN5S.HCl","Hydrochloride","DS 103-282","Cl.ClC1=C(NC2=NCCN2)C3=NSN=C3C=C1",2.199,3,2,2]
["S1438","Topiramate","g2","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;IP2010;Martindale:The Extra Pharmacopoeia","076306,076311,076314,076315,076317,076327,076343,076448,076575,077627,077643,077733,077868,077905,078235,078410,078418,078462,078499,078637,078877,079153,079162,079206,090162,090278,090353,091185,205976,207382,210278","Neurological Disease","Carbonic Anhydrase","Metabolism","Topiramate (MCN 4853, RWJ 17021) is a mutil-targeted inhibitor, including voltage-gated sodium channel and calcium channel, AMPA/kainate receptor and carbonic anhydrase, used to treat epilepsy.",339.36,"97240-79-4",68,200.38,"<1",0,"http://selleckchem.com/products/Topiramate.html","C12H21NO8S","free base","MCN 4853, RWJ 17021","CC1(C)OC2COC3(CO[S](N)(=O)=O)OC(C)(C)OC3C2O1",-1.932,6,1,3]
["S1439","Tranilast (SB 252218)","h2","L1300-03","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Immunology","Immunology & Inflammation related","Immunology & Inflammation","Tranilast (SB 252218, MK-341, Rizaben, MK 341, Tranpro) is an antiallergic drug by inhibiting lipid mediator and cytokine release from inflammatory cells, used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.",327.33,"53902-12-8",66,201.63,"<1",0,"http://selleckchem.com/products/Tranilast.html","C18H17NO5","free base","SB 252218, MK-341, Rizaben, MK 341, Tranpro","COC1=C(OC)C=C(\\C=C\\C(=O)NC2=CC=CC=C2C(O)=O)C=C1",2.679,4,1,6]
["S1441","Venlafaxine HCl","a3","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","022104,076565,076690,077166,077515,077653,078057,078087,078301,078421,078517,078554,078627,078789,078865,078932,079098,090027,090071,090174,090555,090899,091123,091272,200834,201272,202036,204889,205468,206250","Neurological Disease","Serotonin Transporter","Neuronal Signaling","Venlafaxine HCl(Wy 453 HCl) is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.",313.86,"99300-78-4",55.5,176.83,55.5,176.83,"http://selleckchem.com/products/Venlafaxine-hydrochloride.html","C17H27NO2.HCl","Hydrochloride","Wy 453 HCl","Cl.COC1=CC=C(C=C1)C(CN(C)C)C2(O)CCCCC2",3.404,1,0,5]
["S1442","Voriconazole (UK-109496)","b3","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","090547,090862,091658,200265,202361,203503,205034,206181,206398,206654,206747,206762,206799,206837,207049,207371,208562,208983,211661","Infection","Fungal,P450 (e.g. CYP17)","Metabolism","Voriconazole (Vfend,UK-109496) is a new triazole derivative similar to fluconazole and itraconazole that acts by inhibiting fungal cytochrome P-450-dependent, 14-alpha-sterol demethylase-mediated synthesis of ergosterol.",349.31,"137234-62-9",70,200.4,"<1",0,"http://selleckchem.com/products/Voriconazole.html","C16H14F3N5O","free base","Vfend,UK-109496","CC(C1=NC=NC=C1F)C(O)(C[N]2C=NC=N2)C3=CC=C(F)C=C3F",2.071,4,0,5]
["S1443","Zileuton (A-64077)","c3","L1300-03","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","204929","Inflammation","Apoptosis related,Ferroptosis,Lipoxygenase","Metabolism","Zileuton (A-64077, Abbott 64077, ZYFLO) is an orally active inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation, used to decrease the symptoms of asthma. Zileuton induces apoptosis while inhibits ferroptosis.",236.29,"111406-87-2",47,198.91,"<1",0,"http://selleckchem.com/products/Zileuton.html","C11H12N2O2S","free base","A-64077, Abbott 64077, ZYFLO","CC(N(O)C(N)=O)C1=CC2=CC=CC=C2S1",2.184,1,1,2]
["S1444","Ziprasidone HCl","d3","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","077560,077561,077562,077565,090348,202395,204117,204375,208988","Neurological Disease","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Ziprasidone HCl (CP-88059) is a novel and potent dopamine and serotonin (5-HT) receptor antagonist, used in the treatment of schizophrenia and bipolar disorder.",449.4,"122883-93-6",90,200.27,"<1",0,"http://selleckchem.com/products/Ziprasidone-hydrochloride.html","C21H21ClN4OS.HCl","Hydrochloride","CP-88059","Cl.ClC1=CC2=C(CC(=O)N2)C=C1CCN3CCN(CC3)C4=NSC5=C4C=CC=C5",4.641,2,1,4]
["S1445","Zonisamide","e3","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","077625,077634,077635,077636,077637,077639,077641,077642,077644,077645,077647,077648,077650,077651,077813,077869,077876","Neurological Disease","Sodium Channel","Transmembrane Transporters","Zonisamide (Zonegran,CI-912,AD 810) is a voltage-dependent sodium channel and T-type calcium channel blocker, used as an antiepileptic drug.",212.23,"68291-97-4",42,197.9,"<1",0,"http://selleckchem.com/products/Zonisamide.html","C8H8N2O3S","free base","Zonegran,CI-912,AD 810","N[S](=O)(=O)CC1=NOC2=CC=CC=C12",0.411,4,1,2]
["S1453","Tipifarnib (R115777)","f3","L1300-03","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Cancer","FTase,Transferase","Metabolism","Tipifarnib (R115777, IND 58359) is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM, its anti-proliferative effects are most prominent in H-ras or N-ras mutant cells. Phase 3.",489.4,"192185-72-1",14,28.61,"<1",0,"http://selleckchem.com/products/Tipifarnib(R115777).html","C27H22Cl2N4O","free base","IND 58359","C[N]1C=NC=C1C(N)(C2=CC=C(Cl)C=C2)C3=CC4=C(C=C3)N(C)C(=O)C=C4C5=CC(=CC=C5)Cl",4.808,2,1,4]
["S1457","Atazanavir (BMS-232632) Sulfate","g3","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","EP9.7;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","078785,091611,091673,200196,200626,204806,208177","Infection","HIV Protease","Proteases","Atazanavir Sulfate (BMS-232632-05, Reyataz) is a HIV protease inhibitor with Ki of 2.66 nM in a cell-free assay.",802.93,"229975-97-7",104,129.53,"<1",0,"http://selleckchem.com/products/Atazanavir.html","C38H52N6O7.H2SO4","Sulfate","BMS-232632-05, Reyataz","COC(=O)NC(C(=O)NC(CC1=CC=CC=C1)C(O)CN(CC2=CC=C(C=C2)C3=NC=CC=C3)NC(=O)C(NC(=O)OC)C(C)(C)C)C(C)(C)C.O[S](O)(=O)=O",4.083,7,5,18]
["S1458","Neflamapimod (VX-745)","h3","L1300-03","in 10mM DMSO","DMF",null,null,"Neurological Disease/Inflammation","p38 MAPK","MAPK","Neflamapimod (VX-745) is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ.",436.26,"209410-46-8",15,34.38,"<1",0,"http://selleckchem.com/products/VX-745.html","C19H9Cl2F2N3OS","free base","N/A","FC1=CC(=C(SC2=NN3C=NC(=O)C(=C3C=C2)C4=C(Cl)C=CC=C4Cl)C=C1)F",5.342,3,0,3]
["S1465","Moxifloxacin (BAY12-8039) HCl","a4","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.8;BP2019;Martindale:The Extra Pharmacopoeia","076938,077437,078073,090080,200160,202525,202632,202867,202916,204079,204635,205348,205572,206242,206295,207285,208682,209469","Infection/Inflammation","Topoisomerase","DNA Damage/DNA Repair","Moxifloxacin (Avelox, Avalox,BAY12-8039 HCl) is a fourth-generation synthetic fluoroquinolone antibacterial agent.",437.89,"186826-86-8",87,198.68,60,137.02,"https://www.selleckchem.com/products/Moxifloxacin-hcl.html","C21H24FN3O4.HCl","Hydrochloride","Avelox, Avalox,BAY12-8039 HCl","Cl.COC1=C2N(C=C(C(O)=O)C(=O)C2=CC(=C1N3CC4CCCNC4C3)F)C5CC5",-0.32,3,1,4]
["S1467","Doxercalciferol","b4","L1300-03","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","090040,091101,091333,091433,200926,201518,203929,208614,208974,208975,210801","Endocrinology/Metabolic Disease","Vitamin","Metabolism","Doxercalciferol (1α-hydroxyvitamin D2) is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.",412.65,"54573-75-0",83,201.14,"<1",0,"http://selleckchem.com/products/Doxercalciferol(Hectorol).html","C28H44O2","free base","1α-hydroxyvitamin D2","CC(C)C(C)/C=C/C(C)C1CCC2C(/CCCC12C)=C/C=C/3CC(O)CC(O)C3=C",6.337,0,2,5]
["S1468","Alfacalcidol","c4","L1300-03","in 10mM DMSO","CFDA,PMDA,HMA","BP2019;EP9.2;KP Ⅹ;Martindale:The Extra Pharmacopoeia",null,"Metabolic Disease","Vitamin","Metabolism","Alfacalcidol (1-hydroxycholecalciferol) is a non-selective VDR activator medication.",400.64,"41294-56-8",80,199.68,"<1",0,"http://selleckchem.com/products/Alfacalcidol.html","C27H44O2","free base","1-hydroxycholecalciferol","CC(C)CCCC(C)C1CCC2/C(CCCC12C)=C\\C=C3/CC(O)CC(O)C3=C",6.53,0,2,6]
["S1472","Safinamide Mesylate","d4","L1300-03","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"207145","Cardiovascular Disease/Neurological Disease","MAO","Metabolism","Safinamide Mesylate (PNU-151774E, FCE28073) is mesylate salt of Safinamide, selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A. Phase 3.",398.45,"202825-46-5",80,200.78,80,200.78,"http://selleckchem.com/products/Safinamide-mesilate.html","C17H19FN2O2.CH4O3S","Mesylate","PNU-151774E,FCE28073","CC(NCC1=CC=C(OCC2=CC(=CC=C2)F)C=C1)C(N)=O.C[S](O)(=O)=O",2.064,2,2,7]
["S1482","Daclatasvir (BMS-790052)","e4","L1300-03","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"206843","Infection","HCV Protease","Proteases","Daclatasvir (BMS-790052, EBP883) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. Phase 3.",738.88,"1009119-64-5",148,200.3,"<1",0,"http://selleckchem.com/products/BMS-790052.html","C40H50N8O6","free base","EBP883","COC(=O)NC(C(C)C)C(=O)N1CCCC1C2=NC=C([NH]2)C3=CC=C(C=C3)C4=CC=C(C=C4)C5=CN=C([NH]5)C6CCCN6C(=O)C(NC(=O)OC)C(C)C",5.048,8,4,13]
["S1483","Iloperidone","f4","L1300-03","in 10mM DMSO","FDA,DMF,EMA,NDC","USP","207231,207409","Neurological Disease","5-HT Receptor","Neuronal Signaling","Iloperidone (HP873) is a dopamine (D2)/serotonin (5-HT2) receptor antagonist, used for the treatment of schizophrenia.",426.48,"133454-47-4",27,63.31,"<1",0,"http://selleckchem.com/products/Iloperidone(Fanapt).html","C24H27FN2O4","free base","HP873","COC1=C(OCCCN2CCC(CC2)C3=NOC4=C3C=CC(=C4)F)C=CC(=C1)C(C)=O",4.016,5,0,8]
["S1485","HMN-214","g4","L1300-03","in 10mM DMSO","DMF",null,null,"Cancer","PLK","Cell Cycle","HMN-214 is a prodrug of HMN-176, which alters the cellular spatial orientation of Plk1.",424.47,"173529-46-9",12,28.27,"<1",0,"http://selleckchem.com/products/HMN-214.html","C22H20N2O5S","free base","N/A","COC1=CC=C(C=C1)[S](=O)(=O)N(C(C)=O)C2=C(C=CC=C2)\\C=C\\C3=CC=[N+]([O-])C=C3",2.282,4,0,6]
["S1488","Naratriptan HCl","h4","L1300-03","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","078751,090288,090381,091326,091373,091441,091552,200502,202431","Neurological Disease","5-HT Receptor","Neuronal Signaling","Naratriptan HCl is a triptan agent that is used for the treatment of migraine headaches.",371.93,"143388-64-1",74,198.96,22,59.15,"http://selleckchem.com/products/Naratriptan(Amerge).html","C17H25N3O2S.HCl","Hydrochloride","N/A","Cl.CN[S](=O)(=O)CCC1=CC=C2[NH]C=C(C3CCN(C)CC3)C2=C1",2.435,2,2,5]
["S1490","Ponatinib (AP24534)","a5","L1300-03","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"203469","Cancer/Hematology","Autophagy,Bcr-Abl,FGFR,PDGFR,Src,VEGFR","Angiogenesis","Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively. Ponatinib (AP24534) inhibits autophagy.",532.56,"943319-70-8",30,56.33,"<1",0,"http://selleckchem.com/products/AP24534.html","C29H27F3N6O","free base","AP24534","CN1CCN(CC1)CC2=C(C=C(NC(=O)C3=CC(=C(C)C=C3)C#CC4=CN=C5C=CC=N[N]45)C=C2)C(F)(F)F",4.884,3,1,7]
["S1491","Fludarabine (NSC 118218)","b5","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","022137,076349,076661,077790,078393,078544,078610,090724,200647,200648,203738","Cancer/Hematology","Apoptosis related,DNA/RNA Synthesis,Nucleoside Analog/Antimetabolite,STAT","JAK/STAT","Fludarabine (NSC 118218, FaraA, Fludarabinum) is a STAT1 activation inhibitor which causes a specific depletion of STAT1 protein (and mRNA) but not of other STATs. Also a DNA synthesis inhibitor in vascular smooth muscle cells. Fludarabine induces apoptosis.",285.23,"21679-14-1",57,199.84,"<1",0,"http://selleckchem.com/products/Fludarabine(Fludara).html","C10H12FN5O4","Free Base","FaraA, Fludarabinum, NSC 118218","NC1=NC(=NC2=C1N=C[N]2C3OC(CO)C(O)C3O)F",-1.312,4,4,2]
["S1497","Pralatrexate (NSC 754230)","c5","L1300-03","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"206167","Cancer","Apoptosis related,DHFR","Metabolism","Pralatrexate (NSC 754230) is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines. Pralatrexate induces tumor cell apoptosis.",477.47,"146464-95-1",28,58.64,"<1",0,"http://selleckchem.com/products/Pralatrexate(Folotyn).html","C23H23N7O5","free base","NSC 754230","NC1=NC(=C2N=C(CC(CC#C)C3=CC=C(C=C3)C(=O)NC(CCC(O)=O)C(O)=O)C=NC2=N1)N",1.94,7,3,10]
["S1499","Cefaclor","d5","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","062205,062206,064061,064070,064081,064085,064086,064087,064107,064110,064114,064115,064116,064145,064148,064155,064156,064164,064165,064166,064204,064205,064206,064207,065057,065058,065146,065350,065412","Infection","Antibiotics","Microbiology","Cefaclor (Cefachlor, Cefaclorum) is a cephalosporin antibiotic.",385.82,"70356-03-5",11,28.51,"<1",0,"http://selleckchem.com/products/Cefaclor-(Ceclor).html","C15H14ClN3O4S.H2O","monohydrate","Cefachlor, Cefaclorum","O.NC(C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)Cl)C3=CC=CC=C3",-2.54,3,2,4]
["S1500","Betamethasone","e5","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP38-NF33;BP2013;JP16;IP2010;Martindale:The Extra Pharmacopoeia","085738","Angiology/Cancer/Hematology/Immunology/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Betamethasone (NSC-39470, SCH-4831) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.",392.46,"378-44-9",79,201.29,"<1",0,"http://selleckchem.com/products/Betamethasone-(Celestone).html","C22H29FO5","Free Base","NSC-39470, SCH-4831","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO",1.708,2,2,2]
["S1501","Mycophenolate mofetil (RS-61443)","f5","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","065379,065410,065413,065416,065433,065451,065457,065477,065491,065520,065521,090055,090111,090253,090419,090456,090464,090499,090606,090661,090762,091249,091315,200197,203005,204076,\n204077,210181,210370","Inflammation","Apoptosis related,Dehydrogenase","Metabolism","Mycophenolate Mofetil (RS 61443, Mycophenolic acid morpholinoethyl ester, CellCept, TM-MMF) is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively. Mycophenolate Mofetil induces caspase-dependent apoptosis and cell cycle inhibition in multiple myeloma cells.",433.49,"128794-94-5",86,198.39,"<1",0,"http://selleckchem.com/products/Mycophenolate-mofetil-(CellCept).html","C23H31NO7","free base","Mycophenolic acid morpholinoethyl ester, CellCept, RS 61443, TM-MMF","COC1=C(C)C2=C(C(=O)OC2)C(=C1C\\C=C(C)\\CCC(=O)OCCN3CCOCC3)O",3.209,6,1,10]
["S1504","Dyphylline","g5","L1300-03","in 10mM DMSO","FDA,DMF","USP42-NF37","084514,084751,084566,007794,009088","Cardiovascular Disease/Immunology/Inflammation/Respiratory Disease","PDE","Metabolism","Dyphylline (Diprophylline) is a xanthine derivative with bronchodilator and vasodilator effects.",254.24,"479-18-5",51,200.6,51,200.6,"http://selleckchem.com/products/Dyphylline(Dilor).html","C10H14N4O4","free base","Diprophylline","CN1C(=O)N(C)C2=C([N](CC(O)CO)C=N2)C1=O",-1.151,3,2,3]
["S1505","Aztreonam","h5","L1300-03","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA","USP42-NF37;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","065286,065439","Infection","Antibiotics,Bacterial","Microbiology","Aztreonam (SQ 26776) is a synthetic monocyclic beta-lactam antibiotic, used to treat Gram-negative aerobic bacteria infection.",435.43,"78110-38-0",87,199.8,11,25.26,"http://selleckchem.com/products/Aztreonam(Azactam).html","C13H17N5O8S2","free base","SQ 26776","CC1C(NC(=O)\\C(=N/OC(C)(C)C(O)=O)C2=CSC(=N2)N)C(=O)N1[S](O)(=O)=O",-1.035,6,2,7]
["S1508","Alprostadil","a6","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","074815,075196","Angiology/Endocrinology","PGES","Endocrinology & Hormones","Alprostadil (Prostaglandin-E1, PGE1, Edex, Muse, Liprostin) is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It is a Prostaglandin Analog and Prostaglandin E1 Agonist.",354.48,"745-65-3",71,200.29,"<1",0,"http://selleckchem.com/products/Alprostadil(Caverject).html","C20H34O5","free base","Prostaglandin-E1, PGE1, Edex, Muse, Liprostin","CCCCCC(O)/C=C/C1C(O)CC(=O)C1CCCCCCC(O)=O",3.644,2,2,13]
["S1511","Lactulose","b6","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.8;BP2019;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","017906,071841,072029,073160,073590,073591,074076,074077,074138,074602,074623,074712,075911,075993,076645,078430,090426,090502,090503,203762,207786,209517","Others","Others","Others","Lactulose, a disaccharide composed of galactose and fructose, is a stimulator of health-promoting bacterium growth in the gastrointestinal tract, used to treat chronic constipation and hepatic encephalopathy.",342.3,"4618-18-2",68,198.66,68,198.66,"http://selleckchem.com/products/Lactulose(Enulose).html","C12H22O11","free base","N/A","OCC(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)C(=O)CO",-4.621,3,8,8]
["S1512","Tadalafil (IC351)","c6","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","090141,200630,204809,205885,206285,206286,206693,206956,206957,208824,208934,209167,209250,209539,209654,209744,209907,209908,210069,210145,210255,210392,210420,210567,210572,211335,211839,212062","Cardiovascular Disease","PDE","Metabolism","Tadalafil (IC351) is a PDE-5 inhibitor with IC50 of 1.8 nM in a cell-free assay. Tadalafil is at least 9000 times more selective for PDE5 than most of the other families of PDEs, with the exception of PDE11. It can partial inhibits PDE11",389.4,"171596-29-5",78,200.31,"<1",0,"http://selleckchem.com/products/Tadalafil(Cialis).html","C22H19N3O4","free base","IC351","CN1CC(=O)N2C(CC3=C([NH]C4=C3C=CC=C4)C2C5=CC=C6OCOC6=C5)C1=O",2.183,4,1,1]
["S1514","Cyclosporine","d6","L1300-03","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","065004,065017,065025,065040,065044,065054,065078,065110,065133,065151,065167","Cancer/Hematology/Inflammation","Immunology & Inflammation related,phosphatase","Metabolism","Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.",1202.61,"79217-60-0",100,83.15,"<1",0,"http://selleckchem.com/products/Cyclosporine.html","C62H111N11O12","free base","Neoral","CCC1NC(=O)C(C(O)C(C)C\\C=C\\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C",4.333,11,5,15]
["S1517","Natamycin","e6","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","050514","Infection/Ophthalmology","Fungal","Microbiology","Natamycin (Pimaricin), a natural and versatile anti-fungal agent during fermentation by the bacterium Streptomyces natalensis, commonly found in soil; with little to no flavour interference",665.73,"7681-93-8",7,10.51,"<1",0,"http://selleckchem.com/products/Natamycin(Pimaricin).html","C33H47NO13","free base","Pimaricin","CC1C/C=C/C=C/C=C/C=C/C(CC2OC(O)(CC(O)CC3OC3/C=C/C(=O)O1)CC(O)C2C(O)=O)OC4OC(C)C(O)C(N)C4O",-2.824,7,5,3]
["S1526","Quizartinib (AC220)","f6","L1300-03","in 10mM DMSO","EMA, PMDA",null,null,"Others","Apoptosis related,FLT3,Target Protein Ligand","Angiogenesis","Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Quizartinib (AC220) induces apoptosis of tumor cells. Phase 3.",560.67,"950769-58-1",33,58.86,"<1",0,"http://selleckchem.com/products/AC-220.html","C29H32N6O4S","free base","N/A","CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=C[N]4C(=N3)SC5=CC(=CC=C45)OCCN6CCOCC6",5.064,6,2,8]
["S1538","Telaprevir (VX-950)","g6","L1300-03","in 10mM DMSO","FDA,DMF,EMA",null,"201917","Infection","COVID-19,HCV Protease","Proteases","Telaprevir (VX-950, LY-570310, MP-424) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM.",679.85,"402957-28-2",136,200.04,"<1",0,"http://selleckchem.com/products/Telaprevir(VX-950).html","C36H53N7O6","free base","LY-570310, MP-424,VX-950","CCCC(NC(=O)C1C2CCCC2CN1C(=O)C(NC(=O)C(NC(=O)C3=NC=CN=C3)C4CCCCC4)C(C)(C)C)C(=O)C(=O)NC5CC5",2.685,8,4,14]
["S1540","Saxagliptin (BMS-477118)","h6","L1300-03","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC",null,"205902,205941,205959,205972,205994,206020","Endocrinology/Metabolic Disease","DPP","Proteases","Saxagliptin (BMS-477118, Onglyza) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.",315.41,"361442-04-8",63,199.74,63,199.74,"http://selleckchem.com/products/Saxagliptin(Onglyza).html","C18H25N3O2","Free Base","Onglyza,BMS-477118","NC(C(=O)N1C(CC2CC12)C#N)[C]34CC5[CH2]C(C[C](O)(C5)C3)C4",0.275,1,1,2]
["S1547","Febuxostat","a7","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","205385,205406,205414,205421,205443,206266,207293,210461,211339,211837","Endocrinology/Metabolic Disease","ROS","Immunology & Inflammation","Febuxostat (TMX 67, TEI-6720) is a selective xanthine oxidase inhibitor with Ki of 0.6 nM.",316.37,"144060-53-7",63,199.13,"<1",0,"http://selleckchem.com/products/Febuxostat(Uloric).html","C16H16N2O3S","free base","TMX 67, TEI-6720","CC(C)COC1=C(C=C(C=C1)C2=NC(=C(S2)C(O)=O)C)C#N",3.468,3,0,5]
["S1548","Dapagliflozin (BMS-512148)","b7","L1300-03","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"211156,211439,211442,211541","Endocrinology/Metabolic Disease","SGLT","GPCR & G Protein","Dapagliflozin (BMS-512148) is a potent and selective hSGLT2 inhibitor with EC50 of 1.1 nM, exhibiting 1200-fold selectivity over hSGLT1. Phase 4.",408.87,"461432-26-8",82,200.55,"<1",0,"http://selleckchem.com/products/Dapagliflozin.html","C21H25ClO6","free base","BMS-512148","CCOC1=CC=C(CC2=CC(=CC=C2Cl)C3OC(CO)C(O)C(O)C3O)C=C1",2.409,2,4,6]
["S1549","Nebivolol hydrochloride (R-65824)","c7","L1300-03","in 10mM DMSO","FDA,DMF,NDC,HMA","USP;IP2010;Martindale:The Extra Pharmacopoeia","203659,203683,203741,203821,203828,203966,206729","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Nebivolol HCl (R-65824) selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM.",441.9,"152520-56-4",88,199.14,"<1",0,"http://selleckchem.com/products/Nebivolol(Bystolic).html","C22H25F2NO4.HCl","Hydrochloride","R-65824 hydrochloride","Cl.OC(CNCC(O)C1CCC2=C(O1)C=CC(=C2)F)C3CCC4=CC(=CC=C4O3)F",3.939,2,3,6]
["S1550","Pimobendan","d7","L1300-03","in 10mM DMSO","PMDA","USP42-NF37 ;BP2019;EP9.5;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","PDE","Metabolism","Pimobendan (UD-CG 115 BS) is a selective inhibitor of PDE3 with IC50 of 0.32 μM.",334.37,"74150-27-9",67,200.38,"<1",0,"http://selleckchem.com/products/Pimobendan(Vetmedin).html","C19H18N4O2","free base","UD-CG 115 BS","COC1=CC=C(C=C1)C2=NC3=CC(=CC=C3[NH]2)C4=NNC(=O)CC4C",2.936,4,2,3]
["S1553","Delafloxacin (ABT-492)","e7","L1300-03","in 10mM DMSO","FDA,EMA","USP40-NF35,IP2010,JP16",208610,"Infection","Anti-infection","Immunology & Inflammation","Delafloxacin (ABT-492, RX-3341, WQ-3034) is a new fluoroquinolone against 155 aerobic and 171 anaerobic pathogens.",440.76,"189279-58-1, 339591-82-1 (sodium salt)",88,199.66,"<1",0,"http://www.selleck.cn/products/ABT-492.html","C18H12ClF3N4O4","free base","RX-3341J, WQ-3034","NC1=C(F)C=C(F)C(=N1)N2C=C(C(O)=O)C(=O)C3=CC(=C(N4CC(O)C4)C(=C23)Cl)F",2.682,3,2,3]
["S1565","Lumacaftor (VX-809)","f7","L1300-03","in 10mM DMSO","FDA,EMA,NDC",null,"206038,211358","Others","CFTR","Transmembrane Transporters","Lumacaftor (VX-809, VRT 826809) acts to correct CFTR mutations common in cystic fibrosis by increasing mutant CFTR (F508del-CFTR) maturation,EC50 of 0.1 μM in fisher rat thyroid cells. Phase 3.",452.41,"936727-05-8",90,198.93,"<1",0,"http://selleckchem.com/products/VX-809.html","C24H18F2N2O5","free base","VRT 826809","CC1=C(N=C(NC(=O)C2(CC2)C3=CC4=C(OC(F)(F)O4)C=C3)C=C1)C5=CC=CC(=C5)C(O)=O",6.411,5,1,5]
["S1567","Pomalidomide (CC-4047)","g7","L1300-03","in 10mM DMSO","FDA,EMA,NDC,PMDA",null,"204026","Angiology/Cancer","Apoptosis related,E3 Ligase ,E3 ligase Ligand,TNF-alpha","Ubiquitin","Pomalidomide (CC-4047) inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs. Pomalidomide can be utilized in PROTAC as a ligand for targeting E3 ligase and inhibiting the E3 ligase protein cereblon (CRBN). Pomalidomide promotes apoptosis and cell cycle arrest.",273.24,"19171-19-8",54,197.63,"<1",0,"http://selleckchem.com/products/Pomalidomide(CC-4047).html","C13H11N3O4","free base","CC-4047","NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1",-0.65,4,2,1]
["S1569","Tazarotene","h7","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia","208258,208662,211175","Inflammation","Retinoid Receptor","Metabolism","Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin.",351.46,"118292-40-3",10,28.45,"<1",0,"http://selleckchem.com/products/Tazarotene(Avage).html","C21H21NO2S","free base","AGN190168","CCOC(=O)C1=CN=C(C=C1)C#CC2=CC3=C(SCCC3(C)C)C=C2",4.951,3,0,5]
["S1573","Fasudil (HA-1077) HCl","a8","L1300-03","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Autophagy,Calcium Channel,MLCK,PKA,PKC,PKG,Rho,ROCK","Cell Cycle","Fasudil (HA-1077, AT-877), a potent and selective inhibitor of Rho kinase, displays less potent inhibiton over PKA, PKG, PKC and MLCK with Ki of 1.6, 1.6, 3.3, and 36 μM in cell-free assays, respectively. Fasudil is also a calcium channel blocker.",327.83,"105628-07-7",5,15.25,65,198.27,"http://selleckchem.com/products/Fasudil-HCl(HA-1077).html","C14H17N3O2S.HCl","Hydrochloride","AT-877,HA-1077 HCl","Cl.O=[S](=O)(N1CCCNCC1)C2=C3C=CN=CC3=CC=C2",0.57,3,1,2]
["S1576","Sulfasalazine (NSC 667219)","b8","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37 ;EP9.2;BP2019;KP Ⅹ;Ph.Int_6th;Martindale:The Extra Pharmacopoeia","040349,075339,080197,084964,085828,086184,087197,088052,089339,089590","Infection/Inflammation","Apoptosis related,Autophagy,COX,Ferroptosis,Immunology & Inflammation related,NF-κB,TGF-beta/Smad","Immunology & Inflammation","Sulfasalazine (NSC 667219, Azulfidine, Salazopyrin, Sulphasalazine) is a sulfa derivative of mesalazine, used as an anti-inflammatory agent to treat bowel disease and rheumatoid arthritis. Sulfasalazine is a potent and specific inhibitor of nuclear factor kappa B (NF-κB), TGF-β and COX-2. Sulfasalazine induces ferroptosis, apoptosis and autophagy.",398.39,"599-79-1",80,200.81,"<1",0,"http://selleckchem.com/products/Sulfasalazine(Azulfidine).html","C18H14N4O5S","free base","Azulfidine, Salazopyrin, Sulphasalazine, NSC 667219","OC(=O)C1=C(O)C=CC(=C1)N=NC2=CC=C(C=C2)[S](=O)(=O)NC3=CC=CC=N3",3.463,6,2,6]
["S1578","Candesartan (CV-11974)","c8","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","078702,091390,202079,203813,209119,210302","Cardiovascular Disease","Angiotensin Receptor","GPCR & G Protein","Candesartan (CV-11974) is an angiotensin II receptor antagonist with IC50 of 0.26 nM.",440.45,"139481-59-7",88,199.8,"<1",0,"http://selleckchem.com/products/Candesartan(Atacand).html","C24H20N6O3","free base","CV-11974","CCOC1=NC2=C([N]1CC3=CC=C(C=C3)C4=CC=CC=C4C5=N[NH]N=N5)C(=CC=C2)C(O)=O",4.626,6,1,7]
["S1591","Bestatin (NK421)","d8","L1300-03","in 10mM DMSO","CFDA, PMDA","Martindale the Extra Pharmacopoei, JP17",null,"Others","Immunology & Inflammation related","Immunology & Inflammation","Bestatin (Ubenimex,NK421) is a potent aminopeptidase-B and leukotriene (LT) A4 hydrolase inhibitor, used in the treatment of acute myelocytic leukemia.",308.37,"58970-76-6",4,12.97,"<1",0,"http://www.selleck.cn/products/Ubenimex(Bestatin).html","C16H24N2O4","Free Base","Ubenimex,NK421","CC(C)CC(NC(=O)C(O)C(N)CC1=CC=CC=C1)C(O)=O",-1.34,2,3,8]
["S1593","Apixaban (BMS 562247-01)","e8","L1300-03","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA",null,"209845,209944,210013,210026,210119,210156","Cardiovascular Disease","Factor Xa","Metabolism","Apixaban (BMS 562247-01) is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively.",459.5,"503612-47-3",18,39.17,"<1",0,"http://selleckchem.com/products/Apixaban(BMS-562247-01).html","C25H25N5O4","free base","BMS 562247-01","COC1=CC=C(C=C1)[N]2N=C(C(N)=O)C3=C2C(=O)N(CC3)C4=CC=C(C=C4)N5CCCCC5=O",2.865,5,1,5]
["S1601","Reserpine","f8","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","009627,009663,009667,009838,009859,010441,011185,080393,080446,080457,080492,080525,080582,080637,080679,080721,080723,080749,080753,080975,083058,083145,084663,084974,085207,085401,085775,086117,089019,089020","Cardiovascular Disease/Neurological Disease","VMAT","Transmembrane Transporters","Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug. Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).",608.68,"50-55-5",13,21.36,"<1",0,"http://selleckchem.com/products/Reserpine.html","C33H40N2O9","free base","N/A","COC1C(CC2CN3CCC4=C([NH]C5=C4C=CC(=C5)OC)C3CC2C1C(=O)OC)OC(=O)C6=CC(=C(OC)C(=C6)OC)OC",4.242,9,1,10]
["S1603","Furosemide (NSC 269420)","g8","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.4;KP Ⅹ;BP2019;Ph.Int_6th;JP17;IP2010","018025,018267,018369,018370,018413,018415,018419,018420,018487,018507,018569,018579,018667,018670,018750,018753,018790,018823,018868,018902,019036,070014,070017,070019,070023,070043,070078,070082,070086,070095,070096,070100,070412,070413,070433,070434,070449,070450,070528,070578,070604,070655,071379,071439,071594,072080,074017,074337,075241,076796,077293,077941,078010,091258,202747,203428,207552,212174","Cardiovascular Disease/Metabolic Disease","NKCC","Transmembrane Transporters","Furosemide (NSC 269420) is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used in the treatment of congestive heart failure and edema.",330.74,"54-31-9",66,199.55,"<1",0,"http://selleckchem.com/products/Furosemide(Lasix).html","C12H11ClN2O5S","free base","NSC 269420","N[S](=O)(=O)C1=C(Cl)C=C(NCC2=CC=CO2)C(=C1)C(O)=O",1.403,4,2,5]
["S1604","Olmesartan Medoxomil","h8","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","078276,090237,091079,202375,203012,203281,204798,204814,205192,205482,206631,206763,207480,207662,208130,210552,211049","Cardiovascular Disease","Angiotensin Receptor","GPCR & G Protein","Olmesartan Medoxomil (CS-866,RNH-6270) is a selective angiotensin II type 1 (AT(1)) receptor antagonist, used in the treatment of high blood pressure.",558.59,"144689-63-4",89,159.33,"<1",0,"http://selleckchem.com/products/olmesartan-medoxomil-Benicar.html","C29H30N6O6","free base","CS-866,RNH-6270","CCCC1=NC(=C([N]1CC2=CC=C(C=C2)C3=CC=CC=C3C4=N[NH]N=N4)C(=O)OCC5=C(C)OC(=O)O5)C(C)(C)O",4.814,9,1,11]
["S1605","Cefdinir","a9","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","065259,065264,065330,065332,065337,065368,065418,065429,065434,065473","Infection","Antibiotics,Bacterial","Microbiology","Cefdinir (FK 482, PD 134393, CI-983) is an oral cephalosporin antibiotic, used to treat bacterial infections in many different parts of the body.",395.41,"91832-40-5",79,199.79,"<1",0,"http://selleckchem.com/products/Cefdinir(Omnicef).html","C14H13N5O5S2","free base","FK 482, PD 134393, CI-983","NC1=NC(=CS1)C(=N/O)/C(=O)NC2C3SCC(=C(N3C2=O)C(O)=O)C=C",-0.172,5,2,5]
["S1606","Clotrimazole","b9","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","072640,072641,073306,074165,074580,076387,076763,078338,090219,209815","Infection","Antineoplastic and Immunosuppressive Antibiotics,Fungal","Microbiology","Clotrimazole (BAY b 5097, FB 5097) alters the permeability of the fungal cell wall by inhibiting the biosynthesis of ergosterol, used in the treatment of fungal infections.",344.84,"23593-75-1",11,31.9,"<1",0,"http://selleckchem.com/products/Clotrimazole(Canesten).html","C22H17ClN2","free base","BAY b 5097, FB 5097","ClC1=C(C=CC=C1)C([N]2C=CN=C2)(C3=CC=CC=C3)C4=CC=CC=C4",5.222,1,0,4]
["S1607","Rizatriptan Benzoate","c9","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","077263,077526,078173,078739,079230,200482,201914,201967,201993,202047,202244,202477,202490,203062,203146,203147,203252,203269,203334,203478,204090,204339,204722,207835,207836","Neurological Disease","5-HT Receptor","Neuronal Signaling","Rizatriptan Benzoate (MK-462) is an agonist at serotonin 5-HT1B and 5-HT1D receptors, used to treat acute migraine attacks.",391.47,"145202-66-0",20,51.09,46,117.51,"http://selleckchem.com/products/Rizatriptan-Benzoate(Maxalt).html","C22H25N5O2","Benzoate","MK-462 Benzoate","CN(C)CCC1=C[NH]C2=C1C=C(C[N]3C=NC=N3)C=C2.OC(=O)C4=CC=CC=C4",0.492,3,1,6]
["S1608","Pyridostigmine Bromide","d9","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","020414,040457,040502,040512,089572,203184,204737,205464,205650,211181,211694","Neurological Disease","AChR","Neuronal Signaling","Pyridostigmine Bromide is a parasympathomimetic and a reversible cholinesterase inhibitor.",261.12,"101-26-8",52,199.14,52,199.14,"http://selleckchem.com/products/Pyridostigmine-Bromide(Mestinon).html","C9H13BrN2O2","Bromide","N/A","[Br-].CN(C)C(=O)OC1=C[N+](=CC=C1)C",-1.014,2,0,2]
["S1609","Methimazole","e9","L1300-03","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;BP2019;IP2010","040350,040411,040547,040619,040734,040870,202068","Endocrinology/Metabolic Disease","Others","Others","Methimazole (Tapazole, Thiamazole) is an antithyroid medicine.",114.17,"60-56-0",23,201.45,23,201.45,"http://selleckchem.com/products/Methimazole(Tapazole).html","C4H6N2S","free base","Tapazole, Thiamazole","CN1C=CNC1=S",0.414,0,1,0]
["S1610","Metolazone","f9","L1300-03","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","075543,076466,076482,076600,076698,076732,076833,076891","Cardiovascular Disease","Others","Others","Metolazone (SR 720-22) is a diuretic that primarily used to treat congestive heart failure and high blood pressure.",365.83,"17560-51-9",73,199.55,"<1",0,"http://selleckchem.com/products/Metolazone(Zaroxolyn).html","C16H16ClN3O3S","free base","SR 720-22","CC1NC2=CC(=C(C=C2C(=O)N1C3=CC=CC=C3C)[S](N)(=O)=O)Cl",2.463,3,2,2]
["S1611","Cefoperazone","g9","L1300-03","in 10mM DMSO","FDA,DMF,CFDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","050551,063333","Infection","Antibiotics","Microbiology","Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM.",645.67,"62893-19-0",100,154.88,"<1",0,"http://selleckchem.com/products/cefoperazone-cefobid.html","C25H27N9O8S2","free base","N/A","CCN1CCN(C(=O)NC(C(=O)NC2C3SCC(=C(N3C2=O)C(O)=O)CSC4=NN=N[N]4C)C5=CC=C(O)C=C5)C(=O)C1=O",-0.792,9,3,9]
["S1613","Silodosin","h9","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","JP17;Martindale:The Extra Pharmacopoeia","204726,206541,209745,210626,210687,211060,211166","Others","Adrenergic Receptor","Neuronal Signaling","Silodosin (KAD 3213, KMD 3213) is a highly selective α1A-adrenoceptor antagonist, used in treatment of benign prostatic hyperplasia.",495.53,"160970-54-7",99,199.79,"<1",0,"http://selleckchem.com/products/Silodosin(Rapaflo).html","C25H32F3N3O4","free base","KAD 3213, KMD 3213","CC(CC1=CC2=C(N(CCCO)CC2)C(=C1)C(N)=O)NCCOC3=CC=CC=C3OCC(F)(F)F",3.451,3,3,14]
["S1614","Riluzole (PK 26124)","a10","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","076173,091300,091394,091417,203042,204048,204430","Neurological Disease","GluR,Sodium Channel","Transmembrane Transporters","Riluzole (PK 26124, RP-54274) is a glutamate release inhibitor with neuroprotective, anticonvulsant, anxiolytic and anesthetic qualities.",234.2,"1744-22-5",46,196.41,"<1",0,"http://selleckchem.com/products/Riluzole(Rilutek).html","C8H5F3N2OS","free base","RP-54274, PK 26124","NC1=NC2=C(S1)C=C(OC(F)(F)F)C=C2",3.828,2,1,2]
["S1618","Sulfameter","b10","L1300-03","in 10mM DMSO","FDA",null,"016000","Infection","Bacterial","Immunology & Inflammation","Sulfameter  is a long-acting sulfonamide antibacterial.",280.3,"651-06-9",56,199.79,"<1",0,"http://selleckchem.com/products/Sulfameter(Bayrena).html","C11H12N4O3S","free base","N/A","COC1=CN=C(N[S](=O)(=O)C2=CC=C(N)C=C2)N=C1",0.297,5,2,4]
["S1619","Prilocaine","c10","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;EP9.4;BP2019;Martindale:The Extra Pharmacopoeia","079235","Neurological Disease","Sodium Channel","Transmembrane Transporters","Prilocaine (NSC 40027) is a local anesthetic of the amino amide type. It acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation.",220.31,"721-50-6",44,199.72,"<1",0,"http://selleckchem.com/products/Prilocaine.html","C13H20N2O","free base","NSC 40027","CCCNC(C)C(=O)NC1=C(C)C=CC=C1",2.263,1,2,5]
["S1620","Darunavir Ethanolate","d10","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","Martindale:The Extra Pharmacopoeia","202073,202083,202118,202118,207189","Infection","COVID-19,HIV Protease","Proteases","Darunavir Ethanolate (TMC-114, UIC 94017) is a nonpeptidic HIV protease inhibitor, used to treat HIV infection.",593.73,"635728-49-3",100,168.43,"<1",0,"http://selleckchem.com/products/Darunavir-Ethanolate(Prezista).html","C27H37N3O7S.C2H5OH","Ethanolate","TMC-114, UIC 94017","CCO.CC(C)CN(CC(O)C(CC1=CC=CC=C1)NC(=O)OC2COC3OCCC23)[S](=O)(=O)C4=CC=C(N)C=C4",2.622,6,4,12]
["S1622","Prednisone (NSC-10023)","e10","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;EP9.3;BP2019;IP2010;Martindale:The Extra Pharmacopoeia","017109,040256,040362,040392,040538,040581,040584,040611,040890,080209,080232,080237,080279,080283,080292,080300,080301,080306,080320,080321,080328,080334,080336,080343,080350,080352,080353,080356,080359,080371,080397,080491,080506,080514,080563,080701,080782,083059,083676,083677,083807,084122,084133,084134,084236,084275,084283,084341,084417,084440,084634,084662,084774,084913,085084,085115,085151,085161,085162,085543,085811,085813,086061,086062,086595,086596,086813,086867,086946,086968,087342,087470,087471,087682,087701,087772,087773,087800,087801,087833,087984,087985,087986,088394,088395,088396,088465,088703,088832,088865,088866,088867,089028,089247,089387,089388,089389,089597,089598,089599,089726,089983,089984,204867,210525,211495,211496","Cancer/Hematology/Immunology/Inflammation","Glucocorticoid Receptor,Immunology & Inflammation related","Endocrinology & Hormones","Prednisone (NSC-10023, Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.",358.43,"53-03-2",71,198.09,"<1",0,"http://selleckchem.com/products/Prednisone.html","C21H26O5","free base","Adasone,NSC-10023","CC12CC(=O)C3C(CCC4=CC(=O)C=CC34C)C1CCC2(O)C(=O)CO",1.217,3,1,2]
["S1625","Ethinyl Estradiol","f10","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010","077182","Cancer/Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Ethinyl Estradiol is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills.",296.4,"57-63-6",59,199.06,"<1",0,"http://selleckchem.com/products/Ethinyl-Estradiol.html","C20H24O2","free base","N/A","CC12CCC3C(CCC4=CC(=CC=C34)O)C1CCC2(O)C#C",4.886,0,1,0]
["S1626","Naproxen Sodium","g10","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","021920,074106,074142,074162,074195,074198,074230,074242,074257,074289,074319,074367,074455,074480,074495,074635,074646,074661,074789,075168,075416,076544,078314,078432,078486,079096,090545,091183,091353,200629,202807,204872,205497,207612,208363","Inflammation","COX","Neuronal Signaling","Naproxen Sodium (RS-3650) is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively.",252.24,"26159-34-2",3,11.89,50,198.22,"http://selleckchem.com/products/Naproxen-Sodium(Aleve).html","C14H13NaO3","Sodium Salt","RS-3650","[Na+].COC1=CC=C2C=C(C=CC2=C1)C(C)C([O-])=O",1.375,1,0,3]
["S1627","Nitazoxanide (NSC 697855)","h10","L1300-03","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","021497,021498,021818","Infection","Autophagy,Influenza Virus,mTOR,Serotonin Transporter","Microbiology","Nitazoxanide (NTZ, NSC 697855) is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent(IC50 for canine influenza virus ranges from 0.17 to 0.21 μM). Nitazoxanide modulates autophagy and inhibits mTORC1 signaling.",307.28,"55981-09-4",62,201.77,"<1",0,"http://selleckchem.com/products/Nitazoxanide(Alinia).html","C12H9N3O5S","free base","NTZ, NSC 697855","CC(=O)OC1=C(C=CC=C1)C(=O)NC2=NC=C(S2)[N+]([O-])=O",1.398,4,1,5]
["S1628","Triamcinolone Acetonide","a11","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP41-NF36;BP2018;EP9.2;IP2010;JP17;Martindale:The Extra Pharmacopoeia","011601,019503,040037,040038,040039,040040,040374,040386,040467,040671,040672,040771,070730,078104,085691,085692,085825,086275,086276,086277,086413,086414,087191,087192,087385,087797,087798,087799,087902,087912,087921,087922,087932,087990,087991,087992,088090,088091,088092,088094,088095,088096,088450,088451,088690,088692,089129,089274,089275,089276,089795,089796,089797,089798,089913,090164,090166,202374,204606,204608,205373,205592,205782,206312,206379,206786,207094,207117,207365,207550,207651,208320,208590,208763,208848,208925,209535,209852,210346","Infection/Inflammation","Glucocorticoid Receptor","Metabolism","Triamcinolone acetonide is a synthetic glucocorticoid, used in the symptomatic treatment of inflammation.",434.5,"76-25-5",87,200.23,"<1",0,"http://selleckchem.com/products/Triamcinolone-Acetonide.html","C24H31FO6","free base","N/A","CC1(C)OC2CC3C4CCC5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(O1)C(=O)CO",1.157,4,2,2]
["S1629","Orlistat (Ro 18-0647)","b11","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","021887,020766","Metabolic Disease","Apoptosis related,Fatty Acid Synthase,Lipase","Metabolism","Orlistat (Ro 18-0647, Tetrahydrolipstatin) is a general lipase inhibitor with IC50 of 122 ng/ml for PL from human duodenal juice. Orlistat treatment reduces proliferation, induces apoptosis and arrests cell cycle.",495.73,"96829-58-2",99,199.71,"<1",0,"http://selleckchem.com/products/Orlistat(Alli).html","C29H53NO5","free base","Tetrahydrolipstatin,Ro 18-0647","CCCCCCCCCCCC(CC1OC(=O)C1CCCCCC)OC(=O)C(CC(C)C)NC=O",8.333,5,1,23]
["S1630","Allopurinol","c11","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","018241,018659,018785,018832,018877,070147,070150,070268,070269,070466,070467,070579,070580,070950,070951,071450,075798,077353,078253,078390,090637,203154,204467,210117,211820","Inflammation/Metabolic Disease","ROS","Immunology & Inflammation","Allopurinol is a purine analog inhibitor of the enzyme xanthine oxidase, used to treat gout or kidney stones, and to decrease levels of uric acid.",136.11,"315-30-0",27,198.37,4,29.39,"http://selleckchem.com/products/Allopurinol(Zyloprim).html","C5H4N4O","Free Base","N/A","O=C1N=CN=C2NNC=C12",-2.125,3,2,0]
["S1631","Allopurinol Sodium","d11","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","076870","Inflammation/Metabolic Disease","ROS","Immunology & Inflammation","Allopurinol Sodium  is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.",159.1,"17795-21-0",32,201.13,32,201.13,"http://selleckchem.com/products/Allopurinol-Sodium(Aloprim).html","C5H4N4NaO","Sodium Salt","N/A","[Na+].O=C1NC=NC2=C1C=N[NH]2",-0.681,3,2,0]
["S1633","Zafirlukast (ICI-204219)","e11","L1300-03","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia","090372","Inflammation","LTR","Immunology & Inflammation","Zafirlukast (ICI-204219) is an oral leukotriene receptor antagonist (LTRA), used to prevent asthma symptoms.",575.68,"107753-78-6",100,173.71,"<1",0,"http://selleckchem.com/products/Zafirlukast(Accolate).html","C31H33N3O6S","free base","ICI-204219","COC1=CC(=CC=C1CC2=C[N](C)C3=C2C=C(NC(=O)OC4CCCC4)C=C3)C(=O)N[S](=O)(=O)C5=CC=CC=C5C",6.299,6,2,9]
["S1635","Erythromycin","f11","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP38-NF33;BP2013;JP16;IP2010;Martindale:The Extra Pharmacopoeia","050532,062563,050610,061621,062326,062327,062328,062342,062446,062447,062481,062485,062616,062746,062825,062957,063038,063098,063211,064030,064039,064067,064126,064127,064128,064184,064187,065320,090215,208100,208154,209720","Infection","Antibiotics,Antibiotics for Mammalian Cell Culture","Microbiology","Erythromycin (E-Mycin) is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin (IC50=1.5 μg/ml).",733.93,"114-07-8",147,200.29,3,4.09,"http://selleckchem.com/products/Erythromycin(E-Mycin).html","C37H67NO13","Free Base","E-Mycin","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)C(=O)C(C)C(O)C1(C)O",1.792,8,3,7]
["S1636","Amphotericin B","g11","L1300-03","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;KP Ⅹ ;BP2015;EP9.2;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia;","062728,063206,064062,064141","Infection","Antibiotics,Antibiotics for Mammalian Cell Culture","Microbiology","Amphotericin B (AMB, NSC 527017) is an amphipathic polyene antibiotic which permeabilizes ergosterol-containing membranes.",924.08,"1397-89-3",22,23.81,"<1",0,"http://selleckchem.com/products/Amphotericin-B(Abelcet).html","C47H73NO17","free base","NSC 527017","CC1OC(OC/2CC3OC(O)(CC(O)CC(O)C(O)CCC(O)CC(O)CC(=O)OC(C)C(C)C(O)C(C)\\C=C\\C=C\\C=C\\C=C\\C=C\\C=C\\C=C2)CC(O)C3C(O)=O)C(O)C(N)C1O",-2.617,6,10,3]
["S1638","Ibuprofen (NSC 256857)","h11","L1300-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.6;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","070038,070041,070045,070057,070079,070080,070081,070328,070329,070330,070435,070436,070437,070476,070481,070493,070556,070629,070630,070709,070733,070736,070818,070908,070985,070986,071027,071028,071029,071030,071122,071123,071124,071125,071144,071145,071146,071154,071163,071229,071230,071231,071232,071264,071265,071266,071267,071268,071333,071334,071335,071338,071448,071462,071547,071575,071639,071644,071664,071666,071667,071668,071735,071765,071769,071807,071870,071905,071911,071935,071938,071964,071999,072004,072040,072064,072065,072096,072098,072137,072169,072199,072249,072299,072300,072901,072903,073019,073141,073343,073344,073345,073691,074525,074533,074782,074916,074931,074978,075010,075139,075217,075661,075682,075995,076112,076117,076359,076460,076741,076925,077114,077338,077349,078132,078329,078558,078682,079058,079129,079174,079205,079233,090796,091237,091239,091355,091625,200457,202300,202312,202413,203599,204062,204469,205647,206568,206989,206990,206999,207052,207095,207753,208865,209178,209179,209204,209207,210149,210602,210755","Neurological Disease/Inflammation","COX","Neuronal Signaling","Ibuprofen (NSC 256857, Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively.",206.28,"15687-27-1",41,198.76,"<1",0,"http://selleckchem.com/products/Ibuprofen(Advil).html","C13H18O2","free base","Dolgesic,NSC 256857","CC(C)CC1=CC=C(C=C1)C(C)C(O)=O",3.607,1,0,4]
["S1639","Amprenavir (VX-478)","a2","L1300-04","in 10mM DMSO","FDA,DMF,EMA","Martindale:The Extra Pharmacopoeia","021007,021039","Infection","HIV Protease","Proteases","Amprenavir (VX-478, 141W94, KVX-478) is a potent PXR-selective agonist, and an HIV protease inhibitor, used to treat HIV.",505.63,"161814-49-9",16,31.64,"<1",0,"http://selleckchem.com/products/Amprenavir-(Agenerase).html","C25H35N3O6S","free base","141W94, VX-478, KVX-478","CC(C)CN(CC(O)C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)[S](=O)(=O)C3=CC=C(N)C=C3",2.429,5,3,12]
["S1640","Albendazole (SKF-62979)","b2","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.6;KP Ⅹ;BP2018;Ph.Int_6th;Martindale:The Extra Pharmacopoeia","208094,208979,210011,210434,211117","Parasite","ADC Cytotoxin,Microtubule Associated","Cytoskeletal Signaling","Albendazole (SKF-62979) is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.",265.33,"54965-21-8",17,64.07,"<1",0,"http://selleckchem.com/products/Albendazole(Albenza).html","C12H15N3O2S","free base","SKF-62979","CCCSC1=CC=C2N=C(NC(=O)OC)[NH]C2=C1",3.065,3,2,5]
["S1641","Chlorothiazide","c2","L1300-04","in 10mM DMSO","FDA,DMF,NDC","USP39-NF34;BP2015;IP2010;Martindale:The Extra Pharmacopoeia","084026,084217,085165,085173,085485,085569,086028,086795,086796,086938,086940,087736","Cardiovascular Disease/Metabolic Disease","Others","Others","Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM)",295.72,"58-94-6",59,199.51,"<1",0,"http://selleckchem.com/products/Chlorothiazide(Diuril).html","C7H6ClN3O4S2","free base","N/A","N[S](=O)(=O)C1=C(Cl)C=C2N=CN[S](=O)(=O)C2=C1",-0.177,5,2,1]
["S1643","Ursodiol","d2","L1300-04","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","075517,075592,077895,079082,079184,090530,090801,200826,202540,210707,211145,211301","Gastroenterology","FXR","GPCR & G Protein","Ursodiol (Ursodeoxycholic acid, UDCA) reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones. (IC50=0.22 μM)",392.57,"128-13-2",79,201.24,"<1",0,"http://selleckchem.com/products/Ursodiol(Actigal).html","C24H40O4","free base","Ursodeoxycholic acid, UDCA","CC(CCC(O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C",4.014,1,2,4]
["S1644","Nitrofural","e2","L1300-04","in 10mM DMSO","CFDA","EP9.2",null,"Infection","Anti-infection","Microbiology","Nitrofural (Nitrofurazone) is a topical anti-infective agent with an IC50 of 22.83 ± 1.2 μM. (Rat LD50 = 590 mg/kg)",198.14,"59-87-0",40,201.88,"<1",0,"http://selleckchem.com/products/Nitrofurazone(ACTIN-N).html","C6H6N4O4","free base","Nitrofurazone","NC(=O)N/N=C/C1=CC=C(O1)[N+]([O-])=O",0.223,3,2,3]
["S1645","Ketoprofen","f2","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","073515,073516,073517,074014,074024,074035,074879,075270,075364,075679","Neurological Disease/Inflammation","COX","Neuronal Signaling","Ketoprofen (RP-19583) is a dual COX1/2 inhibitor, used as a nonsteroidal anti-inflammatory drug to treat arthritis-related inflammatory pains.",254.28,"22071-15-4",51,200.57,"<1",0,"http://selleckchem.com/products/Ketoprofen(Actron).html","C16H14O3","free base","RP-19583","CC(C(O)=O)C1=CC(=CC=C1)C(=O)C2=CC=CC=C2",3.361,2,0,4]
["S1646","Ketorolac","g2","L1300-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;KP Ⅹ;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","074754,074761,074790,074801,074802,074955,074993,075222,075228,075230,075284,075299,075348,075626,075631,075772,075784,076109,076209,076271,076583,076722,077201,077308,077942,077943,078145,078299,078399,078434,078721,078737,090017,091065,201155,203242,203376,203410,204216,205191,209900,210616","Neurological Disease/Inflammation","COX","Neuronal Signaling","Ketorolac is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively.",255.27,"74103-06-3",75,293.81,"<1",0,"http://selleckchem.com/products/Ketorolac-Tromethamine(Toradol).html","C15H13N1O3","free base","N/A","OC(=O)C1CC[N]2C1=CC=C2C(=O)C3=CC=CC=C3",2.832,2,0,3]
["S1647","Adenosine","h2","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Martindale:The Extra Pharmacopoeia","076404,076500,076501,076564,077133,077283,077425,077897,078076,078618,078640,078676,078686,079147,090010,090212,090220,090450,202313,203883,205331,205568,206778","Cardiovascular Disease","Adenosine Receptor,Nucleoside Analog/Antimetabolite","GPCR & G Protein","Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond.",267.24,"58-61-7",12,44.9,"<1",0,"http://selleckchem.com/products/Adenosine(Adenocard).html","C10H13N5O4","free base","N/A","NC1=NC=NC2=C1N=C[N]2C3OC(CO)C(O)C3O",-1.881,4,4,2]
["S1649","Zolmitriptan","a3","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37 ;EP9.5;Martindale:The Extra Pharmacopoeia","090861,201779,202078,202279,202476,202560,202890,202956,203019,203186,203476,203772,204041,204232,204284,204336,205074,206973,207021,207867","Neurological Disease","5-HT Receptor","Neuronal Signaling","Zolmitriptan(BW-311C90) is a novel and highly selective 5-HT(1B/1D) receptor agonist, used in the treatment of acute migraines.",287.36,"139264-17-8",58,201.84,"<1",0,"http://selleckchem.com/products/Zolmitriptan(Zomig).html","C16H21N3O2","free base","BW-311C90","CN(C)CCC1=C[NH]C2=C1C=C(CC3COC(=O)N3)C=C2",2.457,2,2,5]
["S1651","Telbivudine","b3","L1300-04","in 10mM DMSO","FDA,DMF,EMA,CFDA","Martindale:The Extra Pharmacopoeia","022011,022154","Infection","Reverse Transcriptase","Microbiology","Telbivudine(NV 02B) is a potent, and selective HBV reverse transcriptase inhibitor, used to treat HBV infection.",242.23,"3424-98-4",48,198.16,48,198.16,"http://selleckchem.com/products/Telbivudine(Sebivo).html","C10H14N2O5","free base","NV 02B","CC1=CN(C2CC(O)C(CO)O2)C(=O)NC1=O",-1.238,3,3,2]
["S1652","Monobenzone","c3","L1300-04","in 10mM DMSO","FDA,DMF","USP42-NF37;Martindale:The Extra Pharmacopoeia","008173","Others","Tyrosinase","Proteases","Monobenzone(Benoquin) is a compound used as a topical agent for medical depigmentation. It can specifically block tyrosinase.",200.23,"103-16-2",40,199.77,"<1",0,"http://selleckchem.com/products/Monobenzone(Benoquin).html","C13H12O2","free base","Benoquin","OC1=CC=C(OCC2=CC=CC=C2)C=C1",3.155,1,1,3]
["S1653","Tretinoin (NSC 122758)","d3","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.2;BP2017;Martindale:The Extra Pharmacopoeia","074873,075213,075260,075264,075265,075529,075589,076498,077684,090098,201687,202026,202209,202567,207955,208279,211644,211645","Others","Retinoid Receptor","Metabolism","Tretinoin (Retinoic acid, All-trans Retinoic Acid, ATRA, Vitamin A acid, Vesanoid, Airol, Renova, Atralin, Retin-A, Avita, Stieva-A,NSC 122758), which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.",300.4,"302-79-4",60,199.73,"<1",0,"http://selleckchem.com/products/Tretinoin(Aberela).html","C20H28O2","free base","Retinoic acid, All-trans Retinoic Acid, ATRA, Vitamin A acid, Vesanoid, Airol, Renova, Atralin, Retin-A, Avita, Stieva-A,NSC 122758","CC1=C(\\C=C\\C(C)=C\\C=C\\C(C)=C\\C(O)=O)C(C)(C)CCC1",5.551,1,0,5]
["S1654","Phenylbutazone","e3","L1300-04","in 10mM DMSO","FDA,DMF,CFDA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","084339,086151,087674,087756,087774,088218,088863,088994","Inflammation/Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Phenylbutazone (Butazolidine) is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis.",308.37,"50-33-9",62,201.06,"<1",0,"http://selleckchem.com/products/Phenylbutazone(Butazolidin).html","C19H20N2O2","free base","Butazolidine","CCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3",3.954,2,0,5]
["S1655","Ezetimibe (SCH-58235)","f3","L1300-04","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","078560,078724,200831,201790,203931,204331,207311,208332,208803,209234,209838,211550","Metabolic Disease","LDL","Metabolism","Ezetimibe (SCH-58235) is a potent, selective, cholesterol absorption inhibitor, used to lower cholesterol.",409.4,"163222-33-1",81,197.85,"<1",0,"http://selleckchem.com/products/Ezetimibe(Zetia).html","C24H21F2NO3","free base","SCH-58235","OC(CCC1C(N(C1=O)C2=CC=C(F)C=C2)C3=CC=C(O)C=C3)C4=CC=C(F)C=C4",4.633,1,2,6]
["S1657","Enalaprilat Dihydrate","g3","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","075456,075458,075571,075578,075634,078687","Cardiovascular Disease/Endocrinology/Metabolic Disease","RAAS","Endocrinology & Hormones","Enalaprilat (MK-422) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.",348.4,"84680-54-6",70,200.92,"<1",0,"http://selleckchem.com/products/Enalaprilat.html","C18H24N2O5.2H2O","Dihydrate","MK-422 Dihydrate","O.O.CC(NC(CCC1=CC=CC=C1)C(O)=O)C(=O)N2CCCC2C(O)=O",-1.53,3,1,8]
["S1658","Dofetilide","h3","L1300-04","in 10mM DMSO","FDA,DMF,EMA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","207058,207746,208519,208625,210466","Cardiovascular Disease","Potassium Channel","Transmembrane Transporters","Dofetilide (UK-68798) is a selective potassium channel ((hERG)) blocker, used as a Class III antiarrhythmic drug.",441.56,"115256-11-6",88,199.29,"<1",0,"http://selleckchem.com/products/Dofetilide(Tikosyn).html","C19H27N3O5S2","free base","UK-68798","CN(CCOC1=CC=C(N[S](C)(=O)=O)C=C1)CCC2=CC=C(N[S](C)(=O)=O)C=C2",1.679,5,2,11]
["S1662","Isradipine","a4","L1300-04","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Martindale:The Extra Pharmacopoeia","077169,077317,201067","Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Isradipine (PN 200-110) is a potent and selective L-type voltage-gated calcium channel blocker, used to treat high blood pressure.",371.39,"75695-93-1",74,199.25,"<1",0,"http://selleckchem.com/products/Isradipine(Dynacirc).html","C19H21N3O5","free base","PN 200-110","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC3=NON=C23)C(=O)OC(C)C)C",2.168,7,1,6]
["S1665","Estrone","b4","L1300-04","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","083397,085239","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estrone is an estrogenic hormone.",270.37,"53-16-7",54,199.73,"<1",0,"http://selleckchem.com/products/Estrone.html","C18H22O2","free base","N/A","CC12CCC3C(CCC4=CC(=CC=C34)O)C1CCC2=O",3.938,1,1,0]
["S1666","Flucytosine","c4","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;Ph.Int_6th;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","201566,204652,206550,207536","Infection","Fungal","Microbiology","Flucytosine (5-Fluorocytosine, 5-FC, NSC 103805, Ro 2-9915) is an antifungal drug with IC50 of 0.93 μM in C. albicans.",129.09,"2022-85-7",8,61.97,5,38.73,"http://selleckchem.com/products/Flucytosine(Ancobon).html","C4H4FN3O","free base","5-Fluorocytosine, 5-FC, NSC 103805, Ro 2-9915","NC1=NC(=O)NC=C1F",-1.048,2,2,0]
["S1667","Trichlormethiazide","d4","L1300-04","in 10mM DMSO","FDA,DMF,PMDA","USP42-NF37;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","083462,083847,083855,083967,085568,085962,086171,086458,087005,087007","Cardiovascular Disease/Metabolic Disease","Others","Others","Trichlormethiazide is a diuretic with properties similar to those of hydrochlorothiazide.",380.66,"133-67-5",54,141.86,"<1",0,"http://selleckchem.com/products/Trichlormethiazide(Achletin).html","C8H8Cl3N3O4S2","free base","N/A","N[S](=O)(=O)C1=C(Cl)C=C2NC(N[S](=O)(=O)C2=C1)C(Cl)Cl",1.046,4,3,2]
["S1669","Loteprednol etabonate","e4","L1300-04","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","207609","Inflammation/Neurological Disease/Ophthalmology","Glucocorticoid Receptor","Endocrinology & Hormones","Loteprednol etabonate is a potent glucocorticoid receptor agonist, used in treatment of inflammation of the eye due to allergies.",466.95,"82034-46-6",93,199.16,"<1",0,"http://selleckchem.com/products/Loteprednol-etabonate.html","C24H31ClO7","free base","N/A","CCOC(=O)OC1(CCC2C3CCC4=CC(=O)C=CC4(C)C3C(O)CC12C)C(=O)OCCl",3.865,6,1,7]
["S1673","Aminophylline","f4","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","081142,084530,084531,084533,084540,084552,084563,084568,084574,084575,084576,084577,084588,084632,084674,084699,085003,085261,085284,085289,085333,085409,085410,085564,085567,086606,087200,087209,087239,087240,087242,087250,087387,087392,087431,087500,087501,087522,087523,087600,087601,087867,087868,087886,088126,088156,088182,088183,088297,088298,088314,088319,088407,088429,088749","Inflammation/Respiratory Disease","PDE","Metabolism","Aminophylline (Phyllocontin) is a competitive nonselective phosphodiesterase inhibitor with an IC50 of 0.12 mM and also a nonselective adenosine receptor antagonist.",420.43,"317-34-0",53,126.06,84,199.8,"http://selleckchem.com/products/Aminophylline(Truphylline).html","C16H24N10O4","Ethylenediamine","Phyllocontin","CN1C(=O)N(C)C2=C([NH]C=N2)C1=O.CN3C(=O)N(C)C4=C([NH]C=N4)C3=O.NCCN",-2.089,6,4,1]
["S1675","Lubiprostone","g4","L1300-04","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia","021908","Gastrointestinal Disease","Chloride Channel","Transmembrane Transporters","Lubiprostone (RU 0211,SPI-0211) is an activator of ClC-2 chloride channels, used in the management of idiopathic chronic constipation.",390.46,"136790-76-6",78,199.76,"<1",0,"http://selleckchem.com/products/Lubiprostone(Amitiza).html","C20H32F2O5","Free Base","RU 0211,SPI-0211","CCCCC(F)(F)C(=O)CCC1C(O)CC(=O)C1CCCCCCC(O)=O",3.831,3,1,14]
["S1676","Amorolfine HCl","h4","L1300-04","in 10mM DMSO","DMF,CFDA,PMDA,HMA","EP9.7;BP2019;Martindale:The Extra Pharmacopoeia",null,"Infection","Fungal","Microbiology","Amorolfine HCl(Ro 14-4767 HCl) is an antifungal reagent.",353.97,"78613-38-4",28,79.1,9,25.43,"http://selleckchem.com/products/Amorolfine-Hydrochloride.html","C21H35NO.HCl","Hydrochloride","Ro 14-4767 HCl","Cl.CCC(C)(C)C1=CC=C(CC(C)CN2CC(C)OC(C)C2)C=C1",5.681,1,0,6]
["S1677","Chloramphenicol","a5","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","JP17;BP2017;Ph.Int_5th;IP2010;Martindale:The Extra Pharmacopoeia","060133,062042,062247,062406,062628","Infection","Antibiotics for Plant Cell Culture,Bacterial,Selection Antibiotics for Transfected Cell","Microbiology","Chloramphenicol (Chloromycetin) is a bacteriostatic by inhibiting protein synthesis.",323.13,"56-75-7",65,201.16,"<1",0,"http://selleckchem.com/products/Chloramphenicol(Chloromycetin).html","C11H12Cl2N2O5","free base","Chloromycetin","OCC(NC(=O)C(Cl)Cl)C(O)C1=CC=C(C=C1)[N+]([O-])=O",1.025,1,3,6]
["S1679","Flurbiprofen","b5","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","074358,074405,074411,074431,074448,074560,074647,075058","Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs).",244.26,"5104-49-4",49,200.61,"<1",0,"http://selleckchem.com/products/Flurbiprofen(Ansaid).html","C15H13FO2","free base","N/A","CC(C(O)=O)C1=CC(=C(C=C1)C2=CC=CC=C2)F",3.68,1,0,3]
["S1680","Disulfiram (NSC 190940)","c5","L1300-04","in 10mM DMSO","FDA,DMF,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","086889,086890,087973,087974,088792,088793,091563,091619,091681,202652,203916","Psychotic disorders","Apoptosis related,COVID-19,Dehydrogenase,Pyroptosis","Metabolism","Disulfiram (NSC 190940, Tetraethylthiuram disulfide, TETD) is a specific inhibitor of aldehyde-dehydrogenase (ALDH) with IC50 of 0.15 μM and 1.45 μM for hALDH1 and hALDH2, respectively. Disulfiram is used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram induces apoptosis. Disulfiram is also an inhibitor of pore formation by gasdermin D (GSDMD).",296.54,"97-77-8",59,198.96,"<1",0,"http://selleckchem.com/products/Disulfiram(Antabuse).html","C10H20N2S4","free base","NSC 190940, Tetraethylthiuram disulfide, TETD","CCN(CC)C(=S)SSC(=S)N(CC)CC",5.6,0,0,9]
["S1681","Mesalamine (5-ASA)","d5","L1300-04","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","076751,076841,091640,202065,203286,203574,203817,204354,207448,207873,208362,208953,209970,211858","Inflammation","Immunology & Inflammation related,IκB/IKK","NF-κB","Mesalamine (5-Aminosalicylic acid, 5-ASA, Mesalazine, Apriso, Asacol, Pentasa, Canasa) is a specific inhibitor of TNFα-induced IKK activity, used to treat inflammatory bowel disease.",153.14,"89-57-6",31,202.43,"<1",0,"http://selleckchem.com/products/Mesalamine(Lialda).html","C7H7NO3","free base","5-Aminosalicylic acid, 5-ASA, Mesalazine, Apriso, Asacol, Pentasa, Canasa","NC1=CC=C(O)C(=C1)C(O)=O",0.471,1,2,1]
["S1683","Ipratropium Bromide","e5","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.6;JP17;Martindale:The Extra Pharmacopoeia","074755,075111,075313,075441,075507,075552,075553,075562,075693,075835,075867,076025,076103,076155,076156,076291,076598,076664,077072,206543,207903","Immunology/Respiratory Disease","AChR","Neuronal Signaling","Ipratropium Bromide is an antagonist of M3 type muscarinic acetylcholine receptors, used for the treatment of chronic obstructive pulmonary disease (COPD).",412.37,"22254-24-6",83,201.28,83,201.28,"http://selleckchem.com/products/Ipratropium-bromide.html","C20H30BrNO3","Bromide","N/A","[Br-].CC(C)[N+]1(C)C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",-1.326,2,1,6]
["S1685","Sulfanilamide","f5","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","088718","Infection","Bacterial","Microbiology","Sulfanilamide (Sulphanilamide) is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.",172.2,"63-74-1",34,197.44,"<1",0,"http://selleckchem.com/products/Sulfanilamide.html","C6H8N2O2S","free base","N/A","NC1=CC=C(C=C1)[S](N)(=O)=O",-0.212,2,2,1]
["S1688","Betamethasone Dipropionate","g5","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.3;KP Ⅹ;BP2019;JP17;IP2010;Martindale:The Extra Pharmacopoeia","019136,019137,019140,019141,070274,070275,070281,070885,071012,071085,071143,071467,071476,071477,071882,072276,072526,072536,072538,073552,074271,074272,074304,074579,075276,075373,076215,076508,076543,076592,076603,076753,077111,077477,078930,206118,206389,208885,209896,210217,211540","Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Betamethasone Dipropionate (SCH 11460) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.",504.59,"5593-20-4",100,198.18,"<1",0,"http://selleckchem.com/products/Betamethasone-Dipropionate(Diprolene).html","C28H37FO7","Free Base","SCH 11460","CCC(=O)OCC(=O)C1(OC(=O)CC)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C",3.8,6,1,8]
["S1689","Meprednisone","h5","L1300-04","in 10mM DMSO","FDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","016053","Cancer/Hematology/Immunology/Inflammation/Ophthalmology","Glucocorticoid Receptor","Endocrinology & Hormones","Meprednisone (NSC 527579, SCH 4358) is a glucocorticoid and a methylated derivative of prednisone.",372.46,"1247-42-3",75,201.37,"<1",0,"http://selleckchem.com/products/Betapar(Meprednisone).html","C22H28O5","free base","NSC 527579, SCH 4358","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3C(=O)CC2(C)C1(O)C(=O)CO",1.536,3,1,2]
["S1690","Betamethasone Valerate","a6","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37 ;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","018860,018861,018864,018865,018866,018870,070051,070052,070053,070062,070484,070485,070486,071478,071883,078337,207144,208204","Endocrinology/Gastrointestinal Disease/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Betamethasone Valerate is a moderately potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.",476.58,"2152-44-5",95,199.34,"<1",0,"http://selleckchem.com/products/Betamethasone-valerate(Betnovate).html","C27H37FO6","free base","N/A","CCCCC(=O)OC1(C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)CO",3.666,4,2,7]
["S1691","Praziquantel","b6","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","208820","Infection","COVID-19,Parasite","Microbiology","Praziquantel is an anthelmintic effective against flatworms.",312.41,"55268-74-1",63,201.66,"<1",0,"http://selleckchem.com/products/Praziquantel(Biltricide).html","C19H24N2O2","free base","N/A","O=C1CN(CC2N1CCC3=CC=CC=C23)C(=O)C4CCCCC4",2.477,2,0,1]
["S1692","Busulfan (NSC-750)","c6","L1300-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","202259,205106,205139,205184,205672,207050,207794,209580,210148,210448,210931","Cancer/Hematology","Apoptosis related,DNA alkylator","DNA Damage/DNA Repair","Busulfan (NSC-750) is a cell cycle non-specific alkylating antineoplastic agent. Busulfan induces apoptosis.",246.3,"55-98-1",49,198.94,"<1",0,"http://selleckchem.com/products/Busulfan(Busulfex).html","C6H14O6S2","free base","NSC-750","C[S](=O)(=O)OCCCCO[S](C)(=O)=O",-0.289,2,0,7]
["S1693","Carbamazepine","d6","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","070231,070300,070429,071479,071696,071940,074649,075687,075712,075714,075875,075948,076697,077272,078115,078592,078746,078986,201106,205571","Neurological Disease","Autophagy,Sodium Channel","Transmembrane Transporters","Carbamazepine (Carbatrol, NSC 169864) is a sodium channel blocker with IC50 of 131 μM in rat brain synaptosomes.",236.27,"298-46-4",47,198.92,"<1",0,"http://selleckchem.com/products/Carbamazepine(Carbatrol).html","C15H12N2O","free base","NSC 169864","NC(=O)N1C2=C(C=CC=C2)C=CC3=C1C=CC=C3",2.679,1,1,0]
["S1696","Hydrocortisone (NSC 10483)","e6","L1300-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP35-NF30;BP2010;JP15;Martindale:The Extra Pharmacopoeia","009659,040247,040310,040351,040417,040503,040646,040761,040879,074171,080344,080355,080395,080400,080452,080456,080489,080496,080568,080624,080642,080692,080693,080732,080781,080848,081203,083140,083365,083999,084059,084243,084247,084969,084970,085025,085026,085027,085028,085070,085191,085282,085527,085662,085663,085733,086079,086080,086154,086155,086170,086256,086257,086271,086272,087315,087317,087795,087796,087838,088027,088029,088039,088061,088082,088539,088799,088842,088845,089024,089273,089413,089414,089682,089704,089705,089706,089754,203804,203810,207029","Endocrinology/Gastrointestinal Disease/Inflammation/Infection/Hematology/Metabolic Disease","Glucocorticoid Receptor","Endocrinology & Hormones","Hydrocortisone (NSC 10483, Cortisol) is a steroid hormone or glucocorticoid produced by the adrenal gland.",362.46,"50-23-7",73,201.4,"<1",0,"http://selleckchem.com/products/Hydrocortisone.html","C21H30O5","free base","Cortisol","CC12CCC(=O)C=C1CCC3C4CCC(O)(C(=O)CO)C4(C)CC(O)C23",1.283,2,2,2]
["S1701","Desonide","f6","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;USP38-NF33;Martindale:The Extra Pharmacopoeia","017010,017426,073548,074027,074254,075751,075860,202161,202470,207855,208836,209494,209729,209996,210998,212002","Immunology/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Desonide is a low potency topical corticosteroid.",416.51,"638-94-8",83,199.27,"<1",0,"http://selleckchem.com/products/Desonide.html","C24H32O6","free base","N/A","CC1(C)OC2CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC3(C)C2(O1)C(=O)CO",1.028,4,2,2]
["S1702","Didanosine","g6","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","077167,077275,078112,090094,090788","Infection","Reverse Transcriptase","Microbiology","Didanosine is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.",236.23,"69655-05-6",47,198.96,"<1",0,"http://selleckchem.com/products/Didanosine(Videx).html","C10H12N4O3","free base","N/A","OCC1CCC(O1)[N]2C=NC3=C2N=CNC3=O",-0.844,4,2,2]
["S1703","Divalproex Sodium","h6","L1300-04","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;IP2010","076941,077100,077254,077296,077567,077615,078182,078239,078290,078411,078445,078597,078700,078705,078755,078790,078791,078853,078919,078979,079080,079163,090062,090070,090161,090210,090407,090554,202419,203730","Neurological Disease","HDAC","Epigenetics","Divalproex Sodium, consisting of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form, is a HDAC inhibitor, used in the treatment for epilepsy.",310.41,"76584-70-8",62,199.74,62,199.74,"http://selleckchem.com/products/Divalproex-sodium.html","C8H16O2.C8H15O2.Na","Sodium Salt","N/A","[Na+].CCCC(CCC)C(O)=O.CCCC(CCC)C([O-])=O",4.025,1,0,10]
["S1704","Emtricitabine (BW 1592)","a7","L1300-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","079188,090488,091168","Infection","HBV,HIV,Reverse Transcriptase","Microbiology","Emtricitabine (BW1592, FTC) is a new nucleoside agent that has activity against both human immunodeficiency virus (HIV) and hepatitis B virus. It is a reverse transcriptase inhibitor. Intracellular half-life is 39 h.",247.25,"143491-57-0",49,198.18,49,198.18,"http://selleckchem.com/products/Emtricitabine.html","C8H10FN3O3S","free base","FTC, BW1592","NC1=NC(=O)N(C=C1F)C2CSC(CO)O2",-0.68,3,2,2]
["S1705","Progesterone (NSC 9704)","b7","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;KP Ⅹ; EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","009238,017362,075906,090845,091033,200456,200900,202121,205229,207724,208801,210965,211285","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Progesterone (NSC 9704, NSC 64377, Pregn-4-ene-3,20-dione) is an endogenous steroid hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. A potent agonist of the nuclear progesterone receptor (nPR) with Kd of 1 nM; An agonist of the membrane progesterone receptors(mPRs); An antagonist of the σ1 receptor.",314.46,"57-83-0",22,69.96,"<1",0,"http://selleckchem.com/products/Progesterone(Prometrium).html","C21H30O2","free base","NSC 64377, Pregn-4-ene-3,20-dione,NSC 9704","CC(=O)C1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C",3.86,2,0,1]
["S1706","Lamivudine (BCH-189)","c7","L1300-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","077221,077357,077464,077695,077980,078545,078636,078850,090198,090433,090457,091475,091606,200406,202032,202941,203260,203277,203564,203586,204002,204528,205217,206974,211306","Infection","COVID-19,Reverse Transcriptase","Microbiology","Lamivudine (BCH-189, GR109714X) is a potent nucleoside analog reverse transcriptase inhibitor, used for treatment of chronic HBV and HIV/AIDS. It works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase.",229.26,"134678-17-4",46,200.65,46,200.65,"http://selleckchem.com/products/Lamivudine(Epivir).html","C8H11N3O3S","free base","GR109714X, BCH-189","NC1=NC(=O)N(C=C1)C2CSC(CO)O2",-0.59,3,2,2]
["S1709","Estradiol","d7","L1300-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP39-NF34;BP2015;JP16;IP2010;Martindale:The Extra Pharmacopoeia","020167,020538,021048,040114,040138,040197,040275,040297,040326,075182,075233,201675,205256,206388,206685,208788,209767,210194,210264,210488,211293,211396","Angiology/Endocrinology","Estrogen/progestogen Receptor,Interleukins","Endocrinology & Hormones","Estradiol (17β-estradiol, β-Estradiol, E2, 17β-Oestradiol) is a human sex hormone and steroid, and the primary female sex hormone. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.",272.38,"50-28-2",54,198.25,"<1",0,"http://selleckchem.com/products/Estradiol.html","C18H24O2","free base","17β-estradiol, β-Estradiol, E2, 17β-Oestradiol","CC12CCC3C(CCC4=C3C=CC(=C4)O)C1CCC2O",3.838,0,2,0]
["S1712","Deferasirox (ICL-670)","e7","L1300-04","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","EP;Martindale:The Extra Pharmacopoeia","203560,208697,208882,209426,210920,211383","Hematology","Ferroptosis,P450 (e.g. CYP17)","Proteases","Deferasirox (ICL-670, CGP-72670) is an iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor. Deferasirox-induced iron depletion promotes BclxL downregulation and cell death.",373.36,"201530-41-8",74,198.2,"<1",0,"http://selleckchem.com/products/Deferasirox(Exjade).html","C21H15N3O4","free base","CGP-72670, ICL-670","OC(=O)C1=CC=C(C=C1)[N]2N=C(N=C2C3=CC=CC=C3O)C4=CC=CC=C4O",4.063,3,2,4]
["S1713","Piroxicam","f7","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37 ;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","073536,073637,073638,073651,074036,074043,074102,074103,074116,074118,074131,074148,074287,074460,074808,205585,206136,206152,207938,208340,208991,209256,210347","Inflammation","COX","Neuronal Signaling","Piroxicam (CP 16171) is a non-selective COX inhibitor, used in the treatment of rheumatoid and osteoarthritis.",331.35,"36322-90-4",66,199.19,"<1",0,"http://selleckchem.com/products/Piroxicam(Feldene).html","C15H13N3O4S","free base","CP 16171","CN1C(=C(O)C2=C(C=CC=C2)[S]1(=O)=O)C(=O)NC3=NC=CC=C3",0.501,4,2,2]
["S1714","Gemcitabine (LY-188011)","g7","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","078460,090644","Cancer/Respiratory Disease","Apoptosis related,Autophagy,DNA/RNA Synthesis,Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Gemcitabine (LY-188011, NSC 613327), a nucleic acid synthesis inhibitor, is a very potent and specific deoxycytidine analogue, used as chemotherapy. Gemcitabine induces a potent p53-dependent apoptosis.",263.2,"95058-81-4",52,197.57,52,197.57,"http://selleckchem.com/products/Gemcitabine(Gemzar).html","C9H11F2N3O4","Free Base","LY-188011, NSC 613327","NC1=NC(=O)N(C=C1)C2OC(CO)C(O)C2(F)F",-1.394,3,3,2]
["S1715","Glipizide","h7","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;EP9.7;BP2019;IP2010;Martindale:The Extra Pharmacopoeia","074223,074226,074305,074370,074378,074387,074438,074497,074542,074550,074619,075795,076159,076467,077820,202298,203499,204720,206928","Endocrinology/Metabolic Disease","Potassium Channel","Transmembrane Transporters","Glipizide (CP-28720,K 4024) is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes.",445.54,"29094-61-9",89,199.76,"<1",0,"http://selleckchem.com/products/Glipizide(Glucotrol).html","C21H27N5O4S","free base","CP-28720,K 4024","CC1=NC=C(N=C1)C(=O)NCCC2=CC=C(C=C2)[S](=O)(=O)NC(=O)NC3CCCCC3",1.902,6,3,7]
["S1716","Glyburide (Glibenclamide)","a8","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37","074388,075947,076257,077537,090937,203379,203581,206079,206483,206749","Endocrinology","Potassium Channel","Transmembrane Transporters","Glyburide (Glibenclamide) is a known blocker of vascular ATP-sensitive K+ channels (KATP), used in the treatment of type 2 diabetes.",494,"10238-21-8",99,200.4,"<1",0,"http://selleckchem.com/products/Glyburide(Diabeta).html","C23H28ClN3O5S","free base","Glibenclamide","COC1=C(C=C(Cl)C=C1)C(=O)NCCC2=CC=C(C=C2)[S](=O)(=O)NC(=O)NC3CCCCC3",4.14,5,3,8]
["S1717","Fomepizole","b8","L1300-04","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia","078368,078537,078639,079033","Others","Dehydrogenase","Metabolism","Fomepizole (4-methylpyrazole, Antizol, Antizol-Vet) is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.",82.1,"7554-65-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/Fomepizole(Antizol).html","C4H6N2","free base","4-methylpyrazole, Antizol, Antizol-Vet","CC1=C[NH]N=C1",0.76,1,1,0]
["S1718","Adefovir Dipivoxil (GS 0840)","c8","L1300-04","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia","202051,205459","Infection","Reverse Transcriptase","Microbiology","Adefovir Dipivoxil (GS 0840) is a reverse transcriptase inhibitor, used in the treatment of chronic hepatitis B virus (HBV).",501.47,"142340-99-6",100,199.41,"<1",0,"http://selleckchem.com/products/Adefovir-Dipivoxil(Preveon).html","C20H32N5O8P","free base","GS 0840","CC(C)(C)C(=O)OCO[P](=O)(COCC[N]1C=NC2=C1N=CN=C2N)OCOC(=O)C(C)(C)C",1.666,10,1,15]
["S1719","Zalcitabine","d8","L1300-04","in 10mM DMSO","FDA,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","020199","Infection","Reverse Transcriptase","Microbiology","Zalcitabine (NSC 606170, Ro 24-2027/000) is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI).",211.22,"7481-89-2",7,33.14,42,198.84,"http://selleckchem.com/products/Zalcitabine.html","C9H13N3O3","free base","NSC 606170, Ro 24-2027/000","NC1=NC(=O)N(C=C1)C2CCC(CO)O2",-0.991,3,2,2]
["S1721","Azathioprine","e8","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;IP2010;JP17;Martindale:The Extra Pharmacopoeia","071056,074069,075568,077621","Inflammation","Rho","Cell Cycle","Azathioprine(BW 57-322) is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases.",277.26,"446-86-6",54,194.76,"<1",0,"http://selleckchem.com/products/Azathioprine(Azasan).html","C9H7N7O2S","free base","BW 57-322","C[N]1C=NC(=C1SC2=C3[NH]C=NC3=NC=N2)[N+]([O-])=O",1.071,4,1,3]
["S1723","Indomethacin (NSC-77541)","f8","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;KP Ⅹ;IP2010;CP2005","018690,018730,018806,018829,018851,018858,022536,070067,070068,070326,070327,070353,070354,070487,070488,070529,070530,070592,070624,070635,070651,070673,070674,070719,070756,070782,070784,070785,070813,070900,071148,071149,071342,071343,071412,071635,072410,072996,072997,073314,074464,076114,076666,079175,090403,091240,091276,091401,091549,200529,201807,202139,202572,202706,202711,203501,204243,204853,205215","Inflammation","COX","Neuronal Signaling","Indomethacin (NSC-77541, Indometacin) is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively, used to reduce fever, pain, stiffness, and swelling.",357.79,"53-86-1",72,201.24,"<1",0,"http://selleckchem.com/products/Indomethacin(Indocid).html","C19H16ClNO4","free base","Indometacin,NSC-77541","COC1=CC=C2[N](C(=C(CC(O)=O)C2=C1)C)C(=O)C3=CC=C(Cl)C=C3",4.235,3,0,4]
["S1725","Terbinafine","g8","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","076377,076390,076713,077065,077136,077137,077195,077223,077511,077533,077714,077919,078157,078163,078199,078229,078297","Infection","Fungal","Microbiology","Terbinafine (SF 86-327,TDT 067) is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.",291.43,"91161-71-6",58,199.02,"<1",0,"http://selleckchem.com/products/Terbinafine(Lamisil).html","C21H25N","Free Base","SF 86-327,TDT 067","CN(C\\C=C\\C#CC(C)(C)C)CC1=CC=CC2=CC=CC=C12",5.335,0,0,6]
["S1727","Levonorgestrel","h8","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","020627,078665,078666,090740,091328,200670,202246,202334,202380,202508,202684,202684,202739,202740,202740,204044,205329,207044,207660","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Levonorgestrel (D-Norgestrel) is a female hormone that prevents ovulation.",312.45,"797-63-7",45,144.02,"<1",0,"http://selleckchem.com/products/Levonorgestrel(Levonelle).html","C21H28O2","free base","D-Norgestrel","CCC12CCC3C(CCC4=CC(=O)CCC34)C1CCC2(O)C#C",4.771,1,0,1]
["S1729","Gemfibrozil","a9","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2","072929,073466,074156,074256,074270,074360,074442,074452,074615,075034,077836,078012,078207,078599,079072,079239,202726,203266,204189","Cardiovascular Disease","PPAR","Metabolism","Gemfibrozil (CI-719) is an activator of peroxisome proliferator-activated receptor-alpha (PPARα), used for the treatment of hypercholesterolemia and hypertriglyceridemia.",250.33,"25812-30-0",50,199.74,"<1",0,"http://selleckchem.com/products/Gemfibrozil(Lopid).html","C15H22O3","free base","CI-719","CC1=CC(=C(C)C=C1)OCCCC(C)(C)C(O)=O",4.172,2,0,6]
["S1730","Indapamide","b9","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","074299,074461,074498,074585,074594,074665,074722,075105,075201","Cardiovascular Disease","Others","Others","Indapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.",365.83,"26807-65-8",73,199.55,"<1",0,"http://selleckchem.com/products/Indapamide(Lozol).html","C16H16ClN3O3S","free base","N/A","CC1CC2=C(C=CC=C2)N1NC(=O)C3=CC=C(Cl)C(=C3)[S](N)(=O)=O",2.664,3,2,3]
["S1732","Mitotane","c9","L1300-04","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","016885","Cancer/Endocrinology","Others","Others","Mitotane (NCI-C04933), is an antineoplastic medication used in the treatment of adrenocortical carcinoma.",320.04,"53-19-0",64,199.98,"<1",0,"http://selleckchem.com/products/Mitotane(Lysodren).html","C14H10Cl4","free base","NCI-C04933","ClC(Cl)C(C1=CC=C(Cl)C=C1)C2=C(Cl)C=CC=C2",5.745,0,0,3]
["S1733","Methylprednisolone (NSC-19987)","d9","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","040183,040189,040194,040232,085650,086159,086161,087341,088497,089207,089208,089209,204072,206751,209097,210985,086906,087535","Cancer/Immunology/Inflammation","ACE,Apoptosis related,Autophagy,Glucocorticoid Receptor,Immunology & Inflammation related,Interleukins","Endocrinology & Hormones","Methylprednisolone (NSC-19987,U 7532) is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.",374.47,"83-43-2",75,200.28,"<1",0,"http://selleckchem.com/products/Methylprednisolone.html","C22H30O5","free base","NSC-19987,U 7532","CC1CC2C3CCC(O)(C(=O)CO)C3(C)CC(O)C2C4(C)C=CC(=O)C=C14",1.512,2,2,2]
["S1734","Meloxicam","e9","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Martindale:The Extra Pharmacopoeia","077882,077918,077920,077921,077923,077925,077927,077928,077929,077930,077931,077932,077933,077934,077935,077936,077937,077938,077944,078008,078039,078102,211398","Inflammation","COX","Neuronal Signaling","Meloxicam is a selective COX inhibitor, used to relieve pain and fever effects.",351.4,"71125-38-7",30,85.37,"<1",0,"http://selleckchem.com/products/Meloxicam(Mobic).html","C14H13N3O4S2","free base","N/A","CN1C(=C(O)C2=C(C=CC=C2)[S]1(=O)=O)C(=O)NC3=NC=C(C)S3",0.255,4,2,2]
["S1735","Mesna","f9","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","075739,075764,075811,076488,090913,203364,206992","Others","Others","Others","Mesna, a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents.",164.18,"19767-45-4",33,201,7,42.64,"http://selleckchem.com/products/Mesna(Uromitexan).html","C2H5NaO3S2","Sodium Salt","N/A","[Na+].[O-][S](=O)(=O)CCS",-2.227,0,0,2]
["S1736","Methocarbamol","g9","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;KP Ⅹ;Martindale:The Extra Pharmacopoeia","040413,040489,083605,084231,084259,084276,084277,084323,084448,084449,084471,084486,084488,084615,084616,084648,084649,084675,084756,084846,084924,084927,084928,085033,085123,085137,085159,085180,085192,085658,085660,085718,085961,085963,086459,086988,086989,087282,087283,087453,087454,087589,087590,087660,087661,088646,088647,088731,089082,089417,089418,089849,090200,200958,203550,204404,205354,205404,206071,206128,207496,207522,208116,208507,209312,209331,211504,","Others","Carbonic Anhydrase","Metabolism","Methocarbamol (AHR 85) is a carbonic anhydrase inhibitor, used as a central muscle relaxant to treat skeletal muscle spasms.",241.24,"532-03-6",48,198.97,2,8.29,"http://selleckchem.com/products/Methocarbamol(Robaxin).html","C11H15NO5","free base","AHR 85","COC1=C(OCC(O)COC(N)=O)C=CC=C1",0.916,4,2,7]
["S1737","Prednisolone (NSC-9900)","h9","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","BP2013;JP16;IP2010;USP35-NF30;Martindale:The Extra Pharmacopoeia","040192,040287,040313,040322,040323,040364,040399,040401,040423,040570,040571,040775,080211,080236,080307,080322,080324,080325,080326,080327,080339,080342,080351,080354,080358,080378,080398,080531,080534,080562,080625,080748,080780,083675,084426,084439,084542,084773,085085,085170,085415,085416,087987,088892","Endocrinology/Hematology/Immunology/Inflammation","Glucocorticoid Receptor,Immunology & Inflammation related","Endocrinology & Hormones","Prednisolone (NSC-9900) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.",360.44,"50-24-8",72,199.76,"<1",0,"http://selleckchem.com/products/Prednisolone(Hydroretrocortine).html","C21H28O5","Free Base","NSC-9900","CC12CC(O)C3C(CCC4=CC(=O)C=CC34C)C1CCC2(O)C(=O)CO",1.26,2,2,2]
["S1738","Telmisartan","a10","L1300-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.7;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","078710,090032,202130,202397,203171,203325,203867,204164,204415,205150,205901,206511,207016,207843,207882,208605","Cardiovascular Disease","Angiotensin Receptor","GPCR & G Protein","Telmisartan (BIBR 277) is an angiotensin II receptor antagonist (ARB) used in the management of hypertension.",514.62,"144701-48-4",13,25.26,"<1",0,"http://selleckchem.com/products/Telmisartan(Micardis).html","C33H30N4O2","free base","BIBR 277","CCCC1=NC2=C(C=C(C=C2C)C3=NC4=C(C=CC=C4)[N]3C)[N]1CC5=CC=C(C=C5)C6=CC=CC=C6C(O)=O",7.799,3,0,7]
["S1739","Thiabendazole","b10","L1300-04","in 10mM DMSO","FDA,DMF","USP42-NF37;IP2010","016096,016097","Infection/Parasitology","P450 (e.g. CYP17)","Metabolism","Thiabendazole inhibits the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property, used as an anthelmintic and fungicide agent. It is a potent inhibitor of  cytochrome P450 1A2 (CYP1A2).",201.25,"148-79-8",40,198.76,"<1",0,"http://selleckchem.com/products/Thiabendazole.html","C10H7N3S","free base","N/A","[NH]1C2=C(C=CC=C2)N=C1C3=CSC=N3",2.154,2,1,1]
["S1740","Guaifenesin","c10","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.4;KP Ⅹ;BP2017;JP17;Martindale:The Extra Pharmacopoeia","078912,091009,207342,209215,209254","Respiratory Disease","Others","Others","Guaifenesin is an expectorant used to relieve chest congestion.",198.22,"93-14-1",40,201.8,25,126.12,"http://selleckchem.com/products/Guaifenesin(Guaiphenesin).html","C10H14O4","free base","N/A","COC1=C(OCC(O)CO)C=CC=C1",0.747,2,2,5]
["S1741","Rifabutin (LM427)","d10","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Martindale:The Extra Pharmacopoeia","090033","Infection","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Bacterial","Microbiology","Rifabutin (LM427, Ansamycin) is a semisynthetic ansamycin antibiotic, used in the treatment of Mycobacterium avium intracellulare (MAI) and tuberculosis.",847,"72559-06-9",60,70.84,"<1",0,"http://selleckchem.com/products/Rifabutin(Mycobutin).html","C46H62N4O11","free base","LM427, Ansamycin","COC1\\C=C\\OC2(C)OC3=C(C2=O)C4=C(C(=C3C)O)C(=O)C(=C5NC6(CCN(CC6)CC(C)C)N=C45)NC(=O)/C(=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)C",3.931,9,5,5]
["S1742","Nevirapine (NSC 641530)","e10","L1300-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.3;BP2019;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","077429,077521,077702,077956,078195,078584,078644,078864,078887,090688,202212,202523,203021,203080,203176,203411,204621,205258,205651,205921,206271,206448,206879,207064,207467,207684,207698,208616","Infection","Reverse Transcriptase","Microbiology","Nevirapine (NSC 641530,NVP) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.",266.3,"129618-40-2",53,199.02,"<1",0,"http://selleckchem.com/products/Nevirapine(Viramune).html","C15H14N4O","free base","NSC 641530,NVP","CC1=CC=NC2=C1NC(=O)C3=C(N=CC=C3)N2C4CC4",2.293,3,1,1]
["S1743","Esomeprazole magnesium","f10","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA",null,"021153,021957,022101","Gastrointestinal Disease","ATPase,Proton Pump","Transmembrane Transporters","Esomeprazole Magnesium(NEXIUM) is a proton pump inhibitor to reduce gastric acid secretion through inhibition of H(+)/K(+)-ATPase in gastric parietal cells.",713.12,"161973-10-0",143,200.53,"<1",0,"http://selleckchem.com/products/nexium-esomeprazole-magnesium.html","C34H36MgN6O6S2","Magnesium salt","NEXIUM","[Mg++].COC1=CC2=C([N-]C(=N2)[S](=O)CC3=C(C)C(=C(C)C=N3)OC)C=C1.COC4=CC5=C([N-]C(=N5)[S](=O)CC6=NC=C(C)C(=C6C)OC)C=C4",6.1,10,0,10]
["S1744","Nicotinic Acid","g10","L1300-04","in 10mM DMSO","DMF,EMA,HMA,CFDA,PMDA","USP42-NF37;EP9.3;BP2019;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Vitamin","Metabolism","Nicotinic Acid is a water-soluble vitamin belonging to the vitamin B family.",123.11,"59-67-6",25,203.07,2,16.25,"http://selleckchem.com/products/Niacin(Nicotinic-acid).html","C6H5NO2","free base","N/A","OC(=O)C1=CC=CN=C1",0.309,2,0,1]
["S1747","Nimodipine","h10","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Martindale:The Extra Pharmacopoeia","076740,077067,077811,090103,201832","Cardiovascular Disease","Autophagy,Calcium Channel","Transmembrane Transporters","Nimodipine (BAY E 9736) is a dihydropyridine calcium channel blocker and an autophagy inhibitor, used in the treatment of high blood pressure.",418.44,"66085-59-4",84,200.75,"<1",0,"http://selleckchem.com/products/Nimodipine(Nimotop).html","C21H26N2O7","free base","BAY E 9736","COCCOC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OC(C)C)C",2.361,5,1,10]
["S1748","Nisoldipine","a11","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","079051,091001","Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Nisoldipine (Sular, BAY K 5552) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM.",388.41,"63675-72-9",77,198.24,"<1",0,"http://selleckchem.com/products/Nisoldipine(Sular).html","C20H24N2O6","free base","BAY K 5552","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC=C2[N+]([O-])=O)C(=O)OCC(C)C)C",2.958,4,1,8]
["S1750","Octocrylene","b11","L1300-04","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","021471,022009,021502,021501","Others","Others","Others","Octocrylene is an organic compound used as an ingredient in sunscreens and cosmetics.",361.48,"6197-30-4","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/octocrylene.html","C24H27NO2","free base","N/A","CCCCC(CC)COC(=O)C(C#N)=C(C1=CC=CC=C1)C2=CC=CC=C2",6.487,2,0,10]
["S1754","Oxybutynin","c11","L1300-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","090526","Others","AChR","Neuronal Signaling","Oxybutynin is a competitive antagonist of the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor, used to relieve urinary and bladder difficulties.",357.49,"5633-20-5",71,198.61,"<1",0,"http://selleckchem.com/products/Oxybutynin(Ditropan).html","C22H31NO3","Free Base","N/A","CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)C2=CC=CC=C2",4.646,2,0,10]
["S1756","Enoxacin","d11","L1300-04","in 10mM DMSO","FDA,DMF,CFDA","KP Ⅹ;JP17;CP2005;Martindale:The Extra Pharmacopoeia","019616","Infection","Topoisomerase","DNA Damage/DNA Repair","Enoxacin (AT-2266, CI919, Pd107779, NSC 629661) is an oral broad-spectrum fluoroquinolone antibacterial agent by inhibiting bacterial DNA gyrase and topoisomerase IV, used to treat a wide variety of infections.",320.32,"74011-58-8",32,99.9,"<1",0,"http://selleckchem.com/products/Enoxacin(Penetrex).html","C15H17FN4O3","free base","AT-2266, CI919, Pd107779, NSC 629661","CCN1C=C(C(O)=O)C(=O)C2=CC(=C(N=C12)N3CCNCC3)F",-1.483,3,1,3]
["S1759","Pitavastatin (NK-104) calcium","e11","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","JP17;Martindale:The Extra Pharmacopoeia","205932,205955,206015,206029,206070","Cardiovascular Disease","Apoptosis related,Autophagy,COVID-19,HMG-CoA Reductase,Mitophagy","Metabolism","Pitavastatin Calcium (NK-104, P-872441, itavastatin, nisvastatin), a novel member of the medication class of statins, is a calcium salt formulation of pitavastatin which is a highly effective HMG-CoA reductase inhibitor. Pitavastatin Calcium attenuates AGEs-induced mitophagy via inhibition of ROS generation. Pitavastatin Calcium induces autophagy and apoptosis.",880.98,"147526-32-7",51,57.89,"<1",0,"http://selleckchem.com/products/Pitavastatin-calcium(Livalo).html","C50H46CaF2N2O8","Calcium salt","NK-104, P-872441, itavastatin, nisvastatin","[Ca++].OC(CC(O)C=CC1=C(C2=CC=C(F)C=C2)C3=CC=CC=C3N=C1C4CC4)CC([O-])=O.OC(CC(O)C=CC5=C(C6=CC=C(F)C=C6)C7=CC=CC=C7N=C5C8CC8)CC([O-])=O",4.96,2,4,16]
["S1760","Rifapentine","f11","L1300-04","in 10mM DMSO","FDA,CFDA,NDC","Martindale:The Extra Pharmacopoeia","021024","Infection/Respiratory Disease","DNA/RNA Synthesis","DNA Damage/DNA Repair","Rifapentine (MDL473) is an antibiotic, which inhibits DNA-dependent RNA polymerase activity, used to treat tuberculosis.",877.03,"61379-65-5",100,114.02,"<1",0,"http://selleckchem.com/products/Rifapentine(Priftin).html","C47H64N4O12","free base","MDL473","COC1\\C=C\\OC2(C)OC3=C(C2=O)C4=C(O)C(=C(NC(=O)\\C(=C\\C=C\\C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)C)C(=C4C(=C3C)O)O)\\C=N\\N5CCN(CC5)C6CCCC6",4.664,8,6,6]
["S1761","Suprofen","g11","L1300-04","in 10mM DMSO","FDA,DMF,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","019387","Inflammation","COX","Neuronal Signaling","Suprofen(TN-762) is a dual COX-1/COX-2 inhibitor, used as a non-steroidal anti-inflammatory analgesic and antipyretic.",260.31,"40828-46-4",52,199.76,"<1",0,"http://selleckchem.com/products/Suprofen(Profenal).html","C14H12O3S","free base","TN-762","CC(C(O)=O)C1=CC=C(C=C1)C(=O)C2=CC=CS2",3.314,2,0,4]
["S1762","Pyrazinamide","h11","L1300-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","080157,081319","Infection","Bacterial","Microbiology","Pyrazinamide (Pyrazinoic Acid Amide) is an agent used to treat tuberculosis.",123.11,"98-96-4",25,203.07,12,97.47,"http://selleckchem.com/products/Pyrazinamide(Pyrazinoic-acid-amide).html","C5H5N3O","free base","Pyrazinoic Acid Amide","NC(=O)C1=NC=CN=C1",-1.041,3,1,1]
["S1763","Quetiapine (ICI-204636) fumarate","a2","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.6;JP17;IP2010;Martindale:The Extra Pharmacopoeia","077380,077745,078679,090120,090323,090482,090681,090749,090757,090960,091388,200363,201109,201190,201504,201762,202152,202228,202674,202939,203150,203359,203390,204203,204253,206252,206260,207655,208947,209497,209635,211405","Neurological Disease","Dopamine Receptor","Neuronal Signaling","Quetiapine Fumarate (ICI-204636) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression and shows affinity for various neurotransmitter receptors including serotonin, dopamine, histamine, and adrenergic receptors.",883.09,"111974-72-2",36,40.77,"<1",0,"http://selleckchem.com/products/Quetiapine-fumarate(Seroquel).html","C46H54N6O8S2","Fumarate","ICI-204636 fumarate","OCCOCCN1CCN(CC1)C2=NC3=CC=CC=C3SC4=C2C=CC=C4.OCCOCCN5CCN(CC5)C6=NC7=CC=CC=C7SC8=C6C=CC=C8.OC(=O)\\C=C\\C(O)=O",-0.718,6,2,14]
["S1764","Rifampin (NSC-113926)","b2","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;IP2010","064150,064217,065028,065390,065421,065502,090034,091181,204101,205039,206736","Infection","Antibiotics for Plant Cell Culture,Antineoplastic and Immunosuppressive Antibiotics,DNA/RNA Synthesis,Selection Antibiotics for Transfected Cell","DNA Damage/DNA Repair","Rifampin (NSC-113926, Rimactane, Rifampicin) is a DNA-dependent RNA polymerase inhibitor, used to treat a number of bacterial infections.",822.94,"13292-46-1",100,121.52,"<1",0,"http://selleckchem.com/products/Rifampin(Rifadin).html","C43H58N4O12","free base","Rimactane, Rifampicin,NSC-113926","COC1\\C=C\\OC2(C)OC3=C(C2=O)C4=C(O)C(=C(NC(=O)\\C(=C\\C=C\\C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)C)C(=C4C(=C3C)O)O)\\C=N\\N5CCN(C)CC5",3.262,8,6,5]
["S1768","Cefditoren Pivoxil","c2","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","KP Ⅹ;JP17;USP32-NF27;Martindale:The Extra Pharmacopoeia","021222","Infection","Antibiotics,Bacterial","Microbiology","Cefditoren Pivoxil (ME-1207) is a broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria.",620.72,"117467-28-4",100,161.1,"<1",0,"http://selleckchem.com/products/Cefditoren-pivoxil.html","C25H28N6O7S3","free base","ME-1207","CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C)\\C=C/C3=C(C)N=CS3)C4=CSC(=N4)N",1.926,10,2,12]
["S1770","Sulfadiazine","d2","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","004054,004122,004125,040091,080081,080084,080088","Infection","Antibiotics","Microbiology","Sulfadiazine is a sulfonamide antibiotic.",250.28,"68-35-9",50,199.78,"<1",0,"http://selleckchem.com/products/Sulfadiazine.html","C10H10N4O2S","free base","N/A","NC1=CC=C(C=C1)[S](=O)(=O)NC2=NC=CC=N2",0.313,4,2,3]
["S1771","Chlorprothixene","e2","L1300-05","in 10mM DMSO","FDA,CFDA","EP9.8;BP2019;Martindale:The Extra Pharmacopoeia","012486,012487,016149","Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Chlorprothixene(Minithixen,Truxal) has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively.",315.86,"113-59-7",6,19,"<1",0,"http://selleckchem.com/products/Chlorprothixene.html","C18H18ClNS","free base","Minithixen,Truxal","CN(C)CC/C=C1/C2=CC=CC=C2SC3=C1C=C(Cl)C=C3",5.123,0,0,3]
["S1773","Oxytetracycline (Terramycin)","f2","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,PMDA","EP9.2;JP17;BP2017;USP40-NF35;Ph.Int_5th ;IP2010;Martindale:The Extra Pharmacopoeia","050286,050287,060567,060586,060595","Infection","Antibiotics,Bacterial,Selection Antibiotics for Transfected Cell","Others","Oxytetracycline(Terramycin) is a broad-spectrum tetracycline antibiotic, used to treat infections with bacteria.",460.43,"79-57-2",92,199.81,"<1",0,"http://selleckchem.com/products/Oxytetracycline(Terramycin).html","C22H24N2O9","free base","Terramycin","CN(C)C1C2C(O)C3C(=C(O)C4=C(C=CC=C4O)C3(C)O)C(=O)C2(O)C(=O)C(=C1O)C(N)=O",-1.904,3,5,2]
["S1774","Thioguanine (NSC 752)","g2","L1300-05","in 10mM DMSO","FDA,NDC","USP42-NF37","012429","Cancer/Hematology","DNA Methyltransferase","Epigenetics","Thioguanine (NSC 752, 6-Thioguanine, 2-Amino-6-purinethiol), a purine antimetabolite, inhibits DNMT1 activity through ubiquitin-targeted degradation, used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis) and organ transplant recipients.",167.19,"154-42-7",9,53.83,"<1",0,"http://selleckchem.com/products/Thioguanine.html","C5H5N5S","free base","NSC 752,6-Thioguanine, 2-Amino-6-purinethiol","NC1=NC(=S)C2=C(N1)N=C[NH]2",0.236,2,3,0]
["S1775","Thiotepa","h2","L1300-05","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","USP42-NF37;BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia","011683,075547,075698,075730,209150,210337","Cancer","Antineoplastic and Immunosuppressive Antibiotics","Others","Thiotepa (Thioplex, Tiofosyl, Tiofosfamid, Triethylenethiophosphoramide) is an alkylating agent used to treat cancer.",189.22,"52-24-4",100,528.49,100,528.49,"http://selleckchem.com/products/thiotepa-thioplex.html","C6H12N3PS","free base","Tiofosyl, Tiofosfamid, Triethylenethiophosphoramide","S=[P](N1CC1)(N2CC2)N3CC3",-0.762,0,0,3]
["S1776","Toremifene Citrate (NK 622)","a3","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","208813","Cancer","Estrogen/progestogen Receptor","Endocrinology & Hormones","Toremifene Citrate (NK 622, NSC 613680) is an oral selective estrogen receptor modulator (SERM), used in the treatment of advanced breast cancer.",598.08,"89778-27-8",100,167.2,"<1",0,"http://selleckchem.com/products/Toremifene-Citrate(Fareston).html","C32H36ClNO8","Citrate","NSC 613680,NK 622 Citrate","CN(C)CCOC1=CC=C(C=C1)\\C(=C(CCCl)/C2=CC=CC=C2)C3=CC=CC=C3.OC(=O)CC(O)(CC(O)=O)C(O)=O",1.945,4,0,14]
["S1777","Ethionamide","b3","L1300-05","in 10mM DMSO","FDA,DMF,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","013026","Infection","Antibiotics","Microbiology","Ethionamide (Bayer 5312) is an antibiotic used in the treatment of tuberculosis.",166.24,"536-33-4",33,198.51,"<1",0,"http://selleckchem.com/products/Ethionamide.html","C8H10N2S","free base","Bayer 5312","CCC1=NC=CC(=C1)C(N)=S",1.498,1,1,2]
["S1778","Trifluridine (NSC 75520)","c3","L1300-05","in 10mM DMSO","FDA,DMF,EMA,NDC","USP42-NF37;BP2019;Martindale:The Extra Pharmacopoeia","074311,205438","Infection/Ophthalmology","DNA/RNA Synthesis,Thymidylate Synthase","DNA Damage/DNA Repair","Trifluridine (NSC 529182, NSC 75520, Viroptic, Trifluorothymidine, TFT) is an anti-herpesvirus antiviral agent by interacting viral DNA replication, used primarily on the eye.",296.2,"70-00-8",59,199.19,59,199.19,"http://selleckchem.com/products/Trifluridine(Viroptic).html","C10H11F3N2O5","free base","NSC 529182, NSC 75520, Viroptic, Trifluorothymidine, TFT","OCC1OC(CC1O)N2C=C(C(=O)NC2=O)C(F)(F)F",-0.782,3,3,3]
["S1782","Azacitidine (5-Azacytidine)","d3","L1300-05","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","201537,204949,207234,207475,207518,208216,209540,210748","Cancer","Autophagy,DNA Methyltransferase,Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Azacitidine (5-Azacytidine, 5-AzaC, Ladakamycin, AZA, 5-Aza, CC-486,NSC 102816) is a nucleoside analogue of cytidine that specifically inhibits DNA methylation by trapping DNA methyltransferases. Azacitidine induces mitochondrial apoptosis and autophagy.",244.2,"320-67-2",48,196.56,"<1",0,"http://selleckchem.com/products/Azacitidine(Vidaza).html","C8H12N4O5","free base","5-AzaC,Ladakamycin, AZA,5-Aza, CC-486,NSC 102816,5-Azacytidine","NC1=NC(=O)N(C=N1)C2OC(CO)C(O)C2O",-2.505,4,4,2]
["S1784","Vidarabine","e3","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,PMDA","USP36-NF31;Martindale:The Extra Pharmacopoeia","050486,050523","Infection","DNA/RNA Synthesis","DNA Damage/DNA Repair","Vidarabine is an antiviral drug by interfering with the synthesis of viral DNA, used to treat herpes simplex and varicella zoster viruses.",267.24,"5536-17-4",53,198.32,3,11.23,"http://selleckchem.com/products/Vidarabine(Vira-A).html","C10H13N5O4","free base","N/A","NC1=C2N=C[N](C3OC(CO)C(O)C3O)C2=NC=N1",-1.881,4,4,2]
["S1786","Verteporfin (CL 318952)","f3","L1300-05","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","021119","Angiology/Cancer/Ophthalmology","Apoptosis related,Autophagy,TEAD,VDA,YAP","Angiogenesis","Verteporfin (CL 318952, Visudyne) is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth.  It is also a potent second-generation photosensitizing agent derived from porphyrin. Verteporfin is an autophagy inhibitor. Verteporfin inhibits cell proliferation and induces apoptosis.",718.79,"129497-78-5",100,139.12,"<1",0,"http://selleckchem.com/products/Verteporfin(Visudyne).html","C41H42N4O8","free base","CL 318952, Visudyne","COC(=O)CCC1=C(C)C2=CC3=NC(=CC4=C(C)C(=C([NH]4)C=C5N=C(C=C1[NH]2)C(=C5C)CCC(O)=O)C=C)C6=CC=C(C(C(=O)OC)C36C)C(=O)OC",7.789,9,2,12]
["S1787","Teniposide","g3","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","020119","Cancer/Hematology","Topoisomerase","DNA Damage/DNA Repair","Teniposide (NSC 122819, VM-26) is a chemotherapeutic medication mainly used in the treatment of childhood acute lymphocytic leukemia (ALL).",656.65,"29767-20-2",40,60.92,"<1",0,"http://selleckchem.com/products/Teniposide(Vumon).html","C32H32O13S","free base","NSC 122819, VM-26","COC1=CC(=CC(=C1O)OC)C2C3C(COC3=O)C(OC4OC5COC(OC5C(O)C4O)C6=CC=CS6)C7=CC8=C(OCO8)C=C27",2.516,10,3,6]
["S1789","Tetrabenazine (Xenazine)","h3","L1300-05","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia","204574,206129,206686,207682,208826,209284,209739,210544","Neurological Disease","Dopamine Receptor","Neuronal Signaling","Tetrabenazine(Xenazine,Ro 1-9569) acts primarily as a reversible high-affinity inhibitor of mono-amine uptake into granular vesicles of presynaptic neurons by binding selectively to VMAT-2; Also blocks dopamine D2 receptors, but this affinity is 1,000-fold lower than its affinity for VMAT-2.",317.42,"58-46-8",58,182.72,"<1",0,"http://selleckchem.com/products/Tetrabenazine(Nitoman).html","C19H27NO3","free base","Xenazine,Ro 1-9569","COC1=CC2=C(C=C1OC)C3CC(=O)C(CC(C)C)CN3CC2",3.365,3,0,4]
["S1790","Rifaximin","a4","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","BP2019;EP9.2;KP Ⅹ;Martindale:The Extra Pharmacopoeia","021361,022554","Infection","DNA/RNA Synthesis","DNA Damage/DNA Repair","Rifaximin is a RNA synthesis inhibitor by binding the β subunit of the bacterial DNA-dependent RNA polymerase, used to treat traveler's diarrhea caused by certain bacteria.",785.88,"80621-81-4",47,59.81,"<1",0,"http://selleckchem.com/products/Rifaximin(Xifaxan).html","C43H51N3O11","free base","N/A","COC1\\C=C\\OC2(C)OC3=C(C2=O)C4=C(C(=C3C)O)C(=C(NC(=O)\\C(=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)C)C5=C4N=C6C=C(C)C=C[N]56)O",4.805,8,5,3]
["S1791","Bacitracin Zinc","b4","L1300-05","in 10mM DMSO","FDA,NDC,DMF","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,KP Ⅹ,BP2017,Ph.Int_5th","064028,064046,065022","Infection","Antibiotics,Bacterial","Microbiology","Bacitracin(Zinc Bacitracin) is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane. It inhibits cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.",1486.07,"1405-89-6",100,67.29,"<1",0,"http://www.selleck.cn/products/bacitracin-zinc.html","C66H101N17O16SZn","Free Base","Zinc Bacitracin","[Zn++].CCC(C)C(N)C1=NCC(S1)C(=O)NC(CC(C)C)C(=O)NC(CCC([O-])=O)C(=O)NC(C(C)CC)C(=O)NC2CCCCNC(=O)C(CC(N)=O)NC(=O)C(CC([O-])=O)NC(=O)C(CC3=C[NH]C=N3)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(NC(=O)C(CCCN)NC2=O)C(C)CC",-3.993,14,15,31]
["S1792","Simvastatin (MK 733)","c4","L1300-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.7;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","021961,076052,076285,076532,076685,077691,077752,077766,077837,078034,078103,078155,078735,090383,090868,200895,206557","Cardiovascular Disease","Apoptosis related,Autophagy,Ferroptosis,HMG-CoA Reductase,Mitophagy","Metabolism","Simvastatin (MK-0733, MK 733) is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM in cell-free assays. Simvastatin induces ferroptosis, mitophagy, autophagy and apoptosis.",418.57,"79902-63-9",83,198.29,"<1",0,"http://selleckchem.com/products/Simvastatin(Zocor).html","C25H38O5","free base","MK-0733, MK 733","CCC(C)(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C12",4.634,4,1,7]
["S1793","Ramipril","d4","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;EP9.8;;BP2019;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","076549,077004,077470,077513,077514,077626,077900,078191,078745,078832,078849,079116,090650,090697,091069,091604,202392","Cardiovascular Disease/Endocrinology/Metabolic Disease","ACE,RAAS","Endocrinology & Hormones","Ramipril(HOE-498) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.",416.51,"87333-19-5",83,199.27,"<1",0,"http://selleckchem.com/products/Ramipril(Altace).html","C23H32N2O5","free base","HOE-498","CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCC3CC2C(O)=O",0.308,4,1,10]
["S1794","Fenofibrate (NSC-281319)","e4","L1300-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","076433,076509,076520,076635,090715,090856,200579,200884,201748,202856,204019,204475,204598,205118,207803,208709,209660,209950,209951,210138,210606,211080","Cardiovascular Disease","Autophagy,P450 (e.g. CYP17),PPAR","Metabolism","Fenofibrate (NSC-281319) is a compound of the fibrate class and fibric acid derivative. Fenofibrate is a selective agonist of PPARα with EC50 of 30 μM. Fenofibrate binds to and inhibits cytochrome P450 epoxygenase (CYP)2C with IC50 of 0.2 μM, 0.7 μM and 9.7 μM for CYP2C19, CYP2B6 and CYP2C9, respectively. Fenofibrate induces autophagy.",360.83,"49562-28-9",72,199.54,"<1",0,"http://selleckchem.com/products/Fenofibrate(Tricor).html","C20H21ClO4","free base","NSC-281319","CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(Cl)C=C2",5.111,4,0,7]
["S1799","Ranolazine","f4","L1300-05","in 10mM DMSO","FDA,DMF,EMA,NDC","Martindale:The Extra Pharmacopoeia","201046,208174,208862,209081,210054,211291,211707","Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Ranolazine (CVT 303, RS 43285-003) is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina.",427.54,"95635-55-5",86,201.15,"<1",0,"http://selleckchem.com/products/Ranolazine(Ranexa).html","C24H33N3O4","Free Base","CVT 303, RS 43285-003","COC1=CC=CC=C1OCC(O)CN2CCN(CC2)CC(=O)NC3=C(C)C=CC=C3C",2.991,3,2,9]
["S1801","Ranitidine Hydrochloride","g4","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.6;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","074023,074467,074488,074552,074655,074662,074680,074764,074777,074864,075000,075094,075132,075165,075167,075180,075208,075212,075254,075294,075296,075439,075497,075519,075557,075564,075742,076124,076195,076705,076760,077405,077426,077458,077476,077602,077824,078192,078312,078448,078542,078653,078684,078701,078884,078890,079076,079211,079212,090054,090102,090623,091078,091091,091288,091429,091534,200172,200536,201745,203694,205512,207578,207579,209160,209161,209859,210010,210243,211058,211289,211893","Gastrointestinal Disease","Histamine Receptor","Neuronal Signaling","Ranitidine (AH19065) is a histamine H2-receptor antagonist, used to treat stomach or intestinal ulcers.",350.86,"66357-59-3",70,199.51,70,199.51,"http://selleckchem.com/products/Ranitidine-hydrochloride(Zantac).html","C13H22N4O3S.HCl","Hydrochloride","AH19065","Cl.CNC(/NCCSCC1=CC=C(CN(C)C)O1)=C\\[N+]([O-])=O",1.421,1,2,10]
["S1805","Acetylcholine Chloride","h4","L1300-05","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,BP2017,KP Ⅹ,JP17","016211,020213","Ophthalmology","AChR","Neuronal Signaling","The chemical compound Acetylcholine Chloride(ACh chloride) is a neurotransmitter in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans.",181.66,"60-31-1",36,198.17,36,198.17,"http://www.selleck.cn/products/Acetylcholine-chloride.html","C7H16NO2.Cl","Chloride","ACh chloride","[Cl-].CC(=O)OCC[N+](C)(C)C",-3.869,2,0,4]
["S1806","Acipimox","a5","L1300-05","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Others","Others","Acipimox (Olbemox,K-9321) is a niacin derivative used as a hypolipidemic agent.",154.12,"51037-30-0",31,201.14,"<1",0,"http://selleckchem.com/products/Acipimox.html","C6H6N2O3","free base","Olbemox,K-9321","CC1=CN=C(C=[N+]1[O-])C(O)=O",-0.975,2,0,1]
["S1807","Aciclovir (BW 248U)","b5","L1300-05","in 10mM DMSO","DMF,CFDA,PMDA,HMA","BP2019;EP9.2;Ph.Int_6th;JP17;IP2010;CP2005;EP9.1;BP2017\nUSP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Infection","Antiviral,Apoptosis related,DNA/RNA Synthesis,Nucleoside Analog/Antimetabolite","Microbiology","Acyclovir (Acyclovir, Acycloguanosine, Zovirax, ACV, NSC 645011,BW 248U) is a synthetic nucleoside analogue active against herpesviruses. Acyclovir induces cell cycle perturbation and apoptosis in Jurkat leukemia cells.",225.2,"59277-89-3",45,199.82,"<1",0,"http://selleckchem.com/products/Acyclovir(Aciclovir).html","C8H11N5O3","free base","Acyclovir, Acycloguanosine, Zovirax, ACV, NSC 645011,BW 248U","NC1=NC2=C(N=C[N]2COCCO)C(=O)N1",-1.423,4,3,4]
["S1808","Nifedipine (BAY-a-1040)","c5","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","072409,072556,072579,072651,072781,073250,073421,074045,075108,075269,075289,075414,076070,077127,077899,090602,090649,201071,202644,202987,203126,210012,210184,210614,210838","Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Nifedipine (BAY-a-1040) is a dihydropyridine calcium channel blocker, used to lower hypertension and to treat angina.",346.33,"21829-25-4",69,199.23,"<1",0,"http://selleckchem.com/products/Nifedipine(Adalat).html","C17H18N2O6","free base","BAY-a-1040","COC(=O)C1=C(C)NC(=C(C1C2=C(C=CC=C2)[N+]([O-])=O)C(=O)OC)C",1.766,4,1,6]
["S1811","Amiloride (MK-870) HCl","d5","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;EP9.7;BP2019;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","070346,079133,204180","Cardiovascular Disease/Metabolic Disease","Calcium Channel,Serine Protease,Sodium Channel","Transmembrane Transporters","Amiloride (MK-870 HCl) is a selective T-type calcium channel blocker, an epithelial sodium channel blocker and a selective inhibitor of urokinase plasminogen activator (uPA)(Ki=7 μM).",266.09,"2016-88-8",53,199.18,6,22.55,"http://selleckchem.com/products/Amiloride-hydrochloride(Midamor).html","C6H8ClN7O.HCl","Hydrochloride","MK-870 HCl","Cl.NC(=N)NC(=O)C1=NC(=C(N)N=C1N)Cl",-0.366,3,4,2]
["S1813","Amlodipine Besylate","e5","L1300-05","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","022026,076418,076692,076719,076846,076859,077073,077080,077262,077333,077362,077516,077671,077759,077771,077955,077974,078021,078043,078081,078131,078224,078226,078231,078414,078453,078477,078500,078552,078573,078925,090752,201380,202553,203245,204900,206367,206524,207821","Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Amlodipine Besylate is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.",567.05,"111470-99-6",113,199.28,"<1",0,"http://selleckchem.com/products/Amlodipine-besylate(Norvasc).html","C20H25ClN2O5.C6H6O3S","Besylate","N/A","CCOC(=O)C1=C(COCCN)NC(=C(C1C2=C(Cl)C=CC=C2)C(=O)OC)C.O[S](=O)(=O)C3=CC=CC=C3",2.739,5,2,11]
["S1816","Chlorpheniramine Maleate","f5","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;KP Ⅹ;JP17;IP2010","040829,070797,080626,080696,080700,080779,080786,080791,080797,080809,080821,080938,080961,083062,083078,083243,083593,083753,083787,085104,085139,085837,086095,086096,086306,086519,086941,087164,087520,088556","Immunology/Inflammation","Histamine Receptor","Neuronal Signaling","Chlorpheniramine Maleate (Chlorpheniramine maleate, Chlorphenamine, NCI-C55265) is an histamine H1 receptor antagonist with IC50 of 12 nM.",390.86,"113-92-8",78,199.56,78,199.56,"http://selleckchem.com/products/Chlorpheniramine-maleate.html","C16H19ClN2.C4H4O4","Maleate","NCI-C55265","CN(C)CCC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.OC(=O)\\C=C/C(O)=O",0.7,3,0,7]
["S1820","Clofibrate","g5","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,PMDA","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,KP Ⅹ,JP17,BP2017","070531,071603,072191,072600,073396","Cardiovascular Disease","Others","Others","Clofibrate (Atromid-S), a fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia.",242.7,"637-07-0",7,28.84,"<1",0,"http://www.selleck.cn/products/Clofibrate(Atromid-S).html","C12H15ClO3","Free Base",0,"CCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1",3.329,3,0,5]
["S1823","Fenoprofen Calcium","h5","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia","071738,072165,072194,072214,072267,072274,072293,072294,072307,072308,072309,072326,072355,072356,072357,072362,072394,072395,072396,072407,072429,072437,072438,072472,072557,072602,072902,072946,072981,072982","Immunology/Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.",522.6,"34597-40-5",105,200.92,"<1",0,"http://selleckchem.com/products/fenoprofen-calcium.html","C30H26CaO6","Calcium salt","N/A","[Ca++].CC(C([O-])=O)C1=CC(=CC=C1)OC2=CC=CC=C2.CC(C([O-])=O)C3=CC(=CC=C3)OC4=CC=CC=C4",4.086,2,0,8]
["S1825","Erdosteine","a6","L1300-05","in 10mM DMSO","CFDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Inflammation","NF-κB","NF-κB","Erdosteine (KW-9144,RV 144) is a mucolytic which is used in treatment of excessive viscous mucus. Erdosteine inhibits lipopolysaccharide (LPS)-induced NF-κB activation.",249.31,"84611-23-4",50,200.55,"<1",0,"http://selleckchem.com/products/erdosteine.html","C8H11NO4S2","free base","KW-9144,RV 144","OC(=O)CSCC(=O)NC1CCSC1=O",-0.382,3,1,5]
["S1827","Betaxolol HCl","b6","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","075386,075446,075541,075630,078694,078962","Cardiovascular Disease/Ophthalmology","Adrenergic Receptor","Neuronal Signaling","Betaxolol (SL 75212) is a β1 adrenergic receptor blocker with IC50 of 6 μM.",343.89,"63659-19-8",69,200.65,69,200.65,"http://selleckchem.com/products/betaxolol-hydrochloride-betoptic.html","C18H29NO3.HCl","Hydrochloride","SL 75212 HCl","Cl.CC(C)NCC(O)COC1=CC=C(CCOCC2CC2)C=C1",2.959,2,2,11]
["S1828","Proparacaine HCl","c6","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37","040074,040277,084144,084151","Neurological Disease","Sodium Channel","Transmembrane Transporters","Proparacaine HCl(Proxymetacaine Hydrochloride) is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM.",330.85,"5875-06-9",12,36.27,66,199.49,"http://selleckchem.com/products/proparacaine-hcl.html","C16H26N2O3.HCl","Hydrochloride","Proxymetacaine Hydrochloride","Cl.CCCOC1=C(N)C=C(C=C1)C(=O)OCCN(CC)CC",3.013,3,1,10]
["S1829","Pranlukast","d6","L1300-05","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Immunology","Immunology & Inflammation related","Immunology & Inflammation","Pranlukast (ONO-1078,ono-rs-411) is an orally administered, and selective antagonist of the cysteinyl leukotrienes (LT) C(4), LTD(4) and LTE(4), used in the prophylactic treatment of chronic bronchial asthma.",481.5,"103177-37-3",11,22.85,"<1",0,"http://selleckchem.com/products/pranlukast.html","C27H23N5O4","free base","ONO-1078,ono-rs-411","O=C(NC1=CC2=C(C=C1)C(=O)C=C(O2)C3=NN=N[NH]3)C4=CC=C(OCCCCC5=CC=CC=C5)C=C4",4.232,7,2,9]
["S1830","Oxfendazole","e6","L1300-05","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.8;IP2010;Martindale:The Extra Pharmacopoeia",null,"Infection","Parasite","Microbiology","Oxfendazole (RS-8858,Fenbendazole sulfoxide) is a broad spectrum benzimidazole anthelmintic.",315.35,"53716-50-0",10,31.71,"<1",0,"http://selleckchem.com/products/oxfendazole.html","C15H13N3O3S","free base","RS-8858,Fenbendazole sulfoxide","COC(=O)NC1=NC2=C([NH]1)C=C(C=C2)[S](=O)C3=CC=CC=C3",2.657,4,2,4]
["S1831","Carvedilol","f6","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","076373,076649,076989,077316,077346,077474,077614,077780,077887,078165,078217,078227,078240,078251,078332,078384,078786","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Carvedilol (BM-14190, SKF 105517) is a non-selective beta blocker/alpha-1 blocker, used to treat congestive heart failure (CHF) and high blood pressure.",406.47,"72956-09-3",81,199.28,"<1",0,"http://selleckchem.com/products/carvedilol.html","C24H26N2O4","free base","BM-14190, SKF 105517","COC1=CC=CC=C1OCCNCC(O)COC2=C3C(=CC=C2)[NH]C4=C3C=CC=C4",4.014,3,3,10]
["S1832","Atracurium Besylate","g6","L1300-05","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;KP Ⅹ","074632,074740,074753,074784,074824,074901,074945,090761,091489,206011,206096","Neurological Disease","AChR","Neuronal Signaling","Atracurium Besylate (BW 33A, 51W89) is a neuromuscular blocking agent with ED95 of 0.2 mg/kg.",1243.48,"64228-81-5",100,80.42,33,26.54,"http://selleckchem.com/products/atracurium-besylate.html","C53H72N2O12.2(C6H5O3S)","Dibesylate","BW 33A, 51W89","COC1=CC=C(CC2C3=CC(=C(OC)C=C3CC[N+]2(C)CCC(=O)OCCCCCOC(=O)CC[N+]4(C)CCC5=CC(=C(OC)C=C5C4CC6=CC=C(OC)C(=C6)OC)OC)OC)C=C1OC.[O-][S](=O)(=O)C7=CC=CC=C7.[O-][S](=O)(=O)C8=CC=CC=C8",3.646,12,0,28]
["S1833","Butoconazole nitrate","h6","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","019881","Infection","Fungal,IFN,Interleukins,TNF-alpha","Microbiology","Butoconazole nitrate (RS-35887) is an anti-fungal agent that inhibits PHA-stimulated release of cytokines-- IL-2, TNFα, IFN and GM-CSF from human peripheral blood lymphocytes (IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively).",474.79,"64872-77-1",95,200.09,"<1",0,"http://selleckchem.com/products/butoconazole-nitrate.html","C19H17Cl3N2S.HNO3","Nitrate","RS-35887","O[N+]([O-])=O.ClC1=CC=C(CCC(C[N]2C=CN=C2)SC3=C(Cl)C=CC=C3Cl)C=C1",5.238,1,0,7]
["S1835","Azithromycin (CP-62993)","a7","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.3;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","050809,065150,065153,065179,065193,065209,065211,065212,065218,065223,065225,065246,065265,065297,065302,065360,065365,065366,065398,065399,065400,065404,065405,065419,065488,065500,065501,065506,065507,065508,065509,065511,090923,202308,202793,203294,203412,204732,205666,207370,207398,207531,207566,208249,208250,209043,209044,209045,209201,209999,210000,210001,211147","Infection/Parasitology","Antibiotics,Antibiotics for Mammalian Cell Culture,Autophagy,Bacterial,COVID-19","Autophagy","Azithromycin (CP-62993, XZ-450) is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.",748.98,"83905-01-5",100,133.51,"<1",0,"http://selleckchem.com/products/azithromycin-zithromax.html","C38H72N2O12","Free Base","XZ-450,CP-62993","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)CN(C)C(C)C(O)C1(C)O",2.078,7,3,7]
["S1836","Albendazole Oxide","b7","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.4;BP2019;KP Ⅹ;Ph.Int_6th;Martindale:The Extra Pharmacopoeia","208094,208979,210011,210434,211117","Infection","Microtubule Associated","Cytoskeletal Signaling","Albendazole Oxide (Ricobendazole,Albendazole sulfoxide) is a tubulin polymerization or assembly inhibitor, used for the treatment of a variety of parasitic worm infestations.",281.33,"54029-12-8",11,39.1,"<1",0,"http://selleckchem.com/products/albendazole-oxide-ricobendazole.html","C12H15N3O3S","free base","Ricobendazole,Albendazole sulfoxide","CCC[S](=O)C1=CC2=C(C=C1)N=C(NC(=O)OC)[NH]2",1.953,4,2,5]
["S1839","Chloroxine","c7","L1300-05","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia","017594","Infection/Inflammation","Bacterial","Microbiology","Chloroxine is a synthetic antibacterial compound that is effective in the treatment of dandruff and seborrheic dermatitis when incorporated in a shampoo.",214.05,"773-76-2",43,200.89,"<1",0,"http://selleckchem.com/products/Chloroxine.html","C9H5Cl2NO","free base","N/A","OC1=C(Cl)C=C(Cl)C2=C1N=CC=C2",3.103,1,1,0]
["S1840","Lomustine","d7","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","017588","Cancer","DNA/RNA Synthesis","DNA Damage/DNA Repair","Lomustine (NSC79037, Gleostine, CeeNU, CCNU) inhibits cancer cells by damaging the DNA and stops cells from dividing.",233.7,"13010-47-4",46,196.83,"<1",0,"http://selleckchem.com/products/Lomustine(CeeNU).html","C9H16ClN3O2","free base","NSC79037, Gleostine, CeeNU, CCNU","ClCCN(N=O)C(=O)NC1CCCCC1",2.394,2,1,4]
["S1843","Chenodeoxycholic Acid","e7","L1300-05","in 10mM DMSO","DMF,EMA,CFDA,PMDA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia",null,"Gastroenterology","FXR","Metabolism","Chenodeoxycholic Acid (Chenodiol, Chenodesoxycholic acid, Chenocholic acid,CDCA) is a naturally occurring human bile acid, and inhibits production of cholesterol in the liver and absorption in the intestines. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.",392.57,"474-25-9",79,201.24,"<1",0,"http://selleckchem.com/products/Chenodeoxycholic-acid.html","C24H40O4","free base","Chenodiol, Chenodesoxycholic acid, Chenocholic acid,CDCA","CC(CCC(O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C",4.014,1,2,4]
["S1845","Cimetidine","f7","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.4;BP2019;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","074100,074151,074246,074250,074316,074329,074339,074340,074349,074361,074365,074371,074401,074402,074424,074463,074506,074566,074568,074890,074948,074961,074963,074972,075122,075285,075345,075425","Gastrointestinal Disease","Histamine Receptor","Neuronal Signaling","Cimetidine (SKF-92334), a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.",252.34,"51481-61-9",51,202.11,"<1",0,"http://selleckchem.com/products/Cimetidine(Tagamet).html","C10H16N6S","free base","SKF-92334","CNC(NCCSCC1=C(C)[NH]C=N1)=NC#N",0.007,2,3,7]
["S1847","Clemastine (HS-592) fumarate","g7","L1300-05","in 10mM DMSO","FDA,NDC,PMDA","USP42-NF37;EP9.3;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","073095,073282,073283,073399,073458,073459,074075,074512,074863,074884,075703","Inflammation","Autophagy,Histamine Receptor,mTOR","Neuronal Signaling","Clemastine Fumarate (HS-592, Meclastine) is a selective histamine H1 receptor antagonist with IC50 of 3 nM. Clemastine stimulates autophagy via mTOR pathway.",459.96,"14976-57-9",35,76.09,"<1",0,"http://selleckchem.com/products/Clemastine-Fumarate.html","C21H26ClNO.C4H4O4","Fumarate","HS-592 fumarate, Meclastine fumarate","CN1CCCC1CCOC(C)(C2=CC=CC=C2)C3=CC=C(Cl)C=C3.OC(=O)\\C=C\\C(O)=O",1.81,3,0,8]
["S1848","Curcumin","h7","L1300-05","in 10mM DMSO","DMF","EP8.8;BP2016;IP2010;Martindale:The Extra Pharmacopoeia;CP2005",null,"Cancer/Inflammation/Psychotic disorders","Apoptosis related,Autophagy,Epigenetic Reader Domain,Ferroptosis,HCV,HDAC,Histone Acetyltransferase,HIV,Influenza Virus,NF-κB,Nrf2","Epigenetics","Curcumin (Diferuloylmethane, Natural Yellow 3, Turmeric yellow) is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase（IC50~25 μM）and Histone deacetylase (HDAC); activates Nrf2 pathway and supresses the activation of NF-κB. Curcumin induces mitophagy, autophagy, apoptosis, and cell cycle arrest with antitumor activity. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus, hepatitis C virus, HIV and so on.",368.38,"458-37-7",73,198.16,"<1",0,"http://selleckchem.com/products/Curcumin.html","C21H20O6","free base","Diferuloylmethane, Natural Yellow 3, Turmeric yellow","COC1=CC(=CC=C1O)/C=C/C(O)=C/C(=O)/C=C/C2=CC(=C(O)C=C2)OC",3.573,3,3,7]
["S1849","Daidzein","a8","L1300-05","in 10mM DMSO","CFDA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease/Endocrinology","PPAR","Metabolism","Daidzein is a natural isoflavone phytoestrogen found in Leguminosae, used as a component of foods and dietary supplements. Daidzein is a soy isoflavone, which acts as a PPAR activator.",254.24,"486-66-8",51,200.6,"<1",0,"http://selleckchem.com/products/Daidzein.html","C15H10O4","free base","N/A","OC1=CC=C(C=C1)C2=COC3=CC(=CC=C3C2=O)O",2.382,2,2,1]
["S1854","Bifonazole","b8","L1300-05","in 10mM DMSO","DMF,CFDA,PMDA,HMA","BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia",null,"Infection","Fungal","Microbiology","Bifonazole (Bay h 4502,(±)-bifonazole) is a substituted imidazole antifungal agent.",310.39,"60628-96-8",62,199.75,"<1",0,"http://selleckchem.com/products/bifonazole.html","C22H18N2","free base","Bay h 4502,(±)-bifonazole","C1=CC=C(C=C1)C([N]2C=CN=C2)C3=CC=C(C=C3)C4=CC=CC=C4",4.637,1,0,4]
["S1855","Pefloxacin Mesylate","c8","L1300-05","in 10mM DMSO","CFDA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia;CP2005",null,"Infection","Bacterial","Microbiology","Pefloxacin Mesylate(Pefloxacinium mesylate) is a synthetic chemotherapeutic agent and an antibacterial agent with IC50 of 6.7 nM.",429.46,"70458-95-6",14,32.6,67,156.01,"http://selleckchem.com/products/pefloxacin-mesylate.html","C17H20FN3O3.CH4O3S","Mesylate","Pefloxacinium mesylate","CCN1C=C(C(O)=O)C(=O)C2=CC(=C(C=C12)N3CCN(C)CC3)F.C[S](O)(=O)=O",-1.618,2,0,3]
["S1856","Metoprolol Tartrate","d8","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","073288,073289,073654,073666,074032,074133,074141,074143,074217,074258,074333,074380,074453,074644,075160,076495,076670,076704,077360,077739,077761,078085,078459,078950,090317,090386,091045,091307,200981,202871,204205","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Metoprolol Tartrate (CGP 2175E) is a selective β1 receptor blocker medication, used to treat hypertension and heart failure.",684.81,"56392-17-7",100,146.03,100,146.03,"http://selleckchem.com/products/metoprolol-tartrate.html","2C15H25NO3.C4H6O6","Tartrate","CGP 2175E","COCCC1=CC=C(OCC(O)CNC(C)C)C=C1.COCCC2=CC=C(OCC(O)CNC(C)C)C=C2.OC(C(O)C(O)=O)C(O)=O",-3.559,6,6,21]
["S1858","Dienestrol","e8","L1300-05","in 10mM DMSO","FDA","EP7.5;USP39-NF34;IP2010;Martindale:The Extra Pharmacopoeia","006110","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Dienestrol(Restrol) is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist.",266.33,"84-17-3",53,199,-1,0,"http://www.selleckchem.com/products/Dienestrol(Restrol).html","C18H18O2","Free Base","Restrol","C/C=C(C1=CC=C(O)C=C1)/C(=C/C)C2=CC=C(O)C=C2",4.692,0,2,3]
["S1859","Diethylstilbestrol","f8","L1300-05","in 10mM DMSO","FDA,DMF,CFDA","USP42-NF37;BP2019;EP9.2;CP2005;Martindale:The Extra Pharmacopoeia","004039,004040,004041","Cancer","Estrogen/progestogen Receptor","Endocrinology & Hormones","Diethylstilbestrol (Stilbestrol) is a synthetic nonsteroidal estrogen, used to prevent miscarriage and other pregnancy complications.",268.35,"56-53-1",54,201.23,"<1",0,"http://selleckchem.com/products/Diethylstilbestrol(Stilbestrol).html","C18H20O2","free base","Stilbestrol","CCC(/C1=CC=C(O)C=C1)=C(CC)\\C2=CC=C(O)C=C2",5.137,0,2,4]
["S1865","Diltiazem HCl","g8","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","020939,072838,074051,074067,074079,074084,074093,074168,074185,074617,074845,074852,074894,074910,074941,074943,074984,075004,075086,075106,075116,075124,075375,075749,075853,076563,077686,078538,090421,090492,091022,202463,202651,203023,205231,206534,206641,209766","Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Diltiazem (Tiazac, RG 83606) HCl is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions.",450.98,"33286-22-5",90,199.57,90,199.57,"http://selleckchem.com/products/Diltiazem-HCl(Tiazac).html","C22H26N2O4S.HCl","Hydrochloride","RG 83606 HCl","Cl.COC1=CC=C(C=C1)C2SC3=C(C=CC=C3)N(CCN(C)C)C(=O)C2OC(C)=O",3.475,4,0,7]
["S1866","Diphenhydramine HCl","h8","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia;CP2005","040140,040466,040498,070497,072416,073611,080519,080577,080592,080596,080635,080643,080727,080728,080738,080762,080800,080807,080817,080822,080832,080845,080868,080873,080939,083027,083061,083063,083087,083088,083183,083237,083275,083441,083533,083567,083634,083674,083797,083953,084506,084524,085083,085138,085150,085156,085287,085621,085701,085874,086543,086544,086874,086875,086937,087066,087513,087630,087914,087941,087977,087978,088034,088680,088880,089040,089041,089101,089488,089489,205723","Immunology/Neurological Disease","Histamine Receptor","Neuronal Signaling","Diphenhydramine HCl is a first-generation histamine H1 receptor antagonist, used in various allergic conditions such as rhinitis, urticaria and conjunctivitis.",291.82,"147-24-0",58,198.75,58,198.75,"http://selleckchem.com/products/Diphenhydramine-hydrochloride(Benadryl).html","C17H21NO.HCl","Hydrochloride","N/A","Cl.CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2",3.766,1,0,6]
["S1869","Dapoxetine HCl","a9","L1300-05","in 10mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia",null,"Others","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Dapoxetine HCl (LY-210448) is a short-acting novel selective serotonin reuptake inhibitor, used for the treatment of premature ejaculation.",341.87,"129938-20-1",68,198.91,68,198.91,"http://selleckchem.com/products/Dapoxetine-hydrochloride(Priligy).html","C21H23NO.HCl","Hydrochloride","LY-210448","Cl.CN(C)C(CCOC1=C2C=CC=CC2=CC=C1)C3=CC=CC=C3",4.917,1,0,6]
["S1876","Valaciclovir HCl","b9","L1300-05","in 10mM DMSO","DMF,CFDA,PMDA,HMA","EP9.8;BP2019;JP17;Martindale:The Extra Pharmacopoeia",null,"Infection","CMV","Microbiology","Valaciclovir HCl, an aciclovir prodrug, inhibits activity of virus DNA polymerase, used to treat infections caused by herpes simplex virus (HSV) and varicella zoster virus, and for prophylaxis against cytomegalovirus (CMV).",360.8,"124832-27-5",14,38.8,72,199.56,"http://selleckchem.com/products/valaciclovir-hcl.html","C13H20N6O4.HCl","Hydrochloride","N/A","Cl.CC(C)C(N)C(=O)OCCOC[N]1C=NC2=C1N=C(N)NC2=O",-0.296,6,3,8]
["S1878","Ganciclovir (BW 759)","c9","L1300-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP41-NF36;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia;CP2005","076457,090658,202624,204204,204560,204950,209347","Infection","CMV","Microbiology","Ganciclovir (RS-21592, BW-759, 2'-Nor-2'-deoxyguanosine) is an antiviral drug for feline herpesvirus type-1 with IC50 of 5.2 μM in a cell-free assay.",255.23,"82410-32-0",27,105.79,"<1",0,"http://selleckchem.com/products/ganciclovir.html","C9H13N5O4","free base","RS-21592, BW-759, 2'-Nor-2'-deoxyguanosine","NC1=NC2=C(N=C[N]2COC(CO)CO)C(=O)N1",-1.934,4,4,5]
["S1880","Roxatidine Acetate HCl","d9","L1300-05","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Gastroenterology","Histamine Receptor","Neuronal Signaling","Roxatidine Acetate HCl(HOE 760) is a specific and competitive histamin H2-receptor antagonist, with IC50 of 3.2 μM, inhibits gastric acid secretion and ulcer formation.",384.9,"93793-83-0",77,200.05,77,200.05,"http://selleckchem.com/products/roxatidine-acetate-hcl.html","C19H28N2O4.HCl","Hydrochloride","HOE 760","Cl.CC(=O)OCC(=O)NCCCOC1=CC=CC(=C1)CN2CCCCC2",2.148,4,1,10]
["S1881","Protionamide","e9","L1300-05","in 10mM DMSO","CFDA","Ph.Int_6th;Martindale:The Extra Pharmacopoeia",null,"Infection","Bacterial","Microbiology","Protionamide (Prothionamide, 1321-TH) is a drug used in the treatment of tuberculosis.",180.27,"14222-60-7",36,199.7,"<1",0,"http://selleckchem.com/products/protionamide-prothionamide.html","C9H12N2S","free base","Prothionamide, 1321-TH","CCCC1=NC=CC(=C1)C(N)=S",1.954,1,1,3]
["S1883","Idoxuridine","f9","L1300-05","in 10mM DMSO","FDA,DMF,CFDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","014169,013935,013934,015868","Infection","Antiviral","Microbiology","Idoxuridine (NSC 39661, SKF 14287,5-Iodo-2′-deoxyuridine,5-IUdR,IdUrd) is an antiviral agent for feline herpesvirus type-1 with IC50 of 4.3 μM.",354.1,"54-42-2",35,98.84,"<1",0,"http://selleckchem.com/products/idoxuridine.html","C9H11IN2O5","free base","NSC 39661, SKF 14287,5-Iodo-2′-deoxyuridine,5-IUdR,IdUrd","OCC1OC(CC1O)N2C=C(I)C(=O)NC2=O",-1.402,3,3,2]
["S1884","Sparfloxacin","g9","L1300-05","in 10mM DMSO","FDA,CFDA","Martindale:The Extra Pharmacopoeia;CP2005","020677","Infection","Antibiotics,Bacterial","Microbiology","Sparfloxacin (AT-4140, CI-978, PD 131501,Zagam) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity.",392.4,"110871-86-8",9,22.94,"<1",0,"http://selleckchem.com/products/sparfloxacin.html","C19H22F2N4O3","free base","AT-4140, CI-978, PD 131501,Zagam","CC1CN(CC(C)N1)C2=C(F)C3=C(C(=C2F)N)C(=O)C(=CN3C4CC4)C(O)=O",-1.056,2,2,3]
["S1885","Felodipine","h9","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia;CP2005","075896,078855,090365,091200,091484,200815,201964,202170,203032,203417,203983,204800,210847","Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Felodipine (CGH-869) is a selective L-type Ca2+ channel blocker with IC50 of 0.15 nM.",384.25,"72509-76-3",77,200.39,"<1",0,"http://selleckchem.com/products/Felodipine(Plendil).html","C18H19Cl2NO4","free base","CGH-869","CCOC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2Cl)Cl)C(=O)OC)C",3.549,4,1,6]
["S1888","Deflazacort","a10","L1300-05","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","208684,208685","Immunology/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Deflazacort (MDL 458) is a glucocorticoid used as an anti-inflammatory and immunosuppressant.",441.52,"14484-47-0",88,199.31,"<1",0,"http://selleckchem.com/products/Deflazacor.html","C25H31NO6","free base","MDL 458","CC(=O)OCC(=O)C12N=C(C)OC1CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC23C",1.67,6,1,4]
["S1890","Nizatidine","b10","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","075461,075616,075668,075806,075934,076178,076383,077314,090576,090618","Gastrointestinal Disease","Histamine Receptor","Neuronal Signaling","Nizatidine is a histamine H2 receptor antagonist with IC50 of 0.9 nM, also inhibits AChE with IC50 of 6.7 μM.",331.46,"76963-41-2",66,199.12,28,84.47,"http://selleckchem.com/products/Nizatidine(Axid).html","C12H21N5O2S2","free base","N/A","CNC(/NCCSCC1=CSC(=N1)CN(C)C)=C/[N+]([O-])=O",0.643,1,2,10]
["S1891","Carbidopa","c10","L1300-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","203261,204291,204763,205304,209910","Neurological Disease","Decarboxylase","Metabolism","Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM.",226.23,"28860-95-9",4,17.68,"<1",0,"http://selleckchem.com/products/Carbidopa.html","C10H14N2O4","free base","N/A","CC(CC1=CC(=C(O)C=C1)O)(NN)C(O)=O",0.364,1,4,4]
["S1894","Valsartan (CGP-48933)","d10","L1300-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","077492,077530,090642,090866,091367,201677,202223,202696,202728,203311,203536,204011,204821,205347,205357,205536,209261","Cardiovascular Disease","Angiotensin Receptor","GPCR & G Protein","Valsartan (CGP-48933) is a selective angiotensin II receptor antagonist, used to treat high blood pressure and congestive heart failure.",435.52,"137862-53-4",87,199.76,"<1",0,"http://selleckchem.com/products/Valsartan(Diovan).html","C24H29N5O3","free base","CGP-48933","CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=N[NH]N=N3)C(C(C)C)C(O)=O",4.538,5,1,10]
["S1895","Dipyridamole (NSC 515776)","e10","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","040542,040733,040782,040874,040898,074521,074601,074939,074952,074956,075769,086944,087160,087184,087561,087562,087716,087717,088999,089000,089001,089425,089426,089427","Cardiovascular Disease","PDE","Metabolism","Dipyridamole (NSC-515776, Persantine) is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells.",504.63,"58-32-2",101,200.15,"<1",0,"http://selleckchem.com/products/Dipyridamole(Permole,-Persantine).html","C24H40N8O4","free base","Persantine,NSC-515776","OCCN(CCO)C1=NC2=C(N=C(N=C2N3CCCCC3)N(CCO)CCO)C(=N1)N4CCCCC4",2.483,4,4,12]
["S1896","Hydroxyurea (NSC-32065)","f10","L1300-05","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;BP2015","074476,075020,075143,075340,075734","Cancer/Hematology","Apoptosis related,Autophagy,DNA/RNA Synthesis,HIV","DNA Damage/DNA Repair","Hydroxyurea (NSC-32065, NCI-C04831, Hydroxycarbamide) is an antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase. Hydroxyurea activates apoptosis and autophagy. Hydroxyurea is used to treat HIV infection.",76.05,"127-07-1",15,197.24,15,197.24,"http://selleckchem.com/products/Hydroxyurea(Cytodrox).html","CH4N2O2","free base","NCI-C04831, Hydroxycarbamide,NSC-32065","NC(=O)NO",-1.03,1,2,0]
["S1897","Potassium Iodide","g10","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","018551,206211","Endocrinology","Others","Others","Potassium Iodide is used to treat overactive thyroid and to protect the thyroid gland from the effects of radiation from inhaled or swallowed radioactive iodine.",166,"7681-11-0",33,198.8,33,198.8,"http://selleckchem.com/products/Potassium-iodide.html","K+I-","Inorganic salt","N/A","[K+].[I-]",-3.113,0,0,0]
["S1898","Tropisetron HCl","h10","L1300-05","in 10mM DMSO","CFDA,HMA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Gastroenterology","5-HT Receptor","Neuronal Signaling","Tropisetron HCl (ICS 205-930) is a potent and selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist, used to treat nausea and vomiting following chemotherapy.",320.81,"105826-92-4",35,109.1,46,143.39,"http://selleckchem.com/products/Tropisetron-hydrochloride.html","C17H20N2O2.HCl","Hydrochloride","ICS 205-930","Cl.CN1C2CCC1CC(C2)OC(=O)C3C=NC4=CC=CC=C34",2.366,3,0,3]
["S1899","Nicotinamide (NSC 13128)","a11","L1300-05","in 10mM DMSO","DMF,CFDA,NDC,PMDA,HMA","KP Ⅹ;EP9.1;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia",null,"Inflammation/Cardiovascular Disease","Sirtuin","DNA Damage/DNA Repair","Nicotinamide (Niacinamide, Vitamin PP, Nicotinic acid amide, Vitamin B3, NSC 27452,NSC 13128), a water-soluble vitamin, is an active component of coenzymes NAD and NADP, and also act as an inhibitor of sirtuins.",122.12,"98-92-0",24,196.53,24,196.53,"http://selleckchem.com/products/Nicotinamide(Niacinamide).html","C6H6N2O","free base","Niacinamide, Vitamin PP, Nicotinic acid amide, Vitamin B3, NSC 27452,NSC 13128","NC(=O)C1=CC=CN=C1",-0.319,2,1,1]
["S1902","Vitamin B12","b11","L1300-05","in 10mM DMSO","DMF,CFDA,NDC","USP39-NF34",null,"Metabolic Disease/Inflammation/Neurological Disease","Vitamin","Metabolism","Vitamin B12 (Cobalamin, Cyanocobalamin) is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.",1355.37,"68-19-9",75,55.34,6,4.43,"http://selleckchem.com/products/Vitamin-B12.html","C63H88CoN14O14P","free base","Cobalamin, Cyanocobalamin","CC(CNC(=O)CCC1(C)C(CC(N)=O)C2N=C1/C(=C/3N=C(/C=C/4N=C(/C(=C/5[N-]C2(C)C(C)(CC(N)=O)C5CCC(N)=O)C)C(C)(CC(N)=O)C4CCC(N)=O)C(C)(C)C3CCC(N)=O)C)O[P]([O-])(=O)OC6C(O)C(OC6CO)[N]7C=NC8=C7C=C(C)C(=C8)C.[Co++]C#N",-1.129,14,9,26]
["S1903","Diclofenac Sodium","c11","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","020809,074376,074390,074391,074394,074432,074459,074514,074723,074986,075185,075281,075492,075910,076152,076201,077600,077845,077863,078031,078553,078792,090066,200936,202027,202393,202769,202852,203383,203786,203818,204132,204306,205878,206116,206298,206411,206493,206715,207238,208021,208068,208077,208098,208198,208301,208786,209484,209903,210893,211253","Inflammation","COX","Neuronal Signaling","Diclofenac Sodium (GP 45840) is a non-selective COX inhibitor with IC50 of 0.5 μg/ml and 0.5 μg/ml for COX-1 and -2 in intact cells, respectively, used as a nonsteroidal anti-inflammatory drug (NSAID) to relieve pain and reduce swelling in flammation.",318.13,"15307-79-6",64,201.18,14,44.01,"http://selleckchem.com/products/Diclofenac-sodium.html","C14H10Cl2NNaO2","Sodium Salt","GP 45840","[Na+].[O-]C(=O)CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1",2.899,0,1,4]
["S1904","Avobenzone","d11","L1300-05","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","021471,022009,021502,021501,020045","Others","Others","Others","Avobenzone (Butyl methoxydibenzoylmethane, BF2AVB) is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative.",310.39,"70356-09-1",62,199.75,"<1",0,"http://selleckchem.com/products/Avobenzone(Parsol-1789).html","C20H22O3","free base","Butyl methoxydibenzoylmethane, BF2AVB","COC1=CC=C(C=C1)C(=O)CC(=O)C2=CC=C(C=C2)C(C)(C)C",4.538,3,0,6]
["S1905","Amlodipine","e11","L1300-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","022026,076418,076692,076719,076846,076859,077073,077080,077262,077333,077362,077516,077671,077759,077771,077955,077974,078021,078043,078081,078131,078224,078226,078231,078414,078453,078477,078500,078552,078573,078925,090752,201380,202553,203245,204900,206367,206524,207821","Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Amlodipine (UK-48340) is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.",408.88,"88150-42-9",82,200.55,"<1",0,"http://selleckchem.com/products/Amlodipine(Norvasc).html","C20H25ClN2O5","free base","UK-48340","CCOC(=O)C1=C(COCCN)NC(=C(C1C2=C(Cl)C=CC=C2)C(=O)OC)C",1.576,5,2,10]
["S1907","Metronidazole","f11","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia;IP2010","018517,018599,018620,018740,018764,018818,018845,018889,018907,018930,019029,070004,070008,070009,070021,070027,070033,070035,070039,070040,070042,070044,070071,070170,070593,070772,076408,076462,076505,076519,076522,077018,077197,077264,077547,077549,077819,078178,079065,079067,090222,090903,203458,203974,204651,205245,206560,207309,208162,208681,209096,209794","Infection","Antineoplastic and Immunosuppressive Antibiotics,DNA/RNA Synthesis","DNA Damage/DNA Repair","Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa.",171.15,"443-48-1",34,198.66,"<1",0,"http://selleckchem.com/products/Metronidazole(Flagyl).html","C6H9N3O3","free base","N/A","CC1=NC=C([N]1CCO)[N+]([O-])=O",-0.337,1,1,3]
["S1908","Flutamide","g11","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","075298,075780,075818,075820,076224","Cancer","Androgen Receptor","Endocrinology & Hormones","Flutamide (SCH-13521) is an antiandrogen drug, with its active metablolite binding at androgen receptor with Ki values of 55 nM, and primarily used to treat prostate cancer.",276.21,"13311-84-7",55,199.12,"<1",0,"http://selleckchem.com/products/Flutamide(Eulexin).html","C11H11F3N2O3","free base","SCH-13521","CC(C)C(=O)NC1=CC(=C(C=C1)[N+]([O-])=O)C(F)(F)F",2.916,1,1,4]
["S1909","Fluvastatin (XU-62-320) Sodium","h11","L1300-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","078407,078872,079011,090595,202458","Cardiovascular Disease","HMG-CoA Reductase","Metabolism","Fluvastatin Sodium (Vastin,XU-62-320) inhibits HMG-CoA reductase activity with IC50 of 8 nM in a cell-free assay.",433.45,"93957-55-2",87,200.72,1,2.31,"http://selleckchem.com/products/Fluvastatin-Sodium(Lescol).html","C24H25FNNaO4","Sodium","Vastin,XU-62-320","[Na+].CC(C)[N]1C2=C(C=CC=C2)C(=C1\\C=C\\C(O)CC(O)CC([O-])=O)C3=CC=C(F)C=C3",2.77,0,2,8]
["S1910","Tioconazole","a2","L1300-06","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","075915","Infection","Fungal","Microbiology","Tioconazole (UK-20349) is an antifungal medication with an average IC50 of 1.7 μM.",387.71,"65899-73-2",78,201.18,"<1",0,"http://selleckchem.com/products/tioconazole.html","C16H13Cl3N2OS","free base","UK-20349","ClC1=CC=C(C(C[N]2C=CN=C2)OCC3=C(Cl)SC=C3)C(=C1)Cl",4.437,2,0,6]
["S1913","Tropicamide","b2","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","040064,040067,087636,087637,088447,089171,089172","Ophthalmology","AChR","Neuronal Signaling","Tropicamide(Ro 1-7683) is an anticholinergic and a muscarinic receptor subtype M4-preferring antagonist with IC50 of 8.0 nM.",284.35,"1508-75-4",57,200.46,"<1",0,"http://selleckchem.com/products/tropicamide.html","C17H20N2O2","free base","Ro 1-7683","CCN(CC1=CC=NC=C1)C(=O)C(CO)C2=CC=CC=C2",1.432,2,1,6]
["S1914","Pregnenolone","c2","L1300-06","in 10mM DMSO","DMF,CFDA,NDC","USP42-NF37",null,"Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Pregnenolone(3β-Hydroxy-5-pregnen-20-one) is an endogenous steroid hormone, used in the treatment of fatigue, Alzheimer’s disease, trauma and injuries.",316.48,"145-13-1",22,69.51,"<1",0,"http://selleckchem.com/products/pregnenolone.html","C21H32O2","free base","3β-Hydroxy-5-pregnen-20-one","CC(=O)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C",3.624,1,1,1]
["S1915","Sulfamethoxazole","d2","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia;CP2005","085053,085844,086000,086163,087189,087662","Infection","Antibiotics,Bacterial","Microbiology","Sulfamethoxazole(Ro 4-2130) is a sulfonamide bacteriostatic antibiotic with an IC50 of 2.7 μM.",253.28,"723-46-6",51,201.36,"<1",0,"http://selleckchem.com/products/Sulfamethoxazole.html","C10H11N3O3S","free base","Ro 4-2130","CC1=CC(=NO1)N[S](=O)(=O)C2=CC=C(N)C=C2",0.709,4,2,3]
["S1916","Sulfisoxazole","e2","L1300-06","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;KP Ⅹ;JP17","080082,080085,080087,080109,080142,080189,080268,080379,084031,084385,085534,085628,087332,087649","Infection","Bacterial","Microbiology","Sulfisoxazole (NU-445) is a sulfonamide antibacterial with an oxazole substituent.",267.3,"127-69-5",53,198.28,"<1",0,"http://selleckchem.com/products/Sulfisoxazole.html","C11H13N3O3S","free base","NU-445","CC1=NOC(=C1C)N[S](=O)(=O)C2=CC=C(N)C=C2",0.918,4,2,3]
["S1917","Crystal Violet","f2","L1300-06","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.2;IP2010",null,"Infection","Dyes","Others","Crystal violet(Gentian Violet) is a triarylmethane dye.",407.98,"548-62-9",82,200.99,14,34.32,"http://selleckchem.com/products/Crystal-violet.html","C25H30ClN3","quaternary-N chloride salt","Gentian Violet","[Cl-].CN(C)C1=CC=C(C=C1)C(C2=CC=C(C=C2)N(C)C)=C3C=CC(C=C3)=[N+](C)C",2.25,0,0,4]
["S1920","Haloperidol","g2","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","020074,070278,070318,070710,070713,070714,070720,070721,070722,070723,070724,070725,070726,070744,070800,070801,070802,070864,070981,070982,070983,070984,071015,071071,071072,071073,071074,071075,071076,071082,071128,071129,071130,071131,071132,071133,071156,071157,071172,071173,071177,071187,071206,071207,071208,071209,071210,071211,071212,071216,071217,071218,071219,071220,071221,071233,071234,071235,071236,071237,071255,071256,071257,071269,071328,071374,071375,071376,071571,071572,071573,071617,071722,071723,071724,071725,072113,072121,072122,072353,072516,072517,072727,072728,072729,072730,072731,072732,073037,073364,075689,075858,076035,076464,076774,076791,076828,077580,078347,091637,200742,204849","Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Haloperidol (Haldol) is an antipsychotic and butyrophenone.",375.86,"52-86-8",75,199.54,"<1",0,"http://selleckchem.com/products/Haloperidol(Haldol).html","C21H23ClFNO2","free base","N/A","OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C3=CC=C(Cl)C=C3",3.887,1,0,6]
["S1921","Phenindione","h2","L1300-06","in 10mM DMSO","FDA","BP2019;IP2010;Martindale:The Extra Pharmacopoeia","008767","Cardiovascular Disease/Respiratory Disease","Vitamin","Metabolism","Phenindione (Rectadione, phenylindandione) is an anticoagulant which functions as a Vitamin K antagonist.",222.24,"83-12-5",44,197.98,"<1",0,"http://selleckchem.com/products/Phenindione(Rectadione).html","C15H10O2","free base","Rectadione, phenylindandione","O=C1C(C2=CC=CC=C2)C(=O)C3=CC=CC=C13",2.819,2,0,1]
["S1928","Alibendol","a3","L1300-06","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Neurological Disease","Others","Others","Alibendol (EB 1856) is an antispasmodic,choleretic, and cholekinetic.",251.28,"26750-81-2",50,198.98,"<1",0,"http://selleckchem.com/products/alibendol.html","C13H17NO4","free base","EB 1856","COC1=CC(=CC(=C1O)C(=O)NCCO)CC=C",1.248,2,3,6]
["S1933","Triamcinolone","b3","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP40-NF35;BP2015;JP16;Martindale:The Extra Pharmacopoeia","083750,084020,084267,084268,084270,084286,084318,084319,084320,084340,084406,084707,084708,084709,084775,085601,085834","Immunology/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Triamcinolone is a glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated.",394.43,"124-94-7",78,197.75,"<1",0,"http://selleckchem.com/products/Triamcinolone(Aristocort).html","C21H27FO6","free base","N/A","CC12CC(O)C3(F)C(CCC4=CC(=O)C=CC34C)C1CC(O)C2(O)C(=O)CO",0.422,2,3,2]
["S1934","Nystatin (Fungicidin)","c3","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","EP9.2;Ph.Int_6th;JP17;BP2017;IP2010;Martindale:The Extra Pharmacopoeia","061965,061966,062065,062124,062129,062176,062225,062349,062402,062457,062459,062460,062472,062474,062502,062506,062509,062512,062517,062518,062524,062525,062541,062571,062613,062615,062670,062776,062832,062835,062838,062840,062876,062949,064022,064042,064142,065138,065148,065175,065183,065203,065315,065321,065422,203621,207733,207767,208581,208838,209082,209114,210532,211838","Infection","Antibiotics for Mammalian Cell Culture,Fungal","Microbiology","Nystatin(Fungicidin), which belongs to the polyene group of antimycotics, is frequently used as a topical agent in the treatment of oro-pharyngeal candidosis.",1056.24,"62997-67-5",19,17.99,"<1",0,"http://selleckchem.com/products/Nystatin(Mycostatin).html","C53H85NO20","free base","Fungicidin","CC1OC(=O)CC(O)CC(O)CC(O)CCC(O)C(O)CC2(O)CC(O)C(C(CC(OC3OC(C)C(O)C(N)C3O)/C=C/C=C/C=C/C=C/CC/C=C/C=C/C(C)C(O)C1C)O2)C(O)=O",-2.265,8,11,5]
["S1937","Isoniazid","d3","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","008428,008499,008678,040090,040648,080120,080132,080136,080153,080212,080270,080368,080401,080521,080522,080523,080936,080937,080941,081118,083060,083178,083610,083632,083633,084050,085091,085784,085790,087425,088119,088231,088235,089816,202610","Infection","Fatty Acid Synthase","Metabolism","Isoniazid is a prodrug that blocks the action of fatty acid synthase by interacting with KatG , used for the prevention and treatment of tuberculosis.",137.14,"54-85-3",27,196.88,27,196.88,"http://selleckchem.com/products/Isoniazid(Tubizid).html","C6H7N3O","free base","N/A","NNC(=O)C1=CC=NC=C1",-0.811,2,2,1]
["S1940","Levofloxacin","e3","L1300-06","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.8;JP17;IP2010;Martindale:The Extra Pharmacopoeia","021832,076276,076361,076710,076826,076890,077097,077438,077652,077700,078282,078424,078577,078767,090063,090268,090367,090722,090787,091436,091644,091678,200250,200560,200839,201043,201484,202200,202328,202590,202801,203613,204899,204968,205222,205600,205968","Infection/Inflammation","Topoisomerase","DNA Damage/DNA Repair","Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections.",361.37,"100986-85-4",24,66.41,11,30.44,"http://selleckchem.com/products/levofloxacin-levaquin.html","C18H20FN3O4","Free Base","Fluoroquinolone","CC1COC2=C(N3CCN(C)CC3)C(=CC4=C2N1C=C(C(O)=O)C4=O)F",-1.374,3,0,2]
["S1941","Enalapril Maleate","f3","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia;CP2005","075048,075178,075369,075370,075459,075472,075479,075480,075482,075483,075496,075501,075556,075583,075621,075657","Cardiovascular Disease/Endocrinology/Metabolic Disease","ACE,RAAS","Endocrinology & Hormones","Enalapril (MK-421) Maleate is an angiotensin-converting enzyme (ACE) inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure.",492.52,"76095-16-4",99,201.01,"<1",0,"http://selleckchem.com/products/Enalapril-maleate(Vasotec).html","C20H28N2O5.C4H4O4","Maleate","MK-421 Maleate","CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(O)=O.OC(=O)\\C=C/C(O)=O",-0.502,6,1,12]
["S1949","Menadione (NSC 4170)","g3","L1300-06","in 10mM DMSO","FDA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","002139","Hematology","CDK,DNA/RNA Synthesis,phosphatase","Metabolism","Menadione (NSC 4170, Vitamin K3), a fat-soluble compound, is an inhibitor of Cdc25 phosphatase and mitochondrial DNA polymerase γ (pol γ), used as a nutritional supplement.",172.18,"58-27-5",34,197.47,"<1",0,"http://selleckchem.com/products/Menadione.html","C11H8O2","free base","Vitamin K3,NSC 4170","CC1=CC(=O)C2=CC=CC=C2C1=O",2.204,2,0,0]
["S1950","Metformin HCl","h3","L1300-06","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia;CP2005","075961,075965,075967,075969,075971,075972,075973,075975,075976,075978,075979,075984,075985,076033,076038,076172,076223,076249,076269,076328,076413,076450,076496,076545,076650,076706,076756,076818,076863,076864,076869,076873,076878,076985,077060,077064,077078,077095,077113,077124,077211,077336,077711,077787,077853,077880,078170,078321,078422,078596,079118,079148,079226,090014,090295,090564,090666,090692,090888,091184,091664,200690,201991,202306,202917,203686,203755,203769,203832,205096,205330,206145,206955,207427,208880,208999,209303,209313,209674,209882,209993,211052","Cancer/Cardiovascular Disease/Endocrinology/Metabolic Disease","Autophagy,Carbohydrate Metabolism,JNK,Mitophagy,p38 MAPK","Metabolism","Metformin HCl (1,1-Dimethylbiguanide HCl) decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis). Metformin promotes mitophagy in mononuclear cells. Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153.",165.62,"1115-70-4",33,199.25,33,199.25,"http://selleckchem.com/products/Metformin-hydrochloride(Glucophage).html","C4H11N5.HCl","Hydrochloride","1,1-Dimethylbiguanide HCl","Cl.CN(C)C(=N)NC(N)=N",-0.36,0,2,3]
["S1952","Methoxsalen","a4","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","087781,202603,202687","Inflammation","P450 (e.g. CYP17)","Metabolism","Methoxsalen (Xanthotoxin, NCI-C55903) is a naturally occurring photoactive substance found in the seeds of the Ammi majus (Umbelliferae) plant, used in the diagnosis and treatment of psoriasis; A CYP2A5/6 inhibitor.",216.19,"298-81-7",43,198.9,"<1",0,"http://selleckchem.com/products/Methoxsalen(Oxsoralen).html","C12H8O4","free base","Xanthotoxin, NCI-C55903","COC1=C2OC=CC2=CC3=C1OC(=O)C=C3",2.187,4,0,1]
["S1956","Miconazole Nitrate","b4","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.7;BP2019;KP Ⅹ;Ph.Int_6th ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","073507,073508,074030,074136,074366,074395,074414,074444,074760,079114,091366","Infection","Fungal","Microbiology","Miconazole (NSC 169434) Nitrate is an imidazole antifungal agent by inhibiting ergosterol biosynthesis and inducing ROS, used to treat vaginal yeast infections.",479.14,"22832-87-7",96,200.36,"<1",0,"http://selleckchem.com/products/Miconazole-nitrate.html","C18H14Cl4N2O.HNO3","Nitrate","NSC 169434 Nitrate","O[N+]([O-])=O.ClC1=CC=C(COC(C[N]2C=CN=C2)C3=CC=C(Cl)C=C3Cl)C(=C1)Cl",4.387,2,0,6]
["S1957","Sulfamethizole","c4","L1300-06","in 10mM DMSO","FDA,DMF","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","086012,080273,008565","Infection","Bacterial","Microbiology","Sulfamethizole is a sulfathiazole antibacterial agent.",270.33,"144-82-1",54,199.76,"<1",0,"http://selleckchem.com/products/Sulfamethizole(Proklar).html","C9H10N4O2S2","free base","N/A","CC1=NN=C(N[S](=O)(=O)C2=CC=C(N)C=C2)S1",0.305,4,2,3]
["S1958","Sulbactam","d4","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","065074,065076,065176,065188,065222,065240,065241,065310,065314,065316,065403,065406,090339,090340,090349,090375,090578,090579,090646,090653,201024,201406,202197","Infection","Anti-infection","Microbiology","Sulbactam(CP45899) is a beta-lactamase inhibitor with an average IC50 of 0.8 μM.",233.24,"68373-14-8",47,201.51,47,201.51,"http://selleckchem.com/products/sulbactam.html","C8H11NO5S","free base","CP45899","CC1(C)C(N2C(CC2=O)[S]1(=O)=O)C(O)=O",-0.671,4,0,1]
["S1959","Tolfenamic Acid","e4","L1300-06","in 10mM DMSO","DMF,CFDA,HMA","EP9.8;BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia",null,"Inflammation","COX","Neuronal Signaling","Tolfenamic Acid(Clotam) is a COX-2 inhibitor with IC50 of 0.2 μM.",261.7,"13710-19-5",52,198.7,"<1",0,"http://selleckchem.com/products/tolfenamic-acid.html","C14H12ClNO2","free base","Clotam","CC1=C(Cl)C=CC=C1NC2=C(C=CC=C2)C(O)=O",4.16,1,1,3]
["S1960","Pranoprofen","f4","L1300-06","in 10mM DMSO","CFDA,PMDA","KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia",null,"Inflammation/Ophthalmology","COX,PGES","Neuronal Signaling","Pranoprofen (Pyranoprofen,Pranopulin) is a non-steroidal COX inhibitor, used as an anti-inflammatory drug in ophthalmology.",255.27,"52549-17-4",51,199.79,"<1",0,"http://selleckchem.com/products/pranoprofen.html","C15H13NO3","free base","Pyranoprofen,Pranopulin","CC(C(O)=O)C1=CC2=C(OC3=NC=CC=C3C2)C=C1",3.05,3,0,2]
["S1962","Sulphadimethoxine","g4","L1300-06","in 10mM DMSO","DMF","EP10.4, USP43-NF38",null,"Infection","Anti-infection","Microbiology","Sulphadimethoxine is a non-reducing glucuronide.",310.33,"122-11-2",62,199.79,"<1",0,"http://selleckchem.com/products/sulphadimethoxine.html","C12H14N4O4S","free base","N/A","COC1=CC(=NC(=N1)OC)N[S](=O)(=O)C2=CC=C(N)C=C2",1.358,6,2,5]
["S1964","Rimantadine","h4","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","075916,076132,076375","Infection","Influenza Virus","Microbiology","Rimantadine (Flumadine) is an anti-influenza virus drug for T. brucei with IC50 of 7 μM.",179.3,"13392-28-4",33,184.05,33,184.05,"http://selleckchem.com/products/rimantadine-flumadine.html","C12H21N","free base","N/A","CC(N)[C]12C[CH]3[CH2]C([CH2][CH](C3)C1)C2",2.204,0,1,1]
["S1965","Primidone","a5","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.3;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","040586,040626,040667,040717,040862,040866,083551,084903,085052","Neurological Disease","Sodium Channel","Transmembrane Transporters","Primidone (NCI-C56360) is an anticonvulsant of the pyrimidinedione class.",218.25,"125-33-7",44,201.6,"<1",0,"http://selleckchem.com/products/Primidone(Mysoline).html","C12H14N2O2","free base","NCI-C56360","CCC1(C(=O)NCNC1=O)C2=CC=CC=C2",0.931,2,2,2]
["S1969","Nefiracetam","b5","L1300-06","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","GABA Receptor","Neuronal Signaling","Nefiracetam (DZL 221) is a GABAergic, cholinergic, and monoaminergic neuronal system enhancer for Ro 5-4864-induced convulsions. Phase 2.",246.3,"77191-36-7",49,198.94,5,20.3,"http://selleckchem.com/products/Nefiracetam(Translon).html","C14H18N2O2","free base","DZL 221","CC1=CC=CC(=C1NC(=O)CN2CCCC2=O)C",1.443,2,1,3]
["S1971","Nicorandil","c5","L1300-06","in 10mM DMSO","DMF,CFDA,PMDA,HMA","BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia",null,"Angiology/Cardiovascular Disease","Potassium Channel","Transmembrane Transporters","Nicorandil (SG-75) is a potassium channel activator, and stimulates guanylate cyclase to increase formation of cyclic GMP (cGMP).",211.17,"65141-46-0",42,198.89,17,80.5,"http://selleckchem.com/products/Nicorandil(Ikorel).html","C8H9N3O4","free base","SG-75","[O-][N+](=O)OCCNC(=O)C1=CC=CN=C1",1.758,3,1,5]
["S1972","Tamoxifen (ICI 46474) Citrate","d5","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","070929,074504,074539,074732,075740,075797,076027,076179,076398,090878,206694","Cancer","Apoptosis related,Autophagy,Estrogen/progestogen Receptor,HSP (HSP90)","Endocrinology & Hormones","Tamoxifen Citrate (Istubal,ICI 46474 Citrate) is a selective estrogen receptor modulator (SERM). Tamoxifen Citrate is also a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen induces apoptosis and autophagy.",563.64,"54965-24-1",100,177.42,"<1",0,"http://selleckchem.com/products/Tamoxifen-Citrate(Nolvadex).html","C26H29NO.C6H8O7","Citrate","Istubal,ICI 46474 Citrate","CC/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(OCCN(C)C)C=C3.OC(=O)CC(O)(CC(O)=O)C(O)=O",1.966,4,0,13]
["S1973","Cyclocytidine HCl","e5","L1300-06","in 10mM DMSO","CFDA",null,null,"Cancer","DNA/RNA Synthesis","DNA Damage/DNA Repair","Cyclocytidine (NSC 145668) is the prodrug of cytarabine, which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia.",261.66,"10212-25-6",10,38.22,44,168.16,"http://selleckchem.com/products/cyclocytidine-hcl.html","C9H12ClN3O4","Hydrochloride","NSC 145668 HCl","Cl.OCC1OC2C(OC3=NC(=N)C=CN23)C1O",-1.395,3,2,1]
["S1974","Meglumine","f5","L1300-06","in 10mM DMSO",null,"USP42-NF37;EP9.8;KP Ⅹ;JP17;Ph.Int_6th;Martindale:The Extra Pharmacopoeia",null,"Diagnosis","Others","Others","Meglumine(Meglumin,Methylglucamine) is an amino sugar derived from sorbitol for THP-1 cells with IC50 of 22 μg/mL.",195.21,"6284-40-8",39,199.78,39,199.78,"http://selleckchem.com/products/meglumine.html","C7H17NO5","free base","Meglumin,Methylglucamine","CNCC(O)C(O)C(O)C(O)CO",-2.798,0,6,6]
["S1975","Aripiprazole","g5","L1300-06","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","078583,078607,078608,078612,078613,078614,078708,090165,090472,091279,201519,202101,202102,202547,202683,203906,203908,204094,204111,204171,204838,205064,205363,206174,206240,206251,206383,207105,207240,208260,208438,210479","Psychotic disorders","5-HT Receptor","Neuronal Signaling","Aripiprazole (OPC-14597) is a novel atypical antipsychotic drug that is reported to be a high-affinity 5-HT receptor partial agonist.",448.39,"129722-12-9",90,200.72,"<1",0,"http://selleckchem.com/products/aripiprazole-abilify.html","C23H27Cl2N3O2","free base","OPC-14597","ClC1=CC=CC(=C1Cl)N2CCN(CCCCOC3=CC=C4CCC(=O)NC4=C3)CC2",4.998,2,1,7]
["S1978","Methscopolamine","h5","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37","040624,040642,080970,200602","Gastrointestinal Disease","AChR","Neuronal Signaling","Methscopolamine is a muscarinic acetylcholine receptor blocker.",398.29,"155-41-9",79,198.35,67,168.22,"http://selleckchem.com/products/Methscopolamine-bromide(Pamine).html","C18H24BrNO4","quaternary-N bromide salt","N/A","[Br-].C[N+]1(C)C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",-2.949,3,1,5]
["S1979","Amiodarone (NSC 85442) HCl","a6","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","021594,074739,074895,075188,075315,075389,075424,075761,075955,076018,076088,076108,076163,076217,076232,076299,076362,076394,077069,077161,077234,077610,077834,078578,079029,203884,203885,204550,204742","Cardiovascular Disease","Autophagy,Potassium Channel","Transmembrane Transporters","Amiodarone (NSC 85442,Amiodar,Amiodarone hydrochloride,Nexterone) HCl is a sodium/potassium-ATPase inhibitor and an autophagy activator, used to treat various types of cardiac dysrhythmias.",681.77,"19774-82-4",23,33.74,"<1",0,"http://selleckchem.com/products/amiodarone-hcl.html","C25H29I2NO3.HCl","Hydrochloride","Amiodar,Amiodarone hydrochloride,Nexterone","Cl.CCCCC1=C(C(=O)C2=CC(=C(OCCN(CC)CC)C(=C2)I)I)C3=C(O1)C=CC=C3",7.62,3,0,11]
["S1983","Adenine HCl","b6","L1300-06","in 10mM DMSO","DMF,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP16;Martindale:The Extra Pharmacopoeia",null,"Others","DNA/RNA Synthesis","DNA Damage/DNA Repair","Adenine HCl(6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.",171.59,"2922-28-3",8,46.62,4,23.31,"http://selleckchem.com/products/adenine-hydrochloride.html","C5H5N5.HCl","Hydrochloride","6-Aminopurine hydrochloride","Cl.NC1=NC=NC2=C1N=C[NH]2",-0.06,3,2,0]
["S1987","Mometasone furoate","c6","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.5;IP2010;Martindale:The Extra Pharmacopoeia","075919,076067,076171,076481,076499,076591,076624,076679,076788,077061,077180,077401,077447,077678,078541,078571,090506,091161,207899,207989","Immunology","Glucocorticoid Receptor","Endocrinology & Hormones","Mometasone Furoate (SCH-32088,mometasone 17-furoate) is a glucocorticoid receptor agonist, used topically to reduce inflammation of the skin or in the airways.",521.43,"83919-23-7",6,11.51,"<1",0,"http://selleckchem.com/products/mometasone-furoate.html","C27H30Cl2O6","Furoate","SCH-32088,mometasone 17-furoate","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(Cl)C(O)CC2(C)C1(OC(=O)C5=CC=CO5)C(=O)CCl",4.616,5,1,5]
["S1988","Propylthiouracil","d6","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","006188,006213,080015,080016,080154,080159,080172,080215,080285,080840,080932,083982,084075,084543,085201","Endocrinology","Peroxidases","Metabolism","Propylthiouracil (NSC 6498, NSC 70461) is a thyroperoxidase and 5'-deiodinase inhibitor, used to treat hyperthyroidism.",170.23,"51-52-5",34,199.73,"<1",0,"http://selleckchem.com/products/Propylthiouracil.html","C7H10N2OS","free base","NSC 6498, NSC 70461","CCCC1=CC(=O)NC(=S)N1",1.575,1,2,2]
["S1990","Capsaicin(Vanilloid)","e6","L1300-06","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","022395","Neurological Disease","TRP Channel","Transmembrane Transporters","Capsaicin (Qutenza, Vanilloid) is an active component of chili peppers, which are plants belonging to the genus Capsicum.Capsaici is a TRPV1 agonist with an EC50 of 0.29 μM in HEK293 cells.",305.41,"404-86-4",61,199.73,"<1",0,"http://selleckchem.com/products/capsaicin.html","C18H27NO3",0,"Qutenza, Vanilloid","COC1=C(O)C=CC(=C1)CNC(=O)CCCC\\C=C\\C(C)C",3.91,2,2,9]
["S1992","Fluticasone propionate","f6","L1300-06","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","076300,076451,076504,076633,076668,076793,076865,077055,077145,077168,077538,077570,078492,090759,091553,207957,208024,208150","Immunology","Glucocorticoid Receptor","Endocrinology & Hormones","Fluticasone Propionate (CCI-187881) is a synthetic glucocorticoid, used to treat non-allergic and allergic rhinitis.",500.57,"80474-14-2",100,199.77,"<1",0,"http://selleckchem.com/products/fluticasone-propionate-Flonase-Veramyst.html","C25H31F3O5S","free base","CCI-187881","CCC(=O)OC1(C(C)CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)SCF",4.086,4,1,6]
["S1994","Lacidipine","g6","L1300-06","in 10mM DMSO","DMF,CFDA,HMA","BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Lacidipine (GX-1048, GR-43659X, SN-305) is a L-type calcium channel blocker, used for treating high blood pressure.",455.54,"103890-78-4",91,199.76,"<1",0,"http://selleckchem.com/products/lacidipine-lacipil-motens.html","C26H33NO6","free base","GX-1048, GR-43659X, SN-305","CCOC(=O)C1=C(C)NC(=C(C1C2=C(C=CC=C2)\\C=C\\C(=O)OC(C)(C)C)C(=O)OCC)C",3.824,6,1,11]
["S2001","Elvitegravir (JTK-303)","h6","L1300-06","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","203093,207561,203100","Infection","Integrase","Microbiology","Elvitegravir (GS-9137,JTK-303,D06677) is an HIV integrase inhibitor for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM in cell-free assays, respectively.",447.88,"697761-98-1",89,198.71,"<1",0,"http://selleckchem.com/products/Elvitegravir.html","C23H23ClFNO5","free base","GS-9137,JTK-303,D06677","COC1=CC2=C(C=C1CC3=C(F)C(=CC=C3)Cl)C(=O)C(=CN2C(CO)C(C)C)C(O)=O",4.665,3,1,7]
["S2003","Maraviroc (UK-427857)","a7","L1300-06","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","203347,203382","Infection","CCR,HIV","Microbiology","Maraviroc (Celsentri,UK-427857) is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM in cell-free assays, respectively. Maraviroc is used in the treatment of HIV infection.",513.67,"376348-65-1",100,194.68,"<1",0,"http://selleckchem.com/products/Maraviroc.html","C29H41F2N5O","free base","Celsentri,UK-427857","CC(C)C1=NN=C(C)[N]1C2CC3CCC(C2)N3CCC(NC(=O)C4CCC(F)(F)CC4)C5=CC=CC=C5",3.921,3,1,8]
["S2005","Raltegravir (MK-0518)","b7","L1300-06","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","USP42-NF37;EP9.4;BP2019;Martindale:The Extra Pharmacopoeia","203540","Infection","Integrase","Microbiology","Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM in cell-free assays, respectively. It shows greater than 1000-fold selectivity for HIV-1 IN over several related Mg2+-dependent enzyme such as HCV polymerase, HIV reverse transcriptase, HIV RNaseH and human α-, β-, γ-polymerases.",444.42,"518048-05-0",88,198.01,"<1",0,"http://selleckchem.com/products/Raltegravir-(MK-0518).html","C20H21FN6O5","free base","MK-0518","CN1C(=O)C(=C(N=C1C(C)(C)NC(=O)C2=NN=C(C)O2)C(=O)NCC3=CC=C(F)C=C3)O",-0.291,7,3,6]
["S2006","Pyrimethamine","c7","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;EP9.7;BP2019;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","008578,018557","Infection/Parasitology/Respiratory Disease","DHFR","Metabolism","Pyrimethamine(RP 4753) is a dihydrofolate reductase (DHFR) inhibitor, used as an antimalarial drug.",248.71,"58-14-0",10,40.21,"<1",0,"http://selleckchem.com/products/Pyrimethamine.html","C12H13ClN4","free base","RP 4753","CCC1=NC(=NC(=C1C2=CC=C(Cl)C=C2)N)N",2.75,2,2,2]
["S2007","Sulindac","d7","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","071795,071891,072050,072051,072710,072711,072712,072713,072972,072973,073038,073039,073261,073262","Inflammation","COX","Neuronal Signaling","Sulindac(MK-231) is a non-steroidal COX inhibitor, which potently inhibits prostaglandin synthesis, used in the treatment of acute or chronic inflammatory conditions.",356.41,"38194-50-2",71,199.21,"<1",0,"http://selleckchem.com/products/Sulindac(Clinoril).html","C20H17FO3S","free base","MK-231","CC1=C(CC(O)=O)C2=C(C=CC(=C2)F)\\C1=C/C3=CC=C(C=C3)[S](C)=O",3.639,2,0,4]
["S2011","Pramipexole 2HCl Monohydrate","e7","L1300-06","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","077724,077854,078551,078894,078920,090151,090190,090241,090764,090781,090865,091254,091450,091683,201963,202164,202206,202353,202633,202702,202891,203354,203615,203855,204518,206156,207011,211088","Neurological Disease","Dopamine Receptor","Neuronal Signaling","Pramipexole 2HCl Monohydrate is a novel non-ergoline dopamine (DA) agonist, used to treat Parkinson's disease.",302.26,"191217-81-9",41,135.64,60,198.5,"http://selleckchem.com/products/Pramipexole-dihydrochloride-monohydrate.html","C10H17N3S.2HCl.H2O","Dihydrochloride monohydrate","N/A","O.Cl.Cl.CCCNC1CCC2=C(C1)SC(=N2)N",1.94,1,2,3]
["S2015","Suplatast Tosylate","f7","L1300-06","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia",null,"Immunology","Interleukins","Immunology & Inflammation","Suplatast Tosylate (IPD-1151T, Suplatast Tosilate) is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM.",499.64,"94055-76-2",100,200.14,100,200.14,"http://selleckchem.com/products/suplatast-tosilate.html","C23H33NO7S2","Tosylate","IPD-1151T, Suplatast Tosilate","CCOCC(O)COC1=CC=C(NC(=O)CC[S+](C)C)C=C1.CC2=CC=C(C=C2)[S]([O-])(=O)=O",0.877,3,2,11]
["S2016","Mirtazapine","g7","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","076119,076122,076176,076189,076219,076241,076244,076270,076307,076308,076312,076336,076541,076689,076901,076921,077376,077666,077959,205798","Psychotic disorders","5-HT Receptor","Neuronal Signaling","Mirtazapine (Org3770,6-Azamianserin) is an adrenergic and seroton receptor antagonist, used to treat depression.",265.35,"85650-52-8",53,199.74,"<1",0,"http://selleckchem.com/products/mirtazapine-remeron-avanza.html","C17H19N3","free base","Org3770,6-Azamianserin","CN1CCN2C(C1)C3=C(CC4=C2N=CC=C4)C=CC=C3",3.094,1,0,0]
["S2017","Benidipine HCl","h7","L1300-06","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Benidipine HCl (KW-3049,(±)- Benidipine) is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker.",542.02,"91599-74-5",8,14.76,"<1",0,"http://selleckchem.com/products/benidipine-hydrochloride.html","C28H31N3O6.HCl","Hydrochloride","KW-3049,(±)- Benidipine","Cl.COC(=O)C1=C(C)NC(=C(C1C2=CC(=CC=C2)[N+]([O-])=O)C(=O)OC3CCCN(C3)CC4=CC=CC=C4)C",4.36,4,1,9]
["S2020","Formoterol Hemifumarate","a8","L1300-06","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","091141","Inflammation","Adrenergic Receptor","Neuronal Signaling","Formoterol Hemifumarate (Eformoterol, CGP 25827A, NSC 299587, YM 08316,Formoterol fumarate) is a potent, selective and long-acting β2-adrenoceptor agonist used in the management of asthma and chronic obstructive pulmonary disease(COPD).",402.4,"43229-80-7",80,198.81,"<1",0,"http://selleckchem.com/products/formoterol-hemifumarate.html","C19H24N2O4.1/2C4H4O4","Hemifumarate","Eformoterol, CGP 25827A, NSC 299587, YM 08316,Formoterol fumarate","COC1=CC=C(CC(C)NCC(O)C2=CC=C(O)C(=C2)NC=O)C=C1.COC3=CC=C(CC(C)NCC(O)C4=CC=C(O)C(=C4)NC=O)C=C3.OC(=O)\\C=C\\C(O)=O",-1.526,6,8,18]
["S2021","Chlormezanone","b8","L1300-06","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia","011467","Neurological Disease","Others","Others","Chlormezanone，a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.",273.74,"80-77-3",55,200.92,"<1",0,"http://selleckchem.com/products/Chlormezanone(Trancopal).html","C11H12ClNO3S","free base","N/A","CN1C(C2=CC=C(Cl)C=C2)[S](=O)(=O)CCC1=O",1.559,3,0,1]
["S2024","Ketotifen Fumarate","c8","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","077354,077958","Immunology/Inflammation","Histamine Receptor","Neuronal Signaling","Ketotifen Fumarate(HC 20511 fumarate) is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer.",425.5,"34580-14-8",8,18.8,"<1",0,"http://selleckchem.com/products/ketotifen-fumarate-zaditor.html","C19H19NOS.C4H4O4","Fumarate","HC 20511 fumarate","CN1CCC(CC1)=C2C3=C(CC(=O)C4=C2C=CS4)C=CC=C3.OC(=O)\\C=C\\C(O)=O",0.772,3,0,2]
["S2025","Urapidil HCl","d8","L1300-06","in 10mM DMSO","DMF,CFDA,PMDA,HMA","JP17;Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","5-HT Receptor","Neuronal Signaling","Urapidil HCl is a hydrochloride salt form of urapidil which is α1-adrenoceptor antagonist and 5-HT1A receptor agonist with pIC50 of 6.13 and 6.4 respectively.",423.94,"64887-14-5",24,56.61,85,200.5,"http://selleckchem.com/products/urapidil-hydrochloride.html","C20H29N5O3.HCl","Hydrochloride","N/A","Cl.COC1=CC=CC=C1N2CCN(CCCNC3=CC(=O)N(C)C(=O)N3C)CC2",1.808,3,1,7]
["S2028","Diclazuril","e8","L1300-06","in 10mM DMSO","DMF","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Infection","Parasite","Microbiology","Diclazuril(R-64433) is an anti-coccidial drug.",407.64,"101831-37-2",16,39.25,"<1",0,"http://selleckchem.com/products/diclazuril.html","C17H9Cl3N4O2","free base","R-64433","ClC1=CC=C(C=C1)C(C#N)C2=C(Cl)C=C(C=C2Cl)N3N=CC(=O)NC3=O",4.191,3,1,3]
["S2029","Uridine","f8","L1300-06","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;EP9.2;BP2017;IP2010;Martindale:The Extra Pharmacopoeia","208169","Cardiovascular Disease","DNA/RNA Synthesis","DNA Damage/DNA Repair","Uridine (NSC 20256,β-Uridine, Uridin) is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond.",244.2,"58-96-8",49,200.66,49,200.66,"http://selleckchem.com/products/uridine.html","C9H12N2O6","free base","NSC 20256,β-Uridine, Uridin","OCC1OC(C(O)C1O)N2C=CC(=O)NC2=O",-2.451,3,4,2]
["S2030","Flunarizine 2HCl","g8","L1300-06","in 10mM DMSO","DMF,CFDA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Angiology/Cardiovascular Disease/Neurological Disease","Calcium Channel","Transmembrane Transporters","Flunarizine 2HCl (KW-3149, R14950) is a dihydrochloride salt form which is a calcium channel blocker with a Ki of 68 nM.",477.42,"30484-77-6",5,10.47,"<1",0,"http://selleckchem.com/products/flunarizine-dihydrochloride.html","C26H26F2N2.2HCl","2HCl","KW-3149, R14950","Cl.Cl.FC1=CC=C(C=C1)C(N2CCN(CC2)C\\C=C\\C3=CC=CC=C3)C4=CC=C(F)C=C4",6.699,0,0,6]
["S2031","Fenticonazole Nitrate","h8","L1300-06","in 10mM DMSO","DMF,HMA","BP2019;EP9.2;KP Ⅹ;Martindale:The Extra Pharmacopoeia",null,"Infection","Fungal","Microbiology","Fenticonazole Nitrate(Lomexin,REC 15-1476,Falvin) is an azole antifungal agent.",518.41,"73151-29-8",104,200.61,"<1",0,"http://selleckchem.com/products/fenticonazole-nitrate.html","C24H20Cl2N2OS.HNO3","Nitrate","Lomexin,REC 15-1476,Falvin","O[N+]([O-])=O.ClC1=CC=C(C(C[N]2C=CN=C2)OCC3=CC=C(SC4=CC=CC=C4)C=C3)C(=C1)Cl",5.176,2,0,8]
["S2032","Rebamipide","a9","L1300-06","in 10mM DMSO","DMF,CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Inflammation","CCK receptor","GPCR & G Protein","Rebamipide (OPC-12759,Proamipide) is a cholecystokinin type 1 (CCK1) receptor inhibitor for inhibiting [125I]BH-CCK-8S with IC50 of 37.7 μM.",370.79,"90098-04-7",74,199.57,"<1",0,"http://selleckchem.com/products/rebamipide.html","C19H15ClN2O4","free base","OPC-12759,Proamipide","OC(=O)C(CC1=CC(=O)NC2=C1C=CC=C2)NC(=O)C3=CC=C(Cl)C=C3",2.606,3,2,5]
["S2036","Aspartame","b9","L1300-06","in 10mM DMSO","NDC","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Aspartame (SC-18862,Nutrasweet) is an artificial, non-saccharide sweetener used as a sugar substitute in some foods and beverages.",294.3,"22839-47-0",33,112.13,4,13.59,"http://selleckchem.com/products/aspartame.html","C14H18N2O5","free base","SC-18862,Nutrasweet","COC(=O)C(CC1=CC=CC=C1)NC(=O)C(N)CC(O)=O",-2.455,4,2,8]
["S2037","Candesartan Cilexetil","c9","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","078702,091390,202079,203813,209119,210302","Cardiovascular Disease","Angiotensin Receptor","GPCR & G Protein","Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist with IC50 of 0.26 nM, used in the treatment of hypertension.",610.66,"145040-37-5",122,199.78,"<1",0,"http://selleckchem.com/products/Candesartan-cilexetil-Atacand.html","C33H34N6O6","free base","TCV-116","CCOC1=NC2=C([N]1CC3=CC=C(C=C3)C4=C(C=CC=C4)C5=NN=N[NH]5)C(=CC=C2)C(=O)OC(C)OC(=O)OC6CCCCC6",6.913,10,1,13]
["S2038","Phentolamine Mesylate","d9","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","SP42-NF37;IP2010","040235,207686","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Phentolamine Mesylate(Phentolamine methanesulfonate) is a reversible and nonselective alpha-adrenergic receptor antagonist, used for the prevention or control of hypertensive episodes.",377.46,"65-28-1",76,201.35,76,201.35,"http://selleckchem.com/products/phentolamine-mesilate.html","C17H19N3O.CH4O3S","Mesylate","Phentolamine methanesulfonate","CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.C[S](O)(=O)=O",2.555,1,2,4]
["S2040","Nimesulide","e9","L1300-06","in 10mM DMSO","DMF,CFDA,HMA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Inflammation","COX","Neuronal Signaling","Nimesulide is a relatively COX-2 selective inhibitor with IC50 of 26 μM.",308.31,"51803-78-2",62,201.1,"<1",0,"http://selleckchem.com/products/Nimesulide.html","C13H12N2O5S","free base","N/A","C[S](=O)(=O)NC1=C(OC2=CC=CC=C2)C=C(C=C1)[N+]([O-])=O",2.195,3,1,5]
["S2041","Dyclonine HCl","f9","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","009925,200480","Neurological Disease","Sodium Channel","Transmembrane Transporters","Dyclonine HCl(Dyclocaine HCl) is a hydrochloride salt form of dyclonine which is an oral anaesthetic, reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation.",325.87,"536-43-6",15,46.03,6,18.41,"http://selleckchem.com/products/dyclonine-hydrochloride.html","C18H27NO2.HCl","Hydrochloride","Dyclocaine HCl","Cl.CCCCOC1=CC=C(C=C1)C(=O)CCN2CCCCC2",4.435,2,0,8]
["S2042","Cyproterone Acetate","g9","L1300-06","in 10mM DMSO","DMF,CFDA,HMA","BP2019;EP9.2;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia",null,"Cancer","Androgen Receptor","Endocrinology & Hormones","Cyproterone acetate is an androgen receptor (AR) antagonist with IC50 of 7.1 nM, as well as a weak progesterone receptor agonist with weak pro-gestational and glucocorticoid activity.",416.94,"427-51-0",83,199.07,"<1",0,"http://selleckchem.com/products/cyproterone-acetate.html","C24H29ClO4","free base","N/A","CC(=O)OC1(CCC2C3C=C(Cl)C4=CC(=O)C5CC5C4(C)C3CCC12C)C(C)=O",3.314,4,0,3]
["S2043","Memantine HCl","h9","L1300-06","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","079225,090041,090043,090044,090048,090051,090052,090058,090073,090244,090961,091585,200022,200155,200891,202350,202790,202840,203175,203293,204033,205446,205784,205825,205905,206028,206032,206135,206310,206528,206855,207236,209527,209955","Neurological Disease","NMDAR","Neuronal Signaling","Memantine HCl is an antagonist of NMDAR. It is also a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6 with IC50 of 1.12 μM and 242.4 μM, Ki of 0.51 μM and 84.4 μM, respectively.",215.76,"41100-52-1",43,199.3,30,139.04,"http://selleckchem.com/products/memantine-hydrochloride-namenda.html","C12H21N.HCl","Hydrochloride","N/A","Cl.CC12C[CH]3CC(C)([CH2]1)C[C](N)(C3)C2",2.289,0,1,0]
["S2044","Cyproheptadine HCl","a10","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","040537,040644,040668,085245,086165,086580,086678,086737,086808,086833,087001,087056,087129,087284,087405,087566,087685,087839,088205,088212,088232,088798,089021,089057,089199,091295,203191,204823,205087,206553,206676,207555,207783,208938,209108,209172,212423","Immunology","Histamine Receptor","Neuronal Signaling","Cyproheptadine HCl(Periactin) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist.",323.86,"969-33-5",65,200.7,"<1",0,"http://selleckchem.com/products/cyproheptadine-hydrochloride-periactin.html","C21H21N.HCl","Hydrochloride","Periactin","Cl.CN1CCC(CC1)=C2C3=C(C=CC=C3)C=CC4=C2C=CC=C4",4.744,0,0,0]
["S2045","Doxifluridine","b10","L1300-06","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Cancer","Phosphorylase","Metabolism","Doxifluridine (5'-DFUR, AMC 0101) is an oral prodrug that is converted to the cytotoxic agent 5-fluorouracil (5-FU).",246.19,"3094-09-5",49,199.03,49,199.03,"http://selleckchem.com/products/doxifluridine.html","C9H11FN2O5","free base","5'-DFUR, AMC 0101","CC1OC(C(O)C1O)N2C=C(F)C(=O)NC2=O",-1.653,3,3,1]
["S2046","Pioglitazone HCl","c10","L1300-06","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","076798,076801,077210,078383,078472,078670,091298,200044,200268,202456,202467,204133,206738,207806","Endocrinology/Metabolic Disease","Ferroptosis,P450 (e.g. CYP17),PPAR","Metabolism","Pioglitazone HCl (AD-4833, U-72107E) is an inhibitor of cytochrome P450 (CYP)2C8 and CYP3A4 enzymes. Pioglitazone HCl inhibits CYP2C8, CYP3A4 and CYP2C9 with Ki of 1.7 μM, 11.8 μM and 32.1 μM, respectively. Pioglitazone HCl is also a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist with EC50 of 0.93 μM and 0.99 μM for human PPARγ and mouse PPARγ, respectively. Pioglitazone HCl inhibits mitochondrial iron uptake, lipid peroxidation, and subsequent ferroptosis.",392.9,"112529-15-4",79,201.07,"<1",0,"http://selleckchem.com/products/pioglitazone-hydrochloride-actos.html","C19H20N2O3S.HCl","Hydrochloride","AD-4833, U-72107E","Cl.CCC1=CC=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)N=C1",4.289,4,1,7]
["S2051","Captopril","d10","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","074322,074363,074386,074418,074423,074433,074434,074451,074462,074472,074477,074481,074483,074493,074505,074519,074532,074576,074590,074640,074677,074737,074748","Cardiovascular Disease","ACE,RAAS","Endocrinology & Hormones","Captopril (SQ 14225,Capoten) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.",217.29,"62571-86-2",43,197.89,2,9.2,"http://selleckchem.com/products/captopril-capoten.html","C9H15NO3S","free base","SQ 14225,Capoten","CC(CS)C(=O)N1CCCC1C(O)=O",0.667,2,0,3]
["S2052","Oxytetracycline Dihydrate","e10","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,PMDA","EP9.2;JP17;BP2017 ;Ph.Int_5th;Martindale:The Extra Pharmacopoeia","060634,060760,060770,060869","Infection","Antibiotics,Bacterial","Microbiology","Oxytetracycline Dihydrate is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.",496.46,"6153-64-6",5,10.07,"<1",0,"http://selleckchem.com/products/oxytetracycline-dihydrate.html","C22H24N2O9.2H2O","Dihydrate","N/A","O.O.CN(C)C1C2C(O)C3C(=C(O)C2(O)C(=O)C(=C1O)C(N)=O)C(=O)C4=C(O)C=CC=C4C3(C)O",-2.309,3,5,2]
["S2053","Cytidine","f10","L1300-06","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia",null,"Cancer","Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA.",243.22,"65-46-3",49,201.46,49,201.46,"http://selleckchem.com/products/cytidine.html","C9H13N3O5","free base","N/A","NC1=NC(=O)N(C=C1)C2OC(CO)C(O)C2O",-2.396,3,4,2]
["S2054","Orphenadrine Citrate","g10","L1300-06","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","040249,040284,040327,040368,040463,040484,084303,084779,085046,087062,088067,090585,091158","Neurological Disease","AChR","Neuronal Signaling","Orphenadrine Citrate is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.",461.5,"4682-36-4",92,199.35,"<1",0,"http://selleckchem.com/products/orphenadrine-citrate-norflex.html","C18H23NO.C6H8O7","Citrate","N/A","CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2C.OC(=O)CC(O)(CC(O)=O)C(O)=O",-0.483,4,0,11]
["S2055","Gimeracil","h10","L1300-06","in 10mM DMSO","EMA,CFDA",null,null,"Cancer/Gastroenterology/Respiratory Disease","Dehydrogenase","Metabolism","Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase, which inhibits the early step in homologous recombination for double strand breaks repair.",145.54,"103766-25-2",29,199.26,"<1",0,"http://selleckchem.com/products/gimeracil.html","C5H4ClNO2","free base","N/A","OC1=CC(=O)NC=C1Cl",-0.493,1,2,0]
["S2057","Cyclophosphamide (NSC-26271) Monohydrate","a11","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","040032,040745,088371,088372,088373,088374,203856,204555,207014,209872,210046,211608","Cancer/Hematology","DNA alkylator","DNA Damage/DNA Repair","Cyclophosphamide (NSC-26271, Cytoxan) Monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA, shown to crosslink DNA, causing strand breakage and inducing mutations.",279.1,"6055-19-2",55,197.06,7,25.08,"http://selleckchem.com/products/cyclophosphamide-monohydrate.html","C7H15Cl2N2O2P.H2O","Monohydrate","Cytoxan Monohydrate","O.ClCCN(CCCl)[P]1(=O)NCCCO1",-0.063,2,1,5]
["S2058","Tolnaftate","b11","L1300-06","in 10mM DMSO","DMF,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia",null,"Infection","Fungal","Microbiology","Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.",307.41,"2398-96-1",62,201.69,"<1",0,"http://selleckchem.com/products/tolnaftate.html","C19H17NOS","free base","N/A","CN(C(=S)OC1=CC=C2C=CC=CC2=C1)C3=CC(=CC=C3)C",6.289,1,0,4]
["S2059","Terazosin HCl Dihydrate","c11","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","074315,074446,074530,074657,074823,075140,075317,075384,075498,075614,075667,076021","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Terazosin HCl is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH).",459.92,"70024-40-7",26,56.53,"<1",0,"http://selleckchem.com/products/terazosin-hydrochloride-hytrin.html","C19H25N5O4.HCl.2H2O","HCl & Dihydrate","N/A","O.O.Cl.COC1=CC2=C(C=C1OC)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N",1.348,6,1,4]
["S2060","Bromhexine HCl","d11","L1300-06","in 10mM DMSO","CFDA,PMDA,HMA","BP2019;EP9.2;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia",null,"Respiratory Disease","Others","Others","Bromhexine HCl is a medication prescribed for coughs which works by dissolving hard phlegm.",412.59,"611-75-6",6,14.54,"<1",0,"http://selleckchem.com/products/bromhexine-hydrochloride.html","C14H20Br2N2.HCl","HCl","N/A","Cl.CN(CC1=CC(=CC(=C1N)Br)Br)C2CCCCC2",4.894,0,1,3]
["S2061","Lovastatin (MK-803)","e11","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Martindale:The Extra Pharmacopoeia","075300,075451,075551,075636,075828,075935,075991,077520,077748,078296","Cardiovascular Disease","Autophagy,HMG-CoA Reductase","Metabolism","Lovastatin (MK-803, Mevinolin,Mevacor) is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM in a cell-free assay, used for lowering cholesterol (hypolipidemic agent). Lovastatin triggers autophagy.",404.54,"75330-75-5",8,19.78,"<1",0,"http://selleckchem.com/products/lovastatin-mevacor.html","C24H36O5","free base","Mevinolin,Mevacor","CCC(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C12",4.218,4,1,7]
["S2062","Tiopronin","f11","L1300-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","019569","Metabolic Disease","ROS","Immunology & Inflammation","Tiopronin is an antioxidant agent, used for the treatment of cystinuria by controlling the rate of cystine precipitation and excretion.",163.19,"1953-02-2",32,196.09,32,196.09,"http://selleckchem.com/products/tiopronin-thiola.html","C5H9NO3S","free base","N/A","CC(S)C(=O)NCC(O)=O",-0.362,2,1,3]
["S2064","Balofloxacin","g11","L1300-06","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Infection","Topoisomerase","DNA Damage/DNA Repair","Balofloxacin (Q-35,Q-roxin) is a quinolone antibiotic, inhibiting the synthesis of bacterial DNA by interference with the enqyme DNA gyrase.",389.42,"127294-70-6",5,12.84,"<1",0,"http://selleckchem.com/products/balofloxacin.html","C20H24FN3O4","free base","Q-35,Q-roxin","CNC1CCCN(C1)C2=C(OC)C3=C(C=C2F)C(=O)C(=CN3C4CC4)C(O)=O",-0.615,3,1,5]
["S2065","Lafutidine","h11","L1300-06","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Inflammation/Gastrointestinal Disease/Respiratory Disease","Histamine Receptor","Neuronal Signaling","Lafutidine (FRG-8813), a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.",431.55,"118288-08-7",86,199.28,"<1",0,"http://selleckchem.com/products/lafutidine.html","C22H29N3O4S","free base","FRG-8813","O=C(C[S](=O)CC1=CC=CO1)NC\\C=C/COC2=CC(=CC=N2)CN3CCCCC3",1.987,5,1,11]
["S2066","Moxonidine","a2","L1300-07","in 10mM DMSO","DMF,CFDA,HMA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Imidazoline Receptor","GPCR & G Protein","Moxonidine (BDF5895) is a selective agonist at the imidazoline receptor subtype 1, used as antihypertensive agent.",241.68,"75438-57-2",24,99.3,"<1",0,"http://selleckchem.com/products/moxonidine.html","C9H12ClN5O","free base","BDF5895","COC1=NC(=NC(=C1NC2=NCCN2)Cl)C",0.598,4,2,3]
["S2067","Ozagrel HCl","b2","L1300-07","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Angiology/Neurological Disease","P450 (e.g. CYP17),Prostaglandin Receptor","Metabolism","Ozagrel HCl (OKY-046) is a selective <n>thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.",264.71,"78712-43-3",52,196.44,52,196.44,"http://selleckchem.com/products/ozagrel-hydrochloride.html","C13H12N2O2.HCl","HCl","OKY-046 HCl","Cl.OC(=O)/C=C/C1=CC=C(C[N]2C=CN=C2)C=C1",1.986,2,0,4]
["S2069","Argatroban (MCI-9038)","c2","L1300-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;JP17;Martindale:The Extra Pharmacopoeia","020883,022359,079238,091665,201811,202626,203049,204120,206698,212035","Hematology","Thrombin","Proteases","Argatroban (MCI-9038) is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant.",508.63,"74863-84-6",9,17.69,"<1",0,"http://selleckchem.com/products/argatroban.html","C23H36N6O5S","free base","MCI-9038","CC1CCN(C(C1)C(O)=O)C(=O)C(CCCNC(N)=N)N[S](=O)(=O)C2=CC=CC3=C2NCC(C)C3",1.266,4,4,10]
["S2071","Prulifloxacin (NM441)","d2","L1300-07","in 10mM DMSO","DMF,PMDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Infection","COVID-19","Microbiology","Prulifloxacin (NM441, AF 3013), the prodrug of ulifloxacin, is a broad-spectrum oral fluoroquinolone antibacterial agent.",461.46,"123447-62-1",11,23.84,"<1",0,"http://www.selleckchem.com/products/prulifloxacin-pruvel.html","C21H20FN3O6S","Free Base","AF 3013","CC1SC2=C(C(O)=O)C(=O)C3=CC(=C(C=C3N12)N4CCN(CC4)CC5=C(C)OC(=O)O5)F",0.031,5,0,4]
["S2072","Seratrodast(AA-2414)","e2","L1300-07","in 10mM DMSO","CFDA,PMDA","Martindale the Extra Pharmacopoei",null,"Immunology","Prostaglandin Receptor","Metabolism","Seratrodast (AA-2414, ABT-001) is a potent and selective thromboxane A2 receptor (TP) antagonist which is used primarily in the treatment of asthma and used as anti-inflammatory agent.",354.44,"112665-43-7",71,200.32,"<1",0,"http://www.selleck.cn/products/seratrodast.html","C22H26O4","Free Base","ABT-001","CC1=C(C)C(=O)C(=C(C)C1=O)C(CCCCCC(O)=O)C2=CC=CC=C2",5.216,3,0,8]
["S2075","Rosiglitazone (BRL-49653) HCl","f2","L1300-07","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","USP42-NF37;IP2010;Martindale:The Extra Pharmacopoeia","076748,078023","Endocrinology/Metabolic Disease","PPAR","Metabolism","Rosiglitazone HCl (BRL-49653) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.",393.89,"302543-62-0",79,200.56,"<1",0,"http://selleckchem.com/products/rosiglitazone-hydrochloride.html","C18H19N3O3S.HCl","HCl","BRL-49653 HCl","Cl.CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C3=CC=CC=N3",3.65,4,1,7]
["S2077","Atorvastatin Calcium","g2","L1300-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","076477,077575,078773,090548,091226,091624,091650,202357,204846,204991,205300,205519,206536,207687,209288,209912,211933","Cardiovascular Disease","Apoptosis related,Autophagy,HMG-CoA Reductase","Metabolism","Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. Atorvastatin Calcium induces apoptosis and autophagy.",1155.34,"134523-03-8",100,86.55,"<1",0,"http://selleckchem.com/products/atorvastatin-calcium-lipitor.html","2(C33H34FN2O5).Ca","Calcium","N/A","[Ca++].CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C([N]1CCC(O)CC(O)CC([O-])=O)C3=CC=C(F)C=C3)C4=CC=CC=C4.CC(C)C5=C(C(=O)NC6=CC=CC=C6)C(=C([N]5CCC(O)CC(O)CC([O-])=O)C7=CC=C(F)C=C7)C8=CC=CC=C8",8.163,2,6,24]
["S2078","Famotidine","h2","L1300-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","075062,075192,075193,075194,075302,075311,075312,075400,075404,075457,075488,075511,075512,075607,075610,075611,075639,075650,075651,075674,075684,075704,075705,075707,075709,075715,075718,075758,075786,075793,075799,075805,075870,075905,075942,076101,077146,077351,077352,077367,078641,078916,090283,090440,090837,091020,201695,201995,206530,206531","Gastrointestinal Disease","Histamine Receptor","Neuronal Signaling","Famotidine (MK208) is a histamine H2–receptor antagonist with IC50 of 0.6 mM, commonly used to treat heartburn, GERD, ulcers, and other digestive conditions.",337.45,"76824-35-6",67,198.55,"<1",0,"http://selleckchem.com/products/famotidine-pepcid.html","C8H15N7O2S3","free base","MK208","NC(=N)NC1=NC(=CS1)CSCCC(=N)N[S](N)(=O)=O",-1.328,3,4,9]
["S2079","Moexipril HCl","a3","L1300-07","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","076204,077536,078454,090416","Cardiovascular Disease","ACE,COVID-19,RAAS","Endocrinology & Hormones","Moexipril HCl (RS-10085) is a potent orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, used for the treatment of hypertension and congestive heart failure.",535.03,"82586-52-5",20,37.38,"<1",0,"http://selleckchem.com/products/moexipril-hydrochloride.html","C27H34N2O7.HCl","Hydrochloride","RS-10085","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC(=C(OC)C=C3CC2C(O)=O)OC",1.005,6,1,12]
["S2080","Clevidipine Butyrate","b3","L1300-07","in 10mM DMSO","DMF,HMA",null,null,"Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Clevidipine Butyrate(Cleviprex) is a dihydropyridine calcium channel blocker,  uses as an agent for the reduction of blood pressure.",456.32,"167221-71-8",91,199.42,"<1",0,"http://selleckchem.com/products/cleviprex-clevidipine.html","C21H23Cl2NO6","free base","Cleviprex","CCCC(=O)OCOC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2Cl)Cl)C(=O)OC)C",4.145,6,1,10]
["S2082","Adiphenine HCl","c3","L1300-07","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Neurological Disease","AChR","Neuronal Signaling","Adiphenine HCl(NSC 129224) is a nicotinic receptor inhibitor, used as an antispasmodic drug.",347.88,"50-42-0",30,86.24,70,201.22,"http://selleckchem.com/products/adiphenine-hcl.html","C20H25NO2.HCl","HCl","NSC 129224","Cl.CCN(CC)CCOC(=O)C(C1=CC=CC=C1)C2=CC=CC=C2",4.433,2,0,9]
["S2083","Procaterol HCl","d3","L1300-07","in 10mM DMSO","DMF,CFDA","KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia",null,"Immunology","Adrenergic Receptor","Neuronal Signaling","Procaterol HCl (OPC-2009) is a short-acting β2-adrenergic receptor agonist with Kp of 8 nM, used for the treatment of asthma",326.82,"62929-91-3",65,198.89,65,198.89,"http://www.selleckchem.com/products/procaterol-hcl.html","C16H22N2O3.HCl","hydrochloride","OPC-2009","Cl.CCC(NC(C)C)C(O)C1=CC=C(O)C2=C1C=CC(=O)N2",2.781,1,4,5]
["S2084","Duloxetine HCl","e3","L1300-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","090669,090694,090723,090728,090739,090745,090773,090774,090775,090776,090778,090780,090783,202045,202336,202949,203088,203197,204343,204815,206653,208706,210599,211310","Neurological Disease/Psychotic disorders","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Duloxetine HCl (LY-248686) is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).",333.88,"136434-34-9",67,200.67,"<1",0,"http://selleckchem.com/products/duloxetine-hcl-cymbalta.html","C18H19NOS.HCl","HCl","LY-248686 HCl","Cl.CNCCC(OC1=C2C=CC=CC2=CC=C1)C3=CC=CS3",4.228,1,1,6]
["S2085","Trimebutine","f3","L1300-07","in 10mM DMSO","DMF,CFDA,PMDA","EP9.3;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia",null,"Gastroenterology","Opioid Receptor","Neuronal Signaling","Trimebutine (Mebutin) is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain.",387.47,"39133-31-8",50,129.04,"<1",0,"http://selleckchem.com/products/trimebutine.html","C22H29NO5","free base","Mebutin","CCC(COC(=O)C1=CC(=C(OC)C(=C1)OC)OC)(N(C)C)C2=CC=CC=C2",4.115,5,0,10]
["S2086","Ivabradine HCl","g3","L1300-07","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","Martindale:The Extra Pharmacopoeia","206143,209964","Cardiovascular Disease/Endocrinology","Adrenergic Receptor","Neuronal Signaling","Ivabradine HCl (S 16257-2,S-18982 D6 hydrochloride), a new If inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent.",505.05,"148849-67-6",101,199.98,82,162.36,"http://selleckchem.com/products/ivabradine-hcl-procoralan.html","C27H36N2O5.HCl","HCl","S 16257-2,S-18982 D6 hydrochloride","Cl.COC1=CC2=C(CC(=O)N(CCCN(C)CC3CC4=CC(=C(OC)C=C34)OC)CC2)C=C1OC",3.753,5,0,10]
["S2087","Rivastigmine Tartrate","h3","L1300-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","077129,077130,077131,090879,091072,091689,203148,203844,204572,207797","Neurological Disease","AChR","Neuronal Signaling","Rivastigmine Tartrate (ENA 713) is a cholinesterase inhibitor with IC50 of 5.5 μM, and used as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease.",400.42,"129101-54-8",42,104.89,80,199.79,"http://selleckchem.com/products/rivastigmine-tartrate-exelon.html","C14H22N2O2.C4H6O6","Tartrate","ENA 713","CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C.OC(C(O)C(O)=O)C(O)=O",-2.099,4,2,8]
["S2090","Dexmedetomidine HCl","a4","L1300-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","091465,201072,202126,202585,202881,203773,203972,204023,204686,204843,205046,205272,205867,206628,206798,207551,208129,208129,208532,209065","Neurological Disease/Psychotic disorders","Adrenergic Receptor","Neuronal Signaling","Dexmedetomidine HCl((+)-Medetomidine Hydrochloride) is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.",236.74,"145108-58-3",48,202.75,"<1",0,"http://selleckchem.com/products/dexmedetomidine-hcl-precedex.html","C13H16N2.HCl","HCl","(+)-Medetomidine Hydrochloride","Cl.CC(C1=CN=C[NH]1)C2=CC=CC(=C2C)C",3.378,1,1,2]
["S2091","Betaxolol","b4","L1300-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","075386,075446,075541,075630,078694,078962","Cardiovascular Disease/Ophthalmology","Adrenergic Receptor","Neuronal Signaling","Betaxolol (SL 75212,Dextrobetaxolol) is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.",307.43,"63659-18-7",62,201.67,62,201.67,"http://selleckchem.com/products/betaxolol-betoptic.html","C18H29NO3","free base","SL 75212,Dextrobetaxolol","CC(C)NCC(O)COC1=CC=C(CCOCC2CC2)C=C1",2.577,2,2,11]
["S2092","Detomidine HCl","c4","L1300-07","in 10mM DMSO","DMF","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Adrenergic Receptor","Neuronal Signaling","Detomidine HCl(MPV 253AII) produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.",222.71,"90038-01-0",45,202.06,45,202.06,"http://selleckchem.com/products/detomidine-hcl.html","C12H14N2.HCl","HCl","MPV 253AII","Cl.CC1=C(C)C(=CC=C1)CC2=C[NH]C=N2",3.053,1,1,2]
["S2096","Almotriptan Malate","d4","L1300-07","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","078027,205171,205523","Neurological Disease","5-HT Receptor","Neuronal Signaling","Almotriptan Malate (LAS 31416) is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults.",469.55,"181183-52-8",94,200.19,"<1",0,"http://selleckchem.com/products/almotriptan-malate-axert.html","C17H25N3O2S.C4H6O5","Malate","LAS 31416","CN(C)CCC1=C[NH]C2=CC=C(C[S](=O)(=O)N3CCCC3)C=C12.OC(CC(O)=O)C(O)=O",-1.943,4,2,9]
["S2097","Ambrisentan","e4","L1300-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","208252,208354,208441,209509,210058,210715,210784","Cardiovascular Disease","Endothelin Receptor","GPCR & G Protein","Ambrisentan (LU-208075, BSF-208075) is a highly selective antagonist of the endothelin-1 type A receptor, used in the treatment of pulmonary arterial hypertension (PAH).",378.42,"177036-94-1",76,200.84,"<1",0,"http://selleckchem.com/products/ambrisentan.html","C22H22N2O4","free base","LU-208075, BSF-208075","COC(C(OC1=NC(=CC(=N1)C)C)C(O)=O)(C2=CC=CC=C2)C3=CC=CC=C3",3.659,5,0,7]
["S2098","Bexarotene (LGD1069)","f4","L1300-07","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","203174,209861,209886,210105","Cancer","Retinoid Receptor","Metabolism","Bexarotene (Targretin, LGD1069) is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.",348,"153559-49-0",8,22.99,"<1",0,"http://selleckchem.com/products/bexarotene.html","C24H28O2","free base","Targretin","CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(O)=O)C(C)(C)CCC2(C)C",6.405,1,0,3]
["S2099","Temocapril HCl","g4","L1300-07","in 10mM DMSO","PMDA,HMA","JP17;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","ACE,RAAS","Endocrinology & Hormones","Temocapril HCl (CS-622) is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.",513.07,"110221-44-8",103,200.75,"<1",0,"http://selleckchem.com/products/temocapril-hcl.html","C23H28N2O5S2.HCl","Hydrochloride","CS-622 HCl","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC2CSC(CN(CC(O)=O)C2=O)C3=CC=CS3",0.787,4,1,11]
["S2101","Gabexate Mesylate","h4","L1300-07","in 10mM DMSO","CFDA","KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease/Hematology","Serine Protease","Proteases","Gabexate Mesylate(FOY) is a serine protease inhibitor with IC50 of 0.19 μM which is used therapeutically in the treatment of pancreatitis and disseminated intravascular coagulation.",417.48,"56974-61-9",83,198.81,12,28.74,"http://selleckchem.com/products/gabexate-mesylate.html","C16H23N3O4.CH4O3S","Mesylate","FOY","CCOC(=O)C1=CC=C(OC(=O)CCCCCNC(N)=N)C=C1.C[S](O)(=O)=O",1.774,4,2,12]
["S2102","Rasagiline Mesylate","a5","L1300-07","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","201823,201889,201892,201899,201950,201970,201971,207004","Neurological Disease","MAO","Metabolism","Rasagiline Mesylate (TVP-1012,(R)-AGN1135 mesylate,TVP1012 mesylate) is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.",267.34,"161735-79-1",53,198.25,53,198.25,"http://selleckchem.com/products/rasagiline-mesylate.html","C12H13N.CH4O3S","Mesylate","TVP-1012,(R)-AGN1135 mesylate,TVP1012 mesylate","C[S](O)(=O)=O.C#CCNC1CCC2=CC=CC=C12",2.705,0,1,2]
["S2103","Naltrexone HCl","b5","L1300-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","074918,075274,075434,076264,090356,091205,207905","Psychotic disorders","Opioid Receptor","Neuronal Signaling","Naltrexone HCl(PTI-901) is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence.",377.86,"16676-29-2",14,37.05,14,37.05,"http://selleckchem.com/products/naltrexone-hcl.html","C20H23NO4.HCl","Hydrochloride","PTI-901","Cl.OC1=CC=C2CC3N(CCC45C(OC1=C24)C(=O)CCC35O)CC6CC6",2.039,2,1,2]
["S2104","Levosulpiride","c5","L1300-07","in 10mM DMSO","marketed in Italy","Martindale:The Extra Pharmacopoeia",null,"Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Levosulpiride(RV-12309,S-(-)-Sulpiride) is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent.",341.43,"23672-07-3",69,202.09,"<1",0,"http://selleckchem.com/products/levosulpiride-levogastrol.html","C15H23N3O4S","free base","RV-12309,S-(-)-Sulpiride","CCN1CCCC1CNC(=O)C2=C(OC)C=CC(=C2)[S](N)(=O)=O",0.704,4,2,6]
["S2105","Pantoprazole","d5","L1300-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;EP9.6;IP2010;CP2005;Martindale:The Extra Pharmacopoeia","022226,077056,077058,077619,078281,079197,090074,090296,090797,090807,090901,090970,091231,200794,200821,202038,202052,202882,203024,204400,205119,205675,208580,209463,209524,211368","Gastroenterology","ATPase,Proton Pump","Transmembrane Transporters","Pantoprazole (SKF96022, BY-1023) is a proton pump inhibitor drug that inhibits gastric acid secretion. It works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid.",383.37,"102625-70-7",76,198.24,"<1",0,"http://selleckchem.com/products/pantoprazole-protonix.html","C16H15F2N3O4S","free base","SKFSKF96022, BY-1023","COC1=C(OC)C(=NC=C1)C[S](=O)C2=NC3=CC=C(OC(F)F)C=C3[NH]2",2.737,6,1,7]
["S2108","Flunixin Meglumin","e5","L1300-07","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.2",null,"Inflammation/Neurological Disease","COX","Neuronal Signaling","Flunixin Meglumin(Banamine) is a potent inhibitor of the enzyme cyclooxygenase (COX) used as analgesic agent with anti-inflammatory and antipyretic activity.",491.46,"42461-84-7",98,199.41,98,199.41,"http://selleckchem.com/products/flunixin-meglumin.html","C14H11F3N2O2.C7H17NO5","Meglumin","Banamine","CNCC(O)C(O)C(O)C(O)CO.CC1=C(C=CC=C1NC2=NC=CC=C2C(O)=O)C(F)(F)F",-1.676,2,7,10]
["S2109","Imidapril HCl","f5","L1300-07","in 10mM DMSO","DMF,CFD,PMDA,HMA","JP17;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","ACE,RAAS","Endocrinology & Hormones","Imidapril HCl(TA-6366) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.",441.91,"89396-94-1",88,199.14,54,122.2,"http://selleckchem.com/products/imidapril-tanatril.html","C20H27N3O6.HCl","Hydrochloride","TA-6366","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C(CN(C)C2=O)C(O)=O",-1.197,5,1,10]
["S2111","Lapatinib (GW-572016)","g5","L1300-07","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","203007","Cancer","Autophagy,EGFR,Ferroptosis,HER2","Protein Tyrosine Kinase","Lapatinib (GW-572016, GSK572016, GW2016), used in the form of Lapatinib Ditosylate, is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively. Lapatinib induces ferroptosis and autophagic cell death.",581.06,"231277-92-2",100,172.1,"<1",0,"http://selleckchem.com/products/lapatinib.html","C29H26ClFN4O4S","free base","GSK572016, GW2016","C[S](=O)(=O)CCNCC1=CC=C(O1)C2=CC=C3N=CN=C(NC4=CC=C(OCC5=CC=CC(=C5)F)C(=C4)Cl)C3=C2",6.041,6,2,11]
["S2113","Cisatracurium Besylate","h5","L1300-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;EP9.4;BP2019;Martindale:The Extra Pharmacopoeia","200159,203183,203236,203238,205873,209132,209334,211668,211669","Neurological Disease","Adrenergic Receptor","Neuronal Signaling","Cisatracurium Besylate(51W89) is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.",1243.48,"96946-42-8",249,200.24,47,37.8,"http://selleckchem.com/products/cisatracurium-besylate-nimbex.html","C53H72N2O12.2C6H5O3S","Besylate","51W89","COC1=CC=C(CC2C3=CC(=C(OC)C=C3CC[N+]2(C)CCC(=O)OCCCCCOC(=O)CC[N+]4(C)CCC5=CC(=C(OC)C=C5C4CC6=CC=C(OC)C(=C6)OC)OC)OC)C=C1OC.[O-][S](=O)(=O)C7=CC=CC=C7.[O-][S](=O)(=O)C8=CC=CC=C8",3.646,12,0,28]
["S2114","Dronedarone HCl","a6","L1300-07","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","205682,205895,205903","Cardiovascular Disease","Calcium Channel,Potassium Channel,Sodium Channel","Transmembrane Transporters","Dronedarone HCl (SR33589) is a multichannel blocker targeting potassium channel, sodium channel and calcium channel, used as an antiarrhythmic drug for treatment of atrial fibrillation (AF).",593.22,"141625-93-6",80,134.86,"<1",0,"http://selleckchem.com/products/dronedarone-hcl-multaq.html","C31H44N2O5S.HCl","HCl","SR33589","Cl.CCCCN(CCCC)CCCOC1=CC=C(C=C1)C(=O)C2=C(CCCC)OC3=CC=C(N[S](C)(=O)=O)C=C23",7.397,5,1,18]
["S2116","Conivaptan HCl","b6","L1300-07","in 10mM DMSO","FDA,NDC","Martindale:The Extra Pharmacopoeia","021697,022016","Hematology","Vasopressin Receptor","GPCR & G Protein","Conivaptan HCl(YM 087) is an orally active, non-peptide, vasopressin V1A and V2 receptor antagonist, used in the treatment of euvolemic and hypervolemic hyponatremia.",535.04,"168626-94-6",107,199.99,"<1",0,"http://selleckchem.com/products/conivaptan-hcl-vaprisol.html","C32H26N4O2.HCl","HCl","YM 087","Cl.CC1=NC2=C([NH]1)C3=C(C=CC=C3)N(CC2)C(=O)C4=CC=C(NC(=O)C5=C(C=CC=C5)C6=CC=CC=C6)C=C4",5.68,3,2,4]
["S2118","Ibutilide Fumarate","c6","L1300-07","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","090240,090643,090924","Cardiovascular Disease","Sodium Channel","Transmembrane Transporters","Ibutilide Fumarate (U-70226E,Corvert Fumarate) is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells.",885.23,"122647-32-9",89,100.54,89,100.54,"http://selleckchem.com/products/ibutilide-fumarate.html","(C20H36N2O3S)2.C4H4O4","Fumarate","U-70226E,Corvert Fumarate","CCCCCCCN(CC)CCCC(O)C1=CC=C(N[S](C)(=O)=O)C=C1.CCCCCCCN(CC)CCCC(O)C2=CC=C(N[S](C)(=O)=O)C=C2.OC(=O)\\C=C\\C(O)=O",1.954,6,4,30]
["S2119","Probucol","d6","L1300-07","in 10mM DMSO","FDA,DMF,CFDA","USP42-NF37;JP17;Martindale:The Extra Pharmacopoeia;CP2005","017535","Cardiovascular Disease","LDL","Metabolism","Probucol (DH-581) is an anti-hyperlipidemic drug by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.",516.84,"23288-49-5",103,199.29,"<1",0,"http://selleckchem.com/products/probucol.html","C31H48O2S2","free base","DH-581","CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SC(C)(C)SC2=CC(=C(O)C(=C2)C(C)(C)C)C(C)(C)C",9.779,0,2,8]
["S2120","Arbidol HCl","e6","L1300-07","in 10mM DMSO","CFDA",null,null,"Infection","Influenza Virus","Microbiology","Arbidol HCl (Umifenovir) is a broad-spectrum antiviral compound that blocks viral fusion, used in treatment of influenza and other respiratory viral infections.",513.88,"131707-23-8",103,200.44,"<1",0,"http://selleckchem.com/products/Arbidol-hcl.html","C22H25BrN2O3S.HCl","Hydrochloride","Umifenovir hydrochloride, Arbidol hydrochloride","Cl.CCOC(=O)C1=C(CSC2=CC=CC=C2)[N](C)C3=CC(=C(O)C(=C13)CN(C)C)Br",5.698,2,1,8]
["S2123","Dextrose","f6","L1300-07","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP38-NF33;IP2010","004589","Metabolic Disease","Others","Others","Dextrose (D-glucose), a simple sugar (monosaccharide), is an important carbohydrate in biology.",180.16,"50-99-7",36,199.82,36,199.82,"http://selleckchem.com/products/Dextrose(D-glucose).html","C6H12O6","free base","D-glucose","OCC(O)C(O)C(O)C(O)C=O",-2.791,1,5,5]
["S2124","Xylose","g6","L1300-07","in 10mM DMSO","FDA,DMF,HMA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","018856","Others","Others","Others","Xylose(Wood sugar) is a sugar first isolated from wood.",150.13,"25990-60-7, 58-86-6",30,199.83,30,199.83,"http://selleckchem.com/products/Xylose.html","C5H10O5","free base","Wood sugar","OCC(O)C(O)C(O)C=O",-2.28,1,4,4]
["S2125","Mestranol","h6","L1300-07","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","070758,070759","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Mestranol is the 3-methyl ether of ethinyl estradiol, which is a potent estrogen receptor agonist and used as oral contraceptives.",310.43,"72-33-3",15,48.32,"<1",0,"http://selleckchem.com/products/Mestranol.html","C21H26O2","free base","N/A","COC1=CC2=C(C=C1)C3CCC4(C)C(CCC4(O)C#C)C3CC2",5.112,1,0,1]
["S2126","Naftopidil","a7","L1300-07","in 10mM DMSO","DMF,CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Others","Adrenergic Receptor","Neuronal Signaling","Naftopidil (KT-611) is a selective α1-adrenergic receptor antagonist with Ki of 3.7 nM, 20 nM, and 1.2 nM for α1a, α1b, and α1d, respectively, used for the treatment of benign prostatic hyperplasia.",392.49,"57149-07-2",79,201.28,"<1",0,"http://selleckchem.com/products/Naftopidil(Flivas).html","C24H28N2O3","Free Base","KT-611","COC1=CC=CC=C1N2CCN(CC2)CC(O)COC3=C4C=CC=CC4=CC=C3",3.962,2,1,7]
["S2127","S-(+)-Rolipram","b7","L1300-07","in 10mM DMSO","DMF",null,null,"Psychotic disorders","PDE","Metabolism","S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.",275.34,"85416-73-5",55,199.75,"<1",0,"http://selleckchem.com/products/sRolipram.html","C16H21NO3","free base","N/A","COC1=C(OC2CCCC2)C=C(C=C1)C3CNC(=O)C3",2.349,3,1,4]
["S2128","Bazedoxifene (WAY-140424) HCl","c7","L1300-07","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","022247","Cancer","Estrogen/progestogen Receptor","Endocrinology & Hormones","Bazedoxifene HCl (WAY-140424, TSE-424) is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of  23 nM and 89 nM, respectively.",507.06,"198480-56-7",101,199.19,"<1",0,"http://selleckchem.com/products/bazedoxifene-hcl.html","C30H34N2O3.HCl","Hydrochloride","TSE-424","Cl.CC1=C([N](CC2=CC=C(OCCN3CCCCCC3)C=C2)C4=CC=C(O)C=C14)C5=CC=C(O)C=C5",7.602,1,2,7]
["S2130","Atropine sulfate monohydrate","d7","L1300-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.3;BP2019;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia;CP2005","071295,020056,206289,209260","Others","AChR,ADC Cytotoxin","Neuronal Signaling","Atropine sulfate monohydrate is a competitive antagonist for the muscarinic acetylcholine receptor, used to decrease the production of saliva and secretions of the airway prior to surgery.",694.83,"5908-99-6",139,200.05,139,200.05,"http://selleckchem.com/products/Atropine-sulfate-monohydrate.html","2(C17H23NO3).H2O.H2SO4","Sulfate monohydrate","N/A","O.CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN4C5CCC4CC(C5)OC(=O)C(CO)C6=CC=CC=C6.O[S](O)(=O)=O",2.628,4,2,10]
["S2131","Roflumilast (B9302-107)","e7","L1300-07","in 10mM DMSO","FDA,DMF,EMA,NDC","Martindale:The Extra Pharmacopoeia","208180,208213,208236,208247,208256,208257,208272,208299","Inflammation/Respiratory Disease","PDE","Metabolism","Roflumilast (APTA 2217, B9302-107, BY 217, BYK 20869) is a selective inhibitor of PDE4 with IC50 of 0.2-4.3 nM in a cell-free assay.",403.21,"162401-32-3",81,200.89,"<1",0,"http://selleckchem.com/products/Roflumilast(Daxas).html","C17H14Cl2F2N2O3","free base","APTA 2217, B9302-107, BY 217, BYK 20869","FC(F)OC1=CC=C(C=C1OCC2CC2)C(=O)NC3=C(Cl)C=NC=C3Cl",4.402,4,1,7]
["S2151","Sonidegib (NVP-LDE225)","f7","L1300-07","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"205266","Cancer","Hedgehog/Smoothened","Stem Cells & Wnt","Sonidegib (Erismodegib, NVP-LDE225) is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human) in cell-free assays, respectively. Phase 3.",485.5,"956697-53-3",97,199.79,"<1",0,"http://selleckchem.com/products/LDE225(NVP-LDE225).html","C26H26F3N3O3","free base","Erismodegib","CC1CN(CC(C)O1)C2=CC=C(NC(=O)C3=C(C)C(=CC=C3)C4=CC=C(OC(F)(F)F)C=C4)C=N2",6.732,4,1,6]
["S2154","Dabigatran (BIBR-1048) etexilate","g7","L1300-07","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","207984,208046,208057","Cardiovascular Disease","Thrombin","Proteases","Dabigatran Etexilate (BIBR-1048) is the prodrug of dabigatran, a potent, nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule.",627.73,"211915-06-9",126,200.72,"<1",0,"http://selleckchem.com/products/BIBR-1048(Dabigatran-etexilate).html","C34H41N7O5","free base","BIBR-1048","CCCCCCOC(=O)N=C(N)C1=CC=C(NCC2=NC3=C(C=CC(=C3)C(=O)N(CCC(=O)OCC)C4=CC=CC=N4)[N]2C)C=C1",5.751,8,2,17]
["S2159","Tebipenem Pivoxil","h7","L1300-07","in 10mM DMSO","marketed in Japan",null,null,"Infection","Antibiotics","Microbiology","Tebipenem pivoxil (L-084, ME1211,TBPM-PI,LJC 11036) is an oral carbapenem antibiotic, use to treat otolaryngologic and respiratory infections.",497.63,"161715-24-8",99,198.94,"<1",0,"http://selleckchem.com/products/Tebipenem-pivoxil(L-084).html","C22H31N3O6S2","free base","L-084, ME1211,TBPM-PI,LJC 11036","CC(O)C1C2C(C)C(=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C)SC3CN(C3)C4=NCCS4",1.782,6,1,10]
["S2167","Bazedoxifene (TSE-424) acetate","a8","L1300-07","in 10mM DMSO","FDA,DMF,PMDA","Martindale:The Extra Pharmacopoeia","022247","Cancer","Estrogen/progestogen Receptor","Endocrinology & Hormones","Bazedoxifene Acetate (WAY-140424,TSE-424 acetate) is a third generation selective estrogen receptor modulator (SERM).",530.65,"198481-33-3",100,188.45,"<1",0,"http://selleckchem.com/products/Bazedoxifene-acetate.html","C30H34N2O3.C2H4O2","Acetate","WAY-140424,TSE-424 acetate","CC(O)=O.CC1=C([N](CC2=CC=C(OCCN3CCCCCC3)C=C2)C4=CC=C(O)C=C14)C5=CC=C(O)C=C5",3.981,2,2,7]
["S2169","Rosuvastatin (ZD4522) calcium","b8","L1300-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","079145,079161,079166,079167,079168,079169,079170,079171,079172,201619,205587,206381,206434,206465,206513,207062,207375,207408,207453,207616,207626,207752,208850,208898","Cardiovascular Disease","COVID-19,HMG-CoA Reductase","Metabolism","Rosuvastatin Calcium (ZD4522 calcium) is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM in a cell-free assay.",500.57,"147098-20-2",100,199.77,"<1",0,"http://selleckchem.com/products/Rosuvastatin-calcium(Crestor).html","C22H28FN3O6S.1/2Ca","Calcium salt","ZD4522 calcium","[Ca++].CC(C)C1=C(\\C=C\\C(O)CC(O)CC([O-])=O)C(=NC(=N1)N(C)[S](C)(=O)=O)C2=CC=C(F)C=C2.CC(C)C3=C(\\C=C\\C(O)CC(O)CC([O-])=O)C(=NC(=N3)N(C)[S](C)(=O)=O)C4=CC=C(F)C=C4",1.906,8,4,20]
["S2173","Telotristat Etiprate (LX 1606 Hippurate)","c8","L1300-07","in 10mM DMSO","FDA",null,"208794","Gastroenterology","Hydroxylase","Metabolism","Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. Phase 3.",754.15,"1137608-69-5",100,132.6,"<1",0,"http://selleckchem.com/products/telotristat-etiprate-lx-1606-hippurate.html","C27H26ClF3N6O3.C9H9NO3","Hippuric acid","N/A","CCOC(=O)C(N)CC1=CC=C(C=C1)C2=CC(=NC(=N2)N)OC(C3=CC=C(Cl)C=C3[N]4C=CC(=N4)C)C(F)(F)F.OC(=O)CNC(=O)C5=CC=CC=C5",3.747,8,3,14]
["S2177","Dichlorphenamide","d8","L1300-07","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","011366,011366","Ophthalmology","Carbonic Anhydrase","Metabolism","Dichlorphenamide (Diclofenamide) is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class.",305.16,"120-97-8",61,199.89,0,0,"http://www.selleckchem.com/products/Dichlorphenamide(Diclofenamide).html","C6H6Cl2N2O4S2","Free Base","Diclofenamide","N[S](=O)(=O)C1=CC(=C(Cl)C(=C1)[S](N)(=O)=O)Cl",0,0,0,0]
["S2180","Ixazomib (MLN2238)","e8","L1300-07","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"208462","Cancer","Autophagy,Proteasome","Proteases","Ixazomib (MLN2238) inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM in cell-free assays, respectively, also inhibits the caspase-like (β1) and trypsin-like (β2) proteolytic sites, with IC50 of 31 and 3500 nM. Ixazomib (MLN2238) induces autophagy. Phase 3.",361.03,"1072833-77-2",72,199.43,"<1",0,"http://selleckchem.com/products/MLN-2238.html","C14H19BCl2N2O4","Free Base","N/A","CC(C)CC(NC(=O)CNC(=O)C1=C(Cl)C=CC(=C1)Cl)B(O)O",3.344,2,2,7]
["S2181","Ixazomib Citrate (MLN9708) Analogue","f8","L1300-07","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"208462","Cancer","Autophagy,Proteasome","Proteases","Ixazomib Citrate (MLN9708) Analogue is the analogue of Ixazomib Citrate (MLN9708) from WO2016165677A1. Ixazomib Citrate (MLN9708) immediately hydrolyzed to Ixazomib (MLN2238), the biologically active form, on exposure to aqueous solutions or plasma. Ixazomib (MLN2238) inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50/Ki of 3.4 nM/0.93 nM in cell-free assays, less potent to β1 and little activity to β2. Ixazomib (MLN2238) induces autophagy. Phase 3.",517.12,"1201902-80-8",100,193.38,"<1",0,"http://selleckchem.com/products/MLN9708.html","C20H23BCl2N2O9","free base","N/A","CC(C)CC(NC(=O)CNC(=O)C1=C(Cl)C=CC(=C1)Cl)B2OC(=O)CC(CC(O)=O)(O2)C(O)=O",3.497,7,2,10]
["S2183","Infigratinib (BGJ398)","g8","L1300-07","in 10mM DMSO","FDA，EMA",null,"005361,214622","Cancer","FGFR","Angiogenesis","Infigratinib (BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM in cell-free assays, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes. Phase 2.",560.48,"872511-34-7",27,48.17,"<1",0,"http://www.selleck.cn/products/bgj398-nvp-bgj398.html","C26H31Cl2N7O3","Free Base","NVP-BGJ398","CCN1CCN(CC1)C2=CC=C(NC3=NC=NC(=C3)N(C)C(=O)NC4=C(Cl)C(=CC(=C4Cl)OC)OC)C=C2",5.342,5,2,8]
["S2188","Phenprocoumon","h8","L1300-07","in 10mM DMSO","FDA,HMA","Martindale the Extra Pharmacopoei","011228","Hematology","5-alpha Reductase","Angiogenesis","Phenprocoumon (Marcoumar, Marcumar and Falithrom,Ro 1-4849) is a vitamin K reductase with an IC50 of 1 μM",280.32,"435-97-2,53621-47-9 (sodium salt)",56,199.77,"<1",0,"http://www.selleck.cn/products/Phenprocoumon(Marcumar).html","C18H16O3","free base","Marcoumar, Marcumar and Falithrom,Ro 1-4849","CCC(C1=CC=CC=C1)C2=C(O)C3=CC=CC=C3OC2=O",4.004,2,1,3]
["S2199","Aliskiren Hemifumarate","a9","L1300-07","in 10mM DMSO","FDA,DMF,NDC",null,"206665","Cardiovascular Disease","RAAS","Endocrinology & Hormones","Aliskiren hemifumarate(CGP 60536 hemifumarate, CGP60536B hemifumarate, SPP 100 hemifumarate) is a direct renin inhibitor with IC50 of 1.5 nM.",609.83,"173334-58-2",100,163.98,100,163.98,"http://selleckchem.com/products/Aliskiren-hemifumarate.html","C30H53N3O6.1/2C4H4O4","fumarate salt","CGP 60536 hemifumarate, CGP60536B hemifumarate, SPP 100 hemifumarate","COCCCOC1=C(OC)C=CC(=C1)CC(CC(N)C(O)CC(C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C.COCCCOC2=C(OC)C=CC(=C2)CC(CC(N)C(O)CC(C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C.OC(=O)\\C=C\\C(O)=O",1.735,12,8,40]
["S2217","Irinotecan (CPT-11) HCl Trihydrate","c9","L1300-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.3;BP2018;IP2010;Martindale:The Extra Pharmacopoeia","077219,077260,077776,077915,077994,078122,078188,078589,078753,078796,078805,078953,079068,090016,090101,090137,090393,090675,090726,091032,200771,203054,203380,206935,208718","Cancer","Topoisomerase","DNA Damage/DNA Repair","Irinotecan (CPT-11) prevents DNA from unwinding by inhibition of topoisomerase 1.",677.18,"136572-09-3",100,147.67,1,1.48,"http://selleckchem.com/products/Irinotecan-Hcl-Trihydrate-Campto.html","C33H38N4O6.HCl.3H2O","HCl & trihydrat","CPT-11 HCl Trihydrate","O.O.O.Cl.CCC1=C2CN3C(=O)C4=C(C=C3C2=NC5=CC=C(OC(=O)N6CCC(CC6)N7CCCCC7)C=C15)C(O)(CC)C(=O)OC4",3.446,6,0,5]
["S2219","Momelotinib (CYT387)","d9","L1300-07","in 10mM DMSO","NDC;FDA",null,null,"Cancer","Apoptosis related,Autophagy,JAK","JAK/STAT","Momelotinib (CYT387, LM-1149 , CYT11387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3. Momelotinib (CYT387) induces apoptosis and autophagy. Phase 3.",414.46,"1056634-68-4",74,178.55,"<1",0,"http://selleckchem.com/products/Cyt387.html","C23H22N6O2","free base","LM-1149 , CYT11387","O=C(NCC#N)C1=CC=C(C=C1)C2=NC(=NC=C2)NC3=CC=C(C=C3)N4CCOCC4",2.857,4,2,6]
["S2226","Idelalisib","e9","L1300-07","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"205858，206545","Cancer/Hematology","Autophagy,PI3K","PI3K/Akt/mTOR","Idelalisib (CAL-101, GS-1101) is a selective p110δ inhibitor with IC50 of 2.5 nM in cell-free assays; shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR. Idelalisib also stimulates autophagy.",415.42,"870281-82-6",83,199.8,"<1",0,"http://selleckchem.com/products/CAL-101.html","C22H18FN7O","free base","CAL-101, GS-1101","CCC(NC1=C2N=C[NH]C2=NC=N1)C3=NC4=CC=CC(=C4C(=O)N3C5=CC=CC=C5)F",3.624,5,2,5]
["S2229","Eltrombopag (SB497115) Olamine","f9","L1300-07","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia","022291，207027","Immunology","TpoR","Immunology & Inflammation","Eltrombopag Olamine (SB-497115-GR, Revolade, Promacta,Promacta Olamine) is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR).",564.63,"496775-62-3",89,157.63,"<1",0,"http://selleckchem.com/products/Eltrombopag-SB-497115-GR.html","C29H36N6O6","diolamine","SB-497115-GR, Revolade, Promacta,Promacta Olamine","CC1=CC=C(C=C1C)N2N=C(C)C(=N/NC3=CC=CC(=C3O)C4=CC(=CC=C4)C(O)=O)/C2=O.NCCO.NCCO",-0.151,4,6,7]
["S2233","Esomeprazole sodium","g9","L1300-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","EP9.7;Martindale:The Extra Pharmacopoeia","200882,202686,204657,205379,207181","Gastrointestinal Disease","ATPase","Transmembrane Transporters","Esomeprazole Sodium((S)-Omeprazole sodium, (-)-Omeprazole sodium) is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.",367.4,"161796-78-7",73,198.69,73,198.69,"http://selleckchem.com/products/esomeprazole-sodium.html","C17H18N3O3S.Na","Sodium salt","(S)-Omeprazole sodium, (-)-Omeprazole sodium","COC1=CC=C2[N]([Na])C(=NC2=C1)[S](=O)CC3=NC=C(C)C(=C3C)OC",3.008,5,0,5]
["S2246","Abiraterone Acetate (CB7630)","h9","L1300-07","in 10mM DMSO","FDA,DMF,NDC,PMDA","USP42-NF37","208327,208339,208371,208380,208432,208446,208453,209227","Cancer","Androgen Receptor,P450 (e.g. CYP17)","Metabolism","Abiraterone Acetate (CB7630, CB-7630) is an acetate salt form of Abiraterone which is a steroidal cytochrome CYP17 inhibitor with IC50 of 72 nM in a cell-free assay. Abiraterone acetate is an oral androgen biosynthesis inhibitor.",391.55,"154229-18-2",20,51.08,"<1",0,"http://www.selleck.cn/products/Abiraterone-Acetate-CB7630.html","C26H33NO2","Acetate","CB7630, CB-7630","CC(=O)OC1CCC2(C)C3CCC4(C)C(CC=C4C5=CC=CN=C5)C3CC=C2C1",4.602,3,0,3]
["S2250","(-)-Epigallocatechin Gallate","a10","L1300-07","in 10mM DMSO","DMF",null,null,"Cardiovascular Disease/Endocrinology/Metabolic Disease","DNA Methyltransferase,EGFR,Fatty Acid Synthase,HER2,Telomerase","DNA Damage/DNA Repair","(-)-Epigallocatechin Gallate(EGCG) is the main catechin extraction of green tea that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 receptors. ECGG inhibits fatty acid synthase and glutamate dehydrogenase activity.",458.37,"989-51-5",72,157.08,23,50.18,"http://selleckchem.com/products/(-)-Epigallocatechin-gallate.html","C22H18O11","free base","EGCG","OC1=CC2=C(CC(OC(=O)C3=CC(=C(O)C(=C3)O)O)C(O2)C4=CC(=C(O)C(=C4)O)O)C(=C1)O",3.097,3,8,4]
["S2256","4-Methylumbelliferone (4-MU)","b10","L1300-07","in 10mM DMSO","CFDA","BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia",null,"Cancer","Others","Others","4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM.",176.17,"90-33-5",35,198.67,"<1",0,"http://selleckchem.com/products/4-Methylumbelliferone(4-MU).html","C10H8O3","free base","N/A","CC1=CC(=O)OC2=C1C=CC(=C2)O",2.104,2,1,0]
["S2258","Esculin","c10","L1300-07","in 10mM DMSO",null,"BP2019;EP9.2",null,"Angiology","Others","Others","Esculin (Aesculin) is a glucoside found in horse chestnuts.",340.28,"531-75-9",68,199.84,2,5.88,"http://selleckchem.com/products/Aesculin(Esculin).html","C15H16O9","free base","Aesculin","OCC1OC(OC2=C(O)C=C3OC(=O)C=CC3=C2)C(O)C(O)C1O",-0.514,4,5,3]
["S2260","Amygdalin","d10","L1300-07","in 10mM DMSO","NDC","Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Amygdalin is a glycoside initially isolated from the seeds of the tree Prunus dulcis, also known as bitter almonds.",457.43,"29883-15-6",91,198.94,"<1",0,"http://selleckchem.com/products/Amygdalin.html","C20H27NO11","free base",0,"OCC1OC(OCC2OC(OC(C#N)C3=CC=CC=C3)C(O)C(O)C2O)C(O)C(O)C1O",-2.403,4,7,7]
["S2261","Andrographolide","e10","L1300-07","in 10mM DMSO","CFDA","BP2019;EP9.2",null,"Inflammation/Gastrointestinal Disease","NF-κB","NF-κB","Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata.",350.45,"5508-58-7",70,199.74,"<1",0,"http://selleckchem.com/products/Andrographolide.html","C20H30O5","free base","N/A","CC1(CO)C(O)CCC2(C)C(C\\C=C\\3C(O)COC3=O)C(=C)CCC12",2.056,2,3,3]
["S2262","Apigenin (LY 080400)","f10","L1300-07","in 10mM DMSO",null,"EP9.2;BP2017",null,"Cancer/Cardiovascular Disease/Infection","P450 (e.g. CYP17)","Metabolism","Apigenin (NSC 83244, LY 080400) is a potent P450 inhibitor for CYP2C9 with Ki of 2 μM.",270.24,"520-36-5",54,199.82,"<1",0,"http://selleckchem.com/products/Apigenin.html","C15H10O5","free base","NSC 83244","OC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(O)C=C3O",2.41,2,3,1]
["S2263","Arbutin","g10","L1300-07","in 10mM DMSO","NDC","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Others","Tyrosinase","Proteases","Arbutin (Uva, p-Arbutin, β-Arbutin) is a tyrosinase inhibitor with IC50 of 0.9 mM and 0.7 mM for Monophenolase and Diphenolase, respectively.",272.25,"497-76-7",55,202.02,55,202.02,"http://selleckchem.com/products/Arbutin(Uva,-p-Arbutin).html","C12H16O7","free base","Uva,p-Arbutin, β-Arbutin","OCC1OC(OC2=CC=C(O)C=C2)C(O)C(O)C1O",-0.584,2,5,3]
["S2264","Artemether","h10","L1300-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Ph.Int_6th;Martindale:The Extra Pharmacopoeia","022268","Infection/Parasitology","ADC Cytotoxin,Anti-infection","Microbiology","Artemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria.",298.37,"71963-77-4",60,201.09,"<1",0,"http://selleckchem.com/products/Artemether(SM-224).html","C16H26O5","free base","SM-224, CGP 56696","COC1OC2OC3(C)CCC4C(C)CCC(C1C)C24OO3",2.029,5,0,1]
["S2265","Artesunate (WR-256283)","a11","L1300-07","in 10mM DMSO","DMF,CFDA","Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","ADC Cytotoxin,STAT","JAK/STAT","Artesunate (WR-256283) is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69. It is a potential inhibitor of STAT-3 and exhibits selective cytotoxicity of cancer cells over normal cells in vitro; A potent inhibitor of EXP1.",384.42,"88495-63-0",77,200.3,"<1",0,"http://selleckchem.com/products/Artesunate.html","C19H28O8","free base","WR-256283","CC1CCC2C(C)C(OC3OC4(C)CCC1C23OO4)OC(=O)CCC(O)=O",1.845,7,0,5]
["S2266","Asiatic Acid","b11","L1300-07","in 10mM DMSO","NDC",null,null,"Cancer/Inflammation","p38 MAPK","MAPK","Asiatic acid (Dammarolic acid, Asiantic acid) is the aglycone of asiaticoside isolated from the plant Centella asiatica, commonly used in wound healing.",488.7,"464-92-6",97,198.49,"<1",0,"http://selleckchem.com/products/Asiatic-acid.html","C30H48O5","free base","Dammarolic acid, Asiantic acid","CC1CCC2(CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(CO)C5CCC34C)C2C1C)C(O)=O",4.435,1,3,2]
["S2268","Baicalein","c11","L1300-07","in 10mM DMSO","CFDA",null,null,"Cardiovascular Disease","P450 (e.g. CYP17),PREP","Metabolism","Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor.",270.24,"491-67-8",54,199.82,"<1",0,"http://selleckchem.com/products/Baicalein.html","C15H10O5","free base","N/A","OC1=C(O)C(=C2C(=O)C=C(OC2=C1)C3=CC=CC=C3)O",2.41,2,3,1]
["S2269","Baicalin (NSC-661431)","d11","L1300-07","in 10mM DMSO","CFDA","BP2019;EP9.2",null,"Infection/Inflammation","GABA Receptor,PREP","Neuronal Signaling","Baicalin (NSC-661431) is a known prolyl endopeptidase inhibitor and affects the GABA receptors.",446.36,"21967-41-9",89,199.39,"<1",0,"http://selleckchem.com/products/Baicalin.html","C21H18O11","free base","N/A","OC1C(O)C(OC(C1O)C(O)=O)OC2=C(O)C(=C3C(=O)C=C(OC3=C2)C4=CC=CC=C4)O",0.608,5,5,4]
["S2270","Bergenin","e11","L1300-07","in 10mM DMSO","CFDA",null,null,"Inflammation/Respiratory Disease","Others","Others","Bergenin (Cuscutin) is trihydroxybenzoic acid glycoside and the C-glycoside of 4-O-methyl gallic acid.",328.27,"477-90-7",66,201.05,"<1",0,"http://selleckchem.com/products/Bergenin-(Cuscutin).html","C14H16O9","free base","Cuscutin","COC1=C(O)C2=C(C=C1O)C(=O)OC3C(O)C(O)C(CO)OC23",-0.849,4,5,2]
["S2271","Berberine chloride (NSC 646666)","f11","L1300-07","in 10mM DMSO","PMDA","BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","Anti-infection,Apoptosis related,Autophagy,Bcl-2,Caspase,IAP,JNK,p38 MAPK,P450 (e.g. CYP17),PARP,ROS,Topoisomerase","Microbiology","Berberine chloride (NSC 646666, Natural Yellow 18) is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. Berberine chloride decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. Berberine chloride induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. Berberine chloride is a dual topoisomerase I and II inhibitor. Berberine chloride is also a potential autophagy modulator.",371.81,"633-65-8",40,107.58,"<1",0,"http://selleckchem.com/products/Berberine-Hydrochloride.html","C20H18NO4.Cl","chloride","Natural Yellow 18 chloride","[Cl-].COC1=CC=C2C=C3C4=C(CC[N+]3=CC2=C1OC)C=C5OCOC5=C4",1.289,4,0,2]
["S2277","Caffeic Acid","g11","L1300-07","in 10mM DMSO","CFDA,NDC","BP2019;EP9.2;CP2005",null,"Hematology","Lipoxygenase,TRP Channel","Transmembrane Transporters","Caffeic acid is a hydroxycinnamic acid, a naturally occurring organic compound. Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO).",180.16,"331-39-5",36,199.82,"<1",0,"http://selleckchem.com/products/Caffeic-acid.html","C9H8O4","free base","N/A","OC(=O)/C=C/C1=CC=C(O)C(=C1)O",1.443,1,2,2]
["S2280","Chlorogenic Acid","h11","L1300-07","in 10mM DMSO",null,"USP42-NF37 ;BP2019;EP9.2",null,"Cancer","Others","Others","Chlorogenic acid (NSC 407296, Heriguard) is a hydroxycinnamic acid and a member of a family of naturally occurring organic compounds.",354.31,"327-97-9",71,200.39,18,50.8,"http://selleckchem.com/products/Chlorogenic-acid.html","C16H18O9","free base","NSC 407296, Heriguard","OC1CC(O)(CC(OC(=O)\\C=C\\C2=CC(=C(O)C=C2)O)C1O)C(O)=O",-0.34,3,4,5]
["S2282","Cinchonidine","a2","L1300-08","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.2",null,"Others","Anti-infection,Serotonin Transporter","Microbiology","Cinchonidine is an alkaloid used in asymmetric synthesis in organic chemistry.",294.39,"485-71-2",59,200.41,"<1",0,"http://selleckchem.com/products/Cinchonidine.html","C19H22N2O","free base","N/A","OC(C1CC2CCN1CC2C=C)C3=CC=NC4=CC=CC=C34",2.75,1,1,3]
["S2283","Cinchonine(LA40221)","b2","L1300-08","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.2",null,"Cancer","5-alpha Reductase","Angiogenesis","Cinchonine (LA40221) is an alkaloid and a stereoisomer and pseudo-enantiomer of cinchonidine.",294.4,"118-10-5",9,30.57,0,0,"http://selleckchem.com/products/cinchonine.html","C19H22N2O","free base","N/A","OC(C1CC2CCN1CC2C=C)C3=CC=NC4=CC=CC=C34",2.75,1,1,3]
["S2284","Colchicine (NSC 757)","c2","L1300-08","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.4;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","203976,204461,204711,208678,211250,211519","Metabolic Disease","Microtubule Associated","Cell Cycle","Colchicine (NSC 757, Colchineos, Colchisol, Colcin) is a microtubule polymerization inhibitor with an IC50 of 3 nM.",399.44,"64-86-8",80,200.28,80,200.28,"http://selleckchem.com/products/colchicine.html","C22H25NO6","free base","Colchineos, Colchisol, Colcin,NSC 757","COC1=CC=C2C(=CC1=O)C(CCC3=C2C(=C(OC)C(=C3)OC)OC)NC(C)=O",2.044,6,1,5]
["S2286","Cyclosporin A (NSC 290193)","d2","L1300-08","in 10mM DMSO","FDA, EMA, HMA, CFDA, NDC, PMDA","Martindale the Extra Pharmacopoei, EP10.2, USP43-NF38, Ph.Int_6th, JP17",210913,"Immunology","Antineoplastic and Immunosuppressive Antibiotics,Complement System,Immunology & Inflammation related,phosphatase","Immunology & Inflammation","Cyclosporin A (Cyclosporine A, Cyclosporine, Ciclosporin, CsA,NSC 290193) is an immunosuppressive agent, binds to the cyclophilin and then inhibits calcineurin with IC50 of 7 nM in a cell-free assay, widely used in organ transplantation to prevent rejection.",1202.61,"59865-13-3",100,83.15,"<1",0,"http://selleckchem.com/products/Cyclosporin-A(Cyclosporine-A).html","C62H111N11O12","free base","Cyclosporine A, Cyclosporine, Ciclosporin, CsA,NSC 290193","CCC1NC(=O)C(C(O)C(C)C\\C=C\\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C",4.333,11,5,15]
["S2287","Cytisine","e2","L1300-08","in 10mM DMSO","NDC,HMA","Martindale:The Extra Pharmacopoeia",null,"Psychotic disorders","AChR","Neuronal Signaling","Cytisine (Baphitoxine, Sophorine) is a nicotinic acetylcholine receptor agonist.",190.24,"485-35-8",38,199.75,38,199.75,"http://selleckchem.com/products/Cytisine(Baphitoxine,-Sophorine).html","C11H14N2O","free base","Baphitoxine,Sophorine","O=C1C=CC=C2C3CNCC(C3)CN12",-0.338,1,1,0]
["S2289","Daidzin","f2","L1300-08","in 10mM DMSO","CFDA","BP2019;EP9.2",null,"Cancer/Cardiovascular Disease/Endocrinology","Dehydrogenase","Metabolism","Daidzin (Daidzoside, Daidzein 7-O-glucoside, Daidzein 7-glucoside), a natural organic compound in the class of phytochemicals known as isoflavones, is a potent and selective inhibitor of human mitochondrial aldehyde dehydrogenase and inhibits ALDH-I selectively (Ki=20 nM); at least 500 times less effective against ALDH-Ⅱ, the cytosolic isozyme (Ki=10 μM).",416.38,"552-66-9",83,199.34,"<1",0,"http://selleckchem.com/products/Daidzin.html","C21H20O9","Free Base","Daidzoside, Daidzein 7-O-glucoside, Daidzein 7-glucoside","OCC1OC(OC2=CC3=C(C=C2)C(=O)C(=CO3)C4=CC=C(O)C=C4)C(O)C(O)C1O",0.452,4,5,4]
["S2290","Dihydroartemisinin (DHA)","g2","L1300-08","in 10mM DMSO","CFDA",null,null,"Infection","Apoptosis related,Autophagy,NF-κB","NF-κB","Dihydroartemisinin (DHA, Dihydroqinghaosu, β-Dihydroartemisinin, Artenimol) is a semi-synthetic derivative of artemisinin and isolated from the traditional Chinese herb Artemisia annua. Dihydroartemisinin induces autophagy and apoptosis by suppressing NF-κB activation.",284.35,"71939-50-9",56,196.94,"<1",0,"http://selleckchem.com/products/Dihydroartemisinin(DHA).html","C15H24O5","free base","Dihydroqinghaosu, β-Dihydroartemisinin, Artenimol","CC1CCC2C(C)C(O)OC3OC4(C)CCC1C23OO4",1.621,4,0,0]
["S2293","DL-Carnitine HCl","h2","L1300-08","in 10mM DMSO","DMF",null,null,"Gastroenterology","Others","Others","DL-Carnitine HCl is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine.",197.66,"461-05-2",40,202.37,40,202.37,"http://selleckchem.com/products/DL-Carnitine-hydrochloride.html","C7H15NO3.HCl","Hydrochloride","N/A","[Cl-].C[N+](C)(C)CC(O)CC(O)=O",-4.49,1,1,4]
["S2295","Emodin","a3","L1300-08","in 10mM DMSO",null,"BP2018;EP9.2",null,"Others","Dehydrogenase","Metabolism","Emodin is a purgative resin, 6-methyl-1,3,8-trihydroxyanthraquinone, from rhubarb, the buckthorn and Japanese Knotweed (Fallopia japonica).",270.24,"518-82-1",54,199.82,"<1",0,"http://selleckchem.com/products/Emodin.html","C15H10O5","free base","N/A","CC1=CC2=C(C(=C1)O)C(=O)C3=C(C=C(O)C=C3O)C2=O",2.568,2,3,0]
["S2296","Enoxolone","b3","L1300-08","in 10mM DMSO","CFDA","BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia",null,"Endocrinology","Dehydrogenase","Metabolism","Enoxolone (Glycyrrhetin) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.",470.68,"471-53-4",94,199.71,"<1",0,"http://selleckchem.com/products/Enoxolone(Glycyrrhetin).html","C30H46O4","free base","Glycyrrhetin","CC1(C)C(O)CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O",5.656,2,1,1]
["S2299","Formononetin","c3","L1300-08","in 10mM DMSO",null,"BP2019",null,"Endocrinology","Others","Endocrinology & Hormones","Formononetin (Formononetol, Biochanin B) is a phytoestrogen from the root of Astragalus membranaceus and an O-methylated isoflavone.",268.26,"485-72-3",54,201.3,"<1",0,"http://selleckchem.com/products/Formononetin(Formononetol).html","C16H12O4","free base","Formononetol, Biochanin B","COC1=CC=C(C=C1)C2=COC3=C(C=CC(=C3)O)C2=O",2.608,3,1,2]
["S2300","Ferulic Acid","d3","L1300-08","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.1",null,"Cardiovascular Disease","FGFR","Angiogenesis","Ferulic Acid (Fumalic) is a hydroxycinnamic acid and a type of organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong. Ferulic acid is a novel fibroblast growth factor receptor (FGFR) inhibitor with IC50s of 3.78 μM and 12.5 μM for FGFR1 and FGFR2, respectively.",194.19,"1135-24-6",39,200.83,"<1",0,"http://selleckchem.com/products/Fumalic-acid(Ferulic-acid).html","C10H10O4","free base","Fumalic Acid","COC1=CC(=CC=C1O)\\C=C\\C(O)=O",1.669,2,1,3]
["S2302","Glycyrrhizin (NSC 167409)","e3","L1300-08","in 10mM DMSO","CFDA",null,null,"Cancer","Dehydrogenase,High-mobility Group,MAO","Metabolism","Glycyrrhizin (NSC 167409, Glycyrrhizic Acid) is a direct HMGB1(high mobility group box 1) inhibitor that inhibits HMGB1-dependent inflammatory molecule expression and oxidative stress; modulates P38 and P-JNK but not p-ERK signalling; Also inhibits 11 beta-hydroxysteroid dehydrogenase and monoamine oxidase (MAO).",822.93,"1405-86-3",100,121.52,"<1",0,"http://selleckchem.com/products/Glycyrrhizic-acid.html","C42H62O16","free base","N/A","CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O)OC6OC(C(O)C(O)C6OC7OC(C(O)C(O)C7O)C(O)=O)C(O)=O",2.417,8,5,7]
["S2303","Gossypol Acetate","f3","L1300-08","in 10mM DMSO","CFDA",null,null,"Cancer","Dehydrogenase","Metabolism","Gossypol Acetate (Gossypol Acetic acid, Pogosin, AT101) is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes.",578.61,"12542-36-8",100,172.83,"<1",0,"https://www.selleckchem.com/products/gossypol-acetate.html","C32H34O10","Acetate","Gossypol Acetic acid, Pogosin, AT101","CC(C)C1=C2C=C(C)C(=C(O)C2=C(C=O)C(=C1O)O)C3=C(O)C4=C(C=C3C)C(=C(O)C(=C4C=O)O)C(C)C.CC(O)=O",6.388,3,6,5]
["S2304","Gramine","g3","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","ADC Cytotoxin,AdipoR,Adrenergic Receptor","Metabolism","Gramine (Donaxine) is a natural indole alkaloid isolated from giant reed, acts as an active adiponectin receptor (AdipoR) agonist, with IC50 of 3.2 µM and 4.2 µM for AdipoR2 and AdipoR1, respectively. Gramine is also a human and mouse β2-Adrenergic receptor (β2-AR) agonist.",174.24,"87-52-5",35,200.87,"<1",0,"http://selleckchem.com/products/Gramine.html","C11H14N2","free base","N/A","CN(C)CC1=C[NH]C2=C1C=CC=C2",2.197,0,1,2]
["S2308","Hesperetin","h3","L1300-08","in 10mM DMSO","CFDA","EP10.4, USP43-NF38",null,"Cardiovascular Disease","Histamine Receptor,TGF-beta/Smad","TGF-beta/Smad","Hesperetin is a bioflavonoid and, to be more specific, a flavanone.",302.27,"520-33-2",60,198.5,"<1",0,"http://selleckchem.com/products/Hesperetin.html","C16H14O6","free base","N/A","COC1=CC=C(C=C1O)C2CC(=O)C3=C(O)C=C(O)C=C3O2",2.357,3,3,2]
["S2309","Hesperidin","a4","L1300-08","in 10mM DMSO","DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease/Infection","Others","Others","Hesperidin (Cirantin) is a flavanone glycoside found abundantly in citrus fruits.",610.56,"520-26-3",100,163.78,"<1",0,"http://selleckchem.com/products/Hesperidin.html","C28H34O15","free base","Cirantin","COC1=CC=C(C=C1O)C2CC(=O)C3=C(O)C=C(OC4OC(COC5OC(C)C(O)C(O)C5O)C(O)C(O)C4O)C=C3O2",-0.431,7,8,7]
["S2310","Honokiol (NSC 293100)","b4","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2",null,"Inflammation/Gastrointestinal Disease","Akt,Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,Autophagy,HCV,MEK","PI3K/Akt/mTOR","Honokiol (NSC 293100) is the active principle of magnolia extract that inhibits Akt-phosphorylation and promotes ERK1/2 phosphorylation. Honokiol causes G0/G1 phase arrest, induces apoptosis, and autophagy via the ROS/ERK1/2 signaling pathway. Honokiol inhibits hepatitis C virus (HCV) infection. Phase 3.",266.33,"35354-74-6",53,199,"<1",0,"http://selleckchem.com/products/Honokiol.html","C18H18O2","free base","N/A","OC1=C(CC=C)C=C(C=C1)C2=CC(=CC=C2O)CC=C",4.88,0,2,5]
["S2311","Hyodeoxycholic acid (HDCA)","c4","L1300-08","in 10mM DMSO","CFDA",null,null,"Cardiovascular Disease","GPCR19","GPCR & G Protein","Hyodeoxycholic (HDCA, NSC 60672) acid is a secondary bile acid, one of the metabolic byproducts of intestinal bacteria.",392.57,"83-49-8",78,198.69,"<1",0,"http://selleckchem.com/products/Hyodeoxycholic-acid(HDCA).html","C24H40O4","free base","NSC 60672","CC(CCC(O)=O)C1CCC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C",4.014,1,2,4]
["S2314","Kaempferol (NSC 407289)","d4","L1300-08","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.2",null,"Cancer/Endocrinology/Infection/Inflammation/Metabolic Disease","Estrogen/progestogen Receptor,Fatty Acid Synthase","Endocrinology & Hormones","Kaempferol (NSC 407289, Robigenin), a natural flavonol, functions as an ERRα and ERRγ inverse agonist. It inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase.",286.23,"520-18-3",57,199.14,"<1",0,"http://selleckchem.com/products/Kaempferol.html","C15H10O6","free base","Robigenin","OC1=CC=C(C=C1)C2=C(O)C(=O)C3=C(O)C=C(O)C=C3O2",1.872,2,4,1]
["S2316","Kinetin","e4","L1300-08","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Kinetin (6-Furfuryladenine) is a type of cytokinin, a class of plant hormone that promotes cell division.",215.21,"525-79-1",8,37.17,"<1",0,"http://selleckchem.com/products/Kinetin(6-Furfuryladenine).html","C10H9N5O","free base","6-Furfuryladenine","C(NC1=NC=NC2=C1[NH]C=N2)C3=CC=CO3",0.875,4,2,3]
["S2317","L-(+)-Rhamnose Monohydrate","f4","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","L(+)-Rhamnose (Rham) is a naturally-occurring deoxy sugar that is found primarily in plants and some bacteria.",182.17,"10030-85-0",36,197.62,36,197.62,"http://selleckchem.com/products/l-positive-rotation-rhamnose-monohydrate.html","C6H12O5.H2O","Monohydrate","N/A","O.CC1OC(O)C(O)C(O)C1O",-1.833,1,3,0]
["S2318","Lappaconitine","g4","L1300-08","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Inflammation/Neurological Disease","Sodium Channel","Transmembrane Transporters","Lappaconitine (LC) is a natural diterpenoid alkaloid (DTA), acting as a human heart sodium channel blocker and possessing a wide range of biological activities, including anti-arrhythmic, anti-inflammatory, antioxidative, anticancer, epileptiform etc.",584.7,"32854-75-4",16,27.36,0,0,"http://selleckchem.com/products/lappaconitine.html","C32H44N2O8","free base","N/A","CCN1CC2(CCC(OC)C34C2CC(C13)C5(O)CC(OC)C6CC4C5(O)C6OC)OC(=O)C7=CC=CC=C7NC(C)=O",0.029,6,1,8]
["S2320","Luteolin","h4","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2",null,"Angiology/Cancer/Infection/Inflammation","ADC Cytotoxin,PDE","Metabolism","Luteolin (Luteoline, Luteolol, Digitoflavone) is a flavonoid found in Terminalia chebula, which is a non-selective phisphodiesterase PDE inhibitor for PDE1-5 with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM, respectively.",286.24,"491-70-3",57,199.13,"<1",0,"https://www.selleckchem.com/products/luteolin.html","C15H10O6","free base","Luteoline, Luteolol, Digitoflavone","OC1=CC(=C2C(=O)C=C(OC2=C1)C3=CC=C(O)C(=C3)O)O",2.168,2,4,1]
["S2321","Magnolol","a5","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Fungal,NF-κB","NF-κB","Magnolol (NSC 293099) is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. It can block TNF-α-induced NF-KB activation.",266.33,"528-43-8",53,199,"<1",0,"http://selleckchem.com/products/Magnolol(2,2-Bichavicol).html","C18H18O2","free base","NSC 293099","OC1=C(C=C(CC=C)C=C1)C2=CC(=CC=C2O)CC=C",4.88,0,2,5]
["S2322","(+)-Matrine","b5","L1300-08","in 10mM DMSO","CFDA",null,null,"Cancer","Opioid Receptor","Neuronal Signaling","Matrine((+)-Matrine) is an alkaloid found in plants from the Sophora family, which has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist.",248.36,"519-02-8",49,197.29,11,44.29,"http://selleckchem.com/products/matrine.html","C15H24N2O","free base","N/A","O=C1CCCC2C3CCCN4CCCC(CN12)C34",1.417,1,0,0]
["S2325","Morin Hydrate","c5","L1300-08","in 10mM DMSO",null,"USP42-NF37",null,"Cancer/Immunology","Others","Others","Morin hydrate (Aurantica) is a flavonoid isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava).",320.25,"6202-27-3",64,199.84,"<1",0,"https://www.selleckchem.com/products/Morin-hydrate.html","C15H10O7.H2O","Hydrate","Aurantica","O.OC1=CC=C(C(=C1)O)C2=C(O)C(=O)C3=C(O)C=C(O)C=C3O2",1.423,2,5,1]
["S2328","Nalidixic acid","d5","L1300-08","in 10mM DMSO","FDA,DMF,CFDA,PMDA","USP42-NF37;BP2019;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","070270,070271,070272,071919,071936,072061","Infection","Selection Antibiotics for Transfected Cell,Topoisomerase","DNA Damage/DNA Repair","Nalidixic acid (NSC-82174) is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.",232.24,"389-08-2",6,25.84,"<1",0,"http://selleckchem.com/products/Nalidixic-acid(NegGram).html","C12H12N2O3","free base","NSC-82174","CCN1C=C(C(O)=O)C(=O)C2=C1N=C(C)C=C2",1.176,3,0,2]
["S2329","Naringin","e5","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Infection/Inflammation/Neurological Disease","P450 (e.g. CYP17)","Metabolism","Naringin (Naringoside) is a flavanone glycoside, which exerts a variety of pharmacological effects such as antioxidant activity, blood lipid lowering, anticancer activity, and inhibition of cytochrome P450 enzymes.",580.53,"10236-47-2",100,172.26,"<1",0,"http://selleckchem.com/products/Naringin(Naringoside).html","C27H32O14","free base","Naringoside","CC1OC(OC2C(O)C(O)C(CO)OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC=C(O)C=C5)O)C(O)C(O)C1O",-0.415,6,8,6]
["S2331","Neohesperidin Dihydrochalcone (Nhdc)","f5","L1300-08","in 10mM DMSO",null,"EP9.1;BP2017",null,"Cancer/Cardiovascular Disease/Endocrinology/Metabolic Disease","Others","Others","Neohesperidin dihydrochalcone(Nhdc, NCI-c60764), sometimes abbreviated to neohesperidin DC or simply NHDC, is an artificial sweetener derived from citrus.",612.58,"20702-77-6",100,163.24,"<1",0,"http://selleckchem.com/products/Neohesperidin-dihydrochalcone(Nhdc).html","C28H36O15","free base","NCI-c60764","COC1=C(O)C=C(CCC(=O)C2=C(O)C=C(OC3OC(CO)C(O)C(O)C3OC4OC(C)C(O)C(O)C4O)C=C2O)C=C1",-0.048,6,9,10]
["S2332","Neohesperidin","g5","L1300-08","in 10mM DMSO",null,"EP9.1;BP2017",null,"Cancer/Cardiovascular Disease/Endocrinology/Metabolic Disease","ROS","Immunology & Inflammation","Neohesperidin (NSC 31048), a flavanone glycoside found in citrus fruits, is an antioxidant agent., Neohesperidin (NSC 31048) 是一种抗氧化剂，在1,1-diphenyl-2-picryldydrazyl（DPPH）自由基清除测定中，IC50为22.31 μg/ml。",610.56,"13241-33-3",122,199.82,"<1",0,"http://selleckchem.com/products/Neohesperidin.html","C28H34O15","free base","NSC 31048","COC1=CC(=CC(=C1)C2CC(=O)C3=C(O)C=C(OC4OC(CO)C(O)C(O)C4OC5OC(C)C(O)C(O)C5O)C=C3O2)O",-0.431,7,8,7]
["S2334","Oleanolic Acid","h5","L1300-08","in 10mM DMSO","CFDA","BP2019;EP9.2",null,"Infection","Antiviral","Microbiology","Oleanolic Acid (Caryophyllin) is a non-toxic, hepatoprotective triterpenoid found in Phytolacca Americana, which exerts antitumor and antiviral properties.",456.7,"508-02-1",21,45.98,"<1",0,"http://selleckchem.com/products/Oleanolic-Acid(Caryophyllin).html","C30H48O3","free base","Caryophyllin","CC1(C)CC(C2CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC34C)C2C1)C(O)=O",6.282,1,1,1]
["S2336","Orotic acid (6-Carboxyuracil)","a6","L1300-08","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease/Endocrinology","Others","Others","Orotic acid(6-Carboxyuracil) is a heterocyclic compound and an acid.",156.1,"65-86-1",2,12.81,"<1",0,"http://selleckchem.com/products/Orotic-acid(6-Carboxyuracil).html","C5H4N2O4","free base","N/A","OC(=O)C1=CC(=O)NC(=O)N1",-1.152,3,2,1]
["S2337","Osthole","b6","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cardiovascular Disease","Others","Others","Osthol is an O-methylated coumarin, which is found in the plants such as Cnidium monnieri, Angelica archangelica and Angelica pubescens.",244.29,"484-12-8",49,200.58,"<1",0,"http://selleckchem.com/products/Osthole(Osthol).html","C15H16O3","free base","Osthol","COC1=CC=C2C=CC(=O)OC2=C1CC=C(C)C",3.74,3,0,3]
["S2338","Oxymatrine","c6","L1300-08","in 10mM DMSO","CFDA","CP2005",null,"Infection","Immunology & Inflammation related","TGF-beta/Smad","Oxymatrine (Matrine N-oxide) is a quinolizidine alkaloid extracted from the root of Sophora flavescens with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. It is used for the treatment of viral hepatitis, cancer, viral myocarditis, gastrointestinal hemorrhage and skin diseases.",264.36,"16837-52-8",53,200.48,53,200.48,"http://selleckchem.com/products/Oxymatrine(Matrine-N-oxide).html","C15H24N2O2","free base","Matrine N-oxide","[O-][N+]12CCCC3CN4C(CCCC4=O)C(CCC1)C23",0.61,1,0,0]
["S2339","Paeonol","d6","L1300-08","in 10mM DMSO","CFDA","BP2019;EP9.2;CP2005",null,"Immunology/Inflammation","MAO","Metabolism","Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 μM.",166.17,"552-41-0",33,198.59,"<1",0,"http://selleckchem.com/products/Paeonol(Peonol).html","C9H10O3","free base","Peonol","COC1=CC(=C(C=C1)C(C)=O)O",1.311,2,1,2]
["S2341","(-)-Parthenolide","e6","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2",null,"Immunology/Inflammation","HDAC,MDM2/MDMX,NF-κB,p53","NF-κB","(-)-Parthenolide, an inhibitor of the Nuclear Factor-κB Pathway, specifically depletes HDAC1 protein without affecting other class I/II HDACs; Also promotes the ubiquitination of MDM2 and activates p53 cellular functions.",248.32,"20554-84-1",49,197.33,"<1",0,"http://selleckchem.com/products/Parthenolide((-)-Parthenolide).html","C15H20O3","free base","N/A","CC/1=C\\CCC2(C)OC2C3OC(=O)C(=C)C3CC1",2.923,3,0,0]
["S2344","Piperine","f6","L1300-08","in 10mM DMSO","NDC","BP2019;EP9.2",null,"Neurological Disease","P450 (e.g. CYP17)","Metabolism","Piperine (1-Piperoylpiperidine) is the alkaloid responsible for the pungency of black pepper and long pepper, which has also been used in some forms of traditional medicine and as an insecticide.",285.34,"94-62-2",57,199.76,"<1",0,"http://selleckchem.com/products/Piperine(1-Piperoylpiperidine).html","C17H19NO3","free base","1-Piperoylpiperidine","O=C(\\C=C\\C=C\\C1=CC2=C(OCO2)C=C1)N3CCCCC3",2.864,3,0,3]
["S2346","Puerarin","g6","L1300-08","in 10mM DMSO","CFDA","BP2019;EP9.2;CP2005",null,"Psychotic disorders","5-HT Receptor","Neuronal Signaling","Puerarin (Kakonein), an isoflavones found in the root of Radix puerariae, is a 5-HT2C receptor and benzodiazepine site antagonist.",416.38,"3681-99-0",86,206.54,"<1",0,"http://selleckchem.com/products/Puerarin(Kakonein).html","C21H20O9","free base","Kakonein","OCC1OC(OC2=C(O)C=CC3=C2OC=C(C3=O)C4=CC=C(O)C=C4)C(O)C(O)C1O",0.21,4,6,4]
["S2347","Quercetin Dihydrate","h6","L1300-08","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Cancer/Cardiovascular Disease/Endocrinology/Metabolic Disease/Inflammation","PI3K,Sirtuin","PI3K/Akt/mTOR","Quercetin (Sophoretin), a polyphenolic flavonoid found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine, is utilized in many different cultures for their nervous system and anticancer effects. Quercetin (dihydrate), a natural flavonoid, is a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC50s of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively.",338.27,"6151-25-3",67,198.07,"<1",0,"http://selleckchem.com/products/Quercetin-dihydrate(Sophoretin).html","C15H10O7.2H2O","Dihydrate","Sophoretin","O.O.OC1=CC(=C2C(=O)C(=C(OC2=C1)C3=CC=C(O)C(=C3)O)O)O",1.216,2,5,1]
["S2348","Rotenone (Barbasco)","a7","L1300-08","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","Apoptosis related,Mitochondrial Metabolism,Mitophagy,NADPH-oxidase,ROS","Immunology & Inflammation","Rotenone (Barbasco, Dactinol, Paraderil, Rotenon, Rotocide) is a botanical insecticide that is an inhibitor of mitochondrial electron transport. Rotenone inhibits NADH/DB oxidoreductase and NADH oxidase with IC50 of 28.8 nM and 5.1 nM, respectively. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production.",394.42,"83-79-4",78,197.76,0,0,"http://selleckchem.com/products/rotenone-barbasco.html","C23H22O6","free base","Barbasco, Dactinol, Paraderil, Rotenon, Rotocide","COC1=CC2=C(C=C1OC)C3C(CO2)OC4=C(C=CC5=C4CC(O5)C(C)=C)C3=O",3.93,6,0,3]
["S2349","Rutaecarpine","b7","L1300-08","in 10mM DMSO",null,"EP10.4",null,"Inflammation","COX","Neuronal Signaling","Rutaecarpine (Rutecarpine) is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs; a new class of COX-2 inhibitor.",287.32,"84-26-4",24,83.53,"<1",0,"http://selleckchem.com/products/Rutaecarpine(Rutecarpine).html","C18H13N3O","free base","Rutecarpine","O=C1N2CCC3=C([NH]C4=C3C=CC=C4)C2=NC5=C1C=CC=C5",3.359,2,1,0]
["S2350","Rutin","c7","L1300-08","in 10mM DMSO","DMF,CFDA,NDC","USP42-NF37;EP8.8;CP2005",null,"Endocrinology/Hematology","ADC Cytotoxin,Immunology & Inflammation related","Immunology & Inflammation","Rutin (Rutoside), a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human.",610.52,"153-18-4",100,163.79,"<1",0,"http://selleckchem.com/products/Rutin(Rutoside).html","C27H30O16","free base","Rutoside","CC1OC(OCC2OC(OC3=C(OC4=C(C(=CC(=C4)O)O)C3=O)C5=CC(=C(O)C=C5)O)C(O)C(O)C2O)C(O)C(O)C1O",-1.158,6,10,6]
["S2351","Salicin","d7","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2",null,"Inflammation","COX","Neuronal Signaling","Salicin (Salicoside, Salicine) is a phenol β-glycosid produced from willow bark that shows anti-inflammatory effects. It is a natural, non-selective COX-1 and COX-2 inhibitor.",286.28,"138-52-3",57,199.11,24,83.83,"http://selleckchem.com/products/Salicin(Salicoside,-Salicine).html","C13H18O7","free base","Salicoside,Salicine","OCC1OC(OC2=CC=CC=C2CO)C(O)C(O)C1O",-0.947,2,5,4]
["S2354","Sclareol","e7","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cancer/Hematology","Others","Others","Sclareol, a labdane-type diterpene isolated from clary sage (Salvia sclarea), exerts growth inhibition and cytotoxic activity against a variety of human cancer cell lines.",308.5,"515-03-7",61,197.73,"<1",0,"http://selleckchem.com/products/Sclareol.html","C20H36O2","free base","N/A","CC1(C)CCCC2(C)C1CCC(C)(O)C2CCC(C)(O)C=C",4.27,0,0,4]
["S2357","Silibinin (NSC 651520)","f7","L1300-08","in 10mM DMSO","CFDA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Inflammation","Others","Others","Silibinin (NSC 651520, Silybin, Silibinin A, Silymarin I, Flavobin), the main flavonoid extracted from the milk thistle Silybum marianum, displays hepatoprotective properties in acute and chronic liver injury.",482.44,"22888-70-6",96,198.99,"<1",0,"http://selleckchem.com/products/Silibinin(Silybin).html","C25H22O10","free base","Silybin, Silibinin A, Silymarin I, Flavobin","COC1=CC(=CC=C1O)C2OC3=CC(=CC=C3OC2CO)C4OC5=CC(=CC(=C5C(=O)C4O)O)O",2.592,5,5,4]
["S2358","Silymarin","g7","L1300-08","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Inflammation","Antioxidant","Angiogenesis","Silymarin (Silybin B), a polyphenolic flavonoid extracted from the seeds of Silybum marianum or milk thistle, is used in the prevention and treatment of liver diseases and primary liver cancer.",482.44,"65666-07-1",96,198.99,"<1",0,"http://selleckchem.com/products/Silymarin(Silybin-B).html","C25H22O10","free base","Silybin B","COC1=CC(=CC=C1O)C2OC3=CC=C(C=C3OC2CO)C4OC5=C(C(=CC(=C5)O)O)C(=O)C4O",2.592,5,5,4]
["S2359","Sinomenine","h7","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2;CP2005",null,"Infection/Inflammation/Neurological Disease/Respiratory Disease","Immunology & Inflammation related","Immunology & Inflammation","Sinomenine (Cucoline, Kukoline), a pure alkaloid extracted from the chinese medical plant Sinomenium acutum, is used for the treatment of rheumatism and arthritis.",329.39,"115-53-7",65,197.33,65,197.33,"http://selleckchem.com/products/Sinomenine(Cucoline).html","C19H23NO4","free base","Cucoline, Kukoline","COC1=CC2C3CC4=C(C(=C(OC)C=C4)O)C2(CCN3C)CC1=O",1.674,3,1,2]
["S2362","Synephrine","a8","L1300-08","in 10mM DMSO","NDC",null,null,"Neurological Disease","Adrenergic Receptor","GPCR & G Protein","Synephrine (Oxedrine), a natural protoalkaloid in the extract of bitter orange and other citrus species, is commonly used for weight loss.",167.21,"94-07-5",33,197.36,"<1",0,"http://selleckchem.com/products/Synephrine(Oxedrine).html","C9H13NO2","free base","Oxedrine","CNCC(O)C1=CC=C(O)C=C1",0.615,0,3,3]
["S2364","Tanshinone I","b8","L1300-08","in 10mM DMSO","CFDA",null,null,"Cancer/Inflammation","Phospholipase (e.g. PLA)","Metabolism","Tanshinone I, an active principle isolated from Salvia miltiorrhiza (Danshen), is structurally similar to tanshinone IIA and may possess similar cytotoxic effects on tumor cells.",276.29,"568-73-0",23,83.25,"<1",0,"http://selleckchem.com/products/Tanshinone-I.html","C18H12O3","free base","N/A","CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C(C)C=CC=C34",4.084,3,0,0]
["S2365","Tanshinone IIA","c8","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cardiovascular Disease","Lipase","Metabolism","Tanshinone IIA (Tanshinone B) is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae Radix, a widely prescribed traditional herbal medicine that is used to treat cardiovascular and inflammatory diseases; A natural monoacylglycerol lipase inhibitor.",294.34,"568-72-9",5,16.99,"<1",0,"http://selleckchem.com/products/Tanshinone-IIA(Tanshinone-B).html","C19H18O3","free base","Tanshinone B","CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C",4.66,3,0,0]
["S2366","Taxifolin (Dihydroquercetin)","d8","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cardiovascular Disease","VEGFR","Angiogenesis","Taxifolin, type I inhibitor for VEGFR-2 kinase, is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.",304.25,"480-18-2",60,197.21,"<1",0,"http://selleckchem.com/products/Taxifolin(Dihydroquercetin).html","C15H12O7","free base","N/A","OC1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(O)C=C3)O",1.479,2,5,1]
["S2369","Troxerutin","e8","L1300-08","in 10mM DMSO","DMF,CFDA,NDC","EP9.3;BP2019;Martindale:The Extra Pharmacopoeia",null,"Angiology/Cardiovascular Disease","NLR,ROS","Immunology & Inflammation","Troxerutin, a natural bioflavonoid isolated from Sophora japonica, has been reported to have many benefits and medicinal properties. Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation.",742.68,"7085-55-4",100,134.65,100,134.65,"http://selleckchem.com/products/Troxerutin.html","C33H42O19","free base","N/A","CC1OC(OCC2OC(OC3=C(OC4=CC(=CC(=C4C3=O)O)OCCO)C5=CC(=C(OCCO)C=C5)OCCO)C(O)C(O)C2O)C(O)C(O)C1O",-2.1,9,10,15]
["S2370","Ursolic Acid","f8","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2;CP2005",null,"Cardiovascular Disease","Others","Others","Ursolic acid (NSC 167406, NSC-4060, Prunol, Urson, Malol) is a pentacyclic triterpene acid, used in cosmetics.",456.7,"77-52-1",91,199.26,"<1",0,"http://selleckchem.com/products/Ursolic-acid(Malol).html","C30H48O3","free base","NSC 167406, NSC-4060, Prunol, Urson, Malol","CC1CC(C2CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC34C)C2C1C)C(O)=O",6.327,1,1,1]
["S2373","Yohimbine HCl","g8","L1300-08","in 10mM DMSO","DMF","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Adrenergic Receptor","Neuronal Signaling","Yohimbine (Antagonil) has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.",390.9,"65-19-0",12,30.7,"<1",0,"http://selleckchem.com/products/Yohimbine-hydrochloride(Antagonil).html","C21H26N2O3.HCl","Hydrochloride","Antagonil","Cl.COC(=O)C1C(O)CCC2CN3CCC4=C([NH]C5=C4C=CC=C5)C3CC12",3.204,2,2,2]
["S2374","5-hydroxytryptophan (5-HTP)","h8","L1300-08","in 10mM DMSO","DMF,NDC",null,null,"Psychotic disorders","Others","Others","5-Hydroxytryptophan (5-HTP, NSC-92523), also known as oxitriptan (INN), is a naturally occurring amino acid and chemical precursor for the treatment of depression.",220.22,"56-69-9",44,199.8,4,18.16,"http://selleckchem.com/products/5-hydroxytryptophan(5-HTP).html","C11H12N2O3","free base","NSC-92523","NC(CC1=C[NH]C2=CC=C(O)C=C12)C(O)=O",-1.554,1,3,3]
["S2375","Aloin","a9","L1300-08","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia;CP2005",null,"Gastroenterology","Tyrosinase","Proteases","Aloin (Barbaloin, Barbalin), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.",418.39,"1415-73-2",83,198.38,83,198.38,"http://selleckchem.com/products/Aloin(Barbaloin).html","C21H22O9","free base","Barbaloin, Barbalin","OCC1OC(C(O)C(O)C1O)C2C3=C(C(=CC=C3)O)C(=O)C4=C2C=C(CO)C=C4O",-0.404,2,7,3]
["S2376","Ammonium Glycyrrhizinate","b9","L1300-08","in 10mM DMSO","CFDA",null,null,"Respiratory Disease","Dehydrogenase,High-mobility Group","Metabolism","Ammonium Glycyrrhizinate (AMGZ, Glycyram, Glycyrrhizin ammonium salt, Glycyrrhizic acid ammonium salt) is a unique product from Licorice root with a very high sweetness. Ammonium glycyrrhizinate is a direct inhibitor of HMGB1 with anti-inflammatory, anti-tumor, anti-diabetic activities. Ammonium Glycyrrhizinate inhibits growth and cytopathology of several unrelated DNA and RNA viruses. Ammonium Glycyrrhizinate also inhibits both hepatic delta 4-5-reductase and 11 beta-hydroxysteroid dehydrogenase.",839.96,"1407-03-0",168,200.01,5,5.95,"http://selleckchem.com/products/Ammonium-Glycyrrhizinate(AMGZ).html","C42H62O16.NH3","Glycyrrhizic acid salt","AMGZ, Glycyram, Glycyrrhizin ammonium salt, Glycyrrhizic acid ammonium salt","N.CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O)OC6OC(C(O)C(O)C6OC7OC(C(O)C(O)C7O)C(O)=O)C(O)=O",-0.915,8,5,7]
["S2378","Butylscopolamine Bromide","c9","L1300-08","in 10mM DMSO","CFDA",null,null,"Neurological Disease","AChR","Neuronal Signaling","Butylscopolamine Bromide (Scopolamine Butylbromide,(-)-Scopolamine butylbromide, Hyoscine butylbromide), is a peripherally acting antimuscarinic, anticholinergic agent used as an abdominal-specific antispasmodic.",440.37,"149-64-4",88,199.83,88,199.83,"http://selleckchem.com/products/butylscopolamine-bromide.html","C21H30NO4.Br","Bromide","Scopolamine Butylbromide,(-)-Scopolamine butylbromide, Hyoscine butylbromide","[Br-].CCCC[N+]1(C)C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",-1.62,3,1,8]
["S2379","Dioscin","d9","L1300-08","in 10mM DMSO","CFDA",null,null,"Cancer","Others","Others","Dioscin (Collettiside III, Saponin) is a saponin extracted and isolated from Polygonatum Zanlanscianense Pamp, showing antitumor activities.",869.04,"19057-60-4",100,115.07,"<1",0,"http://selleckchem.com/products/Dioscin(Collettiside-III).html","C45H72O16","free base","Collettiside III, Saponin","CC1CCC2(OC1)OC3CC4C5CC=C6CC(CCC6(C)C5CCC4(C)C3C2C)OC7OC(CO)C(OC8OC(C)C(O)C(O)C8O)C(O)C7OC9OC(C)C(O)C(O)C9O",1.169,8,8,7]
["S2380","Diosmetin","e9","L1300-08","in 10mM DMSO","NDC",null,null,"Immunology/Infection","P450 (e.g. CYP17)","Metabolism","Diosmetin (Luteolin 4-methyl ether) is a bioflavonoid found in spearmint, oregano, and many other plants.",300.26,"520-34-3",60,199.83,"<1",0,"http://selleckchem.com/products/Diosmetin(Luteolin-4-methyl-ether).html","C16H12O6","free base","Luteolin 4-methyl ether","COC1=CC=C(C=C1O)C2=CC(=O)C3=C(O)C=C(O)C=C3O2",2.394,3,3,2]
["S2381","D-Mannitol","f9","L1300-08","in 10mM DMSO","DMF","USP42-NF37;JP17;BP2018;IP2010",null,"Metabolic Disease","Others","Others","D-Mannitol is an osmotic diuretic agent and a weak renal vasodilator.",182.17,"69-65-8",36,197.62,36,197.62,"http://selleckchem.com/products/D-Mannitol(Osmitrol).html","C6H14O6","free base","Osmitrol","OCC(O)C(O)C(O)C(O)CO",-2.941,0,6,5]
["S2382","Evodiamine","g9","L1300-08","in 10mM DMSO",null,"EP9.2",null,"Cancer/Inflammation","NF-κB","NF-κB","Evodiamine (Isoevodiamine), an alkaloid extract from the fruit of Evodiae Fructus exhibits antitumor activities against the human tumor cells. It is shown to inhibit NF-kB activation through suppression of IkB kinase activity.",303.36,"518-17-2",12,39.56,"<1",0,"http://www.selleck.cn/products/Evodiamine(Isoevodiamine).html","C19H17N3O","Free Base","Isoevodiamine","CN1C2N(CCC3=C2[NH]C4=CC=CC=C34)C(=O)C5=C1C=CC=C5",3.673,1,1,0]
["S2383","Gastrodin","h9","L1300-08","in 10mM DMSO","CFDA","CP2005",null,"Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Gastrodin (Gastrodine), an anti-inflammatory polyphenol extracted from Chinese natural herbal Gastrodia elata Blume., benefits neurodegenerative diseases.",286.28,"62499-27-8",50,174.65,"<1",0,"http://selleckchem.com/products/Gastrodin(Gastrodine).html","C13H18O7","free base","Gastrodine","OCC1OC(OC2=CC=C(CO)C=C2)C(O)C(O)C1O",-0.947,2,5,4]
["S2384","Hematoxylin","a10","L1300-08","in 10mM DMSO",null,"USP42-NF37;IP2010",null,"Others","Dyes","Others","Hematoxylin (Hydroxybrazilin) is a compound that forms strongly colored complexes with certain metal ions, notably Fe(III) and Al(III) salts and a kind of stain in histology.",302.28,"517-28-2",61,201.8,61,201.8,"http://selleckchem.com/products/Hematoxylin(Hydroxybrazilin).html","C16H14O6","free base","Hydroxybrazilin","OC1=CC2=C(C=C1O)C3C4=C(OCC3(O)C2)C(=C(O)C=C4)O",1.691,1,4,0]
["S2386","Indirubin (NSC 105327)","b10","L1300-08","in 10mM DMSO","CFDA","BP2019;EP9.2;CP2005",null,"Cancer/Hematology","GSK-3","PI3K/Akt/mTOR","Indirubin (NSC 105327) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 μM and 0.6 μM.",262.26,"479-41-4",53,202.09,"<1",0,"http://selleckchem.com/products/Indirubin.html","C16H10N2O2","free base","NSC 105327","O=C1NC2=CC=CC=C2\\C1=C3/NC4=C(C=CC=C4)C3=O",1.876,2,2,0]
["S2387","Lappaconite HBr","c10","L1300-08","in 10mM DMSO","CFDA",null,null,"Cardiovascular Disease","ADC Cytotoxin,Immunology & Inflammation related","Immunology & Inflammation","Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects.",665.61,"97792-45-5",28,42.07,"<1",0,"http://selleckchem.com/products/Lappaconite-Hydrobromide.html","C32H44N2O8.HBr","Hydrobromide","N/A","Br.CCN1CC2(CCC(OC)C34C2CC(C13)C5(O)CC(OC)C6CC4C5(O)C6OC)OC(=O)C7=C(NC(C)=O)C=CC=C7",0.52,6,1,8]
["S2388","L-carnitine","d10","L1300-08","in 10mM DMSO","DMF,NDC",null,null,"Metabolic Disease","Others","Others","L-carnitine (Levocarnitine,Carnitor, vitamin BT, Karnitin,L(-)-Carnitine) is constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.",161.2,"541-15-1",12,74.44,32,198.51,"http://selleckchem.com/products/L-carnitine(Levocarnitine).html","C7H15NO3","quaternary-N  salt","Levocarnitine,Carnitor, vitamin BT, Karnitin,L(-)-Carnitine","C[N+](C)(C)CC(O)CC([O-])=O",-3.29,0,1,4]
["S2389","Naringin Dihydrochalcone","e10","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2;CP2005;Martindale:The Extra Pharmacopoeia",null,"Metabolic Disease","P450 (e.g. CYP17)","Metabolism","Naringin Dihydrochalcone(Naringin DC) is a new-style sweetening agent and an artificial sweetener derived from naringin and also an inhibitor of CYP enzymes.",582.55,"18916-17-1",100,171.66,"<1",0,"http://selleckchem.com/products/Naringin-Dihydrochalcone(Naringin-DC).html","C27H34O14","free base","N/A","CC1OC(OC2C(O)C(O)C(CO)OC2OC3=CC(=C(C(=O)CCC4=CC=C(O)C=C4)C(=C3)O)O)C(O)C(O)C1O",-0.032,5,9,9]
["S2390","Polydatin","f10","L1300-08","in 10mM DMSO","NDC","BP2019;EP9.2;CP2005",null,"Cardiovascular Disease/Infection/Respiratory Disease","Phospholipase (e.g. PLA)","Metabolism","Polydatin (Piceid) is a crystal component extracted from the root stem of perennial herbage Polygonum Cuspidatum Sieb.et Zucc.",390.38,"65914-17-2",78,199.81,"<1",0,"http://selleckchem.com/products/Polydatin(Piceid).html","C20H22O8","free base","Piceid","OCC1OC(OC2=CC(=CC(=C2)\\C=C\\C3=CC=C(O)C=C3)O)C(O)C(O)C1O",1.16,2,6,5]
["S2391","Quercetin (NSC 9221)","g10","L1300-08","in 10mM DMSO","DMF,NDC","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Cancer/Cardiovascular Disease/Endocrinology/Metabolic Disease/Inflammation","Apoptosis related,Autophagy,Mitophagy,PI3K,PKC,Sirtuin,Src","Epigenetics","Quercetin (NSC 9221, Sophoretin, C.I. 75720), a natural flavonoid present in vegetables, fruit and wine, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4-5.4 μM. Quercetin induces mitophagy, apoptosis and protective autophagy. Phase 4.",302.24,"117-39-5",61,201.83,"<1",0,"http://selleckchem.com/products/Quercetin(Sophoretin).html","C15H10O7","Free Base","Sophoretin, C.I. 75720","OC1=CC(=C2C(=O)C(=C(OC2=C1)C3=CC=C(O)C(=C3)O)O)O",1.63,2,5,1]
["S2393","Sorbitol","h10","L1300-08","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;EP9.8;BP2019;JP17;IP2010;Martindale:The Extra Pharmacopoeia","080224","Others","Others","Others","Sorbitol (Glucitol) is a sugar alcohol and a sugar substitute.",182.17,"50-70-4",36,197.62,36,197.62,"http://selleckchem.com/products/Sorbitol(Glucitol).html","C6H14O6","free base","Glucitol","OCC(O)C(O)C(O)C(O)CO",-2.941,0,6,5]
["S2396","Salidroside","a11","L1300-08","in 10mM DMSO",null,"CP2005",null,"Cancer","Mitophagy,mTOR,PREP","PI3K/Akt/mTOR","Salidroside (Rhodioloside), a phenylpropanoid glycoside isolated from Rhodiola rosea, has been reported to have a broad spectrum of pharmacological properties. Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.",300.3,"10338-51-9",60,199.8,60,199.8,"http://selleckchem.com/products/Salidroside-Rhodioloside.html","C14H20O7","free base","Rhodioloside","OCC1OC(OCCC2=CC=C(O)C=C2)C(O)C(O)C1O",-0.443,2,5,5]
["S2397","Palmatine chloride","b11","L1300-08","in 10mM DMSO",null,"BP2019",null,"Infection/Ophthalmology","Calcium Channel","Neuronal Signaling","Palmatine hydrochloride (Palmatine chloride (6CI,7CI); Fibrauretin) is a hydrochloride salt of palmatine which is a protoberberine alkaloid.",387.86,"10605-02-4",77,198.53,5,12.89,"http://selleckchem.com/products/Palmatine-chloride.html","C21H22NO4.Cl","Chloride","N/A","[Cl-].COC1=CC=C2C=C3C4=C(CC[N+]3=CC2=C1OC)C=C(OC)C(=C4)OC",1.488,4,0,4]
["S2401","Sodium Danshensu","c11","L1300-08","in 10mM DMSO",null,"CP2005",null,"Cardiovascular Disease","P450 (e.g. CYP17)","Metabolism","Sodium Danshensu is a mono sodium of danshensu, which is a natural phenolic acid of caffeic acid derivatives isolated from Salvia miltiorrhiza.",220.15,"67920-52-9",7,31.8,2,9.08,"http://selleckchem.com/products/Sodium-Danshensu.html","C9H9O5.Na","Sodium Salt","N/A","[Na+].OC(CC1=CC(=C(O)C=C1)O)C([O-])=O",-0.795,0,3,3]
["S2403","Tetrandrine (NSC-77037)","d11","L1300-08","in 10mM DMSO","CFDA","EP8.8,BP2017",null,"Others","Calcium Channel","Transmembrane Transporters","Tetrandrine (NSC-77037, Fanchinine, d-Tetrandrine), a bis-benzylisoquinoline alkaloid derived from Stephania tetrandra, is a calcium channel blocker.",622.75,"518-34-3",7,11.24,"<1",0,"http://www.selleck.cn/products/Tetrandrine-Fanchinine.html","C38H42N2O6","Free Base","Fanchinine, d-Tetrandrine","COC1=CC=C2CC3N(C)CCC4=CC(=C(OC)C(=C34)OC5=C(OC)C=C6CCN(C)C(CC7=CC=C(OC1=C2)C=C7)C6=C5)OC",7.218,6,0,4]
["S2410","Paeoniflorin (NSC 178886)","f11","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cardiovascular Disease/Respiratory Disease","COX,HIF","Immunology & Inflammation","Paeoniflorin (NSC 178886,Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin reduces COX-2 expression. Paeoniflorin alleviates liver fibrosis by inhibiting HIF-1α through mTOR-dependent pathway.",480.46,"23180-57-6",96,199.81,96,199.81,"http://selleckchem.com/products/paeoniflorin.html","C23H28O11","free base","NSC 178886,Peoniflorin","CC12CC3(O)OC(O1)C4(COC(=O)C5=CC=CC=C5)C3CC24OC6OC(CO)C(O)C(O)C6O",-1.283,6,4,7]
["S2411","Geniposide","g11","L1300-08","in 10mM DMSO",null,"BP2019;EP9.2;CP2005",null,"Cardiovascular Disease/Endocrinology/Metabolic Disease","Immunology & Inflammation related","Immunology & Inflammation","Geniposide is an iridoid glycoside isolated from the fruit of Gardenia jasminoides Ellis.",388.37,"24512-63-8",78,200.84,78,200.84,"http://selleckchem.com/products/geniposide.html","C17H24O10","free base","N/A","COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C3C1CC=C3CO",-2.066,5,5,6]
["S2422","Ipriflavone (Osteofix)","h11","L1300-08","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Ipriflavone (7-Isopropoxyisoflavon) is used to inhibit bone resorption.",280.32,"35212-22-7",56,199.77,"<1",0,"http://selleckchem.com/products/ipriflavone.html","C18H16O3","free base","N/A","CC(C)OC1=CC=C2C(=C1)OC=C(C2=O)C3=CC=CC=C3",3.576,3,0,3]
["S2423","(S)-10-Hydroxycamptothecin","a2","L1300-09","in 10mM DMSO","DMF",null,null,"Cancer","Topoisomerase","DNA Damage/DNA Repair","(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor with potent anti-tumor activity.",364.35,"19685-09-7",8,21.96,"<1",0,"http://selleckchem.com/products/10-hydroxycamptothecin.html","C20H16N2O5","free base","10-HCPT","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=CC5=CC(=CC=C5N=C34)O)C2=O",1.504,4,1,1]
["S2437","Rotundine","b2","L1300-09","in 10mM DMSO","CFDA",null,null,"Neurological Disease","Dopamine Receptor","Neuronal Signaling","Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.",355.43,"483-14-7",8,22.51,"<1",0,"http://selleckchem.com/products/rotundine.html","C21H25NO4","free base","L-tetrahydropalmatine, L-THP","COC1=CC2=C(C=C1OC)C3CC4=CC=C(OC)C(=C4CN3CC2)OC",3.599,4,0,4]
["S2438","Synephrine HCl","c2","L1300-09","in 10mM DMSO","NDC",null,null,"Neurological Disease","Adrenergic Receptor","Neuronal Signaling","SynephrineHCl (Oxedrine, p-Synephrine) is a sympathomimetic α-adrenergic receptor (AR) agonist.",203.67,"5985-28-4",14,68.74,41,201.31,"http://selleckchem.com/products/synephrine-hcl.html","C9H13NO2.HCl","Hydrochloride","N/A","Cl.CNCC(O)C1=CC=C(O)C=C1",0.997,0,3,3]
["S2439","Guanosine","d2","L1300-09","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond.",283.24,"118-00-3",56,197.71,"<1",0,"http://selleckchem.com/products/guanosine.html","C10H13N5O5","free base","N/A","NC1=NC2=C(N=C[N]2C3OC(CO)C(O)C3O)C(=O)N1",-2.38,4,5,2]
["S2442","Inosine","e2","L1300-09","in 10mM DMSO","DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;CP2005;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease/Hematology/Immunology/Inflammation/Infection/Ophthalmology","Others","Others","Inosine (NSC 20262, INO 495) is a nucleoside that is formed when hypoxanthine is attached to a ribose ring via a β-N9-glycosidic bond.",268.23,"58-63-9",53,197.59,47,175.22,"http://selleckchem.com/products/inosine.html","C10H12N4O5","free base","NSC 20262, INO 495","OCC1OC(C(O)C1O)[N]2C=NC3=C2N=CNC3=O",-2.249,4,4,2]
["S2443","Tolbutamide (HLS 831)","f2","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","012678,086047,086109,086141,086445,086574,086926,087093,087121,087318,087541,087876,088893,088950,089110,089111","Endocrinology/Metabolic Disease","Potassium Channel","Transmembrane Transporters","Tolbutamide (HLS 831) is an inhibitor of potassium channel, used for type II diabetes.",270.35,"64-77-7",54,199.74,"<1",0,"http://selleckchem.com/products/tolbutamide.html","C12H18N2O3S","free base","HLS 831","CCCCNC(=O)N[S](=O)(=O)C1=CC=C(C)C=C1",2.336,3,2,5]
["S2446","Levosimendan","g2","L1300-09","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Levosimendan(OR1259,OR1855,Simsndan) is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC), provides treatment for heart failure.",280.28,"141505-33-1",56,199.8,"<1",0,"http://selleckchem.com/products/levosimendan.html","C14H12N6O","free base","OR1259,OR1855,Simsndan","CC1CC(=O)NN=C1C2=CC=C(NN=C(C#N)C#N)C=C2",1.486,3,2,3]
["S2450","Equol","h2","L1300-09","in 10mM DMSO","NDC",null,null,"Cancer","Estrogen/progestogen Receptor","Endocrinology & Hormones","Equol ,a metabolite of soybeans, is an important isoflavone in humans，specifically binds to 5α-DHT, has a modest affinity for recombinant estrogen receptor ERβ. Phase 2.",242.27,"531-95-3",48,198.13,"<1",0,"http://selleckchem.com/products/equol.html","C15H14O3","free base","N/A","OC1=CC=C(C=C1)C2COC3=CC(=CC=C3C2)O",3.211,1,2,1]
["S2451","Amantadine HCl","a3","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","070589,071293,071382,072655,073115,074028,074170,074509,075060,075819,076186,076352,077659,077992,078720,207570,207571,208096,208107,208278,208966,209035,209047,209171,209221,210403","Infection/Neurological Disease","Dopamine Receptor","Neuronal Signaling","Amantadine HCl (1-adamantanamine) is used to treat or prevent infections of the respiratory tract caused by a certain virus.",187.7,"665-66-7",38,202.45,38,202.45,"http://selleckchem.com/products/Amantadine-hydrochloride(Symmetrel).html","C10H17N.HCl","Hydrochloride","1-adamantanamine HCl","Cl.N[C]12CC3[CH2][CH](C[CH]([CH2]3)C1)C2",1.877,0,1,0]
["S2452","Amfebutamone (Bupropion) HCl","b3","L1300-09","in 10mM DMSO","CFDA",null,null,"Psychotic disorders","AChR,Dopamine Receptor","Neuronal Signaling","Amfebutamone (Bupropion) HCl(Wellbutrin) is a selective norepinephrine-dopamine reuptake inhibitor with IC50 of 6.5 and 3.4 μM for the reuptake of dopamine and norepinephrine, respectively.",276.2,"31677-93-7",8,28.96,"<1",0,"http://selleckchem.com/products/Amfebutamone-hydrochloride(Bupropion).html","C13H18ClNO.HCl","Hydrochloride","Wellbutrin","Cl.CC(NC(C)(C)C)C(=O)C1=CC=CC(=C1)Cl",3.501,1,1,4]
["S2454","Bupivacaine HCl","c3","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","018053,022046,070583,070584,070585,070586,070587,070590,070597,070609,071810,091503,207183,207266,209087,211096","Neurological Disease","Sodium Channel","Transmembrane Transporters","Bupivacaine HCl binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, used for treating cardiac arrhythmias.",324.89,"18010-40-7",65,200.07,23,70.79,"http://selleckchem.com/products/Bupivacaine-hydrochloride(Marcain).html","C18H28N2O.HCl","Hydrochloride","N/A","Cl.CCCCN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",4.692,1,1,5]
["S2455","Bethanechol chloride","d3","L1300-09","in 10mM DMSO","FDA,DMF,NDC,PMDA","USP42-NF37;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","040483,040485,040492,040509,040518,040532,040533,040534,040551,040552,040553,040554,040633,040634,040635,040636,040677,040721,040725,040726,040727,040728,040855,040897,084074,084353,084378,084379,084383,084384,084402,084408,084441,084689,084702,084712,085228,085229,085230,085839,085841,085842,087397,087444,088288,088289,089815,091256","Neurological Disease","AChR","Neuronal Signaling","Bethanechol chloride(Myocholine,Urecholine) is a selective muscarinic receptor agonist without any effect on nicotinic receptors.",196.68,"590-63-6",39,198.29,39,198.29,"http://selleckchem.com/products/Carbamyl-beta-methylcholine-chloride(Bethanechol-chloride).html","C7H17N2O2.Cl","quaternary-N Chloride salt","Myocholine,Urecholine","[Cl-].CC(C[N+](C)(C)C)OC(N)=O",-3.702,2,1,4]
["S2456","Chlorpromazine HCl","e3","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","040224,040231,080340,080365,080370,080403,080439,083329,083386,083549,083574,083575,084112,084113,084114,084115,084411,084412,084413,084414,084415,084789,084800,084801,084802,084803,084911,085331,085484,085591,085748,085750,085751,085752,085956,085957,085958,085959,085960,086712,086863,087032,087053,087645,087646,087783,087865,087878,087880,087884,088038,089563,209755","Psychotic disorders","Dopamine Receptor,Potassium Channel","Neuronal Signaling","Chlorpromazine HCl (Sonazine) is a dopamine and potassium channel inhibitor with IC50 of 6.1 and 16 μM for inward-rectifying K+ currents and time-independent outward currents.",355.33,"69-09-0",71,199.81,71,199.81,"http://selleckchem.com/products/Chlorpromazine-hydrochloride(Sonazine).html","C17H19ClN2S.HCl","Hydrochloride","Sonazine","Cl.CN(C)CCCN1C2=C(SC3=C1C=C(Cl)C=C3)C=CC=C2",5.121,0,0,4]
["S2457","Clindamycin HCl","f3","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37 ;EP9.3;BP2019;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","063027,063029,063082,063083,065061,065194,065217,065242,065243,065442,091225,207402","Infection/Parasitology","Bacterial","Microbiology","Clindamycin HCl inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.",461.44,"21462-39-5",92,199.38,92,199.38,"http://selleckchem.com/products/Clindamycin-hydrochloride(Dalacin).html","C18H33ClN2O5S.HCl","Hydrochloride","N/A","Cl.CCCC1CC(N(C)C1)C(=O)NC(C(C)Cl)C2OC(SC)C(O)C(O)C2O",1.659,2,4,7]
["S2458","Clonidine HCl","g3","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","070317,070395,070396,070397,070459,070460,070461,070659,070702,070747,070881,070882,070883,070886,070923,070963,070964,070965,070974,070975,070976,071101,071102,071103,071252,071253,071254,071785,072138,072139,072140,077901,078099,078895,090329,091104,091368,200300,200673,202297,202601,202792,202983,202984,203167,203320,209285,209675,209686,209757,210052,210338,210680,211433","Cardiovascular Disease/Neurological Disease","Adrenergic Receptor,Autophagy","Neuronal Signaling","Clonidine HCl(Kapvay) is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg.",266.5,"4205-91-8",53,198.87,53,198.87,"http://selleckchem.com/products/Clonidine-hydrochloride(Catapres).html","C9H9Cl2N3.HCl","Hydrochloride","Kapvay","Cl.ClC1=C(NC2=NCCN2)C(=CC=C1)Cl",2.736,1,2,2]
["S2459","Clozapine","h3","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","074546,074949,075162,075417,075713,076809,090308,201824,201824,202873,203039,203807,206433,209480","Psychotic disorders","5-HT Receptor","Neuronal Signaling","Clozapine (HF 1854, LX 100-129) is an atypical antipsychotic drug by acting as a 5-HT antagonist, used in the treatment of schizophrenia.",326.82,"5786-21-0",65,198.89,"<1",0,"http://selleckchem.com/products/Clozapine(Clozaril).html","C18H19ClN4","free base","HF 1854, LX 100-129","CN1CCN(CC1)C2=NC3=C(NC4=C2C=CC=C4)C=CC(=C3)Cl",3.422,1,1,1]
["S2460","Pramipexole","a4","L1300-09","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","077724,077854,078551,078894,078920,090151,090190,090241,090764,090781,090865,091254,091450,091683,201963,202164,202206,202353,202633,202702,202891,203354,203615,203855,204518,206156,207011,211088","Neurological Disease","Dopamine Receptor","Neuronal Signaling","Pramipexole (SND 919,Mirapexin,Sifrol,Mirapex) is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.",211.33,"104632-26-0",42,198.74,"<1",0,"http://selleckchem.com/products/Pramipexole-Mirapex.html","C10H17N3S","Free Base","SND 919,Mirapexin,Sifrol,Mirapex","CCCNC1CCC2=C(C1)SC(=N2)N",1.383,1,2,3]
["S2461","Domperidone","b4","L1300-09","in 10mM DMSO","DMF,CFDA,PMDA,HMA",";BP2019;EP9.2;KP Ⅹ;JP17;IP2010;CP2005;Martindale:The Extra Pharmacopoeia",null,"Gastroenterology","Dopamine Receptor","Neuronal Signaling","Domperidone is an oral dopamine D2 receptor antagonist, used to treat nausea and vomiting.",425.91,"57808-66-9",48,112.7,"<1",0,"http://selleckchem.com/products/Domperidone(Motilium).html","C22H24ClN5O2","free base","N/A","ClC1=CC2=C(C=C1)N(C3CCN(CCCN4C(=O)NC5=C4C=CC=C5)CC3)C(=O)N2",2.453,2,2,5]
["S2466","Estriol","c4","L1300-09","in 10mM DMSO","DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.5;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia",null,"Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estriol (NSC-12169) is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.",288.39,"50-27-1",57,197.65,"<1",0,"http://selleckchem.com/products/Estriol(Oestriol).html","C18H24O3","free base","NSC-12169","CC12CCC3C(CCC4=CC(=CC=C34)O)C1CC(O)C2O",2.871,0,3,0]
["S2467","Famciclovir","d4","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia;CP2005","077487,078278,090128,091114,091480,201022,201333,202438","Infection","Antiviral","Microbiology","Famciclovir (BRL-42810) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.",321.34,"104227-87-4",64,199.17,64,199.17,"http://selleckchem.com/products/Famciclovir(Famvir).html","C14H19N5O4","free base","BRL-42810","CC(=O)OCC(CC[N]1C=NC2=CN=C(N)N=C12)COC(C)=O",-0.294,7,1,9]
["S2468","Fenbendazole","e4","L1300-09","in 10mM DMSO","DMF","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","Parasite","Microbiology","Fenbendazole(Fenbendazol,Phenbendasol) is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL.",299.35,"43210-67-9",4,13.36,"<1",0,"http://selleckchem.com/products/Fenbendazole(Panacur).html","C15H13N3O2S","free base","Fenbendazol,Phenbendasol","COC(=O)NC1=NC2=C([NH]1)C=C(SC3=CC=CC=C3)C=C2",3.769,3,2,4]
["S2470","Fluocinolone Acetonide","f4","L1300-09","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","040035,040041,040042,040059,086810,086811,087102,087104,087159,088045,088046,088047,088048,088167,088168,088169,088170,088312,088361,088449,088499,088506,088507,088742,088756,088757,089124,089524,089525,089526,090982,091306,091514,201759,201764,202368,202705,202847,202848,202849,203377,203378,206422,207441,208386,209336,209596,209913,210747","Immunology/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Fluocinolone Acetonide (Flucort-N) is a corticosteroid that binds to the cytosolic glucocorticoid receptor.",452.5,"67-73-2",90,198.9,"<1",0,"http://selleckchem.com/products/Fluocinolone-acetonide(Flucort-N).html","C24H30F2O6","free base","Flucort-N","CC1(C)OC2CC3C4CC(F)C5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(O1)C(=O)CO",0.995,4,2,2]
["S2471","Gallamine Triethiodide","g4","L1300-09","in 10mM DMSO","FDA","USP42-NF37;KP Ⅹ;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","007842","Neurological Disease","AChR","Neuronal Signaling","Gallamine Triethiodide  is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM.",891.53,"65-29-2",100,112.17,100,112.17,"http://selleckchem.com/products/Gallamine-triethiodide(Flaxedil).html","C30H60I3N3O3","tri-quaternary-N iodide salt","N/A","[I-].[I-].[I-].CC[N+](CC)(CC)CCOC1=C(OCC[N+](CC)(CC)CC)C(=CC=C1)OCC[N+](CC)(CC)CC",-8.065,3,0,21]
["S2473","Hexestrol","h4","L1300-09","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Hexestrol (Bibenzyl) binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.",270.37,"84-16-2",42,155.34,"<1",0,"http://selleckchem.com/products/Hexestrol(Bibenzyl).html","C18H22O2","free base","Bibenzyl","CCC(C(CC)C1=CC=C(O)C=C1)C2=CC=C(O)C=C2",5.192,0,2,5]
["S2475","Imatinib (STI571)","a5","L1300-09","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","078340,079179,204285,204644,205990,206547,207495,207586,207818,208302,208429","Cancer/Hematology","Autophagy,Bcr-Abl,c-Kit,PDGFR","Protein Tyrosine Kinase","Imatinib (STI571,Gleevec, Glivec, CGP057148B) is a multi-target inhibitor of tyrosine kinase with inhibition for v-Abl, c-Kit and PDGFR, IC50 values are 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib (STI571) induces autophagy.",493.6,"152459-95-5",33,66.86,"<1",0,"http://selleckchem.com/products/Imatinib(STI571).html","C29H31N7O","free base","STI571,Gleevec, Glivec, CGP057148B","CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC=C(C)C(=C3)NC4=NC=CC(=N4)C5=CC=CN=C5",4.22,4,2,7]
["S2479","Lincomycin HCl","b5","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","062784","Infection","Antibiotics for Mammalian Cell Culture,Anti-infection","Microbiology","Lincomycin  hydrochloride (Lincocin, NSC 70731,U10149A) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis.",443,"859-18-7",89,200.9,89,200.9,"http://selleckchem.com/products/Lincomycin-hydrochloride(Lincocin).html","C18H34N2O6S.HCl","Hydrochloride","Lincocin, NSC 70731,U10149A","Cl.CCCC1CC(N(C)C1)C(=O)NC(C(C)O)C2OC(SC)C(O)C(O)C2O",0.454,2,5,7]
["S2480","Loperamide HCl","c5","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.8;BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia","021855,072741,072993,073062,073079,073080,073122,073187,073192,073243,073254,073478,073528,074091,074194,074352,074730,074991,075232,076497,091292,206548","Gastroenterology","Autophagy,Opioid Receptor","Neuronal Signaling","Loperamide HCl (ADL 2-1294,R-18553 hydrochloride) is a selective μ-opioid receptor agonist opioid with Ki of 3.3 nM, 15-fold and 350-fold selective over the δ subtype and the κ subtype of the opioid receptor, used against diarrhea resulting from gastroenteritis or inflammatory bowel disease.",513.5,"34552-83-5",22,42.84,"<1",0,"http://selleckchem.com/products/Loperamide-hydrochloride.html","C29H33ClN2O2.HCl","Hydrochloride","ADL 2-1294,R-18553 hydrochloride","Cl.CN(C)C(=O)C(CCN1CCC(O)(CC1)C2=CC=C(Cl)C=C2)(C3=CC=CC=C3)C4=CC=CC=C4",5.017,1,0,7]
["S2481","Manidipine","d5","L1300-09","in 10mM DMSO","CFDA,PMDA,HMA","JP17;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Manidipine(CV-4093,(±)-Manidipine) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive.",610.7,"89226-50-6",122,199.77,"<1",0,"http://selleckchem.com/products/Manidipine(Manyper).html","C35H38N4O6","free base","CV-4093,(±)-Manidipine","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OCCN3CCN(CC3)C(C4=CC=CC=C4)C5=CC=CC=C5)C",5.058,4,1,12]
["S2482","Manidipine 2HCl","e5","L1300-09","in 10mM DMSO","CFDA,PMDA,HMA","JP17;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Manidipine 2HCl (CV-4093) is a HCl salt form of Manidipine, which is a calcium channel blocker with IC50 of 2.6 nM, used clinically as an antihypertensive. Phase 4.",683.62,"89226-75-5",21,30.72,"<1",0,"http://selleckchem.com/products/Manidipine-dihydrochloride(CV-4093).html","C35H38N4O6.2HCl","Dihydrochloride","CV-4093","Cl.Cl.COC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OCCN3CCN(CC3)C(C4=CC=CC=C4)C5=CC=CC=C5)C",5.822,4,1,12]
["S2484","Milrinone","f5","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","075510,075834,075885,076259,076414,077151,078113","Cardiovascular Disease","PDE","Metabolism","Milrinone (Win 47203,Primacor) is a phosphodiesterase 3 (PDE3) inhibitor, used to increase the heart's contractility.",211.22,"78415-72-2",42,198.84,"<1",0,"http://selleckchem.com/products/Milrinone(Primacor).html","C12H9N3O","free base","Win 47203,Primacor","CC1=C(C=C(C#N)C(=O)N1)C2=CC=NC=C2",0.356,2,1,1]
["S2485","Mitoxantrone (NSC-301739) 2HCl","g5","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","076611,076871,077356,077496,078606,078980,201014","Cancer/Hematology","Apoptosis related,COVID-19,PKC,Topoisomerase","DNA Damage/DNA Repair","Mitoxantrone 2HCl (NSC-301739) is a dihydrochloride salt of Mitoxantrone. Mitoxantrone is an inhibitor of type II topoisomerase and protein kinase C (PKC) with IC50 of 8.5 μM for PKC. Mitoxantrone inhibits cell proliferative growth of MCF-7/wt cells with IC50 of 0.42 μM. Mitoxantrone also induces apoptosis.",517.4,"70476-82-3",89,172.01,89,172.01,"http://selleckchem.com/products/Mitoxantrone-Hydrochloride.html","C22H29ClN4O6.2HCl","Dihydrochloride","NSC-301739 2HCl","Cl.Cl.OCCNCCNC1=CC=C(NCCNCCO)C2=C1C(=O)C3=C(O)C=CC(=C3C2=O)O",0.832,2,8,12]
["S2486","Moroxydine HCl","h5","L1300-09","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Infection","Antiviral","Microbiology","Moroxydine HCl(ABOB hydrochloride) is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines.",207.66,"3160-91-6",42,202.25,42,202.25,"http://selleckchem.com/products/Moroxydine-hydrochloride.html","C6H13N5O.HCl","Hydrochloride","ABOB hydrochloride","Cl.NC(=N)NC(=N)N1CCOCC1",-0.672,1,2,3]
["S2487","Mycophenolic acid","a6","L1300-09","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","091248,091558,202555,202720","Immunology","Antineoplastic and Immunosuppressive Antibiotics,Dehydrogenase,Selection Antibiotics for Transfected Cell","Metabolism","Mycophenolic acid (Mycophenolate, RS-61443) is a potent IMPDH inhibitor and the active metabolite of an immunosuppressive drug, used to prevent rejection in organ transplantation.",320.34,"24280-93-1",64,199.79,"<1",0,"http://selleckchem.com/products/Mycophenolic-acid(Mycophenolate).html","C17H20O6","free base","Mycophenolate, RS-61443","COC1=C(C)C2=C(C(=C1C\\C=C(/C)CCC(O)=O)O)C(=O)OC2",3.157,4,1,6]
["S2489","Nateglinide","b6","L1300-09","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","077461,077462,077463,077467,205055,205248,205544,206432","Endocrinology/Metabolic Disease","Potassium Channel","Transmembrane Transporters","Nateglinide (Starlix,A-4166,SDZ DJN 608) is an insulin secretagog agent that lowers blood glucose levels by stimulating insulin secretion from the pancreas.",317.42,"105816-04-4",63,198.48,"<1",0,"http://selleckchem.com/products/Nateglinide(Starlix).html","C19H27NO3","free base","Starlix,A-4166,SDZ DJN 608","CC(C)C1CCC(CC1)C(=O)NC(CC2=CC=CC=C2)C(O)=O",3.981,2,1,6]
["S2491","Nitrendipine","c6","L1300-09","in 10mM DMSO","DMF,CFDA,PMDA,HMA","BP2019;EP9.2;KP Ⅹ;JP17;CP2005;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Autophagy,Calcium Channel","Transmembrane Transporters","Nitrendipine (Bayotensin) is a dihydropyridine calcium channel blocker with an IC50 of 95 nM.",360.37,"39562-70-4",72,199.79,"<1",0,"http://selleckchem.com/products/Nitrendipine.html","C18H20N2O6","free base","Bayotensin","CCOC(=O)C1=C(C)NC(=C(C1C2=CC(=CC=C2)[N+]([O-])=O)C(=O)OC)C",2.115,4,1,7]
["S2492","Novobiocin Sodium (NSC 2382)","d6","L1300-09","in 10mM DMSO","FDA,DMF","USP42-NF37;IP2010;Martindale:The Extra Pharmacopoeia","050339","Infection","Antineoplastic and Immunosuppressive Antibiotics,Topoisomerase","DNA Damage/DNA Repair","Novobiocin Sodium (NSC 2382, Albamycin, Cathomycin) is an aminocoumarin antibiotic that targets bacterial DNA gyrase (TopoIV), used to treat susceptible gram positive bacteria.",634.61,"1476-53-5",100,157.58,100,157.58,"http://selleckchem.com/products/Novobiocin-sodium(Albamycin).html","C31H35N2O11.Na","Sodium Salt","Albamycin,Cathomycin,NSC 2382","[Na+].COC1C(OC(N)=O)C(O)C(OC2=CC=C3C(=C(NC(=O)C4=CC=C([O-])C(=C4)CC=C(C)C)C(=O)OC3=C2C)O)OC1(C)C",2.747,8,4,9]
["S2493","Olanzapine","e6","L1300-09","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","076000,076133,076255,076534,076866,077243,077301,077993,078109,090459,090798,090881,091038,091265,091415,091434,200221,201588,201741,202050,202285,202287,202295,202862,202937,203044,203333,203456,203708,204319,204320,204866,206238,206711,208146,209399","Psychotic disorders","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Olanzapine (LY170053,Zyprexa, Zalasta, Zolafren, Olzapin, Oferta, Zypadhera) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist.",312.44,"132539-06-1",62,198.44,"<1",0,"http://selleckchem.com/products/Olanzapine(Zyprexa).html","C17H20N4S","free base","LY170053,Zyprexa, Zalasta, Zolafren, Olzapin, Oferta, Zypadhera","CN1CCN(CC1)C2=NC3=C(NC4=C2C=C(C)S4)C=CC=C3",2.69,1,1,1]
["S2494","Olopatadine HCl","f6","L1300-09","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;JP17;Martindale:The Extra Pharmacopoeia","078350,090848,090918,090972,091572,200810,202526,202853,203152,203416,204392,204532,204706,204723,204812,206046,206087,206306,209015,209420,209919,209995","Immunology/Inflammation","Histamine Receptor","Neuronal Signaling","Olopatadine HCl(ALO4943A,KW4679) is a histamine blocker and mast cell stabilizer with an IC50 of 559 μM for the release of histamine.",373.87,"140462-76-6",75,200.6,13,34.77,"http://selleckchem.com/products/Olopatadine-hydrochloride(Opatanol).html","C21H23NO3.HCl","Hydrochloride","ALO4943A,KW4679","Cl.CN(C)CC\\C=C/1C2=C(COC3=C1C=C(CC(O)=O)C=C3)C=CC=C2",0.92,2,0,5]
["S2496","Ozagrel","g6","L1300-09","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Ophthalmology","P450 (e.g. CYP17),Prostaglandin Receptor","GPCR & G Protein","Ozagrel (OKY-046) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.",228.25,"82571-53-7",46,201.53,"<1",0,"http://selleckchem.com/products/Ozagrel.html","C13H12N2O2","free base","OKY-046","OC(=O)/C=C/C1=CC=C(C[N]2C=CN=C2)C=C1",1.604,2,0,4]
["S2497","Pancuronium dibromide","h6","L1300-09","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","072058,072059,072060,072208,072209,072210,072211,072212,072213,072320,072321,072759,072760","Neurological Disease","AChR","Neuronal Signaling","Pancuronium dibromide(Pavulon) is a competitive nicotinic acetylcholine receptor antagonist, used as a muscle relaxant.",732.67,"15500-66-0",100,136.49,100,136.49,"http://selleckchem.com/products/Pancuronium-bromide(Pavulon).html","C35H60N2O4.2Br","di-quaternary-N bromide salt","Pavulon","[Br-].[Br-].CC(=O)OC1CC2CCC3C(CCC4(C)C3CC(C4OC(C)=O)[N+]5(C)CCCCC5)C2(C)CC1[N+]6(C)CCCCC6",-2.043,4,0,6]
["S2499","Phenoxybenzamine HCl","a7","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","201050,204522","Cancer/Cardiovascular Disease","Adrenergic Receptor","GPCR & G Protein","Phenoxybenzamine HCl (NSC 37448, NCI-c01661) is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.",340.3,"63-92-3",68,199.82,17,49.96,"http://selleckchem.com/products/Phenoxybenzamine-hydrochloride.html","C18H22ClNO.HCl","HCl","NSC 37448, NCI-c01661","Cl.CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2",4.96,1,0,8]
["S2500","Propafenone HCl","b7","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","075203,075938,075998,076193,076550,078540,202445,202688,203803,205268,205956,210339","Cardiovascular Disease","Sodium Channel","Transmembrane Transporters","Propafenone HCl is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias.",377.9,"34183-22-7",69,182.59,"<1",0,"http://selleckchem.com/products/Propafenone(Rytmonorm).html","C21H27NO3.HCl","Hydrochloride","N/A","CCCNCC(O)COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2",3.673,2,2,11]
["S2501","Pyrantel Pamoate","c7","L1300-09","in 10mM DMSO","DMF,CFDA,NDC,PMDA","USP42-NF37;KP Ⅹ;JP17;Ph.Int_5th;IP2010;CP2005",null,"Infection/Parasitology","Parasite","Microbiology","Pyrantel pamoate (Pyrantel Embonate), a broad-spectrum anthelmintic drug, is used to treat a number of parasitic worm infections.",594.69,"22204-24-6",100,168.15,"<1",0,"http://selleckchem.com/products/Pyrantel-pamoate(Pyrantel-embonate).html","C23H16O6.C11H14N2S","salt","Pyrantel Embonate","CN1CCCN=C1\\C=C\\C2=CC=CS2.OC(=O)C3=CC4=CC=CC=C4C(=C3O)CC5=C6C=CC=CC6=CC(=C5O)C(O)=O",6.203,3,2,6]
["S2502","Quinine HCl Dihydrate","d7","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","091661,202581,203112,203729,204372","Infection/Parasitology","Potassium Channel","Transmembrane Transporters","Quinine HCl Dihydrate is a white crystalline K+ channel blocker, used to treat malaria.",396.91,"6119-47-7",79,199.04,43,108.34,"http://selleckchem.com/products/Quinine-hydrochloride-dihydrate.html","C20H24N2O2.HCl.2H2O","Hydrochloride dihydrate","N/A","O.O.Cl.COC1=CC2=C(C=C1)N=CC=C2C(O)C3CC4CCN3CC4C=C",2.701,2,1,4]
["S2503","Racecadotril","e7","L1300-09","in 10mM DMSO","CFDA,HMA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Gastroenterology","Opioid Receptor","Neuronal Signaling","Racecadotril (Acetorphan) is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 μM.",385.48,"81110-73-8",22,57.07,"<1",0,"http://selleckchem.com/products/Racecadotril(Acetorphan).html","C21H23NO4S","free base","Acetorphan","CC(=O)SCC(CC1=CC=CC=C1)C(=O)NCC(=O)OCC2=CC=CC=C2",3.128,4,1,11]
["S2504","Ribavirin (ICN-1229)","f7","L1300-09","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;CP2005;Martindale:The Extra Pharmacopoeia","076192,076277,077053,077094,077224,077456,077611,077743,079111,079117,202546,207366","Infection","Antiviral","Microbiology","Ribavirin (NSC-163039, ICN-1229, RTCA, Tribavirin), a synthetic guanosine analogue, possesses a broad spectrum of activity against DNA and RNA viruses.",244.21,"36791-04-5",49,200.65,49,200.65,"http://selleckchem.com/products/Ribavirin(Copegus).html","C8H12N4O5","free base","NSC-163039, RTCA, Tribavirin","NC(=O)C1=N[N](C=N1)C2OC(CO)C(O)C2O",-2.745,4,4,3]
["S2505","Rosiglitazone (BRL-49653) maleate","g7","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;IP2010;Martindale:The Extra Pharmacopoeia","076747,078658,078674,078695,078825","Endocrinology/Metabolic Disease","Autophagy,Ferroptosis,PPAR,TRP Channel","Metabolism","Rosiglitazone maleate (BRL-49653C), a member of the thiazolidinedione class of antihyperglycaemic agents, is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-γ (PPAR-γ) with IC50 of 42 nM. Rosiglitazone maleate also modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis.",473.5,"155141-29-0",94,198.52,"<1",0,"http://selleckchem.com/products/Rosiglitazone-maleate.html","C18H19N3O3S.C4H4O4","Maleate","BRL-49653C","CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C3=NC=CC=C3.OC(=O)\\C=C/C(O)=O",3.307,6,1,9]
["S2506","Roxithromycin","h7","L1300-09","in 10mM DMSO","CFDA,PMDA,HMA","BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia;CP2005",null,"Infection","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics","Microbiology","Roxithromycin (Roxl-150, Roxo, Surlid, Rulide, Biaxsig, Roxar, Roximycin, Roxomycin, Tirabicin, Coroxin,RU-28965) is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections.",837.07,"80214-83-1",167,199.51,"<1",0,"http://selleckchem.com/products/Roxithromycin(Roxl-150).html","C41H76N2O15","free base","Roxl-150, Roxo, Surlid, Rulide, Biaxsig, Roxar, Roximycin, Roxomycin, Tirabicin, Coroxin,RU-28965","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)C(=N/OCOCCOC)/C(C)C(O)C1(C)O",1.619,11,3,13]
["S2508","Scopolamine (LSM-4015) HBr","a8","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;KP Ⅹ;EP9.2;JP17;IP2010;CP2005","078830","Cardiovascular Disease/Neurological Disease","AChR","Neuronal Signaling","Scopolamine HBr (LSM-4015,NSC 61806,(-)-Scopolamine hydrobromide, Hyoscine hydrobromide, Scopine hydrobromide) is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55.3 nM.",384.26,"114-49-8",76,197.78,76,197.78,"http://selleckchem.com/products/Scopolamine-hydrobromide.html","C17H21NO4.HBr","Hydrobromide","LSM-4015,NSC 61806,(-)-Scopolamine hydrobromide, Hyoscine hydrobromide, Scopine hydrobromide","Br.CN1C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",1.314,3,1,5]
["S2509","Sotalol HCl","b8","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","022306,075237,075238,075366,075429,075515,075563,075663,075725,076140,076214,076576,076883,077070,077616,207428,207429","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Sotalol(MJ-1999)  is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 μM.",308.82,"959-24-0",61,197.53,61,197.53,"http://selleckchem.com/products/Sotalol-hydrochloride(Betapace).html","C12H20N2O3S.HCl","Hydrochloride","MJ-1999","Cl.CC(C)NCC(O)C1=CC=C(N[S](C)(=O)=O)C=C1",0.876,2,3,6]
["S2510","Spectinomycin 2HCl","c8","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","050347","Infection","Antibiotics,Antibiotics for Mammalian Cell Culture,Selection Antibiotics for Transfected Cell","Microbiology","Spectinomycin 2HCl (Actinospectacin) is a new parenteral antibiotic prepared from Streptomyces spectabilis.",405.27,"21736-83-4",81,199.87,81,199.87,"http://selleckchem.com/products/Spectinomycin-hydrochloride.html","C14H24N2O7.2HCl","dihydrochloride","Actinospectacin","Cl.Cl.CNC1C(O)C(NC)C2OC3(O)C(OC(C)CC3=O)OC2C1O",-1.566,4,4,2]
["S2511","Sulfadoxine","d8","L1300-09","in 10mM DMSO","FDA,DMF,CFDA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;Martindale:The Extra Pharmacopoeia","018557","Infection/Parasitology","Anti-infection","Microbiology","Sulfadoxine (Sulphadoxine) is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax.",310.33,"2447-57-6",62,199.78,"<1",0,"http://selleckchem.com/products/Sulfadoxine(Sulphadoxine).html","C12H14N4O4S","free base","Sulphadoxine","COC1=C(OC)C(=NC=N1)N[S](=O)(=O)C2=CC=C(N)C=C2",0.837,6,2,5]
["S2512","Tenoxicam","e8","L1300-09","in 10mM DMSO","marketed in Japan","EP9.4;BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia",null,"Immunology/Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Tenoxicam(Ro-12-0068) is a good HO. radicals scavenger with an IC50 of 56.7 μM.",337.38,"59804-37-4",68,201.55,"<1",0,"http://selleckchem.com/products/Tenoxicam(Mobiflex).html","C13H11N3O4S2","free base","Ro-12-0068","CN1C(=C(O)C2=C(C=CS2)[S]1(=O)=O)C(=O)NC3=CC=CC=N3",0.454,4,2,2]
["S2515","Vardenafil HCl Trihydrate","f8","L1300-09","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","091347,203689,204632,204786,205988,208324,208960,209057,210738","Others","PDE","Metabolism","Vardenafil HCl Trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.",579.11,"330808-88-3",100,172.68,10,17.27,"http://selleckchem.com/products/Vardenafil(Vivanza).html","C23H32N6O4S.HCl.3H2O","Hydrochloride trihydrate","BAY38-9456","O.O.O.Cl.CCCC1=NC(=C2[N]1N=C(NC2=O)C3=CC(=CC=C3OCC)[S](=O)(=O)N4CCN(CC)CC4)C",2.109,6,1,8]
["S2516","Xylazine HCl","g8","L1300-09","in 10mM DMSO","DMF","USP42-NF37;EP9.8;BP2019;Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Adrenergic Receptor","Neuronal Signaling","Xylazine(BAY 1470 hydrochloride) is an α2-Adrenergic receptor agonist, used as a sedative and muscle relaxant.",256.79,"23076-35-9",50,194.71,12,46.73,"http://selleckchem.com/products/Xylazine(Rompun).html","C12H16N2S.HCl","Hydrochloride","BAY 1470 hydrochloride","Cl.CC1=C(NC2=NCCCS2)C(=CC=C1)C",3.647,1,1,2]
["S2517","Maprotiline HCl","h8","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","071943,071944,071945,072129,072130,072131,072162,072163,072164,072285","Psychotic disorders","Adrenergic Receptor","Neuronal Signaling","Maprotiline HCl is a selective noradrenalin re-uptake inhibitor, used in the treatment of depression.",313.86,"10347-81-6",63,200.73,"<1",0,"http://selleckchem.com/products/Maprotiline-hydrochloride.html","C20H23N.HCl","Hydrochloride","N/A","Cl.CNCCCC12CCC(C3=CC=CC=C13)C4=C2C=CC=C4",4.498,0,1,4]
["S2519","Naphazoline HCl","a9","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;IP2010;CP2005;Martindale:The Extra Pharmacopoeia","083590","Angiology/Ophthalmology","Adrenergic Receptor","Neuronal Signaling","Naphazoline HCl is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.",246.74,"550-99-2",17,68.9,49,198.59,"http://selleckchem.com/products/Naphazoline-hydrochloride-Naphcon.html","C14H14N2.HCl","Hydrochloride","N/A","Cl.C1CN=C(CC2=C3C=CC=CC3=CC=C2)N1",2.442,1,1,2]
["S2521","Epinephrine bitartrate","b9","L1300-09","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;IP2010","016126","Immunology/Inflammation/Neurological Disease","Adrenergic Receptor","GPCR & G Protein","Epinephrine bitartrate (Adrenalinium) is an alpha- and beta-adrenergic receptor stimulator.",333.29,"51-42-3",67,201.03,67,201.03,"http://selleckchem.com/products/Epinephrine-bitartrate-Adrenalinium.html","C9H13NO3.C4H6O6","tartrate","Adrenalinium","CNCC(O)C1=CC(=C(O)C=C1)O.OC(C(O)C(O)=O)C(O)=O",-3.996,2,6,6]
["S2524","Phenytoin Sodium","c9","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","BP2019;EP9.6;KP Ⅹ ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","040573,040781,084307,085434,085435,085894,088519,088520,088521,089003,089501,089521,089744,089779,089900,204309","Cardiovascular Disease/Neurological Disease","Sodium Channel","Transmembrane Transporters","Phenytoin Sodium (Aleviatin, Diphenylhydantoin sodium, Eptoin, Phenytoin soluble, Prompt; Phenytek,Dilantin sodium, Diphantoine) is an inactive voltage-gated sodium channel stabilizer.",274.25,"630-93-3",32,116.68,3,10.94,"http://selleckchem.com/products/Phenytoin-sodium-Dilantin.html","C15H11N2NaO2","Sodium Salt","Aleviatin, Diphenylhydantoin sodium, Eptoin, Phenytoin soluble, Prompt,Phenytek,Dilantin sodium, Diphantoine","[Na+].[O-]C1=NC(=O)C(N1)(C2=CC=CC=C2)C3=CC=CC=C3",2.084,2,1,2]
["S2525","Phenytoin","d9","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","BP2019;EP9.6;KP Ⅹ ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","040342,040420,040521,040610,040884,089892,200565,200691","Cardiovascular Disease/Neurological Disease","Sodium Channel","Transmembrane Transporters","Phenytoin (Di-Hydan, Dihycon, Dilabid, Diphedan, Diphenat, Diphenylan, Diphenylhydantoin, Hydantol, Lehydan, NSC 8722) is an inactive voltage-gated sodium channel stabilizer.",252.27,"57-41-0",50,198.2,"<1",0,"http://selleckchem.com/products/Phenytoin-Lepitoin.html","C15H12N2O2","Free Base","Di-Hydan, Dihycon, Dilabid, Diphedan, Diphenat, Diphenylan, Diphenylhydantoin, Hydantol, Lehydan, NSC 8722","O=C1NC(=O)C(N1)(C2=CC=CC=C2)C3=CC=CC=C3",2.105,2,2,2]
["S2528","Ciclopirox","e9","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","020519,076422,076435,076790,077092,077364,077623,077676,077687,077896,078046,078079,078124,078144,078172,078233,078266,078270,078463,078567,078594,078975,090146,090269,090273,090490,091595,209975","Infection","ATPase,Fungal","Transmembrane Transporters","Ciclopirox(HOE 296b, Penlac) is a broad-spectrum antifungal agent working as an iron chelator.",207.27,"29342-05-0",42,202.63,"<1",0,"http://selleckchem.com/products/Ciclopirox-Penlac.html","C12H17NO2","Free Base","HOE 296b, Penlac","CC1=CC(=O)N(O)C(=C1)C2CCCCC2",2.489,1,0,1]
["S2529","Dopamine HCl","f9","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Ph.Int_6th;Martindale:The Extra Pharmacopoeia","018014,018132,018138,018398,018549,018656,070011,070012,070013,070046,070047,070058,070059,070087,070089,070090,070091,070092,070093,070094,070364,070558,070559,070656,070657,070799,070820,070826,072999,073000,074403,207707","Neurological Disease","Dopamine Receptor","Neuronal Signaling","Dopamine HCl(ASL279, NSC 173182) is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.",189.64,"62-31-7",38,200.38,38,200.38,"http://selleckchem.com/products/Dopamine-hydrochloride-Inotropin.html","C8H11NO2.HCl","Hydrochloride","ASL279, NSC 173182","Cl.NCCC1=CC(=C(O)C=C1)O",1.155,0,3,2]
["S2532","L-Ascorbyl 6-palmitate","g9","L1300-09","in 10mM DMSO",null,"USP42-NF37",null,"Cancer",0,"Others","Ascorbyl palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C.",414.53,"137-66-6",83,200.23,"<1",0,"http://selleckchem.com/products/L-Ascorbyl-6-palmitate.html","C22H38O7","free base","N/A","CCCCCCCCCCCCCCCC(=O)OCC(O)C1OC(=O)C(=C1O)O",5.268,4,3,18]
["S2533","Ritodrine HCl","h9","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,PMDA","USP42-NF37;BP2019;JP17;Martindale:The Extra Pharmacopoeia","070700,070701,071188,071189,071618,071619","Neurological Disease","Adrenergic Receptor","Neuronal Signaling","Ritodrine HCl (NSC 291565,DU 21220, Ritodrine) is a hydrochloride salt of ritodrine which is a β-2 adrenergic receptor agonist.",323.81,"23239-51-2",65,200.73,65,200.73,"http://selleckchem.com/products/Ritodrine-hydrochloride-Yutopar.html","C17H21NO3.HCl","Hydrochloride","NSC 291565,DU 21220, Ritodrine","Cl.CC(NCCC1=CC=C(O)C=C1)C(O)C2=CC=C(O)C=C2",3.037,0,4,6]
["S2534","Isoconazole nitrate","a10","L1300-09","in 10mM DMSO","PMDA","BP2019;EP9.2;KP Ⅹ;Martindale:The Extra Pharmacopoeia",null,"Infection","Fungal","Microbiology","Isoconazole nitrate (Travogen,Adestan G 100, R 15454) is an azole antifungal reagent.",479.14,"24168-96-5",41,85.57,"<1",0,"http://selleckchem.com/products/Isoconazole-nitrate-Travogen.html","C18H14Cl4N2O.HNO3","Nitrate","Travogen,Adestan G 100, R 15454","O[N+]([O-])=O.ClC1=CC=C(C(C[N]2C=CN=C2)OCC3=C(Cl)C=CC=C3Cl)C(=C1)Cl",4.387,2,0,6]
["S2535","Econazole nitrate","b10","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia;CP2005","076005,076075,076479,076574,210364","Infection","Calcium Channel,Fungal","Transmembrane Transporters","Econazole Nitrate (NSC 243115,Spectazole) is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus.",444.7,"24169-02-6",89,200.13,"<1",0,"http://selleckchem.com/products/Econazole-nitrate-Spectazole.html","C18H15Cl3N2O.HNO3","Nitrate","NSC 243115,Spectazole","O[N+]([O-])=O.ClC1=CC=C(COC(C[N]2C=CN=C2)C3=CC=C(Cl)C=C3Cl)C=C1",3.722,2,0,6]
["S2536","Miconazole","c10","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.7;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","074926,076773,074164,076585,073507,073508,074030,074136,074366,074395,074414,074444,074760,079114,091366","Infection","Fungal","Microbiology","Miconazole (Monistat,R18134) is an imidazole antifungal agent.",416.13,"22916-47-8",83,199.46,"<1",0,"http://selleckchem.com/products/Miconazole-Monistat.html","C18H14Cl4N2O","Free Base","Monistat,R18134","ClC1=CC=C(COC(C[N]2C=CN=C2)C3=C(Cl)C=C(Cl)C=C3)C(=C1)Cl",5.645,2,0,6]
["S2537","Secnidazole","d10","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC","IP2010;Martindale:The Extra Pharmacopoeia","209363","Infection","Anti-infection","Microbiology","Secnidazole (Flagentyl, PM 185184, RP 14539) is a nitroimidazole anti-infective.",185.18,"3366-95-8",37,199.81,37,199.81,"http://selleckchem.com/products/Secnidazole-Flagentyl.html","C7H11N3O3","free base","PM 185184, RP 14539","CC(O)C[N]1C(=NC=C1[N+]([O-])=O)C",0.04,1,1,3]
["S2541","Clomipramine HCl","e10","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","074364,074600,074694,074751,074849,074947,074953,074958,208632,208961,209294,211767","Neurological Disease/Psychotic disorders","Serotonin Transporter","Neuronal Signaling","Clomipramine HCl(Anafranil) is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively.",351.31,"17321-77-6",70,199.25,70,199.25,"http://selleckchem.com/products/Clomipramine-hydrochloride-Anafranil.html","C19H23ClN2.HCl","Hydrochloride","Anafranil","Cl.CN(C)CCCN1C2=C(CCC3=C1C=C(Cl)C=C3)C=CC=C2",5.434,0,0,4]
["S2543","Ceftiofur HCl","g10","L1300-09","in 10mM DMSO",null,"USP42-NF37;Martindale:The Extra Pharmacopoeia",null,"Infection","Antibiotics,Bacterial","Microbiology","Ceftiofur HCl (U-67279A,Excenel hydrochloride) is a cephalosporin antibiotic, used to treat both Gram-positive and Gram-negative bacteria infection.",560.02,"103980-44-5",100,178.57,"<1",0,"http://selleckchem.com/products/Ceftiofur-hydrochloride.html","C19H17N5O7S3.HCl","Hydrochloride","U-67279A,Excenel hydrochloride","Cl.CO/N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)CSC(=O)C3=CC=CO3)C4=CSC(=N4)N",1.09,8,2,9]
["S2547","Tiotropium Bromide hydrate","h10","L1300-09","in 10mM DMSO","FDA,CFDA,DMF,NDC,PMDA,HMA","BP2019;EP9.3;IP2010;Martindale:The Extra Pharmacopoeia","021395","Immunology/Respiratory Disease","AChR","Neuronal Signaling","Tiotropium Bromide hydrate (BA 679BR) is a monohydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a muscarinic receptor antagonist.",490.43,"139404-48-1",8,16.31,"<1",0,"http://selleckchem.com/products/Tiotropium-Bromide-hydrate.html","C19H22NO4S2.Br.xH2O","quaternary-N bromide salt&hydr","BA 679BR","O.[Br-].C[N+]1(C)C2CC(CC1C3OC23)OC(=O)C(O)(C4=CC=CS4)C5=CC=CS5",-1.727,3,0,5]
["S2549","Trospium chloride","a11","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","091289,091513,091573,091575,091635,091688,201291,204945","Others","AChR","Neuronal Signaling","Trospium chloride  is a competitive muscarinic cholinergic receptor antagonist.",427.96,"10405-02-4",41,95.8,86,200.95,"http://selleckchem.com/products/Trospium-chloride-Sanctura.html","C25H30NO3.Cl","quaternary-N chloride salt","N/A","[Cl-].OC(C(=O)OC1CC2CCC(C1)[N+]23CCCC3)(C4=CC=CC=C4)C5=CC=CC=C5",-0.324,2,0,5]
["S2551","Sulbactam sodium","b11","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","BP2019;EP9.2;KP Ⅹ;JP17;CP2005;Martindale:The Extra Pharmacopoeia","050608,06290","Infection","β-lactamase","Microbiology","Sulbactam sodium (Unasyn, CP-45899-2) is an irreversible β-lactamase inhibitor.",255.22,"69388-84-7",3,11.75,51,199.83,"http://selleckchem.com/products/sulbactam-sodium-unasyn.html","C8H10NO5S.Na","Sodium  salt","Unasyn, CP-45899-2","[Na+].CC1(C)C(N2C(CC2=O)[S]1(=O)=O)C([O-])=O",-2.145,3,0,1]
["S2552","Azelastine HCl","c11","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","077954,078621,078738,090176,090423,091409,091444,201846,201999,202305,202609,202743,203660,204660,207243,207411,207610,208156,208199,209620","Immunology/Inflammation/Ophthalmology","Histamine Receptor","Neuronal Signaling","Azelastine HCl is a potent, second-generation, selective, histamine receptor antagonist, used in the treatment of rhinitis.",418.36,"79307-93-0",28,66.93,35,83.66,"http://selleckchem.com/products/azelastine.html","C22H24ClN3O.HCl","Hydrochloride","N/A","Cl.CN1CCCC(CC1)N2N=C(CC3=CC=C(Cl)C=C3)C4=CC=CC=C4C2=O",4.476,2,0,3]
["S2553","5-Aminolevulinic acid HCl","d11","L1300-09","in 10mM DMSO","DMF,EMA","Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","5-Aminolevulinic Acid HCl(5-ALA hydrochloride) is an intermediate in the porphyrin synthesis pathway, used as a photosensitizing agent and a antineoplastic agent.",167.59,"5451-09-2",34,202.88,34,202.88,"http://selleckchem.com/products/5-Aminolevulinic-acid-hydrochloride.html","C5H9NO3.HCl","Hydrochloride","5-ALA hydrochloride","Cl.NCC(=O)CCC(O)=O",-3.318,2,1,4]
["S2554","Daphnetin","e11","L1300-09","in 10mM DMSO","CFDA",null,null,"Cardiovascular Disease","EGFR,PKA,PKC","Angiogenesis","Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor, inhibits EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively, also known to exhibit anti-inflammatory and anti-oxidant activities.",178.14,"486-35-1",35,196.47,"<1",0,"http://selleckchem.com/products/Daphnetin.html","C9H6O4","free base","N/A","OC1=CC=C2C=CC(=O)OC2=C1O",1.415,2,2,0]
["S2555","Clarithromycin","f11","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.4;KP Ⅹ;JP17;IP2010;CP2005;Martindale:The Extra Pharmacopoeia","065136,065137,065144,065145,065154,065155,065174,065178,065195,065210,065250,065266,065283,065382,065384,065489,202532,202710,203243,203584,206714,208987","Infection","P450 (e.g. CYP17)","Metabolism","Clarithromycin (A-56268) is a macrolide antibiotic and a CYP3A4 inhibitor, used to treat a number of bacterial infections.",747.95,"81103-11-9",25,33.42,"<1",0,"http://selleckchem.com/products/clarithromycin.html","C38H69NO13","free base","A-56268","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(CC(C)C(=O)C(C)C(O)C1(C)O)OC",2.2,9,3,8]
["S2556","Rosiglitazone (BRL 49653)","g11","L1300-09","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","USP42-NF37;IP2010;Martindale:The Extra Pharmacopoeia","076748,078023","Endocrinology/Metabolic Disease","Autophagy,Ferroptosis,PPAR,TRP Channel","Metabolism","Rosiglitazone (BRL 49653) is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively. Rosiglitazone is a pure ligand of PPAR-gamma, and has no PPAR-alpha-binding action. Rosiglitazone modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis.",357.43,"122320-73-4",71,198.64,"<1",0,"http://selleckchem.com/products/Rosiglitazone-Avandia.html","C18H19N3O3S","Free Base","BRL 49653","CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C3=CC=CC=N3",3.268,4,1,7]
["S2557","Terbinafine HCl","h11","L1300-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","076377,076390,076713,077065,077136,077137,077195,077223,077511,077533,077714,077919,078157,078163,078199,078229,078297","Infection","Fungal","Microbiology","Terbinafine HCl (KWD 201,KWD 2019,TDT 067 hydrochloride) inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug.",327.89,"78628-80-5",66,201.29,"<1",0,"http://selleckchem.com/products/Terbinafine-hydrochloride-Lamisil.html","C21H25N.HCl","Hydrochloride","KWD 201,KWD 2019,TDT 067 hydrochloride","Cl.CN(C\\C=C\\C#CC(C)(C)C)CC1=CC=CC2=C1C=CC=C2",5.717,0,0,6]
["S2559","Cortisone acetate","a2","L1300-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","BP2015;USP38-NF33;BP2013 ;IP2010;CP2005;Martindale:The Extra Pharmacopoeia","008126,008284,009458,080333,080341,080493,080630,080694,080731,080776,080836,083147,083471,083536,084246,085677,085736,085884","Immunology/Inflammation/Endocrinology","Glucocorticoid Receptor","Endocrinology & Hormones","Cortisone acetate (Cortone, NSC 49420) is an acetate salt form of cortisone that is a steroid hormone and a glucocorticoid.",402.48,"50-04-4",7,17.39,"<1",0,"http://selleckchem.com/products/Cortisone-acetate-Cortone.html","C23H30O6","free base","Cortone,NSC 49420","CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3C(=O)CC12C",1.619,5,0,4]
["S2561","Clomifene citrate","b2","L1300-10","in 10mM DMSO","CFDA,PMDA","BP2019 ;EP9.5;KP Ⅹ ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia",null,"Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Clomifene citrate (NSC 35770, Clomiphene citrate) is a selective estrogen receptor modulator, used in the treatment of ovulation induction.",598.08,"50-41-9",120,200.64,"<1",0,"http://selleckchem.com/products/Clomifene-citrate-Serophene.html","C26H28ClNO.C6H8O7","Citrate","NSC 35770, Clomiphene citrate","CCN(CC)CCOC1=CC=C(C=C1)C(=C(Cl)/C2=CC=CC=C2)/C3=CC=CC=C3.OC(=O)CC(O)(CC(O)=O)C(O)=O",2.129,4,0,14]
["S2564","Cloxacillin Sodium","c2","L1300-10","in 10mM DMSO","FDA,DMF,CFDA,HMA","BP2019 ;EP9.2;KP Ⅹ ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","061452,062240,062268,062978","Infection","Anti-infection","Microbiology","Cloxacillin Sodium(Cloxacap,BRL 1621 sodium salt) is a sodium salt of cloxacillin that is a penicillinase-resistant, acid resistant, semi-synthetic penicillin.",475.88,"7081-44-9",55,115.58,55,115.58,"http://selleckchem.com/products/Cloxacillin-sodium-Cloxacap.html","C19H19ClN3NaO6S","Sodium Salt & hydrate","Cloxacap,BRL 1621 sodium salt","O.[Na+].CC1=C(C(=O)NC2C3SC(C)(C)C(N3C2=O)C([O-])=O)C(=NO1)C4=CC=CC=C4Cl",0.619,4,1,4]
["S2565","Amoxicillin Sodium","d2","L1300-10","in 10mM DMSO","DMF,CFDA,HMA","BP2019;EP9.2;KP Ⅹ;IP2010;CP2005;Martindale:The Extra Pharmacopoeia",null,"Infection","Antibiotics,Bacterial","Microbiology","Amoxicillin Sodium (Clavulanate,Amoxycillin sodium) is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.",387.39,"34642-77-8",78,201.35,78,201.35,"http://selleckchem.com/products/amoxicillin-amox.html","C16H18N3O5S.Na","Sodium Salt","Clavulanate,Amoxycillin sodium","[Na+].CC1(C)SC2C(NC(=O)C(N)C3=CC=C(O)C=C3)C(=O)N2C1C([O-])=O",-1.534,2,3,4]
["S2566","Isoprenaline (NCI-C55630) HCl","e2","L1300-10","in 10mM DMSO","DMF,CFDA","BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Isoprenaline HCl (NCI-c55630,Isoproterenol hydrochloride) is a non-selective beta-adrenergic receptor agonist, used for the treatment of bradycardia and heart block.",247.72,"51-30-9",50,201.84,50,201.84,"http://selleckchem.com/products/Isoprenaline-hydrochloride.html","C11H17NO3.HCl","Hydrochloride","NCI-c55630,Isoproterenol hydrochloride","Cl.CC(C)NCC(O)C1=CC=C(O)C(=C1)O",1.481,0,4,4]
["S2567","Medroxyprogesterone acetate (NSC-26386)","f2","L1300-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","040159,040311,076552,076553,077235,077334,078711,088484,210227,210335,210760,210761","Cancer/Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Medroxyprogesterone acetate (MPA, NSC-26386, Medroxyprogesterone 17-acetate, Farlutin) is a synthetic progestin and act as a potent progesterone receptor agonist, used to treat abnormal menstruation or irregular vaginal bleeding.",386.52,"71-58-9",12,31.05,"<1",0,"http://selleckchem.com/products/Medroxyprogesterone-acetate.html","C24H34O4","Free Base","MPA, NSC-26386, Medroxyprogesterone 17-acetate, Farlutin","CC1CC2C(CCC3(C)C2CCC3(OC(C)=O)C(C)=O)C4(C)CCC(=O)C=C14",3.755,4,0,3]
["S2569","Phenylephrine (NCI-C55641) HCl","g2","L1300-10","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","203510,203826,207926,208905,210025,210333,210334,210665,210666,211078,211079","Cardiovascular Disease","Adrenergic Receptor","GPCR & G Protein","Phenylephrine HCl (NCI-c55641,Phenylephrine hydrochloride,(R)-(-)-Phenylephrine hydrochloride, L-Phenylephrine hydrochloride) is a selective α1-adrenergic receptor agonist, used primarily as a decongestant.",203.67,"61-76-7",41,201.31,41,201.31,"http://selleckchem.com/products/Phenylephrine-hydrochloride.html","C9H13NO2.HCl","Hydrochloride","NCI-c55641,Phenylephrine hydrochloride,(R)-(-)-Phenylephrine hydrochloride, L-Phenylephrine hydrochloride","Cl.CNCC(O)C1=CC(=CC=C1)O",0.997,0,3,3]
["S2570","Prednisolone Acetate","h2","L1300-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37 ;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;BP2016;IP2010;Martindale:The Extra Pharmacopoeia","083032,083398,083654,083738,083764,083767,084492,084717,085781","Endocrinology/Hematology/Immunology/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Prednisolone Acetate (Omnipred,Prednisolone-21-acetate) is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant agent.",402.48,"52-21-1",81,201.25,"<1",0,"http://selleckchem.com/products/Prednisolone-acetate-Omnipred.html","C23H30O6","free base","Omnipred,Prednisolone-21-acetate","CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)C=CC4(C)C3C(O)CC12C",1.639,4,1,4]
["S2573","Tetracaine HCl","a3","L1300-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","208135,210821","Neurological Disease","Calcium Channel","Transmembrane Transporters","Tetracaine HCl (Amethocaine hydrochloride) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.",300.82,"136-47-0",60,199.45,60,199.45,"http://selleckchem.com/products/tetracaine-hydrochloride-pontocaine.html","C15H24N2O2.HCl","Hydrochloride","Amethocaine hydrochloride","Cl.CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C",3.343,2,1,9]
["S2574","Tetracycline HCl","b3","L1300-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","BP2013;IP2010 ;Martindale:The Extra Pharmacopoeia","060059,060173,060174,060290,060291,060446,060469,060471,060633,060704,060736,060768,060783,061148,061214,061471,061685,061802,061837,062085,062103,062300,062343,062540,062686,062752,210662,210674","Infection","Antibiotics,Antibiotics for Mammalian Cell Culture,Selection Antibiotics for Transfected Cell","Microbiology","Tetracycline HCl (NCI-c55561) is a hydrochloride salt of tetracycline that is a broad-spectrum polyketide antibiotic.",480.9,"64-75-5",96,199.63,96,199.63,"http://selleckchem.com/products/tetracycline-hydrochloride.html","C22H24N2O8.HCl","Hydrochloride","NCI-c55561","Cl.CN(C)C1C2CC3C(=C(O)C2(O)C(=O)C(=C1O)C(N)=O)C(=O)C4=C(O)C=CC=C4C3(C)O",-0.513,3,4,2]
["S2576","Xylometazoline HCl","c3","L1300-10","in 10mM DMSO","DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia",null,"Immunology/Inflammation","Adrenergic Receptor","GPCR & G Protein","Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM.",280.84,"1218-35-5",27,96.14,56,199.4,"http://selleckchem.com/products/xylometazoline-hcl.html","C16H24N2.HCl","HCl","N/A","Cl.CC1=C(CC2=NCCN2)C(=CC(=C1)C(C)(C)C)C",3.906,1,1,3]
["S2577","Phenacetin","d3","L1300-10","in 10mM DMSO","DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;IP2010;Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","COX","Neuronal Signaling","Phenacetin (Acetophenetidin) is a non-opioid analgesic without anti-inflammatory properties.",179.22,"62-44-2",36,200.87,"<1",0,"http://selleckchem.com/products/phenacetin.html","C10H13NO2","free base","Acetophenetidin","CCOC1=CC=C(NC(C)=O)C=C1",1.282,2,1,3]
["S2579","Zidovudine","e3","L1300-10","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","022294,074047,076844,077267,077268,077327,077981,078128,078349,078922,090092,090561,091457,200732,202058,204538","Infection","CRISPR/Cas9,Reverse Transcriptase","Microbiology","Zidovudine (ZDV, Azidothymidine, NSC 602670,Retrovir) is a nucleoside analogue reverse transcriptase inhibitor, used to treat HIV. It could decrease the HDR efficiency and decrease CRISPR-mediated sequence-specific genome knockin events while increaseing knockout efficiency.",267.24,"30516-87-1",53,198.32,53,198.32,"http://selleckchem.com/products/zidovudine-retrovir.html","C10H13N5O4","free base","Azidothymidine, NSC 602670,Retrovir","CC1=CN(C2CC(N=[N+]=[N-])C(CO)O2)C(=O)NC1=O",0.064,4,2,3]
["S2581","Quinapril HCl","f3","L1300-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","075504,076036,076049,076240,076459,076607,076694,076803,077690,078457,090800,202725,205823","Cardiovascular Disease","RAAS","Endocrinology & Hormones","Quinapril HCl (CI-906, PD-109452-2) is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM.",474.98,"82586-55-8",18,37.9,95,200.01,"http://selleckchem.com/products/quinapril-hydrochloride-accupril.html","C25H30N2O5.HCl","Hydrochloride","CI-906, PD-109452-2","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=C(CC2C(O)=O)C=CC=C3",1.038,4,1,10]
["S2583","Thiamphenicol","g3","L1300-10","in 10mM DMSO","DMF,CFDA","BP2019;EP9.2;KP Ⅹ;Martindale:The Extra Pharmacopoeia",null,"Infection","Antibiotics","Microbiology","Thiamphenicol (Thiophenicol,Dextrosulphenidol) is an antimicrobial antibiotic and a methyl-sulfonyl analogue of chloramphenicol.",356.22,"15318-45-3",71,199.32,"<1",0,"http://selleckchem.com/products/thiamphenicol-thiophenicol.html","C12H15Cl2NO5S","free base","Thiophenicol,Dextrosulphenidol","C[S](=O)(=O)C1=CC=C(C=C1)C(O)C(CO)NC(=O)C(Cl)Cl",0.657,3,3,6]
["S2584","Clobetasol propionate","h3","L1300-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","074087,074089,074128,074139,074248,074249,074331,074392,074407,075027,075057,075205,075224,075279,075338,075363,075368,075391,076977,077763,078223,078854,090898,090974,200302,201402,206075,206378,206805,207218,208125,208589,208667,208779,208841,208842,208881,208933,209004,209095,209147,209361,209701,209871,209974,210034,210190,210199,210208,210446,210551,210809,211074,211256,211348,211401,211800","Immunology/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Clobetasol propionate (CGP9555, CCl 4725) is an anti-inflammatory corticosteroid used to treat various skin disorders.",466.97,"25122-46-7",93,199.16,"<1",0,"http://selleckchem.com/products/clobetasol-propionate.html","C25H32ClFO5","free base","CGP9555, CCl 4725","CCC(=O)OC1(C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)CCl",3.958,4,1,5]
["S2585","Brompheniramine hydrogen maleate","a4","L1300-10","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","083123,083215,083820,083821,084351,084468,085466,085521,085592,085769,085850,085888,086187,086936,086987,087009,087517,087964,088604","Immunology","Histamine Receptor","Neuronal Signaling","Brompheniramine hydrogen maleate(Brompheniramine maleate) is a histamine H1 receptors antagonist.",435.31,"980-71-2",87,199.86,46,105.67,"http://selleckchem.com/products/brompheniramine.html","C16H19BrN2.C4H4","Maleate","Brompheniramine maleate","CN(C)CCC(C1=CC=C(Br)C=C1)C2=CC=CC=N2.OC(=O)\\C=C/C(O)=O",0.784,3,0,7]
["S2586","Dimethyl Fumarate","b4","L1300-10","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","210226,210285,210291,210305,210382,210385,210390,210402,210440,210460,210492,210499,210500,210538","Immunology/Inflammation","Nrf2","Immunology & Inflammation","Dimethyl fumarate (DMF,Tecfidera,BG-12) is the methyl ester of fumaric acid, used to treat people with relapsing forms of multiple sclerosis. Dimethyl fumarate is a nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator and induces upregulation of antioxidant gene expression.",144.13,"624-49-7",29,201.21,"<1",0,"http://selleckchem.com/products/dimethyl-Fumarate.html","C6H8O4","free base","DMF,Tecfidera,BG-12","COC(=O)\\C=C\\C(=O)OC",0.49,4,0,4]
["S2589","Miglitol","c4","L1300-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","JP17;Martindale:The Extra Pharmacopoeia","203965","Endocrinology/Metabolic Disease","Carbohydrate Metabolism","Metabolism","Miglitol (BAY-M-1099,Glyset) is an oral anti-diabetic drug.",207.22,"72432-03-2",3,14.48,"<1",0,"http://selleckchem.com/products/miglitol-glyset.html","C8H17NO5","free base","BAY-M-1099,Glyset","OCCN1CC(O)C(O)C(O)C1CO",-2.444,0,5,3]
["S2590","Pioglitazone (AD-4833)","d4","L1300-10","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","076799","Endocrinology/Metabolic Disease","PPAR","Metabolism","Pioglitazone (AD-4833, U 72107) is a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, used to treat diabetes; A weak activator for full-length hPPARα, but not full-length hPPARδ.",356.44,"111025-46-8",10,28.06,"<1",0,"https://www.selleckchem.com/products/pioglitazone.html","C19H20N2O3S","Free Base","U 72107","CCC1=CC=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)N=C1",3.907,4,1,7]
["S2593","Tolvaptan","e4","L1300-10","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","022275","Cardiovascular Disease","Vasopressin Receptor","GPCR & G Protein","Tolvaptan (OPC-41061) is an orally effective nonpeptide arginine vasopressin V2 receptor antagonist with IC50 of 3 nM, used to treat hyponatremia.",448.94,"150683-30-0",89,198.24,"<1",0,"http://selleckchem.com/products/tolvaptan-opc-41061.html","C26H25ClN2O3","free base","OPC-41061","CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(O)C4=C3C=CC(=C4)Cl)C",5.127,2,2,3]
["S2594","Pramiracetam","f4","L1300-10","in 10mM DMSO","marketed in Italy","Martindale:The Extra Pharmacopoeia",null,"Angiology/Neurological Disease","Others","Others","Pramiracetam (CI-879,Pramistar) is a more potent nootropic drug derived from piracetam.",269.38,"68497-62-1",54,200.46,"<1",0,"http://selleckchem.com/products/pramiracetam.html","C14H27N3O2","free base","CI-879,Pramistar","CC(C)N(CCNC(=O)CN1CCCC1=O)C(C)C",0.486,2,1,7]
["S2596","Clindamycin palmitate HCl","g4","L1300-10","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;EP9.3;BP2019;KP Ⅹ;JP17;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","090902,201821,202409,203063,203513,206958,207047","Infection/Parasitology","Bacterial","Microbiology","Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic.",699.85,"25507-04-4",140,200.04,140,200.04,"http://selleckchem.com/products/clindamycin-palmitate-hcl.html","C34H63ClN2O6S.HCl","Hydrochloride","N/A","Cl.CCCCCCCCCCCCCCCC(=O)OC1C(O)C(O)C(OC1SC)C(NC(=O)C2CC(CCC)CN2C)C(C)Cl",8.635,4,3,23]
["S2599","L-Thyroxine","h4","L1300-10","in 10mM DMSO",null,"USP42-NF37;IP2010",null,"Endocrinology","THR","Metabolism","L-Thyroxine (NSC 36397,Levothyroxine) is a synthetic form of thyroxine and a hormone replacement drug.",776.87,"51-48-9",100,128.72,"<1",0,"http://selleckchem.com/products/l-thyroxine.html","C15H11I4NO4","free base","NSC 36397,Levothyroxine","NC(CC1=CC(=C(OC2=CC(=C(O)C(=C2)I)I)C(=C1)I)I)C(O)=O",2.026,2,2,5]
["S2601","Gliclazide","a5","L1300-10","in 10mM DMSO","DMF,CFDA,PMDA,HMA","BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia",null,"Endocrinology/Metabolic Disease","Potassium Channel","Transmembrane Transporters","Gliclazide(S1702, SE1702)  is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM.",323.41,"21187-98-4",65,200.98,"<1",0,"http://selleckchem.com/products/gliclazide-diamicron.html","C15H21N3O3S","free base","S1702, SE1702","CC1=CC=C(C=C1)[S](=O)(=O)NC(=O)NN2CC3CCCC3C2",1.905,3,2,3]
["S2602","Acemetacin","b5","L1300-10","in 10mM DMSO","DMF,CFDA,PMDA,HMA","BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia",null,"Immunology/Inflammation","COX","Neuronal Signaling","Acemetacin (K-708,TVX 1322) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.",415.82,"53164-05-9",83,199.61,"<1",0,"http://selleckchem.com/products/acemetacin-emflex.html","C21H18ClNO6","free base","K-708,TVX 1322","COC1=CC2=C(C=C1)[N](C(=C2CC(=O)OCC(O)=O)C)C(=O)C3=CC=C(Cl)C=C3",3.942,5,0,7]
["S2603","Tioxolone","c5","L1300-10","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Inflammation","Carbonic Anhydrase","Metabolism","Tioxolone(Thioxolone) is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM.",168.17,"4991-65-5",34,202.18,"<1",0,"http://selleckchem.com/products/tioxolone.html","C7H4O3S","free base","Thioxolone","OC1=CC=C2SC(=O)OC2=C1",2.303,2,1,0]
["S2605","Idebenone","d5","L1300-10","in 10mM DMSO","DMF,EMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","ROS","Immunology & Inflammation","Idebenone (CV-2619) is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant.",338.44,"58186-27-9",68,200.92,"<1",0,"http://selleckchem.com/products/idebenone.html","C19H30O5","free base","CV-2619","COC1=C(OC)C(=O)C(=C(C)C1=O)CCCCCCCCCCO",3.836,4,1,12]
["S2606","Mifepristone (RU486)","e5","L1300-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","IP2010 ;Martindale:The Extra Pharmacopoeia","091178,211436","Endocrinology/Metabolic Disease","Apoptosis related,Autophagy,Bcl-2,Estrogen/progestogen Receptor,Glucocorticoid Receptor","Endocrinology & Hormones","Mifepristone (RU486, C-1073, RU 38486, Mifegyne) is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.",429.59,"84371-65-3",85,197.86,"<1",0,"http://selleckchem.com/products/Mifepristone(Mifeprex).html","C29H35NO2","free base","RU486, C-1073, RU 38486, RU-486, Mifegyne","CC#CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C(CC12C)C5=CC=C(C=C5)N(C)C",5.655,1,0,3]
["S2607","Buflomedil HCl","f5","L1300-10","in 10mM DMSO","DMF","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Angiology/Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Buflomedil HCl(NSC 759291) is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease;  A nonselective alpha adrenergic receptor inhibitor.",343.85,"35543-24-9",31,90.16,69,200.67,"http://selleckchem.com/products/auflomedil-hcl.html","C17H25NO4.HCl","Hydrochloride","NSC 759291","Cl.COC1=CC(=C(C(=O)CCCN2CCCC2)C(=C1)OC)OC",2.939,4,0,8]
["S2608","Fluocinonide","g5","L1300-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","017373,019117,071500,071535,071790,072488,072511,072522,072537,072857,072933,072934,073030,073085,073481,074799,074905,074935,075008,090256,091282,200734,200735,206003,207538,207554,207680,208948,209030,209118,209283,209699,210554,211111,211410,211758","Immunology/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Fluocinonide (Vanos,nsc 101791) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema.",494.52,"356-12-7",99,200.19,"<1",0,"http://selleckchem.com/products/Fluocinonide(Vanos).html","C26H32F2O7","free base","Vanos,nsc 101791","CC(=O)OCC(=O)C12OC(C)(C)OC1CC3C4CC(F)C5=CC(=O)C=CC5(C)C4(F)C(O)CC23C",1.374,6,1,4]
["S2609","Inulin","h5","L1300-10","in 10mM DMSO","FDA,DMF,PMDA","USP42-NF37;BP2010;Martindale:The Extra Pharmacopoeia","002282","Endocrinology/Metabolic Disease","Others","Others","Inulin(Inulin and sodium chloride), a starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan.","N/A","9005-80-5",10,10,104,0,"http://selleckchem.com/products/inulin.html","C6nH10n+2O5n+1","Free Base","N/A","OCC1OC(OC2(CO)OC(CO)C(O)C2O)C(O)C(O)C1O",-3.577,3,8,5]
["S2610","Lonidamine (AF-1890)","a6","L1300-10","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Cancer","Carbohydrate Metabolism,Others","Metabolism","Lonidamine (AF 1890, Diclondazolic Acid, DICA) is an orally administered small molecule hexokinase inactivator.",321.16,"50264-69-2",64,199.28,"<1",0,"http://selleckchem.com/products/lonidamine.html","C15H10Cl2N2O2","free base","Diclondazolic Acid, DICA","OC(=O)C1=N[N](CC2=C(Cl)C=C(Cl)C=C2)C3=CC=CC=C13",4.65,2,0,3]
["S2611","Ethisterone","b6","L1300-10","in 10mM DMSO","CFDA",null,null,"Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Ethisterone(17α-Ethynyltestosterone) is a progestogen hormone being considered to treat prostate cancer.",312.45,"434-03-7",4,12.8,"<1",0,"http://www.selleck.cn/products/ethisterone.html","C21H28O2","Free Base","17α-Ethynyltestosterone","CC12CCC(=O)C=C1CCC3C2CCC4(C)C3CCC4(O)C#C",4.521,1,0,0]
["S2613","Clorsulon","c6","L1300-10","in 10mM DMSO","DMF","USP42-NF37;Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","Anti-infection","Microbiology","Clorsulon (MK-401,L631529) is used in the treatment of Fasciola hepatica infections in calves and sheep.",380.66,"60200-06-8",76,199.65,"<1",0,"http://selleckchem.com/products/clorsulon.html","C8H8Cl3N3O4S2","free base","MK-401,L631529","NC1=CC(=C(C=C1[S](N)(=O)=O)[S](N)(=O)=O)C(Cl)=C(Cl)Cl",0.155,4,3,3]
["S2614","Arecoline HBr","d6","L1300-10","in 10mM DMSO","DMF",null,null,"Neurological Disease/Ophthalmology/Parasitology","AChR","Neuronal Signaling","Arecoline(NSC-31750) is a muscarinic acetylcholine receptor agonist.",236.11,"300-08-3",47,199.06,47,199.06,"https://www.selleckchem.com/products/arecoline-hbr.html","C8H13NO2.HBr","HBr","NSC-31750","Br.COC(=O)C1=CCCN(C)C1",1.234,2,0,2]
["S2615","Noradrenaline bitartrate monohydrate","e6","L1300-10","in 10mM DMSO","CFDA","IP2010",null,"Angiology/Cardiovascular Disease/Neurological Disease","Adrenergic Receptor","GPCR & G Protein","Noradrenaline bitartrate monohydrate (Levophed) is a direct alpha-adrenergic receptors stimulator.",337.28,"108341-18-0",64,189.75,64,189.75,"http://selleckchem.com/products/noradrenaline-bitartrate-monohydrate-levophed.html","C8H11NO3.C4H6O6.H2O","bitartrate monohydrate","Levophed","O.NCC(O)C1=CC(=C(O)C=C1)O.OC(C(O)C(O)=O)C(O)=O",-4.409,2,6,5]
["S2625","Fostamatinib (R788)","f6","L1300-10","in 10mM DMSO","FDA,NDC",null,"209299","Immunology","Syk","Angiogenesis","Fostamatinib (R788), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.",580.46,"901119-35-5",116,199.84,"<1",0,"http://selleckchem.com/products/R7935788-Fostamatinib.html","C23H26FN6O9P","free base","N/A","COC1=C(OC)C(=CC(=C1)NC2=NC=C(F)C(=N2)NC3=CC=C4OC(C)(C)C(=O)N(CO[P](O)(O)=O)C4=N3)OC",3.458,9,2,10]
["S2664","Clinofibrate","g6","L1300-10","in 10mM DMSO","PMDA","KP Ⅹ ;JP17;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","HMG-CoA Reductase","Metabolism","Clinofibrate inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR) with IC50 of 0.47 mM, is a lipid-lowering agent used for controlling high cholesterol and triacylglyceride levels in the blood.",468.58,"30299-08-2",94,200.61,"<1",0,"http://selleckchem.com/products/clinofibrate.html","C28H36O6","free base","N/A","CCC(C)(OC1=CC=C(C=C1)C2(CCCCC2)C3=CC=C(OC(C)(CC)C(O)=O)C=C3)C(O)=O",6.829,4,0,10]
["S2665","Ciprofibrate","h6","L1300-10","in 10mM DMSO","HMA","BP2019;EP9.2;CP2005;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","PPAR","DNA Damage/DNA Repair","Ciprofibrate (Win-35833) is a peroxisome proliferator-activated receptor agonist.",289.15,"52214-84-3",58,200.59,"<1",0,"http://selleckchem.com/products/ciprofibrate.html","C13H14Cl2O3","free base","Win-35833","CC(C)(OC1=CC=C(C=C1)C2CC2(Cl)Cl)C(O)=O",2.954,2,0,4]
["S2667","Dolutegravir (GSK1349572)","a7","L1300-10","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"208355,209602,209658,210963","Infection","Integrase","Microbiology","Dolutegravir (GSK1349572,S/GSK1349572,Tivicay) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM in a cell-free assay, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.",419.38,"1051375-16-6",83,197.91,"<1",0,"http://selleckchem.com/products/s-gsk1349572.html","C20H19F2N3O5","free base","GSK1349572,S/GSK1349572,Tivicay","CC1CCOC2CN3C=C(C(=O)NCC4=C(F)C=C(F)C=C4)C(=O)C(=C3C(=O)N12)O",0.3,4,2,3]
["S2673","Trametinib (GSK1120212)","b7","L1300-10","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"204114","Cancer","Apoptosis related,Autophagy,MEK","MAPK","Trametinib (GSK1120212, JTP-74057, Mekinist) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. Trametinib activates autophagy and induces apoptosis.",615.39,"871700-17-3",22,35.75,"<1",0,"http://selleckchem.com/products/gsk1120212-jtp-74057.html","C26H23FIN5O4","free base","JTP-74057, Mekinist","CN1C(=O)C(=C2N(C(=O)N(C3CC3)C(=O)C2=C1NC4=CC=C(I)C=C4F)C5=CC(=CC=C5)NC(C)=O)C",3.176,4,2,5]
["S2680","Ibrutinib (PCI-32765)","c7","L1300-10","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"205552,210563","Cancer/Hematology","BTK,Target Protein Ligand","Angiogenesis","Ibrutinib (PCI-32765,Imbruvica) is a potent and highly selective Brutons tyrosine kinase (Btk) inhibitor with IC50 of 0.5 nM in cell-free assays, modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc. Ibrutinib is applicable as a Btk ligand in the synthesis of a series of PROTACs including P13I.",440.5,"936563-96-1",88,199.77,"<1",0,"http://selleckchem.com/products/pci-32765.html","C25H24N6O2","free base","PCI-32765,Imbruvica","NC1=C2C(=NC=N1)[N](N=C2C3=CC=C(OC4=CC=CC=C4)C=C3)C5CCCN(C5)C(=O)C=C",3.985,5,1,5]
["S2700","Tirbanibulin","d7","L1300-10","in 10mM DMSO","FDA; EMA; NDC; DMF",null,213189,"Cancer","Src","Angiogenesis","Tirbanibulin(KX2-391,KX 01), the first clinical Src inhibitor (peptidomimetic class) that targets the peptide substrate site of Src, with GI50 of 9-60 nM in cancer cell lines. Phase 2.",431.53,"897016-82-9",86,199.29,"<1",0,"http://selleckchem.com/products/kx2-391.html","C26H29N3O3","free base","KX2-391,KX 01","O=C(CC1=CC=C(C=N1)C2=CC=C(OCCN3CCOCC3)C=C2)NCC4=CC=CC=C4",3.262,4,1,9]
["S2721","Nilvadipine","e7","L1300-10","in 10mM DMSO","DMF,PMDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Nilvadipine (ARC029, FR34235,FK235) is a potent calcium channel blocker with an IC50 of 0.03 nM.",385.37,"75530-68-6",77,199.81,"<1",0,"http://selleckchem.com/products/nilvadipine-arc029.html","C19H19N3O6","free base","ARC029, FR34235,FK235","COC(=O)C1=C(NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OC(C)C)C)C#N",2.087,4,1,7]
["S2727","Dacomitinib (PF-00299804)","f7","L1300-10","in 10mM DMSO","FDA,NDC",null,"211288","Cancer/Respiratory Disease","Apoptosis related,EGFR,HER2","Protein Tyrosine Kinase","Dacomitinib (PF299804, PF299) is a potent, irreversible pan-ErbB inhibitor, mostly to EGFR with IC50 of 6 nM in a cell-free assay. Dacomitinib inhibits ERBB2 and ERBB4 with IC50 of 45.7 nM and 73.7 nM, respectively. Dacomitinib is effective against NSCLCs with EGFR or ERBB2 mutations (resistant to gefitinib) as well as those harboring the EGFR T790M mutation. Dacomitinib inhibits cell growth and induces apoptosis. Phase 2.",469.94,"1110813-31-4",19,40.43,"<1",0,"http://selleckchem.com/products/pf299804.html","C24H25ClFN5O2","free base","PF299804,PF299","COC1=C(NC(=O)/C=C/CN2CCCCC2)C=C3C(=NC=NC3=C1)NC4=CC(=C(F)C=C4)Cl",5.055,4,2,7]
["S2736","Fedratinib (TG101348)","g7","L1300-10","in 10mM DMSO","FDA,NDC",null,"212327","Hematology","Apoptosis related,c-RET,FLT3,JAK","JAK/STAT","Fedratinib (SAR302503, TG101348) is a selective inhibitor of JAK2 with IC50 of 3 nM in cell-free assays, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3. Fedratinib also inhibits FMS-like tyrosine kinase 3 (FLT3) and RET (c-RET) with IC50 of 15 nM and 48 nM, respectively. Fedratinib has potential antineoplastic activity. Fedratinib inhibits proliferation and induces apoptosis. Phase 2.",524.68,"936091-26-8",100,190.59,"<1",0,"http://selleckchem.com/products/Fedratinib-SAR302503-TG101348.html","C27H36N6O3S","free base","SAR302503","CC1=C(NC2=CC=CC(=C2)[S](=O)(=O)NC(C)(C)C)N=C(NC3=CC=C(OCCN4CCCC4)C=C3)N=C1",5.123,5,3,11]
["S2741","Niraparib (MK-4827)","h7","L1300-10","in 10mM DMSO","FDA,EMA,NDC",null,"208447","Cancer","Apoptosis related,PARP","DNA Damage/DNA Repair","Niraparib (MK-4827) is a selective inhibitor of PARP1/2 with IC50 of 3.8 nM/2.1 nM, with great activity in cancer cells with mutant BRCA-1 and BRCA-2. It is >330-fold selective against PARP3, V-PARP and Tank1. Niraparib can form PARP–DNA complexes resulting in DNA damage, apoptosis, and cell death. Phase 3.",320.39,"1038915-60-4",64,199.76,"<1",0,"http://selleckchem.com/products/mk-4827.html","C19H20N4O","Free Base",0,"NC(=O)C1=CC=CC2=C[N](N=C12)C3=CC=C(C=C3)C4CCCNC4",2.618,2,2,3]
["S2760","Canagliflozin (JNJ 28431754)","a8","L1300-10","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"204042","Endocrinology/Metabolic Disease","SGLT","GPCR & G Protein","Canagliflozin (TA 7284, JNJ 28431754) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM in a cell-free assay, exhibits 413-fold selectivity over hSGLT1.",444.52,"842133-18-0",88,197.97,"<1",0,"http://selleckchem.com/products/canagliflozin.html","C24H25FO5S","free base","TA 7284","CC1=C(CC2=CC=C(S2)C3=CC=C(F)C=C3)C=C(C=C1)C4OC(CO)C(O)C(O)C4O",3.446,1,4,5]
["S2762","Alectinib (CH5424802)","b8","L1300-10","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"208434","Cancer/Respiratory Disease","ALK","Protein Tyrosine Kinase","Alectinib (CH5424802, AF-802, RG-7853) is a potent ALK inhibitor with IC50 of 1.9 nM in cell-free assays, sensitive to L1196M mutation and higher selectivity for ALK than PF-02341066, NVP-TAE684 and PHA-E429.",482.62,"1256580-46-7",6,12.43,1,2.07,"http://www.selleckchem.com/products/ch5424802.html","C30H34N4O2","Free Base","AF-802, RG-7853,CH5424802","CCC1=CC2=C(C=C1N3CCC(CC3)N4CCOCC4)C(C)(C)C5=C(C2=O)C6=CC=C(C=C6[NH]5)C#N",5.203,2,1,3]
["S2765","MK-2048","c8","L1300-10","in 10mM DMSO","DMF",null,null,"Infection","Integrase","Microbiology","MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.",461.87,"869901-69-9",9,19.49,"<1",0,"http://selleckchem.com/products/mk-2048.html","C21H21ClFN5O4","free base","N/A","CCN1CC(C)[N]2C(=C(O)C3=C2C(=NN(CC4=CC=C(F)C(=C4)Cl)C3=O)C(=O)NC)C1=O",2.446,4,2,4]
["S2787","Laquinimod","d8","L1300-10","in 10mM DMSO","EMA",null,null,"Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Laquinimod (ABR-215062, LAQ) is a potent immunomodulator. Phase 3.",356.8,"248281-84-7",61,170.96,"<1",0,"http://selleckchem.com/products/laquinimod-abr-215062.html","C19H17ClN2O3","free base","ABR-215062, LAQ","CCN(C(=O)C1=C(O)C2=C(C=CC=C2Cl)N(C)C1=O)C3=CC=CC=C3",2.884,2,1,3]
["S2789","Tofacitinib (CP-690550)","e8","L1300-10","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"209738,209790,209923","Immunology/Inflammation","Apoptosis related,JAK","JAK/STAT","Tofacitinib (CP-690550,Tasocitinib) is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1. Tofacitinib inhibits the expression of antiapoptotic BCL-A1 and BCL-XL in human plasmacytoid dendritic cells (PDC) and induced PDC apoptosis.",312.37,"477600-75-2",62,198.48,"<1",0,"http://selleckchem.com/products/tofacitinib-cp-690550.html","C16H20N6O","free base","Tasocitinib","CC1CCN(CC1N(C)C2=C3C=C[NH]C3=NC=N2)C(=O)CC#N",1.512,3,1,3]
["S2790","Istradefylline","f8","L1300-10","in 10mM DMSO","DMF,PMDA",null,null,"Neurological Disease","Adenosine Receptor","GPCR & G Protein","Istradefylline (KW-6002) is a selective adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. Phase 3.",384.43,"155270-99-8",6,15.61,"<1",0,"http://selleckchem.com/products/istradefylline-kw-6002.html","C20H24N4O4","free base","KW-6002","CCN1C(=O)N(CC)C2=C([N](C)C(=N2)\\C=C\\C3=CC=C(OC)C(=C3)OC)C1=O",2.957,5,0,6]
["S2792","Torcetrapib","g8","L1300-10","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","CETP","Metabolism","Torcetrapib (CP-529414) is a CETP inhibitor with IC50 of 37 nM, elevates HDL-C and reduces nonHDL-C in plasma. Phase 3.",600.47,"262352-17-0",120,199.84,"<1",0,"http://selleckchem.com/products/torcetrapib-cp-529414.html","C26H25F9N2O4","free base","CP-529414","CCOC(=O)N1C(CC)CC(N(CC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)C(=O)OC)C3=C1C=CC(=C3)C(F)(F)F",7.345,4,0,10]
["S2794","Sofosbuvir (GS-7977)","h8","L1300-10","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"204671","Infection","DNA/RNA Synthesis,HCV Protease","DNA Damage/DNA Repair","Sofosbuvir (PSI-7977, GS-7977) is a HCV NS5B polymerase inhibitor for the treatment of chronic hepatitis C virus (HCV) infection.",529.45,"1190307-88-0",100,188.88,11,20.78,"http://selleckchem.com/products/psi-7977-gs-7977.html","C22H29FN3O9P","free base","PSI-7977","CC(C)OC(=O)C(C)N[P](=O)(OCC1OC(N2C=CC(=O)NC2=O)C(C)(F)C1O)OC3=CC=CC=C3",0.921,7,3,11]
["S2797","Lonafarnib (SCH66336)","a9","L1300-10","in 10mM DMSO","FDA, NDC",null,null,"Others","Ras,Transferase","Metabolism","Lonafarnib (SCH66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM in cell-free assays, respectively. Phase 3.",638.82,"193275-84-2",127,198.8,"<1",0,"http://selleckchem.com/products/lonafarnib-sch66336.html","C27H31Br2ClN4O2","free base","SCH66336","NC(=O)N1CCC(CC1)CC(=O)N2CCC(CC2)C3C4=C(CCC5=C3C(=CC(=C5)Cl)Br)C=C(Br)C=N4",5.271,3,1,3]
["S2807","Dabrafenib (GSK2118436)","b9","L1300-10","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"202806","Cancer","Raf","MAPK","Dabrafenib (GSK2118436, GSK2118436A) is a mutant BRAFV600E specific inhibitor with IC50 of 0.7 nM in cell-free assays, with 7- and 9-fold less potency against B-Raf(wt) and c-Raf, respectively.",519.56,"1195765-45-7",30,57.74,"<1",0,"http://selleckchem.com/products/dabrafenib-gsk2118436.html","C23H20F3N5O2S2","free base","GSK2118436A","CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(F)C(=CC=C3)N[S](=O)(=O)C4=C(F)C=CC=C4F",5.377,5,2,6]
["S2809","MPEP","c9","L1300-10","in 10mM DMSO","DMF",null,null,"Cancer","GluR","Neuronal Signaling","MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.",193.24,"96206-92-7",39,201.82,"<1",0,"http://selleckchem.com/products/mpep.html","C14H11N","free base","N/A","CC1=NC(=CC=C1)C#CC2=CC=CC=C2",3.499,1,0,2]
["S2814","Alpelisib (BYL719)","d9","L1300-10","in 10mM DMSO","FDA",null,"212526","Cancer","PI3K","PI3K/Akt/mTOR","Alpelisib (BYL719) is a potent and selective PI3Kα inhibitor with IC50 of 5 nM in a cell-free assay, and minimal effect on PI3Kβ/γ/δ. Phase 2.",441.47,"1217486-61-7",88,199.33,"<1",0,"http://selleckchem.com/products/byl719.html","C19H22F3N5O2S","free base","N/A","CC1=C(SC(=N1)NC(=O)N2CCCC2C(N)=O)C3=CC(=NC=C3)C(C)(C)C(F)(F)F",2.826,4,2,5]
["S2830","Clindamycin","e9","L1300-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.3;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","063027,063029,063082,063083,065061,065194,065217,065242,065243,065442,091225,207402","Infection/Parasitology","Bacterial","Microbiology","Clindamycin inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.",424.98,"18323-44-9",85,200.01,"<1",0,"http://selleckchem.com/products/clindamycin.html","C18H33ClN2O5S","Free Base","N/A","CCCC1CC(N(C)C1)C(=O)NC(C(C)Cl)C2OC(SC)C(O)C(O)C2O",1.277,2,4,7]
["S2840","Apalutamide (ARN-509)","f9","L1300-10","in 10mM DMSO","FDA,EMA,NDC",null,"210951","Cancer","Androgen Receptor","Endocrinology & Hormones","Apalutamide (ARN-509) is a selective and competitive androgen receptor inhibitor with IC50 of 16 nM in a cell-free assay, useful for prostate cancer treatment. Phase 3.",477.43,"956104-40-8",18,37.7,"<1",0,"http://selleckchem.com/products/arn-509.html","C21H15F4N5O2S","free base","N/A","CNC(=O)C1=CC=C(C=C1F)N2C(=S)N(C(=O)C23CCC3)C4=CN=C(C#N)C(=C4)C(F)(F)F",4.452,3,1,4]
["S2851","Baricitinib (INCB028050)","g9","L1300-10","in 10mM DMSO","FDA,EMA,NDC,PMDA",null,"207924","Immunology/Inflammation","COVID-19,JAK","JAK/STAT","Baricitinib (LY3009104, INCB028050) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM in cell-free assays, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Baricitinib is found to reduce or interrupt the passage of the virus into target cells and is used in the treatment research for COVID-19. Phase 3.",371.42,"1187594-09-7",74,199.24,"<1",0,"http://selleckchem.com/products/baricitinib-ly3009104.html","C16H17N7O2S","free base","LY3009104","CC[S](=O)(=O)N1CC(CC#N)(C1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4",0.36,5,1,5]
["S2853","Carfilzomib (PR-171)","h9","L1300-10","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"209425,209528,211185","Cancer","Apoptosis related,Autophagy,COVID-19,Proteasome","Proteases","Carfilzomib (PR-171) is an irreversible proteasome inhibitor with IC50 of <5 nM in ANBL-6 cells, displayed preferential in vitro inhibitory potency against the ChT-L activity in the β5 subunit, but little or no effect on the PGPH and T-L activities. Carfilzomib activates prosurvival autophagy and induces cell apoptosis.",719.91,"868540-17-4",50,69.45,"<1",0,"http://selleckchem.com/products/carfilzomib-pr-171.html","C40H57N5O7","free base","N/A","CC(C)CC(NC(=O)C(CCC1=CC=CC=C1)NC(=O)CN2CCOCC2)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC(C)C)C(=O)C4(C)CO4",3.799,7,4,20]
["S2868","Alogliptin (SYR-322) benzoate","a10","L1300-10","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"210073,210159,210172,210213,210240","Endocrinology/Metabolic Disease","DPP","Proteases","Alogliptin (SYR-322) benzoate is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.",461.51,"850649-62-6",68,147.34,2,4.33,"http://selleckchem.com/products/alogliptin-syr-322.html","C18H21N5O2.C7H6O2","benzoate","SYR-322","CN1C(=O)C=C(N2CCCC(N)C2)N(CC3=CC=CC=C3C#N)C1=O",1.271,2,1,3]
["S2874","Camostat Mesilate","b10","L1300-10","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Cancer/Infection/Inflammation","COVID-19,Sodium Channel","Transmembrane Transporters","Camostat (FOY-305, FOY-S980) is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.",494.52,"59721-29-8",99,200.19,10,20.22,"http://selleckchem.com/products/camostat-mesilate-foy-305.html","C20H22N4O5.CH4O3S","Mesilate","FOY-305, FOY-S980","CN(C)C(=O)COC(=O)CC1=CC=C(OC(=O)C2=CC=C(NC(N)=N)C=C2)C=C1.C[S](O)(=O)=O",0.969,5,2,10]
["S2875","Prucalopride","c10","L1300-10","in 10mM DMSO","FDA,EMA,HMA,CFDA,NDC",null,"210166","Angiology/Gastroenterology/Respiratory Disease","5-HT Receptor","Neuronal Signaling","Prucalopride (R-93877) is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively, exhibits >290-fold selectivity against other 5-HT receptor subtypes.",367.87,"179474-81-8",60,163.1,"<1",0,"http://selleckchem.com/products/prucalopride.html","C18H26ClN3O3","Free Base","R-93877","COCCCN1CCC(CC1)NC(=O)C2=CC(=C(N)C3=C2OCC3)Cl",1.056,3,2,6]
["S2883","4-Aminohippuric Acid","d10","L1300-10","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,BP2017",null,"Diagnosis","Others","Others","4-Aminohippuric acid is a typical substrate of organic anion transport systems.",194.19,"61-78-9",39,200.83,3,15.45,"http://selleckchem.com/products/4-aminohippuric-acid.html","C9H10N2O3","free base","N/A","NC1=CC=C(C=C1)C(=O)NCC(O)=O",-0.227,2,2,3]
["S2884","Acesulfame Potassium","e10","L1300-10","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017",null,"Others","Others","Others","Acesulfame potassium is a non-nutritive sweetener.",202.25,"55589-62-3",40,197.78,40,197.78,"http://selleckchem.com/products/acesulfame-potassium.html","C4H5NO4S.K","Potassium Salt","N/A","[KH].CC1=CC(=O)N[S](=O)(=O)O1",-0.858,2,1,0]
["S2900","Cobicistat (GS-9350)","f10","L1300-10","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"203094","Infection","P450 (e.g. CYP17)","Metabolism","Cobicistat (GS-9350) is a potent and selective inhibitor of CYP3A with IC50 of 30-285 nM.",776.02,"1004316-88-4",100,128.86,"<1",0,"http://selleckchem.com/products/cobicistat-gs-9350.html","C40H53N7O5S2","free base","N/A","CC(C)C1=NC(=CS1)CN(C)C(=O)NC(CCN2CCOCC2)C(=O)NC(CCC(CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)CC5=CC=CC=C5",4.765,7,3,20]
["S2902","S-Ruxolitinib (INCB018424)","g10","L1300-10","in 10mM DMSO","FDA",null,"202192","Others","JAK","JAK/STAT","S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Phase 3.",306.37,"941685-37-6",61,199.11,5,16.32,"http://selleckchem.com/products/s-ruxolitinib.html","C17H18N6","free base","N/A","N#CCC(C1CCCC1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4",2.88,3,1,4]
["S2903","Lumiracoxib","h10","L1300-10","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Infection","COX","Neuronal Signaling","Lumiracoxib (COX-189) is a novel, selective COX-2 inhibitor with Ki of  0.06 μM. It also inhibits COX1 with Ki of 3 μM.",293.72,"220991-20-8",59,200.87,"<1",0,"http://selleckchem.com/products/lumiracoxib-cox-189.html","C15H13ClFNO2","free base","COX-189","CC1=CC=C(NC2=C(Cl)C=CC=C2F)C(=C1)CC(O)=O",4.4,1,1,4]
["S2907","Pirfenidone (S-7701)","a11","L1300-10","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2016","022535,208780","Respiratory Disease","CCR,TGF-beta/Smad","TGF-beta/Smad","Pirfenidone (S-7701, AMR-69) is an inhibitor for TGF-β production and TGF-β stimulated collagen production, reduces production of TNF-α and IL-1β, and also has anti-fibrotic and anti-inflammatory properties. Pirfenidone attenuates chemokine (CC motif) ligand-2 (CCL2) and CCL12 production with anti-fibrotic activity. Phase 3.",185.22,"53179-13-8",37,199.76,"<1",0,"http://selleckchem.com/products/pirfenidone.html","C12H11NO","free base","AMR-69","CC1=CN(C(=O)C=C1)C2=CC=CC=C2",1.905,1,0,1]
["S2922","Icotinib (BPI-2009H)","b11","L1300-10","in 10mM DMSO","CFDA",null,null,"Cancer/Respiratory Disease","EGFR","Protein Tyrosine Kinase","Icotinib (BPI-2009H) is a potent and specific EGFR inhibitor with IC50 of 5 nM, including the EGFR, EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R).",391.42,"610798-31-7",78,199.27,"<1",0,"http://selleckchem.com/products/icotinib.html","C22H21N3O4","free base","BPI-2009H","C#CC1=CC(=CC=C1)NC2=NC=NC3=C2C=C4OCCOCCOCCOC4=C3",4.128,6,1,2]
["S3000","Carbazochrome sodium sulfonate (AC-17)","c11","L1300-10","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Hematology","Others","Others","Carbazochrome sodium sulfonate (AC-17) is an antihemorrhagic for use in the treatment of hemorrhoids.",322.27,"51460-26-5",64,198.59,3,9.31,"http://selleckchem.com/products/carbazochrome-sodium-sulfonate.html","C10H11N4NaO5S","Sodium","N/A","[Na+].CN1C(CC2=C\\C(=N\\NC(N)=O)C(=O)C=C12)[S]([O-])(=O)=O",-3.186,3,2,2]
["S3001","Clevudine","d11","L1300-10","in 10mM DMSO","marketed in Korea",null,null,"Infection","DNA/RNA Synthesis","DNA Damage/DNA Repair","Clevudine(Levovir,L-FMAU) is an antiviral drug for the treatment of hepatitis B.",260.22,"163252-36-6",52,199.83,52,199.83,"http://selleckchem.com/products/clevudine-levovir.html","C10H13FN2O5","free base","Levovir,L-FMAU","CC1=CN(C2OC(CO)C(O)C2F)C(=O)NC1=O",-1.065,3,3,2]
["S3002","Rivaroxaban (BAY 59-7939)","e11","L1300-10","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","022406,202439","Hematology/Respiratory Disease","Factor Xa","Metabolism","Rivaroxaban (BAY 59-7939) is a direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0.7 nM in cell-free assays, respectively. It is selective for human factor Xa, for which it has >10 000-fold greater selectivity than for other biologically relevant serine proteases (IC50 >20 μM).",435.88,"366789-02-8",87,199.6,"<1",0,"http://selleckchem.com/products/Rivaroxaban.html","C19H18ClN3O5S","free base","BAY 59-7939","ClC1=CC=C(S1)C(=O)NCC2CN(C(=O)O2)C3=CC=C(C=C3)N4CCOCC4=O",1.797,5,1,5]
["S3003","Prostaglandin E2 (PGE2)","f11","L1300-10","in 10mM DMSO","DMF,CFDA",null,null,"Endocrinology","PGES,Prostaglandin Receptor","Endocrinology & Hormones","Prostaglandin E2 (PGE2, Dinoprostone,Prepidil) plays important effects in labour (softens cervix and causes uterine contraction) and also stimulates osteoblasts to release factors that stimulate bone resorption by osteoclasts.",352.47,"363-24-6",70,198.6,40,113.49,"http://selleckchem.com/products/prostaglandin-e2-cervidil.html","C20H32O5","free base","Dinoprostone,Prepidil","CCCCCC(O)/C=C/C1C(O)CC(=O)C1C\\C=C/CCCC(O)=O",3.199,2,2,12]
["S3005","Paroxetine HCl","g11","L1300-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","075356,075566,075716,076618,076968,077082,077395,077584,077873,078026,078194,078406,078902,091427,204134,204744,205528,209293","Psychotic disorders","Serotonin Transporter","Neuronal Signaling","Paroxetine HCl (BRL-29060A, FG-7051) is an antidepressant drug of the SSRI type.",365.83,"78246-49-8",73,199.55,1,2.73,"http://selleckchem.com/products/paroxetine-hcl.html","C19H20FNO3.HCl","Hydrochloride","BRL-29060A, FG-7051","Cl.FC1=CC=C(C=C1)C2CCNCC2COC3=CC4=C(OCO4)C=C3",3.611,3,1,4]
["S3008","Zaltoprofen","h11","L1300-10","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Inflammation","COX","Neuronal Signaling","Zaltoprofen(CN100,Soleton) is an inhibitor of COX-1 and COX-2 for treatment of arthritis.",298.36,"74711-43-6",60,201.1,"<1",0,"http://selleckchem.com/products/zaltoprofen.html","C17H14O3S","free base","CN100,Soleton","CC(C(O)=O)C1=CC2=C(SC3=CC=CC=C3C(=O)C2)C=C1",3.684,2,0,2]
["S3012","Pazopanib","a2","L1300-11","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","022465","Angiology/Cancer","Autophagy,Cathepsin B,c-Kit,CSF-1R,Cysteine Protease,FGFR,PDGFR,VEGFR","Protein Tyrosine Kinase","Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms/CSF1R with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively. Pazopanib induces cathepsin B activation and autophagy.",437.52,"444731-52-6",87,198.85,"<1",0,"http://selleckchem.com/products/pazopanib.html","C21H23N7O2S","Free Base","GW786034","C[N]1N=C2C=C(C=CC2=C1C)N(C)C3=NC(=NC=C3)NC4=CC=C(C)C(=C4)[S](N)(=O)=O",3.741,5,2,5]
["S3015","Amoxicillin","b2","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,EP9.1,JP17,BP2017,Ph.Int_6th,USP36-NF31,IP2010","061926,061931,062058,062059,062067,062090,062528,062853,062854,062881,062884,062927,062946,063001,063030,063031,064013,064031,064076,064131,064139,065016,065021,065056,065059,065060,065113,065119,065228,065255,065256,065271,065291,065319,065322,065324,065325,065334,065344,065378,065387,204030","Infection","Antibiotics,Bacterial","Microbiology","Amoxicillin (Amoxycillin) is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms.",365.4,"26787-78-0",73,199.78,"<1",0,"http://selleckchem.com/products/amoxicillin-amoxycillin.html","C16H19N3O5S","Free Base","Amoxycillin","CC1(C)SC2C(NC(=O)C(N)C3=CC=C(O)C=C3)C(=O)N2C1C(O)=O",-2.539,3,3,4]
["S3017","Aspirin (NSC 27223)","c2","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP39-NF34,BP2015,JP16,IP2010","016030","Inflammation/Neurological Disease","Autophagy,COX,Mitophagy","Metabolism","Aspirin (NSC 27223, Acetylsalicylic acid, ASA) is a salicylate, and irreversible COX1 and COX2 inhibitor, used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. Aspirin induces autophagy and stimulates mitophagy.",180.16,"50-78-2",36,199.82,"<1",0,"http://selleckchem.com/products/aspirin-acetylsalicylic-acid.html","C9H8O4","free base","Acetylsalicylic acid, ASA","CC(=O)OC1=C(C=CC=C1)C(O)=O",1.227,3,0,3]
["S3018","Niflumic acid","d2","L1300-11","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","COX,GABA Receptor","Neuronal Signaling","Niflumic acid(Nifluril) is an inhibitor of cyclooxygenase-2 used for joint and muscular pain.",282.22,"4394-00-7",56,198.43,"<1",0,"http://selleckchem.com/products/niflumic-acid.html","C13H9F3N2O2","free base","Nifluril","OC(=O)C1=CC=CN=C1NC2=CC=CC(=C2)C(F)(F)F",3.34,2,1,4]
["S3019","Ciclopirox ethanolamine","e2","L1300-11","in 10mM DMSO","DMF,CFDA,NDC,HMA",null,null,"Infection","ATPase,Fungal","Transmembrane Transporters","Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296,Ciclopiroxolamine) is a broad-spectrum antifungal agent working as an iron chelator.",268.35,"41621-49-2",6,22.36,"<1",0,"http://selleckchem.com/products/ciclopirox-ethanolamine.html","C12H17NO2.C2H7NO","Ethanolamine","Ciclopirox olamine, HOE 296,Ciclopiroxolamine","CC1=CC(=O)N(O)C(=C1)C2CCCCC2.NCCO",1.302,1,2,2]
["S3021","Rimonabant (SR141716)","f2","L1300-11","in 10mM DMSO","DMF,EMA","Martindale:The Extra Pharmacopoeia",null,"Metabolic Disease","Acyltransferase,Bacterial,Cannabinoid Receptor,MmpL3,Transferase","GPCR & G Protein","Rimonabant (SR141716) is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Rimonabant is also a dual inhibitor of acyl CoA:cholesterol acyltransferases(ACAT) 1 and 2 and inhibits mycobacterial MmpL3.",463.79,"168273-06-1",25,53.9,"<1",0,"http://selleckchem.com/products/rimonabant-sr141716.html","C22H21Cl3N4O","free base","SR141716","CC1=C([N](N=C1C(=O)NN2CCCCC2)C3=CC=C(Cl)C=C3Cl)C4=CC=C(Cl)C=C4",6.613,2,1,4]
["S3022","Cabazitaxel (XRP6258)","g2","L1300-11","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"207381,207619,207693,207735,207736,207949","Cancer","Autophagy,Microtubule Associated","Cytoskeletal Signaling","Cabazitaxel (RPR-116258A, XRP6258, TXD 258, Taxoid XRP6258) is a semi-synthetic derivative of a natural taxoid that kills cancer cells by inhibiting cell division and growth. Cabazitaxel exerts its effects by inhibiting microtubule growth and assembly, processes that are essential for cells to divide. Cabazitaxel induces autophagy via the PI3K/Akt/mTOR pathway.",835.93,"183133-96-2",100,119.63,"<1",0,"http://selleckchem.com/products/cabazitaxel-jevtana.html","C45H57NO14","free base","RPR-116258A, TXD 258, Taxoid XRP6258","COC1CC2OCC2(OC(C)=O)C3C(OC(=O)C4=CC=CC=C4)C5(O)CC(OC(=O)C(O)C(NC(=O)OC(C)(C)C)C6=CC=CC=C6)C(=C(C(OC)C(=O)C13C)C5(C)C)C",3.403,12,2,15]
["S3023","Bufexamac","h2","L1300-11","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017,JP15",null,"Immunology/Inflammation","COX,IFN","Neuronal Signaling","Bufexamac(Bufexamic acid) is a COX inhibitor for IFN-α release with EC50 of 8.9 μM.",223.27,"2438-72-4",45,201.55,"<1",0,"http://selleckchem.com/products/bufexamac.html","C12H17NO3","free base","Bufexamic acid","CCCCOC1=CC=C(CC(=O)NO)C=C1",2.191,2,1,6]
["S3024","Lamotrigine","a3","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017,IP2010","076388,076420,076630,076701,076708,076928,077392,077420,077428,077633,077757,077783,078009,078134,078310,078409,078443,078525,078625,078645,078669,078691,078947,078956,078982,079099,079132,079204,090169,090170,090401,090607,200220,200672,200694,200828,201168,201374,201791,202383,202383,202498,202887,203370,203733,204158,206382,207497","Neurological Disease","5-HT Receptor,Sodium Channel","Transmembrane Transporters","Lamotrigine (BW-430C,LTG) is a novel anticonvulsant drug for inhibition of 5-HT with IC50 of 240 μM and 474 μM in human platelets and rat brain synaptosomes, and also is a sodium channel blocker.",256.09,"84057-84-1",10,39.05,"<1",0,"http://selleckchem.com/products/lamotrigine.html","C9H7Cl2N5","free base","BW-430C,LTG","NC1=NC(=C(N=N1)C2=CC=CC(=C2Cl)Cl)N",2.426,3,2,1]
["S3027","Fenoprofen calcium hydrate","b3","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017","071738,072165,072194,072214,072267,072274,072293,072294,072307,072308,072309,072326,072355,072356,072357,072362,072394,072395,072396,072407,072429,072437,072438,072472,072557,072602,072902,072946,072981,072982","Immunology/Inflammation/Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Fenoprofen calcium hydrate(Fenoprofen calcium salt dihydrate,Feprona dihydrate,Progesic dihydrate) is a non-steroidal anti-inflammatory drug (NSAID).",558.63,"71720-56-4, 53746-45-5",48,85.92,"<1",0,"http://selleckchem.com/products/fenoprofen-calcium-hydrate.html","C30H30CaO8","Calcium dihydrate salt","Fenoprofen calcium salt dihydrate,Feprona dihydrate,Progesic dihydrate","O.O.CC(C(=O)O[Ca]OC(=O)C(C)C1=CC=CC(=C1)OC2=CC=CC=C2)C3=CC=CC(=C3)OC4=CC=CC=C4",6.802,6,0,12]
["S3030","Niclosamide (BAY2353)","c3","L1300-11","in 10mM DMSO","FDA,CFDA,DMF","Martindale the Extra Pharmacopoei,EP9.2,Ph.Int_6th,BP2017,IP2010","018669","Infection/Parasite","Autophagy,STAT","JAK/STAT","Niclosamide (BAY2353, Niclocide, NSC 178296) can inhibit DNA replication and inhibit STAT3 with IC50 of 0.7 μM in a cell-free assay. Niclosamide selectively inhibited the phosphorylation of STAT3 and had no obvious inhibition against the activation of other homologues (e.g., STAT1 and STAT5).",327.12,"50-65-7",8,24.46,"<1",0,"http://www.selleck.cn/products/niclosamide-niclocide.html","C13H8Cl2N2O4","Free Base","Niclocide, NSC 178296","OC1=CC=C(Cl)C=C1C(=O)NC2=C(Cl)C=C(C=C2)[N+]([O-])=O",3.595,1,2,3]
["S3031","Linagliptin (BI-1356)","d3","L1300-11","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"208335,208415,208420,208423,208431,208433,208448,208457,208472","Endocrinology/Metabolic Disease","Autophagy,Ferroptosis","Proteases","Linagliptin (BI-1356,GSK2118436) is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM and exhibits a 10,000-fold higher selectivity for DPP-4 than for other dipeptidyl peptidases such as DPP-2, DPP-8, and DPP-9. Linagliptin activates glomerular autophagy in a model of type 2 diabetes. DPP4 mediates ferroptosis in TP53-deficient CRC cells.",472.54,"668270-12-0",17,35.98,"<1",0,"http://selleckchem.com/products/linagliptin-bi-1356.html","C25H28N8O2","free base","GSK2118436","CC#CC[N]1C(=NC2=C1C(=O)N(CC3=NC4=CC=CC=C4C(=N3)C)C(=O)N2C)N5CCCC(N)C5",2.718,5,1,5]
["S3033","Vildagliptin (LAF-237)","e3","L1300-11","in 10mM DMSO","DMF,EMA,HMA,CFDA,PMDA","Martindale:The Extra Pharmacopoeia",null,"Endocrinology/Metabolic Disease","DPP","Proteases","Vildagliptin (LAF-237,NVP-LAF 237) inhibits DPP−4 with IC50 of 2.3 nM.",303.4,"274901-16-5",60,197.76,60,197.76,"http://selleckchem.com/products/vildagliptin-laf-237.html","C17H25N3O2","free base","NVP-LAF 237","O[C]12CC3[CH2]C(C1)C[C](C3)(C2)NCC(=O)N4CCCC4C#N",0.179,1,1,3]
["S3035","Daunorubicin (RP 13057) HCl","f3","L1300-11","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,IP2010","050731,064212,065000,065034,065035,206195,208759","Cancer","ADC Cytotoxin,Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,COVID-19,DNA/RNA Synthesis,Topoisomerase","DNA Damage/DNA Repair","Daunorubicin HCl (Daunomycin, RP 13057, Rubidomycin) inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM in a cell-free assay. Daunorubicin is a topoisomerase II inhibitor that induces apoptosis.",563.98,"23541-50-6",100,177.31,100,177.31,"http://selleckchem.com/products/daunorubicin-hcl-daunomycin-hcl.html","C27H29NO10.HCl","Hydrochloride","Daunomycin HCl, Rubidomycin HCl","Cl.COC1=C2C(=O)C3=C(C(=C4CC(O)(CC(OC5CC(N)C(O)C(C)O5)C4=C3O)C(C)=O)O)C(=O)C2=CC=C1",1.01,6,4,4]
["S3036","Pravastatin sodium","g3","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,USP39-NF34,EP9.1,JP17,BP2017,IP2010","076056,076341,076397,076445,076714,076939,077013,077491,077730,077751,077793,077904,077917,077987,079187,203367,206061,207068,209869","Cardiovascular Disease/Metabolic Disease","HMG-CoA Reductase","Metabolism","Pravastatin sodium (CS-514) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.",446.51,"81131-70-6",89,199.32,89,199.32,"http://selleckchem.com/products/pravastatin-pravachol.html","C23H35O7.Na","sodium","CS-514 Sodium","[Na+].CCC(C)C(=O)OC1CC(O)C=C2C=CC(C)C(CCC(O)CC(O)CC([O-])=O)C12",0.682,2,3,11]
["S3037","Bepotastine Besilate","h3","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,JP17","206066,206080,206220","Immunology/Inflammation","COVID-19,Histamine Receptor","Neuronal Signaling","Bepotastine Besilate (TAU 284) is a non-sedating, selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7.",547.06,"190786-44-8",109,199.25,"<1",0,"http://selleckchem.com/products/bepotastine-besilate.html","C21H25ClN2O3.C6H6O3S","Besilate salt","TAU 284","OC(=O)CCCN1CCC(CC1)OC(C2=CC=C(Cl)C=C2)C3=NC=CC=C3.O[S](=O)(=O)C4=CC=CC=C4",1.371,3,0,9]
["S3038","Fosaprepitant dimeglumine salt","a4","L1300-11","in 10mM DMSO","FDA,DMF,NDC",null,"203939,204845,206197,209965,210689","Cancer","Neurokinin Receptor","Neuronal Signaling","Fosaprepitant dimeglumine salt (MK-0517) is a water-soluble phosphoryl prodrug for Aprepitant which is a NK1 antagonist.",1004.83,"265121-04-8",201,200.03,135,134.35,"http://selleckchem.com/products/fosaprepitant.html","C23H22F7N4O6P.2C7H17NO5","dimeglumine salt","MK-0517","CNCC(O)C(O)C(O)C(O)CO.CNCC(O)C(O)C(O)C(O)CO.CC(OC1OCCN(CC2=NN(C(=O)N2)[P](O)(O)=O)C1C3=CC=C(F)C=C3)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F",-1.235,4,13,21]
["S3043","Rofecoxib","b4","L1300-11","in 10mM DMSO","FDA,DMF,HMA","Martindale:The Extra Pharmacopoeia","021042,021052,021647","Inflammation/Neurological Disease","COX","Neuronal Signaling","Rofecoxib (MK-0966) is a COX-2 inhibitor with IC50 of 18 nM.",314.36,"162011-90-7",63,200.41,"<1",0,"http://selleckchem.com/products/rofecoxib-vioxx.html","C17H14O4S","free base","MK-0966","C[S](=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3",2.871,4,0,3]
["S3045","Cinepazide maleate","c4","L1300-11","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Angiology/Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Cinepazide maleate is a maleate salt form of cinepazide which is a vasodilator.",533.57,"26328-04-1",107,200.54,107,200.54,"http://selleckchem.com/products/cinepazide-maleate.html","C22H31N3O5.C4H4O4","Maleate","N/A","COC1=C(OC)C(=CC(=C1)/C=C/C(=O)N2CCN(CC2)CC(=O)N3CCCC3)OC.OC(=O)\\C=C/C(O)=O",-1.65,7,0,9]
["S3046","Azilsartan","d4","L1300-11","in 10mM DMSO","PMDA",null,null,"Cardiovascular Disease","Angiotensin Receptor","GPCR & G Protein","Azilsartan (TAK-536) is an angiotensin II type 1 (AT1) receptor antagonist with IC50 of 2.6 nM.",456.45,"147403-03-0",91,199.36,"<1",0,"http://selleckchem.com/products/azilsartan-tak-536.html","C25H20N4O5","free base","TAK-536","CCOC1=NC2=CC=CC(=C2[N]1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)ON5)C(O)=O",4.662,6,1,7]
["S3047","Otilonium Bromide","e4","L1300-11","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","AChR","Neuronal Signaling","Otilonium bromide is an antimuscarinic.",563.57,"26095-59-0",113,200.51,113,200.51,"http://selleckchem.com/products/otilonium-bromide.html","C29H43BrN2O4","quaternary-N bromide salt","N/A","[Br-].CCCCCCCCOC1=CC=CC=C1C(=O)NC2=CC=C(C=C2)C(=O)OCC[N+](C)(CC)CC",2.67,4,1,17]
["S3051","Bosentan Hydrate","f4","L1300-11","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Endothelin Receptor","GPCR & G Protein","Bosentan (Ro 47-0203) is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.",569.63,"157212-55-0",100,175.55,0,0,"http://selleckchem.com/products/bosentan-hydrate.html","C27H29N5O6S.H2O","Hydrate","Ro 47-0203","O.COC1=CC=CC=C1OC2=C(OCCO)N=C(N=C2N[S](=O)(=O)C3=CC=C(C=C3)C(C)(C)C)C4=NC=CC=N4",3.741,9,2,11]
["S3052","Rupatadine Fumarate","g4","L1300-11","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.3",null,"Immunology","Histamine Receptor","Neuronal Signaling","Rupatadine is an inhibitor of PAFR and histamine (H1) receptor with Ki of 550 nM and 102 nM, respectively.",532.03,"182349-12-8",9,16.92,"<1",0,"http://selleckchem.com/products/rupatadine-fumarate.html","C26H26ClN3.C4H4O4","Fumarate","N/A","CC1=CN=CC(=C1)CN2CCC(CC2)=C3C4=CC=C(Cl)C=C4CCC5=CC=CN=C35.OC(=O)\\C=C\\C(O)=O",2.672,4,0,4]
["S3053","Azelnidipine","h4","L1300-11","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Azelnidipine (UR-12592) is a dihydropyridine calcium channel blocker.",582.65,"123524-52-7",117,200.81,"<1",0,"http://selleckchem.com/products/azelnidipine.html","C33H34N4O6","free base","UR-12592","CC(C)OC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OC3CN(C3)C(C4=CC=CC=C4)C5=CC=CC=C5)N",4.941,4,2,11]
["S3054","Alverine Citrate","a5","L1300-11","in 10mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia,EP9.3,BP2017",null,"Gastroenterology","5-HT Receptor","Neuronal Signaling","Alverine citrate (NSC 35459) is a drug used for functional gastrointestinal disorders. Alverine citrate is a 5-HT1A receptor antagonist, with an IC50 of 101 nM.",473.56,"5560-59-8",95,200.61,"<1",0,"http://selleckchem.com/products/alverine-citrate.html","C20H27N.C6H8O7","Citrate","NSC 35459","CCN(CCCC1=CC=CC=C1)CCCC2=CC=CC=C2.OC(=O)CC(O)(CC(O)=O)C(O)=O",1.037,3,0,14]
["S3057","Azilsartan Medoxomil","b5","L1300-11","in 10mM DMSO","DMF,EMA,HMA",null,null,"Cardiovascular Disease","Angiotensin Receptor","GPCR & G Protein","Azilsartan Medoxomil (TAK-491) is a potent angiotensin II type 1 (AT1) receptor antagonist, inhibits the RAAS, with an IC50 of 2.6 nM, exhibits >10,000-fold selectivity over AT2.",568.53,"863031-21-4",114,200.52,"<1",0,"http://selleckchem.com/products/azilsartan-medoxomil-tak-491.html","C30H24N4O8","free base","TAK-491","CCOC1=NC2=CC=CC(=C2[N]1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)ON5)C(=O)OCC6=C(C)OC(=O)O6",5.27,10,1,10]
["S3060","Medetomidine HCl","c5","L1300-11","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Adrenergic Receptor","Neuronal Signaling","Medetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.",236.74,"86347-15-1",12,50.69,47,198.53,"http://selleckchem.com/products/medetomidine-hcl.html","C13H16N2.HCl","HCl","N/A","Cl.CC(C1=C[NH]C=N1)C2=C(C)C(=CC=C2)C",3.515,1,1,2]
["S3061","Epinephrine HCl","d5","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,BP2015,USP38-NF33,IP2010","087907,205029,207568,209359","Immunology/Inflammation/Neurological Disease","Adrenergic Receptor","Neuronal Signaling","Epinephrine HCl (Adrenaline) is a hormone and a neurotransmitter.",219.67,"55-31-2",44,200.3,44,200.3,"http://selleckchem.com/products/epinephrine-hcl-adrenaline.html","C9H13NO3.HCl","HCl","Adrenaline","Cl.CNCC(O)C1=CC=C(O)C(=C1)O",0.754,0,4,3]
["S3062","Diclofenac Potassium","e5","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","075152,075219,075229,075463,075470,075582,076561,202964,204648","Immunology/Inflammation/Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Diclofenac potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.",334.24,"15307-81-0",69,206.44,10,29.92,"http://selleckchem.com/products/diclofenac-potassium.html","C14H10Cl2KNO2","Potassium","CGP-45840B","[K+].[O-]C(=O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl",2.899,0,1,4]
["S3063","Diclofenac Diethylamine","f5","L1300-11","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,BP2017",null,"Immunology/Inflammation/Neurological Disease","COX","Neuronal Signaling","Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions. Diclofenac exerts its action via inhibition of prostaglandin synthesis by inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) with relative equipotency.",369.29,"78213-16-8",74,200.38,"<1",0,"http://selleckchem.com/products/diclofenac-diethylamine.html","C14H11Cl2NO2.C4H11N","Diethylamine","N/A","CCNCC.OC(=O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl",2.15,1,2,6]
["S3066","Naloxone HCl","g5","L1300-11","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,P2010","070678,070679,070680","Neurological Disease","Opioid Receptor","Neuronal Signaling","Naloxone HCl is an opioid inverse agonist drug used to counter the effects of opiate overdose.",363.84,"357-08-4",72,197.89,72,197.89,"http://selleckchem.com/products/naloxone-hcl.html","C19H21NO4.HCl","HCl","N/A","Cl.OC1=C2OC3C(=O)CCC4(O)C5CC(=C2C34CCN5CC=C)C=C1",1.835,2,1,2]
["S3067","Chlorhexidine 2HCl","h5","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","019490,020111,021669,072525,074291,074356,074522,075006,075561,077789","Infection","Anti-infection","Microbiology","Chlorhexidine hydrochloride (NSC-185) is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.",578.37,"3697-42-5",100,172.9,"<1",0,"http://selleckchem.com/products/chlorhexidine-hcl.html","C22H30Cl2N10.2HCl","HCl","NSC-185","Cl.Cl.ClC1=CC=C(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC2=CC=C(Cl)C=C2)C=C1",5.137,0,6,17]
["S3070","Piracetam","a6","L1300-11","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,KP Ⅹ,EP9.2,BP2017",null,"Neurological Disease","GluR","Neuronal Signaling","Piracetam (UCB 6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders.",142.16,"7491-74-9",72,506.47,72,506.47,"http://selleckchem.com/products/piracetam.html","C6H10N2O2","free base","UCB 6215","NC(=O)CN1CCCC1=O",-1.312,2,1,2]
["S3071","Vanillin","b6","L1300-11","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010",null,"Infection","Others","Others","Vanillin (FEMA 3107), 4-hydroxy-3-methoxybenzaldehyde is a food additive.",152.15,"121-33-5",30,197.17,"<1",0,"http://selleckchem.com/products/vanillin.html","C8H8O3","free base","FEMA 3107","COC1=CC(=CC=C1O)C=O",1.33,2,1,2]
["S3074","Chlorthalidone","c6","L1300-11","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37,IP2010","086831,087029,087050,087082,087100,087118,087176,087247,087292,087293,087296,087311,087312,087364,087380,087381,087384,087450,087451,087473,087515,087516,087521,087555,087689,087698,087699,087706,087947,088012,088073,088139,088140,088164,088651,088902,088903,089051,089052,089285,089286,089591,089738,089739,206904,207222,207813,210742,211063","Cardiovascular Disease/Metabolic Disease","Sodium Channel","Transmembrane Transporters","Chlortalidone (Chlortalidone) is a diuretic drug widely used in antihypertensive therapy.",338.77,"77-36-1",67,197.77,"<1",0,"http://selleckchem.com/products/chlorthalidone-chlortalidone.html","C14H11ClN2O4S","free base","Chlortalidone","N[S](=O)(=O)C1=CC(=CC=C1Cl)C2(O)NC(=O)C3=C2C=CC=C3",1.383,3,2,2]
["S3077","Tazobactam","d6","L1300-11","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,JP17","065362,065363,065386,065446,065458,065498,065523,090498,203557,203719,203720,204959,206204,206996,207146,207847,207848","Infection","Selection Antibiotics for Transfected Cell,β-lactamase","Microbiology","Tazobactam (Tazobactam acid, Tazobactamum) is a β-lactamases Inhibitor with antibacterial activity. It also inhibits the class D oxacillinase OXA-2. It is used in combination with piperacillin and other β-lactam antibiotics to broaden their spectrum and enhance their effect.",300.29,"89786-04-9",60,199.81,"<1",0,"http://selleckchem.com/products/tazobactam.html","C10H12N4O5S","free base","Tazobactam acid, Tazobactamum","CC1(C[N]2C=CN=N2)C(N3C(CC3=O)[S]1(=O)=O)C(O)=O",-1.189,6,0,3]
["S3078","Beclomethasone dipropionate","e6","L1300-11","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37,KP Ⅹ,IP2010","018153,018584,202813,020911,020911,018521,017573,020486","Immunology/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Beclomethasone dipropionate(Beclovent,Beconase,Vancenase)  is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.",521.04,"5534-09-8",104,199.6,"<1",0,"http://selleckchem.com/products/beclomethasone-dipropionate.html","C28H37ClO7","free base","Beclometasone dipropionate,Beclovent,Beconase,Vancenase","CCC(=O)OCC(=O)C1(OC(=O)CC)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(Cl)C(O)CC12C",4.064,6,1,8]
["S3079","Atovaquone","f6","L1300-11","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","202960,207833,209105,209685,209750,210510,210692","Infection/Parasitology/Respiratory Disease","COVID-19,Fungal,Parasite","Microbiology","Atovaquone (Atavaquone) is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.",366.84,"95233-18-4",5,13.63,"<1",0,"http://selleckchem.com/products/atovaquone-atavaquone.html","C22H19ClO3","free base","Atavaquone","OC1=C(C2CCC(CC2)C3=CC=C(Cl)C=C3)C(=O)C4=C(C=CC=C4)C1=O",5.319,2,1,2]
["S3080","Etravirine (TMC125)","g6","L1300-11","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","022187","Infection","Reverse Transcriptase","Microbiology","Etravirine (TMC125, R-165335) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.",435.28,"269055-15-4",42,96.49,"<1",0,"http://selleckchem.com/products/etravirine-tmc125.html","C20H15BrN6O","free base","R-165335","CC1=CC(=CC(=C1OC2=C(Br)C(=NC(=N2)NC3=CC=C(C=C3)C#N)N)C)C#N",5.492,3,2,4]
["S3081","Ulipristal Acetate (CDB 2914)","h6","L1300-11","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC",null,"022474","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Ulipristal acetate (CDB-2914, HRP 2000, RU 44675) is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.",475.62,"126784-99-4",83,191.43,"<1",0,"http://selleckchem.com/products/ulipristal.html","C30H37NO4","free base","HRP 2000, RU 44675","CN(C)C1=CC=C(C=C1)C2CC3(C)C(CCC3(OC(C)=O)C(C)=O)C4CCC5=CC(=O)CCC5=C24",4.309,2,0,3]
["S3083","Indacaterol Maleate","a7","L1300-11","in 10mM DMSO","FDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","022383","Inflammation/Respiratory Disease","Adrenergic Receptor","Neuronal Signaling","Indacaterol (QAB149) is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor.",508.56,"753498-25-8",102,200.57,"<1",0,"http://selleckchem.com/products/indacaterol-maleate.html","C24H28N2O3.C4H4O4","Maleate","QAB149","CCC1=CC2=C(CC(C2)NCC(O)C3=CC=C(O)C4=C3C=CC(=O)N4)C=C1CC.OC(=O)\\C=C/C(O)=O",1.264,3,4,8]
["S3100","2-Thiouracil","b7","L1300-11","in 10mM DMSO","DMF",null,null,"Others","Hydroxylase","Neuronal Signaling","2-Thiouracil(Deracil,Thiouracil) is a thiolated uracil derivative that is a known antihyperthyroid agent.",128.15,"141-90-2",26,202.89,"<1",0,"http://selleckchem.com/products/2-thiouracil.html","C4H4N2OS","free base","Deracil,Thiouracil","O=C1NC(=S)NC=C1",0.081,1,2,0]
["S3104","Moguisteine","c7","L1300-11","in 10mM DMSO","marketed in Italy",null,null,"Respiratory Disease","Others","Others","Moguisteine(BBR-2173) is a novel peripheral non-narcotic antitussive drug.",339.41,"119637-67-1",68,200.35,"<1",0,"http://selleckchem.com/products/moguisteine.html","C16H21NO5S","free base","BBR-2173","CCOC(=O)CC(=O)N1CCSC1COC2=CC=CC=C2OC",2.212,5,0,8]
["S3105","Nadifloxacin","d7","L1300-11","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Infection","Antibiotics","Microbiology","Nadifloxacin (OPC-7251) is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris.",360.38,"124858-35-1",20,55.5,"<1",0,"http://selleckchem.com/products/nadifloxacin.html","C19H21FN2O4","free base","OPC-7251","CC1CCC2=C3N1C=C(C(O)=O)C(=O)C3=CC(=C2N4CCC(O)CC4)F",1.865,2,1,2]
["S3106","Pidotimod","e7","L1300-11","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Immunology/Infection","Immunology & Inflammation related","Immunology & Inflammation","Pidotimod(Pidotomod) is an immunostimulant.",244.27,"121808-62-6",49,200.6,10,40.94,"http://selleckchem.com/products/pidotimod.html","C9H12N2O4S","free base","Pidotomod","OC(=O)C1CSCN1C(=O)C2CCC(=O)N2",-0.939,3,1,2]
["S3113","Pyridoxine HCl","f7","L1300-11","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","080572,080581,080618,080669,080761,083760,083771,083772,087967,204879","Neurological Disease","Vitamin","Metabolism","Pyridoxine HCl (Vitamin B6,Pyridoxol hydrochloride) is a form of vitamin B6.",205.64,"58-56-0",41,199.38,41,199.38,"http://selleckchem.com/products/pyridoxine-hydrochloride.html","C8H11NO3.HCl","Hydrochloride","Vitamin B6,Pyridoxol hydrochloride","Cl.CC1=C(O)C(=C(CO)C=N1)CO",-0.108,1,3,2]
["S3114","Vitamin C","g7","L1300-11","in 10mM DMSO","DMF,CFDA,NDC,HMA","USP32-NF27",null,"Nutritional support","Vitamin","Metabolism","Vitamin C (L-Ascorbic acid) is a water-soluble vitamin indicated for the prevention and treatment of scurvy.",176.12,"50-81-7",35,198.73,35,198.73,"http://selleckchem.com/products/vitamin-c-ascorbic-acid.html","C6H8O6","free base","L-Ascorbic acid","OCC(O)C1OC(=O)C(=C1O)O",-1.709,2,4,2]
["S3116","Sulfathiazole","h7","L1300-11","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","080086,080280,086424,087285,087864,088462,088463","Infection","Anti-infection","Microbiology","Sulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug.",255.32,"72-14-0",51,199.75,"<1",0,"http://selleckchem.com/products/sulfathiazole.html","C9H9N3O2S2","free base","N/A","NC1=CC=C(C=C1)[S](=O)(=O)NC2=NC=CS2",0.568,3,2,3]
["S3117","Oxybutynin hydrochloride","a8","L1300-11","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37,EP9.1,BP2017","070746,071655,072296,072485,074520,074625,074868,074997,075039,075079,075137,076644,076682,076702,076745,078293,078503,202332,204010,206121,207138,207329,209025,209335,209823,210125,211062,211655,211682","Others","AChR","Neuronal Signaling","Oxybutynin(MJ4309-1) is an anticholinergic medication used to relieve urinary and bladder difficulties.",393.95,"1508-65-2",79,200.53,4,10.15,"https://www.selleckchem.com/products/oxybutynin-hydrochloride.html","C22H31NO3.HCl","hydrochloride","MJ4309-1","Cl.CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)C2=CC=CC=C2",5.028,2,0,10]
["S3120","Doxepin HCl","b8","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","016987,070790,070791,070792,070793,070825,070827,070828,070931,070932,070952,070953,070954,070955,070972,070973,071238,071239,071326,071422,071437,071485,071486,071487,071502,071521,071562,071595,071608,071609,071653,071654,071669,071673,071674,071675,071676,071685,071686,071697,071763,071764,071918,072109,072110,072375,072376,072386,072387,072985,072986,072987,073054,073055,074721,075924,201951,202337,202510,202761,207482,211603","Inflammation/Psychotic disorders","Histamine Receptor","Neuronal Signaling","Doxepin is a tricyclic antidepressant formulated as a mixture of E-(trans) and Z-(cis) stereoisomers. It inhibits CYP2D6 activity in vivo.",315.84,"1229-29-4",63,199.47,63,199.47,"http://selleckchem.com/products/doxepin-hydrochloride-sinequan.html","C19H21NO.HCl","hydrochloride","N/A","Cl.CN(C)CC\\C=C1/C2=CC=CC=C2COC3=C1C=CC=C3",4.29,1,0,3]
["S3121","Ornidazole","c8","L1300-11","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,IP2010",null,"Infection/Parasitology","Bacterial","Microbiology","Ornidazole (Ro7-0207, NSC 95075) is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria.",219.63,"16773-42-5",44,200.34,2,9.11,"http://selleckchem.com/products/ornidazole.html","C7H10ClN3O3","free base","Ro7-0207, NSC 95075","CC1=NC=C([N]1CC(O)CCl)[N+]([O-])=O",0.357,1,1,4]
["S3124","Dexamethasone Acetate","d8","L1300-11","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,EP9.1,EP9.1","084315,087711","Infection","Complement System,COVID-19,IL Receptor","Immunology & Inflammation","Dexamethasone (NSC 39471,Dexamethasone 21-acetate) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator  that has anti-inflammatory and immunosuppressant effects.",434.5,"1177-87-3",87,200.23,"<1",0,"http://selleckchem.com/products/dexamethasone-acetate.html","C24H31FO6","free base","NSC 39471,Dexamethasone 21-acetate","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)COC(C)=O",2.087,4,1,4]
["S3129","Trimethoprim","e8","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,EP9.1,Ph.Int_6th,BP2017,IP2010","018679,070049,070494,070495,071259,091437","Infection","Antibiotics,Bacterial,DHFR","Microbiology","Trimethoprim (BW 56-72, NIH 204, NSC-106568) is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.",290.32,"738-70-5",58,199.78,"<1",0,"http://selleckchem.com/products/trimethoprim.html","C14H18N4O3","free base","BW 56-72, NIH 204, NSC-106568","COC1=C(OC)C(=CC(=C1)CC2=CN=C(N)N=C2N)OC",1.543,5,2,5]
["S3130","Biotin (Vitamin B7)","f8","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.5,JP17,BP2017","006071","Nutritional support","Dyes,Vitamin","Metabolism","Biotin(Vitamin B7) is a water-soluble B-vitamin and is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.",244.31,"58-85-5",49,200.56,"<1",0,"http://selleckchem.com/products/biotin-vitamin-b7.html","C10H16N2O3S","free base","N/A","OC(=O)CCCCC1SCC2NC(=O)NC12",0.67,2,2,5]
["S3132","Sulfamerazine","g8","L1300-11","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017","080123,006317,080079,080099,080100,080013,006904,080086,080280,006920,080094","Infection","Bacterial","Microbiology","Sulfamerazine (RP 2632,sulphamerazine) is a sulfonamide antibacterial.",264.3,"127-79-7",53,200.53,"<1",0,"http://selleckchem.com/products/sulfamerazine.html","C11H12N4O2S","free base","RP 2632,sulphamerazine","CC1=NC(=NC=C1)N[S](=O)(=O)C2=CC=C(N)C=C2",0.595,4,2,3]
["S3133","Sulfamethazine","h8","L1300-11","in 10mM DMSO","FDA,DMF,CFDA","USP42-NF37","080123,006317,080079,080099,080100,080013,006904,080086,080280,006920,080094","Infection/Inflammation","Bacterial","Microbiology","Sulfamethazine(Sulfadimidine,Sulfadimerazine) is a sulfonamide antibacterial.",278.33,"57-68-1",56,201.2,"<1",0,"http://selleckchem.com/products/sulfamethazine.html","C12H14N4O2S","free base","Sulfadimidine,Sulfadimerazine","CC1=NC(=NC(=C1)C)N[S](=O)(=O)C2=CC=C(N)C=C2",0.878,4,2,3]
["S3137","Sodium salicylate","a9","L1300-11","in 10mM DMSO","DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010",null,"Inflammation","NF-κB","NF-κB","Sodium salicylate(2-Hydroxybenzoic acid Sodium salt,Salicylic acid Sodium salt) is used in medicine as an analgesic and antipyretic.",161.11,"54-21-7",32,198.62,32,198.62,"http://selleckchem.com/products/sodium-salicylate.html","C7H6O3.Na","sodium salt","2-Hydroxybenzoic acid Sodium salt,Salicylic acid Sodium salt","[NaH].OC(=O)C1=CC=CC=C1O",1.217,1,1,1]
["S3138","Methylthiouracil","b9","L1300-11","in 10mM DMSO","CFDA",null,null,"Endocrinology/Metabolic Disease","ERK,Interleukins,NF-κB,TNF-alpha","NF-κB","Methylthiouracil (NSC-193526, NSC-9378,MTU) is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.",142.18,"56-04-2",28,196.93,"<1",0,"http://selleckchem.com/products/methylthiouracil.html","C5H6N2OS","free base","NSC-193526, NSC-9378,MTU","CC1=CC(=O)NC(=S)N1",0.595,1,2,0]
["S3140","Milnacipran HCl","c9","L1300-11","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","205062,205071,205081,205267,205286,205367,210944","Neurological Disease/Psychotic disorders","Serotonin Transporter","Neuronal Signaling","Milnacipran inhibits both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively.",282.81,"101152-94-7",57,201.55,57,201.55,"http://selleckchem.com/products/milnacipran-hydrochloride.html","C15H22N2O.HCl","HCl","N/A","Cl.CCN(CC)C(=O)C1(CC1CN)C2=CC=CC=C2",1.67,1,1,5]
["S3144","Darifenacin HBr","d9","L1300-11","in 10mM DMSO","FDA,DMF,EMA,NDC","Martindale:The Extra Pharmacopoeia","091190,205209,205550,206743,207664,207681","Neurological Disease","AChR","Neuronal Signaling","Darifenacin HBr (UK-88525) is a selective M3 muscarinic receptor antagonist with pKi of 8.9.",507.46,"133099-07-7",100,197.06,"<1",0,"http://selleckchem.com/products/darifenacin-hydrobromide.html","C28H30N2O2.HBr","HBr","UK-88525","Br.NC(=O)C(C1CCN(CCC2=CC=C3OCCC3=C2)C1)(C4=CC=CC=C4)C5=CC=CC=C5",5.048,2,1,7]
["S3147","Entacapone","e9","L1300-11","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","078941,090690,202394,203437,205792,206669,207210","Neurological Disease","COMT,Histone Methyltransferase","Epigenetics","Entacapone (OR-611) inhibits catechol-O-methyltransferase(COMT) with IC50 of 151 nM. Entacapone can be used for the research of Parkinson's disease. Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders.",305.29,"130929-57-6",61,199.81,"<1",0,"http://selleckchem.com/products/entacapone.html","C14H15N3O5","free base","OR-611","CCN(CC)C(=O)\\C(=C\\C1=CC(=C(O)C(=C1)O)[N+]([O-])=O)C#N",1.658,1,2,5]
["S3149","Estradiol valerate","f9","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,BP2017","040628,083546,083547,083714,090920","Cancer/Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estradiol(E2V) is a synthetic ester used to treat menopausal symptoms and hormone deficiencies.",356.5,"979-32-8",71,199.16,"<1",0,"http://selleckchem.com/products/estradiol-valerate.html","C23H32O3","free base","E2V","CCCCC(=O)OC1CCC2C3CCC4=CC(=CC=C4C3CCC12C)O",5.796,2,1,5]
["S3150","Articaine HCl","g9","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","079138","Neurological Disease","NF-κB","Immunology & Inflammation","Articaine (Ultracaine) is a dental local anesthetic which contains an additional ester group that is metabolized by estearases in blood and tissue.",320.84,"23964-57-0",64,199.48,64,199.48,"http://selleckchem.com/products/articaine-hydrochloride.html","C13H20N2O3S.HCl","Hydrochloride","Ultracaine","Cl.CCCNC(C)C(=O)NC1=C(SC=C1C)C(=O)OC",2.454,3,2,7]
["S3151","Gliquidone","h9","L1300-11","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,BP2017",null,"Endocrinology/Metabolic Disease","Potassium Channel","Transmembrane Transporters","Gliquidone (Glurenorm,AR-DF 26) is an ATP-sensitive K+ channel antagonist with IC50 of 27.2 nM.",527.63,"33342-05-1",105,199,"<1",0,"http://selleckchem.com/products/gliquidone.html","C27H33N3O6S","free base","Glurenorm,AR-DF 26","COC1=CC2=C(C=C1)C(C)(C)C(=O)N(CCC3=CC=C(C=C3)[S](=O)(=O)NC(=O)NC4CCCCC4)C2=O",4.214,6,2,7]
["S3153","Levalbuterol tartrate","a10","L1300-11","in 10mM DMSO","FDA,NDC",null,"021730","Immunology/Inflammation","Adrenergic Receptor","Neuronal Signaling","Levalbuterol HCl(Levosalbutamol tartrate) is a relatively selective beta2-adrenergic receptor agonist used for the treatment of asthma.",628.71,"661464-94-4",100,159.06,100,159.06,"http://www.selleck.cn/products/levalbuterol-hydrochloride.html","C30H48N2O12","tartrate","Levosalbutamol tartrate","CC(C)(C)NCC(O)C1=CC=C(O)C(=C1)CO.CC(C)(C)NCC(O)C2=CC=C(O)C(=C2)CO.OC(C(O)C(O)=O)C(O)=O",-5.19,2,10,13]
["S3154","Butenafine HCl","b10","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,JP17","205181","Infection","Fungal","Microbiology","Butenafine HCl (KP-363) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.",353.93,"101827-46-7",70,197.78,"<1",0,"http://selleckchem.com/products/butenafine-hydrochloride.html","C23H27N.HCl","HCl","KP-363","Cl.CN(CC1=CC=C(C=C1)C(C)(C)C)CC2=C3C=CC=CC3=CC=C2",6.177,0,0,5]
["S3155","Mepivacaine HCl","c10","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,KP Ⅹ,JP17,BP2017","040806,083559,087509,088769,088770","Neurological Disease","Sodium Channel","Transmembrane Transporters","Mepivacaine is a tertiary amine used as a local anesthetic.",282.81,"1722-62-9",3,10.61,57,201.55,"http://selleckchem.com/products/mepivacaine-hydrochloride.html","C15H22N2O.HCl","HCl","N/A","Cl.CN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",3.363,1,1,2]
["S3160","Ethynodiol diacetate","d10","L1300-11","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","204703,204704","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Ethynodiol diacetate (8080 CB,Ethynodiol acetate) is one of the first synthetic progestogens used in contraceptive pills.",384.51,"297-76-7",77,200.25,77,200.25,"http://selleckchem.com/products/ethynodiol-diacetate.html","C24H32O4","free base","8080 CB,Ethynodiol acetate","CC(=O)OC1CCC2C3CCC4(C)C(CCC4(OC(C)=O)C#C)C3CCC2=C1",4.973,4,0,4]
["S3161","Sertaconazole nitrate","e10","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017","021385","Infection","Fungal","Microbiology","Sertaconazole nitrate (FI-7045,FI7056) is a topical broad-spectrum antifungal that is developed to provide an additional agent for the treatment of superficial cutaneous and mucosal infections.",500.78,"99592-39-9",100,199.69,"<1",0,"http://selleckchem.com/products/sertaconazole-nitrate.html","C20H15Cl3N2OS.HNO3","Nitrate","FI-7045,FI7056","O[N+]([O-])=O.ClC1=CC=C(C(C[N]2C=CN=C2)OCC3=CSC4=C(Cl)C=CC=C34)C(=C1)Cl",4.584,2,0,6]
["S3162","Tylosin tartrate","f10","L1300-11","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017,IP2010",null,"Infection","Antibiotics,Antibiotics for Mammalian Cell Culture","Microbiology","Tylosin tartrate is a macrolide antibiotic approved for the control of mycoplasmosis in poultry.",1066.19,"74610-55-2",300,281.38,200,187.58,"http://selleckchem.com/products/tylosin-tartrate.html","C46H77NO17.C4H6O6","Tartrate","N/A","CCC1OC(=O)CC(O)C(C)C(OC2OC(C)C(OC3CC(C)(O)C(O)C(C)O3)C(C2O)N(C)C)C(CC=O)CC(C)C(=O)\\C=C\\C(=C\\C1COC4OC(C)C(O)C(OC)C4OC)C.OC(C(O)C(O)=O)C(O)=O",-2.989,14,6,16]
["S3163","Benztropine mesylate","g10","L1300-11","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","040103,040706,040715,072264,072265,072266,081265,088510,088511,088514,088877,088894,088895,089058,089059,089060,089211,089212,089213,090168,090233,090287,090294,091152,091525,204713","Neurological Disease","Dopamine Receptor","Neuronal Signaling","Benztropine(Cogentin mesylate, Benztropine methanesulfonate) is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM.",403.53,"132-17-2",50,123.91,81,200.73,"http://selleckchem.com/products/benztropine-mesylate.html","C21H25NO.CH4SO3","Mesylate","Cogentin mesylate, Benztropine methanesulfonate","CN1C2CCC1CC(C2)OC(C3=CC=CC=C3)C4=CC=CC=C4.C[S](O)(=O)=O",3.461,1,0,4]
["S3167","Altrenogest","h10","L1300-11","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Altrenogest (A35957, RU2267,R2267) is a progestogen structurally related to veterinary steroid trenbolone.",310.43,"850-52-2",62,199.72,"<1",0,"http://selleckchem.com/products/altrenogest.html","C21H26O2","free base","A35957, RU2267,R2267","CC12C=CC3=C4CCC(=O)C=C4CCC3C1CCC2(O)CC=C",3.561,1,0,2]
["S3170","Ampicillin sodium","a11","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,KP Ⅹ,EP9.1,JP17,BP2017,Ph.Int_5th,USP39-NF34,IP2010","061395,061936,062565,062634,062692,062719,062738,062772,062797,062816,062860,062994,063142,063147,065493,065499,090354,090581,090583,090884,090889,201025,201404,202198,202864,202865","Infection/Inflammation","Antibiotics,Antibiotics for Mammalian Cell Culture,Selection Antibiotics for Transfected Cell","Microbiology","Ampicillin(D-(-)-α-Aminobenzylpenicillin sodium salt) is a beta-lactam antibiotic that is part of the aminopenicillin family.",371.39,"69-52-3",37,99.63,74,199.25,"http://selleckchem.com/products/ampicillin-sodium.html","C16H18N3NaO4S","Sodium","D-(-)-α-Aminobenzylpenicillin sodium salt","[Na+].CC1(C)SC2C(NC(=O)C(N)C3=CC=CC=C3)C(=O)N2C1C([O-])=O",-1.292,2,2,4]
["S3172","Anagrelide HCl","b11","L1300-11","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","076417,076468,076489,076530,076683,076811,076910,077613,209151","Cancer/Hematology","PDE","Metabolism","Anagrelide (BL-4162A,BMY 26538-01) is a drug used for the treatment of essential thrombocytosis.",292.55,"58579-51-4",14,47.86,"<1",0,"http://selleckchem.com/products/anagrelide-hydrochloride.html","C10H7Cl2N3O.HCl","Hydrochloride","BL-4162A,BMY 26538-01","Cl.ClC1=CC=C2NC3=NC(=O)CN3CC2=C1Cl",2.347,2,1,0]
["S3173","Antipyrine","c11","L1300-11","in 10mM DMSO","DMF,CFDA","USP42-NF37,JP17",null,"Inflammation/Neurological Disease","COX","Neuronal Signaling","Antipyrine (Phenazone,Phenazon) is an analgesic and antipyretic agent; selective COX-3 inhibitor.",188.23,"60-80-0",38,201.88,38,201.88,"http://selleckchem.com/products/antipyrine.html","C11H12N2O","free base","Phenazone,Phenazon","CN1N(C(=O)C=C1C)C2=CC=CC=C2",1.218,1,0,1]
["S3175","Atomoxetine HCl","d11","L1300-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","078940,078983,079016,079017,079019,079020,079021,079022,090609,202682","Neurological Disease","5-HT Receptor","Neuronal Signaling","Atomoxetine (LY 139603) is a selective norepinephrine (NE) transporter inhibitor with Ki of 5 nM, with 15- and 290-fold lower affinity for human 5-HT and DA transporters.",291.82,"82248-59-7",58,198.75,2,6.85,"http://selleckchem.com/products/atomoxetine-hydrochloride.html","C17H21NO.HCl","HCl","LY 139603 HCl","Cl.CNCCC(OC1=CC=CC=C1C)C2=CC=CC=C2",3.959,1,1,6]
["S3176","Betahistine 2HCl","e11","L1300-11","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017,IP2010",null,"Neurological Disease","Histamine Receptor","Neuronal Signaling","Betahistine (PT-9) is a histamine H3 receptor inhibitor with IC50 of 1.9 μM.",209.12,"5579-84-0",38,181.71,38,181.71,"http://selleckchem.com/products/betahistine-dihydrochloride.html","C8H12N2.2HCl","2HCl","PT-9","Cl.Cl.CNCCC1=NC=CC=C1",1.444,1,1,3]
["S3178","Brinzolamide","f11","L1300-11","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","020816","Inflammation/Ophthalmology","Carbonic Anhydrase","Metabolism","Brinzolamide (AL-4862) is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM.",383.51,"138890-62-7",77,200.78,"<1",0,"http://selleckchem.com/products/brinzolamide.html","C12H21N3O5S3","free base","AL-4862","CCNC1CN(CCCOC)[S](=O)(=O)C2=C1C=C(S2)[S](N)(=O)=O",-0.772,5,2,7]
["S3179","Carbenicillin disodium","g11","L1300-11","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia,USP39-NF34,IP2010","050306,050298","Infection","Antibiotics,Antibiotics for Plant Cell Culture,Bacterial,Selection Antibiotics for Transfected Cell","Microbiology","Carbenicillin (BRL-2064,α-carboxybenzylpenicillin) is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity.",422.36,"4800-94-6",5,11.84,84,198.88,"http://selleckchem.com/products/carbenicillin-disodium.html","C17H16N2Na2O6S","Disodium","BRL-2064,α-carboxybenzylpenicillin","[Na+].[Na+].CC1(C)SC2C(NC(=O)C(C([O-])=O)C3=CC=CC=C3)C(=O)N2C1C([O-])=O",-2.218,2,1,5]
["S3180","Eletriptan HBr","h11","L1300-11","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia","201536,202040,205152,205186,206409,206787,210708","Neurological Disease","5-HT Receptor","Neuronal Signaling","Eletriptan (UK-116044) is a selective 5-HT1B and 5-HT1D receptor agonist with Ki of 0.92 nM and 3.14 nM, respectively.",463.43,"177834-92-3",93,200.68,"<1",0,"http://selleckchem.com/products/eletriptan-hydrobromide.html","C22H26N2O2S.HBr","HBr","UK-116044","Br.CN1CCCC1CC2=C[NH]C3=C2C=C(CC[S](=O)(=O)C4=CC=CC=C4)C=C3",4.929,2,1,6]
["S3181","Flumequine","a2","L1300-12","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.2,BP2017",null,"Infection","Topoisomerase","DNA Damage/DNA Repair","Flumequine(R-802) is a synthetic chemotherapeutic antibiotic, inhibiting topoisomerase II with IC50 of 15 μM.",261.25,"42835-25-6",3,11.48,"<1",0,"http://selleckchem.com/products/flumequine.html","C14H12FNO3","free base","R-802","CC1CCC2=C3N1C=C(C(O)=O)C(=O)C3=CC(=C2)F",2.27,2,0,1]
["S3183","Amitriptyline HCl","b2","L1300-12","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","040218,040816,085031,085032,085594,085627,085742,085743,085744,085745,085815,085816,085817,085819,085820,085821,085836,085864,085922,085923,085925,085926,085927,085935,085936,085944,085945,085966,085967,085968,085969,085970,085971,086002,086003,086004,086009,086010,086011,086090,086143,086144,086145,086146,086147,086148,086153,086157,086158,086335,086336,086337,086610,086743,086744,086745,086746,086747,086853,086854,086857,086859,086860,087181,087278,087366,087367,087368,087369,087370,087557,087616,087617,087632,087639,087647,087775,088075,088076,088077,088078,088079,088084,088085,088105,088106,088107,088421,088422,088423,088424,088425,088426,088620,088621,088622,088633,088634,088635,088672,088673,088674,088675,088697,088698,088699,088700,088701,088702,088853,088854,088855,088856,088857,088883,088884,088885,088886,088887,088888,089399,089400,089402,089423,202446,210086","Neurological Disease/Psychotic disorders","5-HT Receptor,Histamine Receptor,Serotonin Transporter","Neuronal Signaling","Amitriptyline HCl is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline HCl also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. Amitriptyline is a tricyclic antidepressant (TCA).",313.86,"549-18-8",63,200.73,15,47.79,"http://selleckchem.com/products/amitriptyline-hydrochloride.html","C20H23N.HCl","HCl","N/A","Cl.CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C13",5.154,0,0,3]
["S3185","Adrenalone HCl","c2","L1300-12","in 10mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017",null,"Angiology","Adrenergic Receptor","Neuronal Signaling","Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic, mainly acts on alpha-1 adrenergic receptors.",217.65,"62-13-5",44,202.16,44,202.16,"http://selleckchem.com/products/adrenalone-hcl.html","C9H11NO3.HCl","HCl","N/A","Cl.CNCC(=O)C1=CC(=C(O)C=C1)O",0.938,1,3,3]
["S3186","Azatadine dimaleate","d2","L1300-12","in 10mM DMSO","EMA","Martindale:The Extra Pharmacopoeia,USP42-NF37",null,"Immunology/Inflammation","Histamine Receptor","Neuronal Signaling","Azatadine (SCH10649,Azatadine Maleate) is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively.",522.55,"3978-86-7",105,200.94,105,200.94,"http://selleckchem.com/products/azatadine-dimaleate.html","C20H22N2.2C4H4O4","Dimaleate","SCH10649,Azatadine Maleate","CN1CCC(CC1)=C2C3=CC=CC=C3CCC4=CC=CN=C24.OC(=O)\\C=C/C(O)=O.OC(=O)\\C=C/C(O)=O",1.128,5,0,4]
["S3189","Ropinirole HCl","e2","L1300-12","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,BP2017","077460,077852,078110,078230,078881,079050,079165,079229,090135,090411,090429,090869,091395,200431,200462,201047,201576,202786,204022","Neurological Disease","Dopamine Receptor","Neuronal Signaling","Ropinirole (SKF-101468A) a selective dopamine D2 receptors agonist with Ki of 29 nM.",296.84,"91374-20-8",10,33.69,60,202.13,"http://selleckchem.com/products/ropinirole-hydrochloride.html","C16H24N2O.HCl","HCl","SKF-101468A","Cl.CCCN(CCC)CCC1=CC=CC2=C1CC(=O)N2",3.341,1,1,7]
["S3193","Ticarcillin sodium","f2","L1300-12","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,BP2017,USP39-NF34",null,"Infection","Antibiotics,Bacterial,Selection Antibiotics for Transfected Cell","Microbiology","Ticarcillin (AB 2288, BRL 2288) is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria.",430.41,"29457-07-6",86,199.81,86,199.81,"http://selleckchem.com/products/ticarcillin-sodium.html","C15H16N2O6S2.2Na","Sodium","AB 2288, BRL 2288","[NaH].[NaH].CC1(C)SC2C(NC(=O)C(C(O)=O)C3=CSC=C3)C(=O)N2C1C(O)=O",0.392,4,1,5]
["S3195","Azlocillin sodium salt","g2","L1300-12","in 10mM DMSO","FDA,CFDA","Martindale:The Extra Pharmacopoeia","050562,062388,062417","Infection","Bacterial","Microbiology","Azlocillin is an acylampicillin with a broad spectrum against bacteria.",484.48,"37091-65-9",97,200.21,97,200.21,"http://selleckchem.com/products/azlocillin-sodium-salt.html","C20H23N5O6S.Na","Sodium Salt","N/A","[NaH].CC1(C)SC2C(NC(=O)C(NC(=O)N3CCNC3=O)C4=CC=CC=C4)C(=O)N2C1C(O)=O",0.004,5,3,5]
["S3199","Reboxetine mesylate","h2","L1300-12","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Psychotic disorders","Others","Endocrinology & Hormones","Reboxetine (PNU 155950E) is a norepinephrine reuptake inhibitor with Ki of 8.2 nM.",409.5,"98769-84-7",82,200.24,82,200.24,"http://selleckchem.com/products/reboxetine-mesylate.html","C19H23NO3.CH4O3S","Mesylate","PNU 155950E, FCE20124 mesylate","CCOC1=C(OC(C2CNCCO2)C3=CC=CC=C3)C=CC=C1.C[S](O)(=O)=O",2.663,3,1,6]
["S3200","Triflusal","a3","L1300-12","in 10mM DMSO",null,"BP2019;EP9.2;KP Ⅹ",null,"Cardiovascular Disease","COX","Immunology & Inflammation","Triflusal (UR1501) irreversibly inhibits the production of thromboxane-B2 in platelets by acetylating cycloxygenase-1.",248.16,"322-79-2",50,201.48,"<1",0,"http://selleckchem.com/products/triflusal.html","C10H7F3O4","free base","UR1501","CC(=O)OC1=CC(=CC=C1C(O)=O)C(F)(F)F",2.169,3,0,4]
["S3201","Trifluoperazine 2HCl","b3","L1300-12","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","089893","Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Trifluoperazine (NSC-17474, RP-7623, SKF-5019) 2HCl is a dopamine D2 receptor inhibitor with IC50 of 1.1 nM. Trifluoperazine also inhibits calmodulin (CaM).",480.42,"440-17-5",88,183.17,96,199.83,"http://selleckchem.com/products/trifluoperazine-dihydrochloride.html","C21H24F3N3S.2HCl","2HCl","SKF5019","Cl.Cl.CN1CCN(CCCN2C3=C(SC4=CC=C(C=C24)C(F)(F)F)C=CC=C3)CC1",5.739,0,0,5]
["S3207","Iopromide","d3","L1300-12","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,BP2017","040153,040209,085785,085786,085787,085788,085789,085973,085975,085976,087328,087612,087613,087614,088143,088710,088967,088968,088969,088970","Diagnosis","Others","Others","Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. It functions as a contrast agent by opacifying blood vessels in the path of flow of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs.",791.11,"73334-07-3",100,126.4,100,126.4,"http://selleckchem.com/products/iopromide.html","C18H24I3N3O8","free base","N/A","COCC(=O)NC1=C(I)C(=C(I)C(=C1I)C(=O)N(C)CC(O)CO)C(=O)NCC(O)CO",-1.057,4,6,11]
["S3208","Fexofenadine HCl","e3","L1300-12","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017,IP2010","076169,076191,076447,076502,076707,076970,077081,201311","Immunology/Inflammation","Histamine Receptor","Neuronal Signaling","Fexofenadine (MDL 16455A) inhibits histamine H1 receptor with IC50 of 246 nM.",538.12,"153439-40-8",107,198.84,2,3.72,"http://selleckchem.com/products/fexofenadine-hcl.html","C32H39NO4.HCl","HCl","MDL 16455A","Cl.CC(C)(C(O)=O)C1=CC=C(C=C1)C(O)CCCN2CCC(CC2)C(O)(C3=CC=CC=C3)C4=CC=CC=C4",2.989,1,1,10]
["S3212","Moclobemide (Ro 111163)","f3","L1300-12","in 10mM DMSO","CFDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005",null,"Psychotic disorders","MAO","Metabolism","Moclobemide is a MAO-A (5-HT) inhibitor with IC50 of 6.1 μM.",268.74,"71320-77-9",53,197.22,"<1",0,"http://selleckchem.com/products/moclobemide.html","C13H17ClN2O2","free base","N/A","ClC1=CC=C(C=C1)C(=O)NCCN2CCOCC2",1.528,2,1,4]
["S3604","Triptolide (PG490)","g3","L1300-12","in 10mM DMSO","CFDA",null,null,"Cancer","ADC Cytotoxin,Apoptosis related,HSP (HSP90),MDM2/MDMX,NF-κB","NF-κB","Triptolide (PG490, NSC 163062) is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It functions as a NF-κB inhibitor with dual actions by disruption of p65/CBP interaction and by reduction of p65 protein. Triptolide (PG490) abrogates the transactivation function of heat shock transcription factor 1 (HSF1). Triptolide inhibits MDM2 and induces apoptosis through a p53-independent pathway.",360.4,"38748-32-2",72,199.78,"<1",0,"http://selleckchem.com/products/triptolide.html","C20H24O6","free base","NSC 163062","CC(C)C12OC1C3OC34C5(C)CCC6=C(COC6=O)C5CC7OC47C2O",0.872,5,1,1]
["S3606","Fangchinoline","h3","L1300-12","in 10mM DMSO",null,"CP2005",null,"Cancer","Reverse Transcriptase","Microbiology","Fangchinoline, a bisbenzylisoquinoline alkaloid, is a novel HIV-1 inhibitor with pain-relieving, blood pressure-depressing, and antibiotic activities.",608.72,"33889-68-8",100,164.28,"<1",0,"http://selleckchem.com/products/r-s-fangchinoline.html","C37H40N2O6","free base","N/A","COC1=C2OC3=CC=C(CC4N(C)CCC5=C4C=C(OC6=C(O)C(=CC7=C6C(CC(=C2)C=C1)N(C)CC7)OC)C(=C5)OC)C=C3",6.992,5,1,3]
["S3609","Berbamine dihydrochloride","a4","L1300-12","in 10mM DMSO","CFDA",null,null,"Hematology","Bcr-Abl,CaMK,NF-κB","Angiogenesis","Berbamine (BA, BBM) dihydrochloride, a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan), is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF-κB. Berbamine (BA, BBM) dihydrochloride induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca²⁺/calmodulin-dependent protein kinase II (CaMKII).",681.65,"6078-17-7",100,146.7,100,146.7,"http://selleckchem.com/products/berbamine-dihydrochloride.html","C37H40N2O6.2HCl","dihydrochloride","BA, BBM","Cl.Cl.COC1=CC2=C3C=C1OC4=C(OC)C(=CC5=C4C(CC6=CC(=C(O)C=C6)OC7=CC=C(CC3N(C)CC2)C=C7)N(C)CC5)OC",7.756,5,1,3]
["S3611","(+)-Fangchinoline","b4","L1300-12","in 10mM DMSO",null,"CP2005",null,"Cancer","Others","Others","Fangchinoline ((+)-Limacine, Tetrandrine B, Hanfangichin B) is a phytochemical that has been shown to elicit anti-cancer effects in prostate and breast cancer cell lines via inducing G1 cell cycle arrest. It has also been shown to possess neuroprotective activity.",608.72,"436-77-1",40,65.71,"<1",0,"http://selleckchem.com/products/s-s-fangchinoline.html","C37H40N2O6","free base","(+)-Limacine, Tetrandrine B, Hanfangichin B","COC1=C2OC3=CC=C(CC4N(C)CCC5=C4C=C(OC6=C7C(CC(=C2)C=C1)N(C)CCC7=CC(=C6O)OC)C(=C5)OC)C=C3",6.992,5,1,3]
["S3612","Rosmarinic acid","c4","L1300-12","in 10mM DMSO","DMF","EP9.1,BP2017",null,"Cancer/Cardiovascular Disease/Infection/Inflammation","Complement System,IκB/IKK","NF-κB","Rosmarinic acid (RA, Rosemary acid) is a naturally occurring hydroxylated compound. It has the ability to block complement fixation, inhibit lipoxygenase and cyclooxygenase activity and inhibit the expression of CCL11 and CCR3 by suppressing the IKK-β activity in NF-κB activation signaling.",360.31,"20283-92-5",72,199.83,24,66.61,"http://selleckchem.com/products/rosmarinic-acid.html","C18H16O8","free base","Rosemary acid","OC(=O)C(CC1=CC=C(O)C(=C1)O)OC(=O)\\C=C\\C2=CC=C(O)C(=C2)O",2.706,3,4,7]
["S3615","Dehydrocostus Lactone","d4","L1300-12","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cardiovascular Disease/Gastroenterology/Infection","IκB/IKK","NF-κB","Dehydrocostus lactone (DHE), a natural sesquiterpene lactone, inhibits IKKβ activity, IκBα phosphorylation and degradation, coactivators p300 recruitments and p50/p65 NF-κB nuclear translocation, and their DNA binding activity on COX-2 promoter. It has anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.",230.3,"477-43-0",46,199.74,"<1",0,"http://selleckchem.com/products/dehydrocostus-lactone.html","C15H18O2","free base","N/A","C=C1CCC2C(OC(=O)C2=C)C3C1CCC3=C",3.282,2,0,0]
["S3616","Asiaticoside","e4","L1300-12","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Cancer","ROS","Immunology & Inflammation","Asiaticoside (Ba 2742, BRN0078195, CCRIS8995, NSC166062, Emdecassol,Madecassol), the major active principle of Centella asiatica, prevents ultraviolet A-dependent photoaging by suppressing ultraviolet A-induced reactive oxygen species production. It also decreases DNA binding by MITF.",959.12,"16830-15-2",100,104.26,"<1",0,"http://selleckchem.com/products/asiaticoside.html","C48H78O19","free base","Ba 2742, BRN0078195, CCRIS8995, NSC166062, Emdecassol,Madecassol","CC1CCC2(CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(CO)C5CCC34C)C2C1C)C(=O)OC6OC(COC7OC(CO)C(OC8OC(C)C(O)C(O)C8O)C(O)C7O)C(O)C(O)C6O",-0.101,7,12,10]
["S3618","Acetylspiramycin (ASPM)","f4","L1300-12","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Infection","Anti-infection","Microbiology","Acetylspiramycin (ASPM, Spiramycin II, Foromacidin B) is a macrolide antimicrobial agent.",885.09,"24916-51-6",100,112.98,"<1",0,"http://selleckchem.com/products/acetylspiramycin.html","C45H76N2O15","free base","Spiramycin II, Foromacidin B","COC1C(CC(=O)OC(C)C/C=C/C=C/C(OC2CCC(C(C)O2)N(C)C)C(C)CC(CC=O)C1OC3OC(C)C(OC4CC(C)(O)C(O)C(C)O4)C(C3O)N(C)C)OC(C)=O",2.428,12,2,13]
["S3621","Pazufloxacin mesylate","g4","L1300-12","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Infection","Bacterial","Microbiology","Pazufloxacin Mesylate (T-3762, Pazucross), also known as Pazucross and T-3762, is a quinolone antibacterial agent used for the intravenous therapy of several infections.",414.41,"163680-77-1",82,197.87,82,197.87,"http://selleckchem.com/products/pazufloxacin-mesylate.html","C16H15FN2O4.CH4O3S","methanesulfonate","T-3762, Pazucross","CC1COC2=C(C(=CC3=C2N1C=C(C(O)=O)C3=O)F)C4(N)CC4.C[S](O)(=O)=O",-1.899,3,1,2]
["S3622","Diammonium Glycyrrhizinate","h4","L1300-12","in 10mM DMSO","CFDA",null,null,"Infection/Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Diammonium glycyrrhizinate (DG), a traditional Chinese medicine (TCM), is extracted and purified from liquorices (Radix glycyrrhizae). It is known for its anti-inflammatory effects, resistance to biologic oxidation and membranous protection. DG is able to reduce inflammatory injury via suppression of NF‑κB, TNF‑α and intercellular adhesion molecule 1.",856.99,"79165-06-3",100,116.69,100,116.69,"http://selleckchem.com/products/diammonium-glycyrrhizinate.html","C42H62O16.2H3N","ammonium salt","N/A","N.N.CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O)OC6OC(C(O)C(O)C6OC7OC(C(O)C(O)C7O)C(O)=O)C(O)=O",-4.247,8,5,7]
["S3623","Ceftibuten dihydrate","a5","L1300-12","in 10mM DMSO","FDA,NDC","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17","050685,050686","Infection/Inflammation","Bacterial","Microbiology","Ceftibuten Dihydrate(Sch-39720 dihydrate) is the dihydrate form of ceftibuten, a semisynthetic, beta-lactamase-stable, third-generation cephalosporin with antibacterial activity.",446.46,"118081-34-8",89,199.35,"<1",0,"https://www.selleckchem.com/products/ceftibuten-dihydrate.html","C15H18N4O8S2",0,"Sch-39720 dihydrate","O.O.NC1=NC(=CS1)C(=C/CC(O)=O)/C(=O)NC2C3SCC=C(N3C2=O)C(O)=O",-0.958,5,2,6]
["S3625","Tyramine","b5","L1300-12","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017",null,"Cardiovascular Disease/Neurological Disease","TAAR","GPCR & G Protein","Tyramine (4-hydroxyphenethylamine, para-tyramine, mydrial, uteramin) is a naturally occurring trace amine derived from the amino acid tyrosine and acts as a catecholamine releasing agent.",137.18,"51-67-2",27,196.82,"<1",0,"http://selleckchem.com/products/tyramine.html","C8H11NO","free base","4-hydroxyphenethylamine, para-tyramine, mydrial, uteramin","NCCC1=CC=C(O)C=C1",1.015,0,2,2]
["S3627","Tryptamine","c5","L1300-12","in 10mM DMSO",null,"USP43-NF38",null,"Neurological Disease","TAAR","GPCR & G Protein","Tryptamine is a monoamine alkaloid and may play a role as a neuromodulator or neurotransmitter. It is an agonist of hTAAR1. It acts as a non-selective serotonin receptor agonist and serotonin-norepinephrine-dopamine releasing agent (SNDRA).",160.22,"61-54-1",32,199.73,"<1",0,"http://selleckchem.com/products/tryptamine.html","C10H12N2","free base","N/A","NCCC1=C[NH]C2=CC=CC=C12",1.55,0,2,2]
["S3635","Medroxyprogesterone","d5","L1300-12","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","040159,040311,076552,076553,077235,077334,078711,088484,210227,210335,210760,210761","Cancer/Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Medroxyprogesterone (MP) is a synthetic pregnane steroid and a derivative of progesterone. It is a potent progesterone receptor agonist.",344.49,"520-85-4",68,197.39,"<1",0,"http://selleckchem.com/products/medroxyprogesterone.html","C22H32O3","free base","MP","CC1CC2C(CCC3(C)C2CCC3(O)C(C)=O)C4(C)CCC(=O)C=C14",3.376,2,0,1]
["S3637","Cefpirome sulfate","e5","L1300-12","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Infection","Bacterial","Microbiology","Cefpirome(HR-810 sulfate) is a fourth-generation cephalosporin and is considered highly active against Gram-negative bacteria.",612.66,"98753-19-6",100,163.22,100,163.22,"http://selleckchem.com/products/cefpirome-sulfate.html","C22H23N6O5S2.HO4S","sulfate","HR-810 sulfate","CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)C[N+]3=CC=CC4=C3CCC4)C5=CSC(=N5)N.O[S](O)(=O)=O",-0.65,5,2,7]
["S3638","Cefamandole nafate","f5","L1300-12","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,BP2017,IP2010","050504,062560","Infection","Bacterial","Microbiology","Cefamandole Nafate is the sodium salt form of cefamandole formyl ester. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall, interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.",512.49,"42540-40-9",100,195.13,100,195.13,"http://selleckchem.com/products/cefamandole-nafate.html","C19H17N6O6S2.Na","sodium salt","N/A","[Na+].C[N]1N=NN=C1SCC2=C(N3C(SC2)C(NC(=O)C(OC=O)C4=CC=CC=C4)C3=O)C([O-])=O",-1.169,6,1,9]
["S3639","Tacrine hydrochloride hydrate","g5","L1300-12","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP39-NF34","020070","Neurological Disease","AChR,HNMT","Neuronal Signaling","Tacrine (Tetrahydroaminacrine, Tetrahydroaminoacridine) is a centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. It also acts as a histamine N-methyltransferase inhibitor.","198.26(free bases)","206658-92-6",50,252.19,50,252.19,"http://selleckchem.com/products/tacrine-hydrochloride-hydrate.html","C13H14N2.xHCl.xH2O","hydrochloride hydrate","Tacrine, Tetrahydroaminacrine, Tetrahydroaminoacridine","NC1=C2C=CC=CC2=NC3=C1CCCC3",4.258,1,1,0]
["S3640","Methoxyphenamine Hydrochloride","h5","L1300-12","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Immunology","Adrenergic Receptor","Neuronal Signaling","Methoxyphenamine Hydrochloride (2-methoxy-N-methylamphetamine, OMMA) is a β-adrenergic receptor agonist of the amphetamine class used as a bronchodilator.",215.72,"5588-10-3",43,199.33,43,199.33,"http://selleckchem.com/products/methoxyphenamine-hydrochloride.html","C11H17N.HCl","hydrochloride","2-methoxy-N-methylamphetamine Hydrochloride, OMMA Hydrochloride","Cl.CNC(C)CC1=CC=CC=C1OC",2.431,1,1,4]
["S3641","Osalmid","a6","L1300-12","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Inflammation/Gastrointestinal Disease","DNA/RNA Synthesis,RNR","DNA Damage/DNA Repair","Osalmid suppresses ribonucleotide reductase (RNR) activity in a concentration-dependent manner, with a 50% RR activity-inhibitory concentration (IC50) of 8.23 μM.",229.23,"526-18-1",45,196.31,"<1",0,"http://selleckchem.com/products/osalmid.html","C13H11NO3","free base","N/A","OC1=CC=C(NC(=O)C2=C(O)C=CC=C2)C=C1",2.13,1,3,2]
["S3643","Amitraz","b6","L1300-12","in 10mM DMSO",null,"USP38-NF33;BP2013;IP2010",null,"Infection/Parasitology","Adrenergic Receptor","Neuronal Signaling","Amitraz (NSC 324552) is a triazapentadiene, an α2 adrenergic agonist and a member of the amidine chemical family. It is a non-systemic acaricide and insecticide.",293.41,"33089-61-1",58,197.68,"<1",0,"http://selleckchem.com/products/amitraz.html","C19H23N3","free base","NSC 324552","CN(C=NC1=CC=C(C)C=C1C)C=NC2=CC=C(C)C=C2C",4.825,2,0,4]
["S3644","Sulfamonomethoxine","c6","L1300-12","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Infection/Inflammation","Bacterial","Microbiology","Sulfamonomethoxine is a long-acting sulfonamide antibacterial agent and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.",280.3,"1220-83-3",56,199.79,"<1",0,"http://selleckchem.com/products/sulfamonomethoxine.html","C11H12N4O3S","free base","N/A","COC1=NC=NC(=C1)N[S](=O)(=O)C2=CC=C(N)C=C2",0.854,5,2,4]
["S3645","Kitasamycin","d6","L1300-12","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,CP2005,KP Ⅹ,JP17",null,"Infection","Antibiotics","Microbiology","Kitasamycin (Leucomycin) is a macrolide antibiotic. It has antimicrobial activity against a wide spectrum of pathogens.",785.96,"1392-21-8",100,127.23,"<1",0,"http://selleckchem.com/products/kitasamycin.html","C40H67NO14","free base","leucomycin","COC1C(O)CC(=O)OC(C)C/C=C/C=C/C(O)C(C)CC(CC=O)C1OC2OC(C)C(OC3CC(C)(O)C(OC(=O)CC(C)C)C(C)O3)C(C2O)N(C)C",2.578,10,3,12]
["S3647","Mafenide Acetate","e6","L1300-12","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","201511,206716","Infection","Carbonic Anhydrase","Metabolism","Mafenide Acetate is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.",246.28,"13009-99-9",49,198.96,49,198.96,"http://selleckchem.com/products/mafenide-acetate.html","C7H10N2O2S.C2H4O2","acetate","N/A","CC(O)=O.NCC1=CC=C(C=C1)[S](N)(=O)=O",-3.043,3,2,2]
["S3648","Amlexanox (AA-673)","f6","L1300-12","in 10mM DMSO","FDA,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,JP17","021727","Immunology/Inflammation","Immunology & Inflammation related,IκB/IKK,TBK1","Immunology & Inflammation","Amlexanox (AA-673, CHX-3673, Amoxanox) is an anti-inflammatory antiallergic immunomodulator and also an inhibitor of the protein kinases TBK1 and IKK-ε.",298.29,"68302-57-8",59,197.79,"<1",0,"http://selleckchem.com/products/amlexanox.html","C16H14N2O4","free base","CHX-3673, Amoxanox","CC(C)C1=CC2=C(OC3=NC(=C(C=C3C2=O)C(O)=O)N)C=C1",2.969,4,1,2]
["S3654","Tauroursodeoxycholic Acid (TUDCA)","g6","L1300-12","in 10mM DMSO","DMF",null,null,"Gastroenterology","Mitochondrial Metabolism","Neuronal Signaling","Tauroursodeoxycholic acid (TUDCA) is the taurine conjugate of ursodeoxycholic acid (UDCA) and acts as a mitochondrial stabilizer and anti-apoptotic agent in several models of neurodegenerative diseases, including AD, Parkinson's diseases (PD), and Huntington's diseases (HD).",499.7,"14605-22-2",99,198.12,30,60.04,"http://selleckchem.com/products/tauroursodeoxycholic-acid.html","C26H45NO6S","free base","N/A","CC(CCC(=O)NCC[S](O)(=O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C",2.997,1,3,7]
["S3655","Cefepime Dihydrochloride Monohydrate","h6","L1300-12","in 10mM DMSO","CFDA,PMDA,HMA","EP9.2,BP2015",null,"Infection","Bacterial","Microbiology","Cefepime is a cephalosporin antibacterial drug used to treat pneumonia, urinary tract, skin, and intra-abdominal infections.",571.5,"123171-59-5",100,174.98,1,1.75,"http://selleckchem.com/products/cefepime-dihydrochloride-monohydrate.html","C19H25N6O5S2.HCl.Cl.H2O","dihydrochloride hydrate","N/A","O.Cl.Cl.CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)C[N+]3(C)CCCC3)C4=CSC(=N4)N",-2.421,5,2,7]
["S3656","Piribedil","a7","L1300-12","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Adrenergic Receptor,Dopamine Receptor","Neuronal Signaling","Piribedil (Trivastal, Trivastan) is a relatively selective dopamine (D2/D3) agonist with moderate antidepressant activity. It also has α2-adrenergic (α2A/α2C) antagonist properties.",298.34,"3605-01-4",59,197.76,"<1",0,"http://selleckchem.com/products/piribedil.html","C16H18N4O2","free base","Trivastal, Trivastan","C1OC2=CC=C(CN3CCN(CC3)C4=NC=CC=N4)C=C2O1",2.043,4,0,3]
["S3657","Promestriene","b7","L1300-12","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia",null,"Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Promestriene (3-propyl ethyl, 17B-methyl estradiol) is a synthetic estrogen analog that has been reported to significantly improve the symptoms of vaginal atrophy caused by estrogen deprivation in topical application.",328.49,"39219-28-8",65,197.88,3,9.13,"http://selleckchem.com/products/promestriene.html","C22H32O2","free base","3-propyl ethyl, 17B-methyl estradiol","CCCOC1=CC2=C(C=C1)C3CCC4(C)C(CCC4C3CC2)OC",5.344,2,0,4]
["S3659","Fludrocortisone acetate","c7","L1300-12","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,IP2010","040425,040431,091302","Endocrinology","Others","Others","Fludrocortisone (9α-fluorocortisol) is a synthetic pregnane steroid and a halogenated derivative of cortisol. It is used to treat adrenogenital syndrome, postural hypotension, and adrenal insufficiency.",422.49,"514-36-3",84,198.82,"<1",0,"http://selleckchem.com/products/fludrocortisone-acetate.html","C23H31FO6","free base","9α-fluorocortisol acetate","CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3(F)C(O)CC12C",1.791,4,1,4]
["S3663","Afloqualone","d7","L1300-12","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Neurological Disease","GABA Receptor","Neuronal Signaling","Afloqualone (AFQ, HQ-495) is a quinazolinone family GABAergic drug with muscle-relaxant and sedative effects, showing the agonist activity at the β subtype of the GABAa receptor.",283.3,"56287-74-2",56,197.67,"<1",0,"http://selleckchem.com/products/afloqualone.html","C16H14FN3O","free base","HQ-495","CC1=C(C=CC=C1)N2C(=O)C3=C(C=CC(=C3)N)N=C2CF",2.619,2,1,2]
["S3666","Ilaprazole","e7","L1300-12","in 10mM DMSO","CFDA",null,null,"Gastrointestinal Disease","ATPase,Proton Pump","Transmembrane Transporters","Ilaprazole (IY-81149) is a new proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. It inhibits H+/K+-ATPase with an IC50 of 6.0 μM.",366.44,"172152-36-2",73,199.21,"<1",0,"http://selleckchem.com/products/ilaprazole.html","C19H18N4O2S","free base","IY-81149","COC1=CC=NC(=C1C)C[S](=O)C2=NC3=C([NH]2)C=C(C=C3)[N]4C=CC=C4",3.311,4,1,5]
["S3668","Thymopentin","f7","L1300-12","in 10mM DMSO","DMF,CFDA",null,null,"Cancer/Infection","Immunology & Inflammation related","Immunology & Inflammation","Thymopentin (TP5) has immuno-regulatory activities. The immuno-regulatory actions of thymopentin on peripheral T cells are mediated by intracellular cyclic GMP elevations in contrast to the intracellular cyclic AMP elevations induced in precursor T cells that trigger their further differentiation to T cells.",679.77,"69558-55-0",100,147.11,100,147.11,"http://selleckchem.com/products/thymopentin.html","C30H49N9O9","free base","TP5","CC(C)C(NC(=O)C(CC(O)=O)NC(=O)C(CCCCN)NC(=O)C(N)CCCNC(N)=N)C(=O)NC(CC1=CC=C(O)C=C1)C(O)=O",-6.675,6,9,23]
["S3669","Carmustine","g7","L1300-12","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","209278,210179,211229","Cancer","DNA/RNA Synthesis","DNA Damage/DNA Repair","Carmustine (bis-chloroethylnitrosourea, BCNU, BiCNU) is a cell-cycle phase nonspecific alkylating antineoplastic agent and used in the treatment of brain tumors and various other malignant neoplasms.",214.05,"154-93-8","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/carmustine.html","C5H9Cl2N3O2","free base","bis-chloroethylnitrosourea, BCNU, BiCNU","ClCCNC(=O)N(CCCl)N=O",1.201,2,1,5]
["S3671","Quinestrol","h7","L1300-12","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia","016768","Cancer/Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Quinestrol (Ethinylestradiol 3-cyclopentyl ether, EE2CPE, W-3566) is a synthetic, steroidal estrogen which is used in hormone replacement therapy and occasionally to treat breast cancer and prostate cancer.",364.52,"152-43-2",72,197.52,"<1",0,"http://selleckchem.com/products/quinestrol.html","C25H32O2","free base","Ethinylestradiol 3-cyclopentyl ether, EE2CPE, W-3566","CC12CCC3C(CCC4=C3C=CC(=C4)OC5CCCC5)C1CCC2(O)C#C",6.514,1,0,2]
["S3672","Cefonicid sodium","a8","L1300-12","in 10mM DMSO","FDA,CFDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,USP39-NF34","050579,063295","Infection","Antibiotics,Bacterial","Microbiology","Cefonicid sodium (Monocid) is a cephalosporin antibiotic. It interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism.",586.53,"61270-78-8",100,170.49,100,170.49,"http://selleckchem.com/products/cefonicid-sodium.html","C18H16N6O8S3.2Na","disodium salt","Monocid sodium","[Na+].[Na+].OC(C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)CSC3=NN=N[N]3C[S]([O-])(=O)=O)C4=CC=CC=C4",-4.327,5,2,9]
["S3673","Sulfaphenazole","b8","L1300-12","in 10mM DMSO","FDA",null,"013092,013093","Infection","P450 (e.g. CYP17)","Metabolism","Sulfaphenazole (Depocid, Depotsulfonamide, Plisulfan, Raziosulfa) is an inhibitor of CYP2C9 with Ki value of 0.3 μM and demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki values of 63 and 29 μM for CYP2C8 and CYP2C18, respectively, and no activity at CYP1A1, CYP1A2, CYP3A4, CYP2C19).",314.36,"526-08-9",62,197.23,"<1",0,"http://selleckchem.com/products/sulfaphenazole.html","C15H14N4O2S","free base","Depocid, Depotsulfonamide, Plisulfan, Raziosulfa","NC1=CC=C(C=C1)[S](=O)(=O)NC2=CC=N[N]2C3=CC=CC=C3",1.922,3,2,4]
["S3674","Levamlodipine","c8","L1300-12","in 10mM DMSO","CFDA",null,null,"Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Levamlodipine (S-amlodipine) is a pharmacologically active enantiomer of amlodipine which belongs to the dihydropyridine group of calcium channel blocker. It acts on the L-type of calcium channels and its treatment results in vasodilation and a fall in blood pressure.",408.88,"103129-82-4",81,198.1,81,198.1,"http://selleckchem.com/products/levamlodipine.html","C20H25ClN2O5","free base","S-amlodipine","CCOC(=O)C1=C(COCCN)NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C",1.576,5,2,10]
["S3675","Umbelliferone","d8","L1300-12","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cardiovascular Disease/Infection","Immunology & Inflammation related","Immunology & Inflammation","Umbelliferone (7-hydroxycoumarin, hydrangine, skimmetine, beta-umbelliferone) is a 7-hydroxycoumarin that is a pharmacologically active agent. It is a fluorescing compound used as a sunscreen agent and shows good inhibitions of DPPH, hydroxyl, superoxide anion and ABTS radicals with anti-inflammatory, anti-hyperglycaemic, molluscicidal and anti-tumor activities.",162.14,"93-35-6",32,197.36,"<1",0,"http://selleckchem.com/products/umbelliferone.html","C9H6O3","free base","7-hydroxycoumarin, hydrangine, skimmetine, beta-umbelliferone","OC1=CC2=C(C=C1)C=CC(=O)O2",1.657,2,1,0]
["S3676","Carbendazim","e8","L1300-12","in 10mM DMSO","CFDA",null,null,"Cancer","Fungal","Microbiology","Carbendazim (Mercarzole, Carbendazole) is a broad-spectrum systemic antimycotic and can be used to control a broad range of diseases on field crops, fruits, and vegetables, including sclerotinia rot of canola, wheat head blight, peanut leaf spot, and SB on rice. Its mode of action is to inhibit the formation of mitotic microtubules in of fungi.",191.19,"10605-21-7",17,88.92,"<1",0,"http://selleckchem.com/products/carbendazim.html","C9H9N3O2","free base","Mercarzole, Carbendazole","COC(=O)NC1=NC2=C([NH]1)C=CC=C2",1.65,3,2,2]
["S3677","Cinnamic acid","f8","L1300-12","in 10mM DMSO","NDC","Martindale:The Extra Pharmacopoeia,BP2017,EP9.1",null,"Cancer/Cardiovascular Disease/Neurological Disease/Respiratory Disease","Others","Others","Cinnamic acid (Benzenepropenoic acid, Isocinnamic acid, trans-Cinnamic acid, Phenylacrylic acid), a naturally occurring aromatic fatty acid of low toxicity, induces cytostasis and a reversal of malignant properties of human tumor cells in vitro.",148.16,"140-10-3",29,195.73,"<1",0,"http://selleckchem.com/products/cinnamic-acid.html","C9H8O2","free base","trans-Cinnamic acid, Phenylacrylic acid, Cinnamylic acid, 3-Phenylacrylic acid|(E)-Cinnamic acid, Benzenepropenoic acid, Isocinnamic acid","OC(=O)/C=C/C1=CC=CC=C1",1.927,1,0,2]
["S3681","Vitamin E Acetate","g8","L1300-12","in 10mM DMSO","DMF","IP2010",null,"Cardiovascular Disease/Endocrinology","Vitamin","Metabolism","Vitamin E Acetate (Tocopherol) is the stable form of Vitamin E most often used in cosmetic formulations for its skin care benefits. It protects the cells against free radicals and prevents the peroxidation of body fats as an in-vivo antioxidant., Vitamin E Acetate (Tocopherol) is the stable form of Vitamin E most often used in cosmetic formulations for its skin care benefits. It protects the cells against free radicals and prevents the peroxidation of body fats as an in-vivo antioxidant. ,",472.74,"58-95-7","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/vitamin-e-acetate.html","C31H52O3","free base","Tocopherol acetate","CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=C(C)C(=C(C)C(=C2O1)C)OC(C)=O",10.45,3,0,14]
["S3684","Methacholine chloride","h8","L1300-12","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","019193","Immunology/Inflammation","AChR","Neuronal Signaling","Methacholine (Mecholyl, Acetyl-β-methylcholine) is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic nervous system but has little effects on the nicotinic receptors.",195.69,"62-51-1",39,199.29,39,199.29,"http://selleckchem.com/products/methacholine-chloride.html","C8H18NO2.Cl","chloride","Mecholyl chloride, Acetyl-β-methylcholine chloride","[Cl-].CC(C[N+](C)(C)C)OC(C)=O",-3.492,2,0,4]
["S3687","Urea","a9","L1300-12","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","Martindale the Extra Pharmacopoei, EP10.2, USP43-NF38, KP X, Ph.Int_6th, JP17, IP2010","017698","Others","Others","Metabolism","Urea (Carbonyldiamide, Ureophil) is a highly soluble organic compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.",60.06,"57-13-6",12,199.8,12,199.8,"http://selleckchem.com/products/urea.html","CH4N2O","free base","Carbonyldiamide, Ureophil","NC(N)=O",-1.043,1,2,0]
["S3689","Ethidium bromide","b9","L1300-12","in 10mM DMSO",null,"USP42-NF37",null,"Others","Others","Others","Ethidium Bromide (Homidium bromide, EtBr, EB) is an intercalating agent which resembles a DNA base pair and commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.",394.31,"1239-45-8",78,197.81,7,17.75,"http://selleckchem.com/products/ethidium-bromide.html","C21H20N3.Br","bromide","Homidium bromide, EtBr, EB","[Br-].CC[N+]1=C2C=C(N)C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N",1.79,0,2,2]
["S3690","Pargyline hydrochloride","c9","L1300-12","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia","013448","Cardiovascular Disease","MAO","Metabolism","Pargyline is an irreversible inhibitor of monoamine oxidase (MAO)-B with Ki values of 13 and 0.5 μM for time-dependent inhibition of the activity of MAO-A and -B, respectivey.",195.69,"306-07-0",39,199.29,39,199.29,"http://selleckchem.com/products/pargyline-hydrochloride.html","C11H13N.HCl","hydrochloride","Pargylamine hydrochloride","Cl.CN(CC#C)CC1=CC=CC=C1",3.477,0,0,3]
["S3692","N-Ethylmaleimide (NEM)","d9","L1300-12","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.2",null,"Neurological Disease","Cysteine Protease,DUB","Proteases","N-Ethylmaleimide (NEM) is an organic compound that is derived from maleic acid. It is an irreversible inhibitor of all cysteine peptidases, with alkylation occurring at the active site thiol group. N-Ethylmaleimide (NEM) inactivates endogenous deubiquitinating enzymes (DUBs). N-Ethylmaleimide (NEM) specifically inhibits phosphate transport in mitochondria.",125.13,"128-53-0",25,199.79,25,199.79,"http://selleckchem.com/products/n-ethylmaleimide-nem.html","C6H7NO2","free base","N/A","CCN1C(=O)C=CC1=O",0.16,2,0,1]
["S3693","2,6-Dihydroxypurine","e9","L1300-12","in 10mM DMSO",null,"USP43-NF38",null,"Immunology/Respiratory Disease","Others","Others","2,6-Dihydroxypurine (Xanthine, Isoxanthine) is a purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is a product on the pathway of purine degradation.",152.11,"69-89-6",2,13.15,"<1",0,"http://selleckchem.com/products/2-6-dihydroxypurine.html","C5H4N4O2","free base","Xanthine, Isoxanthine","O=C1NC(=O)C2=C(N1)N=C[NH]2",-0.718,3,3,0]
["S3694","Glucosamine hydrochloride","f9","L1300-12","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.5,BP2017",null,"Inflammation","Others","Immunology & Inflammation","Glucosamine (2-Amino-2-deoxy-glucose, Chitosamine) is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, also presents in the shells of shellfish, animal bones, bone marrow, and fungi. Glucosamine is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.",215.63,"66-84-2",4,18.55,43,199.42,"http://selleckchem.com/products/glucosamine-hydrochloride.html","C6H13NO5.HCl","hydrochloride","2-Amino-2-deoxy-glucose HCl, Chitosamine HCl","Cl.NC1C(O)OC(CO)C(O)C1O",-2.422,1,4,1]
["S3697","Mafenide hydrochloride","g9","L1300-12","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","201511,206716","Infection","Carbonic Anhydrase","Metabolism","Mafenide is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.",222.69,"138-37-4",44,197.58,44,197.58,"http://selleckchem.com/products/mafenide-hydrochloride.html","C7H10N2O2S.HCl","hydrochloride","4-Aminomethylbenzenesulfonamide hydrochloride","Cl.NCC1=CC=C(C=C1)[S](N)(=O)=O",0.023,2,2,2]
["S3698","Nortriptyline hydrochloride","h9","L1300-12","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.3,KP Ⅹ,JP17,BP2017,IP2010","073556,073667,074054,074132,074234,074835,075520,075606,077965","Neurological Disease/Psychotic disorders","Autophagy","Autophagy","Nortriptyline hydrochloride (Desitriptyline, ELF-101, EN-7048, Desmethylamitriptyline) is the hydrochloride salt form of nortriptyline, a tricyclic antidepressant agent used for short-term treatment of various forms of depression.",299.84,"894-71-3",59,196.77,59,196.77,"http://selleckchem.com/products/nortriptyline-hydrochloride.html","C19H21N.HCl","hydrochloride","Desitriptyline HCl, ELF-101 hydrochloride, EN-7048 hydrochloride, Desmethylamitriptyline hydrochloride","Cl.CNCCC=C1C2=C(CCC3=C1C=CC=C3)C=CC=C2",4.618,0,1,3]
["S3701","Benactyzine hydrochloride","a10","L1300-12","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Psychotic disorders","AChR","Neuronal Signaling","Benactyzine hydrochloride is a centrally acting muscarinic antagonist. It is used as an antidepressant in the treatment of depression and associated anxiety.",363.88,"57-37-4",72,197.87,72,197.87,"http://selleckchem.com/products/benactyzine-hydrochloride.html","C20H25NO3.HCl","hydrochloride","N/A","Cl.CCN(CC)CCOC(=O)C(O)(C1=CC=CC=C1)C2=CC=CC=C2",3.832,2,0,9]
["S3703","Phenethyl alcohol","b10","L1300-12","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Infection","Bacterial","Microbiology","Phenethyl alcohol (2-phenylethanol, 2-Phenylethyl alcohol, Benzeneethanol, Phenylethanol) is an antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence and preservative in pharmaceutics and perfumery.",122.16,"60-12-8","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/phenethyl-alcohol.html","C8H10O","free base","2-phenylethanol, 2-Phenylethyl alcohol, Benzeneethanol, Phenylethanol","OCCC1=CC=CC=C1",1.546,0,1,2]
["S3704","4-Methylbenzylidene camphor","c10","L1300-12","in 10mM DMSO","NDC",null,null,"Others","Others","Others","4-Methylbenzylidene camphor (Enzacamene, 4-MBC) is an organic camphor derivative that is used in the cosmetic industry for its ability to protect the skin against UV, specifically UV B radiation.",254.37,"36861-47-9",50,196.56,"<1",0,"http://selleckchem.com/products/4-methylbenzylidene-camphor.html","C18H22O","free base","Enzacamene, 4-MBC","CC1=CC=C(C=C1)\\C=C/2C3CCC(C)(C2=O)C3(C)C",4.473,1,0,1]
["S3705","Chlorobutanol","d10","L1300-12","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010",null,"Neurological Disease","Fungal","Microbiology","Chlorobutanol (Chlorbutol, Chloreton, Chloretone, Chlortran|, trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic with antibacterial and antifungal properties.",177.46,"57-15-8",35,197.23,"<1",0,"http://selleckchem.com/products/chlorobutanol.html","C4H7Cl3O","free base","Chlorbutol, Chloreton, Chloretone, Chlortran","CC(C)(O)C(Cl)(Cl)Cl",1.822,0,0,1]
["S3706","Sarpogrelate hydrochloride","e10","L1300-12","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Cardiovascular Disease/Endocrinology/Metabolic Disease","5-HT Receptor","Neuronal Signaling","Sarpogrelate (MCI-9042) is a selective 5-HT2A antagonist with pKi values of 8.52, 7.43 and 6.57 for 5-HT2A, 5-HT2C and 5-HT2B receptors respectively.",465.97,"135159-51-2",93,199.58,93,199.58,"http://selleckchem.com/products/sarpogrelate-hydrochloride.html","C24H31NO6.HCl","hydrochloride","MCI-9042","Cl.COC1=CC=CC(=C1)CCC2=C(OCC(CN(C)C)OC(=O)CCC(O)=O)C=CC=C2",1.427,5,0,14]
["S3707","Ethopabate","f10","L1300-12","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017,IP2010",null,"Infection/Parasitology","Parasite","Microbiology","Ethopabate (ETP, Ethyl pabate) is a coccidiostat that is frequently used to prevent and treat coccidiosis in chickens.",237.25,"59-06-3",47,198.1,"<1",0,"http://selleckchem.com/products/ethopabate.html","C12H15NO4","free base","Ethyl pabate","CCOC1=CC(=CC=C1C(=O)OC)NC(C)=O",1.138,4,1,5]
["S3708","Sulfachloropyridazine","g10","L1300-12","in 10mM DMSO","DMF",null,null,"Infection","Antibiotics,Bacterial","Microbiology","Sulfachloropyridazine is an antibiotic used to treat a variety of bacterial infections.",284.72,"80-32-0",56,196.68,"<1",0,"http://selleckchem.com/products/sulfachloropyridazine.html","C10H9ClN4O2S","free base","N/A","NC1=CC=C(C=C1)[S](=O)(=O)NC2=CC=C(Cl)N=N2",1.365,4,2,3]
["S3709","Furagin","h10","L1300-12","in 10mM DMSO","Marketed in other country",null,null,"Cancer; Infection","Bacterial","Microbiology","Furagin (NF-416, F-35, Akritoin, Furazidin, Furazidine) is 2-substituted 5-nitrofuran, chemically and structurally similar to well-known antibacterial compound nitrofurantoin with antimicrobial activities.",264.19,"1672-88-4",52,196.83,"<1",0,"http://selleckchem.com/products/furagin.html","C10H8N4O5","free base","NF-416, F-35, Akritoin, Furazidin, Furazidine","[O-][N+](=O)C1=CC=C(O1)/C=C/C=N/N2CC(=O)NC2=O",0.465,4,1,4]
["S3711","Carbasalate Calcium","a11","L1300-12","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017",null,"Neurological Disease/Inflammation","Anti-infection","Microbiology","Carbasalate calcium (Iromin, Alcacyl, Omegin, Rheomin, Solupsan) is an analgesic, antipyretic, and anti-inflammatory drug as well as a platelet aggregation inhibitor.",458.43,"5749-67-7",11,23.99,91,198.5,"http://selleckchem.com/products/carbasalate-calcium.html","C18H14O8.CH4N2O.Ca","calcium salt","Iromin, Alcacyl, Omegin, Rheomin, Solupsan","CC(=O)OC1=C(C=CC=C1)C(=O)O[Ca]OC(=O)C2=C(OC(C)=O)C=CC=C2.NC(N)=O",1.594,9,2,10]
["S3713","Moxidectin","b11","L1300-12","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017","210867","Infection/Parasitology","Parasite","Microbiology","Moxidectin (Milbemycin B) is a potent, broad-spectrum endectocide with activity against a wide range of nematodes, insects and acari.",639.82,"113507-06-5",100,156.29,"<1",0,"http://selleckchem.com/products/moxidectin.html","C37H53NO8","free base","Milbemycin B","CO\\N=C1/CC2(CC3CC(C\\C=C(C)\\CC(C)/C=C/C=C/4COC5C(O)C(=CC(C(=O)O3)C45O)C)O2)OC(C1C)\\C(C)=C\\C(C)C",5.026,7,1,3]
["S3714","Lifitegrast","c11","L1300-12","in 10mM DMSO","FDA,DMF,NDC",null,"208073","Inflammation/Ophthalmology","Integrin","Cytoskeletal Signaling","Lifitegrast (SAR1118,SHP-606) is a novel small molecule integrin antagonist that inhibits a specific T cell-mediated inflammatory pathway involved in the pathogenesis of DED.",615.48,"1025967-78-5",100,162.47,"<1",0,"http://selleckchem.com/products/lifitegrast.html","C29H24Cl2N2O7S","free base","SAR1118,SHP-606","C[S](=O)(=O)C1=CC=CC(=C1)CC(NC(=O)C2=C(Cl)C=C3CN(CCC3=C2Cl)C(=O)C4=CC=C5C=COC5=C4)C(O)=O",4.79,6,1,7]
["S3716","Flibanserin","d11","L1300-12","in 10mM DMSO","FDA,NDC",null,"022526","Endocrinology","5-HT Receptor","Neuronal Signaling","Flibanserin (BIMT-17, BIMT-17-BS) is a nonhormonal, centrally acting molecule that acts as an agonist at postsynaptic 5-HT1A receptors and as an antagonist at 5-HT2A receptors.",390.4,"167933-07-5",78,199.8,"<1",0,"http://selleckchem.com/products/flibanserin.html","C20H21F3N4O","free base","BIMT-17, BIMT-17-BS","FC(F)(F)C1=CC=CC(=C1)N2CCN(CC2)CCN3C(=O)NC4=C3C=CC=C4",3.609,1,1,5]
["S3719","Topiroxostat","e11","L1300-12","in 10mM DMSO","PMDA",null,null,"Inflammation/Metabolic Disease","P450 (e.g. CYP17),Xanthine Oxidase","Metabolism","Topiroxostat is a xanthine oxidoreductase (XOR) inhibitor and used for treatment of gout and hyperuricemia. Topiroxostat exhibits weak CYP3A4-inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment.",248.24,"577778-58-6",40,161.13,"<1",0,"http://selleckchem.com/products/topiroxostat.html","C13H8N6","free base","N/A","N#CC1=NC=CC(=C1)C2=N[NH]C(=N2)C3=CC=NC=C3",1.141,4,1,2]
["S3720","Elafibranor","f11","L1300-12","in 10mM DMSO","EMA，FDA",null,"006231，218860","Metabolic Disease","PPAR","Metabolism","Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α(PPAR-alpha) and peroxisome proliferator-activated receptor-δ(PPAR-δ). It improves insulin sensitivity, glucose homeostasis, and lipid metabolism and reduces inflammation.",384.49,"923978-27-2",76,197.66,"<1",0,"http://selleckchem.com/products/elafibranor.html","C22H24O4S","free base","GFT505","CSC1=CC=C(C=C1)C(=O)\\C=C\\C2=CC(=C(OC(C)(C)C(O)=O)C(=C2)C)C",5.477,3,0,7]
["S3722","Isavuconazole","g11","L1300-12","in 10mM DMSO","EMA",null,null,"Infection","Fungal","Microbiology","Isavuconazole (BAL-4815, RO-0094815) is a new extended-spectrum triazole with activity against yeasts, molds, and dimorphic fungi that inhibits cytochrome P450 (CYP)-dependent 14α-lanosterol demethylation, which is essential for fungal cell membrane ergosterol synthesis.",437.47,"241479-67-4",87,198.87,"<1",0,"http://selleckchem.com/products/isavuconazole.html","C22H17F2N5OS","free base","BAL-4815, RO-0094815","CC(C1=NC(=CS1)C2=CC=C(C=C2)C#N)C(O)(C[N]3C=NC=N3)C4=CC(=CC=C4F)F",3.904,3,0,6]
["S3723","Ramosetron Hydrochloride","h11","L1300-12","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","5-HT Receptor","Neuronal Signaling","Ramosetron Hydrochloride (YM-060) is the hydrochloride salt of ramosetron, a selective serotonin (5-HT) receptor antagonist with potential antiemetic activity.",315.8,"132907-72-3",63,199.49,63,199.49,"http://selleckchem.com/products/ramosetron-hydrochloride.html","C17H17N3O.HCl","hydrochloride","YM-060","Cl.C[N]1C=C(C(=O)C2CCC3=C(C2)[NH]C=N3)C4=C1C=CC=C4",2.948,2,1,2]
["S3724","Velpatasvir","a2","L1300-13","in 10mM DMSO","FDA,EMA,NDC",null,"208341,209195","Infection","COVID-19,HCV Protease","Proteases","Velpatasvir (GS-5816,VEL) is a second-generation NS5A inhibitor that inhibits hepatitis C viral replication through acting on the crucial \"membranous web\" that facilitates RNA replication.",883,"1377049-84-7",100,113.25,100,113.25,"http://selleckchem.com/products/velpatasvir.html","C49H54N8O8","free base","GS-5816,VEL","COCC1CC(N(C1)C(=O)C(NC(=O)OC)C2=CC=CC=C2)C3=NC=C([NH]3)C4=CC=C5C(=C4)COC6=C5C=C7C=CC8=C(N=C([NH]8)C9CCC(C)N9C(=O)C(NC(=O)OC)C(C)C)C7=C6",5.789,10,4,13]
["S3726","Selexipag","b2","L1300-13","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"207947","Cardiovascular Disease","Prostaglandin Receptor","Immunology & Inflammation","Selexipag (NS-304, ACT-293987) is an orally active, first-in-class, selective prostacyclin IP receptor agonist with Ki value of 260 nM for human IP, whereas Ki values > 10,000 nM are measured at the other human G-protein-coupled prostanoid receptors (EP1-4, DP, FP and TP).",496.62,"475086-01-2",99,199.35,"<1",0,"http://selleckchem.com/products/selexipag.html","C26H32N4O4S","free base","NS-304, ACT-293987","CC(C)N(CCCCOCC(=O)N[S](C)(=O)=O)C1=NC(=C(N=C1)C2=CC=CC=C2)C3=CC=CC=C3",3.996,6,1,12]
["S3727","Vilanterol Trifenate","c2","L1300-13","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"203975,204275,209482","Immunology","Adrenergic Receptor","Neuronal Signaling","Vilanterol trifenatate (GW642444M) is a novel inhaled long-acting beta2 adrenoceptor agonist with inherent 24-hour activity for once daily treatment of COPD and asthma.",774.77,"503070-58-4",100,129.07,"<1",0,"http://selleckchem.com/products/vilanterol-trifenate.html","C24H33Cl2NO5.C20H16O2","trifenatate","GW642444M Trifenate","OCC1=CC(=CC=C1O)C(O)CNCCCCCCOCCOCC2=C(Cl)C=CC=C2Cl.OC(=O)C(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5",5.949,3,4,20]
["S3728","Grazoprevir","d2","L1300-13","in 10mM DMSO","FDA,EMA,NDC,PMDA",null,"208261","Infection","HCV Protease","Proteases","Grazoprevir anhydrous (MK5172) is a Hepatitis C Virus NS3/4A Protease inhibitor with IC50 values of 7pM, 4pM, and 62pM for HCV genotype 1a, 1B, and 4 respectively.",766.9,"1350514-68-9",100,130.4,"<1",0,"http://selleckchem.com/products/grazoprevir.html","C38H50N6O9S","free base","MK5172","COC1=CC2=NC3=C(CCCCCC4CC4OC(=O)NC(C(=O)N5CC(CC5C(=O)NC6(CC6C=C)C(=O)N[S](=O)(=O)C7CC7)O3)C(C)(C)C)N=C2C=C1",3.975,11,3,8]
["S3729","Iron sucrose","e2","L1300-13","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia","021135","Hematology","Others","Others","Iron sucrose (Iron saccharate, Sucroferric oxyhydroxide) is an intravenously administered iron product indicated in the treatment of iron deficiency anemia.",736.06,"8047-67-4",100,135.86,100,135.86,"http://selleckchem.com/products/iron-sucrose.html","C18H24Fe2O24","Iron saccharate","Iron saccharate, Sucroferric oxyhydroxide","[Fe+3].[Fe+3].OC(C(O)C(O)C([O-])=O)C(O)C([O-])=O.OC(C(O)C(O)C([O-])=O)C(O)C([O-])=O.OC(C(O)C(O)C([O-])=O)C(O)C([O-])=O",-16.899,0,12,15]
["S3730","Metaxalone","f2","L1300-13","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","022503,040445,040486,203399,203695,204770,207466,208774","Neurological Disease","Others","Others","Metaxalone (Skelaxin, Methaxalonum, Zorane) is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions.",221.25,"1665-48-1",44,198.87,"<1",0,"http://selleckchem.com/products/metaxalone.html","C12H15NO3","free base","Skelaxin, Methaxalonum, Zorane","CC1=CC(=CC(=C1)C)OCC2CNC(=O)O2",2.468,3,1,3]
["S3731","Tipiracil hydrochloride","g2","L1300-13","in 10mM DMSO","FDA,DMF",null,"207981","Cancer","Phosphorylase,Thymidylate Synthase","Metabolism","Tipiracil (MA-1) is an inhibitor of thymidine phosphorylase, the enzyme that degrades trifluridine into trifluorothymidine. Its combination with trifluridine increases the bioavailability of trifluridine.",279.12,"183204-72-0",8,28.66,55,197.05,"http://selleckchem.com/products/tipiracil-hydrochloride.html","C9H11ClN4O2.HCl","hydrochloride","MA-1 hydrochloride","Cl.ClC1=C(CN2CCCC2=N)NC(=O)NC1=O",-0.388,2,2,2]
["S3732","Avibactam sodium","h2","L1300-13","in 10mM DMSO","FDA",null,"206494","Infection","β-lactamase","Microbiology","Avibactam (AVE-1330A, NXL104) is a covalent, reversible, non-β-lactam β-lactamase inhibitor with IC50 values of 8, 80, and 38 nM for TEM-1, P99, and KPC-2 β-lactamases, respectively.",287.23,"1192491-61-4",57,198.45,57,198.45,"http://selleckchem.com/products/avibactam-sodium.html","C7H10N3O6.Na","sodium salt","AVE-1330A, NXL104","[Na+].NC(=O)C1CCC2CN1C(=O)N2O[S]([O-])(=O)=O",-3.785,3,1,3]
["S3733","Boceprevir","a3","L1300-13","in 10mM DMSO","FDA,EMA",null,"202258","Infection","COVID-19,HCV Protease","Proteases","Boceprevir (EBP 520, SCH 503034) is an oral, direct acting hepatitis C virus (HCV) protease inhibitor with Ki value of 14 nM for NS3. It is used in combination with other antiviral agents in the treatment of chronic hepatitis C, genotype 1.",519.68,"394730-60-0",100,192.43,"<1",0,"http://selleckchem.com/products/boceprevir.html","C27H45N5O5","free base","EBP 520, SCH 503034","CC(C)(C)NC(=O)NC(C(=O)N1CC2C(C1C(=O)NC(CC3CCC3)C(=O)C(N)=O)C2(C)C)C(C)(C)C",1.623,5,4,10]
["S3735","Umeclidinium bromide","b3","L1300-13","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"205382","Inflammation/Respiratory Disease","AChR","Neuronal Signaling","Umeclidinium bromide(GSK573719A) is a long-acting muscarinic antagonist approved for the maintenance treatment of chronic obstructive pulmonary disease (COPD).",508.49,"869113-09-7",100,196.66,"<1",0,"http://selleckchem.com/products/umeclidinium-bromide.html","C29H34NO2.Br","bromide","GSK573719A","[Br-].OC(C1=CC=CC=C1)(C2=CC=CC=C2)C34CC[N+](CCOCC5=CC=CC=C5)(CC3)CC4",0.924,1,0,8]
["S3738","Travoprost","c3","L1300-13","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,IP2010","091340,091341,203431,205050","Ophthalmology","Prostaglandin Receptor","GPCR & G Protein","Travoprost (Travoprostum) is a PGF2a analog that was launched as an ophthalmic solution administered topically for the treatment of elevated intraocular hypertension as a result of open-angle glaucoma, a common optic neuropathy, and a leading cause of blindness. It can act as an agonist of prostaglandin F receptor.",500.55,"157283-68-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/travoprost.html","C26H35F3O6","free base","Travoprostum","CC(C)OC(=O)CCC\\C=C/CC1C(O)CC(O)C1\\C=C\\C(O)COC2=CC(=CC=C2)C(F)(F)F",4.269,3,3,14]
["S3739","Calcipotriene","d3","L1300-13","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","077029,077579,078305,078468,090633,200935,205772,207163","Immunology","Vitamin","Metabolism","Calcipotriene (Calcipotriol, MC903) is a synthetic derivative of calcitriol, a form of vitamin D. It can induce differentiation and suppresses proliferation of keratinocytes, reversing abnormal keratinocyte changes in psoriasis, and lead to normalization of epidermal growth.  Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.",412.6,"112965-21-6",82,198.74,"<1",0,"http://selleckchem.com/products/calcipotriene.html","C27H40O3","free base","Calcipotriol, MC903","CC(\\C=C\\C(O)C1CC1)C2CCC3/C(CCCC23C)=C/C=C\\4CC(O)CC(O)C4=C",4.679,0,3,5]
["S3741","Benznidazole","e3","L1300-13","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,Ph.Int_6th","209570","Infection/Parasitology","Parasite","Microbiology","Benznidazole (Radanil) is a nitroimidazole derivative having an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis.",260.25,"22994-85-0",52,199.81,"<1",0,"http://selleckchem.com/products/benznidazole.html","C12H12N4O3","free base","Radanil","[O-][N+](=O)C1=NC=C[N]1CC(=O)NCC2=CC=CC=C2",1.002,2,1,5]
["S3742","Cholic acid","f3","L1300-13","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"205750","Metabolic Disease","Others","Metabolism","Cholic acid is a naturally occurring bile acid that is insoluble in water and is used to treat patients with genetic deficiencies in the synthesis of bile acids.",408.57,"81-25-4",81,198.25,"<1",0,"http://selleckchem.com/products/cholic-acid.html","C24H40O5","free base","N/A","CC(CCC(O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CC(O)C12C",2.912,1,3,4]
["S3745","Balsalazide disodium","g3","L1300-13","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP39-NF34","077806,077807,077883,206336,206529,206909","Inflammation/Gastrointestinal Disease","Immunology & Inflammation related,Interleukins,STAT","Immunology & Inflammation","Balsalazide Disodium is the disodium salt form of balsalazide, an aminosalicylate and oral prodrug that is enzymatically cleaved in the colon to produce the anti-inflammatory agent mesalazine. Balsalazide Disodium suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway.",437.31,"150399-21-6",87,198.94,87,198.94,"http://selleckchem.com/products/balsalazide-disodium.html","C17H13N3O6.2H2O.2Na","disodium salt dihydrate","N/A","O.O.[Na+].[Na+].OC1=CC=C(C=C1C([O-])=O)N=NC2=CC=C(C=C2)C(=O)NCCC([O-])=O",-0.838,3,2,7]
["S3746","Lumefantrine","h3","L1300-13","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,Ph.Int_6th","022268","Infection","Anti-infection","Microbiology","Lumefantrine (benflumetol) is an antimalarial agent used to treat acute uncomplicated malaria.",528.94,"82186-77-4",13,24.58,"<1",0,"http://selleckchem.com/products/lumefantrine.html","C30H32Cl3NO","free base","benflumetol","CCCCN(CCCC)CC(O)C1=CC(=CC\\2=C1C3=C(C=C(Cl)C=C3)C2=C/C4=CC=C(Cl)C=C4)Cl",9.196,0,1,10]
["S3747","Levothyroxine sodium","a4","L1300-13","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","076187,076752,076764,202231,205366,206163,208749,209713,210632,210831","Endocrinology","THR","Metabolism","Levothyroxine (L-T4, L-Thyroxine) is the major hormone derived from the thyroid gland. It is the agonist of Thyroid hormone receptor alpha and beta.",798.85,"55-03-8",100,125.18,"<1",0,"http://selleckchem.com/products/levothyroxine-sodium.html","C15H10I4NO4.Na","sodium salt","L-T4 sodium, L-Thyroxine sodium, LT4 sodium","[Na+].NC(CC1=CC(=C(OC2=CC(=C(O)C(=C2)I)I)C(=C1)I)I)C([O-])=O",3.031,1,2,5]
["S3750","Sodium benzoate","b4","L1300-13","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,JP17,BP2017,IP2010","205880,207096,208521","Infection/Inflammation/Respiratory Disease","Others","Others","Sodium benzoate (Benzoic acid sodium salt) is a preservative and uesd as a food additive which is bacteriostatic and fungistatic under acidic conditions.",144.1,"532-32-1",3,20.82,28,194.31,"http://selleckchem.com/products/sodium-benzoate.html","C7H5O2.Na","sodium salt","Benzoic acid sodium salt","[Na+].[O-]C(=O)C1=CC=CC=C1",-0.015,0,0,1]
["S3751","Quinidine hemisulfate hydrate","c4","L1300-13","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017","040045,081029,081030,081031,083288,083347,083393,083439,083583,083622,083640,083743,083808,083862,083879,083963,084003,084177,084549,084627,084631,084914,085038,085068,085103,085140,085175,085276,085322,085444,085583,085584,085632,086176,087011,087837,087909,088072,088973,089839","Infection/Parasitology","Sodium Channel","Transmembrane Transporters","Quinidine hemisulfate hydrate(Chinidin, Pitayine, β-quinine, (+)-quinidine) acts as a blocker of voltage-gated sodium channels, also an antimuscarinic and antimalarial.",391.47,"6591-63-5",100,154.12,9,13.87,"http://selleckchem.com/products/quinidine-sulfate.html","C20H24N2O2.1/2H2SO4.H2O","hemisulfate hydrate","Chinidin Sodium, Pitayine Sodium, β-quinine Sodium, (+)-quinidine Sodium","O.O.COC1=CC2=C(C=C1)N=CC=C2C(O)C3CC4CCN3CC4C=C.COC5=CC6=C(C=C5)N=CC=C6C(O)C7CC8CCN7CC8C=C.O[S](O)(=O)=O",4.446,4,2,8]
["S3754","4-Hydroxybenzoic acid","d4","L1300-13","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.2",null,"Others","Others","Others","4-Hydroxybenzoic acid (p-hydroxybenzoic acid, PHBA, para-Hydroxybenzoic acid, 4-hydroxybenzoate), also known as p-hydroxybenzoic acid (PHBA), is a phenolic derivative of benzoic acid and widely used in organic synthesis. It is the most widely distributed aromatic organic acid in the vegetable kingdom.",138.12,"99-96-7",27,195.48,0,0,"http://selleckchem.com/products/4-hydroxybenzoic-acid.html","C7H6O3","free base","p-hydroxybenzoic acid, PHBA, para-Hydroxybenzoic acid, 4-hydroxybenzoate","OC(=O)C1=CC=C(O)C=C1",1.217,1,1,1]
["S3756","Methyl salicylate","f4","L1300-13","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8,KP Ⅹ,JP17,BP2017,IP2010","022029","Metabolic Disease/Neurological Disease","TRP Channel","Transmembrane Transporters","Methyl salicylate (Betula oil, Gaultheria oil, Methyl 2-hydroxybenzoate, Natural wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. It is an agonist for TRPA1 and TRPV1.",152.15,"119-36-8","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/methyl-salicylate.html","C8H8O3","free base","2-Carbomethoxyphenol, Betula oil, Gaultheria oil, Methyl 2-hydroxybenzoate, Natural wintergreen oil","COC(=O)C1=C(O)C=CC=C1",1.443,2,1,2]
["S3758","Sinomenine hydrochloride","g4","L1300-13","in 10mM DMSO","CFDA","CP2005,EP9.2,BP2017",null,"Cardiovascular Disease/Neurological Disease/Immunology","Autophagy,Immunology & Inflammation related","Immunology & Inflammation","Sinomenine (SN, Cucoline, Kukoline, Sabianine A), extracted from the Chinese medicinal plant, sinomenium acutum, is a potent anti-inflammatory and neuroprotective agent.",365.85,"6080-33-7",73,199.54,0,0,"http://selleckchem.com/products/sinomenine-hydrochloride.html","C19H23NO4.HCl","hydrochloride","Cucoline hydrochloride, Kukoline hydrochloride, Sabianine A hydrochloride","Cl.COC1=C(O)C2=C(CC3C4C=C(OC)C(=O)CC24CCN3C)C=C1",2.056,3,1,2]
["S3759","Norcantharidin","h4","L1300-13","in 10mM DMSO","CFDA",null,null,"Angiology/Cancer","c-Met,EGFR","Protein Tyrosine Kinase","Norcantharidin (Endothall anhydride) is a synthetic anticancer compound which is a dual inhibitor for c-Met and EGFR in human colon cancers.",168.15,"29745-04-8",33,196.25,0,0,"http://selleckchem.com/products/norcantharidin.html","C8H8O4","free base","Endothall anhydride","O=C1OC(=O)C2C3CCC(O3)C12",-0.117,4,0,0]
["S3763","Cinnamaldehyde","a5","L1300-13","in 10mM DMSO",null,"BP2017;IP2010",null,"Cancer/Infection","TRP Channel","Transmembrane Transporters","Cinnamaldehyde is a flavonoid that is naturally synthesized by the shikimate pathway. Its supplementation can improve glucose and lipid homeostasis in diabetic animals; a TRPA1 agonist.",132.16,"14371-10-9","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/cinnamaldehyde.html","C9H8O","free base","N/A","O=C\\C=C\\C1=CC=CC=C1",1.949,1,0,2]
["S3766","Tanshinone IIA sulfonate sodium","b5","L1300-13","in 10mM DMSO","CFDA",null,null,"Cardiovascular Disease","Calcium Channel,P2 Receptor,P450 (e.g. CYP17)","Metabolism","Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivative of tanshinone IIA isolated as the main pharmacologically active natural compound from a traditional Chinese herbal medicine, the dried root of Salvia miltiorrhiza Bunge known as Danshen. Sodium tanshinone IIA sulfonate (STS) is a potent negative allosteric modulator of the human purinergic receptor P2X7. Sodium tanshinone IIA sulfonate (STS) inhibits the activity of CYP3A4 and store-operated Ca2+ entry (SOCE) through store-operated Ca2+ channels (SOCC) via downregulating the expression of transient receptor potential canonical proteins (TRPC).",396.39,"69659-80-9",79,199.3,0,0,"http://selleckchem.com/products/tanshinone-iia-sulfonate-sodium.html","C19H17O6S.Na","sodium salt","N/A","[Na+].CC1=C(OC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C)[S]([O-])(=O)=O",1.873,3,0,1]
["S3769","Palmatine","c5","L1300-13","in 10mM DMSO","CFDA","EP9.2,BP2017",null,"Infection/Inflammation/Ophthalmology","AChR","Neuronal Signaling","Palmatine (Berbericinine, Burasaine), an isoquinoline alkaloid, has sedative, antidepressant, antioxidative, anti-ulcerative, antacid, anticancer, and anti-metastatic activities.",352.4,"3486-67-7",70,198.64,0,0,"http://selleckchem.com/products/palmatine.html","C21H22NO4","free base","Berbericinine, Burasaine","COC1=CC2=C(C=C1OC)C3=CC4=C(C=[N+]3CC2)C(=C(OC)C=C4)OC",4.161,4,0,4]
["S3772","5-Hydroxymethylfurfural","d5","L1300-13","in 10mM DMSO",null,"USP42-NF37;BP2013",null,"Others","Others","Others","5-Hydroxymethylfurfural (5-HMF) is an important bio-sourced intermediate, formed from carbohydrates such as glucose or fructose and used for production of fuels and chemical intermediates.",126.11,"67-47-0",25,198.24,0,0,"http://selleckchem.com/products/5-hydroxymethylfurfural.html","C6H6O3","free base","N/A","OCC1=CC=C(O1)C=O",0.458,2,1,2]
["S3773","Tyrosol","e5","L1300-13","in 10mM DMSO","DMF","USP42-NF37",null,"Others","NF-κB","NF-κB","Tyrosol (4-Hydroxyphenylethanol, 4-Hydroxyphenethyl alcohol, 2-(4-Hydroxyphenyl)ethanol) is an antioxidant that is naturally present in several foods such as wines and green tea and is present most abundantly in olives.  Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects.",138.16,"501-94-0",27,195.43,0,0,"http://selleckchem.com/products/tyrosol.html","C8H10O2","free base","4-Hydroxyphenylethanol, 4-Hydroxyphenethyl alcohol, 2-(4-Hydroxyphenyl)ethanol","OCCC1=CC=C(O)C=C1",1.304,0,2,2]
["S3774","Dehydroandrographolide Succinate Potasium Salt","f5","L1300-13","in 10mM DMSO","CFDA",null,null,"Inflammation/Respiratory Disease","Immunology & Inflammation related","Immunology & Inflammation","Dehydroandrographolide Succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect.",570.67,"76958-99-1",10,17.52,0,0,"http://selleckchem.com/products/dehydroandrographolide-succinate-potasium-salt.html","C28H35O10.K","potassium salt","N/A","[K+].CC1(COC(=O)CCC([O-])=O)C(CCC2(C)C1CCC(=C)C2\\C=C\\C3=CCOC3=O)OC(=O)CCC(O)=O",1.553,7,0,13]
["S3775","Ligustrazine hydrochloride","g5","L1300-13","in 10mM DMSO","CFDA","CP2005",null,"Cardiovascular Disease/Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Ligustrazine hydrochloride (Tetramethylpyrazine, Tetrapyrazine) is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.",172.66,"76494-51-4",34,196.92,0,0,"http://selleckchem.com/products/ligustrazine-hydrochloride.html","C8H12N2.HCl","hydrochloride","Tetramethylpyrazine HCl, Tetrapyrazine HCl","Cl.CC1=NC(=C(C)N=C1C)C",1.041,2,0,0]
["S3776","Sophoricoside","h5","L1300-13","in 10mM DMSO","CFDA",null,null,"Cancer/Immunology/Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Sophoricoside (SOPH) is an isoflavone isolated from Sophora japonica (Leguminosae) with numerous pharmacological effects, including anti- inflammatory, anti-cancer and immunosuppressive effects.",432.38,"152-95-4",86,198.9,0,0,"http://selleckchem.com/products/sophoricoside.html","C21H20O10",0,"N/A","OCC1OC(OC2=CC=C(C=C2)C3=COC4=C(C(=CC(=C4)O)O)C3=O)C(O)C(O)C1O",0.21,4,6,4]
["S3779","cis-Anethole","a6","L1300-13","in 10mM DMSO",null,"BP2019",null,"Others","Others","Others","Anethole ((Z)-Anethole, Cis-p-Propenylanisole, Cis-p-Anethole) has two isomers, the cis(Z) isomer being 15-38 times more toxic to animal than the trans(E) isomer. cis-Anethole is found in anise and Only a low level is permitted in flavours.",148.2,"104-46-1","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/cis-anethole.html","C10H12O","free base","(Z)-Anethole, Cis-p-Propenylanisole, Cis-p-Anethole","COC1=CC=C(\\C=C\\C)C=C1",2.767,1,0,2]
["S3781","Ginkgolide C","b6","L1300-13","in 10mM DMSO",null,"CP2005;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","MMP","Proteases","Ginkgolide C (BN-52022), isolated from Ginkgo biloba leaves, is a flavone reported to have multiple biological functions, from decreased platelet aggregation to ameliorating Alzheimer disease. It is an activator of MMP-9.",440.4,"15291-76-6",88,199.82,0,0,"http://selleckchem.com/products/ginkgolide-c.html","C20H24O11","free base","BN-52022","CC1C(=O)OC2C(O)C34C5OC(=O)C3(OC6OC(=O)C(O)C46C(C5O)C(C)(C)C)C12O",-1.753,7,3,1]
["S3783","Echinacoside","c6","L1300-13","in 10mM DMSO",null,"BP2019;EP9.2",null,"Neurological Disease/Inflammation","Tyrosinase","Protein Tyrosine Kinase","Echinacoside, a natural polyphenolic compound, has various biological activities, such as antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative actions. Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche salsa, elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Echinacoside also has a remarkable antiosteoporotic activity.",786.73,"82854-37-3",100,127.11,0,0,"http://selleckchem.com/products/echinacoside.html","C35H46O20","free base","N/A","CC1OC(OC2C(O)C(OCCC3=CC(=C(O)C=C3)O)OC(COC4OC(CO)C(O)C(O)C4O)C2OC(=O)\\C=C\\C5=CC=C(O)C(=C5)O)C(O)C(O)C1O",-1.263,8,12,14]
["S3785","Notoginsenoside R1","d6","L1300-13","in 10mM DMSO",null,"CP2005",null,"Cancer/Cardiovascular Disease/Inflammation","Akt,ERK,PAI-1,PI3K","Metabolism","Notoginsenoside R1 (Sanchinoside R1) is the main ingredient with cardiovascular activity in Panax notoginseng. It inhibits TNF-α-induced PAI-1 overexpression via extracellular signal-related kinases (ERK1/2) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling pathways.",933.13,"80418-24-2",100,107.17,0,0,"http://selleckchem.com/products/notoginsenoside-r1.html","C47H80O18","free base","Sanchinoside R1, NG-R1, NGR1","CC(C)=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C2CCC3(C)C2C(O)CC4C5(C)CCC(O)C(C)(C)C5C(CC34C)OC6OC(CO)C(O)C(O)C6OC7OCC(O)C(O)C7O",-0.11,6,12,12]
["S3788","Carvacrol","e6","L1300-13","in 10mM DMSO",null,"BP2019;EP9.2",null,"Infection/Parasitology","AChR","Neuronal Signaling","Carvacrol (Cymophenol), monoterpenic phenol isomeric with thymol, has diverse activities such as antimicrobial, antitumor, an-timutagenic, antigenotoxic, analgesic, antispasmodic, anti-inflammatory, angiogenic, antiparasitic, antiplatelet, AChE inhibitory, antielastase, insecticidal, antihepatotoxic and hepatoprotective activities.",150.22,"499-75-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/carvacrol.html","C10H14O","free base","cymophenol","CC(C)C1=CC=C(C)C(=C1)O",3.268,0,1,1]
["S3791","Succinic acid","f6","L1300-13","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017",null,"Infection/Neurological Disease/Inflammation/Immunology","Others","Metabolism","Succinic acid (1,4-Butandioic Acid, 1,2-Ethanedicarboxylic acid, Amber acid, Asuccin, Butanedioic acid) is a crystalline organic acid which occurs in living tissue as an intermediate in glucose metabolism.",118.09,"110-15-6",23,194.77,0,0,"http://selleckchem.com/products/succinic-acid.html","C4H6O4","free base","1,4-Butandioic Acid, 1,2-Ethanedicarboxylic acid, Amber acid, Asuccin, Butanedioic acid","OC(=O)CCC(O)=O",-0.36,2,0,3]
["S3794","Palmitic acid","g6","L1300-13","in 10mM DMSO","DMF,NDC","USP42-NF37,EP9.1,BP2017,IP2010",null,"Immunology","Others","Others","Palmitic acid (Hexadecanoic acid, Cetylic acid) is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity.",256.42,"57-10-3",51,198.89,0,0,"http://selleckchem.com/products/palmitic-acid.html","C16H32O2","free base","hexadecanoic acid, Cetylic acid","CCCCCCCCCCCCCCCC(O)=O",6.393,1,0,14]
["S3797","Helicide","h6","L1300-13","in 10mM DMSO","Marketed in Canada",null,null,"Neurological Disease","Others","Others","Helicide (4-formylphenyl-O-β-d-allopyranoside), a main active constituent from seeds of the Chinese herb Helicia nilagirica, has been reported to exert a sedative, analgesic and hypnotic effect, and is used clinically to treat neurasthenic syndrome, vascular headaches and trigeminal neuralgia.",284.26,"80154-34-3",56,197,0,0,"http://selleckchem.com/products/helicide.html","C13H16O7","free base","4-formylphenyl-O-β-d-allopyranoside","OCC1OC(OC2=CC=C(C=O)C=C2)C(O)C(O)C1O",-0.583,3,4,4]
["S3799","Gentisic acid","a7","L1300-13","in 10mM DMSO","DMF","EP10.4, USP43-NF38",null,"Others","Immunology & Inflammation related","Immunology & Inflammation","Gentisic acid (2,5-dihydroxybenzoic acid, 5-Hydroxysalicylic acid, Hydroquinonecarboxylic acid, DHB), an active metabolite of salicylic acid degradation, has a broad spectrum of biological activity, such as anti-inflammatory, antirheumatic and antioxidant properties.",154.12,"490-79-9",30,194.65,0,0,"http://selleckchem.com/products/gentisic-acid.html","C7H6O4","free base","DHB, 2,5-dihydroxybenzoic acid, 5-Hydroxysalicylic acid, Gentianic acid, Carboxyhydroquinone, Hydroquinonecarboxylic acid","OC(=O)C1=C(O)C=CC(=C1)O",0.975,1,2,1]
["S3802","Trigonelline Hydrochloride","b7","L1300-13","in 10mM DMSO",null,"BP2019;EP9.2",null,"Nutritional support","Bacterial","Microbiology","Trigonelline (Nicotinic acid N-methylbetaine, Coffearine, Gynesine), a major alkaloid component of fenugreek, has hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities, and also has been shown to reduce diabetic auditory neuropathy and platelet aggregation.",173.6,"6138-41-6",18,103.69,0,0,"http://selleckchem.com/products/trigonelline-hydrochloride.html","C7H8NO2.Cl","chloride","Nicotinic acid N-methylbetaine Hydrochloride, Coffearine Hydrochloride, Gynesine Hydrochloride","[Cl-].C[N+]1=CC(=CC=C1)C(O)=O",-1.61,1,0,1]
["S3805","Stevioside","c7","L1300-13","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease/Endocrinology/Metabolic Disease","Others","Others","Stevioside is a natural sweetener extracted from leaves of Stevia rebaudiana (Bertoni) Bertoni.",804.87,"57817-89-7",100,124.24,0,0,"http://selleckchem.com/products/stevioside.html","C38H60O18","free base","N/A","CC12CCCC(C)(C1CCC34CC(=C)C(CCC23)(C4)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O",-1.729,7,11,10]
["S3807","Dehydroandrographolide","d7","L1300-13","in 10mM DMSO","CFDA",null,null,"Angiology/Infection/Inflammation","Chloride Channel","Transmembrane Transporters","Dehydroandrographolide, isolated from Andrographis paniculata (Burm. F.) Nees (Chuan-xin-lian), is a novel TMEM16A inhibitor and possesses multiple pharmacological activities, including anti-inflammation, anti-cancer, anti-bacterial, anti-virus and anti-hepatitis activity.",332.43,"134418-28-3",66,198.54,0,0,"http://selleckchem.com/products/dehydroandrographolide.html","C20H28O4","free base","N/A","CC1(CO)C(O)CCC2(C)C(C\\C=C3/C=COC3=O)C(=C)CCC12",2.502,2,2,3]
["S3809","Imperatorin","e7","L1300-13","in 10mM DMSO",null,"BP2019;EP9.2;CP2005",null,"Immunology/Infection","Calcium Channel","Transmembrane Transporters","Imperatorin (Ammidin, Marmelosin, Pentosalen, 8-Isoamylenoxypsoralen), a naturally occurring psoralen-type furanocoumarin, is a potent myorelaxant agent and acts as a calcium antagonist on vascular smooth muscle.",270.28,"482-44-0",54,199.79,0,0,"http://selleckchem.com/products/imperatorin.html","C16H14O4","free base","Ammidin, Marmelosin, Pentosalen, 8-Isoamylenoxypsoralen, 8-Isopentenyloxypsoralene","CC(C)=CCOC1=C2OC(=O)C=CC2=CC3=C1OC=C3",3.652,4,0,3]
["S3810","Scutellarin","f7","L1300-13","in 10mM DMSO",null,"CP2005",null,"Angiology/Cardiovascular Disease","Akt,NF-κB,STAT","JAK/STAT","Scutellarin (Breviscapine, Breviscapin, Scutellarein-7-glucuronide), the major active principal flavonoids extracted from the Chinese herbal medicines Scutellaria baicalensis and Erigeron breviscapus (Vant.) Hand-Mazz, has many pharmacological effects, such as antioxidant, antitumor, antiviral, and antiinflammatory activities. Scutellarin can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts.",462.36,"27740-01-8",50,108.14,0,0,"http://selleckchem.com/products/scutellarin.html","C21H18O12","free base","Breviscapine, Breviscapin, Scutellarein-7-glucuronide","OC1C(O)C(OC(C1O)C(O)=O)OC2=CC3=C(C(=O)C=C(O3)C4=CC=C(O)C=C4)C(=C2O)O",0.366,5,6,4]
["S3811","Ginsenoside Re","g7","L1300-13","in 10mM DMSO",null,"BP2019;EP9.2;CP2005",null,"Neurological Disease","Beta Amyloid,JNK,NF-κB","Neuronal Signaling","Ginsenoside Re (Ginsenoside B2, Panaxoside Re, Sanchinoside Re, Chikusetsusaponin Ivc), an extract from Panax notoginseng, is a major ginsenoside in ginseng and belongs to 20(S)-protopanaxatriol group. It has diverse in vitro and in vivo effects, including vasorelaxant, antioxidant, antihyperlipidemic, and angiogenic actions. Ginsenoside Re decreases the β-amyloid protein (Aβ). Ginsenoside Re plays a role in antiinflammation through inhibition of JNK and NF-κB.",947.15,"52286-59-6",100,105.58,0,0,"http://selleckchem.com/products/ginsenoside-re.html","C48H82O18","free base","Panaxoside Re, Sanchinoside Re, Chikusetsusaponin Ivc","CC1OC(OC2C(O)C(O)C(CO)OC2OC3CC4(C)C(CC(O)C5C(CCC45C)C(C)(CCC=C(C)C)OC6OC(CO)C(O)C(O)C6O)C7(C)CCC(O)C(C)(C)C37)C(O)C(O)C1O",0.267,6,12,12]
["S3812","Monocrotaline","h7","L1300-13","in 10mM DMSO",null,"BP2023",null,"Metabolic Disease; Cancer","Others","Others","Monocrotaline (MCT, Crotaline) is an 11-membered macrocyclic pyrrolizidine alkaloid (PA) that causes a pulmonary vascular syndrome in rats characterized by proliferative pulmonary vasculitis, pulmonary hypertension, and cor pulmonale.",325.36,"315-22-0",65,199.78,0,0,"http://selleckchem.com/products/monocrotaline.html","C16H23NO6","free base","Crotaline","CC1C(=O)OC2CCN3CC=C(COC(=O)C(C)(O)C1(C)O)C23",-0.015,4,0,0]
["S3817","Harmine hydrochloride","a8","L1300-13","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cancer/Neurological Disease/Psychotic disorders/Infection","5-HT Receptor,ADC Cytotoxin,DYRK,MAO","Cell Cycle","Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγ and cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.",248.71,"343-27-1",21,84.44,0,0,"http://selleckchem.com/products/harmine-hydrochloride.html","C13H12N2O.HCl","hydrochloride","Telepathine hydrochloride","Cl.COC1=CC2=C(C=C1)C3=CC=NC(=C3[NH]2)C",2.82,2,1,1]
["S3824","Quercitrin","b8","L1300-13","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Immunology & Inflammation related","Immunology & Inflammation","Quercitrin (3-rhamnosyl quercetin, Sophoretin, Meletin, Xanthaurine), a glycoside of quercetin, has been found as a main bioactive constituent in T. sinensis leaves and has antioxidant, anti-inflammatory, and anti-allergic activities.",448.38,"522-12-3",89,198.49,0,0,"http://selleckchem.com/products/quercitrin.html","C21H20O11","free base","3-rhamnosyl quercetin, Sophoretin, Meletin, Xanthaurine","CC1OC(OC2=C(OC3=C(C(=CC(=C3)O)O)C2=O)C4=CC(=C(O)C=C4)O)C(O)C(O)C1O",0.589,4,7,3]
["S3835","Loganin","c8","L1300-13","in 10mM DMSO",null,"BP2019;EP9.2;CP2005",null,"Neurological Disease","AChR,BACE,BChE","Neuronal Signaling","Loganin (Loganoside) is an iridoid glycoside first isolated from the seeds of Strychnos nux-vomica, a member of the Loganiaceae family. It is a non-competitive inhibitor of BACE1 with IC50 of 47.97 μM an also inhibits AChE and BChE with IC50 values of 3.95 μM and 33.02 μM, respectively.",390.38,"18524-94-2",78,199.81,0,0,"http://selleckchem.com/products/loganin.html","C17H26O10","free base","Loganoside","COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C3C(C)C(O)CC13",-1.895,5,5,5]
["S3842","Isoquercitrin","d8","L1300-13","in 10mM DMSO",null,"BP2019",null,"Cardiovascular Disease/Inflammation","Wnt/beta-catenin","Stem Cells & Wnt","Isoquercitrin (Hirsutrin, 3-Glucosylquercetin, Quercetin 3-o-glucopyranoside), a flavonoid compound with anticancer activity isolated from Bidens bipinnata L, is an inhibitor of Wnt/β-catenin that acts downstream of the β-catenin nuclear translocation.",464.38,"482-35-9",92,198.11,0,0,"http://selleckchem.com/products/isoquercitrin.html","C21H20O12","free base","Hirsutrin, 3-Glucosylquercetin, Quercetin 3-o-glucopyranoside","OCC1OC(OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(O)C=C4)O)C(O)C(O)C1O",-0.3,4,8,4]
["S3843","Madecassoside","e8","L1300-13","in 10mM DMSO","NDC",null,null,"Cardiovascular Disease/Psychotic disorders","Others","Others","Madecassoside (Asiaticoside A) is the main active triterpene constituent of Centella asiatica herbs, a traditional Chinese medicine for wound healing and scar management.",975.12,"34540-22-2",100,102.55,100,102.55,"http://selleckchem.com/products/madecassoside.html","C48H78O20","free base","Asiaticoside A","CC1CCC2(CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(CO)C5C(O)CC34C)C2C1C)C(=O)OC6OC(COC7OC(CO)C(OC8OC(C)C(O)C(O)C8O)C(O)C7O)C(O)C(O)C6O",-1.27,7,13,10]
["S3846","Eupatilin","f8","L1300-13","in 10mM DMSO","marketed in Korea",null,null,"Inflammation","PPAR","Metabolism","Eupatilin (NSC 122413), a major flavonoid from Artemisia plants, possesses various beneficial biological effects including anti-inflammation, anti-tumor, anti-cancer, anti-allergy, and anti-oxidation activity. Eupatilin, a lipophilic flavonoid isolated from Artemisia species, is a PPARα agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities.",344.32,"22368-21-4",68,197.49,0,0,"http://selleckchem.com/products/eupatilin.html","C18H16O7","free base","NSC 122413","COC1=CC=C(C=C1OC)C2=CC(=O)C3=C(O2)C=C(O)C(=C3O)OC",2.603,5,2,4]
["S3847","Panaxatriol","g8","L1300-13","in 10mM DMSO","CFDA",null,null,"Others","Others","Others","Panaxatriol is a triterpene sapogenin originally found in species of Panax (ginseng) and exhibits anti-inflammatory, hepatoprotective, anti-arrhythmic, and antioxidative activities.",476.73,"32791-84-7",95,199.27,0,0,"http://selleckchem.com/products/panaxatriol.html","C30H52O4","free base","N/A","CC1(C)CCCC(C)(O1)C2CCC3(C)C2C(O)CC4C5(C)CCC(O)C(C)(C)C5C(O)CC34C",4.285,1,3,1]
["S3849","D-Galactose","h8","L1300-13","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,BP2013,IP2010",null,"Neurological Disease","Others","Others","D-Galactose (D-Galactopyranose, D-(+)-Galactose) is an aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins and is converted enzymatically into D-glucose for metabolism or polysaccharides for storage. It accelerates senescence in invertebrates and mammals and has been used as a model for aging.",180.16,"59-23-4",36,199.82,0,0,"http://selleckchem.com/products/d-galactose.html","C6H12O6","free base","D-Galactopyranose, D-(+)-Galactose","OCC1OC(O)C(O)C(O)C1O",-2.514,1,4,1]
["S3850","Glucosamine sulfate","a9","L1300-13","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8,BP2017",null,"Immunology/Inflammation/Neurological Disease","Others","Others","Glucosamine sulfate (D-Glucosaminesulfate, D-Glucosamine sulphate) is a dietary supplement commonly used in the treatment of osteoarthritis. It is a type of glycosaminoglycan, which is a naturally occurring major component of joint cartilage and joint fluid.",277.25,"29031-19-4",4,14.43,55,198.38,"http://selleckchem.com/products/glucosamine-sulfate.html","C6H13NO5.H2SO4","sulfate","D-Glucosaminesulfate, D-Glucosamine sulphate","NC(C=O)C(O)C(O)C(O)CO.O[S](O)(=O)=O",-3.688,1,5,5]
["S3851","Camphor","b9","L1300-13","in 10mM DMSO","DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,IP2010",null,"Immunology/Inflammation","TRP Channel","Transmembrane Transporters","Camphor (2-Bornanone, Bornan-2-one, 2-Camphanone, Formosa) is a bicyclic monoterpene ketone found widely in plants, especially cinnamomum camphora and used topically as a skin antipruritic and as an anti-infective agent.",152.23,"76-22-2",30,197.07,0,0,"http://selleckchem.com/products/camphor.html","C10H16O","free base","2-Bornanone, Bornan-2-one, 2-Camphanone, Formosa","CC1(C)C2CCC1(C)C(=O)C2",2.075,1,0,0]
["S3854","Tetrahydropalmatine hydrochloride","c9","L1300-13","in 10mM DMSO","CFDA","BP2017",null,"Inflammation/Parasite","ADC Cytotoxin,Dopamine Receptor","Neuronal Signaling","Tetrahydropalmatine (THP, Gindarine, 1-Tetrahydropalmitine) is an isoquinoline alkaloid found in several different plant species, mainly in the Corydalis genus (Yan Hu Suo), but also in other plants such as Stephania rotunda. It is a potent  muscle relaxant. Tetrahydropalmatine hydrochloride acts through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats.",391.89,"6024-85-7",12,30.62,0,0,"http://selleckchem.com/products/tetrahydropalmatine-hydrochloride.html","C21H25NO4.HCl","hydrochloride","Gindarine hydrochloride, 1-Tetrahydropalmitine HCl","Cl.COC1=C(OC)C2=C(CC3N(CCC4=C3C=C(OC)C(=C4)OC)C2)C=C1",3.981,4,0,4]
["S3856","Allantoin","d9","L1300-13","in 10mM DMSO","DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,KP Ⅹ,EP9.1,BP2017,IP2010",null,"Others","Others","Others","Allantoin (Glyoxyldiureide, 5-Ureidohydantoin), produced from uric acid, is a major metabolic intermediate in most organisms including animals, plants and bacteria.",158.12,"97-59-6",7,44.27,0,0,"http://selleckchem.com/products/allantoin.html","C4H6N4O3","free base","Glyoxyldiureide, 5-Ureidohydantoin","NC(=O)NC1NC(=O)NC1=O",-1.76,3,4,1]
["S3858","Lawsone","e9","L1300-13","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Infection","Others","Others","Lawsone (Hennotannic acid, 2-hydroxy-1,4-naphthoquinone) is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well as in the flower of water hyacinth (Eichhornia crassipes).",174.15,"83-72-7",34,195.23,0,0,"http://selleckchem.com/products/lawsone.html","C10H6O3","free base","Hennotannic acid, 2-hydroxy-1,4-naphthoquinone","OC1=CC(=O)C2=C(C=CC=C2)C1=O",1.22,2,1,0]
["S3865","Taurochenodeoxycholic acid","f9","L1300-13","in 10mM DMSO","CFDA",null,null,"Inflammation/Immunology","Caspase,TNF-alpha","Apoptosis","Taurochenodeoxycholic acid (Taurochenodeoxycholate, TCDCA, Chenodeoxycholyltaurine), a bile acid formed in the liver of most species, is used as a cholagogue and choleretic.",499.7,"516-35-8",99,198.12,0,0,"http://selleckchem.com/products/taurochenodeoxycholic-acid.html","C26H45NO6S","free base","Taurochenodeoxycholate, TCDCA, 12-Deoxycholyltaurine, Chenodeoxycholyltaurine, Chenyltaurine","CC(CCC(=O)NCC[S](O)(=O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C",2.997,1,3,7]
["S3866","Galanthamine","g9","L1300-13","in 10mM DMSO","DMF,CFDA",null,null,"Neurological Disease","AChR","Neuronal Signaling","Galanthamine (Galantamine, Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is a phenanthrene alkaloid and a reversible, competitive acetylcholinesterase inhibitor with IC50 of 0.35 μM, exhibits 50-fold selectivity against butyryl-cholinesterase. It is studied as a treatment for Alzheimer's disease and other central nervous system disorders.",287.35,"357-70-0",100,348.01,57,198.36,"http://selleckchem.com/products/galanthamine.html","C17H21NO3","free base","Galantamine, Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine","COC1=C2OC3CC(O)C=CC34CCN(C)CC(=C24)C=C1",1.442,2,1,1]
["S3868","Harmine","h9","L1300-13","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cancer/Neurological Disease/Psychotic disorders/Infection","MAO,PPAR","Metabolism","Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγ and cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.",212.25,"442-51-3",42,197.88,0,0,"http://selleckchem.com/products/harmine.html","C13H12N2O","free base","Telepathine","COC1=CC2=C(C=C1)C3=CC=NC(=C3[NH]2)C",2.438,2,1,1]
["S3870","D-Pinitol","a10","L1300-13","in 10mM DMSO","CFDA",null,null,"Neurological Disease","Influenza Virus","Microbiology","D-pinitol (Methylinositol, Pinitol, 3-O-Methyl-D-chiro-inositol, D-(+)-Pinitol, Inzitol) is a naturally occurring compound derived from soy and has significant pharmacological activitites such as inhibition of the T-helpercell-1 response, antiviral, larvicidal, antiinflammatory, antihyperlipidemic, cardioprotective, inhibition of ovalbumin-induced airway inflammation and antioxidant.",194.18,"10284-63-6",38,195.69,0,0,"http://selleckchem.com/products/d-pinitol.html","C7H14O6","free base","Methylinositol, Pinitol, 3-O-Methyl-D-chiro-inositol, D-(+)-Pinitol, Inzitol","COC1C(O)C(O)C(O)C(O)C1O",-2.656,1,5,1]
["S3872","Guaiacol","b10","L1300-13","in 10mM DMSO","DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017",null,"Neurological Disease","COX,NF-κB","NF-κB","Guaiacol (O-methoxyphenol, 2-hydroxyanisole, O-methylcatechol) is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. It is a precursor to various flavorants, such as eugenoland vanillin. Guaiacol, a phenolic compound isolated from Guaiac resin, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Anti-inflammatory activity.",124.14,"90-05-1",24,193.33,0,0,"http://selleckchem.com/products/guaiacol.html","C7H8O2","free base","o-methoxyphenol, 2-hydroxyanisole, O-methylcatechol","COC1=C(O)C=CC=C1",1.571,1,1,1]
["S3876","Indigo","c10","L1300-13","in 10mM DMSO","DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,JP16,IP2010",null,"Others","Dyes","Others","Indigo (Indigotin) dye is an organic compound with a distinctive blue color. It is extracted from the leaves of certain plants or synthetic.",262.26,"482-89-3",33,125.83,0,0,"http://selleckchem.com/products/indigo.html","C16H10N2O2","free base","Indigotin","O=C1\\C(NC2=C1C=CC=C2)=C\\3NC4=C(C=CC=C4)C3=O",2.106,2,2,0]
["S3881","Scopoletin","d10","L1300-13","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Immunology & Inflammation related","Immunology & Inflammation","Scopoletin (Esculetin 6-methyl ether, Gelseminic acid, 6-Methylesculetin, Chrysatropic acid) is the main bioactive constituent of flower buds from Magnolia fargesii with anti-inflammatory, hypouricemic, and antioxidant activities.",192.17,"92-61-5",38,197.74,0,0,"http://selleckchem.com/products/scopoletin.html","C10H8O4","free base","Esculetin 6-methyl ether, Gelseminic acid, 6-Methylesculetin, Chrysatropic acid","COC1=CC2=C(OC(=O)C=C2)C=C1O",1.641,3,1,1]
["S3883","Protopine","e10","L1300-13","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cancer/Inflammation","ADC Cytotoxin,Calcium Channel","Transmembrane Transporters","Protopine (Corydinine, Fumarine, Biflorine, Macleyine), an alkaloid present in different plants, has been shown to exhibit a number of activities, such as inhibition of calcium influx through both voltage and receptor-operated channels and inhibition of rabbit blood platelet aggregation. It also possesses anti-cholinergic and anti-histaminic as well as anti-bacterial activities.",353.37,"130-86-9",30,84.9,0,0,"http://selleckchem.com/products/protopine.html","C20H19NO5","free base","Corydinine, Fumarine, Biflorine, Macleyine","CN1CCC2=C(C=C3OCOC3=C2)C(=O)CC4=C(C1)C5=C(OCO5)C=C4",2.953,5,0,0]
["S3885","Pyrogallol","f10","L1300-13","in 10mM DMSO",null,"IP2010;USP36-NF31;BP2017;Ph.Int_6th;EP7.0",null,"Immunology/Infection","ROS","Immunology & Inflammation","Pyrogallol (1,2,3-trihydroxybenzene), an organic compound belonging to the phenol family, used as a photographic film developer and in the preparation of other chemicals. It is known to be a superoxide anion generator and ROS inducer.",126.11,"87-66-1",25,198.24,0,0,"http://selleckchem.com/products/pyrogallol.html","C6H6O3","free base","1,2,3-trihydroxybenzene","OC1=C(O)C(=CC=C1)O",1.103,0,3,0]
["S3887","α-L-Rhamnose monohydrate","g10","L1300-13","in 10mM DMSO","DMF","BP2015",null,"Others","Others","Others","α-L-Rhamnose monohydrate (6-deoxy-L-mannose monohydrate, α-L-Rhamnopyranose monohydrate) is used as a starting material for the production of furanones. It is an important material involved in the reaction of flavors developed during the preparation of various foods like bread, grilled meats, etc.",182.17,"6155-35-7",36,197.62,0,0,"https://www.selleckchem.com/products/a-l-rhamnose-monohydrate.html","C6H12O5.H2O","hydrate","6-deoxy-L-mannose monohydrate, α-L-Rhamnopyranose monohydrate","O.CC1OC(O)C(O)C(O)C1O",-1.833,1,3,0]
["S3889","Arteether","h10","L1300-13","in 10mM DMSO",null,"IP2010",null,"Infection/Parasitology","Parasite","Microbiology","Arteether is a well-known antimalarial drug which acts by producing free radicals within the malarial parasite.",312.4,"75887-54-6",62,198.46,0,0,"http://selleckchem.com/products/arteether.html","C17H28O5","free base","N/A","CCOC1OC2OC3(C)CCC4C(C)CCC(C1C)C24OO3",2.378,5,0,2]
["S3892","Isopsoralen","a11","L1300-13","in 10mM DMSO",null,"CP2005",null,"Others","ADC Cytotoxin,Immunology & Inflammation related","Immunology & Inflammation","Isopsoralen (Angelicin), also known as angelicin, is a constituent of roots and leaves of angelica with anti-inflammatory activity and regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways. It also shows antiviral activity against gammaherpesviruses.",186.16,"523-50-2",14,75.2,0,0,"http://selleckchem.com/products/isopsoralen.html","C11H6O3","free base","angelicin","O=C1OC2=C(C=C1)C=CC3=C2C=CO3",2.203,3,0,0]
["S3893","Bornyl acetate","b11","L1300-13","in 10mM DMSO",null,"EP9.2;BP2017",null,"Others","Immunology & Inflammation related","Immunology & Inflammation","Bornyl acetate (Isobornyl, Bornyl acetic ether, 2-Camphanol), the main volatile constituent in numerous conifer oils and some Chinese traditional herbs, exhibits anti-inflammatory property and it is used as an analgesic.",196.29,"76-49-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/bornyl-acetate.html","C12H20O2","free base","Isobornyl acetate, Bornyl acetic ether, 2-Camphanol acetate","CC(=O)OC1CC2CCC1(C)C2(C)C",2.354,2,0,2]
["S3895","Sophoridine","c11","L1300-13","in 10mM DMSO","CFDA",null,null,"Cancer","Apoptosis related","Apoptosis","Sophoridine (5-Epidihydrosophocarpine, Dihydro-5-episophocarpine), a natural product obtained from medicinal plants, has a variety of pharmacological effects, including anti-cancer and anti-arrhythmia, and affects the immune and central nervous systems.",248.36,"6882-68-4",49,197.29,0,0,"http://selleckchem.com/products/sophoridine.html","C15H24N2O","free base","5-Epidihydrosophocarpine, Dihydro-5-episophocarpine","O=C1CCCC2C3CCCN4CCCC(CN12)C34",1.417,1,0,0]
["S3898","Hydroxy Camptothecine","d11","L1300-13","in 10mM DMSO","CFDA",null,null,"Cancer","Topoisomerase","DNA Damage/DNA Repair","Hydroxy Camptothecine (10-Hydroxycamptothecin, Hydroxycamptothecine) is a cell-permeable powerful DNA topoisomerase I inhibitor. It has selective inhibitory effect on the phosphorylation of histone H1 and H3, but less effect on other histones.",364.35,"64439-81-2",29,79.59,0,0,"http://selleckchem.com/products/hydroxy-camptothecine.html","C20H16N2O5","free base","10-Hydroxycamptothecin, Hydroxycamptothecine","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=CC5=C(C=CC(=C5)O)N=C34)C2=O",1.504,4,1,1]
["S3899","Hederagenin","e11","L1300-13","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","COX,NF-κB,NOS","Immunology & Inflammation","Hederagenin (Caulosapogenin, Hederagenol, Hederagenic acid, Astrantiagenin E) is a highly water insoluble triterpenoid compound that can be found in various plants including Hedera helix and Chenopodium quinoa. It exhibits a variety of biological activities, including potent antitumor properties both in vitro and in vivo. Hederagenin inhibits LPS-stimulated expression of iNOS, COX-2, and NF-κB.",472.7,"465-99-6",94,198.86,0,0,"http://selleckchem.com/products/hederagenin.html","C30H48O4","free base","Caulosapogenin, Hederagenol, Hederagenic acid, Astrantiagenin E","CC1(C)CCC2(CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(CO)C5CCC34C)C2C1)C(O)=O",5.356,1,2,2]
["S3901","Astragaloside IV","f11","L1300-13","in 10mM DMSO",null,"BP2019;EP9.2;CP2005",null,"Immunology/Infection","Akt,ERK,JNK,mTOR,NF-κB","MAPK","Astragaloside IV (AST-IV, AS-IV) is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine. It has various effect on the cardiovascular, immune, digestive, and nervous systems. AS-IV suppresses activation of p-Akt, p-mTOR, p-NF-κB and p-Erk1/2.",784.97,"84687-43-4",100,127.39,0,0,"http://selleckchem.com/products/sastragaloside-iv.html","C41H68O14","free base","AST-IV, AS-IV","CC(C)(O)C1CCC(C)(O1)C2C(O)CC3(C)C4CC(OC5OC(CO)C(O)C(O)C5O)C6C(C)(C)C(CCC67CC47CCC23C)OC8OCC(O)C(O)C8O",-0.348,5,8,7]
["S3907","Bulleyaconi cine A","g11","L1300-13","in 10mM DMSO","CFDA",null,null,"Inflammation","Sodium Channel","Transmembrane Transporters","Bulleyaconi cine A (Bulleyaconitine A, BLA) is an active ingredient of Aconitum bulleyanum plants and classified as an \"aconitine-like\" alkaloid. It is a potent use-dependent blocker for both Nav1.7 and Nav1.8 Na+ currents.",627.76,"107668-79-1",7,11.15,0,0,"http://selleckchem.com/products/bulleyaconi-cine-a.html","C35H49NO9","free base","Bulleyaconitine A","CCN1CC2(CCC(OC)C34C5CC6(O)C(CC(OC(C)=O)(C(C(OC)C23)C14)C5C6C(=O)C7=CC=C(OC)C=C7)OC)COC",0.816,8,0,11]
["S3909","Catalpol","h11","L1300-13","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cancer/Endocrinology/Neurological Disease","Others","Others","Catalpol (Catalpinoside, Digitalis purpurea L), an iridoid glucoside contained richly in the roots of the small flowering plant species Rehmannia glutinosa Libosch, has been shown to have antioxidation, anti-inflammation, anti-apoptosis and other neuroprotective properties and plays a role in neuroprotection against hypoxic/ischemic injury, AD and PD in both in vivo and in vitro models.",362.33,"2415-24-9",72,198.71,0,0,"http://selleckchem.com/products/catalpol.html","C15H22O10","free base","Catalpinoside, Digitalis purpurea L","OCC1OC(OC2OC=CC3C(O)C4OC4(CO)C23)C(O)C(O)C1O",-3.581,4,6,4]
["S3914","α-Hederin","a2","L1300-14","in 10mM DMSO",null,"BP2019",null,"Neurological Disease/Psychotic disorders","Others","Apoptosis","α-hederin is a water-soluble pentacyclic triterpenoid saponin which has shown hemolytic and apoptotic properties.",750.96,"27013-91-8",100,133.16,0,0,"http://selleckchem.com/products/alpha-hederin.html","C41H66O12","free base","N/A","CC1OC(OC2C(O)C(O)COC2OC3CCC4(C)C(CCC5(C)C4CC=C6C7CC(C)(C)CCC7(CCC56C)C(O)=O)C3(C)CO)C(O)C(O)C1O",3.261,5,6,6]
["S3919","Hederacoside C","b2","L1300-14","in 10mM DMSO",null,"BP2019;EP9.2",null,"Immunology/Inflammation","Others","Others","Hederacoside C (HDC, Kalopanaxsaponin B) is one of the active ingredients in Hedera helix leaf extract (Ivy Ex.) and used to treat respiratory disorders.",1221.38,"14216-03-6",70,57.31,0,0,"http://selleckchem.com/products/hederacoside-c.html","C59H96O26","free base","Kalopanaxsaponin B","CC1OC(OC2C(O)C(O)C(OCC3OC(OC(=O)C45CCC(C)(C)CC4C6=CCC7C8(C)CCC(OC9OCC(O)C(O)C9OC%10OC(C)C(O)C(O)C%10O)C(C)(CO)C8CCC7(C)C6(C)CC5)C(O)C(O)C3O)OC2CO)C(O)C(O)C1O",-1.274,11,15,14]
["S3921","Lathyrol","c2","L1300-14","in 10mM DMSO","NDC",null,null,"Cancer","Others","Others","Lathyrol is a natural product that is used for cancer treatment.",334.45,"34420-19-4",85,254.15,0,0,"http://selleckchem.com/products/lathyrol.html","C20H30O4","free base","N/A","CC1CC2(O)C(C1O)C(O)C(=C)CCC3C(\\C=C(C)\\C2=O)C3(C)C",2.421,1,2,0]
["S3923","Ginsenoside Rg1","d2","L1300-14","in 10mM DMSO","NDC","CP2005,EP9.2,BP2017",null,"Neurological Disease","Beta Amyloid,NF-κB","Neuronal Signaling","Ginsenoside Rg1 (Ginsenoside A2, Panaxoside A, Panaxoside Rg1, Sanchinoside C1, Sanchinoside Rg1), one of the major active components of ginseng, is identified as a protopanaxatriol-type and has pharmacological actions such as neuroprotective and anti-tumor effects on various cancer types. Ginsenoside Rg1 reduces cerebral Aβ levels and NF-κB nuclear translocation.",801.01,"22427-39-0",100,124.84,0,0,"http://selleckchem.com/products/ginsenoside-rg1.html","C42H72O14","free base","Ginsenoside A2, Panaxoside A, Panaxoside Rg1, Sanchinoside C1, Sanchinoside Rg1","CC(C)=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C2CCC3(C)C2C(O)CC4C5(C)CCC(O)C(C)(C)C5C(CC34C)OC6OC(CO)C(O)C(O)C6O",1.126,4,10,10]
["S3924","Ginsenoside Rb1","e2","L1300-14","in 10mM DMSO",null,"BP2019;EP9.2",null,"Neurological Disease","ATPase,IFN,IRAK,NF-κB,NOS,TLR,TNF-alpha","Transmembrane Transporters","Ginsenoside Rb1 (Gypenoside Ⅲ) is a protopanaxadiol that has diverse in vitro and in vivo effects, including neuroprotective, anti-inflammatory, and anti-obesity actions. Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65. Ginsenoside Rb1 reduces the expressions of TLR3, TLR4 and TRAF-6, and down-regulates the levels of TNF-α, IFN-β and iNOS.",1109.29,"41753-43-9",100,90.15,0,0,"http://selleckchem.com/products/ginsenoside-rb1.html","C54H92O23","free base","Gypenoside Ⅲ","CC(C)=CCCC(C)(OC1OC(COC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CCC45C",-1.198,8,15,16]
["S3925","(-)-Epicatechin gallate","f2","L1300-14","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cancer/Cardiovascular Disease","COX","Immunology & Inflammation","(-)-Epicatechin gallate (ECG) is an inhibitor of cyclooxygenase-1 (COX-1) with IC50 of 7.5 μM.",442.37,"1257-08-5",88,198.93,0,0,"http://selleckchem.com/products/epicatechin-gallate.html","C22H18O10","free base","(−)-ECG, (−)-Epicatechin 3-gallate, (−)-Epicatechin-3-O-gallate","OC1=CC2=C(CC(OC(=O)C3=CC(=C(O)C(=C3)O)O)C(O2)C4=CC=C(O)C(=C4)O)C(=C1)O",3.339,3,7,4]
["S3926","Forsythin","g2","L1300-14","in 10mM DMSO",null,"CP2005",null,"Infection","PDE","GPCR & G Protein","Forsythin (FOR, Phillyrin) is an active ingredient extracted from the fruit of the medicinal plant Forsythia suspensa (Thunb.) Vahl and has been shown to have antioxidant, antibacterial and antiinflammatory properties.",534.55,"487-41-2",100,187.07,0,0,"http://selleckchem.com/products/forsythin.html","C27H34O11","free base","Phillyrin","COC1=CC=C(C=C1OC)C2OCC3C2COC3C4=CC(=C(OC5OC(CO)C(O)C(O)C5O)C=C4)OC",0.479,7,4,8]
["S3927","Swertiamarin","h2","L1300-14","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cardiovascular Disease","Others","Others","Swertiamarin (Swertiamaroside) is a common secoiridoid found among the members of Gentianaceae with anti-inflammatory, anticancer, hypoglycemic and hypolipidemic activities.",374.34,"17388-39-5",74,197.68,0,0,"http://selleckchem.com/products/swertiamarin.html","C16H22O10","free base","Swertiamaroside","OCC1OC(OC2OC=C3C(=O)OCCC3(O)C2C=C)C(O)C(O)C1O",-2.381,5,4,4]
["S3930","Liquiritin","a3","L1300-14","in 10mM DMSO",null,"CP2005",null,"Infection","AKR1C","Immunology & Inflammation","Liquiritin (LIQ, Liquiritoside, Liquiritigenin-4'-O-glucoside) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities.",418.39,"551-15-5",100,239.01,0,0,"http://selleckchem.com/products/liquiritin.html","C21H22O9","free base","Liquiritoside, Liquiritigenin-4'-O-glucoside","OCC1OC(OC2=CC=C(C=C2)C3CC(=O)C4=C(O3)C=C(O)C=C4)C(O)C(O)C1O",0.686,4,5,4]
["S3935","Nonivamide","b3","L1300-14","in 10mM DMSO","NDC,HMA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017",null,"Others","TRP Channel","Transmembrane Transporters","Nonivamide (pelargonic acid vanillylamide, Pseudocapsaicin, Vanillyl-N-nonylamide), present in chili peppers, is commonly manufactured synthetically and used as a food additive to add pungency to seasonings, flavorings, and spice blends. Nonivamide is a agonist, which exhibits 4d-EC50 value of 5.1 mg/L in static toxicity tests.",293.4,"2444-46-4",58,197.68,"<1",0,"https://www.selleckchem.com/products/nonivamide.html","C17H27NO3","free base","pelargonic acid vanillylamide, Pseudocapsaicin, Vanillyl-N-nonylamide","CCCCCCCCC(=O)NCC1=CC(=C(O)C=C1)OC",4.103,2,2,10]
["S3944","Valproic acid (VPA)","c3","L1300-14","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,Ph.Int_6th,BP2017,IP2010","070195,070431,070631,070868,073178,073229,073484,074060,075379,075782,077105,077960,090517,091037","Neurological Disease/Infection/Psychotic disorders","Autophagy,HDAC,Mitophagy,Notch,PGC-1α","Epigenetics","Valproic acid (VPA, 2-Propylvaleric Acid, Valproate) is a fatty acid with anticonvulsant properties used in the treatment of epilepsy. It is also a histone deacetylase (HDAC) inhibitor and is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α. Valproic acid activates Notch-1 signaling.",144.21,"99-66-1","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/valproic-acid.html","C8H16O2","free base","2-Propylvaleric Acid, Valproate","CCCC(CCC)C(O)=O",2.749,1,0,5]
["S3945","L-Cycloserine","d3","L1300-14","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,Ph.Int_6th,JP17,IP2010","060593","Infection","Transferase","Metabolism","L-Cycloserine (Levcycloserine, Levcicloserina, Levcycloserinum, (-)-Cycloserine, (S)-Cycloserine) is a potent inhibitor of the sphingolipid pathway via inhibiting 3-ketodihydrosphingosine synthetase. It also inhibits HIV-1 cytopathic effects, replication, and infectivity.",102.09,"339-72-0",8,78.36,20,195.91,"http://selleckchem.com/products/l-cycloserine.html","C3H6N2O2","free base","Levcycloserine, Levcicloserina, Levcycloserinum, (-)-Cycloserine, (S)-Cycloserine","NC1CONC1=O",-1.788,2,2,0]
["S3950","Maltitol","e3","L1300-14","in 10mM DMSO",null,"USP38-NF33;BP2013;IP2010;Martindale:The Extra Pharmacopoeia",null,"Endocrinology/Metabolic Disease","Others","Others","Maltitol (Maltisorb, 4-O-α-glucopyranosyl-D-sorbitol) is a sugar alcohol (polyol) used as a sugar substitute. It is especially useful in the production of sweets, including sugarless hard candies, chewing gum, chocolates.",344.31,"585-88-6",20,58.09,0,0,"http://selleckchem.com/products/maltitol.html","C12H24O11","free base","Maltisorb, 4-O-α-glucopyranosyl-D-sorbitol","OCC(O)C(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)CO",-4.688,2,9,8]
["S3951","Tannic acid","f3","L1300-14","in 10mM DMSO","FDA,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,IP2010","011208","Immunology/Inflammation","CXCR","Immunology & Inflammation","Tannic acid (Gallotannic acid), a polyphenolic compound, is a CXCL12/CXCR4 inhibitor with antiangiogenic, anti-inflammatory and antitumor activity.",1701.2,"1401-55-4",100,58.78,0,0,"http://selleckchem.com/products/tannic-acid.html","C76H52O46","free base","Gallotannic acid","OC1=CC(=CC(=C1O)O)C(=O)OC2=C(O)C(=CC(=C2)C(=O)OCC3OC(OC(=O)C4=CC(=C(O)C(=C4)O)OC(=O)C5=CC(=C(O)C(=C5)O)O)C(OC(=O)C6=CC(=C(O)C(=C6)O)OC(=O)C7=CC(=C(O)C(=C7)O)O)C(OC(=O)C8=CC(=C(O)C(=C8)O)OC(=O)C9=CC(=C(O)C(=C9)O)O)C3OC(=O)C%10=CC(=C(O)C(=C%10)O)OC(=O)C%11=CC(=C(O)C(=C%11)O)O)O",8.813,21,25,31]
["S3956","Tetramethylpyrazine","g3","L1300-14","in 10mM DMSO","CFDA",null,null,"Others","Immunology & Inflammation related","Immunology & Inflammation","Tetramethylpyrazine (ligustrazine, TMP) is a natural compound isolated from Chinese herbal medicine Ligusticum wallichii (Chuan Xiong) with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.",136.19,"1124-11-4",27,198.25,0,0,"http://selleckchem.com/products/tetramethylpyrazine.html","C8H12N2","free base","ligustrazine","CC1=NC(=C(C)N=C1C)C",0.659,2,0,0]
["S3957","Gamma-Oryzanol","h3","L1300-14","in 10mM DMSO","CFDA,PMDA",null,null,"Neurological Disease","DNA Methyltransferase","Epigenetics","Gamma-oryzanol (GO), a nutriactive phytochemical naturally occurring in crude rice bran oil, is an antioxidant compound used to treat hyperlipidemia, disorders of menopause and to increase the muscle mass.  γ-Oryzanol is a potent DNA methyltransferases (DNMTs) inhibitor in the striatum of mice. γ-Oryzanol significantly inhibits the activities of DNMT1 (IC50=3.2 μM), DNMT3a (IC50=22.3 μM).",602.89,"11042-64-1",100,165.87,0,0,"http://selleckchem.com/products/gamma-oryzanol.html","C40H58O4","free base","N/A","COC1=CC(=CC=C1O)/C=C/C(=O)OC2CCC34CC35CCC6(C)C(CCC6(C)C5CCC4C2(C)C)C(C)CCC=C(C)C",9.806,3,1,9]
["S3959","(+)-Borneol","a4","L1300-14","in 10mM DMSO",null,"EP9.2;BP2017;Martindale:The Extra Pharmacopoeia",null,"Immunology/Inflammation","GABA Receptor","Neuronal Signaling","(+)-Borneol is one of enantiomers of borneol which is a valuable medical material, senior aromatic spice, and chemical material and has been used in food and also folk medicine.",154.25,"464-43-7",30,194.49,0,0,"http://selleckchem.com/products/positive-rotation-borneol.html","C10H18O","free base","N/A","CC1(C)C2CCC1(C)C(O)C2",1.975,0,1,0]
["S3965","Vanillyl Butyl Ether","b4","L1300-14","in 10mM DMSO","NDC",null,null,"Others","Others","Others","Vanillyl Butyl Ether (4-(Butoxymethyl)-2-methoxyphenol), an ether of monohydroxybenzoic acid, is added to food products as a flavoring agent. It is also present in cosmetics and personal care products as a fragrance ingredient, oral care agent, hair conditioning agent, and warming or cooling agent.",210.27,"82654-98-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/vanillyl-butyl-ether.html","C12H18O3",0,"4-(Butoxymethyl)-2-methoxyphenol","CCCCOCC1=CC(=C(O)C=C1)OC",2.704,2,1,6]
["S3966","Nifuratel","c4","L1300-14","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Infection/Inflammation","Fungal","Microbiology","Nifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action.",285.28,"4936-47-4",57,199.8,"<1",0,"https://www.selleckchem.com/products/nifuratel.html","C10H11N3O5S","free base","N/A","CSCC1CN(\\N=C\\C2=CC=C(O2)[N+]([O-])=O)C(=O)O1",1.743,4,0,5]
["S3967","Flavone","d4","L1300-14","in 10mM DMSO","DMF",null,null,"Others","Apoptosis related","Apoptosis","Flavone (2-Phenylchromone, 2-Phenyl-4-chromone, 2-Phenyl-4-benzopyron), a class of flavonoids, mainly found in spices and red or purple plant foods with antioxidant, anti-proliferative, anti-tumor, anti-microbial, estrogenic, acetyl cholinesterase, anti-inflammatory activities and are also used in cancer, cardiovascular disease, neurodegenerative disorders etc.",222.24,"525-82-6",44,197.98,0,0,"http://selleckchem.com/products/flavone.html","C15H10O2","free base","2-Phenylchromone, 2-Phenyl-4-chromone, 2-Phenyl-4-benzopyron","O=C1C=C(OC2=C1C=CC=C2)C3=CC=CC=C3",3.136,2,0,1]
["S3968","Histamine","e4","L1300-14","in 10mM DMSO","FDA,EMA,HMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","000734","Immunology","Histamine Receptor","Immunology & Inflammation","Histamine, an organic nitrogenous compound, is involved in local immune responses regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. It is a potent H1 and H2 receptor agonist.",111.15,"51-45-6",22,197.93,0,0,"http://selleckchem.com/products/histamine.html","C5H9N3","free base","N/A","NCCC1=C[NH]C=N1",-0.714,1,2,2]
["S3969","Veratric acid","f4","L1300-14","in 10mM DMSO",null,"BP2019;IP2010",null,"Cardiovascular Disease/Inflammation","COX,Immunology & Inflammation related,Interleukins,PGES","Immunology & Inflammation","Veratric acid (3,4-Dimethoxybenzoic acid), a simple benzoic acid derived from plants and fruits, has anti-oxidant, anti-inflammation, and blood pressure-lowering effects. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.",182.17,"93-07-2",36,197.62,0,0,"http://selleckchem.com/products/veratric-acid.html","C9H10O4","free base","3,4-Dimethoxybenzoic acid","COC1=C(OC)C=C(C=C1)C(O)=O",1.426,3,0,3]
["S3970","Vindoline","g4","L1300-14","in 10mM DMSO","DMF",null,null,"Others","Microtubule Associated","Cytoskeletal Signaling","Vindoline is a chemical precursor to vinblastine and exhibits antimitotic activity by inhibiting microtubule assembly.",456.53,"2182-14-1",91,199.33,0,0,"http://selleckchem.com/products/vindoline.html","C25H32N2O6","free base","N/A","CCC12C=CCN3CCC4(C(N(C)C5=C4C=CC(=C5)OC)C(O)(C1OC(C)=O)C(=O)OC)C23",1.935,5,0,6]
["S3971","Fusidine","h4","L1300-14","in 10mM DMSO","CFDA",null,null,"Infection","Antibiotics","Microbiology","Fusidine (Fusidic Acid), isolated from Fusidium coccineum, is a steroidal antibiotic that inhibits protein synthesis.",516.71,"6990-06-3",100,193.53,0,0,"http://selleckchem.com/products/fusidine.html","C31H48O6","free base","Fusidic Acid","CC1C(O)CCC2(C)C1CCC3(C)C2C(O)CC4\\C(C(CC34C)OC(C)=O)=C(/CCC=C(C)C)C(O)=O",5.097,3,2,6]
["S3974","(+)-Catechin hydrate","a5","L1300-14","in 10mM DMSO",null,"BP2019;EP9.2",null,"Metabolic Disease","COX","Immunology & Inflammation","(+)-Catechin hydrate is a plant derived polyphenolic anti-oxidants with phytotoxic properties. (+)-Catechin hydrate is a frequent component of traditional herbal remedies, such as Uncaria rhynchophylla.  (+)-Catechin hydrate inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.",290.27,"225937-10-0",58,199.81,0,0,"http://selleckchem.com/products/catechin-hydrate.html","C15H14O6.xH2O","hydrate","N/A","OC1CC2=C(OC1C3=CC(=C(O)C=C3)O)C=C(O)C=C2O",2.021,1,5,1]
["S3975","Protocatechuic acid","b5","L1300-14","in 10mM DMSO",null,"USP42-NF37",null,"Cancer","Apoptosis related","Apoptosis","Protocatechuic acid (PCA, 3,4-Dihydroxybenzoic acid, Protocatechuate), a dihydroxybenzoic acid, is a type of widely distributed naturally occurring phenolic acid.",154.12,"99-50-3",30,194.65,0,0,"http://selleckchem.com/products/protocatechuic-acid.html","C7H6O4","free base","3,4-Dihydroxybenzoic acid, Protocatechuate","OC(=O)C1=CC(=C(O)C=C1)O",0.975,1,2,1]
["S3977","(-)-Borneol","c5","L1300-14","in 10mM DMSO",null,"EP9.2;BP2017;Martindale:The Extra Pharmacopoeia",null,"Immunology/Inflammation","GABA Receptor","Neuronal Signaling","(-)-Borneol (L-Borneol), one of enantiomers of borneol, has a camphoraceous and evident woody odor. (-)-Borneol has a highly efficacious positive modulating action at GABA receptor with an EC50 of 237 μM.",154.25,"464-45-9",30,194.49,0,0,"http://selleckchem.com/products/l-borneol.html","C10H18O","free base","L-Borneol","CC1(C)C2CCC1(C)C(O)C2",1.975,0,1,0]
["S3979","Zinc Undecylenate","d5","L1300-14","in 10mM DMSO","CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,USP40-NF35,IP2010",null,"Infection","Fungal","Microbiology","Zinc Undecylenate (Zinc diundec-10-enoate, Zinc 10-undecenoate) is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.",431.92,"557-08-4",36,83.35,0,0,"http://selleckchem.com/products/zinc-undecylenate.html","C22H38O4Zn","zinc salt","Zinc diundec-10-enoate, Zinc 10-undecenoate","[Zn++].[O-]C(=O)CCCCCCCCC=C.[O-]C(=O)CCCCCCCCC=C",4.494,0,0,18]
["S3980","Pyridoxine","e5","L1300-14","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","080572,080581,080618,080669,080761,083760,083771,083772,087967,204879","Neurological Disease","Vitamin","Metabolism","Pyridoxine (Pyridoxol, Vitamin B6, Gravidox), also known as vitamin B6, is a form of vitamin B6 found commonly in food and used as dietary supplement. It is a cofactor for both glutamic acid decarboxylase and GABA transaminase.",169.18,"65-23-6",33,195.06,0,0,"http://selleckchem.com/products/pyridoxine.html","C8H11NO3","free base","Pyridoxol, Vitamin B6, Gravidox","CC1=NC=C(CO)C(=C1O)CO",-0.49,1,3,2]
["S3982","Batyl alcohol","f5","L1300-14","in 10mM DMSO","CFDA",null,null,"Hematology","Immunology & Inflammation related","Immunology & Inflammation","Batyl alcohol (Batilol, Stearyl monoglyceride, 1-O-Octadecylglycerol, Batilolum), isolated from shark liver oil, is also present in yellow bone marrow of animals and has been described as an inflammatory agent.",344.57,"544-62-7",68,197.35,0,0,"http://selleckchem.com/products/batyl-alcohol.html","C21H44O3","free base","Batilol, Stearyl monoglyceride, 1-O-Octadecylglycerol, Batilolum","CCCCCCCCCCCCCCCCCCOCC(O)CO",6.715,1,2,20]
["S3983","Caryophyllene oxide","g5","L1300-14","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Others","Others","Caryophyllene oxide, an oxygenated terpenoid existed in many plant essential oil, is well known as preservative in food, drugs and cosmetics with anti-inflammatory, anti-carcinogenic and skin penetration enhancing  properties.",220.35,"1139-30-6",44,199.68,"<1",0,"http://selleckchem.com/products/caryophyllene-oxide.html","C15H24O","free base","N/A","CC1(C)CC2C1CCC3(C)OC3CCC2=C",3.519,1,0,0]
["S3984","Nordihydroguaiaretic acid (NDGA)","h5","L1300-14","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Others","Apoptosis related,Autophagy,Epigenetic Reader Domain,Ferroptosis,HER2,IGF-1R,Lipoxygenase","Metabolism","Nordihydroguaiaretic acid (NDGA) is a phenolic antioxidant found in the leaves and twigs of the evergreen desert shrub, Larrea tridentata (Sesse and Moc. ex DC) Coville (creosote bush). It is a recognized inhibitor of lipoxygenase (LOX) and has antioxidant and free radical scavenging properties. Nordihydroguaiaretic acid (NDGA) is a cytotoxic insulin-like growth factor-I receptor (IGF-1R)/HER2 inhibitor and induces apoptosis.",302.36,"500-38-9",60,198.44,"<1",0,"http://selleckchem.com/products/nordihydroguaiaretic-acid.html","C18H22O4","free base","N/A","CC(CC1=CC=C(O)C(=C1)O)C(C)CC2=CC=C(O)C(=C2)O",4.708,0,4,5]
["S3985","Methyl 4-hydroxybenzoate","a6","L1300-14","in 10mM DMSO",null,"BP2019;EP9.2",null,"Immunology","Fungal","Microbiology","Methyl 4-hydroxybenzoate (Methylparaben, Methyl p-hydroxybenzoate, Nipagin) is an anti-fungal agent often used in a variety of cosmetics, personal-care products and food preservatives.",152.15,"99-76-3",30,197.17,0,0,"http://selleckchem.com/products/methyl-4-hydroxybenzoate.html","C8H8O3","free base","Methylparaben, Methyl paraben, Methyl p-hydroxybenzoate, Nipagin, Methyl parahydroxybenzoate","COC(=O)C1=CC=C(O)C=C1",1.443,2,1,2]
["S3986","L-Arabinose","b6","L1300-14","in 10mM DMSO","DMF","BP2019;EP9.2",null,"Metabolic Disease","Others","Others","L-Arabinose (L-Ara) is a plant saccharide that is not found in animals. It is a component of cell wall and may be useful as a natural pharmaceutical.",150.13,"87-72-9",30,199.83,0,0,"http://selleckchem.com/products/l-arabinose.html","C5H10O5","free base","L-Ara","OC1COC(O)C(O)C1O",-2.003,1,3,0]
["S3987","L-Tryptophan","c6","L1300-14","in 10mM DMSO","DMF,CFDA,NDC","USP42-NF37,KP Ⅹ,JP17",null,"Psychotic disorders","Others","Others","L-tryprophan is an essential amino acid that acts like a natural mood regulator that is necessary for normal growth in infants and for nitrogen balance in adults.",204.23,"73-22-3",11,53.86,0,0,"http://selleckchem.com/products/l-tryptophan.html","C11H12N2O2","free base","N/A","NC(CC1=C[NH]C2=C1C=CC=C2)C(O)=O",-1.312,1,2,3]
["S3988","Theophylline-7-acetic acid","d6","L1300-14","in 10mM DMSO","FDA",null,null,"Others","Adenosine Receptor","GPCR & G Protein","Theophylline-7-acetic acid (Acefylline, acetyloxytheophylline, Carboxymethyltheophylline), acting as an adenosine receptor antagonist, is a stimulant drug of the xanthine chemical class.",238.2,"652-37-9",47,197.31,0,0,"http://selleckchem.com/products/theophylline-7-acetic.html","C9H10N4O4","free base","Acefylline, acetyloxytheophylline, Carboxymethyltheophylline","CN1C(=O)N(C)C2=C([N](CC(O)=O)C=N2)C1=O",-0.619,4,0,2]
["S3992","D-(+)-Trehalose dihydrate","f6","L1300-14","in 10mM DMSO",null,"EP9.2;JP17;USP40-NF35;BP2017",null,"Others","Others","Others","Trehalose is a non-reducing sugar. It is thought to provide plants and animals with the ability to withstanding periods of dehydration.",378.33,"6138-23-4",75,198.24,0,0,"http://selleckchem.com/products/d-trehalose-dihyd.html","C12H22O11.2H2O","dihydrate","N/A","O.O.OCC1OC(OC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O",-4.675,3,8,4]
["S3995","Guaiazulene","g6","L1300-14","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017",null,"Inflammation","Others","Others","Guaiazulene (Azulon, Vetivazulen) is a bicyclic sesquiterpene that is a constituent of some essential oils, mainly oil of guaiac and chamomile oil, which also serve as its commercial sources.",198.3,"489-84-9",39,196.67,0,0,"http://selleckchem.com/products/guaiazulene.html","C15H18","free base","Azulon, Vetivazulen","CC(C)C1=CC2=C(C)C=CC2=C(C)C=C1",4.905,0,0,1]
["S3996","Thioctic acid","h6","L1300-14","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017",null,"Nutritional support","Others","Others","Thioctic acid (DL-α-Lipoic acid) is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form., Thioctic acid (DL-α-Lipoic acid)是环状二硫抗氧化剂，可与其还原性二硫酚形式相互转换。",206.33,"1077-28-7",41,198.71,0,0,"http://selleckchem.com/products/thioctic-acid.html","C8H14O2S2","free base","DL-α-Lipoic Acid","OC(=O)CCCCC1CCSS1",2.258,1,0,5]
["S3997","Oxaceprol","a7","L1300-14","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Oxaceprol (N-acetyl-L-hydroxyproline) is an anti-inflammatory drug used in the treatment of osteoarthritis.",173.17,"33996-33-7",34,196.34,0,0,"http://selleckchem.com/products/oxaceprol.html","C7H11NO4","free base","N-acetyl-L-hydroxyproline","CC(=O)N1CC(O)CC1C(O)=O",-1.434,2,1,1]
["S3998","(+)-α-Lipoic acid","b7","L1300-14","in 10mM DMSO","CFDA","USP36-NF31",null,"Endocrinology/Metabolic Disease/Neurological Disease","LTR,NF-κB","NF-κB","(+)-α-Lipoic acid ((R)-(+)-α-Lipoic acid, α-Lipoic acid, Alpha-Lipoic acid), a physiological form of thioctic acid, is a strong antioxidant that relieves diabetic neuropathic symptoms. It shows superior antioxidative effects to its racemate. R(+)-α-lipoic acid is an essential cofactor of mitochondrial enzyme complexes. R(+)-α-lipoic acid inhibits NF-κB-dependent HIV-1 LTR activation.",206.33,"1200-22-2",41,198.71,0,0,"http://selleckchem.com/products/alpha-lipoic-acid.html","C8H14O2S2","free base","(R)-(+)-α-Lipoic acid, α-Lipoic acid, Alpha-Lipoic acid","OC(=O)CCCCC1CCSS1",2.258,1,0,5]
["S3999","α-santonin","c7","L1300-14","in 10mM DMSO",null,"JP17",null,"Infection","Parasite","Microbiology","α-santonin, a naturally occurring sesquiterpene lactone, is a potent antiparasitic agent.",246.3,"481-06-1",49,198.94,0,0,"http://selleckchem.com/products/alpha-santonin.html","C15H18O3","free base","N/A","CC1C2CCC3(C)C=CC(=O)C(=C3C2OC1=O)C",2.601,3,0,0]
["S4000","Pergolide Mesylate","d7","L1300-14","in 10mM DMSO","FDA,DMF","USP42-NF37","076061,076094","Neurological Disease","Dopamine Receptor","Neuronal Signaling","Pergolide Mesylate is an antiparkinsonian agent which functions as a dopaminergic agonist.",410.59,"66104-23-2",10,24.36,82,199.71,"http://selleckchem.com/products/Pergolide-mesylate.html","C20H30N2O3S2","Mesylate","LY127809","CCCN1CC(CSC)CC2C1CC3=C[NH]C4=C3C2=CC=C4.C[S](O)(=O)=O",3.696,0,1,4]
["S4001","Cabozantinib malate","e7","L1300-14","in 10mM DMSO","FDA,DMF",null,"208692,203756","Cancer","Apoptosis related,Axl,c-Kit,c-Met,c-RET,FLT3,VEGFR","Protein Tyrosine Kinase","Cabozantinib malate (XL184) is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret (c-Ret), Kit (c-Kit), Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively. Cabozantinib malate (XL184) induces apoptosis.",635.59,"1140909-48-3",100,157.33,"<1",0,"http://selleckchem.com/products/cabozantinib-malate.html","C28H24FN3O5.C4H6O5","Malate","XL184","COC1=CC2=C(C=C1OC)C(=CC=N2)OC3=CC=C(NC(=O)C4(CC4)C(=O)NC5=CC=C(F)C=C5)C=C3.OC(CC(O)=O)C(O)=O",3.331,8,3,11]
["S4002","Sitagliptin phosphate monohydrate","f7","L1300-14","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017",null,"Endocrinology/Metabolic Disease","DPP","Metabolism","Sitagliptin phosphate monohydrate (MK-0431) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.",523.32,"654671-77-9",100,191.09,41,78.35,"https://www.selleckchem.com/products/sitagliptin-phosphate-monohydrate.html","C16H15F6N5O.H3PO4.H2O","phosphate &monohydrate","MK-0431","O.NC(CC(=O)N1CC[N]2C(=NN=C2C(F)(F)F)C1)CC3=C(F)C=C(F)C(=C3)F.O[P](O)(O)=O",1.254,3,1,5]
["S4003","Lithocholic acid","g7","L1300-14","in 10mM DMSO",null,"USP42-NF37",null,"Others","FXR","Metabolism","Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity, its toxic effect can be protected after it activates the vitamin D receptor, PXR and FXR.",376.57,"434-13-9",75,199.17,"<1",0,"http://selleckchem.com/products/lithocholic-acid.html","C24H40O3","free base","N/A","CC(CCC(O)=O)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C",5.184,1,1,4]
["S4004","Ethambutol 2HCl","h7","L1300-14","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","075095,076057,078939","Infection","Bacterial","Microbiology","Ethambutol 2HCl (CL40881) is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.",277.23,"1070-11-7",56,202,56,202,"http://selleckchem.com/products/ethambutol-hcl.html","C10H24N2O2.2HCl","Dihydrochloride","CL40881","Cl.Cl.CCC(CO)NCCNC(CC)CO",0.874,0,4,9]
["S4007","Pentamidine isethionate","a8","L1300-14","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37,IP2010","073479,073617,074303,206666,206667","Infection/Parasitology","phosphatase","Metabolism","Pentamidine is an inhibitor of PRL Phosphatases and also inhibits synthesis of DNA, RNA and protein.",592.68,"140-64-7",100,168.73,100,168.73,"http://selleckchem.com/products/pentamidine-isethionate.html","C19H24N4O2.2C2H6O4S","isethionate","N/A","NC(=N)C1=CC=C(OCCCCCOC2=CC=C(C=C2)C(N)=N)C=C1.OCC[S](O)(=O)=O.OCC[S](O)(=O)=O",0.751,2,4,14]
["S4009","Mirabegron","b8","L1300-14","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"209413,209446,209488","Others","Adrenergic Receptor","Neuronal Signaling","Mirabegron (YM 178) is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.",396.51,"223673-61-8",79,199.24,"<1",0,"http://selleckchem.com/products/mirabegron-ym178.html","C21H24N4O2S","free base","YM 178","NC1=NC(=CS1)CC(=O)NC2=CC=C(CCNCC(O)C3=CC=CC=C3)C=C2",2.26,2,4,9]
["S4010","Acebutolol HCl","c8","L1300-14","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,IP2010","074007,074288,075047","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Acebutolol is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias.",372.89,"34381-68-5",75,201.13,75,201.13,"http://selleckchem.com/products/acebutolol-hcl.html","C18H28N2O4.HCl","Hydrochloride","N/A","Cl.CCCC(=O)NC1=CC(=C(OCC(O)CNC(C)C)C=C1)C(C)=O",1.997,3,3,10]
["S4011","Ampiroxicam","d8","L1300-14","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Inflammation","COX","Neuronal Signaling","Ampiroxicam (CP 65703) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.",447.46,"99464-64-9",90,201.14,"<1",0,"http://selleckchem.com/products/ampiroxicam.html","C20H21N3O7S","free base","CP 65703","CCOC(=O)OC(C)OC1=C(N(C)[S](=O)(=O)C2=C1C=CC=C2)C(=O)NC3=NC=CC=C3",1.718,8,1,8]
["S4012","Desloratadine","e8","L1300-14","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","078351,078352,078353,078355,078357,078359,078361,078362,078364,078365,078367,202592,202936","Immunology/Inflammation","Histamine Receptor","Neuronal Signaling","Desloratadine (SCH-34117, NSC 675447) is a potent antagonist for  human histamine H1 receptor with IC50 of 51 nM.",310.82,"100643-71-8",26,83.65,"<1",0,"http://selleckchem.com/products/desloratadine.html","C19H19ClN2","free base","SCH-34117, NSC 675447","ClC1=CC2=C(C=C1)C(=C3CCNCC3)C4=C(CC2)C=CC=N4",4.213,1,1,0]
["S4014","Hyoscyamine","f8","L1300-14","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2013,IP2010",null,"Inflammation/Neurological Disease","AChR","Neuronal Signaling","Hyoscyamine (Daturine) is an AChR inhibitor with IC50 of 7.5 nM.",289.37,"101-31-5",58,200.44,"<1",0,"http://selleckchem.com/products/hyoscyamine-daturine.html","C17H23NO3","free base","Daturine","CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",1.721,2,1,5]
["S4017","Allylthiourea","g8","L1300-14","in 10mM DMSO","NDC",null,null,"Others","ROS","Immunology & Inflammation","Allylthiourea is a metabolic inhibitor that selective inhibits ammonia oxidation.",116.18,"109-57-9",23,197.97,"<1",0,"http://selleckchem.com/products/allylthiourea.html","C4H8N2S","free base","N/A","NC(=S)NCC=C",0.842,0,2,3]
["S4018","Sennoside B","h8","L1300-14","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Gastroenterology","PDGFR","Protein Tyrosine Kinase","Sennoside B, a kind of irritant laxative isolated from rhei rhizome, inhibits PDGF-stimulated cell proliferation., Sennoside B，一种从大黄根茎中分离得到的刺激性泻药，抑制PDGF刺激的细胞增殖。",862.74,"128-57-4",100,115.91,"<1",0,"http://selleckchem.com/products/sennoside-b.html","C42H38O20","Free Base","N/A","OCC1OC(OC2=CC=CC3=C2C(=O)C4=C(O)C=C(C=C4C3C5C6=C(C(=O)C7=C(O)C=C(C=C57)C(O)=O)C(=CC=C6)OC8OC(CO)C(O)C(O)C8O)C(O)=O)C(O)C(O)C1O",0.409,8,10,9]
["S4019","Avanafil","a9","L1300-14","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"202276","Others","PDE","Metabolism","Avanafil is a highly selective PDE5 inhibitor with IC50 of 5.2 nM, >121-fold selectivity over other PDEs.",483.95,"330784-47-9",97,200.43,"<1",0,"http://selleckchem.com/products/avanafil.html","C23H26ClN7O3","free base","N/A","COC1=C(Cl)C=C(CNC2=C(C=NC(=N2)N3CCCC3CO)C(=O)NCC4=NC=CC=N4)C=C1",2.165,6,3,9]
["S4020","Sodium Picosulfate","b9","L1300-14","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,JP17,BP2017","205743","Gastroenterology","Others","Others","Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion.",481.41,"10040-45-6",96,199.41,96,199.41,"http://selleckchem.com/products/sodium-picosulfate.html","C18H15NO8S2.2Na","Sodium Salt","N/A","[Na+].[Na+].[O-][S](=O)(=O)OC1=CC=C(C=C1)C(C2=CC=C(O[S]([O-])(=O)=O)C=C2)C3=CC=CC=N3",-1.604,3,0,7]
["S4021","Tolcapone","c9","L1300-14","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","204584,208937","Neurological Disease","COMT,Histone Methyltransferase,Transferase","Metabolism","Tolcapone (Ro 40-7592) is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with Ki of 30 nM.",273.24,"134308-13-7",55,201.29,"<1",0,"http://selleckchem.com/products/tolcapone.html","C14H11NO5","free base","Ro 40-7592","CC1=CC=C(C=C1)C(=O)C2=CC(=C(O)C(=C2)[N+]([O-])=O)O",3.13,1,2,3]
["S4022","Probenecid","d9","L1300-14","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","083740,084211,084442,086150,086917","Infection/Inflammation/Metabolic Disease","Taste Receptor,TRP Channel","Transmembrane Transporters","Probenecid (Benemid) is a classical competitive inhibitor of organic anion transport, which is also a TRPV2 agonist and an inhibitor of TAS2R16. Probenecid is also a clinically used broad-spectrum Pannexin1 (Panx1) blocker.",285.36,"57-66-9",57,199.75,"<1",0,"http://selleckchem.com/products/probenecid-benemid.html","C13H19NO4S","free base","Benemid","CCCN(CCC)[S](=O)(=O)C1=CC=C(C=C1)C(O)=O",2.321,3,0,7]
["S4023","Procaine HCl","e9","L1300-14","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,EP8.8,Ph.Int_6th,JP17,BP2017,IP2010,USP35-NF30","080384,080415,080416,080421,080658,080711,080756,083315,083535,086202","Neurological Disease","AChR,NMDAR,Sodium Channel","Transmembrane Transporters","Procaine (Novocaine) is an inhibitor of sodium channel, NMDA receptor and nAChR with IC50 of 60 μM, 0.296 mM and 45.5 μM, which is also an inhibitor of 5-HT3 with KD of 1.7 μM.",272.77,"51-05-8",55,201.64,55,201.64,"http://selleckchem.com/products/procaine-novocaine-hcl.html","C13H20N2O2.HCl","HCl","Novocaine HCl","Cl.CCN(CC)CCOC(=O)C1=CC=C(N)C=C1",2.157,2,1,7]
["S4024","Homatropine Methylbromide","f9","L1300-14","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,Ph.Int_6th,BP2017","086310,086308,086309","Neurological Disease","AChR","Neuronal Signaling","Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.",370.28,"80-49-9",74,199.85,74,199.85,"http://selleckchem.com/products/homatropine-methylbromide.html","C17H24NO3.Br","quaternary-N bromide salt","N/A","[Br-].C[N+]1(C)C2CCC1CC(C2)OC(=O)C(O)C3=CC=CC=C3",-2.076,2,1,4]
["S4025","Homatropine Bromide","g9","L1300-14","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","040295;091528;207176","Ophthalmology","AChR","Neuronal Signaling","Homatropine Bromide is an muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.",356.25,"51-56-9",71,199.3,71,199.3,"http://selleckchem.com/products/homatropine-bromide.html","C16H21NO3.HBr","quaternary-N bromide salt","N/A","Br.CN1C2CCC1CC(C2)OC(=O)C(O)C3=CC=CC=C3",2.188,2,1,4]
["S4026","Hydroxyzine 2HCl","h9","L1300-14","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.5,JP17,BP2017","040010,040391,040559,040562,040563,040574,040579,040580,040604,040786,040804,040805,040808,040812,040840,040841,040842,040899,081054,081149,081150,081151,085247,085551,085778,085779,086258,086821,086822,086827,086829,086836,086880,087216,087245,087246,087273,087274,087294,087310,087329,087408,087410,087411,087416,087546,087591,087592,087593,087595,087596,087602,087603,087604,087730,087819,087820,087821,087822,087857,087860,087862,087871,088120,088121,088122,088184,088185,088348,088349,088350,088409,088529,088540,088551,088617,088618,088619,088785,088794,088795,088796,088862,088881,089071,089072,089073,089106,089107,089117,089121,089122,089123,089366,089381,089382,089383,089396,091176,201674,204279,207120,207121,207122,210634","Immunology/Psychotic disorders","Histamine Receptor","Neuronal Signaling","Hydroxyzine is a histamine H1-receptor antagonist, inhibits binding of [3H]pyrilamine/[3H]desloratadine to human histamine H1 receptor with IC50 of 10 nM/19 nM.",447.83,"2192-20-3",90,200.97,90,200.97,"http://selleckchem.com/products/hydroxyzine-2hcl.html","C21H27ClN2O2.2HCl","dihydrochloride","N/A","Cl.Cl.OCCOCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3",4.231,1,1,8]
["S4031","Aclidinium Bromide","a10","L1300-14","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"202450","Immunology/Inflammation/Respiratory Disease","AChR","Neuronal Signaling","Aclidinium Bromide (LAS 34273, LAS-W 330) inhibits human muscarinic AChR M1, M2, M3, M4 and M5 with Ki of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM and 0.16 nM, respectively.",564.55,"320345-99-1",113,200.16,"<1",0,"http://selleckchem.com/products/aclidinium-bromide.html","C26H30NO4S2.Br","quaternary-N bromide salt","LAS 34273, LAS-W 330","[Br-].OC(C(=O)OC1C[N+]2(CCCOC3=CC=CC=C3)CCC1CC2)(C4=CC=CS4)C5=CC=CS5",0.979,3,0,10]
["S4034","Diphemanil Methylsulfate","b10","L1300-14","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia","008114","Gastroenterology","AChR","Neuronal Signaling","Diphemanil Methylsulfate is a quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors (mAchR).",389.51,"62-97-5",25,64.18,28,71.89,"http://selleckchem.com/products/diphemanil-methylsulfate.html","C20H24N.CH3O4S","Methylsulfate","N/A","CO[S]([O-])(=O)=O.C[N+]1(C)CC[C](CC1)=[C](C2=CC=CC=C2)C3=CC=CC=C3",0.038,1,0,3]
["S4037","Doxapram HCl","c10","L1300-14","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","073529,076266","Inflammation/Respiratory Disease","Potassium Channel","Transmembrane Transporters","Doxapram HCl inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.",432.98,"7081-53-0",87,200.93,25,57.74,"http://selleckchem.com/products/doxapram-hcl.html","C24H30N2O2.HCl.H2O","HCl","N/A","O.Cl.CCN1CC(CCN2CCOCC2)C(C1=O)(C3=CC=CC=C3)C4=CC=CC=C4",3.218,2,0,6]
["S4038","Dibucaine HCl","d10","L1300-14","in 10mM DMSO","FDA,NDC","USP42-NF37,KP Ⅹ,JP17","006203","Neurological Disease","Sodium Channel","Transmembrane Transporters","Dibucaine HCl (Cinchocaine) is a local anesthetics.",379.92,"61-12-1",76,200.04,76,200.04,"http://selleckchem.com/products/dibucaine-cinchocaine-hcl.html","C20H29N3O2.HCl","hydrochloride","Cinchocaine HCl","Cl.CCCCOC1=CC(=C2C=CC=CC2=N1)C(=O)NCCN(CC)CC",4.294,3,1,10]
["S4039","Methazolamide","e10","L1300-14","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","040001,040011,040036,040062,040102,207438","Ophthalmology","Carbonic Anhydrase","Metabolism","Methazolamide (CL 8490) is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively.",236.27,"554-57-4",47,198.92,"<1",0,"http://selleckchem.com/products/methazolamide.html","C5H8N4O3S2","free base","CL 8490","CN1N=C(SC1=NC(C)=O)[S](N)(=O)=O",0.03,5,1,1]
["S4040","Norethindrone","f10","L1300-14","in 10mM DMSO","FDA,DMF,NDC","CP2005,USP42-NF37,IP2010","091209,091325,200961,200980,201483,202014,202260,206807","Endocrinology","Others,0","Others","Norethindrone (Norethisterone) is a synthetic progestin, which mimic the actions of the endogenous ovarian hormone progesterone.",298.42,"68-22-4",60,201.06,"<1",0,"http://selleckchem.com/products/norethindrone-norethisterone.html","C20H26O2","free base","Norethisterone","CC12CCC3C(CCC4=CC(=O)CCC34)C1CCC2(O)C#C",4.315,1,0,0]
["S4041","Olsalazine Sodium","g10","L1300-14","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017","019715","Infection","Anti-infection","Microbiology","Olsalazine Sodium is an anti-inflammatory prodrug, which consists of two 5-ASA moieties linked by an azo bond.",346.2,"6054-98-4",4,11.55,41,118.43,"http://selleckchem.com/products/olsalazine-sodium.html","C14H8N2O6.2Na","Disodium Salt","N/A","[Na+].[Na+].OC1=CC=C(C=C1C([O-])=O)N=NC2=CC=C(O)C(=C2)C([O-])=O",0.026,2,2,4]
["S4042","Nafcillin Sodium","h10","L1300-14","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP39-NF34","061984,062527,062732,062844,063008,090002,090005,090560,090580,090582,091613,091614,200002","Infection","β-lactamase","Microbiology","Nafcillin sodium (CL 8491) reversibly inhibits β-lactamase with Kd of 33 mM.",454.47,"7177-50-6",91,200.23,91,200.23,"http://selleckchem.com/products/nafcillin-sodium.html","C21H21N2O5S.H2O.Na","sodium Salt","CL 8491","O.CCOC1=C(C(=O)NC2C3SC(C)(C)C(N3C2=O)C(=O)O[Na])C4=C(C=CC=C4)C=C1",2.213,5,1,6]
["S4043","Tetrahydrozoline HCl","a11","L1300-14","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ","086576","Ophthalmology","Adrenergic Receptor","Neuronal Signaling","Tetrahydrozoline (Tetryzoline) HCl is an imidazoline derivative with alpha receptor agonist activity.",236.74,"522-48-5",12,50.69,47,198.53,"http://selleckchem.com/products/tetrahydrozoline-hcl.html","C13H16N2.HCl","hydrochloride","Tetryzoline HCl","Cl.C1CC(C2=NCCN2)C3=CC=CC=C3C1",2.567,1,1,1]
["S4044","Toltrazuril","b11","L1300-14","in 10mM DMSO","EMA","Martindale:The Extra Pharmacopoeia",null,"Parasite","Parasite","Microbiology","Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.",425.38,"69004-03-1",85,199.82,"<1",0,"http://selleckchem.com/products/toltrazuril.html","C18H14F3N3O4S","free base","N/A","CN1C(=O)NC(=O)N(C1=O)C2=CC(=C(OC3=CC=C(SC(F)(F)F)C=C3)C=C2)C",6.052,4,1,5]
["S4045","Pheniramine Maleate","c11","L1300-14","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,BP2017,USP39-NF34,IP2010","078208,202795","Immunology/Inflammation","Histamine Receptor","Neuronal Signaling","Pheniramine Maleate is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.",356.42,"132-20-7",71,199.2,71,199.2,"http://selleckchem.com/products/pheniramine-maleate.html","C16H20N2.C4H4O4","Maleate","N/A","CN(C)CCC(C1=CC=CC=C1)C2=NC=CC=C2.OC(=O)\\C=C/C(O)=O",0.036,3,0,7]
["S4046","Estradiol Cypionate","d11","L1300-14","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37,Ph.Int_6th","085620,089310","Angiology/Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estradiol cypionate is the 17 β-cyclopentylpropinate ester of estradiol, which inhibits ET-1 synthesis via estrogen receptor.",396.56,"313-06-4",79,199.21,"<1",0,"http://selleckchem.com/products/estradiol-cypionate.html","C26H36O3","free base","N/A","CC12CCC3C(CCC4=CC(=CC=C34)O)C1CCC2OC(=O)CCC5CCCC5",6.589,2,1,5]
["S4047","Bisacodyl","e11","L1300-14","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017,IP2010","021551,202217,090197","Gastroenterology","Others","Others","Bisacodyl (INN) is a stimulant laxative drug that works directly on the colon to produce a bowel movement.",361.39,"603-50-9",72,199.23,"<1",0,"http://selleckchem.com/products/bisacodyl.html","C22H19NO4","free base","N/A","CC(=O)OC1=CC=C(C=C1)C(C2=CC=C(OC(C)=O)C=C2)C3=CC=CC=N3",3.691,5,0,7]
["S4048","Carbimazole","f11","L1300-14","in 10mM DMSO","CFDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017,IP2010",null,"Metabolic Disease","TSH Receptor","Endocrinology & Hormones","Carbimazole is an imidazole antithyroid agent.",186.23,"22232-54-8",38,204.05,"<1",0,"http://selleckchem.com/products/carbimazole.html","C7H10N2O2S","free base","N/A","CCOC(=O)N1C=CN(C)C1=S",1.202,2,0,2]
["S4049","Valdecoxib","g11","L1300-14","in 10mM DMSO","FDA,EMA","Martindale:The Extra Pharmacopoeia","021341","Inflammation/Neurological Disease","COX","Neuronal Signaling","Valdecoxib is a potent and selective inhibitor of COX-2 with IC50 of 5 nM.",314.36,"181695-72-7",63,200.41,"<1",0,"http://selleckchem.com/products/valdecoxib.html","C16H14N2O3S","free base","N/A","CC1=C(C2=CC=C(C=C2)[S](N)(=O)=O)C(=NO1)C3=CC=CC=C3",2.6,4,1,3]
["S4050","Valganciclovir HCl","h11","L1300-14","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","200790,203511,204750,205166,205220,206876,209672","Infection","CMV","Microbiology","Valganciclovir HCl is a prodrug for ganciclovir with antiviral activity used to treat cytomegalovirus infections.",390.82,"175865-59-5",78,199.58,78,199.58,"http://selleckchem.com/products/valganciclovir-hcl.html","C14H22N6O5.HCl","Hydrochloride","N/A","Cl.CC(C)C(N)C(=O)OCC(CO)OCN1C=NC2C1N=C(N)NC2=O",-1.444,6,4,9]
["S4051","Nabumetone","a2","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017","075179,075189,075280,075590,076009,078420,078671,079093,090427,090445,090516,091083","Inflammation","COX","Neuronal Signaling","Nabumetone (BRL-14777) is a non-steroidal anti-inflammatory drug and its active metabolite inhibits the COX.",228.29,"42924-53-8",46,201.5,"<1",0,"http://selleckchem.com/products/nabumetone.html","C15H16O2","free base","BRL-14777","COC1=CC=C2C=C(CCC(C)=O)C=CC2=C1",2.943,2,0,4]
["S4053","Sertraline HCl","b2","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,BP2017","075719,076442,076465,076540,076671,076881,076882,076934,077106,077162,077206,077299,077345,077397,077663,077670,077713,077765,077818,077864,077977,078053,078108,078175,078403,078626,078677,078861,202825","Psychotic disorders","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Sertraline HCl (CP-51974-1) is a 5-HT antagonist with Ki of 13 nM.",342.69,"79559-97-0",69,201.35,"<1",0,"http://selleckchem.com/products/sertraline-hcl.html","C17H17Cl2N.HCl","HCl","CP-51974-1 HCl","Cl.CNC1CCC(C2=CC=C(Cl)C(=C2)Cl)C3=C1C=CC=C3",5.378,0,1,2]
["S4054","Spironolactone","c2","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8,KP Ⅹ,JP17,BP2017,IP2010","040353,040424,040750,086809,086898,087078,087086,087108,087265,087554,087634,087648,087687,087952,087998,088053,089364,089424,091426,202187,203253,203512,205936","Endocrinology/Metabolic Disease","Androgen Receptor","Endocrinology & Hormones","Spironolactone is a potent antagonist of the androgen receptor with IC50 of 77 nM.",416.57,"52-01-7",83,199.25,"<1",0,"http://selleckchem.com/products/spironolactone.html","C24H32O4S","free base","N/A","CC(=O)SC1CC2=CC(=O)CCC2(C)C3CCC4(C)C(CCC45CCC(=O)O5)C13",3.731,4,0,2]
["S4056","Retapamulin","d2","L1300-15","in 10mM DMSO","FDA,EMA,NDC","Martindale:The Extra Pharmacopoeia","022055","Infection","Antibiotics","Microbiology","Retapamulin (SB-275833) is a topical antibiotic, which binds to both E. coli and S. aureus ribosomes with similar potencies with Kd of 3 nM.",517.76,"224452-66-8",104,200.87,"<1",0,"http://selleckchem.com/products/retapamulin.html","C30H47NO4S","free base","SB-275833","CC1CCC23CCC(=O)C2C1(C)C(CC(C)(C=C)C(O)C3C)OC(=O)CSC4CC5CCC(C4)N5C",4.154,3,1,6]
["S4057","Methyclothiazide","e2","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","085476,085487,087671,087672,087786,087913,088724,088745,088750,089135,089136,089835,089837","Metabolic Disease","Others","Others","Methyclothiazide is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including heart disease.",360.24,"135-07-9",72,199.87,"<1",0,"http://selleckchem.com/products/methyclothiazide.html","C9H11Cl2N3O4S2","free base","N/A","CN1C(CCl)NC2=CC(=C(C=C2[S]1(=O)=O)[S](N)(=O)=O)Cl",0.808,4,2,2]
["S4058","Ropivacaine HCl","f2","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1","078601,090194,090318,203955,204636,205612,206166,207636,210102","Neurological Disease","Sodium Channel","Transmembrane Transporters","Ropivacaine HCl (LEA-103) is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.",310.86,"98717-15-8",62,199.45,46,147.98,"http://selleckchem.com/products/ropivacaine-hcl.html","C17H26N2O.HCl","HCl","LEA-103 HCl","Cl.CCCN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",4.236,1,1,4]
["S4059","Sodium Nitroprusside Dihydrate","g2","L1300-15","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Others","Others","Sodium Nitroprusside  Dihydrate is a potent vasodilator working through releasing NO spontaneously in blood.",297.95,"13755-38-9",60,201.38,60,201.38,"http://selleckchem.com/products/sodium-nitroprusside-dihydrate.html","C5H4FeN6Na2O3","Dihydrate","N/A","[Na+].[Na+].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N",0.571,1,0,1]
["S4060","Erythromycin Ethylsuccinate","h2","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37,EP9.3,KP Ⅹ,Ph.Int_6th","061904,062055,062177,062200,062231,062256,062558,062559,062674,062847","Infection","Antibiotics,Bacterial","Microbiology","Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.",862.05,"1264-62-6",172,199.52,"<1",0,"http://selleckchem.com/products/erythromycin-ethylsuccinate.html","C43H75NO16","free base","N/A","CCOC(=O)CCC(=O)OC1C(CC(C)OC1OC2C(C)C(OC3CC(C)(OC)C(O)C(C)O3)C(C)C(=O)OC(CC)C(C)(O)C(O)C(C)C(=O)C(C)CC2(C)O)N(C)C",2.591,12,2,14]
["S4061","Levobupivacaine HCl","a3","L1300-15","in 10mM DMSO","FDA,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia","020997","Neurological Disease","Sodium Channel","Transmembrane Transporters","Levobupivacaine HCl ((S)-(-)-Bupivacaine), the pure S(-)-enantiomer of bupivacaine, is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.",324.89,"27262-48-2",64,196.99,64,196.99,"http://selleckchem.com/products/lvobupivacaine-hcl.html","C18H28N2O.HCl","Hydrochloride","(S)-(-)-Bupivacaine HCl","Cl.CCCCN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",4.692,1,1,5]
["S4062","Ronidazole","b3","L1300-15","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Infection/Parasite","Anti-infection","Microbiology","Ronidazole is an antiprotozoal agent.",200.15,"7681-76-7",40,199.85,"<1",0,"http://selleckchem.com/products/ronidazole.html","C6H8N4O4","free base","N/A","C[N]1C(=NC=C1[N+]([O-])=O)COC(N)=O",-0.301,3,1,4]
["S4064","Escitalopram Oxalate","c3","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","076765,077412,077512,077550,077660,077734,077798,078032,078169,078219,078313,078467,078604,078766,078777,079062,079121,090432,090477,090939,202210,202221,202227,202280,202389,202754,203967,205619","Psychotic disorders","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Escitalopram Oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.",414.43,"219861-08-2",83,200.28,25,60.32,"http://selleckchem.com/products/escitalopram-oxalate.html","C20H21FN2O.C2H2O4","Oxalate","N/A","CN(C)CCCC1(OCC2=CC(=CC=C12)C#N)C3=CC=C(F)C=C3.OC(=O)C(O)=O",0.257,3,0,6]
["S4065","Guanabenz Acetate","d3","L1300-15","in 10mM DMSO","FDA,DMF,PMDA","USP42-NF37,JP17","074025,074149,074267,074517","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Guanabenz Acetate (WY-8678) is an selective agonist of α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor with pEC50 of 8.25, 7.01 and ~5, respectively.",291.13,"23256-50-0",58,199.22,"<1",0,"http://selleckchem.com/products/guanabenz-wy-8678-acetate.html","C8H8Cl2N4.C2H4O2","Acetate","WY-8678 Acetate","CC(O)=O.NC(=N)N/N=C/C1=C(Cl)C=CC=C1Cl",1.987,2,2,3]
["S4068","Tinidazole","e3","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,EP9.2,KP Ⅹ,JP17,BP2017,IP2010","201172,202044,202489,203808","Infection/Parasitology","Parasite","Microbiology","Tinidazole (CP12574) is an anti-parasitic drug.",247.27,"19387-91-8",49,198.16,"<1",0,"http://selleckchem.com/products/tinidazole.html","C8H13N3O4S","free base","CP12574","CC[S](=O)(=O)CC[N]1C(=NC=C1[N+]([O-])=O)C",0.149,3,0,5]
["S4070","Guanidine HCl","f3","L1300-15","in 10mM DMSO","FDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","001546","Others","Others","Others","Guanidine HCl (Aminoformamidine), the crystalline compound of strong alkalinity formed by the oxidation of guanine, is a normal product of protein metabolism and a protein denaturant.",95.53,"50-01-1",19,198.89,19,198.89,"http://selleckchem.com/products/guanidine-aminoformamidine-hcl.html","CH5N3.HCl","Hydrochloride","Aminoformamidine HCl","Cl.NC(N)=N",-0.606,0,2,0]
["S4071","Griseofulvin","g3","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.7,KP Ⅹ,Ph.Int_6th,BP2017,JP16,IP2010","065200,065354,065394,065438,091592,202482","Infection","Microtubule Associated","Cytoskeletal Signaling","Griseofulvin, a production from some strains of the mold Penicillium griseofulvumam, is able to inhibit cell mitosis by interfering with microtubule function.",352.77,"126-07-8",50,141.74,"<1",0,"http://selleckchem.com/products/griseofulvin.html","C17H17ClO6","free base","N/A","COC1=CC(=C2C(=O)C3(OC2=C1Cl)C(C)CC(=O)C=C3OC)OC",2.495,6,0,3]
["S4072","Decamethonium Bromide","h3","L1300-15","in 10mM DMSO","FDA",null,"006931","Neurological Disease","AChR","Neuronal Signaling","Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent.",418.29,"541-22-0",34,81.28,84,200.82,"http://selleckchem.com/products/decamethonium-bromide.html","C16H38N2.2Br","Bromide","N/A","[Br-].[Br-].C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C",-3.707,0,0,11]
["S4073","Sodium 4-Aminosalicylate","a4","L1300-15","in 10mM DMSO","FDA,CFDA,DMF","Martindale the Extra Pharmacopoei,EP10.0,USP42-NF37,BP2017,IP2010","080097","Infection","NF-κB","NF-κB","Sodium 4-Aminosalicylate is an antibiotic used to treat tuberculosis via NF-κB inhibition and free radical scavenging.",211.15,"6018-19-5",42,198.91,42,198.91,"http://selleckchem.com/products/aminosalicylate-sodium.html","C7H7NO3.2H2O.Na","Sodium Salt","N/A","[Na+].NC1=CC(=C(C=C1)C([O-])=O)O",-1.003,0,2,1]
["S4075","Zinc Pyrithione","b4","L1300-15","in 10mM DMSO","NDC",null,null,"Inflammation","Fungal,Proton Pump","Transmembrane Transporters","Zinc pyrithione (OM-1563) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.",317.7,"13463-41-7",30,94.43,"<1",0,"http://selleckchem.com/products/zinc-pyrithione.html","C10H8N2O2S2Zn","free base","OM-1563","O1N2C=CC=CC2=[SH][Zn]13ON4C=CC=CC4=[SH]3",0.874,2,0,0]
["S4076","Propranolol HCl","c4","L1300-15","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017,IP2010","016419,070103,070120,070121,070122,070123,070124,070125,070126,070127,070128,070135,070136,070137,070140,070141,070142,070143,070144,070175,070176,070177,070178,070213,070219,070221,070232,070233,070234,070306,070307,070308,070309,070310,070319,070320,070321,070322,070378,070379,070380,070381,070382,070438,070439,070440,070441,070442,070516,070517,070518,070519,070520,070521,070548,070549,070550,070551,070663,070664,070665,070666,070667,070690,070757,070814,070815,070816,070817,070979,071098,071183,071288,071327,071368,071369,071370,071371,071495,071496,071515,071516,071517,071518,071658,071687,071688,071689,071791,071792,071972,071976,071977,071984,071985,072063,072066,072067,072068,072069,072117,072118,072119,072120,072197,072198,072275,072499,072500,072501,072502,075792,075826,076400,077760,078022,078065,078213,078311,078494,078703,078955,090321","Cardiovascular Disease/Neurological Disease/Cancer","Adrenergic Receptor","GPCR & G Protein","Propranolol HCl (AY-64043, ICI-45520, NCS-91523) is a competitive non-selective beta-adrenergic receptors inhibitor.",295.8,"318-98-9",59,199.46,6,20.28,"http://selleckchem.com/products/propranolol-hcl.html","C16H21NO2.HCl","Hydrochloride","AY-64043, ICI-45520, NCS-91523","Cl.CC(C)NCC(O)COC1=CC=CC2=CC=CC=C12",2.922,1,2,6]
["S4077","Mequinol","d4","L1300-15","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia","020922","Others","Others","Others","Mequinol (4-Methoxyphenol) is a depigmentation agent.",124.14,"150-76-5",25,201.39,25,201.39,"http://selleckchem.com/products/mequinol.html","C7H8O2","free base","N/A","COC1=CC=C(O)C=C1",1.571,1,1,1]
["S4078","Mefenamic Acid","e4","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,EP9.8,KP Ⅹ,JP17,BP2017,IP2010","090359,090562,091322,091608","Inflammation/Neurological Disease","COX","Neuronal Signaling","Mefenamic Acid (CI 473, CN-35355) is a competitive inhibitor of COX-1 and COX-2.",241.29,"61-68-7",48,198.93,"<1",0,"http://selleckchem.com/products/mefenamic-acid.html","C15H15NO2","free base","CI 473, CN-35355","CC1=C(C)C(=CC=C1)NC2=CC=CC=C2C(O)=O",3.982,1,1,3]
["S4079","Ticagrelor","f4","L1300-15","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA",null,"208390,208505,208508,208531,208539,208567,208575,208576,208599,210219","Cardiovascular Disease","P2 Receptor","Neuronal Signaling","Ticagrelor (AZD 6140, AR-C 126532XX) is the first reversibly binding oral P2Y12 receptor antagonist with Ki of 2 nM.",522.57,"274693-27-5",100,191.36,"<1",0,"http://selleckchem.com/products/ticagrelor.html","C23H28F2N6O4S","free base","AZD 6140, AR-C 126532XX","CCCSC1=NC2=C(N=N[N]2C3CC(OCCO)C(O)C3O)C(=N1)NC4CC4C5=CC(=C(F)C=C5)F",2.843,5,4,10]
["S4080","Triamterene","g4","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017,IP2010","016042,013174","Cardiovascular Disease/Metabolic Disease","Sodium Channel","Transmembrane Transporters","Triamterene (SKF8542) blocks epithelial Na+ channel (ENaC) in a voltage-dependent manner with IC50 of 4.5 μM.",253.26,"396-01-0",20,78.97,"<1",0,"http://selleckchem.com/products/triamterene.html","C12H11N7","free base","SKF8542","NC1=NC2=C(N=C(C3=CC=CC=C3)C(=N2)N)C(=N1)N",1.017,4,3,1]
["S4081","Sulfacetamide Sodium","h4","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,EP9.1,Ph.Int_6th,BP2017,USP39-NF34","040066,040215,040216,077015,078649,078668,080029,088947,089068,089560","Infection","Anti-infection,Autophagy","Immunology & Inflammation","Sulfacetamide Sodium is an anti-biotic.",236.22,"127-56-0",19,80.43,51,215.9,"http://selleckchem.com/products/sulfacetamide-sodium.html","C8H10N2O3S.Na","Sodium Salt","N/A","[Na+].CC(=O)[N-][S](=O)(=O)C1=CC=C(N)C=C1",-0.118,3,1,2]
["S4082","Spiramycin","a5","L1300-15","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,EP9.2,KP Ⅹ,JP17,BP2017,IP2010",null,"Infection/Parasitology","Antibiotics","Microbiology","Spiramycin (Formacidine) is a 16-membered ring macrolide (antibiotic).",843.05,"8025-81-8",100,118.62,"<1",0,"http://selleckchem.com/products/spiramycin.html","C43H74N2O14","free base","Formacidine","COC1C(O)CC(=O)OC(C)C/C=C/C=C/C(OC2CCC(C(C)O2)N(C)C)C(C)CC(CC=O)C1OC3OC(C)C(OC4CC(C)(O)C(O)C(C)O4)C(C3O)N(C)C",2.049,10,3,11]
["S4083","Vitamin A Acetate","b5","L1300-15","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia,USP39-NF34,BP2015,BP2013",null,"Nutritional support","Vitamin","Metabolism","Vitamin A Acetate (Retinyl, Retinol) is a group of unsaturated nutritional hydrocarbons, that includes retinol, retinal, retinoic acid, and several provitamin A carotenoids, among which beta-carotene is the most important.",328.49,"127-47-9",65,197.88,"<1",0,"http://selleckchem.com/products/vitamin-a-acetate.html","C22H32O2","free base","Retinyl (Retinol) Acetate","CC(=O)OC/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C",5.695,2,0,7]
["S4084","Lomerizine 2HCl","c5","L1300-15","in 10mM DMSO","CFDA,PMDA",null,null,"Neurological Disease/Ophthalmology","Calcium Channel","Transmembrane Transporters","Lomerizine dihydrochloride (KB-2796) is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine.",541.46,"101477-54-7",100,184.69,"<1",0,"http://selleckchem.com/products/lomerizine-hcl.html","C27H30F2N2O3.2HCl","Dihydrochloride","KB-2796","Cl.Cl.COC1=C(OC)C(=C(CN2CCN(CC2)C(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)C=C1)OC",6.182,3,0,8]
["S4085","Levobetaxolol HCl","d5","L1300-15","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia","021114","Ophthalmology","Adrenergic Receptor","GPCR & G Protein","Levobetaxolol (AL 1577A,(S)-Betaxolol hydrochloride) exhibits a higher affinity at cloned human β1 and β2 receptors with Ki value of 0.76 nM and 32.6 nM, respectively.",343.89,"116209-55-3",69,200.65,69,200.65,"http://selleckchem.com/products/levobetaxolol-hcl.html","C18H29NO3.HCl","Hydrochloride","AL 1577A,(S)-Betaxolol hydrochloride","Cl.CC(C)NCC(O)COC1=CC=C(CCOCC2CC2)C=C1",2.959,2,2,11]
["S4086","Loxapine Succinate","e5","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","072062,072204,072205,072206,076762,076868,090695","Psychotic disorders","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Loxapine Succinate(NSC 759578) is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent.",445.9,"27833-64-3",89,199.6,"<1",0,"http://selleckchem.com/products/loxapine-succinate.html","C18H18ClN3O.C4H6O4","Succinate","NSC 759578","CN1CCN(CC1)C2=NC3=C(OC4=C2C=C(Cl)C=C4)C=CC=C3.OC(=O)CCC(O)=O",0.039,4,0,4]
["S4088","Flumethasone","f5","L1300-15","in 10mM DMSO","FDA,DMF",null,"016379","Immunology/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Flumethasone (RS-2177, NSC-54702,Flumetasone) is a glucocorticoid receptor agonist, this complex binds to the nucleus causing a variety of genetic activation and repressions.",410.45,"2135-17-3",82,199.78,"<1",0,"http://selleckchem.com/products/flumethasone.html","C22H28F2O5","free base","RS-2177, NSC-54702,Flumetasone","CC1CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO",1.546,2,2,2]
["S4089","Halobetasol Propionate","g5","L1300-15","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","076872,076903,076994,077001,077109,077123,077227,077721,078162,209978,210566,211464","Immunology","Phospholipase (e.g. PLA)","Metabolism","Halobetasol Propionate (BMY-30056, CGP-14458,Ulobetasol propionate) is an anti-inflammatory and a dermatologic agent commonly used to treat psoriasis. Halobetasol propionate is thought to act by the induction of phospholipase A2 (PLA2) inhibitory proteins.",484.96,"66852-54-8",97,200.02,"<1",0,"http://selleckchem.com/products/halobetasol-propionate.html","C25H31ClF2O5","free base","BMY-30056, CGP-14458,Ulobetasol propionate","CCC(=O)OC1(C(C)CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)CCl",3.797,4,1,5]
["S4090","Fenspiride HCl","h5","L1300-15","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Respiratory Disease","PDE","Metabolism","Fenspiride(Decaspiride) is a bronchodilator with anti-inflammatory properties, inhibiting phosphodiesterase 4 and phosphodiesterase 3 activities with logIC50 values of 4.16 and 3.44, respectively, in human isolated bronchi.",296.79,"5053-08-7",9,30.32,59,198.79,"http://selleckchem.com/products/Fenspiride-hcl.html","C15H20N2O2.HCl","Hydrochloride","Decaspiride","Cl.O=C1NCC2(CCN(CCC3=CC=CC=C3)CC2)O1",2.089,2,1,3]
["S4091","Ifenprodil Tartrate","a6","L1300-15","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Neurological Disease","NMDAR","Neuronal Signaling","Ifenprodil is an atypical noncompetitive antagonist at the NMDA receptor, it interacts with high affinity at a homogeneous population of NMDA receptors in neonatal rat forebrain with IC50 of 0.3 μM.",800.98,"23210-58-4",95,118.6,9,11.24,"http://selleckchem.com/products/ifenprodil-tartrate.html","2(C21H27NO2).C4H6O6","Tartrate","N/A","CC(C(O)C1=CC=C(O)C=C1)N2CCC(CC2)CC3=CC=CC=C3.CC(C(O)C4=CC=C(O)C=C4)N5CCC(CC5)CC6=CC=CC=C6.OC(C(O)C(O)=O)C(O)=O",0.638,2,6,13]
["S4092","Pramoxine HCl","b6","L1300-15","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","086457,089440,083213,083778,085368,085979,085980 ,086195","Neurological Disease","Others","Others","Pramoxine(Pramocaine hydrochloride) is a topical local anesthetic that has been shown to have antipruritic properties.",329.86,"637-58-1",66,200.08,66,200.08,"http://selleckchem.com/products/pramoxine-hcl.html","C17H27NO3.HCl","Hydrochloride","Pramocaine hydrochloride","Cl.CCCCOC1=CC=C(OCCCN2CCOCC2)C=C1",3.396,3,0,9]
["S4095","Difluprednate","c6","L1300-15","in 10mM DMSO","FDA,DMF,PMDA","Martindale:The Extra Pharmacopoeia","022212","Inflammation/Ophthalmology","Others","Others","Difluprednate (difluoroprednisolone butyrate acetate, DFBA, CM 9155) is a synthetic difluorinated prednisolone derivative, it is originally developed for dermatologic applications.",508.55,"23674-86-4",100,196.64,"<1",0,"http://selleckchem.com/products/difluprednate.html","C27H34F2O7","free base","CM 9155","CCCC(=O)OC1(CCC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)COC(C)=O",3.108,6,1,8]
["S4096","Droperidol","d6","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,JP17,BP2017","070992,070993,071645,071750,071754,071755,071941,071942,071981,072018,072019,072020,072021,072123,072272,072335,073520,073521,073523,208197","Neurological Disease","Dopamine Receptor","Neuronal Signaling","Droperidol (NSC 169874,Dehydrobenzperidol) is a potent antagonist of dopamine subtype 2 receptors in the limbic system.",379.43,"548-73-2",76,200.3,"<1",0,"http://selleckchem.com/products/droperidol.html","C22H22FN3O2","free base","NSC 169874,Dehydrobenzperidol","FC1=CC=C(C=C1)C(=O)CCCN2CCC(=CC2)N3C(=O)NC4=C3C=CC=C4",3.049,2,1,6]
["S4098","Halcinonide","e6","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37","017556,017818,017823,017824,018125,018234","Immunology/Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Halcinonide(SQ-18566) is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent.",454.96,"3093-35-4",90,197.82,"<1",0,"http://selleckchem.com/products/halcinonide.html","C24H32ClFO5","free base","SQ-18566","CC1(C)OC2CC3C4CCC5=CC(=O)CCC5(C)C4(F)C(O)CC3(C)C2(O1)C(=O)CCl",2.384,4,1,2]
["S4099","Dexlansoprazole","f6","L1300-15","in 10mM DMSO","FDA,DMF,NDC",null,"202294","Gastroenterology","ATPase,Proton Pump","Transmembrane Transporters","Dexlansoprazole (T 168390, TAK 390,(R)-Lansoprazole), the dextrorotatory enantiomer of lansoprazole, is a proton pump inhibitor (PPI) formulated to have dual delayed-release properties. Dexlansoprazole selectively suppresses gastric acid secretion by direct inhibition of the H(+),K(+)-ATPase proton pump in the gastric parietal cell.",369.36,"138530-94-6",74,200.35,"<1",0,"http://selleckchem.com/products/dexlansoprazole.html","C16H14F3N3O2S","free base","T 168390, TAK 390,(R)-Lansoprazole","CC1=C(C[S](=O)C2=NC3=C([NH]2)C=CC=C3)N=CC=C1OCC(F)(F)F",3.442,4,1,6]
["S4100","Esmolol HCl","g6","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","076323,076474,076573,201126,205520,206608,207107,208538","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Esmolol (ASL8052) is a cardioselective b-blocker, used to control rapid heartbeats or abnormal heart rhythms.",331.83,"81161-17-3",66,198.9,66,198.9,"http://selleckchem.com/products/esmolol-hcl.html","C16H25NO4.HCl","Hydrochloride","ASL8052","Cl.COC(=O)CCC1=CC=C(OCC(O)CNC(C)C)C=C1",2.36,3,2,10]
["S4101","Voglibose","h6","L1300-15","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Endocrinology/Metabolic Disease","Carbohydrate Metabolism","Metabolism","Voglibose (AO 128) is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various disorders caused by hyperglycemia.",267.28,"83480-29-9",74,276.86,74,276.86,"http://selleckchem.com/products/voglibose.html","C10H21NO7","free base","AO 128","OCC(CO)NC1CC(O)(CO)C(O)C(O)C1O",-4.083,0,7,5]
["S4102","Eprosartan Mesylate","a7","L1300-15","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37","202012","Cardiovascular Disease","Angiotensin Receptor","GPCR & G Protein","Eprosartan(SKF-108566J) is a nonpeptide angiotensin II receptor antagonist, [3H]-eprosartan binds to the AT1 receptor with KD of 0.83 nM in rat vascular smooth muscle cells.",520.62,"144143-96-4",104,199.76,"<1",0,"http://selleckchem.com/products/eprosartan-mesylate.html","C23H24N2O4S.CH4O3S","Mesylate","SKF-108566J","CCCCC1=NC=C(\\C=C(CC2=CC=CS2)\\C(O)=O)[N]1CC3=CC=C(C=C3)C(O)=O.C[S](O)(=O)=O",4.418,3,0,10]
["S4104","Diminazene Aceturate","b7","L1300-15","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Parasite","ACE,Parasite","Microbiology","Diminazene(Diminazene diaceturate) is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent.  The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties.",515.52,"908-54-3",19,36.86,100,193.98,"http://selleckchem.com/products/diminazene-aceturate.html","C14H15N7.2C4H7NO3","Aceturate","Diminazene diaceturate","CC(=O)NCC(O)=O.CC(=O)NCC(O)=O.NC(=N)C1=CC=C(NN=NC2=CC=C(C=C2)C(N)=N)C=C1",-0.592,6,5,9]
["S4105","Closantel Sodium","c7","L1300-15","in 10mM DMSO",null,"EP9.7;BP2019",null,"Parasite","Bacterial","Microbiology","Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.",685.06,"61438-64-0",100,145.97,"<1",0,"http://selleckchem.com/products/closantel-sodium.html","C22H13Cl2I2N2O2.Na","Sodium Salt","N/A","[Na+].CC1=C(NC(=O)C2=CC(=CC(=C2[O-])I)I)C=C(Cl)C(=C1)C(C#N)C3=CC=C(Cl)C=C3",6.049,1,1,4]
["S4106","Closantel","d7","L1300-15","in 10mM DMSO",null,"EP9.7;BP2019",null,"Parasite","Bacterial","Microbiology","Closantel (R-31520,nsc 335306) is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.",663.07,"57808-65-8",100,150.81,"<1",0,"http://selleckchem.com/products/closantel.html","C22H14Cl2I2N2O2","Free Base","R-31520,nsc 335306","CC1=C(NC(=O)C2=CC(=CC(=C2O)I)I)C=C(Cl)C(=C1)C(C#N)C3=CC=C(Cl)C=C3",6.752,1,2,4]
["S4107","Clofazimine","e7","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37, EP9.2,Ph.Int_6th,BP2017,IP2010","019500","Infection","Antineoplastic and Immunosuppressive Antibiotics,Dyes,Phospholipase (e.g. PLA)","Metabolism","Clofazimine (NSC-141046) is a rhimophenazine dye, originally developed for the treatment of tuberculosis, it has both antimicrobial and antiinflammatory activity, postulated mechanisms of action include intercalation of clofazimine with bacterial DNA and increasing levels of cellular phospholipase A2.",473.4,"2030-63-9",5,10.56,"<1",0,"http://selleckchem.com/products/clofazimine.html","C27H22Cl2N4","free base","NSC-141046","CC(C)N=C1C=C2N(C3=CC=C(Cl)C=C3)C4=C(C=CC=C4)N=C2C=C1NC5=CC=C(Cl)C=C5",7.137,2,1,4]
["S4110","Estradiol Benzoate","f7","L1300-15","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ，EP9.1,JP17,BP2017",null,"Cancer/Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estradiol benzoate(β-Estradiol 3-benzoate) is an estradiol analog which binds to the human, murine and chicken ERα with IC50 of 22-28 nM.",376.49,"50-50-0",75,199.21,"<1",0,"http://selleckchem.com/products/estradiol-benzoate.html","C25H28O3","free base","β-Estradiol 3-benzoate","CC12CCC3C(CCC4=CC(=CC=C34)OC(=O)C5=CC=CC=C5)C1CCC2O",5.512,2,1,3]
["S4111","Dicloxacillin Sodium","g7","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","061454,061455,062286","Infection","β-lactamase","Microbiology","Dicloxacillin Sodium (Veracillin, BRL1702) is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative aerobic and anaerobic bacteria.",510.32,"343-55-5",100,195.96,100,195.96,"http://selleckchem.com/products/dicloxacillin-sodium.html","C19H17Cl2N3O5S.H2O.Na","Sodium Salt","Veracillin, BRL1702","O.CC1=C(C(=O)NC2C3SC(C)(C)C(N3C2=O)C(=O)O[Na])C(=NO1)C4=C(Cl)C=CC=C4Cl",2.848,6,1,5]
["S4112","Desvenlafaxine Succinate hydrate","h7","L1300-15","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","204003,204020,204028,204065,204082,204083,204095,204172,204805,210014","Psychotic disorders","Adrenergic Receptor,Serotonin Transporter","Neuronal Signaling","Desvenlafaxine Succinate hydrate (WY 45233) is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively.",399.48,"386750-22-7",80,191.22,"<1",0,"http://selleckchem.com/products/desvenlafaxine-succinate.html","C16H25NO2.C4H6O4.H2O","Succinate hydrate","WY 45233  Succinate","O.CN(C)CC(C1=CC=C(O)C=C1)C2(O)CCCCC2.OC(=O)CCC(O)=O",-0.598,2,1,7]
["S4113","Desvenlafaxine","a8","L1300-15","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","204009,204150,205208,205583","Psychotic disorders","Adrenergic Receptor,Serotonin Transporter","Neuronal Signaling","Desvenlafaxine (WY 45233 Succinate) is a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with Ki of 40.2 nM and 558.4 nM, respectively.",263.38,"93413-62-8",37,140.48,"<1",0,"http://selleckchem.com/products/desvenlafaxine.html","C16H25NO2","Free Base","WY 45233  Succinate","CN(C)CC(C1=CC=C(O)C=C1)C2(O)CCCCC2",2.796,0,1,4]
["S4114","Triclabendazole","b8","L1300-15","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,BP2017","208711","Parasite","Microtubule Associated","Cytoskeletal Signaling","Triclabendazole (CGA-89317,tcbz) is a benzimidazole, it binds to tubulin impairing intracellular transport mechanisms and interferes with protein synthesis.",359.66,"68786-66-3",72,200.19,"<1",0,"http://selleckchem.com/products/triclabendazole.html","C14H9Cl3N2OS","free base","CGA-89317,tcbz","CSC1=NC2=C([NH]1)C=C(Cl)C(=C2)OC3=C(Cl)C(=CC=C3)Cl",5.982,2,1,3]
["S4118","Histamine 2HCl","c8","L1300-15","in 10mM DMSO","FDA,EMA,HMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017,IP2010","000734","Immunology","Histamine Receptor","Neuronal Signaling","Histamine(Ceplene) is an organic nitrogen compound, acts on target cells in mammalian brain via stimulation of Histamine 1/2.",184.07,"56-92-8",3,16.3,37,201.01,"http://selleckchem.com/products/histamine-2hcl.html","C5H9N3.2HCl","Dihydrochloride","Ceplene","Cl.Cl.NCCC1=C[NH]C=N1",0.05,1,2,2]
["S4119","Pefloxacin Mesylate Dihydrate","d8","L1300-15","in 10mM DMSO","CFDA","CP2005",null,"Infection","Topoisomerase","DNA Damage/DNA Repair","Pefloxacin Mesylate Dihydrate (1589 RB,Pefloxacinium mesylate dihydrate) is the third generation of fluoroquinolone class of antibacterials, which inhibits Topoisomerase II activity and DNA replication.",465.49,"149676-40-4",9,19.33,67,143.93,"http://selleckchem.com/products/pefloxacin-mesylate-dihydrate.html","C17H20FN3O3.CH4O3S.2H2O","Mesylate","1589 RB,Pefloxacinium mesylate dihydrate","O.O.CCN1C=C(C(O)=O)C(=O)C2=C1C=C(N3CCN(C)CC3)C(=C2)F.C[S](O)(=O)=O",-2.033,2,0,3]
["S4120","Sulconazole Nitrate","e8","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","018737,018738","Infection","Fungal","Microbiology","Sulconazole Nitrate(Exelderm,RS 44872) is an imidazole derivative with broad-spectrum antifungal activity.",460.76,"61318-91-0",92,199.67,"<1",0,"http://selleckchem.com/products/sulconazole-nitrate.html","C18H15Cl3N2S.HNO3","Nitrate","Exelderm,RS 44872","O[N+]([O-])=O.ClC1=CC=C(CSC(C[N]2C=CN=C2)C3=CC=C(Cl)C=C3Cl)C=C1",4.467,1,0,6]
["S4122","Tilmicosin","f8","L1300-15","in 10mM DMSO",null,"USP42-NF37",null,"Infection","Antibiotics","Microbiology","Tilmicosin (EL 870,LY-177370) is a macrolide antibiotic.",869.13,"108050-54-0",100,115.06,8,9.2,"http://selleckchem.com/products/tilmicosin.html","C46H80N2O13","free base","EL 870,LY-177370","CCC1OC(=O)CC(O)C(C)C(OC2OC(C)C(O)C(C2O)N(C)C)C(CCN3CC(C)CC(C)C3)CC(C)C(=O)\\C=C\\C(=C\\C1COC4OC(C)C(O)C(OC)C4OC)C",3.86,9,4,12]
["S4123","Timolol Maleate","g8","L1300-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","020963,072001,072002,072003,072269,072270,072271,072466,072467,072468,072550,072551,072552,072648,072649,072650,072668,072917,072918,072919,074261,074262,074465,074466,074515,074516,074667,074668,074746,074747,074776,074778,075163,075411,075412,077259,078771,204912,204936,207556","Cardiovascular Disease/Neurological Disease","Adrenergic Receptor","Neuronal Signaling","Timolol Maleate (MK-950,(S)-Timolol Maleate) is a non-selective, beta-adrenergic receptor antagonist for β1/β2 with Ki of 1.97 nM/2.0 nM.",432.49,"26921-17-5",86,198.85,"<1",0,"http://selleckchem.com/products/timolol-maleate.html","C13H24N4O3S.C4H4O4","Maleate","MK-950,(S)-Timolol Maleate","CC(C)(C)NCC(O)COC1=NSN=C1N2CCOCC2.OC(=O)\\C=C/C(O)=O",-1.539,6,2,9]
["S4124","Tolazoline HCl","h8","L1300-15","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ","006403","Angiology","Adrenergic Receptor","Neuronal Signaling","Tolazoline(Imidaline hydrochloride,NSC35110 hydrochloride) is a non-selective competitive α-adrenergic receptor antagonist.",196.68,"59-97-2",39,198.29,39,198.29,"http://selleckchem.com/products/tolazoline-hcl.html","C10H12N2.HCl","Hydrochloride","Imidaline hydrochloride,NSC35110 hydrochloride","Cl.C1CN=C(CC2=CC=CC=C2)N1",1.533,1,1,2]
["S4125","Sodium Phenylbutyrate","a9","L1300-15","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017,USP39-NF34","090910,202819,203918,204395","Metabolic Disease","HDAC","DNA Damage/DNA Repair","Sodium phenylbutyrate (4-PBA, 4-Phenylbutyric acid, NaPB) is a salt of 4-phenylbutyrate (4-PBA) or 4-phenylbutyric acid.Sodium phenylbutyrate is a histone deacetylase inhibitor, used to treat urea cycle disorders.",187.19,"1716-12-7",8,42.97,30,161.13,"http://selleckchem.com/products/sodium-phenylbutyrate.html","C10H11O2.Na","Sodium Salt","4-PBA, 4-Phenylbutyric acid, NaPB","[Na]OC(=O)CCCC1=CC=CC=C1",2.497,2,0,5]
["S4128","Troxipide","b9","L1300-15","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Gastroenterology/Inflammation","Others","Others","Troxipide(KU 54) is a novel systemic non-antisecretory gastric cytoprotective agent with anti-ulcer, anti-inflammatory and mucus secreting properties irrespective of pH of stomach or duodenum.",294.35,"30751-05-4",18,61.15,"<1",0,"http://selleckchem.com/products/troxipide.html","C15H22N2O4","free base","KU 54","COC1=C(OC)C(=CC(=C1)C(=O)NC2CCCNC2)OC",1.081,4,2,5]
["S4131","Levodropropizine","c9","L1300-15","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.2,BP2017",null,"Respiratory Disease","Histamine Receptor","Neuronal Signaling","Levodropropizine((S)-(-)-Dropropizine,DF-526) possess anti-allergic and inhibits histamine receptor, reduces cough by interfering with stimulus activation of peripheral endings of sensory nerves and by modulation of neuropeptides involved in the cough reflex.",236.31,"99291-25-5",47,198.89,15,63.48,"http://selleckchem.com/products/levodropropizine.html","C13H20N2O2","free base","(S)-(-)-Dropropizine,DF-526","OCC(O)CN1CCN(CC1)C2=CC=CC=C2",0.899,0,2,4]
["S4135","Clorprenaline HCl","d9","L1300-15","in 10mM DMSO","CFDA",null,null,"Inflammation/Respiratory Disease","Adrenergic Receptor","GPCR & G Protein","Clorprenaline HCl (NSC 334693) is a β2-receptor agonist, it has a significant expansion of the bronchial effect.",250.16,"6933-90-0",50,199.87,50,199.87,"http://selleckchem.com/products/clorprenaline-hcl.html","C11H16ClNO.HCl","Hydrochloride","NSC 334693","Cl.CC(C)NCC(O)C1=CC=CC=C1Cl",2.629,0,2,4]
["S4136","Carprofen","e9","L1300-15","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017","018550","Inflammation/Neurological Disease","COX","Neuronal Signaling","Carprofen inhibits canine COX2 with IC50 of 30 nM.",273.71,"53716-49-7",55,200.94,"<1",0,"http://selleckchem.com/products/carprofen.html","C15H12ClNO2","free base","N/A","CC(C(O)=O)C1=CC2=C(C=C1)C3=C([NH]2)C=CC(=C3)Cl",4.114,1,1,2]
["S4138","Dropropizine","f9","L1300-15","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Respiratory Disease","Others","Others","Dropropizine (UCB-1967,(±)- Dropropizine) is a racemic non-opiate antitussive agent, it is used as a cough suppressant.",236.31,"17692-31-8",47,198.89,11,46.55,"http://selleckchem.com/products/dropropizine.html","C13H20N2O2","free base","UCB-1967,(±)- Dropropizine","OCC(O)CN1CCN(CC1)C2=CC=CC=C2",0.899,0,2,4]
["S4139","Cyclizine 2HCl","g9","L1300-15","in 10mM DMSO","FDA,CFDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","009495","Neurological Disease","Histamine Receptor","Neuronal Signaling","Cyclizine 2HCl is a piperazine derivative with Histamine H1 receptor antagonist activity.",339.3,"5897-18-7",7,20.63,68,200.41,"http://selleckchem.com/products/cyclizine-2hcl.html","C18H22N2.2HCl","Hydrochloride","N/A","Cl.Cl.CN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3",4.237,0,0,3]
["S4141","Dinitolmide","h9","L1300-15","in 10mM DMSO",null,"BP2017;Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","Parasite","Microbiology","Dinitolmide (Zoalene) is a broad-spectrum anticoccidial drug.",225.16,"148-01-6",45,199.86,"<1",0,"http://selleckchem.com/products/dinitolmide-zoalene.html","C8H7N3O5","free base","Zoalene","CC1=C(C=C(C=C1[N+]([O-])=O)[N+]([O-])=O)C(N)=O",1.107,1,1,3]
["S4143","Pentoxyverine Citrate","a10","L1300-15","in 10mM DMSO","CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17,BP2017",null,"Respiratory Disease","AChR","Neuronal Signaling","Pentoxyverine Citrate (Carbetapentane) is an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold.",525.59,"23142-01-0",100,190.26,100,190.26,"http://selleckchem.com/products/pentoxyverine-carbetapentane-citrate.html","C20H31NO3.C6H8O7","Citrate","Carbetapentane Citrate","CC(C)N(CCC(C(N)=O)(C1=CC=CC=C1)C2=CC=CC=N2)C(C)C.O[P](O)(O)=O",2.949,2,1,8]
["S4147","Azithromycin Dihydrate","b10","L1300-15","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia","050762","Infection/Parasitology","Anti-infection","Microbiology","Azithromycin Dihydrate(CP-62993 dihydrate) is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin.",785.02,"117772-70-0",100,127.39,10,12.74,"http://selleckchem.com/products/azithromycin-dihydrate.html","C38H72N2O12.2H2O","free base","CP-62993 dihydrate","O.O.CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)CN(C)C(C)C(O)C1(C)O",1.663,7,3,7]
["S4148","Ampicillin Trihydrate","c10","L1300-15","in 10mM DMSO","FDA,CFDA,DMF","Martindale:The Extra Pharmacopoeia,EP9.1,Ph.Int_6th,BP2017,IP2010","060765,061370,061387,061502,061601,061602,061755,061829,061853,061980,062208,062882,062883,062982,064082","Infection","Antibiotics,Antibiotics for Mammalian Cell Culture,Bacterial","Microbiology","Ampicillin Trihydrate (NCI-C56086,D-(-)-α-Aminobenzylpenicillin trihydrate) is a β-lactam antibiotic, which inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane.",403.45,"7177-48-2",81,200.77,2,4.96,"http://selleckchem.com/products/ampicillin-trihydrate.html","C16H19N3O4S.3H2O","free base","NCI-C56086,D-(-)-α-Aminobenzylpenicillin trihydrate","O.O.O.CC1(C)SC2C(NC(=O)C(N)C3=CC=CC=C3)C(=O)N2C1C(O)=O",-2.919,3,2,4]
["S4149","Amfenac Sodium Monohydrate","d10","L1300-15","in 10mM DMSO","PMDA",null,null,"Inflammation","COX","Neuronal Signaling","Amfenac Sodium monohydrate is a non-steroidal analgesic anti-inflammatory drug with acetic acid moiety. The IC50 values for COX1 and COX2 is 250 nM and 150 nM, respectively.",295.27,"61618-27-7",59,199.82,59,199.82,"http://selleckchem.com/products/amfenac-sodium-monohydrate.html","C15H12NO3.H2O.Na","free base","N/A","O.[Na+].NC1=C(C=CC=C1CC([O-])=O)C(=O)C2=CC=CC=C2",0.47,1,1,4]
["S4151","Penfluridol","e10","L1300-15","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Penfluridol (TLP-607,R-16341) is a highly potent, first generation diphenylbutylpiperidine antipsychotic.",523.97,"26864-56-2",100,190.85,"<1",0,"http://selleckchem.com/products/penfluridol.html","C28H27ClF5NO","free base","TLP-607,R-16341","OC1(CCN(CCCC(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3)CC1)C4=CC(=C(Cl)C=C4)C(F)(F)F",7.311,0,0,8]
["S4152","Ethamsylate","f10","L1300-15","in 10mM DMSO","CFDA",null,null,"Angiology","Prostaglandin Receptor","GPCR & G Protein","Ethamsylate (Etamsylate) is a haemostatic drug, which inhibits biosynthesis and action of prostaglandins, and increases capillary endothelial resistance as and platelet adhesion.",263.31,"2624-44-4",53,201.28,53,201.28,"http://selleckchem.com/products/ethamsylate.html","C6H6O5S.C4H11N","Diethylamine","Etamsylate","CCNCC.OC1=CC=C(O)C(=C1)[S](O)(=O)=O",1.16,0,3,3]
["S4155","Chlorzoxazone","g10","L1300-15","in 10mM DMSO","DMF,CFDA,NDC,FDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ","040113,040137,040861,081019,081040,081298,081299,086901,086948,087981,088928,089592,089852,089853,089859,089895,089948,089970,207483","Neurological Disease","P450 (e.g. CYP17)","Metabolism","Chlorzoxazone(Chlorzoxazon,Paraflex) is a muscle-relaxing drug,and a probe for human liver cytochrome P-450IIE1.",169.57,"95-25-0",34,200.51,"<1",0,"http://selleckchem.com/products/chlorzoxazone.html","C7H4ClNO2","free base","Chlorzoxazon,Paraflex","ClC1=CC2=C(OC(=O)N2)C=C1",2.004,2,1,0]
["S4159","Bezafibrate","h10","L1300-15","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.2,JP17,BP2017",null,"Cardiovascular Disease","PPAR","Metabolism","Bezafibrate (BM 15075) is the first clinically tested dual and pan-PPAR co-agonism.",361.82,"41859-67-0",72,198.99,"<1",0,"http://selleckchem.com/products/bezafibrate.html","C19H20ClNO4","free base","BM 15075","CC(C)(OC1=CC=C(CCNC(=O)C2=CC=C(Cl)C=C2)C=C1)C(O)=O",3.868,3,1,7]
["S4160","Penicillin G Sodium","a11","L1300-15","in 10mM DMSO","DMF,NDC,FDA","KP Ⅹ,EP9.0,IP2010","061046,061051,061935,063014,065068","Infection","Antibiotics,Antibiotics for Mammalian Cell Culture,Antibiotics for Plant Cell Culture","Microbiology","Penicillin G Sodium (Benzylpenicillin) is a β-lactam antibiotic produced by Penicillin spp.",356.37,"69-57-8",71,199.23,71,199.23,"http://selleckchem.com/products/benzylpenicillin-sodium.html","C16H18N2O4S.Na","Sodium Salt","Benzylpenicillin Sodium","[Na+].CC1(C)SC2C(NC(=O)CC3=CC=CC=C3)C(=O)N2C1C([O-])=O",-0.35,2,1,4]
["S4161","Benzoic Acid","b11","L1300-15","in 10mM DMSO","DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,CP2005,EP7.0,Ph.Int_6th,JP17,BP2017,USP39-NF34,IP2010",null,"Infection","Others","Microbiology","Benzoic acid (FEMA 2131) is a colorless crystalline solid and a simple aromatic carboxylic acid, used as a food preservative.",122.12,"65-85-0",24,196.53,"<1",0,"http://selleckchem.com/products/benzoic-acid.html","C7H6O2","free base","FEMA 2131","OC(=O)C1=CC=CC=C1",1.459,1,0,1]
["S4162","Benzethonium Chloride","c11","L1300-15","in 10mM DMSO","NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,IP2010",null,"Others","AChR","Neuronal Signaling","Benzethonium chloride is a potent inhibitor of nAChRs, it inhibits α4β2 nAChRs and α7 nAChRs with IC50 of 49 nM and 122 nM, respectively.",448.08,"121-54-0",90,200.86,90,200.86,"http://selleckchem.com/products/benzethonium-chloride.html","C27H42NO2.Cl","Chloride","N/A","[Cl-].CC(C)(C)CC(C)(C)C1=CC=C(OCCOCC[N+](C)(C)CC2=CC=CC=C2)C=C1",2.147,2,0,12]
["S4163","Doxycycline Hyclate (WC2031)","d11","L1300-15","in 10mM DMSO","DMF,CFDA,NDC,FDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,BP2017,IP2010","061717,062031,062119,062142,062269,062337,062391,062392,062396,062418,062421,062432,062434,062442,062462,062463,062469,062479,062494,062500,062505,062538,062593,062594,062631,062643,062676,062677,062763,062764,062992,063187,065095,065103,065134,065163,065182,065277,065281,065287,090134,090431,090505,091052,200856,206772,207289,207494,207558,207773,207774,208765,208818,209243,209372,209969,210527,211012","Infection/Parasitology","Antineoplastic and Immunosuppressive Antibiotics,MMP","Proteases","Doxycycline Hyclate (WC2031, Doxycycline hydrochloride hemiethanolate hemihydrate) is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. It is also an inhibitor of matrix metallo-proteinases (MMP).",512.94,"24390-14-5",100,194.95,100,194.95,"http://selleckchem.com/products/doxycycline-hyclate.html","C22H24N2O8.1/2C2H6O.HCl.1/2H2O","hyclate","Doxycycline hydrochloride hemiethanolate hemihydrate","O.Cl.Cl.CCO.CC1C2C(O)C3C(N(C)C)C(=C(C(N)=O)C(=O)C3(O)C(=C2C(=O)C4=C(O)C=CC=C14)O)O.CC5C6C(O)C7C(N(C)C)C(=C(C(N)=O)C(=O)C7(O)C(=C6C(=O)C8=C(O)C=CC=C58)O)O",-0.955,6,11,4]
["S4164","Doxofylline","e11","L1300-15","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,IP2010",null,"Immunology/Inflammation/Psychotic disorders","PDE","Metabolism","Doxofylline (Doxophylline) is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma.",266.25,"69975-86-6",53,199.06,24,90.14,"http://selleckchem.com/products/doxofylline.html","C11H14N4O4","free base","Doxophylline","CN1C(=O)N(C)C2=C([N](CC3OCCO3)C=N2)C1=O",-0.344,5,0,2]
["S4165","Benzydamine HCl","f11","L1300-15","in 10mM DMSO","CFDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,BP2017",null,"Inflammation/Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Benzydamine HCl (AF864) is a topical nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, antipyretic and local anesthetic activity.",345.87,"132-69-4",69,199.5,69,199.5,"http://selleckchem.com/products/benzydamine-hcl.html","C19H23N3O.HCl","Hydrochloride","AF864","Cl.CN(C)CCCOC1=N[N](CC2=CC=CC=C2)C3=CC=CC=C13",4.368,2,0,7]
["S4166","Chlorpropamide","g11","L1300-15","in 10mM DMSO","DMF,CFDA,NDC,FDA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017,IP2010","084669,086865,086866,087353,088175,088176,088549,088568,088608,088662,088694,088695,088708,088709,088725,088726,088768,088812,088813,088826,088840,088852,088918,088919,088921,088922,089321,089446,089447,089561,089562","Endocrinology/Metabolic Disease","ATPase","Transmembrane Transporters","Chlorpropamide inhibits Na(+),K(+)-ATPase and stimulates a high affinity cyclic AMP-phosphodiesterase of isolated liver plasma membrane. Chlorpropamide is a sulfonylurea class drug for type 2 diabetes mellitus.",276.74,"94-20-2",55,198.74,"<1",0,"http://selleckchem.com/products/chlorpropamide.html","C10H13ClN2O3S","free base","N/A","CCCNC(=O)N[S](=O)(=O)C1=CC=C(Cl)C=C1",2.058,3,2,4]
["S4167","Cyromazine","h11","L1300-15","in 10mM DMSO",null,"USP42-NF37;Martindale:The Extra Pharmacopoeia",null,"Others","Parasite","Microbiology","Cyromazine(Cyromazin,CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide.",166.18,"66215-27-8",33,198.58,1,6.02,"http://selleckchem.com/products/cyromazine.html","C6H10N6","free base","Cyromazin,CGA-72662","NC1=NC(=NC(=N1)N)NC2CC2",0.313,3,3,2]
["S4169","Teriflunomide","a2","L1300-16","in 10mM DMSO","DMF,EMA,NDC,FDA",null,"209549,209555,209572,209601,209613,209623,209638,209663,209668,209690,209697,209700,209710","Neurological Disease","Dehydrogenase,Immunology & Inflammation related","Metabolism","Teriflunomide (A77 1726, HMR-1726) is the active metabolite of leflunomide, inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase, used as an immunomodulatory agent.",270.21,"163451-81-8",32,118.43,"<1",0,"http://selleckchem.com/products/teriflunomide.html","C12H9F3N2O2","free base","A77 1726, HMR-1726","C/C(O)=C(C#N)/C(=O)NC1=CC=C(C=C1)C(F)(F)F",2.091,1,2,3]
["S4170","Coumarin","b2","L1300-16","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia,EP7.0,BP2017",null,"Hematology","Immunology & Inflammation related","Immunology & Inflammation","Coumarin is a secondary phytochemical with hepatotoxic and carcinogenic properties.",146.14,"91-64-5",29,198.44,"<1",0,"http://selleckchem.com/products/coumarin.html","C9H6O2","free base","N/A","O=C1OC2=C(C=CC=C2)C=C1",1.899,2,0,0]
["S4171","Choline Chloride","c2","L1300-16","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010",null,"Nutritional support","AChR","Neuronal Signaling","Choline chloride(Hepacholine) is a quaternary ammonium salt used as an additive for animal feed. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.",139.62,"67-48-1",28,200.54,28,200.54,"http://selleckchem.com/products/choline-chloride.html","C5H14NO.Cl","Chloride","Hepacholine","[Cl-].C[N+](C)(C)CCO",-4.248,0,1,2]
["S4172","Cetylpyridinium Chloride","d2","L1300-16","in 10mM DMSO","DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017",null,"Others","Anti-infection","Microbiology","Cetylpyridinium chloride(CPC) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.",339.99,"123-03-5",68,200.01,68,200.01,"http://selleckchem.com/products/cetylpyridinium-chloride.html","C21H38N.Cl","Chloride","CPC","[Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1",5.563,0,0,15]
["S4173","1-Hexadecanol","e2","L1300-16","in 10mM DMSO","DMF",null,null,"Others","Others","Others","1-Hexadecanol is a fatty alcohol used to make other chemicals.",242.44,"36653-82-4",68,280.48,68,280.48,"http://selleckchem.com/products/1-hexadecanol.html","C16H34O","free base","N/A","CCCCCCCCCCCCCCCCO",6.445,0,1,14]
["S4175","Sulfaguanidine","f2","L1300-16","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017",null,"Infection","Anti-infection","Microbiology","Sulfaguanidine is a sulfonamide used as an anti-infective agent.",214.24,"57-67-0",43,200.71,"<1",0,"http://selleckchem.com/products/sulfaguanidine.html","C7H10N4O2S","free base","N/A","NC(=N)N[S](=O)(=O)C1=CC=C(N)C=C1",-0.377,2,3,3]
["S4176","Trometamol","g2","L1300-16","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017,IP2010",null,"Metabolic Disease","COX","Neuronal Signaling","Trometamol(Tromethamine) is a proton acceptor used to treat acidemia.",121.14,"77-86-1",2,16.51,24,198.12,"http://selleckchem.com/products/trometamol.html","C4H11NO3","free base","Tromethamine","NC(CO)(CO)CO",-2.381,0,4,3]
["S4177","Uracil","h2","L1300-16","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia,EP9.1,BP2017,USP36-NF31",null,"Others","Others","Others","Uracil is one of the four nucleobases in the nucleic acid of RNA can be used for drug delivery and as a pharmaceutical.",112.09,"66-22-8",22,196.27,"<1",0,"http://selleckchem.com/products/uracil.html","C4H4N2O2","free base","N/A","O=C1NC=CC(=O)N1",-1.012,2,2,0]
["S4178","Climbazole","a3","L1300-16","in 10mM DMSO",null,"USP32-NF27;Martindale:The Extra Pharmacopoeia",null,"Infection","Fungal","Microbiology","Climbazole(BAY-e 6975) is a broad-spectrum imidazole antifungal agent that can provide anti-dandruff benefits.",292.76,"38083-17-9",59,201.53,"<1",0,"http://selleckchem.com/products/climbazole.html","C15H17ClN2O2","free base","BAY-e 6975","CC(C)(C)C(=O)C(OC1=CC=C(Cl)C=C1)[N]2C=CN=C2",3.766,3,0,5]
["S4179","Mezlocillin Sodium","b3","L1300-16","in 10mM DMSO","FDA,CFDA","Martindale:The Extra Pharmacopoeia,USP39-NF34","050549,062333,062372,062697","Infection","Antibiotics,Bacterial","Microbiology","Mezlocillin sodium is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms.",561.56,"42057-22-7",100,178.08,100,178.08,"http://selleckchem.com/products/mezlocillin-sodium.html","C21H25N5O8S2.Na","Sodium Salt","N/A","[Na+].CC1(C)SC2C(NC(=O)C(NC(=O)N3CCN(C3=O)[S](C)(=O)=O)C4=CC=CC=C4)C(=O)N2C1C([O-])=O",-1.69,6,2,6]
["S4181","Nicardipine HCl","c3","L1300-16","in 10mM DMSO","FDA,MDF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,EP9.3,KP Ⅹ,JP17","022276,074439,074540,074642,074670,074928,078405,078714,090125,090534,090664,090671","Cardiovascular Disease","ADC Cytotoxin,Calcium Channel","Transmembrane Transporters","Nicardipine HCl (RS-69216,YC-93) is a dihydropyridine calcium-channel blocking agent used for the treatment of vascular disorders.",515.99,"54527-84-3",100,193.8,"<1",0,"http://selleckchem.com/products/nicardipine-hcl.html","C26H29N3O6.HCl","Hydrochloride","RS-69216,YC-93","Cl.COC(=O)C1=C(C)NC(=C(C1C2=CC(=CC=C2)[N+]([O-])=O)C(=O)OCCN(C)CC3=CC=CC=C3)C",3.87,4,1,11]
["S4182","Nifuroxazide","d3","L1300-16","in 10mM DMSO",null,"BP2019;KP Ⅹ;EP9.2",null,"Gastroenterology/Inflammation","STAT","JAK/STAT","Nifuroxazide is a cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcription activity with IC50 of 3 μM against IL-6-induced STAT3 activation in U3A cells.",275.22,"965-52-6",55,199.84,"<1",0,"http://selleckchem.com/products/nifuroxazide.html","C12H9N3O5","free base","N/A","OC1=CC=C(C=C1)C(=O)N/N=C/C2=CC=C(O2)[N+]([O-])=O",1.855,3,2,4]
["S4184","Penciclovir","e3","L1300-16","in 10mM DMSO","FDA,CFDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia","020629","Infection","Antiviral","Microbiology","Penciclovir (BRL-39123, VSA 671,NSC-759624) is a purine acyclic nucleoside analogue with potent antiviral activity.",253.26,"39809-25-1",34,134.25,1,3.95,"http://selleckchem.com/products/penciclovir.html","C10H15N5O3","free base","BRL-39123, VSA 671,NSC-759624","NC1=NC(=O)C2=C(N1)[N](CCC(CO)CO)C=N2",-1.533,3,4,5]
["S4185","Tiratricol","f3","L1300-16","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","THR","Metabolism","Tiratricol (also known as TRIAC or triiodothyroacetic acid) is a thyroid hormone analogue.",621.93,"51-24-1",100,160.79,"<1",0,"http://selleckchem.com/products/tiratricol.html","C14H9I3O4","free base","triiodothyroacetic acid","OC(=O)CC1=CC(=C(OC2=CC=C(O)C(=C2)I)C(=C1)I)I",4.547,2,1,4]
["S4186","Domiphen Bromide","g3","L1300-16","in 10mM DMSO","DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,BP2017,IP2010",null,"Infection","Potassium Channel","Transmembrane Transporters","Domiphen bromide (NSC-39415) is a quaternary ammonium antiseptic with actions as a cationic surfactant.",414.46,"538-71-6",83,200.26,83,200.26,"http://selleckchem.com/products/domiphen-bromide.html","C22H40NO.Br","free base","NSC-39415","[Br-].CCCCCCCCCCCC[N+](C)(C)CCOC1=CC=CC=C1",3.157,1,0,15]
["S4187","Salicylanilide","h3","L1300-16","in 10mM DMSO","DMF,CFDA",null,null,"Infection","Fungal,Integrase,Reverse Transcriptase","Microbiology","Salicylanilides (WR10019,2-Hydroxybenzanilide) are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities.",213.23,"87-17-2",43,201.66,"<1",0,"http://selleckchem.com/products/salicylanilide.html","C13H11NO2","free base","WR10019,2-Hydroxybenzanilide","OC1=CC=CC=C1C(=O)NC2=CC=CC=C2",2.372,1,2,2]
["S4188","Sasapyrine","a4","L1300-16","in 10mM DMSO","DMF,CFDA,NDC",null,null,"Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Sasapyrine (Salsalate, NSC-49171) is a nonsteroidal oral anti-inflammatory agent.",258.23,"552-94-3",52,201.37,"<1",0,"http://selleckchem.com/products/sasapyrine.html","C14H10O5","free base","NSC-49171,Salsalate","OC(=O)C1=CC=CC=C1OC(=O)C2=CC=CC=C2O",2.649,3,1,4]
["S4189","Cyclandelate","b4","L1300-16","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37",null,"Angiology","Acyltransferase,Transferase","Metabolism","Cyclandelate (BS 572,3,5,5-Trimethylcyclohexyl mandelate) is an effective inhibitor of rat hepatic acycloenzyme A: cholesterol acyltransferase (ACAT) with IC50 of 80 μM.",276.37,"456-59-7",55,199.01,"<1",0,"http://selleckchem.com/products/cyclandelate.html","C17H24O3","free base","BS 572,3,5,5-Trimethylcyclohexyl mandelate","CC1CC(CC(C)(C)C1)OC(=O)C(O)C2=CC=CC=C2",3.636,2,1,4]
["S4190","Cinchophen","c4","L1300-16","in 10mM DMSO","CFDA",null,null,"Gastroenterology","Others","Others","Cinchophen(Cinconal) is an analgesic drug that is frequently used to treat gout.",249.26,"132-60-5",50,200.59,"<1",0,"http://selleckchem.com/products/cinchophen.html","C16H11NO2","free base","Cinconal","OC(=O)C1=C2C=CC=CC2=NC(=C1)C3=CC=CC=C3",3.593,2,0,2]
["S4191","Betamipron","d4","L1300-16","in 10mM DMSO",null,"JP17;Martindale:The Extra Pharmacopoeia",null,"Infection","Anti-infection","Microbiology","Betamipron (CS-443,N-Benzoyl-β-alanine) is a chemical compound which is used together with panipenem to inhibit panipenem uptake into the renal tubule and prevent nephrotoxicity.",193.2,"3440-28-6",39,201.86,"<1",0,"http://selleckchem.com/products/betamipron.html","C10H11NO3","free base","CS-443,N-Benzoyl-β-alanine","OC(=O)CCNC(=O)C1=CC=CC=C1",0.767,2,1,4]
["S4192","Chlorquinaldol","e4","L1300-16","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Infection","Anti-infection","Microbiology","Chlorquinaldol(Chloquinan) is an antimicrobial agent used for local antisepsy.",228.07,"72-80-0",46,201.69,"<1",0,"http://selleckchem.com/products/chlorquinaldol.html","C10H7Cl2NO","free base","Chloquinan","CC1=CC=C2C(=CC(=C(O)C2=N1)Cl)Cl",3.385,1,1,0]
["S4195","Broxyquinoline","f4","L1300-16","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Parasite","Anti-infection","Microbiology","Broxyquinoline(Dibromohydroxyquinoline) is an antiprotozoal agent and able to release oxygen free radicals from the water in mucous membranes.",302.95,"521-74-4",17,56.11,"<1",0,"http://selleckchem.com/products/broxyquinoline.html","C9H5Br2NO","free base","Dibromohydroxyquinoline","OC1=C2N=CC=CC2=C(Br)C=C1Br",3.271,1,1,0]
["S4196","Ethacridine lactate monohydrate","g4","L1300-16","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017",null,"Infection","Anti-infection","Microbiology","Ethacridine lactate monohydrate(Acrinol monohydrat) is an aromatic organic compound based on acridine used as an antiseptic agent.",361.39,"6402-23-9",72,199.23,5,13.84,"http://selleckchem.com/products/ethacridine-lactate-monohydrate.html","C15H15N3O.C3H6O3.H2O","Lactate","Acrinol monohydrat","O.CCOC1=CC2=C(N)C3=CC=C(N)C=C3N=C2C=C1.CC(O)C(O)=O",1.592,3,3,3]
["S4197","Bemegride","h4","L1300-16","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","GABA Receptor","Neuronal Signaling","Bemegride(Bemegrid,3-Ethyl-3-methylglutarimide) is a central nervous system stimulant and antidote for barbiturate poisoning.",155.19,"64-65-3",31,199.76,"<1",0,"http://selleckchem.com/products/bemegride.html","C8H13NO2","free base","Bemegrid,3-Ethyl-3-methylglutarimide","CCC1(C)CC(=O)NC(=O)C1",0.578,2,1,1]
["S4200","Tolperisone HCl","a5","L1300-16","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Neurological Disease","Sodium Channel","Transmembrane Transporters","Tolperisone HCl is an ion channel blocker and centrally-acting muscle relaxant.",281.82,"3644-61-9",56,198.71,56,198.71,"http://selleckchem.com/products/tolperisone-hcl.html","C16H23NO.HCl","Hydrochloride","N/A","Cl.CC(CN1CCCCC1)C(=O)C2=CC=C(C)C=C2",4.072,1,0,4]
["S4201","Florfenicol","b5","L1300-16","in 10mM DMSO","EMA","Martindale:The Extra Pharmacopoeia",null,"Infection","Bacterial","Microbiology","Florfenicol (SCH-25298,(-)-Florfenicol) is a fluorinated synthetic analog of thiamphenicol with broad-spectrum, primarily bacteriostatic activity.",358.21,"73231-34-2",72,201,"<1",0,"http://selleckchem.com/products/florfenicol.html","C12H14Cl2FNO4S","free base","SCH-25298,(-)-Florfenicol","C[S](=O)(=O)C1=CC=C(C=C1)C(O)C(CF)NC(=O)C(Cl)Cl",1.597,3,2,6]
["S4202","Verapamil (CP-16533-1) HCl","c5","L1300-16","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","070672","Angiology/Cardiovascular Disease/Neurological Disease","Calcium Channel,P450 (e.g. CYP17),P-gp","Transmembrane Transporters","Verapamil HCl (CP-16533-1,(±)-Verapamil hydrochloride) is an L-type calcium channel blocker that is a class IV anti-arrhythmia agent. Verapamil inhibits both permeability-glycoprotein (P-gp) and CYP3A4.",491.06,"152-11-4",98,199.57,50,101.82,"http://selleckchem.com/products/verapami-hcl.html","C27H38N2O4.HCl","Hydrochloride","(±)-Verapamil hydrochloride","Cl.COC1=CC=C(CCN(C)CCCC(C#N)(C(C)C)C2=CC=C(OC)C(=C2)OC)C=C1OC",5.916,4,0,13]
["S4203","Furaltadone HCl","d5","L1300-16","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Infection","Bacterial","Microbiology","Furaltadone HCl(Altafur hydrochloride) is an antibacterial and has distinct curative effect in the treatment of coccidiosis.",360.75,"3759-92-0",17,47.12,72,199.58,"http://selleckchem.com/products/furaltadone-hcl.html","C13H16N4O6.HCl","Hydrochloride","Altafur hydrochloride","Cl.[O-][N+](=O)C1=CC=C(O1)/C=N/N2CC(CN3CCOCC3)OC2=O",1.337,5,0,5]
["S4204","Isosorbide","e5","L1300-16","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17","017063","Angiology/Cardiovascular Disease","Others","Others","Isosorbide(D-Isosorbide,Dianhydro-D-glucitol) is a heterocyclic compound that is derived from glucose, used as a diuretic.",146.14,"652-67-5",29,198.44,29,198.44,"http://selleckchem.com/products/isosorbide.html","C6H10O4","free base","D-Isosorbide,Dianhydro-D-glucitol","OC1COC2C(O)COC12",-1.408,2,2,0]
["S4206","Cysteamine HCl","f5","L1300-16","in 10mM DMSO","FDA,DMF,NDC,PMDA",null,"200740","Metabolic Disease","Antioxidant","Metabolism","Cysteamine HCl(Mercaptamine) is an autophagy-stimulatory proteostasis regulator. Cysteamine can be used for the treatment of nephropathic cystinosis and an antioxidant.",113.61,"156-57-0",23,202.45,23,202.45,"http://selleckchem.com/products/cysteamine-hcl.html","C2H7NS.HCl","Hydrochloride","Mercaptamine","Cl.NCCS",0.166,0,1,1]
["S4207","Clofibric Acid","g5","L1300-16","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","PPAR","Metabolism","Clofibric acid(Chlorofibrinic acid) is a PPARα agonist and hypolipidemic agent.",214.65,"882-09-7",43,200.33,"<1",0,"http://selleckchem.com/products/clofibric-acid.html","C10H11ClO3","free base","Chlorofibrinic acid","CC(C)(OC1=CC=C(Cl)C=C1)C(O)=O",2.755,2,0,3]
["S4208","Chromocarb","h5","L1300-16","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Angiology","Others","Others","Chromocarb(Atremon) is a vasoprotectant.",190.15,"4940-39-0",38,199.84,"<1",0,"http://selleckchem.com/products/chromocarb.html","C10H6O4","free base","Atremon","OC(=O)C1=CC(=O)C2=CC=CC=C2O1",1.247,3,0,1]
["S4210","Benzocaine","a6","L1300-16","in 10mM DMSO","DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,Ph.Int_6th,BP2017,IP2010",null,"Neurological Disease","Sodium Channel","Transmembrane Transporters","Benzocaine(ethyl 4-aminobenzoate) is the ethyl ester of p-aminobenzoic acid (PABA), it is a local anesthetic commonly used as a topical pain reliever or in cough drops.",165.19,"94-09-7",33,199.77,"<1",0,"http://selleckchem.com/products/benzocaine.html","C9H11NO2","Free Base","ethyl 4-aminobenzoate","CCOC(=O)C1=CC=C(N)C=C1",1.287,2,1,3]
["S4213","Dirithromycin","b6","L1300-16","in 10mM DMSO","FDA,CFDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,BP2017","050678","Infection","Antibiotics,Bacterial","Microbiology","Dirithromycin (LY-237216, ASE 136,Dynabac) is a macrolide glycopeptide antibiotic by binding to the 50S subunit of the 70S bacterial ribosome to inhibit the translocation of peptides.",835.07,"62013-04-1",11,13.17,"<1",0,"http://selleckchem.com/products/dirithromycin.html","C42H78N2O14","free base","LY-237216, ASE 136,Dynabac","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)C4NC(COCCOC)OC(C4C)C1(C)O",1.869,10,3,12]
["S4214","Sucralose","c6","L1300-16","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017,IP2010",null,"Others","Others","Others","Sucralose (E955,Trichloro Sucrose) is an artificial and noncaloric sweetener, not broken down by the body.",397.63,"56038-13-2",80,201.19,80,201.19,"http://selleckchem.com/products/sucralose.html","C12H19Cl3O8","free base","E955,Trichloro Sucrose","OCC1OC(OC2(CCl)OC(CCl)C(O)C2O)C(O)C(O)C1Cl",-0.697,3,5,5]
["S4216","Valnemulin HCl","d6","L1300-16","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Infection","Bacterial","Microbiology","Valnemulin HCl is a broad-spectrum bacteriostatic agent inhibiting protein synthesis in bacteria by binding to the peptidyl transferase component of the 50S subunit of ribosomes.",601.28,"133868-46-9",100,166.31,100,166.31,"http://selleckchem.com/products/valnemulin-hcl.html","C31H52N2O5S.HCl","Hydrochloride","N/A","Cl.CC(C)C(N)C(=O)NCC(C)(C)SCC(=O)OC1CC(C)(C=C)C(O)C(C)C23CCC(C)C1(C)C2C(=O)CC3",4.048,4,3,10]
["S4217","Liothyronine Sodium","e6","L1300-16","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,JP17,BP2016","076923,085753,085755,090097,090326,091382,200295,211510","Endocrinology","THR","Metabolism","Liothyronine Sodium(Cytomel) is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis.",672.96,"55-06-1",100,148.6,"<1",0,"http://selleckchem.com/products/liothyronine-sodium.html","C15H12I3NO4.Na","sodium","Cytomel","[Na+].NC(CC1=CC(=C(OC2=CC=C(O)C(=C2)I)C(=C1)I)I)C([O-])=O",2.452,1,2,5]
["S4219","Azaperone","f6","L1300-16","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017",null,"Neurological Disease","Dopamine Receptor","Neuronal Signaling","Azaperone (NSC 170976) crosses the blood-brain barrier and binds to both DI and D2 receptors, being an antagonist of Dopamine receptors with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.",327.4,"1649-18-9",65,198.53,"<1",0,"http://selleckchem.com/products/azaperone.html","C19H22FN3O","free base","NSC 170976","FC1=CC=C(C=C1)C(=O)CCCN2CCN(CC2)C3=CC=CC=N3",3.368,2,0,6]
["S4221","Benzbromarone","g6","L1300-16","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.2,JP17,BP2017",null,"Inflammation/Metabolic Disease","P450 (e.g. CYP17)","Metabolism","Benzbromarone(Desuric) is a CYP2C9 inhibitor, it binds to CYP2C9 with Ki value of 19.3 nM.",424.08,"3562-84-3",85,200.43,"<1",0,"http://selleckchem.com/products/benzbromarone.html","C17H12Br2O3","free base","Desuric","CCC1=C(C(=O)C2=CC(=C(O)C(=C2)Br)Br)C3=C(O1)C=CC=C3",5.604,2,1,3]
["S4222","Piperacillin Sodium","h6","L1300-16","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,JP17,BP2017","065114,065157,050545,062750","Infection","Antibiotics","Microbiology","Piperacillin (CL227193,Pipracil) is a semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections.",539.54,"59703-84-3",100,185.34,100,185.34,"http://selleckchem.com/products/piperacillin-sodium.html","C23H27N5O7S.Na","Sodium Salt","CL227193,Pipracil","[Na+].CCN1CCN(C(=O)NC(C(=O)NC2C3SC(C)(C)C(N3C2=O)C([O-])=O)C4=CC=CC=C4)C(=O)C1=O",-1.558,5,2,6]
["S4223","Mevastatin","a7","L1300-16","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","HMG-CoA Reductase","Metabolism","Mevastatin (ML-236B,Compactin) is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 times greater than the HMG-CoA substrate itself.",390.51,"73573-88-3",78,199.74,"<1",0,"http://selleckchem.com/products/mevastatin.html","C23H34O5","free base","ML-236B,Compactin","CCC(C)C(=O)OC1CCC=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C12",3.966,4,1,7]
["S4224","Erythritol","b7","L1300-16","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8,BP2017",null,"Angiology/Cardiovascular Disease","Others","Others","Erythritol(meso-Erythritol) is a sugar alcohol used as low-calorie sweetener.",122.12,"149-32-6",24,196.53,24,196.53,"http://selleckchem.com/products/erythritol.html","C4H10O4","free base","meso-Erythritol","OCC(O)C(O)CO",-1.919,0,4,3]
["S4225","Mexiletine HCl","c7","L1300-16","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,EMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,IP2010","074377,074450,074711,074865","Cardiovascular Disease","Sodium Channel","Transmembrane Transporters","Mexiletine HCl (KO1173,Mexitil) belongs to Class IB anti-arrhythmic group of medicines, inhibits sodium channels to reduce the inward sodium current.",215.72,"5370-01-4",43,199.33,43,199.33,"http://selleckchem.com/products/mexiletine-hcl.html","C11H17NO.HCl","Hydrochloride","KO1173,Mexitil","Cl.CC(N)COC1=C(C)C=CC=C1C",2.716,1,1,3]
["S4227","Fidaxomicin","d7","L1300-16","in 10mM DMSO","FDA,DMF,NDC,PMDA,EMA",null,"201699","Infection","DNA/RNA Synthesis","DNA Damage/DNA Repair","Fidaxomicin (OPT-80, PAR-101,Dificid) is a narrow spectrum macrocyclic antibiotic that inhibits RNA polymerase sigma subunit.",1058.04,"873857-62-6",100,94.51,"<1",0,"http://selleckchem.com/products/fidaxomicin.html","C52H74Cl2O18","free base","OPT-80, PAR-101,Dificid","CCC1\\C=C(C)/C(O)C\\C=C\\C=C(COC2OC(C)C(OC(=O)C3=C(CC)C(=C(O)C(=C3O)Cl)Cl)C(O)C2OC)\\C(=O)OC(C\\C=C(C)\\C=C(C)\\C1OC4OC(C)(C)C(OC(=O)C(C)C)C(O)C4O)C(C)O",7.774,11,7,15]
["S4228","Fluorometholone Acetate","e7","L1300-16","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","019079","Immunology/Infection/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Fluorometholone Acetate (NSC 47438,Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.",418.5,"3801-06-7",83,198.33,"<1",0,"http://selleckchem.com/products/fluorometholone-acetate.html","C24H31FO5","free base","NSC 47438,Oxylone acetate","CC1CC2C3CCC(OC(C)=O)(C(C)=O)C3(C)CC(O)C2(F)C4(C)C=CC(=O)C=C14",2.691,4,1,3]
["S4229","Oxybuprocaine HCl","f7","L1300-16","in 10mM DMSO","CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,JP17,BP2017",null,"Neurological Disease/Ophthalmology","Sodium Channel","Transmembrane Transporters","Oxybuprocaine HCl(oxybuprocaine hydrochloride) is a local anesthetic, which is used especially in ophthalmology and otolaryngology.  Oxybuprocaine binds to sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions",344.88,"5987-82-6",69,200.07,69,200.07,"http://selleckchem.com/products/oxybuprocaine-hcl.html","C17H28N2O3.HCl","Hydrochloride","oxybuprocaine hydrochloride","Cl.CCCCOC1=CC(=CC=C1N)C(=O)OCCN(CC)CC",3.469,3,1,11]
["S4230","Oxaprozin","g7","L1300-16","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,KP Ⅹ,JP17","075842,075843,075844,075845,075846,075847,075848,075849,075850,075851,075855,075987,208633","Immunology/Inflammation","COX","Metabolism","Oxaprozin (WY-21743,nsc 310839) is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID) used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis.",293.32,"21256-18-8",59,201.15,"<1",0,"http://selleckchem.com/products/oxaprozin.html","C18H15NO3","free base","WY-21743,nsc 310839","OC(=O)CCC1=NC(=C(O1)C2=CC=CC=C2)C3=CC=CC=C3",3.59,3,0,5]
["S4231","Pilocarpine HCl","h7","L1300-16","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17","076746,076963,077220,077248,204398","Ophthalmology","AChR","Neuronal Signaling","Pilocarpine HCl (NSC 5746) is a nonselective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy.",244.72,"54-71-7",48,196.14,48,196.14,"http://selleckchem.com/products/pilocarpine-hcl.html","C11H16N2O2.HCl","Hydrochloride","NSC 5746 HCl","Cl.CCC1C(COC1=O)CC2=CN=C[N]2C",1.347,3,0,3]
["S4235","Phenazopyridine HCl","a8","L1300-16","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","013294,019358,021105","Others","Sodium Channel","Transmembrane Transporters","Phenazopyridine HCl is a local analgesic that has been used in urinary tract disorders. It is an inhibitor of sodium channel protein type 1 subunit alpha.",249.7,"136-40-3",50,200.24,"<1",0,"http://selleckchem.com/products/phenazopyridine-hcl.html","C11H11N5.HCl","Hydrochloride","N/A","Cl.NC1=NC(=C(C=C1)N=NC2=CC=CC=C2)N",3.015,3,2,2]
["S4237","Primaquine Diphosphate","b8","L1300-16","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","EP9.6,Ph.Int_6th,BP2015","008316","Infection/Parasitology/Respiratory Disease","Anti-infection","Microbiology","Primaquine Diphosphate is a transmission-blocking anti-malarial clinically available, displaying a marked activity against gametocytes of all species of human malaria.",455.34,"63-45-6",91,199.85,91,199.85,"http://selleckchem.com/products/primaquine-diphosphate.html","C15H21N3O.2H3O4P","Diphosphate","N/A","COC1=CC(=C2N=CC=CC2=C1)NC(C)CCCN.O[P](O)(O)=O.O[P](O)(O)=O",1.062,2,2,6]
["S4238","Cepharanthine","c8","L1300-16","in 10mM DMSO","PMDA",null,null,"Cancer/Inflammation","TNF-alpha","Apoptosis","Cepharanthine (NSC-623442) is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production.",606.71,"481-49-2",100,164.82,"<1",0,"http://selleckchem.com/products/cepharanthine.html","C37H38N2O6","free base","NSC-623442","COC1=C2OC3=CC=C(CC4N(C)CCC5=C4C(=C6OCOC6=C5)OC7=C(OC)C=C8CCN(C)C(CC(=C2)C=C1)C8=C7)C=C3",7.019,6,0,2]
["S4239","Bergapten","d8","L1300-16","in 10mM DMSO",null,"BP2019;EP9.2",null,"Immunology/Inflammation","DNA/RNA Synthesis","DNA Damage/DNA Repair","Bergapten is a psoralen that can be photoactivated and is capable of crossing-linking DNA, covalently modifying proteins and lipids, and consequently inhibiting cell replication.",216.19,"484-20-8",5,23.13,"<1",0,"http://selleckchem.com/products/bergapten.html","C12H8O4","free base","N/A","COC1=C2C=COC2=CC3=C1C=CC(=O)O3",2.187,4,0,1]
["S4240","Doxylamine Succinate","e8","L1300-16","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017","040167,040564,088603,088900","Immunology/Neurological Disease","Histamine Receptor","Neuronal Signaling","Doxylamine succinate competitively inhibits histamine at H1 receptors with substantial sedative and anticholinergic effects.",388.46,"562-10-7",78,200.79,78,200.79,"http://selleckchem.com/products/doxylamine-succinate.html","C17H22N2O.C4H6O4","Succinate","N/A","CN(C)CCOC(C)(C1=CC=CC=C1)C2=CC=CC=N2.OC(=O)CCC(O)=O",-0.527,4,0,9]
["S4242","Cetrimonium Bromide (CTAB)","f8","L1300-16","in 10mM DMSO",null,"USP42-NF37;Martindale:The Extra Pharmacopoeia",null,"Immunology/Infection","Anti-infection","Microbiology","Cetrimonium Bromide (CTAB) is a known component of the broad-spectrum antiseptic cetrimide, which is a mixture of different quaternary ammonium salts.",364.45,"57-09-0",5,13.72,100,274.39,"http://selleckchem.com/products/cetrimonium-bromide.html","C19H42N.Br","free base","N/A","[Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C",3.35,0,0,15]
["S4243","Deoxycorticosterone acetate","g8","L1300-16","in 10mM DMSO","CFDA",null,null,"Endocrinology","Adrenergic Receptor","Neuronal Signaling","Deoxycorticosterone acetate (11-Deoxycorticosterone, DOC, Cortexone) is a steroid hormone used for intramuscular injection for replacement therapy of the adrenocortical steroid.",372.5,"56-47-3",11,29.53,"<1",0,"http://selleckchem.com/products/deoxycorticosterone-acetate.html","C23H32O4","free base","11-Deoxycorticosterone acetate, DOC acetate, Cortexone acetate","CC(=O)OCC(=O)C1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C",3.567,4,0,4]
["S4244","Serotonin HCl","h8","L1300-16","in 10mM DMSO","NDC","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease/Psychotic disorders","5-HT Receptor","Neuronal Signaling","Serotonin HCl (5-HT) is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist.",212.68,"153-98-0",42,197.48,42,197.48,"http://selleckchem.com/products/serotonin-hcl.html","C10H12N2O.HCl","Hydrochloride","5-HT HCl","Cl.NCCC1=C[NH]C2=CC=C(O)C=C12",1.69,0,3,2]
["S4246","Tranylcypromine (2-PCPA) HCl","a9","L1300-16","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017","040640,206856","Psychotic disorders","MAO","Metabolism","Tranylcypromine HCl (2-PCPA, SKF-385, Parnate) is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively.",169.65,"1986-47-6",33,194.52,33,194.52,"http://selleckchem.com/products/tranylcypromine-2-pcpa-hcl.html","C9H12ClN","Hydrochloride","SKF-385 HCl, Parnate,2-PCPA","Cl.NC1CC1C2=CC=CC=C2",2.309,0,1,1]
["S4247","Prucalopride Succinate","b9","L1300-16","in 10mM DMSO","FDA,CFDA,HMA",null,"210166","Cancer","5-HT Receptor","Neuronal Signaling","Prucalopride(R-108512) is a selective, high affinity 5-HT4 receptor agonist. The Ki values of prucalopride for human 5-HT(4a) and 5-HT(4b) receptor are 2.5 nM and 8 nM, respectively.",485.96,"179474-85-2",97,199.6,97,199.6,"http://selleckchem.com/products/prucalopride-succinat.html","C18H26ClN3O3.C4H6O4","Succinat","R-108512","COCCCN1CCC(CC1)NC(=O)C2=C3OCCC3=C(N)C(=C2)Cl.OC(=O)CCC(O)=O",-2.338,5,2,9]
["S4248","Bromfenac Sodium","c9","L1300-16","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","201211,201941,202030,202435,202620,203395,207584","Ophthalmology","COX","Neuronal Signaling","Bromfenac Sodium (AHR 10282R,Bromsite,Bromday,Prolensa,Xibrom) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.",356.15,"91714-93-1",71,199.35,71,199.35,"http://selleckchem.com/products/bromfenac-sodium.html","C15H11BrNO3.Na","Sodium Salt","AHR 10282R,Bromsite,Bromday,Prolensa,Xibrom","[Na+].NC1=C(C=CC=C1CC([O-])=O)C(=O)C2=CC=C(Br)C=C2",1.426,1,1,4]
["S4249","Flopropione","d9","L1300-16","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Neurological Disease","5-HT Receptor","Neuronal Signaling","Flopropione is a spasmolytic or antispasmodic agent, and acts as a 5-HT1A receptor antagonist.",182.17,"2295-58-1",36,197.62,"<1",0,"http://selleckchem.com/products/flopropione.html","C9H10O4","free base","N/A","CCC(=O)C1=C(O)C=C(O)C=C1O",1.51,1,3,2]
["S4250","Sulfamethoxypyridazine","e9","L1300-16","in 10mM DMSO",null,"EP9.2;Ph.Int_6th;Martindale:The Extra Pharmacopoeia",null,"Infection/Inflammation","Anti-infection","Microbiology","Sulfamethoxypyridazine (CL 13494) is a long-acting sulfonamide for treatment of Dermatitis herpetiformis.",280.3,"80-35-3",56,199.79,"<1",0,"http://selleckchem.com/products/sulfamethoxypyridazine.html","C11H12N4O3S","free base","CL 13494","COC1=NN=C(N[S](=O)(=O)C2=CC=C(N)C=C2)C=C1",1.014,5,2,4]
["S4253","Epinastine HCl","f9","L1300-16","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017","090870,090919,090950,090951,091626,203384,204055","Immunology/Inflammation","Histamine Receptor","Neuronal Signaling","Epinastine (WAL-801CL) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.",285.77,"108929-04-0",57,199.46,57,199.46,"http://selleckchem.com/products/epinastine-hcl.html","C16H15N3.HCl","Hydrochloride","WAL-801CL HCl","Cl.NC1=NCC2N1C3=CC=CC=C3CC4=CC=CC=C24",3.164,1,1,0]
["S4255","Quinacrine 2HCl","g9","L1300-16","in 10mM DMSO","DMF",null,null,"Infection/Parasitology","Phospholipase (e.g. PLA)","Metabolism","Quinacrine 2HCl(Quinacrine dihydrochloride) is a lipophilic cationic drug with multiple actions that is commonly used as an anti-protozoal agent. Quinacrine is an effective  phospholipase A2 inhibitor.",472.88,"69-05-6",14,29.61,53,112.08,"http://selleckchem.com/products/quinacrine-2hcl.html","C23H30ClN3O.2HCl","Dihydrochloride","Quinacrine dihydrochloride","Cl.Cl.CCN(CC)CCCC(C)NC1=C2C=C(OC)C=CC2=NC3=CC(=CC=C13)Cl",6.43,2,1,9]
["S4256","Buspirone HCl","h9","L1300-16","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,BP2017,IP2010","074253,075022,075119,075385,075388,075413,075467,075521,075572,076008,078246,078302,078888,202087,202330,202557,204582,208829,208972,209696","Psychotic disorders","5-HT Receptor","Neuronal Signaling","Buspirone(Buspirone hydrochloride) is a serotonergic (5HT(1A) receptor agonist) anxiolytic drug with some D(2) dopaminergic effect, used for anxiety disorders.",421.96,"33386-08-2",84,199.07,84,199.07,"http://selleckchem.com/products/buspirone-hcl.html","C21H31N5O2.HCl","Hydrochloride","Buspirone hydrochloride","Cl.O=C1CC2(CCCC2)CC(=O)N1CCCCN3CCN(CC3)C4=NC=CC=N4",2.403,4,0,6]
["S4257","Alizapride HCl","a10","L1300-16","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Gastroenterology","Dopamine Receptor","Neuronal Signaling","Alizapride HCl(Alizapride hydrochloride) is a dopamine receptor antagonist used for the theropy of nausea and vomiting.",351.83,"59338-87-3",42,119.38,70,198.96,"http://selleckchem.com/products/alizapride-hcl.html","C16H21N5O2.HCl","hydrochloride","Alizapride hydrochloride","Cl.COC1=CC2=C(C=C1C(=O)NCC3CCCN3CC=C)N=N[NH]2",2.253,4,2,6]
["S4258","Luliconazole","b10","L1300-16","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA",null,"204153","Infection","Fungal","Microbiology","Luliconazole(NND 502) is a broad-spectrum antifungal drug.",354.28,"187164-19-8",71,200.41,"<1",0,"http://selleckchem.com/products/luliconazole.html","C14H9Cl2N3S2","free base","NND 502","ClC1=CC=C(C2CSC(/S2)=C(C#N)\\[N]3C=CN=C3)C(=C1)Cl",4.031,1,0,2]
["S4259","Vilazodone HCl","c10","L1300-16","in 10mM DMSO","FDA,NDC,DMF",null,"208202,208209,208212","Psychotic disorders","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Vilazodone HCl(EMD68843,SB659746A) is a selective serotonin reuptake inhibitor (SSRI) and  a partial agonist of 5-HT1A receptors, used for the treatment of major depressive disorder.",477.99,"163521-08-2",96,200.84,"<1",0,"http://selleckchem.com/products/vilazodone-hcl.html","C26H27N5O2.HCl","Hydrochloride","EMD68843,SB659746A","Cl.NC(=O)C1=CC2=C(O1)C=CC(=C2)N3CCN(CCCCC4=C[NH]C5=C4C=C(C=C5)C#N)CC3",4.918,2,2,7]
["S4260","Tamibarotene","d10","L1300-16","in 10mM DMSO","DMF,PMDA","Martindale:The Extra Pharmacopoeia",null,"Cancer/Hematology","Retinoid Receptor","Metabolism","Tamibarotene(Am 80) is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ.",351.44,"94497-51-5",70,199.18,"<1",0,"http://selleckchem.com/products/tamibarotene.html","C22H25NO3","free base","Am 80","CC1(C)CCC(C)(C)C2=C1C=CC(=C2)NC(=O)C3=CC=C(C=C3)C(O)=O",4.673,2,1,3]
["S4263","Efaproxiral Sodium","e10","L1300-16","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease/Hematology","ROS","Immunology & Inflammation","Efaproxiral Sodium(RSR13 Sodium) is a synthetic allosteric modifier of hemoglobin, decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy. Efaproxiral Sodium is used for brain metastases originating from breast cancer.",363.38,"170787-99-2",73,200.89,73,200.89,"http://selleckchem.com/products/efaproxiral-sodium.html","C20H23NO4.Na","Sodium salt","RSR13 Sodium","[Na+].CC1=CC(=CC(=C1)NC(=O)CC2=CC=C(OC(C)(C)C([O-])=O)C=C2)C",2.408,2,1,6]
["S4264","Etofibrate","f10","L1300-16","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Angiology/Cardiovascular Disease","Others","Others","Etofibrate is a combination of clofibrate and niacin, used to treat hyperlipemia.",363.79,"31637-97-5",73,200.67,"<1",0,"http://selleckchem.com/products/etofibrate.html","C18H18ClNO5","free base","N/A","CC(C)(OC1=CC=C(Cl)C=C1)C(=O)OCCOC(=O)C2=CC=CN=C2",3.334,6,0,9]
["S4265","Nicaraven","g10","L1300-16","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Angiology","Others","Others","Nicaraven is a hydroxyl radical scavenger with antivasospastic and neuroprotective effects.",284.31,"79455-30-4",57,200.49,57,200.49,"http://selleckchem.com/products/nicaraven.html","C15H16N4O2","free base","N/A","CC(CNC(=O)C1=CN=CC=C1)NC(=O)C2=CN=CC=C2",-0.029,4,2,5]
["S4266","Brimonidine Tartrate","h10","L1300-16","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","076254,076260,076372,076439,078075,078479,078480,091691,203172,208992","Inflammation/Ophthalmology","Adrenergic Receptor","GPCR & G Protein","Brimonidine Tartrate(UK 1434 Tartrate) is a highly selective α-adrenergic receptor agonist with EC50 of 0.45 nM for the α2A adrenoreceptor, and used to treat open-angle glaucoma or ocular hypertension.",442.22,"70359-46-5",88,199,75,169.6,"http://selleckchem.com/products/brimonidine-tartrate.html","C15H16BrN5O6","Tartrate","UK 1434 Tartrate","OC(C(O)C(O)=O)C(O)=O.BrC1=C2N=CC=NC2=CC=C1NC3=NCCN3",-0.426,5,4,5]
["S4267","Diacerein","a11","L1300-16","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017,IP2010",null,"Inflammation","Interleukins","Immunology & Inflammation","Diacerein is an inhibitor of pro-inflammatory cytokine Interleukin-1B (IL-1B) production, prescribed for osteoarthritis and chronic inflammatory arthritis.",368.29,"13739-02-1",48,130.33,"<1",0,"http://selleckchem.com/products/diacerein.html","C19H12O8","free base","N/A","CC(=O)OC1=CC=CC2=C1C(=O)C3=C(C=C(C=C3OC(C)=O)C(O)=O)C2=O",1.973,7,0,5]
["S4268","Flufenamic acid","b11","L1300-16","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017",null,"Inflammation/Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Flufenamic Acid is an anti-inflammatory agent, and also acts as an ion channel modulator.",281.23,"530-78-9",56,199.13,"<1",0,"http://selleckchem.com/products/flufenamic-acid.html","C14H10F3NO2","free base","N/A","OC(=O)C1=CC=CC=C1NC2=CC=CC(=C2)C(F)(F)F",3.952,1,1,4]
["S4269","Vinorelbine ditartrate (KW-2307)","c11","L1300-16","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,EP9.4,KP Ⅹ,BP2017,IP2010","075992,076028,076461,076827,076849,078011,078408,091106,200148,202017","Cancer/Respiratory Disease","Apoptosis related,Autophagy,Microtubule Associated","Cytoskeletal Signaling","Vinorelbine Tartrate (KW-2307, Nor-5'-anhydrovinblastine ditartrate) is a semi-synthetic vinca alkaloid, and inhibits mitosis through interaction with tubulin. Vinorelbine Tartrate exhibits anti-tumor activities via inducing the mitotic apoptosis, autophagy and inflammation.",1079.11,"125317-39-7",100,92.67,100,92.67,"http://selleckchem.com/products/vinorelbine-tartrate.html","C45H54N4O8.2C4H6O6","ditartrate","Nor-5'-anhydrovinblastine ditartrate,KW-2307","CCC1=CC2CN(C1)CC3=C([NH]C4=C3C=CC=C4)C(C2)(C(=O)OC)C5=C(OC)C=C6N(C)C7C(O)(C(OC(C)=O)C8(CC)C=CCN9CCC7(C89)C6=C5)C(=O)OC.OC(C(O)C(O)=O)C(O)=O.OC(C(O)C(O)=O)C(O)=O",-4,11,5,16]
["S4270","Oxiracetam","d11","L1300-16","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","GABA Receptor","Neuronal Signaling","Oxiracetam (ISF 2522), a cyclic derivative of gamma-aminobutyric acid (GABA), is used as a nootropic drug to improve memory and learning.",158.16,"62613-82-5",31,196,31,196,"http://selleckchem.com/products/oxiracetam.html","C6H10N2O3","free base","ISF 2522","NC(=O)CN1CC(O)CC1=O",-2.143,2,2,2]
["S4274","Rotigotine","e11","L1300-16","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,EP9.6","021829","Neurological Disease","Dopamine Receptor","Neuronal Signaling","Rotigotine(N-0923) is a dopamine receptor agonist, used in the treatment of Parkinson's disease and restless legs syndrome.",315.47,"99755-59-6",63,199.7,"<1",0,"http://selleckchem.com/products/rotigotine.html","C19H25NOS","free base","N-0923","CCCN(CCC1=CC=CS1)C2CCC3=C(C2)C=CC=C3O",4.986,0,1,6]
["S4277","Bambuterol HCl","f11","L1300-16","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,BP2017",null,"Immunology/Respiratory Disease","Adrenergic Receptor","GPCR & G Protein","Bambuterol HCl(Bambuterol hydrochloride,KWD-2183 hydrochloride) is a potent β-adrenoceptor agonist, used in the treatment of asthma.",403.9,"81732-46-9",80,198.07,72,178.26,"http://selleckchem.com/products/bambuterol-hci.html","C18H29N3O5.HCl","Hydrochloride","Bambuterol hydrochloride,KWD-2183 hydrochloride","Cl.CN(C)C(=O)OC1=CC(=CC(=C1)OC(=O)N(C)C)C(O)CNC(C)(C)C",2.109,4,2,8]
["S4278","Carteolol HCl","g11","L1300-16","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","075476,075546,076097","Ophthalmology","Adrenergic Receptor","GPCR & G Protein","Carteolol HCl(Carteolol hydrochloride,OPC-1085 hydrochloride) is a β-adrenoceptor antagonist, used for the treatment of glaucoma.",328.83,"51781-21-6",65,197.67,65,197.67,"http://selleckchem.com/products/carteolol-hci.html","C16H25ClN2O3","Hydrochloride","Carteolol hydrochloride,OPC-1085 hydrochloride","Cl.CC(C)(C)NCC(O)COC1=C2CCC(=O)NC2=CC=C1",1.664,2,3,6]
["S4279","Demeclocycline HCl","h11","L1300-16","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","065094,065171,065389,065425,065447","Infection/Inflammation","Antibiotics,Bacterial","Microbiology","Demeclocycline HCl(Demeclocycline hydrochloride) is a tetracycline antibiotic via inhibition of protein synthesis by bacteria, used for the treatment of bacterial infections.",501.31,"64-73-3",100,199.48,26,51.86,"http://selleckchem.com/products/demeclocycline-hci.html","C21H21ClN2O8.HCl","Hydrochloride","Demeclocycline hydrochloride","Cl.CN(C)C1C2CC3C(O)C4=C(Cl)C=CC(=C4C(=O)C3=C(O)C2(O)C(=O)C(=C1O)C(N)=O)O",-0.053,3,5,2]
["S4280","Meclofenoxate (Centrophenoxine) HCl","a2","L1300-17","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Neurological Disease","Transferase","Metabolism","Meclofenoxate (Centrophenoxine) HCl is an anti-aging drug used to treat the symptoms of senile dementia and Alzheimer's disease, and also inhibits the activity of cholinephosphotransferase.",294.17,"3685-84-5",58,197.16,58,197.16,"http://selleckchem.com/products/meclofenoxate-centrophenoxine-hci.html","C12H17Cl2NO3","Hydrochloride","Centrophenoxine","Cl.CN(C)CCOC(=O)COC1=CC=C(Cl)C=C1",2.705,3,0,7]
["S4281","Tasimelteon","b2","L1300-17","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"205677","Neurological Disease","MT Receptor","Neuronal Signaling","Tasimelteon (BMS 214778, VEC 162) is a selective dual melatonin receptor (MT1/MT2) agonist with 2.1-4.4 times greater affinity for the MT2 receptor believed to mediate circadian rhythm phase-shifting (Ki = 0.0692 nM and Ki = 0.17 nM in NIH-3T3 and CHOeK1 cells, respectively), than for the MT1 receptor (Ki = 0.304 nM and Ki = 0.35 nM, respectively).",245.32,"609799-22-6",49,199.74,-1,-4.08,"https://www.selleckchem.com/products/tasimelteon.html","C15H19NO2","free base","BMS 214778, VEC 162","CCC(=O)NCC1CC1C2=C3CCOC3=CC=C2",2.203,2,1,4]
["S4282","Nelfinavir (AG 1343) Mesylate","c2","L1300-17","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,Ph.Int_6th","020778,020779,021503","Infection","COVID-19,HIV Protease","Proteases","Nelfinavir Mesylate (Viracept, AG1343) is a potent HIV protease inhibitor with Ki of 2 nM.",663.89,"159989-65-8",100,150.63,"<1",0,"http://selleckchem.com/products/nelfinavir-mesylate.html","C33H49N3O7S2","Mesylate","Viracept, AG1343","CC1=C(C=CC=C1O)C(=O)NC(CSC2=CC=CC=C2)C(O)CN3CC4CCCCC4CC3C(=O)NC(C)(C)C.C[S](O)(=O)=O",4.871,2,4,10]
["S4283","Cyclobenzaprine HCl","d2","L1300-17","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","071611,072854,073143,073144,073541,073683,074421,074436,077209,077563,077797,078048,078218,078643,078722,090478,090864,091281,206703,208170","Others","5-HT Receptor","Neuronal Signaling","Cyclobenzaprine HCl(Cyclobenzaprine hydrochloride) is a muscle relaxant by blocking pain sensations, used for the treatment of muscle spasms; A 5-HT2 receptor antagonist.",311.85,"6202-23-9",62,198.81,62,198.81,"http://selleckchem.com/products/cyclobenzaprine-hci.html","C20H22ClN","Hydrochloride","Cyclobenzaprine hydrochloride","Cl.CN(C)CCC=C1C2=C(C=CC=C2)C=CC3=C1C=CC=C3",4.709,0,0,3]
["S4284","Chloroprocaine HCl","e2","L1300-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","040273,087446,087447","Neurological Disease","Sodium Channel","Transmembrane Transporters","Chloroprocaine HCl is a local anesthetic during surgical procedures.",307.22,"3858-89-7",61,198.55,61,198.55,"http://selleckchem.com/products/chloroprocaine-hci.html","C13H20Cl2N2O2","Hydrochloride","N/A","Cl.CCN(CC)CCOC(=O)C1=C(Cl)C=C(N)C=C1",2.821,2,1,7]
["S4285","Ospemifene","f2","L1300-17","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"203505","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Ospemifene(FC-1271a) is a non-hormonal selective estrogen receptor modulator (SERM), used for the treatment of dyspareunia.",378.89,"128607-22-7",75,197.95,"<1",0,"http://selleckchem.com/products/ospemifene.html","C24H23ClO2","free base","FC-1271a","OCCOC1=CC=C(C=C1)\\C(=C(\\CCCl)C2=CC=CC=C2)C3=CC=CC=C3",5.62,1,1,8]
["S4286","Anidulafungin (LY303366)","g2","L1300-17","in 10mM DMSO","FDA,DMF,EMA,NDC,HMA","Martindale:The Extra Pharmacopoeia","021632,021948","Infection","Fungal","Microbiology","Anidulafungin (LY303366), an echinocandin derivative, inhibits glucan synthase activity, used as an antifungal drug.",1140.24,"166663-25-8",100,87.7,"<1",0,"http://selleckchem.com/products/anidulafungin-ly303366.html","C58H73N7O17","free base","LY303366","CCCCCOC1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)NC4CC(O)C(O)NC(=O)C5C(O)C(C)CN5C(=O)C(NC(=O)C(NC(=O)C6CC(O)CN6C(=O)C(NC4=O)C(C)O)C(O)C(O)C7=CC=C(O)C=C7)C(C)O",-0.358,8,14,14]
["S4288","Chloroambucil","h2","L1300-17","in 10mM DMSO","FDA,DMF,NDC",null,"010669","Cancer/Hematology","DNA/RNA Synthesis","DNA Damage/DNA Repair","Chloroambucil (Chlorambucil,CB-1348,WR-139013) is a nitrogen mustard alkylating agent, used in the treatment of chronic lymphocytic leukemia.",304.21,"305-03-3",60,197.23,"<1",0,"http://selleckchem.com/products/chloroambucil.html","C14H19Cl2NO2","free base","Chlorambucil,CB-1348,WR-139013","OC(=O)CCCC1=CC=C(C=C1)N(CCCl)CCCl",3.899,1,0,9]
["S4289","Metoclopramide HCl","a3","L1300-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,IP2010","070671","Gastroenterology","Dopamine Receptor","Neuronal Signaling","Metoclopramide HCl(Metoclopramide hydrochloride) is a selective dopamine D2 receptor antagonist, used for the treatment of nausea and vomiting.",336.26,"7232-21-5",67,199.25,67,199.25,"http://selleckchem.com/products/metoclopramide-hcl.html","C14H23Cl2N3O2","Hydrochloride","Metoclopramide hydrochloride","Cl.CCN(CC)CCNC(=O)C1=CC(=C(N)C=C1OC)Cl",2.157,2,2,7]
["S4291","Labetalol HCl","b3","L1300-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,BP2017,JP17,IP2010","074787,074989,075113,075133,075215,075223,075239,075240,075242,075303,075355,075431,075524,076051,079134,090699,200908,207743,207863,209603,211325","Cardiovascular Disease","Adrenergic Receptor","GPCR & G Protein","Labetalol HCl(AH-5158 hydrochloride,Labetalol hydrochloride,Sch-15719W) is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors, used in the treatment of high blood pressure.",364.87,"32780-64-6",72,197.33,8,21.93,"http://selleckchem.com/products/labetalol-hcl.html","C19H25ClN2O3","Hydrochloride","AH-5158 hydrochloride,Labetalol hydrochloride,Sch-15719W","Cl.CC(CCC1=CC=CC=C1)NCC(O)C2=CC(=C(O)C=C2)C(N)=O",2.737,1,4,8]
["S4292","Diphenidol HCl","c3","L1300-17","in 10mM DMSO","FDA,CFDA,DMF",null,"016033","Gastroenterology/Neurological Disease","AChR","Neuronal Signaling","Diphenidol HCl(Diphenidol hydrochloride) is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02, respectively, used in the treatment of vomiting and vertigo.",345.91,"3254-89-5",69,199.47,13,37.58,"http://selleckchem.com/products/diphenidol-hcl.html","C21H28ClNO","Hydrochloride","Diphenidol hydrochloride","Cl.OC(CCCN1CCCCC1)(C2=CC=CC=C2)C3=CC=CC=C3",4.774,0,0,6]
["S4293","Promethazine HCl","d3","L1300-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,BP2017,JP16,IP2010","040026,040372,040428,040449,040454,040471,040479,040500,040504,040515,040524,040558,040593,040596,040603,040622,040643,040673,040712,040713,040718,040737,040785,040791,040863,040882,040891,080629,080949,083204,083214,083312,083401,083403,083426,083532,083603,083604,083613,083658,083711,083712,083838,083955,084027,084080,084160,084166,084176,084214,084222,084223,084233,084539,084554,084555,084557,084591,085146,085385,085388,085664,085684,085986,086395,087518,089109,089463,089477,091054,091179,091675,209177","Respiratory Disease","Histamine Receptor","Neuronal Signaling","Promethazine HCl is a potent histamine H1 receptor antagonist, used as a sedative and antiallergic medication.",320.88,"58-33-3",64,199.45,64,199.45,"http://selleckchem.com/products/promethazine-hcl.html","C17H21ClN2S","Hydrochloride","N/A","Cl.CC(CN1C2=CC=CC=C2SC3=C1C=CC=C3)N(C)C",4.772,0,0,3]
["S4294","Procainamide HCl","e3","L1300-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,BP2017,JP16,IP2010","089256,089257","Cardiovascular Disease","DNA Methyltransferase,Sodium Channel","Transmembrane Transporters","Procainamide HCl is a sodium channel blocker, and also a DNA methyltransferase inhibitor, used in the treatment of cardiac arrhythmias.",271.79,"614-39-1",54,198.68,54,198.68,"http://selleckchem.com/products/procainamide-hcl.html","C13H22ClN3O","Hydrochloride","N/A","Cl.CCN(CC)CCNC(=O)C1=CC=C(N)C=C1",1.509,1,2,6]
["S4295","Meclofenamate Sodium","f3","L1300-17","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,USP39-NF34","070400,070401,071007,071008,071081,071362,071363,071468,071469,071640,071641,071684,071710,072077,072078,072262,072263,072809,072848","Neurological Disease","COX,FTO","Neuronal Signaling","Meclofenamate Sodium(CI 583) is a dual COX-1/COX-2 inhibitor with IC50 of 40 nM and 50 nM, respectively, used in the treatment of joint, muscular pain, arthritis and dysmenorrhea. Meclofenamate Sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat mass and obesity-associated (FTO) enzyme inhibitor.",318.13,"6385-02-0",63,198.03,63,198.03,"http://selleckchem.com/products/meclofenamate-sodium.html","C14H11Cl2NO2.Na","Sodium Salt","CI 583","CC1=C(Cl)C(=C(Cl)C=C1)NC2=CC=CC=C2C(=O)O[Na]",4.915,2,1,4]
["S4296","Salmeterol Xinafoate","g3","L1300-17","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","020236,020692","Immunology/Inflammation/Respiratory Disease","Adrenergic Receptor","GPCR & G Protein","Salmeterol Xinafoate(GR 33343X xinafoate,Salmetedur) is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms.",603.75,"94749-08-3",100,165.63,"<1",0,"http://selleckchem.com/products/salmeterol-xinafoate.html","C36H45NO7","xinafoate","GR 33343X xinafoate,Salmetedur","OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC2=CC=CC=C2.OC(=O)C3=C(O)C4=CC=CC=C4C=C3",3.673,2,5,17]
["S4297","Mupirocin","h3","L1300-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.7,KP Ⅹ,JP17,BP2017","065085,065123,065170,065192,090480,201587","Infection","DNA/RNA Synthesis","DNA Damage/DNA Repair","Mupirocin(BRL-4910A,Pseudomonic acid) is an isoleucyl t-RNA synthetase inhibitor, used in the treatment of bacterial skin infections.",500.62,"12650-69-0",100,199.75,46,91.89,"http://selleckchem.com/products/mupirocin.html","C26H44O9","free base","BRL-4910A,Pseudomonic acid","CC(O)C(C)C1OC1CC2COC(C\\C(C)=C\\C(=O)OCCCCCCCCC(O)=O)C(O)C2O",2.739,5,3,17]
["S4299","Dicoumarol","a4","L1300-17","in 10mM DMSO",null,"Ph.Int_6th;Martindale:The Extra Pharmacopoeia",null,"Hematology","PDHK","Metabolism","Dicoumarol is a competitive NADPH quinone oxidoreductase (NQO1) inhibitor,and used as an anticoagulant by interfering with the metabolism of vitamin K.",336.29,"66-76-2",67,199.23,"<1",0,"http://selleckchem.com/products/dicoumarol.html","C19H12O6","free base","Dicumarol","OC1=C(CC2=C(O)C3=C(OC2=O)C=CC=C3)C(=O)OC4=CC=CC=C14",2.789,4,2,2]
["S4301","(R)-(+)-Atenolol HCl","b4","L1300-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","072304,073025,073026,073315,073316,073317,073318,073352,073353,073457,073475,073476,073542,073543,073676,074052,074056,074099,074101,074120,074126,074127,074265,074499,076900,076907,077443,077877,078210,078254,078512","Cardiovascular Disease/Neurological Disease/Endocrinology","Adrenergic Receptor","Others","(R)-(+)-Atenolol binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists.",266.34,"56715-13-0",53,198.99,18,67.58,"http://selleckchem.com/products/atenolol.html","C9H16ClNO2","Hydrochloride","N/A","Cl.CC(=O)OC1CN2CCC1CC2",0.939,2,0,2]
["S4303","9-Aminoacridine","c4","L1300-17","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Others","Anti-infection","Microbiology","9-Aminoacridine (Aminacrine) is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix.",194.23,"90-45-9",38,195.64,"<1",0,"http://www.selleckchem.com/products/9-aminoacridine.html","C13H10N2","free base","Aminacrine","NC1=C2C=CC=CC2=NC3=CC=CC=C13",2.606,1,1,0]
["S4304","Anisindione","d4","L1300-17","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia","010909","Cardiovascular Disease","Others","Others","Anisindione is a synthetic anticoagulant and an indanedione derivative.",252.26,"117-37-3",50,198.21,0,0,"http://selleckchem.com/products/anisindione.html","C16H12O3",0,"N/A","COC1=CC=C(C=C1)C2C(=O)C3=C(C=CC=C3)C2=O",0,0,0,0]
["S4305","Anisotropine Methylbromide","e4","L1300-17","in 10mM DMSO","FDA,DMF",null,"086046","Gastroenterology","Others","Others","Anisotropine Methylbromide is a quaternary ammonium compound, used as treatment adjunct in peptic ulcer.",362.35,"80-50-2",25,68.99,72,198.7,"http://www.selleckchem.com/products/anisotropine-methylbromide.html","C17H32BrNO2","methylbromide","N/A","[Br-].CCCC(CCC)C(=O)OC1CC2CCC(C1)[N+]2(C)C",-0.169,2,0,7]
["S4307","Auranofin","f4","L1300-17","in 10mM DMSO","DMF,NDC,FDA","Martindale:The Extra Pharmacopoeia,JP17","018689","Immunology/Inflammation","Bacterial,Thioredoxin Reductase","Microbiology","Auranofin (Ridaura, SKF-39162) is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 μM. Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis.",678.48,"34031-32-8",100,147.39,-1,0,"http://www.selleckchem.com/products/auranofin.html","C20H34AuO9PS","Free Base","Ridaura, SKF39162","CCP(|[Au]SC1OC(COC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O)(CC)CC",1.407,9,0,14]
["S4308","Benzthiazide","g4","L1300-17","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP32-NF27","083206","Cardiovascular Disease/Metabolic Disease","Others","Others","Benzthiazide is a thiazide diuretic, promoting water loss from the body.",431.94,"91-33-8",86,199.1,"<1",0,"http://www.selleckchem.com/products/benzthiazide.html","C15H14ClN3O4S3","Free Base","Benzothiazide","N[S](=O)(=O)C1=CC2=C(C=C1Cl)N=C(CSCC3=CC=CC=C3)N[S]2(=O)=O",1.966,5,2,5]
["S4309","Bromocriptine Mesylate","h4","L1300-17","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37,IP2010","074631,075100,076962,077226,077646,078899","Endocrinology","Others","Others","Bromocriptine, an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.",750.7,"22260-51-1",100,133.21,-1,0,"http://www.selleckchem.com/products/bromocriptine-mesylate.html","C32H40BrN5O5.CH4O3S","Mesylate","N/A","CC(C)CC1N2C(=O)C(NC(=O)C3CN(C)C4CC5=C(Br)[NH]C6=C5C(=CC=C6)C4=C3)(OC2(O)C7CCCN7C1=O)C(C)C.C[S](O)(=O)=O",3.949,4,2,5]
["S4312","Carbadox","a5","L1300-17","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Infection","Others","Others","Carbadox is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease.",262.22,"6804-07-5",8,30.51,"<1",0,"http://www.selleckchem.com/products/carbadox.html","C11H10N4O4","Free Base","N/A","COC(=O)N/N=C/C1=[N+]([O-])C2=C(C=CC=C2)[N+](=C1)[O-]",-0.134,3,1,3]
["S4316","Clopamide","b5","L1300-17","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei,EP8.8,BP2017",null,"Cardiovascular Disease/Metabolic Disease","Others","Others","Clopamide is categorised as a thiazide-like diuretic and works in similar way as the thiazide diuretics do.",345.84,"636-54-4",69,199.51,-1,0,"http://www.selleck.cn/products/clopamide.html","C14H20ClN3O3S","Free Base","N/A","CC1CCCC(C)N1NC(=O)C2=CC=C(Cl)C(=C2)[S](N)(=O)=O",1.793,3,2,3]
["S4317","Clorgyline HCl","c5","L1300-17","in 10mM DMSO","DMF",null,null,"Psychotic disorders","MAO","Others","Clorgiline is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A).",308.63,"17780-75-5",62,200.89,-1,0,"http://www.selleckchem.com/products/clorgyline-hcl.html","C13H15Cl2NO.HCl","hydrochloride","N/A","Cl.CN(CCCOC1=CC=C(Cl)C=C1Cl)CC#C",4.917,1,0,6]
["S4322","Disopyramide Phosphate","d5","L1300-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","070101,070102,070138,070139,070173,070186,070187,070240,070241,070351,070352,070470,070471,070940,070941,071190,071191,071200","Cardiovascular Disease","Others","Others","Disopyramide (DISO) is a widely used Class 1a antiarrhythmic agent that is employed in the treatment of ventricular and supraventricular arrhythmias.",437.47,"22059-60-5",12,27.43,87,198.87,"http://www.selleckchem.com/products/disopyramide-phosphate.html","C21H32N3O5P","phosphate","N/A","CC(C)N(CCC(C(N)=O)(C1=CC=CC=C1)C2=NC=CC=C2)C(C)C.O[P](O)(O)=O",2.949,2,1,8]
["S4326","Ethoxzolamide","e5","L1300-17","in 10mM DMSO","FDA",null,"011047,016144","Inflammation/Neurological Disease/Ophthalmology","Carbonic Anhydrase","Others","Ethoxzolamide is an inhibitor of the metalloenzyme carbonic anhydrase, which inhibits hCA I, hCA II, hCA IV, hCA VI and hCA VII with Ki of 25 nM, 8 nM, 93 nM, 43 nM and 0.8 nM, respectively.",258.32,"452-35-7",51,197.43,"<1",0,"http://www.selleckchem.com/products/ethoxzolamide.html","C9H10N2O3S2","Free Base","N/A","CCOC1=CC=C2N=C(SC2=C1)[S](N)(=O)=O",1.493,4,1,3]
["S4330","Isoetharine Mesylate","f5","L1300-17","in 10mM DMSO","FDA,DMF","USP42-NF37","087858","Immunology","Others","Others","Isoetharine is a selective beta2-adrenergic receptor agonist, which gives quick relief for bronchospasm and asthma.",335.42,"7279-75-6",67,199.75,67,199.75,"http://www.selleckchem.com/products/isoetharine-mesylate.html","C14H25NO6S","mesylate","N/A","CCC(NC(C)C)C(O)C1=CC=C(O)C(=C1)O.C[S](O)(=O)=O",1.586,0,4,5]
["S4331","Meclocycline Sulfosalicylate","g5","L1300-17","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ","050518","Inflammation","Others","Others","Meclocycline is a tetracycline antibiotic. Meclocycline sulfosalicylate prevents bacterial protein synthesis through 30S ribosome-mediated chain elongation and blocks amino-acyl tRNA A-site binding.",695.05,"73816-42-9",100,143.87,-1,0,"http://www.selleckchem.com/products/meclocycline-sulfosalicylate.html","C22H21ClN2O8.C7H6O6S","sulfosalicylate","N/A","CN(C)C1C2C(O)C3C(=C)C4=C(C(=CC=C4Cl)O)C(=O)C3=C(O)C2(O)C(=O)C(=C1O)C(N)=O.OC(=O)C5=C(O)C=CC(=C5)[S](O)(=O)=O",-2.767,4,6,4]
["S4332","Medrysone","h5","L1300-17","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia","016624","Immunology/Inflammation","Others","Others",0,344.49,"2668-66-8",69,200.3,-1,0,"http://www.selleckchem.com/products/medrysone.html","C22H32O3","Free Base","N/A","CC1CC2C3CCC(C(C)=O)C3(C)CC(O)C2C4(C)CCC(=O)C=C14",2.942,2,1,1]
["S4334","Mesoridazine Besylate","a6","L1300-17","in 10mM DMSO","FDA,DMF","USP42-NF37","016774,016775,016997","Psychotic disorders","Others","Others",0,544.75,"32672-69-8",100,183.57,100,183.57,"http://www.selleckchem.com/products/mesoridazine-besylate.html","C27H32N2O4S3","besylate","N/A","CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)[S](C)=O.O[S](=O)(=O)C5=CC=CC=C5",5.614,1,0,5]
["S4335","Metaproterenol Sulfate","b6","L1300-17","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","070804,070805,071013,071014,071018,071275,071656,071726,071786,071805,071806,071855,072024,072025,072054,072055,072190,072519,072520,072761,072795,073013,073034,073632,074702,075235,075402,075403,075586","Immunology","Others","Others",0,520.59,"5874-97-5",100,192.09,100,192.09,"http://www.selleckchem.com/products/metaproterenol-sulfate.html","C22H36N2O10S","sulfate","Orciprenaline Sulfate","CC(C)NCC(O)C1=CC(=CC(=C1)O)O.CC(C)NCC(O)C2=CC(=CC(=C2)O)O.O[S](O)(=O)=O",1.591,0,8,8]
["S4336","Metaraminol Bitartrate","c6","L1300-17","in 10mM DMSO","FDA,CFDA,HMA","USP42-NF37","080431,080722,083363,086418","Cardiovascular Disease","Others","Others",0,317.29,"33402-03-8",63,198.56,63,198.56,"http://www.selleckchem.com/products/metaraminol-bitartrate.html","C13H19NO8","bitartrate","Metaradrine Bitartrate","CC(N)C(O)C1=CC=CC(=C1)O.OC(C(O)C(O)=O)C(O)=O",-3.582,2,5,5]
["S4338","Methoxamine HCl","d6","L1300-17","in 10mM DMSO","FDA,CFDA","Martindale:The Extra Pharmacopoeia,BP2017,IP2010","006772","Cardiovascular Disease","Others","Others","Methoxamine is an α1-adrenergic receptor agonist, it induces vasoconstriction of skin and splanchnic blood vessels.",247.72,"61-16-5",50,201.84,-1,0,"http://www.selleckchem.com/products/methoxamine-hcl.html","C11H17NO3.HCl","Hydrochloride","Vasoxine HCl","Cl.COC1=CC(=C(OC)C=C1)C(O)C(C)N",1.151,2,2,4]
["S4339","Meticrane","e6","L1300-17","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Metabolic Disease","Chloride Channel,Sodium Channel","Transmembrane Transporters","Meticrane is a diuretic that inhibits the reabsorption of sodium and chloride ions in the distal convoluted tubule. Meticrane is used to treat essential hypertension.",275.34,"1084-65-7",55,199.75,"<1",0,"http://www.selleckchem.com/products/meticrane.html","C10H13NO4S2","Free Base","N/A","CC1=C(C=C2C(=C1)CCC[S]2(=O)=O)[S](N)(=O)=O",1.078,4,1,1]
["S4343","Oxethazaine","f6","L1300-17","in 10mM DMSO","PMDA","KP Ⅹ,JP17",null,"Neurological Disease","Others","Others","Oxethazaine is a strong local anaesthetic, which acts in a number of ways to numb the walls of the stomach and relieve the pain associated with hyperacidic conditions.",467.64,"126-27-2",87,186.04,"<1",0,"http://selleckchem.com/products/oxethazaine.html","C28H41N3O3","free base","Oxethacaine","CN(C(=O)CN(CCO)CC(=O)N(C)C(C)(C)CC1=CC=CC=C1)C(C)(C)CC2=CC=CC=C2",3.286,2,1,12]
["S4344","Oxprenolol HCl","g6","L1300-17","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,IP2010","018166","Cardiovascular Disease","Adrenergic Receptor","Others","Oxprenolol is a non-selective beta blocker with some intrinsic sympathomimetic activity.",301.81,"6452-73-9",60,198.8,-1,0,"http://www.selleckchem.com/products/oxprenolol-hcl.html","C15H23NO3.HCl","hydrochloride","N/A","Cl.CC(C)NCC(O)COC1=CC=CC=C1OCC=C",2.614,2,2,9]
["S4345","Pentoxifylline","h6","L1300-17","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,BP2017","074425,074874,074877,074878,075028,075093,075107,075191,075199","Angiology","PDE","Metabolism","Pentoxifylline is a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF and leukotriene synthesis, and reduces inflammation and innate immunity.",278.31,"6493-05-6",55,197.62,55,197.62,"http://www.selleckchem.com/products/pentoxifylline.html","C13H18N4O3","Free Base","N/A","C[N]1C=NC2=C1C(=O)N(CCCCC(C)=O)C(=O)N2C",0.507,4,0,5]
["S4349","Procyclidine HCl","a7","L1300-17","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017,IP2010","009818","Neurological Disease","NMDAR","Others","Procyclidine HCl blocks the effects of certain chemicals in the brain, and thus is used to treat Parkinson's disease or extrapyramidal side-effects caused by other medicines.",323.9,"1508-76-5",64,197.59,14,43.22,"http://www.selleckchem.com/products/procyclidine-hcl.html","C19H30ClNO","hydrochloride","N/A","Cl.OC(CCN1CCCC1)(C2CCCCC2)C3=CC=CC=C3",4.343,0,0,5]
["S4351","Ractopamine HCl","b7","L1300-17","in 10mM DMSO",null,"USP42-NF37",null,"Cardiovascular Disease/Metabolic Disease","Others","Others","Ractopamine HCl (RAC), a beta-agonist with established nutrient partitioning capabilities, promotes skeletal muscle accretion at the expense of fat deposition.",337.84,"90274-24-1",67,198.32,67,198.32,"http://www.selleckchem.com/products/ractopamine-hcl.html","C18H24ClNO3","hydrochloride","N/A","Cl.CC(CCC1=CC=C(O)C=C1)NCC(O)C2=CC=C(O)C=C2",3.493,0,4,7]
["S4353","Terfenadine","c7","L1300-17","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017",null,"Immunology","Calcium Channel,Caspase,Histamine Receptor,NCX,Potassium Channel","Transmembrane Transporters","Terfenadine is an antihistamine, generally completely metabolizes to the active form fexofenadine in the liver by the enzyme cytochrome P450 CYP3A4 isoform.  Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.",471.67,"50679-08-8",94,199.29,"<1",0,"http://www.selleckchem.com/products/terfenadine.html","C32H41NO2","Free Base","N/A","CC(C)(C)C1=CC=C(C=C1)C(O)CCCN2CCC(CC2)C(O)(C3=CC=CC=C3)C4=CC=CC=C4",6.498,0,1,9]
["S4354","Thiostrepton","d7","L1300-17","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37",null,"Infection","Others","Others","Thiostrepton (Alaninamide, Bryamycin, Thiactin) is a natural cyclic oligopeptide antibiotic, derived from several strains of strepromycetes.",1664.89,"1393-48-2",100,60.06,-1,0,"http://www.selleckchem.com/products/thiostrepton.html","C72H85N19O18S5","Free Base","Alaninamide, Bryamycin, Thiactin","CCC(C)C1NC2C=CC3=C(C=C(N=C3C2O)C(=O)OC(C)C4NC(=O)C5=CSC(=N5)C(NC(=O)C6CSC(=N6)\\C(NC(=O)C(NC(=O)C7=CSC(=N7)C8(CCC(=NC8C9=CSC4=N9)C%10=NC(=CS%10)C(=O)NC(=C)C(=O)NC(=C)C(N)=O)NC(=O)C(C)NC(=O)C(=C)NC(=O)C(C)NC1=O)C(C)O)=C\\C)C(C)(O)C(C)O)C(C)O",-1.361,20,16,12]
["S4357","Tacrine HCl","e7","L1300-17","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP39-NF34","020070","Neurological Disease","AChR","Neuronal Signaling","Tacrine is a centrally acting anticholinesterase and indirect cholinergic agonist. Tacrine hydrochloride hydrate is an inhibitor of both acetyl (AChE) and butyryl-cholinestrase (BChE) with IC50s of 31 nM and 25.6 nM, respectively.",234.72,"1684-40-8",46,195.98,46,195.98,"http://www.selleckchem.com/products/tacrine-hcl.html","C13H14N2.HCl","hydrochlorid","N/A","Cl.NC1=C2C=CC=CC2=NC3=C1CCCC3",3.172,1,1,0]
["S4358","Pimozide","f7","L1300-17","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017,IP2010","204521","Psychotic disorders","5-HT Receptor,Adrenergic Receptor,Dopamine Receptor,STAT","Neuronal Signaling","Pimozide (Orap, R6238) is an antagonist of Dopamine Receptors with Ki of 0.83 nM, 3.0 nM and 6600 nM for dopamine D3, D2 and D1 receptors, respectively. Pimozide also exhibits binding affinity at 5-HT1A and α1-adrenoceptor with Ki of 310 nM and 39 nM, respectively. Pimozide is an antipsychotic drug with anti-tumor activity and suppresses STAT3 and STAT5 activity.",461.55,"2062-78-4",92,199.33,"<1",0,"http://www.selleckchem.com/products/pimozide.html","C28H29F2N3O","Free Base","Orap, R6238","FC1=CC=C(C=C1)C(CCCN2CCC(CC2)N3C(=O)NC4=CC=CC=C34)C5=CC=C(F)C=C5",5.521,1,1,7]
["S4361","Cinoxacin","g7","L1300-17","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,JP17,USP39-NF34","073005,073006","Infection","Bacterial","Others","Cinoxacin is a chemotherapeutic agent that inhibits bacterial DNA synthesis.",262.22,"28657-80-9",7,26.7,0,0,"http://selleckchem.com/products/cinoxacin.html","C12H10N2O5",0,"N/A","CCN1N=C(C(O)=O)C(=O)C2=C1C=C3OCOC3=C2",0,0,0,0]
["S4362","Glafenine HCl","h7","L1300-17","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Inflammation","Others","Others","Glafenine is an anthranilic acid derivative with analgesic properties, which has been used previously in the treatment of pain.",409.26,"65513-72-6",81,197.92,7,17.1,"http://www.selleckchem.com/products/glafenine-hcl.html","C19H18Cl2N2O4","hydrochloride","N/A","Cl.OCC(O)COC(=O)C1=CC=CC=C1NC2=CC=NC3=CC(=CC=C23)Cl",3.418,3,3,7]
["S4365","Phthalylsulfacetamide","a8","L1300-17","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Infection","Others","Others","Phthalylsulfacetamide is a sulfonamide with a high solubility and suited for systemic use for diseases of the eye.",362.36,"131-69-1",72,198.7,"<1",0,"http://www.selleckchem.com/products/phthalylsulfacetamide.html","C16H14N2O6S","Free Base","N/A","CC(=O)N[S](=O)(=O)C1=CC=C(NC(=O)C2=C(C=CC=C2)C(O)=O)C=C1",0.939,5,2,5]
["S4366","Pinacidil","b8","L1300-17","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia","019456","Cardiovascular Disease","Others","Others","Pinacidil is known to augment a time-independent outward current in cardiac tissues by activating the ATP-regulated potassium channels.",263.34,"85371-64-8",53,201.26,-1,0,"http://www.selleckchem.com/products/pinacidil.html","C13H19N5.H2O","Free Base","N/A","O.CC(NC(NC1=CC=NC=C1)=NC#N)C(C)(C)C",1.624,2,2,5]
["S4367","Suxibuzone","c8","L1300-17","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Inflammation","Others","Others","Suxibuzone is a prodrug of the non steroidal anti inflammatory drug phenylbutazone, and is commonly used in horses.",438.47,"27470-51-5",88,200.7,-1,0,"http://www.selleckchem.com/products/suxibuzone.html","C24H26N2O6","Free Base","N/A","CCCCC1(COC(=O)CCC(O)=O)C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3",3.504,5,0,11]
["S4368","Carbenoxolone Sodium","d8","L1300-17","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,BP2015,IP2010",null,"Infection","Others","Others","Carbenoxolone, a synthetic derivative of glycyrrhetinic acid, is also used as a blocker of the enzyme 11β-hydroxysteroid dehydrogenase (11β-HSD), of pannexon membrane channels (comprising 6 subunits of pannexin) and the related innexon channels.",614.72,"7421-40-1",23,37.42,100,162.68,"http://www.selleckchem.com/products/carbenoxolone-sodium.html","C34H48Na2O7","disodiuM","N/A","[Na+].[Na+].CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C([O-])=O)OC(=O)CCC([O-])=O",2.933,3,0,6]
["S4373","Dicyclomine HCl","e8","L1300-17","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37,KP Ⅹ,IP2010","040161,040169,040204,040230,040317,040319,080614,083179,084285,084361,084479,084505,084600,085082,085223,088585,089361,206468,207076,207084,208353,210257,210788,210979,212058","Gastroenterology","Others","Others","Dicyclomine is an anticholinergic drug, a chemical released from nerves that stimulates muscles, by blocking the receptors for acetylcholine on smooth muscle (a type of muscle).",345.95,"67-92-5",22,63.59,69,199.45,"http://www.selleckchem.com/products/dicyclomine-hcl.html","C19H36ClNO2","Hydrochloride","Dicycloverine HCl","Cl.CCN(CC)CCOC(=O)C1(CCCCC1)C2CCCCC2",5.487,2,0,8]
["S4375","Mepenzolate Bromide","f8","L1300-17","in 10mM DMSO","FDA,DMF,PMDA","Martindale:The Extra Pharmacopoeia,JP17","010679","Gastroenterology","Others","Others","Mepenzolate is a post-ganglionic parasympathetic inhibitor, it decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon.",420.34,"76-90-4",41,199.34,1,4.86,"http://www.selleckchem.com/products/mepenzolate-bromide.html","C21H26BrNO3","bromide","N/A","[Br-].C[N+]1(C)CCC(CC1)OC(=O)C(O)(C2=CC=CC=C2)C3=CC=CC=C3",-1.048,2,0,5]
["S4376","Aceclidine HCl","g8","L1300-17","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Ophthalmology","Others","Others","Aceclidine is a parasympathomimetic miotic agent used to decreases intraocular pressure.",205.68,"6109-70-2",41,199.34,41,199.34,"http://www.selleckchem.com/products/aceclidine-hcl.html","C9H16ClNO2","hydrochloride","N/A","Cl.CC(=O)OC1CN2CCC1CC2",0.939,2,0,2]
["S4377","Imipramine HCl","h8","L1300-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,IP2010","040751,040903,081048,081049,081050,083729,083745,083799,084252,084869,084936,084937,085133,085200,085220,085221,085875,085877,085878,086267,086268,086269,086765,087619,087631,087776,087846,088036,088222,088223,088262,088276,088292,089422,089497,090441","Psychotic disorders","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Imipramine (Melipramine,G 22355) is a tricyclic antidepressant (TCA) of the dibenzazepine group, mainly used in the treatment of major depression and enuresis (inability to control urination).",316.87,"113-52-0",63,198.82,63,198.82,"http://www.selleckchem.com/products/imipramine-hcl.html","C19H25ClN2","hydrochloride","Melipramine HCl,G 22355","Cl.CN(C)CCCN1C2=C(CCC3=C1C=CC=C3)C=CC=C2",4.769,0,0,4]
["S4381","Proadifen HCl","a9","L1300-17","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","CYP450","Others","Proadifen is an inhibitor of cytochrome P450 enzymes, preventing some types of drug metabolism.",390.01,"62-68-0",77,197.43,77,197.43,"http://www.selleckchem.com/products/proadifen-hcl.html","C23H32ClNO2","hydrochloride","SKF 525-A HCl","Cl.CCCC(C(=O)OCCN(CC)CC)(C1=CC=CC=C1)C2=CC=CC=C2",5.762,2,0,11]
["S4382","Pyrilamine Maleate","b9","L1300-17","in 10mM DMSO","FDA,NDC,DMF","USP42-NF37,IP2010","080808,085231","Immunology","Histamine Receptor","Neuronal Signaling","Pyrilamine Maleate (Mepyramine)is a histamine H1 receptor inverse agonist, it binds to a G protein-coupled form of the receptor and promotes a G protein-coupled inactive state of the H1 receptor that interferes with the Gq/11-mediated signaling.",401.46,"59-33-6",80,199.27,80,199.27,"https://www.selleckchem.com/products/pyrilamine-maleate.html","C17H23N3O1.C4H4O4","maleate","Mepyramine Maleate","COC1=CC=C(CN(CCN(C)C)C2=CC=CC=N2)C=C1.OC(=O)\\C=C/C(O)=O",0.09,4,0,9]
["S4385","Fosfomycin Tromethamine","c9","L1300-17","in 10mM DMSO","FDA,NDC,DMF","USP42-NF37","050717","Infection","Others","Others","Fosfomycin tromethamine is a phosphonic acid bactericidal agent with in vitro activity against most urinary tract pathogens.",259.19,"78964-85-9",51,196.77,51,196.77,"http://www.selleckchem.com/products/fosfomycin-tromethamine.html","C7H18NO7P","tromethamine","Phosphomycin Tromethamine, Phosphonomycin Tromethamine","CC1OC1[P](O)(O)=O.NC(CO)(CO)CO",-2.699,1,4,4]
["S4387","Bendroflumethiazide","d9","L1300-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","012164,012164,012164","Cardiovascular Disease/Metabolic Disease","Others","Others",0,421.41,"73-48-3",85,201.7,0,0,"http://selleckchem.com/products/bendroflumethiazide.html","C15H14F3N3O4S2",0,"Bendrofluazide","N[S](=O)(=O)C1=CC2=C(NC(CC3=CC=CC=C3)N[S]2(=O)=O)C=C1C(F)(F)F",0,0,0,0]
["S4388","Bentiromide","e9","L1300-17","in 10mM DMSO","FDA,DMF,PMDA","Martindale:The Extra Pharmacopoeia","018366","Diagnosis","Others","Others","Bentiromide is a peptide which is broken down in the pancreas by chymotrypsin. The bentiromide test is a test of pancreatic exocrine function.",404.42,"37106-97-1",81,200.29,0,0,"http://selleckchem.com/products/bentiromide.html","C23H20N2O5",0,"N/A","OC(=O)C1=CC=C(NC(=O)C(CC2=CC=C(O)C=C2)NC(=O)C3=CC=CC=C3)C=C1",0,0,0,0]
["S4389","Bephenium Hydroxynaphthoate","f9","L1300-17","in 10mM DMSO",null,"Ph.Int_6th;Martindale:The Extra Pharmacopoeia",null,"Parasite","AChR,Parasite","Neuronal Signaling","Bephenium(NSC 759245) is an activator of B-type Acetylcholine receptor (AChR). Bephenium selectively activates the Hco-L-AChR1 subtype made of Hco-UNC-29.1, Hco-UNC-38, Hco-UNC-63, Hco-ACR-8 subunits. Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis.",443.53,"3818-50-6",88,198.41,"<1",0,"http://www.selleckchem.com/products/bephenium-hydroxynaphthoate.html","C28H29NO4","hydroxynaphthoa","NSC 759245","C[N+](C)(CCOC1=CC=CC=C1)CC2=CC=CC=C2.OC3=C(C=C4C=CC=CC4=C3)C([O-])=O",2.833,1,1,7]
["S4391","Camylofin Chlorhydrate","g9","L1300-17","in 10mM DMSO","CFDA",null,null,"Neurological Disease","Others","Others",0,393.39,"54-30-8",78,198.28,78,198.28,"http://www.selleckchem.com/products/camylofin-chlorhydrate.html","C19H34Cl2N2O2","chlorhydrate","Camylofine Chlorhydrate","Cl.Cl.CCN(CC)CCNC(C(=O)OCCC(C)C)C1=CC=CC=C1",4.391,2,1,12]
["S4393","Cephapirin Sodium","h9","L1300-17","in 10mM DMSO","FDA,DMF","USP39-NF34","062720,062723","Infection","Antibiotics,Bacterial","Microbiology","Cephapirin Sodium (Cefapirin) is the sodium salt form of cephapirin, a semi-synthetic, first-generation cephalosporin antibiotic with bactericidal activity.Cephapirin Sodium is effective against gram-negative and gram-positive organisms.",445.45,"24356-60-3",89,199.8,0,0,"http://selleckchem.com/products/cephapirin-sodium.html","C17H16N3O6S2.Na","sodium","Cefapirin Sodium","[Na+].CC(=O)OCC1=C(N2C(SC1)C(NC(=O)CSC3=CC=NC=C3)C2=O)C([O-])=O",0,0,0,0]
["S4394","Clofoctol","a10","L1300-17","in 10mM DMSO","marketed in France and Italy","Martindale:The Extra Pharmacopoeia",null,"Infection","Others","Others",0,365.34,"37693-01-9",73,199.81,"<1",0,"http://www.selleckchem.com/products/clofoctol.html","C21H26Cl2O","Free Base","N/A","CC(C)(C)CC(C)(C)C1=CC(=C(O)C=C1)CC2=CC=C(Cl)C=C2Cl",7.662,0,1,5]
["S4396","Digoxigenin","b10","L1300-17","in 10mM DMSO",null,"USP42-NF37",null,"Cardiovascular Disease","Others","Others",0,390.51,"1672-46-4",78,199.74,-1,0,"http://www.selleckchem.com/products/digoxigenin.html","C23H34O5","Free Base","Lanadigigenin","CC12CCC(O)CC1CCC3C2CC(O)C4(C)C(CCC34O)C5=CC(=O)OC5",2.276,2,2,1]
["S4402","Oxeladin Citrate","c10","L1300-17","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017",null,"Respiratory Disease","Others","Others","Oxeladin citrate (OL), a cough suppressant, is a highly potent and effective drug applied in the treatment of all types of cough of various etiologies.",527.6,"52432-72-1",100,189.54,100,189.54,"http://www.selleckchem.com/products/oxeladin-citrate.html","C20H33NO3.C6H8O7","citrate","OL","CCN(CC)CCOCCOC(=O)C(CC)(CC)C1=CC=CC=C1.OC(=O)CC(O)(CC(O)=O)C(O)=O",-0.137,6,0,18]
["S4404","Pasiniazid","d10","L1300-17","in 10mM DMSO","CFDA",null,null,"Infection","Bacterial","Microbiology","Pasiniazid(Paraniazide,Pasiniazide) is a composition of isoniazid and 4-aminosalicylic acid, used to treat tuberculosis patients.",290.27,"2066-89-9",58,199.81,"<1",0,"http://www.selleckchem.com/products/pasiniazid.html","C6H7N3O.C7H7NO3","Isonicotinic","Paraniazide,Pasiniazide","NNC(=O)C1=CC=NC=C1.NC2=CC(=C(C=C2)C(O)=O)O",-0.34,3,4,2]
["S4406","Pindolol","e10","L1300-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017,IP2010","073609,073661,073687,074013,074018,074019,074063,074123,074125,074437,074474,205415,209866","Cardiovascular Disease","5-HT Receptor","Others",0,248.32,"13523-86-9",50,201.35,-1,0,"http://www.selleckchem.com/products/pindolol.html","C14H20N2O2","Free Base","N/A","CC(C)NCC(O)COC1=C2C=C[NH]C2=CC=C1",1.925,1,3,6]
["S4414","Sodium 4-aminohippurate","f10","L1300-17","in 10mM DMSO","FDA，PMDA",null,"089821,005619","Others","Others","Others","Sodium 4-aminohippurate(Aminohippurate sodium) is a derivative of hippuric acid.",216.17,"94-16-6",43,198.92,43,198.92,"https://www.selleckchem.com/products/sodium-4-aminohippurate.html","C9H9N2NaO3","Sodium","Aminohippurate sodium","[Na+].NC1=CC=C(C=C1)C(=O)NCC([O-])=O",-1.701,1,2,3]
["S4415","Misoprostol","g10","L1300-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,Ph.Int_6th,BP2017,IP2010","076095,091667","Endocrinology","PGES,Prostaglandin Receptor","GPCR & G Protein","Misoprostol(SC29333) is a synthetic prostaglandin E1 (PGE1) analog that is used to prevent gastric ulcers, to treat missed miscarriage, to induce labor, and to induce abortion.",382.54,"59122-46-2",76,198.67,0,0,"http://selleckchem.com/products/misoprostol.html","C22H38O5",0,"SC-29333","CCCCC(C)(O)C/C=C/C1C(O)CC(=O)C1CCCCCCC(=O)OC",0,0,0,0]
["S4416","Trimipramine Maleate","h10","L1300-17","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","071283,071284,071285,077361,208127","Psychotic disorders","Others","Others",0,410.51,"521-78-8",82,199.75,"<1",0,"http://www.selleckchem.com/products/trimipramine-maleate.html","C24H30N2O4","maleate","N/A","CC(CN(C)C)CN1C2=C(CCC3=CC=CC=C13)C=CC=C2.OC(=O)\\C=C/C(O)=O",1.84,2,0,6]
["S4420","Mefloquine HCl","a11","L1300-17","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","019578,076175,076392,076523,077699","Infection/Parasitology","Anti-infection","Microbiology","Mefloquine HCl(Mefloquin hydrochloride) is a blood schizonticide by inhibiting hemozoin formation, used as an antimalarial drug.",414.77,"51773-92-3",82,197.7,"<1",0,"http://selleckchem.com/products/mefloquine-hcl.html","C17H17ClF6N2O","Hydrochloride","Mefloquin hydrochloride","Cl.OC(C1CCCCN1)C2=CC(=NC3=C(C=CC=C23)C(F)(F)F)C(F)(F)F",4.684,1,2,4]
["S4502","Eltrombopag","b11","L1300-17","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","206788,208815,209938","Hematology","TpoR","Immunology & Inflammation","Eltrombopag (SB-497115), a member of the biarylhydrazone class, is a nonpeptide agonist of the thrombopoietin receptor (TpoR), used to treat chronic hepatitis C-associated thrombocytopenia and chronic immune (idiopathic) thrombocytopenia (ITP).",442.47,"496775-61-2",26,58.76,"<1",0,"http://selleckchem.com/products/eltrombopag.html","C25H22N4O4","Free Base","SB-497115","CC1=CC=C(C=C1C)N2N=C(C)C(=N/NC3=CC=CC(=C3O)C4=CC(=CC=C4)C(O)=O)/C2=O",4.702,4,2,5]
["S4503","Calcium D-Panthotenate","c11","L1300-17","in 10mM DMSO","NDC",null,null,"Others","Vitamin","Metabolism","Calcium D-Panthotenate (D-Pantothenic Acid Calcium), also called vitamin B5 Calcium, is a water-soluble vitamin and an essential nutrient for many animals.",476.53,"137-08-6",44,92.33,44,92.33,"http://selleckchem.com/products/calcium-d-panthotenate.html","C18H32CaN2O10","free base","D-Pantothenic Acid Calcium","CC(C)(CO)C(O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)C(O)C(C)(C)CO",-1.935,6,6,16]
["S4504","6-Mercaptopurine (6-MP) Monohydrate","d11","L1300-17","in 10mM DMSO","DMF","BP2019",null,"Cancer/Hematology","DNA/RNA Synthesis","DNA Damage/DNA Repair","6-Mercaptopurine (6-MP) Monohydrate is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.",170.19,"6112-76-1",34,199.78,"<1",0,"http://selleckchem.com/products/6-mercaptopurine-6-mp-monohydrate.html","C5H6N4OS","free base","N/A","O.S=C1N=CNC2=C1[NH]C=N2",0.16,2,2,0]
["S4505","Vinblastine (NSC-49842) sulfate","e11","L1300-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","089011,089311,089365,089395,089515,089565","Cancer/Respiratory Disease","AChR,Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,Autophagy,Microtubule Associated","Cytoskeletal Signaling","Vinblastine sulfate (NSC49842, Vincaleukoblastine sulfate salt, 29060-LE, Exal, Velban, Velbe) inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM in a cell-free assay, used to treat certain kinds of cancer. Vinblastine sulfate induces autophagy and apoptosis.",909.05,"143-67-9",100,110,"<1",0,"http://selleckchem.com/products/vinblastine-sulfate.html","C46H58N4O9.H2SO4","sulfate","Vincaleukoblastine sulfate salt, 29060-LE, Exal, Velban, Velbe","CCC1(O)CC2CN(CCC3=C([NH]C4=CC=CC=C34)C(C2)(C(=O)OC)C5=C(OC)C=C6N(C)C7C(O)(C(OC(C)=O)C8(CC)C=CCN9CCC7(C89)C6=C5)C(=O)OC)C1.O[S](O)(=O)=O",4.28,7,1,10]
["S4506","Acetazolamide","f11","L1300-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","040195,040904,083320,084498,084840,087654,087686,088882,089753,090779,203434,204691,205301,205530,207659,209734,210423","Metabolic Disease/Neurological Disease/Ophthalmology","Carbonic Anhydrase","Metabolism","Acetazolamide (Diamox), a potent carbonic anhydrase (CA) inhibitor, is commonly used in clinical practice as an immediate and readily available option for acute reduction of intraocular pressure(IOP).",222.25,"59-66-5",44,197.98,"<1",0,"http://selleckchem.com/products/acetazolamide.html","C4H6N4O3S2","free base","Diamox","CC(=O)NC1=NN=C(S1)[S](N)(=O)=O",-1.329,5,2,2]
["S4507","17-Hydroxyprogesterone","g11","L1300-17","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Others","Estrogen/progestogen Receptor","Endocrinology & Hormones","17-Hydroxyprogesterone (17-OHP) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.",330.46,"68-96-2",66,199.72,"<1",0,"http://selleckchem.com/products/17-hydroxyprogesterone.html","C21H30O3","free base","N/A","CC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C",3.124,2,0,1]
["S4509","4-Aminoantipyrine","h11","L1300-17","in 10mM DMSO",null,"USP42-NF37;IP2010",null,"Inflammation/Neurological Disease","COX","Immunology & Inflammation","4-Aminoantipyrine(Ampyrone) is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. It is used as a reagent for biochemical reactions producing peroxides or phenols.",203.24,"83-07-8",40,196.81,40,196.81,"http://selleckchem.com/products/4-aminoantipyrine.html","C11H13N3O","free base","Ampyrone, NSC 60242, Metapirazone, Solnapyrin-A, Solvapyrin-A,  Minoazophene, Aminoazophene,  Aminoantipyrin","CN1N(C2=CC=CC=C2)C(=O)C(=C1C)N",0.021,1,1,1]
["S4510","4-Aminobenzoic acid","a2","L1300-18","in 10mM DMSO",null,"EP9.2;BP2017;IP2010",null,"Others","Others","Others","4-Aminobenzoic acid (para-Aminobenzoic acid) is an intermediate in the synthesis of tetrahydrofolic acid in many non-mammalian organisms, including bacteria and fungi.",137.14,"150-13-0",27,196.88,"<1",0,"http://selleckchem.com/products/4-aminobenzoic-acid.html","C7H7NO2","free base","para-Aminobenzoic acid","NC1=CC=C(C=C1)C(O)=O",0.713,1,1,1]
["S4512","Aceglutamide","b2","L1300-18","in 10mM DMSO","DMF,CFDA","JP17;Martindale:The Extra Pharmacopoeia",null,"Inflammation/Neurological Disease","Others","Others","Aceglutamide (α-N-Acetyl-L-glutamine, N2-Acetylglutamine) is a psychostimulant, nootropic agent which functions as a prodrug to glutamine with improved potency and stability.",188.18,"2490-97-3",37,196.62,37,196.62,"http://selleckchem.com/products/aceglutamide.html","C7H12N2O4","free base","α-N-Acetyl-L-glutamine, N2-Acetylglutamine","CC(=O)NC(CCC(N)=O)C(O)=O",-1.587,3,2,5]
["S4514","Acetylleucine","c2","L1300-18","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Others","Others","Acetylleucine (N-acetyl-L-leucine) is a drug used in the treatment of vertigo.",173.21,"99-15-0",34,196.29,"<1",0,"http://selleckchem.com/products/acetylleucine.html","C8H15NO3","free base","N-acetyl-L-leucine","CC(C)CC(NC(C)=O)C(O)=O",0.571,2,1,4]
["S4515","Ademetionine disulfate tosylate","d2","L1300-18","in 10mM DMSO","CFDA","USP36-NF31;Martindale:The Extra Pharmacopoeia",null,"Inflammation/Psychotic disorders","Anti-infection","Immunology & Inflammation","Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease.",766.8,"97540-22-2",79,103.03,79,103.03,"http://selleckchem.com/products/ademetionine-disulfate-tosylate.html","C22H34N6O16S4","disulfate tosylate","N/A","C[S+](CCC(N)C([O-])=O)CC1OC(C(O)C1O)[N]2C=NC3=C(N)N=CN=C23.CC4=CC=C(C=C4)[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O",-2.814,4,4,8]
["S4516","(+)-Camphor","e2","L1300-18","in 10mM DMSO","DMF,CFDA,NDC","USP42-NF37;EP9.1;BP2017;IP2010;Martindale:The Extra Pharmacopoeia",null,"Immunology/Inflammation","Fungal,TRP Channel","Transmembrane Transporters","Camphor is a waxy, flammable, white or transparent solid with a strong aroma, often used to relieve pain, reduce itching and treat fungal infections. It can activate TRPV1  and TRPV3.",152.23,"464-49-3",30,197.07,"<1",0,"http://selleckchem.com/products/positive-rotation-camphor.html","C10H16O","free base","D-(+)-camphor, (1R)-(+)-camphor","CC1(C)C2CCC1(C)C(=O)C2",2.075,1,0,0]
["S4517","Cefotaxime sodium","f2","L1300-18","in 10mM DMSO","FDA,DMF,CFDA,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","065124,065197,065290,065292,065293,065348,065516,065517,203132","Infection","Antibiotics,Antibiotics for Plant Cell Culture,Bacterial","Microbiology","Cefotaxime sodium(HR-756) salt is a third-generation cephalosporin antibiotic; broad-spectrum antibiotic with activity against numerous Gram-positive and Gram-negative bacteria.",477.45,"64485-93-4",95,198.97,95,198.97,"http://selleckchem.com/products/cefotaxime-sodium.html","C16H17N5O7S2.Na","Sodium Salt","HR-756","[Na+].CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)COC(C)=O)C3=CSC(=N3)N",-2.384,7,2,8]
["S4518","Chloroxylenol","g2","L1300-18","in 10mM DMSO","DMF,NDC,HMA","USP42-NF37;BP2019;IP2010;Martindale:The Extra Pharmacopoeia",null,"Others","Antiviral,Bacterial","Microbiology","Chloroxylenol is a broad-spectrum antimicrobial chemical compound used to control bacteria, algae, fungi and virus.",156.61,"88-04-0",31,197.94,"<1",0,"http://selleckchem.com/products/chloroxylenol.html","C8H9ClO","free base","N/A","CC1=CC(=CC(=C1Cl)C)O",3.224,0,1,0]
["S4520","2-Aminoheptane","h2","L1300-18","in 10mM DMSO",null,"USP42-NF37",null,"Inflammation","Others","Others","2-Aminoheptane (Tuaminoheptanez, Tuamine, Heptamine, 1-Methylhexylamine, 2-Heptylamine) is a nasal decongestant drug which is a sympathomimetic stimulant and vasoconstrictor.",115.22,"123-82-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/2-aminoheptane.html","C7H17N","Free Base","Tuaminoheptanez, Tuamine, Heptamine, 1-Methylhexylamine, 2-Heptylamine","CCCCCC(C)N",1.97,0,1,4]
["S4521","DEET","a3","L1300-18","in 10mM DMSO","NDC","Martindale the Extra Pharmacopoei, USP43-NF38, Ph.Int_6th, IP2010",null,"Others","Anti-infection","Microbiology","DEET (N,N-Diethyl-meta-toluamide, diethyltoluamide) is a commen active ingredient insect repellent.",191.27,"134-62-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/deet.html","C12H17NO","free base","N,N-Diethyl-meta-toluamide, diethyltoluamide","CCN(CC)C(=O)C1=CC(=CC=C1)C",2.427,1,0,3]
["S4522","Dehydroacetic acid","b3","L1300-18","in 10mM DMSO","DMF","Martindale the Extra Pharmacopoei, USP43-NF38, IP2010",null,"Others","Bacterial","Microbiology","Dehydroacetic acid (Biocide 470F, Methylacetopyronone) is an organic compound, used mostly as a fungicide and bactericide.",168.15,"520-45-6",33,196.25,"<1",0,"http://selleckchem.com/products/dehydroacetic-acid.html","C8H8O4","free base","Biocide 470F, Methylacetopyronone","CC(=O)C1C(=O)OC(=CC1=O)C",-0.014,4,0,1]
["S4524","2-Ethoxybenzamide","c3","L1300-18","in 10mM DMSO","CFDA, NDC, PMDA","KP Ⅹ, JP17",null,"Inflammation","Immunology & Inflammation related","Immunology & Inflammation","2-Ethoxybenzamide (Ethenzamide) is a common analgesic and anti-inflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains.",165.19,"938-73-8","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/2-ethoxybenzamide.html","C9H11NO2","Free Base","Ethenzamide","CCOC1=C(C=CC=C1)C(N)=O",1.164,2,1,3]
["S4525","Ethylparaben","d3","L1300-18","in 10mM DMSO","CFDA",null,null,"Others","Fungal","Microbiology","Ethylparaben (Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative and food additive. It is a standardized chemical allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.",166.17,"120-47-8",33,198.59,"<1",0,"http://selleckchem.com/products/ethylparaben.html","C9H10O3","free base","Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate","CCOC(=O)C1=CC=C(O)C=C1",1.792,2,1,3]
["S4526","Fenbufen","e3","L1300-18","in 10mM DMSO","DMF,CFDA","BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia",null,"Immunology/Inflammation/Neurological Disease","COX","Neuronal Signaling","Fenbufen (Lederfen, CL-82204) is an orally active phenylalkanoic derivative with anti-inflammatory, analgesic and antipyretic activity. It is a non-steroidal anti-inflammatory drug.",254.28,"36330-85-5",50,196.63,"<1",0,"http://selleckchem.com/products/fenbufen.html","C16H14O3","free base","Lederfen, CL-82204","OC(=O)CCC(=O)C1=CC=C(C=C1)C2=CC=CC=C2",2.933,2,0,5]
["S4527","Fenofibric acid","f3","L1300-18","in 10mM DMSO","FDA,NDC,DMF",null,"200264,200750,200913,200920,201573,208705","Cardiovascular Disease","PPAR","Metabolism","Fenofibric acid (NSC 281318, Trilipix, FNF acid) is a fibrate that acts as a lipid-lowering agent, decreasing low-density lipoprotein cholesterol and triglycerides.",318.75,"42017-89-0",63,197.65,63,197.65,"http://selleckchem.com/products/fenofibric-acid.html","C17H15ClO4","free base","NSC 281318, Trilipix, FNF acid","CC(C)(OC1=CC=C(C=C1)C(=O)C2=CC=C(Cl)C=C2)C(O)=O",4.159,3,0,5]
["S4528","Furazolidone","g3","L1300-18","in 10mM DMSO","FDA,CFDA,DMF","USP42-NF37;BP2019;IP2010;Martindale:The Extra Pharmacopoeia","011270,011323","Gastroenterology/Infection","Bacterial","Microbiology","Furazolidone(Furoxone) is a synthetic nitrofuran derivative with bactericidal or bacteriostatic activity when used against Gram-positive and Gram-negative bacteria.",225.16,"67-45-8",45,199.86,"<1",0,"http://selleckchem.com/products/furazolidone.html","C8H7N3O5","free base","Furoxone","[O-][N+](=O)C1=CC=C(O1)\\C=N\\N2CCOC2=O",1.1,4,0,3]
["S4530","i-Inositol","h3","L1300-18","in 10mM DMSO","DMF, CFDA","EP10.4",null,"Nutritional support","Others","Others","i-Inositol, also known as myo-inositol, is a chemical compound which is sugar alcohol. i-Inositol is involved in a number of biological processes including insulin signal transduction, cytoskeleton transduction and so on.",180.16,"87-89-8",36,199.82,36,199.82,"http://selleckchem.com/products/i-inositol.html","C6H12O6","free base","myo-inositol","OC1C(O)C(O)C(O)C(O)C1O",-3.065,0,6,0]
["S4532","Iopamidol","a4","L1300-18","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","074629,074734","Diagnosis","Others","Others","Iopamidol (Iopamiro, Isovue, Iopamiron, Niopam, Solutrast,B-15000,SQ-13396) is a non-ionic, water-soluble radiographic contrast agent.",777.09,"60166-93-0",100,128.69,100,128.69,"http://selleckchem.com/products/iopamidol.html","C17H22I3N3O8","free base","Iopamiro, Isovue, Iopamiron, Niopam, Solutrast,B-15000,SQ-13396","CC(O)C(=O)NC1=C(I)C(=C(I)C(=C1I)C(=O)NC(CO)CO)C(=O)NC(CO)CO",-1.187,3,8,10]
["S4534","6-Acetamidohexanoic acid","b4","L1300-18","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Others","Others","Others","6-Acetamidohexanoic acid (6-Acetamidocaproic acid) is a pharmaceutical intermediate.",173.21,"57-08-9","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/6-acetamidohexanoic-acid.html","C8H15NO3","Free Base","6-Acetamidocaproic acid","CC(=O)NCCCCCC(O)=O",0.337,2,1,6]
["S4535","Methylene Blue","c4","L1300-18","in 10mM DMSO","FDA,NDC,DMF",null,"204630","Metabolic Disease","Dyes,Guanylate Cyclase,Microtubule Associated","GPCR & G Protein","Methylene Blue (Basic Blue 9, Tetramethylthionine chloride, methylthioninium chloride, CI-52015) is used as a dye in chromoendoscopy. It Inhibits tau filament formation with IC50 of 1.9μM. Also it inhibits soluble guanylyl cyclase.",319.85,"61-73-4",63,196.97,63,196.97,"http://selleckchem.com/products/methylene-blue.html","C16H18ClN3S","free base","Basic Blue 9, Tetramethylthionine chloride, methylthioninium chloride, CI-52015","[Cl-].CN(C)C1=CC2=C(C=C1)N=C3C=CC(C=C3S2)=[N+](C)C",0.369,1,0,1]
["S4536","Nitrofurantoin","d4","L1300-18","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","073652,073671,073696,074336,074967,077025,080003,080043,080078,080447,084085,084326,085796,085797,091095,201355,201679,201693,201722,203233,205005,205180","Infection","Antibiotics,Bacterial","Microbiology","Nitrofurantoin (Macrodantin, Furadantine, Furadonine) is an antibiotic used to treat bladder infections.It inhibits bacterial DNA, RNA, and cell wall protein synthesis.",238.16,"67-20-9",47,197.35,"<1",0,"http://selleckchem.com/products/nitrofurantoin.html","C8H6N4O5","free base","Macrodantin, Furadantine, Furadonine","[O-][N+](=O)C1=CC=C(O1)/C=N/N2CC(=O)NC2=O",0.105,4,1,3]
["S4538","Pantoprazole sodium","e4","L1300-18","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.6;IP2010;CP2005;Martindale:The Extra Pharmacopoeia","022226,077056,077058,077619,078281,079197,090074,090296,090797,090807,090901,090970,091231,200794,200821,202038,202052,202882,203024,204400,205119,205675,208580,209463,209524,211368","Gastroenterology","ATPase,Proton Pump","Transmembrane Transporters","Pantoprazole (SKF96022, BY-1023) is a proton pump inhibitor drug that inhibits gastric acid secretion. It works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid.",405.35,"138786-67-1",81,199.83,81,199.83,"http://selleckchem.com/products/pantoprazole-sodium.html","C16H14F2N3NaO4S","Free Base","SKF96022 sodium, BY-1023 sodium","[Na+].COC1=CC=NC(=C1OC)C[S](=O)C2=NC3=C([N-]2)C=CC(=C3)OC(F)F",2.883,6,0,7]
["S4539","Salicylic acid","f4","L1300-18","in 10mM DMSO","DMF,CFDA,NDC,PMDA,HMA",null,null,"Others","COX","Neuronal Signaling","Salicylic acid (2-Hydroxybenzoic acid) is a beta hydroxy acid that occurs as a natural compound in plants which is an inhibitor of ethylene biosynthesis and cyclooxygenase activity.",138.12,"69-72-7",27,195.48,"<1",0,"http://selleckchem.com/products/salicylic-acid.html","C7H6O3","free base","2-Hydroxybenzoic acid","OC(=O)C1=C(O)C=CC=C1",1.217,1,1,1]
["S4541","Triclosan","g4","L1300-18","in 10mM DMSO","FDA,NDC,DMF","USP42-NF37;KP Ⅹ;Martindale:The Extra Pharmacopoeia","020231","Others","Bacterial","Microbiology","Triclosan (Irgasan, Cloxifenolum) is a diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.",289.54,"3380-34-5",57,196.86,"<1",0,"http://selleckchem.com/products/triclosan.html","C12H7Cl3O2","free base","Irgasan, Cloxifenolum","OC1=CC(=CC=C1OC2=CC=C(Cl)C=C2Cl)Cl",5.141,1,1,2]
["S4542","Trihexyphenidyl hydrochloride","h4","L1300-18","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA",null,"040177,040184,040251,040254,040337,084363,084364,085105,085117,085622,088035,089514,091630","Neurological Disease","AChR","Neuronal Signaling","Trihexyphenidyl hydrochloride (Benzhexol, Artane) is an antiparkinsonian agent of the antimuscarinic class.",337.93,"52-49-3",7,20.71,"<1",0,"http://selleckchem.com/products/trihexyphenidyl-hydrochloride.html","C20H31NO.HCl","hydrochloride","Benzhexol hydrochloride, Artane hydrochloride","Cl.OC(CCN1CCCCC1)(C2CCCCC2)C3=CC=CC=C3",4.799,0,0,5]
["S4543","Trimetazidine dihydrochloride","a5","L1300-18","in 10mM DMSO","DMF,CFDA,PMDA,HMA","BP2019;KP Ⅹ;EP9.2;IP2010;JP17;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","FAO","Metabolism","Trimetazidine dihydrochloride (Yoshimilon, Kyurinett, Vastarel F) is a kind of drug for treatment of chronic ischemic disorders. It improves myocardial glucose utilization through inhibition of fatty acid metabolism, known as fatty acid oxidation inhibitor.",339.26,"13171-25-0",67,197.49,67,197.49,"http://selleckchem.com/products/trimetazidine-dihydrochloride.html","C14H22N2O3.2HCl","Dihydrochloride","Yoshimilon, Kyurinett, Vastarel F","Cl.Cl.COC1=C(OC)C(=C(CN2CCNCC2)C=C1)OC",2.039,3,1,5]
["S4544","Urethane","b5","L1300-18","in 10mM DMSO","DMF","USP42-NF37",null,"Others","Bacterial","Microbiology","Urethane (Carbamic acid ethyl ester, Ethyl carbamate, Ethylurethane) is a kind of antineoplastic agent that is also used as a veterinary anesthetic. It is a intermediate in organic synthesis.",89.09,"51-79-6",17,190.82,17,190.82,"http://selleckchem.com/products/urethane.html","C3H7NO2","free base","Carbamic acid ethyl ester, Ethyl carbamate, Ethylurethane","CCOC(N)=O",0.159,2,1,2]
["S4546","Xylitol","c5","L1300-18","in 10mM DMSO","DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia",null,"Others","Autophagy","Autophagy","Xylitol (Adonitol, Ribitol, Xylite, D-Xylitol, Adonite) is a sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener.",152.15,"87-99-0",30,197.17,30,197.17,"http://selleckchem.com/products/xylitol.html","C5H12O5","free base","Adonitol, Ribitol, Xylite, D-Xylitol, Adonite","OCC(O)C(O)C(O)CO",-2.43,0,5,4]
["S4547","8-Hydroxyquinoline","d5","L1300-18","in 10mM DMSO","DMF","USP42-NF37;BP2019;IP2010",null,"Parasite","Bacterial","Microbiology","8-Hydroxyquinoline (8-Oxychinolin, 8-Quinolinol, Oxine) is an antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes.",145.16,"148-24-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/8-hydroxyquinoline.html","C9H7NO","Free Base","8-Oxychinolin, 8-Quinolinol, Oxine","OC1=CC=CC2=CC=CN=C12",1.774,1,1,0]
["S4548","Aminoguanidine hydrochloride","e5","L1300-18","in 10mM DMSO","DMF","USP42-NF37",null,"Endocrinology/Metabolic Disease","NOS","Immunology & Inflammation","Aminoguanidine (Pimagedine, Guanyl hydrazine, Hydrazinecarboximidamide, Imino semicarbazide, Monoaminoguanidine) is a diamine oxidase and nitric oxide synthase inhibitor. It acts to reduce levels of advanced glycation end products (AGEs) through interacting with 3-deoxyglucosone.",110.55,"1937-19-5",22,199,22,199,"http://selleckchem.com/products/aminoguanidine-hydrochloride.html","CH6N4.HCl","hydrochloride","Pimagedine, Guanyl hydrazine, Hydrazinecarboximidamide, Imino semicarbazide, Monoaminoguanidine","Cl.NNC(N)=N",-1.098,0,3,1]
["S4550","Azelaic acid","f5","L1300-18","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA",null,"204637,208011,208724,210928,211077","Inflammation","Bacterial","Microbiology","Azelaic acid (Nonanedioic acid, Finacea, Azelex, Anchoic acid) is an organic compound produced by the ozonolysis of oleic acid and possesses antibacterial, keratolytic, comedolytic, and anti-oxidant activity.",188.22,"123-99-9",37,196.58,37,196.58,"http://selleckchem.com/products/azelaic-acid.html","C9H16O4","free base","Nonanedioic acid, Finacea, Azelex, Anchoic acid","OC(=O)CCCCCCCC(O)=O",1.921,2,0,8]
["S4552","Bithionol","g5","L1300-18","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Parasite","cAMP","GPCR & G Protein","Bithionol (Actamer) is a potent inhibitor of soluble adenylyl cyclase(sAC) with an IC50 of 4 μM and has antibacterial and anthelmintic properties along with algaecide activity.",356.05,"97-18-7",71,199.41,"<1",0,"http://selleckchem.com/products/bithionol.html","C12H6Cl4O2S","free base","Actamer","OC1=C(Cl)C=C(Cl)C=C1SC2=C(O)C(=CC(=C2)Cl)Cl",6.122,0,2,2]
["S4553","Bronopol","h5","L1300-18","in 10mM DMSO","DMF","BP2019;Martindale:The Extra Pharmacopoeia",null,"Infection","Bacterial","Microbiology","Bronopol (2-bromo-2-nitropropane-1,3-diol) is antibacterial agent, used as preservative in cosmetic industry.",199.99,"52-51-7",39,195.01,39,195.01,"http://selleckchem.com/products/bronopol.html","C3H6BrNO4","free base","N/A","OCC(Br)(CO)[N+]([O-])=O",0.056,0,2,3]
["S4556","Carzenide","a6","L1300-18","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Carzenide (4-Sulfamoylbenzoic acid) is an organic synthesis intermediate, used for synthetic drug.",201.2,"138-41-0",40,198.81,"<1",0,"http://selleckchem.com/products/carzenide.html","C7H7NO4S","free base","4-Sulfamoylbenzoic acid","N[S](=O)(=O)C1=CC=C(C=C1)C(O)=O",0.164,3,1,2]
["S4558","Citiolone","b6","L1300-18","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Others","Others","Citiolone is a derivative of the amino acid cysteine, used in liver therapy.",159.21,"1195-16-0",31,194.71,31,194.71,"http://selleckchem.com/products/citiolone.html","C6H9NO2S","free base","N/A","CC(=O)NC1CCSC1=O",-0.345,2,1,1]
["S4559","Cloxiquine","c6","L1300-18","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","Fungal","Microbiology","Cloxiquine (5-Chloro-8-quinolinol, Dermofungin) is an antibacterial, antifungal, antiaging and antituberculosis drug.",179.6,"130-16-5",35,194.88,"<1",0,"http://selleckchem.com/products/cloxiquine.html","C9H6ClNO","free base","5-Chloro-8-quinolinol, Dermofungin","OC1=CC=C(Cl)C2=CC=CN=C12",2.438,1,1,0]
["S4561","Danthron","d6","L1300-18","in 10mM DMSO","marketed in South Africa",null,null,"Inflammation","AMPK","PI3K/Akt/mTOR","Danthron (Chrysazin, Antrapurol) functions in regulating glucose and lipid metabolism by activating AMPK. Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron used to be a laxativa and now is currently used as an antioxidant in synthetic lubricants, in the synthesis of experimental antitumor agents, as a fungicide and as an intermediate for making dyes.",240.21,"117-10-2",4,16.65,"<1",0,"http://selleckchem.com/products/danthron.html","C14H8O4","free base","chrysazin, Antrapurol","OC1=CC=CC2=C1C(=O)C3=C(O)C=CC=C3C2=O",2.324,2,2,0]
["S4562","Dehydrocholic acid","e6","L1300-18","in 10mM DMSO","CFDA,PMDA",null,null,"Gastroenterology","Others","Others","Dehydrocholic acid (Decholin, Dehystolin, Felacrinos, Sanocholen) is a semisynthetic bile acid made from cholic acid. It is used as a cholagogue, hydrocholeretic, diuretic, and as a diagnostic aid.",402.52,"81-23-2",80,198.75,"<1",0,"http://selleckchem.com/products/dehydrocholic-acid.html","C24H34O5","free base","Decholin, Dehystolin, Felacrinos, Sanocholen","CC(CCC(O)=O)C1CCC2C3C(CC(=O)C12C)C4(C)CCC(=O)CC4CC3=O",2.784,4,0,4]
["S4563","Diatrizoic acid","f6","L1300-18","in 10mM DMSO","DMF,CFDA",null,null,"Diagnosis","Others","Others","Diatrizoic Acid (Amidotrizoic acid, Diatrizoate) is an organic, iodinated radiocontrast agent used in diagnostic radiography.",613.91,"117-96-4","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/diatrizoic-acid.html","C11H9I3N2O4","Free Base","Amidotrizoic acid, Diatrizoate","CC(=O)NC1=C(I)C(=C(I)C(=C1I)NC(C)=O)C(O)=O",1.435,3,2,3]
["S4564","Diethylcarbamazine citrate","g6","L1300-18","in 10mM DMSO","FDA,DMF,PMDA",null,"006459","Parasite","Parasite","Microbiology","Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria and is highly specific for several parasites and does not contain any toxic metallic elements.",391.42,"1642-54-2",78,199.27,78,199.27,"http://selleckchem.com/products/diethylcarbamazine-citrate.html","C10H21N3O.C6H8O7","citrate","N/A","CCN(CC)C(=O)N1CCN(C)CC1.OC(=O)CC(O)(CC(O)=O)C(O)=O",-3.918,4,0,7]
["S4565","Diiodohydroxyquinoline","h6","L1300-18","in 10mM DMSO","CFDA","IP2010;Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","Bacterial","Microbiology","Diiodohydroxyquinoline (Iodoquinol) is a topical therapeutic agent,a quinoline derivative, with satisfactory antibacterial properties.",396.95,"83-73-8",13,32.75,"<1",0,"http://selleckchem.com/products/diiodohydroxyquinoline.html","C9H5I2NO","free base","Iodoquinol","OC1=C(I)C=C(I)C2=CC=CN=C12",2.93,1,1,0]
["S4566","DL-Panthenol","a7","L1300-18","in 10mM DMSO","NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","DL-panthenol (DL-Pantothenol, DL-Pantothenyl alcohol) is a racemic mixture of D and L form of panthenol,a provitamin of B5.",205.25,"16485-10-2",41,199.76,41,199.76,"http://selleckchem.com/products/dl-panthenol.html","C9H19NO4","free base","DL-Pantothenol, DL-Pantothenyl alcohol","CC(C)(CO)C(O)C(=O)NCCCO",-1.266,1,4,6]
["S4568","Ethylvanillin","b7","L1300-18","in 10mM DMSO",null,"USP43-NF38",null,"Others","Others","Others","Ethylvanillin (Ethylprotal, Bourbonal, Rhodiarome) is the organic flavorant. It is about three times as potent as vanillin and used in the production of chocolate.",166.17,"121-32-4",33,198.59,2,12.04,"http://www.selleckchem.com/products/ethylvanillin.html","C9H10O3","Free Base","Ethylprotal, Bourbonal, Rhodiarome","CCOC1=C(O)C=CC(=C1)C=O",1.679,2,1,3]
["S4569","Fluphenazine dihydrochloride","c7","L1300-18","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;IP2010;JP16;Martindale:The Extra Pharmacopoeia","070762","Psychotic disorders","Dopamine Receptor","GPCR & G Protein","Fluphenazine dihydrochloride (Prolixin) is a phenothiazine-class D1DR and D2DR inhibitor. It also inhibits  Histamine H1 Receptor.",510.44,"146-56-5",100,195.91,100,195.91,"http://selleckchem.com/products/fluphenazine-dihydrochloride.html","C22H26F3N3OS.2HCl","dihydrochloride","Prolixin","Cl.Cl.OCCN1CCN(CCCN2C3=C(SC4=CC=C(C=C24)C(F)(F)F)C=CC=C3)CC1",5.199,0,1,7]
["S4570","Halothane","d7","L1300-18","in 10mM DMSO","FDA,DMF,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","080810,083254,084977","Neurological Disease","Others","Others","Halothane (Narcotane) is a general inhalation anesthetic used for induction and maintenance of general anesthesia.",197.38,"151-67-7","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/halothane.html","C2HBrClF3","free base","Narcotane","FC(F)(F)C(Cl)Br",2.509,0,0,1]
["S4571","Hexylresorcinol","e7","L1300-18","in 10mM DMSO","NDC","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Infection","Tyrosinase","Proteases","Hexylresorcinol (4-Hexylresorcinol) is an organic compound with local anaesthetic, antiseptic and anthelmintic properties, is a potent inhibitor of mushroom tyrosinase. The IC50 values of hexylresorcinol for monophenolase is 1.24 μM and for diphenolase is 0.85 μM.",194.27,"136-77-6",38,195.6,"<1",0,"http://selleckchem.com/products/hexylresorcinol.html","C12H18O2","free base","4-Hexylresorcinol","CCCCCCC1=C(O)C=C(O)C=C1",4.113,0,2,5]
["S4576","Sulfabenzamide","f7","L1300-18","in 10mM DMSO","FDA,DMF","USP42-NF37;Martindale:The Extra Pharmacopoeia","088607,005794,086424,087285,087864,088462,088463,087887,088821","Infection","Bacterial","Microbiology","Sulfabenzamide (Sultrin, N-Sulfanilylbenzamide) is an antibacterial/antimicrobial which also exhibit their antitumor effects through multiple mechanisms including inhibition of membrane bound carbonic anhydrases, prevention of microtubule assembly, cell cycle arrest, and inhibition of angiogenesis.",276.31,"127-71-9",55,199.05,"<1",0,"http://selleckchem.com/products/sulfabenzamide.html","C13H12N2O3S","free base","Sultrin, N-Sulfanilylbenzamide","NC1=CC=C(C=C1)[S](=O)(=O)NC(=O)C2=CC=CC=C2",1.442,3,2,3]
["S4577","Terpin hydrate","g7","L1300-18","in 10mM DMSO","DMF","USP42-NF37;EP9.7;Martindale:The Extra Pharmacopoeia",null,"Respiratory Disease","Others","Others","Terpin hydrate is an expectorant, commonly used to loosen mucus in patients presenting with acute or chronic bronchitis, and related conditions.",190.28,"2451-01-6",38,199.71,"<1",0,"http://selleckchem.com/products/terpin-hydrate.html","C10H20O2.H2O","free base","N/A","O.CC(C)(O)C1CCC(C)(O)CC1",1.174,0,0,1]
["S4578","Tyloxapol","h7","L1300-18","in 10mM DMSO","FDA,DMF,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","020044","Respiratory Disease","Others","Others","Tyloxapol (Triton WR1339) is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surfactant to aid liquefaction, removal of mucopurulent and bronchopulmonary secretions. It also blocks plasma lipolytic activity, and thus the breakdown of triglyceride-rich lipoproteins.",0,"25301-02-4","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/tyloxapol.html","(C14H22O.C2H4O.CH2O)x","free base","Triton WR1339","CC1=CC(=CC(=C1OCCO)CC2=C(OCCO)C(=CC(=C2)C(C)(C)CC(C)(C)C)CC3=C(OCCO)C=CC(=C3)C(C)(C)CC(C)(C)C)C(C)(C)CC(C)(C)C",16.58,3,3,22]
["S4581","Triacetin","a8","L1300-18","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010",null,"Others","Fungal","Microbiology","Triacetin (Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane) is a triglyceride that is used as an antifungal agent.",218.2,"102-76-1","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/triacetin.html","C9H14O6","free base","Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane","CC(=O)OCC(COC(C)=O)OC(C)=O",-0.271,6,0,8]
["S4583","Butamben","b8","L1300-18","in 10mM DMSO","DMF,NDC","USP42-NF37",null,"Neurological Disease","Potassium Channel","Transmembrane Transporters","Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.",193.24,"94-25-7",38,196.65,38,196.65,"http://selleckchem.com/products/butamben.html","C11H15NO2","free base","Butyl 4-aminobenzoate","CCCCOC(=O)C1=CC=C(N)C=C1",2.267,2,1,5]
["S4584","Butylparaben","c8","L1300-18","in 10mM DMSO",null,"USP42-NF37;KP Ⅹ;BP2015;IP2010",null,"Others","Fungal","Microbiology","Butylparaben (Butyl parahydroxybenzoate, Butyl 4-hydroxybenzoate) is a chemical compound commonly used as an antifungal preservative in cosmetic products.",194.23,"94-26-8",38,195.64,38,195.64,"http://selleckchem.com/products/butylparaben.html","C11H14O3","free base","Butyl parahydroxybenzoate, Butyl paraben, Butyl 4-hydroxybenzoate","CCCCOC(=O)C1=CC=C(O)C=C1",2.772,2,1,5]
["S4585","Succinylsulfathiazole","d8","L1300-18","in 10mM DMSO",null,"EP7.5;BP2009;Martindale:The Extra Pharmacopoeia",null,"Infection","Antibiotics","Microbiology","Succinylsulfathiazole (Succinylsulphathiazole), a sulfonamide, is an antibiotic.",355.39,"116-43-8",71,199.78,"<1",0,"http://selleckchem.com/products/succinylsulfathiazole.html","C13H13N3O5S2","free base","Succinylsulphathiazole","OC(=O)CCC(=O)NC1=CC=C(C=C1)[S](=O)(=O)NC2=NC=CS2",0.28,5,2,7]
["S4587","Pentylenetetrazol","e8","L1300-18","in 10mM DMSO","marketed in Italy",null,null,"Neurological Disease","GABA Receptor","Neuronal Signaling","Pentylenetetrazol (Pentylenetetrazole, Metrazole, pentetrazol, pentamethylenetetrazol, Corazol, Cardiazol, PTZ) displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GABA(A) receptor antagonist.",138.17,"54-95-5",27,195.41,27,195.41,"http://selleckchem.com/products/pentylenetetrazol.html","C6H10N4","Free Base","Pentylenetetrazole, Metrazole, pentetrazol, pentamethylenetetrazol, Corazol, Cardiazol, PTZ","C1CC[N]2N=NN=C2CC1",0.568,3,0,0]
["S4588","Docusate Sodium","f8","L1300-18","in 10mM DMSO","CFDA,NDC","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017,USP39-NF34,IP2010",null,"Gastroenterology","Opioid Receptor","Neuronal Signaling","Docusate Sodium (Aerosol OT, Bis(2-ethylhexyl) sulfosuccinate sodium salt, Constonate) is a laxative used to treat constipation, for constipation due to the use of opiates it maybe used with a stimulant laxative, can be taken by mouth or rectally.",444.56,"577-11-7",88,197.95,18,40.49,"http://selleckchem.com/products/docusate-sodium.html","C20H37O7S.Na","sodium salt","Aerosol OT, Bis(2-ethylhexyl) sulfosuccinate sodium salt, Constonate","[Na+].CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)[S]([O-])(=O)=O",3.172,4,0,18]
["S4589","Amodiaquine dihydrochloride dihydrate","g8","L1300-18","in 10mM DMSO","FDA,CFDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,Ph.Int_6th,IP2010","006441","Infection/Parasitology","Histone Methyltransferase,HNMT,Transferase","Epigenetics","Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase with estimated Ki of 18.6 nM. It is also used as an antimalarial and anti-inflammatory agent.",464.81,"6398-98-7",92,197.93,29,62.39,"http://selleckchem.com/products/amodiaquine-dihydrochloride-dihydrate.html","C20H22ClN3O.2HCl.2H2O","dihydrochloride dihydrate","N/A","O.O.Cl.Cl.CCN(CC)CC1=CC(=CC=C1O)NC2=C3C=CC(=CC3=NC=C2)Cl",5.109,1,2,6]
["S4590","Dithranol","h8","L1300-18","in 10mM DMSO","CFDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.2,Ph.Int_6th,BP2017,IP2010",null,"Immunology","Others","Others","Dithranol (Anthralin, cignoline, 1,8,9-trihydroxyanthracene) is one of the most important local therapeutic agents against the common skin disease, psoriasis.",226.23,"1143-38-0",7,30.94,0,0,"http://selleckchem.com/products/dithranol.html","C14H10O3","free base","Anthralin, cignoline, 1,8,9-trihydroxyanthracene","OC1=CC=CC2=C1C(=O)C3=C(C2)C=CC=C3O",2.894,1,2,0]
["S4591","Nitroxoline","a9","L1300-18","in 10mM DMSO","marketed in Europe","Martindale:The Extra Pharmacopoeia",null,"Infection","Cathepsin B,Cysteine Protease","Proteases","Nitroxoline (8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol, 5-Nitro-8-hydroxyquinoline) is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. Nitroxoline impairs tumor progression in vitro and in vivo by inhibiting cathepsin B activity.",190.16,"4008-48-4",38,199.83,"<1",0,"http://selleckchem.com/products/nitroxoline.html","C9H6N2O3","free base","8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol, 5-Nitro-8-hydroxyquinoline","OC1=CC=C(C2=CC=CN=C12)[N+]([O-])=O",1.668,1,1,1]
["S4593","Chlormadinone acetate","b9","L1300-18","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,JP17,BP2017",null,"Cancer/Endocrinology","5-alpha Reductase,Androgen Receptor","Endocrinology & Hormones","Chlormadinone acetate (Gestafortin) is a steroidal progestin with additional antiandrogen and antigonadotropic effects, used often in combinations as an oral contraceptive. Its half-life is about 34-38 hours.",404.93,"302-22-7",27,66.68,"<1",0,"http://selleckchem.com/products/chlormadinone-acetate.html","C23H29ClO4","free base","Gestafortin","CC(=O)OC1(CCC2C3C=C(Cl)C4=CC(=O)CCC4(C)C3CCC12C)C(C)=O",3.428,4,0,3]
["S4594","Cephalothin sodium","c9","L1300-18","in 10mM DMSO","FDA,DMF","USP42-NF37","062426","Infection","Antibiotics,Antibiotics for Mammalian Cell Culture,Bacterial","Microbiology","Cephalothin (Cefalotin, Cephalotin) sodium is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.",418.42,"58-71-9",10,23.9,83,198.37,"http://selleckchem.com/products/cephalothin.html","C16H15N2NaO6S2","sodium","Cefalotin sodium, Sodium cephalotin","[Na+].CC(=O)OCC1=C(N2C(SC1)C(NC(=O)CC3=CC=CS3)C2=O)C([O-])=O",-1.067,4,1,7]
["S4595","Cefazolin Sodium","d9","L1300-18","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,EP9.7,KP Ⅹ,JP17,BP2017","062688,062807,062831,062894,062988,062989,063016,063018,063207,063208,063209,063214,063216,064033,064169,064170,065047,065141,065143,065226,065244,065247,065280,065295,065296,065303,065306,065345,065395,201654,203661,209217","Infection","Antibiotics,Bacterial","Microbiology","Cefazolin Sodium (cefazoline, cephazolin, Ancef) is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.",476.49,"27164-46-1",95,199.37,95,199.37,"http://selleckchem.com/products/cefazolin-sodium.html","C14H14N8O4S3.Na","sodium","cefazoline sodium, cephazolin sodium, Ancef","[Na+].CC1=NN=C(SCC2=C(N3C(SC2)C(NC(=O)C[N]4C=NN=N4)C3=O)C([O-])=O)S1",-2.807,7,1,7]
["S4596","Cefixime","e9","L1300-18","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,KP Ⅹ,JP17,BP2017","204835,206144,206938,206939,210574","Infection","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Bacterial","Microbiology","Cefixime (Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635) is an antibiotic useful for the treatment of a number of bacterial infections. It is a third generation cephalosporin.",453.45,"79350-37-1",90,198.48,"<1",0,"http://selleckchem.com/products/cefixime.html","C16H15N5O7S2","free base","Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635","NC1=NC(=CS1)C(=N/OCC(O)=O)/C(=O)NC2C3SCC(=C(N3C2=O)C(O)=O)C=C",-0.651,7,2,8]
["S4597","Lercanidipine hydrochloride","f9","L1300-18","in 10mM DMSO","CFDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Lercanidipine is a calcium channel blocker of the dihydropyridine class.",648.19,"132866-11-6",66,101.82,"<1",0,"http://selleckchem.com/products/lercanidipine-hydrochloride.html","C36H41N3O6.HCl","hydrochloride","Zanidip (hydrochloride), Masnidipine (hydrochloride)","Cl.COC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OC(C)(C)CN(C)CCC(C3=CC=CC=C3)C4=CC=CC=C4)C",6.514,4,1,14]
["S4599","Benzyl benzoate","g9","L1300-18","in 10mM DMSO","FDA,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017","084535","Parasite","Parasite","Microbiology","Benzyl benzoate (Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester) is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.",212.24,"120-51-4","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/benzyl-benzoate.html","C14H12O2","free base","Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester","O=C(OCC1=CC=CC=C1)C2=CC=CC=C2",3.268,2,0,4]
["S4600","Benzyl alcohol","h9","L1300-18","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,EP9.4,KP Ⅹ,Ph.Int_6th,JP17,BP2017,USP39-NF34","022129","Parasite","Others","Others","Benzyl alcohol (Phenylmethanol, Benzenemethanol, Phenylcarbinol, Benzoyl alcohol) is used as a local anesthetic. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.",108.14,"100-51-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/benzyl-alcohol.html","C7H8O","free base","Phenylmethanol, Benzenemethanol, Phenylcarbinol, Benzoyl alcohol","OCC1=CC=CC=C1",1.225,0,1,1]
["S4601","Clioquinol","a10","L1300-18","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.,BP2017","050235","Infection","Fungal","Microbiology","Clioquinol is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.",305.5,"130-26-7",61,199.67,"<1",0,"http://selleckchem.com/products/5-chloro-8-hydroxy-7-iodoquinoline.html","C9H5ClINO","free base","Iodochlorhydroxyquin, Chinoform","OC1=C(I)C=C(Cl)C2=CC=CN=C12",3.016,1,1,0]
["S4602","Acetohydroxamic acid","b10","L1300-18","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","018749","Infection","Bacterial","Microbiology","Acetohydroxamic acid (N-Hydroxyacetamide, Methylhydroxamic acid, Acetic acid|oxime, Lithostat,AHA) is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.",75.07,"546-88-3",15,199.81,15,199.81,"http://selleckchem.com/products/acetohydroxamic-acid.html","C2H5NO2","free base","N-Hydroxyacetamide, Methylhydroxamic acid, Acetic acid|oxime, Lithostat,AHA","CC(=O)NO",-0.82,1,1,0]
["S4603","Gallic acid","c10","L1300-18","in 10mM DMSO","NDC","EP9.1,BP2019",null,"Cancer/Infection","ROS","Immunology & Inflammation","Gallic acid (3,4,5-Trihydroxybenzoic acid, Gallate, Benzoic acid), known as powerful antioxidants, is an organic acid found in a variety of foods and herbs.",170.12,"149-91-7",34,199.86,7,41.15,"http://selleckchem.com/products/gallic-acid.html","C7H6O5","free base","3,4,5-Trihydroxybenzoic acid, Gallate, Benzoic acid","OC(=O)C1=CC(=C(O)C(=C1)O)O",0.733,1,3,1]
["S4604","Levofloxacin hydrate","d10","L1300-18","in 10mM DMSO","PMDA","JP17",null,"Infection","Topoisomerase","DNA Damage/DNA Repair","Levofloxacin (Levaquin, Tavanic, Quixin, Iquix, Cravit) is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. It acts by inhibiting DNA gyrase (bacterial topoisomerase II).",370.38,"138199-71-0",74,199.79,5,13.5,"http://selleckchem.com/products/levofloxacin-hydrate.html","C18H20FN3O4.1/2H2O","hydrate","Levofloxacin hemihydrate, Levaquin hydrate, Tavanic hydrate, Quixin hydrate, Iquix hydrate, Cravit hydrate","CC1COC2=C3N1C=C(C(O)=O)C(=O)C3=CC(=C2N4CCN(C)CC4)F",-0.64,3,0,2]
["S4607","2,2′-Dihydroxy-4-methoxybenzophenone","e10","L1300-18","in 10mM DMSO",null,"USP43-NF38",null,"Others","Others","Others","2,2′-Dihydroxy-4-methoxybenzophenone (Dioxybenzone, Dioxybenzon, Advastab 47, Cyasorb UV 24, Benzophenone-8) is an organic compound used in sunscreen to block UVB and short-wave UVA (ultraviolet) rays.",244.24,"131-53-3",48,196.53,"<1",0,"http://selleckchem.com/products/2-2-dihydroxy-4-methoxybenzophenone.html","C14H12O4","free base","Dioxybenzone, Dioxybenzon, Advastab 47, Cyasorb UV 24, Benzophenone-8","COC1=CC(=C(C=C1)C(=O)C2=C(O)C=CC=C2)O",2.733,2,2,3]
["S4609","Diflunisal","f10","L1300-18","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP7.5,BP2015","073562,073563,073673,073679,074285,074400,074604,202845,203547","Immunology/Inflammation","COX","Neuronal Signaling","Diflunisal (Dolobid, Dolobis, Flovacil, Fluniget,MK-647) is a difluorophenyl derivate of salicylic acid and a nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic and anti-inflammatory properties. The mechanism of action of diflunisal is as a Cyclooxygenase Inhibitor.",250.2,"22494-42-4",50,199.84,"<1",0,"http://selleckchem.com/products/diflunisal.html","C13H8F2O3","free base","Dolobid, Dolobis, Flovacil, Fluniget,MK-647","OC(=O)C1=C(O)C=CC(=C1)C2=C(F)C=C(F)C=C2",3.147,1,1,2]
["S4610","Mebendazole","g10","L1300-18","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,Ph.Int_6th,BP2017,IP2010","073580,017481,208398","Infection/Parasitology","Parasite","Microbiology","Mebendazole (Vermox, Telmin, Pantelmin, Mebenvet) is a synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake.",295.29,"31431-39-7",6,20.32,"<1",0,"http://selleckchem.com/products/mebendazole.html","C16H13N3O3","free base","Vermox, Telmin, Pantelmin, Mebenvet","COC(=O)NC1=NC2=C([NH]1)C=CC(=C2)C(=O)C3=CC=CC=C3",3.055,4,2,4]
["S4612","Dapson","h10","L1300-18","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,Ph.Int_6th,BP2017,IP2010","086841,086842,203887,204074,204380,205429,206505,207165,209430,209506,210191","Immunology/Infection","Antibiotics","Microbiology","Dapson (Dapsone, 4,4′-Diaminodiphenyl sulfone, 4,4′-Sulfonyldianiline, 4-Aminophenyl sulfone, Bis(4-aminophenyl) sulfone, DDS), also known as diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy.",248.3,"80-08-0",49,197.34,"<1",0,"http://selleckchem.com/products/dapson.html","C12H12N2O2S","free base","Dapsone, 4,4′-Diaminodiphenyl sulfone, 4,4′-Sulfonyldianiline, 4-Aminophenyl sulfone, Bis(4-aminophenyl) sulfone, DDS","NC1=CC=C(C=C1)[S](=O)(=O)C2=CC=C(N)C=C2",1.439,2,2,2]
["S4618","Fenoldopam mesylate","a11","L1300-18","in 10mM DMSO","FDA,NDC,DMF","USP42-NF37","076582,076656,077155,077826","Cardiovascular Disease","Dopamine Receptor","Neuronal Signaling","Fenoldopam (SKF 82526, Corlopam) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.",401.86,"67227-57-0",80,199.07,"<1",0,"http://selleckchem.com/products/fenoldopam-mesylate.html","C16H16ClNO3.CH4O3S","mesylate","SKF 82526 (mesylate), Fenoldopam methanesulfonate, Corlopam mesylate","C[S](O)(=O)=O.OC1=CC=C(C=C1)C2CNCCC3=C(Cl)C(=C(O)C=C23)O",2.639,0,4,1]
["S4619","Itopride hydrochloride","b11","L1300-18","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Gastrointestinal Disease","AChR","Neuronal Signaling","Itopride hydrochloride (Ganaton, HSR803) is an AChE inhibitor. The IC50 of itopride with AChE is 2.04 +/- 0.27 μM.",394.89,"122892-31-3",78,197.52,78,197.52,"http://selleckchem.com/products/itopride-hydrochloride.html","C20H26N2O4.HCl","hydrochloride","Ganaton, HSR803","Cl.COC1=CC=C(C=C1OC)C(=O)NCC2=CC=C(OCCN(C)C)C=C2",3.093,4,1,9]
["S4620","Cefuroxime sodium","c11","L1300-18","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,EP7.0,BP2017，USP39-NF34,JP15,KP Ⅹ","064035,064036,064124,064125,064191,064192,065001,065002,065046,065048,065483,065484,065503","Infection","β-lactamase","Microbiology","Cefuroxime Sodium is a cephalosporin effective against gram-positive and gram-negative bacteria with resistance to β-lactamase.",446.37,"56238-63-2",89,199.39,89,199.39,"http://selleckchem.com/products/cefuroxime-sodium.html","C16H16N4O8S.Na","sodium","N/A","[Na+].CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)COC(N)=O)C3=CC=CO3",-1.877,7,2,8]
["S4622","3,4-Diaminopyridine","d11","L1300-18","in 10mM DMSO","DMF,EMA,NDC,FDA","Martindale the Extra Pharmacopoei",null,"Others","Others","Others","3,4-Diaminopyridine (Amifampridine, pyridine-3,4-diamine) blocks presynaptic potassium channels, and subsequently prolongs the action potential and increases presynaptic calcium concentrations. It is a drug predominantly used in the treatment of a number of rare muscle diseases.",109.13,"54-96-6",22,201.59,7,64.14,"http://www.selleck.cn/products/3-4-diaminopyridine.html","C5H7N3","free base","Amifampridine, pyridine-3,4-diamine","NC1=C(N)C=NC=C1",-0.814,1,2,0]
["S4623","Methylbenactyzine Bromide","e11","L1300-18","in 10mM DMSO","CFDA",null,null,"Others","AChR","Neuronal Signaling","Methylbenactyzine Bromide (Gastrimade, Noinarin, Paragone, Semulgin) is a kind of muscarinic cholinergic receptor antagonist with antispasmodic activity.",422.36,"3166-62-9",84,198.88,84,198.88,"http://selleckchem.com/products/methylbenactyzine-bromide.html","C21H28NO3.Br","bromide","Gastrimade, Noinarin, Paragone, Semulgin","[Br-].CC[N+](C)(CC)CCOC(=O)C(O)(C1=CC=CC=C1)C2=CC=CC=C2",-0.322,2,0,9]
["S4624","5,5-Dimethyloxazolidine-2,4-dione","f11","L1300-18","in 10mM DMSO","DMF",null,null,"Others","Others","Others","5,5-Dimethyloxazolidine-2,4-dione (Dimethadione, Dimethyloxazolidinedione, Dimethadion) is an anticonvulsant that is the active metabolite of trimethadione.",129.11,"695-53-4",84,650.61,84,650.61,"http://selleckchem.com/products/5-5-dimethyloxazolidine-2-4-dione.html","C5H7NO3","bromide","Dimethadione, Dimethyloxazolidinedione, Dimethadion","CC1(C)OC(=O)NC1=O",-0.322,2,0,9]
["S4625","Alcaftadine","g11","L1300-18","in 10mM DMSO","FDA,DMF,NDC",null,"022134","Immunology/Inflammation/Ophthalmology","Histamine Receptor","Neuronal Signaling","Alcaftadine (Lastacaft, R89674) is a high affinity ligand for the H1 receptor, with a pKi (8.5) that is comparable with that of other H1 antihistamines. Alcaftadine is also an antagonist for H2 and H4 receptors with no affinity for the H3 receptor.",307.39,"147084-10-4",28,91.09,"<1",0,"http://selleckchem.com/products/alcaftadine.html","C19H21N3O","free base","Lastacaft, R89674","CN1CCC(CC1)=C2C3=C(CC[N]4C(=CN=C24)C=O)C=CC=C3",2.831,2,0,1]
["S4626","Ethosuximide","h11","L1300-18","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","040253,040430,040506,040686,081306,200892,211928","Neurological Disease","Calcium Channel","Transmembrane Transporters","Ethosuximide(Zarontin) is a succinimide anticonvulsant, used mainly in absence seizures; A calcium channel blocker.",141.17,"77-67-8",28,198.34,28,198.34,"http://selleckchem.com/products/ethosuximide.html","C7H11NO2","free base","Zarontin","CCC1(C)CC(=O)NC1=O",0.543,2,1,1]
["S4628","(+/-)-Sulfinpyrazone","a2","L1300-19","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,BP2017,JP15","087665,087666,087667,087769,087770,088666,088933,088934","Hematology/Metabolic Disease","COX","Neuronal Signaling","Sulfinpyrazone (G-28315, NSC 75925) is one of the most studied platelet COX inhibitors, also a uricosuric agent that competitively inhibits uric acid reabsorption in kidney proximal tubules.",404.48,"57-96-5",80,197.78,"<1",0,"http://selleckchem.com/products/sulfinpyrazone.html","C23H20N2O3S","free base","G-28315, NSC 75925","O=C1C(CC[S](=O)C2=CC=CC=C2)C(=O)N(N1C3=CC=CC=C3)C4=CC=CC=C4",3.434,3,0,6]
["S4629","Chlorotrianisene","b2","L1300-19","in 10mM DMSO","FDA,CFDA,DMF","Martindale:The Extra Pharmacopoeia","084652","Cancer/Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Chlorotrianisene (tri-p-anisylchloroethylene, TACE, CTA) is a synthetic, non-steroidal estrogen. It is a selective estrogen receptor modulator.",380.86,"569-57-3",76,199.55,"<1",0,"http://selleckchem.com/products/chlorotrianisene.html","C23H21ClO3","free base","tri-p-anisylchloroethylene, tris(p-methoxyphenyl)chloroethylene, TACE, CTA","COC1=CC=C(C=C1)C(Cl)=C(C2=CC=C(OC)C=C2)C3=CC=C(OC)C=C3",5.614,3,0,6]
["S4630","Diazoxide","c2","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017,Ph.Int_5th,IP2010","071519,071908","Cardiovascular Disease/Endocrinology/Metabolic Disease","ADC Cytotoxin,Potassium Channel","Transmembrane Transporters","Diazoxide (Sch-6783, SRG-95213, Proglycem) is a well-known small molecule that activates KATP channels in the smooth muscle of blood vessels and pancreatic beta-cells by increasing membrane permeability to potassium ions.",230.67,"364-98-7",46,199.42,"<1",0,"http://selleckchem.com/products/diazoxide.html","C8H7ClN2O2S","free base","Sch-6783, SRG-95213, Proglycem","CC1=NC2=CC=C(Cl)C=C2[S](=O)(=O)N1",1.196,3,1,0]
["S4631","Prochlorperazine dimaleate salt","d2","L1300-19","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017,IP2010",null,"Gastroenterology/Neurological Disease/Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Prochlorperazine dimaleate (Prochlorperazin, Compazine, Capazine, Stemetil) is a dopamine (D2) receptor antagonist.",606.09,"84-02-6",74,122.09,"<1",0,"http://selleckchem.com/products/prochlorperazine.html","C20H24ClN3S.C8H8O8","dimaleate","Prochlorperazin, Compazine, Capazine, Stemetil","CN1CCN(CCCN2C3=C(SC4=C2C=C(Cl)C=C4)C=CC=C3)CC1.OC(=O)\\C=C/C(O)=O.OC(=O)\\C=C/C(O)=O",-1.295,4,0,8]
["S4633","Isosorbide Mononitrate","e2","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia","075037,075041,075147,075155,075166,075306,075361,075395,075448,075522,076813,090598,200270,200495,209684,210822,210918","Cardiovascular Disease","Others","Others","Isosorbide mononitrate (Elantan, Monoket, Mononit, Imdur, Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.",191.14,"16051-77-7",38,198.81,38,198.81,"http://selleckchem.com/products/isosorbide-mononitrate.html","C6H9NO6","Free Base","Isosorbide-5-mononitrate, Elantan, Monoket, Mononit, Imdur, Corangin","OC1COC2C(COC12)O[N+]([O-])=O",1.003,3,1,2]
["S4634","Sodium sulfadiazine","f2","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP39-NF34","004054","Infection","Bacterial","Microbiology","Sodium Sulfadiazine (Sulfadiazin-natrium) is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative.",272.26,"547-32-0",9,33.06,54,198.34,"http://selleckchem.com/products/sodium-sulfadiazine.html","C10H10N4O2S.Na","Sodium salt","Sulfadiazin-natrium","NC1=CC=C(C=C1)[S](=O)(=O)N([Na])C2=NC=CC=N2",0.417,4,1,3]
["S4635","Cyproheptadine hydrochloride sesquihydrate","g2","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","040537,040644,040668,085245,086165,086580,086678,086737,086808,086833,087001,087056,087129,087284,087405,087566,087685,087839,088205,088212,088232,088798,089021,089057,089199,091295,203191,204823,205087,206553,206676,207555,207783,208938,209108,209172,212423","Immunology","5-HT Receptor,SETD","Neuronal Signaling","Cyproheptadine hydrochloride (Periactin, Peritol) is non-selective 5HT2 antagonist with IC50 of 0.6 nM. Also a SETD7/9 inhibitor.",350.88,"41354-29-4",70,199.5,"<1",0,"https://www.selleckchem.com/products/cyproheptadine-hydrochloride-sesquihydrate.html","C21H21N.HCl.3/2H2O","hydrochloride sesquihydrate","Periactin hydrochloride, Peritol","O.O.O.Cl.Cl.CN1CCC(CC1)=C2C3=CC=CC=C3C=CC4=CC=CC=C24.CN5CCC(CC5)=C6C7=CC=CC=C7C=CC8=CC=CC=C68",5.478,0,0,0]
["S4636","Teneligliptin hydrobromide","h2","L1300-19","in 10mM DMSO","PMDA",null,null,"Endocrinology/Metabolic Disease","DPP","Proteases","Teneligliptin (Teneligliptin hydrobromide anhydrous) is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 values of approximately 1 nM.",628.86,"906093-29-6",100,159.02,100,159.02,"http://selleckchem.com/products/teneligliptin-hydrobromide.html","C22H30N6OS.5/2HBr","hydrobromide","Teneligliptin hydrobromide anhydrous","CC1=N[N](C2=CC=CC=C2)C(=C1)N3CCN(CC3)C4CNC(C4)C(=O)N5CCSC5",2.645,2,1,4]
["S4637","Prasugrel Hydrochloride","a3","L1300-19","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","205790,205888,205897,205913,205927,205987,206021","Hematology","P2 Receptor","Neuronal Signaling","Prasugrel hydrochloride (Prasugrel HCl, LY640315,PCR 4099 Hydrochloride)  is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.",409.9,"389574-19-0",46,112.22,"<1",0,"http://selleckchem.com/products/prasugrel-hydrochloride.html","C20H20FNO3S.HCl","hydrochloride","Prasugrel HCl, LY640315,PCR 4099 Hydrochloride","Cl.CC(=O)OC1=CC2=C(CCN(C2)C(C(=O)C3CC3)C4=C(F)C=CC=C4)S1",4.183,3,0,6]
["S4638","Desogestrel","b3","L1300-19","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","075256,076915,076916,077182,091234,202085,202296,206853,207067,209170,076455,077182","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Desogestrel (Cerazette, Desogen, Desogestrelum, Org-2969) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.",310.47,"54024-22-5",62,199.7,"<1",0,"http://selleckchem.com/products/desogestrel.html","C22H30O","free base","Cerazette, Desogen, Desogestrelum, Org-2969","CCC12CC(=C)C3C(CCC4=CCCCC34)C1CCC2(O)C#C",5.828,0,0,1]
["S4640","Lesinurad","c3","L1300-19","in 10mM DMSO","FDA,NDC,EMA",null,"207988","Metabolic Disease","OAT","Transmembrane Transporters","Lesinurad (RDEA-594) is a selective uric acid reabsorption inhibitor (SURI) under investigation for treatment of gout in combination with xanthine oxidase inhibitors. Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively.",404.28,"878672-00-5",80,197.88,"<1",0,"http://selleckchem.com/products/lesinurad.html","C17H14BrN3O2S","free base","RDEA 594, RDEA-594, RDEA594","OC(=O)CSC1=NN=C(Br)[N]1C2=C3C=CC=CC3=C(C=C2)C4CC4",4.257,3,0,5]
["S4641","Tedizolid Phosphate","d3","L1300-19","in 10mM DMSO","FDA,EMA,NDC,PMDA",null,"205435,205436","Infection","Antibiotics","Microbiology","Tedizolid (TR-701FA) is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.",450.32,"856867-55-5",22,48.85,"<1",0,"http://selleckchem.com/products/tedizolid-phosphate.html","C17H16FN6O6P","free base","TR-701FA","C[N]1N=NC(=N1)C2=NC=C(C=C2)C3=CC=C(C=C3F)N4CC(CO[P](O)(O)=O)OC4=O",1.712,7,0,6]
["S4646","Ciclesonide","e3","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017,IP2010","021658,022004,022124,202129","Immunology/Inflammation","COVID-19,Glucocorticoid Receptor","Endocrinology & Hormones","Ciclesonide (Alvesco, Omnaris, RPR251526, Zetonna) is a glucocorticoid used to treat obstructive airway diseases.",540.69,"126544-47-6",100,184.95,"<1",0,"http://selleckchem.com/products/ciclesonide.html","C32H44O7","free base","Alvesco, Omnaris, RPR251526, Zetonna","CC(C)C(=O)OCC(=O)C12OC(OC1CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC23C)C6CCCCC6",4.696,6,1,6]
["S4647","Cefmenoxime hydrochloride","f3","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,JP17","050571","Infection","Antibiotics,Bacterial","Microbiology","Cefmenoxime (SCE-1365), a potent inhibitor of Enterobacteriaceae, is a cephalosporin antibiotic that is administered intravenously or intramuscularly.",1059.58,"75738-58-8",70,66.06,"<1",0,"http://selleckchem.com/products/cefmenoxime-hydrochloride.html","C32H34N18O10S6.HCl","hydrochloride","Cefmenoxime hemihydrochloride, SCE-1365 hemihydrochloride","Cl.CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)CSC3=NN=N[N]3C)C4=CSC(=N4)N.CO\\N=C(/C(=O)NC5C6SCC(=C(N6C5=O)C(O)=O)CSC7=NN=N[N]7C)C8=CSC(=N8)N",-1.031,18,4,16]
["S4648","Dantrolene sodium hemiheptahydrate","g3","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,BP2017,USP39-NF34","017443,018264","Metabolic Disease","Calcium Channel","Transmembrane Transporters","Dantrolene sodium hemiheptahydrate (Dantrium) is a skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber.",399.29,"24868-20-0",14,35.06,"<1",0,"https://www.selleckchem.com/products/dantrolene-sodium-s4648.html","C14H9N4O5.7/2H2O.Na","Sodium salt hemiheptahydrate","Dantrolene sodium salt, Dantrium, Sodium dantrolene","CCC1CN2CCC1CC2C(O)C3=C4C=C(OC)C=CC4=NC=C3",3.124,2,1,4]
["S4649","Atipamezole hydrochloride","h3","L1300-19","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Adrenergic Receptor","GPCR & G Protein","Atipamezole (Antisedan, MPV1248) is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. Atipamezole hydrochloride is hydrochloride form of atipamezole.",248.75,"104075-48-1",12,48.24,21,84.42,"http://selleckchem.com/products/atipamezole-hydrochloride.html","C14H16N2.HCl","hydrochloride","Antisedan, MPV-1248 hydrochloride, MPV1248 hydrochloride, MPV 1248 hydrochloride","Cl.CCC1(CC2=C(C1)C=CC=C2)C3=C[NH]C=N3",3.531,1,1,2]
["S4650","Atipamezole","a4","L1300-19","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Adrenergic Receptor","GPCR & G Protein","Atipamezole (MPV-1248, MPV1248, Antisedan) is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug.",212.29,"104054-27-5",42,197.84,"<1",0,"http://selleckchem.com/products/atipamezole.html","C14H16N2","Free Base","MPV-1248, MPV1248, MPV 1248, Antisedan","CCC1(CC2=C(C1)C=CC=C2)C3=CN=C[NH]3",3.012,1,1,2]
["S4651","Etoricoxib","b4","L1300-19","in 10mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia",null,"Immunology/Inflammation","COX","Neuronal Signaling","Etoricoxib (Arcoxia, MK-663, MK-0663, Tauxib, Algix, Nucoxia) is a new COX-2 selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties.",358.84,"202409-33-4",71,197.86,"<1",0,"http://selleckchem.com/products/etoricoxib.html","C18H15ClN2O2S","free base","Arcoxia, MK-663, MK-0663, Tauxib, Algix, Nucoxia","CC1=NC=C(C=C1)C2=NC=C(Cl)C=C2C3=CC=C(C=C3)[S](C)(=O)=O",3.467,4,0,3]
["S4652","Sulisobenzone","c4","L1300-19","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37",null,"Others","Others","Others","Sulisobenzone (Benzophenone-4, Sungard) is an ingredient in some sunscreens which protects the skin from damage.",308.31,"4065-45-6",61,197.85,61,197.85,"http://selleckchem.com/products/sulisobenzone.html","C14H12O6S","free base","Benzophenone-4, Sungard","COC1=CC(=C(C=C1[S](O)(=O)=O)C(=O)C2=CC=CC=C2)O",2.308,2,1,4]
["S4655","Sulpiride","d4","L1300-19","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.2,JP17",null,"Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Sulpiride (Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil) is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.",341.43,"15676-16-1",68,199.16,"<1",0,"http://selleckchem.com/products/sulpiride.html","C15H23N3O4S","free base","Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil","CCN1CCCC1CNC(=O)C2=C(OC)C=CC(=C2)[S](N)(=O)=O",0.704,4,2,6]
["S4656","Parecoxib","e4","L1300-19","in 10mM DMSO","DMF,EMA,CFDA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","COX","Neuronal Signaling","Parecoxib (SC-69124, Valus-P, Vorth-P) is a selective COX2 inhibitor.",370.42,"198470-84-7",74,199.77,"<1",0,"http://selleckchem.com/products/parecoxib.html","C19H18N2O4S","free base","SC-69124, Valus-P, Vorth-P","CCC(=O)N[S](=O)(=O)C1=CC=C(C=C1)C2=C(C)ON=C2C3=CC=CC=C3",3.256,5,1,5]
["S4657","Eslicarbazepine Acetate","f4","L1300-19","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC",null,"211199","Neurological Disease","BACE,Sodium Channel","Neuronal Signaling","Eslicarbazepine Acetate (BIA 2093, Zebinix, Exalief, Stedesa, Aptiom), an antiepileptic drug, is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel.",296.32,"236395-14-5",59,199.11,"<1",0,"http://selleckchem.com/products/eslicarbazepine-acetate.html","C17H16N2O3","free base","BIA 2093, Zebinix, Exalief, Stedesa, Aptiom","CC(=O)OC1CC2=C(C=CC=C2)N(C(N)=O)C3=C1C=CC=C3",2.4,3,1,2]
["S4658","Hydroquinidine","g4","L1300-19","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Others","Others","Hydroquinidine (Dihydroquinidine, Hydroconchinine, Hydroconquinine, Dihydroquinine) is an antiarrhythmic agent.",326.43,"1435-55-8",65,199.12,"<1",0,"http://selleckchem.com/products/hydroquinidine.html","C20H26N2O2","free base","Dihydroquinidine, Hydroconchinine, Hydroconquinine, Dihydroquinine","CCC1CN2CCC1CC2C(O)C3=C4C=C(OC)C=CC4=NC=C3",3.124,2,1,4]
["S4660","Glycopyrrolate","h4","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37","040568,040653,040821,040836,040844,040847,081169,085562,085563,086178,086900,086902,086947,088475,089335,089393,089397,090020,090195,090963,091182,091413,091522,202675,203657,207201,207639,208973,209024,209328,210244,210842,210927,211334,211705","Neurological Disease","AChR","Neuronal Signaling","Glycopyrrolate (Glycopyrronium, Robinul, Gastrodyn) is a muscarinic antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with some anesthetics.",398.33,"596-51-0",65,163.18,79,198.33,"http://selleckchem.com/products/glycopyrrolate.html","C19H28NO3.Br","bromide","Glycopyrrolate bromide, Glycopyrronium bromide, Robinul, Gastrodyn","[Br-].C[N+]1(C)CCC(C1)OC(=O)C(O)(C2CCCC2)C3=CC=CC=C3",-0.961,2,0,5]
["S4661","Tiagabine hydrochloride","a5","L1300-19","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","077555,206857,208181","Neurological Disease/Psychotic disorders","GABA Receptor","Neuronal Signaling","Tiagabine Hydrochloride (Gabitril, NO050328, NO328, TGB) is the hydrochloride salt form of tiagabine, a nipecotic acid derivative with anticonvulsant property. A selective gamma-aminobutyric acid (GABA) reuptake inhibitor.",412.01,"145821-59-6",82,199.02,11,26.7,"http://selleckchem.com/products/tiagabine-hydrochloride.html","C20H25NO2S2.HCl","hydrochloride","Gabitril hydrochloride, NO050328 hydrochloride, NO328 hydrochloride, TGB hydrochloride","Cl.CC1=C(SC=C1)C(=CCCN2CCCC(C2)C(O)=O)C3=C(C)C=CS3",2.634,1,0,6]
["S4662","Atazanavir","b5","L1300-19","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","Martindale:The Extra Pharmacopoeia,EP9.7,Ph.Int_6th,IP2010","091641","Infection","HIV Protease,P450 (e.g. CYP17),P-gp","Proteases","Atazanavir (Latazanavir, Zrivada, Reyataz, BMS-232632) is an azapeptide and HIV-protease inhibitor that is used in the treatment of HIV infections and AIDS in combination with other anti-HIV agents. Atazanavir is a substrate and inhibitor of cytochrome P450 isozyme 3A (CYP3A4) and an inhibitor and inducer of P-glycoprotein.",704.86,"198904-31-3",71,100.73,"<1",0,"http://selleckchem.com/products/atazanavir-reyataz.html","C38H52N6O7","free base","Latazanavir, Zrivada, Reyataz, BMS-232632","COC(=O)NC(C(=O)NC(CC1=CC=CC=C1)C(O)CN(CC2=CC=C(C=C2)C3=NC=CC=C3)NC(=O)C(NC(=O)OC)C(C)(C)C)C(C)(C)C",4.69,7,5,18]
["S4663","Fusidate Sodium","c5","L1300-19","in 10mM DMSO","DMF,CFDA,NDC,PMDA,HMA","KP Ⅹ,EP9.0",null,"Infection","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Bacterial","Microbiology","Fusidate Sodium (Fucidin, SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections.",538.69,"751-94-0",100,185.64,100,185.64,"http://selleckchem.com/products/fusidate-sodium.html","C31H47O6.Na","sodium salt","Fucidin, Sodium fusidate, SQ-16360","[Na+].CC1C(O)CCC2(C)C1CCC3(C)C2C(O)CC4\\C(C(CC34C)OC(C)=O)=C(/CCC=C(C)C)C([O-])=O",3.623,2,2,6]
["S4664","Molsidomine","d5","L1300-19","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017",null,"Cardiovascular Disease","Others","Others","Molsidomine (SIN-10, Corvaton, Morsydomine) is an orally active, long acting vasodilating drug. Molsidomine is metabolized in the liver to the active metabolite linsidomine. Linsidomine is an unstable compound that releases nitric oxide (NO) upon decay as the actual vasodilating compound.",242.23,"25717-80-0",48,198.16,9,37.15,"http://selleckchem.com/products/molsidomine.html","C9H14N4O4","inner salt","SIN-10, Corvaton, Morsydomine","CCOC(=O)[N-]C1=C[N+](=NO1)N2CCOCC2",0.42,5,0,4]
["S4665","Rabeprazole sodium","e5","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA",null,"076822,076824,076885,078964,090678,202376,204179,204237,205761,208644","Inflammation","Proton Pump","Transmembrane Transporters","Rabeprazole (Aciphex, Dexrabeprazole, Habeprazole) is an antiulcer drug in the class of proton pump inhibitors.",381.42,"117976-90-6",76,199.26,76,199.26,"https://www.selleckchem.com/products/rabeprazole-sodium.html","C18H20N3O3S.Na","sodium salt","Aciphex Sodium, Dexrabeprazole Sodium, Habeprazole Sodium","COCCCOC1=C(C)C(=NC=C1)C[S](=O)C2=NC3=CC=CC=C3[N]2[Na]",2.47,5,0,8]
["S4666","Sivelestat sodium tetrahydrate","f5","L1300-19","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Respiratory Disease","Serine Protease","Proteases","Sivelestat sodium tetrahydrate (ONO5046-Na, EI546, LY544349) is a competitive inhibitor of human neutrophil elastase, also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse.",528.51,"201677-61-4",100,189.21,"<1",0,"http://selleckchem.com/products/sivelestat-sodium.html","C20H21N2O7S.4H2O.Na","sodium salt","Sivelestat sodium, ONO5046-Na, Sodium sivelestat, EI546 sodium, LY544349 sodium","O.O.O.O.[Na+].CC(C)(C)C(=O)OC1=CC=C(C=C1)[S](=O)(=O)NC2=CC=CC=C2C(=O)NCC([O-])=O",0.018,5,2,9]
["S4667","Lidocaine hydrochloride","g5","L1300-19","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,Ph.Int_6th,BP2017,IP2010","017508,017701,018543,040013,040014,040078,040433,040710,040837,080377,080390,080407,080414,080420,080504,080710,080760,080850,081318,083083,083135,083158,083173,083198,083387,083388,083627,084626,085037,085131,086283,086761,087872,087881,087980,088294,088328,088329,088330,088331,088803,089362,089688,091056,091058,091564,202242,204494,207182,208017,208474","Cardiovascular Disease/Neurological Disease","EGFR","Angiogenesis","Lidocaine hydrochloride (Lidothesin, Lignocaine, Xyloneural) is an inhibitor of epidermal growth factor receptor (EGFR) and has antiproliferative effect on human tongue cancer cells. Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmia agent.",270.8,"73-78-9",54,199.41,54,199.41,"http://selleckchem.com/products/lidocaine-hydrochloride.html","C14H22N2O.HCl","hydrochloride","Lidocaine HCL, Lidothesin, Lignocaine hydrochloride, Xyloneural","Cl.CCN(CC)CC(=O)NC1=C(C)C=CC=C1C",3.008,1,1,5]
["S4669","Benzocaine hydrochloride","h5","L1300-19","in 10mM DMSO","DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,Ph.Int_6th,BP2017",null,"Neurological Disease","Sodium Channel","Transmembrane Transporters","Benzocaine hydrochloride (Ethyl 4-aminobenzoate, Ethyl p-aminobenzoate) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.",201.65,"23239-88-5",40,198.36,"<1",0,"http://selleckchem.com/products/benzocaine-hydrochloride.html","C9H11NO2.HCl","hydrochloride","Ethyl 4-aminobenzoate hydrochloride, Benzocaine HCl, Ethyl p-aminobenzoate hydrochloride","Cl.CCOC(=O)C1=CC=C(N)C=C1",1.669,2,1,3]
["S4672","Dimenhydrinate","a6","L1300-19","in 10mM DMSO","FDA,CFDA,DMF,NDC,PMDA,HMA","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,KP Ⅹ,JP17,BP2017","040519,080615,080715,080841,083531,084316,084767,085166,085985","Neurological Disease","Histamine Receptor","Neuronal Signaling","Dimenhydrinate is an over-the-counter drug used to prevent nausea, vomiting, and dizziness caused by motion sickness.",469.96,"523-87-5",94,200.02,"<1",0,"http://www.selleck.cn/products/dimenhydrinate.html","C24H28ClN5O3","Free Base","N/A","CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.CN3C(=O)N(C)C4=C([NH]C(=N4)Cl)C3=O",3.955,4,1,6]
["S4673","Etonogestrel","b6","L1300-19","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia","021529,021529,021187","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Etonogestrel (Implanon, Nexplanon, 3-Oxodesogestrel, 3-keto-Desogestrel) is a synthetic form of the naturally occurring female sex hormone progesterone. It binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor mediated gene expression.",324.46,"54048-10-1",64,197.25,"<1",0,"http://selleckchem.com/products/etonogestrel.html","C22H28O2","free base","Implanon, Nexplanon, 3-Oxodesogestrel, 3-keto-Desogestrel","CCC12CC(=C)C3C(CCC4=CC(=O)CCC34)C1CCC2(O)C#C",4.827,1,0,1]
["S4674","Hydroxyprogesterone caproate","c6","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,IP2010","017439,018004,089330,089331,200271,208381,210618,210723,210877,211070,211071,211142","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Hydroxyprogesterone Caproate (17α-Hydroxyprogesterone hexanoate, 17α-Hydroxyprogesterone caproate) is a synthetic progestational agent. It binds to and activates nuclear progesterone receptors in the reproductive system and inhibits ovulation and an alteration in the cervical mucus and endometrium.",428.6,"630-56-8",85,198.32,"<1",0,"http://selleckchem.com/products/hydroxyprogesterone-caproate.html","C27H40O4","free base","17α-Hydroxyprogesterone hexanoate, 17α-Hydroxyprogesterone caproate","CCCCCC(=O)OC1(CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C)C(C)=O",5.539,4,0,7]
["S4676","Gluconolactone","d6","L1300-19","in 10mM DMSO","FDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","019481","Others","Others","Others","Gluconolactone is a naturally occurring polyhydroxy acid with metal chelating, moisturizing and antioxidant activity.",178.14,"90-80-2",35,196.47,35,196.47,"http://www.selleckchem.com/products/gluconolactone.html","C6H10O6","Free Base","N/A","OCC1OC(=O)C(O)C(O)C1O",-2.229,2,4,1]
["S4678","Povidone iodine","e6","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,JP17,USP39-NF34,IP2010,KP Ⅹ","019522","Infection","Anti-infection,Hydrotropic Agents","Microbiology","Povidone iodine (Betadine, PVP iodine, PVP-I, Isodine) is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It is used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol.",0,"25655-41-8",28,10,28,0,"http://selleckchem.com/products/povidone-iodine.html","(C6H9NO)x.xI2","free base","Betadine, PVP iodine, PVP-I, Isodine","CCC(C)N1CCCC1=O",0,0,0,0]
["S4679","Terazosin HCl","f6","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,BP2017,IP2010","074315,074446,074530,074657,074823,075140,075317,075384,075498,075614,075667,076021","Cardiovascular Disease","Adrenergic Receptor","GPCR & G Protein","Terazosin (Hytrin, Zayasel, Terazosine, Flumarc, Fosfomic, Blavin) is a selective alpha-1 antagonist used for treatment of symptoms of an enlarged prostate (BPH). It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls.",423.89,"63074-08-8",84,198.16,1,2.36,"http://selleckchem.com/products/terazosin.html","C19H25N5O4.HCl","hydrochloride","Hytrin, Zayasel, Terazosine, Flumarc, Fosfomic, Blavin","Cl.COC1=CC2=C(C=C1OC)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N",1.762,6,1,4]
["S4682","Loxoprofen","g6","L1300-19","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Loxoprofen (Koloxo, Loxoprofene, Loxoprofeno) is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group.",246.3,"68767-14-6",49,198.94,"<1",0,"http://selleckchem.com/products/loxoprofen.html","C15H18O3","free base","Koloxo, Loxoprofene, Loxoprofeno","CC(C(O)=O)C1=CC=C(CC2CCCC2=O)C=C1",2.936,2,0,4]
["S4683","Sildenafil Mesylate","h6","L1300-19","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017,IP2010","077342,078380,091378,091379,091448,091479,200149,200165,201150,201171,202023,202025,202255,202503,202506,202597,202598,202659,203623,203814,203962,203963,203988,204882,204883,206401,207178,208494,210394,212051,212260","Others","PDE","Metabolism","Sildenafil Mesylate(UK-92480 Mesylate) is a mesylate form of Sildenafil, an inhibitor of Phosphodiesterase 5.","474.58(free base)","1308285-21-3",100,211,100,0,"http://selleckchem.com/products/sildenafil-mesylate.html","C22H30N6O4S.xCH4O3S","Mesylate","UK-92480 Mesylate","CCCC1=N[N](C)C2=C1N=C(NC2=O)C3=CC(=CC=C3OCC)[S](=O)(=O)N4CCN(C)CC4.C[S](O)(=O)=O",1.833,6,1,7]
["S4685","Efavirenz","a7","L1300-19","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,Ph.Int_6th,IP2010","022461,077673,077916,078064,078509,078883,078886,078958,090155,091175,091471,091579,202042,202301,202990,204766,204869,205322,205389,207895","Infection","Reverse Transcriptase","Microbiology","Efavirenz (Sustiva, Stocrin, DMP-266) is a synthetic non-nucleoside reverse transcriptase (RT) inhibitor with antiviral activity.",315.67,"154598-52-4",63,199.58,"<1",0,"http://selleckchem.com/products/efavirenz.html","C14H9ClF3NO2","free base","Sustiva, Stocrin, DMP-266, DMP 266","FC(F)(F)C1(OC(=O)NC2=C1C=C(Cl)C=C2)C#CC3CC3",4.381,2,1,3]
["S4686","Vitamin E","b7","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP39-NF34,IP2010","006071,018440,021625,021643,018920,008809,008809,018933,018439,020176","Nutritional support","COX,VEGFR","Neuronal Signaling","Vitamin E (D-alpha-Tocopherol) is a fat-soluble vitamin with potent antioxidant properties. It is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription.",430.71,"59-02-9","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/vitamin-e.html","C29H50O2","free base","Alpha-Tocopherol, D-alpha-Tocopherol, 5,7,8-Trimethyltocol|(+)-alpha-Tocopherol","CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=C(C)C(=C(C)C(=C2O1)C)O",10.44,1,1,12]
["S4687","Rivastigmine","c7","L1300-19","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","077363,204403,205622,206318,207308","Neurological Disease","AChR","Neuronal Signaling","Rivastigmine (SDZ-ENA 713, Exelon) is a cholinesterase inhibitor with IC50 of 5.5 μM. It inhibits acetylcholinesterase (IC50 = 4.15 µM) and butyrylcholinesterase (IC50 = 37 nM).",250.34,"123441-03-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/rivastigmine.html","C14H22N2O2","free base","SDZ-ENA 713, Exelon","CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C",2.599,2,0,5]
["S4689","Deoxycholic acid","d7","L1300-19","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37","206333","Gastroenterology","GPCR19","GPCR & G Protein","Deoxycholic acid (Deoxycholate, Desoxycholic acid, Cholerebic, Cholorebic) is a cytolytic agent. The physiologic effect of deoxycholic acid is by means of decreased cell membrane integrity.  Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.",392.57,"83-44-3",78,198.69,"<1",0,"http://selleckchem.com/products/deoxycholic-acid.html","C24H40O4","free base","Deoxycholate, Desoxycholic acid, Cholerebic, Cholorebic","CC(CCC(O)=O)C1CCC2C3CCC4CC(O)CCC4(C)C3CC(O)C12C",4.082,1,2,4]
["S4690","Escin","e7","L1300-19","in 10mM DMSO",null,"USP36-NF31",null,"Angiology/Infection","Immunology & Inflammation related","Immunology & Inflammation","Escin (Aescin) is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum(the horse chestnut).",1131.26,"6805-41-0",66,58.34,"<1",0,"http://selleckchem.com/products/escin.html","C55H86O24","free base","Aescin","C\\C=C(C)/C(=O)OC1C(OC(C)=O)C2(CO)C(O)CC3(C)C(=CCC4C5(C)CCC(OC6OC(C(OC7OC(CO)C(O)C(O)C7O)C(O)C6OC8OC(CO)C(O)C(O)C8O)C(O)=O)C(C)(CO)C5CCC34C)C2CC1(C)C",-0.723,11,12,16]
["S4691","Oxybenzone","f7","L1300-19","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","020045","Others","Others","Others","Oxybenzone is a benzophenone derivative used as a sunscreen agent.",228.24,"131-57-7",45,197.16,"<1",0,"http://selleckchem.com/products/oxybenzone.html","C14H12O3","free base","Eusolex 4360, Escalol 567, KAHSCREEN BZ-3, Benzophenone 3","COC1=CC(=C(C=C1)C(=O)C2=CC=CC=C2)O",2.975,2,1,3]
["S4692","Succimer","g7","L1300-19","in 10mM DMSO","FDA,CFDA,DMF,NDC","Martindale the Extra Pharmacopoei","019998","Hematology","Others","Others","Succimer (DMSA, meso-2,3-dimercaptosuccinic acid) is an orally active metal chelator is used to treat heavy metal poisoning.",182.22,"304-55-2",36,197.56,"<1",0,"http://www.selleck.cn/products/succimer.html","C4H6O4S2","Free Base","DMSA, meso-2,3-dimercaptosuccinic acid","OC(=O)C(S)C(S)C(O)=O",0.279,2,0,3]
["S4693","Guanfacine Hydrochloride","h7","L1300-19","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","074145,074673,074762,074796,075109,200881,201382,201408,202238,202568,202578,205430,205689","Cardiovascular Disease/Neurological Disease","Adrenergic Receptor","Neuronal Signaling","Guanfacine Hydrochloride (Tenex, Intuniv) is a selective α2A-adrenoceptor agonist with anti-hypertensive effect.",282.55,"29110-48-3",56,198.2,30,106.18,"http://selleckchem.com/products/guanfacine-hydrochloride.html","C9H9Cl2N3O.HCl","hydrochloride","Guanfacine, Tenex, Intuniv","Cl.NC(=N)NC(=O)CC1=C(Cl)C=CC=C1Cl",2.412,1,2,3]
["S4695","D panthenol","a8","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","006071,021163,021559,021265,021646,018440,021625,021643,018920,008809,008809,018933,018439","Inflammation","Vitamin","Metabolism","D panthenol (Dexpanthenol, D-Panthenol, Pantothenol, Ilopan, D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent.",205.25,"81-13-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/d-panthenol.html","C9H19NO4","free base","Dexpanthenol, D-Panthenol, Pantothenol, Ilopan, D-Pantothenyl alcohol","CC(C)(CO)C(O)C(=O)NCCCO",-1.266,1,4,6]
["S4696","CarbinoxaMine Maleate","b8","L1300-19","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","040442,040458,040639,040814,090417,090418,090435,090756,207484","Immunology/Inflammation","Histamine Receptor","Neuronal Signaling","Carbinoxamine maleate is a histamine-H1 receptor blocking agent with antihistamine and anticholinergic properties.",406.86,"3505-38-2",81,199.09,81,199.09,"http://selleckchem.com/products/carbinoxamine-maleate.html","C16H19ClN2O.C4H4O4","maleate","N/A","CN(C)CCOC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.OC(=O)\\C=C/C(O)=O",0.224,4,0,8]
["S4697","Saxagliptin hydrate","c8","L1300-19","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC",null,"205902,205941,205959,205972,205994,206020","Endocrinology/Metabolic Disease","DPP","Proteases","Saxagliptin H2O (BMS-477118, Onglyza) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.",333.43,"945667-22-1",66,197.94,1,3,"http://selleckchem.com/products/saxagliptin-hydrate.html","C18H25N3O2.H2O","hydrate","BMS-477118 hydrate, Onglyza hydrate, BMS 477118 hydrate, BMS477118 hydrate","O.NC(C(=O)N1C(CC2CC12)C#N)[C]34CC5[CH2]C(C[C](O)(C5)C3)C4",0.068,1,1,2]
["S4698","Vitamin K1","d8","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC",null,"087954,087955,087956","Hematology","Vitamin","Metabolism","Vitamin K1 (Phyllohydroquinone, Phylloquinone, Phytomenadione, Phytonadione), made by plants, is a major type of dietary vitamin K, which is well-known for its role in blood clotting. Vitamin K1 is directly involved in photosynthesis.",450.7,"84-80-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"https://www.selleckchem.com/products/vitamin-k1.html","C31H46O2",0,"Phyllohydroquinone, Phylloquinone, Phytomenadione, Phytonadione","CC(C)CCCC(C)CCCC(C)CCC/C(C)=C/CC1=C(C)C(=O)C2=C(C=CC=C2)C1=O",10.25,2,0,14]
["S4699","Etretinate","e8","L1300-19","in 10mM DMSO","FDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia","019369","Immunology","Retinoid Receptor","Metabolism","Etretinate (Tegison, Ethyl etrinoate, Retinoid, Etretinato,Ro 10-9359) is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells.",354.48,"54350-48-0",70,197.47,"<1",0,"http://selleckchem.com/products/etretinate.html","C23H30O3","free base","Tegison, Ethyl etrinoate, Retinoid, Etretinato,Ro 10-9359","CCOC(=O)/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)C(=C(OC)C=C1C)C",6.24,3,0,8]
["S4701","2-Deoxy-D-glucose (2-DG)","f8","L1300-19","in 10mM DMSO","DMF","IP2010",null,"Cancer/Infection/Neurological Disease","Apoptosis related,Carbohydrate Metabolism,HSV","Metabolism","2-Deoxy-D-glucose (2-DG, 2-deoxyglucose, NSC 15193, 2-Deoxy-D-arabino-hexose, D-Arabino-2-deoxyhexose), an analog of glucose, is a glycolytic inhibitor with antiviral activity. 2-Deoxy-D-glucose induces apoptosis and inhibits Herpes Simplex Virus type-1 (HSV-1) receptor expression.",164.16,"154-17-6",32,194.93,32,194.93,"http://selleckchem.com/products/2-deoxy-d-glucose.html","C6H12O5","free base","2-deoxyglucose, NSC 15193, 2-Deoxy-D-arabino-hexose, D-Arabino-2-deoxyhexose","OCC1OC(O)CC(O)C1O",-1.748,1,3,1]
["S4706","Eugenol","g8","L1300-19","in 10mM DMSO","CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017,IP2010",null,"Immunology","Immunology & Inflammation related","Immunology & Inflammation","Eugenol (4-Allyl-2-methoxyphenol, 4-Allylguaiacol, Eugenic acid, Allylguaiacol) is a naturally occuring scent chemical found in clove oil and other plants. The physiologic effect of eugenol is by means of increased Histamine Release, and cell-mediated Immunity.",164.2,"97-53-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/eugenol.html","C10H12O2","Free Base","4-Allyl-2-methoxyphenol, 4-Allylguaiacol, Eugenic acid, Allylguaiacol","COC1=C(O)C=CC(=C1)CC=C",2.579,1,1,3]
["S4707","Oleic Acid","h8","L1300-19","in 10mM DMSO","DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010",null,"Others","ATPase","Transmembrane Transporters","Oleic acid (Oleate, 9-Octadecenoic Acid, Elaidoic acid) is a fatty acid that occurs naturally in various animal and vegetable fats and oils. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent.  Oleic acid is an abundant monounsaturated fatty acid. Oleic acid is a Na+/K+ ATPase activator.",282.46,"112-80-1","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/oleic-acid.html","C18H34O2","Free Base","Oleate, 9-Octadecenoic Acid, Elaidoic acid","CCCCCCCC\\C=C/CCCCCCCC(O)=O",6.86,1,0,15]
["S4709","Latanoprost","a9","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","076218,077697,090887,091449,200925,201006,201786,202077,202442","Ophthalmology","GPR,Immunology & Inflammation related,RAR/RXR","Immunology & Inflammation","Latanoprost (Xalatan, PhXA41) is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. Latanoprost increases uveoscleral outflow and thereby reduces intraocular pressure.",432.59,"130209-82-4","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/latanoprost.html","C26H40O5","Free Base","Xalatan, PhXA41, PHXA-41","CC(C)OC(=O)CCC\\C=C/CC1C(O)CC(O)C1CCC(O)CCC2=CC=CC=C2",4.365,2,3,14]
["S4711","Esculetin","b9","L1300-19","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Lipoxygenase","Metabolism","Esculetin (Cichorigenin, Aesculetin) is a coumarin derivative found in various natural plant products with various biological and pharmaceutical properties including anti-edema, anti-inflammatory and anti-tumour effects. It inhibits lipoxygenases (LOs).",178.14,"305-01-1",35,196.47,"<1",0,"http://selleckchem.com/products/esculetin.html","C9H6O4","free base","Cichorigenin, Aesculetin","OC1=CC2=C(C=CC(=O)O2)C=C1O",1.415,2,2,0]
["S4714","(-)-Menthol","c9","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017,IP2010,JP17","022029","Respiratory Disease","TRP Channel","Transmembrane Transporters","(-)-Menthol is a levo isomer of menthol and used as a cooling agent that strongly activates TRPM8.",156.27,"2216-51-5",31,198.37,16,102.39,"http://selleckchem.com/products/-menthol.html","C10H20O","free base","L-Menthol, Levomenthol, Menthomenthol, Menthacamphor","CC(C)C1CCC(C)CC1O",2.779,0,1,1]
["S4716","Evans Blue","d9","L1300-19","in 10mM DMSO","FDA",null,"008041","Diagnosis","GluR","Neuronal Signaling","Evans Blue (Direct Blue 53,C.I.23860) is a potent inhibitor of the uptake of L-glutamate into synaptic vesicles, also an AMPA/kainate receptor antagonist.",960.81,"314-13-6",100,104.08,100,104.08,"http://selleckchem.com/products/evans-blue.html","C34H24N6O14S4.4Na","sodium salt","Direct Blue 53,C.I.23860","CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N=NC3=C(O)C4=C(N)C(=CC(=C4C=C3)[S](=O)(=O)O[Na])[S](=O)(=O)O[Na])C)N=NC5=C(O)C6=C(N)C(=CC(=C6C=C5)[S](=O)(=O)O[Na])[S](=O)(=O)O[Na]",6.593,8,4,13]
["S4717","Isatin","e9","L1300-19","in 10mM DMSO",null,"EP9.2;BP2017",null,"Others","MAO","Metabolism","Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor with an IC50 of 15 μM and more active against MAO-B than MAO-A.",147.13,"91-56-5",29,197.1,"<1",0,"http://selleckchem.com/products/isatin.html","C8H5NO2","free base","2,3-Indolinedione","O=C1NC2=C(C=CC=C2)C1=O",0.67,2,1,0]
["S4718","Acetylcholine iodide","f9","L1300-19","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","016211","Others","AChR","Neuronal Signaling","Acetylcholine iodide (Acetylcolina) is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.",273.11,"2260-50-6",54,197.72,54,197.72,"http://selleckchem.com/products/acetylcholine-iodide.html","C7H16NO2.I","iodide salt","Acetylcolina","[I-].CC(=O)OCC[N+](C)(C)C",-4.308,2,0,4]
["S4720","Cefotaxime","g9","L1300-19","in 10mM DMSO","FDA,CFDA,DMF,NDC,PMDA,HMA","Martindale the Extra Pharmacopoei,USP42-NF37,EP8.8,KP Ⅹ,JP17,BP2017,IP2010","064200,064201,065071,065072,065197","Infection","Antibiotics,Antibiotics for Plant Cell Culture,Bacterial","Microbiology","Cefotaxime(HR-756) is a third-generation cephalosporin antibiotic and has broad spectrum activity against Gram positive and Gram negative bacteria.",455.47,"63527-52-6",91,199.79,"<1",0,"http://www.selleck.cn/products/cefotaxime.html","C16H17N5O7S2","Free Base","HR-756","CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)COC(C)=O)C3=CSC(=N3)N",-0.91,8,2,8]
["S4722","(+)-Catechin","h9","L1300-19","in 10mM DMSO",null,"BP2019;EP9.2",null,"Metabolic Disease","Antioxidant","Immunology & Inflammation","(+)-Catechin (Cianidanol, Catechinic acid, Catechuic acid) is an antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.,",290.27,"154-23-4",58,199.81,58,199.81,"http://selleckchem.com/products/catechin.html","C15H14O6","free base","Cianidanol, Catechinic acid, Catechuic acid, Catechin","OC1CC2=C(OC1C3=CC(=C(O)C=C3)O)C=C(O)C=C2O",2.021,1,5,1]
["S4723","(-)Epicatechin","a10","L1300-19","in 10mM DMSO",null,"BP2019;Martindale:The Extra Pharmacopoeia",null,"Cancer/Cardiovascular Disease","Antioxidant","Immunology & Inflammation","(−)Epicatechin (L-Epicatechin, (-)-Epicatechol) is a flavonoid present in cocoa, green tea and red wine. It is a strong antioxidant, has insulin mimic action and improves heart health.",290.27,"490-46-0",58,199.81,"<1",0,"http://selleckchem.com/products/-epicatechin.html","C15H14O6","free base","L-Epicatechin, (-)-Epicatechol","OC1CC2=C(OC1C3=CC(=C(O)C=C3)O)C=C(O)C=C2O",2.021,1,5,1]
["S4725","Benzenesulfonamide","b10","L1300-19","in 10mM DMSO","DMF","USP42-NF37",null,"Others","Carbonic Anhydrase","Metabolism","Benzenesulfonamide (Benzenesulphonamide, Benzosulfonamide, Phenyl sulfonamide, Benzene sulfonamide) is an inhibitor of carbonic anhydrases.",157.19,"98-10-2",31,197.21,"<1",0,"http://selleckchem.com/products/benzenesulfonamide.html","C6H7NO2S","free base","Benzenesulphonamide, Benzosulfonamide, Phenyl sulfonamide, Benzene sulfonamide","N[S](=O)(=O)C1=CC=CC=C1",0.535,2,1,1]
["S4726","Lauric Acid","c10","L1300-19","in 10mM DMSO","DMF,NDC","USP42-NF37,EP9.1,BP2017",null,"Others","Anti-infection","Microbiology","Lauric Acid (dodecanoic acid, N-Dodecanoic acid, Dodecylic acid) is a saturated medium-chain fatty acid with a 12-carbon backbone. Lauric acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.",200.32,"143-07-7",40,199.68,20,99.84,"http://selleckchem.com/products/lauric-acid.html","C12H24O2","free base","dodecanoic acid, N-Dodecanoic acid, Dodecylic acid","CCCCCCCCCCCC(O)=O",4.568,1,0,10]
["S4727","Cinnarizine","d10","L1300-19","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.2,BP2017",null,"Neurological Disease","Calcium Channel","Transmembrane Transporters","Cinnarizine (Stugeron, Dimitronal, Stutgin, Cinarizine) is a medication derivative of piperazine, and characterized as an antihistamine and a calcium channel blocker.",368.51,"298-57-7",73,198.1,"<1",0,"http://selleckchem.com/products/cinnarizine.html","C26H28N2","free base","Stugeron, Dimitronal, Stutgin, Cinarizine","C1CN(CCN1C\\C=C\\C2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=CC=C4",5.524,0,0,6]
["S4731","Perphenazine","e10","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,BP2017,JP16,IP2010","040226,040360,089456,089457,089683,089684,089685,089686,089707,089708,205056,205973,206691,207582","Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Perphenazine (Perphenazin, Trilafon, Etaperazine) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.",403.97,"58-39-9",74,183.18,"<1",0,"http://selleckchem.com/products/perphenazine.html","C21H26ClN3OS","free base","Perphenazin, Trilafon, Etaperazine","OCCN1CCN(CCCN2C3=CC=CC=C3SC4=C2C=C(Cl)C=C4)CC1",4.157,0,1,6]
["S4733","Retigabine","f10","L1300-19","in 10mM DMSO","EMA",null,null,"Neurological Disease","Potassium Channel","Transmembrane Transporters","Retigabine (D-23129) is a novel anticonvulsant with activity in a broad range of seizure models. The mechanism of action involves opening of neuronal K(V)7.2-7.5 (formerly KCNQ2-5) voltage-activated K(+) channels.",303.33,"150812-12-7",60,197.8,"<1",0,"http://selleckchem.com/products/retigabine.html","C16H18FN3O2","free base","D-23129, N-(2-amino-4-[fluorobenzylamino]-phenyl) carbamic acid","CCOC(=O)NC1=CC=C(NCC2=CC=C(F)C=C2)C=C1N",2.793,2,3,6]
["S4734","Retigabine 2HCl","g10","L1300-19","in 10mM DMSO","EMA",null,null,"Neurological Disease","Potassium Channel","Transmembrane Transporters","Retigabine 2HCl (D-23129) is a novel anticonvulsant with activity in a broad range of seizure models. The mechanism of action involves opening of neuronal K(V)7.2-7.5 (formerly KCNQ2-5) voltage-activated K(+) channels.",376.25,"150812-13-8",75,199.34,75,199.34,"http://selleckchem.com/products/retigabine-2hcl.html","C16H18FN3O2.2HCl","dihydrochloride","N-(2-amino-4-[fluorobenzylamino]-phenyl) carbamic acid (2HCl), D-23129 2HCl","Cl.Cl.CCOC(=O)NC1=CC=C(NCC2=CC=C(F)C=C2)C=C1N",3.557,2,3,6]
["S4735","Salvianolic acid B","h10","L1300-19","in 10mM DMSO",null,"BP2017;EP8.7",null,"Neurological Disease","Sirtuin","Epigenetics","Salvianolic acid B (Sal B, Lithospermate B, Lithospermic acid B), an antioxidant and free radical scavenging compound, is the most abundant bioactive compound extracted from the root of Salvia miltiorrhiza Bunge.",718.61,"121521-90-2",100,139.16,100,139.16,"http://selleckchem.com/products/salvianolic-acid-b.html","C36H30O16","free base","Sal B, Lithospermate B, Lithospermic acid B","OC(=O)C(CC1=CC(=C(O)C=C1)O)OC(=O)/C=C/C2=CC=C(O)C3=C2C(C(O3)C4=CC=C(O)C(=C4)O)C(=O)OC(CC5=CC=C(O)C(=C5)O)C(O)=O",4.718,7,7,14]
["S4736","Trapidil","a11","L1300-19","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.2,JP17,BP2017",null,"Angiology","PDGFR","Protein Tyrosine Kinase","Trapidil (Rocornal, Trapymin, Avantrin, Trapymine) is a PDGF antagonist that can inhibit the proliferation of the PDGF-producing glioma cells.",205.26,"15421-84-8",41,199.75,41,199.75,"http://selleckchem.com/products/trapidil.html","C10H15N5","free base","Rocornal, Trapymin, Avantrin, Trapymine","CCN(CC)C1=CC(=NC2=NC=N[N]12)C",1.922,3,0,3]
["S4737","Psoralen","b11","L1300-19","in 10mM DMSO",null,"IP2010",null,"Cancer","ADC Cytotoxin,DNA/RNA Synthesis","DNA Damage/DNA Repair","Psoralen (Psoralene, Ficusin, Furocoumarin) is a naturally occurring furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.",186.16,"66-97-7",37,198.75,"<1",0,"http://selleckchem.com/products/psoralen.html","C11H6O3","free base","Psoralene, Ficusin, Furocoumarin","O=C1OC2=C(C=C1)C=C3C=COC3=C2",2.203,3,0,0]
["S4744","Anethole trithione","c11","L1300-19","in 10mM DMSO","CFDA","Martindale the Extra Pharmacopoei",null,"Others","Others","Others","Anethole trithione is a drug used in the treatment of dry mouth.",240.36,"532-11-6",48,199.7,"<1",0,"http://www.selleck.cn/products/anethole-trithione.html","C10H8OS3","Free Base","N/A","COC1=CC=C(C=C1)C2=CC(=S)SS2",3.635,1,0,2]
["S4748","Ondansetron Hydrochloride Dihydrate","d11","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","EP9.1,BP2017","076183,076252,076695,076781,076876,076930,076930,076960,076967,076974,077009,077050,077112,077172,077303,077306,077365,077368,077430,077473,077517,077535,077544,077545,077577,077582,077729,077840,077851,078127,078180,078257,078288,078539,078776,079039,079224,090116,090424,090648,090883,091342,091483,202599,203711,203761,204906,206846","Gastroenterology","5-HT Receptor","Neuronal Signaling","Ondansetron is a highly specific and selective serotonin 5-HT3 receptor antagonist (Ki=6.16 nM), with low affinity for dopamine receptors.",365.85,"103639-04-9",73,199.54,73,199.54,"http://selleckchem.com/products/ondansetron-hcl.html","C18H19N3O.HCl.2H2O","hydrochloride","N/A","O.O.Cl.C[N]1C2=C(C(=O)C(CC2)C[N]3C=CN=C3C)C4=C1C=CC=C4",2.602,2,0,2]
["S4749","Citalopram HBr","e11","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.3,BP2017,IP2010","021763,077031,077032,077033,077034,077035,077036,077037,077038,077039,077040,077041,077042,077043,077044,077045,077046,077048,077052,077141,077213,077232,077278,077289,077534,077601,077629,077654,077668,077812,078216,201450,205407","Psychotic disorders","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Citalopram HBr (Nitalapram HBr, Prepram HBr, Bonitrile HBr, Lu 10-171 HBr), an antidepressant, is an orally administered selective serotonin reuptake inhibitor (SSRI) with IC50 of 1.8 nM.",405.3,"59729-32-7",81,199.85,81,199.85,"http://selleckchem.com/products/citalopram-hbr.html","C20H21FN2O.HBr","hydrobromide","Nitalapram HBr, Prepram HBr, Bonitrile HBr, Lu 10-171 HBr","Br.CN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C3=CC=C(F)C=C3",4.212,1,0,5]
["S4750","Sulfacetamide sodium salt hydrate","f11","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017,Ph.Int_5th,USP39-NF34","040066,040215,040216,077015,078649,078668,080029,088947,089068,089560","Infection","Antibiotics,Autophagy,Bacterial","Autophagy","Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase(DHPS) with IC50 of 9.5 μM. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid.",254.24,"6209-17-2",50,196.66,50,196.66,"http://selleckchem.com/products/sulfacetamide-sodium-salt-hydrate.html","C8H9N2O3S.H2O.Na","sodium salt hyd","N/A","O.CC(=O)N([Na])[S](=O)(=O)C1=CC=C(N)C=C1",-0.326,3,1,2]
["S4751","Cisapride hydrate","g11","L1300-19","in 10mM DMSO","FDA,DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2010","020210,020398,020767","Gastrointestinal Disease","5-HT Receptor","Neuronal Signaling","Cisapride (Propulsid, Alimix, Propulsin, Enteropride, Kinestase) acts directly as a selective serotonin 5-HT4 receptor agonist with IC50 of 0.483 μM. And It also acts indirectly as a parasympathomimetic.",483.96,"260779-88-2",96,198.36,"<1",0,"https://www.selleckchem.com/products/cisapride-hydrate.html","C23H29ClFN3O4.H2O","hydrate","Propulsid, Alimix, Propulsin, Enteropride, Kinestase","O.COC1CN(CCCOC2=CC=C(F)C=C2)CCC1NC(=O)C3=CC(=C(N)C=C3OC)Cl",2.578,4,2,9]
["S4752","Corticosterone (NSC-9705)","h11","L1300-19","in 10mM DMSO","DMF",null,null,"Endocrinology","Glucocorticoid Receptor","Endocrinology & Hormones","Corticosterone (NSC-9705, 17-deoxycortisol, 11β,21-dihydroxyprogesterone), the major stress hormone, is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.",346.46,"50-22-6",69,199.16,"<1",0,"http://selleckchem.com/products/corticosterone.html","C21H30O4","free base","17-deoxycortisol, 11β,21-dihydroxyprogesterone","CC12CC(O)C3C(CCC4=CC(=O)CCC34C)C1CCC2C(=O)CO",2.019,2,2,2]
["S4753","Ganoderic acid A","a2","L1300-20","in 10mM DMSO",null,"EP10.4",null,"Others","Immunology & Inflammation related","Immunology & Inflammation","Ganoderic acid A (GAA), a representative active triterpenoid from Ganoderma lucidum, has been reported to exhibit antinociceptive, antioxidative, cytotoxic, hepatoprotective and anticancer activities.",516.67,"81907-62-2",100,193.55,"<1",0,"http://selleckchem.com/products/ganoderic-acid-a.html","C30H44O7","free base","N/A","CC(CC(=O)CC(C)C(O)=O)C1CC(O)C2(C)C3=C(C(=O)CC12C)C4(C)CCC(=O)C(C)(C)C4CC3O",2.775,4,2,6]
["S4754","Betulin","b2","L1300-20","in 10mM DMSO",null,"BP2019;EP9.2",null,"Infection/Inflammation","Fatty Acid Synthase","Metabolism","Betulin (BE, betulinol, betuline, betulinic alcohol), also known as betulinol, betuline, or betulinic alcohol, is a pentacyclic lupane-type triterpenoid naturally distributed in many plants and displays a broad spectrum of biological and pharmacological properties such as anticancer and chemopreventive activity. Betulin (Trochol), is a sterol regulatory element-binding protein (SREBP) inhibitor with an IC50 of 14.5 μM in K562 cell line.",442.72,"473-98-3",22,49.69,"<1",0,"http://selleckchem.com/products/betulin.html","C30H50O2","free base","betulinol, betuline, betulinic alcohol","CC(=C)C1CCC2(CO)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC34C)C12",6.312,0,2,2]
["S4759","p-Coumaric Acid","c2","L1300-20","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cancer","Anti-infection","Microbiology","p-Coumaric acid (4-Hydroxycinnamic acid, P-Hydroxycinnamic acid, 4-Coumaric acid, Trans-p-Coumaric acid, para-Coumaric Acid) is a hydroxy derivative of cinnamic acid found in a variety of edible plants and is reported to have antioxidant, anti-inflammatory, and antimicrobial activity.",164.16,"501-98-4",32,194.93,"<1",0,"http://selleckchem.com/products/p-coumaric-acid.html","C9H8O3","free base","4-Hydroxycinnamic acid, P-Hydroxycinnamic acid, 4-Coumaric acid, Trans-p-Coumaric acid, para-Coumaric Acid","OC(=O)\\C=C\\C1=CC=C(O)C=C1",1.685,1,1,2]
["S4768","Melibiose","d2","L1300-20","in 10mM DMSO","DMF",null,null,"Others","Others","Others","Melibiose (Galalpha1-6Glcbeta) is a nondigestible disaccharide that consists of one galactose and one glucose moiety in an alpha (1-6) glycosidic linkage.",342.3,"585-99-9",68,198.66,0,0,"http://selleckchem.com/products/melibiose.html","C12H22O11","free base","Galalpha1-6Glcbeta","OCC1OC(OCC(O)C(O)C(O)C(O)C=O)C(O)C(O)C1O",-4.538,3,8,8]
["S4769","L-5-Hydroxytryptophan","e2","L1300-20","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Psychotic disorders","Others","Others","5-Hydroxytryptophan (5-HTP, L-oxitriptan), also known as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin.",220.22,"4350-09-8",16,72.65,0,0,"http://selleckchem.com/products/l-5-hydroxytryptophan.html","C11H12N2O3","free base","L-oxitriptan","NC(CC1=C[NH]C2=CC=C(O)C=C12)C(O)=O",-1.554,1,3,3]
["S4772","alpha-Asarone","f2","L1300-20","in 10mM DMSO","CFDA",null,null,"Psychotic disorders","GABA Receptor","Neuronal Signaling","Alpha (α)-asarone (trans-Asarone) is one of the main pharmacologically active compounds present in Acorus calamus Linn (Acoraceae), Acorus tatarinowii Schott (Acoraceae), and Acorus gramineus Solander. It has anticonvulsant, neuroprotective, anxiolytic and nootropic effects.",208.25,"2883-98-9",41,196.88,0,0,"http://selleckchem.com/products/alpha-asarone.html","C12H16O3","free base","trans-Asarone","COC1=CC(=C(\\C=C\\C)C=C1OC)OC",2.734,3,0,4]
["S4779","Menadiol Diacetate","g2","L1300-20","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017",null,"Hematology","Vitamin","Microbiology","Menadiol Diacetate (Vitamin K4, Acetomenaphthone, Kapilin) is a synthetic hydrophilic menadione compound, which is clinically used as hemostasis medicine. It induces caspase-3-related apoptosis pathway via mitochondrial dysfunction and DNA fragmentation.",258.27,"573-20-6",51,197.47,0,0,"http://selleckchem.com/products/menadiol-diacetate.html","C15H14O4","free base","Vitamin K4, Acetomenaphthone, Kapilin","CC(=O)OC1=C2C=CC=CC2=C(OC(C)=O)C(=C1)C",2.759,4,0,4]
["S4783","Benzyl isothiocyanate","h2","L1300-20","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","Antibiotics","Microbiology","Benzyl isothiocyanate (BITC, Benzoylthiocarbimide, Isothiocyanic Acid Benzoyl Ester) is an isothiocyanate originally found in cruciferous vegetables that exhibits immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiogenic, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities.",149.21,"622-78-6",29,194.36,0,0,"http://selleckchem.com/products/benzyl-isothiocyanate.html","C8H7NS","free base","Benzoylthiocarbimide, Isothiocyanic Acid Benzoyl Ester","S=C=NCC1=CC=CC=C1",0,0,0,0]
["S4788","L-α-Phosphatidylcholine","a3","L1300-20","in 10mM DMSO",null,"USP42-NF37",null,"Others","Others","Others","L-α-phosphatidylcholine, a surfactant and a constituent of the liposomal carrier system, has shown hepatoprotection in the various hepatotoxicity model.",0,"8002-43-5",100,10,0,0,"http://selleckchem.com/products/l-alpha-phosphatidylcholine.html","C10H18LNO8PR2",0,"N/A","C[N+](C)(C)CCO[P]([O-])(=O)OCC(COC(=O)[R])OC(=O)[R]",0,0,0,0]
["S4789","5-Acetylsalicylic acid","b3","L1300-20","in 10mM DMSO","EMA",null,"004996,002272,001143,001144,000874,000875","Inflammation/Immunology","Immunology & Inflammation related","Immunology & Inflammation","5-Acetylsalicylic acid (5-acetyl-2-hydroxybenzoic acid) is a nonsteroidal anti-inflammatory drug.",180.16,"13110-96-8",36,199.82,0,0,"http://selleckchem.com/products/5-acetylsalicylic-acid.html","C9H8O4","free base","5-acetyl-2-hydroxybenzoic acid","CC(=O)C1=CC(=C(O)C=C1)C(O)=O",0,0,0,0]
["S4792","N-Acetylneuraminic acid","c3","L1300-20","in 10mM DMSO","DMF","EP8.8,BP2017,IP2010",null,"Infection/Neurological Disease","Others","Others","N-Acetylneuraminic acid (Neu5Ac, NeuAc, Acido aceneuramico, Acide aceneuramique, Acidium aceneuramicum, Sialic acid, NANA) is the predominant sialic acid found in mammalian cells. Sialic acids are negatively charged monosaccharides attached to the end of sugar chains, giving rise to a wide variety of glycoproteins and glycolipids in biological fluids and cell membranes.",309.27,"131-48-6",61,10,0,0,"http://selleckchem.com/products/n-acetylneuraminic-acid.html","C11H19NO9","free base","Neu5Ac, NeuAc, Acido aceneuramico, Acide aceneuramique, Acidium aceneuramicum, Sialic acid","CC(=O)NC1C(O)CC(O)(OC1C(O)C(O)CO)C(O)=O",0,0,0,0]
["S4797","Nicergoline","d3","L1300-20","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,EP9.4,KP Ⅹ,JP17,BP2017",null,"Angiology/Neurological Disease","Adrenergic Receptor","Endocrinology & Hormones","Nicergoline is an ergot derivative used to treat senile dementia and other disorders with vascular origins. It has a selective alpha-1A adrenergic receptor blocking property and also other additional mechanisms of actions.",484.39,"27848-84-6",22,45.42,0,0,"http://selleckchem.com/products/nicergoline.html","C24H26BrN3O3","free base","N/A","COC12CC(COC(=O)C3=CN=CC(=C3)Br)CN(C)C1CC4=C[N](C)C5=CC=CC2=C45",0,0,0,0]
["S4803","Thymidine (NSC 21548)","e3","L1300-20","in 10mM DMSO","DMF,EMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017",null,"Infection","DNA/RNA Synthesis","DNA Damage/DNA Repair","Thymidine (Deoxythymidine, 2'-Deoxythymidine, 5-Methyldeoxyuridine, DThyd, NSC 21548) is a pyrimidine nucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose. As a constituent of DNA, thymidine pairs with adenine in the DNA double helix.",242.23,"50-89-5",48,198.16,0,0,"http://selleckchem.com/products/thymidine.html","C10H14N2O5","free base","Deoxythymidine, 2'-Deoxythymidine, 5-Methyldeoxyuridine, DThyd","CC1=CN(C2CC(O)C(CO)O2)C(=O)NC1=O",0,0,0,0]
["S4812","Ceftizoxime","f3","L1300-20","in 10mM DMSO","FDA,DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,JP17","050560,063294,050589","Infection","Antibiotics","Microbiology","Ceftizoxime is a semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. It is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.",383.4,"68401-81-0",76,198.23,"<1",0,"http://selleckchem.com/products/ceftizoxime.html","C13H13N5O5S2","free base","N/A","CO\\N=C(C(=O)NC1C2SCC=C(N2C1=O)C(O)=O)\\C3=CSC(=N3)N",-0.644,6,2,5]
["S4813","Cefuroxime axetil","g3","L1300-20","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,KP Ⅹ,JP17,BP2017","065043,065069,065118,065126,065135,065166,065190,065308,065323,065359,065496","Infection","Antibiotics,Bacterial","Microbiology","Cefuroxime axetil, a prodrug of the cephalosporin cefuroxime, is a second generation oral cephalosporin antibiotic with in vitro antibacterial activity against several gram-positive and gram-negative organisms.",510.47,"64544-07-6",100,195.9,0,0,"http://selleckchem.com/products/cefuroxime-axetil.html","C20H22N4O10S","free base","N/A","CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(=O)OC(C)OC(C)=O)COC(N)=O)C3=CC=CO3",-0.178,11,2,12]
["S4815","L-Cysteine HCl","h3","L1300-20","in 10mM DMSO","DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017",null,"Metabolic Disease","Others","Others","L-cysteine Hydrochloride, also known as L-CYSTEINE or Cysteine HCL (anhydrous), is classified as a cysteine or a cysteine derivative that increases glutathione levels and is important for lung and brain function and liver detoxification.",157.62,"52-89-1",31,196.68,0,0,"http://selleckchem.com/products/l-cysteine-hcl.html","C3H7NO2S.ClH","hydrochloride","N/A","Cl.NC(CS)C(O)=O",-2.696,1,1,2]
["S4816","Diatrizoate sodium","a4","L1300-20","in 10mM DMSO","FDA,NDC,DMF","USP39-NF34","011245,009561,011386,016403,009561,087075,087725","Diagnosis","Others","Others","Diatrizoate sodium (Amidotrizoate sodium, Hypaque sodium, Triombrin) is an iodinated radiopaque X-ray contrast medium that is used as a diagnostic aid in angiography, urography and radiography.",635.9,"737-31-5",100,157.26,0,0,"http://selleckchem.com/products/diatrizoate-sodium.html","C11H8I3N2O4.Na","sodium","amidotrizoate sodium, Hypaque sodium, Triombrin","[Na+].CC(=O)NC1=C(I)C(=C(I)C(=C1I)NC(C)=O)C([O-])=O",-0.039,2,2,3]
["S4817","Atenolol","b4","L1300-20","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","072304,073025,073026,073315,073316,073317,073318,073352,073353,073457,073475,073476,073542,073543,073676,074052,074056,074099,074101,074120,074126,074127,074265,074499,076900,076907,077443,077877,078210,078254,078512","Cardiovascular Disease/Neurological Disease/Endocrinology","Adrenergic Receptor","Neuronal Signaling","Atenolol (Tenormin, Normiten, Blokium) is a selective β1 receptor antagonist with log Kd values of −6.66±0.05, −5.99±0.14, −4.11±0.07 for binding to the human β1-, β2- and β3-adrenoceptors.",266.34,"29122-68-7",53,198.99,35,131.41,"http://selleckchem.com/products/atenolol.html","C14H22N2O3","free base","Tenormin, Normiten, Blokium","CC(C)NCC(O)COC1=CC=C(CC(N)=O)C=C1",0.669,2,3,8]
["S4819","Saccharin","c4","L1300-20","in 10mM DMSO","DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.7,Ph.Int_6th,JP17,BP2017,IP2010",null,"Others","Others","Others","Saccharin (Benzoic sulfimide, O-Sulfobenzimide, O-Benzoic sulfimide, Saccharimide) is an artificial sweetener with effectively no food energy.",183.18,"81-07-2",36,196.53,0,0,"http://selleckchem.com/products/saccharin.html","C7H5NO3S","free base","Benzoic sulfimide, O-Sulfobenzimide, O-Benzoic sulfimide, Saccharimide","O=C1N[S](=O)(=O)C2=C1C=CC=C2",0.359,3,1,0]
["S4820","Diastase","d4","L1300-20","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17,IP2010",null,"Others","Others","Others","Diastase, a natural enzyme, catalyses the breakdown of starch into maltose.",0,"9000-92-4",26,10,0,0,"http://selleckchem.com/products/diastase.html",0,0,"N/A",0,0,0,0,0]
["S4830","Maltose","e4","L1300-20","in 10mM DMSO","DMF,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17",null,"Hematology","Others","Others","Maltose (Maltobiose, Malt Sugar, Beta-Maltose, D-Maltose), an non-essential nutrient that provides energy, is an intermediate in the intestinal digestion of glycogen and starch, and is found in germinating grains (and other plants and vegetables).",342.3,"69-79-4",68,198.66,0,0,"http://selleckchem.com/products/maltose.html","C12H22O11","free base","Maltobiose, Malt Sugar, Beta-Maltose, D-Maltose","OCC(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)C(O)C=O",-4.538,3,8,8]
["S4831","Piperonyl butoxide","f4","L1300-20","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,BP2017","021043","Others","P450 (e.g. CYP17)","Metabolism","Piperonyl butoxide (PBO, Butacide, Ethanol butoxide, Pyrenone 606,ENT-14250) is a man-made pesticide synergist, working with insect killers to increase their effectiveness.Piperonyl butoxide is an inhibitor of cytochrome P450 monooxygenases(P450s).",338.44,"51-03-6",67,197.97,0,0,"http://selleckchem.com/products/piperonyl-butoxide.html","C19H30O5",0,"Butacide, Ethanol butoxide, Pyrenone 606,ENT-14250","CCCCOCCOCCOCC1=CC2=C(OCO2)C=C1CCC",3.867,5,0,13]
["S4832","Tolmetin","g4","L1300-20","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","073290,073308,073310,073311,073392,073393,073462,073519,073527,073588,074002,074399,074473,074729","Immunology/Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Tolmetin (Tolectin) is a nonsteroidal anti-inflammatory drug of the heterocyclic acetic acid derivative class and also exhibits analgesic and antipyretic activity.",257.28,"26171-23-3",51,198.23,0,0,"http://selleckchem.com/products/tolmetin.html","C15H15NO3","free base","Tolectin","C[N]1C(=CC=C1C(=O)C2=CC=C(C)C=C2)CC(O)=O",3.267,2,0,4]
["S4833","Cefoxitin sodium","h4","L1300-20","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,USP39-NF34","065011,065012,065050,065051,065238,065239,065312,065313,065414,065415,065464,065467","Infection","Antibiotics,Bacterial","Microbiology","Cefoxitin Sodium is the sodium salt form of cefoxitin, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.",449.43,"33564-30-6",89,198.03,89,198.03,"http://selleckchem.com/products/cefoxitin-sodium.html","C16H16N3O7S2.Na","sodium salt","N/A","[Na+].COC1(NC(=O)CC2=CC=CS2)C3SCC(=C(N3C1=O)C([O-])=O)COC(N)=O",-1.151,5,2,8]
["S4834","Propantheline bromide","a5","L1300-20","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,BP2015,JP16","080927,080928,080977,083029,083151,083706,084428,084541,085780,087663,088377","Gastroenterology","AChR","Neuronal Signaling","Propantheline bromide (Pro-Banthine, Neometantyl, Neopepulsan) is a muscarinic antagonist used to treat gastrointestinal conditions associated with intestinal spasm and to decrease secretions during anesthesia.",448.39,"50-34-0",89,198.49,0,0,"http://selleckchem.com/products/propantheline-bromide.html","C23H30NO3.Br","bromide","Pro-Banthine, Neometantyl, Neopepulsan","[Br-].CC(C)[N+](C)(CCOC(=O)C1C2=C(OC3=CC=CC=C13)C=CC=C2)C(C)C",0.763,3,0,7]
["S4835","Aceclofenac","b5","L1300-20","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.3,KP Ⅹ,BP2017,IP2010",null,"Immunology/Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Aceclofenac (Preservex, Airtal) is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties.",354.18,"89796-99-6",70,197.64,0,0,"http://selleckchem.com/products/aceclofenac.html","C16H13Cl2NO4","free base","Preservex, Airtal","OC(=O)COC(=O)CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1",4.08,3,1,7]
["S4836","Nilutamide","c5","L1300-20","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","207631","Cancer/Inflammation","Androgen Receptor","Endocrinology & Hormones","Nilutamide (RU23908) is a nonsteroidal antiandrogen (NSAA) with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors). It is used in the treatment of prostate cancer.",317.22,"63612-50-0",63,198.6,"<1",0,"http://selleckchem.com/products/nilutamide.html","C12H10F3N3O4",0,"RU23908","CC1(C)NC(=O)N(C2=CC=C(C(=C2)C(F)(F)F)[N+]([O-])=O)C1=O",2.254,2,1,3]
["S4837","Ibudilast","d5","L1300-20","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Inflammation","PDE","Metabolism","Ibudilast (KC-404, AV411, MN166) is a relatively non-selective phosphodiesterase inhibitor with anti-inflammatory and neuroprotective activities.",230.31,"50847-11-5",46,199.73,30,130.26,"http://selleckchem.com/products/Ibudilast.html","C14H18N2O","free base","KC-404, AV411, MN166","CC(C)C(=O)C1=C2C=CC=C[N]2N=C1C(C)C",3.339,2,0,3]
["S4838","Acotiamide hydrochloride","e5","L1300-20","in 10mM DMSO","DMF,PMDA",null,null,"Gastrointestinal Disease","AChR","Neuronal Signaling","Acotiamide Hydrochloride (YM-443, Z-338) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. It is a new orally active selective acetylcholinesterase inhibitor.",541.06,"773092-05-0",100,184.82,5,9.24,"http://selleckchem.com/products/acotiamide-hydrochloride.html","C21H30N4O5S.HCl.3H2O","hydrochloride trihydrate","YM-443 HCl, Z-338 HCl","O.O.O.Cl.COC1=CC(=C(C=C1OC)C(=O)NC2=NC(=CS2)C(=O)NCCN(C(C)C)C(C)C)O",2.325,5,3,10]
["S4839","Mosapride","f5","L1300-20","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17,IP2010",null,"Gastrointestinal Disease","5-HT Receptor","Neuronal Signaling","Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.",421.89,"112885-41-3",84,199.1,0,0,"http://selleckchem.com/products/mosapride.html","C21H25ClFN3O3",0,"N/A","CCOC1=CC(=C(Cl)C=C1C(=O)NCC2CN(CCO2)CC3=CC=C(F)C=C3)N",2.932,3,2,7]
["S4841","Laurocapram","g5","L1300-20","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Laurocapram (N-Dodecylcaprolactam, Azone, N-0252, N-Lauryl caprolactam, Tranzone) is a skin penetration enhancer that facilitates absorption of cutaneously applied substances.",281.48,"59227-89-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/laurocapram.html","C18H35NO","free base","N-Dodecylcaprolactam, Azone, N-0252, N-Lauryl caprolactam, Tranzone","CCCCCCCCCCCCN1CCCCCC1=O",5.725,1,0,11]
["S4843","Potassium acetate","h5","L1300-20","in 10mM DMSO","FDA,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","018896,206203","Endocrinology/Metabolic Disease","Fungal","Microbiology","Potassium acetate (Diuretic salt, Potassium ethanoate) is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties.",98.14,"127-08-2",6,61.14,0,0,"http://selleckchem.com/products/potassium-acetate.html","C2H3O2.K","potassium salt","Diuretic salt, Potassium ethanoate","CC(=O)O[K]",-0.114,2,0,1]
["S4844","Cefcapene Pivoxil Hydrochloride","a6","L1300-20","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Infection","Bacterial","Microbiology","Cefcapene Pivoxil is the pivalate ester prodrug form of cefcapene, a semi-synthetic third-generation cephalosporin with antibacterial activity.",622.11,"147816-24-8",100,160.74,0,0,"http://selleckchem.com/products/cefcapene-pivoxil-hydrochloride.html","C23H29N5O8S2.HCl.H2O","hydrochloride, hydrate","N/A","O.Cl.CC\\C=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C)COC(N)=O)C3=CSC(=N3)N",2.027,9,3,13]
["S4845","Rabeprazole","b6","L1300-20","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017","076822,076824,076885,078964,090678,202376,204179,204237,205761,208644","Gastroenterology","Proton Pump","Transmembrane Transporters","Rabeprazole(LY307640) is an oral inhibitor of proton pump and blocks the production of acid by the stomach.",359.44,"117976-89-3",71,197.53,71,197.53,"http://selleckchem.com/products/rabeprazole.html","C18H21N3O3S","free base","LY307640","COCCCOC1=C(C)C(=NC=C1)C[S](=O)C2=NC3=C([NH]2)C=CC=C3",2.366,5,1,8]
["S4846","Meropenem Trihydrate","c6","L1300-20","in 10mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017",null,"Infection","Bacterial","Microbiology","Meropenem is a broad-spectrum antibacterial agent of the carbapenem family with a broad spectrum of in vitro activity against Gram-positive and Gram-negative pathogens.",437.51,"119478-56-7",87,198.85,87,198.85,"http://selleckchem.com/products/meropenem-trihydrate.html","C17H25N3O5S.3H2O","trihydrate","N/A","O.O.O.CC(O)C1C2C(C)C(=C(N2C1=O)C(O)=O)SC3CNC(C3)C(=O)N(C)C",-4.75,3,2,5]
["S4847","Faropenem Sodium","d6","L1300-20","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Infection","Antibiotics","Microbiology","Faropenem sodium is an orally active beta-lactam antibiotic that has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia.",307.3,"122547-49-3",12,39.05,61,198.5,"http://selleckchem.com/products/faropenem-sodium.html","C12H14NO5S.Na","sodium","N/A","[Na+].CC(O)C1C2SC(=C(N2C1=O)C([O-])=O)C3CCCO3",-1.793,2,1,3]
["S4848","Dalbavancin","e6","L1300-20","in 10mM DMSO","FDA,EMA,NDC","Martindale:The Extra Pharmacopoeia","021883","Infection","Antibiotics,Bacterial","Microbiology","Dalbavancin (Zeven, BI 397, MDL 63397) is a lipoglycopeptide antibiotic that has bactericidal activity against Gram-positive bacteria including various staphylococci.",1816.69,"171500-79-1",100,55.05,100,55.05,"http://selleckchem.com/products/dalbavancin.html","C88H100Cl2N10O28","free base","Zeven, BI 397, MDL 63397","CNC1C(=O)NC2CC3=CC=C(OC4=C(OC5OC(C(O)C(O)C5NC(=O)CCCCCCCCC(C)C)C(O)=O)C6=CC(=C4)C(NC(=O)C(NC2=O)C7=CC(=CC(=C7Cl)O)OC8=CC=C1C=C8O)C(=O)NC9C(=O)NC(C(O)C%10=CC(=C(O6)C=C%10)Cl)C(=O)NC(C(=O)NCCCN(C)C)C%11=C(C(=CC(=C%11)O)OC%12OC(CO)C(O)C(O)C%12O)C%13=CC9=CC=C%13O)C=C3",1.865,16,20,22]
["S4849","Levocetirizine Dihydrochloride","f6","L1300-20","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37","090199,090229,090362,090385,090392,090486,091263,091264,201653,202046,202673,202915,203027,203646,204323,204599,205564,210375,211528,211551,211983","Immunology","Histamine Receptor","Neuronal Signaling","Levocetirizine (Xyzal, (-)-Cetirizine) is the active R-enantiomer of cetirizine and represents a new second-generation histamine H1 antagonist.",461.81,"130018-87-0",92,199.22,92,199.22,"http://selleckchem.com/products/levocetirizine-dihydrochloride.html","C21H25ClN2O3.2HCl","dihydrochloride","Xyzal Dihydrochloride, (-)-Cetirizine Dihydrochloride","Cl.Cl.OC(=O)COCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3",1.217,2,0,8]
["S4850","Flucloxacillin sodium","g6","L1300-20","in 10mM DMSO","CFDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,BP2017",null,"Infection","Antibiotics,Bacterial","Microbiology","Flucloxacillin sodium (Floxacillin sodium) is the sodium salt of flucloxacillin, a penicillin antibiotic used to treat bacterial infections.",475.85,"1847-24-1",95,199.64,95,199.64,"http://selleckchem.com/products/flucloxacillin-sodium.html","C19H16ClFN3O5S.Na","sodium salt","Floxacillin sodium","[Na+].CC1=C(C(=O)NC2C3SC(C)(C)C(N3C2=O)C([O-])=O)C(=NO1)C4=C(F)C=CC=C4Cl",1.031,4,1,4]
["S4851","Tafluprost","h6","L1300-20","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA",null,"209040","Ophthalmology","Prostaglandin Receptor","GPCR & G Protein","Tafluprost (AFP-168,MK2452) is a novel prostaglandin analog with a high affinity for the fluoroprostaglandin (FP) receptor PGF2α. A prostanoid selective FP receptor agonist.",452.53,"209860-87-7","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/tafluprost.html","C25H34F2O5",0,"AFP-168,MK2452","CC(C)OC(=O)CCC\\C=C/CC1C(O)CC(O)C1/C=C/C(F)(F)COC2=CC=CC=C2",4.329,3,2,13]
["S4852","Gadopentetate Dimeglumine","a7","L1300-20","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37","019596,021037","Diagnosis","Others","Others","Gadopentetate Dimeglumine (Gadopentetic acid dimeglumine, Gd-DTPA, Meglumine gadopentetate), a complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid, is an extracellular intravenous contrast agent used in magnetic resonance imaging.",938,"86050-77-3",100,106.61,0,0,"http://selleckchem.com/products/gadopentetate-dimeglumine.html","C14H18GdN3O10.2C7H17NO5.2H","dimeglumine salt","Gadopentetic acid dimeglumine, Gd-DTPA, Meglumine gadopentetate","CNCC(O)C(O)C(O)C(O)CO.CNCC(O)C(O)C(O)C(O)CO.OC(=O)CN1CCN2CCN(CC(O)=O)CC(=O)O[Gd](OC(=O)C2)OC(=O)C1",-13.058,8,12,16]
["S4853","Ecabet sodium","b7","L1300-20","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Gastroenterology","ROS","Apoptosis","Ecabet sodium (TA-2711, TA-2711E) is a widely employed mucoprotective agent for the treatment of gastric ulcers. Ecabet sodium inhibits the ability of Helicobacter pylori to induce neutrophil production of reactive oxygen species and interleukin-8, Ecabet sodium can also reduce apoptosis.",402.48,"86408-72-2",80,198.77,16,39.75,"http://selleckchem.com/products/ecabet-sodium.html","C20H27O5S.Na","sodium salt","TA-2711, TA-2711E","[Na+].CC(C)C1=CC2=C(C=C1[S]([O-])(=O)=O)C3(C)CCCC(C)(C3CC2)C(O)=O",2.477,1,0,3]
["S4854","Bedaquiline fumarate","c7","L1300-20","in 10mM DMSO","FDA,DMF,NDC,PMDA",null,"204384","Infection/Respiratory Disease","Bacterial","Microbiology","Bedaquiline fumarate (TMC-207), an oral diarylquinoline,  is a bactericidal antimycobacterial drug. It is a proton-translocating ATP synthetase inhibitor.",671.58,"845533-86-0",100,148.9,"<1",0,"http://selleckchem.com/products/bedaquiline-fumarate.html","C32H31BrN2O2.C4H4O4","fumarate","TMC-207","COC1=C(C=C2C=C(Br)C=CC2=N1)C(C3=CC=CC=C3)C(O)(CCN(C)C)C4=C5C=CC=CC5=CC=C4.OC(=O)\\C=C\\C(O)=O",3.937,4,0,10]
["S4856","Iproniazid","d7","L1300-20","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Infection/Neurological Disease","MAO","Metabolism","Iproniazid (Marsilid, Iprazid) is a non-selective, irreversible monoamine oxidase (MAO) inhibitor (MAOI) that is used as an antidepressive agent.",179.22,"54-92-2",35,195.29,35,195.29,"http://selleckchem.com/products/Iproniazid.html","C9H13N3O","free base","Marsilid, Iprazid","CC(C)NNC(=O)C1=CC=NC=C1",0.121,2,2,3]
["S4859","TriacetonaMine","e7","L1300-20","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","ADC Cytotoxin","Others","TriacetonaMine (Tempidon, Tmpone, Odoratine, Vincubine), a member of the class of compounds known as piperidinones, is an extremely weak acidic compound found in green vegetables and tea.",155.24,"826-36-8",31,199.69,0,0,"http://selleckchem.com/products/triacetonamine.html","C9H17NO","free base","2,2,6,6-Tetramethyl-4-piperidinone; Tempidon; Tmpone; Odoratine; Vincubine","CC1(C)CC(=O)CC(C)(C)N1",0.713,1,1,0]
["S4860","Indole-3-carboxylic acid","f7","L1300-20","in 10mM DMSO",null,"USP42-NF37",null,"Others","Others","Others","Indole-3-carboxylic acid (3-Indoleformic acid, 3-Carboxyindole, β-Indolylcarboxylic acid, 3-indolecarboxylate, 3-indoleformate) is a normal urinary indolic tryptophan metabolite which belongs to a class of organic compounds known as indolecarboxylic acids and derivatives.",161.16,"771-50-6",32,198.56,0,0,"http://selleckchem.com/products/indole-carboxylic-acid.html","C9H7NO2",0,"3-Indoleformic acid, 3-Carboxyindole, β-Indolylcarboxylic acid, 3-indolecarboxylate, 3-indoleformate","OC(=O)C1=C[NH]C2=C1C=CC=C2",1.753,1,1,1]
["S4862","Squalene","g7","L1300-20","in 10mM DMSO","DMF,CFDA,NDC",null,null,"Cardiovascular Disease","Fungal","Microbiology","Squalene (Spinacene, Supraene, trans-Squalene), a naturally occurring substance found in plants, animals and humans, is a component of some adjuvants that is added to vaccines to enhance the immune response.",410.72,"111-02-4","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/squalene.html","C30H50","free base","Spinacene, Supraene, trans-Squalene","CC(C)=CCC\\C(C)=C\\CC\\C(C)=C\\CC\\C=C(C)\\CC\\C=C(C)\\CCC=C(C)C",11.331,0,0,15]
["S4865","Cefetamet pivoxil hydrochloride","h7","L1300-20","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Infection","Antibiotics","Microbiology","Cefetamet pivoxil hydrochloride is the hydrochloride salt form of cefetamet pivoxil, which is an oral third-generation cephalosporin antibiotic.",548.03,"111696-23-2",100,182.47,"<1",0,"http://selleckchem.com/products/cefetamet-pivoxil-hydrochloride.html","C20H25N5O7S2.HCl","hydrochloride","N/A","Cl.CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C)C)C3=CSC(=N3)N",1.778,9,2,10]
["S4866","Nicarbazin","a8","L1300-20","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Parasite","Parasite","Microbiology","Nicarbazin, an effective anticoccidial, is also a wide-spectrum anti-parasitic drug.",426.38,"330-95-0",9,21.11,"<1",0,"http://selleckchem.com/products/nicarbazin.html","C13H10N4O5.C6H8N2O","salt","N/A","CC1=NC(=NC(=C1)C)O.[O-][N+](=O)C2=CC=C(NC(=O)NC3=CC=C(C=C3)[N+]([O-])=O)C=C2",3.207,3,3,4]
["S4867","Propacetamol hydrochloride","b8","L1300-20","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017",null,"Neurological Disease","Others","Others","Propacetamol hydrochloride (PRO) is a water-soluble prodrug of paracetamol (PA) which can be parenterally administered as analgesic for the treatment of postoperative pain, acute trauma, and gastric and/or intestinal disorders.",300.78,"66532-86-3",60,199.48,60,199.48,"http://selleckchem.com/products/propacetamol-hydrochloride.html","C14H20N2O3.HCl","hydrochloride","N/A","Cl.CCN(CC)CC(=O)OC1=CC=C(NC(C)=O)C=C1",1.803,3,1,7]
["S4868","Xanthinol Nicotinate","c8","L1300-20","in 10mM DMSO","CFDA",null,null,"Angiology","Others","Others","Xanthinol Nicotinate (Complamin, Angioamin) is a potent vasodilator that can easily pass through the cell membrane and once inside the cell it causes an increase in glucose metabolism resulting in an increased energy.",434.45,"437-74-1",24,55.24,0,0,"http://selleckchem.com/products/xanthinol-nicotinate.html","C13H21N5O4.C6H5NO2","Nicotinate","Complamin, Angioamin","CN(CCO)CC(O)C[N]1C=NC2=C1C(=O)N(C)C(=O)N2C.OC(=O)C3=CC=CN=C3",-3.737,5,2,7]
["S4869","Sulfamethoxazole sodium","d8","L1300-20","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,KP Ⅹ,EP9.2,Ph.Int_6th,JP17,BP2017","085053,085844,086000,086163,087189,087662","Infection/Inflammation","Antibiotics,Bacterial","Microbiology","Sulfamethoxazole sodium is an antibiotic used for bacterial infections.",275.26,"4563-84-2",55,199.81,0,0,"http://selleckchem.com/products/sulfamethoxazole-sodium.html","C10H10N3O3S.Na","sodium","N/A","CC1=CC(=NO1)N([Na])[S](=O)(=O)C2=CC=C(N)C=C2",0.813,4,1,3]
["S4870","Cefodizime Sodium","e8","L1300-20","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Infection","Antibiotics","Microbiology","Cefodizime Sodium, a third generation cephalosporin antibiotic, has broad-spectrum activity and is stable to most beta-lactamases.",628.63,"86329-79-5",100,159.08,0,0,"http://selleckchem.com/products/cefodizime-sodium.html","C20H18N6O7S4.2Na","disodium salt","N/A","[Na+].[Na+].CO/N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)CSC3=NC(=C(CC([O-])=O)S3)C)C4=CSC(=N4)N",-2.271,6,2,10]
["S4871","Pyridoxal 5-phosphate monohydrate","f8","L1300-20","in 10mM DMSO","DMF","USP42-NF37",null,"Nutritional support","Vitamin","Metabolism","Pyridoxal 5-phosphate monohydrate is an active vitamin B6 metabolite, which is a cofactor in many reactions of amino acid metabolism.",265.16,"41468-25-1",22,82.97,0,0,"http://selleckchem.com/products/pyridoxal-phosphate-monohydrate.html","C8H10NO6P.H2O","hydrate","N/A","O.CC1=NC=C(CO[P](O)(O)=O)C(=C1O)C=O",-0.404,3,1,4]
["S4874","Cefazedone","g8","L1300-20","in 10mM DMSO","CFDA",null,null,"Infection","Bacterial","Microbiology","Cefazedone (Refosporen, Cefazedonum) is a semisynthetic first-generation cephalosporin with antibacterial activity.",548.44,"56187-47-4",100,182.34,0,0,"http://selleckchem.com/products/cefazedone.html","C18H15Cl2N5O5S3","free base","Refosporen, Cefazedonum","CC1=NN=C(SCC2=C(N3C(SC2)C(NC(=O)CN4C=C(Cl)C(=O)C(=C4)Cl)C3=O)C(O)=O)S1",0.149,6,1,7]
["S4875","Cephapirin Benzathine","h8","L1300-20","in 10mM DMSO","DMF","USP42-NF37",null,"Infection","Bacterial","Microbiology","Cephapirin Benzathine is the benzathine salt form of cephapirin, which is a semisynthetic, broad-spectrum, first-generation cephalosporin with antibacterial activity.",1087.27,"97468-37-6",81,74.5,0,0,"http://selleckchem.com/products/cephapirin-benzathine.html","C50H54N8O12S4","salt","N/A","CC(=O)OCC1=C(N2C(SC1)C(NC(=O)CSC3=CC=NC=C3)C2=O)C(O)=O.CC(=O)OCC4=C(N5C(SC4)C(NC(=O)CSC6=CC=NC=C6)C5=O)C(O)=O.C(CNCC7=CC=CC=C7)NCC8=CC=CC=C8",-3.531,12,4,23]
["S4876","Robenidine Hydrochloride","a9","L1300-20","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Infection/Parasite","Parasite","Microbiology","Robenidine Hydrochloride (Dexium, Nugatex, Rasexinium, Toraxine) is an anticoccidial agent mainly for poultry.",370.66,"25875-50-7",74,199.64,0,0,"http://selleckchem.com/products/robenidine-hydrochoride.html","C15H13Cl2N5.HCl","hydrochloride","Dexium, Nugatex, Rasexinium, Toraxine","Cl.ClC1=CC=C(C=C1)\\C=N\\NC(=N)N\\N=C\\C2=CC=C(Cl)C=C2",4.425,2,2,6]
["S4877","Eperisone hydrochloride","b9","L1300-20","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Neurological Disease","Others","Others","Eperisone hydrochloride is muscle relaxant agent with antispasmodic effects. It is widely used in the treatment of patients with muscular contractures, low back pain or spasticity.",295.85,"56839-43-1",59,199.43,0,0,"http://selleckchem.com/products/eperisone-hydrochloride.html","C17H25NO.HCl","hydrochloride","N/A","Cl.CCC1=CC=C(C=C1)C(=O)C(C)CN2CCCCC2",4.528,1,0,5]
["S4878","Neticonazole Hydrochloride","c9","L1300-20","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia",null,"Infection","Fungal","Microbiology","Neticonazole is an imidazole antifungal for the treatment of fungal skin infections.",338.9,"130773-02-3",67,197.7,0,0,"http://selleckchem.com/products/neticonazole-hydrochloride.html","C17H22N2OS.HCl","hydrochloride","N/A","Cl.CCCCCOC1=CC=CC=C1C(=C\\SC)/[N]2C=CN=C2",3.838,2,0,8]
["S4880","Cefathiamidine","d9","L1300-20","in 10mM DMSO","CFDA",null,null,"Infection","Bacterial","Microbiology","Cefathiamidine is the first generation of cephalosporin antibacterial used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis.",472.58,"33075-00-2",94,198.91,0,0,"http://selleckchem.com/products/cefathiamidine.html","C19H28N4O6S2","free base","N/A","CC(C)NC(SCC(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)COC(C)=O)=NC(C)C",0.729,6,2,11]
["S4881","Calcium Dobesilate","e9","L1300-20","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,EP9.1, BP2017",null,"Angiology/Gastroenterology","Others","Apoptosis","Calcium dobesilate (calcium dihydroxy-2,5-benzenesulfonate) is a small molecule that has been widely used for treating diabetic retinopathy and chronic venous insufficiency.",209.2,"20123-80-2",41,195.98,0,0,"http://selleckchem.com/products/calcium-dobesilate.html","C6H5O5S.1/2Ca","Dobesilate","calcium dihydroxy-2,5-benzenesulfonate","OC1=CC=C(O)C(=C1)[S]([O-])(=O)=O",-0.832,0,2,1]
["S4883","Lynestrenol","f9","L1300-20","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Lynestrenol (Ethinylestrenol) is a synthetic progestational hormone, an agonist of the progesterone receptor and has weak androgenic and estrogenic activity.",284.44,"52-76-6",56,196.88,0,0,"http://selleckchem.com/products/lynestrenol.html","C20H28O","free base","Ethinylestrenol","CC12CCC3C(CCC4=CCCCC34)C1CCC2(O)C#C",5.316,0,0,0]
["S4885","Taurolidine","g9","L1300-20","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Cancer/Infection","Antibiotics,Bacterial","Microbiology","Taurolidine (Taurolin, Tauroline, Tauroflex) is a synthetic broad-spectrum antibiotic with antibacterial, anticoagulant and potential antiangiogenic activities.",284.36,"19388-87-5",56,196.93,0,0,"http://selleckchem.com/products/taurolidine.html","C7H16N4O4S2","free base","Taurolin, Tauroline, Tauroflex","O=[S]1(=O)CCN(CN1)CN2CC[S](=O)(=O)NC2",-1.991,4,2,2]
["S4886","Menbutone","h9","L1300-20","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Gastroenterology/Metabolic Disease","Others","Others","Menbutone (Genabilin, Naftobil, Genabilic acid), or genabilic acid, is a derivative of oxybutyric acid which acts as a choleretic stimulating secretion, a trypsinogen and a pepsinogen.",258.27,"3562-99-0",51,197.47,0,0,"http://selleckchem.com/products/menbutone.html","C15H14O4",0,"Genabilin, Naftobil, Genabilic acid","COC1=C2C=CC=CC2=C(C=C1)C(=O)CCC(O)=O",2.307,3,0,5]
["S4889","Perospirone hydrochloride","a10","L1300-20","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia",null,"Psychotic disorders","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Perospirone (SM-9018) is an atypical or second-generation antipsychotic of the azapirone family that antagonizes serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist.",463.04,"129273-38-7",92,198.69,0,0,"http://selleckchem.com/products/perospirone-hydrochloride.html","C23H30N4O2S.HCl","hydrochloride","SM-9018 hydrochloride","Cl.O=C1C2CCCCC2C(=O)N1CCCCN3CCN(CC3)C4=NSC5=C4C=CC=C5",4.423,3,0,6]
["S4890","Bifendate","b10","L1300-20","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Others","Reverse Transcriptase","Microbiology","Bifendate, a synthetic intermediate of schisandrin C, is an anti-HBV drug used in Chinese medicine for the treatment of chronic hepatitis B.",418.35,"73536-69-3",83,198.4,0,0,"http://selleckchem.com/products/bifendate.html","C20H18O10","free base","N/A","COC(=O)C1=CC(=C2OCOC2=C1C3=C(C=C(OC)C4=C3OCO4)C(=O)OC)OC",2.562,10,0,7]
["S4893","Cytosine","c10","L1300-20","in 10mM DMSO","DMF","EP9.2,BP2015",null,"Others","Others","Others","Cytosine (4-Amino-2-hydroxypyrimidine, Cytosinimine) is one of the four main bases found in DNA and RNA used in storing and transporting genetic information within a cell.",111.1,"71-30-7",10,90.01,0,0,"http://selleckchem.com/products/cytosine.html","C4H5N3O","free base","4-Amino-2-hydroxypyrimidine, Cytosinimine","NC1=NC(=O)NC=C1",-0.958,2,2,0]
["S4894","D-Glucurone","d10","L1300-20","in 10mM DMSO","NMPA",null,null,"Metabolism","Others","Others","D-Glucurone is a glucuronic acid derivative that is used for treating canine hepatitis.",176.12,"32449-92-6",35,198.73,0,0,"http://selleckchem.com/products/d-glucurone.html","C6H8O6","free base","N/A","OC1OC2C(O)C(=O)OC2C1O",-1.803,3,2,0]
["S4896","Elagolix Sodium","e10","L1300-20","in 10mM DMSO","FDA",null,"210450","Cancer/Endocrinology","GNRH Receptor","Endocrinology & Hormones","Elagolix Soidum (NBI-56418, ABT-620) is a potent, selective, orally active, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with Kd value of 54 pM. Concentration at 10 μM shows no significant activity on ion channels, enzymes, and transporters (inhibition <50%).",653.57,"832720-36-2",100,153.01,100,153.01,"http://selleckchem.com/products/elagolix-sodium.html","C32H29F5N3O5.Na","sodium","NBI-56418, ABT-620","[Na+].COC1=C(F)C(=CC=C1)C2=C(C)N(CC3=C(F)C=CC=C3C(F)(F)F)C(=O)N(CC(NCCCC([O-])=O)C4=CC=CC=C4)C2=O",4.104,3,1,13]
["S4899","Sulfogaiacol","f10","L1300-20","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Respiratory Disease","Others","Others","Sulfogaiacol (Guaiacolsulfonate) is a antitussive agent that is used for acute respiratory tract infections, cough and other conditions.",242.29,"1321-14-8",48,198.11,0,0,"http://selleckchem.com/products/sulfogaiacol.html","C7H7O5S.K",0,"Guaiacolsulfonate","[K+].COC1=CC(=CC=C1O)[S]([O-])(=O)=O",-1.341,1,1,2]
["S4931","Propiverine hydrochloride","g10","L1300-20","in 10mM DMSO","CFDA,,PMDA,HMA","Martindale:The Extra Pharmacopoeia,JP17",null,"Others","AChR,Calcium Channel","Transmembrane Transporters","Propiverine is an anticholinergic drug used for the treatment of overactive bladder and urinary incontinence. Propiverine is a muscarinic receptor antagonist possessing additional properties, i.e., block of L-type Ca2+ channels.",403.94,"54556-98-8",80,198.05,0,0,"http://selleckchem.com/products/propiverine-hydrochloride.html","C23H29NO3.ClH","HCl","N/A","Cl.CCCOC(C(=O)OC1CCN(C)CC1)(C2=CC=CC=C2)C3=CC=CC=C3",4.388,3,0,8]
["S4932","Proxyphylline","h10","L1300-20","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017",null,"Angiology/Cardiovascular Disease","Adenosine Receptor","GPCR & G Protein","Proxyphylline (Monophylline, Spasmolysin) is a derivative of theophylline which is used as a bronchodilator and for its cardiovascular properties. It selectively antagonizes A1 adenosine receptors (Ki = 82 nM for bovine brain) versus A2 adenosine receptors (Ki = 850 µM for platelets).",238.24,"603-00-9",47,197.28,0,0,"http://selleckchem.com/products/proxyphylline.html","C10H14N4O3","free base","Monophylline, Spasmolysin","CC(O)C[N]1C=NC2=C1C(=O)N(C)C(=O)N2C",-0.262,3,1,2]
["S4935","Asunaprevir (BMS-650032)","a11","L1300-20","in 10mM DMSO","PMDA",null,null,"Infection","HCV Protease","Proteases","Asunaprevir (BMS-650032) is an orally bioavailable inhibitor of the hepatitis C virus enzyme serine protease NS3 that is necessary for protein processing required for viral replication.",748.29,"630420-16-5",100,133.64,"<1",0,"http://selleckchem.com/products/asunaprevir.html","C35H46ClN5O9S","free base","BMS-650032","COC1=C2C=CC(=CC2=C(OC3CC(N(C3)C(=O)C(NC(=O)OC(C)(C)C)C(C)(C)C)C(=O)NC4(CC4C=C)C(=O)N[S](=O)(=O)C5CC5)N=C1)Cl",3.565,10,3,14]
["S4939","cis-Aconitic acid","b11","L1300-20","in 10mM DMSO","NDC",null,null,"Others","Others","Others","Cis-Aconitic acid (cis-aconitate, Achilleic acid, Citridinic acid, Equisetic acid, Pyrocitric acid) is an intermediate in the tricarboxylic acid cycle produced by the dehydration of citric acid.",174.11,"585-84-2",34,195.28,0,0,"http://selleckchem.com/products/cis-aconitic-acid.html","C6H6O6","free base","cis-aconitate, Achilleic acid, Citridinic acid, Equisetic acid, Pyrocitric acid","OC(=O)CC(=C/C(O)=O)/C(O)=O",-0.337,3,0,4]
["S4940","Maltol","c11","L1300-20","in 10mM DMSO","EMA","USP42-NF37",null,"Others","Antioxidant","PI3K/Akt/mTOR","Maltol (Larixinic acid, Palatone, Veltol) is a naturally occurring organic compound that is flavour enhancer and flavouring agent.",126.11,"118-71-8",25,198.24,0,0,"http://selleckchem.com/products/maltol.html","C6H6O3",0,"Larixinic acid, Palatone, Veltol","CC1=C(O)C(=O)C=CO1",-0.222,2,1,0]
["S4941","Farnesol","d11","L1300-20","in 10mM DMSO",null,"EP10.4",null,"Others","Antibiotics","Microbiology","Farnesol is a natural sesquiterpene alcohol that is potent in treating antimetabolic disorders, anti-inflammation, showing antioxidant, anticancer, and antibiotic effects.",222.37,"4602-84-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/farnesol.html","C15H26O","free base","N/A","CC(C)=CCCC(/C)=C/CCC(/C)=C/CO",4.76,0,1,7]
["S4949","Nonanoic acid","e11","L1300-20","in 10mM DMSO",null,"USP42-NF37",null,"Others","Others","Others","Nonanoic acid (Pelargonic acid, Nonoic acid) is a naturally occurring fatty acid found in both vegetable and animal fats.",158.24,"112-05-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/nonanoic-acid.html","C9H18O2","free base","Pelargonic acid, Nonoic acid","CCCCCCCCC(O)=O",3.199,1,0,7]
["S4952","Fumaric acid","f11","L1300-20","in 10mM DMSO","NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010",null,"Immunology","Others","Others","Fumaric acid (Fumarate, 2-Butenedioic acid, Trans-Butenedioic acid) is an intermediate in the citric acid cycle used by cells to produce energy in the form of adenosine triphosphate (ATP) from food; also a product of the urea cycle.",116.07,"110-17-8",23,198.16,0,0,"http://selleckchem.com/products/fumaric-acid.html","C4H4O4","free base","2-Butenedioic acid, Trans-Butenedioic acid, Allomaleic acid, Boletic acid, Donitic acid, Lichenic acid, Fumarate","OC(=O)\\C=C\\C(O)=O",0.038,2,0,2]
["S4953","Usnic acid","g11","L1300-20","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cancer","Akt,ERK","PI3K/Akt/mTOR","Usnic acid (Usniacin) is a furandione found uniquely in lichen that is used widely in cosmetics, deodorants, toothpaste and medicinal creams as well as some herbal products. It exhibits antiviral, antiprotozoal, antiproliferative, anti-inflammatory and analgesic activity. Usnic acid inhibits breast tumor angiogenesis and growth by suppressing VEGFR2-mediated AKT and ERK1/2 signaling pathways.",344.32,"125-46-2",4,11.62,0,0,"http://selleckchem.com/products/usnic-acid.html","C18H16O7","free base","Usniacin","CC(=O)C1C(=O)C=C2OC3=C(C(=C(C)C(=C3C(C)=O)O)O)C2(C)C1=O",1.084,5,2,2]
["S4956","Benzamidine HCl","h11","L1300-20","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Others","Serine/threonin kinase","Proteases","Benzamidine is an inhibitor of serine proteases with Ki values of 35, 350, and 220 µM for trypsin, plasmin, and thrombin, respectively.",156.61,"1670-14-0",31,197.94,31,197.94,"http://www.selleck.cn/products/benzamidine-hcl.html","C7H9ClN2","HCl","N/A","Cl.NC(=N)C1=CC=CC=C1",1.268,0,1,1]
["S4957","Linalool","a2","L1300-21","in 10mM DMSO",null,"USP42-NF37;BP2019",null,"Infection/Neurological Disease","NMDAR","Neuronal Signaling","Linalool (Phantol), a monoterpene compound commonly found as major component of essential oils of several aromatic species, is a competitive antagonist of NMDA receptors.",154.25,"78-70-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/linalool.html","C10H18O","free base","Phantol","CC(C)=CCCC(C)(O)C=C",2.735,0,0,4]
["S4958","Glycocholic acid","b2","L1300-21","in 10mM DMSO","DMF",null,null,"Others","Others","Others","Glycocholic acid (Cholylglycine, Glycocholate) is a natural secondary bile acid involved in the emulsification of fats.",465.62,"475-31-0",93,199.73,0,0,"http://selleckchem.com/products/glycocholic-acid.html","C26H43NO6","free base","Cholylglycine, Glycocholate","CC(CCC(=O)NCC(O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CC(O)C12C",1.972,2,4,6]
["S4964","Lactobionic acid","c2","L1300-21","in 10mM DMSO",null,"EP9.2;BP2017",null,"Others","MMP","Proteases","Lactobionic acid (Galactosylgluconic acid), an α-hydroxyacid (AHA) with antioxidation activity, is used in the development of cosmeceuticals for skin. Lactobionic acid inhibits matrix-metalloproteinase (MMP) activity.",358.3,"96-82-2",71,198.16,0,0,"http://selleckchem.com/products/lactobionic-acid.html","C12H22O12",0,"Galactosylgluconic acid","OCC(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)C(O)C(O)=O",-4.56,3,8,8]
["S4969","Tropine","d2","L1300-21","in 10mM DMSO",null,"USP43-NF38",null,"Others","Others","Others","Tropine (Pseudotropine, 3alpha-Tropanol) is a naturally occurring tropane alkaloid that serves as an intermediate in the synthesis of a variety of bioactive alkaloids, many of which have potent neurological actions.",141.21,"120-29-6",28,198.29,0,0,"http://selleckchem.com/products/tropine.html","C8H15NO","free base","Pseudotropine, 3alpha-Tropanol","CN1C2CCC1CC(O)C2",0.271,0,1,0]
["S4971","Buparvaquone","e2","L1300-21","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Parasite","Anti-infection","Microbiology","Buparvaquone (Butalex) is a second-generation hydroxynaphthoquinone related to parvaquone, with novel features that make it a promising compound for the therapy and prophylaxis of all forms of theileriosis.",326.43,"88426-33-9",65,199.12,"<1",0,"http://selleckchem.com/products/buparvaquone.html","C21H26O3","free base","Butalex","CC(C)(C)C1CCC(CC1)CC2=C(O)C(=O)C3=C(C=CC=C3)C2=O",4.993,2,1,3]
["S4973","Iminostilbene","f2","L1300-21","in 10mM DMSO","DMF",null,null,"Others","Others","Others","Iminostilbene (2,3,6,7-Dibenzazepine) is a chemical precursor of carbamazepine which is used primarily in the treatment of epilepsy and neuropathic pain.",193.24,"256-96-2",38,196.65,0,0,"http://selleckchem.com/products/iminostilbene.html","C14H11N","free base","2,3,6,7-Dibenzazepine","N1C2=C(C=CC=C2)C=CC3=CC=CC=C13",3.536,0,1,0]
["S4975","Fimasartan","g2","L1300-21","in 10mM DMSO","marketed in South Korea",null,null,"Cardiovascular Disease","Angiotensin Receptor","GPCR & G Protein","Fimasartan (Kanarb) is a non-peptide angiotensin II receptor antagonist (ARB) with noncompetitive, insurmountable binding with the AT1 receptor. It is used for the treatment of hypertension and heart failure.",501.65,"247257-48-3",100,199.34,0,0,"http://selleckchem.com/products/fimasartan.html","C27H31N7OS","free base","Kanarb","CCCCC1=NC(=C(CC(=S)N(C)C)C(=O)N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=N[NH]4)C",4.515,5,1,10]
["S4976","Sulfalene (SMPZ)","h2","L1300-21","in 10mM DMSO","CFDA",null,null,"Infection/Parasitology","Others","Others","Sulfalene (SMPZ, Butadiene sulfone, 3-Sulfolene) is a cyclic organic chemical used as a versatile synthetic intermediate.",280.3,"152-47-6",56,199.79,"<1",0,"http://selleckchem.com/products/sulfalene-smpz.html","C11H12N4O3S","free base","Butadiene sulfone, 3-Sulfolene","COC1=C(N[S](=O)(=O)C2=CC=C(N)C=C2)N=CC=N1",0.331,5,2,4]
["S4977","Efonidipine","a3","L1300-21","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Efonidipine (NZ-105) is an L- and T-type calcium channel blocker leading to vasodilation and decreased automaticity of the heart. It also suppresses aldosterone secretion from the adrenal.",631.66,"111011-63-3",100,158.31,0,0,"http://selleckchem.com/products/efonidipine.html","C34H38N3O7P","free base","NZ-105","CC1=C(C(C2=CC(=CC=C2)[N+]([O-])=O)C(=C(C)N1)[P]3(=O)OCC(C)(C)CO3)C(=O)OCCN(CC4=CC=CC=C4)C5=CC=CC=C5",4.956,4,1,11]
["S4978","Azathramycin","b3","L1300-21","in 10mM DMSO","DMF",null,null,"Infection","Antibiotics","Microbiology","Azathramycin (Azaerythromycin A, Azaerythromycin) is a macrolide antibiotic containing cladinose.",734.96,"76801-85-9",50,68.03,"<1",0,"http://selleckchem.com/products/azathramycin.html","C37H70N2O12",0,"Azaerythromycin A, Azaerythromycin","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)CNC(C)C(O)C1(C)O",1.542,7,4,7]
["S4980","Anamorelin","c3","L1300-21","in 10mM DMSO","DMF,EMA",null,null,"Cancer","GHSR","GPCR & G Protein","Anamorelin (ONO-7643, RC-1291, ST-1291) is an orally active, high-affinity, selective agonist of the ghrelin receptor with an EC50 value of 0.74 nM in the HEK293/GRLN  FLIPR assay.",546.7,"249921-19-5",100,182.92,"<1",0,"http://selleckchem.com/products/anamorelin.html","C31H42N6O3","free base","ONO-7643, RC-1291, ST-1291","CN(C)N(C)C(=O)C1(CCCN(C1)C(=O)C(CC2=C[NH]C3=C2C=CC=C3)NC(=O)C(C)(C)N)CC4=CC=CC=C4",2.447,3,3,9]
["S4983","Sorbic acid","d3","L1300-21","in 10mM DMSO",null,"EP9.2;BP2017;USP40-NF35;IP2010;Martindale:The Extra Pharmacopoeia",null,"Others","Bacterial","Microbiology","Sorbic acid (2,4-Hexadienoic acid) is a naturally occurring compound that originated from the unripe berries of the Rowan Tree. It inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division).",112.13,"110-44-1",22,196.2,"<1",0,"http://selleckchem.com/products/sorbic-acid.html","C6H8O2","free base","2,4-Hexadienoic acid","C/C=C/C=C/C(O)=O",1.363,1,0,2]
["S4988","Tiamulin fumarate","e3","L1300-21","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017",null,"Infection","Ribosomal Peptidyl Transferase","Microbiology","Tiamulin fumarate is a semisynthetic pleuromutilin antibiotic that binds to the ribosomal peptidyl transferase centre and inhibits protein synthesis.",609.81,"55297-96-6",100,163.99,100,163.99,"http://selleckchem.com/products/tiamulin-fumarate.html","C28H47NO4S.C4H4O4","fumarate","N/A","CCN(CC)CCSCC(=O)OC1CC(C)(C=C)C(O)C(C)C23CCC(C)C1(C)C2C(=O)CC3.OC(=O)\\C=C\\C(O)=O",1.366,5,1,12]
["S4991","Valpromide","f3","L1300-21","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Epoxide Hydrolase","Metabolism","Valpromide (Depamide, Dipropylacetamide, 2-propylpentanamide) is an antiepileptic drug, derivative of Valproic acid (VPA), used as a mood-stabilizer in bipolar disorder. Valpromide inhibits both viral and cellular gene expression. Valpromide is a human epoxide hydrolase inhibitor.",143.23,"2430-27-5",28,195.49,0,0,"http://selleckchem.com/products/valpromide.html","C8H17NO","free base","Depamide, Dipropylacetamide, 2-propylpentanamide","CCCC(CCC)C(N)=O",2.122,1,1,5]
["S4994","Methylcobalamin","g3","L1300-21","in 10mM DMSO","DMF,CFDA,NDC","USP42-NF37",null,"Metabolic Disease","Vitamin","Metabolism","Methylcobalamin (Mecobalamin, Vancomin, Methycobal, Cobametin) is one active form of vitamin B12 which can directly participate in homocysteine metabolism. It is used to treat some nutritional diseases and other diseases in clinic, such as Alzheimer's disease and rheumatoid arthritis.",1344.38,"13422-55-4",100,74.38,0,0,"http://selleckchem.com/products/methylcobalamin.html","C63H91CoN13O14P","inner salt","Mecobalamin, Vancomin, Methycobal, Cobametin","C[Co+]N1\\C2=C(C)/C3=N\\C(=C/C4=NC(=C(C)/C5=NC(C(CC(N)=O)C5(C)CCC(=O)NCC(C)O[P]([O-])(=O)OC6C(O)C(OC6CO)[N]7C=NC8=C7C=C(C)C(=C8)C)C1(C)C(C)(CC(N)=O)C2CCC(N)=O)\\C(CCC(N)=O)C4(C)C)C(CCC(N)=O)C3(C)CC(N)=O",-0.736,14,9,27]
["S4996","Tavaborole (AN-2690)","h3","L1300-21","in 10mM DMSO","FDA,DMF,NDC",null,"204427","Infection","Fungal","Microbiology","Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity.",151.93,"174671-46-6",30,197.46,"<1",0,"http://selleckchem.com/products/tavaborole-an-2690.html","C7H6BFO2","free base","N/A","OB1OCC2=CC(=CC=C12)F",2.305,1,0,0]
["S4999","Avermectin B1","a4","L1300-21","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Parasite","Parasite","Microbiology","Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic.",873.08,"71751-41-2",100,114.54,0,0,"http://selleckchem.com/products/avermectin.html","C48H72O14",0,"abamectin","CCC(C)C1OC2(CC3CC(C\\C=C(C)\\C(OC4CC(OC)C(OC5CC(OC)C(O)C(C)O5)C(C)O4)C(C)\\C=C\\C=C\\6COC7C(O)C(=CC(C(=O)O3)C67O)C)O2)C=CC1C",4.692,11,2,8]
["S5001","Tofacitinib (CP-690550) Citrate","b4","L1300-21","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"203214,208246","Immunology/Inflammation","Anti-infection,JAK","JAK/STAT","Tofacitinib citrate (CP-690550, Tasocitinib) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively. Tofacitinib citrate has anti-infection activity.",504.49,"540737-29-9",100,198.22,"<1",0,"http://selleckchem.com/products/CP-690550.html","C16H20N6O.C6H8O7","Citrate","Tasocitinib Citrate,CP-690550","CC1CCN(CC1N(C)C2=C3C=C[NH]C3=NC=N2)C(=O)CC#N.OC(=O)CC(O)(CC(O)=O)C(O)=O",0.193,6,1,8]
["S5002","Fingolimod (FTY720) HCl","c4","L1300-21","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8","207939,207941,207945,207965,207971,207979,207983,207985,207991,207994,208001,208004,208008,208559,210252","Cancer","S1P Receptor","GPCR & G Protein","Fingolimod (FTY720, Fingolimod Hydrochloride) HCl is a S1P antagonist with IC50 of 0.033 nM in K562, and NK cells.",343.9,"162359-56-0",69,200.64,69,200.64,"http://selleckchem.com/products/FTY720.html","C19H33NO2.HCl","Hydrochloride","Fingolimod Hydrochloride,FTY720","Cl.CCCCCCCCC1=CC=C(CCC(N)(CO)CO)C=C1",4.58,0,3,12]
["S5003","Tacrolimus (FK506)","d4","L1300-21","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,JP17","065461,090402,090509,090596,090687,090802,091195,200744,203900,206651,210393,211688","Immunology","Autophagy,FKBP,phosphatase","PI3K/Akt/mTOR","Tacrolimus (FK506, FR900506, Fujimycin, Prograf) is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex. Tacrolimus also inhibits the phosphatase activity of calcineurin. Tacrolimus induces vascular endothelial autophagy.",804.02,"104987-11-3",94,116.91,"<1",0,"http://selleckchem.com/products/FK-506-(Tacrolimus).html","C44H69NO12","free base","FK506, FR900506, Fujimycin, Prograf","COC1CC(CCC1O)\\C=C(C)\\C2OC(=O)C3CCCCN3C(=O)C(=O)C4(O)OC(C(CC(C)C/C(=C/C(CC=C)C(=O)CC(O)C2C)C)OC)C(CC4C)OC",4.832,9,2,7]
["S5004","Pimecrolimus","e4","L1300-21","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia",209345,"Immunology/Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Pimecrolimus (Elidel,ASM 981,SDZ-ASM 981) is an immunophilin ligand, which binds specifically to the cytosolic receptor, immunophilin macrophilin-12 (FKBP-12); a calcineurin inhibitor.",810.45,"137071-32-0",100,123.39,"<1",0,"http://selleckchem.com/products/Pimecrolimus.html","C43H68ClNO11","free base","Elidel,SDZ-ASM 981","CCC1/C=C(C)/CC(C)CC(OC)C2OC(O)(C(C)CC2OC)C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)C(O)CC1=O)/C(C)=C/C4CCC(Cl)C(C4)OC",5.971,9,1,6]
["S5005","Cefotiam hydrochloride","f4","L1300-21","in 10mM DMSO","FDA,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,JP17,","050601","Infection","Anti-infection","Microbiology","Cefotiam hydrochloride (Halospor, Pansporin, Pansporine) is the hydrochloride salt form of cefotiam and has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.",598.55,"66309-69-1",100,167.07,0,0,"http://selleckchem.com/products/cefotiam-hydrochloride.html","C18H23N9O4S3.2HCl","dihydrochloride","Cefotiam dihydrochloride, Halospor, Pansporin, Pansporine","Cl.Cl.CN(C)CC[N]1N=NN=C1SCC2=C(N3C(SC2)C(NC(=O)CC4=CSC(=N4)N)C3=O)C(O)=O",-2.796,7,2,10]
["S5006","Teprenone","g4","L1300-21","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Gastroenterology/Inflammation","HSP (HSP90)","Cytoskeletal Signaling","Teprenone, an acylic polyisoprenoid, that is known as tetraprenylacetone or geranylgeranylacetone, is an anti-ulcer drug, clinically used for gastritis.  Teprenone(Geranylgeranylacetone) is an inducer of heat shock proteins (HSPs) expression.",330.55,"6809-52-5",66,199.67,0,0,"http://selleckchem.com/products/teprenone.html","C23H38O",0,"Geranylgeranylacetone, Tetraprenylacetone","CC(C)=CCC/C(C)=C/CC\\C(C)=C\\CC\\C(C)=C\\CCC(C)=O",7.413,1,0,12]
["S5007","Delamanid","h4","L1300-21","in 10mM DMSO","EMA,PMDA",null,null,"Infection","Bacterial","Microbiology","Delamanid (OPC-67683) is a new anti-tuberculosis drug with an excellent intracellular bactericidal activity and a high accumulation rate.",534.48,"681492-22-8",100,187.1,"<1",0,"http://selleckchem.com/products/delamanid.html","C25H25F3N4O6","free base","OPC-67683","CC1(COC2=CC=C(C=C2)N3CCC(CC3)OC4=CC=C(OC(F)(F)F)C=C4)C[N]5C=C(N=C5O1)[N+]([O-])=O",6.452,5,0,9]
["S5009","Brivudine","a5","L1300-21","in 10mM DMSO","HMA","Martindale:The Extra Pharmacopoeia",null,"Infection","CMV","Microbiology","Brivudine (BVDU) is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. It is incorporated into the viral DNA and blocks the action of DNA polymerases, thus inhibiting viral replication.",333.14,"69304-47-8",66,198.11,0,0,"http://selleckchem.com/products/brivudine.html","C11H13BrN2O5","free base","BVDU","OCC1OC(CC1O)N2C=C(\\C=C\\Br)C(=O)NC2=O",-1.034,3,3,3]
["S5010","Indometacin Sodium","b5","L1300-21","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia",null,"Inflammation","COX","Immunology & Inflammation","Indometacin Sodium (Indomethacin Sodium) is the sodium salt of indomethacin, which is a non-selective, reversible, and competitive inhibitor of cyclooxygenases 1 and 2 with anti-inflammatory, analgesic-antipyretic and tocolytic effects.",433.82,"74252-25-8",87,200.55,-1,-2.31,"https://www.selleckchem.com/products/indometacin-sodium.html","C19H21ClNNaO7","sodium salt trihydrate","Indomethacin Sodium","O.O.O.COC1=CC2=C(C=C1)[N](C(=C2CC(=O)O[Na])C)C(=O)C3=CC=C(Cl)C=C3",3.705,4,0,5]
["S5012","Octenidine Dihydrochloride","c5","L1300-21","in 10mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia",null,"Inflammation","Bacterial","Microbiology","Octenidine, a cationic surfactant, is active against gram-positive and gram-negative bacteria.",623.83,"70775-75-6",60,96.18,0,0,"http://selleckchem.com/products/octenidine-ihydrochloride.html","C36H62N4.2HCl","Dihydrochloride","N/A","Cl.Cl.CCCCCCCCN=C1C=CN(CCCCCCCCCCN2C=CC(C=C2)=NCCCCCCCC)C=C1",10.56,2,0,25]
["S5013","Ioversol","d5","L1300-21","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","019710,019710,020923,019710,020923,019710,020923,019710,020923","Diagnosis","Others","Others","Ioversol is an organoiodine compound used as a radiographic contrast agent.",807.11,"87771-40-2",100,123.9,0,0,"http://selleckchem.com/products/lversol.html","C18H24I3N3O9",0,"N/A","OCCN(C(=O)CO)C1=C(I)C(=C(I)C(=C1I)C(=O)NCC(O)CO)C(=O)NCC(O)CO",-2.005,3,8,12]
["S5014","Crisaborole (AN2728)","e5","L1300-21","in 10mM DMSO","FDA,DMF,NDC",null,"207695","Immunology/Inflammation","PDE","Metabolism","Crisaborole (AN2728) is a small-molecule, boron-based, selective PDE4 inhibitor and has broad-spectrum anti-inflammatory activity.",251.05,"906673-24-3",50,199.16,0,0,"http://selleckchem.com/products/crisaborole-an2728.html","C14H10BNO3","free base","N/A","OB1OCC2=CC(=CC=C12)OC3=CC=C(C=C3)C#N",3.538,2,0,2]
["S5015","Simeprevir (TMC435)","f5","L1300-21","in 10mM DMSO","FDA,DMF,EMA,PMDA",null,"205123","Infection","HCV Protease","Proteases","Simeprevir (TMC-435, TMC-435350) is a competitive, reversible, macrocyclic, noncovalent hepatitis C virus (HCV) NS3/4A protease inhibitor that acts directly against the hepatitis C virus. It has a medium inhibitory concentration (IC50) <13 nM for all HCV NS3/4A enzymes(genotypes 1a, 1b, 2, 4, 5, and 6), but has an IC50 value of 37 nM for genotype 3.",749.94,"923604-59-5",100,133.34,"<1",0,"http://selleckchem.com/products/simeprevir.html","C38H47N5O7S2","free base","TMC-435350","COC1=C(C)C2=NC(=CC(=C2C=C1)OC3CC4C(C3)C(=O)N(C)CCCC\\C=C/C5CC5(NC4=O)C(=O)N[S](=O)(=O)C6CC6)C7=NC(=CS7)C(C)C",4.796,9,2,8]
["S5016","Isoprinosine","g5","L1300-21","in 10mM DMSO","DMF",null,null,"Infection","Antiviral,Immunology & Inflammation related","Microbiology","Isoprinosine (Inosine pranobex, Immunovir, Groprinosin, Delimmun) is an immunopharmacologic agent with antiviral activities.",1115.23,"36703-88-5",100,89.67,100,89.67,"http://selleckchem.com/products/isoprinosine.html","C10H12N4O5.3C9H9NO3.3C5H13NO","salt","Inosine pranobex, Immunovir, Groprinosin, Delimmun","CC(O)CN(C)C.CC(O)CN(C)C.CC(O)CN(C)C.CC(=O)NC1=CC=C(C=C1)C(O)=O.CC(=O)NC2=CC=C(C=C2)C(O)=O.CC(=O)NC3=CC=C(C=C3)C(O)=O.OCC4OC(C(O)C4O)[N]5C=NC6=C5N=CNC6=O",-9.137,10,10,14]
["S5017","Oxyclozanide","h5","L1300-21","in 10mM DMSO",null,"BP2019;IP2010;Martindale:The Extra Pharmacopoeia",null,"Parasite","Parasite","Microbiology","Oxyclozanide (Oxiclozanidum, Zanil, Oxyclozanid, Zanilox) is a salicylanilide anthelmintic and mitochondrial uncoupling anthelmintic drug approved for veterinary use.",401.46,"2277-92-1",80,199.27,0,0,"http://selleckchem.com/products/oxyclozanide.html","C13H6Cl5NO3","free base","Oxiclozanidum, Zanil, Oxyclozanid, Zanilox","OC1=C(Cl)C=C(Cl)C=C1NC(=O)C2=C(O)C(=CC(=C2Cl)Cl)Cl",5.452,1,3,2]
["S5019","Indobufen","a6","L1300-21","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease/Hematology","COX","Immunology & Inflammation","Indobufen (Ibustrin, K 3920) is a reversible platelet aggregation inhibitor. Indobufen is a reversible inhibitor of platelet cyclooxygenase (Cox) activity and suppresses thromboxane synthesis.",295.33,"63610-08-2",59,199.78,0,0,"http://selleckchem.com/products/indobufen.html","C18H17NO3","free base","Ibustrin, K 3920","CCC(C(O)=O)C1=CC=C(C=C1)N2CC3=C(C=CC=C3)C2=O",3.157,2,0,4]
["S5020","Tilorone dihydrochloride","b6","L1300-21","in 10mM DMSO","marketed in Russian",null,null,"Infection","Antiviral,IFN","Immunology & Inflammation","Tilorone dihydrochloride is a broad-spectrum, orally active antiviral agent that activates interferon production. It has antitumor, anti-inflammatory properties.",483.47,"27591-69-1",43,88.94,96,198.56,"http://selleckchem.com/products/tilorone-dihydrochloride.html","C25H34N2O3.2HCl","dihydrochloride","N/A","Cl.Cl.CCN(CC)CCOC1=CC2=C(C=C1)C3=C(C=C(OCCN(CC)CC)C=C3)C2=O",5.326,3,0,12]
["S5023","Nadolol","c6","L1300-21","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,JP17,BP2015","074172,074229,074255,074368,074501,201893,203455,207761,208832,209309,210786,210955","Cardiovascular Disease/Neurological Disease","Adrenergic Receptor","Endocrinology & Hormones","Nadolol (Corgard, Solgol, Anabet, SQ11725) is a non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities.",309.4,"42200-33-9",61,197.16,0,0,"http://selleckchem.com/products/nadolol.html","C17H27NO4","free base","Corgard, Solgol, Anabet, SQ11725","CC(C)(C)NCC(O)COC1=CC=CC2=C1CC(O)C(O)C2",1.146,1,4,6]
["S5025","Efinaconazole","d6","L1300-21","in 10mM DMSO","FDA,DMF,NDC,PMDA",null,"203567","Infection","Fungal","Microbiology","Efinaconazole (KP-103) is an inhibitor of 14 alpha-demethylase which is involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes.",348.39,"164650-44-6",69,198.05,"<1",0,"http://selleckchem.com/products/efinaconazole.html","C18H22F2N4O","free base","KP-103","CC(N1CCC(=C)CC1)C(O)(C[N]2C=NC=N2)C3=CC=C(F)C=C3F",2.624,2,0,5]
["S5027","Mebeverine Hydrochloride","e6","L1300-21","in 10mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia,EP9.8,BP2017",null,"Gastroenterology","Others","Others","Mebeverine (Duspatalin, Duspatal, Colofac), a 3-phenylethylamine derivative of methoxybenzamine, acts as a musculotropic antispasmodic agent.",466.01,"2753-45-9",93,199.57,0,0,"http://selleckchem.com/products/mebeverine-hydrochlo.html","C25H35NO5.HCl","hydrochloride","Duspatalin Hydrochloride, Duspatal Hydrochloride, Colofac Hydrochloride","Cl.CCN(CCCCOC(=O)C1=CC=C(OC)C(=C1)OC)C(C)CC2=CC=C(OC)C=C2",5.43,5,0,14]
["S5029","Etofylline","f6","L1300-21","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,EP7.5,BP2010",null,"Cardiovascular Disease","Others","Others","Etofylline (Aethophyllinum, Cordalin, Oxyphylline) is a N-7 substituted theophylline derivative used as a bronchodilator.",224.22,"519-37-9",44,196.24,44,196.24,"http://selleckchem.com/products/etofylline.html","C9H12N4O3",0,"Aethophyllinum, Cordalin, Oxyphylline","CN1C(=O)N(C)C2=C([N](CCO)C=N2)C1=O",-0.64,3,1,2]
["S5030","Dihydralazine sulphate","g6","L1300-21","in 10mM DMSO","CFDA","BP2010",null,"Cardiovascular Disease","Others","Others","Dihydralazine sulphate (Nepresol, Depressan, 1,4-Dihydrazinophthalazine, Hydralazine) is a dihydralazine-l,4-phthalazine derivative and used as an antihypertensive drug.",288.28,"7327-87-9",6,20.81,8,27.75,"http://selleckchem.com/products/dihydralazine-sulphate.html","C8H10N6.H2SO4","sulphate","Nepresol; Depressan; 1,4-Dihydrazinophthalazine sulfate; Hydralazine sulfate","N\\N=C1/NN\\C(=N/N)C2=C1C=CC=C2.O[S](O)(=O)=O",-1.44,2,4,0]
["S5032","Mephenesin","h6","L1300-21","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","NMDAR","Neuronal Signaling","Mephenesin (Decontractyl, Cresoxydiol, Memphenesin, Mephedan) is centrally acting muscle relaxant, a topical analgesic and may be an NMDA receptor antagonist.",182.22,"59-47-2",36,197.56,30,164.64,"http://selleckchem.com/products/mephenesin.html","C10H14O3","free base","Decontractyl, Cresoxydiol, Memphenesin, Mephedan","CC1=C(OCC(O)CO)C=CC=C1",1.249,1,2,4]
["S5033","Terconazole","a7","L1300-21","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2015","021735,075953,076043,076712,076850,077149,077553","Infection","Fungal","Microbiology","Terconazole (Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol,R42470) is a new, broad-spectrum, triazole antifungal agent which is primarily used to treat vaginal fungal infections.",532.46,"67915-31-5",49,92.03,"<1",0,"http://selleckchem.com/products/terconazole.html","C26H31Cl2N5O3","free base","Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol,R42470","CC(C)N1CCN(CC1)C2=CC=C(OCC3COC(C[N]4C=NC=N4)(O3)C5=CC=C(Cl)C=C5Cl)C=C2",4.949,5,0,8]
["S5034","Melitracen hydrochloride","b7","L1300-21","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Melitracen hydrochloride (Thymeol) is a potential dopamine D1/2 receptor antagonist which has antidepressant properties.",327.89,"10563-70-9",65,198.24,65,198.24,"http://selleckchem.com/products/melitracen-hydrochloride.html","C21H25N.HCl","hydrochloride","Thymeol hydrochloride","Cl.CN(C)CC[CH]=[C]1C2=C(C=CC=C2)[C](C)(C)C3=C1C=CC=C3",5.155,0,0,3]
["S5037","Phenazine methosulfate","c7","L1300-21","in 10mM DMSO","FDA",null,"086523","Others","Others","Others","Phenazine methosulfate (N-Methylphenazonium methosulfate, 5-Methylphenazinium methyl sulfate) is widely used as an intermediate electron carrier for coupling the production of NADH or NADPH to the reduction of tetrazolium salts to coloured formazans.",306.34,"299-11-6",61,199.13,0,0,"http://selleckchem.com/products/phenazine-methosulfate.html","C13H11N2.CH3O4S","methosulfate","N-Methylphenazonium methosulfate, 5-Methylphenazinium methyl sulfate","CO[S]([O-])(=O)=O.C[N+]1=C2C=CC=CC2=NC3=CC=CC=C13",0.727,2,0,1]
["S5038","Valethamate Bromide","d7","L1300-21","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Others","Others","Valethamate bromide (Ediposin) is an alkylbenzene which is useful for facilitating cervical ripening, dilatation and thereby decreasing the duration of labor.",386.37,"90-22-2",77,199.29,77,199.29,"http://www.selleckchem.com/products/valethamate-bromide.html","C19H32BrNO2","Bromide","Ediposin","[Br-].CCC(C)C(C(=O)OCC[N+](C)(CC)CC)C1=CC=CC=C1",0.41,2,0,10]
["S5040","Tiamulin","e7","L1300-21","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017",null,"Infection","Ribosomal Peptidyl Transferase","Microbiology","Tiamulin is a semisynthetic pleuromutilin antibiotic that binds to the ribosomal peptidyl transferase centre and inhibits protein synthesis. Tiamulin has sustained antibacterial activity against specified bacterial species and rapidly growing and fastidious animal pathogens.",493.74,"55297-95-5",25,50.63,11,22.28,"http://selleckchem.com/products/tiamulin.html","C28H47NO4S","free base","N/A","CCN(CC)CCSCC(=O)OC1CC(C)(C=C)C(O)C(C)C23CCC(C)C1(C)C2C(=O)CC3",4.361,3,1,10]
["S5041","Difloxacin hydrochloride","f7","L1300-21","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Infection","Antibiotics","Microbiology","Difloxacin is a second-generation, synthetic fluoroquinolone antimicrobial antibiotic used in veterinary medicine.",435.85,"91296-86-5",98,224.85,98,224.85,"http://selleckchem.com/products/difloxacin-hydrochloride.html","C21H19F2N3O3.HCl","hydrochloride","N/A","Cl.CN1CCN(CC1)C2=CC3=C(C=C2F)C(=O)C(=CN3C4=CC=C(F)C=C4)C(O)=O",0.628,2,0,3]
["S5042","Bevantolol hydrochloride","g7","L1300-21","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Bevantolol hydrochloride (NC-1400) is a cardioselective, beta adrenoceptor antagonist, devoid of intrinsic β sympathomimetic activity and with weak membrane-stabilizing and local anesthetic properties.",381.89,"42864-78-8",76,199.01,52,136.16,"http://selleckchem.com/products/bevantolol-hydrochloride.html","C20H27NO4.HCl","hydrochloride","NC-1400 hydrochloride","Cl.COC1=C(OC)C=C(CCNCC(O)COC2=CC=CC(=C2)C)C=C1",3.645,3,2,10]
["S5043","Benorylate","h7","L1300-21","in 10mM DMSO","CFDA",null,null,"Inflammation/Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Benorylate (Benorilate, Benoral, Benortan) is the esterification product of paracetamol and acetylsalicylic acid with anti-inflammatory, analgesic and antipyretic properties.",313.3,"5003-48-5",62,197.89,0,0,"http://selleckchem.com/products/benorylate.html","C17H15NO5","free base","Benorilate, Benoral, Benortan","CC(=O)NC1=CC=C(OC(=O)C2=C(OC(C)=O)C=CC=C2)C=C1",2.15,5,1,6]
["S5046","Clonixin","a8","L1300-21","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Hematology/Inflammation/Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Clonixin (Clonixic acid) is a nonsteroidal anti-inflammatory drug with analgesic, antipyretic, and platelet-inhibitory actions.",262.69,"17737-65-4",52,197.95,"<1",0,"http://selleckchem.com/products/clonixin.html","C13H11ClN2O2","free base","Clonixic acid","CC1=C(NC2=C(C=CC=N2)C(O)=O)C=CC=C1Cl",3.549,2,1,3]
["S5049","Thiocolchicoside","b8","L1300-21","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,EP9.3,BP2017,IP2010",null,"Neurological Disease/Inflammation","GABA Receptor","Neuronal Signaling","Thiocolchicoside (Thiocolchicine 2-glucoside analog, Coltramyl) is a natural occuring glycoside originated from the flower seeds of superba gloriosa with anti-inflammatory and analgesic properties as well as pronounced convulsant activity. It is also an antagonist of GABAA receptor.",563.62,"602-41-5",100,177.42,100,177.42,"http://selleckchem.com/products/thiocolchicoside.html","C27H33NO10S",0,"Thiocolchicine 2-glucoside analog, Coltramyl","COC1=C(OC)C2=C(CCC(NC(C)=O)C3=CC(=O)C(=CC=C23)SC)C=C1OC4OC(CO)C(O)C(O)C4O",0.446,6,5,7]
["S5052","Granisetron","c8","L1300-21","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,BP2017","077177,077186,077187,077297,077842,077913,077963,078037,078080,078090,078197,078198,078221,078258,078260,078262,078392,078522,078531,078534,078564,078565,078566,078629,078678,078725,078808,078835,078843,078846,078863,078880,078969,079078,079119,090817,091136,091137,091274,203453,203454,204238","Gastroenterology","5-HT Receptor","Neuronal Signaling","Granisetron (Sancuso, Kevatril, Granisetronum, Sustol) is a serotonin receptor (5HT-3 selective) antagonist that is used as an antiemetic and antinauseant for cancer chemotherapy.",312.41,"109889-09-0",11,35.21,0,0,"http://selleckchem.com/products/granisetron.html","C18H24N4O",0,"Sancuso, Kevatril, Granisetronum, Sustol","CN1C2CCCC1CC(C2)NC(=O)C3=N[N](C)C4=C3C=CC=C4",2.401,2,1,2]
["S5053","Imazalil","d8","L1300-21","in 10mM DMSO",null,"EP10.4",null,"Others","Others","Microbiology","Imazalil (Enilconazole, Chloramizole) is a fungicide widely used in agriculture, also used in veterinary medicine as a topical antimycotic.",297.18,"35554-44-0",59,198.53,0,0,"http://selleckchem.com/products/imazalil.html","C14H14Cl2N2O","free base","Enilconazole, Chloramizole","ClC1=CC=C(C(C[N]2C=CN=C2)OCC=C)C(=C1)Cl",3.349,2,0,6]
["S5054","Rifamycin sodium salt","e8","L1300-21","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.6,KP Ⅹ,BP2017",null,"Infection","Antineoplastic and Immunosuppressive Antibiotics,Bacterial","Microbiology","Rifamycin sodium is an antibacterial drug used for treatment of mycobacterium infections.",719.75,"14897-39-3",100,138.94,-1,-1.39,"https://www.selleckchem.com/products/rifamycin-sodium-salt.html","C37H46NNaO12",0,0,"[Na+].COC1/C=C/OC2(C)OC3=C(C2=O)C4=C(C(=C3C)O)C(=C(NC(=O)\\C(=C/C=C/C(C)C(O)C(C)C(O)C(C)C(C1C)C(=O)OC)C)C=C4[O-])O",3.125,7,5,3]
["S5055","Milbemycin Oxime","f8","L1300-21","in 10mM DMSO",null,"USP42-NF37;EP9.2;BP2019",null,"Infection/Parasitology","Parasite","Microbiology","Milbemycin Oxime is a broad spectrum anti-parasitic drug that is active against worms (anthelmintic) and mites (miticide).",0,"129496-10-2",100,10,"<1",0,"http://selleckchem.com/products/milbemycin-oxime.html","C30H40NO7R2",0,"N/A","CC1C(OC2(CC1)CC3CC(C/C=C(C)/CC(C)\\C=C\\C=C\\4COC5/C(=N/O)C(=CC(C(=O)O3)C45O)C)O2)[R]",4.783,6,0,0]
["S5056","Dinoprost tromethamine","g8","L1300-21","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","017434","Diagnosis","Prostaglandin Receptor","GPCR & G Protein","Dinoprost Tromethamine (Dinolytic, PGF2-alpha tham, Zinoprost, Prostin F2 alpha, Dinoprost Trometamol) is a synthetic analogue of the naturally occurring prostaglandin F2 alpha, which stimulates myometrial activity, relaxes the cervix, inhibits corpus luteal steroidogenesis, and induces luteolysis by direct action on the corpus luteum.",475.62,"38562-01-5",95,199.74,95,199.74,"https://www.selleckchem.com/products/dinoprost-tromethamine.html","C20H34O5.C4H11NO3","tromethamine","Dinolytic, PGF2-alpha tham, Zinoprost, Prostin F2 alpha, Dinoprost Trometamol","CCCCCC(O)/C=C/C1C(O)CC(O)C1C\\C=C/CCCC(O)=O.NC(CO)(CO)CO",-1.877,1,7,15]
["S5058","Revaprazan Hydrochloride","h8","L1300-21","in 10mM DMSO","marketed in Korea","Martindale:The Extra Pharmacopoeia",null,"Gastroenterology/Inflammation","ATPase,Proton Pump","Transmembrane Transporters","Revaprazan Hydrochloride (YH1885) is a new reversible proton pump inhibitor with long-lasting acid-suppressive effects. Revaprazan Hydrochloride reversibly inhibits H(+)/K(+)-ATPase via binding to the K+-binding site of the pump.",398.9,"178307-42-1",16,40.11,0,0,"http://selleckchem.com/products/revaprazan-hydrochloride.html","C22H23FN4.HCl","HCl","YH1885","Cl.CC1N(CCC2=C1C=CC=C2)C3=NC(=NC(=C3C)C)NC4=CC=C(F)C=C4",6.215,2,1,3]
["S5059","Pixantrone Maleate","a9","L1300-21","in 10mM DMSO","EMA","Martindale:The Extra Pharmacopoeia",null,"Cancer","Topoisomerase","DNA Damage/DNA Repair","Pixantrone (BBR-2778) is a novel aza-anthracenedione compound with antitumor activity. It is a weak topoisomerase II inhibitor and forms stable DNA adducts through alkylation with specificity for DNA hypermethylated sites.",557.51,"144675-97-8",100,179.37,100,179.37,"http://selleckchem.com/products/pixantrone-maleate.html","C17H19N5O2.2C4H4O4","dimaleate","BBR-2778","NCCNC1=CC=C(NCCN)C2=C1C(=O)C3=C(C=NC=C3)C2=O.OC(=O)\\C=C/C(O)=O.OC(=O)\\C=C/C(O)=O",-5.263,7,4,10]
["S5060","Metadoxine","b9","L1300-21","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Psychotic disorders","5-HT Receptor","Neuronal Signaling","Metadoxine (Metadoxil, Metasin, pyridoxine-pyrrolidone carboxylat), also known as pyridoxine-pyrrolidone carboxylate, is a drug used to treat chronic and acute alcohol intoxication.  Metadoxine is a novel 5-HT2B receptor antagonist with a possible therapeutic role in treating ADHD.",298.29,"74536-44-0",59,197.79,0,0,"http://selleckchem.com/products/metadoxine.html","C8H11NO3.C5H7NO3","salt","Metadoxil, Metasin, pyridoxine-pyrrolidone carboxylat","CC1=C(O)C(=C(CO)C=N1)CO.OC(=O)C2CCC(=O)N2",-1.243,3,4,3]
["S5062","Daclatasvir Dihydrochloride","c9","L1300-21","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"206843","Infection","HCV Protease","Microbiology","Daclatasvir is an orally available antiviral agent that inhibits the NS5A region of the hepatitis C virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection.",811.8,"1009119-65-6",100,123.18,100,123.18,"https://www.selleckchem.com/products/daclatasvir-dihydrochloride.html","C40H50N8O6.2HCl","dihydrochloride","N/A","Cl.Cl.COC(=O)NC(C(C)C)C(=O)N1CCCC1C2=NC=C([NH]2)C3=CC=C(C=C3)C4=CC=C(C=C4)C5=CN=C([NH]5)C6CCCN6C(=O)C(NC(=O)OC)C(C)C",5.812,8,4,13]
["S5063","Trelagliptin succinate","d9","L1300-21","in 10mM DMSO","PMDA",null,null,"Endocrinology/Metabolic Disease","DPP","Proteases","Trelagliptin succinate (SYR472) is a dipeptidyl peptidase IV (DPP-4) inhibitor which is used as a new long-acting drug for once-weekly treatment of type 2 diabetes mellitus (DM).",475.47,"1029877-94-8",95,199.8,95,199.8,"http://selleckchem.com/products/trelagliptin-succinate.html","C18H20FN5O2.C4H6O4","succinate","SYR472","CN1C(=O)C=C(N2CCCC(N)C2)N(CC3=CC(=CC=C3C#N)F)C1=O.OC(=O)CCC(O)=O",-1.362,4,1,6]
["S5065","Ganciclovir sodium","e9","L1300-21","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","076222,207645","Infection","CMV","Microbiology","Ganciclovir Sodium (RS-21592, Cytovene IV, BW 759, 2'-Nor-2'-deoxyguanosine) is the sodium salt form of ganciclovir, a synthetic, antiviral, purine nucleoside analog with antiviral activity, especially against cytomegalovirus (CMV).",277.21,"107910-75-8",55,198.41,55,198.41,"https://www.selleckchem.com/products/ganciclovir-sodium.html","C9H12N5NaO4",0,"RS-21592 sodium, Cytovene IV sodium, BW 759 sodium, 2'-Nor-2'-deoxyguanosine sodium","[Na+].NC1=NC2=C(N=C[N]2COC(CO)CO)C(=N1)[O-]",-1.859,4,3,5]
["S5066","Pramipexole dihydrochloride","f9","L1300-21","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37,EP9.1,BP2017","077724,077854,078551,078894,078920,090151,090190,090241,090764,090781,090865,091254,091450,091683,201963,202164,202206,202353,202633,202702,202891,203354,203615,203855,204518,206156,207011,211088","Neurological Disease","Dopamine Receptor","Neuronal Signaling","Pramipexole dihydrochloride (SND919) is a dopamine agonist of the non-ergoline class indicated for treating Parkinson's disease (PD) and restless legs syndrome (RLS) with Ki values of 3.9 nM, 2.2 nM, 0.5 nM and 5.1 nM for D2S receptor, D2L receptor, D3 receptor and D4 receptor.",284.25,"104632-25-9",56,197.01,0,0,"http://selleckchem.com/products/pramipexole-dihydrochloride.html","C10H17N3S.2HCl","dihydrochloride","SND919","Cl.Cl.CCCNC1CCC2=C(C1)SC(=N2)N",2.147,1,2,3]
["S5067","Losartan","g9","L1300-21","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017","076958,077424,077459,078232,078243,090083,090382,090428,090467,090544,090790,091129,091497,091541,091590,200290,201170,202230,203030,203835,204795","Cardiovascular Disease/Endocrinology/Metabolic Disease","Angiotensin Receptor","GPCR & G Protein","Losartan(DuP-753) is a selective, orally administered, nonpeptide blocker of angiotensin II type 1 (AT1) receptor used to treat high blood pressure, diabetic kidney disease, heart failure, and left ventricular enlargement.",422.91,"114798-26-4",84,198.62,-1,-2.36,"https://www.selleckchem.com/products/losartan.html","C22H23ClN6O","free base","DuP-753","CCCCC1=NC(=C(CO)[N]1CC2=CC=C(C=C2)C3=C(C=CC=C3)C4=NN=N[NH]4)Cl",4.241,4,2,8]
["S5069","Dabrafenib Mesylate","h9","L1300-21","in 10mM DMSO","FDA,DMF",null,"202806","Cancer","Raf","MAPK","Dabrafenib Mesylate (GSK2118436) is the mesylate salt form of dabrafenib, an orally bioavailable inhibitor of B-raf (BRAF) protein with IC50s of 0.8 nM, 3.2 nM and 5 nM for B-Raf (V600E), B-Raf (WT) and C-Raf, respectively.",615.67,"1195768-06-9",100,162.42,"<1",0,"http://selleckchem.com/products/dabrafenib-mesylate.html","C23H20F3N5O2S2.CH4O3S","mesylate","GSK2118436 Mesylate","CC(C)(C)C1=NC(=C(S1)C2=CC=NC(=N2)N)C3=C(F)C(=CC=C3)N[S](=O)(=O)C4=C(F)C=CC=C4F.C[S](O)(=O)=O",4.963,5,2,6]
["S5070","Mupirocin calcium","a10","L1300-21","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.7,KP Ⅹ,JP17,BP2017","050703,050746,201587","Infection","Antibiotics,Bacterial","Microbiology","Mupirocin Calcium (Pseudomonic acid A) is the calcium salt form of mupirocin, a natural crotonic acid derivative extracted from Pseudomonas fluorescens,which inhibits bacterial protein synthesis and is used as an antibiotic.",1075.34,"115074-43-6",100,92.99,6,5.58,"http://selleckchem.com/products/mupirocin-calcium.html","C52H86CaO18.2H2O","calcium salt dihydrate","Pseudomonic acid A","O.O.CC(O)C(C)C1OC1CC2COC(C\\C(C)=C\\C(=O)OCCCCCCCCC(=O)O[Ca]OC(=O)CCCCCCCCOC(=O)\\C=C(C)\\CC3OCC(CC4OC4C(C)C(C)O)C(O)C3O)C(O)C2O",5.246,12,6,38]
["S5071","Duloxetine","b10","L1300-21","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","090669,090694,090723,090728,090739,090745,090773,090774,090775,090776,090778,090780,090783,202045,202336,202949,203088,203197,204343,204815,206653,208706,210599,211310","Neurological Disease/Psychotic disorders","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Duloxetine (LY-248686) is a potent inhibitor of serotonin (5-hydroxytryptamine, 5-HT) and noradrenaline (NE) uptake in vitro and in vivo and is 3- to 5-times more effective at inhibiting 5-HT uptake.",297.41,"116539-59-4","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/duloxetine.html","C18H19NOS","free base","LY-248686","CNCCC(OC1=CC=CC2=CC=CC=C12)C3=CC=CS3",3.846,1,1,6]
["S5073","Donepezil","c10","L1300-21","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,JP17,IP2010","076786,076893,077344,077518,077975,078388,078662,078841,090056,090100,090175,090247,090290,090425,090493,090521,090551,090686,090768,091198,091267,200292,201001,201146,201335,201634,201724,201787,202114,202410,202415,202542,202631,202656,202723,202782,203034,203104,203114,203162,203419,203656,203713,203907,204293,204609,204831,205269","Neurological Disease","AChR","Neuronal Signaling","Donepezil (Aricept, Donepezilo) is a piperidine based, potent, specific, non-competitive and reversible inhibitor of acetylcholinesterase (AChE) used for the treatment of mild to moderate dementia of the Alzheimer's type.",379.49,"120014-06-4",75,197.63,0,0,"http://selleckchem.com/products/donepezil.html","C24H29NO3","free base","Aricept, Donepezilo","COC1=CC2=C(C=C1OC)C(=O)C(CC3CCN(CC3)CC4=CC=CC=C4)C2",4.569,3,0,6]
["S5074","Argatroban Monohydrate","d10","L1300-21","in 10mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia",null,"Hematology","Thrombin","Proteases","Argatroban (Argatroban hydrate, Argipidine,MCI-9038 Monohydrate) is a direct, selective thrombin inhibitor with anticoagulant effects.",526.65,"141396-28-3",100,189.88,"<1",0,"http://selleckchem.com/products/argatroban-monohydrate.html","C23H36N6O5S.H2O",0,"Argatroban hydrate, Argipidine,MCI-9038 Monohydrate","O.CC1CCN(C(C1)C(O)=O)C(=O)C(CCCNC(N)=N)N[S](=O)(=O)C2=CC=CC3=C2NCC(C)C3",1.059,4,4,10]
["S5075","Acotiamide","e10","L1300-21","in 10mM DMSO","DMF,PMDA",null,null,"Gastrointestinal Disease","AChR","Neuronal Signaling","Acotiamide (Acofide, Z388) is a novel acetylcholinesterase inhibitor with fundus-relaxing and gastroprokinetic properties.",450.55,"185106-16-5",90,199.76,"<1",0,"http://selleckchem.com/products/acotiamide.html","C21H30N4O5S","free base","Acofide, Z388","COC1=C(OC)C=C(C(=O)NC2=NC(=CS2)C(=O)NCCN(C(C)C)C(C)C)C(=C1)O",2.565,5,3,10]
["S5076","Xipamide","f10","L1300-21","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease/Metabolic Disease","Others","Others","Xipamide is a sulfonamide-based diuretic as well as a saluretic with antihypertensive activity.",354.81,"14293-44-8",70,197.29,"<1",0,"http://selleckchem.com/products/xipamide.html","C15H15ClN2O4S","free base","N/A","CC1=C(NC(=O)C2=CC(=C(Cl)C=C2O)[S](N)(=O)=O)C(=CC=C1)C",2.714,3,3,3]
["S5077","Regorafenib (BAY-734506) Monohydrate","g10","L1300-21","in 10mM DMSO","FDA,DMF,EMA,NDC","EP9.8","203085,204369","Angiology/Cancer","c-Kit,c-RET,PDGFR,Raf,VEGFR","Protein Tyrosine Kinase","Regorafenib (BAY-734506, Fluoro-sorafenib, Resihance, Stivarga, regorafaenib monohydrate) Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, Kit (c-Kit), RET (c-RET), RAF-1, B-RAF and B-RAF(V600E) respectively.",500.83,"1019206-88-2",100,199.67,0,0,"http://selleckchem.com/products/regorafenib-monohydrate.html","C21H15ClF4N4O3.H2O","monohydrate","Fluoro-sorafenib, Resihance, Stivarga, regorafaenib monohydrate","O.CNC(=O)C1=NC=CC(=C1)OC2=CC=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C(=C2)F",4.174,4,3,6]
["S5078","Osimertinib mesylate","h10","L1300-21","in 10mM DMSO","DMF,EMA,NDC,FDA,marketed in Japan",null,"208065","Cancer/Respiratory Disease","EGFR","Protein Tyrosine Kinase","Osimertinib mesylate (AZD9291) is the mesylate form of osimertinib, which is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug.",595.71,"1421373-66-1",9,15.11,-1,0,"http://www.selleckchem.com/products/osimertinib-mesylate.html","C29H37N7O5S","mesylate","AZD9291 mesylate","COC1=C(NC2=NC=CC(=N2)C3=C[N](C)C4=C3C=CC=C4)C=C(NC(=O)C=C)C(=C1)N(C)CCN(C)C.C[S](O)(=O)=O",4.257,4,2,10]
["S5079","Sitagliptin","a11","L1300-21","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","202327,202387,202423,202425,202473,202487,208186","Endocrinology/Metabolic Disease","DPP","Proteases","Sitagliptin (MK-0431) is an oral and highly selective DPP-4 inhibitor with an IC50 of 18 nM. It is used for the treatment of type 2 diabetes.",407.31,"486460-32-6",81,198.87,0,0,"http://selleckchem.com/products/sitagliptin.html","C16H15F6N5O","free base","MK-0431","NC(CC(=O)N1CC[N]2C(=NN=C2C(F)(F)F)C1)CC3=C(F)C=C(F)C(=C3)F",1.93,3,1,5]
["S5081","Ceforanide","b11","L1300-21","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","050554,062579","Infection","Bacterial","Microbiology","Ceforanide is a new cephalosporin with antibacterial activity and has a longer elimination half-life than any currently available cephalosporin.",519.55,"60925-61-3",6,11.55,0,0,"http://selleckchem.com/products/ceforanide.html","C20H21N7O6S2","free base","N/A","NCC1=CC=CC=C1CC(=O)NC2C3SCC(=C(N3C2=O)C(O)=O)CSC4=NN=N[N]4CC(O)=O",-3.235,7,2,10]
["S5082","Vitamin K2","c11","L1300-21","in 10mM DMSO","CFDA",null,null,"Others","Vitamin","Metabolism","Vitamin K2 (Menaquinone) is an important fat-soluble vitamin that plays critical roles in protecting heart and brain, and building strong bones. It also plays an important role in cancer protection.",444.65,"863-61-6",88,197.91,0,0,"http://selleckchem.com/products/vitamin-k2.html","C31H40O2","free base","Menaquinone","CC(C)=CCC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC1=C(C)C(=O)C2=C(C=CC=C2)C1=O",9.5,2,0,11]
["S5083","Lentinan","d11","L1300-21","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia",null,"Cancer/Inflammation","Fungal,Immunology & Inflammation related","Immunology & Inflammation","Lentinan (A823605, Bromoduline), isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.",0,"37339-90-5",100,10,0,0,"http://selleckchem.com/products/lentinan.html","C42H70O35R2",0,"A823605, Bromoduline","O(C1C(O)C(CO)OC(OCC2OC(OC3C(O)C(CO)OC(OC4C(O)C(COC5OC(CO)C(O)C(O)C5O)OC(OC6C(O)C(OC(CO)C6O)[*])C4O)C3O)C(O)C(OC7OC(CO)C(O)C(O)C7O)C2O)C1O)[*]",-10.494,14,21,20]
["S5084","Carbazochrome","e11","L1300-21","in 10mM DMSO","CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Hematology","Others","Others","Carbazochrome (Adedolon, Adchnon, Adrenostazin, Cromadrenal, Adona, AC-17) is a hemostatic agent that causes the aggregation and adhesion of platelets in the blood to form a platelet plug, ceasing blood flow from an open wound.",236.23,"69-81-8",33,139.69,0,0,"http://selleckchem.com/products/carbazochrome.html","C10H12N4O3","free base","Adedolon, Adchnon, Adrenostazin, Cromadrenal, Adona, AC-17","CN1CC(O)C2=C\\C(=N\\NC(N)=O)C(=O)C=C12",-1.119,3,3,1]
["S5085","Azamethiphos","f11","L1300-21","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","Others","Others","Azamethiphos is an organophosphate (OP) pesticide used to combat sea lice infestations in farmed salmonids.",324.68,"35575-96-3",64,197.12,0,0,"http://selleckchem.com/products/azamethiphos.html","C9H10ClN2O5PS","free base","N/A","CO[P](=O)(OC)SCN1C(=O)OC2=C1N=CC(=C2)Cl",1.793,5,0,5]
["S5086","p-Anisaldehyde","g11","L1300-21","in 10mM DMSO",null,"USP42-NF37",null,"Others","Fungal","Microbiology","p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde), an extract from Pimpinella anisum seeds, exhibits antifungal activity against a number of yeast and mold strains in laboratory media, fruit purees and fruit juices.",136.15,"123-11-5","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/p-anisaldehyde.html","C8H8O2","free base","4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde","COC1=CC=C(C=O)C=C1",1.573,2,0,2]
["S5091","Geranyl acetate","h11","L1300-21","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Others","Apoptosis","Geranyl acetate (Geraniol acetate, Geranyl ethanoate) is a natural organic compound that is used primarily as a component of perfumes for creams and soaps and as a flavoring ingredient. Geranyl acetate exhibits anti-cancer effects by inducing cell apoptosis.",196.29,"105-87-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/geranyl-acetate.html","C12H20O2","free base","Geraniol acetate, Geranyl ethanoate","CC(=O)OC/C=C(C)/CCC=C(C)C",3.313,2,0,6]
["S5092","Febantel","a2","L1300-22","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia;CP2005",null,"Parasite","Parasite","Microbiology","Febantel (Rintal, Combotel, Oratel, Bay Vh 5757, Negabot Plus) is a prodrug that is metabolized to fenbendazole and oxfendazole, which are undoubtedly the active parasiticides.",446.48,"58306-30-2",89,199.34,0,0,"http://selleckchem.com/products/febantel.html","C20H22N4O6S","free base","Rintal, Combotel, Oratel, Bay Vh 5757, Negabot Plus","COCC(=O)NC1=C(C=CC(=C1)SC2=CC=CC=C2)N=C(NC(=O)OC)NC(=O)OC",3.036,7,3,10]
["S5093","Rafoxanide","b2","L1300-22","in 10mM DMSO",null,"IP2010",null,"Parasite","Parasite","Microbiology","Rafoxanide (Disalan, Ranide, Flukanide, Bovanide) is a salicylanilide used as an anthelmintic, being effective treatment for the control of fluke infections in animals.",626.01,"22662-39-1",100,159.74,0,0,"http://selleckchem.com/products/rafoxanide.html","C19H11Cl2I2NO3","free base","Disalan, Ranide, Flukanide, Bovanide","OC1=C(I)C=C(I)C=C1C(=O)NC2=CC(=C(OC3=CC=C(Cl)C=C3)C=C2)Cl",6.418,2,2,4]
["S5096","SulfadiMethoxine sodium","c2","L1300-22","in 10mM DMSO","DMF","BP2017,USP39-NF34",null,"Infection","Anti-infection","Microbiology","Sulfadimethoxine (Sulfadimethoxydiazine) is a long-lasting sulfonamide antimicrobial agent used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections.",332.31,"1037-50-9",66,198.61,0,0,"http://selleckchem.com/products/sulfadiMethoxine-sodium.html","C12H13N4O4S.Na","sodium salt","Sulfadimethoxydiazine sodium","COC1=NC(=NC(=C1)N([Na])[S](=O)(=O)C2=CC=C(N)C=C2)OC",1.462,6,1,5]
["S5100","Pralidoxime Iodide","d2","L1300-22","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","AChR","Neuronal Signaling","Pralidoxime Iodide (2-PAM) is an antidote approved for reactivation of inhibited acetylcholinesterase (AChE) in organophosphate poisoning.",264.06,"94-63-3",52,196.92,0,0,"http://selleckchem.com/products/pralidoxime-lodide.html","C7H9N2O.I","iodide salt","2-PAM","[I-].C[N+]1=C(C=CC=C1)\\C=N\\O",-1.56,1,0,1]
["S5102","stachyose tetrahydrate","e2","L1300-22","in 10mM DMSO",null,"USP42-NF37",null,"Others","Others","Others","stachyose tetrahydrate is a natural sugar found in many foods like beans and vegetables.",738.64,"10094-58-3",100,135.38,100,135.38,"https://www.selleckchem.com/products/stachyose.html","C24H42O21.4H2O","free base","N/A","O.O.O.O.OCC1OC(OCC2OC(OCC3OC(OC4(CO)OC(CO)C(O)C4O)C(O)C(O)C3O)C(O)C(O)C2O)C(O)C(O)C1O",-8.634,7,14,11]
["S5105","Proanthocyanidins","f2","L1300-22","in 10mM DMSO",null,"USP42-NF37",null,"Angiology/Infection/Ophthalmology","Bacterial","Microbiology","Proanthocyanidins (PAs), also known as condensed tannins, are a class of polyphenols found in a variety of plants. They are very powerful antioxidants that remove harmful free oxygen radicals from cells.",594.52,"20347-71-1",100,168.2,"<1",0,"http://selleckchem.com/products/proanthocyanidins.html","C30H26O13","free base","condensed tannins","OC1C(O)C(OC2CC3=C(OC2C4=CC=C(O)C(=C4)O)C=C(O)C=C3O)(OC5=C1C(=CC(=C5)O)O)C6=CC=C(O)C(=C6)O",0,0,0,0]
["S5106","Lanolin","g2","L1300-22","in 10mM DMSO","DMF,NDC,PMDA,HMA","USP42-NF37,KP Ⅹ,JP16",null,"Inflammation","Others","Others","Lanolin (wool wax, wool grease) is a wax secreted by the sebaceous glands of wool-bearing animals and used widely in the pharmaceutical and cosmetics industries.",0,"8006-54-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/lanolin.html",0,0,"wool wax, wool grease",0,0,0,0,0]
["S5108","Tylosin","h2","L1300-22","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,JP17,BP2017,IP2010",null,"Infection","Antibiotics","Microbiology","Tylosin (Fradizine, Tylocine, Tylosine, Tylosin A) is a macrolide-class broad spectrum antibiotic that's used in veterinary medicine to treat felines, canines and livestock.",916.1,"1401-69-0",100,109.16,0,0,"http://selleckchem.com/products/tylosin.html","C46H77NO17","free base","Fradizine, Tylocine, Tylosine, Tylosin A","CCC1OC(=O)CC(O)C(C)C(OC2OC(C)C(OC3CC(C)(O)C(O)C(C)O3)C(C2O)N(C)C)C(CC=O)CC(C)C(=O)/C=C/C(=C/C1COC4OC(C)C(O)C(OC)C4OC)C",0,0,0,0]
["S5109","Ademetionine","a3","L1300-22","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,USP36-NF31",null,"Inflammation/Psychotic disorders","Others","Others","Ademetionine (AdoMet, S-Adenosylmethionine, SAMe), also known as SAMe, is a specific form of the amino acid methionine known as S-adenosyl-methionine. It is essential for the formation of glutathione, a water-soluble peptide that helps the body fight free radicals.",398.44,"29908-03-0",79,198.27,0,0,"http://selleckchem.com/products/ademetionine.html","C15H22N6O5S","free base","AdoMet, S-Adenosylmethionine, SAMe","C[S+](CCC(N)C([O-])=O)CC1OC(C(O)C1O)[N]2C=NC3=C2N=CN=C3N",0,0,0,0]
["S5112","alpha-Arbutin","b3","L1300-22","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Alpha-arbutin (alpha-Arbutoside, 4-hydroxyphenyl-D-lucopyranoside) is a synthetic and functional active ingredient for skin lightening.",272.25,"84380-01-8",54,198.35,0,0,"http://selleckchem.com/products/alpha-arbutin.html","C12H16O7","free base","alpha-Arbutoside, 4-hydroxyphenyl-D-lucopyranoside","OCC1OC(OC2=CC=C(O)C=C2)C(O)C(O)C1O",0,0,0,0]
["S5113","Propyl gallate","c3","L1300-22","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010",null,"Others","PPAR","Metabolism","Propyl gallate (Gallic acid propyl esterZ, n-Propyl gallate) is an antioxidant used in foods especially animal fats and vegetable oils, also in a wide variety of cosmetics and beauty care products.",212.2,"121-79-9",42,197.93,0,0,"http://selleckchem.com/products/propyl-gallate.html","C10H12O5","free base","Gallic acid propyl esterZ, n-Propyl gallate","CCCOC(=O)C1=CC(=C(O)C(=C1)O)O",0,0,0,0]
["S5114","Hydroquinine","d3","L1300-22","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Hydroquinine (Dihydroquinine), also known as dihydroquinine, is an organic compound and as a cinchona alkaloid closely related to quinine.",326.43,"522-66-7",65,199.12,0,0,"http://selleckchem.com/products/hydroquinine.html","C20H26N2O2","free base","Dihydroquinine","CCC1CN2CCC1CC2C(O)C3=CC=NC4=C3C=C(OC)C=C4",0,0,0,0]
["S5117","Doramectin","e3","L1300-22","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","Others","Others","Doramectin (Cyclohexylavermectin B1, Dectomax) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. It is used for the treatment and control of internal parasitosis, ticks and mange.",899.11,"117704-25-3",100,111.22,0,0,"http://selleckchem.com/products/doramectin.html","C50H74O14","free base","Cyclohexylavermectin B1, Dectomax","COC1CC(OC(C)C1O)OC2C(C)OC(CC2OC)OC\\3C(C)/C=C/C=C/4COC5C(O)C(=CC(C(=O)OC6CC(C/C=C3C)OC7(C6)OC(C(C)C=C7)C8CCCCC8)C45O)C",0,0,0,0]
["S5121","Phytol","f3","L1300-22","in 10mM DMSO","NDC",null,null,"Infection/Parasitology","PPAR","Metabolism","Phytol (Trans-Phytol), a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, shows antinociceptive and antioxidant activities as well as anti-inflammatory and antiallergic effects. It is a specific activator of PPARα.",296.53,"150-86-7","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/phytol.html","C20H40O","free base","Trans-Phytol","CC(C)CCCC(C)CCCC(C)CCC\\C(C)=C\\CO",0,0,0,0]
["S5126","Aleuritic Acid","g3","L1300-22","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Others","Others","Aleuritic Acid (Aleuritolic acid, 9,10,16-trihydroxy-palmitic acid), a major constituent acid of lac resin (shellac), is isolated from the resin and mainly used in the perfumery industry as a starting material for the preparation of \"musk\" aroma compounds as well as medicinal and bioactive compounds.",304.42,"533-87-9",60,197.1,0,0,"http://selleckchem.com/products/aleuritic-acid.html","C16H32O5","free base","Aleuritolic acid, 9,10,16-trihydroxy-palmitic acid","OCCCCCCC(O)C(O)CCCCCCCC(O)=O",0,0,0,0]
["S5130","Taurocholic acid sodium salt hydrate","h3","L1300-22","in 10mM DMSO","DMF","USP43-NF38",null,"Others","Others","Others","Taurocholic acid (Sodium taurocholate hydrate), a bile salt formed in the liver, is the product of conjugation of cholic acid with taurine that is involved in the emulsification of lipids. Its sodium salt is the chief ingredient of the bile of carnivorous animals.","537.68 (anhydrous basis)","345909-26-4",100,185.98,0,0,"http://selleckchem.com/products/taurocholic-acid-sodium-salt-hydrate.html","C26H45NO7S.xH2O.Na","sodium salt, hydrate","Sodium taurocholate hydrate","[Na+].CC(CCC(=O)NCC[S]([O-])(=O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CC(O)C12C",0,0,0,0]
["S5132","Casanthranol","a4","L1300-22","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37",null,"Gastroenterology","Others","Others","Casanthranol is a purified mixture of te antranol glycosides derived from Cascara sagrada.","N/A","8024-48-4",100,0,0,0,"http://selleckchem.com/products/casanthranol.html","C26H44NNaO7RS",0,"N/A",0,0,0,0,0]
["S5134","D(-)-Arabinose","b4","L1300-22","in 10mM DMSO",null,"EP9.2;BP2018",null,"Metabolic Disease","Others","Others","D-Arabinose is a reducing sugar useful as a substrate in analysis of arabinose isomerases and synthesis of D-erythroascorbic acid in yeast.",150.13,"28697-53-2",30,199.83,0,0,"http://selleckchem.com/products/d-arabinose.html","C5H10O5","free base","D-arabinose","OC1COC(O)C(O)C1O",0,0,0,0]
["S5138","Citral","c4","L1300-22","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Others","Immunology & Inflammation related","Immunology & Inflammation","Citral (Geranialdehyde) is an α,β-unsaturated aldehyde present in the oils of several plants. It is an aroma compound used in perfumery for its citrus effect and is also used as a flavor and for fortifying lemon oil.",152.23,"5392-40-5","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/citral.html","C10H16O","free base","Geranialdehyde","CC(C)=CCCC(/C)=C/C=O",0,0,0,0]
["S5141","Pyrithioxin","d4","L1300-22","in 10mM DMSO","CFDA",null,null,"Immunology/Inflammation/Neurological Disease","Others","Others","Pyrithioxin (Bonifen, Encefabol, Pyritinol, Vitamin B6 disulfide) is a neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity.",368.47,"1098-97-1",60,162.84,0,0,"http://selleckchem.com/products/pyrithioxin.html","C16H20N2O4S2","free base","Bonifen, Encefabol, Pyritinol, Vitamin B6 disulfide","CC1=NC=C(CSSCC2=CN=C(C)C(=C2CO)O)C(=C1O)CO",0,0,0,0]
["S5143","Citropten","e4","L1300-22","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Others","Others","Citropten (5,7-Dimethoxycoumarin, Citroptene, Limettin, Limetin) is a natural organic compound  which belongs to coumarins and derivatives class.",206.19,"487-06-9",41,198.85,0,0,"http://selleckchem.com/products/citropten.html","C11H10O4","free base","5,7-Dimethoxycoumarin, Citroptene, Limettin, Limetin","COC1=CC2=C(C=CC(=O)O2)C(=C1)OC",0,0,0,0]
["S5145","Protoporphyrin IX","f4","L1300-22","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Protoporphyrin IX (PPIX) is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway.",562.66,"553-12-8",100,177.73,0,0,"http://selleckchem.com/products/protoporphyrin-ix.html","C34H34N4O4","free base","PPIX","CC1=C2[NH]C(=C1CCC(O)=O)C=C3N=C(C=C4N=C(C=C5[NH]C(=C2)C(=C5C)C=C)C(=C4C)C=C)C(=C3CCC(O)=O)C",0,0,0,0]
["S5155","Raffinose","g4","L1300-22","in 10mM DMSO",null,"BP2019",null,"Gastroenterology","Others","Others","Raffinose (Melitose, Melitriose) is a complex carbohydrate, a trisaccharide composed of galactose, fructose, and glucose. It can be broken apart into galactose and sucrose via the enzyme alpha-galactosidase.",504.44,"512-69-6",100,198.24,0,0,"http://selleckchem.com/products/raffinose.html","C18H32O16","free base","Melitose, Melitriose","OCC1OC(OCC2OC(OC3(CO)OC(CO)C(O)C3O)C(O)C(O)C2O)C(O)C(O)C1O",-6.058,5,11,8]
["S5157","Thymol","h4","L1300-22","in 10mM DMSO","CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,EP9.2,JP17,BP2017,USP38-NF33,JP16",null,"Infection","Immunology & Inflammation related","Immunology & Inflammation","Thymol (2-isopropyl-5-methylphenol, IPMP), a naturally occurring monocyclic phenolic compound derived from Thymus vulgaris (Lamiaceae), has been reported to exhibit anti-inflammatory property in vivo and vitro.",150.22,"89-83-8",30,199.71,0,0,"http://selleckchem.com/products/thymol.html","C10H14O","free base","2-isopropyl-5-methylphenol, IPMP","CC(C)C1=CC=C(C)C=C1O",0,0,0,0]
["S5159","Doxycycline","a5","L1300-22","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,Ph.Int_6th,JP17,BP2017,IP2010","062450,062569,065032,065041,065053,065055,065070,065285,065353,065356,065377,065427,065454,065471,090855,091277,091406,091605,200065,201678,202778,203278,204234,204446,205115,207757,209165,209396,209582","Infection/Parasitology","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Bacterial,MMP","Microbiology","Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum) is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. Doxycycline is also a nonspecific matrix metalloproteinase (MMP) inhibitor.",444.43,"564-25-0",88,198.01,0,0,"http://selleckchem.com/products/doxycycline.html","C22H24N2O8","free base","Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum","CC1C2C(O)C3C(N(C)C)C(=C(C(N)=O)C(=O)C3(O)C(=C2C(=O)C4=C1C=CC=C4O)O)O",0,0,0,0]
["S5163","7-Methoxycoumarin","b5","L1300-22","in 10mM DMSO",null,"USP42-NF37",null,"Others","Others","Others","7-Methoxycoumarin (Herniarine), also known as Herniarin, is a methoxy derivative of coumarin and substrate for dealkylase. It has been used in the synthesis of anti-first-pass effect compounds and detergents.",176.17,"531-59-9",35,198.67,0,0,"http://selleckchem.com/products/7-methoxycoumarin.html","C10H8O3","free base","Herniarin, Herniarine","COC1=CC2=C(C=CC(=O)O2)C=C1",0,0,0,0]
["S5164","Chlorotetracycline","c5","L1300-22","in 10mM DMSO","CFDA",null,null,"Others","Anti-infection","Microbiology","Chlortetracycline is a tetracycline antibiotic and commonly used to treat conjunctivitis in cats.",478.88,"57-62-5",6,12.53,0,0,"http://selleckchem.com/products/chlorotetracycline.html","C22H23ClN2O8","free base","N/A","CN(C)C1C2CC3C(=C(O)C2(O)C(=O)C(=C1O)C(N)=O)C(=O)C4=C(C(=CC=C4O)Cl)C3(C)O",0,0,0,0]
["S5167","Benzyl cinnamate","d5","L1300-22","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Benzyl cinnamate (Cinnamein, Benzylcinnamoate, Benzyl 3-phenylpropenoate, Cinnamic acid benzyl ester), a flavouring agent isolated from various plant species, is used in heavy oriental perfumes and as a fixative.",238.28,"103-41-3",47,197.25,0,0,"http://selleckchem.com/products/benzyl-cinnamate.html","C16H14O2","free base","Cinnamein, Benzylcinnamoate, Benzyl 3-phenylpropenoate, Cinnamic acid benzyl ester","O=C(OCC1=CC=CC=C1)/C=C/C2=CC=CC=C2",0,0,0,0]
["S5174","Kojic acid","e5","L1300-22","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","Fungal,Tyrosinase","Proteases","Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.",142.11,"501-30-4",28,197.03,0,0,"http://selleckchem.com/products/kojic-acid.html","C6H6O4","free base","N/A","OCC1=CC(=O)C(=CO1)O",0,0,0,0]
["S5176","Fructose","f5","L1300-22","in 10mM DMSO","DMF,NDC,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8,KP Ⅹ,JP17,BP2015,IP2010",null,"Gastroenterology","Others","Others","Fructose (D-(-)-Fructose, Fruit sugar, levulose, fructosteril, D-fructofuranose, D-arabino-hexulose) is a simple ketonic monosaccharide found in many plants.",180.16,"57-48-7",36,199.82,-1,0,"http://www.selleckchem.com/products/fructose.html","C6H12O6","Free Base","D-(-)-Fructose, Fruit sugar, levulose, fructosteril, D-fructofuranose, D-arabino-hexulose","OCC(O)C(O)C(O)C(=O)CO",-2.874,1,5,5]
["S5177","Naproxen","g5","L1300-22","in 10mM DMSO","DMF,NDC,FDA,CFDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,BP2017,IP2010,JP16,CP2005","074105,074110,074111,074121,074129,074140,074163,074182,074190,074201,074207,074211,074216,074263,074410,074457,074936,075061,075227,075337,075390,075927,076494,077339,078250,078620,091305,091416,091432,200429","Inflammation","COX","Immunology & Inflammation","Naproxen is an anti-inflammatory agent with analgesic and antipyretic properties. It is a nonselective inhibitor of COX-1 and COX-2.",230.26,"22204-53-1",46,199.77,-1,0,"http://www.selleckchem.com/products/naproxen.html","C14H14O3","Free Base","N/A","COC1=CC2=CC=C(C=C2C=C1)C(C)C(O)=O",2.849,2,0,3]
["S5179","Ropivacaine Mesilate","h5","L1300-22","in 10mM DMSO","DMF,NDC,FDA,HMA,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","078601,090194,090318,203955,204636,205612,206166,207636,210102","Neurological Disease","Others","Others","Ropivacaine Mesilate is the mesylate form of ropivacaine, which is a member of the amino amide class of local anesthetics.",370.51,"854056-07-8",74,199.72,-1,0,"http://www.selleckchem.com/products/ropivacaine-mesilate.html","C18H30N2O4S","Mesilate","Ropivacaine Mesylate","CCCN1CCCCC1C(=O)NC2=C(C)C=CC=C2C.C[S](O)(=O)=O",3.44,1,1,4]
["S5200","Diaveridine","a6","L1300-22","in 10mM DMSO",null,"USP42-NF37;Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","DHFR","Metabolism","Diaveridine (AI3-23935, CCRIS-3784) is coccidiostat with anti-parasitic activity and also a dihydrofolate reductase (DHFR) inhibitor preventing folic acid synthesis in species of Pneumocystis.",260.29,"5355-16-8",25,96.05,0,0,"http://selleckchem.com/products/diaveridine.html","C13H16N4O2","free base","AI3-23935, CCRIS-3784","COC1=C(OC)C=C(CC2=CN=C(N)N=C2N)C=C1",1.559,4,2,4]
["S5203","Sulbutiamine","b6","L1300-22","in 10mM DMSO","marketed in France","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Vitamin","Metabolism","Sulbutiamine is a synthetic derivative of thiamine (vitamin B1), belonging to a class of supplements shown to help improve memory, learning capacity, decision-making, concentration, and focus.",702.89,"3286-46-2",100,142.27,-1,-1.42,"https://www.selleckchem.com/products/sulbutiamine.html","C32H46N8O6S2","free base","Bisibutiamine, Vitaberin, Youvitan","CC(C)C(=O)OCCC(/SS\\C(CCOC(=O)C(C)C)=C(C)/N(CC1=C(N)N=C(C)N=C1)C=O)=C(C)/N(CC2=CN=C(C)N=C2N)C=O",1.356,10,2,19]
["S5205","Nilotinib hydrochloride","c6","L1300-22","in 10mM DMSO","FDA,DMF,PMDA","Martindale:The Extra Pharmacopoeia,EP9.8","022068","Cancer/Hematology","Bcr-Abl","Angiogenesis","Nilotinib hydrochloride (AMN-107) is the hydrochloride salt form of nilotinib, an orally bioavailable Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity.",565.98,"923288-95-3",100,176.69,-1,-1.77,"http://selleckchem.com/products/nilotinib-hydrochloride.html","C28H22F3N7O.HCl","hydrochloride","AMN-107 HCl","Cl.CC1=C[N](C=N1)C2=CC(=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C)C(=C3)NC4=NC=CC(=N4)C5=CC=CN=C5",5.466,5,2,7]
["S5206","Benzylpenicillin potassium","d6","L1300-22","in 10mM DMSO","CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.2,Ph.Int_6th,BP2017,IP2010,CP2005",null,"Infection/Inflammation","Antibiotics","Microbiology","Benzylpenicillin potassium (Penicillin G potassium) is the potassium salt form of penicillin G, a broad-spectrum penicillin antibiotic.",372.48,"113-98-4",74,198.67,0,0,"http://selleckchem.com/products/benzylpenicillin-potassium.html","C16H17N2O4S.K","potassium salt","Penicillin G potassium","[K+].CC1(C)SC2C(NC(=O)CC3=CC=CC=C3)C(=O)N2C1C([O-])=O",-0.35,2,1,4]
["S5208","Ciprofloxacin hydrochloride hydrate","e6","L1300-22","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","KP Ⅹ,JP17","074124,075593,075685,075747,075817,075928,075939,076089,076126,076136,076138,076426,076555,076558,076593,076639,076673,076754,076794,076896,076912,077568,077689,077859,078598,204613,208921","Infection","Antibiotics,Bacterial","Microbiology","Ciprofloxacin Hydrochloride (Ciloxan, Ceprimax, Oftacilox,Bay-09867 hydrochloride hydrate) is the hydrochloride salt form of ciprofloxacin, which is an antibiotic used to treat a number of bacterial infections.",385.82,"86393-32-0",8,20.74,0,0,"http://selleckchem.com/products/ciprofloxacin-hydrochloride-hydrate.html","C17H18FN3O3.HCl.H2O","hydrochloride hydrate","Ciloxan, Ceprimax, Oftacilox,Bay-09867 hydrochloride hydrate","O.Cl.OC(=O)C1=CN(C2CC2)C3=C(C=C(F)C(=C3)N4CCNCC4)C1=O",-1.095,2,1,3]
["S5209","Enoxacin Sesquihydrate","f6","L1300-22","in 10mM DMSO","DMF",null,null,"Infection","Bacterial","Microbiology","Enoxacin sesquihydrate (Enoxacin hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.",347.34,"84294-96-2",4,11.52,0,0,"http://selleckchem.com/products/enoxacin-sesquihydrate.html","C15H17FN4O3.3/2H2O","sesquihydrate","Enoxacin hydrate","CCN1C=C(C(O)=O)C(=O)C2=C1N=C(N3CCNCC3)C(=C2)F",-0.749,3,1,3]
["S5210","Sulfamethazine Sodium Salt","g6","L1300-22","in 10mM DMSO","DMF,CFDA","USP42-NF37",null,"Infection/Inflammation","Anti-infection","Microbiology","Sulfamethazine (Sulfadimethyldiazine) is a sulfanilamide anti-infective agent used in the lifestock industry.",300.31,"1981-58-4",60,199.79,0,0,"http://selleckchem.com/products/sulfamethazine-sodium-salt.html","C12H13N4O2S.Na","sodium salt","Sulfadimethyldiazine Sodium Salt","CC1=CC(=NC(=N1)N([Na])[S](=O)(=O)C2=CC=C(N)C=C2)C",0.982,4,1,3]
["S5211","4-Aminosalicylic acid","h6","L1300-22","in 10mM DMSO","marketed in British","EP9.1,BP2017",null,"Infection","Bacterial","Microbiology","4-Aminosalicylic acid (Para-aminosalicylic acid, Aminosalicylic acid, 4-aminosalicylate) is an antitubercular agent with bacteriostatic activity against Mycobacterium tuberculosis.",153.14,"65-49-6",10,65.3,0,0,"http://selleckchem.com/products/4-aminosalicylic-acid.html","C7H7NO3","free base","Para-aminosalicylic acid, Aminosalicylic acid, 4-aminosalicylate","NC1=CC(=C(C=C1)C(O)=O)O",0.471,1,2,1]
["S5212","Imidazolidinyl Urea","a7","L1300-22","in 10mM DMSO","DMF","USP43-NF38",null,"Others","Anti-infection","Microbiology","Imidazolidinyl Urea (Imidurea) is an antimicrobial agent used as preservative in cosmetics.",388.29,"39236-46-9",77,198.31,0,0,"http://selleckchem.com/products/imidazolidinyl-urea.html","C11H16N8O8","free base","Imidurea","OCN1C(NC(=O)NCNC(=O)NC2N(CO)C(=O)NC2=O)C(=O)NC1=O",-4.009,6,8,6]
["S5213","Piroctone Olamine","b7","L1300-22","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Infection","Fungal","Microbiology","Piroctone Olamine (piroctone ethanolamine) is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff,fungal infections.",298.42,"68890-66-4",38,127.34,"<1",0,"http://selleckchem.com/products/piroctone-olamine.html","C14H23NO2.C2H7NO",0,"piroctone ethanolamine","CC(CC1=CC(=CC(=O)N1O)C)CC(C)(C)C.NCCO",2.064,1,2,5]
["S5214","Imidocarb dipropionate","c7","L1300-22","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","Anti-infection","Microbiology","Imidocarb is an antiprotozoal agent, used as dipropionate in the treatment of babesiosis and ehrlichiosis.",496.56,"55750-06-6",39,78.54,0,0,"http://selleckchem.com/products/Imidocarb-dipropionate.html","C19H20N6O.2C3H6O2","dipropionate","N/A","CCC(O)=O.CCC(O)=O.O=C(NC1=CC=CC(=C1)C2=NCCN2)NC3=CC=CC(=C3)C4=NCCN4",2.022,5,4,6]
["S5215","Abacavir (1592U89)","d7","L1300-22","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,Ph.Int_6th,BP2017,IP2010","207369,022293,022547,077844,077950,078119,078348,078742,091050,091294,091560,200733,201107,201570,206725","Infection","Reverse Transcriptase","Microbiology","Abacavir (1592U89, ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS.",286.33,"136470-78-5",57,199.07,0,0,"http://selleckchem.com/products/abacavir.html","C14H18N6O","free base","N/A","NC1=NC2=C(N=C[N]2C3CC(CO)C=C3)C(=N1)NC4CC4",0.769,3,3,4]
["S5217","Arformoterol Tartrate","e7","L1300-22","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","200293,207306","Inflammation/Respiratory Disease","Adrenergic Receptor","Neuronal Signaling","Arformoterol Tartrate is the tartrate salt of arformoterol, a long-acting beta-2 adrenergic agonist with bronchodilator activity.",494.49,"200815-49-2",99,200.21,-1,-2.02,"https://www.selleckchem.com/products/arformoterol-tartrate.html","C23H30N2O10","Tartrate","(R, R)-Formoterol","COC1=CC=C(CC(C)NCC(O)C2=CC(=C(O)C=C2)NC=O)C=C1.OC(C(O)C(O)=O)C(O)=O",-2.446,4,6,11]
["S5222","Coluracetam","f7","L1300-22","in 10mM DMSO","DMF",null,null,"Others","GluR","Neuronal Signaling","Coluracetam (BCI-540, MKC-231) is a nootropic belonging to the racetam family of drugs with cognitive enhancing and neuroprotective effects.",341.4,"135463-81-9",68,199.18,"<1",0,"http://selleckchem.com/products/coluracetam.html","C19H23N3O3","free base","MKC-231, BCI-540","CC1=C(C)C2=C(O1)N=C3CCCCC3=C2NC(=O)CN4CCCC4=O",1.975,4,1,3]
["S5224","Adrafinil","g7","L1300-22","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeiac",null,"Psychotic disorders","Others","Others","Adrafinil (benzhydrylsulfinylacetohydroxamic acid, adrafinyl, CRL-40028) is a mild central nervous system stimulant drug directly affecting CNS function. It is used to relieve excessive sleepiness and inattention in elderly patients.",289.35,"63547-13-7",57,196.99,0,0,"http://selleckchem.com/products/adrafinil.html","C15H15NO3S","free base","benzhydrylsulfinylacetohydroxamic acid, adrafinyl, CRL-40028","ONC(=O)C[S](=O)C(C1=CC=CC=C1)C2=CC=CC=C2",1.745,2,1,5]
["S5227","Erythromycin thiocyanate","h7","L1300-22","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,CP2005,USP36-NF31,BP2013,JP15",null,"Infection","Antibiotics,Bacterial","Microbiology","Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits and inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.",793.02,"7704-67-8",100,126.1,0,0,"http://selleckchem.com/products/erythromycin-thiocyanate.html","C37H67NO13.CHNS","thiocyanate","N/A","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)C(=O)C(C)C(O)C1(C)O.SC#N",2.337,8,3,7]
["S5228","Minoxidil sulphate","a8","L1300-22","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017,IP2010","071344,071345,071537,071796,071799,071826,071839,072709,091344","Angiology/Cardiovascular Disease","Others","Others","Minoxidil (U-58838) is a potent direct-acting peripheral vasodilator that reduces peripheral resistance and produces a fall in blood pressure.",289.31,"83701-22-8",57,197.02,0,0,"http://selleckchem.com/products/minoxidil-sulphate.html","C9H15N5O4S","free base","U-58838","NC1=NC(=CC(=N)N1O[S](O)(=O)=O)N2CCCCC2",0.35,2,1,3]
["S5229","Isosorbide dinitrate","b8","L1300-22","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","040009,040591,040723,084204,086031,086032,086033,086034,086054,086055,086066,086067,086166,086167,086168,086169,086221,086222,086223,086225,086923,086925,087537,087545,087564,087946,088088,089190,089191,089192,089367","Cardiovascular Disease","Guanylate Cyclase,NOS","Immunology & Inflammation","Isosorbide Dinitrate (ISDN, Sorbide nitrate, Sorbidnitrate, Isordil, Nitrosorbide) is the dinitrate salt form of isosorbide, an organic nitrate with vasodilator activity. Isosorbide Dinitrate is a medication used for heart failure, esophageal spasms, and to treat and prevent chest pain from not enough blood flow to the heart. Isosorbide Dinitrate can converte to nitric oxide (NO), an active intermediate compound which activates the enzyme guanylate cyclase (atrial natriuretic peptide receptor A).",236.14,"87-33-2",47,199.03,0,0,"http://selleckchem.com/products/isosorbide-dinitrate.html","C6H8N2O8","free base","Sorbide nitrate, Sorbidnitrate, Isordil, Nitrosorbide","[O-][N+](=O)OC1COC2C(COC12)O[N+]([O-])=O",3.413,4,0,4]
["S5233","Fenretinide (NSC 374551)","c8","L1300-22","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Cancer/Inflammation","Retinoid Receptor","Metabolism","Fenretinide (4-hydroxy(phenyl)retinamide, 4-HPR, MK-4016) is a synthetic derivative of retinoic acid that has a broad-spectrum of cytotoxic activity against primary tumor cells, cell lines, and/or xenografts of various cancers (including neuroblastoma). Fenretinide (4-hydroxy(phenyl)retinamide; 4-HPR) is a synthetic derivative of retinoic acid, fenretinide can bind to retinoic acid receptor (RAR) and retinoid X receptor (RXR) at concentrations necessary to induce cell death.",391.55,"65646-68-6",78,199.21,"<1",0,"http://selleckchem.com/products/fenretinide.html","C26H33NO2","free base","4-hydroxy(phenyl)retinamide, 4-HPR, MK-4016","CC1=C(\\C=C\\C(C)=C\\C=C\\C(C)=C\\C(=O)NC2=CC=C(O)C=C2)C(C)(C)CCC1",6.463,1,2,6]
["S5234","Nintedanib Ethanesulfonate Salt","d8","L1300-22","in 10mM DMSO","PMDA",null,null,"Cancer/Respiratory Disease","FGFR,PDGFR,VEGFR","Protein Tyrosine Kinase","Nintedanib (Intedanib, BIBF 1120) is a small molecule tyrosine-kinase inhibitor with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β, respectively.",649.76,"656247-18-6",100,153.9,100,153.9,"http://selleckchem.com/products/nintedanib-ethanesulfonate-salt.html","C31H33N5O4.C2H6O3S","ethanesulfonate","Intedanib, BIBF 1120","CC[S](O)(=O)=O.COC(=O)C1=CC2=C(C=C1)C(/C(=O)N2)=C(NC3=CC=C(C=C3)N(C)C(=O)CN4CCN(C)CC4)\\C5=CC=CC=C5",2.9,4,2,9]
["S5238","Solifenacin (YM905)","e8","L1300-22","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.3,EP9.2,BP2017","091464,202551,205483,205575,206817,207721,209239,209333,209719,209818,209839,210224,210281,210582,210688,211423,211657","Others","AChR","Neuronal Signaling","Solifenacin (YM905) is a competitive muscarinic receptor antagonist. The binding of acetylcholine to these receptors, particularly the M3 receptor subtype, plays a critical role in the contraction of smooth muscle.",362.46,"242478-37-1",72,198.64,-1,-2.76,"https://www.selleckchem.com/products/solifenacin.html","C23H26N2O2","free base",0,"O=C(OC1CN2CCC1CC2)N3CCC4=C(C=CC=C4)C3C5=CC=CC=C5",4.029,2,0,3]
["S5239","Paroxetine mesylate","f8","L1300-22","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","207139,207188","Psychotic disorders","Serotonin Transporter","Neuronal Signaling","Paroxetine Mesylate(BRL-29060A mesylate,FG-7051 mesylate) is the mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties.",425.47,"217797-14-3",85,199.78,-1,-2.35,"http://selleckchem.com/products/paroxetine-mesylate.html","C19H20FNO3.CH4O3S","Mesylate","BRL-29060A mesylate,FG-7051 mesylate","C[S](O)(=O)=O.FC1=CC=C(C=C1)C2CCNCC2COC3=CC=C4OCOC4=C3",2.815,3,1,4]
["S5240","Lenvatinib (E7080) Mesylate","g8","L1300-22","in 10mM DMSO","FDA,DMF",null,"206947","Cancer","c-Kit,c-RET,FGFR,PDGFR,VEGFR","Protein Tyrosine Kinase","Lenvatinib Mesylate (E7080) is a synthetic, orally available tyrosine kinase inhibitor that inhibits vascular endothelial growth factor receptor (VEGFR1-3), fibroblast growth factor receptor (FGFR1-4), platelet-derived growth factor receptor α (PDGFRα), stem cell factor receptor (Kit (c-Kit)), and rearranged during transfection (RET (c-RET)). Lenvatinib Mesylate has potential antineoplastic activity.",522.96,"857890-39-2",39,74.58,-1,-1.91,"http://selleckchem.com/products/lenvatinib-mesylate.html","C21H19ClN4O4.CH4O3S","Mesylate","E7080 mesylate","COC1=C(C=C2C(=CC=NC2=C1)OC3=CC(=C(NC(=O)NC4CC4)C=C3)Cl)C(N)=O.C[S](O)(=O)=O",2.418,5,3,6]
["S5241","Lapatinib ditosylate monohydrate","h8","L1300-22","in 10mM DMSO","DMF",null,null,"Cancer","HER2","Protein Tyrosine Kinase","Lapatinib ditosylate monohydrate (Lapatinib ditoluenesulfonate monohydrate, Lapatinib tosilate, Lapatinib tosilate hydrate)is a dual tyrosine kinase inhibitor which interrupts the HER2/neu and epidermal growth factor receptor (EGFR) pathways, used for treatment of solid tumours such as breast and lung cancer.",943.48,"388082-78-8",100,105.99,-1,-1.06,"https://www.selleckchem.com/products/lapatinib-ditosylate-monohydrate.html","C43H44ClFN4O11S3","ditosylate monohydrate","Lapatinib ditoluenesulfonate monohydrate, Lapatinib tosilate, Lapatinib tosilate hydrate","O.CC1=CC=C(C=C1)[S](O)(=O)=O.CC2=CC=C(C=C2)[S](O)(=O)=O.C[S](=O)(=O)CCNCC3=CC=C(O3)C4=CC5=C(C=C4)N=CN=C5NC6=CC(=C(OCC7=CC(=CC=C7)F)C=C6)Cl",9.132,6,2,13]
["S5243","Ruxolitinib Phosphate","a9","L1300-22","in 10mM DMSO","FDA,DMF,PMDA",null,"202192","Hematology","Apoptosis related,Autophagy,JAK,Mitophagy","JAK/STAT","Ruxolitinib Phosphate (INCB018424, INC424) is the phosphate salt form of Ruxolitinib. Ruxolitinib is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis.",404.36,"1092939-17-7",80,197.84,29,71.72,"http://selleckchem.com/products/ruxolitinib-phosphate.html","C17H18N6.H3O4P","phosphate","INCB018424, INC424","O[P](O)(O)=O.N#CCC(C1CCCC1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4",2.412,3,1,4]
["S5245","Raltegravir potassium","b9","L1300-22","in 10mM DMSO","FDA,DMF,EMA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4","022145,203045,205786,022145","Infection","Integrase","Microbiology","Raltegravir Potassium(MK-0518 potassium) is the orally bioavailable potassium salt of raltegravir, the first approved human immunodeficiency virus type 1 (HIV-1) integrase inhibitor.",482.51,"871038-72-1",96,198.96,"<1",0,"http://selleckchem.com/products/raltegravir-potassium.html","C20H20FN6O5.K","potassium salt","MK-0518 potassium","[K+].CN1C(=O)C(=C(N=C1C(C)(C)NC(=O)C2=NN=C(C)O2)C(=O)NCC3=CC=C(F)C=C3)[O-]",-0.994,7,2,6]
["S5246","Entecavir","c9","L1300-22","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","202122,205740,205824,206217,206226,206294,206652,206672,206745,206872,208721,208782","Infection","Reverse Transcriptase","Microbiology","Entecavir(BMS200475,SQ34676), a new deoxyguanine nucleoside analogue, is a selective inhibitor of the replication of the hepatitis B virus (HBV).",277.28,"142217-69-4",55,198.36,"<1",0,"https://www.selleckchem.com/products/s5246-entecavir.html","C12H15N5O3","free base","BMS200475,SQ34676","NC1=NC(=O)C2=C(N1)[N](C=N2)C3CC(O)C(CO)C3=C",-1.404,3,4,2]
["S5247","Selamectin","d9","L1300-22","in 10mM DMSO","EMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017",null,"Infection/Parasitology","Parasite","Microbiology","Selamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a  wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas.",769.96,"220119-17-5",100,129.88,0,0,"https://www.selleckchem.com/products/selamectin.html","C43H63NO11","free base","UK-124114","COC1CC(OC(C)C1O)OC/2C(C)\\C=C\\C=C\\3COC4/C(=N/O)C(=CC(C(=O)OC5CC(C\\C=C2C)OC6(CCC(C)C(O6)C7CCCCC7)C5)C34O)C",5.315,9,1,4]
["S5250","Darunavir","e9","L1300-22","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","Martindale:The Extra Pharmacopoeia","202136,206555,210254","Infection","COVID-19,HIV Protease","Proteases","Darunavir (TMC114,DRV) is a nonpeptidic HIV protease inhibitor, used to treat HIV infection.",547.66,"206361-99-1",100,182.6,"<1",0,"http://selleckchem.com/products/darunavir.html","C27H37N3O7S","free base","TMC114,DRV","CC(C)CN(CC(O)C(CC1=CC=CC=C1)NC(=O)OC2COC3OCCC23)[S](=O)(=O)C4=CC=C(N)C=C4",2.631,6,3,12]
["S5253","Cisapride (R 51619)","f9","L1300-22","in 10mM DMSO","FDA,DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2010","020210,020398,020767","Gastrointestinal Disease","5-HT Receptor","Neuronal Signaling","Cisapride (R 51619, Kaudalit, Kinestase, Prepulsid, Presid, Pridesia, Propulsid) is a nonselective 5-HT4 receptor agonist with gastroprokinetic effects.",465.95,"81098-60-4",93,199.59,"<1",0,"http://selleckchem.com/products/cisapride.html","C23H29ClFN3O4",0,"Kaudalit, Kinestase, Prepulsid, Presid, Pridesia, Propulsid","COC1CN(CCCOC2=CC=C(F)C=C2)CCC1NC(=O)C3=C(OC)C=C(N)C(=C3)Cl",2.785,4,2,9]
["S5254","Dasatinib hydrochloride","g9","L1300-22","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","202103","Cancer/Hematology","Bcr-Abl,kit,Src","Angiogenesis","Dasatinib hydrochloride (BMS-354825) is the hydrochloride salt form of dasatinib, an inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively.",524.47,"854001-07-3",100,190.67,11,20.97,"https://www.selleckchem.com/products/dasatinib-hydrochloride.html","C22H27Cl2N7O2S","hydrochloride","BMS-354825 HCl","Cl.CC1=NC(=CC(=N1)NC2=NC=C(S2)C(=O)NC3=C(C)C=CC=C3Cl)N4CCN(CCO)CC4",3.821,4,3,7]
["S5255","Nicardipine","h9","L1300-22","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,EP9.3,KP Ⅹ,JP17","022276,074439,074540,074642,074670,074928,078405,078714,090125,090534,090664,090671","Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Nicardipine is a potent calcium channel blockader with marked vasodilator action.",479.52,"55985-32-5",95,198.11,30,62.56,"https://www.selleckchem.com/products/nicardipine.html","C26H29N3O6",0,"YC-93","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OCCN(C)CC3=CC=CC=C3)C",3.488,4,1,11]
["S5256","Benproperine phosphate","a10","L1300-22","in 10mM DMSO","CFDA,PMDA",null,null,"Respiratory Disease","Actin,Microtubule Associated","Cytoskeletal Signaling","Benproperine phosphate (Blascorid, Pirexyl), a cough suppressant, is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. Benproperine phosphate attenuates the actin polymerization rate of action polymerization nucleation by impairing Arp2/3 function. Benproperine phosphate suppresses cancer cell migration and tumor metastasis.",407.44,"19428-14-9",60,147.26,81,198.8,"http://selleckchem.com/products/benproperine-phosphate.html","C21H27NO.H3O4P","phosphate","Blascorid, Pirexyl phosphate","CC(COC1=C(CC2=CC=CC=C2)C=CC=C1)N3CCCCC3.O[P](O)(O)=O",4.753,1,0,6]
["S5257","Doxapram","b10","L1300-22","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,BP2017,JP16","073529,076266","Inflammation/Respiratory Disease","Potassium Channel","Transmembrane Transporters","Doxapram is a central respiratory stimulant with a brief duration of action. Doxapram is a selective TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel inhibitor with EC50 of 410 nM, 37 μM, 9 μM, respectively.",378.51,"309-29-5",75,198.15,"<1",0,"http://selleckchem.com/products/doxapram.html","C24H30N2O2","free base","N/A","CCN1CC(CCN2CCOCC2)C(C1=O)(C3=CC=CC=C3)C4=CC=CC=C4",3.043,2,0,6]
["S5258","Revefenacin","c10","L1300-22","in 10mM DMSO","FDA,NDC",null,"210598","Inflammation/Respiratory Disease","AChR","Neuronal Signaling","Revefenacin (TD-4208, GSK-1160724) is a potent, lung-selective, long-acting muscarinic antagonist that may be for the treatment of respiratory disease.",597.75,"864750-70-9",100,167.29,"<1",0,"http://selleckchem.com/products/revefenacin.html","C35H43N5O4",0,"TD-4208, GSK-1160724","CN(CCN1CCC(CC1)OC(=O)NC2=CC=CC=C2C3=CC=CC=C3)C(=O)C4=CC=C(CN5CCC(CC5)C(N)=O)C=C4",3.833,4,2,11]
["S5261","Ufenamate","d10","L1300-22","in 10mM DMSO","PMDA",null,null,"Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Ufenamate (Butyl flufenamate, Flufenamic acid butyl ester, Fenazol) is an anthranilic acid derivative with anti-inflammatory activity.",337.34,"67330-25-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/ufenamate.html","C18H18F3NO2","free base","Butyl flufenamate, Flufenamic acid butyl ester, Fenazol","CCCCOC(=O)C1=CC=CC=C1NC2=CC(=CC=C2)C(F)(F)F",5.506,2,1,8]
["S5266","Stiripentol","e10","L1300-22","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","206709,207223","Neurological Disease","P450 (e.g. CYP17)","Metabolism","Stiripentol (BCX2600) is a third-generation anti-epileptic drug that enhances GABAergic neurotransmission. It is an inhibitor of cytochrome P450.",234.29,"49763-96-4",46,196.34,13,55.49,"http://selleckchem.com/products/stiripentol.html","C14H18O3",0,"BCX2600","CC(C)(C)C(O)/C=C/C1=CC=C2OCOC2=C1",2.955,2,1,3]
["S5273","Canrenone","f10","L1300-22","in 10mM DMSO","marketed in Europe","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease/Metabolic Disease","Mineralocorticoid Receptor","Endocrinology & Hormones","Canrenone (Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone), a cardiovascular drug, a sort of steroid, is spironolactone's major metabolite and has been widely used as a nonselective aldosterone receptor antagonist clinically to treat heart failure, high blood pressure, edema, liver ascites, and other cardiovascular diseases.",340.46,"976-71-6",68,199.73,0,0,"http://selleckchem.com/products/canrenone.html","C22H28O3","free base","Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone","CC12CCC(=O)C=C1C=CC3C2CCC4(C)C3CCC45CCC(=O)O5",3.519,3,0,0]
["S5278","Tedizolid (TR-700)","g10","L1300-22","in 10mM DMSO","FDA,EMA,NDC,PMDA",null,"205435,205436","Infection","Antibiotics,Bacterial","Microbiology","Tedizolid(TR-700) is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.",370.34,"856866-72-3",10,27,-1,-2.7,"https://www.selleckchem.com/products/tedizolid.html","C17H15FN6O3",0,0,"C[N]1N=NC(=N1)C2=CC=C(C=N2)C3=C(F)C=C(C=C3)N4CC(CO)OC4=O",1.784,6,1,4]
["S5279","Fendiline hydrochloride","h10","L1300-22","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Angiology/Cardiovascular Disease","Calcium Channel,Ras","Transmembrane Transporters","Fendiline hydrochloride is the hydrochloride salt form of Fendiline, which is an L-type calcium channel blocker and also a specific inhibitor of K-Ras plasma membrane targeting with no detectable effect on the localization of H- and N-Ras.",351.91,"13636-18-5",70,198.91,0,0,"http://selleckchem.com/products/fendiline-hydrochloride.html","C23H25N.HCl","hydrochloride","N/A","Cl.CC(NCCC(C1=CC=CC=C1)C2=CC=CC=C2)C3=CC=CC=C3",5.772,0,1,7]
["S5281","Dapiprazole Hydrochloride","a11","L1300-22","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia","019849,204902","Ophthalmology","Adrenergic Receptor","Neuronal Signaling","Dapiprazole Hydrochloride (Glamidolo Hydrochloride, Reversil Hydrochloride) is the hydrochloride salt form of dapiprazole, an alpha-adrenergic blocker used to reverse mydriasis after eye examination.",361.91,"72822-13-0",21,58.03,72,198.94,"http://selleckchem.com/products/dapiprazole-hydrochloride.html","C19H27N5.HCl","hydrochloride","Glamidolo Hydrochloride, Reversil Hydrochloride","Cl.CC1=C(C=CC=C1)N2CCN(CC2)CCC3=NN=C4CCCC[N]34",3.384,2,0,4]
["S5282","Lactitol monohydrate","b11","L1300-22","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,EP9.3,USP42-NF37,BP2017",null,"Others","Others","Others","Lactitol is an artificial sugar alcohol currently used as a bulk sweetener in calorie-controlled foods.",362.33,"81025-04-9",72,198.71,0,0,"http://selleckchem.com/products/lactitol-monohydrate.html","C12H24O11.H2O","hydrate","N/A","O.OCC(O)C(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)CO",-4.895,2,9,8]
["S5284","Adenosine 5'-monophosphate monohydrate","c11","L1300-22","in 10mM DMSO","DMF",null,null,"Others","AMPK","PI3K/Akt/mTOR","Adenosine 5'-monophosphate monohydrate (5'-Adenylic acid, 5'-AMP) is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK).",365.24,"18422-05-4",9,24.64,0,0,"http://selleckchem.com/products/adenosine-5-monophosphate-monohydrate.html","C10H14N5O7P.H2O","hydrate","5'-Adenylic acid, 5'-AMP","O.NC1=NC=NC2=C1N=C[N]2C3OC(CO[P](O)(O)=O)C(O)C3O",-2.16,5,3,4]
["S5286","Ramatroban","d11","L1300-22","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease/Immunology","Prostaglandin Receptor","Metabolism","Ramatroban (BAY u 3405) is a thromboxane A2(TxA2) receptor antagonist with Ki value of 10 to 13 nM. It also antagonizes a newly identified PGD2 receptor, CRTh2 expressed on the inflammatory cells.",416.47,"116649-85-5",83,199.29,"<1",0,"http://selleckchem.com/products/ramatroban.html","C21H21FN2O4S","free base","BAY u 3405","OC(=O)CC[N]1C2=C(CC(CC2)N[S](=O)(=O)C3=CC=C(F)C=C3)C4=CC=CC=C14",3.51,3,1,6]
["S5288","Estropipate","e11","L1300-22","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017","040135,040296,040359,081213,081214,081215,081216","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estropipate (Piperazine estrone sulfate, Estrone sulfate piperazine salt, Pipestrone) is a natural estrogenic substance composed of estrone sulfate and piperazine and is used mainly in menopausal hormone therapy in the treatment of menopausal symptoms.",436.56,"7280-37-7",87,199.28,-1,-2.29,"https://www.selleckchem.com/products/estropipate.html","C22H32N2O5S",0,"Piperazine estrone sulfate, Estrone sulfate piperazine salt, Pipestrone","CC12CCC3C(CCC4=C3C=CC(=C4)O[S](O)(=O)=O)C1CCC2=O.C5CNCCN5",2.751,2,2,2]
["S5289","Ceftezole","f11","L1300-22","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,CP2005",null,"Infection","Bacterial","Microbiology","Ceftezole (Celoslin, Falomesin) is a semi-synthetic first-generation cephalosporin with antibacterial activity.",440.48,"26973-24-0",88,199.78,0,0,"http://selleckchem.com/products/ceftezole.html","C13H12N8O4S3","free base","Celoslin, Falomesin","OC(=O)C1=C(CSC2C(NC(=O)C[N]3C=NN=N3)C(=O)N12)CSC4=NN=CS4",-1.594,8,1,7]
["S5291","sulfaisodimidine","g11","L1300-22","in 10mM DMSO","marketed in Bristish",null,null,"Infection","Bacterial","Microbiology","Sulfaisodimidine (Sulfamethin) is a sulfonamide antibacterial.",278.33,"515-64-0",55,197.61,0,0,"http://selleckchem.com/products/sulfaisodimidine.html","C12H14N4O2S","free base","Sulfamethin, Sulfaisodimidine","CC1=CC(=NC(=N1)C)N[S](=O)(=O)C2=CC=C(N)C=C2",0.569,4,2,3]
["S5292","Diazolidinyl urea","h11","L1300-22","in 10mM DMSO","DMF",null,null,"Others","Anti-infection","Microbiology","Diazolidinyl urea (Germall II) is an antimicrobial preservative used in cosmetics.",278.22,"78491-02-8",55,197.69,0,0,"http://selleckchem.com/products/diazolidinyl-urea.html","C8H14N4O7","free base","Germall II","OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O",-3.165,3,5,5]
["S5293","Nimustine Hydrochloride","a2","L1300-23","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Cancer","DNA/RNA Synthesis","DNA Damage/DNA Repair","Nimustine Hydrochloride (Nidran) is the hydrochloride salt of nimustine, a nitrosourea with antineoplastic activity that alkylates and crosslinks DNA, thereby causing DNA fragmentation, inhibition of protein synthesis, and cell death.",309.15,"55661-38-6",61,197.32,0,0,"http://selleckchem.com/products/nimustine-hydrochloride.html","C9H13ClN6O2.HCl","hydrochloride","Nidran hydrochloride","Cl.CC1=NC=C(CNC(=O)N(CCCl)N=O)C(=N1)N",0.47,4,2,5]
["S5294","Cephalotin acid","b2","L1300-23","in 10mM DMSO","FDA,DMF",null,"062426","Infection","Antibiotics","Microbiology","Cephalotin acid (Cephalothin, Cefalotin, Cephalothinum) is a cephalosporin antibiotic.",396.44,"153-61-7",79,199.27,0,0,"http://selleckchem.com/products/cephalotin-acid.html","C16H16N2O6S2","free base","Cephalothin, Cefalotin, Cephalothinum","CC(=O)OCC1=C(N2C(SC1)C(NC(=O)CC3=CC=CS3)C2=O)C(O)=O",0.407,5,1,7]
["S5295","Lincomycin Hydrochloride Monohydrate","c2","L1300-23","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Infection","Antibiotics,Antibiotics for Mammalian Cell Culture","Microbiology","Lincomycin hydrochloride monohydrate is a narrow-spectrum antibiotic used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.",461.01,"7179-49-9",92,199.56,0,0,"http://selleckchem.com/products/lincomycin-hydrochloride-monohydrate.html","C18H34N2O6S.HCl.H2O","hydrochloride, hydrate","N/A","O.Cl.CCCC1CC(N(C)C1)C(=O)NC(C(C)O)C2OC(SC)C(O)C(O)C2O",0.247,2,5,7]
["S5297","Vidarabine monohydrate","d2","L1300-23","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia","050486,050523","Infection","DNA/RNA Synthesis","DNA Damage/DNA Repair","Vidarabine (Spongoadenosine, Vira-A) is a nucleoside antibiotic with antiviral acitivity that interferes with the synthesis of viral DNA. It is used to treat herpes simplex and varicella zoster viruses.",285.26,"24356-66-9",57,199.82,0,0,"http://selleckchem.com/products/vidarabine-monohydrate.html","C10H13N5O4.H2O","hydrate","Spongoadenosine monohydrate, Vira-A monohydrate","O.NC1=NC=NC2=C1N=C[N]2C3OC(CO)C(O)C3O",-2.088,4,4,2]
["S5298","Amoxicillin trihydrate","e2","L1300-23","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,Ph.Int_6th,BP2017,IP2010",null,"Infection","Antibiotics,Bacterial","Microbiology","Amoxicillin (Amoxil, Amoxipen, Moxaline) is a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity.",419.45,"61336-70-7",30,71.52,0,0,"http://selleckchem.com/products/amoxicillin-trihydrate.html","C16H19N3O5S.3H2O","trihydrate","Amoxil trihydrate, Amoxipen trihydrate, Moxaline trihydrate","O.O.O.CC1(C)SC2C(NC(=O)C(N)C3=CC=C(O)C=C3)C(=O)N2C1C(O)=O",-3.161,3,3,4]
["S5299","Tosufloxacin p-Toluenesulfonate Hydrate","f2","L1300-23","in 10mM DMSO","CFDA",null,null,"Others","Antibiotics","Microbiology","Tosufloxacin (T-3262) is a fluoroquinolone antibiotic that is used to treat susceptible infections.",594.56,"1400591-39-0",100,168.19,0,0,"http://selleckchem.com/products/tosufloxacin-p-toluenesulfonate-hydrate.html","C19H15F3N4O3.C7H8O3S.H2O","4-methylbenzenesulfonate, hy","Tosufloxacin Tosylate Hydrate, T-3262 Tosylate Hydrate","O.CC1=CC=C(C=C1)[S](O)(=O)=O.NC2CCN(C2)C3=NC4=C(C=C3F)C(=O)C(=CN4C5=CC=C(F)C=C5F)C(O)=O",1.5,3,1,4]
["S5301","Carglumic Acid","g2","L1300-23","in 10mM DMSO","FDA,DMF,HMA,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","022562","Metabolic Disease","CPSase","Metabolism","Carglumic Acid (arbamylglutamic acid, Carbamino-L-glutamic acid, Ureidoglutaric acid, N-Carbamylglutamate) is an orally active, synthetic structural analogue of N-acetylglutamate (NAG) and carbamoyl phosphate synthetase 1 (CPS 1) activator, with ammonia lowering activity.",190.15,"1188-38-1",38,199.84,-1,0,"http://www.selleckchem.com/products/carglumic-acid.html","C6H10N2O5","Free Base","Carbamylglutamic acid, Carbamino-L-glutamic acid, Ureidoglutaric acid, N-Carbamylglutamate","NC(=O)NC(CCC(O)=O)C(O)=O",-1.169,3,2,5]
["S5302","6-Methoxy-2-naphthoic acid","h2","L1300-23","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","NMDAR","Neuronal Signaling","6-Methoxy-2-naphthoic acid (6-Methoxy-2-naphthalenecarboxylic acid) is an modulator of NMDAR.",202.21,"2471-70-7",40,197.81,"<1",0,"http://selleckchem.com/products/6-methoxy-2-naphthoic-acid.html","C12H10O3","free base","6-Methoxy-2-naphthalenecarboxylic acid","COC1=CC2=CC=C(C=C2C=C1)C(O)=O",2.351,2,0,2]
["S5305","Bromisoval","a3","L1300-23","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Others","Others","Bromisoval (Bromovalerylurea, Isobromyl, Bromaral, BRN 1773255) is a hypnotic and sedative of the bromoureide group with anti-inflammatory effects.",223.07,"496-67-3",44,197.25,0,0,"http://selleckchem.com/products/bromisoval.html","C6H11BrN2O2","free base","Bromovalerylurea, Isobromyl, Bromaral, BRN 1773255, 2-Bromo-N-carbamoyl-3-methylbutanamide","CC(C)C(Br)C(=O)NC(N)=O",0.952,2,2,2]
["S5309","Propyphenazone (4-Isopropylantipyrine)","b3","L1300-23","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017",null,"Neurological Disease","COX","Immunology & Inflammation","Propyphenazone(4-Isopropylantipyrine, Isopropyrine), an analgesic and antipyretic agent, is a selective cyclooxygenase-2 inhibitor with anti-inflammatory activity.",230.31,"479-92-5",46,199.73,0,0,"http://selleckchem.com/products/propyphenazone.html","C14H18N2O","free base","Isopropylantipyrine, Isopropyrine","CC(C)C1=C(C)N(C)N(C2=CC=CC=C2)C1=O",2.373,1,0,2]
["S5311","Pyridoxal phosphate","c3","L1300-23","in 10mM DMSO","DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37",null,"Nutritional support","Vitamin","Metabolism","Pyridoxal phosphate (Pyridoxal 5'-phosphate, PAL-P, PLP, Vitamin B6), the active form of vitamin B6, acts as a coenzyme in all transamination reactions, and in certain decarboxylation, deamination, and racemization reactions of amino acids.",247.14,"54-47-7",10,40.46,6,24.28,"http://selleckchem.com/products/pyridoxal-phosphate.html","C8H10NO6P","free base","pyridoxal 5'-phosphate, PAL-P, PLP, Vitamin B6 phosphate","CC1=NC=C(CO[P](O)(O)=O)C(=C1O)C=O",-0.197,3,1,4]
["S5320","Octinoxate","d3","L1300-23","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","020045","Others","Others","Others","Octinoxate (Octyl methoxycinnamate, ethylhexyl methoxycinnamate) is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage.",290.4,"5466-77-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/octinoxate.html","C18H26O3","free base","Octyl methoxycinnamate, ethylhexyl methoxycinnamate","CCCCC(CC)COC(=O)C=CC1=CC=C(OC)C=C1",5.153,3,0,10]
["S5322","Sodium gualenate","e3","L1300-23","in 10mM DMSO","PMDA",null,null,"Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Sodium gualenate (Guaiazulenesulfonate sodium), a hydrophilic derivative of guaiazulene (GA), is an unstable compound, which is gradually decomposed in the solid state at room temperature. It has anti-inflammatory and wound-healing effects.",300.35,"6223-35-4",60,199.77,18,59.93,"http://selleckchem.com/products/sodium-gualenate.html","C15H17O3S.Na","sodium salt","Guaiazulenesulfonate sodium","[Na+].CC(C)C1=CC=C(C)C2=C(C=C(C)C2=C1)[S]([O-])(=O)=O",1.993,0,0,2]
["S5325","Nitisinone","f3","L1300-23","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","209449,021232,206356","Metabolic Disease","Others","Metabolism","Nitisinone (NTBC, Nitisone, SC0735) is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase used in the treatment of hereditary tyrosinemia type 1.",329.23,"104206-65-7",65,197.43,"<1",0,"http://selleckchem.com/products/nitisinone.html","C14H10F3NO5","free base","NTBC, Nitisone, SC0735","[O-][N+](=O)C1=CC(=CC=C1C(=O)C2C(=O)CCCC2=O)C(F)(F)F",2.53,3,0,4]
["S5326","Dolasetron","g3","L1300-23","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","020623,020624","Gastroenterology","5-HT Receptor","Neuronal Signaling","Dolasetron(MDL-73147EF) is a highly specific and selective serotonin 5-HT3 receptor antagonist. It has minimal activity at other known serotonin receptors, and has low affinity for dopamine receptors.",324.37,"115956-12-2",64,197.31,"<1",0,"https://www.selleckchem.com/products/dolasetron.html","C19H20N2O3","free base","MDL-73147EF","O=C1CN2C3CC(CC2CC1C3)OC(=O)C4=C[NH]C5=C4C=CC=C5",2.035,3,1,3]
["S5327","Meisoindigo","h3","L1300-23","in 10mM DMSO","CFDA",null,null,"Cancer","Others","Apoptosis","Meisoindigo (N-Methylisoindigotin, Methylisoindigotin, Dian III), a derivative of Indigo naturalis, is an active compound of a Chinese anti-leukemia medicine that has been effectively used in the treatment of chronic myelogenous leukemia (CML). In vitro cell line studies have shown that this agent might induce apoptosis and myeloid differentiation of acute myeloid leukemia (AML).",276.29,"97207-47-1",55,199.07,"<1",0,"http://selleckchem.com/products/meisoindigo.html","C17H12N2O2","free base","N-Methylisoindigotin, Methylisoindigotin, Dian III","CN1C(=O)/C(C2=C1C=CC=C2)=C3/C(=O)NC4=CC=CC=C34",1.851,2,1,0]
["S5328","Gamithromycin","a4","L1300-23","in 10mM DMSO","EMA",null,null,"Infection","Antibiotics","Microbiology","Gamithromycin (ML-1709460) is a new macrolide antibiotic that is only registered for use in cattle to treat respiratory disorders such as bovine respiratory disease.",777.04,"145435-72-9",100,128.69,"<1",0,"http://www.selleckchem.com/products/gamithromycin.html","C40H76N2O12","Free Base","ML-1709460","CCCN1CC(C)C(O)C(C)(O)C(CC)OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC1C",2.562,7,3,9]
["S5331","Ceftezole sodium","b4","L1300-23","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Infection","Bacterial","Microbiology","Ceftezole Sodium (Celoslin sodium, Falomesin sodium) is the sodium salt form of ceftezole, a semi-synthetic first-generation cephalosporin with antibacterial activity.",462.46,"41136-22-5",92,198.94,92,198.94,"http://selleckchem.com/products/ceftezole-sodium.html","C13H11N8O4S3.Na","sodium salt","Celoslin sodium, Falomesin sodium","[Na+].[O-]C(=O)C1=C(CSC2C(NC(=O)C[N]3C=NN=N3)C(=O)N12)CSC4=NN=CS4",-3.068,7,1,7]
["S5333","Sulbenicillin Sodium","c4","L1300-23","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Infection","Antibiotics","Microbiology","Sulbenicillin Sodium (Sulfocillin, Sulfobenzylpenicillin) is the sodium salt of sulbenicillin, which is a penicillin antibiotic.",458.42,"28002-18-8",91,198.51,91,198.51,"http://selleckchem.com/products/sulbenicillin-sodium.html","C16H16N2O7S2.2Na","sodium salt","Sulfocillin, Sulfobenzylpenicillin","[Na+].[Na+].CC1(C)SC2C(NC(=O)C(C3=CC=CC=C3)[S]([O-])(=O)=O)C(=O)N2C1C([O-])=O",-3.303,2,1,5]
["S5339","4-Allylanisole","d4","L1300-23","in 10mM DMSO","DMF","EP10.4",null,"Neurological Disease","Others","Others","4-Allylanisole (Estragole, p-Allylanisole, Methyl chavicol) is a natural organic compound that is a component of various trees and plants. It is used in the preparation of fragrances.",148.2,"140-67-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/4-allylanisole.html","C10H12O","free base","Estragole, p-Allylanisole, Methyl chavicol","COC1=CC=C(CC=C)C=C1",2.821,1,0,3]
["S5341","Metroprolol succinate","e4","L1300-23","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA",null,"076640,076862,076969,077176,077298,077779,078889,090615,090617,202033,203894,204106,204161,207206,207465","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Metroprolol Succinate (Metoprolol succinate) is the succinate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity.",652.82,"98418-47-4",100,153.18,100,153.18,"http://selleckchem.com/products/metroprolol-succinate.html","C34H56N2O10","succinate","Metoprolol succinate","COCCC1=CC=C(OCC(O)CNC(C)C)C=C1.COCCC2=CC=C(OCC(O)CNC(C)C)C=C2.OC(=O)CCC(O)=O",-2.255,6,4,21]
["S5343","Vanillic acid","f4","L1300-23","in 10mM DMSO",null,"BP2010",null,"Infection/Inflammation","NF-κB","NF-κB","Vanillic acid (4-hydroxy-3-methoxybenzoic acid) is a flavoring agent which is also an intermediate in the production of vanillin from ferulic acid. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects.",168.15,"121-34-6",33,196.25,0,0,"http://selleckchem.com/products/vanillic-acid.html","C8H8O4","free base","4-hydroxy-3-methoxybenzoic acid","COC1=C(O)C=CC(=C1)C(O)=O",1.201,2,1,2]
["S5345","(+/-)-nerolidol","g4","L1300-23","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cancer/Inflammation/Parasite","Parasite","Microbiology","(+/-)-nerolidol is a naturally occurring sesquiterpene found in the essential oils of many types of plants and flowers. It has diverse range of pharmacological and biological activities including antioxidant, anti-microbial, anti-biofilm, anti-parasitic, insecticidal, anti-ulcer, skin penetration enhancer, anti-tumor, anti-nociceptive and anti-inflammatory properties.",222.37,"7212-44-4","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/nerolidol.html","C15H26O","free base","Peruviol","CC(C)=CCC/C(C)=C/CCC(C)(O)C=C",4.561,0,0,7]
["S5350","Cefpodoxime proxetil","h4","L1300-23","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17","065082,065083,065370,065388,065409,065462,090031","Infection","Antibiotics,Bacterial","Microbiology","Cefpodoxime Proxetil is a third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity.",557.6,"87239-81-4",100,179.34,"<1",0,"http://selleckchem.com/products/cefpodoxime-proxetil.html","C21H27N5O9S2","free base","N/A","COCC1=C(N2C(SC1)C(NC(=O)C(=N/OC)\\C3=CSC(=N3)N)C2=O)C(=O)OC(C)OC(=O)OC(C)C",0.715,11,2,13]
["S5351","Cefmetazole sodium","a5","L1300-23","in 10mM DMSO","FDA,DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17,USP39-NF34,","050637,050683","Infection","Antibiotics","Microbiology","Cefmetazole sodium is a semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms.",493.52,"56796-39-5",98,198.57,98,198.57,"https://www.selleckchem.com/products/cefmetazole-sodium.html","C15H16N7O5S3.Na","sodium salt","Sodium cefmetazole","[Na+].COC1(NC(=O)CSCC#N)C2SCC(=C(N2C1=O)C([O-])=O)CSC3=NN=N[N]3C",-2.179,6,1,9]
["S5352","Cefminox Sodium","b5","L1300-23","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Infection","Bacterial","Microbiology","Cefminox Sodium (Meicelin, MT-141) is the sodium salt form of cefminox, a semi-synthetic, second-generation, beta-lactamase-stable cephalosporin with antibacterial activity.",541.56,"75498-96-3",100,184.65,100,184.65,"http://selleckchem.com/products/cefminox-sodium.html","C16H20N7O7S3.Na","sodium salt","Meicelin, MT-141","[Na+].COC1(NC(=O)CSCC(N)C(O)=O)C2SCC(=C(N2C1=O)C([O-])=O)CSC3=NN=N[N]3C",-5.601,7,2,11]
["S5353","Cefpiramide sodium","c5","L1300-23","in 10mM DMSO","FDA,CFDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17","050633","Infection","Antibiotics,Bacterial","Microbiology","Cefpiramide sodium (CPMS, SM-1652,wy-44635) is an anionic β-lactam antibiotic. It exhibits antibacterial activity against gram-positive and gram-negative bacteria, in particular, to Pseudomonas aeruginosa, which can result in achronic life-threatening infection in the lungs of cystic fibrosis patients.",634.62,"74849-93-7",100,157.57,100,157.57,"http://selleckchem.com/products/cefpiramide-sodium.html","C25H23N8NaO7S2",0,"SM-1652, wy-44635","[Na+].C[N]1N=NN=C1SCC2=C(N3C(SC2)C(NC(=O)C(NC(=O)C4=C(O)C=C(C)N=C4)C5=CC=C(O)C=C5)C3=O)C([O-])=O",-1.425,7,4,9]
["S5356","Ceftiofur","d5","L1300-23","in 10mM DMSO","EMA","Martindale:The Extra Pharmacopoeia,USP42-NF37",null,"Infection","Bacterial","Microbiology","Ceftiofur is a semisynthetic, beta-lactamase-stable, broad-spectrum cephalosporin with antibacterial activity.",523.56,"80370-57-6",100,191,-1,-1.91,"http://selleckchem.com/products/ceftiofur.html","C19H17N5O7S3","free base","N/A","CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)CSC(=O)C3=CC=CO3)C4=CSC(=N4)N",0.708,8,2,9]
["S5357","Safinamide","e5","L1300-23","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"207145","Neurological Disease","MAO","Metabolism","Safinamide (EMD-1195686, PNU-15774E) is an orally active, selective, reversible <v>monoamine oxidase-B inhibitor with both dopaminergic and non-dopaminergic (glutamatergic) properties. The IC50 value of safinamide for MAO-B is 98 nM.",302.34,"133865-89-1",60,198.45,-1,-3.31,"http://selleckchem.com/products/safinamide.html","C17H19FN2O2","free base","EMD-1195686, PNU-15774E","CC(NCC1=CC=C(OCC2=CC=CC(=C2)F)C=C1)C(N)=O",2.478,2,2,7]
["S5358","Regadenoson","f5","L1300-23","in 10mM DMSO","FDA,DMF,EMA,NDC","Martindale:The Extra Pharmacopoeia","022161","Diagnosis","Adenosine Receptor","GPCR & G Protein","Regadenoson (CVT-3146, Lexiscan) is a selective A2A adenosine receptor agonist with coronary vasodilating activity.",390.35,"313348-27-5",56,143.46,"<1",0,"http://selleckchem.com/products/regadenoson.html","C15H18N8O5","free base","CVT-3146, Lexiscan","CNC(=O)C1=C[N](N=C1)C2=NC3=C(N=C[N]3C4OC(CO)C(O)C4O)C(=N2)N",-1.925,6,5,4]
["S5359","Butoconazole","g5","L1300-23","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","019881,019215,019359,020421,200923","Infection","Fungal","Microbiology","Butoconazole is an imidazole antifungal used in gynecology.",411.78,"64872-76-0",82,199.14,0,0,"http://selleckchem.com/products/butoconazole.html","C19H17Cl3N2S","free base","N/A","ClC1=CC=C(CCC(C[N]2C=CN=C2)SC3=C(Cl)C=CC=C3Cl)C=C1",6.496,1,0,7]
["S5360","Diflorasone","h5","L1300-23","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,JP17","075187,075331,075374,075508,076263,206572,207440,210753","Immunology/Infection","Immunology & Inflammation related","Immunology & Inflammation","Diflorasone acts as a corticosteroid hormone receptor agonist with anti-inflammatory and immunosuppressive properties.",410.45,"2557-49-5",82,199.78,"<1",0,"https://www.selleckchem.com/products/diflorasone.html","C22H28F2O5","free base","N/A","CC1CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO",1.546,2,2,2]
["S5361","Bendazac","a6","L1300-23","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia",null,"Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Bendazac (bendazolic acid, AF-983) is a non-steroidal anti-inflammatory drug that delays the cataractogenic process. It may act by preventing protein denaturation.",282.29,"20187-55-7",56,198.37,"<1",0,"http://selleckchem.com/products/bendazac.html","C16H14N2O3","free base","bendazolic acid, AF-983","OC(=O)COC1=N[N](CC2=CC=CC=C2)C3=C1C=CC=C3",3.267,3,0,5]
["S5363","Pikamilone","b6","L1300-23","in 10mM DMSO","marketed in Russian",null,null,"Neurological Disease","Others","Others","Pikamilone is a drug having a central (vegetotropic and vascular) and peripheral (vasodilating) mechanisms of action.",208.21,"34562-97-5",33,158.49,0,0,"http://selleckchem.com/products/pikamilone.html","C10H12N2O3","free base","N/A","OC(=O)CCCNC(=O)C1=CN=CC=C1",-0.062,3,1,5]
["S5365","Alogliptin","c6","L1300-23","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"210073,210159,210172,210213,210240","Endocrinology/Metabolic Disease","DPP","Proteases","Alogliptin is a potent, selective inhibitor of the serine protease dipeptidyl peptidase IV (DPP-4) with IC50 values of 2.63 nM and exhibits greater than 10,000 fold selectivity over the closely related serine proteases DPP-8 and DPP-9.",339.39,"850649-61-5",67,197.41,18,53.04,"http://selleckchem.com/products/alogliptin.html","C18H21N5O2",0,"SYR 322","CN1C(=O)C=C(N2CCCC(N)C2)N(CC3=CC=CC=C3C#N)C1=O",1.271,2,1,3]
["S5366","Fipronil","d6","L1300-23","in 10mM DMSO","EMA","Martindale:The Extra Pharmacopoeia",null,"Others","Anti-infection","Microbiology","Fipronil (Fluocyanobenpyrazole, Termidor) is a recalcitrant phenylpyrazole-based pesticide used for flea/tick treatment and termite control that is distributed in urban aquatic environments via stormwater and contributes to stream toxicity.",437.15,"120068-37-3",87,199.02,0,0,"http://selleckchem.com/products/fipronil.html","C12H4Cl2F6N4OS","free base","Fluocyanobenpyrazole, Termidor","NC1=C(C(=N[N]1C2=C(Cl)C=C(C=C2Cl)C(F)(F)F)C#N)[S](=O)C(F)(F)F",5.579,2,1,4]
["S5367","Ethyl Oleate","e6","L1300-23","in 10mM DMSO",null,"BP2015;USP38-NF33;IP2010;Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Ethyl Oleate (Oleic acid ethyl ester) is a fatty acid ester formed by the condensation of oleic acid and ethanol, usually used as a solvent for pharmaceutical drug preparations.",310.51,"111-62-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/ethyl-oleate.html","C20H38O2","free base","Oleic acid ethyl ester","CCCCCCCC\\C=C/CCCCCCCC(=O)OCC",7.435,2,0,17]
["S5368","Lactitol","f6","L1300-23","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8,KP Ⅹ,BP2015",null,"Others","Others","Others","Lactitol is a versatile, reduced calorie sweetener derived from natural milk sugar, used in a wide variety of sweetening applications.",344.31,"585-86-4",68,197.5,0,0,"http://selleckchem.com/products/lactitol.html","C12H24O11","free base","N/A","OCC(O)C(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)CO",-4.688,2,9,8]
["S5369","Ethoxyquin","g6","L1300-23","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","HSP (HSP90)","Cytoskeletal Signaling","Ethoxyquin (Santoquin, Santoflex, Quinol) is an antioxidant used as a food preservative.  Ethoxyquin is an antioxidant which has been used in animal feed for many years and also an inhibitor of heat shock protein 90 (Hsp90).",217.31,"91-53-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",10,0,0,"http://selleckchem.com/products/ethoxyquin.html","C14H19NO","free base","Santoquin, Santoflex, Quinol","CCOC1=CC2=C(NC(C)(C)C=C2C)C=C1",3.221,1,1,2]
["S5371","Ajmaline","h6","L1300-23","in 10mM DMSO","marketed in Germany","Martindale:The Extra Pharmacopoeia,JP17",null,"Cardiovascular Disease","Potassium Channel","Transmembrane Transporters","Ajmaline (Cardiorythmine, Tachmalin), found in the root of Rauwolfia serpentina, is a class Ia antiarrhythmic agent.",326.43,"4360-12-7",65,199.12,-1,-3.06,"https://www.selleckchem.com/products/ajmaline.html","C20H26N2O2","free base","Cardiorythmine, Tachmalin","CCC1C(O)N2C3CC1C4C(O)C5(CC24)C3N(C)C6=CC=CC=C56",1.932,0,2,1]
["S5372","Methyl Aminolevulinate Hydrochloride","a7","L1300-23","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia","021415","Others","Others","Others","Methyl Aminolevulinate (Aminolevulinic acid methyl ester Hydrochloride, Methyl 5-aminolevulinate Hydrochloride) is a prodrug that is metabolised to protoporphyrin IX used in photodynamic therapy.",181.62,"79416-27-6",36,198.22,-1,-5.51,"https://www.selleckchem.com/products/methyl-aminolevulinate-hydrochloride.html","C6H12ClNO3","free base","Aminolevulinic acid methyl ester Hydrochloride, Methyl 5-aminolevulinate Hydrochloride","Cl.COC(=O)CCC(=O)CN",-0.613,3,1,5]
["S5377","Dibutyl phthalate","b7","L1300-23","in 10mM DMSO",null,"EP9.2;BP2017;USP40-NF35;IP2010;Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","Others","Others","Dibutyl phthalate is widely used as plasticizer in numerous kinds of products such as plastic packaging in food industries.",278.34,"84-74-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/dibutyl-phthalate.html","C16H22O4","free base","N/A","CCCCOC(=O)C1=C(C=CC=C1)C(=O)OCCCC",4.198,4,0,10]
["S5378","Dimethyl phthalate","c7","L1300-23","in 10mM DMSO",null,"USP42-NF37;BP2019;IP2010;Martindale:The Extra Pharmacopoeia",null,"Parasite","Others","Others","Dimethyl phthalate is an organic compound, used as an insect repellent for mosquitoes and flies.",194.18,"131-11-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/dimethyl-phthalate.html","C10H10O4",0,"N/A","COC(=O)C1=C(C=CC=C1)C(=O)OC",1.54,4,0,4]
["S5385","Imidafenacin","d7","L1300-23","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","AChR","GPCR & G Protein","Imidafenacin (KRP-197, ONO-8025) is a urinary antispasmodic of the anticholinergic class. It is a novel antimuscarinic agent with safety and efficacy, has been clinically used for the treatment of overactive bladder. Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM; less potent for M2 receptors(IC50=4.13 nM). IC50 value: 0.3 nM(M3).",319.4,"170105-16-5",63,197.24,-1,-3.13,"https://www.selleckchem.com/products/imidafenacin.html","C20H21N3O","free base","KRP-197, ONO-8025","CC1=NC=C[N]1CCC(C(N)=O)(C2=CC=CC=C2)C3=CC=CC=C3",2.55,2,1,6]
["S5388","Betrixaban","e7","L1300-23","in 10mM DMSO","FDA,EMA,NDC",null,"208383","Hematology","Factor Xa","Metabolism","Betrixaban is a new, long-acting, oral and selective Factor Xa inhibitor that decreases prothrombinase activity and thrombin generation.",451.91,"330942-05-7",35,77.45,"<1",0,"https://www.selleckchem.com/products/betrixaban.html","C23H22ClN5O3","free base","PRT054021","COC1=CC=C(NC(=O)C2=CC=C(C=C2)C(=N)N(C)C)C(=C1)C(=O)NC3=CC=C(Cl)C=N3",2.904,4,2,7]
["S5389","Betrixaban maleate","f7","L1300-23","in 10mM DMSO","FDA,EMA,NDC",null,"208383","Hematology","Factor Xa","Metabolism","Betrixaban maleate is the maleate salt form of Betrixaban, which is a Factor Xa inhibitor that decreases prothrombinase activity and thrombin generation.",567.98,"936539-80-9",100,176.06,1,1.76,"https://www.selleckchem.com/products/betrixaban-maleate.html","C23H22ClN5O3.C4H4O4","maleate","N/A","COC1=CC=C(NC(=O)C2=CC=C(C=C2)C(=N)N(C)C)C(=C1)C(=O)NC3=CC=C(Cl)C=N3.OC(=O)\\C=C/C(O)=O",2.943,6,2,9]
["S5392","Mepivacaine","g7","L1300-23","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,KP Ⅹ,JP17,BP2017","040806,083559,087509,088769,088770","Neurological Disease","Others","Others","Mepivacaine (Carbocaine) is a local anesthetic indicated for infiltration, nerve block, and epidural anesthesia.",246.35,"96-88-8",49,198.91,-1,-4.06,"https://www.selleckchem.com/products/mepivacaine.html","C15H22N2O","free base","Carbocaine","CN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",2.981,1,1,2]
["S5393","Cyclofenil","h7","L1300-23","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia",null,"Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Cyclofenil is a selective estrogen receptor modulator showing a higher affinity for ERβ than Erα.",364.43,"2624-43-3",21,57.62,0,0,"https://www.selleckchem.com/products/cyclofenil.html","C23H24O4","free base","F-6066; H-3452","CC(=O)OC1=CC=C(C=C1)[C](=[C]2CC[CH2]CC2)C3=CC=C(OC(C)=O)C=C3",5.241,4,0,6]
["S5394","Tizoxanide","a8","L1300-23","in 10mM DMSO","FDA",null,null,"Cancer; Infection","HCV Protease","Microbiology","Tizoxanide (Desacetyl-nitazoxanide), a thiazolide anti-infective, is active against anaerobic bacteria, protozoa, and a range of viruses in cell culture models, and is currently in phase II clinical development for treating chronic hepatitis C.",265.25,"173903-47-4",27,101.79,"<1",0,"http://selleckchem.com/products/tizoxanide.html","C10H7N3O4S","free base","Desacetyl-nitazoxanide","OC1=CC=CC=C1C(=O)NC2=NC=C(S2)[N+]([O-])=O",1.388,2,2,3]
["S5395","Phenolphthalein","b8","L1300-23","in 10mM DMSO","DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010",null,"Gastroenterology","Dyes","Others","Phenolphthalein (Phthalimetten) is an acid-base pH indicator.",318.32,"77-09-8",63,197.91,-1,-3.14,"https://www.selleckchem.com/products/phenolphthalein.html","C20H14O4","free base","Phthalimetten","OC1=CC=C(C=C1)C2(OC(=O)C3=C2C=CC=C3)C4=CC=C(O)C=C4",4.006,2,2,2]
["S5397","Chlorhexidine","c8","L1300-23","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,KP Ⅹ,Ph.Int_6th,BP2017,JP17,IP2010","019490,020111,021669,072525,074291,074356,074522,075006,075561,077789","Infection","Anti-infection","Microbiology","Chlorhexidine is a disinfectant and topical anti-infective agent that is active against Gram-positive and Gram-negative organisms, facultative anaerobes, aerobes, and yeasts.",505.45,"55-56-1",100,197.84,-1,-1.98,"https://www.selleckchem.com/products/chlorhexidine.html","C22H30Cl2N10","free base",0,"ClC1=CC=C(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC2=CC=C(Cl)C=C2)C=C1",4.373,0,6,17]
["S5398","Nefazodone hydrochloride","d8","L1300-23","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","075763,076037,076072,076073,076129,076196,076302,076309,076409","Psychotic disorders","5-HT Receptor","Neuronal Signaling","Nefazodone hydrochloride (BMY-13754-1) is the hydrochloride salt form of nefazodone, which is an atypical antidepressant showing antagonistic activity on serotonin reuptake.",506.47,"82752-99-6",22,43.44,-1,-1.97,"https://www.selleckchem.com/products/nefazodone-hydrochloride.html","C25H33Cl2N5O2","free base","BMY-13754-1","Cl.CCC1=NN(CCCN2CCN(CC2)C3=CC(=CC=C3)Cl)C(=O)N1CCOC4=CC=CC=C4",4.797,3,0,10]
["S5399","Chlorprothixene hydrochloride","e8","L1300-23","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,EP9.8,BP2017",null,"Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Chlorprothixene HCl (Minithixen hydrochloride, Truxal hydrochloride, NSC 169899, NSC 56379, NSC 78193) is the  hydrochloride salt form of chlorprothixene, a typical antipsychotic drug of the thioxanthene (tricyclic) class. It exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors.",352.32,"6469-93-8",70,198.68,-1,-2.84,"https://www.selleckchem.com/products/chlorprothixene-hydrochloride.html","C18H19Cl2NS","free base","Minithixen hydrochloride, Truxal hydrochloride, NSC 169899, NSC 56379, NSC 78193","Cl.CN(C)CC\\C=C/1C2=C(SC3=C1C=C(Cl)C=C3)C=CC=C2",5.505,0,0,3]
["S5401","Tegaserod Maleate","f8","L1300-23","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia","021200","Gastroenterology/Neurological Disease","5-HT Receptor","Neuronal Signaling","Tegaserod Maleate(HTF-919) is a hydrogen maleate salt form of tegaserod, which is a 5-HT4 receptor partial agonist and binds with high affinity to 5-HT4 receptors. It has limited affinity for 5-HT1 receptors and no appreciable affinity for other 5-HT receptors, muscarinic, adrenergic, dopaminergic or opiate receptors.",417.46,"189188-57-6",83,198.82,"<1",0,"http://selleckchem.com/products/tegaserod-maleate.html","C16H23N5O.C4H4O4","maleate","HTF-919","CCCCCNC(=N)N/N=C/C1=C[NH]C2=C1C=C(OC)C=C2.OC(=O)\\C=C/C(O)=O",3.17,4,3,11]
["S5402","Dasabuvir (ABT-333)","g8","L1300-23","in 10mM DMSO","FDA,EMA,NDC",null,"206619,208624","Infection","HCV Protease","Proteases","Dasabuvir (ABT-333) is a non-nucleoside inhibitor of NS5B viral RNA-dependent RNA polymerase that inhibits recombinant NS5B polymerases derived from HCV genotype 1a and 1b clinical isolates with IC50 values between 2.2 and 10.7 nM. It is at least 7,000-fold selective for the inhibition of HCV genotype 1 polymerases over human/mammalian polymerases.",493.57,"1132935-63-7",98,198.55,"<1",0,"http://selleckchem.com/products/dasabuvir-abt-333.html","C26H27N3O5S","free base","N/A","COC1=C(C=C(C=C1C2=CC3=CC=C(N[S](C)(=O)=O)C=C3C=C2)N4C=CC(=O)NC4=O)C(C)(C)C",3.492,5,2,6]
["S5403","Ombitasvir (ABT-267)","h8","L1300-23","in 10mM DMSO","FDA,EMA,NDC",null,"207931,206619,208624","Infection","HCV Protease","Proteases","Ombitasvir (ABT-267) is an inhibitor of the HCV non-structural protein 5A with antiviral activity.",894.11,"1258226-87-7",100,111.84,0,0,"http://selleckchem.com/products/ombitasvir-abt-267.html","C50H67N7O8","free base","N/A","COC(=O)NC(C(C)C)C(=O)N1CCCC1C(=O)NC2=CC=C(C=C2)C3CCC(N3C4=CC=C(C=C4)C(C)(C)C)C5=CC=C(NC(=O)C6CCCN6C(=O)C(NC(=O)OC)C(C)C)C=C5",7.103,8,4,16]
["S5404","Paritaprevir (ABT-450)","a9","L1300-23","in 10mM DMSO","FDA,EMA,NDC",null,"207931,206619,208624","Infection","HCV Protease","Proteases","Paritaprevir (ABT-450) is a nonstructural (NS) protein 3/4A protease inhibitor.",765.88,"1216941-48-8",100,130.57,0,0,"http://selleckchem.com/products/paritaprevir-abt-450.html","C40H43N7O7S","free base","N/A","CC1=NC=C(N=C1)C(=O)NC2CCCCC\\C=C/C3CC3(NC(=O)C4CC(CN4C2=O)OC5=NC6=C(C=CC=C6)C7=C5C=CC=C7)C(=O)N[S](=O)(=O)C8CC8",3.104,10,3,7]
["S5405","Propylparaben","b9","L1300-23","in 10mM DMSO",null,"USP41-NF36;BP2015;IP2010",null,"Immunology","Anti-infection","Microbiology","Propylparaben (Propyl 4-hydroxybenzoate, Propyl p-hydroxybenzoate, nipasol), a natural substance found in many plants and some insects, is an antimicrobial, preservative and flavouring agent.",180.2,"94-13-3",36,199.78,"<1",0,"https://www.selleckchem.com/products/propylparaben.html","C10H12O3",0,"Propyl 4-hydroxybenzoate, 4-Hydroxybenzoic acid propyl ester, Propyl p-hydroxybenzoate, nipasol","CCCOC(=O)C1=CC=C(O)C=C1",2.315,2,1,4]
["S5406","Sultamicillin Tosylate","c9","L1300-23","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,CP2005,EP9.2,BP2017",null,"Infection","Bacterial","Microbiology","Sultamicillin Tosylate is the tosylate salt of the double ester of sulbactam plus ampicillin. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would otherwise be resistant.",766.86,"83105-70-8",100,130.4,9,11.74,"http://www.selleckchem.com/products/sultamicillin-tosylate.html","C32H38N4O12S3","Tosylate","N/A","CC1=CC=C(C=C1)[S](O)(=O)=O.CC2(C)SC3CC(=O)N3C2C(=O)OCOC(=O)C4N5C(C(NC(=O)C(N)C6=CC=CC=C6)C5=O)[S](=O)(=O)C4(C)C",1.413,9,2,10]
["S5407","Squalane","d9","L1300-23","in 10mM DMSO","NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017",null,"Cancer","Others","Others","Squalane (Perhydrosqualene, Dodecahydrosqualene) is a naturally occuring lipid in both plants and animals. It is usually used as an emollient and moisturizer in cosmetics manufacturing.",422.81,"111-01-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/squalane.html","C30H62","free base","Perhydrosqualene, Dodecahydrosqualene","CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C",12.831,0,0,21]
["S5410","Chloramphenicol sodium succinate","e9","L1300-23","in 10mM DMSO","FDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,BP2017,Ph.Int_5th,USP39-NF34,JP16,IP2010","062278,062365","Infection","Antibiotics,Bacterial","Microbiology","Chloramphenicol Sodium Succinate is the sodium succinate salt form of chloramphenicol, a nitrobenzene derivate and broad-spectrum antibiotic with antibacterial activity.",445.18,"982-57-0",89,199.92,0,0,"http://selleckchem.com/products/chloramphenicol-sodium-succinate.html","C15H15Cl2N2O8.Na","sodium salt","N/A","[Na+].OC(C(COC(=O)CCC([O-])=O)NC(=O)C(Cl)Cl)C1=CC=C(C=C1)[N+]([O-])=O",-0.225,3,2,11]
["S5411","Sultamicillin","f9","L1300-23","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,CP2005,EP9.1,BP2017",null,"Infection","β-lactamase","Microbiology","Sultamicillin is a newly developed antibiotic in which ampicillin and the β-lactamase inhibitor sulbactam are linked as an ester.",594.66,"76497-13-7",100,168.16,-1,-1.68,"http://selleckchem.com/products/sultamicillin.html","C25H30N4O9S2","free base","N/A","CC1(C)SC2C(NC(=O)C(N)C3=CC=CC=C3)C(=O)N2C1C(=O)OCOC(=O)C4N5C(CC5=O)[S](=O)(=O)C4(C)C",-0.237,9,2,9]
["S5413","Ertugliflozin","g9","L1300-23","in 10mM DMSO","FDA,EMA,NDC",null,"209803","Endocrinology/Metabolic Disease","SGLT","GPCR & G Protein","Ertugliflozin (MK-8835, PF-04971729) is a potent and selective sodium-dependent glucose cotransporter 2 inhibitor with IC50 values of 0.877 nM for h-SGLT2 and 1000-fold higher for h-SGLT1.",436.88,"1210344-57-2",87,199.14,87,199.14,"https://www.selleckchem.com/products/ertugliflozin.html","C22H25ClO7","free base","MK-8835, PF-04971729","CCOC1=CC=C(CC2=C(Cl)C=CC(=C2)C34OCC(CO)(O3)C(O)C(O)C4O)C=C1",2.103,3,4,6]
["S5414","Diflucortolone valerate","h9","L1300-23","in 10mM DMSO","DMF,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17,BP2017",null,"Immunology","Others","Others","Diflucortolone valerate (Afusona, Diflucortolone 21-valerate) is a potent corticosteroid esterified with valeric acid. It helps reduce swelling, itching, and redness.",478.57,"59198-70-8",95,198.51,-1,-2.09,"http://selleckchem.com/products/diflucortolone-valerate.html","C27H36F2O5","free base","Afusona, Diflucortolone 21-valerate","CCCCC(=O)OCC(=O)C1C(C)CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC12C",4.172,4,1,7]
["S5416","Metyrapone","a10","L1300-23","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,JP17,BP2017,","012911","Metabolic Disease","P450 (e.g. CYP17)","Metabolism","Metyrapone (NSC-25265, SU-4885) is an inhibitor of the enzyme steroid 11-beta-monooxygenase (CYP11B1) that inhibits adrenal steroid synthesis.",226.27,"54-36-4",46,203.29,-1,-4.42,"https://www.selleckchem.com/products/metyrapone.html","C14H14N2O","free base","NSC-25265, SU-4885","CC(C)(C1=CC=CN=C1)C(=O)C2=CC=CN=C2",1.847,3,0,3]
["S5418","Parecoxib Sodium","b10","L1300-23","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","COX","Immunology & Inflammation","Parecoxib Sodium (SC-69124) is a water-soluble, injectable sodium salt form of parecoxib, which is a potent and selective inhibitor of cyclo-oxygenase-2 (COX2).",392.4,"198470-85-8",78,198.77,-1,-2.55,"https://www.selleckchem.com/products/parecoxib-sodium.html","C19H17N2NaO4S","free base","SC-69124 Sodium","CCC(=O)N([Na])[S](=O)(=O)C1=CC=C(C=C1)C2=C(C)ON=C2C3=CC=CC=C3",3.36,5,0,5]
["S5419","1,4-Cineole","c10","L1300-23","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","TRP Channel","Transmembrane Transporters","1,4-Cineole (Isocineole) is a widely distributed, natural, oxygenated monoterpene. 1,4-Cineole, present in eucalyptus oil, activates both human TRPM8 and human TRPA1.",154.25,"470-67-7",30,194.49,0,0,"http://selleckchem.com/products/1-4-cineole.html","C10H18O","free base","Isocineole","CC(C)C12CCC(C)(CC1)O2",2.282,1,0,1]
["S5420","Clindamycin alcoholate","d10","L1300-23","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA",null,"063027,063029,063082,063083,065061,065194,065217,065242,065243,065442,091225,207402","Infection/Parasitology","Antibiotics,Bacterial","Microbiology","Clindamycin alcoholate is a crystallizable compound of Clindamycin with alcohol. Clindamycin is a semisynthetic lincosamide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.",479.46,"58207-19-5",95,198.14,0,0,"http://selleckchem.com/products/clindamycin-alcoholate.html","C18H33ClN2O5S.HCl.H2O","hydrochloride, monohydrate","N/A","O.Cl.CCCC1CC(N(C)C1)C(=O)NC(C(C)Cl)C2OC(SC)C(O)C(O)C2O",1.451,2,4,7]
["S5424","Carbaryl","e10","L1300-23","in 10mM DMSO",null,"BP2019;Martindale:The Extra Pharmacopoeia",null,"Others","AChR","Neuronal Signaling","Carbaryl (1-naphthyl methylcarbamate) is a carbamate insecticide and parasiticide and also a potent anticholinesterase agent belonging to the carbamate group of reversible cholinesterase inhibitors.",201.22,"63-25-2",40,198.79,0,0,"http://selleckchem.com/products/carbaryl.html","C12H11NO2","free base","1-naphthyl methylcarbamate","CNC(=O)OC1=C2C=CC=CC2=CC=C1",2.502,2,1,2]
["S5428","Promazine hydrochloride","f10","L1300-23","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","084510,084517","Neurological Disease","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Promazine (Romtiazin, Sinophenin) is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine H1-receptors with antipsychotic effects.",320.88,"53-60-1",64,199.45,0,0,"http://selleckchem.com/products/promazine-hydrochloride.html","C17H20N2S.HCl","hydrochloride","Romtiazin hydrochloride, Sinophenin hydrochloride","Cl.CN(C)CCCN1C2=CC=CC=C2SC3=C1C=CC=C3",4.457,0,0,4]
["S5430","Metoprolol","g10","L1300-23","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,JP17,BP2017,IP2010","076640,076862,076969,077176,077298,077779,078889,090615,090617,202033,203894,204106,204161,207206,207465","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Metoprolol is a cardioselective β1-adrenergic blocking agent with log Kd values of −7.26±0.07, −6.89±0.09, −5.16±0.12 for β1, β2, and β3 adrenoceptors, respectively. It is used for acute myocardial infarction, heart failure, angina pectoris and mild to moderate hypertension.",267.36,"51384-51-1",53,198.23,0,0,"http://selleckchem.com/products/metoprolol.html","C15H25NO3","free base","N/A","COCCC1=CC=C(OCC(O)CNC(C)C)C=C1",1.757,2,2,9]
["S5435","Quinacrine Dihydrochloride Dihydrate","h10","L1300-23","in 10mM DMSO","DMF",null,null,"Infection/Parasitology","Others","Others","Quinacrine (Mepacrine) is a dye of the acridine family that has been widely used as staining agents for DNA and model compounds for intercalators in numerous biophysical studies. It is also an antimalarial drug.",508.91,"6151-30-0",10,19.65,0,0,"http://selleckchem.com/products/quinacrine-dihydrochloride-dihydrate.html","C23H30ClN3O.2HCl.2H2O","dihydrochloride, dihydrate","Mepacrine Dihydrochloride Dihydrate","O.O.Cl.Cl.CCN(CC)CCCC(C)NC1=C2C=C(OC)C=CC2=NC3=CC(=CC=C13)Cl",6.015,2,1,9]
["S5440","Berberine Sulfate","a11","L1300-23","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","Bacterial","Microbiology","Berberine sulfate (Umbellatine), an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria, fungi, and protozoa.",433.43,"633-66-9",20,46.14,0,0,"http://selleckchem.com/products/berberine-sulfate.html","C20H18NO4.HO4S","sulfate","Umbellatine Sulfate","COC1=C(OC)C2=C(C=C1)C=C3C4=C(CC[N+]3=C2)C=C5OCOC5=C4.O[S]([O-])(=O)=O",1.111,4,0,2]
["S5447","Triprolidine Hydrochloride","b11","L1300-23","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017,IP2010","085094,085610,085940,087514,088735","Immunology","Histamine Receptor","Neuronal Signaling","Triprolidine Hydrochloride is the hydrochloride salt form of Triprolidine, which is the first generation histamine H1 antagonist used in allergic rhinitis.",332.87,"6138-79-0",62,186.26,0,0,"http://selleckchem.com/products/triprolidine-hydrochloride.html","C19H22N2.HCl.H2O","hydrochloride, hydrate","N/A","O.Cl.CC1=CC=C(C=C1)\\C(=C/CN2CCCC2)C3=NC=CC=C3",4.249,1,0,4]
["S5450","Sofalcone","c11","L1300-23","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia",null,"Gastroenterology","Others","Others","Sofalcone (SU-88) is an antiulcer drug and a mucosal protective agent, increasing vascular endothelual growth factor via the Nrf2-heme-oxygenase-1 dependent pathway in gastric epithelial cells.",450.52,"64506-49-6",90,199.77,-1,-2.22,"https://www.selleckchem.com/products/sofalcone.html","C27H30O6","free base","SU-88","CC(C)=CCOC1=CC=C(/C=C/C(=O)C2=C(OCC(O)=O)C=C(OCC=C(C)C)C=C2)C=C1",6.065,5,0,12]
["S5453","Hyperoside","e11","L1300-23","in 10mM DMSO",null,"BP2019;EP9.2",null,"Inflammation/Neurological Disease","NF-κB","NF-κB","Hyperoside (Hyperin, Quercetin 3-galactoside), a naturally occuring flavonoid compound, exerts multiple bioactivities, including myocardial protection, anti-redox, and anti-inflammatory activities.Hyperoside can inhibit activation of the NF-κB signaling pathway.",464.38,"482-36-0",92,198.11,1,2.15,"http://selleckchem.com/products/hyperoside.html","C21H20O12","free base","Hyperin, Quercetin 3-galactoside","OCC1OC(OC2=C(OC3=C(C(=CC(=C3)O)O)C2=O)C4=CC(=C(O)C=C4)O)C(O)C(O)C1O",-0.3,4,8,4]
["S5457","Curculigoside","g11","L1300-23","in 10mM DMSO",null,"CP2005",null,"Immunology/Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Curculigoside (Curculigoside A), a diterpenoid triepoxide, is one of the main bioactive phenolic compounds isolated from the rhizome of Curculigo orchioides Gaertn. and has potent antioxidant, anti-osteoporotic, immunomodulatory, and neuroprotective effects.",466.44,"85643-19-2",93,199.38,15,32.16,"http://selleckchem.com/products/curculigoside.html","C22H26O11","free base","Curculigoside A","COC1=C(C(=O)OCC2=CC(=CC=C2OC3OC(CO)C(O)C(O)C3O)O)C(=CC=C1)OC",0.822,6,5,9]
["S5458","Verbascoside","h11","L1300-23","in 10mM DMSO",null,"EP10.4",null,"Others","Immunology & Inflammation related","Immunology & Inflammation","Verbascoside (Acteoside, Kusaginin), a phenylpropanoid glycoside from lemon verbena, has several biological properties such as anti-inflammatory, antimicrobial, antitumor, and antioxidant.",624.59,"61276-17-3",100,160.11,100,160.11,"http://selleckchem.com/products/verbascoside.html","C29H36O15","free base","Acteoside, Kusaginin","CC1OC(OC2C(O)C(OCCC3=CC=C(O)C(=C3)O)OC(CO)C2OC(=O)\\C=C\\C4=CC=C(O)C(=C4)O)C(O)C(O)C1O",0.484,6,9,11]
["S5459","Aucubin","a2","L1300-24","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cardiovascular Disease/Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Aucubin (Rhinanthin), an iridoid glycoside existing in medicinal plants, has been reported to show an anti-inflammatory activity by suppression of TNF-α production in murine macrophages.",346.33,"479-98-1",69,199.23,15,43.31,"http://selleckchem.com/products/aucubin.html","C15H22O9","free base","Rhinanthin","OCC1OC(OC2OC=CC3C(O)C=C(CO)C23)C(O)C(O)C1O",-2.916,3,6,4]
["S5460","Vitexin-2-O-rhaMnoside","b2","L1300-24","in 10mM DMSO",null,"EP10.4",null,"Cardiovascular Disease","Others","Others","Vitexin-2-O-rhamnoside (2''-O-Rhamnosylvitexin, Apigenin-8-C-glucoside) is one of the main components of flavonoid of the leaves of Crataegus pinnatifida Bge. var major N. E. Br. It has many biological and pharmacological activities, such as antioxidation and treating heart disease.",578.52,"64820-99-1",100,172.85,100,172.85,"http://selleckchem.com/products/vitexin-2-o-rhamnoside.html","C27H30O14","free base","2''-O-Rhamnosylvitexin, Apigenin-8-C-glucoside","CC1OC(OC2C(O)C(O)C(CO)OC2C3=C(O)C=C(O)C4=C3OC(=CC4=O)C5=CC=C(O)C=C5)C(O)C(O)C1O",-0.84,5,9,5]
["S5466","Saikosaponin A","c2","L1300-24","in 10mM DMSO",null,"BP2019",null,"Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Saikosaponin A is a triterpene saponin derived from the medicinal plant, Bupleurum chinensis DC. (Umbelliferae). It has a variety of pharmacological benefits, including anti-inﬂammatory, immunomodulatory, and anti-bacterial activities.",780.98,"20736-09-8",100,128.04,"<1",0,"https://www.selleckchem.com/products/saikosaponin-a.html","C42H68O13","free base","N/A","CC1OC(OC2CCC3(C)C(CCC4(C)C3C=CC56OCC7(CCC(C)(C)CC57)C(O)CC46C)C2(C)CO)C(O)C(OC8OC(CO)C(O)C(O)C8O)C1O",1.107,5,8,6]
["S5473","Pivmecillinam hydrochloride","d2","L1300-24","in 10mM DMSO","marketed in the Nordic countries","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,JP17,BP2017",null,"Infection","Antibiotics,Bacterial","Microbiology","Pivmecillinam is a β-lactam antibiotic and a prodrug of mecillinam. It has selective activity against Gram-negative bacteria and is used primarily in the treatment of lower urinary tract infections.",476.03,"32887-03-9",95,199.57,95,199.57,"http://selleckchem.com/products/pivmecillinam-hydrochloride.html","C21H33N3O5S.HCl","hydrochloride","N/A","Cl.CC(C)(C)C(=O)OCOC(=O)C1N2C(SC1(C)C)C(N=CN3CCCCCC3)C2=O",3.161,6,0,8]
["S5476","Rolapitant","e2","L1300-24","in 10mM DMSO","FDC,EMA,NDC",null,null,"Gastroenterology","Neurokinin Receptor","Neuronal Signaling","Rolapitant (SCH-619734) is a selective and competitive antagonist of human substance P/NK1 receptors with antiemetic activity. It has a high affinity for the human NK1 receptor of 0.66 nM and high selectivity over the human NK2 and NK3 subtypes of >1000-fold, as well as preferential affinity for human, guinea pig, gerbil and monkey NK1 receptors over rat, mouse and rabbit.",500.48,"552292-08-7",100,199.81,0,0,"https://www.selleckchem.com/products/rolapitant.html","C25H26F6N2O2",0,"SCH-619734","CC(OCC1(CCC2(CCC(=O)N2)CN1)C3=CC=CC=C3)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F",4.761,2,2,7]
["S5477","Gefarnate","f2","L1300-24","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Inflammation/Ophthalmology","Others","Others","Gefarnate (Geranyl farnesylacetate) is a synthetic compound used for the treatment of gastric ulcers.",400.64,"51-77-4","The physical form of the compound is liquid, which can be dissolved in any proportion.",10,0,0,"https://www.selleckchem.com/products/gefarnate.html","C27H44O2","free base","Geranyl farnesylacetate","CC(C)=CCC/C(C)=C/CC\\C(C)=C\\CCC(=O)OC\\C=C(C)\\CCC=C(C)C",9.003,2,0,15]
["S5478","Dantrolene sodium","g2","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17,BP2017,USP39-NF34","076686,076856,204762,205239","Metabolic Disease","ADC Cytotoxin,Calcium Channel","Transmembrane Transporters","Dantrolene sodium(F 440) acts as a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.",336.23,"14663-23-1",67,199.27,-1,-2.97,"https://www.selleckchem.com/products/s5478-dantrolene-sodium.html","C14H9N4NaO5","free base","F 440","[Na+].[O-]C1=NC(=O)CN1/N=C/C2=CC=C(O2)C3=CC=C(C=C3)[N+]([O-])=O",1.769,4,0,4]
["S5479","Cloperastine hydrochloride","h2","L1300-24","in 10mM DMSO","CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Respiratory Disease","Histamine Receptor","Neuronal Signaling","Cloperastine (HT-11) is a drug with a central antitussive effect, and is also endowed with an antihistaminic activity.",366.32,"14984-68-0",73,199.28,0,0,"http://selleckchem.com/products/cloperastine-hydrochloride.html","C20H24ClNO.HCl","hydrochloride","HT-11 hydrochloride","Cl.ClC1=CC=C(C=C1)C(OCCN2CCCCC2)C3=CC=CC=C3",5.348,1,0,6]
["S5480","Clidinium Bromide","a3","L1300-24","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","010355","Gastroenterology","AChR","Neuronal Signaling","Clidinium Bromide(Ro 2-3773) is an anticholinergic drug.",432.35,"3485-62-9",86,198.91,0,0,"http://selleckchem.com/products/clidinium-bromide.html","C22H26NO3.Br","bromide","Ro 2-3773","[Br-].C[N+]12CCC(CC1)C(C2)OC(=O)C(O)(C3=CC=CC=C3)C4=CC=CC=C4",-0.622,2,0,5]
["S5481","Molindone hydrochloride","b3","L1300-24","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","090453","Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Molindone hydrochloride is the hydrochloride salt form of molindone, a conventional antipsychotic used in the therapy of schizophrenia. It is a dopamine D2/D5 receptor antagonist.",312.83,"15622-65-8",9,28.77,0,0,"http://selleckchem.com/products/molindone-hydrochloride.html","C16H24N2O2.HCl","hydrochloride","N/A","Cl.CCC1=C(C)[NH]C2=C1C(=O)C(CC2)CN3CCOCC3",2.522,2,1,3]
["S5482","Prilocaine hydrochloride","c3","L1300-24","in 10mM DMSO","FDA,NDC,DMF,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,BP2017","079235","Neurological Disease","Others","Others","Prilocaine hydrochloride is the hydrochloride salt form of prilocaine, which is a local anesthetic.",256.77,"1786-81-8",51,198.62,0,0,"https://www.selleckchem.com/products/prilocaine-hydrochloride.html","C13H20N2O.HCl","hydrochloride","N/A","Cl.CCCNC(C)C(=O)NC1=CC=CC=C1C",2.645,1,2,5]
["S5483","Tribenzagan Hydrochloride","d3","L1300-24","in 10mM DMSO","FDA,DMF,NDC",null,"076546,076570,086577,087939,088804,088960,089043,089094,091330","Gastroenterology","Others","Others","Tribenzagan Hydrochloride (Trimethobenzamide) is an orally available, antiemetic agent used in the therapy of nausea and vomiting associated with medications and gastrointestinal, viral and other illnesses.",424.92,"554-92-7",84,197.68,0,0,"http://selleckchem.com/products/trimethobenzamide-hydrochloride.html","C21H28N2O5.HCl","hydrochloride","Trimethobenzamide Hydrochloride","Cl.COC1=C(OC)C(=CC(=C1)C(=O)NCC2=CC=C(OCCN(C)C)C=C2)OC",3.076,5,1,10]
["S5484","Rimantadine Hydrochloride","e3","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","075916,076132,076375","Infection","DNA/RNA Synthesis","DNA Damage/DNA Repair","Rimantadine is an RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza. It works by inhibiting a viral protein called M2, which normally mediates the transport of acid ions across the influenza virion shell.",215.76,"1501-84-4",43,199.3,0,0,"http://selleckchem.com/products/rimantadine-hydrochloride.html","C12H21N.HCl","hydrochloride","N/A","Cl.CC(N)[C]12C[CH]3C[CH]([CH2]C([CH2]3)C1)C2",2.586,0,1,1]
["S5485","Desipramine Hydrochloride","f3","L1300-24","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","071588,071601,071602,071766,071803,071864,071865,071866,071867,072099,072100,072101,072102,072103,072104,074430,204963,205153,207433,208105","Psychotic disorders","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Desipramine hydrochloride (Desmethylimipramine, Norimipramine, EX-4355, G-35020, JB-8181, NSC-114901) is a dibenzazepine-derivative tricyclic antidepressant that acts as a selective norepinephrine reuptake inhibitor. It also shows weak serotonin reuptake inhibitory, α1-blocking, antihistamine, and anticholinergic effects.",302.84,"58-28-6",60,198.12,0,0,"http://selleckchem.com/products/desipramine-hydrochloride.html","C18H22N2.HCl","hydrochloride","Desmethylimipramine, Norimipramine, EX-4355, G-35020, JB-8181, NSC-114901","Cl.CNCCCN1C2=C(CCC3=C1C=CC=C3)C=CC=C2",4.234,0,1,4]
["S5486","Fluorometholone","g3","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,JP17,BP2017","070185,016851,017760,019216,011748","Immunology/Infection/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Fluorometholone (Oxylone) is a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. It is usually used as eye drops in the treatment of allergic and inflammatory conditions of the eye.",376.46,"426-13-1",75,199.22,"<1",0,"http://selleckchem.com/products/fluorometholone.html","C22H29FO4","free base","Oxylone","CC1CC2C3CCC(O)(C(C)=O)C3(C)CC(O)C2(F)C4(C)C=CC(=O)C=C14",2.312,2,1,1]
["S5487","Cefoperazone sodium","h3","L1300-24","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia,CP2005,KP Ⅹ,EP9.1,JP17,BP2017,IP2010","050551,063333","Infection","Antibiotics,Bacterial","Microbiology","Cefoperazone Sodium(CP 52640-2) is the sodium salt form of cefoperazone, which is a semi-synthetic, broad-spectrum, beta-lactamase resistant antibiotic with bactericidal activity.",667.65,"62893-20-3",100,149.78,-1,-1.5,"https://www.selleckchem.com/products/cefoperazone-sodium.html","C25H26N9NaO8S2","free base","CP 52640-2","[Na+].CCN1CCN(C(=O)NC(C(=O)NC2C3SCC(=C(N3C2=O)C([O-])=O)CSC4=NN=N[N]4C)C5=CC=C(O)C=C5)C(=O)C1=O",-2.266,8,3,9]
["S5488","Fluorescein","a4","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,Ph.Int_6th,JP17,BP2017,IP2010","021980","Diagnosis","Dyes","Others","Fluorescein (Solvent Yellow 94, Resorcinolphthalein, Yellow fluorescein) is a manufactured organic compound and dye.",332.31,"2321-07-5",67,201.62,-1,-3.01,"https://www.selleckchem.com/products/fluorescein.html","C20H12O5","free base","Solvent Yellow 94, Resorcinolphthalein, Yellow fluorescein","OC1=CC2=C(C=C1)C3(OC(=O)C4=C3C=CC=C4)C5=C(O2)C=C(O)C=C5",3.737,3,2,0]
["S5490","Disopyramide","b4","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,JP17,BP2017,IP2010","070101,070102,070138,070139,070173,070186,070187,070240,070241,070351,070352,070470,070471,070940,070941,071190,071191,071200","Cardiovascular Disease","Sodium Channel","Transmembrane Transporters","Disopyramide is a class IA antiarrhythmic drug which acts via blockade of sodium channels depressing phase 0 of the action potential. Disopyramide possesses significant negative inotropic, anticholinergic effects and enhances AV nodal conduction.",339.47,"3737-09-5",67,197.37,0,0,"http://selleckchem.com/products/disopyramide.html","C21H29N3O",0,"N/A","CC(C)N(CCC(C(N)=O)(C1=CC=CC=C1)C2=NC=CC=C2)C(C)C",3.417,2,1,8]
["S5491","Lomefloxacin","c4","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia","020013","Infection","Antibiotics,Bacterial","Microbiology","Lomefloxacin(SC47111A) is a fluoroquinolone antibiotic used to treat bacterial infections.",351.35,"98079-51-7",7,19.92,-1,-2.85,"https://www.selleckchem.com/products/lomefloxacin.html","C17H19F2N3O3","free base","SC47111A","CCN1C=C(C(O)=O)C(=O)C2=C1C(=C(N3CCNC(C)C3)C(=C2)F)F",-0.828,2,1,3]
["S5492","Econazole","d4","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017,IP2010","076005,076075,076479,076574,210364","Immunology/Infection","Bacterial","Microbiology","Econazole is a broad spectrum antimycotic with some action against Gram positive bacteria.",381.68,"27220-47-9",76,199.12,0,0,"http://selleckchem.com/products/econazole.html","C18H15Cl3N2O","free base","N/A","ClC1=CC=C(COC(C[N]2C=CN=C2)C3=C(Cl)C=C(Cl)C=C3)C=C1",4.981,2,0,6]
["S5493","Atropine sulfate","e4","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,EP9.3,Ph.Int_6th,JP17,BP2017","020056,206289,209260","Neurological Disease/Ophthalmology","AChR","Neuronal Signaling","Atropine Sulfate (Sulfatropinol, Atropette, Tropintran) is the sulfate salt of atropine, which is a natural alkaloid anticholinergic agent and has potent antimuscarinic effects.",676.82,"55-48-1",18,26.59,0,0,"https://www.selleckchem.com/products/atropine-sulfate.html","C34H46N2O6.H2SO4","sulfate","Sulfatropinol, Atropette, Tropintran","CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN4C5CCC4CC(C5)OC(=O)C(CO)C6=CC=CC=C6.O[S](O)(=O)=O",2.835,4,2,10]
["S5494","Salbutamol","f4","L1300-24","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,KP Ⅹ,EP9.2,Ph.Int_6th,JP17,BP2017,IP2010",null,"Immunology/Respiratory Disease","Adrenergic Receptor","Neuronal Signaling","Salbutamol (Albuterol) is a short-acting, selective beta2-adrenergic receptor agonist used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases.",239.31,"18559-94-9",47,196.4,0,0,"https://www.selleckchem.com/products/salbutamol.html","C13H21NO3","free base","Albuterol","CC(C)(C)NCC(O)C1=CC=C(O)C(=C1)CO",0.941,0,4,5]
["S5497","Iopanoic acid","g4","L1300-24","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017,Ph.Int_5th,USP39-NF34","008032","Diagnosis","Others","Others","Iopanoic acid (Acidum iopanoicum, Iodopanoic acid) is an iodine-containing radiocontrast medium used in cholecystography.",570.93,"96-83-3",100,175.15,0,0,"http://selleckchem.com/products/iopanoic-acid.html","C11H12I3NO2","free base","Acidum iopanoicum, Iodopanoic acid","CCC(CC1=C(I)C=C(I)C(=C1I)N)C(O)=O",3.857,1,1,4]
["S5498","Betahistine mesylate","h4","L1300-24","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,IP2010,BP2017",null,"Neurological Disease","Histamine Receptor","Neuronal Signaling","Betahistine mesylate is the mesylate salt form of Betahistine, a histamine analog and H3 receptor agonist that serves as a vasodilator.",328.41,"54856-23-4",65,197.92,0,0,"http://selleckchem.com/products/betahistine-mesylate.html","C8H12N2.2CH4O3S","dimethanesulfonate","N/A","CNCCC1=CC=CC=N1.C[S](O)(=O)=O.C[S](O)(=O)=O",-0.148,1,1,3]
["S5500","Amodiaquine hydrochloride","a5","L1300-24","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,Ph.Int_6th,IP2010","006441","Infection/Parasitology","Immunology & Inflammation related","Immunology & Inflammation","Amodiaquine Hydrochloride is the hydrochloride salt of amodiaquine, an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties.",428.78,"69-44-3",56,130.6,0,0,"https://www.selleckchem.com/products/amodiaquine-hydrochloride.html","C20H22ClN3O.2HCl","dihydrochloride","N/A","Cl.Cl.CCN(CC)CC1=CC(=CC=C1O)NC2=C3C=CC(=CC3=NC=C2)Cl",5.523,1,2,6]
["S5501","Hydrocortisone acetate","b5","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,Ph.Int_5th,USP39-NF34,BP2015,JP16,IP2010","009637,040259,080419,080828,083128,083739,083759,085214,085981,086050,086052,089914","Endocrinology/Gastrointestinal Disease/Inflammation/Infection/Hematology/Metabolic Disease","Immunology & Inflammation related","Immunology & Inflammation","Hydrocortisone Acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties.",404.5,"50-03-3",80,197.78,0,0,"https://www.selleckchem.com/products/hydrocortisone-acetate.html","C23H32O6","free base","Cortisol 21-acetate","CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3C(O)CC12C",1.662,4,1,4]
["S5502","Ilaprazole sodium","c5","L1300-24","in 10mM DMSO","CFDA",null,null,"Gastrointestinal Disease","ATPase,Proton Pump","Transmembrane Transporters","Ilaprazole (IY-81149) sodium is the sodium salt form of ilaprazole, which is a proton pump inhibitor. Ilaprazole sodium irreversibly inhibits H(+)/K(+)-ATPase in a dose-dependent manner with IC50 of 6 μM in rabbit parietal cell preparation.",388.42,"172152-50-0",78,200.81,-1,0,"http://www.selleckchem.com/products/iiaprazole-sodium.html","C19H17N4NaO2S","Sodium Salt","IY-81149 sodium","COC1=C(C)C(=NC=C1)C[S](=O)C2=NC3=C(C=CC(=C3)[N]4C=CC=C4)[N]2[Na]",3.414,4,0,5]
["S5503","O-Acetyl-L-carnitine hydrochloride","d5","L1300-24","in 10mM DMSO","Marketed in Italy",null,null,"Metabolism","Others","Others","O-Acetyl-L-carnitine (Acetyl-L-carnitine, O-acetyl-L-carnitine, O-Acetylcarnitine) can be synthesis or is naturally found in healthy humans. It could help transport fatty acids into the mitochondrial matrix where fatty acid metabolism occurs.",239.7,"5080-50-2",48,200.25,-1,-4.17,"https://www.selleckchem.com/products/o-acetyl-l-carnitine-hydrochloride.html","C9H18ClNO4",0,"Acetyl-L-carnitine, O-acetyl-L-carnitine, O-Acetylcarnitine","[Cl-].CC(=O)OC(CC(O)=O)C[N+](C)(C)C",-4.111,3,0,6]
["S5504","Ropivacaine","e5","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","078601,090194,090318,203955,204636,205612,206166,207636,210102","Neurological Disease","Others","Others","Ropivacaine is a member of the amino amide class of local anesthetics.",274.4,"84057-95-4",23,83.82,"<1",0,"https://www.selleckchem.com/products/ropivacaine.html","C17H26N2O",0,0,"CCCN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",3.853,1,1,4]
["S5505","2’-deoxyuridine","f5","L1300-24","in 10mM DMSO","DMF",null,null,"Others","DNA/RNA Synthesis","DNA Damage/DNA Repair","2'-deoxyuridine (dU, 2'-dU) is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms.",228.2,"951-78-0",45,197.19,-1,-4.38,"https://www.selleckchem.com/products/2-deoxyuridine.html","C9H12N2O5",0,"dU, 2'-dU","OCC1OC(CC1O)N2C=CC(=O)NC2=O",-1.685,3,3,2]
["S5507","Trimebutine maleate","g5","L1300-24","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,EP9.3,KP Ⅹ,JP17,BP2017",null,"Gastroenterology","Opioid Receptor","Neuronal Signaling","Trimebutine maleate is the maleate salt form of trimebutine, which is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects.",503.54,"34140-59-5",100,198.59,-1,-1.99,"https://www.selleckchem.com/products/trimebutine-maleate.html","C26H33NO9",0,"3, 4, 5-Trimethoxybenzoic Acid 2-(Dimethylamino)-2-phenylbutyl Ester Maleate Salt;","CCC(COC(=O)C1=CC(=C(OC)C(=C1)OC)OC)(N(C)C)C2=CC=CC=C2.OC(=O)\\C=C/C(O)=O",1.12,7,0,12]
["S5515","Penicillin G Procaine","h5","L1300-24","in 10mM DMSO","FDA,NDC,DMF","USP42-NF37,EP9.0","060099,060101,060800,062029","Infection/Inflammation","Antibiotics,Bacterial","Microbiology","Procaine benzylpenicillin (Procaine benzylpenicillin,PGP), also known as Procaine benzylpenicillin, is an antibiotic useful for the treatment of a number of bacterial infections.",588.72,"6130-64-9",100,169.86,0,0,"http://selleckchem.com/products/penicillin-g-procaine.html","C16H18N2O4S.C13H20N2O2.H2O","salt","Procaine benzylpenicillin,PGP","O.CCN(CC)CCOC(=O)C1=CC=C(N)C=C1.CC2(C)SC3C(NC(=O)CC4=CC=CC=C4)C(=O)N3C2C(O)=O",-0.343,5,2,11]
["S5527","Salmeterol","a6","L1300-24","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","020236,020692","Immunology/Inflammation/Respiratory Disease","Adrenergic Receptor","Neuronal Signaling","Salmeterol (Astmerole, GR-33343X, SN408D) is a long-acting beta2-adrenergic receptor agonist with Ki value of 1.5 nM for WT β2AR and shows very high selectivity for the WT β2AR(β1Ki/β2Ki ratio of approximately 1500).",415.57,"89365-50-4",83,199.73,"<1",0,"http://selleckchem.com/products/salmeterol.html","C25H37NO4","free base","Astmerole, GR-33343X, SN408D","OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC2=CC=CC=C2",4.251,1,4,16]
["S5528","Acetophenone","b6","L1300-24","in 10mM DMSO","DMF","USP42-NF37",null,"Others","Others","Others","Acetophenone (Methyl phenyl ketone, Phenylethanone) is an organic compound used as fragrances and a raw material for the synthesis of some pharmaceuticals.",120.15,"98-86-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/acetophenone.html","C8H8O","free base","Methyl phenyl ketone, Phenylethanone","CC(=O)C1=CC=CC=C1",1.569,1,0,1]
["S5530","Geraniol","c6","L1300-24","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Immunology/Inflammation","Others","Others","Geraniol is a terpene alcohol occurring in the essential oils of several aromatic plants used in the flavour and fragrance industries. It also exhibits insecticidal and repellent properties and used as a natural pest control agent exhibiting low toxicity.,",154.25,"106-24-1","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/geraniol.html","C10H18O","free base","N/A","CC(C)=CCC\\C(C)=C\\CO",2.934,0,1,4]
["S5531","Doripenem","d6","L1300-24","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","022106","Infection","Antibiotics","Microbiology","Doripenem(S 4661) is a new parenteral carbapenem antibiotic with broad-spectrum activity against gram-negative and gram-positive pathogens.",420.5,"148016-81-3",60,142.69,-1,-2.38,"https://www.selleckchem.com/products/doripenem.html","C15H24N4O6S2","free base","S 4661","CC(O)C1C2C(C)C(=C(N2C1=O)C(O)=O)SC3CNC(CN[S](N)(=O)=O)C3",-5.339,4,4,7]
["S5532","Erythromycin estolate","e6","L1300-24","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,BP2017","062087,062162,062169,062237,062353,062362,062409","Infection","Bacterial","Microbiology","Erythromycin (Lubomycine B), a naturally occurring macrolide, is derived from Streptomyces erythrus. It inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.",1056.39,"3521-62-8",100,94.66,-1,-0.95,"https://www.selleckchem.com/products/erythromycin-estolate.html","C52H97NO18S","free base","Lubomycine B","CCCCCCCCCCCCO[S](O)(=O)=O.CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3OC(=O)CC)N(C)C)C(C)(O)CC(C)C(=O)C(C)C(O)C1(C)O",7.248,11,2,22]
["S5535","Moxifloxacin","f6","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8,BP2017","076938,077437,078073,090080,200160,202525,202632,202867,202916,204079,204635,205348,205572,206242,206295,207285,208682,209469","Infection/Inflammation","Antibiotics,Bacterial","Microbiology","Moxifloxacin is an antibiotic used to treat a number of bacterial infections, active against Mycobacterium tuberculosis in vitro.",401.43,"151096-09-2",24,59.79,-1,-2.49,"https://www.selleckchem.com/products/moxifloxacin.html","C21H24FN3O4","free base","BAY12-8039","COC1=C2N(C=C(C(O)=O)C(=O)C2=CC(=C1N3CC4CCCNC4C3)F)C5CC5",-0.702,3,1,4]
["S5537","Tizanidine","g6","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017,IP2010","076280,076281,076282,076283,076284,076286,076321,076347,076354,076371,076416,076533,078868,091283,091502,207170,207199,208187,208622,209605,210021,210267,211798,212196","Neurological Disease","Adrenergic Receptor","Neuronal Signaling","Tizanidine is an imidazoline derivative and a centrally acting α2 adrenergic agonist used as a muscle relaxant for therapy of acute muscle spasms and chronic spasticity.",253.71,"51322-75-9",50,197.07,15,59.12,"http://selleckchem.com/products/tizanidine.html","C9H8ClN5S",0,"N/A","ClC1=C(NC2=NCCN2)C3=NSN=C3C=C1",1.817,3,2,2]
["S5538","Tropisetron","h6","L1300-24","in 10mM DMSO","CFDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017",null,"Gastroenterology","5-HT Receptor,AChR","Neuronal Signaling","Tropisetron (ICS 205-930) is a 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.",284.35,"89565-68-4",10,35.17,56,196.94,"http://selleckchem.com/products/tropisetron.html","C17H20N2O2","free base","ICS 205-930","CN1C2CCC1CC(C2)OC(=O)C3=C[NH]C4=C3C=CC=C4",2.608,2,1,3]
["S5539","Olprinone","a7","L1300-24","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","PDE","Metabolism","Olprinone is a phosphodiesterase III (PDE3) inhibitor with IC50 values of 0.35 mM, 150 mM and 100 mM for human cardiac PDE III, PDE I and PDE II, respectively.",250.26,"106730-54-5",50,199.8,-1,-4,"https://www.selleckchem.com/products/olprinone.html","C14H10N4O","free base",0,"CC1=C(C=C(C#N)C(=O)N1)C2=C[N]3C=CN=C3C=C2",0.248,2,1,1]
["S5540","Landiolol hydrochloride","b7","L1300-24","in 10mM DMSO","PMDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Landiolol hydrochloride (ONO-1101) is the hydrochloride salt form of Landiolol, which is an ultra-short-acting β1 selective adrenoceptor antagonist.",546.05,"144481-98-1",100,183.13,100,183.13,"https://www.selleckchem.com/products/landiolol-hydrochloride.html","C25H39N3O8.HCl","hydrochloride","ONO-1101 hydrochloride","Cl.CC1(C)OCC(COC(=O)CCC2=CC=C(OCC(O)CNCCNC(=O)N3CCOCC3)C=C2)O1",0.4,7,3,14]
["S5541","Dimetridazole","c7","L1300-24","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,BP2017,IP2010",null,"Infection","Antineoplastic and Immunosuppressive Antibiotics,Fungal","Microbiology","Dimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds.",141.13,"551-92-8",28,198.4,0,0,"http://selleckchem.com/products/dimetridazole.html","C5H7N3O2","free base","N/A","C[N]1C(=NC=C1[N+]([O-])=O)C",0.202,1,0,1]
["S5543","1, 10-Phenanthroline monohydrate","d7","L1300-24","in 10mM DMSO",null,"IP2010;USP42-NF37",null,"Infection","MMP","Proteases","1,10-Phenanthroline is a classic chelating bidentate ligand for transition metal ions that has played an important role in the development of coordination chemistry. It is an inhibitor of metallopeptidases.",198.22,"5144-89-8",39,196.75,0,0,"http://selleckchem.com/products/1-10-phenanthroline-monohydrate.html","C12H8N2.H2O","hydrate","Phenanthroline monohydrate","O.C1=CC2=C(N=C1)C3=C(C=CC=N3)C=C2",1.995,2,0,0]
["S5544","D-Ribose","e7","L1300-24","in 10mM DMSO","DMF,NDC",null,null,"Cancer/Infection","Others","Others","D-ribose is a naturally occurring sugar involved in producing energy in the body and is also the structural basis of DNA and RNA.",150.13,"50-69-1",30,199.83,0,0,"http://selleckchem.com/products/d-ribose.html","C5H10O5","free base","N/A","OCC(O)C(O)C(O)C=O",-2.28,1,4,4]
["S5546","Sulfacetamide","f7","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,Ph.Int_6th,BP2017","040066,040215,040216,077015,078649,078668,080029,088947,089068,089560","Infection","Bacterial","Microbiology","Sulfacetamide (Acetosulfamine) is a synthetic sulfanylacetamide derivative with bacteriostatic activity. It is an anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.",214.24,"144-80-9",43,200.71,-1,-4.67,"https://www.selleckchem.com/products/sulfacetamide.html","C8H10N2O3S","free base","Acetosulfamine","CC(=O)N[S](=O)(=O)C1=CC=C(N)C=C1",-0.222,3,2,2]
["S5547","Hydroxylammonium chloride","g7","L1300-24","in 10mM DMSO",null,"IP2010",null,"Others","Others","Others","Hydroxylammonium chloride (Hydroxylamine hydrochloride) is the hydrochloric acid salt of hydroxylamine, which is a biological intermediate in the nitrification and in the anammox.",69.46,"5470-11-1","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/hydroxylammonium-chloride.html","HCl.H3NO","chloride","Hydroxylamine hydrochloride","Cl.NO",-0.305,0,1,0]
["S5550","Ethyl gallate","h7","L1300-24","in 10mM DMSO",null,"BP2019;Martindale:The Extra Pharmacopoeia",null,"Others","Bcl-2,Caspase","Apoptosis","Ethyl gallat (Phyllemblin, gallic acid ethyl ester), which could be found naturally in a variety of plant sources, is a food additive with antimicrobial activity. Ethyl gallat activates the death receptor-dependent pathway of apoptosis by enhancing the expression of caspases-8, -9, and -3 and the Bcl-2 interacting domain (Bid).",198.17,"831-61-8",39,196.8,0,0,"https://www.selleckchem.com/products/ethyl-gallate.html","C9H10O5",0,"Phyllemblin, gallic acid ethyl ester","CCOC(=O)C1=CC(=C(O)C(=C1)O)O",1.308,2,3,3]
["S5552","Amenamevir","a8","L1300-24","in 10mM DMSO","PMDA",null,null,"Infection","DNA/RNA Synthesis","DNA Damage/DNA Repair","Amenamevir (ASP2151) is a potent helicase-primase inhibitor and a novel class of antiviral agent.",482.55,"841301-32-4","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/amenamevir.html","C24H26N4O5S","free base","ASP2151","CC1=C(N(CC(=O)NC2=CC=C(C=C2)C3=NOC=N3)C(=O)C4CC[S](=O)(=O)CC4)C(=CC=C1)C",2.24,7,1,6]
["S5553","Kasugamycin hydrochloride","b8","L1300-24","in 10mM DMSO","CFDA",null,null,"Infection","Antineoplastic and Immunosuppressive Antibiotics,Fungal,Selection Antibiotics for Transfected Cell","Microbiology","Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.",415.82,"19408-46-9","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/kasugamycin-hydrochloride.html","C14H25N3O9.HCl","hydrochloride","N/A","Cl.CC1OC(OC2C(O)C(O)C(O)C(O)C2O)C(N)CC1NC(=N)C(O)=O",-6.175,3,7,5]
["S5554","Lanatoside C","c8","L1300-24","in 10mM DMSO",null,"BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Akt,Antiviral,Apoptosis related,Autophagy,JAK,mTOR,PI3K,STAT,Wnt/beta-catenin","Immunology & Inflammation","Lanatoside C is a cardiac glycoside with antiviral and anti-tumor activity. Lanatoside C induces G2/M cell cycle arrest and induces autophagy and apoptosis via attenuating MAPK, Wnt, JAK-STAT, and PI3K/AKT/mTOR signaling pathways.",985.12,"17575-22-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/lanatoside-c.html","C49H76O20","free base","N/A","CC1OC(CC(O)C1OC2CC(O)C(OC3CC(OC(C)=O)C(OC4OC(CO)C(O)C(O)C4O)C(C)O3)C(C)O2)OC5CCC6(C)C(CCC7C6CC(O)C8(C)C(CCC78O)C9=CC(=O)OC9)C5",0.631,12,7,12]
["S5555","Pamabrom","d8","L1300-24","in 10mM DMSO","DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ",null,"Metabolic Disease","Others","Others","Pamabrom is a diuretic agent.",348.2,"606-04-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/pamabrom.html","C7H7BrN4O2.C4H11NO","salt","N/A","CN1C(=O)N(C)C2=C([NH]C(=N2)Br)C1=O.CC(C)(N)CO",0.074,3,3,1]
["S5556","(-)-Sparteine Sulfate","e8","L1300-24","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Sodium Channel","Transmembrane Transporters","Sparteine Sulfate, a quinolizidine alkaloid, is the sulfate form of sparteini, which is a sodium channel blocker used as an oxytocic and an anti-arrhythmia agent.",422.54,"6160-12-9","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/sparteini-sulfas.html","C15H26N2.H2SO4.5H2O","sulfate pentahydrate","N/A","O.O.O.O.O.O[S](O)(=O)=O.C1CCN2CC3CC(CN4CCCCC34)C2C1",0.72,0,0,0]
["S5558","D-Pantothenate Sodium","f8","L1300-24","in 10mM DMSO","NDC",null,null,"Cardiovascular Disease/Metabolic Disease/Neurological Disease","Vitamin","Metabolism","D-Pantothenate Sodium, the sodium salt of D-pantothenate, is a derivative of vitamin B5 which is an an essential nutrient and plays important roles in the oxidation of fats and carbohydrates and certain amino acids.",241.22,"867-81-2",6,24.87,0,0,"http://selleckchem.com/products/d-pantothenate-sodium.html","C9H16NO5.Na","sodium salt","N/A","[Na+].CC(C)(CO)C(O)C(=O)NCCC([O-])=O",-2.533,1,3,6]
["S5559","(+/-)-tetrahydropalmatine","g8","L1300-24","in 10mM DMSO","CFDA",null,null,"Neurological Disease","Dopamine Receptor","Neuronal Signaling","(+/-)-tetrahydropalmatine, a plant alkaloid used as an ingredient in dietary supplement products, is a potent and selective D1 receptor antagonist.",355.43,"2934-97-6",16,45.02,"<1",0,"http://selleckchem.com/products/tetrahydropalmatine.html","C21H25NO4","free base","Rotundine","COC1=C(OC)C=C2C3CC4=CC=C(OC)C(=C4CN3CCC2=C1)OC",3.599,4,0,4]
["S5560","Midecamycin","h8","L1300-24","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Infection","Antibiotics,Bacterial","Microbiology","Midecamycin (Espinomycin A, Medecamycin A1, Platenomycin B1, Rubimycin, Turimycin P3) is a naturally occuring macrolide antibiotic that acts by inhibiting bacterial protein synthesis.",813.97,"35457-80-8",100,122.85,"<1",0,"http://selleckchem.com/products/midecamycin.html","C41H67NO15","free base","Espinomycin A, Medecamycin A1, Platenomycin B1, Rubimycin, Turimycin P3","CCC(=O)OC1CC(=O)OC(C)C/C=C/C=C/C(O)C(C)CC(CC=O)C(OC2OC(C)C(OC3CC(C)(O)C(OC(=O)CC)C(C)O3)C(C2O)N(C)C)C1OC",2.916,12,2,14]
["S5561","Ethacrynic Acid","a9","L1300-24","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37,IP2010","205609,205709,207262,208501,208805","Cardiovascular Disease/Metabolic Disease","Others","NF-κB","Ethacrynic Acid is a loop or high ceiling diuretic used for the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.",303.14,"58-54-8",61,201.23,-1,0,"http://www.selleckchem.com/products/ethacrynic-acid.html","C13H12Cl2O4","Free Base","N/A","CCC(=C)C(=O)C1=C(Cl)C(=C(OCC(O)=O)C=C1)Cl",3.963,3,0,6]
["S5562","2-Hydroxybenzyl alcohol","b9","L1300-24","in 10mM DMSO",null,"USP42-NF37",null,"Others","Others","Others","2-Hydroxybenzyl alcohol (Salicyl alcohol, Salicain, Diathesin, Saligenin, Saligenol, o-Methylolphenol, α,2-Toluenediol), which can be found in a number of food items such as red huckleberry, rye, jerusalem artichoke, and ceylon cinnamon, is precursor of salicylic acid and is formed from salicin by enzymatic hydrolysis by Salicyl-alcohol beta-D-glucosyltransferase or by acid hydrolysis.",124.14,"90-01-7",24,193.33,0,0,"http://selleckchem.com/products/2-hydroxybenzyl-alcohol.html","C7H8O2","free base","Salicain, Diathesin, Saligenin, Saligenol, o-Methylolphenol, α,2-Toluenediol","OCC1=CC=CC=C1O",0.983,0,2,1]
["S5563","Thioridazine hydrochloride","c9","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","040125,040126,040187,040213,087264,087766,088004,088131,088132,088133,088134,088135,088136,088137,088194,088227,088229,088258,088270,088271,088272,088273,088284,088296,088307,088308,088322,088323,088332,088333,088334,088335,088336,088345,088351,088352,088370,088375,088379,088381,088410,088412,088456,088461,088476,088477,088478,088479,088480,088493,088561,088562,088563,088564,088567,088658,088659,088660,088661,088663,088664,088665,088736,088737,088738,088755,088869,088872,089048,089103,089104,089105,089602,089603,089764,089765,089953","Psychotic disorders","5-HT Receptor","Neuronal Signaling","Thioridazine (Aldazine, Mellaril) is a potent antianxiety and antipsychotic agent.",407.04,"130-61-0",81,199,0,0,"http://selleckchem.com/products/thioridazine-hydrochloride.html","C21H26N2S2.HCl","hydrochloride","Aldazine, Mellaril","Cl.CSC1=CC2=C(SC3=CC=CC=C3N2CCC4CCCCN4C)C=C1",5.945,0,0,4]
["S5564","Xylazine","d9","L1300-24","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017",null,"Neurological Disease","Adrenergic Receptor","Neuronal Signaling","Xylazine is a partial alpha-2 adrenergic agonist that is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals.",220.33,"7361-61-7",44,199.7,-1,-4.54,"https://www.selleckchem.com/products/xylazine.html","C12H16N2S","free base",0,"CC1=C(NC2=NCCCS2)C(=CC=C1)C",3.265,1,1,2]
["S5565","Triflupromazine hydrochloride","e9","L1300-24","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,IP2010","011123,011325,011491","Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Triflupromazine hydrochloride (Fluopromazine) is an antipsychotic medication of the phenothiazine class.",388.88,"1098-60-8",78,200.58,0,0,"https://www.selleckchem.com/products/triflupromazine-hydrochloride.html","C18H20ClF3N2S",0,"Fluopromazine hydrochloride","Cl.CN(C)CCCN1C2=C(SC3=CC=C(C=C13)C(F)(F)F)C=CC=C2",5.399,0,0,5]
["S5566","Dapagliflozin propanediol monohydrate","f9","L1300-24","in 10mM DMSO","DMF",null,null,"Endocrinology/Metabolic Disease","SGLT","GPCR & G Protein","Dapagliflozin propanediol belongs to the class of orally administered antidiabetic agents designated as sodiumglucose cotransporter 2 (SGLT2) inhibitors.",502.98,"960404-48-2",100,198.82,"<1",0,"http://selleckchem.com/products/dapagliflozin-propanediol-monohydrate.html","C21H25ClO6.C3H8O2.H2O","monohydrate","N/A","O.CCOC1=CC=C(CC2=C(Cl)C=CC(=C2)C3OC(CO)C(O)C(O)C3O)C=C1.CC(O)CO",1.682,2,6,7]
["S5567","Trimethadione","g9","L1300-24","in 10mM DMSO","FDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,EP9.2,Ph.Int_6th,JP17,BP2017","005856","Neurological Disease","Calcium Channel","Transmembrane Transporters","Trimethadione is an oxazolidinedione anticonvulsant and often used to treat epileptic conditions that are resistant to other treatments.",143.14,"127-48-0",28,195.61,0,0,"http://selleckchem.com/products/trimethadione.html","C6H9NO3",0,"N/A","CN1C(=O)OC(C)(C)C1=O",0.488,3,0,0]
["S5568","Tocofersolan","h9","L1300-24","in 10mM DMSO","EMA",null,null,"Others","Vitamin","Metabolism","Tocofersolan (Tocophersolan) is a synthetic water-soluble version of vitamin E that is used in treatment of vitamin E deficiency.",574.83,"9002-96-4",100,173.96,-1,-1.74,"https://www.selleckchem.com/products/tocofersolan.html","(C2H4O)nC33H54O5","free base","Tocophersolan","CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=C(C)C(=C(C)C(=C2O1)C)OC(=O)CCC(=O)OCCO",10.716,5,1,20]
["S5573","Tilmicosin phosphate","a10","L1300-24","in 10mM DMSO",null,"USP42-NF37;Martindale:The Extra Pharmacopoeia",null,"Infection","Antibiotics","Microbiology","Tilmicosin phosphate is a macrolide antibiotic that is used to treat cattle for pathogens that cause Bovine Respiratory Disease.",967.13,"137330-13-3",100,103.4,0,0,"http://selleckchem.com/products/tilmicosin-phosphate.html","C46H80N2O13.H3O4P","phosphate","N/A","CCC1OC(=O)CC(O)C(C)C(OC2OC(C)C(O)C(C2O)N(C)C)C(CCN3CC(C)CC(C)C3)CC(C)C(=O)\\C=C\\C(=C\\C1COC4OC(C)C(O)C(OC)C4OC)C.O[P](O)(O)=O",3.392,9,4,12]
["S5580","Arabic gum","b10","L1300-24","in 10mM DMSO","NDC",null,null,"Immunology","Others","Others","Arabic gum, derived from exudates of Acacia senegal or Acacia seyal trees, is a complex polysaccharide indigestible to both humans and animals and considered as a safe dietary fiber.",0,"9000-01-5","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/arabic-gum.html",0,0,"N/A",0,0,0,0,0]
["S5581","Olmesartan","c10","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA",null,"078276","Cardiovascular Disease","Angiotensin Receptor","GPCR & G Protein","Olmesartan (RNH-6270) is an an angiotensin 2 receptor antagonist with antihypertensive activity.",446.5,"144689-24-7",89,199.33,-1,-2.24,"https://www.selleckchem.com/products/olmesartan.html","C24H26N6O3","free base","RNH-6270","CCCC1=NC(=C([N]1CC2=CC=C(C=C2)C3=C(C=CC=C3)C4=NN=N[NH]4)C(O)=O)C(C)(C)O",3.766,5,1,8]
["S5582","Cytarabine hydrochloride","d10","L1300-24","in 10mM DMSO","CFDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Cancer/Hematology","DNA/RNA Synthesis","DNA Damage/DNA Repair","Cytarabine is a pyrimidine nucleoside analog that is used mainly in the treatment of leukemia. It is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA.",279.68,"69-74-9",55,196.65,0,0,"http://selleckchem.com/products/cytarabine-hydrochloride.html","C9H13N3O5.HCl","hydrochloride","N/A","Cl.NC1=NC(=O)N(C=C1)C2OC(CO)C(O)C2O",-2.014,3,4,2]
["S5583","Cinnamyl acetate","e10","L1300-24","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Others","Others","Cinnamyl acetate (3-Phenylallyl acetate) is a naturally occuring compound used as a flavouring agent.",176.21,"103-54-8",35,198.63,0,0,"http://selleckchem.com/products/cinnamyl-acetate.html","C11H12O2","free base","3-Phenylallyl acetate","CC(=O)OC/C=C/C1=CC=CC=C1",2.072,2,0,4]
["S5585","Citronellal","f10","L1300-24","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Others","Others","Citronellal (Rhodinal, 2,3-Dihydrocitral), a monoterpenoid found in oil of citronella, lemon, and lemon grass, has insect repellent properties and is used in perfumes.",154.25,"106-23-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"https://www.selleckchem.com/products/citronellal-rhodinal.html","C10H18O","free base","Rhodinal; 2,3-Dihydrocitral","CC(CCC=C(C)C)CC=O",3.018,1,0,5]
["S5592","Vitamin A","g10","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP39-NF34,BP2015","080702,080746,080860,080943,080952,080953,080955,080967,080985,083035,083114,083134,083190,083207,083351,083457,083665,083973,085479","Ophthalmology","Vitamin","Metabolism","Vitamin A (Retinol) is a naturally occuring fat-soluble vitamin that is important for normal vision, the immune system, and reproduction. It also plays roles in normal functioning of heart, lungs, kidneys, and other organs.",286.45,"68-26-8",57,198.99,-1,-3.49,"https://www.selleckchem.com/products/vitamin-a.html","C20H30O","free base","Retinol","CC(=C/CO)\\C=C\\C=C(C)\\C=C\\C1=C(C)CCCC1(C)C",5.316,0,1,5]
["S5594","(-)-(S)-α-terpineol","h10","L1300-24","in 10mM DMSO",null,"BP2019",null,"Others","Prostaglandin Receptor","GPCR & G Protein","(-)-(S)-α-terpineol, a natural monoterpene, is the major component of essential oils of several species of aromatic plants such as Origanium vulgare L. and Ocimum canum Sims which are widely used for medicinal purposes. It is widely used in the manufacturing of cosmetics, soaps, perfumes, antiseptic agents and is considered one of the most frequently used fragrance compounds. α-TPN has anticholinergic action and can block the interaction between PGE2 and GM1 receptors and cholera toxin.",154.25,"10482-56-1","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/alpha-terpineol.html","C10H18O","free base","N/A","CC1=CCC(CC1)C(C)(C)O",2.415,0,0,1]
["S5596","(1S)-(-)-α-Pinene","a11","L1300-24","in 10mM DMSO",null,"BP2019",null,"Others","GABA Receptor","Neuronal Signaling","α-Pinene is found in the oils of many species of many coniferous trees, notably the pine and has insecticidal activity.  (1S)-(-)-α-Pinene is a monoterpene and shows sleep enhancing property through a direct binding to GABAA-benzodiazepine (BZD) receptors by acting as a partial modulator at the BZD binding site.",136.23,"7785-26-4","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/1s-alpha-pinene.html","C10H16","free base","N/A","CC1=CCC2CC1C2(C)C",2.872,0,0,0]
["S5597","(1R)-(-)-Menthyl acetate","b11","L1300-24","in 10mM DMSO",null,"BP2019;EP9.2;IP2010",null,"Others","Others","Others","(1R)-(-)-Menthyl acetate is a natural monoterpene which contributes to the smell and flavor of peppermint.",198.3,"2623-23-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"https://www.selleckchem.com/products/1r-menthyl-acetate.html","C12H22O2","free base","N/A","CC(C)C1CCC(C)CC1OC(C)=O",3.158,2,0,3]
["S5599","Sodium cholate","c11","L1300-24","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,BP2017",null,"Metabolic Disease","Others","Others","Sodium cholate (NaCh) is the sodium salt of the naturally occurring cholic acid, a bile salt produced by the liver, with strong solubilization capacity of water-insoluble substances.",430.55,"361-09-1",86,199.74,0,0,"http://selleckchem.com/products/sodium-cholate.html","C24H39O5.Na","sodium salt","N/A","[Na+].CC(CCC([O-])=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CC(O)C12C",1.438,0,3,4]
["S5604","Diphenylamine Hydrochloride","d11","L1300-24","in 10mM DMSO",null,"BP2016;USP36-NF31;IP2010",null,"Others","OXPHOS","Apoptosis","Diphenylamine (N-Phenylbenzenamine, Anilinobenzene, C.I. 10355), a derivative of aniline, is widely used as an industrial antioxidant, dye mordant and reagent and is also employed in agriculture as a fungicide and antihelmintic. Diphenylamine can inhibits oxidative phosphorylationsignificantly, although its inhibition potency was weaker than that of NSAIDs with a diphenylamine structure.",205.68,"537-67-7",41,199.34,1,4.86,"http://www.selleckchem.com/products/diphenylamine-hydrochloride.html","C12H12ClN","Hydrochloride","N-Phenylbenzenamine, Anilinobenzene, C.I. 10355","Cl.N(C1=CC=CC=C1)C2=CC=CC=C2",3.762,0,1,2]
["S5614","(+)-Longifolene","e11","L1300-24","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Others","Others","(+)-Longifolene is a naturally occurring, oily liquid hydrocarbon found primarily in the high-boiling fraction of certain pine resins",204.35,"475-20-7","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://selleckchem.com/products/longifolene.html","C15H24","free base","N/A","CC1(C)CCCC2(C)C3CCC(C13)C2=C",4.177,0,0,0]
["S5618","Hippuric acid","f11","L1300-24","in 10mM DMSO","NDC",null,null,"Others","Others","Others","Hippuric Acid (2-Benzamidoacetic acid, Benzoylglycine) is an acyl glycine produced by the conjugation of benzoic acid and glycine, found as a normal component in urine as a metabolite of aromatic compounds from food.",179.17,"495-69-2",35,195.35,0,0,"http://selleckchem.com/products/hippuric-acid.html","C9H9NO3","free base","2-Benzamidoacetic acid, Benzoylglycine","OC(=O)CNC(=O)C1=CC=CC=C1",0.519,2,1,3]
["S5619","Betahistine","g11","L1300-24","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017",null,"Neurological Disease","Histamine Receptor","Neuronal Signaling","Betahistine is an antivertigo drug that primarily acts as a histamine H1 agonist.",136.19,"5638-76-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",10,0,0,"https://www.selleckchem.com/products/betahistine.html","C8H12N2","free base",0,"CNCCC1=NC=CC=C1",0.68,1,1,3]
["S5621","Cilastatin","h11","L1300-24","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017,IP2010","090577,090825,091007,050587,050630,062756","Infection","Others","Metabolism","Cilastatin(MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor.",358.45,"82009-34-5",90,251.08,7,19.53,"http://selleckchem.com/products/cilastatin.html","C16H26N2O5S","free base","MK0791","CC1(C)CC1C(=O)N\\C(=C/CCCCSCC(N)C(O)=O)C(O)=O",-1.459,3,2,11]
["S5623","Bedaquiline","a2","L1300-25","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"204384","Infection/Respiratory Disease","ATPase","Transmembrane Transporters","Bedaquiline (TMC-207, R207910), a diarylquinoline, binds to subunit c of mycobacterial ATP synthase and inhibits its activity. It is highly selective for mycobacterial ATP synthase enzyme compared to homologous eukaryotic enzyme (Selectivity Index >20 000).",555.5,"843663-66-1",12,21.6,"<1",0,"https://www.selleckchem.com/products/bedaquiline.html","C32H31BrN2O2","free base","TMC-207, R207910","COC1=NC2=CC=C(Br)C=C2C=C1C(C3=CC=CC=C3)C(O)(CCN(C)C)C4=CC=CC5=CC=CC=C45",6.933,2,0,8]
["S5625","Ammonium lactate","b2","L1300-25","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia","075570,075575,075774,075883,076216,076829","Immunology","Bacterial","Microbiology","Ammonium lactate (Lac-hydrin) is the ammonium salt of lactic acid with mild anti-bacterial properties.",107.11,"515-98-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",10,0,0,"https://www.selleckchem.com/products/ammonium-iactate.html","C3H9NO3","free base","Lac-hydrin","[NH4+].CC(O)C([O-])=O",-3.725,0,1,1]
["S5626","Benzalkonium chloride","c2","L1300-25","in 10mM DMSO","CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,IP2010",null,"Infection/Inflammation","Others","Others","Benzalkonium chloride, a detergent and preservative found in health care and household products, is an established irritant.",0,"63449-41-2, 8001-54-5",51,10,0,0,"https://www.selleckchem.com/products/benzalkonium-chloride.html","C15H26ClNR","free base","N/A","[Cl-].CCCCCC[N+](C)(C)CC1=CC=CC=C1",0.85,0,0,7]
["S5627","Amsacrine hydrochloride","d2","L1300-25","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Cancer/Hematology","Topoisomerase","DNA Damage/DNA Repair","Amsacrine hydrochloride (m-AMSA, acridinyl anisidide) is the hydrochloride salt form of amsacrine, which is an inhibitor of topoisomerase II with antineoplastic activity.",429.92,"54301-15-4",85,197.71,0,0,"https://www.selleckchem.com/products/amsacrine-hydrochloride.html","C21H20ClN3O3S","free base","m-AMSA, acridinyl anisidide","Cl.COC1=CC(=CC=C1NC2=C3C=CC=CC3=NC4=C2C=CC=C4)N[S](C)(=O)=O",4.18,4,2,5]
["S5637","Cefotiam Hexetil Hydrochloride","e2","L1300-25","in 10mM DMSO","PMDA","KP Ⅹ,JP17",null,"Others","Antibiotics,Bacterial","Microbiology","Cefotiam Hexetil Hydrochloride is the hydrochloride salt of cefotiam hexetil. Cefotiam is a semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity.",768.76,"95789-30-3",100,130.08,-1,-1.3,"https://www.selleckchem.com/products/cefotiam-hexetil-hydrochloride.html","C27H39Cl2N9O7S3","free base",0,"Cl.Cl.CC(OC(=O)OC1CCCCC1)OC(=O)C2=C(CSC3C(NC(=O)CC4=CSC(=N4)N)C(=O)N23)CSC5=NN=N[N]5CCN(C)C",2.966,11,2,16]
["S5638","Cefozopran hydrochloride","f2","L1300-25","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Infection","Bacterial","Microbiology","Cefozopran Hydrochloride is the hydrochloride salt form of cefozopran, a semi-synthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity.",551.99,"113981-44-5",100,181.16,-1,-1.81,"https://www.selleckchem.com/products/cefozopran-hydrochloride.html","C19H18ClN9O5S2","free base",0,"Cl.CO/N=C(C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)C[N+]3=C4C=CC=N[N]4C=C3)/C5=NSC(=N5)N",-1.752,7,2,7]
["S5641","Rhodamine B","g2","L1300-25","in 10mM DMSO",null,"EP10.2, USP43-NF38, Ph.Int_6th, IP2010",null,"Others","Dyes","Others","Rhodamine B is used as a tracer dye in water to determine the rate and direction of flow and transport. It is a staining fluorescent dye used in fluorescence microscopy, flow cytometry, fluorescence correlation spectroscopy and ELISA in biotechnology fields.",479.01,"81-88-9",96,200.41,-1,-2.09,"https://www.selleckchem.com/products/rhodamine-b.html","C28H31ClN2O3",0,0,"[Cl-].CCN(CC)C1=CC2=C(C=C1)C(=C3C=CC(C=C3O2)=[N+](CC)CC)C4=C(C=CC=C4)C(O)=O",2.547,2,0,7]
["S5647","Emedastine Difumarate","h2","L1300-25","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37,EP9.1","020706","Immunology/Inflammation/Ophthalmology","Histamine Receptor","Neuronal Signaling","Emedastine Difumarate (Rapimine, Emedastine fumarate) is the difumarate salt form of emedastine, a second generation, selective histamine H1 receptor antagonist with anti-allergic activity.",534.56,"87233-62-3",100,187.07,100,187.07,"http://selleckchem.com/products/emedastine-difumarate.html","C17H26N4O.2C4H4O4","Difumarate","Rapimine, Emedastine fumarate","CCOCC[N]1C2=C(C=CC=C2)N=C1N3CCCN(C)CC3.OC(=O)\\C=C\\C(O)=O.OC(=O)\\C=C\\C(O)=O",-0.464,6,0,9]
["S5648","Iguratimod","a3","L1300-25","in 10mM DMSO","CFDA,PMDA",null,null,"Immunology/Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Iguratimod (T-614) is a small molecule compound with anti-inflammatory and immunomodulatory actions and used for the treatment of rheumatoid arthritis.",374.37,"123663-49-0",50,133.56,0,0,"http://selleckchem.com/products/iguratimod.html","C17H14N2O6S","free base","T-614","C[S](=O)(=O)NC1=CC2=C(C=C1OC3=CC=CC=C3)C(=O)C(=CO2)NC=O",0.605,6,2,5]
["S5649","Hydroxyzine pamoate","b3","L1300-25","in 10mM DMSO","FDA,DMF,NDC,PMDA","USP42-NF37,JP17","040156,081127,081128,081129,081165,086183,086695,086697,086698,086705,086728,086840,087479,087656,087657,087658,087760,087761,087767,087790,088392,088393,088487,088488,088496,088593,088594,088595,089031,089032,089033,089145,089146,201507","Immunology/Psychotic disorders","Histamine Receptor","Neuronal Signaling","Hydroxyzine Pamoate is the pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties.",763.27,"10246-75-0",100,131.01,-1,-1.31,"https://www.selleckchem.com/products/hydroxyzine-pamoate.html","C44H43ClN2O8","free base",0,"OCCOCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3.OC(=O)C4=C(O)C(=C5C=CC=CC5=C4)CC6=C7C=CC=CC7=CC(=C6O)C(O)=O",1.794,3,3,12]
["S5651","Dexrazoxane","c3","L1300-25","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","076068,200752,207321","Cardiovascular Disease","Others","Others","Dexrazoxane (ICRF-187) is an anticancer drug able to block mitosis and to arrest dividing cells. It is an iron chelator and provides cardioprotection against anthracycline toxicity.",268.27,"24584-09-6",54,201.29,"<1",0,"http://selleckchem.com/products/dexrazoxane.html","C11H16N4O4","free base","ICRF-187","CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2",-2.104,4,2,3]
["S5652","Elbasvir","d3","L1300-25","in 10mM DMSO","FDA,EMA,NDC,PMDA",null,"208261","Infection","HCV Protease","Proteases","Elbasvir (MK8742) is an NS5A inhibitor, preventing hepatitis C viral RNA replication and virion assembly. Median EC50 values range from 0.2 to 3600 pmol/L, based on genotype.",882.02,"1370468-36-2",100,113.38,"<1",0,"http://selleckchem.com/products/elbasvir.html","C49H55N9O7","free base","MK8742","COC(=O)NC(C(C)C)C(=O)N1CCCC1C2=NC=C([NH]2)C3=CC4=C(C=C3)C5=CC6=C(C=CC(=C6)C7=CN=C([NH]7)C8CCCN8C(=O)C(NC(=O)OC)C(C)C)[N]5C(O4)C9=CC=CC=C9",7.424,9,4,13]
["S5653","Indigo carmine","e3","L1300-25","in 10mM DMSO","CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,IP2010",null,"Others","Others","Others","Indigo carmine (Indigotine, 5,5′-indigodisulfonic acid sodium salt, Brilliant Indigo) is an indicator at pH 11.5-14, changing from blue to yellow. It has a role as a food colouring and a histological dye.",466.35,"860-22-0",93,199.42,-1,-2.14,"https://www.selleckchem.com/products/indigo-carmine.html","C16H8N2Na2O8S2","free base","Indigotine, 5,5′-indigodisulfonic acid sodium salt, Brilliant Indigo","[Na+].[Na+].[O-][S](=O)(=O)C1=CC2=C(NC(/C2=O)=C\\3NC4=C(C=C(C=C4)[S]([O-])(=O)=O)C3=O)C=C1",-3.717,2,2,2]
["S5654","Indacaterol","f3","L1300-25","in 10mM DMSO","FDA,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","022383","Inflammation/Respiratory Disease","Adrenergic Receptor","Neuronal Signaling","Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and pKi of 5.48 for β2-adrenoceptor.",392.49,"312753-06-3",52,132.49,"<1",0,"http://selleckchem.com/products/indacaterol.html","C24H28N2O3","free base","N/A","CCC1=CC2=C(CC(C2)NCC(O)C3=CC=C(O)C4=C3C=CC(=O)N4)C=C1CC",3.93,1,4,6]
["S5655","Venlafaxine","g3","L1300-25","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","022104,076565,076690,077166,077515,077653,078057,078087,078301,078421,078517,078554,078627,078789,078865,078932,079098,090027,090071,090174,090555,090899,091123,091272,200834,201272,202036,204889,205468,206250","Psychotic disorders","Serotonin Transporter","Neuronal Signaling","Venlafaxine (Wy 45030) is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.",277.4,"93413-69-5",55,198.27,"<1",0,"http://selleckchem.com/products/venlafaxine.html","C17H27NO2",0,"Wy 45030","COC1=CC=C(C=C1)C(CN(C)C)C2(O)CCCCC2",3.022,1,0,5]
["S5656","Diphenylpyraline hydrochloride","h3","L1300-25","in 10mM DMSO","DMF,FDA,HMA","Martindale:The Extra Pharmacopoeia,BP2017","011945","Immunology/Inflammation","Dyes,Histamine Receptor","Neuronal Signaling","Diphenylpyraline hydrochloride is the hydrochloride salt form of diphenylpyraline, which is an antihistamine used in the treatment of allergic rhinitis, hay fever, and allergic skin disorders.",317.85,"132-18-3",63,198.21,-1,0,"http://www.selleckchem.com/products/diphenylpyraline-hydrochloride.html","C19H24ClNO","hydrochloride","N/A","Cl.CN1CCC(CC1)OC(C2=CC=CC=C2)C3=CC=CC=C3",3.738,1,0,4]
["S5657","Ertapenem sodium","a4","L1300-25","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia","207647,208790,209133","Infection","Antibiotics","Microbiology","Ertapenem Sodium (MK826) is the sodium salt of ertapenem, a long-acting, broad-spectrum antibiotic of β-lactam subclass.",497.5,"153773-82-1",100,201.01,100,201.01,"http://selleckchem.com/products/ertapenem-sodium.html","C22H24N3NaO7S","sodium salt","MK826","[Na+].CC(O)C1C2C(C)C(=C(N2C1=O)C([O-])=O)SC3CNC(C3)C(=O)NC4=CC(=CC=C4)C(O)=O",-4.602,3,3,7]
["S5658","Omeprazole Sodium","b4","L1300-25","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017","200882,202686,204657,205379,207181","Gastrointestinal Disease","P450 (e.g. CYP17),Proton Pump","Transmembrane Transporters","Omeprazole Sodium is the sodium salt form of omeprazole, which is a proton pump inhibitor and suppresses gastric acid secretion. Omeprazole Sodium is a metabolism-dependent inhibitor (MDI) of CYP2C19.",367.4,"95510-70-6",73,198.69,73,198.69,"http://www.selleckchem.com/products/omeprazole-sodium.html","C17H18N3NaO3S","Sodium Salt","N/A","COC1=CC2=C(C=C1)[N]([Na])C(=N2)[S](=O)CC3=NC=C(C)C(=C3C)OC",3.008,5,0,5]
["S5659","Emedastine","c4","L1300-25","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,BP2017","020706","Immunology/Inflammation/Ophthalmology","Histamine Receptor","Neuronal Signaling","Emedastine is a potent, high affinity histamine H1-receptor-selective antagonist with Ki of 1.3 ±0.1 nM for H1-receptors while considerably weaker at H2- (K1 = 49,067 ± 11,113 nM) and H3-receptors (Ki = 12,430 ± 1,282 nM).",302.41,"87233-61-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",10,0,0,"http://selleckchem.com/products/emedastine.html","C17H26N4O","free base","N/A","CCOCC[N]1C2=C(C=CC=C2)N=C1N3CCCN(C)CC3",2.492,2,0,5]
["S5661","Tiaprofenic acid","d4","L1300-25","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,BP2017",null,"Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Tiaprofenic acid (Tiaprofensaeure, Acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.",260.31,"33005-95-7",52,199.76,"<1",0,"http://selleckchem.com/products/tiaprofenic-acid.html","C14H12O3S","free base","Tiaprofensaeure, Acido tiaprofenico","CC(C(O)=O)C1=CC=C(S1)C(=O)C2=CC=CC=C2",3.606,2,0,4]
["S5662","Ranitidine","e4","L1300-25","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,EP9.2,KP Ⅹ,JP17,BP2017,IP2010","074794,210681","Gastrointestinal Disease","Histamine Receptor","Neuronal Signaling","Ranitidine(AH-19065) is an H2 histamine receptor antagonist that works by blocking histamine and thus decreasing the amount of acid released by cells of the stomach.",314.4,"66357-35-5",63,200.38,-1,-3.18,"https://www.selleckchem.com/products/ranitidine.html","C13H22N4O3S","free base","AH-19065","CNC(/NCCSCC1=CC=C(CN(C)C)O1)=C\\[N+]([O-])=O",1.039,1,2,10]
["S5663","Minaprine dihydrochloride","f4","L1300-25","in 10mM DMSO","DMF",null,null,"Psychotic disorders","MAO","Metabolism","Minaprine dihydrochloride is hydrochloride salt form of Minaprine, which acts as a reversible inhibitor of MAO-A in rats and weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.",371.3,"25905-77-5",74,199.3,74,199.3,"https://www.selleckchem.com/products/minaprine-dihydrochloride.html","C17H24Cl2N4O","free base",0,"Cl.Cl.CC1=CC(=NN=C1NCCN2CCOCC2)C3=CC=CC=C3",3.583,3,1,5]
["S5664","Orphenadrine Hydrochloride","g4","L1300-25","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,BP2017,IP2010","010653","Neurological Disease","NMDAR","Neuronal Signaling","Orphenadrine Hydrochloride is an uncompetitive NMDAR antagonist, H1 receptor antagonist and nonselective mAChR antagonist with muscle relaxant activity.",305.84,"341-69-5",61,199.45,-1,-3.27,"https://www.selleckchem.com/products/orphenadrine-hydrochloride.html","C18H24ClNO","free base",0,"Cl.CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2C",4.253,1,0,6]
["S5665","Drofenine Hydrochloride","h4","L1300-25","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","BChE","Neuronal Signaling","Drofenine hydrochloride is a potent competitive inhibitor of BChE. It is an anticholinergic that acts both at the level of the nerves and the muscle fibers.",353.93,"548-66-3",71,200.6,-1,0,"http://www.selleckchem.com/products/drofenine-hydrochloride.html","C20H32ClNO2","hydrochloride","N/A","Cl.CCN(CC)CCOC(=O)C(C1CCCCC1)C2=CC=CC=C2",5.106,2,0,9]
["S5666","Moxisylyte hydrochloride","a5","L1300-25","in 10mM DMSO","marketed in British","Martindale:The Extra Pharmacopoeia,BP2017",null,"Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Moxisylyte hydrochloride (thymoxamine) is an alpha-adrenergic blocking agent used for the treatment of Raynaud's disease.",315.84,"964-52-3",63,199.47,-1,0,"http://www.selleckchem.com/products/moxisylyte-hydrochloride.html","C16H26ClNO3","hydrochloride","thymoxamine hydrochloride","Cl.CC(C)C1=C(OCCN(C)C)C=C(C)C(=C1)OC(C)=O",3.782,3,0,7]
["S5667","Fruquintinib (HMPL-013)","b5","L1300-25","in 10mM DMSO","CFDA",null,null,"Cancer","VEGFR","Angiogenesis","Fruquintinib (HMPL-013) is a small molecule inhibitor with strong potency and high selectivity against VEGFR family. It inhibits VEGFR 1, 2, 3, with IC50 values of 33 nM, 35 nM and 0.5 nM, respectively and shows only weak inhibition of RET, FGFR-1 and c-kit kinases.",393.39,"1194506-26-7",6,15.25,"<1",0,"https://www.selleckchem.com/products/fruquintinib.html","C21H19N3O5",0,0,"CNC(=O)C1=C(C)OC2=CC(=CC=C12)OC3=C4C=C(OC)C(=CC4=NC=N3)OC",3.111,7,1,5]
["S5669","Isoxsuprine hydrochloride","c5","L1300-25","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017,IP2010",null,"Angiology","Adrenergic Receptor","Neuronal Signaling","Isoxsuprine hydrochloride is a beta-adrenergic agonist with vasodilator activity.",337.84,"579-56-6",68,201.28,4,11.84,"http://www.selleckchem.com/products/isoxsuprine-hydrochloride.html","C18H24ClNO3","hydrochloride","N/A","Cl.CC(COC1=CC=CC=C1)NC(C)C(O)C2=CC=C(O)C=C2",3.384,1,3,7]
["S5670","Chloropyramine hydrochloride","d5","L1300-25","in 10mM DMSO","marketed in Eastern Europe","Martindale:The Extra Pharmacopoeia",null,"Immunology/Inflammation","Histamine Receptor","Neuronal Signaling","Chloropyramine hydrochloride (Halopyramine) is a histamine receptor H1 antagonist and has anti-cholinergic, antispasmodic, and antiallergic effects.",326.26,"6170-42-9",65,199.23,-1,0,"http://www.selleckchem.com/products/chloropyramine-hydrochloride.html","C16H21Cl2N3","hydrochloride","Halopyramine hydrochloride","Cl.CN(C)CCN(CC1=CC=C(Cl)C=C1)C2=CC=CC=N2",4.149,1,0,6]
["S5673","Mivacurium chloride","e5","L1300-25","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia","078562","Neurological Disease","Others","Others","Mivacurium chloride is a rapid, non-depolarising, neuromuscular blocking agent of short duration, used therefore as anesthetic, to provide skeletal muscle relaxation in minor surgical operations, in emergency surgical procedures of short to intermediate duration and during intubation of the trachea.",1100.17,"106861-44-3",100,90.9,100,90.9,"http://www.selleckchem.com/products/mivacurium-chloride.html","C58H80Cl2N2O14","chloride","N/A","[Cl-].[Cl-].COC1=CC2=C(C=C1OC)C(CC3=CC(=C(OC)C(=C3)OC)OC)[N+](C)(CCCOC(=O)CC\\C=C\\CCC(=O)OCCC[N+]4(C)CCC5=C(C=C(OC)C(=C5)OC)C4CC6=CC(=C(OC)C(=C6)OC)OC)CC2",0.836,14,0,30]
["S5679","Dolasetron Mesylate","f5","L1300-25","in 10mM DMSO","FDA,CFDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","020623,020624","Gastroenterology","5-HT Receptor","Neuronal Signaling","Dolasetron Mesylate (Anzemet hydrate,MDL-73147EF) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.",420.48,"115956-13-3",84,199.77,28,66.59,"http://www.selleckchem.com/products/dolasetron-mesylate.html","C20H24N2O6S","Mesylate","Anzemet hydrate,MDL-73147EF","C[S](O)(=O)=O.O=C1CN2C3CC(CC2CC1C3)OC(=O)C4=C[NH]C5=C4C=CC=C5",1.621,3,1,3]
["S5680","(-)-Verbenone","g5","L1300-25","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","(-)-Verbenone (2-Pinen-4-one), an important component of the essential oil from rosemary, is an insect pheromone with a spicy odor and camphoraceous fragrance.",150.22,"1196-01-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",10,0,0,"https://www.selleckchem.com/products/verbenone.html","C10H14O","free base","2-Pinen-4-one","CC1=CC(=O)C2CC1C2(C)C",2.082,1,0,0]
["S5682","Methyl linolenate","h5","L1300-25","in 10mM DMSO",null,"EP9.2;BP2017;USP36-NF31",null,"Others","Others","Others","Methyl linolenate (Linolenic acid methyl ester, Methyl alpha-linolenate) is a fatty acid methyl ester derived from alpha-linolenic acid and acts as a plant metabolite and an insect attractant.",292.46,"301-00-8","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/methyl-linolenate.html","C19H32O2","Free Base","Linolenic acid methyl ester, Methyl alpha-linolenate","CC\\C=C/C/C=C\\C\\C=C/CCCCCCCC(=O)OC",6.197,2,0,14]
["S5683","Isoproterenol sulfate dihydrate","a6","L1300-25","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","010375,006905","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Isoproterenol Sulfate is the sulfate salt form of isoproterenol, a beta-adrenergic receptor agonist with bronchodilator activity.",556.62,"299-95-6",100,179.66,-1,0,"http://www.selleckchem.com/products/isoproterenol-sulfate-dihydrate.html","C22H40N2O12S","dihydrate","N/A","O.O.CC(C)NCC(O)C1=CC=C(O)C(=C1)O.CC(C)NCC(O)C2=CC=C(O)C(=C2)O.O[S](O)(=O)=O",1.177,0,8,8]
["S5685","Desoximetasone","b6","L1300-25","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ","073440,076510,077552,077770,078369,078657,090727,201005,202838,203234,203787,204272,204675,204965,205082,205206,205594,205620,206440,206441,206740,206792,208044,208101,208104,208124,208163,208164,209973,210980","Immunology/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Desoximetasone (Desoxymethasone, Desoximetasonum) is a synthetic glucocorticoid receptor agonist with metabolic, anti-inflammatory and immunosuppressive activity.",376.46,"382-67-2",75,199.22,"<1",0,"http://www.selleckchem.com/products/desoximetasone.html","C22H29FO4","Free Base","Desoxymethasone, Desoximetasonum","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1C(=O)CO",2.376,2,2,2]
["S5692","Mexenone","c6","L1300-25","in 10mM DMSO",null,"BP2019;Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Mexenone (Benzophenone-10) is a benzophenone-derived sunscreening agent.",242.27,"1641-17-4",48,198.13,-1,0,"http://www.selleckchem.com/products/mexenone.html","C15H14O3","Free Base","Benzophenone-10","COC1=CC(=C(C=C1)C(=O)C2=CC=C(C)C=C2)O",3.461,2,1,3]
["S5693","Levomilnacipran Hydrochloride","d6","L1300-25","in 10mM DMSO","FDA,DMF,NDC",null,"210790","Psychotic disorders","Serotonin Transporter","Neuronal Signaling","Levomilnacipran Hydrochloride is a selective serotonin and norepinephrine reuptake inhibitor with antidepressant activity.",282.81,"175131-60-9",57,201.55,57,201.55,"http://www.selleckchem.com/products/levomilnacipran-hydrochloride.html","C15H23ClN2O","Hydrochloride","N/A","Cl.CCN(CC)C(=O)C1(CC1CN)C2=CC=CC=C2",1.67,1,1,5]
["S5697","Isopropamide Iodide","e6","L1300-25","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","010744","Gastrointestinal Disease","Others","Others","Isopropamide iodide is a long-acting quaternary anticholinergic drug used in the treatment of peptic ulcer and other gastrointestinal disorders.",480.43,"71-81-8",96,199.82,11,22.9,"http://www.selleckchem.com/products/isopropamide-Iodide.html","C23H33IN2O","Iodide","N/A","[I-].CC(C)[N+](C)(CCC(C(N)=O)(C1=CC=CC=C1)C2=CC=CC=C2)C(C)C",-0.328,1,1,8]
["S5698","Ketorolac tromethamine salt","f6","L1300-25","in 10mM DMSO","FDA,DMF,HMA,EMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,IP2010","074754,074761,074790,074801,074802,074955,074993,075222,075228,075230,075284,075299,075348,075626,075631,075772,075784,076109,076209,076271,076583,076722,077201,077308,077942,077943,078145,078299,078399,078434,078721,078737,090017,091065,201155,203242,203376,203410,204216,205191,209900,210616","Inflammation","COX","Immunology & Inflammation","Ketorolac tromethamine is a synthetic pyrrolizine carboxylic acid derivative with anti-inflammatory, analgesic and antipyretic properties. It is a non-selective COX inhibitor with IC50s of 20 nM for both COX-1 and COX-2.",376.4,"74103-07-4",75,199.26,75,199.26,"http://www.selleckchem.com/products/ketorolac-tromethamine-salt.html","C19H24N2O6","tromethamine salt","N/A","NC(CO)(CO)CO.OC(=O)C1CC[N]2C1=CC=C2C(=O)C3=CC=CC=C3",-2.028,2,4,6]
["S5700","Phthalylsulfathiazole","g6","L1300-25","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Infection","Anti-infection","Microbiology","Phthalylsulfathiazole (Sulfathalidine) is a broad-spectrum antimicrobial that can treat different types of infections including intestinal.",403.43,"85-73-4",80,198.3,-1,-2.48,"https://www.selleckchem.com/products/phthalylsulfathiazole.html","C17H13N3O5S2","free base","Sulfathalidine","OC(=O)C1=C(C=CC=C1)C(=O)NC2=CC=C(C=C2)[S](=O)(=O)NC3=NC=CS3",1.729,5,2,6]
["S5701","Alvimopan dihydrate (LY246736 dihydrate)","h6","L1300-25","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Gastroenterology","Opioid Receptor","Neuronal Signaling","Alvimopan (LY-246736) is a potent, relatively nonselective opioid antagonist with Ki values of 0.77, 4.4, and 40 nM for the μ, δ, and κ opioid receptors, respectively, displaying >100-fold selectivity over other aminergic G-protein-coupled receptors.",460.56,"170098-38-1",92,199.76,-1,-2.17,"https://www.selleckchem.com/products/alvimopan-dihydrate.html","C25H36N2O6","free base",0,"O.O.CC1CN(CCC1(C)C2=CC=CC(=C2)O)CC(CC3=CC=CC=C3)C(=O)NCC(O)=O",0.096,2,2,8]
["S5702","Fenipentol","a7","L1300-25","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Inflammation","Others","Others","Fenipentol (1-phenylpentan-1-ol, 1-Phenyl-1-pentanol, 1-Phenylpentanol) is a member of benzenes and stimulates plasma secretion & exocrine pancreatic secretion.",164.24,"583-03-9","The physical form of the compound is liquid, which can be dissolved in any proportion.",10,0,0,"https://www.selleckchem.com/products/fenipentol.html","C11H16O","free base","1-phenylpentan-1-ol, 1-Phenyl-1-pentanol, 1-Phenylpentanol","CCCCC(O)C1=CC=CC=C1",3.039,0,1,4]
["S5703","Carvedilol Phosphate","b7","L1300-25","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017,IP2010","090132,204717","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity.",513.48,"610309-89-2",100,198.23,-1,-1.98,"https://www.selleckchem.com/products/carvedilol-phosphate.html","C24H29N2O8P.1/2H2O","Phosphate",0,"COC1=C(OCCNCC(O)COC2=CC=CC3=C2C4=C([NH]3)C=CC=C4)C=CC=C1.O[P](O)(O)=O",4.28,3,3,10]
["S5705","Raceanisodamine","c7","L1300-25","in 10mM DMSO","CFDA",null,null,"Neurological Disease","Others","Others","Raceanisodamine (7β-Hydroxyhyoscyamine) is the active ingredient of Chinese herbal extracts that has vasoactive activity used to treat acute disseminated intravascular coagulation in patients in bacteremic shock.",305.37,"17659-49-3",61,199.76,30,98.24,"http://selleckchem.com/products/raceanisodamine.html","C17H23NO4","free base","7β-Hydroxyhyoscyamine","CN1C2CC(O)C1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",0.63,2,2,5]
["S5709","Norgestrel","d7","L1300-25","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017,IP2010","201828,202875","Endocrinology","ROS","Immunology & Inflammation","Norgestrel (WY-3707, SH-70850, SH-850, FH 122-A) is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception. It also has strong neuroprotective activity.",312.45,"6533-00-2",62,198.43,"<1",0,"http://selleckchem.com/products/norgestrel.html","C21H28O2","free base","WY-3707, SH-70850, SH-850, FH 122-A","CCC12CCC3C(CCC4=CC(=O)CCC34)C1CCC2(O)C#C",4.771,1,0,1]
["S5710","Ambroxol","e7","L1300-25","in 10mM DMSO","CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,EP9.2,BP2017,IP2010",null,"Respiratory Disease","Sodium Channel","Transmembrane Transporters","Ambroxol, a substituted benzylamine, is an active metabolite of bromhexine. It is a potent inhibitor of the neuronal Na+ channels.",378.1,"18683-91-5",76,201,-1,-2.64,"https://www.selleckchem.com/products/ambroxol.html","C13H18Br2N2O",0,0,"NC1=C(Br)C=C(Br)C=C1CNC2CCC(O)CC2",2.739,0,3,3]
["S5713","Pravastatin","f7","L1300-25","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","076056,076341,076397,076445,076714,076939,077013,077491,077730,077751,077793,077904,077917,077987,079187,203367,206061,207068,209869","Cardiovascular Disease","HMG-CoA Reductase","Metabolism","Pravastatin(CS-514) is a lipoprotein-lowering drug via reversibly inhibiting hydroxymethylglutaryl-CoA (HMG-CoA) reductase and the synthesis of very-low-density lipoproteins.",424.53,"81093-37-0",85,200.22,85,200.22,"http://www.selleckchem.com/products/pravastatin.html","C23H36O7","Free Base","CS-514","CCC(C)C(=O)OC1CC(O)C=C2C=CC(C)C(CCC(O)CC(O)CC(O)=O)C12",2.156,3,3,11]
["S5714","lurasidone","g7","L1300-25","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"207948,207995,208002,208016,208028,208031,208037,208045,208049,208052,208055,208058,208060,208066,212091","Psychotic disorders","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Lurasidone (SM-13496) is a second-generation antipsychotic agent that exhibits full antagonism at dopamine D2 and serotonin 5-HT2A receptors with binding affinities Ki = 1 nM and Ki = 0.5 nM, respectively. It also has high affinity for serotonin 5-HT7 receptors (Ki = 0.5 nM), partial agonist activity at 5-HT1A receptors (Ki = 6.4 nM) and lacks affinity for histamine H1 and muscarinic M1 receptors.",492.68,"367514-87-2",7,14.21,"<1",0,"http://selleckchem.com/products/lurasidone.html","C28H36N4O2S","free base","SM-13496","O=C1C2C3CCC(C3)C2C(=O)N1CC4CCCCC4CN5CCN(CC5)C6=NSC7=CC=CC=C67",4.896,3,0,5]
["S5715","Atorvastatin","h7","L1300-25","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,IP2010","076477,077575,078773,090548,091226,091624,091650,202357,204846,204991,205300,205519,206536,207687,209288,209912,211933","Cardiovascular Disease/Hematology","Autophagy,HMG-CoA Reductase","Metabolism","Atorvastatin is a lipid lowering agent. It is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the rate-determining enzyme in cholesterol biosynthesis via the mevalonate pathway. Atorvastatin activates autophagy.",558.64,"134523-00-5",100,179.01,"<1",0,"http://www.selleckchem.com/products/atorvastatin.html","C33H35FN2O5","Free Base","N/A","CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C([N]1CCC(O)CC(O)CC(O)=O)C3=CC=C(F)C=C3)C4=CC=CC=C4",5.555,2,3,12]
["S5716","Abemaciclib (LY2835219)","a8","L1300-25","in 10mM DMSO","FDA,EMA,NDC,PMDA",null,"208716,208855","Cancer","CDK","Cell Cycle","Abemaciclib (LY2835219) is a cell cycle inhibitor selective for CDK4/6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively.",506.59,"1231929-97-7",6,11.84,"<1",0,"http://selleckchem.com/products/abemaciclib.html","C27H32F2N8","free base","LY2835219","CCN1CCN(CC1)CC2=CN=C(NC3=NC=C(F)C(=N3)C4=CC(=C5N=C(C)[N](C(C)C)C5=C4)F)C=C2",4.957,4,1,7]
["S5717","Acetohexamide","b8","L1300-25","in 10mM DMSO","FDA,DMF,PMDA","Martindale:The Extra Pharmacopoeia,JP17,USP39-NF34","070753,070754,070869,070870,071893,071894","Endocrinology/Metabolic Disease","Others","Others","Acetohexamide is an intermediate-acting, first-generation oral sulfonylurea with hypoglycemic activity. It exerts the blood-glucose-lowering effects by stimulating the pancreatic beta cells to secrete insulin and by helping the body use insulin efficiently.",324.4,"968-81-0",11,33.91,"<1",0,"http://selleckchem.com/products/acetohexamide.html","C15H20N2O4S","free base","N/A","CC(=O)C1=CC=C(C=C1)[S](=O)(=O)NC(=O)NC2CCCCC2",2.119,4,2,4]
["S5718","Acrivastine","c8","L1300-25","in 10mM DMSO","FDA,DMF,CFDA,NDC,","Martindale:The Extra Pharmacopoeia","019806","Immunology","Histamine Receptor","Neuronal Signaling","Acrivastine(BW825C) is an antihistamine medicine that relieves the symptoms of allergies.",348.44,"87848-99-5",10,28.7,-1,0,"http://www.selleckchem.com/products/acrivastine.html","C22H24N2O2","Free Base","BW825C","CC1=CC=C(C=C1)C(=C\\CN2CCCC2)/C3=CC=CC(=N3)\\C=C\\C(O)=O",1.566,2,0,6]
["S5719","Ceftizoxime sodium","d8","L1300-25","in 10mM DMSO","FDA,DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17,USP38-NF33","050560,063294,050589,050589","Infection","Antibiotics","Microbiology","Ceftizoxime sodium(SKF-88373) is a semisynthetic cephalosporin antibiotic that is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.",405.38,"68401-82-1",81,199.81,81,199.81,"http://www.selleckchem.com/products/ceftizoxime-sodium.html","C13H12N5NaO5S2","Sodium Salt","SKF-88373","[Na+].CO\\N=C(/C(=O)NC1C2SCC=C(N2C1=O)C([O-])=O)C3=CSC(=N3)N",-2.118,5,2,5]
["S5720","Glecaprevir","e8","L1300-25","in 10mM DMSO","FDA,EMA,NDC",null,"209394","Infection","HCV Protease","Proteases","Glecaprevir(ABT-493) is a hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease inhibitor that targets the the viral RNA replication.  It displays IC50 values ranging from 3.5 to 11.3 nM for clinical isolates of HCV genotypes 1a, 1b, 2a, 2b, 3a, 4a, 5a, and 6a.",838.87,"1365970-03-1",100,119.21,-1,0,"http://www.selleckchem.com/products/glecaprevir.html","C38H46F4N6O9S","Free Base","ABT-493","CC(C)(C)C1NC(=O)OC2CCCC2OC\\C=C\\C(F)(F)C3=NC4=C(C=CC=C4)N=C3OC5CC(N(C5)C1=O)C(=O)NC6(CC6C(F)F)C(=O)N[S](=O)(=O)C7(C)CC7",3.746,11,3,7]
["S5722","Oxantel Pamoate","f8","L1300-25","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","Parasite","Microbiology","Oxantel Pamoate is the pamoate salt form of oxantel, a tetrahydropyrimidine anthelmintic used against intesitnal worms, particularly in a veterinary setting.",604.65,"68813-55-8",100,165.38,-1,0,"http://www.selleckchem.com/products/oxantel-pamoate.html","C36H32N2O7","pamoate salt","N/A","CN1CCCN=C1\\C=C\\C2=CC(=CC=C2)O.OC(=O)C3=C(O)C(=C4C=CC=CC4=C3)CC5=C6C=CC=CC6=CC(=C5O)C(O)=O",6.008,3,3,6]
["S5724","Dichlorophen","g8","L1300-25","in 10mM DMSO","DMF",null,null,"Infection/Parasitology","Fungal","Microbiology","Dichlorophen (Dichlorophene, Bis(5-chloro-2-hydroxyphenyl)methane) is an anticestodal agent, fungicide, germicide, and antimicrobial agent.",269.12,"97-23-4",54,200.65,-1,-3.72,"https://www.selleckchem.com/products/dichlorophene.html","C13H10Cl2O2","free base","Dichlorophene, Bis(5-chloro-2-hydroxyphenyl)methane","OC1=CC=C(Cl)C=C1CC2=CC(=CC=C2O)Cl",4.649,0,2,2]
["S5726","Triiodothyronine","a9","L1300-25","in 10mM DMSO","CFDA",null,null,"Endocrinology","THR","Metabolism","Triiodothyronine (T3, Liothyronine, 3,3',5-Triiodo-L-thyronine) is a thyroid hormone that affects various physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.This product is soluble but easy to precipitate after freezing in DMSO. NaOH is recommended as a stock solution.",650.97,"6893-02-3",100,153.62,"<1",0,"http://www.selleckchem.com/products/triiodothyronine.html","C15H12I3NO4","Free Base","T3, Liothyronine, 3,3',5-Triiodo-L-thyronine","NC(CC1=CC(=C(OC2=CC=C(O)C(=C2)I)C(=C1)I)I)C(O)=O",1.448,2,2,5]
["S5727","Tetryzoline","b9","L1300-25","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017","086576","Ophthalmology","Adrenergic Receptor","Neuronal Signaling","Tetryzoline (Tetrahydrozoline) is an alpha-adrenergic agonist used in some over-the-counter eye drops and nasal sprays.",200.28,"84-22-0",40,199.72,-1,0,"http://www.selleckchem.com/products/tetryzoline.html","C13H16N2","Free Base","Tetrahydrozoline","C1CC(C2=NCCN2)C3=C(C1)C=CC=C3",2.185,1,1,1]
["S5728","Delapril Hydrochloride","c9","L1300-25","in 10mM DMSO","PMDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","ACE,RAAS","Endocrinology & Hormones","Delapril Hydrochloride (Alindapril) is the hydrochloride salt form of delapril, which is a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.",489,"83435-67-0",98,200.41,"<1",0,"https://www.selleckchem.com/products/delapril-hydrochloride.html","C26H33ClN2O5","hydrochloride","Alindapril Hydrochloride","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N(CC(O)=O)C2CC3=C(C2)C=CC=C3",1.253,4,1,12]
["S5729","Fosfosal","d9","L1300-25","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Fosfosal (2-phosphonoxy benzoic acid) is a non-acetylated salicylic acid derivative, with analgesic and anti-inflammatory activity, but without effects on PG biosynthesis in vitro.",218.1,"6064-83-1",43,197.16,-1,-4.59,"https://www.selleckchem.com/products/fosfosal.html","C7H7O6P","free base","2-phosphonoxy benzoic acid","OC(=O)C1=C(O[P](O)(O)=O)C=CC=C1",0.963,2,0,3]
["S5730","Alimemazine Tartrate","e9","L1300-25","in 10mM DMSO","PMDA,HMA","Martindale:The Extra Pharmacopoeia,JP17,BP2017",null,"Immunology","Others","Others","Alimemazine (Trimeprazine Tartrate, Methylpromazine Tartrate) is a phenothiazine derivative that is used as an antipruritic.",746.98,"4330-99-8",100,133.87,100,133.87,"https://www.selleckchem.com/products/alimemazine-tartrate.html","C40H50N4O6S2","tartrate","Trimeprazine Tartrate, Methylpromazine Tartrate","CC(CN(C)C)CN1C2=CC=CC=C2SC3=C1C=CC=C3.CC(CN(C)C)CN4C5=CC=CC=C5SC6=C4C=CC=C6.OC(C(O)C(O)=O)C(O)=O",1.315,2,2,11]
["S5732","Sebacic acid","f9","L1300-25","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Sebacic acid (1,8-Octanedicarboxylic acid) is a saturated, straight-chain naturally occurring dicarboxylic acid",202.25,"111-20-6",40,197.78,-1,-4.94,"https://www.selleckchem.com/products/sebacic-acid.html","C10H18O4","free base","1,8-Octanedicarboxylic acid","OC(=O)CCCCCCCCC(O)=O",2.378,2,0,9]
["S5733","Stearic acid","g9","L1300-25","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017",null,"Others","Others","Others","Stearic acid (Octadecanoic acid, Isostearic acid, Cetylacetic acid) is a natural saturated fatty acid found in animal and vegetable fats. It could be used as a food additive and used in soaps, cosmetics and detergents.",284.48,"57-11-4",57,200.37,-1,-3.52,"https://www.selleckchem.com/products/stearic-acid.html","C18H36O2","free base","Octadecanoic acid, Isostearic acid, Cetylacetic acid","CCCCCCCCCCCCCCCCCC(O)=O",7.305,1,0,16]
["S5734","Midodrine hydrochloride","h9","L1300-25","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","076449,076514,076577,077746,207169,207613","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Midodrine hydrochloride is the hydrochloride salt form of midodrine, an adrenergic alpha-1 agonist used as a vasopressor.",290.74,"43218-56-0",58,199.49,-1,0,"http://www.selleckchem.com/products/midodrine-hydrochloride.html","C12H19ClN2O4","Hydrochloride","N/A","Cl.COC1=CC=C(OC)C(=C1)C(O)CNC(=O)CN",-0.166,3,3,6]
["S5735","Midodrine","a10","L1300-25","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","076449,076514,076577,077746,207169,207613","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Midodrine belongs to the class of medications known as vasopressors. It is an adrenergic alpha-1 agonist.",254.28,"42794-76-3",51,200.57,-1,0,"http://www.selleckchem.com/products/midodrine.html","C12H18N2O4","Free Base","N/A","COC1=CC=C(OC)C(=C1)C(O)CNC(=O)CN",-0.548,3,3,6]
["S5736","Benzathine penicilline","b10","L1300-25","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA",null,"050131,050141,060014","Infection","Antibiotics,Bacterial","Microbiology","Benzathine penicilline (Benzathine penicillin G) is an antibiotic useful for the treatment of a number of bacterial infections.",909.12,"1538-09-6",100,110,-1,0,"http://www.selleckchem.com/products/benzathine-penicilline.html","C48H56N6O8S2","Free Base","Benzathine penicillin G","CC1(C)SC2C(NC(=O)CC3=CC=CC=C3)C(=O)N2C1C(O)=O.CC4(C)SC5C(NC(=O)CC6=CC=CC=C6)C(=O)N5C4C(O)=O.C(CNCC7=CC=CC=C7)NCC8=CC=CC=C8",-0.608,6,4,15]
["S5737","Diclofenac Epolamine","c10","L1300-25","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia","021234,206976","Immunology/Inflammation/Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Diclofenac Epolamine (DHEP, DIEP, diclofenac hydroxyethylpyrrolidine) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.",411.32,"119623-66-4",82,199.36,82,199.36,"http://www.selleckchem.com/products/diclofenac-epolamine.html","C20H24Cl2N2O3","Epolamine","DHEP, DIEP, diclofenac hydroxyethylpyrrolidine","OCCN1CCCC1.OC(=O)CC2=C(NC3=C(Cl)C=CC=C3Cl)C=CC=C2",1.58,1,2,6]
["S5739","Nebivolol","d10","L1300-25","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,IP2010","203659,203683,203741,203821,203828,203966,206729","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Nebivolol (Bystolic,R 065824) is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and also for left ventricular failure.",405.43,"118457-14-0",88,217.05,-1,0,"http://www.selleckchem.com/products/nebivolol.html","C22H25F2NO4","Free Base","Bystolic,R 065824","OC(CNCC(O)C1CCC2=CC(=CC=C2O1)F)C3CCC4=C(O3)C=CC(=C4)F",3.557,2,3,6]
["S5740","Palonosetron","e10","L1300-25","in 10mM DMSO","FDA,DMF,HMA,EMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","090713,201533,202521,203050,204289,204702,204731,205648,205870,206396,206416,206801,206802,207005,207364,207963,208109,209287","Gastroenterology","5-HT Receptor","Neuronal Signaling","Palonosetron (RS25259, RS 25259 197) is a 5-HT3 antagonist with Ki value of 0.17 nM. It is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).",296.41,"135729-61-2",59,199.05,-1,0,"http://www.selleckchem.com/products/palonosetron.html","C19H24N2O","Free Base","RS25259, RS 25259 197","O=C1N(CC2CCCC3=C2C1=CC=C3)C4CN5CCC4CC5",2.745,1,0,1]
["S5741","Quetiapine","f10","L1300-25","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,JP17,BP2017,IP2010","077380,077745,078679,090120,090323,090482,090681,090749,090757,090960,091388,200363,201109,201190,201504,201762,202152,202228,202674,202939,203150,203359,203390,204203,204253,206252,206260,207655,208947,209497,209635,211405","Psychotic disorders","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Quetiapine(ICI204636) is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.Quetiapine is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine is a dopamine receptor antagonist with a pIC50 of 6.33 for human D2 receptor. Quetiapine have moderate to high affinity for the human D2, HT1A, 5-HT2A, 5-HT2C receptor with pKis of 7.23, 5.74, 7.54, 5.55.",383.51,"111974-69-7",77,200.78,-1,0,"http://www.selleckchem.com/products/quetiapine.html","C21H25N3O2S","Free Base","ICI204636","OCCOCCN1CCN(CC1)C2=NC3=CC=CC=C3SC4=C2C=CC=C4",2.656,2,1,6]
["S5742","Deferoxamine mesylate (Ba 33112)","g10","L1300-25","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","USP42-NF37,IP2010","076019,076806,078086,078718,207384","Hematology","Autophagy,Beta Amyloid,Ferroptosis,HIF","Autophagy","Deferoxamine mesylate (Ba 33112, Desferrioxamine B, DFOM, NSC 644468) is the mesylate salt of Deferoxamine, which forms iron complexes and is used as a chelating agent. Deferoxamine is a ferroptosis inhibitor that stabilizes HIF-1α expression and improves HIF-1α transactivity in hypoxic and hyperglycemic states in vitro. Deferoxamine decreases beta-amyloid (Aβ) deposition and induces autophagy.Please do not prepare stock solutions with normal saline or PBS, as precipitation may occur.",656.79,"138-14-7",100,152.26,-1,0,"http://www.selleckchem.com/products/deferoxamine-mesylate.html","C26H52N6O11S","mesylate","Desferrioxamine B, DFOM, NSC 644468","CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN.C[S](O)(=O)=O",-1.304,5,3,23]
["S5743","γ-Linolenic acid","h10","L1300-25","in 10mM DMSO","CFDA",null,null,"Nutritional support","Others","Others","γ-Linolenic Acid (18:3, n-6), the Δ6-desaturase product of linolenic acid,  is an unsaturated fatty acid found primarily in vegetable oils.",278.43,"506-26-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/linolenic-acid.html","C18H30O2","Free Base","N/A","CCCCC\\C=C/C/C=C\\C\\C=C/CCCCC(O)=O",5.971,1,0,13]
["S5747","Morantel tartrate","a11","L1300-25","in 10mM DMSO",null,"USP41-NF36;BP2017;Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","AChR","Neuronal Signaling","Morantel (CP-12009-18, UK 296418) is a positive allosteric modulator of neuronal nicotinic acetylcholine receptors (nAChRs).",370.42,"26155-31-7",74,199.77,-1,0,"http://www.selleckchem.com/products/morantel-tartrate.html","C16H22N2O6S","tartrate","CP-12009-18 tartrate, UK 296418 tartrate","CN1CCCN=C1/C=C/C2=C(C)C=CS2.OC(C(O)C(O)=O)C(O)=O",0.629,3,2,5]
["S5749","Chlorpromazine","b11","L1300-25","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017,IP2010","040224,040231,080340,080365,080370,080403,080439,083329,083386,083549,083574,083575,084112,084113,084114,084115,084411,084412,084413,084414,084415,084789,084800,084801,084802,084803,084911,085331,085484,085591,085748,085750,085751,085752,085956,085957,085958,085959,085960,086712,086863,087032,087053,087645,087646,087783,087865,087878,087880,087884,088038,089563,209755","Neurological Disease/Psychotic disorders","5-HT Receptor,Dopamine Receptor,Potassium Channel,Sodium Channel","Neuronal Signaling","Chlorpromazine (CPZ) is a low-potency typical antipsychotic agent that is used to treat psychotic disorders such as schizophrenia. Chlorpromazine (CPZ) inhibits 5-HT(2A) receptor and dopamine D2 in vitro. Chlorpromazine (CPZ) also inhibits sodium channel and blocks HERG potassium channels with IC50 of 21.6 μM.",318.86,"50-53-3",64,200.72,-1,0,"http://www.selleckchem.com/products/chlorpromazine.html","C17H19ClN2S","Free Base","CPZ","CN(C)CCCN1C2=C(SC3=C1C=C(Cl)C=C3)C=CC=C2",4.739,0,0,4]
["S5750","DL-Norepinephrine hydrochloride","c11","L1300-25","in 10mM DMSO","DMF, CFDA, NDC, PMDA","EP10.4, JP17, IP2010",null,"Metabolic Disease","Adrenergic Receptor","Neuronal Signaling","Norepinephrine (noradrenaline) is the neurotransmitter at most sympathetic neuroeffector junctions and has pharmacologic effects on both α1 and β1 adrenoceptors.",205.64,"55-27-6",41,199.38,-1,0,"http://www.selleckchem.com/products/dl-norepinephrine-hydrochloride.html","C8H12ClNO3","hydrochloride","noradrenaline hydrochloride","Cl.NCC(O)C1=CC(=C(O)C=C1)O",0.323,0,4,2]
["S5752","Abametapir","d11","L1300-25","in 10mM DMSO","FDA, DMF",null,206966,"Parasite","MMP","Proteases","Abametapir (HA-44, BRN 0123183), the active ingredient of Xeglyze Lotion, is an inhibitor of metalloproteinases critical for louse survival and egg development.",184.24,"1762-34-1",37,200.83,-1,0,"http://www.selleckchem.com/products/abametapir.html","C12H12N2","Free Base","HA-44, BRN 0123183","CC1=CN=C(C=C1)C2=CC=C(C)C=N2",2.876,2,0,1]
["S5754","Baricitinib phosphate","e11","L1300-25","in 10mM DMSO","FDA,EMA,NDC,PMDA",null,"207924","Immunology/Inflammation","COVID-19,JAK","JAK/STAT","Baricitinib phosphate (INCB-028050, LY-3009104) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Baricitinib is found to reduce or interrupt the passage of the virus into target cells and is used in the treatment research for COVID-19.",469.41,"1187595-84-1",94,200.25,-1,0,"http://www.selleckchem.com/products/baricitinib-phosphate.html","C16H20N7O6PS","phosphate","INCB-028050 phosphate, LY-3009104 phosphate","CC[S](=O)(=O)N1CC(CC#N)(C1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4.O[P](O)(O)=O",-0.108,5,1,5]
["S5756","Methyl Stearate","f11","L1300-25","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.2;IP2010",null,"Others","Others","Others","Methyl Stearate (Methyl Octadecanoate, Stearic Acid methyl ester), found in cloves, is an antifoaming agent and fermentation nutrient.",298.5,"112-61-8",8,26.8,-1,0,"http://www.selleckchem.com/products/methyl-stearate.html","C19H38O2","Free Base","Methyl Octadecanoate, Stearic Acid methyl ester","CCCCCCCCCCCCCCCCCC(=O)OC",7.53,2,0,17]
["S5757","Isoeugenol","g11","L1300-25","in 10mM DMSO",null,"BP2019",null,"Immunology","Anti-infection","Microbiology","Isoeugenol (4-Propenylguaiacol), an essential oil constituent of nutmeg, clove, and cinnamon, shows antimicrobial activity.",164.2,"97-54-1","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/isoeugenol.html","C10H12O2","Free Base","4-Propenylguaiacol","COC1=C(O)C=CC(=C1)\\C=C\\C",2.525,1,1,2]
["S5759","Methyl linoleate","h11","L1300-25","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.2",null,"Others","Others","Others","Methyl linoleate (Linoleic acid methyl ester), found in cloves, is a fatty acid methyl ester of linoleic acid which is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes.",294.47,"112-63-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/methyl-linoleate.html","C19H34O2","Free Base","Linoleic acid methyl ester","CCCCC/C=C\\C\\C=C/CCCCCCCC(=O)OC",6.641,2,0,15]
["S5761","Citric acid","a2","L1300-26","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.0,Ph.Int_6th,JP17,BP2017,IP2010","205743,209589,021314,018519,202535,019481,018904","Metabolic Disease","Others","Others","Citric acid is a weak organic acid that occurs naturally in citrus fruits. It is an intermediate in the citric acid cycle.",192.12,"77-92-9",38,197.79,-1,0,"http://www.selleckchem.com/products/citric-acid.html","C6H8O7","Free Base","N/A","OC(=O)CC(O)(CC(O)=O)C(O)=O",-1.319,3,0,5]
["S5762","Methyl Oleate","b2","L1300-26","in 10mM DMSO",null,"EP7.0;BP2017;USP36-NF31",null,"Others","Others","Others","Methyl Oleate (oleic acid methyl ester, Methyl cis-9-Octadecenoate) is a methyl ester of oleic acid, which is a monounsaturated fatty acid and is one of the major components of membrane phospholipids.",296.49,"112-62-9","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/methyl-oleate.html","C19H36O2","Free Base","oleic acid methyl ester, Methyl cis-9-Octadecenoate","CCCCCCCC\\C=C/CCCCCCCC(=O)OC",7.086,2,0,16]
["S5763","D-Mannose","c2","L1300-26","in 10mM DMSO",null,"BP2015",null,"Cancer/Immunology/Infection/Inflammation","Others","Others","D-mannose is a naturally occurring simple sugar that may help your body cleanse the urinary tract and maintain a healthy bladder lining.",180.16,"3458-28-4",36,199.82,-1,0,"http://www.selleckchem.com/products/d-mannose.html","C6H12O6","Free Base","N/A","OCC1OC(O)C(O)C(O)C1O",-2.514,1,4,1]
["S5765","Sodium Dehydrocholate","d2","L1300-26","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Gastroenterology","Others","Others","Sodium Dehydrocholate is a semisynthetic bile acid made from cholic acid. It has been used for stimulation of biliary lipid secretion.",424.51,"145-41-5",85,200.23,-1,0,"http://www.selleckchem.com/products/sodium-dehydrocholate.html","C24H33NaO5","Free Base","N/A","[Na+].CC(CCC([O-])=O)C1CCC2C3C(CC(=O)C12C)C4(C)CCC(=O)CC4CC3=O",1.31,3,0,4]
["S5766","Alfuzosin","e2","L1300-26","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,KP Ⅹ,BP2017","079013,079014,079054,079056,079057,079060,090221,090284,203192","Others","Adrenergic Receptor","Neuronal Signaling","Alfuzosin(SL 77499), a quinazoline derivative, is a selective and competitive α1-adrenoceptor antagonist.",389.45,"81403-80-7",78,200.28,"<1",0,"http://www.selleckchem.com/products/alfuzosin.html","C19H27N5O4","Free Base","SL 77499","COC1=CC2=NC(=NC(=C2C=C1OC)N)N(C)CCCNC(=O)C3CCCO3",1.418,6,2,8]
["S5767","Aliskiren","f2","L1300-26","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","206665,021985,210709","Cardiovascular Disease","RAAS","Metabolism","Aliskiren(CGP 60536) is a renin inhibitor with antihypertensive activity.",551.76,"173334-57-1",100,181.24,6,10.87,"http://www.selleckchem.com/products/aliskiren.html","C30H53N3O6","Free Base","CGP 60536","COCCCOC1=C(OC)C=CC(=C1)CC(CC(N)C(O)CC(C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C",3.327,5,4,19]
["S5768","Fenoterol hydrobromide","g2","L1300-26","in 10mM DMSO","PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,BP2017",null,"Immunology","Adrenergic Receptor","Neuronal Signaling","Fenoterol hydrobromide (Phenoterol) is the the hydrobromide salt of fenoterol, a β2 adrenoreceptor agonist with bronchodilator activity.",384.26,"1944-12-3",77,200.39,11,28.63,"http://www.selleckchem.com/products/fenoterol-hydrobromide.html","C17H22BrNO4","hydrobromide","Phenoterol hydrobromide","Br.CC(CC1=CC=C(O)C=C1)NCC(O)C2=CC(=CC(=C2)O)O",2.904,0,5,6]
["S5769","Fenoterol","h2","L1300-26","in 10mM DMSO","PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,BP2017",null,"Immunology","Adrenergic Receptor","Neuronal Signaling","Fenoterol (Phenoterol) is a β2 adrenoreceptor agonist with bronchodilator activity.",303.35,"13392-18-2",61,201.09,"<1",0,"http://www.selleckchem.com/products/fenoterol.html","C17H21NO4","Free Base","Phenoterol","CC(CC1=CC=C(O)C=C1)NCC(O)C2=CC(=CC(=C2)O)O",2.413,0,5,6]
["S5776","Proflavine","a3","L1300-26","in 10mM DMSO","NDC","Martindale:The Extra Pharmacopoeia",null,"Infection","Bacterial","Microbiology","Proflavine (3,6-Diaminoacridine) is a disinfectant bacteriostatic against many gram-positive bacteria. It is a topical antiseptic used mainly in wound dressings.",209.25,"92-62-6",23,109.92,1,4.78,"http://www.selleckchem.com/products/proflavine.html","C13H11N3","Free Base","3,6-Diaminoacridine","NC1=CC2=NC3=CC(=CC=C3C=C2C=C1)N",1.86,1,2,0]
["S5778","Esmolol","b3","L1300-26","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","076323,076474,076573,201126,205520,206608,207107,208538","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Esmolol is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages.",295.37,"81147-92-4",59,199.75,59,199.75,"http://www.selleckchem.com/products/esmolol.html","C16H25NO4","Free Base","N/A","COC(=O)CCC1=CC=C(OCC(O)CNC(C)C)C=C1",1.978,3,2,10]
["S5779","Trimetazidine","c3","L1300-26","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,JP17,BP2017,IP2010",null,"Cardiovascular Disease","Others","Metabolism","Trimetazidine is an anti-ischemic (anti-anginal) metabolic agent, which improves myocardial glucose utilization through inhibition of long-chain 3-ketoacyl CoA thiolase activity and results in a reduction in fatty acid oxidation and a stimulation of glucose oxidation.",266.34,"5011-34-7","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/trimetazidine.html","C14H22N2O3","Free Base","N/A","COC1=CC=C(CN2CCNCC2)C(=C1OC)OC",1.275,3,1,5]
["S5780","Prazosin","d3","L1300-26","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017,IP2010","071745,071994,071995,072333,072352,072573,072574,072575,072577,072609,072705,072706,072707,072782,072783,072784,072921,072991,072992,210971","Cardiovascular Disease/Neurological Disease","Adrenergic Receptor","Neuronal Signaling","Prazosin is an α1-blocker that acts as an inverse agonist at alpha-1 adrenergic receptors. It is used to treat hypertension.",383.4,"19216-56-9",77,200.83,1,2.61,"http://www.selleckchem.com/products/prazosin.html","C19H21N5O4","Free Base","N/A","COC1=CC2=NC(=NC(=C2C=C1OC)N)N3CCN(CC3)C(=O)C4=CC=CO4",2.107,6,1,4]
["S5781","Raloxifene","e3","L1300-26","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","078193,090842,200825,204310,204491,206384,208206","Cancer/Endocrinology/Metabolic Disease","Estrogen/progestogen Receptor","Endocrinology & Hormones","Raloxifene (Keoxifene, Pharoxifene, LY-139481, LY-156758, CCRIS-7129) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women.",473.58,"84449-90-1",95,200.6,1,2.11,"http://www.selleckchem.com/products/raloxifene.html","C28H27NO4S","Free Base","Keoxifene, Pharoxifene, LY-139481, LY-156758, CCRIS-7129","OC1=CC=C(C=C1)C2=C(C(=O)C3=CC=C(OCCN4CCCCC4)C=C3)C5=C(S2)C=C(O)C=C5",6.461,2,2,7]
["S5782","Doxazosin","f3","L1300-26","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.8,JP17,BP2017,USP42-NF37,KP Ⅹ","075353,075426,075432,075453,075466,075509,075536,075574,075580,075609,075646,075750,076161,202824,205210,208719,209013","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Doxazosin(UK 33274) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.",451.48,"74191-85-8",31,68.66,1,2.21,"http://www.selleckchem.com/products/doxazosin.html","C23H25N5O5","Free Base","UK 33274","COC1=CC2=C(C=C1OC)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=C(O4)C=CC=C5)N",2.485,7,1,4]
["S5783","Montelukast","g3","L1300-26","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017,IP2010","078605,078723,079103,079142,090655,090926,090955,090984,091128,091414,091576,091588,200405,200889,201294,201508,201515,201522,201581,201582,202096,202468,202717,202776,202843,202859,202906,203037,203328,203366,203432,203438,203582,203795,204093,204290,204604,205683,205695,206112,207463,207464,208621,209011,209012,210431","Immunology","LTR","Immunology & Inflammation","Montelukast(MK0476) is a leukotriene receptor antagonist used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.",586.18,"158966-92-8",100,170.6,1,1.71,"http://www.selleckchem.com/products/montelukast.html","C35H36ClNO3S","Free Base","MK0476","CC(C)(O)C1=CC=CC=C1CCC(SCC2(CC2)CC(O)=O)C3=CC=CC(=C3)\\C=C\\C4=CC=C5C=CC(=CC5=N4)Cl",8.284,2,0,12]
["S5784","Vancomycin","h3","L1300-26","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8,KP Ⅹ,JP17,BP2017,IP2010","062845,062663,062879,062911,062912,062931,062933,063076,065397,065401,065432,065453,065455,065478,065490,065510,090250,090439,091377,091469,091554,200837,201048,201250,201251,202274,202275,202464,204107,204125,204360,205694,205779,205780,206243,206616,209481,210729,211962","Infection/Inflammation","Antibiotics,Antibiotics for Plant Cell Culture,Bacterial","Microbiology","Vancomycin is an antibiotic used to treat serious bacterial infections. It works by stopping the growth of bacteria.",1449.25,"1404-90-6",29,20.01,1,0.69,"http://www.selleckchem.com/products/vancomycin.html","C66H75Cl2N9O24","Free Base","N/A","CNC(CC(C)C)C(=O)NC1C(O)C2=CC(=C(OC3=C(OC4OC(CO)C(O)C(O)C4OC5CC(C)(N)C(O)C(C)O5)C6=CC(=C3)C(NC(=O)C(CC(N)=O)NC1=O)C(=O)NC7C(=O)NC(C(O)C8=CC(=C(O6)C=C8)Cl)C(=O)NC(C(O)=O)C9=C(C(=CC(=C9)O)O)C%10=C(O)C=CC7=C%10)C=C2)Cl",-2.926,14,18,13]
["S5787","Dronedarone","a4","L1300-26","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","206649","Cardiovascular Disease","Adrenergic Receptor","Transmembrane Transporters","Dronedarone (SR33589) is a derivative of amiodarone which is classified as a Class III antiarrhythmic agent. It shows rate-dependent inhibition of the rapid Na+ current, inhibits α and β-adrenergic receptors like Class II agents, exhibits blockade of K+ outward currents as the main mechanism of action of Class III, and effectively block slow Ca2+ inward currents (Class IV).",556.76,"141626-36-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/dronedarone.html","C31H44N2O5S","Free Base","SR33589","CCCCN(CCCC)CCCOC1=CC=C(C=C1)C(=O)C2=C(CCCC)OC3=C2C=C(N[S](C)(=O)=O)C=C3",7.015,5,1,18]
["S5795","Rasagiline","b4","L1300-26","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","201823,201889,201892,201899,201950,201970,201971,207004","Neurological Disease","MAO","Metabolism","Rasagiline (TVP-1012) is a novel selective and irreversible MAO-B propargylamine inhibitor with in vitro IC50s of 4.43 nM and 412 nM for MAO-B and MAO-A, respectively.",171.24,"136236-51-6",34,198.55,4,23.36,"http://www.selleckchem.com/products/rasagiline.html","C12H13N","Free Base","TVP-1012","C#CCNC1CCC2=C1C=CC=C2",3.119,0,1,2]
["S5802","Alprenolol hydrochloride","c4","L1300-26","in 10mM DMSO",null,"EP9.2;JP17;USP36-NF31;Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Alprenolol hydrochloride is the hydrochloride salt form of alprenolol, which is an beta adrenergic receptorantagonist and is used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.",285.81,"13707-88-5",57,199.43,57,199.43,"http://www.selleckchem.com/products/alprenolol-hydrochloride.html","C15H24ClNO2","Hydrochloride","N/A","Cl.CC(C)NCC(O)COC1=CC=CC=C1CC=C",3.021,1,2,8]
["S5805","Allopregnanolone","d4","L1300-26","in 10mM DMSO","FDA",null,"211371","Psychotic disorders","GABA Receptor","Neuronal Signaling","Allopregnanolone, a neurosteroid synthesized from progesterone in brain, acts as a highly potent positive allosteric modulator of the GABAA receptor.",318.49,"516-54-1",64,200.95,"<1",0,"http://www.selleckchem.com/products/allopregnanolone.html","C21H34O2","Free Base","N/A","CC(=O)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C",3.874,1,1,1]
["S5808","Relugolix","e4","L1300-26","in 10mM DMSO","marketed in Japan",null,null,"Cancer","GNRH Receptor","Endocrinology & Hormones","Relugolix (RVT-601, TAK-385) is a selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with IC50 of 0.33 nM and 0.32 nM for human GnRHR and monkey GnRHR, respectively.",623.63,"737789-87-6",61,97.81,"<1",0,"http://www.selleckchem.com/products/relugolix.html","C29H27F2N7O5S","Free Base","RVT-601, TAK-385","CONC(=O)NC1=CC=C(C=C1)C2=C(CN(C)C)C3=C(S2)N(CC4=C(F)C=CC=C4F)C(=O)N(C3=O)C5=NN=C(OC)C=C5",4.623,7,2,9]
["S5812","Choline Fenofibrate","f4","L1300-26","in 10mM DMSO","FDA,DMF",null,"200264,200750,200913 ,200920,201573,208705,022224","Nutritional support","PPAR","Metabolism","Choline fenofibrate(ABT-335) is a newly developed choline salt of fenofibric acid, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity that acts as an PPARα agonist.",421.91,"856676-23-8",5,11.85,9,21.33,"http://www.selleckchem.com/products/choline-fenofibrate.html","C22H28ClNO5","Free Base","ABT-335","CC(C)(OC1=CC=C(C=C1)C(=O)C2=CC=C(Cl)C=C2)C([O-])=O.C[N+](C)(C)CCO",1.111,2,1,7]
["S5816","Pyrvinium","g4","L1300-26","in 10mM DMSO","FDA","USP42-NF37,KP Ⅹ","011964,012485","Cancer/Infection","Parasite","Microbiology","Pyrvinium is an anthelmintic effective for pinworms.",1151.39,"3546-41-6",22,19.11,"<1",0,"http://www.selleckchem.com/products/pyrvinium.html","C75H70N6O6","Free Base","N/A","CN(C)C1=CC2=CC=C(/C=C/C3=C(C)[N](C(=C3)C)C4=CC=CC=C4)[N+](=C2C=C1)C.CN(C)C5=CC6=CC=C(/C=C/C7=C(C)[N](C(=C7)C)C8=CC=CC=C8)[N+](=C6C=C5)C.OC9=C(CC%10=C(O)C(=CC%11=C%10C=CC=C%11)C([O-])=O)C%12=C(C=CC=C%12)C=C9C([O-])=O",13.931,0,2,12]
["S5821","Linoleic acid","h4","L1300-26","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010",null,"Inflammation","Others","Others","Linoleic acid (9,12-octadecadienoic acid) is an essential fatty acid used in the biosynthesis of arachidonic acid and found in the lipids of cell membranes.,",280.45,"60-33-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/linoleic-acid.html","C18H32O2","Free Base","9,12-octadecadienoic acid","CCCCC/C=C\\C\\C=C/CCCCCCCC(O)=O",6.416,1,0,14]
["S5823","L-Pyroglutamic acid","a5","L1300-26","in 10mM DMSO","DMF",null,null,"Nutritional support","Others","Others","L-pyroglutamic acid (L-pyroglutamate, 5-Oxoproline, pidolic acid) is a natural nutrient and amino acid derived from glutamic acid. It is a metabolite in the glutathione cycle that is converted to glutamate by 5-oxoprolinase.",129.11,"98-79-3",26,201.38,26,201.38,"http://www.selleckchem.com/products/l-pyroglutamic-acid.html","C5H7NO3","Free Base","L-pyroglutamate, 5-Oxoproline, pidolic acid","OC(=O)C1CCC(=O)N1",-0.754,2,1,1]
["S5827","Citronellyl acetate","b5","L1300-26","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Others","Others","Citronellyl acetate (Citronellol acetate) is a natural flavouring ingredient.",198.3,"150-84-5","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/citronellyl-acetate.html","C12H22O2","Free Base","Citronellol acetate","CC(CCOC(C)=O)CCC=C(C)C",3.428,2,0,7]
["S5830","L-Xylose","c5","L1300-26","in 10mM DMSO","FDA","IP2010,USP40-NF35","018856","Others","Others","Others","L-Xylose is a synthesized levorotary form of Xylose, a sugar first isolated from wood.",150.13,"609-06-3",30,199.83,30,199.83,"http://www.selleckchem.com/products/l-xylose.html","C5H10O5","Free Base","N/A","OCC(O)C(O)C(O)C=O",-2.28,1,4,4]
["S5842","Cabergoline","d5","L1300-26","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","076310,077750,077843,078035,201503,202947,204735","Neurological Disease/Endocrinology","Dopamine Receptor","Neuronal Signaling","Cabergoline (FCE-21336), an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor.",451.6,"81409-90-7",90,199.29,1,2.21,"http://www.selleckchem.com/products/cabergoline.html","C26H37N5O2","Free Base","FCE-21336","CCNC(=O)N(CCCN(C)C)C(=O)C1CC2C(CC3=C[NH]C4=C3C2=CC=C4)N(CC=C)C1",3.036,2,2,8]
["S5843","Cinitapride Hydrogen Tartrate","e5","L1300-26","in 10mM DMSO","marketed India, Mexico, Pakistan and Spain","Martindale:The Extra Pharmacopoeia",null,"Gastroenterology","5-HT Receptor","Neuronal Signaling","Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors",552.57,"1207859-16-2",59,106.77,5,9.05,"http://www.selleckchem.com/products/cinitapride-hydrogen-tartrate.html","C25H36N4O10","Hydrogen Tartrate","N/A","CCOC1=CC(=C(C=C1C(=O)NC2CCN(CC2)CC3CCC=CC3)[N+]([O-])=O)N.OC(C(O)C(O)=O)C(O)=O",-2.325,4,4,10]
["S5847","Ethacrynate Sodium","f5","L1300-26","in 10mM DMSO","FDA,DMF,NDC","USP39-NF34","204634,205473,207758","Cardiovascular Disease/Metabolic Disease","Proton Pump","Transmembrane Transporters","Ethacrynate Sodium (ethacrynic acid sodium) is the sodium salt form of ethacrynic acid, which inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules.",325.12,"6500-81-8",65,199.93,65,199.93,"http://www.selleck.cn/products/ethacrynate-sodium.html","C13H11Cl2NaO4","Sodium","ethacrynic acid sodium","[Na+].CCC(=C)C(=O)C1=C(Cl)C(=C(OCC([O-])=O)C=C1)Cl",2.489,2,0,6]
["S5848","Frovatriptan Succinate","g5","L1300-26","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale the Extra Pharmacopoei","202931,204730,211292","Neurological Disease","5-HT Receptor","Neuronal Signaling","Frovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.",361.39,"158930-09-7",72,199.23,72,199.23,"http://www.selleck.cn/products/frovatriptan-succinate.html","C18H23N3O5","Succinate","SB 209509 Succinate,VML 251 Succinate","CNC1CCC2=C(C1)C3=C([NH]2)C=CC(=C3)C(N)=O.OC(=O)CCC(O)=O",-1.65,3,3,5]
["S5854","Xylometazoline","h5","L1300-26","in 10mM DMSO","CFDA,DMF,NDC,HMA","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,BP2017,IP2010",null,"Immunology/Inflammation","Others","Others","Xylometazoline (Ba-11391, Otrivine, Rhinoxilin) is a nasal vasoconstricting decongestant drug which is used to improve symptoms of nasal congestion, allergic rhinitis, and sinusitis.",244.38,"526-36-3",49,200.51,"<1",0,"http://www.selleck.cn/products/xylometazoline.html","C16H24N2","Free Base","Ba-11391, Otrivine, Rhinoxilin","CC1=CC(=CC(=C1CC2=NCCN2)C)C(C)(C)C",3.524,1,1,3]
["S5857","Trazodone","a6","L1300-26","in 10mM DMSO","FDA,CFDA,DMF,NDC,PMDA,HMA","Martindale the Extra Pharmacopoei,USP42-NF37,BP2017","070491,070492,070857,070858,070921,071112,071113,071139,071140,071196,071258,071405,071406,071514,071523,071524,071525,071636,072192,072193,072483,072484,073137,074357,090514,202180,205253,206923","Neurological Disease/Psychotic disorders","5-HT Receptor","Neuronal Signaling","Trazodone (AF-1161) is a 5-HT 2A/2C receptor antagonist that is used as an antidepressant for treating major depressive disorder and anxiety disorders.",371.86,"19794-93-5",45,121.01,"<1",0,"http://www.selleck.cn/products/trazodone.html","C19H22ClN5O","Free Base","AF-1161","ClC1=CC(=CC=C1)N2CCN(CCCN3N=C4C=CC=CN4C3=O)CC2",2.418,2,0,5]
["S5858","Vilazodone","b6","L1300-26","in 10mM DMSO","FDA,DMF,NDC",null,"208202,208209,208212","Psychotic disorders","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Vilazodone (EMD-68843, SB-659746A) is a novel antidepressant having a selective serotonin (5-HT) reuptake inhibitory and 5-HT1A receptor partial agonist activity. The affinity of vilazodone is much higher in the 5-HT reuptake site (Ki=0.1 nM) than in norepinephrine (Ki=56 nM) and dopamine (Ki=37 nM) sites.",441.52,"163521-12-8",88,199.31,1,2.26,"https://www.selleckchem.com/products/vilazodone.html","C26H27N5O2","Free Base","EMD-68843, SB-659746A","NC(=O)C1=CC2=C(O1)C=CC(=C2)N3CCN(CCCCC4=C[NH]C5=C4C=C(C=C5)C#N)CC3",4.536,2,2,7]
["S5859","Sancycline","c6","L1300-26","in 10mM DMSO","DMF",null,null,"Others","Antibiotics","Microbiology","Sancycline (Bonomycin, Norcycline, GS 2147) is a semi-synthetic tetracycline antibiotic.",414.41,"808-26-4",83,200.28,"<1",0,"http://www.selleck.cn/products/sancycline.html","C21H22N2O7","Free Base","Bonomycin, Norcycline, GS 2147","CN(C)C1C2CC3CC4=C(C(=CC=C4)O)C(=O)C3=C(O)C2(O)C(=O)C(=C1O)C(N)=O",-0.065,3,4,2]
["S5861","Lercanidipine","d6","L1300-26","in 10mM DMSO","CFDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Lercanidipine is a vasoselective dihydropyridine calcium antagonist used for the treatment of essential hypertension.",611.73,"100427-26-7",55,89.91,1,1.63,"http://www.selleckchem.com/products/lercanidipine.html","C36H41N3O6","Free Base","N/A","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OC(C)(C)CN(C)CCC(C3=CC=CC=C3)C4=CC=CC=C4)C",6.132,4,1,14]
["S5862","Metoclopramide","e6","L1300-26","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","204756","Gastroenterology","Dopamine Receptor","Neuronal Signaling","Metoclopramide is a dopamine antagonist used for the treatment of nausea and vomiting.",299.8,"364-62-5",60,200.13,1,3.34,"http://www.selleckchem.com/products/metoclopramide.html","C14H22ClN3O2","Free Base","N/A","CCN(CC)CCNC(=O)C1=C(OC)C=C(N)C(=C1)Cl",1.775,2,2,7]
["S5863","Metronidazole Benzoate","f6","L1300-26","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,Ph.Int_6th,BP2017,IP2010",null,"Infection","Bacterial","Microbiology","Metronidazole Benzoate (Benzoyl metronidazole) is the benzoate ester of metronidazole, a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.",275.26,"13182-89-3",55,199.81,1,3.63,"http://www.selleckchem.com/products/metronidazole-benzoate.html","C13H13N3O4","Benzoate","Benzoyl metronidazole","CC1=NC=C([N]1CCOC(=O)C2=CC=CC=C2)[N+]([O-])=O",1.706,3,0,6]
["S5868","DL-Menthol","g6","L1300-26","in 10mM DMSO","NDC","JP16",null,"Neurological Disease","Others","Others","DL-Menthol is a racemic mixture of D- and L-menthol. Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils.",156.27,"89-78-1",31,198.37,31,198.37,"http://www.selleck.cn/products/dl-menthol.html","C10H20O","Free Base","N/A","CC(C)C1CCC(C)CC1O",2.779,0,1,1]
["S5869","Cortisone","h6","L1300-26","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP35-NF30,BP2010,JP15","008126,008284,009458,080333,080341,080493,080630,080694,080731,080776,080836,083147,083471,083536,084246,085677,085736,085884","Endocrinology","Immunology & Inflammation related","Immunology & Inflammation","Cortisone is a pregnane steroid hormone and one of main substance released by the body as a reaction to stress. It suppresses the immune system, thus reducing inflammation and attendant pain and swelling at the site of the injury.",360.44,"53-06-5",72,199.76,1,2.77,"https://www.selleckchem.com/products/cortisone.html","C21H28O5","Free Base","N/A","CC12CCC(=O)C=C1CCC3C4CCC(O)(C(=O)CO)C4(C)CC(=O)C23",1.24,3,1,2]
["S5871","Trans-Tranilast","a7","L1300-26","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Immunology","Immunology & Inflammation related","Immunology & Inflammation","Trans-Tranilast is an antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.",327.33,"70806-55-2",65,198.58,1,3.06,"https://www.selleckchem.com/products/trans-tranilast.html","C18H17NO5","Free Base","N/A","COC1=C(OC)C=C(\\C=C\\C(=O)NC2=C(C=CC=C2)C(O)=O)C=C1",2.679,4,1,6]
["S5872","Estradiol dipropionate","b7","L1300-26","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Cancer/Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estradiol dipropionate (17-Beta-Estradiol-3,17-Dipropionate) is a semisynthetic, steroidal estrogen which has been used in hormone therapy for menopausal symptoms and low estrogen levels in women and in the treatment of gynecological disorders.",384.51,"113-38-2",21,54.61,1,2.6,"https://www.selleckchem.com/products/estradiol-dipropionate.html","C24H32O4","Free Base","17-Beta-Estradiol-3,17-Dipropionate","CCC(=O)OC1CCC2C3CCC4=C(C=CC(=C4)OC(=O)CC)C3CCC12C",5.56,4,0,6]
["S5873","Scopolamine HBr trihydrate","c7","L1300-26","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37,KP Ⅹ,EP9.2,JP17,IP2010","078830","Cardiovascular Disease/Neurological Disease","AChR","Neuronal Signaling","Scopolamine HBr is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55.3 nM.",438.31,"6533-68-2",88,200.77,88,200.77,"https://www.selleckchem.com/products/scopolamine-hbr-trihydrate.html","C17H28BrNO7","HBr trihydrate","N/A","O.O.O.Br.CN1C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",0.693,3,1,5]
["S5874","D-Carnitine hydrochloride","d7","L1300-26","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia",null,"Metabolic Disease","Mitochondrial Metabolism","Metabolism","D-Carnitine hydrochloride ((S)-Carnitine hydrochloride, (+)-Carnitine hydrochloride) is biosynthesized from lysine. It might be associated with the energy production from branched chain amino acids.",197.66,"10017-44-4",40,202.37,40,202.37,"https://www.selleckchem.com/products/d-carnitine-hydrochloride.html","C7H16ClNO3","hydrochloride","(S)-Carnitine hydrochloride, (+)-Carnitine hydrochloride","[Cl-].C[N+](C)(C)CC(O)CC(O)=O",-4.49,1,1,4]
["S5886","Hodostin","e7","L1300-26","in 10mM DMSO","FDA","JP17;USP42-NF37",null,"Neurological Disease; Cancer","AChR","Neuronal Signaling","Hodostin (Neostigmine methyl sulfate, Syntostigmin, Neostigmeth) is a reversible inhibitor of acetylcholinesterase (AChE), but can not cross the blood-brain barrier. It is used in the treatment of myasthenia gravis.",334.39,"51-60-5",67,200.36,67,200.36,"http://www.selleck.cn/products/hodostin.html","C13H22N2O6S","Free Base","Neostigmine methyl sulfate, Syntostigmin, Neostigmeth","CO[S]([O-])(=O)=O.CN(C)C(=O)OC1=CC(=CC=C1)[N+](C)(C)C",-2.302,3,0,4]
["S5887","Khellin","f7","L1300-26","in 10mM DMSO","DMF","Martindale the Extra Pharmacopoei",null,"Angiology/Neurological Disease","Anti-infection","Microbiology","Khellin (Methafrone, Visammin, Ammivisnagen, Khellinorm, Medekellin, Viscardan, Kalangin), a compound isolated from the seeds of Ammi Visnaga Lam (Umbelliferae), is used to treat a variety of maladies.",260.24,"82-02-0",26,99.91,"<1",0,"http://www.selleck.cn/products/khellin.html","C14H12O5","Free Base","Amicardine, Corafurone, Methafrone, Kelourin, Rykellin, Visammin, Ammispasmin, Ammivisnagen, Gynokhellan, Interkellin, Interkhellin, Amikellin, Ammipuran, Benecardin, Deltoside, Kelicorin, Khelangin, Khellamine, Khellanals, Khellinorm, Medekellin, Visammimix, Viscardan, Visnagalin, Kalangin, Kelincor","COC1=C2OC(=CC(=O)C2=C(OC)C3=C1OC=C3)C",2.172,5,0,2]
["S5900","Edrophonium chloride","g7","L1300-26","in 10mM DMSO","FDA,DMF,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017","040044,040131","Neurological Disease","AChR","Metabolism","Edrophonium chloride is the chloride salt of edrophonium, which is a rapid-onset, short-acting, readily reversible inhibitor of acetylcholinesterase.",201.69,"116-38-1",40,198.32,40,198.32,"http://www.selleckchem.com/products/edrophonium-chloride.html","C10H16ClNO","chloride","N/A","[Cl-].CC[N+](C)(C)C1=CC=CC(=C1)O",-2.026,0,1,2]
["S5901","Canagliflozin hemihydrate","h7","L1300-26","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"204042","Endocrinology/Metabolic Disease","SGLT","GPCR & G Protein","Canagliflozin hemihydrate is the hemihydrate form of canagliflozin, which is a SGLT2 inhibitor with IC50 of 2.2 nM for hSGLT2 in a cell-free assay, exhibits 413-fold selectivity over hSGLT1.",907.05,"928672-86-0",100,110.25,"<1",0,"http://www.selleckchem.com/products/canagliflozin-hemihydrate.html","C48H52F2O11S2","hemihydrate","N/A","O.CC1=C(CC2=CC=C(S2)C3=CC=C(F)C=C3)C=C(C=C1)C4OC(CO)C(O)C(O)C4O.CC5=C(CC6=CC=C(S6)C7=CC=C(F)C=C7)C=C(C=C5)C8OC(CO)C(O)C(O)C8O",6.686,2,8,10]
["S5909","Anagliptin","a8","L1300-26","in 10mM DMSO","PMDA",null,null,"Endocrinology/Metabolic Disease","DPP","Proteases","Anagliptin is an orally active and highly selective dipeptidyl peptidase-4 (DPP-4) inhibitor and exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation.",383.45,"739366-20-2",77,200.81,20,52.16,"http://www.selleckchem.com/products/anagliptin.html","C19H25N7O2","Free Base","N/A","CC1=N[N]2C=C(C=NC2=C1)C(=O)NCC(C)(C)NCC(=O)N3CCCC3C#N",-0.629,4,2,6]
["S5911","Bictegravir","b8","L1300-26","in 10mM DMSO","FDA,EMA,NDC",null,"210251","Infection","COVID-19,Integrase","Microbiology","Bictegravir (GS-9883) is a novel, potent, once-daily, unboosted inhibitor of HIV-1 integrase.",449.38,"1611493-60-7",90,200.28,"<1",0,"http://www.selleckchem.com/products/bictegravir.html","C21H18F3N3O5","Free Base","GS-9883","OC1=C2N(CC3OC4CCC(C4)N3C2=O)C=C(C(=O)NCC5=C(F)C=C(F)C=C5F)C1=O",0.646,4,2,3]
["S5921","Cyclopentolate Hydrochloride","c8","L1300-26","in 10mM DMSO","FDA,CFDA,DMF,NDC,PMDA","Martindale the Extra Pharmacopoei,EP8.8,KP Ⅹ,JP17,BP2017,USP38-NF33","084150,084863,089162,205937","Ophthalmology","AChR","Neuronal Signaling","Cyclopentolate is an antagonist of muscarinic acetylcholine receptors with Ki values of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively.",327.85,"5870-29-1",66,201.31,66,201.31,"http://www.selleck.cn/products/cyclopentolate-hydrochloride.html","C17H26ClNO3","Hydrochloride","N/A","Cl.CN(C)CCOC(=O)C(C1=CC=CC=C1)C2(O)CCCC2",2.871,2,0,7]
["S5923","Celiprolol hydrochloride","d8","L1300-26","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017",null,"Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Celiprolol is a β1-adrenoceptor antagonist with partial β2 agonist activity.",415.95,"57470-78-7",83,199.54,-1,0,"http://www.selleckchem.com/products/celiprolol-hydrochloride.html","C20H34ClN3O4","hydrochloride","N/A","Cl.CCN(CC)C(=O)NC1=CC(=C(OCC(O)CNC(C)(C)C)C=C1)C(C)=O",1.978,3,3,10]
["S5924","Olanexidine Hydrochloride semihydrate","e8","L1300-26","in 10mM DMSO","PMDA,HMA",null,null,"Others","Bacterial","Microbiology","Olanexidine (OPB-2045, OPB-2045G) is a monobiguanide compound with bactericidal activity.",417.8,"218282-71-4",82,196.27,1,2.39,"http://www.selleckchem.com/products/olanexidine-hydrochloride-semihydrate.html","C17H29Cl3N5O0.5","Hydrochloride semihydrate","OPB-2045, OPB-2045G","Cl.CCCCCCCCNC(=N)NC(=N)NCC1=CC=C(Cl)C(=C1)Cl",6.44,0,3,13]
["S5925","Olodaterol hydrochloride","f8","L1300-26","in 10mM DMSO","FDA,NDC,HMA",null,"203108","Inflammation/Respiratory Disease","Adrenergic Receptor","Neuronal Signaling","Olodaterol hydrochloride (BI-1744) is the hydrochloride salt form of Olodaterol, which is a long-acting beta2-adrenergic agonist.",422.9,"869477-96-3",85,200.99,85,200.99,"http://www.selleckchem.com/products/olodaterol-hydrochloride.html","C21H27ClN2O5","hydrochloride","BI-1744 HCl","Cl.COC1=CC=C(CC(C)(C)NCC(O)C2=C3OCC(=O)NC3=CC(=C2)O)C=C1",2.257,3,4,7]
["S5926","Pitolisant hydrochloride","g8","L1300-26","in 10mM DMSO","EMA",null,null,"Neurological Disease","Histamine Receptor","Neuronal Signaling","Pitolisant (Tiprolisant, BF-2649) acts as a high-affinity competitive antagonist (Ki=0.16 nM) and as an inverse agonist (EC50=1.5 nM) at the human histamine H3 receptor subtype.",332.31,"903576-44-3",66,198.61,66,198.61,"http://www.selleckchem.com/products/pitolisant-hydrochloride.html","C17H27Cl2NO","hydrochloride","Tiprolisant hydrochloride, BF-2649 HCl","Cl.ClC1=CC=C(CCCOCCCN2CCCCC2)C=C1",4.576,1,0,8]
["S5927","Proguanil","h8","L1300-26","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,Ph.Int_6th,BP2017,IP2010","091211,202362","Infection/Parasitology","Anti-infection,DHFR","Microbiology","Proguanil (chlorguanide, chloroguanide) is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.",253.73,"500-92-5",51,201,1,3.94,"http://www.selleckchem.com/products/proguanil.html","C11H16ClN5","Free Base","chlorguanide, chloroguanide","CC(C)NC(=N)NC(=N)NC1=CC=C(Cl)C=C1",2.226,0,3,6]
["S5935","Alvimopan","a9","L1300-26","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","021775","Gastroenterology","Opioid Receptor","Neuronal Signaling","Alvimopan (LY 246736, ADL 8-2698) is a potent, relatively nonselective opioid antagonist with Ki values of 0.77, 4.4, and 40 nM for the μ, δ, and κ opioid receptors, respectively, displaying >100-fold selectivity over other aminergic G-protein-coupled receptors.",424.53,"156053-89-3",85,200.22,1,2.36,"http://www.selleckchem.com/products/alvimopan.html","C25H32N2O4","Free Base","LY 246736, ADL 8-2698","CC1CN(CCC1(C)C2=CC=CC(=C2)O)CC(CC3=CC=CC=C3)C(=O)NCC(O)=O",0.51,2,2,8]
["S5936","Cefazolin","b9","L1300-26","in 10mM DMSO","FDA,CFDA,DMF,NDC,PMDA,HMA","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,KP Ⅹ,JP17,BP2017,IP2010","062688,062807,062831,062894,062988,062989,063016,063018,063207,063208,063209,063214,063216,064033,064169,064170,065047,065141,065143,065226,065244,065247,065280,065295,065296,065303,065306,065345,065395,201654,203661,209217","Infection","Antibiotics,Bacterial","Microbiology","Cefazolin(Cephazolin) is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.",454.51,"25953-19-9",91,200.22,"<1",0,"http://www.selleck.cn/products/cefazolin.html","C14H14N8O4S3","Free Base","Cephazolin","CC1=NN=C(SCC2=C(N3C(SC2)C(NC(=O)C[N]4C=NN=N4)C3=O)C(O)=O)S1",-1.333,8,1,7]
["S5938","Benazepril","c9","L1300-26","in 10mM DMSO","FDA,CFDA,DMF,NDC,PMDA,HMA","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,BP2017","076118,076211,076267,076333,076344,076402,076430,076476,076820,077128,078212,078848","Cardiovascular Disease","RAAS","Endocrinology & Hormones","Benazepril is used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. Benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor.",424.49,"86541-75-5",85,200.24,"<1",0,"http://www.selleck.cn/products/benazepril.html","C24H28N2O5","Free Base","N/A","CCOC(=O)C(CCC1=CC=CC=C1)NC2CCC3=C(C=CC=C3)N(CC(O)=O)C2=O",0.621,4,1,10]
["S5939","Bendamustine (SDX105)","d9","L1300-26","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale the Extra Pharmacopoei,USP42-NF37",211530,"Cancer","Others","Others","Bendamustine (SDX105) is a nitrogen mustard drug used in the treatment of chronic lymphocytic leukemia (CLL), multiple myeloma, and non-Hodgkin's lymphoma.",358.26,"16506-27-7",72,200.97,"<1",0,"http://www.selleck.cn/products/bendamustine.html","C16H21Cl2N3O2","Free Base","SDX105","C[N]1C(=NC2=C1C=CC(=C2)N(CCCl)CCCl)CCCC(O)=O",3.606,2,0,9]
["S5940","Bepotastine","e9","L1300-26","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale the Extra Pharmacopoei,JP17","206066,206080,206220","Immunology/Inflammation","COVID-19,Histamine Receptor","Neuronal Signaling","Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor that is indicated in allergic rhinitis, urticaria, and pruritus associated with skin disease.",388.89,"125602-71-3",78,200.57,78,200.57,"http://www.selleck.cn/products/bepotastine.html","C21H25ClN2O3","Free Base","N/A","OC(=O)CCCN1CCC(CC1)OC(C2=CC=C(Cl)C=C2)C3=CC=CC=N3",0.208,3,0,8]
["S5943","Bromhexine","f9","L1300-26","in 10mM DMSO","CFDA,PMDA,HMA","Martindale the Extra Pharmacopoei,EP8.8,KP Ⅹ,JP17,BP2017,IP2010",null,"Respiratory Disease","Others","Others","Bromhexine is an expectorant/mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus",376.13,"3572-43-8",75,199.4,"<1",0,"http://www.selleck.cn/products/bromhexine.html","C14H20Br2N2","Free Base","N/A","CN(CC1=CC(=CC(=C1N)Br)Br)C2CCCCC2",4.512,0,1,3]
["S5944","Butenafine","g9","L1300-26","in 10mM DMSO","FDA,CFDA,DMF,NDC,PMDA,HMA","Martindale the Extra Pharmacopoei,JP17",205181,"Infection","Fungal","Microbiology","Butenafine is a synthetic benzylamine antifungal agent.",317.47,"101828-21-1",63,198.44,"<1",0,"http://www.selleck.cn/products/butenafine.html","C23H27N","Free Base","N/A","CN(CC1=CC=C(C=C1)C(C)(C)C)CC2=CC=CC3=C2C=CC=C3",5.795,0,0,5]
["S5948","Amodiaquine","h9","L1300-26","in 10mM DMSO","FDA,CFDA,DMF","Martindale the Extra Pharmacopoei,USP42-NF37,Ph.Int_6th,IP2010","006441","Infection/Parasite","DNA/RNA Synthesis,Parasite","Microbiology","Amodiaquine is a synthetic aminoquinoline that acts by binding to the protozoal or parasitic DNA and preventing DNA and RNA production and subsequent protein synthesis. It is used for the therapy of malaria.",355.86,"86-42-0",71,199.52,"<1",0,"http://www.selleck.cn/products/amodiaquine.html","C20H22ClN3O","Free Base","N/A","CCN(CC)CC1=CC(=CC=C1O)NC2=CC=NC3=C2C=CC(=C3)Cl",4.76,1,2,6]
["S5950","Fingolimod","a10","L1300-26","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8","207939,207941,207945,207965,207971,207979,207983,207985,207991,207994,208001,208004,208008,208559,210252","Cancer","S1P Receptor","Neuronal Signaling","Fingolimod (FTY-720A, FTY-720) is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis.",307.47,"162359-55-9",13,42.28,1,3.25,"https://www.selleckchem.com/products/fingolimod.html","C19H33NO2","Free Base","FTY-720A, FTY-720","CCCCCCCCC1=CC=C(CCC(N)(CO)CO)C=C1",4.198,0,3,12]
["S5951","Cefoxitin","b10","L1300-26","in 10mM DMSO","FDA,CFDA,DMF,NDC,HMA","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,KP Ⅹ,BP2017","065011,065012,065050,065051,065238,065239,065312,065313,065414,065415,065464,065467","Infection","Antibiotics,Bacterial","Microbiology","Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.",427.45,"35607-66-0",85,198.85,"<1",0,"http://www.selleck.cn/products/cefoxitin.html","C16H17N3O7S2","Free Base","N/A","COC1(NC(=O)CC2=CC=CS2)C3SCC(=C(N3C1=O)C(O)=O)COC(N)=O",0.323,6,2,8]
["S5952","Baloxavir marboxil","c10","L1300-26","in 10mM DMSO","FDA,NDC,PMDA",null,210854,"Infection","Antiviral","Microbiology","Baloxavir marboxil(S-033188), a cap-endonuclease inhibitor, is an antiviral drug.",571.55,"1985606-14-1",100,174.96,"<1",0,"http://www.selleck.cn/products/baloxavir-marboxil.html","C27H23F2N3O7S","free base","S-033188","COC(=O)OCOC1=C2N(C=CC1=O)N(C3COCCN3C2=O)C4C5=C(CSC6=C4C=CC=C6)C(=C(F)C=C5)F",2.602,7,0,6]
["S6003","Ataluren (PTC124)","d10","L1300-26","in 10mM DMSO","EMA",null,null,"Others","CFTR","Transmembrane Transporters","Ataluren (PTC124) selectively induces ribosomal read-through of premature but not normal termination codons, with EC50 of 0.1 μM in HEK293 cells, may provide treatment for genetic disorders caused by nonsense mutations (e.g. CF caused by CFTR nonsense mutation). Phase 3.",284.24,"775304-57-9",57,200.53,"<1",0,"http://selleckchem.com/products/PTC124.html","C15H9FN2O3","free base","N/A","OC(=O)C1=CC=CC(=C1)C2=NOC(=N2)C3=CC=CC=C3F",2.98,4,0,3]
["S6006","Imidazole","e10","L1300-26","in 10mM DMSO",null,"IP2010;BP2010;Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Imidazole (1,3-diazole, glyoxaline, 1,3-diazacyclopenta-2,4-diene) is a heterocyclic aromatic organic compound. It can be incorporated into many important biological molecules and acts as a corrosion inhibitor for industrial applications.",68.08,"288-32-4",13,190.95,0,0,"http://www.selleck.cn/products/imidazole.html","C3H4N2","free base","1,3-diazole; glyoxaline; 1,3-diazacyclopenta-2,4-diene","[NH]1C=CN=C1",-0.283,1,1,0]
["S6007","Bisphenol A","f10","L1300-26","in 10mM DMSO","NDC",null,null,"Others","Others","Others","Bisphenol A is a starting material for the synthesis of plastics, primarily certain polycarbonates and epoxy resins, as well as some polysulfones and certain niche materials. It exhibits estrogen-mimicking, hormone-like properties.",228.29,"80-05-7",45,197.12,0,0,"http://www.selleck.cn/products/bisphenol-a.html","C15H16O2","free base","N/A","CC(C)(C1=CC=C(O)C=C1)C2=CC=C(O)C=C2",3.778,0,2,2]
["S6010","Sodium L-lactate","g10","L1300-26","in 10mM DMSO","HMA","JP17",null,"Metabolic Disease","Others","Others","Sodium L-lactate is used as a food additive, preservative, acidity regulator and bulking agent.",113.07,"867-56-1",22,196.32,0,0,"http://www.selleck.cn/products/sodium-l-lactate.html","C3H5NaO3","free base","N/A","[Na+].CC(O)C([O-])=O",-1.867,0,1,1]
["S6011","Acetamide","h10","L1300-26","in 10mM DMSO","DMF, CFDA, NDC","Martindale the Extra Pharmacopoei, EP10.2, USP43-NF38, IP2010",null,"Others","Others","Others","Acetamide (ethanamide, Acetic acid amide) is an organic compound that can be used as a plasticizer and an industrial solvent.",59.07,"60-35-5",11,186.22,0,0,"http://www.selleck.cn/products/acetamide.html","C2H5NO","free base","ethanamide, Acetic acid amide","CC(N)=O",-0.833,1,1,0]
["S6014","Isonicotinic acid","a11","L1300-26","in 10mM DMSO","DMF","USP42-NF37",null,"Others","Others","Others","Isonicotinic acid (Isoniazid, 4-pyridinecarboxylic acid, p-pyridinecarboxylic acid, 4-Picolinic acid) is a metabolite of isoniazid. It is an isomer of nicotinic acid.",123.11,"55-22-1",5,40.61,0,0,"http://www.selleck.cn/products/isonicotinic-acid.html","C6H5NO2","free base","Isoniazid, 4-pyridinecarboxylic acid, p-pyridinecarboxylic acid, 4-Picolinic acid","OC(=O)C1=CC=NC=C1",0.309,2,0,1]
["S6015","Benzylcetyldimethylammonium chloride hydrate","b11","L1300-26","in 10mM DMSO","FDA",null,null,"Infection; Inflammation/Immunology","Others","Others","Benzylcetyldimethylammonium chloride hydrate is a chemical.",396.09,"122-18-9",82,207.02,0,0,"http://www.selleck.cn/products/benzylcetyldimethylammonium-chloride-hydrate.html","C25H46ClN","hydrate","N/A","[Cl-].CCCCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1",4.678,0,0,17]
["S6035","2-Naphthol","c11","L1300-26","in 10mM DMSO",null,"BP2016;USP36-NF31;IP2010",null,"Others","Others","Others","2-Naphthol (2-Hydroxynaphthalene, 2-Naphthalenol, beta-Naphthol, Naphth-2-ol, β-naphthol), a potential antinematodal drug, is a widely used intermediate for the production of dyes and other compounds.",144.17,"135-19-3",28,194.22,0,0,"http://www.selleck.cn/products/2-naphthol.html","C10H8O","free base","2-Hydroxynaphthalene, 2-Naphthalenol, beta-Naphthol, Naphth-2-ol, β-naphthol","OC1=CC=C2C=CC=CC2=C1",2.496,0,1,0]
["S6041","Dibutyl sebacate","d11","L1300-26","in 10mM DMSO",null,"USP42-NF37;Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Dibutyl sebacate is an organic chemical which is mainly used as a plasticizer in the production of plastics.",314.46,"109-43-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/dibutyl-sebacate.html","C18H34O4","free base","N/A","CCCCOC(=O)CCCCCCCCC(=O)OCCCC",5.486,4,0,17]
["S6047","Lactose","e11","L1300-26","in 10mM DMSO","DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.3,KP Ⅹ,Ph.Int_6th,BP2017,JP17,IP2010",null,"Endocrinology/Immunology/Inflammation","Others","Others","Lactose is a disaccharide naturally found in milk and dairy.",342.3,"63-42-3",34,99.33,0,0,"http://www.selleck.cn/products/lactose.html","C12H22O11","free base","N/A","OCC(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)C(O)C=O",-4.538,3,8,8]
["S6049","(+)-(S)-Carvone","f11","L1300-26","in 10mM DMSO",null,"BP2017",null,"Others","Others","Others","(+)-(S)-Carvone, a monoterpene found mainly in caraway and dill seed oils, is used in cosmetic, food and pharmaceutical preparations.",150.22,"2244-16-8","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/s-carvone.html","C10H14O","free base","N/A","CC(=C)C1CC=C(C)C(=O)C1",2.501,1,0,1]
["S6052","Saccharin sodium salt hydrate","g11","L1300-26","in 10mM DMSO","DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,EP9.7,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010",null,"Others","Others","Others","Saccharin (O-Sulfobenzimide, O-Benzoic sulfimide, Saccharimide) is an artificial sweetener with effectively no food energy.",205.17,"82385-42-0",41,199.83,0,0,"http://www.selleck.cn/products/saccharin-sodium-salt-hydrate.html","C7H4NNaO3S.xH2O","hydrate","O-Sulfobenzimide sodium salt hydrate, O-Benzoic sulfimide sodium salt hydrate, Saccharimide sodium salt hydrate","[Na+].O=C1[N-][S](=O)(=O)C2=C1C=CC=C2",1.197,3,0,0]
["S6053","Phenylglyoxylic acid","h11","L1300-26","in 10mM DMSO",null,"USP42-NF37",null,"Others","Others","Others","Phenylglyoxylic acid (Benzoyl formate, Phenylglyoxalic acid, Phenylglyoxylate) is a key building block in the field of chemical synthesis and is widely used to synthesize pharmaceutical intermediates or food additives.",150.13,"611-73-4",30,199.83,0,0,"http://www.selleck.cn/products/phenylglyoxylic-acid.html","C8H6O3","free base","Benzoyl formate, Phenylglyoxalic acid, Phenylglyoxylate","OC(=O)C(=O)C1=CC=CC=C1",1.345,2,0,2]
["S6055","(S)-(−)-Limonene","a2","L1300-27","in 10mM DMSO","CFDA","EP9.2,USP",null,"Cancer/Metabolic Disease","Others","Others","(S)-(−)-Limonene, a fragrance monoterpene mainly found in citrus peel oil, is also naturally occurs in the essential oils of herbs, tea tree oil, and turpentine oil.,",136.23,"5989-54-8","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/limonene.html","C10H16","free base","N/A","CC(=C)C1CCC(=CC1)C",3.502,0,0,1]
["S6058","β-Caryophyllene","b2","L1300-27","in 10mM DMSO",null,"BP2019",null,"Inflammation/Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","β-Caryophyllene is a natural bicyclic sesquiterpene that is a constituent of many essential oils. It acts as a non-steroidal anti-inflammatory drug, a fragrance and a metabolite.",204.35,"87-44-5","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/caryophyllene.html","C15H24","free base","N/A","CC/1=C\\CCC(=C)C2CC(C)(C)C2CC1",4.753,0,0,0]
["S6065","Congo Red","c2","L1300-27","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei, EP10.2, USP43-NF38 , IP2010",null,"Diagnosis","Dyes","Others","Congo Red (Direct Red 28) is an indicator dye that is blue-violet at pH 3.0 and red at pH 5.0. It is an acid dye used in testing for hydrochloric acid in gastric contents but has carcinogenic properties.",696.66,"573-58-0",139,199.52,0,0,"http://www.selleck.cn/products/congo-red.html","C32H22N6Na2O6S2","free base","Direct Red 28","[Na+].[Na+].NC1=C2C=CC=CC2=C(C=C1N=NC3=CC=C(C=C3)C4=CC=C(C=C4)N=NC5=CC(=C6C=CC=CC6=C5N)[S]([O-])(=O)=O)[S]([O-])(=O)=O",2.586,4,2,7]
["S6067","2,4-dichlorobenzyl alcohol","d2","L1300-27","in 10mM DMSO",null,"BP2019;EP9.2",null,"Infection","Antiviral,Bacterial","Microbiology","2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections.",177.03,"1777-82-8",35,197.71,0,0,"http://www.selleck.cn/products/2-4-dichlorobenzyl-alcohol.html","C7H6Cl2O","free base","N/A","OCC1=C(Cl)C=C(Cl)C=C1",2.554,0,1,1]
["S6068","Doxycycline monohydrate","e2","L1300-27","in 10mM DMSO","FDA,DMF,NDC,PMDA,CFDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017","062450,062569,065032,065041,065053,065055,065070,065285,065353,065356,065377,065427,065454,065471,090855,091277,091406,091605,200065,201678,202778,203278,204234,204446,205115,207757,209165,209396,209582","Infection/Parasitology","Antibiotics","Microbiology","Doxycycline is a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity.",462.45,"17086-28-1",47,101.63,0,0,"http://www.selleck.cn/products/doxycycline-monohydrate.html","C22H26N2O9","monohydrate","N/A","O.CC1C2C(O)C3C(N(C)C)C(=C(C(N)=O)C(=O)C3(O)C(=C2C(=O)C4=C1C=CC=C4O)O)O",-0.959,3,5,2]
["S6073","Diclofenac acid","f2","L1300-27","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,IP2010",null,"Inflammation","COX,Immunology & Inflammation related","Immunology & Inflammation","Diclofenac acid is a nonsteroidal anti-inflammatory drug that has analgesic, anti-inflammatory, and antipyretic properties, and has been shown to be effective in treating a variety of acute and chronic pain and inflammatory conditions. It inhibits cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) with relative equipotency.",296.15,"15307-86-5",59,199.22,0,0,"http://www.selleck.cn/products/diclofenac-acid.html","C14H11Cl2NO2","free base","N/A","OC(=O)CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1",4.373,1,1,4]
["S6079","2-Methylhexanoic acid","g2","L1300-27","in 10mM DMSO","DMF",null,null,"Others","Others","Others","2-Methylhexanoic acid is a flavouring ingredient.",130.18,"4536-23-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/2-methylhexanoic-acid.html","C7H14O2","free base","N/A","CCCCC(C)C(O)=O",2.293,1,0,4]
["S6104","(±)-α-Tocopherol","h2","L1300-27","in 10mM DMSO",null,"BP2019",null,"Metabolic Disease","Vitamin","Metabolism","(±)-α-Tocopherol is a biologically active form of vitamin E, which is a lipid-soluble antioxidant that protects cellular membranes from oxidative damage.",430.71,"10191-41-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/tocopherol.html","C29H50O2","free base","N/A","CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=C(C)C(=C(C)C(=C2O1)C)O",10.44,1,1,12]
["S6115","Pyridoxal 5′-phosphate hydrate","a3","L1300-27","in 10mM DMSO","PMDA","USP43-NF38",null,"Others","DNA/RNA Synthesis","DNA Damage/DNA Repair","Pyridoxal 5′-phosphate (pyridoxal phosphate, Vitamin B6 phosphate, PAL-P, PLP), a vitamin B6 phosphate, is a coenzyme in a variety of enzymatic reactions. Pyridoxal 5′-phosphate at concentrations < 0.5 mM inhibits of polymerization deoxynucleoside triphosphate catalysed by variety of DNA polymerases isolated from type C RNA tumor viruses. The combination of Pyridoxal 5′-phosphate and NEIL2 will make NEIL2 completely lose its ability to bind damaged DNA.",247.14,"853645-22-4",10,40.46,0,0,"http://www.selleck.cn/products/pyridoxal-5-phosphate-hydrate.html","C8H10NO6P.xH2O","hydrate","pyridoxal phosphate, Vitamin B6 phosphate, PAL-P, PLP","CC1=NC=C(CO[P](O)(O)=O)C(=C1O)C=O",0.537,3,1,4]
["S6118","Terpinen-4-ol","b3","L1300-27","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Fungal","Microbiology","Terpinen-4-ol, a naturally occurring monoterpene, is the main bioactive component of tea-tree oil and has been shown to have many biological activities such as antifungal properties.,",154.25,"562-74-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/terpinen-4-ol.html","C10H18O","free base","N/A","CC(C)C1(O)CCC(=CC1)C",2.55,0,0,1]
["S6121","Maltotriose","c3","L1300-27","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.2",null,"Others","Others","Others","Maltotriose is a trisaccharide consisting of three glucose molecules linked with α-1,4 glycosidic bonds. It is a common oligosaccharide metabolite found in human urine after maltose ingestion or infusion.",504.44,"1109-28-0",100,198.24,0,0,"http://www.selleck.cn/products/maltotriose.html","C18H32O16","free base","N/A","OCC1OC(OC2C(O)C(O)C(OC2CO)OC3C(O)C(O)C(O)OC3CO)C(O)C(O)C1O",-6.008,5,10,7]
["S6136","(±)-α-Bisabolol","d3","L1300-27","in 10mM DMSO",null,"EP10.4",null,"Cancer","Anti-infection,Immunology & Inflammation related","Immunology & Inflammation","α-bisabolol is a small, plant-derived, oily sesquiterpene alcohol with some anti-inflammatory and even anti-microbial properties.",222.37,"515-69-5","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/bisabolol.html","C15H26O","free base","N/A","CC(C)=CCCC(C)(O)C1CCC(=CC1)C",4.309,0,0,4]
["S6152","Acid Red 27","e3","L1300-27","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei, USP43-NF38",null,"Others","Others","Others","Acid Red 27 (Azorubin S, Amaranth) is a modified red azo dye used as a food dye and to color cosmetics.",604.47,"915-67-3",120,198.52,0,0,"http://www.selleck.cn/products/acid-red-27.html","C20H11N2Na3O10S3","free base","Azorubin S, Amaranth","[Na+].[Na+].[Na+].OC1=C(C=C2C=C(C=CC2=C1N=NC3=C4C=CC=CC4=C(C=C3)[S]([O-])(=O)=O)[S]([O-])(=O)=O)[S]([O-])(=O)=O",-2.962,2,1,5]
["S6172","Brucine sulfate heptahydrate","f3","L1300-27","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Others","GlyR","Transmembrane Transporters","Brucine is an alkaloid that acts as an antagonist at glycine receptors and paralyzes inhibitory neurons.",1013.11,"60583-39-3",202.62,200,0,0,"http://www.selleck.cn/products/brucine-sulfate-heptahydrate.html","C46H68N4O19S","heptahydrate","N/A","O.O.O.O.O.O.O.COC1=CC2=C(C=C1OC)C34CCN5CC6=CCOC7CC(=O)N2C3C7C6CC45.COC8=CC9=C(C=C8OC)C%10%11CCN%12CC%13=CCOC%14CC(=O)N9C%10C%14C%13CC%11%12.O[S](O)(=O)=O",0.168,8,0,4]
["S6173","Amylmetacresol","g3","L1300-27","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Infection","Anti-infection","Microbiology","Amylmetacresol is an antiseptic used to treat infections of the mouth and throat.",178.27,"1300-94-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/amylmetacresol.html","C12H18O","free base","N/A","CCCCCC1=C(O)C=C(C)C=C1",4.385,0,1,4]
["S6188","p-Toluenesulfonic acid monohydrate","h3","L1300-27","in 10mM DMSO","DMF","USP42-NF37",null,"Others","Others","Others","p-Toluenesulfonic acid (4-Methylbenzenesulfonic acid, Tosylic acid, tosic acid, para-toluene) is an extremely strong acidic compound.",190.22,"6192-52-5",38.04,200,0,0,"http://www.selleck.cn/products/p-toluenesulfonic-acid-monohydrate.html","C7H10O4S","monohydrate","4-Methylbenzenesulfonic acid monohydrate, Tosylic acid monohydrate, tosic acid monohydrate, para-toluene sulfonate monohydrate, tosylate monohydrate","O.CC1=CC=C(C=C1)[S](O)(=O)=O",1.441,0,0,1]
["S6189","Acid Yellow 36","a4","L1300-27","in 10mM DMSO",null,"EP10.4, USP43-NF38, IP2010",null,"Others","Others","Others","Acid Yellow 36 (Metanil Yellow) is a dye of the azo class and used as a pH indicator and it has a color change from red to yellow between pH 1.2 and 2.3.",375.38,"587-98-4",25,66.6,0,0,"http://www.selleck.cn/products/acid-yellow-36.html","C18H14N3NaO3S","free base","Metanil Yellow","[Na+].[O-][S](=O)(=O)C1=CC(=CC=C1)N=NC2=CC=C(NC3=CC=CC=C3)C=C2",2.837,2,1,5]
["S6197","Dimethylamine hydrochloride","b4","L1300-27","in 10mM DMSO",null,"BP2017;IP2010",null,"Others","Others","Others","Dimethylamine is a precursor to several industrially significant compounds.",81.54,"506-59-2",16.31,200,0,0,"http://www.selleck.cn/products/dimethylamine-hydrochloride.html","C2H8ClN","hydrochloride","N/A","Cl.CNC",0.166,0,1,0]
["S6202","Butylated hydroxytoluene","c4","L1300-27","in 10mM DMSO","NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP8.8,Ph.Int_6th,BP2017,IP2010",null,"Others","Others","Others","Butylated hydroxytoluene (dibutylhydroxytoluene, Dibutylated hydroxytoluene, AO-29, BHT) is a lipophilic organic compound that is useful for its antioxidant properties.",220.35,"128-37-0",44.07,200,0,0,"http://www.selleck.cn/products/butylated-hydroxytoluene.html","C15H24O","free base","dibutylhydroxytoluene, Dibutylated hydroxytoluene, AO-29, BHT","CC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C",4.875,0,1,2]
["S6207","Levulinic acid","d4","L1300-27","in 10mM DMSO","DMF",null,null,"Others","Others","Others","Levulinic acid (4-oxopentanoic acid, β-Acetylpropionic acid, 3-Acetopropionic acid, γ-ketovaleric acid) is used as a precursor for pharmaceuticals, plasticizers, and various other additives.",116.12,"123-76-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/levulinic-acid.html","C5H8O3","free base","4-oxopentanoic acid, β-Acetylpropionic acid, 3-Acetopropionic acid, γ-ketovaleric acid","CC(=O)CCC(O)=O",-0.259,2,0,3]
["S6210","Ethanolamine hydrochloride","e4","L1300-27","in 10mM DMSO","FDA,DMF,NDC","EP9.2,BP2017","019357","Others","Others","Others","Ethanolamine (2-Aminoethanol) is a viscous, hygroscopic amino alcohol with an ammoniacal odor. It is widely distributed in biological tissue and is a component of lecithin.",97.54,"2002-24-6",19.51,200,0,0,"http://www.selleck.cn/products/ethanolamine-hydrochloride.html","C2H8ClNO","hydrochloride","2-Aminoethanol hydrochloride","Cl.NCCO",-0.805,0,2,1]
["S6215","Phthalic acid","f4","L1300-27","in 10mM DMSO",null,"EP9.2;BP2017;USP36-NF31",null,"Others","Others","Others","Phthalic acid (1,2-Benzenedioic acid) is an aromatic dicarboxylic acid. It is a human xenobiotic metabolite.",166.13,"88-99-3",33.23,200,0,0,"http://www.selleck.cn/products/phthalic-acid.html","C8H6O4","free base","1,2-Benzenedioic acid","OC(=O)C1=CC=CC=C1C(O)=O",1.089,2,0,2]
["S6217","o-Toluic acid","g4","L1300-27","in 10mM DMSO",null,"BP2019",null,"Others","Others","Others","o-Toluic acid (2-methylbenzoic acid, Orthotoluic acid) is an aromatic dicarboxylic acid. It is a human xenobiotic metabolite.",136.15,"118-90-1",27.23,200,0,0,"http://www.selleck.cn/products/o-toluic-acid.html","C8H8O2","free base","2-methylbenzoic acid, Orthotoluic acid","CC1=C(C=CC=C1)C(O)=O",1.946,1,0,1]
["S6218","Sodium lauryl sulfate","h4","L1300-27","in 10mM DMSO","DMF,NDC","KP Ⅹ,JP17,BP2017,USP39-NF34",null,"Others","Others","Others","Sodium lauryl sulfate is an anionic detergent and surfactant found in many personal care products.",288.38,"151-21-3",57.68,200,0,0,"http://www.selleck.cn/products/sodium-lauryl-sulfate.html","C12H25NaO4S","free base","N/A","[Na+].CCCCCCCCCCCCO[S]([O-])(=O)=O",2.165,1,0,12]
["S6221","Methyl cinnamate","a5","L1300-27","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","AMPK,CaMK,Tyrosinase","Proteases","Methyl cinnamate, an active component of Zanthoxylum armatum, is a widely used natural flavor compound with antimicrobial and tyrosinase inhibitor activities. Methyl Cinnamate Inhibits Adipocyte Differentiation via Activation of the CaMKK2--AMPK Pathway in 3T3-L1 Preadipocytes.",162.19,"103-26-4",32.44,200,0,0,"http://www.selleck.cn/products/methyl-cinnamate.html","C10H10O2","free base","N/A","COC(=O)/C=C/C1=CC=CC=C1",2.153,2,0,3]
["S6223","Triethyl citrate","b5","L1300-27","in 10mM DMSO","CFDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010",null,"Others","Others","Others","Triethyl citrate (Ethyl citrate, E1505, Citric acid ethyl ester) is used in pharmaceutical coatings and plastics.",276.28,"77-93-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/triethyl-citrate.html","C12H20O7","free base","Ethyl citrate, E1505, Citric acid ethyl ester","CCOC(=O)CC(O)(CC(=O)OCC)C(=O)OCC",0.404,6,0,11]
["S6231","Methyl nicotinate","c5","L1300-27","in 10mM DMSO","NDC","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017",null,"Others","Others","Others","Methyl nicotinate (methyl pyridine-3-carboxylate) is an ester of methyl alcohol and nicotinic acid. It is a rubefacient.",137.14,"93-60-7",27.43,200,0,0,"http://www.selleck.cn/products/methyl-nicotinate.html","C7H7NO2","free base","methyl pyridine-3-carboxylate","COC(=O)C1=CC=CN=C1",0.534,3,0,2]
["S6232","Methylamine hydrochloride","d5","L1300-27","in 10mM DMSO",null,"EP10.4, USP43-NF38",null,"Others","Others","Others","Methylamine is used as a building block for the synthesis of many other commercially available compounds.",67.52,"593-51-1",13.5,200,0,0,"http://www.selleck.cn/products/methylamine-hydrochloride.html","CH6ClN","hydrochloride","N/A","Cl.CN",-0.266,0,1,0]
["S6233","Tartaric acid","e5","L1300-27","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,IP2010","018509","Others","Others","Others","Tartaric acid (2,3-Dihydroxysuccinic acid, Threaric acid, Racemic acid, Uvic acid, Paratartaric acid, Winestone) is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes. It has several applications for industrial and pharmaceutical use.",150.09,"87-69-4",30.02,200,0,0,"http://www.selleck.cn/products/tartaric-acid.html","C4H6O6","free base","2,3-Dihydroxysuccinic acid; Threaric acid; Racemic acid; Uvic acid; Paratartaric acid; Winestone","OC(C(O)C(O)=O)C(O)=O",-1.664,2,2,3]
["S6234","Pentadecanoic acid","f5","L1300-27","in 10mM DMSO","DMF",null,null,"Others","Others","Others","Pentadecanoic acid is a saturated fatty acid of exogenous (primarily ruminant) origin. It also has a role as a plant metabolite, a food component, a Daphnia magna metabolite, a human blood serum metabolite and an algal metabolite.",242.4,"1002-84-2",48.48,200,0,0,"http://www.selleck.cn/products/pentadecanoic-acid.html","C15H30O2","free base","N/A","CCCCCCCCCCCCCCC(O)=O",5.936,1,0,13]
["S6235","Sodium dehydroacetate","g5","L1300-27","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP39-NF34",null,"Infection","Bacterial","Microbiology","Sodium dehydroacetate is the sodium salt of dehydroacetic acid, a fungicide and bactericide that is commonly used as a food preservative. Sodium dehydroacetate is a preservative that is used in the formulation of cosmetics and personal care products in order to extend the shelf-life by preventing microbial contamination.",190.13,"4418-26-2",38.03,200,0,0,"http://www.selleck.cn/products/sodium-dehydroacetate.html","C8H7NaO4","free base","N/A","[Na+].CC(=O)C1=C([O-])C=C(C)OC1=O",-0.714,3,0,1]
["S6250","L-Lactic acid","h5","L1300-27","in 10mM DMSO","DMF,NDC","JP17",null,"Others","Others","Others","L-Lactic acid is a natural product that is used as a food additive.,",90.08,"79-33-4","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/l-lactic-acid.html","C3H6O3","free base","N/A","CC(O)C(O)=O",-0.393,1,1,1]
["S6251","Terephthalic acid","a6","L1300-27","in 10mM DMSO","DMF",null,null,"Others","Others","Others","Terephthalic acid (para-Phthalic acid, 1,4-Benzenedioic acid), a raw material for polyethylene terephthalate (PET) production, is one of the most important chemicals in petrochemical industry.",166.13,"100-21-0",33.23,200,0,0,"http://www.selleck.cn/products/terephthalic-acid.html","C8H6O4","free base","para-Phthalic acid; 1,4-Benzenedioic acid","OC(=O)C1=CC=C(C=C1)C(O)=O",1.089,2,0,2]
["S6257","N-Acetylglucosamine","b6","L1300-27","in 10mM DMSO","NDC","USP42-NF37,EP9.2,BP2017",null,"Inflammation","Others","Others","N-Acetylglucosamine (GlcNAc) is a monosaccharide that usually polymerizes linearly through (1,4)-β-linkages. It may be helpful for the treatment of autoimmune diseases.",221.21,"7512-17-6",44.24,200,0,0,"http://www.selleck.cn/products/n-acetylglucosamine.html","C8H15NO6","free base","GlcNAc","CC(=O)NC(C=O)C(O)C(O)C(O)CO",-3.059,2,5,6]
["S6258","1,2-Propanediol","c6","L1300-27","in 10mM DMSO","DMF","IP2010",null,"Ophthalmology","Others","Others","1,2-Propanediol (1,2-Dihydroxypropane, Propylene glycol, Methyl ethyl glycol) is a synthetic liquid substance that is commonly used as an excipient in a variety of drugs and it is also authorised in food products and cosmetics.",76.09,"57-55-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/propanediol.html","C3H8O2","free base","1,2-Dihydroxypropane, Propylene glycol, Methyl ethyl glycol","CC(O)CO",-0.52,0,2,1]
["S6262","Ammonium formate","d6","L1300-27","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.2",null,"Others","Others","Others","Ammonium Formate is the ammonium salt of formic acid. It is widely used in various organic reactions.",63.06,"540-69-2",12.61,200,0,0,"http://www.selleck.cn/products/ammonium-formate.html","CH5NO2","free base","N/A","NOC=O",-0.942,1,1,1]
["S6264","Rutin hydrate","e6","L1300-27","in 10mM DMSO","CFDA,DMF,NDC","CP2005,EP7.0,BP2017,USP39-NF34",null,"Endocrinology/Hematology","Others","Others","Rutin (Quercetin-3-O-rutinoside, Rutoside, Sophorin) is a glycoside found in a wide variety of plants including citrus fruit.",610.52,"207671-50-9",122.1,200,0,0,"http://www.selleck.cn/products/rutin-hydrate.html","C27H30O16.xH2O","free base","Quercetin-3-O-rutinoside, Rutoside, Sophorin","CC1OC(OCC2OC(OC3=C(OC4=C(C(=CC(=C4)O)O)C3=O)C5=CC(=C(O)C=C5)O)C(O)C(O)C2O)C(O)C(O)C1O",-0.424,6,10,6]
["S6272","Glycolic acid","f6","L1300-27","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37",null,"Others","Tyrosinase","Proteases","Glycolic acid (dicarbonous acid, hydroxyacetic acid, hydroacetic acid) is the smallest alpha-hydroxy acid. Due to its excellent capability to penetrate skin, glycolic acid is often used in skin care products, most often as a chemical peel. Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.",76.05,"79-14-1",15.21,200,0,0,"http://www.selleck.cn/products/glycolic-acid.html","C2H4O3","free base","dicarbonous acid, hydroxyacetic acid, hydroacetic acid","OCC(O)=O",-0.877,1,1,1]
["S6275","(−)-β-Pinene","g6","L1300-27","in 10mM DMSO","CFDA","BP2013",null,"Others","Others","Others","(−)-β-Pinene (Nopinene) is a natural organic compound in various plants. It is lethal to S. littoralis third instar larvae (LD50 = 65 μg/larva), inhibits infectious bronchitis virus (IBV) replication (IC50 = 1.32 mM) and exhibits a cytotoxic concentration (CC50) value of greater than 10 mM in Vero cells.",136.23,"18172-67-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/pinene.html","C10H16","free base","Nopinene","CC1(C)C2CCC(=C)C1C2",2.926,0,0,0]
["S6281","Sodium Thiocyanate","h6","L1300-27","in 10mM DMSO","DMF","USP42-NF37,EP9.1,BP2017",null,"Inflammation","Interleukins,ROS","Immunology & Inflammation","Sodium Thiocyanate (NaSCN, Sodium rhodanide, Sodium sulfocyanate, Sodium rhodanate), one of the main sources of the thiocyanate anion, is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals. Sodium thiocyanate (NaSCN) reduces IL-6, whereas increases IL-10 levels. Sodium thiocyanate also reduces ROS.",81.07,"540-72-7",16.21,200,0,0,"http://www.selleck.cn/products/sodium-thiocyanate.html","CNNaS","free base","Sodium rhodanide, Sodium sulfocyanate, Sodium rhodanate","[Na]SC#N",0.625,0,0,0]
["S6284","Tetraethylammonium bromide","a7","L1300-27","in 10mM DMSO",null,"USP36-NF31",null,"Others","Potassium Channel","Transmembrane Transporters","Tetraethylammonium bromide (TEAB, TEA bromide) is used as the source of tetraethylammonium ions in pharmacological and physiological studies, but is also used in organic chemical synthesis. It blocks selective potassium channels.",210.16,"71-91-0",42.03,200,0,0,"http://www.selleck.cn/products/tetraethylammonium-bromide.html","C8H20BrN","bromide","TEAB, TEA bromide","[Br-].CC[N+](CC)(CC)CC",-2.058,0,0,4]
["S6288","Chlorhexidine diacetate","b7","L1300-27","in 10mM DMSO","DMF,NDC,HMA","EP9.4,Ph.Int_6th,BP2015,IP2010",null,"Infection","Anti-infection","Microbiology","Chlorhexidine diacetate (Hibitane diacetate) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.",625.55,"56-95-1",125.11,200,0,0,"http://www.selleck.cn/products/chlorhexidine-diacetate.html","C26H38Cl2N10O4","diacetate","Hibitane diacetate","CC(O)=O.CC(O)=O.ClC1=CC=C(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC2=CC=C(Cl)C=C2)C=C1",3.964,2,6,17]
["S6296","Octanoic acid","c7","L1300-27","in 10mM DMSO",null,"BP2019;IP2010;Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Octanoic acid (caprylic acid) is found naturally in the milk of various mammals, and as a minor constituent of coconut oil and palm kernel oil. It is used in the production of esters used in perfumery and also in the manufacture of dyes.",144.21,"124-07-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/octanoic-acid.html","C8H16O2","free base","caprylic acid","CCCCCCCC(O)=O",2.743,1,0,6]
["S6316","N-Acetyl-L-tyrosine","d7","L1300-27","in 10mM DMSO","CFDA,DMF",null,null,"Others","Others","Others","N-Acetyl-L-tyrosine is an acetylated form of the amino acid, L-Tyrosine. It is involved in catecholamine production.",223.23,"537-55-3",44.65,200,0,0,"http://www.selleck.cn/products/n-acetyl-l-tyrosine.html","C11H13NO4","free base","N/A","CC(=O)NC(CC1=CC=C(O)C=C1)C(O)=O",0.653,2,2,4]
["S6324","5-Methoxytryptamine","e7","L1300-27","in 10mM DMSO","NDC",null,null,"Others","5-HT Receptor","Neuronal Signaling","5-Methoxytryptamine (Mexamine, Methoxytryptamine) is a tryptamine derivative that acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors.",190.24,"608-07-1",38.05,200,0,0,"http://www.selleck.cn/products/5-methoxytryptamine.html","C11H14N2O","free base","Mexamine, Methoxytryptamine","COC1=CC2=C([NH]C=C2CCN)C=C1",1.534,1,2,3]
["S6335","Ethyl maltol","f7","L1300-27","in 10mM DMSO",null,"USP43-NF38",null,"Others","Others","Others","Ethyl maltol (2-Ethyl-3-hydroxy-4H-pyran-4-one, 2-Ethyl pyromeconic acid) is a common flavourant in some confectioneries.",140.14,"4940-11-8",28.03,200,0,0,"http://www.selleck.cn/products/ethyl-maltol.html","C7H8O3","free base","2-Ethyl-3-hydroxy-4H-pyran-4-one, 2-Ethyl pyromeconic acid","CCC1=C(O)C(=O)C=CO1",0.301,2,1,1]
["S6342","Glycerol Tri-n-octanoate","g7","L1300-27","in 10mM DMSO","DMF",null,null,"Neurological Disease","Others","Others","Glycerol Tri-n-octanoate (Glycerol trioctanoate, Glycerol tricaprylate, Trioctanoin, Tricaprylin) is a well-known raw material largely used in cosmetic products.",470.68,"538-23-8","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/glycerol-tri-n-octanoate.html","C27H50O6","free base","Glycerol trioctanoate, Glycerol tricaprylate, Trioctanoin, Tricaprylin","CCCCCCCC(=O)OCC(COC(=O)CCCCCCC)OC(=O)CCCCCCC",8.572,6,0,26]
["S6343","D-Glucuronic acid","h7","L1300-27","in 10mM DMSO",null,"BP2018;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","D-Glucuronic acid (D-Glucopyranuronic Acid) is a key intermediate metabolite of the uronic acid pathway and may plays a role in the detoxification of certain drugs.",194.14,"6556-12-3",38.83,200,0,0,"http://www.selleck.cn/products/d-glucuronic-acid.html","C6H10O7","free base","D-Glucopyranuronic Acid","OC(C=O)C(O)C(O)C(O)C(O)=O",-2.664,2,4,5]
["S6346","L-(+)-Arabinose","a8","L1300-27","in 10mM DMSO",null,"BP2019;EP9.2",null,"Metabolic Disease","Others","Others","L-(+)-Arabinose (DL-Arabinose, Pectinose) is used as a substrate to identify, differentiate and characterize pentose sugar isomerase(s).",150.13,"5328-37-0",30.03,200,0,0,"https://www.selleckchem.com/products/l--arabinose.html","C5H10O5","free base","DL-Arabinose, Pectinose","OCC(O)C(O)C(O)C=O",-2.28,1,4,4]
["S6400","Glucosamine","b8","L1300-27","in 10mM DMSO","CFDA,DMF,HMA","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,BP2017",null,"Inflammation","HIF","Angiogenesis","Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine（GS） treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites.",179.17,"3416-24-8",23,128.37,36,200.93,"http://www.selleck.cn/products/glucosamine.html","C6H13NO5","Free Base","2-amino-2-deoxy-D-glucose","NC(C=O)C(O)C(O)C(O)CO",-3.081,1,5,5]
["S6402","2-Aminoethanethiol","c8","L1300-27","in 10mM DMSO","FDA,DMF,NDC,PMDA",null,"020392;200740","Metabolic Disease","Others","Others","2-Aminoethanethiol (cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Thioethanolamine, Mercaptamine) is a radiation-protective agent that oxidizes in air to form cystamine.",77.15,"60-23-1",15,194.43,15,194.43,"http://www.selleck.cn/products/2-aminoethanethiol.html","C2H7NS","Free Base","cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Decarboxycysteine, Thioethanolamine, Mercaptamine","NCCS",-0.216,0,1,1]
["S6403","Chloramine-T","d8","L1300-27","in 10mM DMSO",null,"EP8.8;BP2019",null,"Others","Others","Others","Chloramine-T is a N-chlorinated and N-deprotonated sulfonamide used as a biocide and a mild disinfectant.",227.64,"127-65-1",46,202.07,46,202.07,"http://www.selleck.cn/products/chloramine-t.html","C7H7ClNNaO2S","Free Base","N/A","CC1=CC=C(C=C1)[S](=O)(=O)N([Na])Cl",1.714,2,0,2]
["S6404","Salicylamide","e8","L1300-27","in 10mM DMSO","NDC","Martindale the Extra Pharmacopoei,USP42-NF37",null,"Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Salicylamide (o-hydroxybenzamide) is a non-prescription drug with analgesic and antipyretic properties.",137.14,"65-45-2",27,196.88,"˂1",0,"http://www.selleck.cn/products/salicylamide.html","C7H7NO2","Free Base","o-hydroxybenzamide","NC(=O)C1=C(O)C=CC=C1",0.59,1,2,1]
["S6405","Octisalate","f8","L1300-27","in 10mM DMSO","NDC","Martindale the Extra Pharmacopoei,USP42-NF37",null,"Others","Others","Others","Octisalate (Ethylhexyl Salicylate, Octyl salicylate) is an organic compound used as an ingredient in sunscreens and cosmetics to absorb UVB (ultraviolet) rays from the sun.",250.33,"118-60-5","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/octisalate.html","C15H22O3","Free Base","Ethylhexyl Salicylate, Octyl salicylate","CCCCC(CC)COC(=O)C1=C(O)C=CC=C1",4.46,2,1,8]
["S6407","Tulobuterol hydrochloride","g8","L1300-27","in 10mM DMSO","CFDA,PMDA","Martindale the Extra Pharmacopoei,KP Ⅹ,JP17",null,"Inflammation/Respiratory Disease","Androgen Receptor","Neuronal Signaling","Tulobuterol is a long-acting β2-adrenergic receptor agonist that has bronchodilatory, anti-inflammatory, and antiviral activities.",264.19,"56776-01-3",53,200.61,53,200.61,"http://www.selleck.cn/products/tulobuterol-hydrochloride.html","C12H19Cl2NO","hydrochloride","N/A","Cl.CC(C)(C)NCC(O)C1=C(Cl)C=CC=C1",2.834,0,2,4]
["S6408","Hexetidine","h8","L1300-27","in 10mM DMSO","DMF","Martindale the Extra Pharmacopoei,EP8.8,EP9.2,BP2017",null,"Infection","Fungal","Microbiology","Hexetidine is an anti-bacterial and anti-fungal agent with local anesthetic, astringent, deodorant and antiplaque activity.",339.6,"141-94-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/hexetidine.html","C21H45N3","Free Base","N/A","CCCCC(CC)CN1CN(CC(CC)CCCC)CC(C)(N)C1",5.697,0,1,12]
["S6409","Zucapsaicin","a9","L1300-27","in 10mM DMSO","marketed in Canada",null,null,"Inflammation","TRP Channel","Transmembrane Transporters","Zucapsaicin, the cis-isomer of capsaicin, is a topical analgesic used to treat osteoarthritis of the knee and other neuropathic pain. It is also a TRPV-1 modulator.",305.41,"25775-90-0",61,199.73,"<1",0,"http://www.selleck.cn/products/zucapsaicin.html","C18H27NO3","Free Base","N/A","COC1=C(O)C=CC(=C1)CNC(=O)CCCC\\C=C/C(C)C",3.91,2,2,9]
["S6410","Clemizole","b9","L1300-27","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Infection","Dopamine Receptor,TRP Channel","Neuronal Signaling","Clemizole, a first-generation histamine receptor (H1) antagonist, is a potent inhibitor of behavioural and electrographic seizure activity. It has a potential therapeutic effect on hepatitis C infection and also potently inhibits TRPC5 ion channels.",325.84,"442-52-4",65,199.48,-1,0,"http://www.selleck.cn/products/clemizole.html","C19H20ClN3","Free Base","N/A","ClC1=CC=C(C[N]2C(=NC3=C2C=CC=C3)CN4CCCC4)C=C1",4.527,1,0,4]
["S6411","Nimorazole","c9","L1300-27","in 10mM DMSO","DMF","Martindale the Extra Pharmacopoei",null,"Cancer","Bacterial","Microbiology","Nimorazole is a water soluble, 5-nitroimidazole compound with antibacterial and potential radiosensitizing activity.",226.23,"6506-37-2",45,198.91,-1,0,"http://www.selleck.cn/products/nimorazole.html","C9H14N4O3","Free Base","N/A","[O-][N+](=O)C1=CN=C[N]1CCN2CCOCC2",-0.232,2,0,4]
["S6421","Diroximel Fumarate","d9","L1300-27","in 10mM DMSO","FDA, DMF, NDC",null,211855,"Neurological Disease","Others","Others","Diroximel Fumarate (ALKS-8700) is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body.",255.22,"1577222-14-0",51,199.83,-1,0,"http://www.selleck.cn/products/diroximel-fumarete.html","C11H13NO6","Fumarete","ALKS-8700","COC(=O)\\C=C\\C(=O)OCCN1C(=O)CCC1=O",-0.278,6,0,7]
["S6432","Cevimeline HCl hemihydrate","e9","L1300-27","in 10mM DMSO","FAD,DMF,NDC,PMDA","Martindale the Extra Pharmacopoei","091260,091591,203775,204746","Others","AChR","Metabolism","Cevimeline HCl hemihydrate(AF 102B, SNI 2011, SNK 508) is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3.",244.78,"153504-70-2",40,169.66,40,169.66,"https://www.selleckchem.com/products/cevimeline.html","C10H18ClNOS.1/2H2O","HCl hemihydrate","AF 102B, SNI 2011, SNK 508","Cl.CC1OC2(CS1)CN3CCC2CC3",2.151,1,0,0]
["S6433","Udenafil","f9","L1300-27","in 10mM DMSO","DMF","Martindale the Extra Pharmacopoei",null,"Cardiovascular Disease","PDE","Metabolism","Udenafil is a potent antagonist of human PDE5 with an IC50 of 8.25 nM and a comparable selectivity profile as sildenafil for the other PDEs.",516.66,"268203-93-6",100,193.55,"<1",0,"http://www.selleck.cn/products/udenafil.html","C25H36N6O4S","Free Base","N/A","CCCOC1=CC=C(C=C1C2=NC(=O)C3=C(N2)C(=N[N]3C)CCC)[S](=O)(=O)NCCC4CCCN4C",3.298,6,2,11]
["S6435","Mequitazine","g9","L1300-27","in 10mM DMSO","PMDA","Martindale the Extra Pharmacopoei,KP Ⅹ,JP17",null,"Immunology/Inflammation","Histamine Receptor","Neuronal Signaling","Mequitazine (LM-209) is a histamine H1 antagonist which competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract.",322.47,"29216-28-2",32,99.23,"<1",0,"http://www.selleck.cn/products/mequitazine.html","C20H22N2S","Free Base","LM-209","C1CN2CCC1C(C2)CN3C4=C(SC5=C3C=CC=C5)C=CC=C4",4.409,0,0,2]
["S6439","Talniflumate","h9","L1300-27","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Immunology/Inflammation","Chloride Channel,Immunology & Inflammation related","Immunology & Inflammation","Talniflumate (MSI-1995) is an anti-inflammatory molecule studied and used as a mucin regulator in the treatment of cystic fibrosis, chronic obstructive pulmonary disease (COPD) and asthma. Talniflumate is also an inhibitor of human calcium-activated chloride channels.",414.33,"66898-62-2",61,147.23,"<1",0,"http://www.selleck.cn/products/talniflumate.html","C21H13F3N2O4","Free Base","MSI-1995","FC(F)(F)C1=CC(=CC=C1)NC2=C(C=CC=N2)C(=O)OC3OC(=O)C4=C3C=CC=C4",5.023,5,1,6]
["S6440","Halazone","a10","L1300-27","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei,USP42-NF37",null,"Others","Others","Others","Halazone (Pantocide, p-sulfondichloramidobenzoic acid) is widely used to disinfect drinking water.",270.09,"80-13-7",54,199.93,"<1",0,"http://www.selleck.cn/products/halazone.html","C7H5Cl2NO4S","Free Base","Pantocide, p-sulfondichloramidobenzoic acid","OC(=O)C1=CC=C(C=C1)[S](=O)(=O)N(Cl)Cl",1.343,3,0,3]
["S6441","Riboflavin Tetrabutyrate","b10","L1300-27","in 10mM DMSO","CFDA,NDC",null,null,"Others","Others","Others","Riboflavin tetrabutyrate is a lipophilic flavin derivative with antioxidative and lipid peroxide-removing activity.",656.72,"752-56-7",100,152.27,"<1",0,"http://www.selleck.cn/products/riboflavin-tetrabutyrate.html","C33H44N4O10","Tetrabutyrate","N/A","CCCC(=O)OCC(OC(=O)CCC)C(OC(=O)CCC)C(CN1C2=C(C=C(C)C(=C2)C)N=C3C(=O)NC(=O)N=C13)OC(=O)CCC",5.754,12,1,21]
["S6442","Chlorphenesin","c10","L1300-27","in 10mM DMSO","FDA,DMF,PMDA","Martindale the Extra Pharmacopoei,KP Ⅹ,JP17","014217","Neurological Disease","Anti-infection","Microbiology","Chlorphenesin is a synthetic preservative used in skin care as a cosmetic biocide.",202.63,"104-29-0",41,202.34,10,49.35,"http://www.selleck.cn/products/chlorphenesin.html","C9H11ClO3","Free Base","N/A","OCC(O)COC1=CC=C(Cl)C=C1",1.427,1,2,4]
["S6443","Chromium picolinate","d10","L1300-27","in 10mM DMSO","DMF ,NDC","USP42-NF37",null,"Metabolic Disease","IGF-1R","Protein Tyrosine Kinase","Chromium picolinate is a coordination complex consisting of chromium(III) and picolinic acid. It is used as a nutritional supplement for optimal insulin function in patients with Type 2 diabetes or promotion of weight loss.",418.3,"14639-25-9",5,11.95,"<1",0,"http://www.selleck.cn/products/chromium-picolinate.html","C18H12CrN3O6","Free Base","N/A","[Cr+3]|1|2|3(|[O-]C(=O)C4=N|1C=CC=C4)(|[O-]C(=O)C5=N|2C=CC=C5)|[O-]C(=O)C6=N|3C=CC=C6",-1.647,0,0,0]
["S6444","Triclocarban","e10","L1300-27","in 10mM DMSO","DMF ,NDC","Martindale the Extra Pharmacopoei,USP42-NF37",null,"Others","Bacterial","Microbiology","Triclocarban is an antibacterial agent common used in personal care products.",315.58,"101-20-2",63,199.63,"<1",0,"http://www.selleck.cn/products/triclocarban.html","C13H9Cl3N2O","Free Base","N/A","ClC1=CC=C(NC(=O)NC2=CC=C(Cl)C(=C2)Cl)C=C1",4.516,1,2,2]
["S6447","Carazolol","f10","L1300-27","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Carazolol is a non-specific β-adrenergic receptor blocking agent and binds to β receptors irreversibly.",298.38,"57775-29-8",60,201.09,"<1",0,"http://www.selleck.cn/products/carazolol.html","C18H22N2O2","Free Base","N/A","CC(C)NCC(O)COC1=CC=CC2=C1C3=C([NH]2)C=CC=C3",3.125,1,3,6]
["S6448","Ibuprofen piconol","g10","L1300-27","in 10mM DMSO","PMDA","JP17",null,"Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Ibuprofen piconol (U75630) is a non-steroidal, anti-inflammatory (NSAID) drug for the topical relief of primary thermal burns and sunburns.",297.39,"64622-45-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/ibuprofen-piconol.html","C19H23NO2","Free Base","U75630","CC(C)CC1=CC=C(C=C1)C(C)C(=O)OCC2=NC=CC=C2",4.481,3,0,7]
["S6450","Apronal","h10","L1300-27","in 10mM DMSO","marketed in Japan",null,null,"Neurological Disease","Others","Others","Apronal (Apronalide, Allylisopropylacetylurea, Allylisopropylacetylcarbamide) is a hypnotic/sedative drug.",184.24,"528-92-7",37,200.83,"<1",0,"http://www.selleck.cn/products/apronal.html","C9H16N2O2","Free Base","Apronalide, Allylisopropylacetylurea, Allylisopropylacetylcarbamide","CC(C)C(CC=C)C(=O)NC(N)=O",1.306,2,2,4]
["S6452","Delavirdine mesylate","a11","L1300-27","in 10mM DMSO","FDA,NDC","Martindale the Extra Pharmacopoei","020705","Infection","Reverse Transcriptase","Microbiology","Delavirdine Mesylate(U 90152 mesylate) is a mesylate salt form of delavirdine, which is a synthetic, non-nucleoside reverse transcriptase inhibitor.",552.67,"147221-93-0",100,180.94,"<1",0,"http://www.selleck.cn/products/delavirdine.html","C23H32N6O6S2","mesylate","U 90152 mesylate","CC(C)NC1=CC=CN=C1N2CCN(CC2)C(=O)C3=CC4=C([NH]3)C=CC(=C4)N[S](C)(=O)=O.C[S](O)(=O)=O",1.879,4,3,6]
["S6453","Bicyclol","b11","L1300-27","in 10mM DMSO","CFDA","Martindale the Extra Pharmacopoei",null,"Infection","HBV","Microbiology","Bicyclol (SY-801) is a drug that can improve liver function and inhibit HBV replication.",390.34,"118159-48-1",78,199.83,"<1",0,"http://www.selleck.cn/products/bicyclol.html","C19H18O9","Free Base","SY-801","COC(=O)C1=CC(=C2OCOC2=C1C3=C4OCOC4=C(OC)C=C3CO)OC",2.102,8,1,6]
["S6454","Docosahexaenoic Acid","c11","L1300-27","in 10mM DMSO","NDC","Martindale the Extra Pharmacopoei,USP32-NF27",null,"Nutritional support","Others","Others","Docosahexaenoic Acid (DHA, Cervonic acid, Doconexent) is essential for the growth and functional development of the brain in infants. DHA is also required for maintenance of normal brain function in adults.",328.49,"6217-54-5",66,200.92,8,24.35,"http://www.selleck.cn/products/docosahexaenoic-acid.html","C22H32O2","Free Base","DHA, Cervonic acid, Doconexent","CC\\C=C/C/C=C\\C\\C=C/C/C=C\\C\\C=C/C/C=C\\CCC(O)=O",6.462,1,0,14]
["S6455","Clebopride malate","d11","L1300-27","in 10mM DMSO","CFDA","Martindale the Extra Pharmacopoei,EP8.8,KP Ⅹ,JP17,BP2017",null,"Gastroenterology","Dopamine Receptor","Neuronal Signaling","Clebopride is a dopamine antagonist drug and is used to treat functional gastrointestinal disorder such as nausea or vomiting.",507.96,"57645-91-7",100,196.87,33,64.97,"http://www.selleck.cn/products/clebopride.html","C24H30ClN3O7","malate","N/A","COC1=C(C=C(Cl)C(=C1)N)C(=O)NC2CC[NH+](CC2)CC3=CC=CC=C3.OC(CC(O)=O)C([O-])=O",-1.413,3,3,8]
["S6456","Glycyrrhetinic acid","e11","L1300-27","in 10mM DMSO","CFDA,PMDA","BP2016,IP2010",null,"Endocrinology","Others","Others","Glycyrrhetinic acid is a triterpenoid aglycone component of the natural product glycyrrhizinic acid and possesses remarkable anti-proliferative and apoptosis-inducing activity in various cancer cell lines.",470.68,"1449-05-4",94,199.71,"<1",0,"http://www.selleck.cn/products/glycyrrhetinic-acid.html","C30H46O4","Free Base","N/A","CC1(C)C(O)CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O",5.656,2,1,1]
["S6457","Flurbiprofen Axetil","f11","L1300-27","in 10mM DMSO","CFDA",null,null,"Inflammation","COX","Immunology & Inflammation","Flurbiprofen Axetil is one of the commonly used nonsteroidal anti-inflammatory drugs (NSAIDs) that nonselectively inhibits cyclooxygenase.",330.35,"91503-79-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleck.cn/products/flurbiprofen-axetil.html","C19H19FO4","Free Base","N/A","CC(OC(C)=O)OC(=O)C(C)C1=CC=C(C(=C1)F)C2=CC=CC=C2",3.906,4,0,7]
["S6459","Nifurtimox","g11","L1300-27","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei,Ph.Int_6th",null,"Cancer/Infection/Parasite","Anti-infection","Microbiology","Nifurtimox (BAY-2502) is an antiprotozoal agent.",287.29,"23256-30-6",57,198.41,"<1",0,"http://www.selleck.cn/products/nifurtimox.html","C10H13N3O5S","Free Base","BAY-2502","CC1C[S](=O)(=O)CCN1\\N=C\\C2=CC=C(O2)[N+]([O-])=O",0.772,4,0,3]
["S6461","Permethrin","h11","L1300-27","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale the Extra Pharmacopoei,EP8.8,BP2017","074806,075014,076090,076369,211303","Others","Anti-infection","Microbiology","Permethrin(NRDC-143) is a synthetic Type I pyrethroidal neurotoxic pesticide that has been responsible for accidental animal deaths.",391.29,"52645-53-1",78,199.34,"<1",0,"http://www.selleck.cn/products/permethrin.html","C21H20Cl2O3","Free Base","NRDC-143","CC1(C)C(C=C(Cl)Cl)C1C(=O)OCC2=CC(=CC=C2)OC3=CC=CC=C3",5.438,3,0,7]
["S6462","Amezinium (methylsulfate)","a2","L1300-28","in 10mM DMSO","PMDA","Martindale the Extra Pharmacopoei",null,"Others","MAO","Neuronal Signaling","Amezinium is a sympathomimetic used for its vasopressor effects in the treatment of hypotensive states. It is a MAO inhibitor, antagonizes the response to tyramine and blocks neuronal uptake of noradrenaline.",313.33,"30578-37-1",63,201.07,32,102.13,"http://www.selleck.cn/products/amezinium.html","C12H15N3O5S","methylsulfate","N/A","COC1=[N+](N=CC(=C1)N)C2=CC=CC=C2.CO[S]([O-])(=O)=O",-1.09,3,1,3]
["S6465","Tafamidis","b2","L1300-28","in 10mM DMSO","FDA,EMA",null,212161,"Others","5-HT Receptor","Neuronal Signaling","Tafamidis is a kinetic stabilizer of transthyretin (TTR) that prevents amyloidogenesis by wild-type and mutant TTRs.",308.12,"594839-88-0",31,100.61,"<1",0,"http://www.selleck.cn/products/tafamidis.html","C14H7Cl2NO3","Free Base","N/A","OC(=O)C1=CC=C2N=C(OC2=C1)C3=CC(=CC(=C3)Cl)Cl",4.239,3,0,2]
["S6467","Fosfluconazole","c2","L1300-28","in 10mM DMSO","PMDA","Martindale the Extra Pharmacopoei",null,"Infection","Fungal","Microbiology","Fosfluconazole is a water-soluble phosphate prodrug of fluconazole, which is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.",386.25,"194798-83-9",19,49.19,"<1",0,"http://www.selleck.cn/products/fosfluconazole.html","C13H13F2N6O4P","Free Base","N/A","O[P](O)(=O)OC(C[N]1C=NC=N1)(C[N]2C=NC=N2)C3=C(F)C=C(F)C=C3",0.678,5,0,7]
["S6468","Trandolapril","d2","L1300-28","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,BP2017,IP2010","077256,077307,077489,077522,077805,078320,078346,078438,078493,078508","Cardiovascular Disease","ACE,RAAS","Endocrinology & Hormones","Trandolapril(RU44570) is a newly developed angiotensin-converting enzyme (ACE) inhibitor that is rapidly hydrolyzed mainly in the liver to its biologically active metabolite trandolaprilat.",430.54,"87679-37-6",86,199.75,"<1",0,"http://www.selleck.cn/products/trandolapril.html","C24H34N2O5","Free Base","RU44570","CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCCC3CC2C(O)=O",0.764,4,1,10]
["S6469","Thonzylamine","e2","L1300-28","in 10mM DMSO","NDC","Martindale the Extra Pharmacopoei",null,"Immunology","AChR,Histamine Receptor","Neuronal Signaling","Thonzylamine (Neohetramine) is an antihistamine and anticholinergic drug.",286.37,"91-85-0",57,199.04,57,199.04,"http://www.selleck.cn/products/thonzylamine.html","C16H22N4O","Free Base","Neohetramine","COC1=CC=C(CN(CCN(C)C)C2=NC=CC=N2)C=C1",2.44,3,0,7]
["S6470","Fluralaner","f2","L1300-28","in 10mM DMSO","CFDA",null,null,"Parasite","Chloride Channel,GABA Receptor","Neuronal Signaling","Fluralaner (A1443, AH252723) is a systemic insecticide and acaricide that is administered orally.Fluralaner inhibits γ-aminobutyric acid (GABA)-gated chloride channels (GABAA receptors) and L-glutamate-gated chloride channels (GluCls)",556.29,"864731-61-3",100,179.76,"<1",0,"http://www.selleck.cn/products/fluralaner.html","C22H17Cl2F6N3O3","Free Base","A1443, AH252723","CC1=CC(=CC=C1C(=O)NCC(=O)NCC(F)(F)F)C2=NOC(C2)(C3=CC(=CC(=C3)Cl)Cl)C(F)(F)F",5.176,4,2,8]
["S6472","Tinoridine hydrochloride","g2","L1300-28","in 10mM DMSO","marketed in Japan and France",null,null,"Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Tinoridine hydrochloride (Y-3642) is a non-steroidal anti-inflammatory drug with a potent antiperoxidative activity.",352.88,"25913-34-2",18,51.01,"<1",0,"http://www.selleck.cn/products/tinoridine-hydrochloride.html","C17H21ClN2O2S","hydrochloride","Y-3642 HCl","Cl.CCOC(=O)C1=C(N)SC2=C1CCN(CC3=CC=CC=C3)C2",3.265,2,1,5]
["S6473","Pinaverium bromide","h2","L1300-28","in 10mM DMSO","CFDA,DMF","Martindale the Extra Pharmacopoei",null,"Gastroenterology","Calcium Channel","Transmembrane Transporters","Pinaverium bromide (Icosapentaenoic acid) acts as a calcium channel blocker and is useful for functional gastrointestinal disorders.",591.42,"53251-94-8",100,169.08,16,27.05,"http://www.selleck.cn/products/pinaverium-bromide.html","C26H41Br2NO4","bromide","Icosapentaenoic acid","[Br-].COC1=C(OC)C=C(C[N+]2(CCOCCC3CCC4CC3C4(C)C)CCOCC2)C(=C1)Br",1.114,4,0,10]
["S6476","Eicosapentaenoic Acid","a3","L1300-28","in 10mM DMSO","DMF","Martindale the Extra Pharmacopoei",null,"Others","Immunology & Inflammation related","Immunology & Inflammation","Eicosapentaenoic acid (EPA) is an omega-3 polyunsaturated fatty acid with antiinflammatory properties, and is present in fish and fish oils, including salmon, cod, and krill oils.",302.45,"10417-94-4",60,198.38,"<1",0,"http://www.selleck.cn/products/eicosapentaenoic-acid.html","C20H30O2","Free Base",0,"CC/C=C\\C\\C=C/C/C=C\\C\\C=C/C/C=C\\CCCC(O)=O",5.994,1,0,13]
["S6478","Fipexide hydrochloride","b3","L1300-28","in 10mM DMSO","marketed in France and Italy",null,null,"Neurological Disease","cAMP","GPCR & G Protein","Fipexide (hydrochloride) is a psychoactive drug of the piperazine class.",425.31,"34161-23-4",85,199.85,"<1",0,"http://www.selleck.cn/products/fipexide-hydrochloride.html","C20H22Cl2N2O4","hydrochloride","N/A","Cl.ClC1=CC=C(OCC(=O)N2CCN(CC2)CC3=CC=C4OCOC4=C3)C=C1",3.434,4,0,5]
["S6484","uridine triacetate","c3","L1300-28","in 10mM DMSO","FDA,NDC",null,"208169,208159","Metabolic Disease","Others","Others","Uridine triacetate (Vistonuridine, PN401) is an orally active prodrug of the naturally occurring nucleoside uridine. It is used for the treatment of hereditary orotic aciduria (Xuriden), or for the emergency treatment of fluorouracil or capecitabine overdose or toxicity.",370.31,"4105-38-8",74,199.83,7,18.9,"http://www.selleck.cn/products/uridine-triacetate.html","C15H18N2O9","triacetate","Vistonuridine, PN401","CC(=O)OCC1OC(C(OC(C)=O)C1OC(C)=O)N2C=CC(=O)NC2=O",-1.314,9,1,8]
["S6487","fluticasone furoate","d3","L1300-28","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale the Extra Pharmacopoei","205625,022051","Immunology/Inflammation","Adrenergic Receptor","Neuronal Signaling","Fluticasone furoate (GW685698) is an inhaled corticosteroid/long-acting beta-agonist combination with a prolonged bronchodilator duration of action. It is used for the treatment of non-allergic and allergic rhinitis administered by a nasal spray.",538.58,"397864-44-7",100,185.67,"<1",0,"http://www.selleck.cn/products/fluticasone-furoate.html","C27H29F3O6S","free base","GW685698","CC1CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(OC(=O)C5=CC=CO5)C(=O)SCF",4.479,5,1,6]
["S6492","Doravirine (MK-1439)","e3","L1300-28","in 10mM DMSO","FDA,EMA,NDC",null,210806,"Infection","Reverse Transcriptase","Microbiology","Doravirine (MK-1439) is a novel HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50 values of 12, 9.7, and 9.7 nM against the wild type (WT) and K103N and Y181C reverse transcriptase (RT) mutants, respectively, in a biochemical assay. It is highly specific with minimum off-target activities.",425.75,"1338225-97-0",85,199.65,"<1",0,"http://www.selleck.cn/products/doravirine-mk-1439.html","C17H11C1F3N5O3","free base","N/A","CN1C(=O)NN=C1CN2C=CC(=C(OC3=CC(=CC(=C3)C#N)Cl)C2=O)C(F)(F)F",1.694,4,1,5]
["S6508","Mitapivat","f3","L1300-28","in 10mM DMSO","EMA; NDC ;",null,null,"Metabolic Disease","PKM","Metabolism","Mitapivat (AG-348) is an activator of a pyruvate kinase PKM2, an enzyme involved in glycolysis.",450.55,"1260075-17-9",90,199.76,"<1",0,"http://www.selleck.cn/products/mitapivat.html","C24H26N4O3S","free base","AG-348","O=C(N1CCN(CC1)CC2CC2)C3=CC=C(N[S](=O)(=O)C4=C5N=CC=CC5=CC=C4)C=C3",2.695,4,1,6]
["S6585","Triethylenetetramine Dihydrochloride","g3","L1300-28","in 10mM DMSO","DMF, EMA, NDC",null,null,"Others","Others","Others","Triethylenetetramine Dihydrochloride (TETA 2HCl, Trientine Dihydrochloride), a Cu(II)-selective chelator, is commonly used for the treatment of Wilson's disease.",219.16,"38260-01-4",15,68.44,44,200.77,"http://www.selleck.cn/products/triethylenetetramine-dihydrochloride.html","C6H20Cl2N4","Dihydrochloride","TETA 2HCl, Trientine Dihydrochloride","Cl.Cl.NCCNCCNCCN",-1.508,0,4,7]
["S6587","Clobetasone butyrate","h3","L1300-28","in 10mM DMSO","CFDA,PMDA,HMA","Martindale the Extra Pharmacopoei,EP8.8,BP2017",null,"Inflammation","Others","Others","Clobetasone butyrate is a new corticosteroid that is often employed topically as a treatment for a variety of conditions such as eczema, psoriasis, various forms of dermatitis, and also for certain ophthalmologic conditions.",478.98,"25122-57-0",96,200.43,"<1",0,"http://www.selleck.cn/products/clobetasone-butyrate.html","C26H32ClFO5","free base","N/A","CCCC(=O)OC1(C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(=O)CC12C)C(=O)CCl",4.515,5,0,6]
["S6588","Methylprednisolone hemisuccinate","a4","L1300-28","in 10mM DMSO","FDA,CFDA,DMF,NDC,PMDA,HMA","Martindale the Extra Pharmacopoei,KP Ⅹ,USP39-NF34","040583,040612,040641,040662,040709,040888,081266,081267,081268,086906,086953,087030,087812,087813,087851,087852,088523,088524,088676,088677,088678,088679,089143,089144,089186,089187,089188,089189,089264,089265,089266,089267,202691,207549,207667","Inflammation","Others","Others","Methylprednisolone sodium succinate is a glucocorticoid used to treat a variety health issues including severe allergic reactions, asthma, autoimmune diseases, blood disorders, gastrointestinal diseases and endocrine disorders.",474.54,"2921-57-5",95,200.19,"<1",0,"https://www.selleckchem.com/products/methylprednisolone-hemisuccinate-s6588.html","C26H34O8","free base","N/A","CC1CC2C3CCC(O)(C(=O)COC(=O)CCC(O)=O)C3(C)CC(O)C2C4(C)C=CC(=O)C=C14",1.736,5,1,7]
["S6590","Hydrocortisone butyrate","b4","L1300-28","in 10mM DMSO","FDA,CFDA,DMF,NDC,PMDA","Martindale the Extra Pharmacopoei,USP42-NF37,KP Ⅹ,JP17","076364,076654,076842,202145,205134,209556,210209","Immunology/Inflammation","Others","Others","Hydrocortisone butyrate is a potent topical corticosteroid that can be used to treat a range of inflammatory skin conditions.",432.55,"13609-67-1",87,201.13,"<1",0,"http://www.selleck.cn/products/hydrocortisone-butyrate.html","C25H36O6","free base","N/A","CCCC(=O)OC1(CCC2C3CCC4=CC(=O)CCC4(C)C3C(O)CC12C)C(=O)CO",2.785,4,2,6]
["S6601","(±)-Equol","c4","L1300-28","in 10mM DMSO","NDC",null,null,"Others","Estrogen/progestogen Receptor","Endocrinology & Hormones","(±)-Equol, an isoflavandiol estrogen, is a metabolite of the soy isoflavones, daidzin and daidzein.",242.27,"94105-90-5",48,198.13,"<1",0,"https://www.selleckchem.com/products/equol-1.html","C15H14O3","free base","N/A","OC1=CC=C(C=C1)C2COC3=C(C2)C=CC(=C3)O",3.211,1,2,1]
["S6611","Cyclothiazide","d4","L1300-28","in 10mM DMSO","FDA","Martindale the Extra Pharmacopoei","013157,018173","Cardiovascular Disease","GABA Receptor","Neuronal Signaling","Cyclothiazide is a positive allosteric modulator of ionotropic α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-type glutamate receptors with critical roles in neurological development and function.",389.88,"2259-96-3",78,200.06,"<1",0,"http://www.selleck.cn/products/cyclothiazide.html","C14H16ClN3O4S2","free base","N/A","N[S](=O)(=O)C1=CC2=C(NC(N[S]2(=O)=O)C3CC4CC3C=C4)C=C1Cl",1.228,4,3,2]
["S6614","Fursultiamine","e4","L1300-28","in 10mM DMSO","CFDA,NDC,PMDA","Martindale the Extra Pharmacopoei,KP Ⅹ,JP17",null,"Others","Vitamin","Metabolism","Fursultiamine (Thiamine tetrahydrofurfuryl disulfide) is a nutritional supplement and vitamin B1 derivative, with potential antineoplastic activity.",398.54,"804-30-8",80,200.73,3,7.53,"http://www.selleck.cn/products/fursultiamine.html","C17H26N4O3S2","free base","Thiamine tetrahydrofurfuryl disulfide","CC1=NC=C(CN(C=O)/C(C)=C(CCO)/SSCC2CCCO2)C(=N1)N",0.221,4,2,9]
["S7000","AP26113-analog (ALK-IN-1)","f4","L1300-28","in 10mM DMSO","EMA，FDA，NDC,PMDA,",null,"004248,208772","Cancer","ALK,EGFR","Protein Tyrosine Kinase","AP26113-analog (ALK-IN-1) is an analog of AP26113 which is a potent and selective ALK inhibitor. It is also an inhibitor of EGFR.",529.01,"1197958-12-5",45,85.06,"<1",0,"http://selleckchem.com/products/ap26113.html","C26H34ClN6O2P","free base","N/A","COC1=CC(=CC=C1NC2=NC=C(Cl)C(=N2)NC3=CC=CC=C3[P](C)(C)=O)N4CCC(CC4)N(C)C",5.126,6,2,8]
["S7007","Binimetinib (MEK162)","g4","L1300-28","in 10mM DMSO","FDA,EMA,NDC,PMDA",null,"210498","Cancer","Apoptosis related,Autophagy,MEK","MAPK","Binimetinib (MEK162, ARRY-162, ARRY-438162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM in a cell-free assay. Binimetinib induces G1 cell cycle arrest and apoptosis in human NSCLC cell lines and induces autophagy. Phase 3.",441.23,"606143-89-9",88,199.44,"<1",0,"http://selleckchem.com/products/mek162.html","C17H15BrF2N4O3","free base","ARRY-162,ARRY-438162","C[N]1C=NC2=C1C=C(C(=O)NOCCO)C(=C2F)NC3=C(F)C=C(Br)C=C3",2.775,3,3,6]
["S7025","Embelin","h4","L1300-28","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Cancer","Antineoplastic and Immunosuppressive Antibiotics,IAP","Apoptosis","Embelin (Embelic Acid, NSC 91874), a quinone isolated from the Japanese Ardisia herb, is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 μM in a cell-free assay.",294.39,"550-24-3",59,200.41,"<1",0,"http://selleckchem.com/products/embelin.html","C17H26O4","free base","Embelic Acid, NSC 91874","CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O",4.62,2,2,10]
["S7028","Duvelisib (IPI-145)","a5","L1300-28","in 10mM DMSO","FDA,NDC",null,"211155","Cancer","PI3K","Angiogenesis","Duvelisib (IPI-145, INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM in cell-free assays, highly selective for PI3K δ/γ than other protein kinases. Phase 3.",416.86,"1201438-56-3",83,199.11,"<1",0,"http://selleckchem.com/products/ipi-145-ink1197.html","C22H17ClN6O","free base","INK1197","CC(NC1=NC=NC2=C1N=C[NH]2)C3=CC4=CC=CC(=C4C(=O)N3C5=CC=CC=C5)Cl",3.648,4,2,4]
["S7059","Tezacaftor (VX-661)","b5","L1300-28","in 10mM DMSO","FDA,EMA,NDC",null,"210491","Endocrinology","CFTR","Transmembrane Transporters","Tezacaftor (VX-661) is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. Phase 2.",520.5,"1152311-62-0",100,192.12,"<1",0,"http://selleckchem.com/products/vx-661.html","C26H27F3N2O6","free base","N/A","CC(C)(CO)C1=CC2=CC(=C(F)C=C2[N]1CC(O)CO)NC(=O)C3(CC3)C4=CC=C5OC(F)(F)OC5=C4",5.215,3,4,8]
["S7067","Tepotinib (EMD 1214063)","c5","L1300-28","in 10mM DMSO","FDA，NDC,EMA,PMDA,",null,"005524,214096","Cancer","Autophagy,c-Met","Protein Tyrosine Kinase","Tepotinib (EMD 1214063, MSC2156119) is a potent and selective c-Met inhibitor with IC50 of 4 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib (EMD 1214063) induces autophagy. Phase 1.",492.57,"1100598-32-0",5,10.15,"<1",0,"http://selleckchem.com/products/emd-1214063.html","C29H28N6O2","free base","MSC2156119","CN1CCC(CC1)COC2=CN=C(N=C2)C3=CC=CC(=C3)CN4N=C(C=CC4=O)C5=CC(=CC=C5)C#N",3.629,5,0,7]
["S7077","Cilengitide trifluoroacetate","d5","L1300-28","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cancer/Hematology/Respiratory Disease","Integrin","Cytoskeletal Signaling","Cilengitide (EMD 121974, NSC 707544) is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.",702.68,"199807-35-7",100,142.31,8,11.38,"http://selleckchem.com/products/cilengitide-emd-121974-nsc-707544.html","C29H41F3N8O9","Trifluoroacetat","EMD 121974, NSC 707544","CC(C)C1N(C)C(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CCCNC(N)=N)NC1=O.OC(=O)C(F)(F)F",-0.565,7,6,11]
["S7083","Ceritinib (LDK378)","e5","L1300-28","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"205755,211225","Cancer/Respiratory Disease","ALK,FLT3,IGF-1R,Serine/threonin kinase","Protein Tyrosine Kinase","Ceritinib (LDK378) is a potent inhibitor against ALK with IC50 of 0.2 nM in cell-free assays. Ceritinib (LDK378) also inhibits IGF-1R, InsR, STK22D and FLT3 with IC50 of 8 nM, 7 nM, 23 nM and 60 nM, respectively. Phase 3.",558.14,"1032900-25-6",20,35.83,"<1",0,"http://selleckchem.com/products/ldk378.html","C28H36ClN5O3S","free base","N/A","CC(C)OC1=C(NC2=NC(=C(Cl)C=N2)NC3=C(C=CC=C3)[S](=O)(=O)C(C)C)C=C(C)C(=C1)C4CCNCC4",6.479,5,3,9]
["S7091","Zotarolimus (ABT-578)","f5","L1300-28","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Others","FKBP,mTOR","PI3K/Akt/mTOR","Zotarolimus (ABT-578,A 179578) is an analogue of rapamycin, and inhibits FKBP-12 binding with IC50 of 2.8 nM.",966.21,"221877-54-9",100,103.5,"<1",0,"http://selleckchem.com/products/zotarolimus-abt-578.html","C52H79N5O12","free base","A 179578","COC1CC(CCC1[N]2C=NN=N2)CC(C)C3CC(=O)C(C)/C=C(C)/C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC4CCC(C)C(O)(O4)C(=O)C(=O)N5CCCCC5C(=O)O3)OC",5.793,13,1,7]
["S7121","Tovorafenib (MLN2480)","g5","L1300-28","in 10mM DMSO","FDA,NDC",null,"217700,218033","Cancer","Raf","MAPK","Tovorafenib (MLN2480, BIIB-024, TAK580, AMG-2112819, BSK1369, DAY-101) is an oral, selective pan-Raf kinase inhibitor in chinical trials.",506.29,"1096708-71-2",100,197.52,"<1",0,"http://selleckchem.com/products/mln2480.html","C17H12Cl2F3N7O2S","free base","BIIB-024, TAK580, AMG-2112819, BSK1369, DAY-101","CC(NC(=O)C1=C(Cl)C(=NC=N1)N)C2=NC=C(S2)C(=O)NC3=NC=C(Cl)C(=C3)C(F)(F)F",2.932,6,3,6]
["S7156","Marimastat (BB-2516)","h5","L1300-28","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cancer","MMP","Proteases","Marimastat (BB-2516, TA2516) is a broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 with IC50 of 3 nM, 5 nM, 6 nM, 9 nM and 13 nM, respectively. Phase 3.",331.41,"154039-60-8",54,162.94,"<1",0,"http://selleckchem.com/products/marimastat.html","C15H29N3O5","free base","TA2516","CNC(=O)C(NC(=O)C(CC(C)C)C(O)C(=O)NO)C(C)(C)C",0.239,3,4,8]
["S7158","Abemaciclib mesylate (LY2835219)","a6","L1300-28","in 10mM DMSO","FDA,EMA,NDC,PMDA",null,"208716,208855","Cancer","CDK","Cell Cycle","Abemaciclib (LY2835219) is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively. Phase 3.",602.7,"1231930-82-7",83,137.71,100,165.92,"http://selleckchem.com/products/ly2835219.html","C27H32F2N8.CH4O3S","mesylate","N/A","CCN1CCN(CC1)CC2=CC=C(NC3=NC(=C(F)C=N3)C4=CC(=C5N=C(C)[N](C(C)C)C5=C4)F)N=C2.C[S](O)(=O)=O",4.543,4,1,7]
["S7160","Glasdegib (PF-04449913)","b6","L1300-28","in 10mM DMSO","FDA,NDC",null,"210656","Cancer","Hedgehog/Smoothened","Stem Cells & Wnt","Glasdegib (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2.",374.44,"1095173-27-5",47,125.52,"<1",0,"http://selleckchem.com/products/glasdegib-pf-04449913.html","C21H22N6O","Free Base","N/A","CN1CCC(CC1C2=NC3=CC=CC=C3[NH]2)NC(=O)NC4=CC=C(C=C4)C#N",2.363,2,3,3]
["S7179","Siponimod (BAF312)","c6","L1300-28","in 10mM DMSO","FDA",null,"209884","Neurological Disease","S1P Receptor","GPCR & G Protein","BAF312 (Siponimod) is a next-generation S1P receptor agonist, selective for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, exhibits >1000-fold selectivity over S1P2, S1P3 and S1P4 receptors. Phase 3.",516.6,"1230487-00-9",100,193.57,"<1",0,"http://selleckchem.com/products/baf312-siponimod.html","C29H35F3N2O3","free base","N/A","CCC1=CC(=CC=C1CN2CC(C2)C(O)=O)\\C(C)=N\\OCC3=CC=C(C4CCCCC4)C(=C3)C(F)(F)F",3.834,3,0,10]
["S7194","Olverembatinib dimesylate (HQP1351)","d6","L1300-28","in 10mM DMSO","CFDA",null,null,"Cancer","Bcr-Abl","Angiogenesis","Olverembatinib dimesylate (HQP1351, GZD824) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC50 of 0.34 nM and 0.68 nM, respectively.",724.77,"1421783-64-3",100,137.97,100,137.97,"http://selleckchem.com/products/gzd824.html","C29H27F3N6O.2CH4O3S","Mesylate","GZD824 Dimesylate","CN1CCN(CC1)CC2=C(C=C(NC(=O)C3=CC(=C(C)C=C3)C#CC4=CC5=C([NH]N=C5)N=C4)C=C2)C(F)(F)F.C[S](O)(=O)=O.C[S](O)(=O)=O",4.047,3,2,7]
["S7252","Selinexor (KPT-330)","e6","L1300-28","in 10mM DMSO","FDA, NDC",null,212306,"Cancer","CRM1","Transmembrane Transporters","Selinexor (KPT-330, ATG-010) is an orally bioavailable selective CRM1 inhibitor. Phase 2.",443.31,"1393477-72-9",88,198.51,"<1",0,"http://selleckchem.com/products/kpt-330.html","C17H11F6N7O","free base","ATG-010","FC(F)(F)C1=CC(=CC(=C1)C2=N[N](\\C=C/C(=O)NNC3=CN=CC=N3)C=N2)C(F)(F)F",2.345,5,2,7]
["S7280","Edoxaban tosylate Monohydrate","f6","L1300-28","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"206316","Angiology/Cardiovascular Disease","Factor Xa","Metabolism","Edoxaban (DU-176b) is a selective factor Xa inhibitor with Ki of 0.561 nM, >10 000-fold selectivity over thrombin and FIXa, and is also an orally bioavailable anticoagulant drug.",738.27,"1229194-11-9",100,135.45,"<1",0,"http://selleckchem.com/products/edoxaban.html","C24H30ClN7O4S.C7H8O3S.H2O","Tosylate hydrate","DU-176b","O.CN(C)C(=O)C1CCC(NC(=O)C(=O)NC2=CC=C(Cl)C=N2)C(C1)NC(=O)C3=NC4=C(CN(C)CC4)S3.CC5=CC=C(C=C5)[S](O)(=O)=O",2.286,6,3,7]
["S7297","Osimertinib (AZD9291)","h6","L1300-28","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"208065","Cancer/Respiratory Disease","EGFR","Protein Tyrosine Kinase","Osimertinib (AZD9291) is an oral, irreversible, and mutant-selective EGFR inhibitor with IC50 of 12.92, 11.44 and 493.8 nM for Exon 19 deletion EGFR, L858R/T790M EGFR, and WT EGFR in LoVo cells, respectively. Phase 3.",499.61,"1421373-65-0",99,198.15,"<1",0,"http://selleckchem.com/products/azd9291.html","C28H33N7O2","free base","Mereletinib","COC1=C(NC2=NC=CC(=N2)C3=C[N](C)C4=C3C=CC=C4)C=C(NC(=O)C=C)C(=C1)N(C)CCN(C)C",4.671,4,2,10]
["S7303","Rilpivirine","a7","L1300-28","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"205302","Infection","Reverse Transcriptase","Microbiology","Rilpivirine (R278474, TMC27, DB08864) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), and used to treat HIV-1 infection.",366.42,"500287-72-9",73,199.22,"<1",0,"http://selleckchem.com/products/rilpivirine.html","C22H18N6","free base","R278474, TMC278, DB08864","CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N",5.409,2,2,5]
["S7397","Sorafenib (BAY 43-9006)","b7","L1300-28","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","207012","Cancer","Apoptosis related,Autophagy,Ferroptosis,FLT3,PDGFR,Raf,VEGFR","MAPK","Sorafenib (BAY 43-9006, NSC-724772) is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.",464.82,"284461-73-0",63,135.54,"<1",0,"http://selleckchem.com/products/sorafenib.html","C21H16ClF3N4O3","Free Base","NSC-724772,BAY 43-9006","CNC(=O)C1=CC(=CC=N1)OC2=CC=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2",4.175,4,3,6]
["S7411","Ascomycin (FK520)","c7","L1300-28","in 10mM DMSO","DMF",null,null,"Infection","Anti-infection","Microbiology","Ascomycin (FK520, FR 900520, Immunomycin), an FK-506 analog, is a neutral macrolide immunosuppressant, which prevents rejection after an organ transplant. Phase 3.",792.01,"104987-12-4",100,126.26,"<1",0,"http://selleckchem.com/products/ascomycin-fk520.html","C43H69NO12","free base","FR 900520, Immunomycin","CCC1/C=C(C)/CC(C)CC(OC)C2OC(O)(C(C)CC2OC)C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)C(O)CC1=O)\\C(C)=C\\C4CCC(O)C(C4)OC",4.766,9,2,6]
["S7417","Puromycin (CL13900) 2HCl","d7","L1300-28","in 10mM DMSO","DMF",null,null,"Infection","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Selection Antibiotics for Transfected Cell","Microbiology","Puromycin 2HCl (CL13900) is an aminonucleoside antibiotic, which acts as a protein synthesis inhibitor.",544.43,"58-58-2",100,183.68,100,183.68,"http://selleckchem.com/products/Puromycin-2HCl.html","C22H29N7O5.2HCl","Dihydrochloride","N/A","Cl.Cl.COC1=CC=C(CC(N)C(=O)NC2C(O)C(OC2CO)[N]3C=NC4=C3N=CN=C4N(C)C)C=C1",0.586,6,4,8]
["S7440","Ribociclib (LEE011)","e7","L1300-28","in 10mM DMSO","FDA,EMA,NDC",null,"209092","Cancer","CDK","Cell Cycle","Ribociclib (LEE011) is an orally available, and highly specific inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM. Phase 3.",434.54,"1211441-98-3",7,16.11,"<1",0,"http://selleckchem.com/products/lee011.html","C23H30N8O","free base","N/A","CN(C)C(=O)C1=CC2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2[N]1C5CCCC5",2.9,4,2,5]
["S7470","Triapine","g7","L1300-28","in 10mM DMSO","DMF",null,null,"Cancer","DNA/RNA Synthesis,RNR","DNA Damage/DNA Repair","Triapine (3-AP) is a potent ribonucleotide reductase (RNR) inhibitor with broad spectrum antitumor activity by inhibiting DNA synthesis. Phase 2.",195.24,"200933-27-3",20,102.44,"<1",0,"http://selleckchem.com/products/triapine.html","C7H9N5S","free base","3-AP","NC(=S)N/N=C/C1=NC=CC=C1N",0.331,2,3,3]
["S7505","(S)-crizotinib","h7","L1300-28","in 10mM DMSO","FDA,EMA,NDC,PMDA",null,"202570","Cancer/Respiratory Disease","MTH1,NUDIX","DNA Damage/DNA Repair","(S)-crizotinib, the (S)-enantiomer of crizotinib, is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM in a cell-free assay.",450.34,"1374356-45-2",42,93.26,"<1",0,"http://selleckchem.com/products/s-crizotinib.html","C21H22Cl2FN5O","free base","N/A","CC(OC1=C(N)N=CC(=C1)C2=C[N](N=C2)C3CCNCC3)C4=C(Cl)C=CC(=C4Cl)F",3.693,3,2,5]
["S7513","Trelagliptin","a8","L1300-28","in 10mM DMSO","PMDA",null,null,"Endocrinology/Metabolic Disease","DPP","Proteases","Trelagliptin (SYR-472), a potent, orally active and highly selective DPP-4 inhibitor with an IC50 of 4 nM, improves glycemic control in vivo and can be used for the study of type 2 diabetes mellitus (T2DM).",357.38,"865759-25-7",71,198.67,"<1",0,"http://selleckchem.com/products/trelagliptin.html","C18H20FN5O2","free base","SYR-472","CN1C(=O)C=C(N2CCCC(N)C2)N(CC3=CC(=CC=C3C#N)F)C1=O",1.476,2,1,3]
["S7536","Lorlatinib (PF-6463922)","b8","L1300-28","in 10mM DMSO","FDA,NDC,PMDA",null,"210868","Cancer","ALK,Apoptosis related,ROS1","Protein Tyrosine Kinase","Lorlatinib (PF-6463922) is a potent, dual ALK/ROS1 inhibitor with Ki of <0.02 nM, <0.07 nM, and 0.7 nM for ROS1, ALK (WT), and ALK (L1196M), respectively. PF-06463922 induces apoptosis. Phase 1.",406.41,"1454846-35-5",81,199.31,"<1",0,"http://selleckchem.com/products/pf-06463922.html","C21H19FN6O2","free base","N/A","CC1OC2=C(N)N=CC(=C2)C3=C(C#N)[N](C)N=C3CN(C)C(=O)C4=C1C=C(F)C=C4",2.343,4,1,0]
["S7550","Erythromycin Cyclocarbonate","c8","L1300-28","in 10mM DMSO","CFDA",null,null,"Infection","Bacterial","Microbiology","Erythromycin Cyclocarbonate(Davercin), derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome.",759.92,"55224-05-0",100,131.59,"<1",0,"http://selleckchem.com/products/erythromycin-cyclocarbonate.html","C38H65NO14","free base","Davercin","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)C(=O)C(C)C4OC(=O)OC14C",3.172,11,2,7]
["S7559","Darolutamide (ODM-201)","d8","L1300-28","in 10mM DMSO","DMF",null,null,"Cancer","Androgen Receptor","Endocrinology & Hormones","Darolutamide (ODM-201, BAY-1841788) is a novel androgen receptor (AR) antagonist that blocks AR nuclear translocation with Ki of 11 nM. Phase 3.",398.85,"1297538-32-9",80,200.58,"<1",0,"http://selleckchem.com/products/odm-201.html","C19H19ClN6O2","free base","BAY-1841788","CC(O)C1=CC(=N[NH]1)C(=O)NC(C)C[N]2C=CC(=N2)C3=CC(=C(C=C3)C#N)Cl",3.034,3,3,6]
["S7579","Ledipasvir (GS5885)","e8","L1300-28","in 10mM DMSO","FDA,DMF,NDC",null,"205834","Infection","COVID-19,HCV Protease","Microbiology","Ledipasvir (GS5885) is a HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection.",889,"1256388-51-8",100,112.49,"<1",0,"http://selleckchem.com/products/ledipasvir-gs5885.html","C49H54F2N8O6","free base","N/A","COC(=O)NC(C(C)C)C(=O)N1C2CCC(C2)C1C3=NC4=CC=C(C=C4[NH]3)C5=CC=C6C7=CC=C(C=C7C(F)(F)C6=C5)C8=CN=C([NH]8)C9CCC%10(CC%10)N9C(=O)C(NC(=O)OC)C(C)C",7.304,8,4,12]
["S7594","Abscisic Acid (Dormin)","f8","L1300-28","in 10mM DMSO","NDC",null,null,"Others","Others","Endocrinology & Hormones","Abscisic Acid (Dormin, Abscisin II) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth.",264.32,"21293-29-8",52,196.73,"<1",0,"http://selleckchem.com/products/abscisic-acid-dormin.html","C15H20O4","free base","Abscisin II","CC(/C=C/C1(O)C(=CC(=O)CC1(C)C)C)=C/C(O)=O",2.161,2,0,3]
["S7605","Filgotinib (GLPG0634)","g8","L1300-28","in 10mM DMSO","EMA,PMDA",null,"005113","Cancer","JAK","JAK/STAT","Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Phase 2.",425.5,"1206161-97-8",85,199.76,"<1",0,"http://selleckchem.com/products/filgotinib.html","C21H23N5O3S","free base","N/A","O=C(NC1=N[N]2C(=N1)C=CC=C2C3=CC=C(CN4CC[S](=O)(=O)CC4)C=C3)C5CC5",2.461,5,1,5]
["S7625","Niraparib (MK-4827) tosylate","h8","L1300-28","in 10mM DMSO","FDA,EMA,NDC",null,"208447","Cancer","Apoptosis related,PARP","DNA Damage/DNA Repair","Niraparib tosylate (MK-4827, ZEJULA) is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. Niraparib increases formation of PARP-DNA complexes resulting in DNA damage, apoptosis, and cell death.",492.59,"1038915-73-9",98,198.95,"<1",0,"http://selleckchem.com/products/mk-4827-niraparib-tosylate.html","C19H20N4O.C7H8O3S","4-?methylbenzen","Niraparib tosylate, MK 4827 tosylate, ZEJULA","CC1=CC=C(C=C1)[S](O)(=O)=O.NC(=O)C2=CC=CC3=C[N](N=C23)C4=CC=C(C=C4)C5CCCNC5",4.267,2,2,4]
["S7633","Lomitapide Mesylate","a9","L1300-28","in 10mM DMSO","FDA,DMF,NDC",null,"203858","Cardiovascular Disease","MTP","Transmembrane Transporters","Lomitapide Mesylate(AEGR-733 Mesylate,BMS-2138 Mesylate) is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia.",789.83,"202914-84-9",100,126.61,"<1",0,"http://selleckchem.com/products/lomitapide-mesylate.html","C40H41F6N3O5S","Mesylate","AEGR-733 Mesylate,BMS-2138 Mesylate","C[S](O)(=O)=O.FC(F)(F)CNC(=O)C1(CCCCN2CCC(CC2)NC(=O)C3=C(C=CC=C3)C4=CC=C(C=C4)C(F)(F)F)C5=C(C=CC=C5)C6=C1C=CC=C6",7.377,2,2,12]
["S7635","Lomitapide","b9","L1300-28","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"203858","Cardiovascular Disease","MTP","Transmembrane Transporters","Lomitapide (AEGR-733, BMS-201038) is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia.",692.71,"182431-12-5",100,144.36,"<1",0,"http://selleckchem.com/products/lomitapide.html","C39H37F6N3O2","free base","AEGR-733, BMS-201038","FC(F)(F)CNC(=O)C1(CCCCN2CCC(CC2)NC(=O)C3=C(C=CC=C3)C4=CC=C(C=C4)C(F)(F)F)C5=C(C=CC=C5)C6=C1C=CC=C6",7.79,2,2,12]
["S7650","Peficitinib (ASP015K)","c9","L1300-28","in 10mM DMSO","PMDA",null,null,"Immunology/Inflammation","JAK","JAK/STAT","Peficitinib (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.",326.39,"944118-01-8",65,199.15,"<1",0,"http://selleckchem.com/products/peficitinb-asp015k-jnj-54781532.html","C18H22N4O2","free base","JNJ-54781532","NC(=O)C1=C(N[CH]2C3C[CH]4CC2C[C](O)(C4)C3)C5=C([NH]C=C5)N=C1",1.023,2,3,3]
["S7660","Obeticholic Acid","d9","L1300-28","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"207999","Gastroenterology","Autophagy,FXR","Metabolism","Obeticholic Acid (INT-747, 6-ECDCA, 6-Ethylchenodeoxycholic acid) is a potent and selective farnesoid X receptor (FXR) agonist with EC50 of 99 nM. Obeticholic Acid inhibits autophagy. Phase 3.",420.63,"459789-99-2",84,199.7,"<1",0,"http://selleckchem.com/products/obeticholic-acid.html","C26H44O4","free base","INT-747, 6-ECDCA, 6-Ethylchenodeoxycholic acid","CCC1C(O)C2C3CCC(C(C)CCC(O)=O)C3(C)CCC2C4(C)CCC(O)CC14",4.79,1,2,5]
["S7663","Ruboxistaurin (LY333531) HCl","e9","L1300-28","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Endocrinology/Metabolic Disease","PKC","TGF-beta/Smad","Ruboxistaurin (LY333531) HCl is a β-specific protein kinase C inhibitor. It competitively and reversibly inhibits PKCβ1 and PKCβ2 with IC50 values of 4.7 and 5.9 nM respectively.",505.01,"169939-93-9",50,99.01,"<1",0,"http://selleckchem.com/products/ly333531.html","C28H28N4O3.HCl","hydrochloride","Ruboxistaurin hydrochloride,  LY333531 hydrochloride","Cl.CN(C)CC1CC[N]2C=C(C3=C2C=CC=C3)C4=C(C(=O)NC4=O)C5=C[N](CCO1)C6=C5C=CC=C6",3.861,3,1,2]
["S7668","Picropodophyllin (PPP)","f9","L1300-28","in 10mM DMSO","DMF",null,null,"Cancer","Apoptosis related,IGF-1R","Protein Tyrosine Kinase","Picropodophyllin (PPP, AXL1717) is a IGF-1R inhibitor with IC50 of 1 nM. It displays selectivity for IGF-1R and does not coinhibit tyrosine phosphorylation the IR, or of a selected panel of receptors less related to IGF-IR(FGF-R, PDGF-R, OR EGF-R). Picropodophyllin (PPP) induces apoptosis with antineoplastic activity.",414.41,"477-47-4",82,197.87,"<1",0,"http://selleckchem.com/products/picropodophyllin-ppp.html","C22H22O8","free base","AXL1717","COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(O)C4=CC5=C(OCO5)C=C24",2.111,7,1,4]
["S7672","Omaveloxolone (RTA-408)","g9","L1300-28","in 10mM DMSO","EMA,FDA,NDC",null,"006084,216718 ","Cancer/Inflammation/Immunology","NF-κB,Nrf2","NF-κB","Omaveloxolone (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.",554.71,"1474034-05-3",100,180.27,"<1",0,"http://selleckchem.com/products/omaveloxolone-rta-408.html","C33H44F2N2O3","free base","N/A","CC1(C)CCC2(CCC3(C)C(C2C1)C(=O)C=C4C3(C)CCC5C(C)(C)C(=O)C(=CC45C)C#N)NC(=O)C(C)(F)F",5.339,3,1,2]
["S7674","Savolitinib (AZD6094)","h9","L1300-28","in 10mM DMSO","CFDA",null,null,"Cancer","c-Met","Protein Tyrosine Kinase","Savolitinib (Volitinib, AZD6094, HMPL-504) is a novel, potent, and selective MET inhibitor currently in clinical development in various indications, including PRCC. The IC50 values of this compound for c-Met and p-Met are 5 nM and 3 nM, respectively. It shows exquisite selectivity for c-Met over 274 kinase.",345.36,"1313725-88-0",16,46.33,"<1",0,"http://selleckchem.com/products/hmpl-504-azd6094-volitinib.html","C17H15N9","free base","HMPL-504, Volitinib","CC([N]1N=NC2=NC=C(N=C12)C3=C[N](C)N=C3)C4=C[N]5C=CN=C5C=C4",1.032,6,0,3]
["S7678","Sacubitril/valsartan (LCZ696)","a10","L1300-28","in 10mM DMSO","DMF,EMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017,IP2010",null,"Cardiovascular Disease","Angiotensin Receptor,Apoptosis related,Neprilysin","Proteases","Sacubitril/valsartan (LCZ696, Sacubitril, Valsartan), consisting of valsartan and sacubitril in 1:1 molar ratio, is an orally bioavailable, dual-acting angiotensin receptor-neprilysin inhibitor (ARNi) for hypertension and heart failure. Phase 3.",915.98,"936623-90-4",30,32.75,100,109.17,"http://selleckchem.com/products/lcz696.html","C24H29N5O3.C24H29NO5.5/2H2O.3Na","Sodium salt hydrate","Sacubitril, Valsartan","[Na+].[Na+].[Na+].CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NN=N[NH]3)C(C(C)C)C(O)=O.CCOC(=O)C(C)CC(CC4=CC=C(C=C4)C5=CC=CC=C5)NC(=O)CCC(O)=O",8.591,9,2,22]
["S7721","Monomethyl auristatin E (MMAE)","b10","L1300-28","in 10mM DMSO","DMF",null,null,"Cancer","ADC Cytotoxin,Microtubule Associated","Cytoskeletal Signaling","Monomethyl auristatin E (MMAE, SGD-1010) is a synthetic antineoplastic agent, which is linked to a monoclonal antibody (MAB). It is also a microtubule-disrupting agent .",717.98,"474645-27-7",100,139.28,"<1",0,"http://selleckchem.com/products/monomethyl-auristatin-e-mmae.html","C39H67N5O7","free base","SGD-1010","CCC(C)C(C(CC(=O)N1CCCC1C(OC)C(C)C(=O)NC(C)C(O)C2=CC=CC=C2)OC)N(C)C(=O)C(NC(=O)C(NC)C(C)C)C(C)C",3.46,6,4,20]
["S7754","Gilteritinib (ASP2215)","c10","L1300-28","in 10mM DMSO","FDA,NDC,PMDA",null,"211349","Cancer","Axl,FLT3","Protein Tyrosine Kinase","Gilteritinib (ASP2215) is a small-molecule FLT3/AXL inhibitor with IC50 values of 0.29 nM and 0.73 nM for FLT3 and AXL, respectively. It inhibits FLT3 at an IC50 value that was approximately 800-fold more potent than the concentration required to inhibit c-KIT (230 nM).",552.71,"1254053-43-4",100,180.93,"<1",0,"http://selleckchem.com/products/gilteritinib-asp2215.html","C29H44N8O3","free base","N/A","CCC1=NC(=C(NC2=CC=C(N3CCC(CC3)N4CCN(C)CC4)C(=C2)OC)N=C1NC5CCOCC5)C(N)=O",2.401,5,3,9]
["S7766","Cabotegravir (GSK1265744)","d10","L1300-28","in 10mM DMSO","FDA,EMA,NDC,DMF,PMDA,CFDA",null,"005756,004976,212888,215499,212887","Infection","Integrase","Microbiology","Cabotegravir (GSK744, GSK1265744, S/GSK1265744) is a long-acting HIV integrase inhibitor against a broad range of HIV subtypes, and inhibits the HIV-1 integrase catalyzed strand transfer reaction with IC50 of 3.0 nM. Phase 2.",405.35,"1051375-10-0",38,93.75,"<1",0,"http://selleckchem.com/products/cabotegravir-gsk744-gsk1265744.html","C19H17F2N3O5","free base","GSK744, S/GSK1265744","CC1COC2CN3C=C(C(=O)NCC4=C(F)C=C(F)C=C4)C(=O)C(=C3C(=O)N12)O",0.237,4,2,3]
["S7781","Sunitinib (SU11248)","e10","L1300-28","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","201275,021938,021968","Cancer","Apoptosis related,Autophagy,c-Kit,IRE1,PDGFR,VEGFR","Protein Tyrosine Kinase","Sunitinib (SU11248) is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit. Sunitinib is also a dose-dependent inhibitor of the autophosphorylation activity of IRE1α. Sunitinib induces autophagy and apoptosis.",398.47,"557795-19-4",25,62.74,"<1",0,"http://selleckchem.com/products/sunitinib.html","C22H27FN4O2","free base","SU11248","CCN(CC)CCNC(=O)C1=C(C)[NH]C(=C1C)/C=C/2C(=O)NC3=C2C=C(F)C=C3",2.997,2,3,7]
["S7782","Dasatinib Monohydrate","f10","L1300-28","in 10mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia",null,"Cancer/Hematology","Bcr-Abl,c-Kit,Src","Angiogenesis","Dasatinib Monohydrate (BMS-354825) is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.",506.02,"863127-77-9",21,41.5,"<1",0,"http://selleckchem.com/products/dasatinib-monohydrate.html","C22H28ClN7O3S","Monohydrate","BMS-354825 Monohydrate","O.CC1=NC(=CC(=N1)NC2=NC=C(S2)C(=O)NC3=C(C)C=CC=C3Cl)N4CCN(CCO)CC4",3.232,4,3,7]
["S7783","Combretastatin A4","g10","L1300-28","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cancer","Microtubule Associated","Cytoskeletal Signaling","Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.Phase 3.",316.35,"117048-59-6",63,199.15,"<1",0,"http://selleckchem.com/products/combretastatin-a4.html","C18H20O5","free base","N/A","COC1=C(O)C=C(\\C=C/C2=CC(=C(OC)C(=C2)OC)OC)C=C1",3.508,4,1,6]
["S7784","Fumagillin","h10","L1300-28","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Angiology/Cancer","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics","Microbiology","Fumagillin(Amebacilin,NSC9168) is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.",458.54,"23110-15-8",92,200.64,"<1",0,"http://selleckchem.com/products/fumagillin.html","C26H34O7","free base","Amebacilin,NSC9168","COC1C(CCC2(CO2)C1C3(C)OC3CC=C(C)C)OC(=O)\\C=C\\C=C\\C=C\\C=C\\C(O)=O",3.421,6,0,11]
["S7786","Erlotinib (OSI-774)","a11","L1300-28","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","091002,091059,208488","Cancer/Respiratory Disease","Autophagy,EGFR","Protein Tyrosine Kinase","Erlotinib (OSI-774, CP358774, NSC 718781, Tarceva) is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Erlotinib induces autophagy.",393.44,"183321-74-6",78,198.25,"<1",0,"http://selleckchem.com/products/erlotinib.html","C22H23N3O4","free base","CP358774, NSC 718781, Tarceva","COCCOC1=C(OCCOC)C=C2C(=NC=NC2=C1)NC3=CC=CC(=C3)C#C",4.309,6,1,10]
["S7787","Docetaxel Trihydrate","b11","L1300-28","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017,IP2010",null,"Cancer/Respiratory Disease","Microtubule Associated","Cytoskeletal Signaling","Docetaxel (RP56976, NSC 628503), an analog of paclitaxel, is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules.",861.93,"148408-66-6",100,116.02,"<1",0,"http://selleckchem.com/products/docetaxel-trihydrate.html","C43H53NO14.3H2O","Trihydrate","RP56976 (NSC 628503) Trihydrate","O.O.O.CC(=O)OC12COC1CC(O)C3(C)C2C(OC(=O)C4=CC=CC=C4)C5(O)CC(OC(=O)C(O)C(NC(=O)OC(C)(C)C)C6=CC=CC=C6)C(=C(C(O)C3=O)C5(C)C)C",1.964,10,4,13]
["S7810","Afatinib (BIBW2992) Dimaleate","c11","L1300-28","in 10mM DMSO","FDA,DMF",null,"201292","Cancer","Autophagy,EGFR,HER2","Protein Tyrosine Kinase","Afatinib (BIBW2992) Dimaleate irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant. Afatinib (BIBW2992) Dimaleate induces autophagy.",717.18,"850140-73-7",100,139.44,"<1",0,"http://selleckchem.com/products/afatinib-bibw2992-dimaleate.html","C24H25ClFN5O3.2C4H4O4","Dimaleate","N/A","CN(C)C/C=C/C(=O)NC1=C(OC2CCOC2)C=C3N=CN=C(NC4=CC=C(F)C(=C4)Cl)C3=C1.OC(=O)\\C=C/C(O)=O.OC(=O)\\C=C/C(O)=O",0.96,9,2,12]
["S7818","Pexidartinib (PLX3397)","d11","L1300-28","in 10mM DMSO","FDA,NDC",null,211810,"Cancer","Apoptosis related,c-Kit,CSF-1R,FLT3","Protein Tyrosine Kinase","Pexidartinib (PLX3397) is an oral, potent multi-targeted receptor tyrosine kinase inhibitor of CSF-1R, Kit (c-Kit), and FLT3 with IC50 of 20 nM, 10 nM and 160 nM, respectively. Pexidartinib (PLX3397) induces apoptosis and necrosis with antitumor activity. Phase 3.",417.81,"1029044-16-3",83,198.65,"<1",0,"http://selleckchem.com/products/pexidartinib-plx3397.html","C20H15ClF3N5","free base","N/A","FC(F)(F)C1=NC=C(CNC2=NC=C(CC3=C[NH]C4=NC=C(Cl)C=C34)C=C2)C=C1",4.811,3,2,6]
["S7834","Cyclo (-RGDfK)","e11","L1300-28","in 10mM DMSO","DMF,NDC",null,null,"Others","Integrin","Cytoskeletal Signaling","Cyclo (-RGDfK) is a potent and selective αvβ3 integrin inhibitor.",717.69,"500577-51-5",100,139.34,84,117.04,"http://selleckchem.com/products/cyclo-rgdfk.html","C29H42F3N9O9","free base","N/A","NCCCCC1NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CCCNC(N)=N)NC1=O.OC(=O)C(F)(F)F",-4.172,7,8,14]
["S7844","Cyclo(RGDyK)","f11","L1300-28","in 10mM DMSO","DMF,NDC",null,null,"Others","Integrin","Cytoskeletal Signaling","Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.",847.72,"250612-42-1",100,117.96,100,117.96,"http://selleckchem.com/products/cyclo-rgdyk.html","C31H43F6N9O12","ditrifluoroacetic acid","N/A","NCCCCC1NC(=O)C(CC2=CC=C(O)C=C2)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CCCNC(N)=N)NC1=O.OC=O.OC(=O)C(F)(F)F.FC(F)F",-3.67,8,10,14]
["S7852","Eliglustat","g11","L1300-28","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"205494","Metabolic Disease","Glucosylceramide Synthase","Metabolism","Eliglustat (GENZ-112638) inhibits glucosylceramide synthase(GCS) (IC50=20 nM in intact MDCK cells), thus reducing the load of glucosylceramide influx into the lysosome.",404.54,"491833-29-5",80,197.76,"<1",0,"http://selleckchem.com/products/eliglustat.html","C23H36N2O4","Tartrate","GENZ-112638","CCCCCCCC(=O)NC(CN1CCCC1)C(O)C2=CC=C3OCCOC3=C2",3.808,3,2,11]
["S7856","Tenofovir Alafenamide (GS-7340)","h11","L1300-28","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"208464","Infection","Reverse Transcriptase","Microbiology","Tenofovir Alafenamide (GS-7340) is a prodrug of tenofovir, which is a reverse transcriptase inhibitor, used to treat HIV and Hepatitis B.",476.47,"379270-37-8",95,199.38,"<1",0,"http://selleckchem.com/products/tenofovir-alafenamide-gs-7340.html","C21H29N6O5P","free base","N/A","CC(C)OC(=O)C(C)N[P](=O)(COC(C)C[N]1C=NC2=C1N=CN=C2N)OC3=CC=CC=C3",1.526,8,2,12]
["S7858","Dibutyryl-cAMP (Bucladesine)","a2","L1300-29","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","PDE,PKA","GPCR & G Protein","Dibutyryl-cAMP (Bucladesine, dbcAMP) is a cell-permeable PKA activator by mimicing the action of endogenous cAMP. Dibutyryl-cAMP (Bucladesine) is also a phosphodiesterase (PDE) inhibitor.",491.37,"16980-89-5",98,199.44,98,199.44,"http://selleckchem.com/products/dibutyryl-camp-bucladesine.html","C18H23N5NaO8P","sodium salt","dbcAMP","CCCC(=O)NC1=NC=NC2=C1N=C[N]2C3OC4CO[P](=O)(O[Na])OC4C3OC(=O)CCC",1.028,10,1,9]
["S7867","Oleuropein","b2","L1300-29","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cardiovascular Disease/Inflammation","Anti-infection,Apoptosis related,Aromatase,PPAR","Immunology & Inflammation","Oleuropein is an antioxidant polyphenol isolated from olive leaf. Oleuropein exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Oleuropein inhibits PPARγ activity. Oleuropein exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity. Oleuropein also inhibits aromatase. Oleuropein induces apoptosis. Phase 2.",540.51,"32619-42-4",100,185.01,100,185.01,"http://selleckchem.com/products/oleuropein.html","C25H32O13","free base","N/A","COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)\\C(=C\\C)C1CC(=O)OCCC3=CC(=C(O)C=C3)O",0.166,7,6,11]
["S7935","Y-39983 HCl","c2","L1300-29","in 10mM DMSO","DMF",null,null,"Others","ROCK","Cell Cycle","Y-39983 HCl (Y-33075) is a selective rho-associated protein kinase(ROCK) inhibitor with an IC50 of 3.6 nM.",353.25,"173897-44-4",63,178.34,63,178.34,"http://selleckchem.com/products/y-39983-hcl.html","C16H16N4O.2HCl","dihydrochloride","Y-33075 HCl","Cl.Cl.CC(N)C1=CC=C(C=C1)C(=O)NC2=C3C=C[NH]C3=NC=C2",2.204,2,3,3]
["S7936","Belumosudil (KD025)","d2","L1300-29","in 10mM DMSO","NDC;FDA",null,null,"Inflammation/Immunology; Cancer","ROCK","Cell Cycle","Belumosudil (KD025, SLx-2119) is an orally available, and selective ROCK2 inhibitor with IC50 and Ki of 60 nM and 41 nM, respectively. Phase 2.",452.51,"911417-87-3",90,198.89,"<1",0,"http://selleckchem.com/products/kd025-(slx-2119).html","C26H24N6O2","free base","SLx-2119","CC(C)NC(=O)COC1=CC(=CC=C1)C2=NC3=CC=CC=C3C(=N2)NC4=CC5=C([NH]N=C5)C=C4",4.51,5,3,7]
["S7952","Ozanimod (RPC1063)","e2","L1300-29","in 10mM DMSO","FDA, EMA, NDC",null,209899,"Neurological Disease","S1P Receptor","GPCR & G Protein","Ozanimod (RPC1063) is a selective oral S1P Receptor 1 modulator. Phase 3.",404.46,"1306760-87-1",81,200.27,"<1",0,"http://selleckchem.com/products/ozanimod-rpc1063.html","C23H24N4O3","free base","N/A","CC(C)OC1=CC=C(C=C1C#N)C2=NC(=NO2)C3=CC=CC4=C3CCC4NCCO",3.291,4,2,7]
["S7953","ETC-1002","f2","L1300-29","in 10mM DMSO","FDA, EMA, NDC",null,211616,"Cardiovascular Disease","AMPK,ATP-citrate lyase,LDL","PI3K/Akt/mTOR","ETC-1002 (Bempedoic acid, ESP-55016),also known as Bempedoic acid, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies.ETC-1002 is an activator of hepatic AMP-activated protein kinase (AMPK). It has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM).",344.49,"738606-46-7",68,197.39,"<1",0,"http://selleckchem.com/products/etc-1002.html","C19H36O5","free base","Bempedoic acid, ESP-55016","CC(C)(CCCCCC(O)CCCCCC(C)(C)C(O)=O)C(O)=O",5.18,2,1,14]
["S7960","Larotrectinib (LOXO-101) sulfate","h2","L1300-29","in 10mM DMSO","FDA,NDC",null,"210861;211710","Cancer","Apoptosis related,Trk receptor","Protein Tyrosine Kinase","Larotrectinib sulfate (LOXO-101, ARRY-470) is an oral potent and selective ATP-competitive inhibitor of tropomyosin receptor kinases (TRK). Larotrectinib inhibition of TRKs induces cellular apoptosis and G1 cell-cycle arrest.",526.51,"1223405-08-0",100,189.93,"<1",0,"http://selleckchem.com/products/loxo-101.html","C21H22F2N6O2.H2SO4","sulfate","ARRY-470, Larotrectinib","OC1CCN(C1)C(=O)NC2=C3N=C(C=C[N]3N=C2)N4CCCC4C5=CC(=CC=C5F)F.O[S](O)(=O)=O",1.374,3,2,3]
["S7975","Favipiravir (T-705)","a3","L1300-29","in 10mM DMSO","PMDA",null,null,"Infection","COVID-19,DNA/RNA Synthesis,Influenza Virus","DNA Damage/DNA Repair","Favipiravir (T-705) is a potent and selective RNA-dependent RNA polymerase inhibitor, used to treat influenza virus infections.",157.1,"259793-96-9",31,197.33,5,31.83,"http://selleckchem.com/products/favipiravir-t-705.html","C5H4FN3O2","free base","N/A","NC(=O)C1=NC(=CN=C1O)F",-0.157,3,2,1]
["S7995","Ripasudil (K-115) hydrochloride dihydrate","b3","L1300-29","in 10mM DMSO","PMDA",null,null,"Ophthalmology","ROCK","Cell Cycle","Ripasudil (K-115) hydrochloride dihydrate is a potent ROCK inhibitor with IC50 of 51 nM and 19 nM for ROCK1 and ROCK2, respectively, used for the treatment of glaucoma and ocular hypertension.",395.88,"887375-67-9",26,65.68,79,199.56,"http://selleckchem.com/products/ripasudil-k-115.html","C15H18FN3O2S.ClH.2H2O","Hydrochloride dihydrate","N/A","O.O.Cl.CC1CNCCCN1[S](=O)(=O)C2=CC=CC3=CN=CC(=C23)F",0.739,3,1,2]
["S7998","Entrectinib (RXDX-101)","c3","L1300-29","in 10mM DMSO","FDA,NDC,PMDA",null,"212725 ,212726","Cancer","ALK,Autophagy,ROS1,Trk receptor","Protein Tyrosine Kinase","Entrectinib (RXDX-101, NMS-E628) is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. Entrectinib (RXDX-101) induces autophagy. Phase 2.",560.64,"1108743-60-7",100,178.37,"<1",0,"http://selleckchem.com/products/entrectinib-rxdx-101.html","C31H34F2N6O2","free base","NMS-E628","CN1CCN(CC1)C2=CC=C(C(=O)NC3=N[NH]C4=C3C=C(CC5=CC(=CC(=C5)F)F)C=C4)C(=C2)NC6CCOCC6",4.952,3,3,7]
["S8016","Vonoprazan Fumarate (TAK-438)","d3","L1300-29","in 10mM DMSO","DMF,PMDA",null,null,"Infection/Inflammation","Potassium Channel","Transmembrane Transporters","Vonoprazan Fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. Phase 3.",461.46,"1260141-27-2",62,134.36,"<1",0,"http://selleckchem.com/products/tak-438.html","C17H16FN3O2S.C4H4O4","Fumarate","N/A","CNCC1=C[N](C(=C1)C2=CC=CC=C2F)[S](=O)(=O)C3=CC=CN=C3.OC(=O)\\C=C\\C(O)=O",0.017,5,1,7]
["S8018","Nirogacestat (PF-03084014)","e3","L1300-29","in 10mM DMSO","NDC;FDA",null,null,"Cancer","Apoptosis related,Secretase","Proteases","Nirogacestat (PF-03084014, PF-3084014) is a selective gamma-secretase inhibitor with IC50 of 6.2 nM in a cell-free assay. Nirogacestat (PF-03084014, PF-3084014) induces apoptosis. Phase 2.",489.64,"1290543-63-3",97,198.1,"<1",0,"http://selleckchem.com/products/pf-03084014-pf-3084014.html","C27H41F2N5O","free base","PF-3084014","CCCC(NC1CCC2=CC(=CC(=C2C1)F)F)C(=O)NC3=C[N](C=N3)C(C)(C)CNCC(C)(C)C",5.042,2,3,11]
["S8019","Capivasertib (AZD5363)","f3","L1300-29","in 10mM DMSO","FDA; NDC; PMDA",null,218197,"Cancer","Akt","PI3K/Akt/mTOR","Capivasertib (AZD5363) potently inhibits all isoforms of Akt(Akt1/Akt2/Akt3) with IC50 of 3 nM/8 nM/8 nM in cell-free assays, similar to P70S6K/PKA and lower activity towards ROCK1/2. Phase 2.",428.92,"1143532-39-1",86,200.5,"<1",0,"http://selleckchem.com/products/azd5363.html","C21H25ClN6O2","free base","N/A","NC1(CCN(CC1)C2=NC=NC3=C2C=C[NH]3)C(=O)NC(CCO)C4=CC=C(Cl)C=C4",1.317,3,4,6]
["S8022","Empagliflozin (BI 10773)","g3","L1300-29","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"204629","Endocrinology/Metabolic Disease","SGLT","GPCR & G Protein","Empagliflozin (BI-10773) is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. Phase 3.",450.91,"864070-44-0",90,199.6,"<1",0,"http://selleckchem.com/products/empagliflozin-bi10773.html","C23H27ClO7","free base","N/A","OCC1OC(C(O)C(O)C1O)C2=CC(=C(Cl)C=C2)CC3=CC=C(OC4CCOC4)C=C3",1.839,3,4,6]
["S8034","Apremilast (CC-10004)","h3","L1300-29","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"205437,206088","Immunology","PDE,TNF-alpha","Metabolism","Apremilast (CC-10004) is a potent and orally active PDE4 and TNF-α inhibitor with IC50 of 74 nM and 77 nM, respectively.",460.5,"608141-41-9",92,199.78,"<1",0,"http://selleckchem.com/products/apremilast-cc-10004.html","C22H24N2O7S","free base","CC-10004","CCOC1=C(OC)C=CC(=C1)C(C[S](C)(=O)=O)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(C)=O",1.509,7,1,8]
["S8041","Cobimetinib (GDC-0973)","a4","L1300-29","in 10mM DMSO","FDA,NDC,EMA",null,"206192","Cancer","Apoptosis related,MEK","MAPK","Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, showing more than 100-fold selectively for MEK1 over MEK2 and showed no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Cobimetinib induces apoptosis. Phase 3.",531.31,"934660-93-2",100,188.21,"<1",0,"http://selleckchem.com/products/cobimetinib-gdc-0973-rg7420.html","C21H21F3IN3O2","free base","RG7420,XL518","OC1(CN(C1)C(=O)C2=C(NC3=CC=C(I)C=C3F)C(=C(F)C=C2)F)C4CCCCN4",3.701,1,2,4]
["S8048","Venetoclax (ABT-199)","b4","L1300-29","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"208573","Cancer","Autophagy,Bcl-2","Apoptosis","Venetoclax (ABT-199, GDC-0199) is a Bcl-2-selective inhibitor with Ki of <0.01 nM in cell-free assays, >4800-fold more selective versus Bcl-xL and Bcl-w, and no activity to Mcl-1. Venetoclax is reported to induce cell growth suppression, apoptosis, cell cycle arrest, and autophagy in triple negative breast cancer MDA-MB-231 cells. Phase 3.",868.44,"1257044-40-8",100,115.15,"<1",0,"http://selleckchem.com/products/abt-199.html","C45H50ClN7O7S","free base","GDC-0199","CC1(C)CCC(=C(C1)C2=CC=C(Cl)C=C2)CN3CCN(CC3)C4=CC(=C(C=C4)C(=O)N[S](=O)(=O)C5=CC=C(NCC6CCOCC6)C(=C5)[N+]([O-])=O)OC7=CN=C8[NH]C=CC8=C7",7.94,6,3,13]
["S8051","Macitentan (ACT 064992)","c4","L1300-29","in 10mM DMSO","FDA,DMF,EMA,NDC",null,"204410","Cardiovascular Disease","Endothelin Receptor","GPCR & G Protein","Macitentan (ACT 064992) is an orally active, non-peptide, dual ETA/ETB (endothelin) receptor antagonist with IC50 of 0.5 nM/391 nM.",588.27,"441798-33-0",100,169.99,"<1",0,"http://selleckchem.com/products/macitentan.html","C19H20Br2N6O4S","free base","ACT 064992","CCCN[S](=O)(=O)NC1=NC=NC(=C1C2=CC=C(Br)C=C2)OCCOC3=NC=C(Br)C=N3",3.671,8,2,11]
["S8057","Pacritinib (SB1518)","d4","L1300-29","in 10mM DMSO","FDA,NDC",null,"208712 ","Cancer","FLT3,JAK","JAK/STAT","Pacritinib (SB1518) is a potent and selective inhibitor of Janus Kinase 2 (JAK2) and Fms-Like Tyrosine Kinase-3 (FLT3) with IC50s of 23 and 22 nM in cell-free assays, respectively. Phase 3.",472.58,"937272-79-2",11,23.28,"<1",0,"http://selleckchem.com/products/pacritinib-sb1518.html","C28H32N4O3","free base","N/A","C1CCN(C1)CCOC2=CC=C3NC4=NC=CC(=N4)C5=CC(=CC=C5)COC\\C=C\\COCC2=C3",4.547,5,1,4]
["S8067","Vorapaxar (MK-5348)","e4","L1300-29","in 10mM DMSO","FDA,NDC,EMA",null,"204886","Cardiovascular Disease","PAR","GPCR & G Protein","Vorapaxar (SCH 530348, MK-5348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM.",492.58,"618385-01-6",99,200.98,"<1",0,"http://selleckchem.com/products/vorapaxar.html","C29H33FN2O4","free base","SCH 530348","CCOC(=O)NC1CCC2C(C1)CC3C(C(C)OC3=O)C2\\C=C\\C4=CC=C(C=N4)C5=CC=CC(=C5)F",5.261,5,1,6]
["S8078","Bardoxolone Methyl","f4","L1300-29","in 10mM DMSO","EMA",null,"005869","Cancer","Apoptosis related,Autophagy,Ferroptosis,IκB/IKK,NF-κB,Nrf2","NF-κB","Bardoxolone Methyl (RTA 402, TP-155, NSC 713200, CDDO Methyl Ester, CDDO-Me) is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities; Also a potent Nrf2 activator and nuclear factor-κB (NF-κB) inhibitor. Bardoxolone Methyl abrogates ferroptosis. Bardoxolone methyl induces apoptosis and autophagy in cancer cells.",505.69,"218600-53-4",21,41.53,"<1",0,"http://selleckchem.com/products/bardoxolone-methyl.html","C32H43NO4","free base","RTA 402, TP-155, NSC 713200, CDDO Methyl Ester, CDDO-Me","COC(=O)C12CCC(C)(C)CC1C3C(=O)C=C4C(C)(CCC5C(C)(C)C(=O)C(=CC45C)C#N)C3(C)CC2",5.798,4,0,2]
["S8101","CB-5083","g4","L1300-29","in 10mM DMSO","DMF",null,null,"Others","ATPase,p97","Transmembrane Transporters","CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor with IC50 of 11 nM. Phase 1.",413.47,"1542705-92-9",82,198.32,"<1",0,"http://selleckchem.com/products/cb-5083.html","C24H23N5O2","free base","N/A","CC1=CC2=C(C=CC=C2C(N)=O)[N]1C3=NC4=C(COCC4)C(=N3)NCC5=CC=CC=C5",3.748,4,2,5]
["S8103","Sotagliflozin (LX4211)","h4","L1300-29","in 10mM DMSO","EMA",null,null,"Endocrinology/Metabolic Disease","SGLT","GPCR & G Protein","Sotagliflozin (LX4211, LP-802034) is an oral dual SGLT1/SGLT2 inhibitor with IC50 of 36 nM and 1.8 nM, respectively. Phase 3.",424.94,"1018899-04-1",84,197.67,"<1",0,"http://selleckchem.com/products/sotagliflozin-lx4211.html","C21H25ClO5S","free base","LP-802034","CCOC1=CC=C(CC2=C(Cl)C=CC(=C2)C3OC(SC)C(O)C(O)C3O)C=C1",3.734,2,3,6]
["S8116","Acalabrutinib (ACP-196)","a5","L1300-29","in 10mM DMSO","FDA,NDC",null,"210259","Cancer/Hematology","BTK","Angiogenesis","Acalabrutinib (ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor with an IC50 of 3 nM, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity over ibrutinib with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, respectively) and no activity against EGFR.",465.51,"1420477-60-6",93,199.78,"<1",0,"http://selleckchem.com/products/acalabrutinib.html","C26H23N7O2","free base","N/A","CC#CC(=O)N1CCCC1C2=NC(=C3[N]2C=CN=C3N)C4=CC=C(C=C4)C(=O)NC5=NC=CC=C5",2.699,5,2,5]
["S8133","Resiquimod (R-848)","b5","L1300-29","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Infection","HCV,IFN,Interleukins,TLR,TNF-alpha","Immunology & Inflammation","Resiquimod (R-848, S28463) is an immune response modifier that acts as a potent TLR 7/TLR 8 agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α. Resiquimod reduces hepatitis C virus (HCV) infection. Phase 2.",314.38,"144875-48-9",63,200.39,"<1",0,"http://selleckchem.com/products/resiquimod.html","C17H22N4O2","free base","S28463","CCOCC1=NC2=C([N]1CC(C)(C)O)C3=C(C=CC=C3)N=C2N",1.919,3,1,5]
["S8134","Radotinib","c5","L1300-29","in 10mM DMSO","marketed in South Korea",null,null,"Cancer","Bcr-Abl","Angiogenesis","Radotinib (IY-5511) is a selective BCR-ABL1 tyrosine kinase inhibitor with IC50 of 34 nM, used to treat Chronic Myeloid Leukemia.",530.5,"926037-48-1",100,188.5,"<1",0,"http://selleckchem.com/products/radotinib.html","C27H21F3N8O","free base","IY-5511","CC1=C[N](C=N1)C2=CC(=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C)C(=C3)NC4=NC=CC(=N4)C5=NC=CN=C5",4.362,6,2,7]
["S8135","Riociguat (BAY 63-2521)","d5","L1300-29","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,"204819","Cardiovascular Disease","Guanylate Cyclase","GPCR & G Protein","Riociguat (BAY 63-2521) is an oral soluble guanylate cyclase (GC) stimulator, used in the treatment of ipulmonary hypertension.",422.42,"625115-55-1",84,198.85,"<1",0,"http://selleckchem.com/products/riociguat-bay-63-2521.html","C20H19FN8O2","free base","N/A","COC(=O)N(C)C1=C(N)N=C(N=C1N)C2=N[N](CC3=CC=CC=C3F)C4=NC=CC=C24",2.341,6,2,5]
["S8136","Sivelestat (ONO-5046)","e5","L1300-29","in 10mM DMSO","DMF,PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Respiratory Disease","Serine Protease","Proteases","Sivelestat (ONO5046, LY544349, EI546) is a potent and selective inhibitor of neutrophil elastase with IC50 of 44nM. It almost shows no activity at a range of other proteases.",434.46,"127373-66-4",86,197.95,"<1",0,"http://selleckchem.com/products/sivelestat-ono-5046.html","C20H22N2O7S","Free Base","ONO5046, LY544349, EI546","CC(C)(C)C(=O)OC1=CC=C(C=C1)[S](=O)(=O)NC2=CC=CC=C2C(=O)NCC(O)=O",2.321,6,2,9]
["S8144","Halofuginone","f5","L1300-29","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Cancer","DNA/RNA Synthesis,TGF-beta/Smad","DNA Damage/DNA Repair","Halofuginone (RU-19110) is the competitively inhibitor of  prolyl-tRNA synthetase with Ki of 18.3 nM.It could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in mammal.",414.68,"55837-20-2",20,48.23,"<1",0,"http://selleckchem.com/products/halofuginone.html","C16H17BrClN3O3","free base","RU-19110","OC1CCCNC1CC(=O)CN2C=NC3=CC(=C(Cl)C=C3C2=O)Br",1.648,3,2,4]
["S8166","tirabrutinib(ONO-4059) hydrochloride","g5","L1300-29","in 10mM DMSO","PMDA",null,null,"Cancer/Inflammation/Immunology","BTK","Angiogenesis","Tirabrutinib Hydrochloride (ONO-4059, GS-4059) is a highly potent and selective BTK inhibitor with an IC50 of 2.2 nM.",490.94,"1439901-97-9",98,199.62,"<1",0,"http://selleckchem.com/products/ono-4059-gs-4059.html","C25H22N6O3.HCl","hydrochloride","GS-4059","Cl.CC#CC(=O)N1CCC(C1)N2C(=O)N(C3=CC=C(OC4=CC=CC=C4)C=C3)C5=C(N)N=CN=C25",3.706,5,1,5]
["S8171","Daprodustat (GSK1278863)","h5","L1300-29","in 10mM DMSO","EMA,FDA,NDC,DMF,PMDA",null,"005746,216951","Cardiovascular Disease","HIF","Angiogenesis","Daprodustat (GSK1278863) is an orally administered hypoxia-inducible factor-prolyl hydroxylase (HIF-PH) inhibitor. Phase 2.",393.43,"960539-70-2",10,25.42,"<1",0,"http://selleckchem.com/products/daprodustat.html","C19H27N3O6","free base","N/A","OC(=O)CNC(=O)C1C(=O)N(C2CCCCC2)C(=O)N(C3CCCCC3)C1=O",1.747,5,1,5]
["S8183","Pimavanserin tartrate","a6","L1300-29","in 10mM DMSO","FDA,NDC,DMF",null,"207318,210793","Neurological Disease","5-HT Receptor","GPCR & G Protein","Pimavanserin tartrate(ACP-103) is a potent and selective serotonin 5-HT2A inverse agonist with pIC50 of 8.73, used to treat psychosis associated with Parkinson’s disease.",1005.2,"706782-28-7",100,99.48,100,99.48,"http://selleckchem.com/products/pimavanserin.html","C50H68F2N6O4.C4H6O6","tartrate","ACP-103","CC(C)COC1=CC=C(CNC(=O)N(CC2=CC=C(F)C=C2)C3CCN(C)CC3)C=C1.CC(C)COC4=CC=C(CNC(=O)N(CC5=CC=C(F)C=C5)C6CCN(C)CC6)C=C4.OC(C(O)C(O)=O)C(O)=O",0.735,6,4,19]
["S8194","umbralisib (TGR-1202)","b6","L1300-29","in 10mM DMSO","FDA",null,"213176","Cancer","PI3K","PI3K/Akt/mTOR","Umbralisib (TGR-1202, Rp-5264), a novel, next generation PI3Kδ inhibitor, inhibits PI3Kδ activity in enzyme and cell based assays with IC50 and EC50 values of 22.2 & 24.3 nM, respectively.",571.55,"1532533-67-7",100,174.96,"<1",0,"http://selleckchem.com/products/tgr-1202.html","C31H24F3N5O3","free base","Rp-5264","CC(C)OC1=C(F)C=C(C=C1)C2=N[N](C(C)C3=C(C4=CC(=CC=C4)F)C(=O)C5=CC(=CC=C5O3)F)C6=C2C(=NC=N6)N",6.393,6,1,6]
["S8195","Oclacitinib maleate","c6","L1300-29","in 10mM DMSO","EMA",null,null,"Immunology/Inflammation","JAK","JAK/STAT","Oclacitinib maleate (PF-03394197) is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM. It does not inhibit a panel of 38 non-JAK kinases.",453.51,"1640292-55-2",90,198.45,18,39.69,"http://selleckchem.com/products/oclacitinib-maleate.html","C15H23N5O2S.C4H4O4","maleate","PF-03394197","CN[S](=O)(=O)CC1CCC(CC1)N(C)C2=C3C=C[NH]C3=NC=N2.OC(=O)\\C=C/C(O)=O",1.758,6,2,7]
["S8205","Enasidenib (AG-221)","d6","L1300-29","in 10mM DMSO","FDA,NDC",null,"209606","Cancer","Dehydrogenase","Metabolism","Enasidenib (AG-221) is a first-in-class, oral, potent, reversible, selective inhibitor of the IDH2 mutant enzyme.",473.38,"1446502-11-9",94,198.57,"<1",0,"http://selleckchem.com/products/ag-221-enasidenib.html","C19H17F6N7O","free base","N/A","CC(C)(O)CNC1=NC(=NC(=N1)NC2=CC=NC(=C2)C(F)(F)F)C3=NC(=CC=C3)C(F)(F)F",4.878,5,2,8]
["S8206","Ivosidenib (AG-120)","e6","L1300-29","in 10mM DMSO","FDA,NDC",null,"211192","Cancer","Dehydrogenase","Metabolism","Ivosidenib (AG-120) is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity.",582.96,"1448347-49-6",100,171.54,"<1",0,"http://selleckchem.com/products/ag-120-Ivosidenib.html","C28H22ClF3N6O3","free base",0,"FC1=CN=CC(=C1)N(C(C(=O)NC2CC(F)(F)C2)C3=C(Cl)C=CC=C3)C(=O)C4CCC(=O)N4C5=NC=CC(=C5)C#N",3.004,5,1,7]
["S8241","Ponesimod","f6","L1300-29","in 10mM DMSO","EMA; FDA; NDC",null,213498,"Inflammation/Immunology","S1P Receptor","GPCR & G Protein","Ponesimod (ACT-128800) is an orally active, selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator with EC50 of 5.7 nM.",460.97,"854107-55-4",92,199.58,"<1",0,"http://selleckchem.com/products/ponesimod-act-128800.html","C23H25ClN2O4S","free base","ACT-128800","CCCN=C1S\\C(=C/C2=CC=C(OCC(O)CO)C(=C2)Cl)C(=O)N1C3=CC=CC=C3C",4.941,3,2,8]
["S8294","Olmutinib (BI 1482694)","g6","L1300-29","in 10mM DMSO","marketed in South Korea",null,null,"Cancer","BTK,EGFR","Protein Tyrosine Kinase","Olmutinib (BI 1482694) is a novel third-generation epidermal growth factor receptor (EGFR) mutation-specific tyrosine kinase inhibitor (TKI). Also a potent inhibitor of Bruton's tyrosine kinase.",486.59,"1353550-13-6",97,199.35,"<1",0,"http://selleckchem.com/products/olmutinib-hm61713-bi-1482694.html","C26H26N6O2S","free base","HM61713","CN1CCN(CC1)C2=CC=C(NC3=NC(=C4SC=CC4=N3)OC5=CC=CC(=C5)NC(=O)C=C)C=C2",5.449,4,2,7]
["S8362","Tucatinib","h6","L1300-29","in 10mM DMSO","FDA, NDC",null,213411,"Cancer","EGFR,HER2","Protein Tyrosine Kinase","Tucatinib (Irbinitinib, ONT-380, ARRY-380) is an oral, potent, selective, reversible and ATP-competitive small-molecule inhibitor of ErbB-2 (also called HER2) with IC50s of 8 nM and 7 nM for ErbB-2 and p95 HER2, respectively in cell-based assays, showing ~500-fold selective for HER2 vs EGFR. It has potential antineoplastic activity.",480.52,"937263-43-9",96,199.78,"<1",0,"http://selleckchem.com/products/arry-380-ont-380.html","C26H24N8O2","free base","Irbinitinib, ONT-380, ARRY-380","CC1=CC(=CC=C1OC2=CC3=NC=N[N]3C=C2)NC4=NC=NC5=CC=C(NC6=NC(C)(C)CO6)C=C45",4.744,7,2,6]
["S8401","Erdafitinib (JNJ-42756493)","a7","L1300-29","in 10mM DMSO","FDA",null,212018,"Cancer","Apoptosis related,c-Kit,c-RET,CSF-1R,FGFR,PDGFR,VEGFR","Angiogenesis","Erdafitinib (JNJ-42756493) is a potent and selective orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. Erdafitinib also binds to RET (c-RET), CSF-1R, PDGFR-α/PDGFR-β, FLT4, Kit (c-Kit) and VEGFR-2 and induces cellular apoptosis.",446.54,"1346242-81-6",89,199.31,"<1",0,"http://selleckchem.com/products/jnj-42756493-erdafitinib.html","C25H30N6O2","free base","N/A","COC1=CC(=CC(=C1)N(CCNC(C)C)C2=CC3=NC(=CN=C3C=C2)C4=C[N](C)N=C4)OC",3.943,5,1,9]
["S8432","Troglitazone (CS-045)","b7","L1300-29","in 10mM DMSO","FDA,HMA","Martindale:The Extra Pharmacopoeia","020719 ,020720","Endocrinology/Metabolic Disease","Apoptosis related,Autophagy,Ferroptosis,PPAR","Metabolism","Troglitazone (Rezulin, Romglizone, Prelay, CS045, Romozin) is a potent agonist for the peroxisome proliferator-activated receptor-(PPAR) that is a ligand activated transcription factor regulating cell differentiation and growth. Troglitazone induces autophagy, apoptosis and necroptosis in bladder cancer cells. Troglitazone prevents RSL3-induced ferroptosis and lipid peroxidation in Pfa1 cells.",441.54,"97322-87-7",88,199.3,"<1",0,"http://selleckchem.com/products/troglitazone-cs-045.html","C24H27NO5S","free base","Rezulin, Romglizone, Prelay, Romozin","CC1=C(O)C(=C2CCC(C)(COC3=CC=C(CC4SC(=O)NC4=O)C=C3)OC2=C1C)C",5.682,4,2,5]
["S8538","Ritlecitinib (PF-06651600)","c7","L1300-29","in 10mM DMSO","EMA,FDA,NDC,PMDA",null,"006025,215830,","Inflammation/Immunology","JAK","JAK/STAT","Ritlecitinib (PF-06651600) is a potent and irreversible JAK3-selective inhibitor with an IC50 of 33.1 nM but without activity (IC50 > 10 000 nM) against JAK1, JAK2, and TYK2.",285.34,"1792180-81-4",57,199.76,0,0,"http://selleckchem.com/products/pf-06651600.html","C15H19N5O","free base","N/A","CC1CCC(CN1C(=O)C=C)NC2=C3C=C[NH]C3=NC=N2",1.854,3,2,3]
["S8539","TAS-102","d7","L1300-29","in 10mM DMSO","FDA",null,"207981","Cancer","DNA/RNA Synthesis,Thymidylate Synthase","DNA Damage/DNA Repair","TAS-102 (Trifluridine-Tipiracil Hydrochloride Mixture) is an orally administered combination of a thymidine-based nucleic acid analogue, trifluridine, and a thymidine phosphorylase inhibitor, tipiracil hydrochloride.",435.76,"733030-01-8",100,114.74,15,17.21,"http://selleckchem.com/products/tas-102.html","C10H11F3N2O5.0.5C9H11ClN4O2.0.5HCl","hydrochloride","Trifluridine-Tipiracil Hydrochloride Mixture","Cl.OCC1OC(CC1O)N2C=C(C(=O)NC2=O)C(F)(F)F.OCC3OC(CC3O)N4C=C(C(=O)NC4=O)C(F)(F)F.ClC5=C(CN6CCCC6=N)NC(=O)NC5=O",-1.951,8,8,8]
["S8540","Voxelotor (GBT440)","e7","L1300-29","in 10mM DMSO","FDA,NDC",null,213137,"Hematology","Others","Others","Voxelotor (GBT440, GTx011) is a novel small molecule hemoglobin modifier which increases hemoglobin oxygen affinity.",337.37,"1446321-46-5",67,198.6,"<1",0,"http://selleckchem.com/products/gbt440.html","C19H19N3O3","free base","GTx011","CC(C)[N]1N=CC=C1C2=NC=CC=C2COC3=CC=CC(=C3C=O)O",3.378,4,1,6]
["S8555","Asciminib (ABL001)","f7","L1300-29","in 10mM DMSO","EMA; NDC;FDA",null,null,"Cancer","Bcr-Abl","Angiogenesis","Asciminib (ABL001) is a potent and selective allosteric ABL1 inhibitor with dissociation constant (Kd) of 0.5-0.8 nM and selectivity to the myristoyl pocket of ABL1.",449.84,"1492952-76-7",89,197.85,0,0,"http://selleckchem.com/products/asciminib-abl001.html","C20H18ClF2N5O3","free base","N/A","OC1CCN(C1)C2=C(C=C(C=N2)C(=O)NC3=CC=C(OC(F)(F)Cl)C=C3)C4=CC=N[NH]4",4.196,4,3,6]
["S8558","Tofogliflozin(CSG 452)","g7","L1300-29","in 10mM DMSO","PMDA",null,null,"Endocrinology/Metabolic Disease","SGLT","GPCR & G Protein","Tofogliflozin (CSG 452) is a novel sodium-glucose co-transporter 2(SGLT2) inhibitor with IC50 values of 2.9 nM and 8444 nM for hSGLT2 and hSGLT1, respectively.",404.45,"1201913-82-7",84,207.69,4,9.89,"http://selleckchem.com/products/tofogliflozin-csg-452.html","C22H26O6.H2O","hydrate","N/A","O.CCC1=CC=C(CC2=CC3=C(COC34OC(CO)C(O)C(O)C4O)C=C2)C=C1",1.92,2,4,4]
["S8565","Omarigliptin (MK-3102)","h7","L1300-29","in 10mM DMSO","PMDA",null,null,"Endocrinology/Metabolic Disease","DPP","Proteases","Omarigliptin (MK-3102) is a competitive, reversible inhibitor of DPP-4 (IC50 = 1.6 nM, Ki = 0.8 nM). It is highly selective over all proteases tested (IC50 > 67 μM), including QPP, FAP, PEP, DPP8, and DPP9 and has weak ion channel activity (IC50 > 30 μM at IKr, Caγ1.2, and Naγ1.5).",398.43,"1226781-44-7",79,198.28,"<1",0,"http://selleckchem.com/products/omarigliptin-mk-3102.html","C17H20F2N4O3S","free base","N/A","C[S](=O)(=O)[N]1C=C2CN(CC2=N1)C3COC(C(N)C3)C4=C(F)C=CC(=C4)F",1.098,4,1,3]
["S8567","Tucidinostat (Chidamide)","a8","L1300-29","in 10mM DMSO","CFDA",null,null,"Cancer","HDAC","Epigenetics","Tucidinostat (Chidamide, HBI-8000, CS-055) is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.",390.41,"1616493-44-7",78,199.79,"<1",0,"http://selleckchem.com/products/tucidinostat-chidamide.html","C22H19FN4O2","free base","HBI-8000, CS-055","NC1=C(NC(=O)C2=CC=C(CNC(=O)\\C=C\\C3=CC=CN=C3)C=C2)C=C(F)C=C1",2.182,3,3,6]
["S8583","Repotrectinib (TPX-0005)","b8","L1300-29","in 10mM DMSO","FDA ; NDC",null,"218213","Cancer","ALK,ROS1,Src,Trk receptor","Protein Tyrosine Kinase","Repotrectinib (TPX-0005) is a novel ALK/ROS1/TRK inhibitor with the IC50 values of 1.01 nM for WT ALK, 1.26 nM for ALK(G1202R), and 1.08 nM for ALK(L1196M); also a potent SRC inhibitor (IC50 5.3 nM).",355.37,"1802220-02-5",70,196.98,"<1",0,"http://selleckchem.com/products/tpx-0005.html","C18H18FN5O2","free base","N/A","CC1CNC(=O)C2=C3N=C(NC(C)C4=C(O1)C=CC(=C4)F)C=C[N]3N=C2",2.005,4,2,0]
["S8592","Pamiparib (BGB-290)","c8","L1300-29","in 10mM DMSO","CFDA",null,null,"Cancer","PARP","DNA Damage/DNA Repair","Pamiparib (BGB-290) is a potent and selective inhibitor of PARP1 and PARP2 with IC50 values of 0.83 and 0.11 nM, respectively in biochemical assays. It shows high selectivity over other PARP enzymes.",298.31,"1446261-44-4",59,197.78,"<1",0,"http://www.selleckchem.com/products/bgb-290.html","C16H15FN4O","Free Base","N/A","CC12CCCN1CC3=NNC(=O)C4=CC(=CC5=C4C3=C2[NH]5)F",2.078,2,2,0]
["S8594","Tirofiban Hydrochloride","d8","L1300-29","in 10mM DMSO","FDA,DMF,HMA","Martindale:The Extra Pharmacopoeia","206888","Cardiovascular Disease","Integrin","Cytoskeletal Signaling","Tirofiban Hydrochloride (MK-383) is the hydrochloride salt form of tirofiban, a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation. It is more soluable than Tirofiban.",495.07,"150915-40-5",95,191.89,95,191.89,"http://selleckchem.com/products/tirofiban-hydrochlorid.html","C22H36N2O5S.HCl.H2O","hydrochloride hydrate","MK-383 Hydrochloride","O.Cl.CCCC[S](=O)(=O)NC(CC1=CC=C(OCCCCC2CCNCC2)C=C1)C(O)=O",0.922,4,2,14]
["S8615","Sodium dichloroacetate (DCA)","e8","L1300-29","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Cancer","Apoptosis related,Dehydrogenase,NKCC,ROS","Metabolism","Sodium dichloroacetate (DCA, Dichloroacetic acid, bichloroacetic acid, BCA), a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress Na+-K+-2Cl- cotransporter and a mitochondrial potassium-ion channel axis. Sodium dichloroacetate increases reactive oxygen species (ROS) generation, triggers apoptosis in cancer cells, and inhibits tumor growth.",150.92,"2156-56-1",30,198.78,30,198.78,"http://selleckchem.com/products/sodium-dichloroacetate-dca.html","C2HCl2O2.Na","sodium salt","Dichloroacetic acid, bichloroacetic acid, BCA","[Na]OC(=O)C(Cl)Cl",1.081,2,0,2]
["S8637","Ipragliflozin (ASP1941)","f8","L1300-29","in 10mM DMSO","marketed in Japan",null,null,"Endocrinology/Metabolic Disease","SGLT","GPCR & G Protein","Ipragliflozin (ASP1941) is a highly selective sodium-glucose cotransporter 2 (SGLT2) inhibitor with an IC50 value of 7.4 nM for hSGLT2 and a 254-fold selectivity versus SGLT1.",404.45,"761423-87-4",80,197.8,"<1",0,"http://selleckchem.com/products/ipragliflozin-asp-1941.html","C21H21FOS","free base","N/A","OCC1OC(C(O)C(O)C1O)C2=CC(=C(F)C=C2)CC3=CC4=C(S3)C=CC=C4",2.35,1,4,4]
["S8726","Anlotinib (AL3818) dihydrochloride","g8","L1300-29","in 10mM DMSO","CFDA",null,null,"Cancer/Gastroenterology/Respiratory Disease","VEGFR","Protein Tyrosine Kinase","Anlotinib (AL3818) is a highly potent and selective VEGFR2 inhibitor with IC50 less than 1 nM. It has broad-spectrum antitumor potential in clinical trials. Please use saline solution rather than PBS for dilutions. PBS may cause precipitation.",480.36,"1360460-82-7",96,199.85,96,199.85,"http://selleckchem.com/products/anlotinib-al3818.html","C23H22FN3O3.2HCl","dihydrochloride","N/A","Cl.Cl.COC1=C(OCC2(N)CC2)C=C3N=CC=C(OC4=C(F)C5=C([NH]C(=C5)C)C=C4)C3=C1",4.469,4,2,6]
["S8752","leniolisib (CDZ 173)","h8","L1300-29","in 10mM DMSO","FDA,NDC",null,"217759 ","Inflammation/Immunology","PI3K","PI3K/Akt/mTOR","Leniolisib (CDZ 173) is a potent PI3Kδ selective inhibitor with biochemical IC50 values of 0.244, 0.424, 2.23 and 0.011 μM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively.",450.46,"1354690-24-6",90,199.8,"<1",0,"http://www.selleckchem.com/products/leniolisib-cdz-173.html","C21H25F3N6O2","Free Base","N/A","CCC(=O)N1CCC(C1)NC2=NC=NC3=C2CN(CC3)C4=CC(=C(OC)N=C4)C(F)(F)F",2.65,5,1,6]
["S8757","Ripretinib (DCC-2618)","a9","L1300-29","in 10mM DMSO","FDA, NDC",null,213973,"Cancer","c-Kit,PDGFR","Protein Tyrosine Kinase","DCC-2618 is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of the tumor-associated antigens (TAA) mast/stem cell factor receptor (SCFR) Kit (c-Kit) and PDGFR-alpha, with IC50 values of 4 nM, 8 nM, 18 nM, 5 nM and 14 nM for WT Kit (c-Kit), V654A Kit (c-Kit), T670I Kit (c-Kit), D816H Kit (c-Kit) and D816V Kit (c-Kit), respectively.",510.36,"1442472-39-0",100,195.94,"<1",0,"http://www.selleckchem.com/products/ripretinib-dcc-2618.html","C24H21BrFN5O2","Free Base","N/A","CCN1C(=O)C(=CC2=C1C=C(NC)N=C2)C3=C(Br)C=C(F)C(=C3)NC(=O)NC4=CC=CC=C4",4.129,3,3,5]
["S8765","Abrocitinib (PF-04965842)","b9","L1300-29","in 10mM DMSO","EMA; FDA; NDC; PMDA ; DMF",null,213871,"Inflammation/Immunology","JAK","JAK/STAT","Abrocitinib (PF-04965842) is a potent JAK1 inhibitor with IC50s of 29 nM, 803 nM, > 10 000 nM and 1250 nM for JAK1, JAK2, JAK3 and tyrosine kinase (TYK) 2, respectively.",323.41,"1622902-68-4",65,200.98,"<1",0,"http://www.selleck.cn/products/pf-04965842.html","C14H21N5O2S","free base","N/A","CCC[S](=O)(=O)NC1CC(C1)N(C)C2=C3C=C[NH]C3=NC=N2",1.101,4,2,6]
["S8791","Zanubrutinib (BGB-3111)","c9","L1300-29","in 10mM DMSO","FDA, NDC, CFDA",null,213217,"Cancer","BTK","Protein Tyrosine Kinase","Zanubrutinib (BGB-3111) is a potent, specific and irreversible BTK inhibitor that has been shown to have a lower off-target inhibitory activity on other kinases, including ITK, JAK3 and EGFR.",471.55,"1691249-45-2",94,199.34,"<1",0,"http://www.selleck.cn/products/zanubrutini-bgb-3111.html","C27H29N5O3","Free Base","N/A","NC(=O)C1=C2NCCC(C3CCN(CC3)C(=O)C=C)[N]2N=C1C4=CC=C(OC5=CC=CC=C5)C=C4",3.478,4,2,6]
["S8817","Almonertinib (HS-10296)","d9","L1300-29","in 10mM DMSO","CFDA",null,null,"Cancer","EGFR","Protein Tyrosine Kinase","Almonertinib (Aumolertinib, HS-10296, Ameile) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR.",525.64,"1899921-05-1",100,190.24,"<1",0,"http://www.selleck.cn/products/hs-10296.html","C30H35N7O2","Free Base","Aumolertinib, Ameile","COC1=C(NC2=NC(=CC=N2)C3=C[N](C4CC4)C5=C3C=CC=C5)C=C(NC(=O)C=C)C(=C1)N(C)CCN(C)C",5.16,4,2,11]
["S8871","Omadacycline tosylate","e9","L1300-29","in 10mM DMSO","FDA",null,"209816,209817","Infection","Antibiotics,Bacterial","Microbiology","Omadacycline tosylate(PTK 0796 tosylate,Amadacycline tosylate) is a first-in-class aminomethylcycline antibiotic, demonstrating antimicrobial activity in vitro against a range of Gram-positive and Gram-negative aerobes and some anaerobic bacteria.",728.85,"1075240-43-5",100,137.2,100,137.2,"http://www.selleck.cn/products/omadacycline-tosylate.html","C36H48N4O10S","tosylate","PTK 0796 tosylate,Amadacycline tosylate","CN(C)C1C2CC3CC4=C(C=C(CNCC(C)(C)C)C(=C4C(=O)C3=C(O)C2(O)C(=O)C(=C1O)C(N)=O)O)N(C)C.CC5=CC=C(C=C5)[S](O)(=O)=O",2.749,3,5,8]
["S8873","Letermovir (AIC246)","f9","L1300-29","in 10mM DMSO","FDA,EMA,NDC,PMDA",null,"209939,209940","Infection","CMV","Microbiology","Letermovir (AIC246, MK-8228) is a novel anti-CMV compound which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors.",572.55,"917389-32-3",100,174.66,"<1",0,"http://www.selleck.cn/products/letermovir.html","C29H28F4N4O4","free base","MK-8228","COC1=CC(=CC=C1)N2CCN(CC2)C3=NC4=C(C=CC=C4F)C(CC(O)=O)N3C5=CC(=CC=C5OC)C(F)(F)F",5.451,4,0,8]
["S9001","Malic acid","g9","L1300-29","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010",null,"Cardiovascular Disease/Psychotic disorders","Others","Others","Malic acid (Hydroxybutanedioic acid, 2-Hydroxysuccinic acid) is a common, naturally occurring ingredient in many foods. It is the main acid found in apples and other fruits.",134.09,"6915-15-7",27,201.36,0,0,"https://www.selleckchem.com/products/malic-acid.html","C4H6O5","free base","Hydroxybutanedioic acid, 2-Hydroxysuccinic acid","OC(CC(O)=O)C(O)=O",-1.012,2,1,3]
["S9002","L-Fucose","h9","L1300-29","in 10mM DMSO",null,"BP2018",null,"Cancer/Immunology","Others","Others","Fucose (6-Deoxy-L-Galactose, L-fucopyranose) is found on N-linked glycans on the mammalian, insect and plant cell surface. L-Fucose is claimed to have application in cosmetics, pharmaceuticals, and dietary supplements.",164.16,"2438-80-4",33,201.03,0,0,"https://www.selleckchem.com/products/l-fucose.html","C6H12O5","free base","6-Deoxy-L-Galactose, L-fucopyranose","CC(O)C(O)C(O)C(O)C=O",-1.903,1,4,4]
["S9003","(R)-(-)-Mandelic acid","a10","L1300-29","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.2",null,"Others","Others","Others","(R)-(-)-Mandelic acid is a synthetic intermediate useful for pharmaceutical synthesis.",152.15,"611-71-2",30,197.18,0,0,"https://www.selleckchem.com/products/mandelic-acid.html","C8H8O3","free base","(R)-a-Hydroxy-benzeneacetic acid; (R)-2-Hydroxy-2-phenylacetic acid; (R)-2-Phenylglycolic acid","OC(C(O)=O)C1=CC=CC=C1",0.842,1,1,2]
["S9007","2'-deoxyguanosine","b10","L1300-29","in 10mM DMSO","DMF",null,null,"Others","Others","Others","2'-deoxyguanosine is a kind of purine nucleoside.",267.24,"961-07-9",53,198.32,0,0,"https://www.selleckchem.com/products/2-deoxyguanosine-monohydrate.html","C10H13N5O4","free base","2'-Deoxy-D-guanosine","NC1=NC2=C(N=C[N]2C3CC(O)C(CO)O3)C(=O)N1",-1.613,4,4,2]
["S9032","Sanguinarine","c10","L1300-29","in 10mM DMSO","NDC",null,null,"Cancer/Infection","Immunology & Inflammation related","Immunology & Inflammation","Sanguinarine (Pseudochelerythrine, Sanguinarin, Sanguinarium), a benzophenanthridine alkaloid known as an anti-inflammatory agent, is a potent inhibitor of NF-κB activation.",332.33,"2447-54-3",44,132.4,0,0,"https://www.selleckchem.com/products/sanguinarine.html","C20H14NO4","free base","Pseudochelerythrine, Sanguinarin, Sanguinarium","C[N+]1=CC2=C3OCOC3=CC=C2C4=C1C5=CC6=C(OCO6)C=C5C=C4",3.987,4,0,0]
["S9042","Wedelolactone","d10","L1300-29","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cancer/Inflammation","Caspase,IκB/IKK","NF-κB","Wedelolactone, a medicinal plant-derived natural compound, is an inhibitor of IKK that is critical for activation of NF-κB by mediating phosphorylation and degradation of IκBα. Wedelolactone is also an inhibitor of caspase-11.",314.25,"524-12-9",63,200.48,0,0,"https://www.selleckchem.com/products/wedelolactone.html","C16H10O7","free base","FW73945","COC1=CC2=C(C(=C1)O)C3=C(C(=O)O2)C4=C(O3)C=C(O)C(=C4)O",2.803,4,3,1]
["S9046","Berberine","e10","L1300-29","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,CP2005,KP Ⅹ,EP9.1,JP17,BP2017",null,"Infection/Parasitology","Bacterial","Microbiology","Berberine (Umbellatine), an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic.",336.36,"2086-83-1",45,133.78,0,0,"https://www.selleckchem.com/products/berberine.html","C20H18NO4","free base","Umbellatine","COC1=C(OC)C2=C(C=C1)C=C3C4=C(CC[N+]3=C2)C=C5OCOC5=C4",3.962,4,0,2]
["S9063","Harringtonine","f10","L1300-29","in 10mM DMSO","CFDA",null,null,"Cancer","Antiviral","Microbiology","Harringtonine is a natural cephalotaxine alkaloid that inhibits protein biosynthesis. It also exhibits antiviral and anticancer activities.",531.59,"26833-85-2",10,18.81,0,0,"https://www.selleckchem.com/products/harringtonine.html","C28H37NO9","free base","FH15975","COC(=O)CC(O)(CCC(C)(C)O)C(=O)OC1C2C3=CC4=C(OCO4)C=C3CCN5CCCC25C=C1OC",1.961,7,0,10]
["S9101","Ingenol","g10","L1300-29","in 10mM DMSO","FDA",null,null,"Cancer","PKC","Cytoskeletal Signaling","Ingenol, a plant-derived diterpenoid, is a weak PKC activator and possesses important anticancer activity.",348.43,"30220-46-3",69,198.03,0,0,"https://www.selleckchem.com/products/ingenol.html","C20H28O5","free base",0,"CC1CC2C(C3C=C(CO)C(O)C4(O)C(O)C(=CC14C3=O)C)C2(C)C",0.543,1,3,1]
["S9140","Pulegone","h10","L1300-29","in 10mM DMSO",null,"BP2019;EP9.2",null,"Parasite","TRP Channel","Transmembrane Transporters","Pulegone, a naturally occurring organic compound, is a fragrance and flavour ingredient.pulegone stimulates both TRPM8 and TRPA1 channel in chicken sensory neurons and suppresses the former but not the latter at high concentrations.",152.23,"89-82-7",0,"The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,"https://www.selleckchem.com/products/pulegone.html","C10H16O","free base",0,"CC1CCC(=C(C)C)C(=O)C1",2.891,1,0,0]
["S9141","Berbamine","a11","L1300-29","in 10mM DMSO","CFDA",null,null,"Hematology","Apoptosis related,Bcr-Abl,CaMK,NF-κB","Angiogenesis","Berbamine (BA), a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan), is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF-κB. Berbamine (BA) induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca²⁺/calmodulin-dependent protein kinase II (CaMKII).",608.72,"478-61-5",100,164.28,0,0,"https://www.selleckchem.com/products/berbamine.html","C37H40N2O6","free base","BA, BBM","COC1=C2OC3=C4C(CC5=CC=C(O)C(=C5)OC6=CC=C(CC7N(C)CCC(=C1)C7=C2)C=C6)N(C)CCC4=CC(=C3OC)OC",6.992,5,1,3]
["S9142","Sparteine","b11","L1300-29","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Sodium Channel","Transmembrane Transporters","Sparteine, which could be extracted from scotch broom, is a sodium channel blocker and a class 1a antiarrhythmic agent.",234.38,"492-08-0",0,"The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,"https://www.selleckchem.com/products/sparteine.html","C15H26N2","free base",0,"C1CCN2CC3CC(CN4CCCCC34)C2C1",2.363,0,0,0]
["S9143","Ammonium Glycyrrhizate","c11","L1300-29","in 10mM DMSO",null,"USP42-NF37;EP9.2",null,"Cancer/Immunology/Inflammation","Others","Others","Ammonium glycyrrhizate (Glycamil, Glycyrram) is an ammonium salt extract isolated from licorice root and is commonly used as a flavoring agent and is also used in fragrances, and skin and hair care products.",839.96,"53956-04-0",100,119.05,0,0,"https://www.selleckchem.com/products/ammonium-glycyrrhizate.html","C42H65NO16","free base","Glycamil, Glycyrram","N.CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O)OC6OC(C(O)C(O)C6OC7OC(C(O)C(O)C7O)C(O)=O)C(O)=O",-0.915,8,5,7]
["S9179","Catharanthine hemitartrate","d11","L1300-29","in 10mM DMSO","DMF",null,null,"Cancer/Cardiovascular Disease","AChR","Neuronal Signaling","Catharanthine hemitartrate is the starting material for the synthesis of the antitumor drugs vinblastine and vincristine.",822.94,"4168-17-6",97,199.38,0,0,"https://www.selleckchem.com/products/catharanthine-hemitartrate.html","C46H54N4O10","free base",0,"CCC1=CC2CN3CCC4=C([NH]C5=C4C=CC=C5)C(C2)(C13)C(=O)OC.OC(C(O)C(O)=O)C(O)=O",-0.822,4,3,6]
["S9193","Aristolochic acid A","e11","L1300-29","in 10mM DMSO","PMDA","JP17",null,"Others","AP-1,NF-κB","NF-κB","Aristolochic acid A (Aristolochic Acid I, Aristolochin, Aristolochine, TR 1736) is a carcinogenic, mutagenic, and nephrotoxic agent extracted from the flowering plant family Aristolochiaceae.Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and nuclear factor-κB (NF-κB) activities.",341.27,"313-67-7",6,17.58,-1,0,"http://www.selleckchem.com/products/aristolochic-acid-a.html","C17H11NO7","Free Base","Aristolochic Acid I, Aristolochin, Aristolochine, TR 1736","COC1=CC=CC2=C3C4=C(OCO4)C=C(C(O)=O)C3=C(C=C12)[N+]([O-])=O",2.922,4,0,3]
["S9212","Melamine","f11","L1300-29","in 10mM DMSO","DMF","USP42-NF37,EP9.2,BP2017",null,"Others","Others","Others","Melamine (Cyanuramide, Cyanurotriamide) is a widely-used intermediate, mainly employed as a raw material for producing melamine resin and is a chemical most often found in plastic materials.",126.12,"108-78-1",25,198.22,0,0,"https://www.selleckchem.com/products/melamine.html","C3H6N6","free base","Cyanuramide, Cyanurotriamide","NC1=NC(=NC(=N1)N)N",-0.732,3,3,0]
["S9222","Dipotassium glycyrrhizinate","g11","L1300-29","in 10mM DMSO","NDC,PMDA","BP2017,CP2005",null,"Cardiovascular Disease/Endocrinology/Infection","Immunology & Inflammation related","Immunology & Inflammation","Glycyrrhizinate dipotassium (Neubormitin) is a widely used anti-inflammatory agent isolated from the licorice root.",899.11,"68797-35-3",25,27.81,0,0,"https://www.selleckchem.com/products/dipotassium-glycyrrhizinate.html","C42H60K2O16","free base","Neubormitin","[K+].[K+].CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O)OC6OC(C(O)C(O)C6OC7OC(C(O)C(O)C7O)C([O-])=O)C([O-])=O",-0.531,6,5,7]
["S9227","Sinensetin","h11","L1300-29","in 10mM DMSO",null,"BP2019;EP9.2",null,"Angiology/Inflammation","Others","Others","Sinensetin (Pedalitin Permethyl ether), a natural polymethoxylated flavone, has potent antiangiogenesis activity.",372.37,"2306-27-6",27,72.51,0,0,"https://www.selleckchem.com/products/sinensetin.html","C20H20O7","free base","Pedalitin Permethyl ether","COC1=CC=C(C=C1OC)C2=CC(=O)C3=C(O2)C=C(OC)C(=C3OC)OC",3.054,7,0,6]
["S9240","Isofraxidin","a2","L1300-30","in 10mM DMSO",null,"CP2005",null,"Cancer","Immunology & Inflammation related","Immunology & Inflammation","Isofraxidin (6,8-Dimethoxyumbelliferone), a bioactive coumarin compound isolated from the functional foods Siberian ginseng and Apium graveolens, is an anti-bacterial, anti-oxidant, and anti-inflammatory agent.",222.19,"486-21-5",44,198.03,0,0,"https://www.selleckchem.com/products/isofraxidin.html","C11H10O5","free base","6,8-Dimethoxyumbelliferone","COC1=CC2=C(OC(=O)C=C2)C(=C1O)OC",1.625,4,1,2]
["S9249","Securinine","b2","L1300-30","in 10mM DMSO","CFDA",null,null,"Neurological Disease","GABA Receptor","Neuronal Signaling","Securinine, a major natural alkaloid product from the root of the plant Securinega suffruticosa, acts as a γ-amino butyric acid (GABA) receptor antagonist.",217.26,"5610-40-2",44,202.52,0,0,"https://www.selleckchem.com/products/securinine.html","C13H15NO2","free base",0,"O=C1OC23CC(C=CC2=C1)N4CCCCC34",1.449,2,0,0]
["S9252","Corydaline","c2","L1300-30","in 10mM DMSO",null,"EP10.4",null,"Neurological Disease","AChR","Neuronal Signaling","Corydaline is a bioactive alkaloid with various anti-acetylcholinesterase, anti-allergic, and anti-nociceptive activities found in the medicinal herb Corydalis Tubers.",369.45,"518-69-4",74,200.3,0,0,"https://www.selleckchem.com/products/corydaline.html","C22H27NO4","free base",0,"COC1=CC2=C(C=C1OC)C3C(C)C4=C(CN3CC2)C(=C(OC)C=C4)OC",3.918,4,0,4]
["S9263","3-n-Butylphathlide","d2","L1300-30","in 10mM DMSO","CFDA",null,null,"Cardiovascular Disease","Others","Others","3-n-Butylphathlide, initially isolated from the seeds of Apium graveolens Linn., has shown significant neuroprotective effects.",190.24,"6066-49-5",0,"The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,"https://www.selleckchem.com/products/3-n-butylphathlide.html","C12H14O2","free base",0,"CCCCC1OC(=O)C2=C1C=CC=C2",3.252,2,0,3]
["S9311","Germacrone","e2","L1300-30","in 10mM DMSO",null,"CP2005",null,"Respiratory Disease","Immunology & Inflammation related","Immunology & Inflammation","Germacrone, a major activity component found in Curcuma zedoaria oil product, shows anti-inflammatory, antiandrogenic, and antimicrobial activities.",218.33,"6902-91-6",44,201.53,0,0,"https://www.selleckchem.com/products/germacrone.html","C15H22O","free base",0,"CC(C)=C1C\\C=C(C)\\CC/C=C(C)/CC1=O",4.468,1,0,0]
["S9321","Topotecan","f2","L1300-30","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia,IP2010,EP","200199","Cancer/Respiratory Disease","Topoisomerase","DNA Damage/DNA Repair","Topotecan(NSC609699,Nogitecan,SKFS 104864A) is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.",421.45,"123948-87-8",84,199.31,0,0,"https://www.selleckchem.com/products/topotecan.html","C23H23N3O5","free base","NSC609699,Nogitecan,SKFS 104864A","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC(=C(CN(C)C)C5=C4)O)C2=O",1.577,4,1,3]
["S9326","Scopolamine","g2","L1300-30","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","CP2005,USP42-NF37,EP9.2,JP17,IP2010","078830","Cardiovascular Disease/Neurological Disease","AChR","Neuronal Signaling","Scopolamine (Skopolamin) is a tropane alkaloid derived from plants of the nightshade family, specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic and antivertigo properties.",303.35,"51-34-3",0,"The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,"https://www.selleckchem.com/products/scopolamine.html","C17H21NO4","free base","Skopolamin","CN1C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",0.823,3,1,5]
["S9327","Carboprost","h2","L1300-30","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia","017989","Others","Prostaglandin Receptor","GPCR & G Protein","Carboprost is a synthetic prostaglandin analogue of PGF2α with oxytocic properties.",368.51,"35700-23-3",73,198.1,-1,-2.71,"https://www.selleckchem.com/products/carboprost.html","C21H36O5","free base",0,"CCCCCC(C)(O)/C=C/C1C(O)CC(O)C1C\\C=C/CCCC(O)=O",3.188,1,2,12]
["S9329","Orcinol","a3","L1300-30","in 10mM DMSO",null,"BP2010",null,"Others","Others","Others","Orcinol (5-Methylresorcinol; 3,5-ToluenediolOrcin; 5-Methyl-1,3-benzenediol; 3,5-Dihydroxytoluene), occurs in many species of lichens including Roccella tinctoria and Lecanora, exhibits antimutagenic, antioxidant, antibacterial, radical-scavenging effects.",124.14,"504-15-4",24,193.33,0,0,"https://www.selleckchem.com/products/orcinol.html","C7H8O2",0,"5-Methylresorcinol; 3,5-ToluenediolOrcin; 5-Methyl-1,3-benzenediol; 3,5-Dihydroxytoluene","CC1=CC(=CC(=C1)O)O",1.832,0,2,0]
["S9338","Octyl gallate","b3","L1300-30","in 10mM DMSO",null,"BP2019;EP9.2",null,"Infection","Others","Microbiology","Octyl gallate (Progallin O, n-Ocyl gallate, Stabilizer GA-8, Gallic acid octyl ester), a widely used food additive, shows antimicrobial and antioxidant activity.",282.33,"1034-01-1",56,198.35,0,0,"https://www.selleckchem.com/products/octyl-gallate.html","C15H22O5","free base","Progallin O, n-Ocyl gallate, Stabilizer GA-8, Gallic acid octyl ester","CCCCCCCCOC(=O)C1=CC(=C(O)C(=C1)O)O",4.112,2,3,9]
["S9346","1-Indanone","c3","L1300-30","in 10mM DMSO","DMF",null,null,"Others","Others","Others","1-Indanone (Indan-1-one, Alpha-Indanone) is an oxidation product of Indan, a component of fuels, solvents, and varnishes. It is part of the steroid hormone biosynthesis, and arachidonic acid metabolism pathways.",132.16,"83-33-0",26,196.73,-1,0,"http://www.selleckchem.com/products/1-indanone.html","C9H8O","Free Base","Indan-1-one, Alpha-Indanone","O=C1CCC2=C1C=CC=C2",1.895,1,0,0]
["S9349","D-(+)-Raffinose pentahydrate","d3","L1300-30","in 10mM DMSO",null,"BP2019",null,"Cardiovascular Disease/Immunology","Others","Others","Raffinose is a trisaccharide composed of galactose, glucose, and fructose.",594.51,"17629-30-0",100,168.2,0,0,"https://www.selleckchem.com/products/d-r-affinose-pentahydrate.html","C18H42O21","free base",0,"O.O.O.O.O.OCC1OC(OCC2OC(OC3(CO)OC(CO)C(O)C3O)C(O)C(O)C2O)C(O)C(O)C1O",-7.094,5,11,8]
["S9351","2'-Deoxyadenosine monohydrate","e3","L1300-30","in 10mM DMSO","DMF",null,null,"Endocrinology","Others","Others","2'-Deoxyadenosine may be used as an energy source under energy stress conditions and to affect cAMP levels.",269.26,"16373-93-6",54,200.55,0,0,"https://www.selleckchem.com/products/2-deoxyadenosine-monohydrate.html","C10H15N5O4","free base",0,"O.NC1=NC=NC2=C1N=C[N]2C3CC(O)C(CO)O3",-1.322,4,3,2]
["S9354","Oxalic acid","f3","L1300-30","in 10mM DMSO","NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010",null,"Others","Others","Others","Oxalic acid (Ethanedioic acid, Wood bleach) is a strong dicarboxylic acid occurring in many plants and vegetables.",90.03,"144-62-7",18,199.92,0,0,"https://www.selleckchem.com/products/oxalic-acid.html","C2H2O4","free base","Ethanedioic acid, Wood bleach","OC(=O)C(O)=O",-0.429,2,0,1]
["S9368","ADP","g3","L1300-30","in 10mM DMSO","DMF",null,null,"Others","Others","Others","ADP (Adenosine diphosphate, adenosine pyrophosphate, Adenosine 5'-diphosphate) is an important organic compound in metabolism and is essential to the flow of energy in living cells.",427.2,"58-64-0",6,14.04,0,0,"https://www.selleckchem.com/products/adp.html","C10H15N5O10P2","free base","Adenosine diphosphate, adenosine pyrophosphate, Adenosine 5'-diphosphate","NC1=NC=NC2=C1N=C[N]2C3OC(CO[P](O)(=O)O[P](O)(O)=O)C(O)C3O",-2.239,6,3,6]
["S9373","Neryl acetate","h3","L1300-30","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Others","Others","Neryl acetate (Nerol, Acetic acid neryl ester, cis-Geranyl), a chemical compound found in citrus oils, is a flavouring agent.",196.29,"141-12-8",0,"The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,"https://www.selleckchem.com/products/neryl-acetate.html","C12H20O2","free base","Nerol acetate, Acetic acid neryl ester, cis-Geranyl acetate","CC(=O)OC\\C=C(C)/CCC=C(C)C",3.313,2,0,6]
["S9380","5,7-Dihydroxy-4-methylcoumarin","a4","L1300-30","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Others","Others","5,7-Dihydroxy-4-methylcoumarin may be used for pharmaceutical synthesis.",192.17,"2107-76-8",38,197.74,0,0,"https://www.selleckchem.com/products/dihydroxy-4-methylcoumarin.html","C10H8O4","free base",0,"CC1=CC(=O)OC2=C1C(=CC(=C2)O)O",1.862,2,2,0]
["S9382","Thymine","b4","L1300-30","in 10mM DMSO",null,"BP2019;EP9.2;IP2010",null,"Others","DNA/RNA Synthesis","DNA Damage/DNA Repair","Thymine (5-methyluracil) is one of the four nucleobases in the nucleic acid of DNA.",126.11,"65-71-4",25,198.23,0,0,"https://www.selleckchem.com/products/thymine.html","C5H6N2O2","free base","5-methyluracil","CC1=CNC(=O)NC1=O",-0.566,2,2,0]
["S9383","Methyl palmitate","c4","L1300-30","in 10mM DMSO",null,"USP42-NF37 ;BP2019;EP9.2;IP2010",null,"Others","Others","Others","Methyl palmitate (Methyl hexadecanoate, Palmitic acid methyl ester), a kind of fatty acid methyl ester, could be found in many plants and possesses acaricidal activity.",270.45,"112-39-0",0,"The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,"https://www.selleckchem.com/products/methyl-palmitate.html","C17H34O2","free base","Methyl hexadecanoate, Palmitic acid methyl ester","CCCCCCCCCCCCCCCC(=O)OC",6.618,2,0,15]
["S9400","Rhynchophylline","d4","L1300-30","in 10mM DMSO",null,"BP2019;EP9.2",null,"Inflammation/Neurological Disease","Calcium Channel","Transmembrane Transporters","Rhynchophylline (Mitrinermine), an active component isolated from species of the genus Uncaria, acts as a calcium channel blocker and is widely used in traditional Chinese medicine mainly for treating ailments of central nervous and cardiovascular systems, such as lightheadedness, convulsions, numbness, and hypertension.",384.47,"76-66-4",76,197.68,0,0,"https://www.selleckchem.com/products/rhynchophylline.html","C22H28N2O4","free base","Mitrinermine","CCC1CN2CCC3(C2CC1\\C(=C/OC)C(=O)OC)C(=O)NC4=CC=CC=C34",2.103,4,1,5]
["S9413","Yangonin","e4","L1300-30","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","Cannabinoid Receptor,Fungal","GPCR & G Protein","Yangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors.",258.27,"500-62-9",51,197.47,0,0,"https://www.selleckchem.com/products/yangonin.html","C15H14O4","free base","Y100550","COC1=CC=C(C=C1)/C=C/C2=CC(=CC(=O)O2)OC",2.211,4,0,4]
["S9451","Uridine 5'-monophosphate","f4","L1300-30","in 10mM DMSO","DMF",null,null,"Others","DNA/RNA Synthesis","DNA Damage/DNA Repair","Uridine 5'-monophosphate (Uridylic acid, 5'-Uridylic acid, Uridine phosphate, 5'-UMP, Uridine 5'-phosphoric acid) is a nucleotide that is used as a monomer in RNA.",324.18,"58-97-9",65,200.51,-1,0,"http://www.selleckchem.com/products/uridine-5-monophosphate.html","C9H13N2O9P","Free Base","Uridylic acid, 5'-Uridylic acid, Uridine phosphate, 5'-UMP, Uridine 5'-phosphoric acid","OC1C(O)C(OC1CO[P](O)(O)=O)N2C=CC(=O)NC2=O",-2.522,4,3,4]
["S9452","10-Undecenoic acid","g4","L1300-30","in 10mM DMSO","NDC, CFDA","Martindale the Extra Pharmacopoei, EP10.2, USP43-NF38, KP X, IP2010",null,"Others","Others","Others","10-Undecenoic acid, a natural or synthetic fungistatic fatty acid, is used for the preparation of active pharmaceutical ingredients, cosmetics, perfumes, antidandruff shampoos and antimicrobial powders.",184.28,"112-38-9","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/10-undecenoic-acid.html","C11H20O2","Free Base","N/A","OC(=O)CCCCCCCCC=C",3.721,1,0,9]
["S9454","Undecanoic acid","h4","L1300-30","in 10mM DMSO",null,"BP2019;EP9.2",null,"Infection","Others","Others","Undecanoic acid (Undecylic acid) is a medium chain length monocarboxylic acid that appears to be involved in the control of triacylglycerol synthesis.",186.29,"112-37-8","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/undecanoic-acid.html","C11H22O2","Free Base","Undecylic acid","CCCCCCCCCCC(O)=O",4.111,1,0,9]
["S9457","Phensuximide","a5","L1300-30","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","008855","Neurological Disease","cAMP/cGMP","Neuronal Signaling","Phensuximide is an orally active succinimide antiepileptic and anticonvulsant agent. Phensuximide inhibits cyclic AMP and cyclic GMP accumulation in depolarized brain tissue. Phensuximide can be used for the study of seizure and petit mal.",189.21,"86-34-0",38,200.84,-1,0,"N/A","C11H11NO2","Free Base","N/A","CN1C(=O)CC(C1=O)C2=CC=CC=C2",0.908,2,0,1]
["S9459","Mecamylamine Hydrochloride","c5","L1300-30","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","204054","Cardiovascular Disease","AChR","Neuronal Signaling","Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist. Mecamylamine hydrochloride is also a ganglionic blocker. Mecamylamine hydrochloride can across the blood-brain barrier. Mecamylamine hydrochloride can be used in the research of neuropsychiatric disorders, hypertension, antidepressant area.",203.75,"826-39-1",41,201.23,-1,0,"N/A","C11H21N · HCl","Hydrochloride","N/A","Cl.CNC1(C)C2CCC(C2)C1(C)C",2.565,0,1,1]
["S9460","Ethotoin","d5","L1300-30","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","010841","Neurological Disease","Sodium Channel","Transmembrane Transporters","Ethotoin (Peganone) is an orally active anticonvulsant agent used in epilepsy research. Ethotoin inhibits nerve impulses in the motor cortex by lowering sodium ion influx, limiting tetanic stimulation.",204.23,"86-35-1",41,200.75,-1,0,"N/A","C11H12N2O2","Free Base","N/A","CCN1C(=O)NC(C1=O)C2=CC=CC=C2",1.113,2,1,2]
["S9461","Benzonatate","e5","L1300-30","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","040587,040597,040627,040682,040749,040795,040851,081297,091133,091310,201209,202765,206948,210562,211518","Respiratory Disease","Sodium Channel","Transmembrane Transporters","Benzonatate(Benzononatine)  has sodium channel-blocking properties and local anesthetic effects on the respiratory stretch receptors due to a tetracaine-like metabolite.",603.74,"32760-16-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"https://www.selleckchem.com/products/benzonatate.html","(C2H4O)nC12H17NO2","Free Base","Benzononatine","CCCCNC1=CC=C(C=C1)C(=O)OCCOC",3.426,3,1,9]
["S9463","Demecarium Bromide","f5","L1300-30","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","011860","Ophthalmology","AChR","Neuronal Signaling","Demecarium Bromide (BC-48) is a potent cholinesterase inhibitor, with an apparent affinity (Kiapp) of 0.15 μM. Demecarium Bromide (BC-48) is used as a glaucoma agent.",716.59,"56-94-0",100,139.55,-1,0,"N/A","C32H52Br2N4O4","Bromide","N/A","[Br-].[Br-].CN(CCCCCCCCCCN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C)C(=O)OC2=CC=CC(=C2)[N+](C)(C)C",-0.615,4,0,17]
["S9466","Methenamine Hippurate","g5","L1300-30","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","076411,205661","Infection","Bacterial","Microbiology","Methenamine Hippurate is the hippurate salt form of methenamine, a prodrug and inactive weak base that is hydrolyzed to formaldehyde in acid urine.Methenamine Hippurate is the component of Hiprex drug which has antibacterial activity.",319.36,"5714-73-8",14,43.84,-1,0,"https://www.selleckchem.com/products/methenamine-hippurate.html","C15H21N5O3","Hippurate","N/A","OC(=O)CNC(=O)C1=CC=CC=C1.C2N3CN4CN2CN(C3)C4",-2.43,2,1,3]
["S9467","Thiothixene","h5","L1300-30","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","070600,070601,070602,070603,071093,071529,071530,071626,071627,071628,071884,071885,071886,071887,072200,211642","Psychotic disorders","Dopamine receptor & Adrenergic receptor","Neuronal Signaling","Thiothixene is an antipsychotic thioxanthene used for the management of schizophrenia. It has antagonistic effects on dopaminergic-receptor and alpha-adrenergic receptor.",443.63,"3313-26-6",5,11.27,-1,0,"N/A","C23H29N3O2S2","Free Base","N/A","CN1CCN(CC\\C=C/2C3=C(SC4=C2C=C(C=C4)[S](=O)(=O)N(C)C)C=CC=C3)CC1",3.533,2,0,5]
["S9469","Haloperidol Decanoate","a6","L1300-30","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","074811,074893,075176,075305,075393,075440,076463,205241,209101","Psychotic disorders","D2R","Neuronal Signaling","Haloperidol Decanoate is an antipsychotic drug used for the management of schizophrenia. It has antagonistic effects on dopamine 2 receptor.",530.11,"74050-97-8",100,188.64,-1,0,"N/A","C31H41ClFNO3","Decanoate","N/A","CCCCCCCCCC(=O)OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C3=CC=C(Cl)C=C3",8.127,3,0,16]
["S9470","Penbutolol Sulfate","b6","L1300-30","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","018976","Cardiovascular Disease","Adrenergic Receptor","GPCR & G Protein","Penbutolol sulfate ((-)-Terbuclomine) is an effective beta-adrenergic receptor blocker and diuretic that is used as an antihypertensive agent.",680.94,"38363-32-5",15,22.03,-1,0,"https://www.selleckchem.com/products/penbutolol-sulfate.html","C18H29NO2.1/2H2O4S","Sulfate","(-)-Terbuclomine","CC(C)(C)NCC(O)COC1=C(C=CC=C1)C2CCCC2.CC(C)(C)NCC(O)COC3=C(C=CC=C3)C4CCCC4.O[S](O)(=O)=O",6.536,2,4,14]
["S9472","Oxtriphylline","c6","L1300-30","in 10mM DMSO","FDA,DMF","USP42-NF37","087835,087866,088243","Immunology/Inflammation","PDE Inhibitor, Adenosine receptor, & Histone deacetylase","Metabolism","Oxtriphylline is a choline salt of theophylline with anti-asthmatic activity (bronchodilator). The theophylline, upon release, acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator.",283.33,"4499-40-5",15,52.94,-1,0,"N/A","C12H21N5O3","Free Base","N/A","CN1C(=O)N(C)C2=C([N-]C=N2)C1=O.C[N+](C)(C)CCO",-1.714,3,1,2]
["S9500","Valbenazine tosylate","d6","L1300-30","in 10mM DMSO","FDA",null,"209241","Neurological Disease","VMAT","Transmembrane Transporters","Valbenazine tosylate (NBI-98854) is the tosylate salt of valbenazine, a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no significant binding to VAMT1(Ki<10 μM).",762.97,"1639208-54-0",100,131.07,-1,-1.31,"https://www.selleckchem.com/products/valbenazine-tosylate.html","C38H54N2O10S2","free base","NBI-98854","COC1=C(OC)C=C2C3CC(OC(=O)C(N)C(C)C)C(CC(C)C)CN3CCC2=C1.CC4=CC=C(C=C4)[S](O)(=O)=O.CC5=CC=C(C=C5)[S](O)(=O)=O",7.062,4,1,10]
["S9502","Madecassic acid","e6","L1300-30","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cancer/Cardiovascular Disease/Psychotic disorders","COX,Immunology & Inflammation related,Interleukins,NF-κB,NOS,TNF-alpha","Immunology & Inflammation","Madecassic acid (Brahmic acid), a natural triterpene first isolated from C. asiatica, has diverse anti-inflammatory and anti-diabetic effects, blocking NF-κB activation in macrophages and causing by iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 inhibition.",504.7,"18449-41-7",100,198.13,-1,0,"http://www.selleckchem.com/products/madecassic-acid.html","C30H48O6","Free Base","Brahmic acid","CC1CCC2(CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(CO)C5C(O)CC34C)C2C1C)C(O)=O",3.265,1,4,2]
["S9507","(−)-Norepinephrine","f6","L1300-30","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.0,BP2016","040455,040462,040522,040859,203662,210839,211242,211359","Neurological Disease/Endocrinology","Adrenergic Receptor","Neuronal Signaling","(−)-Norepinephrine (Arterenol, Levarterenol, L-Noradrenaline) is a natural neurotransmitter and hormone. It is an agonist of adrenergic receptors with Ki values of 330, 56, and 740 nM for α1, α2, and β1 adrenoceptors, respectively.",169.18,"51-41-2",11,65.02,-1,0,"http://www.selleckchem.com/products/norepinephrine.html","C8H11NO3","Free Base","Arterenol, Levarterenol, L-Noradrenaline","NCC(O)C1=CC(=C(O)C=C1)O",-0.059,0,4,2]
["S9508","Brimonidine","g6","L1300-30","in 10mM DMSO","FDA,DMF,HMA,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","209158","Ophthalmology","Adrenergic Receptor","Neuronal Signaling","Brimonidine (Bromoxidine, UK 1430) is an alpha adrenergic receptor agonist (primarily alpha-2) and is used for the treatment of open-angle glaucoma or ocular hypertension to lower intraocular pressure.",292.13,"59803-98-4",26,89,-1,0,"http://www.selleckchem.com/products/brimonidine.html","C11H10BrN5","Free Base","Bromoxidine, UK 14304","BrC1=C(NC2=NCCN2)C=CC3=C1N=CC=N3",1.237,3,2,2]
["S9509","Tiapride Hydrochloride","h6","L1300-30","in 10mM DMSO","DMF,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,JP17,BP2017",null,"Neurological Disease/Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Tiapride is a drug that selectively blocks D2 and D3 dopamine receptors in the brain and is used to treat a variety of neurological and psychiatric disorders.",364.89,"51012-33-0",35,95.92,-1,0,"http://www.selleckchem.com/products/tiapride-hydrochloride.html","C15H25ClN2O4S","hydrochloride","N/A","Cl.CCN(CC)CCNC(=O)C1=CC(=CC=C1OC)[S](C)(=O)=O",1.766,4,1,8]
["S9510","Protriptyline hydrochloride","a7","L1300-30","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017,IP2010","078913,090462,202220","Psychotic disorders","5-HT Receptor","Neuronal Signaling","Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline. Protriptyline is a tricyclic secondary amine with antidepressant property which acts by inhibition of serotonin and norepinephrine reuptake.",299.84,"1225-55-4",60,200.11,-1,0,"http://www.selleckchem.com/products/protriptyline-hydrochloride.html","C19H22ClN","hydrochloride","N/A","Cl.CNCCCC1C2=C(C=CC=C2)C=CC3=C1C=CC=C3",4.423,0,1,4]
["S9552","Farrerol","b7","L1300-30","in 10mM DMSO",null,"CP2005",null,"Inflammation/Respiratory Disease","Others","Immunology & Inflammation","Farrerol, an important bioactive constituent of rhododendron, exhibits broad activities such as anti-oxidative and anti-inflammatory effects.",300.31,"24211-30-1",60,199.79,-1,0,"http://www.selleckchem.com/products/farrerol.html","C17H16O5","Free Base","N/A","CC1=C(O)C2=C(OC(CC2=O)C3=CC=C(O)C=C3)C(=C1O)C",3.346,2,3,1]
["S9560","Anisodamine Hydrobromide","c7","L1300-30","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Gastroenterology","AChR,Adrenergic Receptor,Anti-infection,Immunology & Inflammation related","Immunology & Inflammation","Anisodamine (6-Hydroxyhyoscyamine) is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs).",386.28,"55449-49-5",77,199.34,-1,0,"http://www.selleckchem.com/products/anisodamine-hydrobromide.html","C17H24BrNO4","Hydrobromide","6-Hydroxyhyoscyamine","Br.CN1C2CC(O)C1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",1.121,2,2,5]
["S9566","Bepridil hydrochloride","d7","L1300-30","in 10mM DMSO","FDA,DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia","019001,019002","Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Bepridil hydrochloride(CERM 1978) is an anti-anginal drug classified as a calcium channel blocker. It also blocks multiple other ion channels, including sodium and potassium channels.",421.02,"74764-40-2",41,97.38,-1,0,"http://www.selleckchem.com/products/bepridil-hydrochloride.html","C24H37ClN2O2","hydrochloride","CERM 1978","O.Cl.CC(C)COCC(CN(CC1=CC=CC=C1)C2=CC=CC=C2)N3CCCC3",5.439,1,0,10]
["S9567","Indinavir Sulfate","e7","L1300-30","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,Ph.Int_6th,BP2017","020685","Infection","COVID-19,HIV Protease","Microbiology","Indinavir sulfate (Crixivan, L-735524, MK-639) is a specific and potent inhibitor of HIV-1 protease and is widely used in the treatment of AIDS.",711.87,"157810-81-6",100,140.48,-1,0,"http://www.selleckchem.com/products/indinavir-sulfate.html","C36H49N5O8S","Sulfate","Crixivan, L-735524, MK-639","CC(C)(C)NC(=O)C1CN(CCN1CC(O)CC(CC2=CC=CC=C2)C(=O)NC3C(O)CC4=C3C=CC=C4)CC5=CN=CC=C5.O[S](O)(=O)=O",2.475,3,4,12]
["S9568","Sapropterin Dihydrochloride","f7","L1300-30","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","207200,207685,209452","Metabolic Disease","Hydroxylase","Metabolism","Sapropterin Dihydrochloride (Tetrahydrobiopterin, R-THBP), a synthetic preparation of the dihydrochloride salt of naturally occurring tetrahydrobiopterin (BH4), is a phenylalanine hydroxylase activator.",314.17,"69056-38-8",63,200.53,-1,0,"http://www.selleckchem.com/products/sapropterin-dihydrochloride.html","C9H17Cl2N5O3","Dihydrochloride","Tetrahydrobiopterin Dihydrochloride, R-THBP Dihydrochloride","Cl.Cl.CC(O)C(O)C1CNC2=C(N1)C(=O)NC(=N2)N",-1.572,2,6,2]
["S2934","Ensartinib (X-396) dihydrochloride","g7","L1300-30","in 10mM DMSO","FDA",null,"218171","Cancer","ALK","Angiogenesis","Ensartinib (X-396) is a potent new-generation ALK inhibitor with high activity against a broad range of known crizotinib-resistant ALK mutations and CNS metastases. It potently inhibits both wild-type ALK and ALK variants (F1174, C1156Y, L1196M, S1206R, T1151, and G1202R mutants) with in vitro IC50s of <4 nM.",634.36,"2137030-98-7",100,157.64,27,42.56,"http://www.selleck.cn/products/ensartinib-dihydrochloride.html","C26H29Cl4FN6O3","Dihydrochloride","N/A","Cl.Cl.CC1CN(CC(C)N1)C(=O)C2=CC=C(NC(=O)C3=NN=C(N)C(=C3)OC(C)C4=C(Cl)C(=CC=C4Cl)F)C=C2",5.051,5,3,6]
["S4421","Josamycin","h7","L1300-30","in 10mM DMSO","CFDA,PMDA","Martindale the Extra Pharmacopoei,EP8.8,KP Ⅹ,JP17,BP2017",null,"Infection","Antibiotics","Microbiology","Josamycin (EN-141, Kitasamycin A3, Leucomycin A3, Turimycin A5) is a macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.",827.99,"16846-24-5",100,120.77,"<1",0,"http://www.selleck.cn/products/josamycin.html","C42H69NO15","Free Base","EN-141, Kitasamycin A3, Leucomycin A3, Turimycin A5","COC1C(CC(=O)OC(C)C/C=C/C=C/C(O)C(C)CC(CC=O)C1OC2OC(C)C(OC3CC(C)(O)C(OC(=O)CC(C)C)C(C)O3)C(C2O)N(C)C)OC(C)=O",2.957,12,2,14]
["S5856","Trifluoperazine","a8","L1300-30","in 10mM DMSO","FDA,CFDA,DMF,NDC","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,BP2017,IP2010","089893","Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Trifluoperazine (NSC-17474, RP-7623, SKF-5019) is an FDA-approved antipsychotic drug for schizophrenia. It is an inhibitor of calmodulin (CaM) and Dopamine D2 receptor with an IC50 value of 1.2 nM for D2 receptor.",407.5,"117-89-5",0,"The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,"http://www.selleck.cn/products/trifluoperazine.html","C21H24F3N3S","Free Base","NSC-17474, RP-7623, SKF-5019","CN1CCN(CCCN2C3=C(SC4=C2C=C(C=C4)C(F)(F)F)C=CC=C3)CC1",4.975,0,0,5]
["S5934","(-)-Fenchone","b8","L1300-30","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei,EP8.8,BP2020",null,"Others","Others","Others","Fenchone is a constituent of absinthe and the essential oil of fennel. It is used as a flavor in foods and in perfumery.",152.23,"7787-20-4",0,"The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,"http://www.selleck.cn/products/fenchone.html","C10H16O","Free Base","N/A","CC1(C)C2CCC(C)(C2)C1=O",2.497,1,0,0]
["S6490","Vadadustat","c8","L1300-30","in 10mM DMSO","FDA, EMA, NDC, PMDA",null,215192,"Cardiovascular Disease","HIF","Angiogenesis","Vadadustat (AKB-6548, B-506, PG-1016548) is a novel, titratable, oral HIF-PH inhibitor.",306.7,"1000025-07-9",61,198.89,"<1",0,"http://www.selleck.cn/products/vadadustat.html","C14H11ClN2O4","Free Base","AKB-6548, B-506, PG-1016548","OC(=O)CNC(=O)C1=NC=C(C=C1O)C2=CC=CC(=C2)Cl",1.738,3,2,4]
["S6581","Fosamprenavir calcium salt","d8","L1300-30","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale the Extra Pharmacopoei","204024 ,204060 ,204130","Infection","HIV Protease","Microbiology","Fosamprenavir(GW433908G) is a pro-drug of the protease inhibitor and antiretroviral drug amprenavir. It is used for the treatment of HIV-1 infections.",623.67,"226700-81-8",100,160.34,"<1",0,"http://www.selleck.cn/products/fosamprenavir-calcium-salt.html","C25H34CaN3O9PS","Calcium salt","GW433908G","[Ca++].CC(C)CN(CC(O[P]([O-])([O-])=O)C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)[S](=O)(=O)C3=CC=C(N)C=C3",0.18,6,2,14]
["S6582","Ozenoxacin","e8","L1300-30","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA",null,208945,"Infection","Antibiotics","Microbiology","Ozenoxacin(T-3912) is a quinolone antibiotic used for the treatment of impetigo.",363.41,"245765-41-7",5,13.76,"<1",0,"http://www.selleck.cn/products/ozenoxacin.html","C21H21N3O3","Free Base","T-3912","CNC1=NC=C(C=C1C)C2=C(C)C3=C(C=C2)C(=O)C(=CN3C4CC4)C(O)=O",3.334,3,1,4]
["S6583","Apraclonidine HCl","f8","L1300-30","in 10mM DMSO","FDA,CFDA,DMF,NDC,PMDA,HMA","Martindale the Extra Pharmacopoei,USP42-NF37","077764","Ophthalmology","Adrenergic Receptor","Neuronal Signaling","Apraclonidine (Iopidine,ALO 2145) is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.",281.57,"73218-79-8",56,198.88,19,67.48,"http://www.selleck.cn/products/apraclonidine-hcl.html","C9H11Cl3N4","Hydrochloride","Iopidine HCl,ALO 2145","Cl.NC1=CC(=C(NC2=NCCN2)C(=C1)Cl)Cl",1.989,1,3,2]
["S6589","Norethisterone Enanthate","g8","L1300-30","in 10mM DMSO","CFDA,DMF",null,null,"Endocrinology","Others","Others","Norethisterone Enanthate (Norethindrone Enanthate) is a form of progestogen-only injectable birth control which is used to prevent pregnancy in women.",410.59,"3836-23-5",82,199.71,"<1",0,"http://www.selleck.cn/products/norethisterone-enanthate.html","C27H38O3","Free Base","Norethindrone Enanthate","CCCCCCC(=O)OC1(CCC2C3CCC4=CC(=O)CCC4C3CCC12C)C#C",7.186,3,0,7]
["S6593","Methylprednisolone sodium succinate","h8","L1300-30","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","Martindale the Extra Pharmacopoei, USP43-NF38, KP X",207667,"Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Methylprednisolone sodium succinate (U-9088, 6α-Methylprednisolone 21-hemisuccinate Sodium) is a corticosteroid medication that reduces inflammation.",496.53,"2375-03-3",99,199.38,99,199.38,"http://www.selleck.cn/products/methylprednisolone-sodium-succinate.html","C26H33NaO8","Sodium succinate","U-9088, 6α-Methylprednisolone 21-hemisuccinate Sodium","[Na+].CC1CC2C3CCC(O)(C(=O)COC(=O)CCC([O-])=O)C3(C)CC(O)C2C4(C)C=CC(=O)C=C14",0.262,4,1,7]
["S6624","Avatrombopag","a9","L1300-30","in 10mM DMSO","FDA,EMA,NDC",null,210238,"Hematology","TpoR","Immunology & Inflammation","Avatrombopag (AKR-501,E5501,YM477) is an orally administered, small-molecule thrombopoietin receptor (c-Mpl) agonist which increases platelet number, but not platelet activation.",649.65,"570406-98-3",20,30.79,"<1",0,"http://www.selleck.cn/products/avatrombopag.html","C29H34Cl2N6O3S2","Free Base","AKR-501,E5501,YM477","OC(=O)C1CCN(CC1)C2=C(Cl)C=C(C=N2)C(=O)NC3=NC(=C(S3)N4CCN(CC4)C5CCCCC5)C6=CC(=CS6)Cl",3.561,4,1,7]
["S6626","Brequinar (DUP785)","b9","L1300-30","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Infection","Dehydrogenase","Metabolism","Brequinar (DUP785, NSC 368390) is an inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of ∼20 nM in vitro.",375.37,"96187-53-0",37,98.57,"<1",0,"http://www.selleck.cn/products/brequinar.html","C23H15F2NO2","Free Base","NSC 368390","CC1=C(N=C2C=CC(=CC2=C1C(O)=O)F)C3=CC=C(C=C3)C4=C(F)C=CC=C4",6.008,2,0,3]
["S6631","Belotecan (CKD-602) hydrochloride","c9","L1300-30","in 10mM DMSO","marketed in Korea",null,null,"Others","Topoisomerase","DNA Damage/DNA Repair","Belotecan (CKD-602) is a potent DNA topoisomerase I inhibitor that exerts a clinical anticancer effect on various types of tumor.",469.96,"213819-48-8",47,100.01,4,8.51,"http://www.selleck.cn/products/belotecan-ckd-602-hydrochloride.html","C25H28ClN3O4","Hydrochloride","N/A","Cl.CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC=CC5=C4CCNC(C)C)C2=O",2.713,4,1,5]
["S6729","Besifovir","d9","L1300-30","in 10mM DMSO","marketed in Korea",null,null,"Infection","HBV","Microbiology","Besifovir is novel and potent acyclic nucleotide phosphonate used to treat hepatitis B virus (HBV) infection.",299.22,"441785-25-7",60,200.52,60,200.52,"http://www.selleck.cn/products/besifovir.html","C10H14N5O4P","Free Base","N/A","NC1=NC=C2N=C[N](CC3(CC3)OC[P](O)(O)=O)C2=N1",-0.821,4,1,5]
["S6742","Etofenamate","e9","L1300-30","in 10mM DMSO","CFDA,DMF,HMA","Martindale the Extra Pharmacopoei,EP8.8,BP2017",null,"Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Etofenamate is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.",369.34,"30544-47-9",0,"The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,"http://www.selleck.cn/products/etofenamate.html","C18H18F3NO4","Free Base","N/A","OCCOCCOC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)C=CC=C1",3.507,3,2,10]
["S7716","Pimitespib (TAS-116)","f9","L1300-30","in 10mM DMSO","PMDA",null,null,"Cancer","HSP (HSP90)","Cytoskeletal Signaling","Pimitespib (TAS-116) is a novel, small-molecule HSP90 inhibitor which inhibits geldanamycin-FITC binding to HSP90 proteins with Ki values of 34.7 nmol/L, 21.3 nmol/L, >50,000 nmol/L, and >50,000 nmol/L for HSP90α, HSP90β, GRP94, and TRAP1, respectively. Furthermore, TAS-116 does not inhibit other ATPases such as HSP70 (IC50 >200 μmol/L).",454.53,"1260533-36-5",91,200.21,"<1",0,"http://www.selleck.cn/products/tas-116.html","C25H26N8O","Free Base","N/A","CCC1=C(C=CC(=C1)C(N)=O)[N]2N=C(C(C)C)C3=C(C=CN=C23)[N]4C=NC(=C4)C5=C[N](C)N=C5",3.927,5,1,6]
["S8781","Selpercatinib (LOXO-292)","g9","L1300-30","in 10mM DMSO","FDA, NDC",null,213246,"Cancer","c-RET","Apoptosis","Selpercatinib (LOXO-292, ARRY-192) is a potent and specific RET (c-RET) inhibitor with IC50 values of 1 nM, 2 nM, 2 nM, 4 nM, 2 nM, 2 nM for WT RET, RET V804M, RET V804L, RET A883F, RET M918T and RET S891A respectively.",525.6,"2152628-33-4",25,47.56,"<1",0,"http://www.selleck.cn/products/loxo-292.html","C29H31N7O3","Free Base","ARRY-192","COC1=NC=C(CN2C3CC2CN(C3)C4=NC=C(C=C4)C5=CC(=C[N]6N=CC(=C56)C#N)OCC(C)(C)O)C=C1",2.884,5,0,8]
["S8848","Futibatinib (TAS-120)","h9","L1300-30","in 10mM DMSO","FDA, EMA, NDC, PMDA",null,214801,"Cancer","FGFR","Protein Tyrosine Kinase","Futibatinib (TAS-120) is an irreversible fibroblast growth factor receptor (FGFR) inhibitor which inhibits all 4 subtypes of FGFR with enzyme IC50 values of 1.8 nM, 1.4 nM, 1.6 nM and 3.7 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.",418.45,"1448169-71-8",84,200.74,"<1",0,"http://www.selleck.cn/products/tas-120.html","C22H22N6O3","Free Base","N/A","COC1=CC(=CC(=C1)C#CC2=N[N](C3CCN(C3)C(=O)C=C)C4=NC=NC(=C24)N)OC",2.402,6,1,6]
["S8861","Mavacamten (MYK-461)","a10","L1300-30","in 10mM DMSO","FDA, EMA, NDC, DMF",null,214998,"Cardiovascular Disease","MLCK","Cytoskeletal Signaling","Mavacamten (MYK-461, SAR439152) is a small-molecule modulator of cardiac myosin that targets the underlying sarcomere hypercontractility of hypertrophic cardiomyopathy (HCM), one of the most prevalent heritable cardiovascular disorders.",273.33,"1642288-47-8",55,201.22,"<1",0,"http://www.selleck.cn/products/myk-461.html","C15H19N3O2","Free Base","SAR439152","CC(C)N1C(=O)NC(=CC1=O)NC(C)C2=CC=CC=C2",2.093,2,2,4]
["S9015","Homoharringtonine (CGX-635)","b10","L1300-30","in 10mM DMSO","DMF,CFDA",null,null,"Cancer","STAT","JAK/STAT","Homoharringtonine (CGX-635, Omacetaxine mepesuccinate, HHT, Myelostat, NSC 141633), a plant alkaloid with antitumor properties, inhibits protein translation by preventing the initial elongation step of protein synthesis via an interaction with the ribosomal A-site. Homoharringtonine reversiblely inhibits IL-6-induced STAT3 Tyrosine 705 phosphorylation and reduced anti-apoptotic proteins expression.",545.62,"26833-87-4",10,18.33,0,0,"https://www.selleckchem.com/products/homoharringtonine.html","C29H39NO9",0,"Omacetaxine mepesuccinate, HHT, Myelostat, NSC 141633","COC(=O)CC(O)(CCCC(C)(C)O)C(=O)OC1C2C3=CC4=C(OCO4)C=C3CCN5CCCC25C=C1OC",2.418,7,0,11]
["S9019","Quillaic acid","c10","L1300-30","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Quillaic acid is the major aglycone of the widely studied saponins of the Chilean indigenous tree Quillaja saponaria Mol and shows strong anti-inflammatory activity.",486.68,"631-01-6",10,20.55,0,0,"https://www.selleckchem.com/products/quillaic-acid.html","C30H46O5","free base","FQ74391","CC1(C)CCC2(C(O)CC3(C)C(=CCC4C5(C)CCC(O)C(C)(C=O)C5CCC34C)C2C1)C(O)=O",4.51,2,2,2]
["S9024","3-O-Acetyl-11-keto-β-boswellic acid (AKBA)","d10","L1300-30","in 10mM DMSO","DMF",null,null,"Inflammation","Lipoxygenase","Metabolism","3-O-Acetyl-11-keto-β-boswellic acid (AKBA), the major active ingredient of the gum resin from Boswellia serrata and Boswellia carteri Birdw., exerts anti-inflammatory therapeutic effects and noncompetitively inhibits 5-lipoxygenase, topoisomerase, and leukocyte elastase.",512.72,"67416-61-9",100,195.04,0,0,"https://www.selleckchem.com/products/akba.html","C32H48O5",0,"FA42758","CC1CCC2(C)CCC3(C)C(=CC(=O)C4C5(C)CCC(OC(C)=O)C(C)(C5CCC34C)C(O)=O)C2C1C",6.081,4,0,3]
["S9028","Cimifugin","e10","L1300-30","in 10mM DMSO",null,"BP2019;EP9.2",null,"Immunology","Others","Immunology & Inflammation","Cimifugin is a bioactive component of Saposhnikovia divaricata, a Chinese herb for treating allergy.",306.31,"37921-38-3",10,32.65,0,0,"https://www.selleckchem.com/products/cimifugin.html","C16H18O6","free base","FC42575","COC1=C2CC(OC2=CC3=C1C(=O)C=C(CO)O3)C(C)(C)O",1.127,4,1,3]
["S9050","Boldine","f10","L1300-30","in 10mM DMSO",null,"USP42-NF37;BP2019;EP9.7;Martindale:The Extra Pharmacopoeia",null,"Immunology","Adrenergic Receptor","Neuronal Signaling","Boldine, isolated from Peumus boldus, has alpha-adrenergic antagonist activities in vascular tissue with anti-oxidant, hepatoprotective, cytoprotective, antipyretic and anti-inflammatory effects.",327.37,"476-70-0",10,30.55,0,0,"https://www.selleckchem.com/products/boldine.html","C19H21NO4","free base","1, 10-Dimethoxy-2, 9-dihydroxyaporphine; ex Peumus boldus","COC1=C(O)C=C2CC3N(C)CCC4=CC(=C(OC)C(=C34)C2=C1)O",3.083,2,2,2]
["S9053","Irisflorentin","g10","L1300-30","in 10mM DMSO",null,"BP2019;EP9.2;CP2005",null,"Others","Immunology & Inflammation related","Immunology & Inflammation","Irisflorentin derived from the roots of Belamcanda chinensis (L.) DC. is an herb which has been used for the treatment of inflammatory disorders in traditional Chinese medicine.",386.35,"41743-73-1",10,25.88,0,0,"https://www.selleckchem.com/products/irisflorentin.html","C20H18O8","free base","FI73921","COC1=CC(=CC(=C1OC)OC)C2=COC3=CC4=C(OCO4)C(=C3C2=O)OC",2.569,8,0,5]
["S9086","Dihydrocapsaicin","h10","L1300-30","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cancer/Gastroenterology/Infection","TRP Channel","Transmembrane Transporters","Dihydrocapsaicin (6,7-Dihydrocapsaicin, 8-Methyl-N-vanillylnonanamide, CCRIS1589), found in pepper (C. annuum), is a potential nutriceutical.DHC is a selective TRPV1 agonist.",307.43,"19408-84-5",10,32.53,0,0,"https://www.selleckchem.com/products/dihydrocapsaicin.html","C18H29NO3","free base","6,7-Dihydrocapsaicin, 8-Methyl-N-vanillylnonanamide, CCRIS1589","COC1=C(O)C=CC(=C1)CNC(=O)CCCCCCC(C)C",4.354,2,2,10]
["S9102","Magnolin","a11","L1300-30","in 10mM DMSO",null,"BP2019",null,"Inflammation","ERK","MAPK","Magnolin is a natural compound abundantly found in Magnolia flos targeting ERK1 (IC50=87 nM) and ERK2 (IC50=16.5 nM) and inhibits cell transformation induced by tumor promoters such as epidermal growth factor (EGF).",416.46,"31008-18-1",83,199.3,0,0,"https://www.selleckchem.com/products/magnolin.html","C23H28O7",0,0,"COC1=C(OC)C=C(C=C1)C2OCC3C2COC3C4=CC(=C(OC)C(=C4)OC)OC",2.618,7,0,7]
["S9110","Morin","b11","L1300-30","in 10mM DMSO",null,"USP42-NF37",null,"Others","Others","Others","Morin (Al-Morin, Aurantica, Calico Yellow, Toxylon pomiferum), a constituent of various woods, has a role as an antioxidant, a metabolite, an antihypertensive agent, a hepatoprotective agent, a neuroprotective agent, an anti-inflammatory agent, an antineoplastic agent, an antibacterial agent, a DNA topoisomerase inhibitor and an angiogenesis modulating agent.",302.24,"480-16-0",10,33.09,0,0,"https://www.selleckchem.com/products/morin.html","C15H10O7","free base","Al-Morin, Aurantica, Calico Yellow, Toxylon pomiferum","OC1=CC(=C(C=C1)C2=C(O)C(=O)C3=C(O2)C=C(O)C=C3O)O",1.63,2,5,1]
["S9111","Isorhamnetin","c11","L1300-30","in 10mM DMSO",null,"USP42-NF37",null,"Gastroenterology/Respiratory Disease","Tyrosinase","Proteases","Isorhamnetin (3-methylquercetin, 3'-Methoxyquercetin, Isorhamnetol), a natural flavonol aglycon, is a tyrosinase inhibitor and has antioxidant activity.",316.26,"480-19-3",63,199.2,0,0,"https://www.selleckchem.com/products/isorhamnetin.html","C16H12O7","free base","3-methylquercetin, 3'-Methoxyquercetin, Isorhamnetol","COC1=C(O)C=CC(=C1)C2=C(O)C(=O)C3=C(O2)C=C(O)C=C3O",1.856,3,4,2]
["S9123","Eriodictyol","d11","L1300-30","in 10mM DMSO","DMF",null,null,"Cardiovascular Disease/Metabolic Disease","Immunology & Inflammation related","Immunology & Inflammation","Eriodictyol, a flavonoid extracted from yerba santa, has anti-inflammatory and antioxidant activities and taste-modifying properties.",288.25,"552-58-9",57,197.74,0,0,"https://www.selleckchem.com/products/eriodictyol.html","C15H12O6","free base",0,"OC1=CC2=C(C(=O)CC(O2)C3=CC(=C(O)C=C3)O)C(=C1)O",2.131,2,4,1]
["S9171","Harpagoside","e11","L1300-30","in 10mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Others","Immunology & Inflammation related","Immunology & Inflammation","Harpagoside, a natural product found in the plant Harpagophytum procumbens, has potent anti-rheumatic, anti-inflammatory and analgesic effects.",494.49,"19210-12-9",99,200.21,0,0,"https://www.selleckchem.com/products/harpagoside.html","C24H30O11","free base",0,"CC1(CC(O)C2(O)C=COC(OC3OC(CO)C(O)C(O)C3O)C12)OC(=O)\\C=C\\C4=CC=CC=C4",-1.39,5,5,7]
["S9183","Ruscogenin","f11","L1300-30","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","Immunology & Inflammation related","Immunology & Inflammation","Ruscogenin, a major steroidal sapogenin of traditional Chinese herb Radix Ophiopogon japonicus, has been reported to exert significant anti-inflammatory and anti-thrombotic activities.",430.62,"472-11-7",86,199.71,0,0,"https://www.selleckchem.com/products/ruscogenin.html","C27H42O4","free base",0,"CC1CCC2(OC1)OC3CC4C5CC=C6CC(O)CC(O)C6(C)C5CCC4(C)C3C2C",3.408,2,2,0]
["S9192","Vitexin","g11","L1300-30","in 10mM DMSO",null,"BP2019;EP9.2",null,"Cancer/Inflammation","Others","Others","Vitexin (Apigenin-8-C-glucoside), an naturally occuring apigenin flavone glycoside, acts as a platelet aggregation and alpha-glucosidase inhibitor and shows antineoplastic activity.",432.38,"3681-93-4",47,108.7,0,0,"https://www.selleckchem.com/products/vitexin.html","C21H20O10","free base","Apigenin-8-C-glucoside","OCC1OC(C(O)C(O)C1O)C2=C(O)C=C(O)C3=C2OC(=CC3=O)C4=CC=C(O)C=C4",0.018,3,7,3]
["S9200","Pneumocandin B0","h11","L1300-30","in 10mM DMSO","DMF",null,null,"Others","Fungal","Microbiology","Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.",1065.21,"135575-42-7",100,93.88,0,0,"https://www.selleckchem.com/products/pneumocandin-b0.html","C50H80N8O17","free base","L-688786","CCC(C)CC(C)CCCCCCCCC(=O)NC1CC(O)C(O)NC(=O)C2C(O)CCN2C(=O)C(NC(=O)C(NC(=O)C3CC(O)CN3C(=O)C(NC1=O)C(C)O)C(O)C(O)C4=CC=C(O)C=C4)C(O)CC(N)=O",-2.334,8,15,20]
["S9224","Dehydroandrographolide Succinate","a2","L1300-31","in 10mM DMSO","CFDA",null,null,"Angiology/Infection/Inflammation","Antiviral,Bacterial","Microbiology","Dehydroandrographolide succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, has antibacterial and antiviral effects.",532.58,"786593-06-4",100,187.77,0,0,"https://www.selleckchem.com/products/dehydroandrographolide-succinate.html","C28H36O10","free base",0,"CC1(COC(=O)CCC(O)=O)C(CCC2(C)C1CCC(=C)C2\\C=C\\C3=CCOC3=O)OC(=O)CCC(O)=O",3.027,8,0,13]
["S9248","Homoorientin","b2","L1300-31","in 10mM DMSO",null,"BP2019;EP9.2",null,"Others","Immunology & Inflammation related","Immunology & Inflammation","Homoorientin (Isoorientin, Luteolin-6-C-glucoside) is a flavone that acts as a radical scavenger and an antineoplastic agent.",448.38,"4261-42-1",90,200.72,0,0,"https://www.selleckchem.com/products/homoorientin.html","C21H20O11",0,"Isoorientin, Luteolin-6-C-glucoside","OCC1OC(C(O)C(O)C1O)C2=C(O)C3=C(OC(=CC3=O)C4=CC(=C(O)C=C4)O)C=C2O",-0.224,3,8,3]
["S9270","Dracohodin perochlorate","c2","L1300-31","in 10mM DMSO",null,"CP2005",null,"Others","Others","Others","Dracohodin perochlorate, extracted from Dragon's blood, is widely used in traditional Chinese medicine, especially in wound healing.",366.75,"125536-25-6",73,199.05,0,0,"https://www.selleckchem.com/products/dracohodin-perochlorate.html","C17H15ClO7","free base",0,"COC1=C(C)C(=CC2=C1C=CC(=[O+]2)C3=CC=CC=C3)O.[O-][Cl](=O)(=O)=O",1.785,1,1,2]
["S9281","Peimine","d2","L1300-31","in 10mM DMSO",null,"CP2005",null,"Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Peimine (Verticine, Wanpeinine A) is a major biologically active component of Fritillaria ussuriensis, exhibits anti-inflammatory and pain suppression properties at the cellular level.",431.65,"23496-41-5",86,199.23,0,0,"https://www.selleckchem.com/products/peimine.html","C27H45NO3","free base","Verticine, Wanpeinine A","CC1CCC2N(C1)CC3C4CC5C(CC(O)C6CC(O)CCC56C)C4CCC3C2(C)O",3.396,0,2,0]
["S9285","Fargesin","e2","L1300-31","in 10mM DMSO",null,"BP2019",null,"Immunology","Adrenergic Receptor","Neuronal Signaling","Fargesin is a neolignan isolated from Magnolia plants. It is a potential β1AR antagonist through cAMP/PKA pathway.",370.4,"31008-19-2",36,97.19,0,0,"https://www.selleckchem.com/products/fargesin.html","C21H22O6","free base",0,"COC1=CC=C(C=C1OC)C2OCC3C2COC3C4=CC5=C(OCO5)C=C4",2.436,6,0,4]
["S9288","Casticin","f2","L1300-31","in 10mM DMSO",null,"BP2019;EP9.2",null,"Inflammation/Neurological Disease","Immunology & Inflammation related","Immunology & Inflammation","Casticin (Vitexicarpin), as the major active substance in Lithospermum erythrorhyzon, had been reported to mediate multiple pharmacological activities such as antioxidation, antiviral, cardiovascular protection, antineoplastic and anti-inflammation.",374.34,"479-91-4",75,200.35,0,0,"https://www.selleckchem.com/products/casticin.html","C19H18O8","free base","Vitexicarpin","COC1=C(O)C=C(C=C1)C2=C(OC)C(=O)C3=C(O2)C=C(OC)C(=C3O)OC",2.291,6,2,5]
["S9294","Gelsemine","g2","L1300-31","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","GlyR","Transmembrane Transporters","Gelsemine, a principal alkaloid from Gelsemium sempervirens Ait., is a highly toxic compound and may be a glycine receptor agonist with significantly higher binding affinity for some of these receptors than its native agonist, glycine.",322.4,"509-15-9",64,198.51,0,0,"https://www.selleckchem.com/products/gelsemine.html","C20H22N2O2","free base",0,"CN1CC2(C=C)C3CC4OCC3C1C2C45C(=O)NC6=CC=CC=C56",0.891,2,1,1]
["S9416","Triptonide","h2","L1300-31","in 10mM DMSO","CFDA",null,null,"Cancer","Wnt/beta-catenin","Stem Cells & Wnt","Triptonide, isolated from the roots of Tripterygium wilfordii, can effectively inhibit canonical Wnt/β-catenin signaling by targeting the downstream C-terminal transcription domain of β-catenin or a nuclear component associated with β-catenin. It is also an antineoplastic agent, an anti-inflammatory agent and an immunosuppressive agent.",358.39,"38647-11-9",71,198.11,0,0,"https://www.selleckchem.com/products/triptonide.html","C20H22O6","free base",0,"CC(C)C12OC1C3OC34C5(C)CCC6=C(COC6=O)C5CC7OC47C2=O",1.259,6,0,1]
["S9519","Fadrozole (CGS16949A)","a3","L1300-31","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Others","Aromatase","Endocrinology & Hormones","Fadrozole (CGS16949A) is a potent, selective, nonsteroidal inhibitor of aromatase with an IC50 of 4.5 nM and selectivity over other cytochrome P-450 enzymes.",223.27,"102676-47-1",45,201.55,"<1",0,"http://www.selleck.cn/products/fadrozole.html","C14H13N3","Free Base","CGS16949A","N#CC1=CC=C(C=C1)C2CCCC3=CN=C[N]23",2.271,1,0,1]
["S9520","Lasofoxifene Tartrate","b3","L1300-31","in 10mM DMSO","EMA","Martindale: The Complete Drug Reference","000977","Endocrinology/Cancer","Estrogen/progestogen Receptor","Endocrinology & Hormones","Lasofoxifene Tartrate is a third-generation, non-steroidal selective estrogen receptor modulator (SERM) which binds with high affinity to the human estrogen receptor-α with IC50 value of 1.5 nM.",563.64,"190791-29-8",100,177.42,"<1",0,"http://www.selleck.cn/products/lasofoxifene-tartrate.html","C32H37NO8","Free Base","N/A","OC(C(O)C(O)=O)C(O)=O.OC1=CC2=C(C=C1)C(C(CC2)C3=CC=CC=C3)C4=CC=C(OCCN5CCCC5)C=C4",1.554,3,3,9]
["S2100","Temocapril","c3","L1300-31","in 10mM DMSO","PMDA","JP17,Martindale the Extra Pharmacopoei",null,"Cardiovascular Disease","ACE,RAAS","Endocrinology & Hormones","Temocapril (CS-622,temocaprilum) is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.",476.61,"111902-57-9",95,199.32,"<1",0,"http://www.selleck.cn/products/temocapril.html","C23H28N2O5S2","Free Base","CS-622,temocaprilum","CCOC(=O)C(CCC1=CC=CC=C1)NC2CSC(CN(CC(O)=O)C2=O)C3=CC=CS3",0.405,4,1,11]
["S2307","Roquinimex","d3","L1300-31","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Angiology/Cancer","Immunology & Inflammation related","Immunology & Inflammation","Roquinimex (FCF 89, Linomide, LS 2616) is a novel immunomodulator augmenting natural killer (NK) cell activity and T-lymphocyte related effector functions. Roquinimex is a potent oral active tumor antiangiogenic agent. Roquinimex inhibits the secretion of TNF-α.",308.33,"84088-42-6",62,201.08,"<1",0,"http://www.selleck.cn/products/roquinimex.html","C18H16N2O3","Free Base","FCF 89, Linomide, LS 2616","CN(C1=CC=CC=C1)C(=O)C2=C(O)C3=C(C=CC=C3)N(C)C2=O",1.871,2,1,2]
["S2426","Tirapazamine","e3","L1300-31","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Cancer","Others","Others","Tirapazamine (NSC 130181, SR 259075, SR 4233, Tirazone, WIN 59075) is a new anticancer drug in solid tumours. Tirapazamine exhibits preferential tumour cell killing and high specific toxicity to cells at low oxygen tensions.",178.15,"27314-97-2",36,202.08,"<1",0,"http://www.selleck.cn/products/tirapazamine.html","C7H6N4O2","Free Base","NSC 130181, SR 259075, SR 4233, Tirazone, WIN 59075","NC1=[N+]([O-])C2=CC=CC=C2[N+](=N1)[O-]",-0.565,1,1,0]
["S2428","Isopropyl myristate","f3","L1300-31","in 10mM DMSO","DMF","Martindale the Extra Pharmacopoei,EP10.0,USP42-NF37,BP2017,IP2010",null,"Others","Others","Others","Isopropyl myristate (IPM) is used as a substitute for natural oils in cosmetics and a co-solvent with skin penetration enhancement properties of active ingredients in many topical and transdermal preparations. Isopropyl myristate is a novel pediculicide rinse (50%) and a safe and effective therapy for the treatment of head lice in children and adults.",270.45,"110-27-0",0,"The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,"http://www.selleck.cn/products/isopropyl-myristate.html","C17H34O2","Free Base","IPM","CCCCCCCCCCCCCC(=O)OC(C)C",6.432,2,0,14]
["S2474","Fabomotizole hydrochloride","g3","L1300-31","in 10mM DMSO","marketed in Russian",null,null,"Neurological Disease/Psychotic disorders","Others","Others","Fabomotizole hydrochloride (Fabomotizole, CM346, CM346, Afobazol, Afobazole) exhibits anxiolytic and neuroprotective properties. Fabomotizole hydrochloride is a potent sigma1-receptor agonist with IC50 of 7.1 µM and Ki of 5.9 µM.",343.87,"173352-39-1",69,200.66,69,200.66,"https://www.selleckchem.com/products/fabomotizole-hydrochloride.html","C15H22ClN3O2S","hydrochloride","Fabomotizole, CM346 hydrochloride, CM346, Afobazol, Afobazole, Afobazole hydrochloride","Cl.CCOC1=CC2=C([NH]C(=N2)SCCN3CCOCC3)C=C1",2.969,3,1,6]
["S2600","Fexinidazole","h3","L1300-31","in 10mM DMSO","FDA, NDA, NDC",null,214429,"Infection","DNA/RNA Synthesis","DNA Damage/DNA Repair","Fexinidazole (HOE-239, Fexinidazole Winthrop) is a 5-nitroimidazole derivative. Fexinidazole is a DNA synthesis inhibitor and the only, all-oral agent for Human African Trypanosomiasis(HAT or sleeping sickness).",279.31,"59729-37-2",56,200.49,"<1",0,"http://www.selleck.cn/products/fexinidazole.html","C12H13N3O3S","Free Base","HOE-239, Fexinidazole Winthrop","CSC1=CC=C(OCC2=NC=C([N]2C)[N+]([O-])=O)C=C1",2.244,2,0,5]
["S6657","2-Aminoethyl Diphenylborinate (2-APB)","a4","L1300-31","in 10mM DMSO",null,"USP42-NF37",null,"Others","Calcium Channel,TRP Channel","Transmembrane Transporters","2-Aminoethyl Diphenylborinate (2-APB) is an IP3 receptor inhibitor and regulate IP3-induced calcium release.2-APB also inhibits the SOC channel activity and activates TRP channel at higher concentrations.",225.09,"524-95-8",45,199.92,"<1",0,"http://www.selleck.cn/products/2-aminoethyl-diphenylborinate.html","C14H16BNO","Free Base","N/A","NCCOB(C1=CC=CC=C1)C2=CC=CC=C2",3.656,1,1,5]
["S6659","Rimegepant (BMS-927711)","b4","L1300-31","in 10mM DMSO","FDA, NDC",null,212728,"Neurological Disease","CGRP Receptor","GPCR & G Protein","Rimegepant (BMS-927711, BHV-3000) is a potent, selective, competitive human calcitonin gene-related peptide (CGRP) receptor antagonist with ki of 0.027 nM.",534.56,"1289023-67-1",100,187.07,"<1",0,"http://www.selleck.cn/products/bms-927711.html","C28H28F2N6O3","Free Base","BHV-3000","NC1C(CCC(OC(=O)N2CCC(CC2)N3C(=O)NC4=NC=CC=C34)C5=NC=CC=C15)C6=CC=CC(=C6F)F",2.898,5,2,4]
["S6663","Resmetirom (MGL-3196)","c4","L1300-31","in 10mM DMSO","FDA, NDC",null,217785,"Cardiovascular Disease; Endocrinology","THR","Metabolism","Resmetirom (MGL-3196, VIA-3196) is a liver-directed, orally active, selective thyroid hormone receptor β(THR-β) agonist with an EC50 of 0.21 μM,shows 28-fold selective for THR-β over THR-α in a functional assay.",435.22,"920509-32-6",87,199.9,"<1",0,"http://www.selleck.cn/products/mgl-3196.html","C17H12Cl2N6O4","Free Base","VIA-3196","CC(C)C1=CC(=NNC1=O)OC2=C(Cl)C=C(C=C2Cl)N3N=C(C#N)C(=O)NC3=O",3.021,6,2,4]
["S6665","Sparsentan (PS-433540, RE-021)","d4","L1300-31","in 10mM DMSO","EMA,FDA,NDC",null,"005783,216403 ","Cardiovascular Disease/Endocrinology","Angiotensin Receptor,Endothelin Receptor","GPCR & G Protein","Sparsentan (PS-433540, RE-021, DARA) is a dual endothelin type A receptor(ETA) and angiotensin II type 1 receptor antagonist.",592.75,"254740-64-2",100,168.71,"<1",0,"http://www.selleck.cn/products/sparsentan.html","C32H40N4O5S","Free Base","DARA","CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C(=C3)COCC)C4=CC=CC=C4[S](=O)(=O)NC5=NOC(=C5C)C",5.728,7,1,12]
["S6676","Ebselen","e4","L1300-31","in 10mM DMSO",null,"Martindale the Extra Pharmacopoei",null,"Others","COVID-19,HIV","Microbiology","Ebselen (DR 3305, SPI-1005, PZ-51, CCG-39161) is a small-molecule capsid inhibitor of HIV-1 Replication with IC50 of 46.1 nM in TR-FRET assay.",274.18,"60940-34-3",55,200.6,"<1",0,"http://www.selleck.cn/products/ebselen.html","C13H9NOSe","Free Base","DR 3305, SPI-1005, PZ-51, CCG-39161","O=C1N([Se]C2=C1C=CC=C2)C3=CC=CC=C3",3.227,1,0,1]
["S8949","Olutasidenib (FT-2102)","f4","L1300-31","in 10mM DMSO","FDA,NDC",null,"215814","Cancer/Inflammation/Immunology","Dehydrogenase","Metabolism","Olutasidenib is a potent, orally bioavailable, brain penetrant and selective mutant IDH1 (mIDH1) inhibitor with IC50 of 21.1 nM, 114 nM for IDH1-R132H, IDH1-R132C, respectively.",354.79,"1887014-12-1",71,200.12,"<1",0,"http://www.selleck.cn/products/olutasidenib-ft-2102.html","C18H15ClN4O2","Free Base","N/A","CC(NC1=CC=C(C#N)N(C)C1=O)C2=CC3=C(NC2=O)C=CC(=C3)Cl",1.234,2,2,3]
["S5617","Myristic Acid","g4","L1300-31","in 10mM DMSO","NDC","USP42-NF37,EP9.1,BP2017",null,"Others","Src","Angiogenesis","Myristic acid (Tetradecanoic acid) is a fatty acid that occurs naturally in some foods. Myristic acid inhibits the phosphorylation of poly E4Y by Src with an Ki of 35 μM.",228.37,"544-63-8",0,10,0,0,"https://www.selleckchem.com/products/myristic-acid.html","C14H28O2","free base","Tetradecanoic acid","CCCCCCCCCCCCCC(O)=O",5.48,1,0,12]
["S0436","Pleconaril","h4","L1300-31","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Infection","Enterovirus","Microbiology","Pleconaril (APO-P001, Picovir, VP 63843, WIN 63843) is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication with IC50 of < 0.050 μM.",381.35,"153168-05-9",76,199.29,"˂1",0,"http://www.selleckchem.com/products/pleconaril.html","C18H18F3N3O3","Free Base","APO-P001, Picovir, VP 63843, WIN 63843","CC1=NOC(=C1)CCCOC2=C(C)C=C(C=C2C)C3=NOC(=N3)C(F)(F)F",4.492,6,0,7]
["S0487","Sulfatinib","a5","L1300-31","in 10mM DMSO","CFDA",null,null,"Cancer","CSF-1R,FGFR,VEGFR","Protein Tyrosine Kinase","Sulfatinib (HMPL-012, Sufatinib, Surfatinib, Surufatinib) is a potent and highly selective tyrosine kinase inhibitor against VEGFR1, VEGFR2, VEGFR3, FGFR1 and CSF1R with IC50 of 2 nM, 24 nM, 1 nM, 15 nM and 4 nM, respectively. Sulfatinib shows encouraging antitumor activity and manageable toxicities in patients with advanced NETs.",480.58,"1308672-74-3",96,199.76,"˂1",0,"http://www.selleckchem.com/products/sulfatinib.html","C24H28N6O3S","Free Base","HMPL-012, Sufatinib, Surfatinib, Surufatinib","CN(C)CCN[S](=O)(=O)CC1=CC(=CC=C1)NC2=NC=CC(=N2)OC3=CC4=C([NH]C(=C4)C)C=C3",3.717,5,3,10]
["S2288","Rubitecan","b5","L1300-31","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cancer","Topoisomerase","DNA Damage/DNA Repair","Rubitecan (9-NC, 9-Nitro-camptothecin, Partaject Orathecin, Partaject rubitecan, RFS 2000) is a topoisomerase I inhibitor extracted from the bark and leaves of the Camptotheca acuminata tree, which is native to China. Rubitecan is an oral camptothecin with antitumour activity.",393.35,"91421-42-0",58,147.45,"<1",0,"http://www.selleckchem.com/products/rubitecan.html","C20H15N3O6","Free Base","9-NC, 9-Nitro-camptothecin, Partaject Orathecin, Partaject rubitecan, RFS 2000","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC=C(C5=C4)[N+]([O-])=O)C2=O",1.64,4,0,2]
["S2447","Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222)","c5","L1300-31","in 10mM DMSO","DMF",null,null,"Cancer","ADC Cytotoxin,Microtubule Associated","Cytoskeletal Signaling","Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222, Antibiotic C 15003P3) is a potent inhibitor of tubulin polymerization with IC50 of 3.4 μM.",635.14,"66584-72-3",100,157.45,"<1",0,"http://www.selleckchem.com/products/ansamitocin-p-3-maytansinol-isobutyrate.html","C32H43ClN2O9","Free Base","Antibiotic C 15003P3","COC1\\C=C\\C=C(C)\\CC2=CC(=C(Cl)C(=C2)OC)N(C)C(=O)CC(OC(=O)C(C)C)C3(C)OC3C(C)C4CC1(O)NC(=O)O4",4.445,8,1,5]
["S6813","Mobocertinib (TAK788)","d5","L1300-31","in 10mM DMSO","FDA",null,null,"Cancer","EGFR,HER2","Protein Tyrosine Kinase","Mobocertinib (TAK788, AP32788), an investigational TKI, is a potent, selective preclinical inhibitor of epidermal growth factor receptor (EGFR) and HER2 mutations. Mobocertinib (TAK788) is an antineoplastic agent.",585.7,"1847461-43-1",9,15.37,"<1",0,"http://www.selleckchem.com/products/tak788.html","C32H39N7O4","Free Base","AP32788","COC1=C(NC2=NC=C(C(=O)OC(C)C)C(=N2)C3=C[N](C)C4=CC=CC=C34)C=C(NC(=O)C=C)C(=C1)N(C)CCN(C)C",5.252,6,2,13]
["S6829","Dithiothreitol (DTT)","e5","L1300-31","in 10mM DMSO","DMF","BP2017,USP43-NF38,EP9.2",null,"Others","Others","Others","Dithiothreitol (DTT, Cleland's reagent), a small-molecule redox reagent, is a standard agent for reducing disulfide bonds between and within biological molecules.",154.25,"3483-12-3",31,200.97,31,200.97,"http://www.selleckchem.com/products/dtt.html","C4H10O2S2","Free Base","Cleland's reagent","OC(CS)C(O)CS",0.023,0,2,3]
["S6830","o-Phenanthroline","f5","L1300-31","in 10mM DMSO",null,"USP43-NF38",null,"Others","MMP","Proteases","o-Phenanthroline (1,10-Phenanthroline, phen), a hypoxia-mimicking agent, is a non-specific matrix metalloproteinase (MMP) inhibitor with IC50 of 110.5μM for Collagenase. O-phenanthroline reduces the expression of MMP3 and MMP13 mRNA levels during chondrogenic differentiation of human chondrocytes (hChs), as well as after TNFα/IL-1β exposure in an explant model. o-Phenanthroline is also a metal chelator which prevents the induction of chromosomal aberrations in streptozotocin-treated cells and forms a red chelate with Fe2+ that absorbs maximally at 510 nm.",180.21,"66-71-7",36,199.77,"<1",0,"http://www.selleckchem.com/products/o-phenanthroline.html","C12H8N2","Free Base","1,10-Phenanthroline, phen","C1=CN=C2C(=C1)C=CC3=CC=CN=C23",2.202,2,0,0]
["S6848","3'-Fluoro-3'-deoxythymidine (Alovudine)","g5","L1300-31","in 10mM DMSO",null,"EP10.0, BP2020",null,"Others","DNA/RNA Synthesis,HIV,Reverse Transcriptase","Microbiology","3'-Fluoro-3'-deoxythymidine (Alovudine, CL 184824, FddThd, FLT, MIV-310) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the  chemotherapy of pancreatic cancer.",244.22,"25526-93-6",49,200.64,20,81.89,"http://www.selleckchem.com/products/3-fluoro-3-deoxythymidine.html","C10H13FN2O4","Free Base","CL 184824, FddThd, FLT, MIV-310","CC1=CN(C2CC(F)C(CO)O2)C(=O)NC1=O",-0.298,3,2,2]
["S8969","Molnupiravir (EIDD-2801)","h5","L1300-31","in 10mM DMSO","NDC, PMDA, DMF",null,null,"Infection","COVID-19,SARS-CoV","Microbiology","Molnupiravir (EIDD-2801, MK-4482) is an orally bioavailable prodrug of the ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931) with broad-spectrum antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV, and the causative agent of COVID-19.",329.31,"2349386-89-4",66,200.42,20,60.73,"http://www.selleckchem.com/products/eidd-2801.html","C13H19N3O7","Free Base","MK-4482","CC(C)C(=O)OCC1OC(C(O)C1O)N2C=C\\C(NC2=O)=N/O",-0.875,5,3,5]
["S0074","Relebactam","a6","L1300-31","in 10mM DMSO","FDA, EMA, NDC",null,212819,"Infection","β-lactamase","Immunology & Inflammation","Relebactam (MK-7655) is a potent inhibitor against KPC-2, class A and class C (AmpC) β-lactamases.",348.38,"1174018-99-5",70,200.93,70,200.93,"http://www.selleckchem.com/products/relebactam.html","C12H20N4O6S","free base","MK-7655","O[S](=O)(=O)ON1C2CCC(N(C2)C1=O)C(=O)NC3CCNCC3",-1.759,3,2,4]
["S0088","Pemigatinib (INCB054828)","b6","L1300-31","in 10mM DMSO","FDA, NDC",null,213736,"Cancer","FGFR","Angiogenesis","Pemigatinib (INCB054828, Pemazyre) is an orally active and selective inhibitor of FGFR with IC50 of 0.4 nM, 0.5 nM, 1.2 nM and 30 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. Pemigatinib has the potential for cholangiocarcinoma.",487.5,"1513857-77-6",40,82.05,"<1",0,"http://www.selleckchem.com/products/pemigatinib-incb054828.html","C24H27F2N5O4","free base","Pemazyre","CCN1C(=O)N(CC2=C1C3=C([NH]C(=C3)CN4CCOCC4)N=C2)C5=C(F)C(=CC(=C5F)OC)OC",2.596,5,1,6]
["S0325","Treprostinil sodium","c6","L1300-31","in 10mM DMSO","DMF, EMA, HMA","Martindale:The Extra Pharmacopoeia",null,"Hematology","Prostaglandin Receptor","GPCR & G Protein","Treprostinil sodium (UT-15, Remodulin, Orenitram, Tyvaso, Trevyent) is a potent agonist of DP1, EP2 and IP receptors with Ki 4.4 nM, 3.6 nM and 32 nM, respectively.",412.49,"289480-64-4",82,198.79,82,198.79,"http://www.selleckchem.com/products/treprostinil-sodium.html","C23H33NaO5","sodium","UT-15, Remodulin, Orenitram, Tyvaso, Trevyent","CCCCCC(O)CCC1C(O)CC2CC3=C(OCC(=O)O[Na])C=CC=C3CC12",4.526,3,2,11]
["S0398","Astemizole","d6","L1300-31","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia, EP10.2, USP43-NF38",null,"Immunology","Histamine Receptor,Potassium Channel","Neuronal Signaling","Astemizole (R 43512) is a histamine H1-receptor antagonist with IC50 of 4.7 nM. Astemizole is also a potent inhibitor of ether à-go-go 1 (Eag1) and Eag-related gene (Erg) potassium channels. Astemizole has antineoplastic and antipruritic effects.",458.57,"68844-77-9",92,200.62,"<1",0,"http://www.selleckchem.com/products/astemizole.html","C28H31FN4O","free base","R 43512","COC1=CC=C(CCN2CCC(CC2)NC3=NC4=CC=CC=C4[N]3CC5=CC=C(F)C=C5)C=C1",5.689,2,1,8]
["S0994","Ipragliflozin L-Proline","e6","L1300-31","in 10mM DMSO","DMF",null,null,"Others","SGLT","GPCR & G Protein","Ipragliflozin L-Proline is an orally active and selective inhibitor of SGLT2 with IC50 of 7.38 nM, 6.73 nM and 5.64 nM for human SGLT2, rat SGLT2 and mouse SGLT2, respectively.",519.58,"951382-34-6",35,67.36,"<1",0,"http://www.selleckchem.com/products/ipragliflozin-l-proline.html","C26H30FNO7S","free base","N/A","OCC1OC(C(O)C(O)C1O)C2=CC(=C(F)C=C2)CC3=CC4=CC=CC=C4S3.OC(=O)C5CCCN5",-0.493,2,5,5]
["S2440","Vindesine sulfate","f6","L1300-31","in 10mM DMSO","CFDA, PMDA","Martindale:The Extra Pharmacopoeia, EP10.2",null,"Cancer","Microtubule Associated","Cytoskeletal Signaling","Vindesine sulfate (Eldesine, Eldisine, Desacetyl Vinblastine amide, Desacetylvinblastine amide, DAVA, DVA, VDS), a vinca alkaloid derived from Catharanthus roseus, is a potent inhibitor of mitosis with antineoplastic activities. Vindesine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death.",852,"59917-39-4",100,117.37,100,117.37,"http://www.selleckchem.com/products/vindesine-sulfate.html","C43H57N5O11S","sulfate","Eldesine, Eldisine, Desacetyl Vinblastine amide, Desacetylvinblastine amide, DAVA, DVA, VDS","CCC1(O)CC2CN(CCC3=C([NH]C4=CC=CC=C34)C(C2)(C(=O)OC)C5=C(OC)C=C6N(C)C7C(O)(C(O)C8(CC)C=CCN9CCC7(C89)C6=C5)C(N)=O)C1.O[S](O)(=O)=O",3.047,4,3,7]
["S3217","Brilliant Blue G","g6","L1300-31","in 10mM DMSO","FDA, NDC","USP43-NF38",209569,"Diagnosis","Dyes,P2 Receptor","Neuronal Signaling","Brilliant Blue G (BBG) is a potent non-competitive antagonist of P2X7 receptor with IC50 of 10.1 nM and 265 nM for rat P2X7 and human P2X7, respectively. Brilliant Blue G is a dye which is commonly used in laboratories to stain or quantify proteins.",854.02,"6104-58-1",100,117.09,100,117.09,"http://www.selleckchem.com/products/brilliant-blue-g.html","C47H48N3NaO7S2","free base","BBG","[Na+].CCOC1=CC=C(NC2=CC=C(C=C2)\\C(C3=CC=C(C=C3C)N(CC)CC4=CC=CC(=C4)[S]([O-])(=O)=O)=C/5C=CC(/C=C5C)=[N+](/CC)CC6=CC=CC(=C6)[S]([O-])(=O)=O)C=C1",5.617,1,1,15]
["S3220","Trigonelline","h6","L1300-31","in 10mM DMSO",null,"EP10.2",null,"Endocrinology/Metabolic Disease","Akt,Anti-infection,Microtubule Associated,Phospholipase (e.g. PLA),PI3K","Metabolism","Trigonelline (Trigenolline) is a plant alkaloid and a major component of coffee and fenugreek with anti-degranulation, anti-diabetic, antioxidant, anti-inflammatory, and neuroprotective effects. Trigonelline inhibits FcεRI-mediated intracellular signaling pathways, such as phosphorylation of PLCγ1, PI3K, and Akt. Trigonelline (Trigenolline) also inhibits the microtubule formation in RBL-2H3 cells.",137.14,"535-83-1",50,364.59,-1,0,"http://www.selleckchem.com/products/trigonelline.html","C7H7NO2","free base","Trigenolline","C[N+]1=CC(=CC=C1)C([O-])=O",-0.41,0,0,1]
["S3273","Hypericin","a7","L1300-31","in 10mM DMSO",null,"Martindale:The Extra Pharmacopoeia, EP10.2",null,"Cancer/Infection","Hydroxylase,MAO,P450 (e.g. CYP17),PKC,Reverse Transcriptase,Telomerase","Metabolism","Hypericin (Hyp, HY) is a naturally occurring substance found in the common St. John's Wort (Hypericum species) with antidepressive, antineoplastic and antiviral (human immunodeficiency and hepatitis C virus) activities. Hypericin has inhibitory effects on MAO (monoaminoxidase), PKC (protein kinase C), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450).",504.44,"548-04-9",100,198.24,-1,0,"http://www.selleckchem.com/products/hypericin.html","C30H16O8","free base","Hyp, HY","CC1=C2C3=C(C)C=C(O)C4=C3C5=C6C2=C(C(=C1)O)C(=O)C7=C6C(=C(O)C=C7O)C8=C(O)C=C(O)C(=C58)C4=O",5.04,2,6,0]
["S3301","Cynarin","b7","L1300-31","in 10mM DMSO",null,"EP10.2",null,"Immunology/Infection","CD markers,Glutathione,Nrf2,ROS","Immunology & Inflammation","Cynarin (Cynarine) is an artichoke phytochemical that possesses a variety of pharmacological features including free-radical scavenging, antioxidant, antihistamic and antiviral activities. Cynarin blocks the interaction between the CD28 of T-cell receptor and CD80 of antigen presenting cells. Cynarin triggers Nrf2 nuclear translocation, restores the balance of glutathione (GSH) and reactive oxygen species (ROS), and inhibits mitochondrial depolarization.",516.45,"30964-13-7",100,193.63,-1,0,"http://www.selleckchem.com/products/cynarin.html","C25H24O12","free base","Cynarine","OC1CC(CC(OC(=O)/C=C/C2=CC=C(O)C(=C2)O)C1O)(OC(=O)\\C=C\\C3=CC=C(O)C(=C3)O)C(O)=O",1.687,5,6,9]
["S6664","Gefapixant","c7","L1300-31","in 10mM DMSO","EMA,PMDA,CFDA",null,"005476,005884","Inflammation/Immunology","P2 Receptor","Neuronal Signaling","Gefapixant (AF-219, MK-7264, R1646, RG-1646, RO 4926219) is an orally active small molecule antagonist of human P2X3 receptor with IC50 of about 30 nM, 100–250 nM for recombinant hP2X3 homotrimers and hP2X2/3 heterotrimeric receptors, respectively. Gefapixant has shown promise for the treatment of refractory and unexplained chronic cough.",353.4,"1015787-98-0",71,200.91,"<1",0,"http://www.selleckchem.com/products/gefapixant.html","C14H19N5O4S","free base","AF-219, MK-7264, R1646,RG-1646,RO 4926219","COC1=CC(=C(OC2=CN=C(N)N=C2N)C=C1[S](N)(=O)=O)C(C)C",1.061,6,3,5]
["S6852","Gossypol","d7","L1300-31","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Others","Apoptosis related,Bcl-2,Dehydrogenase","Apoptosis","Gossypol (BL 193) is an orally-active polyphenol isolated from cotton seeds and roots. Gossypol is a potent inhibitor of 5α-reductase 1 and 3α-hydroxysteroid dehydrogenase with IC50 of 3.33 μM and 0.52 μM in cell-free assay, respectively. Gossypol also inhibits the binding of BH3 peptide to Bcl protein with IC50 of 0.4 μM and 10 μM for Bcl-XL and Bcl-2, respectively. Gossypol induces apoptosis and cell growth inhibition in various cancer cells.",518.55,"303-45-7",100,192.85,"<1",0,"http://www.selleckchem.com/products/gossypol.html","C30H30O8","free base","BL 193","CC(C)C1=C(O)C(=C(C=O)C2=C1C=C(C)C(=C2O)C3=C(O)C4=C(C=C3C)C(=C(O)C(=C4C=O)O)C(C)C)O",6.592,2,6,5]
["S6889","Monomethyl Fumarate","e7","L1300-31","in 10mM DMSO","FDA, DMF, NDC",null,210296,"Neurological Disease/Ophthalmology","Apoptosis related,Autophagy,GPR","GPCR & G Protein","Monomethyl Fumarate (MMF, Monomethylfumarate, Fumaric acid monomethyl ester, Methyl hydrogen fumarate), the active metabolite of the psoriasis drug Fumaderm, is a potent GPR109A agonist. Monomethyl Fumarate prevents major dysfunctions associated with neurodegenerative diseases: oxidative stress, mitochondrial dysfunction, apoptosis and autophagy.",130.1,"2756-87-8",26,199.85,20,153.73,"http://www.selleckchem.com/products/monomethyl-fumarate.html","C5H6O4","free base","MMF, Monomethylfumarate, Fumaric acid monomethyl ester, Methyl hydrogen fumarate","COC(=O)\\C=C\\C(O)=O",0.264,3,0,3]
["S6896","Clascoterone","f7","L1300-31","in 10mM DMSO","FDA",null,213433,"Inflammation/Cardiovascular Disease","Androgen Receptor","Endocrinology & Hormones","Clascoterone (Winlevi, Cortexolone 17 alpha-propionate, Cortexolone 17α-propionate, CB-03-01) is a topical and peripherally selective antagonist of androgen receptor (AR).",402.52,"19608-29-8",80,198.75,"<1",0,"http://www.selleckchem.com/products/clascoterone.html","C24H34O5","free base","Winlevi, Cortexolone 17 alpha-propionate, Cortexolone 17α-propionate, CB-03-01","CCC(=O)OC1(CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C)C(=O)CO",3.498,4,1,5]
["S6906","Capric acid","g7","L1300-31","in 10mM DMSO",null,"EP10.2, USP42-NF37",null,"Others","GluR,PPAR","Neuronal Signaling","Capric acid (DA, Decanoic acid, Decylic acid), a component of medium-chain triclycerides occurring naturally in coconut oil and palm kernel oil, contributes to seizure control through direct AMPA receptor inhibition. Capric acid is also a modulating ligand for PPARs. Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.",172.26,"334-48-5",34,197.38,34,197.38,"http://www.selleckchem.com/products/capric-acid.html","C10H20O2","free base","DA, Decanoic acid, Decylic acid","CCCCCCCCCC(O)=O",3.655,1,0,8]
["S9600","Orelabrutinib (ICP-022)","h7","L1300-31","in 10mM DMSO","CFDA",null,null,"Cancer","BTK","Angiogenesis","Orelabrutinib (ICP-022) is a potent, orally active and irreversible inhibitor of Bruton's tyrosine kinase (BTK). Orelabrutinib has potential antineoplastic activity.",427.49,"1655504-04-3",86,201.17,"<1",0,"http://www.selleckchem.com/products/orelabrutinib.html","C26H25N3O3","free base","ICP-022","NC(=O)C1=C(N=C(C=C1)C2CCN(CC2)C(=O)C=C)C3=CC=C(OC4=CC=CC=C4)C=C3",4.055,4,1,6]
["S9641","Pibrentasvir (ABT-530)","a8","L1300-31","in 10mM DMSO","FDA, EMA, NDC",null,209394,"Infection","HCV Protease","Proteases","Pibrentasvir (ABT-530) is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with EC50 ranging from 1.4 pM to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6.",1113.18,"1353900-92-1",100,89.83,"<1",0,"http://www.selleckchem.com/products/pibrentasvir-abt-530-.html","C57H65F5N10O8","free base","N/A","COC(C)C(NC(=O)OC)C(=O)N1CCCC1C2=NC3=C([NH]2)C=C(C4CCC(N4C5=CC(=C(N6CCC(CC6)C7=CC=C(F)C=C7)C(=C5)F)F)C8=CC9=C(C=C8F)N=C([NH]9)C%10CCCN%10C(=O)C(NC(=O)OC)C(C)OC)C(=C3)F",8.515,10,4,17]
["S0165","Ampalex (CX-516)","b8","L1300-31","in 10mM DMSO","DMF",null,null,"Neurological Disease/Psychotic disorders","GluR","Neuronal Signaling","Ampalex (CX-516, Ampakine CX 516, BDP-12, SPD 420) is a positive allosteric modulator of AMPA receptor. Ampalex exhibits potential treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI).",241.29,"154235-83-3",48,198.93,48,198.93,"https://www.selleckchem.com/products/cx-516.html","C14H15N3O","Free Base","Ampakine CX 516, BDP-12, SPD 420","O=C(N1CCCCC1)C2=CC3=NC=CN=C3C=C2",1.625,3,0,1]
["S0323","Antineoplaston A10","c8","L1300-31","in 10mM DMSO","DMF",null,null,"Cancer","Ras","Apoptosis","Antineoplaston A10 is a naturally occurring substance in the human body that that can be potentially used for the treatment of glioma, lymphoma, astrocytoma and breast cancer. The main ingredient active of antineoplaston A10 (Phenylacetylglutamine, PG) inhibits RAS and promotes apoptosis.",246.26,"91531-30-5",49,198.98,"<1",0,"https://www.selleckchem.com/products/antineoplaston-a10.html","C13H14N2O3","Free Base","N/A","O=C1CCC(NC(=O)CC2=CC=CC=C2)C(=O)N1",0.307,3,2,3]
["S0474","Avacopan (CCX168)","d8","L1300-31","in 10mM DMSO","FDA,EMA,NDC,PMDA,CFDA",null,"005523,004487,214487","Inflammation/Immunology","CD markers","Immunology & Inflammation","Avacopan (CCX168) is an orally administered and selective C5a receptor (C5aR) antagonist.",581.64,"1346623-17-3",100,171.93,"<1",0,"https://www.selleckchem.com/products/avacopan-ccx168-.html","C33H35F4N3O2","Free Base","CCX168","CC1=C(C=C(NC(=O)C2CCCN(C2C3=CC=C(NC4CCCC4)C=C3)C(=O)C5=C(C)C=CC=C5F)C=C1)C(F)(F)F",7.579,2,2,7]
["S0721","Ticlopidine","e8","L1300-31","in 10mM DMSO","FDA, DMF, CFDA, PMDA","EP10.4, USP43-NF38, KP Ⅹ, JP17","075089","Angiology/Cardiovascular Disease","Adenosine Receptor,P450 (e.g. CYP17)","Metabolism","Ticlopidine (Yuclid, Ticlopidinum, Ticlopidina,PCR 5332) is an orally active inhibitor of platelet aggregation induced by adenosine diphosphate (ADP). Ticlopidine is also an inhibitor of CYP2B6 with Ki of 0.2 μM.",263.79,"55142-85-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"https://www.selleckchem.com/products/ticlopidine.html","C14H14ClNS","Free Base","Yuclid, Ticlopidinum, Ticlopidina,PCR 5332","ClC1=CC=CC=C1CN2CCC3=C(C2)C=CS3",3.893,0,0,2]
["S0869","Carbetapentane","f8","L1300-31","in 10mM DMSO","DMF, CFDA, PMDA","KP Ⅹ, JP17",null,"Inflammation/Respiratory Disease","Sigma Receptor","GPCR & G Protein","Carbetapentane (Pentoxyverine, CB) is an antitussive anticonvulsant nonselective sigma-1 (σ1) agonist.",333.46,"77-23-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"https://www.selleckchem.com/products/carbetapentane.html","C20H31NO3","Free Base","Pentoxyverine, CB","CCN(CC)CCOCCOC(=O)C1(CCCC1)C2=CC=CC=C2",3.845,3,0,11]
["S0870","Barnidipine","g8","L1300-31","in 10mM DMSO","PMDA",null,null,"Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Barnidipine (Libradin, Mepirodipine, Vasexten, YM-09730-5, Cyress, Hypoca, Oldeca) is an antihypertensive drug that belongs to the dihydropyridine (DHP) group of calcium antagonist (CaA) with Ki of 0.21 nM for [3H]nitrendipine binding sites.",491.54,"104713-75-9",98,199.37,"<1",0,"https://www.selleckchem.com/products/barnidipine.html","C27H29N3O6","Free Base","Libradin, Mepirodipine, Vasexten, YM-09730-5, Cyress, Hypoca, Oldeca","COC(=O)C1=C(C)NC(=C(C1C2=CC(=CC=C2)[N+]([O-])=O)C(=O)OC3CCN(C3)CC4=CC=CC=C4)C",3.398,4,1,9]
["S1198","Irinotecan (CPT-11)","h8","L1300-31","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","EP10.4, USP43-NF38, IP2010","077219","Cancer","Topoisomerase","DNA Damage/DNA Repair","Irinotecan (CPT-11, (+)-Irinotecan) is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively.",586.68,"97682-44-5",51,86.93,"<1",0,"https://www.selleckchem.com/products/Irinotecan-cpt-11.html","C33H38N4O6","Free Base","(+)-Irinotecan,CPT-11","CCC1=C2C=C(OC(=O)N3CCC(CC3)N4CCCCC4)C=CC2=NC5=C1CN6C(=O)C7=C(C=C56)C(O)(CC)C(=O)OC7",3.686,6,0,5]
["S1421","Staurosporine (AM-2282)","a9","L1300-31","in 10mM DMSO","DMF",null,null,"Cancer/Infection","ADC Cytotoxin,Antineoplastic and Immunosuppressive Antibiotics,CaMK,PKA,PKC,PKG,S6 Kinase","TGF-beta/Smad","Staurosporine (AM-2282, Antibiotic AM-2282, STS) is a potent PKC inhibitor for PKCα, PKCγ and PKCη with IC50 of 2 nM, 5 nM and 4 nM, less potent to PKCδ (20 nM), PKCε (73 nM) and little active to PKCζ (1086 nM) in cell-free assays. Also shows inhibitory activities on other kinases, such as PKA, PKG, S6K, CaMKII, etc. Phase 3.",466.53,"62996-74-1",93,199.34,"<1",0,"https://www.selleckchem.com/products/Staurosporine.html","C28H26N4O3","Free Base","Antibiotic AM-2282, STS","CNC1CC2OC(C)(C1OC)[N]3C4=C(C=CC=C4)C5=C6CNC(=O)C6=C7C8=CC=CC=C8[N]2C7=C35",3.819,3,2,2]
["S1981","Adenine","b9","L1300-31","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.4, USP43-NF38, KP Ⅹ, IP2010","076404","Nutritional support","DNA/RNA Synthesis","DNA Damage/DNA Repair","Adenine(6-Aminopurine) is a purine derivative and a nucleobase with a variety of roles in biochemistry.",135.13,"73-24-5",10,74,"<1",0,"https://www.selleckchem.com/products/adenine.html","C5H5N5","Free Base","6-Aminopurine","NC1=NC=NC2=C1N=C[NH]2",-0.442,3,2,0]
["S2997","DL-Tartaric acid","c9","L1300-31","in 10mM DMSO","DMF,CFDA,FDA,PMDA","USP40-NF35,IP2010,JP16","018509","Others","Others","Others","DL-Tartaric Acid (2,3-Dihydroxysuccinic acid) is a white, crystalline organic acid isolated from many plants, particularly tamarinds and grapes and is used as an antioxidant and an additive agent to give a sour taste.",150.09,"133-37-9, 526-83-0",30,199.88,30,199.88,"https://www.selleckchem.com/products/dl-tartaric-acid.html","C4H6O6","Free Base","2,3-Dihydroxysuccinic acid","OC(C(O)C(O)=O)C(O)=O",-1.664,2,2,3]
["S3009","Menthone","d9","L1300-31","in 10mM DMSO",null,"EP10.4",null,"Others","DNA/RNA Synthesis","DNA Damage/DNA Repair","Menthone is one of the main volatile components of the essential oil of peppermint (Mentha piperita L.). Menthone is used as antioxidant agent and has a good compensatory effect with significant reduction in DNA damages in sperm cells.",154.25,"10458-14-7","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"https://www.selleckchem.com/products/menthone.html","C10H18O","Free Base","N/A","CC(C)C1CCC(C)CC1=O",2.736,1,0,1]
["S3029","Malonic acid","e9","L1300-31","in 10mM DMSO",null,"USP43-NF38",null,"Others","Others","Others","Malonic acid (MOA), one of the major dicarboxylic acids (DCAs) in aerosols, has been identified experimentally and computationally to be a strong acid. Malonic acid (MOA) acts as a mediate bridge for the formation of pure SA-A-based clusters.",104.06,"141-82-2",20,192.2,20,192.2,"https://www.selleckchem.com/products/malonic-acid.html","C3H4O4","Free Base","MOA","OC(=O)CC(O)=O",-0.394,2,0,2]
["S3069","Deoxycholic acid sodium salt","f9","L1300-31","in 10mM DMSO","DMF",null,null,"Gastroenterology","GPCR19","GPCR & G Protein","Deoxycholic acid sodium salt (Sodium Deoxycholate, Sodium Desoxycholate, Cholanoic Acid, ATX-101, Kythera, Belkyra, DCA) is specifically responsible for activating the TGR5 receptor (GPCR19) that stimulates brown adipose tissue (BAT) thermogenic activity.",414.55,"302-95-4",83,200.22,83,200.22,"https://www.selleckchem.com/products/deoxycholic-acid-sodium-salt.html","C24H39NaO4","Sodium salt","Sodium Deoxycholate, Sodium Desoxycholate, Cholanoic Acid, ATX-101, Kythera, Belkyra, DCA","[Na+].CC(CCC([O-])=O)C1CCC2C3CCC4CC(O)CCC4(C)C3CC(O)C12C",2.608,0,2,4]
["S3086","Maleic acid","g9","L1300-31","in 10mM DMSO","DMF","EP10.4, USP43-NF38, IP2010",null,"Others","Decarboxylase","Metabolism","Maleic acid inhibits glutamate decarboxylase (GAD) activity, thus enhances acid sensitivity of Listeria monocytogenes. Maleic acid affects the extracellular GABA levels.",116.07,"110-16-7",23,198.16,23,198.16,"https://www.selleckchem.com/products/maleic-acid.html","C4H4O4","Free Base","N/A","OC(=O)\\C=C/C(O)=O",0.038,2,0,2]
["S3093","Pyrazole","h9","L1300-31","in 10mM DMSO","DMF","USP43-NF38",null,"Others","Others","Others","Pyrazole (1H-pyrazole) is a five membered heteroaromatic ring with two nitrogen atoms is of immense significance. Pyrazole is an indispensable anchor for design and development of new pharmacological agents.",68.08,"288-13-1",14,205.64,14,205.64,"https://www.selleckchem.com/products/pyrazole.html","C3H4N2","Free Base","1H-pyrazole","[NH]1C=CC=N1",0.273,1,1,0]
["S3101","2-Deoxy-D-ribose","a10","L1300-31","in 10mM DMSO",null,"EP10.4",null,"Others","Others","Others","2-Deoxy-D-ribose (Thyminose, Deoxyribose) is an endogenous metabolite.",134.13,"533-67-5",27,201.3,27,201.3,"https://www.selleckchem.com/products/2-deoxy-d-ribose.html","C5H10O4","Free Base","Thyminose, Deoxyribose","OCC(O)C(O)CC=O",-1.628,1,3,4]
["S3111","Pyridoxal hydrochloride","b10","L1300-31","in 10mM DMSO","DMF, PMDA","USP43-NF38",null,"Nutritional support","Others","Others","Pyridoxal hydrochloride (HQ) is an active endogenous metabolite.",203.62,"65-22-5",40,196.44,40,196.44,"https://www.selleckchem.com/products/pyridoxal-hydrochloride.html","C8H10ClNO3","Free Base","HQ","Cl.CC1=NC=C(CO)C(=C1O)C=O",0.256,2,2,2]
["S3134","D-(-)-Tartaric acid","c10","L1300-31","in 10mM DMSO","DMF,CFDA,FDA,PMDA","USP40-NF35,IP2010,JP16","018509","Others","Others","Others","D-(-)-Tartaric acid is the unnatural isomer of Tartaric acid which is an important chiral chemical building block with broad industrial and scientific applications.",150.09,"147-71-7",30,199.88,30,199.88,"https://www.selleckchem.com/products/d-tartaric-acid.html","C4H6O6","Free Base","D-Tartaric acid","OC(C(O)C(O)=O)C(O)=O",-1.664,2,2,3]
["S3141","Maleimide","d10","L1300-31","in 10mM DMSO","DMF",null,null,"Others","ADC Linker,Dyes","Others","Maleimide exhibits fluorescence quenching ability and can be used for the specific detection of thiol analytes as fluorogenic probes. Maleimide is also used for production of antibody-drug conjugate (ADC) which is used in cancer research.",97.07,"541-59-3",19,195.74,19,195.74,"https://www.selleckchem.com/products/maleimide.html","C4H3NO2","Free Base","N/A","O=C1NC(=O)C=C1",-0.395,2,1,0]
["S3143","Pyruvic acid","e10","L1300-31","in 10mM DMSO","DMF","EP10.4, USP43-NF38",null,"Nutritional support","ATPase,Casein Kinase,LDH","Metabolism","Pyruvic acid (Acetylformic acid) is an important organic chemical intermediate that plays a role in cardiomyocyte pathophysiology and therapy. Pyruvic acid markedly increases the level of lactate dehydrogenase (LDH) and creatine kinase (CK) and reduces the level of Ca2+Mg2+-ATPase and Na+K+-ATPase.",88.06,"127-17-3","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"https://www.selleckchem.com/products/pyruvic-acid.html","C3H4O3","Free Base","Acetylformic acid","CC(=O)C(O)=O",-0.329,2,0,1]
["S3152","Glutaric acid","f10","L1300-31","in 10mM DMSO",null,"EP10.4",null,"Others","Others","Others","Glutaric acid (GA) is an attractive C5 dicarboxylic acid with wide applications in the biochemical industry.",132.11,"110-94-1",26,196.81,26,196.81,"https://www.selleckchem.com/products/glutaric-acid.html","C5H8O4","Free Base","GA","OC(=O)CCCC(O)=O",0.096,2,0,4]
["S3218","Amiloxate","g10","L1300-31","in 10mM DMSO",null,"USP43-NF38",null,"Others","Anti-infection","Microbiology","Amiloxate (Amiloxiate, Isoamyl Methoxycinnamate, Isopentyl 4-methoxycinnamate, Isoamyl 4-methoxycinnamate, Isoamyl p-methoxycinnamate, Isopentyl p-methoxycinnamate) is EMA-approved chemical UV-filter used in cosmetics. Amiloxate is a cinnamic acid derivative with anti-inflammatory activity.",248.32,"71617-10-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"https://www.selleckchem.com/products/amiloxate.html","C15H20O3","Free Base","Amiloxiate, Isoamyl Methoxycinnamate, Isopentyl 4-methoxycinnamate, Isoamyl 4-methoxycinnamate, Isoamyl p-methoxycinnamate, Isopentyl p-methoxycinnamate","COC1=CC=C(C=CC(=O)OCCC(C)C)C=C1",3.717,3,0,7]
["S3311","Myosmine","h10","L1300-31","in 10mM DMSO",null,"EP10.4",null,"Others","AChR","Neuronal Signaling","Myosmine is not only one of the minor tobacco alkaloids but is also present in various foods. Myosmine has low affinity against a4b2 nicotinic acetylcholinergic receptors (nAChR) with Ki of 3300 nM.",146.19,"532-12-7",29,198.37,29,198.37,"https://www.selleckchem.com/products/myosmine.html","C9H10N2","Free Base","N/A","C1CN=C(C1)C2=CN=CC=C2",0.935,2,0,1]
["S3314","2-Methylpentanoic acid","a11","L1300-31","in 10mM DMSO","DMF, CFDA",null,null,"Others","Others","Others","2-Methylpentanoic acid (2-Methylvaleric acid, Methylpropylacetic acid) is a short-chain fatty acid that exists in various foods including cheeses, cherimoya, lamb and mutton, and so on. 2-Methylpentanoic acid is a flavor compound used for food-flavor ingredient, fragrances.",116.16,"97-61-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"https://www.selleckchem.com/products/2-methylpentanoic-acid.html","C6H12O2","Free Base","2-Methylvaleric acid, Methylpropylacetic acid","CCCC(C)C(O)=O",1.837,1,0,3]
["S3332","D-Mannosamine hydrochloride","b11","L1300-31","in 10mM DMSO","DMF",null,null,"Others","Others","Others","D-Mannosamine hydrochloride ((2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride) is an active endogenous metabolite.",215.63,"5505-63-5",43,199.42,43,199.42,"https://www.selleckchem.com/products/d-mannosamine-hydrochloride.html","C6H14ClNO5","Hydrochloride","(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride","Cl.NC(C=O)C(O)C(O)C(O)CO",-2.699,1,5,5]
["S3341","Palmitoleic acid","c11","L1300-31","in 10mM DMSO",null,"EP10.4",null,"Angiology","AMPK","PI3K/Akt/mTOR","Palmitoleic acid (POA, Palmitoleate) stimulates the uptake of glucose in liver through activation of AMPK and FGF-21, dependent on PPARα.",254.41,"373-49-9","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"https://www.selleckchem.com/products/palmitoleic-acid.html","C16H30O2","Free Base","POA, Palmitoleate","CCCCCC\\C=C/CCCCCCCC(O)=O",5.948,1,0,13]
["S3360","Bis(2-ethylhexyl) phthalate","d11","L1300-31","in 10mM DMSO",null,"USP43-NF38",null,"Others","DNA/RNA Synthesis","DNA Damage/DNA Repair","Bis(2-ethylhexyl) phthalate (Dioctyl phthalate, DOP, Diplast O, ESBO-D 82, Ergoplast FDO, Ergoplast FDO-S, Etalon) induces DNA strand breaks and gene expression alterations in larval zebrafish Danio rerio.",390.56,"117-81-7","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"https://www.selleckchem.com/products/bis-2-ethylhexyl-phthalate.html","C24H38O4","Phthalate","Dioctyl phthalate, DOP, Diplast O, ESBO-D 82, Ergoplast FDO, Ergoplast FDO-S, Etalon","CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC",7.574,4,0,16]
["S3371","N-Acetyl-D-mannosamine","e11","L1300-31","in 10mM DMSO","DMF",null,null,"Others","Others","Others","N-Acetyl-D-mannosamine (ManNAc, N-acetyl-beta-mannosamine), a precursor of a sialic acid, improves the age-dependent attenuation of synaptic transmission and long-term potentiation (LTP). N-Acetyl-D-mannosamine treatment is a potential therapeutic application for cognitive dysfunction.",221.21,"7772-94-3",44,198.91,44,198.91,"https://www.selleckchem.com/products/n-acetyl-d-mannosamine.html","C8H15NO6","Free Base","ManNAc, N-acetyl-beta-mannosamine","CC(=O)NC1C(O)OC(CO)C(O)C1O",-2.782,2,4,2]
["S3743","Oxiglutatione","f11","L1300-31","in 10mM DMSO","FDA, PMDA",null,"022193","Others","Others","Others","Oxiglutatione (Oxidized glutathione, Glutathione disulfide, GSSG, Bi(glutathion-S-yl)) is the oxidized disulfide form of glutathione (GSH) with potential protective activity.",612.63,"27025-41-8",7,11.43,100,163.23,"https://www.selleckchem.com/products/oxiglutatione.html","C20H32N6O12S2","Free Base","Oxidized glutathione, Glutathione disulfide, GSSG, Bi(glutathion-S-yl)","NC(CCC(=O)NC(CSSCC(NC(=O)CCC(N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O",-9.385,8,6,21]
["S4417","Ceftaroline Fosamil","g11","L1300-31","in 10mM DMSO","FDA, DMF, EMA, NDC",null,200327,"Infection","Anti-infection","Immunology & Inflammation","Ceftaroline fosamil (CX-0903, DSP-5990, PPI-0903, TAK-599, Teflaro, Zinforo) is a cephalosporin with activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).",744.74,"400827-46-5",73,98.02,"<1",0,"https://www.selleckchem.com/products/ceftaroline-fosamil.html","C24H25N8O10PS4","Free Base","CX-0903, DSP-5990, PPI-0903, TAK-599, Teflaro, Zinforo","CCO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)SC3=NC(=CS3)C4=CC=[N+](C)C=C4)C5=NSC(=N5)N[P](O)(O)=O.CC([O-])=O",-0.454,8,2,11]
["S5248","Apatinib","h11","L1300-31","in 10mM DMSO","CFDA",null,null,"Cancer","Apoptosis related,Autophagy,c-Kit,c-RET,Src,VEGFR","Protein Tyrosine Kinase","Apatinib (Rivoceranib, YN968D1) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib induces both autophagy and apoptosis.",397.47,"811803-05-1",79,198.76,"<1",0,"https://www.selleckchem.com/products/apatinib.html","C24H23N5O","Free Base","Rivoceranib, YN968D1","O=C(NC1=CC=C(C=C1)C2(CCCC2)C#N)C3=C(NCC4=CC=NC=C4)N=CC=C3",3.578,3,2,6]
["S5645","Hemin","a2","L1300-32","in 10mM DMSO","DMF, PMDA",null,null,"Hematology","Heme Oxygenase","Apoptosis","Hemin (protohemin) is an iron-containing porphyrin used in the management of porphyria attacks, particularly in acute intermittent porphyria.Hemin is an Heme oxygenase (HO)-1 inducer.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!",651.94,"16009-13-5",20,30.68,"<1",0,"https://www.selleckchem.com/products/hemin.html","C34H32ClFeN4O4","Free Base","protohemin","CC1=C(CCC(O)=O)C\\2=N\\C1=C/C3=C(C=C)C(=C4\\C=C5/N=C(/C=C6\\N([Fe](Cl)[N]34)\\C(=C2)C(=C6C)CCC(O)=O)C(=C5C=C)C)C",6.404,4,0,8]
["S6358","Indole","b2","L1300-32","in 10mM DMSO","DMF, NDC","USP43-NF38",null,"Others","Others","Others","Indole (2,3-Benzopyrrole) is an aromatic heterocyclic organic compound widely distributed in the natural environment and can be produced by a variety of bacteria.",117.15,"120-72-9",23,196.33,-1,0,"https://www.selleckchem.com/products/indole.html","C8H7N","Free Base","2,3-Benzopyrrole","[NH]1C=CC2=C1C=CC=C2",2.123,0,1,0]
["S6367","3-Hydroxybenzoic acid","c2","L1300-32","in 10mM DMSO","NDC",null,null,"Others","Others","Others","3-Hydroxybenzoic acid (m-Hydroxybenzoic acid, 3-Carboxyphenol, m-Salicylic acid) is used as an intermediate in the synthesis of plasticisers, resins, pharmaceuticals, etc.",138.12,"99-06-9",28,202.72,-1,0,"https://www.selleckchem.com/products/3-hydroxybenzoic-acid.html","C7H6O3","Free Base","m-Hydroxybenzoic acid, 3-Carboxyphenol, m-Salicylic acid","OC(=O)C1=CC=CC(=C1)O",1.217,1,1,1]
["S6890","Trypan Blue","d2","L1300-32","in 10mM DMSO","FDA, DMF, NDC","USP43-NF38",null,"Others","Dyes","Others","Trypan Blue (Visionblue, Diphenyl Blue, Direct Blue 14) is a colorimetric dye that stains dead cells with a blue color easily observed using light microscopy at low resolution.",960.81,"72-57-1",100,104.08,100,104.08,"https://www.selleckchem.com/products/trypan-blue.html","C34H24N6Na4O14S4","Free Base","Visionblue, Diphenyl Blue, Direct Blue 14","[Na+].[Na+].[Na+].[Na+].CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N=NC3=C(O)C4=C(N)C=C(C=C4C=C3[S]([O-])(=O)=O)[S]([O-])(=O)=O)C)N=NC5=C(O)C6=C(N)C=C(C=C6C=C5[S]([O-])(=O)=O)[S]([O-])(=O)=O",-2.749,4,4,9]
["S6908","DOTAP chloride","e2","L1300-32","in 10mM DMSO","DMF",null,null,"Others","Others","Others","DOTAP chloride (1,2-Dioleoyl-3-trimethylammonium-propane chloride) is an effective cationic lipid widely used as a liposomal transfection reagent. DOTAP is also a strong activator of the innate immune system in animal cells and a good candidate as an elicitor for the study of plant immunity.",698.54,"132172-61-3",100,143.16,"<1",0,"https://www.selleckchem.com/products/dotap-chloride.html","C42H80ClNO4","Chloride","1,2-Dioleoyl-3-trimethylammonium-propane chloride","[Cl-].CCCCCCCC\\C=C/CCCCCCCC(=O)OCC(C[N+](C)(C)C)OC(=O)CCCCCCC\\C=C/CCCCCCCC",10.13,4,0,37]
["S6948","Lanreotide","f2","L1300-32","in 10mM DMSO","FDA, DMF, NDC",null,null,"Endocrinology/Metabolic Disease","GHSR","Endocrinology & Hormones","Lanreotide (Laromustine, Angiopeptin, BIM 23014, Dermopeptin, Ipstyl, ITM-014, Somatulina, Somatuline, Lanreotidum), an analog of the native somatostatin peptide, is a physiological inhibitor of growth hormone (GH). Lanreotide also has antitumoral effects.",1096.32,"108736-35-2",100,91.21,100,91.21,"https://www.selleckchem.com/products/lanreotide.html","C54H69N11O10S2","Free Base","Laromustine, Angiopeptin, BIM 23014, BIM 23014C, BM 23014, Dermopeptin, Ipstyl, ITM-014, ITM-014T, Somatulina, Somatuline, Lanreotidum","CC(C)C1NC(=O)C(CCCCN)NC(=O)C(CC2=C[NH]C3=C2C=CC=C3)NC(=O)C(CC4=CC=C(O)C=C4)NC(=O)C(CSSCC(NC1=O)C(=O)NC(C(C)O)C(N)=O)NC(=O)C(N)CC5=CC6=CC=CC=C6C=C5",1.704,8,13,17]
["S6955","Insulin (human)","g2","L1300-32","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA",null,"022472","Endocrinology/Metabolic Disease","IGF-1R","Protein Tyrosine Kinase","Insulin (human) (Insulin regular) is a polypeptide hormone that regulates the level of glucose. Insulin is commonly used to treat hyperglycemia in patients with diabetes. Potency: 29 units/mg.",5807.57,"11061-68-0",100,17.22,"<1",0,"https://www.selleckchem.com/products/insulin.html","C257H383N65O77S6","Free Base","Insulin regular",0,0.734,0,0,0]
["S6957","β-Elemene","h2","L1300-32","in 10mM DMSO","NMPA",null,null,"Cancer","Apoptosis related,Autophagy","Apoptosis","β-Elemene ((-)-β-Elemene, Levo-β-elemene) is a sesquiterpene compound extracted from the herb Curcuma Rhizoma with antitumor activities. β-elemene can inhibit cell proliferation, arrest the cell cycle, and induce cell apoptosis or autophagy.",204.35,"515-13-9","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"https://www.selleckchem.com/products/b-elemene.html","C15H24","Free Base","(-)-β-Elemene, Levo-β-elemene","CC(=C)C1CCC(C)(C=C)C(C1)C(C)=C",4.788,0,0,3]
["S6958","Treosulfan","a3","L1300-32","in 10mM DMSO","DMF, EMA, HMA",null,null,"Cancer","DNA alkylator","DNA Damage/DNA Repair","Treosulfan (NSC 39069, Treosulphan) is an alkylating agent used for conventional and high-dose chemotherapy regimens. Treosulfan is potently cytotoxic against pancreatic cancer cell lines.",278.3,"299-75-2",56,201.22,56,201.22,"https://www.selleckchem.com/products/treosulfan.html","C6H14O8S2","Free Base","NSC 39069, Treosulphan","C[S](=O)(=O)OCC(O)C(O)CO[S](C)(=O)=O",-1.953,2,2,7]
["S6959","Perhexiline maleate","b3","L1300-32","in 10mM DMSO","DMF, CFDA",null,null,"Cardiovascular Disease","CPT","Metabolism","Perhexiline maleate is a potent inhibitor of carnitine palmitoyltransferase 1 (CPT1) with IC50s of 77 μM and 148 μM for rat heart CPT1 and liver CPT1, respectively, and also inhibits carnitine palmitoyltransferase 2 (CPT2).",393.56,"6724-53-4",78,198.19,"<1",0,"https://www.selleckchem.com/products/perhexiline-maleate.html","C23H39NO4","Maleate","N/A","OC(=O)\\C=C/C(O)=O.C1CCC(CC1)C(CC2CCCCN2)C3CCCCC3",3.054,2,1,6]
["S9103","Ginsenoside Ro","c3","L1300-32","in 10mM DMSO",null,"EP10.4",null,"Hematology","Others","Others","Ginsenoside Ro (Chikusetsusaponin V), one of the high-abundance saponins in ginseng, is widely used as a dietary supplement and has many health-promoting effects.",957.11,"34367-04-9",100,104.48,100,104.48,"https://www.selleckchem.com/products/ginsenoside-ro.html","C48H76O19","Free Base","Chikusetsusaponin V","CC1(C)CCC2(CCC3(C)C(=CCC4C5(C)CCC(OC6OC(C(O)C(O)C6OC7OC(CO)C(O)C(O)C7O)C(O)=O)C(C)(C)C5CCC34C)C2C1)C(=O)OC8OC(CO)C(O)C(O)C8O",1.151,8,10,10]
["S9521","Pentostatin","d3","L1300-32","in 10mM DMSO","FDA, DMF, NDC, PMDA",null,null,"Cancer","Adenosine Deaminase,DNA/RNA Synthesis","Neuronal Signaling","Pentostatin(CI-825,Deoxycoformycin) is a potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.",268.27,"53910-25-1",54,201.29,54,201.29,"https://www.selleckchem.com/products/pentostatin.html","C11H16N4O4","Free Base","CI-825,Deoxycoformycin","OCC1OC(CC1O)[N]2C=NC3=C2NC=NCC3O",-1.965,3,4,2]
["S9656","Enarodustat (JTZ-951)","e3","L1300-32","in 10mM DMSO","PMDA",null,null,"Others","HIF","Angiogenesis","Enarodustat (JTZ-951) is a potent and orally active HIF prolyl hydroxylase inhibitor with IC50 of 0.22 μM for PHD2 and EC50 of 5.7 μM for EPO release from Hep3B cells. Enarodustat has the potential for the treatment of renal anemia.",340.33,"1262132-81-9",68,199.81,"<1",0,"https://www.selleckchem.com/products/enarodustat.html","C17H16N4O4","Free Base","N/A","OC(=O)CNC(=O)C1=C(O)C=C(CCC2=CC=CC=C2)[N]3N=CN=C13",1.511,4,2,6]
["S9674","Saroglitazar","f3","L1300-32","in 10mM DMSO","marketed in India",null,null,"Metabolic Disease","PPAR","Metabolism","Saroglitazar (Lipaglyn, ZYH1) is an agonist of peroxisome proliferator-activated receptor (PPAR) with EC50 of 0.65 pM and 3 nM for hPPARα and hPPARγ in HepG2 cells, respectively.",439.57,"495399-09-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"https://www.selleckchem.com/products/saroglitazar.html","C25H29NO4S","Free Base","Lipaglyn, ZYH1","CCOC(CC1=CC=C(OCC[N]2C(=CC=C2C3=CC=C(SC)C=C3)C)C=C1)C(O)=O",5.349,3,0,11]
["S9700","Tapinarof","g3","L1300-32","in 10mM DMSO","FDA,NDC,PMDA,CFDA",null,"215272","Inflammation/Immunology","AhR,Apoptosis related","Metabolism","Tapinarof (GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505) is a natural agonist of aryl hydrocarbon receptor (AhR) and induces nuclear translocation of AhR in immortalized keratinocytes (HaCaT) with EC50 of 0.16 nM. Tapinarof induces cellular apoptosis in CD4+ T cells in a dosedependent manner with IC50 of 5.2 μM.",254.32,"79338-84-4",51,200.53,"<1",0,"https://www.selleckchem.com/products/tapinarof.html","C17H18O2","Free Base","GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505","CC(C)C1=C(O)C=C(\\C=C\\C2=CC=CC=C2)C=C1O",4.526,0,2,3]
["S9712","Fluzoparib (SHR-3162)","h3","L1300-32","in 10mM DMSO","CFDA",null,null,"Cancer","PARP","DNA Damage/DNA Repair","Fluzoparib (SHR3162, HS10160) is a potent Poly (ADP-ribose) polymerase (PARP) inhibitor that shows anti-tumor activity, with an IC50 of 1.46±0.72 nM for PARP1.",472.4,"1358715-18-0",94,198.98,"<1",0,"https://www.selleckchem.com/products/fluzoparib.html","C22H16F4N6O2","Free Base","HS10160","FC1=CC=C(CC2=NNC(=O)C3=C2C=CC=C3)C=C1C(=O)N4CC[N]5N=C(N=C5C4)C(F)(F)F",2.757,5,1,4]
["S0717","Varenicline (CP 526555) dihydrochloride","a4","L1300-32","in 10mM DMSO","FDA, DMF, EMA, NDC, PMDA",null,201920,"Others","AChR","Neuronal Signaling","Varenicline (CP 526555, Chantix, Champix,CP 526555 dihydrochloride) dihydrochloride is a potent, partial agonist of α4β2 nicotinic acetylcholine receptor (nAChR) and α3β4 nAChR with EC50 of 2.3 μM and 55 μM, respectively. Varenicline dihydrochloride is a potent, full agonist of α7 nAChRs with EC50 of 18 μM. Varenicline is a prescription medication used for smoking cessation.",284.18,"866823-63-4",57,200.58,57,200.58,"http://www.selleckchem.com/products/varenicline-dihydrochloride.html","C13H15Cl2N3","Dihydrochloride","Chantix, Champix,CP 526555 dihydrochloride","Cl.Cl.C1NCC2CC1C3=CC4=NC=CN=C4C=C23",1.802,2,1,0]
["S1711","Crotamiton","b4","L1300-32","in 10mM DMSO","FDA, DMF, NDC, CFDA, PMDA","EP10.4, USP43-NF38","087204","Parasite","Others","Angiogenesis","Crotamiton is a drug that is used as a scabicidal (for treating scabies) and an antipruritic",203.28,"483-63-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/Crotamiton.html","C13H17NO","Free Base","N/A","CCN(C(=O)\\C=C\\C)C1=CC=CC=C1C",3.091,1,0,3]
["S1924","Indocyanine green","c4","L1300-32","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","USP43-NF38","040811","Diagnosis","Others","Others","Indocyanine green(Cardiogreen) is a cyanine dye used in medical diagnostics. It is used for determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography.",774.96,"3599-32-4",155,200.01,"<1",0,"http://www.selleckchem.com/products/Indocyanine-green(Cardiogreen).html","C43H47N2NaO6S2","Free Base","Cardiogreen","[Na+].CC1(C)C(=C/C=C/C=C/C=C/C2=[N+](CCCC[S]([O-])(=O)=O)C3=C(C4=C(C=CC=C4)C=C3)C2(C)C)/N(CCCC[S]([O-])(=O)=O)C5=C1C6=C(C=CC=C6)C=C5",4.068,0,0,14]
["S1997","Liranaftate","d4","L1300-32","in 10mM DMSO","CFDA, PMDA",null,null,"Infection","Fungal","Microbiology","Liranaftate (M-732,Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities.",328.43,"88678-31-3",25,76.12,"<1",0,"http://www.selleckchem.com/products/liranaftate.html","C18H20N2O2S","Free Base","M-732,Piritetrate","COC1=NC(=CC=C1)N(C)C(=S)OC2=CC3=C(CCCC3)C=C2",6.319,3,0,5]
["S3380","Tecovirimat","e4","L1300-32","in 10mM DMSO","FDA, NDC",null,"208627","Infection","Antiviral","Immunology & Inflammation","Tecovirimat (Arestvyr, SIGA-246, ST-246, TPOXX) is an antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs. Tecovirimat is developed for the treatment of smallpox infection.",376.33,"869572-92-9",75,199.29,"<1",0,"http://www.selleckchem.com/products/tecovirimat.html","C19H15F3N2O3","Free Base","Arestvyr, SIGA-246, ST-246, TPOXX","FC(F)(F)C1=CC=C(C=C1)C(=O)NN2C(=O)C3C4C=CC(C5CC45)C3C2=O",2.018,3,1,3]
["S3496","Lefamulin acetate (Xenleta)","f4","L1300-32","in 10mM DMSO","FDA, EMA",null,"211672","Infection/Respiratory Disease","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Bacterial","Immunology & Inflammation","Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer.",567.78,"1350636-82-6",100,176.12,100,176.12,"http://www.selleckchem.com/products/lefamulin-acetate.html","C30H49NO7S","Free Base","BC-3781 acetate","CC1CCC23CCC(=O)C2C1(C)C(CC(C)(C=C)C(O)C3C)OC(=O)CSC4CCC(N)CC4O.CC(O)=O",0.083,4,3,6]
["S3498","Ecamsule.2Na","g4","L1300-32","in 10mM DMSO","DMF,FDA",null,"021471","Others","Others","Others","Ecamsule.2Na is the Sodium salt form of Ecamsule. Ecamsule is an active ingredient of sunscreens that protects the skin from sunburn and erythema.",606.66,"90458-75-6",100,164.84,100,164.84,"http://www.selleckchem.com/products/ecamsule-2na.html","C28H32Na2O8S2","Free Base","N/A","[Na+].[Na+].CC1(C)C2CCC1(C[S]([O-])(=O)=O)C(=O)C2=CC3=CC=C(C=C3)C=C4C5CCC(C[S]([O-])(=O)=O)(C4=O)C5(C)C",-0.638,2,0,6]
["S3499","Monocaprylin","h4","L1300-32","in 10mM DMSO","FDA",null,"019368","Gastroenterology","Bacterial","Immunology & Inflammation","Monocaprylin (2,3-dihydroxypropyl octanoate, Monoctanoin, 1-Octanoyl-rac-glycerol, MC) exhibits an excellent antibacterial activity against Staphylococcus aureus and Escherichia coli.",218.29,"26402-26-6",44,201.57,"<1",0,"http://www.selleckchem.com/products/monocaprylin.html","C11H22O4","Free Base","2,3-dihydroxypropyl octanoate, Monoctanoin, 1-Octanoyl-rac-glycerol","CCCCCCCC(=O)OCC(O)CO",1.918,2,2,10]
["S3501","Perflubron","a5","L1300-32","in 10mM DMSO","FDA","USP43-NF38","020091","Cardiovascular Disease/Gastroenterology/Infection","Immunology & Inflammation related","Immunology & Inflammation","Perflubron (1-Bromoperfluorooctane, Perfluorooctyl bromide, Oxygent, PFOB) exhibits anti-inflammatory activity thus decreases cytokine production in human alveolar macrophages. Perflubron also attenuates oxidative damage to both biological and nonbiological systems which is independent of its anti-inflammatory properties.",498.96,"423-55-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/perflubron.html","C8BrF17","Free Base","1-Bromoperfluorooctane, Perfluorooctyl bromide, Oxygent, PFOB","FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br",5.546,0,0,7]
["S3577","Rhodamine 123","b5","L1300-32","in 10mM DMSO","DMF",null,null,"Diagnosis","ATPase,Dyes","Transmembrane Transporters","Rhodamine 123 (RH-123, R-22420) is a fluorescent cationic dye used to label mitochondria in living cells. Rhodamine 123 inhibits ADP-stimulated respiration of mitochondria with Ki = 12 μM and ATPase activity of inverted inner membrane vesicles with Ki of 126 μM and partially purified F1-ATPase with Ki of 177 μM.",380.82,"62669-70-9",76,199.57,"<1",0,"http://www.selleckchem.com/products/rhodamine-123.html","C21H17ClN2O3","Free Base","RH-123, R-22420","Cl.COC(=O)C1=CC=CC=C1C2=C3C=CC(=N)C=C3OC4=C2C=CC(=C4)N",3.216,3,1,3]
["S3587","Mebrofenin","c5","L1300-32","in 10mM DMSO","FDA, DMF, NDC","USP43-NF38","078242","Diagnosis","Others","Others","Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA) that is available as a ready to use the kit for radio-labeling with Technetium-99m (Tc-99m). Tc-99m Mebrofenin is used clinical for hepatobiliary scintigraphy.",387.23,"78266-06-5",77,198.85,"<1",0,"http://www.selleckchem.com/products/mebrofenin.html","C15H19BrN2O5","Free Base","SQ 26962","CC1=C(Br)C(=C(NC(=O)CN(CC(O)=O)CC(O)=O)C(=C1)C)C",-0.909,3,1,7]
["S3588","Hexylene glycol","d5","L1300-32","in 10mM DMSO",null,"USP43-NF38",null,"Others","Fungal","Microbiology","Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) is an oxygenated solvent derived from acetone that has been used widely in industrial chemicals and cosmetics. Hexylene glycol exhibits antibacterial and antifungal properties.",118.17,"107-41-5","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/hexylene-glycol.html","C6H14O2","Free Base","HG, 2-Methyl-2,4-pentanediol, MPD","CC(O)CC(C)(C)O",0.124,0,1,2]
["S3589","Bendazol","e5","L1300-32","in 10mM DMSO","CFDA, PMDA",null,null,"Cardiovascular Disease","HIF,NOS","Immunology & Inflammation","Bendazol (2-Benzylbenzimidazole, Dibazol, Dibazole, Bendazole, Tromasedan) is a hypotensive drug that enhances NO synthase activity in renal glomeruli and collecting tubules. Bendazol inhibits the progression of form-deprivation myopia (FDM) and suppresses the upregulation of HIF-1α.",208.26,"621-72-7",42,201.67,"<1",0,"http://www.selleckchem.com/products/bendazol.html","C14H12N2","Free Base","2-Benzylbenzimidazole, Dibazol, Dibazole, Bendazole, Tromasedan","C(C1=NC2=CC=CC=C2[NH]1)C3=CC=CC=C3",3.305,1,1,2]
["S3590","Triolein","f5","L1300-32","in 10mM DMSO","DMF","EP10.4",null,"Others","Interleukins,MMP,ROS","Proteases","Triolein is an inhibitor of metalloproteinase-1 (MMP-1) and reduces both the expression of IL-6 and ROS generation in irradiated keratinocytes.",885.43,"122-32-7","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/triolein.html","C57H104O6","Free Base","N/A","CCCCCCCC\\C=C/CCCCCCCC(=O)OCC(COC(=O)CCCCCCC\\C=C/CCCCCCCC)OC(=O)CCCCCCC\\C=C/CCCCCCCC",20.925,6,0,53]
["S3592","4-Phenylbutyric acid (4-PBA)","g5","L1300-32","in 10mM DMSO","DMF",null,null,"Metabolic Disease","Autophagy,HDAC","DNA Damage/DNA Repair","4-Phenylbutyric acid (4-PBA, Benzenebutyric acid) is a histone deacetylase (HDAC) inhibitor and a key epigenetic inducer of anti-HCV hepatic hepcidin. 4-Phenylbutyric acid inhibits LPS-induced inflammation through regulating endoplasmic-reticulum (ER) stress and autophagy in acute lung injury models.",164.2,"1821-12-1",33,200.97,"<1",0,"http://www.selleckchem.com/products/4-phenylbutyric-acid-4-pba-.html","C10H12O2","Free Base","Benzenebutyric acid","OC(=O)CCCC1=CC=CC=C1",2.407,1,0,4]
["S3593","Rhodamine 6G","h5","L1300-32","in 10mM DMSO",null,"USP43-NF38",null,"Diagnosis","Dyes,Mitochondrial Metabolism","Metabolism","Rhodamine 6G (R6G, Basic Red 1, Rhodamine 590) is a fluorescence tracer that binds to mitochondria, thus reducing the intact mitochondria number and inhibiting mitochondrial metabolic activity.",479.01,"989-38-8",96,200.41,"<1",0,"http://www.selleckchem.com/products/rhodamine-6g.html","C28H31ClN2O3","Free Base","R6G, Basic Red 1, Rhodamine 590","[Cl-].CCNC1=CC2=C(C=C1C)C(=C3C=C(C)C(C=C3O2)=[NH+]CC)C4=CC=CC=C4C(=O)OCC",2.797,3,1,7]
["S3594","Adipic acid","a6","L1300-32","in 10mM DMSO","DMF","EP10.4, USP43-NF38",null,"Others","Others","Others","Adipic acid (Hexanedioic acid) is an important dicarboxylic acid used for the manufacture of nylon and polyurethane plastics.",146.14,"124-04-9",29,198.44,29,198.44,"http://www.selleckchem.com/products/adipic-acid.html","C6H10O4","Free Base","Hexanedioic acid","OC(=O)CCCCC(O)=O",0.553,2,0,5]
["S3595","D-Gluconic acid","b6","L1300-32","in 10mM DMSO","DMF, CFDA","USP43-NF38",null,"Nutritional support","Fungal","Microbiology","D-Gluconic acid is an antifungal agent.",196.16,"526-95-4","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/d-gluconic-acid.html","C6H12O7","Free Base","N/A","OCC(O)C(O)C(O)C(O)C(O)=O",-2.813,1,5,5]
["S3597","3-Phenoxybenzoic acid","c6","L1300-32","in 10mM DMSO",null,"USP43-NF38",null,"Diagnosis","Others","Others","3-phenoxybenzoic acid (3-PBA), an intermediate metabolite of pyrethroids, is more toxic than its parent compounds and has been detected in milk, soil, and human urine.",214.22,"3739-38-6",43,200.73,"<1",0,"http://www.selleckchem.com/products/3-phenoxybenzoic-acid.html","C13H10O3","Free Base","3-PBA, m-phenoxybenzoic acid","OC(=O)C1=CC(=CC=C1)OC2=CC=CC=C2",3.019,2,0,3]
["S3598","Sucrose","d6","L1300-32","in 10mM DMSO","FDA, DMF, CFDA, NDC","EP10.4, USP43-NF38, KP Ⅹ, JP17, IP2010","078215","Others","Others","Others","Sucrose (D-(+)-Saccharose), a common sugar produced naturally in plants, is a disaccharide, a molecule composed of two monosaccharides:glucose and fructose.",342.3,"57-50-1",68,198.66,"<1",0,"http://www.selleckchem.com/products/sucrose.html","C12H22O11","Free Base","D-(+)-Saccharose","OCC1OC(OC2(CO)OC(CO)C(O)C2O)C(O)C(O)C1O",-4.311,3,8,5]
["S3599","Resazurin sodium","e6","L1300-32","in 10mM DMSO",null,"USP43-NF38",null,"Diagnosis","Dyes","Others","Resazurin sodium (Resazurin sodium salt, Diazoresorcinol sodium) is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.",251.17,"62758-13-8",50,199.07,50,199.07,"http://www.selleckchem.com/products/resazurin-sodium.html","C12H6NNaO4","Sodium","Resazurin sodium salt, Diazoresorcinol sodium","[Na+].[O-]C1=CC2=C(C=C1)[N+](=C3C=CC(=O)C=C3O2)[O-]",0.085,2,0,0]
["S3913","Pimethixene maleate","f6","L1300-32","in 10mM DMSO","approved for use in Brazil",null,null,"Respiratory Disease","5-HT Receptor,AChR,Adrenergic Receptor,Dopamine Receptor,Histamine Receptor","Neuronal Signaling","Pimethixene (Pimetixene) maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimethixene maleate inhibits 5-HT2A, 5-HT2B, 5-HT2C, 5-HT1A, 5-HT1B, 5-HT6, 5-HT7, Adrenergic α-1A, Dopamine D1 Receptor, Dopamine D2 Receptor, Dopamine D4.4 Receptor, Histamine H1 Receptor, Muscarinic M1 and Muscarinic M2 with pKi of 10.22, 10.44, 8.42, 7.63, < 5, 7.30, 7.28, 7.61, 6.37, 8.19, 7.54, 10.14, 8.61 and 9.38, respectively.",409.5,"13187-06-9",82,200.24,"<1",0,"http://www.selleckchem.com/products/pimethixene-maleate.html","C23H23NO4S","Maleate","Pimetixene maleate","CN1CCC(CC1)=C2C3=CC=CC=C3SC4=CC=CC=C24.OC(=O)\\C=C/C(O)=O",1.498,2,0,2]
["S4097","Dydrogesterone","g6","L1300-32","in 10mM DMSO","DMF, PMDA","EP10.4,USP43-NF38, KP Ⅹ, JP17, IP2010",null,"Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Dydrogesterone (NSC 92336) is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus.",312.45,"152-62-5",63,201.63,"<1",0,"http://www.selleckchem.com/products/dydrogesterone.html","C21H28O2","Free Base","NSC 92336","CC(=O)C1CCC2C3C=CC4=CC(=O)CCC4(C)C3CCC12C",3.415,2,0,1]
["S4418","Phenol Red sodium salt","h6","L1300-32","in 10mM DMSO","DMF, CFDA, PMDA","EP10.4, USP43-NF38, KP Ⅹ, IP2010",null,"Diagnosis","Dyes,Estrogen/progestogen Receptor","Others","Phenol Red sodium salt (Phenolsulfonephthalein sodium salt) is used ubiquitously as a pH indicator in tissue culture media ranging from 6.8 (yellow) to 8.2 (red). Phenol red binds to the estrogen receptor of MCF-7 human breast cancer cells.",376.36,"34487-61-1",75,199.28,15,39.86,"http://www.selleckchem.com/products/phenol-red-sodium-salt.html","C19H13NaO5S","Sodium salt","Phenolsulfonephthalein sodium salt","[Na+].OC1=CC=C(C=C1)C2(O[S](=O)(=O)C3=CC=CC=C23)C4=CC=C([O-])C=C4",2.82,1,1,2]
["S4419","Ensulizole","a7","L1300-32","in 10mM DMSO","NDC","USP43-NF38",null,"Others","ROS","Immunology & Inflammation","Ensulizole (PBSA), a water soluble sunscreen ingredient, is a sulfonated UV absorber which is characterized by intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation.",274.3,"27503-81-7",5,18.23,"<1",0,"http://www.selleckchem.com/products/ensulizole.html","C13H10N2O3S","Free Base","PBSA","O[S](=O)(=O)C1=CC2=C(C=C1)N=C([NH]2)C3=CC=CC=C3",2.603,1,1,2]
["S4423","Emamectin Benzoate","b7","L1300-32","in 10mM DMSO","approved for use in America and Canada",null,null,"Parasite","Apoptosis related,DNA/RNA Synthesis,GABA Receptor","Neuronal Signaling","Emamectin Benzoate (EMB, MK-244) activates gamma-amino butyric acid (GABA) transporter. Emamectin Benzoate induces of reactive oxygen species (ROS)-mediated DNA damage and apoptosis.",1008.24,"155569-91-8",100,99.18,"<1",0,"http://www.selleckchem.com/products/emamectin-benzoate.html","C56H81NO15","Free Base","EMB, MK-244","CCC(C)C1OC2(CC3CC(C\\C=C(C)\\C(OC4CC(OC)C(OC5CC(OC)C(NC)C(C)O5)C(C)O4)C(C)/C=C/C=C/6COC7C(O)C(=CC(C(=O)O3)C67O)C)O2)C=CC1C.OC(=O)C8=CC=CC=C8",3.589,12,2,10]
["S4425","Rifamycin S","c7","L1300-32","in 10mM DMSO","DMF",null,null,"Infection","Antibiotics,Bacterial,ROS","Immunology & Inflammation","Rifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation.",695.75,"13553-79-2",100,143.73,"<1",0,"http://www.selleckchem.com/products/rifamycin-s.html","C37H45NO12","Free Base","N/A","COC1\\C=C\\OC2(C)OC3=C(C2=O)C4=C(C(=C3C)O)C(=O)C(=CC4=O)NC(=O)\\C(=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)C",2.779,9,4,3]
["S4426","Sacubitril hemicalcium salt","d7","L1300-32","in 10mM DMSO","FDA, DMF, EMA, NDC, PMDA",null,"207620","Cardiovascular Disease","Neprilysin","Proteases","Sacubitril (AHU-377) hemicalcium salt, a component of the heart failure medicine LCZ696, is a potent inhibitor of neprilysin (neutral endopeptidase, NEP).",861.04,"1369773-39-6",100,116.14,"<1",0,"http://www.selleckchem.com/products/sacubitril-hemicalcium-salt.html","C48H56CaN2O10","Hemicalcium salt","AHU-377 hemicalcium salt","[Ca++].CCOC(=O)C(C)CC(CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC([O-])=O.CCOC(=O)C(C)CC(CC3=CC=C(C=C3)C4=CC=CC=C4)NC(=O)CCC([O-])=O",4.569,6,2,24]
["S4427","Tenofovir alafenamide hemifumarate","e7","L1300-32","in 10mM DMSO","FDA, DMF, EMA, CFDA, NDC, PMDA",null,"210251","Infection","Reverse Transcriptase","Microbiology","Tenofovir alafenamide (TAF, GS-7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection.",1069,"1392275-56-7",100,93.55,50,46.77,"http://www.selleckchem.com/products/tenofovir-alafenamide-hemifumarate.html","C46H62N12O14P2","Hemifumarate","TAF hemifumarate, GS-7340 hemifumarate","CC(C)OC(=O)C(C)N[P](=O)(COC(C)C[N]1C=NC2=C(N)N=CN=C12)OC3=CC=CC=C3.CC(C)OC(=O)C(C)N[P](=O)(COC(C)C[N]4C=NC5=C(N)N=CN=C45)OC6=CC=CC=C6.OC(=O)\\C=C\\C(O)=O",3.092,18,4,26]
["S4428","Tenofovir alafenamide fumarate","f7","L1300-32","in 10mM DMSO","FDA, DMF, EMA, CFDA, NDC, PMDA",null,"210251","Infection","Reverse Transcriptase","Microbiology","Tenofovir alafenamide (TAF, GS-7340) fumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection.",592.54,"379270-38-9",100,168.76,10,16.88,"http://www.selleckchem.com/products/tenofovir-alafenamide-fumarate.html","C25H33N6O9P","Fumarate","TAF fumarate, GS-7340 fumarate","CC(C)OC(=O)C(C)N[P](=O)(COC(C)C[N]1C=NC2=C(N)N=CN=C12)OC3=CC=CC=C3.OC(=O)\\C=C\\C(O)=O",1.565,10,2,14]
["S4429","Edoxaban","g7","L1300-32","in 10mM DMSO","FDA, DMF, EMA, NDC, PMDA",null,"206316","Cardiovascular Disease","Factor Xa","Metabolism","Edoxaban (DU-176b, Savaysa), an antithrombotic agent, is a selective, potent and orally active inhibitor of factor Xa (FXa) with Ki of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively.",548.06,"480449-70-5",10,18.25,"<1",0,"https://www.selleckchem.com/products/edoxaban-du-176b.html","C24H30ClN7O4S","Free Base","DU-176b, Savaysa","CN1CCC2=C(C1)SC(=N2)C(=O)NC3CC(CCC3NC(=O)C(=O)NC4=NC=C(Cl)C=C4)C(=O)N(C)C",0.844,6,3,6]
["S4431","Ertugliflozin L-pyroglutamic acid","h7","L1300-32","in 10mM DMSO","FDA, DMF, EMA, NDC",null,"209806","Endocrinology/Metabolic Disease","SGLT","Apoptosis","Ertugliflozin (MK-8835, PF-04971729) L-pyroglutamic acid is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2) with IC50 of 0.877 nM for h-SGLT2. Ertugliflozin has the potential for the treatment of type 2 diabetes mellitus.",566,"1210344-83-4",100,176.68,10,17.67,"http://www.selleckchem.com/products/ertugliflozin-l-pyroglutamic-acid.html","C27H32ClNO10","Free Base","MK-8835 L-pyroglutamic acid, PF-04971729 L-pyroglutamic acid","CCOC1=CC=C(CC2=C(Cl)C=CC(=C2)C34OCC(CO)(O3)C(O)C(O)C4O)C=C1.OC(=O)C5CCC(=O)N5",1.349,5,5,7]
["S4432","Ixazomib Citrate (MLN9708)","a8","L1300-32","in 10mM DMSO","FDA, DMF, EMA, NDC, PMDA",null,"208462","Cancer","Proteasome","Proteases","Ixazomib citrate (MLN9708, Ninlaro) is a prodrug of Ixazomib (MLN2238), which is a selective, orally bioavailable inhibitor of 20S proteasome that inhibits the chymotrypsin-like proteolytic (β5) site with IC50 of 3.4 nM and Ki of 0.93 nM, respectively. Ixazomib (MLN2238) also inhibits caspase-like (β1) and trypsin-like (β2) proteolytic sites with IC50 of 31 nM and 3500 nM, respectively.",517.12,"1239908-20-3",100,193.38,"<1",0,"http://www.selleckchem.com/products/ixazomib-citrate.html","C20H23BCl2N2O9","Free Base","Ninlaro","CC(C)CC(NC(=O)CNC(=O)C1=C(Cl)C=CC(=C1)Cl)B2OC(=O)C(CC(O)=O)(CC(O)=O)O2",3.497,7,2,11]
["S4433","Eliglustat hemitartrate","b8","L1300-32","in 10mM DMSO","FDA, DMF, EMA, NDC, PMDA",null,"205494","Metabolic Disease","Glucosylceramide Synthase","Metabolism","Eliglustat hemitartrate (Genz-112638, Eliglustat tartrate) is a potent, specific and orally active inhibitor of glucosylceramide synthase with IC50 of 24 nM.",959.17,"928659-70-5",100,104.26,100,104.26,"http://www.selleckchem.com/products/eliglustat-hemitartrate.html","C50H78N4O14","Hemitartrate","Genz-112638, Eliglustat tartrate, Cerdelga","CCCCCCCC(=O)NC(CN1CCCC1)C(O)C2=CC3=C(OCCO3)C=C2.CCCCCCCC(=O)NC(CN4CCCC4)C(O)C5=CC6=C(OCCO6)C=C5.OC(C(O)C(O)=O)C(O)=O",-0.116,8,6,25]
["S4434","Ledipasvir acetone","c8","L1300-32","in 10mM DMSO","FDA, DMF, EMA, NDC",null,"205834","Infection","HCV","Microbiology","Ledipasvir (GS-5885) acetone is the active ingredient of Ledipasvir. Ledipasvir is a potent, oral active inhibitor of the hepatitis C virus (HCV) NS5A with EC50 of 31 pM and 4 pM against GT1a and GT1b replicon, respectively.",947.08,"1441674-54-9",100,105.59,"<1",0,"http://www.selleckchem.com/products/ledipasvir-acetone.html","C52H60F2N8O7","Free Base","GS-5885 acetone","COC(=O)NC(C(C)C)C(=O)N1CC2(CC2)CC1C3=NC=C([NH]3)C4=CC5=C(C=C4)C6=C(C=C(C=C6)C7=CC8=C(C=C7)N=C([NH]8)C9C%10CCC(C%10)N9C(=O)C(NC(=O)OC)C(C)C)C5(F)F.CC(C)=O",7.075,9,4,12]
["S4435","Metamizole sodium hydrate","d8","L1300-32","in 10mM DMSO","CFDA, PMDA","EP8.8, JP17",null,"Neurological Disease","COX","Immunology & Inflammation","Metamizole (Dipyrone) sodium hydrate is a potent inhitior of cyclooxygenase (COX) with strong analgesic as well as antipyretic and spasmolytic properties.",351.35,"5907-38-0",70,199.23,70,199.23,"http://www.selleckchem.com/products/metamizole-sodium-hydrate.html","C13H18N3NaO5S","Sodium hydrate","Dipyrone sodium hydrate","O.[Na+].CN(C[S]([O-])(=O)=O)C1=C(C)N(C)N(C1=O)C2=CC=CC=C2",-2.076,1,0,4]
["S4436","Pleuromutilin","e8","L1300-32","in 10mM DMSO","DMF",null,null,"Infection","Antibiotics,Bacterial","Microbiology","Pleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.",378.5,"125-65-5",76,200.79,"<1",0,"http://www.selleckchem.com/products/pleuromutilin.html","C22H34O5","Free Base","Drosophilin B, Mutilin 14-glycolate","CC1CCC23CCC(=O)C2C1(C)C(CC(C)(C=C)C(O)C3C)OC(=O)CO",2.372,3,2,4]
["S4438","Benzophenone","f8","L1300-32","in 10mM DMSO","DMF, NDC","USP36-NF31, IP2010",null,"Others","Others","Others","Benzophenone (Diphenyl ketone, Benzoylbenzene) filters out both UVA and UVB rays and is widely used in a great variety of sunscreens and personal care products.",182.22,"119-61-9",36,197.56,"<1",0,"http://www.selleckchem.com/products/benzophenone.html","C13H10O","Free Base","Diphenyl ketone, Benzoylbenzene","O=C(C1=CC=CC=C1)C2=CC=CC=C2",3.234,1,0,2]
["S4439","Almitrine mesylate","g8","L1300-32","in 10mM DMSO","DMF, CFDA",null,null,"Immunology/Inflammation/Respiratory Disease","Potassium Channel","Transmembrane Transporters","Almitrine mesylate (Almitrine bismesylate, Almitrine dimethanesulfonate, Almitrine dimesylate), a pharmacologically unique respiratory stimulant, acts as an agonist of peripheral chemoreceptors located on the carotid bodies. Almitrine mesylate inhibits the activity of Ca2+-dependent K+ channel by decreasing its open probability with IC50 of 0.22 μM.",669.76,"29608-49-9",100,149.31,"<1",0,"http://www.selleckchem.com/products/almitrine-mesylate.html","C28H37F2N7O6S2","Mesylate","Almitrine bismesylate, Almitrine dimethanesulfonate, Almitrine dimesylate","C[S](O)(=O)=O.C[S](O)(=O)=O.FC1=CC=C(C=C1)C(N2CCN(CC2)C3=NC(=NC(=N3)NCC=C)NCC=C)C4=CC=C(F)C=C4",5.258,3,2,10]
["S4440","2-Phenylacetamide","h8","L1300-32","in 10mM DMSO",null,"USP43-NF38",null,"Others","Estrogen/progestogen Receptor,GPR","Endocrinology & Hormones","2-Phenylacetamide, the main compound isolated from the seeds of Lepidium apetalum Willd (LA) with estrogenic activities, increases the expression of Estrogen receptorα (ERα), ERβ and GPR30 in the uterus and MCF-7 cells.",135.16,"103-81-1",27,199.76,27,199.76,"http://www.selleckchem.com/products/2-phenylacetamide.html","C8H9NO","Free Base","N/A","NC(=O)CC1=CC=CC=C1",0.866,1,1,2]
["S4441","Isomalt","a9","L1300-32","in 10mM DMSO","DMF","EP10.4, USP43-NF38, JP17",null,"Others","LDH","Metabolism","Isomalt (Palatinitol) is a sugar alcohol used as an excipient in commercially available solid oral dosage forms. Isomalt stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying.",344.31,"64519-82-0",69,200.4,69,200.4,"http://www.selleckchem.com/products/isomalt.html","C12H24O11","Free Base","Palatinitol","OCC(O)C(O)C(O)C(O)COC1OC(CO)C(O)C(O)C1O",-4.688,2,9,8]
["S4442","Neotame","b9","L1300-32","in 10mM DMSO",null,"USP43-NF38, IP2010",null,"Others","Others","Others","Neotame is a low-caloric and high-intensity artificial sweetener that reduces the alpha-diversity and altered the beta-diversity of the gut microbiome.",378.46,"165450-17-9",76,200.81,76,200.81,"http://www.selleckchem.com/products/neotame.html","C20H30N2O5","Free Base","N/A","COC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC(O)=O)NCCC(C)(C)C",-0.462,4,2,12]
["S4446","Dimercaprol","c9","L1300-32","in 10mM DMSO","FDA, CFDA, NDC, PMDA","EP10.4, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP17, IP2010","005939","Others","HIV","Microbiology","Dimercaprol (Bal, 2,3-Dimercapto-1-propanol, Dithioglycerol) is an acrolein scavenger that inhibits HIV-1 tat activity, viral production, and infectivity in vitro.",124.22,"59-52-9","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/dimercaprol.html","C3H8OS2","Free Base","Bal, 2,3-Dimercapto-1-propanol, Dithioglycerol","OCC(S)CS",0.534,0,1,2]
["S4447","Pipobroman","d9","L1300-32","in 10mM DMSO","FDA",null,"016245","Cancer/Hematology","DNA alkylator","DNA Damage/DNA Repair","Pipobroman (PB, Vercyte), a neutral amide of piperazine, acts as an alkylating agent with antiproliferative activity.",356.05,"54-91-1",71,199.41,"<1",0,"http://www.selleckchem.com/products/pipobroman.html","C10H16Br2N2O2","Free Base","PB, Vercyte","BrCCC(=O)N1CCN(CC1)C(=O)CCBr",0.647,2,0,4]
["S4481","Guanabenz","e9","L1300-32","in 10mM DMSO","FDA, DMF, CFDA","USP43-NF38, JP17","074025","Cardiovascular Disease","Adrenergic Receptor","Endocrinology & Hormones","Guanabenz (GBZ, GA, Wytensin, Wy-8678,BR-750) is an orally active central alpha 2-adrenoceptor (α2 adrenergic receptor) agonist with antihypertensive action.",231.08,"5051-62-7",12,51.93,"<1",0,"http://www.selleckchem.com/products/guanabenz.html","C8H8Cl2N4","Free Base","GBZ, GA, Wytensin, Wy-8678,BR-750","NC(=N)N\\N=C\\C1=C(Cl)C=CC=C1Cl",2.192,1,2,3]
["S4483","Iproniazid phosphate","f9","L1300-32","in 10mM DMSO","approved for use in France",null,null,"Infection/Neurological Disease","MAO","Neuronal Signaling","Iproniazid (Marsilid, Iprazid) phosphate is a non-selective, irreversible monoamine oxidase (MAO) inhibitor (MAOI) that is used as an antidepressive agent.",277.21,"305-33-9",55,198.41,55,198.41,"http://www.selleckchem.com/products/iproniazid-phosphate.html","C9H16N3O5P","Phosphate","N/A","CC(C)NNC(=O)C1=CC=NC=C1.O[P](O)(O)=O",-0.347,2,2,3]
["S4484","Trametinib DMSO solvate","g9","L1300-32","in 10mM DMSO","FDA, DMF, EMA, NDC, PMDA",null,"204114","Cancer","Apoptosis related,Autophagy,MEK","MAPK","Trametinib (GSK1120212, JTP-74057, Mekinist) DMSO solvate is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assay. Trametinib activates autophagy and induces apoptosis.",693.53,"1187431-43-1",50,72.09,"<1",0,"http://www.selleckchem.com/products/trametinib-dmso-solvate.html","C28H29FIN5O5S","Free Base","GSK1120212, JTP-74057, Mekinist","CN1C(=O)C(=C2N(C(=O)N(C3CC3)C(=O)C2=C1NC4=C(F)C=C(I)C=C4)C5=CC=CC(=C5)NC(C)=O)C.C[S](C)=O",2.86,5,2,5]
["S4486","Thiamine monochloride","h9","L1300-32","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38,KP Ⅹ, EP9.0, Ph.Int_6th, JP16, IP2010","006071","Metabolic Disease","Vitamin","Metabolism","Thiamine (Vitamin B1) monochloride is an essential vitamin that plays an important role in cellular production of energy from ingested food and enhances normal neuronal actives.",300.81,"59-43-8",60,199.46,60,199.46,"http://www.selleckchem.com/products/thiamine-monochloride.html","C12H17ClN4OS","Monochloride","Vitamin B1","[Cl-].CC1=NC=C(C[N+]2=CSC(=C2C)CCO)C(=N1)N",-1.626,2,2,4]
["S4488","Delafloxacin Meglumine","a10","L1300-32","in 10mM DMSO","FDA, EMA, NDC",null,"208610","Infection","Antibiotics","Immunology & Inflammation","Delafloxacin (ABT-492, RX-3341, WQ-3034, Baxdela) meglumine is a broad-spectrum fluoroquinolone antibiotic against multiple pathogens.",635.97,"352458-37-8",100,157.24,100,157.24,"http://www.selleckchem.com/products/delafloxacin-meglumine.html","C25H29ClF3N5O9","Free Base","ABT-492, RX-3341, WQ-3034, Baxdela","CNCC(O)C(O)C(O)C(O)CO.NC1=NC(=C(F)C=C1F)N2C=C(C(O)=O)C(=O)C3=CC(=C(N4CC(O)C4)C(=C23)Cl)F",-2.821,3,8,9]
["S4489","Tetraethylammonium chloride","b10","L1300-32","in 10mM DMSO","DMF","EP10.5, USP43-NF38",null,"Others","Potassium Channel","Transmembrane Transporters","Tetraethylammonium (TEA) chloride is a nonspecific potassium channel blocker with antitumor properties.",165.7,"56-34-8",33,199.16,33,199.16,"http://www.selleckchem.com/products/tetraethylammonium-chloride.html","C8H20ClN","Free Base","TEA chloride","[Cl-].CC[N+](CC)(CC)CC",-2.314,0,0,4]
["S4490","Tetracycline","c10","L1300-32","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, JP17, Ph.Int_6th, IP2010","060059","Infection","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Bacterial","Microbiology","Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites.",444.43,"60-54-8",89,200.26,"<1",0,"http://www.selleckchem.com/products/tetracycline.html","C22H24N2O8","Free Base","TC","CN(C)C1C2CC3C(=C(O)C4=C(C=CC=C4O)C3(C)O)C(=O)C2(O)C(=C(C(N)=O)C1=O)O",-1.011,3,4,2]
["S4491","Cetylpyridinium chloride monohydrate","d10","L1300-32","in 10mM DMSO","DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38",null,"Infection","Influenza Virus","Microbiology","Cetylpyridinium chloride (CPC, Hexadecylpyridinium chloride) monohydrate is a broad-spectrum antimicrobial agent that possesses virucidal activity against susceptible and resistant strains of influenza virus by targeting and disrupting the viral envelope.",358,"6004-24-6",72,201.12,72,201.12,"http://www.selleckchem.com/products/cetylpyridinium-chloride-monohydrate.html","C21H40ClNO","Monohydrate","CPC monohydrate, Hexadecylpyridinium chloride monohydrate","O.[Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1",5.356,0,0,15]
["S4493","Sodium nitroprusside","e10","L1300-32","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP9.2, Ph.Int_6th, USP40-NF35, IP2010","018581","Cardiovascular Disease","Others","Others","Sodium nitroprusside (SNP, Ro 21-2498) is a generically available and rapid-acting intravenous (IV) vasodilator that dilates cerebral vessels and increases internal carotid (ICA) flow.",261.92,"14402-89-2",52,198.53,52,198.53,"http://www.selleckchem.com/products/sodium-nitroprusside.html","C5FeN6O2Na","Sodium","SNP, Ro 21-2498","[Na+].[Na+].[Fe++](|[C-]#N)(|[C-]#N)(|[C-]#N)(|[C-]#N)(|[C-]#N)|N#[O+]",0.204,0,1,0]
["S4495","Quinine","f10","L1300-32","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP17, IP2010","091661","Parasite","Potassium Channel","Transmembrane Transporters","Quinine, an alkaloid derived from the bark of the cinchona tree, is an anti-malaria agent and a potassium channel inhibitor that inhibits mSlo3 (KCa 5.1) channel currents evoked by voltage pulses to +100 mV with IC50 of 169 μM.",324.42,"130-95-0",65,200.36,"<1",0,"http://www.selleckchem.com/products/quinine.html","C20H24N2O2","Free Base","N/A","COC1=CC2=C(C=CN=C2C=C1)C(O)C3CC4CCN3CC4C=C",2.733,2,1,4]
["S4496","Maltose monohydrate","g10","L1300-32","in 10mM DMSO","DMF, PMDA","EP10.5, USP43-NF38, KP Ⅹ, JP17",null,"Others","Others","Others","Maltose (Maltobiose, Malt Sugar, Beta-Maltose, D-Maltose) monohydrate, an non-essential nutrient that provides energy, is an intermediate in the intestinal digestion of glycogen and starch, and is found in germinating grains (and other plants and vegetables).",360.31,"6363-53-7",72,199.83,72,199.83,"http://www.selleckchem.com/products/maltose-monohydrate.html","C12H24O12","Monohydrate","Maltobiose, Malt Sugar, Beta-Maltose, D-Maltose","O.OCC(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)C(O)C=O",-4.745,3,8,8]
["S4531","Iohexol","h10","L1300-32","in 10mM DMSO","FDA, DMF, CFDA, OMDA","EP10.5, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP17","018956","Diagnosis","Others","Others","Iohexol (Omnipaque) is a radiographic contrast agent that can be used as an exogenous filtration marker for accurate glomerular filtration rate (GFR) estimates.",821.14,"66108-95-0",100,121.78,100,121.78,"http://www.selleckchem.com/products/iohexol.html","C19H26I3N3O9","Free Base","Omnipaque","CC(=O)N(CC(O)CO)C1=C(I)C(=C(I)C(=C1I)C(=O)NCC(O)CO)C(=O)NCC(O)CO",-1.844,3,8,12]
["S4572","Homosalate","a11","L1300-32","in 10mM DMSO","NDC","USP43-NF38",null,"Others","Akt,PI3K","PI3K/Akt/mTOR","Homosalate (HMS, Homomenthyl salicylate) is an organic ultraviolet filter used in most sunscreens but has been reported to be toxic to marine organisms. Homosalate aggravates the invasion of human trophoblast cells as well as regulates intracellular signaling pathways including PI3K/AKT and MAPK pathways.",262.34,"118-56-9","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/homosalate.html","C16H22O3","Free Base","HMS, Homomenthyl salicylate","CC1CC(CC(C)(C)C1)OC(=O)C2=C(O)C=CC=C2",4.011,2,1,3]
["S4681","Quinidine hydrochloride monohydrate","b11","L1300-32","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP17, IP2010","084932","Cardiovascular Disease","Potassium Channel","Transmembrane Transporters","Quinidine hydrochloride monohydrate is an anti-arrythmic agent and a potent potassium channel inhibitor with IC50 of 19.9 μM.",378.89,"6151-40-2",76,200.59,10,26.39,"http://www.selleckchem.com/products/quinidine-hydrochloride-monohydrate.html","C20H27ClN2O3","Hydrochloride monohydrate","N/A","O.Cl.COC1=CC2=C(C=CN=C2C=C1)C(O)C3CC4CCN3CC4C=C",2.908,2,1,4]
["S4713","Atropine","c11","L1300-32","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP17, IP2010","071295","Others","AChR","Neuronal Signaling","Atropine (Atropen, Atnaa, Tropine tropate, DL-Hyoscyamine) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with anti-myopia effect.",289.37,"51-55-8",58,200.44,"<1",0,"http://www.selleckchem.com/products/atropine.html","C17H23NO3","Free Base","N/A","CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",1.721,2,1,5]
["S4730","Pyrithioxin Dihydrochloride","d11","L1300-32","in 10mM DMSO","CFDA",null,null,"Neurological Disease","Others","Others","Pyrithioxin (Bonifen, Encefabol, Pyritinol, Vitamin B6 disulfide) Dihydrochloride is a neurotropic agent which reduces permeability of blood-brain barrier to phosphate with no vitamin B6 activity.",441.39,"10049-83-9",88,199.37,88,199.37,"http://www.selleckchem.com/products/pyrithioxin-dihydrochloride.html","C16H22Cl2N2O4S2","Dihydrochloride","Bonifen Dihydrochloride, Encefabol Dihydrochloride, Pyritinol Dihydrochloride, Vitamin B6 disulfide Dihydrochloride","Cl.Cl.CC1=NC=C(CSSCC2=CN=C(C)C(=C2CO)O)C(=C1O)CO",1.887,2,4,7]
["S4842","Balsalazide","e11","L1300-32","in 10mM DMSO","FDA, DMF, CFDA, NDC","USP43-NF38","077806","Gastroenterology","Immunology & Inflammation related,Interleukins,STAT","Immunology & Inflammation","Balsalazide (Colazal, Giazo), an aminosalicylate and oral prodrug, is enzymatically cleaved in the colon to produce the anti-inflammatory agent mesalazine. Balsalazide suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway.",357.32,"80573-04-2",71,198.7,71,198.7,"http://www.selleckchem.com/products/balsalazide.html","C17H15N3O6","Free Base","Colazal, Giazo","OC(=O)CCNC(=O)C1=CC=C(C=C1)N=NC2=CC(=C(O)C=C2)C(O)=O",2.524,5,2,7]
["S4895","Nilotinib hydrochloride monohydrate","f11","L1300-32","in 10mM DMSO","FDA, DMF, EMA, NDC, PMDA","EP10.5","022068","Cancer","AMPK,Autophagy,Bcr-Abl","Angiogenesis","Nilotinib (AMN-107, Tasigna) hydrochloride monohydrate is a selective and orally bioavailable inhibitor of Bcr-Abl with IC50 < 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.",583.99,"923288-90-8",100,171.24,"<1",0,"http://www.selleckchem.com/products/nilotinib-hydrochloride-monohydrate.html","C28H25ClF3N7O2","Hydrochloride monohydrate","Tasigna, AMN-107 hydrochloride monohydrate","O.Cl.CC1=C[N](C=N1)C2=CC(=CC(=C2)NC(=O)C3=CC(=C(C)C=C3)NC4=NC=CC(=N4)C5=CN=CC=C5)C(F)(F)F",5.259,5,2,7]
["S4929","Enasidenib Mesylate","g11","L1300-32","in 10mM DMSO","FDA, NDC",null,"209606","Cancer","Dehydrogenase","Metabolism","Enasidenib (Idhifa, AG-221) mesylate is an orally available, selective and potent inhibitor of mutant isocitrate dehydrogenase 2 (IDH2).",569.48,"1650550-25-6",100,175.6,"<1",0,"http://www.selleckchem.com/products/enasidenib-mesylate.html","C20H21F6N7O4S","Mesylate","Idhifa, AG-221 mesylate","CC(C)(O)CNC1=NC(=NC(=N1)C2=NC(=CC=C2)C(F)(F)F)NC3=CC(=NC=C3)C(F)(F)F.C[S](O)(=O)=O",4.464,5,2,8]
["S4944","Fostamatinib disodium hexahydrate","h11","L1300-32","in 10mM DMSO","FDA, EMA, NDC",null,"209299","Hematology/Immunology","Syk","Angiogenesis","Fostamatinib (R788) disodium (Tamatinib Fosdium) hexahydrate, a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM in a cell-free assay.",732.51,"914295-16-2",100,136.52,"<1",0,"http://www.selleckchem.com/products/fostamatinib-disodium-hexahydrate.html","C23H36FN6Na2O15P","Disodium hexahydrate","Tavalisse, R788 disodium hexahydrate, Tamatinib Fosdium hexahydrate","O.O.O.O.O.O.[Na+].[Na+].COC1=CC(=CC(=C1OC)OC)NC2=NC=C(F)C(=N2)NC3=NC4=C(OC(C)(C)C(=O)N4CO[P]([O-])([O-])=O)C=C3",0.038,9,2,10]
["S4945","Ethacridine lactate","a2","L1300-33","in 10mM DMSO","DMF, CFDA","EP10.5",null,"Infection","Anti-infection,PARG","Immunology & Inflammation","Ethacridine lactate (Acrinol) is an aromatic organic compound based on acridine used as an antiseptic agent. Ethacridine lactate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.",343.38,"1837-57-6",69,200.94,69,200.94,"http://www.selleckchem.com/products/ethacridine-lactate.html","C18H21N3O4","Free Base","Acrinol","CCOC1=CC2=C(N)C3=C(C=C(N)C=C3)N=C2C=C1.CC(O)C(O)=O",1.8,3,3,3]
["S4947","Regorafenib Hydrochloride","b2","L1300-33","in 10mM DMSO","FDA, DMF, EMA, NDC, PMDA","EP10.5","203085","Cancer","c-Kit,c-RET,PDGFR,Raf,VEGFR","Protein Tyrosine Kinase","Regorafenib (Stivarga, BAY 73-4506) Hydrochloride is a multi-target inhibitor for VEGFR1, Murine VEGFR2/3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM, 4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.",519.28,"835621-07-3",100,192.57,"<1",0,"http://www.selleckchem.com/products/regorafenib-hydrochloride.html","C21H16Cl2F4N4O3","Hydrochloride","Stivarga, BAY 73-4506 hydrochloride","Cl.CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(NC(=O)NC3=CC(=C(Cl)C=C3)C(F)(F)F)C=C2)F",4.763,4,3,6]
["S4948","Rucaparib","c2","L1300-33","in 10mM DMSO","FDA, DMF, EMA, NDC",null,"209115","Cancer","PARP","DNA Damage/DNA Repair","Rucaparib (Rubraca, AG014699, PF01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains.",323.36,"283173-50-2",65,201.01,"<1",0,"http://www.selleckchem.com/products/rucaparib.html","C19H18FN3O","Free Base","Rubraca, AG014699, PF01367338","CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=C3C(=CC(=C4)F)[NH]2",2.959,1,3,3]
["S4967","Ceritinib dihydrochloride","d2","L1300-33","in 10mM DMSO","FDA, DMF, EMA, NDC, PMDA",null,"205755","Cancer","ALK,IGF-1R,Serine/threonin kinase","Protein Tyrosine Kinase","Ceritinib (Zykadia, LDK378) dihydrochloride is a selective, orally bioavailable and ATP-competitive inhibitor of ALK with IC50 of 0.2 nM. Ceritinib dihydrochloride also inhibits InsR, IGF-1R and STK22D with IC50 of 7 nM, 8 nM and 23 nM, respectively. Ceritinib exhibits antitomor activity.",631.06,"1380575-43-8",13,20.6,"<1",0,"http://www.selleckchem.com/products/ceritinib-dihydrochloride.html","C28H38Cl3N5O3S","Dihydrochloride","Zykadia, LDK378 dihydrochloride","Cl.Cl.CC(C)OC1=C(NC2=NC=C(Cl)C(=N2)NC3=CC=CC=C3[S](=O)(=O)C(C)C)C=C(C)C(=C1)C4CCNCC4",7.243,5,3,9]
["S4974","Oxacillin sodium","e2","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC","EP10.5, USP43-NF38","050195","Infection","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics","Microbiology","Oxacillin sodium (salt) is a narrow-spectrum β-lactam antibiotic that can be used for treatment of methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia.",423.42,"1173-88-2",85,200.75,85,200.75,"http://www.selleckchem.com/products/oxacillin-sodium.html","C19H18N3NaO5S","Sodium","Oxacillin sodium salt","[Na+].CC1=C(C(=O)NC2C3SC(C)(C)C(N3C2=O)C([O-])=O)C(=NO1)C4=CC=CC=C4",0.161,4,1,4]
["S4979","Procaine penicillin G","f2","L1300-33","in 10mM DMSO","FDA, CFDA, NDC","USP43-NF38, EP9.0, Ph.Int_6th","060099","Infection","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics","Microbiology","Penicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R), a crystalline complex combining penicillin G with procaine, is a β-lactam antibiotic.",570.7,"54-35-3",100,175.22,10,17.52,"http://www.selleckchem.com/products/procaine-penicillin-g.html","C29H38N4O6S","Free Base","PGP, Penicillin G Procaine, Bicillin C-R","CCN(CC)CCOC(=O)C1=CC=C(N)C=C1.CC2(C)SC3C(NC(=O)CC4=CC=CC=C4)C(=O)N3C2C(O)=O",-0.136,5,2,11]
["S5008","Ciprofloxacin hydrochloride","g2","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC","EP10.5, USP43-NF38, KP Ⅹ, JP17, Ph.Int_5th , IP2010","074124","Infection","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Bacterial,Topoisomerase","Microbiology","Ciprofloxacin (CPX, Cetraxal, Ciloxan, Cipro, Bay-09867) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases).",367.8,"93107-08-5",7,19.03,74,201.2,"http://www.selleckchem.com/products/ciprofloxacin-hydrochloride.html","C17H19ClFN3O3","Hydrochloride","CPX, Cetraxal, Ciloxan, Cipro, Bay-09867 hydrochloride","Cl.OC(=O)C1=CN(C2CC2)C3=CC(=C(F)C=C3C1=O)N4CCNCC4",-0.888,2,1,3]
["S5026","Irinotecan hydrochloride","h2","L1300-33","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","EP10.5, USP43-NF38, IP2010","077219","Cancer","Topoisomerase","DNA Damage/DNA Repair","Irinotecan (CPT-11, (+)-Irinotecan) hydrochloride is an inhibitor of Topoisomerase I (Topo I) that exhibits cytotoxicity in LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively.",623.14,"100286-90-6",100,160.48,"<1",0,"http://www.selleckchem.com/products/irinotecan-hydrochloride.html","C33H39ClN4O6","Hydrochloride","CPT-11 hydrochloride, (+)-Irinotecan hydrochloride","Cl.CCC1=C2CN3C(=O)C4=C(C=C3C2=NC5=C1C=C(OC(=O)N6CCC(CC6)N7CCCCC7)C=C5)C(O)(CC)C(=O)OC4",4.068,6,0,5]
["S5080","Neticonazole","a3","L1300-33","in 10mM DMSO","PMDA",null,null,"Infection","Fungal","Microbiology","Neticonazole (SS717) is a selecvie inhibitor of exosome biogenesis and secretion. Neticonazole exhibits Neticonazole antifungal and antitumor activity.",302.43,"130726-68-0",60,198.39,60,198.39,"http://www.selleckchem.com/products/neticonazole.html","C17H22N2OS","Free Base","SS717","CCCCCOC1=CC=CC=C1C(=C\\SC)/[N]2C=CN=C2",3.456,2,0,8]
["S5181","Levobupivacaine","b3","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, PMDA",null,"020997","Neurological Disease","Sodium Channel","Transmembrane Transporters","Levobupivacaine (Chirocaine, (S)-(-)-Bupivacaine, L-(-)-Bupivacaine), the S (-)-enantiomer of bupivacaine, is a long-acting amide local anaesthetic used in analgesia and anaesthesia. Levobupivacaine exhibits effects on motor and sensory nerves by inhibiting the opening of voltage-gated sodium channels.",288.43,"27262-47-1",58,201.09,"<1",0,"http://www.selleckchem.com/products/levobupivacaine.html","C18H28N2O","Free Base","Chirocaine, (S)-(-)-Bupivacaine, L-(-)-Bupivacaine","CCCCN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",4.31,1,1,5]
["S5184","Dexamethasone palmitate","c3","L1300-33","in 10mM DMSO","CFDA, PMDA",null,null,"Cancer/Infection","Anti-infection,Glucocorticoid Receptor","Endocrinology & Hormones","Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone (DXM), is a glucocorticoid receptor agonist with a 47-fold lower affinity for the glucocorticoid receptor than DXM. Dexamethasone palmitate (DXP) exhibits anti-inflammatory activity.",630.87,"14899-36-6",100,158.51,"<1",0,"http://www.selleckchem.com/products/dexamethasone-palmitate.html","C38H59FO6","Free Base","DXP","CCCCCCCCCCCCCCCC(=O)OCC(=O)C1(O)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C",8.684,4,1,18]
["S5185","Perospirone","d3","L1300-33","in 10mM DMSO","CFDA, PMDA",null,null,"Neurological Disease","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Perospirone (SM-9018 free base) is an orally active antagonist of 5-hydroxytryptamine2 (5-HT2) receptor, dopamine2 (D2) receptor and 5-HT1A receptor with Ki of 0.6 nM, 1.4 nM and 2.9 nM, respectively.",426.57,"150915-41-6",85,199.26,"<1",0,"http://www.selleckchem.com/products/perospirone.html","C23H30N4O2S","Free Base","SM-9018 free base","O=C1C2CCCCC2C(=O)N1CCCCN3CCN(CC3)C4=NSC5=CC=CC=C45",4.041,3,0,6]
["S5186","Cefpiramide","e3","L1300-33","in 10mM DMSO","DMF,CFDA,FDA",null,null,"Infection","Antineoplastic and Immunosuppressive Antibiotics,Bacterial","Microbiology","Cefpiramide (Cefpiramide acid, Cefpiramido, Cefpiramidum, WY-44635, SM-1652) is a pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.",612.64,"70797-11-4",100,163.23,"<1",0,"http://www.selleckchem.com/products/cefpiramide.html","C25H24N8O7S2","Free Base","Cefpiramide acid, Cefpiramido, Cefpiramidum, WY-44635, SM-1652","C[N]1N=NN=C1SCC2=C(N3C(SC2)C(NC(=O)C(NC(=O)C4=CNC(=CC4=O)C)C5=CC=C(O)C=C5)C3=O)C(O)=O",-0.848,8,4,9]
["S5187","Ribociclib hydrochloride","f3","L1300-33","in 10mM DMSO","FDA, DMF, EMA, NDC",null,"209092","Cancer","CDK","Cell Cycle","Ribociclib (LEE011) hydrochloride is a highly specific dual inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM, respectively.",471,"1211443-80-9",94,199.58,94,199.58,"http://www.selleckchem.com/products/ribociclib-hydrochloride.html","C23H31ClN8O","Hydrochloride","LEE011 hydrochloride","Cl.CN(C)C(=O)C1=CC2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2[N]1C5CCCC5",3.282,4,2,5]
["S5188","Ribociclib succinate","g3","L1300-33","in 10mM DMSO","FDA, DMF, EMA, NDC",null,"209092","Cancer","CDK","Cell Cycle","Ribociclib (LEE011) succinate (Kisqali) is a highly specific dual inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM, respectively.",552.63,"1374639-75-4",100,180.95,"<1",0,"http://www.selleckchem.com/products/ribociclib-succinate.html","C27H36N8O5","Succinate","LEE011 succinate, Kisqali","CN(C)C(=O)C1=CC2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2[N]1C5CCCC5.OC(=O)CCC(O)=O",-0.164,6,2,8]
["S5189","Lesinurad sodium","h3","L1300-33","in 10mM DMSO","FDA, DMF, EMA,",null,"209203","Metabolic Disease","OAT","Transmembrane Transporters","Lesinurad (Selexipag, RDEA-594) sodium (Zurampic) is a selective uric acid reabsorption inhibitor (SURI) under investigation for treatment of gout. Lesinurad sodium inhibits the uric acid transporter URAT1 and Kidney transporter OAT with IC50/Km of 4.3 μM/0.85 μM and 3.5 μM/2 μM for OAT1 and OAT3, respectively.",426.26,"1151516-14-1",85,199.41,8,18.77,"http://www.selleckchem.com/products/lesinurad-sodium.html","C17H13BrN3NaO2S","Sodium","Selexipag, Zurampic, RDEA-594 sodium","[Na+].[O-]C(=O)CSC1=NN=C(Br)[N]1C2=CC=C(C3CC3)C4=CC=CC=C24",2.783,2,0,5]
["S5190","Crizotinib hydrochloride","a4","L1300-33","in 10mM DMSO","FDA, EMA, NDC, PMDA",null,"202570","Cancer","ALK,Autophagy,c-Met,ROS1","Protein Tyrosine Kinase","Crizotinib (PF-02341066) hydrochloride (Xalkori) inhibits tyrosine phosphorylation of c-Met and nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) with IC50 of of 11 nM and 24 nM in cell-based assays, respectively. Crizotinib hydrochloride is also a potent ROS1 inhibitor with Ki less than 0.025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines.",486.8,"1415560-69-8",97,199.26,97,199.26,"http://www.selleckchem.com/products/crizotinib-hydrochloride.html","C21H23Cl3FN5O","Hydrochloride","Xalkori, PF-02341066 hydrochloride","Cl.CC(OC1=C(N)N=CC(=C1)C2=C[N](N=C2)C3CCNCC3)C4=C(Cl)C=CC(=C4Cl)F",4.075,3,2,5]
["S5191","Cinacalcet","b4","L1300-33","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA",null,"090476","Endocrinology","Calcium Channel","Transmembrane Transporters","Cinacalcet (AMG073, Sensipar, Cin) is an orally active, allosteric agonist of receptors for calcium (CaR) that increases the sensitivity of the CaR to Ca.",357.41,"226256-56-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/cinacalcet.html","C22H22F3N","Free Base","AMG073, Sensipar, Cin","CC(NCCCC1=CC(=CC=C1)C(F)(F)F)C2=CC=CC3=CC=CC=C23",5.956,0,1,7]
["S5192","S-(+)-Ketoprofen","c4","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, JP17, IP2010","020499","Neurological Disease","COX","Immunology & Inflammation","S-(+)-Ketoprofen (Compound 1, Actron, (S)-Ketoprofen, Dexketoprofen) is a potent inhibitor of cyclooxygenase (COX) with IC50 of 1.9 nM and 27 nM for COX-1 and COX-2, respectively.",254.28,"22161-81-5",51,200.57,"<1",0,"http://www.selleckchem.com/products/s-ketoprofen.html","C16H14O3","Free Base","Actron, (S)-Ketoprofen, Dexketoprofen","CC(C(O)=O)C1=CC(=CC=C1)C(=O)C2=CC=CC=C2",3.361,2,0,4]
["S5193","L-Thyroxine sodium salt pentahydrate","d4","L1300-33","in 10mM DMSO",null,"USP43-NF38, IP2010",null,"Metabolic Disease","THR","Metabolism","L-Thyroxine (Levothyroxine, L-T4) sodium salt pentahydrate is a synthetic T4 hormone used to counterbalance hypothyroidism.",888.93,"6106-07-6",100,112.49,"<1",0,"http://www.selleckchem.com/products/l-thyroxine-sodium-salt-pentahydrate.html","C15H20I4NNaO9","Sodium salt pentahydrate","Sodium Levothyroxine pentahydrate, L-T4 sodium pentahydrate","O.O.O.O.O.[Na+].NC(CC1=CC(=C(OC2=CC(=C(O)C(=C2)I)I)C(=C1)I)I)C([O-])=O",1.994,1,2,5]
["S5194","Furosemide sodium","e4","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, Ph.Int_6th, IP2010","018025","Cardiovascular Disease/Metabolic Disease","GABA Receptor,NKCC","Transmembrane Transporters","Furosemide (Frusemide) sodium is a potent and orally active inhibitor of Na-K-Cl cotransporter (NKCC). Furosemide sodium is a subtype-selective antagonist of gamma-aminobutyric acid type A (GABAA) receptor.",352.73,"41733-55-5",71,201.29,71,201.29,"http://www.selleckchem.com/products/furosemide-sodium.html","C12H10ClN2NaO5S","Sodium","Lasix, Frusemide Sodium","[Na+].N[S](=O)(=O)C1=C(Cl)C=C(NCC2=CC=CO2)C(=C1)C([O-])=O",-0.071,3,2,5]
["S5195","Rucaparib Camsylate","f4","L1300-33","in 10mM DMSO","FDA, DMF, EMA, NDC",null,"209115","Cancer","PARP","DNA Damage/DNA Repair","Rucaparib (Rubraca, AG014699, PF01367338) Camsylate is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains.",555.66,"1859053-21-6",100,179.97,"<1",0,"http://www.selleckchem.com/products/rucaparib-camsylate.html","C29H34FN3O5S","Camsylate","Rubraca, AG014699 Camsylate, PF01367338 Camsylate","CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=C3C(=CC(=C4)F)[NH]2.CC5(C)C6CCC5(C[S](O)(=O)=O)C(=O)C6",3.888,2,3,5]
["S5196","Promethazine","g4","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP16, IP2010","089013","Immunology","Histamine Receptor","Neuronal Signaling","Promethazine is a potent histamine H1 receptor antagonist. Promethazine is a medication used in the management and treatment of allergic conditions, nausea and vomiting, motion sickness, and sedation. Promethazine exhibits antiparasitic properties.",284.42,"60-87-7",29,101.96,"<1",0,"http://www.selleckchem.com/products/promethazine.html","C17H20N2S","Free Base","N/A","CC(CN1C2=CC=CC=C2SC3=CC=CC=C13)N(C)C",4.39,0,0,3]
["S5199","Oxytetracycline hydrochloride","h4","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, PMDA","EP10.5, USP43-NF38, KP Ⅹ, IP2010","060634","Infection","Antibiotics,Bacterial","Microbiology","Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.",496.89,"2058-46-0",99,199.24,99,199.24,"http://www.selleckchem.com/products/oxytetracycline-hydrochloride.html","C22H25ClN2O9","Hydrochloride","OTC, Oxycycin, Stevacin, Terramycin","Cl.CN(C)C1C2C(O)C3C(=C(O)C4=C(C=CC=C4O)C3(C)O)C(=O)C2(O)C(=C(C(N)=O)C1=O)O",-1.629,3,5,2]
["S5219","Allylestrenol","a5","L1300-33","in 10mM DMSO","CFDA, PMDA",null,null,"Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Allylestrenol is an orally active progestagen of the 19-nortestosterone series resembling progesterone.",300.48,"432-60-0",60,199.68,"<1",0,"http://www.selleckchem.com/products/allylestrenol.html","C21H32O","Free Base","N/A","CC12CCC3C(CCC4=CCCCC34)C1CCC2(O)CC=C",5.062,0,0,2]
["S5235","Cefodizime","b5","L1300-33","in 10mM DMSO","CFDA","KP Ⅹ, JP17",null,"Infection","Bacterial","Microbiology","Cefodizime (CEF, CDZ) is an aminothiazolyl cephalosporin with a broad spectrum of antibacterial activity.",584.67,"69739-16-8",100,171.04,"<1",0,"http://www.selleckchem.com/products/cefodizime.html","C20H20N6O7S4","Free Base","CEF, CDZ","CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)CSC3=NC(=C(CC(O)=O)S3)C)C4=CSC(=N4)N",0.677,8,2,10]
["S5300","Trometamol hydrochloride","c5","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38",null,"Metabolic Disease","Others","Others","Trometamol (THAM, Tromethamine, TRIS-HCL) hydrochloride, a proton acceptor, is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. Trometamol rapidly restores pH and acid-base regulation in acidaemia.",157.6,"1185-53-1",32,203.05,32,203.05,"http://www.selleckchem.com/products/trometamol-hydrochloride.html","C4H12ClNO3","Hydrochloride","THAM, Tromethamine hydrochloride, TRIS-HCL","Cl.NC(CO)(CO)CO",-1.999,0,4,3]
["S5417","Spectinomycin dihydrochloride pentahydrate","d5","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, PMDA","EP10.5, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP17, IP2010","050347","Infection","Antibiotics,Bacterial","Microbiology","Spectinomycin dihydrochloride pentahydrate (Trobicin) is a widely used antibiotic that inhibits bacterial protein synthesis by blocking translocation of messenger RNA and transfer RNAs on the ribosome.",495.35,"22189-32-8",99,199.86,99,199.86,"http://www.selleckchem.com/products/spectinomycin-dihydrochloride-pentahydrate.html","C14H36Cl2N2O12","Dihydrochloride pentahydrate","Trobicin, Spectinomycin hydrochloride hydrate","O.O.O.O.O.Cl.Cl.CNC1C(O)C(NC)C2OC3(O)C(OC(C)CC3=O)OC2C1O",-2.602,4,4,2]
["S5489","Prednisone acetate","e5","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC","EP10.5, USP43-NF38, IP2010","017109","Immunology","Glucocorticoid Receptor","Endocrinology & Hormones","Prednisone acetate (Betapar, Cortan, Deltasone, Fernisone, Meticorten, Prednisone 21-acetate) is a glucocorticoid steroid that can be used as a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties.",400.46,"125-10-0",27,67.42,"<1",0,"http://www.selleckchem.com/products/prednisone-acetate.html","C23H28O6","Free Base","Betapar, Cortan, Deltasone, Fernisone, Meticorten, Prednisone 21-acetate","CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)C=CC4(C)C3C(=O)CC12C",1.596,5,0,4]
["S5495","Ceftiofur sodium","f5","L1300-33","in 10mM DMSO",null,"USP43-NF38",null,"Infection","Bacterial","Microbiology","Ceftiofur sodium is a semisynthetic, beta-lactamase-stable, broad-spectrum cephalosporin with antibacterial activity.",545.54,"104010-37-9",100,183.3,100,183.3,"http://www.selleckchem.com/products/ceftiofur-sodium.html","C19H16N5NaO7S3","Sodium","N/A","[Na+].CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)CSC(=O)C3=CC=CO3)C4=CSC(=N4)N",-0.766,7,2,9]
["S5608","Pantoprazole sodium hydrate","g5","L1300-33","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC","EP10.5, USP43-NF38, IP2010","022226","Endocrinology/Gastrointestinal Disease/Inflammation","ATPase,Proton Pump","Transmembrane Transporters","Pantoprazole (BY10232, SKF96022) sodium hydrate (Protonix) is a potent inhibitor of H+/K(+)-ATPase with IC50 of 6.8 μM.",864.75,"164579-32-2",100,115.64,17,19.66,"http://www.selleckchem.com/products/pantoprazole-sodium-hydrate.html","C32H34F4N6Na2O11S2","Sodium hydrate","Protonix, BY1023 sodium hydrate, SKF96022 sodium hydrate","O.O.O.[Na+].[Na+].COC1=C(OC)C(=NC=C1)C[S](=O)C2=NC3=C([N-]2)C=CC(=C3)OC(F)F.COC4=C(OC)C(=NC=C4)C[S](=O)C5=NC6=C([N-]5)C=CC(=C6)OC(F)F",5.145,12,0,14]
["S5644","Ceftriaxone Sodium","h5","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.4, USP43-NF38, KP Ⅹ, JP17","090701","Infection","Antibiotics,Bacterial","Microbiology","Ceftriaxone Sodium is the sodium salt form of ceftriaxone, a beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity.",598.54,"74578-69-1",100,167.07,-1,0,"http://www.selleckchem.com/products/ceftriaxone-sodium.html","C18H16N8Na2O7S3","Sodium","N/A","[Na+].[Na+].CO/N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)CSC3=NC(=O)C(=NN3C)[O-])C4=CSC(=N4)N",-2.451,8,2,8]
["S5671","Amcinonide","a6","L1300-33","in 10mM DMSO","FDA, DMF, NDC, PMDA","USP43-NF38","076065","Immunology/Inflammation","NOS","Immunology & Inflammation","Amcinonide (Cyclocort, CL-34699) is an inhibitor of nitric oxide (NO) release from activated microglia with IC50 of 3.38 nM.",502.57,"51022-69-6",84,167.14,84,167.14,"http://www.selleckchem.com/products/amcinonide.html","C28H35FO7","Free Base","Cyclocort, CL-34699","CC(=O)OCC(=O)C12OC3(CCCC3)OC1CC4C5CCC6=CC(=O)C=CC6(C)C5(F)C(O)CC24C",2.47,6,1,4]
["S5738","Megestrol","b6","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC","EP10.5, USP43-NF38, KP Ⅹ, IP2010","070646","Cancer","Estrogen/progestogen Receptor","Endocrinology & Hormones","Megestrol, a synthetic progestin, is approved for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with an acquired immunodeficiency syndrome diagnosis. Megestrol acetate (Megace) is one of the first progestational agents to be evaluated for use in the hormonal therapy of advanced breast cancer.",342.47,"3562-63-8",68,198.56,"<1",0,"http://www.selleckchem.com/products/megestrol.html","C22H30O3","Free Base","Megace","CC(=O)C1(O)CCC2C3C=C(C)C4=CC(=O)CCC4(C)C3CCC12C",3.126,2,0,1]
["S5770","Pizotifen","c6","L1300-33","in 10mM DMSO","CFDA",null,null,"Neurological Disease","5-HT Receptor","Neuronal Signaling","Pizotifen (Pizotyline, BC-105) is a potent antagonist of 5-Hydroxytryptamine (5-HT, Serotonin) 5-HT2 receptor with a high affinity for 5-HT1C binding site.",295.44,"15574-96-6",20,67.7,"<1",0,"http://www.selleckchem.com/products/pizotifen.html","C19H21NS","Free Base","Pizotyline, BC-105","CN1CCC(CC1)=C2C3=C(CCC4=CC=CC=C24)SC=C3",4.338,0,0,0]
["S5777","Ipratropium bromide monohydrate","d6","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5 , USP43-NF38, KP Ⅹ, JP17, IP2010","074755","Immunology","AChR","Neuronal Signaling","Ipratropium bromide (Atrovent, Sch 1000) monohydrate is an antagonist of muscarinic acetylcholine receptors (mAChR) with IC50 of 2.9 nM, 2.0 nM, and 1.7 nM for M1, M2, and M3 receptors, respectively.",430.38,"66985-17-9",86,199.82,86,199.82,"http://www.selleckchem.com/products/ipratropium-bromide-monohydrate.html","C20H32BrNO4","Monohydrate","Atrovent, Sch 1000 monohydrate","O.[Br-].CC(C)[N+]1(C)C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",-1.533,2,1,6]
["S5785","Norethindrone acetate","e6","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP17, Ph.Int_5th , IP2010","075951","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Norethindrone acetate (19-Norethindrone acetate, NA) is a common synthetic hormone used in oral contraceptives. Norethindrone acetate is a well-tolerated, effective option to manage pain and bleeding for all stages of endometriosis.",340.46,"51-98-9",68,199.73,"<1",0,"http://www.selleckchem.com/products/norethindrone-acetate.html","C22H28O3","Free Base","19-Norethindrone acetate, NA","CC(=O)OC1(CCC2C3CCC4=CC(=O)CCC4C3CCC12C)C#C",4.694,3,0,2]
["S5786","Bromfenac sodium hydrate","f6","L1300-33","in 10mM DMSO","FDA, DMF, EMA, CFDA, NDC, PMDA",null,"201211","Inflammation/Ophthalmology","COX","Immunology & Inflammation","Bromfenac sodium hydrate (Bromsite, Bromday, Prolensa, Xibrom), a brominated nonsteroidal anti-inflammatory drugs (NSAID) with strong in vitro anti-inflammatory potency, is a potent and orally active inhibitor of COX with IC50 of 5.56 nM and 7.45 nM for COX-1 and COX-2, respectively.",766.34,"120638-55-3",100,130.49,100,130.49,"http://www.selleckchem.com/products/bromfenac-sodium-hydrate.html","C30H28Br2N2Na2O9","Sodium hydrate","Bromsite, Bromday, Prolensa, Xibrom","O.O.O.[Na+].[Na+].NC1=C(CC([O-])=O)C=CC=C1C(=O)C2=CC=C(Br)C=C2.NC3=C(CC([O-])=O)C=CC=C3C(=O)C4=CC=C(Br)C=C4",2.231,2,2,8]
["S5789","Propafenone","g6","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, JP17","075203","Cardiovascular Disease","Adrenergic Receptor,Sodium Channel","Endocrinology & Hormones","Propafenone (SA-79) is an orally active sodium channel blocking agent and a beta-adrenoceptor (β-adrenergic receptor) antagonist. Propafenone offers a broad spectrum of activity in the treatment of cardiac arrhythmias.",341.44,"54063-53-5",68,199.16,"<1",0,"http://www.selleckchem.com/products/propafenone.html","C21H27NO3","Free Base","SA-79","CCCNCC(O)COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2",3.673,2,2,11]
["S5860","Larotrectinib","h6","L1300-33","in 10mM DMSO","FDA, EMA, NDC",null,"210861","Cancer","Trk receptor","Protein Tyrosine Kinase","Larotrectinib (Vitrakvi, LOXO-101, ARRY-470) is an ATP-competitive, oral administered and highly selective inhibitor of the tropomyosin-related kinase (TRK) family receptors.",428.44,"1223403-58-4",86,200.73,"<1",0,"http://www.selleckchem.com/products/larotrectinib.html","C21H22F2N6O2","Free Base","Vitrakvi, LOXO-101, ARRY-470","OC1CCN(C1)C(=O)NC2=C3N=C(C=C[N]3N=C2)N4CCCC4C5=CC(=CC=C5F)F",1.981,3,2,3]
["S5864","Levocetirizine","a7","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA",null,"210914","Immunology","Histamine Receptor","Neuronal Signaling","Levocetirizine (LCZ, (R)-Cetirizine), the R-enantiomer of cetirizine, is an antagonist of histamine H(1) receptor.",388.89,"130018-77-8",78,200.57,78,200.57,"http://www.selleckchem.com/products/levocetirizine.html","C21H25ClN2O3","Free Base","LCZ, (R)-Cetirizine","OC(=O)COCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3",0.453,2,0,8]
["S5888","Beclamide","b7","L1300-33","in 10mM DMSO","CFDA",null,null,"Neurological Disease","Others","Others","Beclamide (N-Benzyl-3-chloropropionamide, beta-chlorpropionamide) exhibits sedative and anticonvulsant properties.",197.66,"501-68-8",40,202.37,"<1",0,"http://www.selleckchem.com/products/beclamide.html","C10H12ClNO","Free Base","N-Benzyl-3-chloropropionamide, beta-chlorpropionamide","ClCCC(=O)NCC1=CC=CC=C1",1.738,1,1,4]
["S5898","Efonidipine hydrochloride monoethanolate","c7","L1300-33","in 10mM DMSO","PMDA",null,null,"Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Efonidipine (NZ-105) hydrochloride monoethanolate is an L- and T-type calcium channel blocker leading to vasodilation and decreased automaticity of the heart. Efonidipine hydrochloride monoethanolate also suppresses aldosterone secretion from the adrenal.",714.18,"111011-76-8",100,140.02,"<1",0,"http://www.selleckchem.com/products/efonidipine-hydrochloride-monoethanolate.html","C36H45ClN3O8P","Hydrochloride monoethanolate","NZ-105 hydrochloride monoethanolate","Cl.CCO.CC1=C(C(C2=CC(=CC=C2)[N+]([O-])=O)C(=C(C)N1)[P]3(=O)OCC(C)(C)CO3)C(=O)OCCN(CC4=CC=CC=C4)C5=CC=CC=C5",5.329,4,2,11]
["S5922","L-Carnitine hydrochloride","d7","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38","075567","Metabolic Disease","Leukotriene","Metabolism","L-Carnitine ((R)-Carnitine, Levocarnitine) hydrochloride improves oxygen saturation, and inhibits leukotriene synthesis. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation.",197.66,"6645-46-1",40,202.37,40,202.37,"http://www.selleckchem.com/products/l-carnitine-hydrochloride.html","C7H16ClNO3","Hydrochloride","(R)-Carnitine hydrochloride, Levocarnitine hydrochloride","[Cl-].C[N+](C)(C)CC(O)CC(O)=O",-4.49,1,1,4]
["S5937","DL-Carnitine","e7","L1300-33","in 10mM DMSO","DMF",null,null,"Metabolic Disease","Others","Others","DL-Carnitine ((±)-Carnitin) is a racemic mixture of L-Carnitine and D-Carnitine that regulates fatty acid transport in the mitochondrion. DL-carnitine is found to be ineffective or toxic, for example, to muscle cells and to the myocardium. DL-Carnitine causes symptoms of myasthenia and cardiac arrhythmias.",161.2,"461-06-3, 406-76-8",32,198.51,32,198.51,"http://www.selleckchem.com/products/dl-carnitine.html","C7H15NO3","Free Base","(±)-Carnitin","C[N+](C)(C)CC(O)CC([O-])=O",-3.29,0,1,4]
["S5942","Bisoprolol","f7","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.4, USP43-NF38, KP Ⅹ, JP17","075474","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Bisoprolol is a cardioselective β1-adrenergic blocking agent used for secondary prevention of myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension.",325.44,"66722-44-9","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/bisoprolol.html","C18H31NO4","Free Base","N/A","CC(C)NCC(O)COC1=CC=C(COCCOC(C)C)C=C1",2.031,3,2,12]
["S5945","Alverine","g7","L1300-33","in 10mM DMSO","DMF","EP10.4",null,"Gastroenterology","Others","Others","Alverine is a smooth muscle relaxant.",281.44,"150-59-4","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/alverine.html","C20H27N","Free Base","N/A","CCN(CCCC1=CC=CC=C1)CCCC2=CC=CC=C2",5.39,0,0,9]
["S5947","Amitriptyline","h7","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.4, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP17, IP2010","040218","Neurological Disease","5-HT Receptor,Histamine Receptor,Serotonin Transporter","Neuronal Signaling","Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. Amitriptyline is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. This product is a waxy solid.",277.4,"50-48-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/amitriptyline.html","C20H23N","Free Base","MK-230, N-750, Ro41575","CN(C)CC\\C=C1/C2=C(CCC3=CC=CC=C13)C=CC=C2",4.772,0,0,3]
["S5949","Metoclopramide hydrochloride hydrate","a8","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP17, IP2010","070184","Gastroenterology","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Metoclopramide hydrochloride (Clorpa, Gimoti, Maxolon, Reglan) hydrate is primarily a Dopamine receptor antagonist, with 5HT3 receptor antagonist and 5HT4 receptor agonist activity, and used as an antiemetic and gastroprokinetic.",354.27,"54143-57-6",71,200.41,71,200.41,"http://www.selleckchem.com/products/metoclopramide-hydrochloride-hydrate.html","C14H25Cl2N3O3","Hydrochloride hydrate","Clorpa, Gimoti, Maxolon, Reglan","O.Cl.CCN(CC)CCNC(=O)C1=CC(=C(N)C=C1OC)Cl",1.95,2,2,7]
["S5953","Menadione bisulfite sodium","b8","L1300-33","in 10mM DMSO","CFDA",null,null,"Others","CDK,DNA/RNA Synthesis,phosphatase","Metabolism","Menadione(Vitamin K3) bisulfite sodium, a fat-soluble compound, is an inhibitor of Cdc25 phosphatase and mitochondrial DNA polymerase γ (pol γ), used as a nutritional supplement.",276.24,"130-37-0",55,199.1,55,199.1,"http://www.selleckchem.com/products/menadione-bisulfite-sodium.html","C11H9NaO5S","Sodium","Menadione sodium bisulfite, Vitamin K3 sodium bisulfite","[Na+].CC1(CC(=O)C2=CC=CC=C2C1=O)[S]([O-])(=O)=O",-1.282,2,0,1]
["S5954","L-(-)-α-Methyldopa hydrate","c8","L1300-33","in 10mM DMSO","DMF,CFDA,NDC,FDA,PMDA",null,null,"Cardiovascular Disease","Adrenergic Receptor","Endocrinology & Hormones","L-(-)-α-Methyldopa (Methyldopa, MK-351) hydrate, a potent antihypertensive drug, is a selective agonist for α2-adrenergic receptors.",476.47,"41372-08-1",46,96.54,"<1",0,"http://www.selleckchem.com/products/l-a-methyldopa-hydrate.html","C20H32N2O11","Hydrate","Methyldopa hydrate, MK-351 hydrate","O.O.O.CC(N)(CC1=CC(=C(O)C=C1)O)C(O)=O.CC(N)(CC2=CC(=C(O)C=C2)O)C(O)=O",-4.176,2,6,6]
["S5955","Thiamine nitrate","d8","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP17, IP2010","040079","Neurological Disease","Vitamin","Metabolism","Thiamine (Vitamin B1) nitrate is an essential vitamin that plays an important role in cellular production of energy from ingested food and enhances normal neuronal actives.",327.36,"532-43-4",65,198.56,20,61.09,"http://www.selleckchem.com/products/thiamine-nitrate.html","C12H17N5O4S","Nitrate","Vitamin B1 nitrate","CC1=NC=C(C[N+]2=CSC(=C2C)CCO)C(=N1)N.[O-][N+]([O-])=O",-0.914,2,2,4]
["S5957","Vardenafil hydrochloride","e8","L1300-33","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","EP10.5, USP43-NF38","091347","Others","PDE","Metabolism","Vardenafil (BAY38-9456, Levitra, Staxyn) hydrochloride is a selective, orally active, potent inhibitor of phosphodiesterase (PDE) with IC50 of 0.7 nM, 11 nM and 180 nM for PDE5, PDE6 and PDE1, respectively.",525.06,"224785-91-5",100,190.45,100,190.45,"http://www.selleckchem.com/products/vardenafil-hydrochloride.html","C23H33ClN6O4S","Hydrochloride","BAY38-9456, Levitra, Staxyn","Cl.CCCC1=NC(=C2[N]1NC(=NC2=O)C3=C(OCC)C=CC(=C3)[S](=O)(=O)N4CCN(CC)CC4)C",2.73,6,1,8]
["S5958","Metformin","f8","L1300-33","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, JP17, IP2010","075961","Endocrinology/Metabolic Disease","AMPK,Apoptosis related,JNK,Mitophagy,p38 MAPK","PI3K/Akt/mTOR","Metformin (1,1-Dimethylbiguanide), a widely used drug for treatment of type 2 diabetes, activates AMP-activated protein kinase (AMPK) in hepatocytes. Metformin promotes mitophagy in mononuclear cells. Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153.",129.16,"657-24-9",26,201.3,26,201.3,"http://www.selleckchem.com/products/metformin.html","C4H11N5","Free Base","1,1-Dimethylbiguanide","CN(C)C(=N)NC(N)=N",-0.742,0,2,3]
["S5959","Tenofovir Disoproxil","g8","L1300-33","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","Ph.Int_6th, IP2010","078800","Infection","HIV,Reverse Transcriptase","Microbiology","Tenofovir Disoproxil (Bis(POC)-PMPA, GS 4331) is a prodrug of tenofovir, which is metabolised intracellularly to its active anabolite tenofovir diphosphate, a competitive inhibitor of HIV-1 reverse transcriptase and terminates the growing DNA chain.",519.44,"201341-05-1",100,192.52,"<1",0,"http://www.selleckchem.com/products/tenofovir-disoproxil.html","C19H30N5O10P","Free Base","Bis(POC)-PMPA, GS 4331","CC(C)OC(=O)OCO[P](=O)(COC(C)C[N]1C=NC2=C(N)N=CN=C12)OCOC(=O)OC(C)C",1.69,12,1,17]
["S5960","Dabigatran etexilate mesylate","h8","L1300-33","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA",null,"207961","Angiology/Cardiovascular Disease","Thrombin","Proteases","Dabigatran etexilate mesylate (Pradaxa, BIBR 1048MS, Dabigatran etexilate methanesulfonate) is an orally active prodrug of Dabigatran which is a reversible and selective, direct thrombin inhibitor (DTI). Dabigatran selectively and reversibly inhibits human thrombin with Ki of 4.5 nM and thrombin-induced platelet aggregation with IC50 of 10 nM.",723.84,"872728-81-9",100,138.15,"<1",0,"http://www.selleckchem.com/products/dabigatran-etexilate-mesylate.html","C35H45N7O8S","Mesylate","Pradaxa, BIBR 1048MS, Dabigatran etexilate methanesulfonate","CCCCCCOC(=O)NC(=N)C1=CC=C(NCC2=NC3=C(C=CC(=C3)C(=O)N(CCC(=O)OCC)C4=CC=CC=N4)[N]2C)C=C1.C[S](O)(=O)=O",5.337,7,2,18]
["S5963","Sulfathiazole sodium","a9","L1300-33","in 10mM DMSO","FDA, DMF","EP10.5, USP43-NF38","088607","Infection","Anti-infection","Immunology & Inflammation","Sulfathiazole sodium, an antimicrobial agent, is an organosulfur compound that has been used as a short-acting sulfa drug.",277.3,"144-74-1",55,198.34,55,198.34,"http://www.selleckchem.com/products/sulfathiazole-sodium.html","C9H8N3NaO2S2","Sodium","N/A","NC1=CC=C(C=C1)[S](=O)(=O)N([Na])C2=NC=CS2",0.671,3,1,3]
["S5965","Urapidil","b9","L1300-33","in 10mM DMSO","DMF, CFDA, PMDA","JP17",null,"Cardiovascular Disease","5-HT Receptor,Adrenergic Receptor","Neuronal Signaling","Urapidil is an antihypertensive drug acting as an α1 adrenoreceptor antagonist and a 5-HT1A agonist.",387.48,"34661-75-1",77,198.72,"<1",0,"http://www.selleckchem.com/products/urapidil.html","C20H29N5O3","Free Base","N/A","COC1=CC=CC=C1N2CCN(CCCNC3=CC(=O)N(C)C(=O)N3C)CC2",1.426,3,1,7]
["S5966","Amlodipine maleate","c9","L1300-33","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, JP17, IP2010","021714","Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Amlodipine (Amvaz, UK-48340) maleate is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.",524.95,"88150-47-4",100,190.49,"<1",0,"http://www.selleckchem.com/products/amlodipine-maleate.html","C24H29ClN2O9","Maleate","Amvaz, UK-48340 maleate","CCOC(=O)C1=C(COCCN)NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C.OC(=O)\\C=C/C(O)=O",-0.864,7,2,12]
["S5969","Dicloxacillin Sodium hydrate","d9","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC","EP10.5, USP43-NF38, KP Ⅹ, JP17, IP2010","061454","Infection","Antineoplastic and Immunosuppressive Antibiotics,Immunology & Inflammation related,P450 (e.g. CYP17)","Metabolism","Dicloxacillin Sodium hydrate (DLX, Dycill, Dynapen, Pathocil), a narrow-spectrum β-Lactam antibiotic of the penicillin class, induces drug-metabolizing CYP enzymes to a clinically relevant extent.",510.32,"13412-64-1",100,195.96,100,195.96,"http://www.selleckchem.com/products/dicloxacillin-sodium-hydrate.html","C19H18Cl2N3NaO6S","Sodium hydrate","DLX, Dycill, Dynapen, Pathocil","O.[Na+].CC1=C(C(=O)NC2C3SC(C)(C)C(N3C2=O)C([O-])=O)C(=NO1)C4=C(Cl)C=CC=C4Cl",1.283,4,1,4]
["S5971","Pemetrexed","e9","L1300-33","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","EP10.5, USP43-NF38","090352","Cancer","Apoptosis related,Autophagy,DHFR,DNA/RNA Synthesis,Thymidylate Synthase","Apoptosis","Pemetrexed (LY231514, Alimta) is a novel antifolate and antimetabolite for thymidylate synthase (TS), dihydrofolate reductase (DHFR) and glycinamide ribonucleotide formyltransferase (GARFT) with Ki of 1.3 nM, 7.2 nM and 65 nM in cell-free assays, respectively. Pemetrexed induces autophagy and apoptosis.",427.41,"137281-23-3",85,198.87,"<1",0,"http://www.selleckchem.com/products/pemetrexed.html","C20H21N5O6","Free Base","LY231514, Alimta","NC1=NC(=O)C2=C([NH]C=C2CCC3=CC=C(C=C3)C(=O)NC(CCC(O)=O)C(O)=O)N1",1.144,5,4,9]
["S5972","Hydrocortisone hemisuccinate","f9","L1300-33","in 10mM DMSO","DMF","USP43-NF38, KP Ⅹ, JP17, IP2010",null,"Endocrinology/Gastrointestinal Disease/Inflammation/Infection/Hematology","Interleukins","Immunology & Inflammation","Hydrocortisone hemisuccinate (A-hydrocort, Hydrocortisone 21-hemisuccinate), a physiological glucocorticoid with anti-inflammatory properties, is an inhibitor of proinflammatory cytokine with IC50 of 6.7 μM and 21.4 μM for Interleukin-6 (IL-6) and IL-3, respectively.",462.53,"2203-97-6",93,201.07,"<1",0,"http://www.selleckchem.com/products/hydrocortisone-hemisuccinate.html","C25H34O8","Hemisuccinate","A-hydrocort, Hydrocortisone 21-hemisuccinate","CC12CCC(=O)C=C1CCC3C4CCC(O)(C(=O)COC(=O)CCC(O)=O)C4(C)CC(O)C23",1.507,5,1,7]
["S5973","Methylprednisolone Acetate","g9","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, JP17, IP2010","040557","Endocrinology/Gastrointestinal Disease/Inflammation/Infection/Hematology","ACE,Apoptosis related,Autophagy,Glucocorticoid Receptor,Immunology & Inflammation related,Interleukins","Endocrinology & Hormones","Methylprednisolone (NSC-19987, Medrol) acetate is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.",416.51,"53-36-1",86,206.48,"<1",0,"http://www.selleckchem.com/products/methylprednisolone-acetate.html","C24H32O6","Free Base","NSC-19987 acetate, Medrol acetate","CC1CC2C3CCC(O)(C(=O)COC(C)=O)C3(C)CC(O)C2C4(C)C=CC(=O)C=C14",1.891,4,1,4]
["S5981","S(-)-Propranolol hydrochloride","h9","L1300-33","in 10mM DMSO","DMF,EMA,HMA,NDC,FDA,PMDA","JP15,USP32-NF27",null,"Cardiovascular Disease","Adrenergic Receptor","Endocrinology & Hormones","(S)-(-)-Propranolol hydrochloride, the active enantiomer of propranolol, is a β-Adrenoceptor (β-Adrenergic Receptor) antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively.",295.8,"4199-10-4",59,199.46,59,199.46,"http://www.selleckchem.com/products/s-propranolol-hydrochloride.html","C16H22ClNO2","Hydrochloride","Hemangeol, Inderal","Cl.CC(C)NCC(O)COC1=CC=CC2=CC=CC=C12",2.922,1,2,6]
["S6359","Purine","a10","L1300-33","in 10mM DMSO","DMF","USP43-NF38, IP2010",null,"Others","DNA/RNA Synthesis","DNA Damage/DNA Repair","Purine is a heterocyclic aromatic organic compound which plays crucial roles in DNA and RNA. It is also significant components in a number of other important biomolecules, such as ATP, GTP, cyclic AMP, NADH, and coenzyme A.",120.11,"120-73-0",24,199.81,0,0,"https://www.selleckchem.com/products/purine.html","C5H4N4","Free Base","N/A","[NH]1C=NC2=C1N=CN=C2",-0.235,3,1,0]
["S6437","Oxolamine Citrate","b10","L1300-33","in 10mM DMSO","CFDA",null,null,"Respiratory Disease","P450 (e.g. CYP17)","Metabolism","Oxolamine (SKF-9976, AF-438) citrate, a cough suppressant, is an inhibitor of CYP2B1/2. Oxolamine citrate also exhibits anti-inflammatory effect.",437.44,"1949-20-8",87,198.88,43,98.3,"http://www.selleckchem.com/products/oxolamine-citrate.html","C20H27N3O8","Citrate","SKF-9976 citrate, AF-438 citrate","CCN(CC)CCC1=NC(=NO1)C2=CC=CC=C2.OC(=O)CC(O)(CC(O)=O)C(O)=O",-1.921,6,0,11]
["S6463","Sodium tauroglycocholate","c10","L1300-33","in 10mM DMSO","CFDA",null,null,"Gastroenterology","Others","Others","Sodium tauroglycocholate (STGC, Tauroglycocholic acid sodium salt) is an absorption enhancer of transdermal permeation of drug.",594.74,"41945-48-6",100,168.14,100,168.14,"http://www.selleckchem.com/products/sodium-tauroglycocholate.html","C28H47N2NaO8S","Sodium","STGC, Tauroglycocholic acid sodium salt","[Na+].CC(CCC(=O)NCC(=O)NCC[S]([O-])(=O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CC(O)C12C",-1.29,2,5,9]
["S6466","Eicosapentaenoic acid ethyl ester","d10","L1300-33","in 10mM DMSO","FDA, DMF, NDC, PMDA",null,null,"Hematology","Fatty Acid Synthase","Metabolism","Eicosapentaenoic acid ethyl ester (AMR101, EPA ethyl ester, Ethyl eicosapentaenoate) is an omega-3 fatty acid agent that significantly reduces the triglyceride (TG) levels and improves other lipid parameters without significantly increasing the low-density lipoprotein (LDL) cholesterol levels.",330.5,"86227-47-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/eicosapentaenoic-acid-ethyl-ester.html","C22H34O2","Free Base","AMR101, EPA ethyl ester, Ethyl eicosapentaenoate","CCOC(=O)CCC\\C=C/C/C=C\\C\\C=C/C/C=C\\C\\C=C/CC",6.569,2,0,15]
["S6584","Amdinocillin","e10","L1300-33","in 10mM DMSO","DMF",null,null,"Infection","Antibiotics,Bacterial","Microbiology","Amdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms.",325.43,"32887-01-7",65,199.74,65,199.74,"http://www.selleckchem.com/products/amdinocillin.html","C15H23N3O3S","Free Base","Mecillinam, Coactin, FL 1060","CC1(C)SC2C(N=CN3CCCCCC3)C(=O)N2C1C(O)=O",1.186,3,0,3]
["S6988","Lusutrombopag","f10","L1300-33","in 10mM DMSO","FDA, EMA, PMDA, NDC",null,"210923","Hematology","TpoR","Immunology & Inflammation","Lusutrombopag (Mulpleta, S-888711) is an orally bioavailable thrombopoietin (TPO) receptor agonist being developed for chronic liver disease (CLD).",591.55,"1110766-97-6",100,169.05,"<1",0,"http://www.selleckchem.com/products/lusutrombopag.html","C29H32Cl2N2O5S","Free Base","Mulpleta, S-888711","CCCCCCOC(C)C1=CC=CC(=C1OC)C2=CSC(=N2)NC(=O)C3=CC(=C(\\C=C(/C)C(O)=O)C(=C3)Cl)Cl",7.837,5,1,13]
["S6999","Chloroquine (NSC-187208)","g10","L1300-33","in 10mM DMSO","FDA, DMF, CFDA, NDC","EP10.5, USP43-NF38, Ph.Int_6th, IP2010","040516","Infection","Autophagy,COVID-19,HIV Protease,TLR","Autophagy","Chloroquine (NSC-187208, Aralen, CHQ, CQ) is an antimalarial drug and autophagy/lysosome inhibitor. Chloroquine also suppresses Toll-like receptor-9 (TLR9) protein expression. Chloroquine is highly effective agianst SARS-CoV-2 (COVID-19) infection with EC50 of 1.13 μM in Vero E6 cells. Chloroquine has anti-HIV-1 activity.",319.87,"54-05-7",64,200.08,"<1",0,"http://www.selleckchem.com/products/chloroquine.html","C18H26ClN3","Free Base","Aralen, CHQ, CQ","CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl",4.345,1,1,8]
["S7220","Fostemsavir","h10","L1300-33","in 10mM DMSO","FDA, EMA, NDC",null,"212950","Infection","gp120/CD4","Immunology & Inflammation","Fostemsavir (BMS-663068, Rukobia), the phosphonooxymethyl prodrug of BMS626529, is an attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells with EC50 of < 10 nM.",583.49,"864953-29-7",100,171.38,"<1",0,"http://www.selleckchem.com/products/bms-663068.html","C25H26N7O8P","Free Base","BMS-663068, Rukobia","COC1=CN=C([N]2C=NC(=N2)C)C3=C1C(=C[N]3CO[P](O)(O)=O)C(=O)C(=O)N4CCN(CC4)C(=O)C5=CC=CC=C5",0.752,8,0,8]
["S8932","Remdesivir (GS-5734)","a11","L1300-33","in 10mM DMSO","FDA, EMA, NDC",null,"214787","Infection","Antiviral,COVID-19,DNA/RNA Synthesis","Microbiology","Remdesivir (GS-5734), a monophosphoramidate prodrug of an adenosine analog, is an investigational broad-spectrum antiviral agent with in vitro activity against multiple RNA viruses, including Ebola and CoV.",602.58,"1809249-37-3",100,165.95,"<1",0,"http://www.selleckchem.com/products/remdesivir.html","C27H35N6O8P","Free Base","N/A","CCC(CC)COC(=O)C(C)N[P](=O)(OCC1OC(C#N)(C(O)C1O)C2=CC=C3[N]2N=CN=C3N)OC4=CC=CC=C4",2.174,7,4,14]
["S9631","Puromycin aminonucleoside","b11","L1300-33","in 10mM DMSO","DMF",null,null,"Others","Aminopeptidase,Apoptosis related,DPP","Proteases","Puromycin aminonucleoside (NSC 3056, PAN, Stylomycin aminonucleoside, ARDMA, SAN), the aminonucleoside portion of the antibiotic puromycin, is a reversible inhibitor of dipeptidyl-peptidase II and cytosol alanyl aminopeptidase that induces apoptosis in mesangial cells (MCs) accompanied by declined cell viability and enhanced inflammatory response.",294.31,"58-60-6",59,200.47,30,101.93,"http://www.selleckchem.com/products/puromycin-aminonucleoside.html","C12H18N6O3","Free Base","NSC 3056, PAN, Stylomycin aminonucleoside, ARDMA, SAN","CN(C)C1=C2N=C[N](C3OC(CO)C(N)C3O)C2=NC=N1",-1.262,4,3,3]
["S9693","Vericiguat","c11","L1300-33","in 10mM DMSO","FDA",null,"214377","Cardiovascular Disease","Guanylate Cyclase","GPCR & G Protein","Vericiguat (BAY1021189, Verquvo) is a potent, orally available and soluble guanylate cyclase (sGC) stimulator.",426.38,"1350653-20-1",85,199.35,"<1",0,"http://www.selleckchem.com/products/vericiguat.html","C19H16F2N8O2","Free Base","BAY1021189, Verquvo","COC(=O)NC1=C(N)N=C(N=C1N)C2=N[N](CC3=CC=CC=C3F)C4=NC=C(F)C=C24",2.341,6,3,5]
["S9715","Lanraplenib (GS-9876)","d11","L1300-33","in 10mM DMSO","FDA",null,null,"Immunology","Syk","Angiogenesis","Lanraplenib (GS-9876, GS-SYK) is a potent, highly selective and orally active inhibitor of Spleen Tyrosine Kinase (SYK) with IC50 of 9.5 nM. Lanraplenib inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.",443.5,"1800046-95-0",89,200.68,"<1",0,"http://www.selleckchem.com/products/lanraplenib.html","C23H25N9O","Free Base","GS-SYK","NC1=CN=CC(=N1)C2=C[N]3C=CN=C3C(=N2)NC4=CC=C(C=C4)N5CCN(CC5)C6COC6",1.211,5,2,5]
["S9783","6-Aminonicotinamide","e11","L1300-33","in 10mM DMSO","DMF",null,null,"Cancer","Dehydrogenase","Metabolism","6-Aminonicotinamide (6AN) is an antimetabolite used to inhibit the NADPH-producing pentose phosphate pathway (PPP) in many cellular systems, making them more susceptible to oxidative stress. 6-Aminonicotinamide is a competitive inhibitor of NADP+-dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) with Ki of 0.46 μM.",137.14,"329-89-5",27,196.88,"<1",0,"http://www.selleckchem.com/products/6-aminonicotinamide.html","C6H7N3O","Free Base","6AN","NC(=O)C1=CC=C(N)N=C1",-0.526,2,2,1]
["S9827","Iodoacetamide","f11","L1300-33","in 10mM DMSO",null,"EP10.5",null,"Others","Others","Others","Iodoacetamide (IA, IAM, 2-Iodoacetamide) is an alkylating agent that is commonly used for alkylation of cysteine during sample preparation for proteomics.",184.96,"144-48-9",40,216.26,40,216.26,"http://www.selleckchem.com/products/iodoacetamide.html","C2H4INO","Free Base","IA, IAM, 2-Iodoacetamide","NC(=O)CI",0.376,1,1,1]
["S0993","Remogliflozin etabonate (GSK189075)","g11","L1300-33","in 10mM DMSO","Marketed in India",null,null,"Metabolic Disease","SGLT","GPCR & G Protein","Remogliflozin etabonate (GSK189075) is an orally active, selective and low-affinity inhibitor of sodium glucose cotransporter (SGLT2) with Ki of 1950 nM, 2140 nM, 43100 nM, 8570 nM for hSGLT2, rSGLT2, hSGLT1, rSGLT1, respectively. Remogliflozin etabonate exhibits antidiabetic efficacy in rodent models.",522.59,"442201-24-3",100,191.35,"<1",0,"http://www.selleckchem.com/products/remogliflozin-etabonate.html","C26H38N2O9","Free Base","N/A","CCOC(=O)OCC1OC(OC2=N[N](C(C)C)C(=C2CC3=CC=C(OC(C)C)C=C3)C)C(O)C(O)C1O",3.774,7,3,12]
["S4485","Olodaterol (BI 1744)","h11","L1300-33","in 10mM DMSO","FDA, NDC",null,206756,"Inflammation","Adrenergic Receptor","Endocrinology & Hormones","Olodaterol (BI 1744) is a long-acting β2-adrenergic receptor agonist that is used as a component of an inhalation (Tiotropium/Olodaterol) for treating patients with chronic obstructive pulmonary disease (COPD).",386.44,"868049-49-4",77,199.25,"<1",0,"http://www.selleckchem.com/products/olodaterol-bi-1744-.html","C21H26N2O5","Free Base","N/A","COC1=CC=C(CC(C)(C)NCC(O)C2=C3OCC(=O)NC3=CC(=C2)O)C=C1",1.875,3,4,7]
["S5899","(R)-(-)-Ibuprofen","a2","L1300-34","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC","USP–NF 2021(Issue 2), EP10.5, Ph.Int_6th, JP17, IP2010","070038","Inflammation","NF-κB","NF-κB","(R)-(-)-Ibuprofen ((R)-Ibuprofen) inhibits the activation of NF-κB in response to T-cell stimulation with IC50 of 121.8 μM, and exerts anti-inflammatory and antinociceptive effects.",206.28,"51146-57-7",41,198.76,41,198.76,"http://www.selleckchem.com/products/-r-ibuprofen.html","C13H18O2","Free Base","(R)-Ibuprofen","CC(C)CC1=CC=C(C=C1)C(C)C(O)=O",3.607,1,0,4]
["S5910","Alpha-Estradiol","b2","L1300-34","in 10mM DMSO","FDA, DMF, NDC","EP10.5","020655","others","Estrogen/progestogen Receptor","Endocrinology & Hormones","Alpha-Estradiol (α-Estradiol, 17 alpha-Estradiol, Alfatradiol, Epiestradiol, Epiestrol, Alora, 17 α-E2), a natural, non-feminizing stereoisomer, a hormonally almost inactive isomer of physiological 17 beta-estradiol (17 β-E2), is a weak inhibitor of estrogen.",272.38,"57-91-0",54,198.25,"<1",0,"http://www.selleckchem.com/products/alpha-estradiol.html","C18H24O2","Free Base","α-Estradiol, 17alpha-Estradiol, Alfatradiol, Epiestradiol, Epiestrol, Alora, 17 α-E2","CC12CCC3C(CCC4=C3C=CC(=C4)O)C1CCC2O",3.838,0,2,0]
["S6909","Levomefolic acid","c2","L1300-34","in 10mM DMSO","FDA",null,null,"Cardiovascular system","DNA/RNA Synthesis","DNA Damage/DNA Repair","Levomefolic acid (5-MTHF, LMSR, Metafolin, Nutrifolin) is a natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions.",459.46,"31690-09-2",46,100.12,"<1",0,"http://www.selleckchem.com/products/levomefolic-acid.html","C20H25N7O6","Free Base","5-MTHF, LMSR, Metafolin, Nutrifolin","CN1C(CNC2=CC=C(C=C2)C(=O)NC(CCC(O)=O)C(O)=O)CNC3=C1C(=O)N=C(N)N3",-0.794,5,5,9]
["S6981","Glycerol phenylbutyrate","d2","L1300-34","in 10mM DMSO","FDA, DMF, EMA,NDC",null,205742,"Metabolic Disease","Sigma Receptor","GPCR & G Protein","Glycerol phenylbutyrate (GT4P, HPN-100M, Ravicti) is a nitrogen-binding agent and acts as a sigma-2 (σ2) receptor ligand with a pKi of 8.02. Glycerol phenylbutyrate is a prodrug in which phenylbutyrate (PBA) is released from the glycerol backbone by lipases in the gastrointestinal tract.",530.65,"611168-24-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/glycerol-phenylbutyrate.html","C33H38O6","Free Base","GT4P, HPN-100M, Ravicti","O=C(CCCC1=CC=CC=C1)OCC(COC(=O)CCCC2=CC=CC=C2)OC(=O)CCCC3=CC=CC=C3",7.563,6,0,20]
["S6985","Varenicline","e2","L1300-34","in 10mM DMSO","FDA, DMF, EMA, CFDA, NDC, PMDA",null,201785,"others","AChR","Neuronal Signaling","Varenicline(CP 526555) is highly selective and blocks more potently to α4β2 receptors than to other common nicotinic receptors (>500-fold α3β4, >3,500-fold α7, >20,000-fold α1βγδ), or to non-nicotinic receptors and transporters (>2,000-fold). Varenicline also acts as an agonist of 5-HT3 serotonine receptors.",211.26,"249296-44-4",42,198.81,3,14.2,"http://www.selleckchem.com/products/varenicline.html","C13H13N3","Free Base","Chantix, Champix,CP 526555","C1NCC2CC1C3=CC4=NC=CN=C4C=C23",1.038,2,1,0]
["S6987","Iron Dextran","f2","L1300-34","in 10mM DMSO","FDA, DMF, CFDA, NDC","USP–NF 2021(Issue 2), IP2010","010787","others","Others","Others","Iron dextran (Fero Gradumet, Conferon, Fe dextran, INFeD) is an anti-anemia drug that can be used in the study of iron-deficiency anemia in animals.",153.92,"9004-66-4","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/iron-dextran.html","FeH2O4S","Free Base","Fero Gradumet, Conferon, Fe dextran, INFeD","[Fe].O[S](O)(=O)=O",-0.607,0,0,0]
["E0006","Gadoteridol","g2","L1300-34","in 10mM DMSO","FDA, DMF, PMDA","USP–NF 2021(Issue 2)","020131","others","Others","Others","Gadoteridol (ProHance, SQ-32692, Gd-HP-DO3A) is a nonionic contrast agent for magnetic resonance imaging (MRI).",558.68,"120066-54-8",100,178.99,100,178.99,"http://www.selleckchem.com/products/gadoteridol.html","C17H29GdN4O7","Free Base","ProHance, SQ-32692, Gd-HP-DO3A","[Gd+3].CC(O)CN1CCN(CCN(CCN(CC1)CC([O-])=O)CC([O-])=O)CC([O-])=O",-5.585,0,1,8]
["E0007","Isosulfan Blue","h2","L1300-34","in 10mM DMSO","FDA, DMF, NDC",null,"090874","others","Dyes","Others","Isosulfan Blue (Lymphazurin dye) is a blue dye used as a visual imaging agent in lymph node mapping procedures.",566.66,"68238-36-8",100,176.47,100,176.47,"http://www.selleckchem.com/products/isosulfan-blue.html","C27H31N2NaO6S2","Free Base","Lymphazurin dye","[Na+].CCN(CC)C1=CC=C(C=C1)C(=C2C=CC(C=C2)=[N+](CC)CC)C3=C(C=CC(=C3)[S]([O-])(=O)=O)[S]([O-])(=O)=O",0.333,0,0,9]
["E0018","Triheptanoin","a3","L1300-34","in 10mM DMSO","FDA, DMF",null,213687,"Metabolic Disease","Others","Others","Triheptanoin (API, IND106011, UX007, Glycerol trienanthate) is a synthetic, medium-chain triglyceride consisting of three odd-chain 7-carbon (heptanoate) fatty acids on a glycerol backbone. Triheptanoin is used for treatment of fatty acid oxidation disorders and GLUT1.",428.6,"620-67-7","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,0,"http://www.selleckchem.com/products/triheptanoin.html","C24H44O6","Free Base","IND106011, UX007, Glycerol trienanthate","CCCCCCC(=O)OCC(COC(=O)CCCCCC)OC(=O)CCCCCC",7.204,6,0,23]
["E0019","Dipivefrin Hydrochloride","b3","L1300-34","in 10mM DMSO","FDA, DMF, CFDA","USP–NF 2021(Issue 2), EP10.4","073636","Ophthalmology","Others","Others","Dipivefrin (Dipivefrine,  Propine, Pivalephrine) is a prodrug of epinephrine which is hydrolyzed to epinephrine after absorption into the eye.",387.9,"64019-93-8",78,201.08,78,201.08,"http://www.selleckchem.com/products/dipivefrin-hydrochloride.html","C19H30ClNO5","Hydrochloride","Dipivefrine,  Propine, Pivalephrine","Cl.CNCC(O)C1=CC(=C(OC(=O)C(C)(C)C)C=C1)OC(=O)C(C)(C)C",3.866,4,2,9]
["S0897","Cyclizine","c3","L1300-34","in 10mM DMSO","FDA, CFDA","USP–NF 2021(Issue 2), EP10.5, IP2010","009495","Others","Histamine Receptor","Neuronal Signaling","Cyclizine is a piperazine first-generation antagonist of histamine 1 receptor.",266.38,"82-92-8",53,198.96,"<1",0,"http://www.selleckchem.com/products/cyclizine.html","C18H22N2","Free Base","N/A","CN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3",3.47,0,0,3]
["S6874","Propidium Iodide","d3","L1300-34","in 10mM DMSO",null,"EP10.5",null,"Others","Dyes","Others","Propidium iodide (PI) is a red-fluorescent DNA stain which penetrates only damaged cellular membranes. Propidium iodide (PI) is described for use in the determination of cell viability in cell suspension.",668.39,"25535-16-4",100,149.61,10,14.96,"http://www.selleckchem.com/products/propidium-iodide.html","C27H34N4.2I","Free Base","PI","[I-].[I-].CC[N+](C)(CC)CCC[N+]1=C2C=C(N)C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N",-2.82,0,2,7]
["S9625","Saquinavir (Ro 31-8959)","e3","L1300-34","in 10mM DMSO","FDA, EMA, PMDA","USP–NF 2021(Issue 2), EP10.5, Ph.Int_6th, IP2010","020828","Infection","HIV Protease","Microbiology","Saquinavir (Ro 31-8959,SAQ) is a potent and selective inhibitor of HIV proteinase with a mean IC50 of 2.7 nM in JM cells.",670.84,"127779-20-8",100,149.07,"<1",0,"http://www.selleckchem.com/products/saquinavir.html","C38H50N6O5","Free Base","Ro 31-8959,SAQ","CC(C)(C)NC(=O)C1CC2CCCCC2CN1CC(O)C(CC3=CC=CC=C3)NC(=O)C(CC(N)=O)NC(=O)C4=NC5=CC=CC=C5C=C4",3.67,5,5,13]
["S9925","Imeglimin (EMD 387008) Hydrochloride","f3","L1300-34","in 10mM DMSO","PMDA",null,null,"Metabolic Disease","Others","Others","Imeglimin (EMD 387008, IMEG, PXL 008, RVT-1501) Hydrochloride is a new class of oral glucose-lowering agents. Imeglimin normalizes glucose tolerance and insulin sensitivity by preserving mitochondrial function from oxidative stress and favoring lipid oxidation in liver of HFHSD mice.",191.66,"775351-61-6",38,198.27,38,198.27,"http://www.selleckchem.com/products/imeglimin-emd-387008-hydrochloride.html","C6H13N5.ClH","Hydrochloride","PXL 008 Hydrochloride, RVT-1501 Hydrochloride, IMEG Hydrochloride","Cl.CC1N=C(N)NC(=N1)N(C)C",0.03,2,2,1]
["E0037","Bradykinin","g3","L1300-34","in 10mM DMSO","NDC",null,null,"Cardiovascular Disease","Others","Others","Bradykinin is a potent vasodilator peptide that exerts its vasodilatory action through stimulation of specific endothelial B2 receptors, thereby causing the release of prostacyclin, NO, and EDHF.",1060.21,"58-82-2",100,94.32,100,94.32,"http://www.selleckchem.com/products/bradykinin.html","C50H73N15O11","Free Base","N/A","NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC(=O)NC(CC3=CC=CC=C3)C(=O)NC(CO)C(=O)N4CCCC4C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCCN=C(N)N)C(O)=O",-5.45,11,11,27]
["E0046","β-Cyclodextrin","h3","L1300-34","in 10mM DMSO","FDA, CFDA, PMDA","EP10.5, USP36-NF31",null,"Others","Others","Others","β-Cyclodextrin (β-CD, Beta-Cyclodextrin) is a cyclic derivative of starch prepared from partially hydrolyzed starch (maltodextrin) by an enzymatic process. β-Cyclodextrin can be used as complexing agents to increase aqueous solubility of poorly soluble drugs and to increase their bioavailability and stability.",1134.98,"7585-39-9",100,88.11,5,4.41,"http://www.selleckchem.com/products/beta-cyclodextrin.html","C42H70O35","Free Base","β-CD, Beta-Cyclodextrin","OCC1OC2OC3C(O)C(O)C(OC3CO)OC4C(O)C(O)C(OC4CO)OC5C(O)C(O)C(OC5CO)OC6C(O)C(O)C(OC6CO)OC7C(O)C(O)C(OC7CO)OC8C(O)C(O)C(OC8CO)OC1C(O)C2O",-12.23,14,21,7]
["E0054","Tegoprazan","a4","L1300-34","in 10mM DMSO","DMF,CFDA",null,null,"Metabolic Disease/Inflammation/Immunology","ATPase","Transmembrane Transporters","Tegoprazan (CJ-12420, IN-A001, K-CAB, LXI-15028, RQ-00000004) is a novel potent and highly selective inhibitor of gastric H+/K+-ATPase with IC50s ranging from 0.29 μM to 0.52 μM for  porcine, canine, and human H+/K+-ATPases in vitro, respectively.",387.38,"942195-55-3",77,198.77,"<1",0,"http://www.selleckchem.com/products/tegoprazan.html","C20H19F2N3O3","Free Base","CJ-12420, IN-A001, K-CAB, LXI-15028, RQ-00000004","CN(C)C(=O)C1=CC2=C(N=C(C)[NH]2)C(=C1)OC3CCOC4=C3C(=CC(=C4)F)F",2.89,4,1,3]
["E0110","Baloxavir","b4","L1300-34","in 10mM DMSO","FDA, EMA, PMDA",null,"210854","Infection","Antiviral","Microbiology","Baloxavir (Baloxavir acid, S-033447) is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor with an IC50 of 2.5 nM. BXA inhibits viral RNA transcription via selective inhibition of CEN activity.",483.49,"1985605-59-1",25,51.71,"<1",0,"http://www.selleckchem.com/products/baloxavir.html","C24H19F2N3O4S","Free Base","Baloxavir acid, S-033447","OC1=C2N(C=CC1=O)N(C3COCCN3C2=O)C4C5=C(CSC6=CC=CC=C46)C(=C(F)C=C5)F",1.91,3,1,1]
["E0144","Vernakalant (RSD1235) Hydrochloride","c4","L1300-34","in 10mM DMSO","EMA",null,null,"Cardiovascular Disease","Potassium Channel,Sodium Channel","Transmembrane Transporters","Vernakalant (RSD-1235, MK-6621) is a novel, frequency-dependent Na+ channel and early activating K+ channel blocker that selectively prolongs the atrial refractory period.",385.93,"748810-28-8",77,199.52,77,199.52,"http://www.selleckchem.com/products/vernakalant-rsd1235-hydrochloride.html","C20H31NO4.ClH","Hydrochloride","MK-6621","Cl.COC1=C(OC)C=C(CCOC2CCCCC2N3CCC(O)C3)C=C1",3.24,3,1,7]
["E0148","Linalyl Acetate","d4","L1300-34","in 10mM DMSO",null,"EP10.5",null,"Others","Immunology & Inflammation related","Immunology & Inflammation","Linalyl Acetate (Bergamiol, Bergamol, Linalool acetate) is a naturally occurring phytochemical found in many flowers and spice plants. Linalyl Acetate is a potentially anti-inflammatory agent.",196.29,"115-95-7",0,"The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,"http://www.selleckchem.com/products/linalyl-acetate.html","C12H20O2","Free Base","Bergamiol, Bergamol, Linalool acetate","CC(C)=CCCC(C)(OC(C)=O)C=C",3.11,2,0,6]
["E0153","Lithium Chloride","e4","L1300-34","in 10mM DMSO","NDC","USP–NF 2021(Issue 2), EP10.5, IP2010",null,"Others","Antiviral","Microbiology","Lithium Chloride (LiCl) inhibits the replication of type 1 and type 2 Herpes simplex virus at concentrations which permitted host cell replication. Lithium chloride also prevents glucocorticoid-induced osteonecrosis of femoral heads and strengthens mesenchymal stem cell activity in rats.",42.39,"7447-41-8",8,188.72,8,188.72,"http://www.selleckchem.com/products/lithium-chloride.html","ClLi","Free Base","LiCl","[Li+].[Cl-]",-2.67,0,0,0]
["E0154","Taurocholic acid sodium salt","f4","L1300-34","in 10mM DMSO",null,"USP–NF 2021(Issue 2)",null,"Others","Others","Others","Taurocholic acid sodium salt (Sodium Taurocholate, TANa) is a sodium salt of taurocholic acid and occurs in the bile of mammals. Taurocholic acid  is used as a cholagogue and choleretic.",537.68,"145-42-6",100,185.98,100,185.98,"http://www.selleckchem.com/products/taurocholic-acid-sodium-salt.html","C26H45NO7S.Na","Sodium salt","Sodium Taurocholate, TANa","[Na+].CC(CCC(=O)NCC[S]([O-])(=O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CC(O)C12C",-0.35,1,4,7]
["E0156","Thioacetamide","g4","L1300-34","in 10mM DMSO",null,"USP–NF 2021(Issue 2), EP10.5, IP2010",null,"Others","Others","Others","Thioacetamide (TAA) is a hepatotoxin frequently used for experimental purposes which produces centrilobular necrosis after a single dose administration.",75.13,"62-55-5",15,199.65,15,199.65,"http://www.selleckchem.com/products/thioacetamide.html","C2H5NS","Free Base","TAA","CC(N)=S",0.04,0,1,0]
["E0160","Hexaminolevulinate hydrochloride","h4","L1300-34","in 10mM DMSO","FDA",null,"022555","Others","Others","Others","Hexaminolevulinate hydrochloride (5-Aminolevulinic acid hexyl ester hydrochloride) is a tumour photosensitizer.",251.75,"140898-91-5",50,198.61,50,198.61,"http://www.selleckchem.com/products/hexaminolevulinate-hydrochloride.html","C11H21NO3.ClH","Hydrochloride","5-Aminolevulinic acid hexyl ester hydrochloride","Cl.CCCCCCOC(=O)CCC(=O)CN",1.63,3,1,10]
["E0165","Phenelzine sulfate","a5","L1300-34","in 10mM DMSO","FDA, NDC","USP–NF 2021(Issue 2)","200181","Neurological Disease","MAO","Neuronal Signaling","Phenelzine Sulfate is a hydrazine derivative and acts as a potent non-selective monoamine oxidase (MAO) inhibitor with an IC50 of 0.9 μM.",234.27,"156-51-4",47,200.62,47,200.62,"http://www.selleckchem.com/products/phenelzine-sulfate.html","C8H12N2.H2O4S","Sulfate","N/A","NNCCC1=CC=CC=C1.O[S](O)(=O)=O",0.31,0,2,3]
["E0167","Tazobactam Sodium","b5","L1300-34","in 10mM DMSO","FDA, EMA, HMA, CFDA, PMDA, NDC",null,"065362","Infection","Selection Antibiotics for Transfected Cell,β-lactamase","Microbiology","Tazobactam (Tazobactam acid, Tazobactamum) Sodium is a beta-lactamase inhibitor that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms.",323.28,"89785-84-2",65,201.06,65,201.06,"http://www.selleckchem.com/products/tazobactam-sodium.html","C10H12N4O5S.Na","Sodium","Tazobactam acid Sodium, Tazobactamum Sodium","[NaH].CC1(C[N]2C=CN=N2)C(N3C(CC3=O)[S]1(=O)=O)C(O)=O",-1.19,6,0,3]
["E0169","Zinc acetate","c5","L1300-34","in 10mM DMSO","FDA, CFDA, PMDA, NDC","USP–NF 2021(Issue 2), EP10.5, Ph.Int_6th","020458","Others","Others","Others","Zinc acetate induces the expression of enterocyte metallothionein.",183.48,"557-34-6",37,201.66,37,201.66,"http://www.selleckchem.com/products/zinc-acetate.html","C4H6O4Zn","Free Base","N/A","CC(=O)O[Zn]OC(C)=O",-0.23,4,0,4]
["E0172","Imidacloprid","d5","L1300-34","in 10mM DMSO",null,"EP10.5",null,"Others","AChR","Neuronal Signaling","Imidacloprid is a nicotinic acetylcholine receptor (nAChR) agonist with potent insecticidal activity.",255.66,"138261-41-3",51,199.48,"<1",0,"http://www.selleckchem.com/products/imidacloprid.html","C9H10ClN5O2","Free Base","N/A","[O-][N+](=O)\\N=C1/NCCN1CC2=CC=C(Cl)N=C2",3.7,2,1,3]
["E0174","Betamethasone sodium phosphate","e5","L1300-34","in 10mM DMSO","FDA, CFDA, PMDA, NDC","JP18, USP–NF 2021(Issue 2), EP10.5, KP Ⅹ, IP2010","085738","Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Betamethasone sodium phosphate (Betamethasone 21-Phosphate Disodium Salt) is a potent glucocorticoid with anti-inflammatory activity.",516.4,"151-73-5",100,193.65,100,193.65,"http://www.selleckchem.com/products/betamethasone-sodium-phosphate.html","C22H28FO8P.2Na","Sodium phosphate","Betamethasone 21-Phosphate Disodium Salt","[Na+].[Na+].CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO[P]([O-])([O-])=O",-0.54,3,1,4]
["E0177","Hydrocortisone sodium succinate","f5","L1300-34","in 10mM DMSO","FDA, CFDA, PMDA","JP18, USP–NF 2021(Issue 2), KP Ⅹ, Ph.Int_6th, IP2010","085492","Cancer","Glucocorticoid Receptor,Interleukins","Immunology & Inflammation","Hydrocortisone sodium succinate (Hydrocortisone 21-hemisuccinate sodium salt) has significant inhibitory effects on the IL-6 bioactivity with IC50 of 6.7 μM. Hydrocortisone sodium succinate can bind to glucocorticoid receptor, initiating the transcription of anti-inflammatory and immunosuppressive mediators.",484.51,"125-04-2",97,200.2,97,200.2,"http://www.selleckchem.com/products/hydrocortisone-sodium-succinate.html","C25H33O8.Na","Sodium succinate","Hydrocortisone 21-hemisuccinate sodium salt","[Na+].CC12CCC(=O)C=C1CCC3C4CCC(O)(C(=O)COC(=O)CCC([O-])=O)C4(C)CC(O)C23",0.03,4,1,7]
["E0181","Zinc acetate dihydrate","g5","L1300-34","in 10mM DMSO","FDA, CFDA, PMDA, NDC","USP–NF 2021(Issue 2), EP10.5","020458","Others","Others","Others","Zinc acetate dihydrate (Acetic acid zinc salt dihydrate, Dicarbomethoxyzinc dihydrate) contributes to the antiviral activity of microbicide gel through zinc targeting the reverse transcriptase.",219.51,"5970-45-6",44,200.45,44,200.45,"http://www.selleckchem.com/products/zinc-acetate-dihydrate.html","C4H10O6Zn","Dihydrate","Acetic acid zinc salt dihydrate, Dicarbomethoxyzinc dihydrate","O.O.[Zn++].CC([O-])=O.CC([O-])=O",-3.77,0,0,0]
["E0183","Magnesium chloride","h5","L1300-34","in 10mM DMSO","FDA, CFDA, PMDA, NDC","USP–NF 2021(Issue 2), EP10.5, KP Ⅹ, JP17, IP2010","089449","Others","Others","Others","Magnesium chloride can reduce the activated thromboplastin times.",95.21,"7786-30-3",10,105.03,19,199.56,"http://www.selleckchem.com/products/magnesium-chloride.html","Cl2Mg","Free Base","N/A","[Mg++].[Cl-].[Cl-]",-5.35,0,0,0]
["E0361","Enclomiphene Citrate","a6","L1300-34","in 10mM DMSO","EMA",null,null,"Others","Estrogen/progestogen Receptor","Endocrinology & Hormones","Enclomiphene citrate is the trans isomer of clomiphene citrate and acts as a non-steroidal estrogen receptor antagonist.",598.08,"7599-79-3",100,167.2,"<1",0,"http://www.selleckchem.com/products/enclomiphene-citrate.html","C26H28ClNO.C6H8O7","Citrate","N/A","CCN(CC)CCOC1=CC=C(C=C1)\\C(=C(\\Cl)C2=CC=CC=C2)C3=CC=CC=C3.OC(=O)CC(O)(CC(O)=O)C(O)=O",2.86,4,0,14]
["E1002","Setmelanotide (RM-493)","b6","L1300-34","in 10mM DMSO","FDA, EMA",null,"213793","Metabolic Disease","Melanocortin Receptor","GPCR & G Protein","Setmelanotide (RM-493, BIM-22493, CAM 4072) is a cyclic peptide full agonist of melanocortin-4 receptor (MC4R) with an EC50 of 0.27 nM and a Ki of 2.1 nM.",1117.31,"920014-72-8",100,89.5,100,89.5,"http://www.selleckchem.com/products/setmelanotide-rm-493.html","C49H68N18O9S2","Free Base","BIM-22493, CAM 4072","CC1NC(=O)C(CSSCC(NC(=O)C(CC2=C[NH]C3=CC=CC=C23)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CN=C[NH]5)NC1=O)C(N)=O)NC(=O)C(CCCN=C(N)N)NC(C)=O",-2.64,12,15,18]
["E1029","Miglustat","c6","L1300-34","in 10mM DMSO","FDA, EMA, HMA, PMDA, NDC",null,"208342","Metabolic Disease","Transferase","Metabolism","Miglustat (Zavesca, N‐butyldeoxynojirimycin, OGT 918) is an orally administered ceramide glucosyltransferase inhibitor which prevents the lysosomal accumulation of glucocerebroside.",219.28,"72599-27-0",44,200.66,44,200.66,"http://www.selleckchem.com/products/miglustat.html","C10H21NO4","Free Base","Zavesca, N‐butyldeoxynojirimycin, OGT 918","CCCCN1CC(O)C(O)C(O)C1CO",-0.58,0,4,4]
["P1092","Abaloparatide (BA058)","d6","L1300-34","in 10mM DMSO","FDA, EMA",null,"208743","Metabolic Disease","Parathyroid Hormone Receptor","GPCR & G Protein","Abaloparatide (BA058, BIM-44058, ITM-058) is a novel 34-amino acid peptide selected to be a potent and selective activator of the parathyroid hormone receptor (PTH1R) signaling pathway with an IC50 of 0.117 nM in SOST analysis.",4020.71,"247062-33-5 (acetate)",80,19.9,80,19.9,"http://www.selleckchem.com/products/abaloparatide-ba058.html","C176H304N56O51","Free Base","BIM-44058, ITM-058","N/A","N/A","N/A","N/A","N/A"]
["S0846","Euquinine","f6","L1300-34","in 10mM DMSO",null,"ChP11465",null,"Others","Anti-infection","Microbiology","Euquinine is generally used as a febrifuge, antimalarial, and tonic.",396.48,"83-75-0",79,199.25,"<1",0,"http://www.selleckchem.com/products/euquinine.html","C23H28N2O4","free base","N/A","CCOC(=O)OC(C1CC2CCN1CC2C=C)C3=C4C=C(OC)C=CC4=NC=C3",4.104,5,0,8]
["S2089","Fenoldopam","g6","L1300-34","in 10mM DMSO","FDA","USP43-NF38","076582,076656,077155,077826","Cardiovascular Disease","Dopamine Receptor","Neuronal Signaling","Fenoldopam (SKF 82526) is a selective dopamine-1 (DA1) receptor agonist with natriuretic/diuretic properties with EC50 of 55.5 nM in stimulating cAMP accumulation in LLC-PK1 cells, which is more potent than DA .",305.76,"67227-56-9",77,251.83,10,32.71,"http://www.selleckchem.com/products/fenoldopam-corlopam.html","C16H16ClNO3","free base","SKF 82526","OC1=CC=C(C=C1)C2CNCCC3=C(Cl)C(=C(O)C=C23)O",3.053,0,4,1]
["S2174","Hydroxyflutamide (Hydroxyniphtholide)","h6","L1300-34","in 10mM DMSO","FDA",null,null,"Cancer","Adrenergic Receptor","Endocrinology & Hormones","Hydroxyflutamide (SCH-16423, Hydroxyniphtholide) is an androgen receptor (AR) antagonist and possesses an IC50 of 0.7 μM for the androgen receptor.",292.21,"52806-53-8",58,198.49,"<1",0,"http://www.selleckchem.com/products/hydroxyflutamide-sch-16423-hydroxyniphtholide.html","C11H11F3N2O4","free base","Hydroxy-flutamide, SCH-16423","CC(C)(O)C(=O)NC1=CC=C(C(=C1)C(F)(F)F)[N+]([O-])=O",1.91,1,1,4]
["S3561","DLinDMA","a7","L1300-34","in 10mM DMSO","DMF",null,null,"Others","Others","Others","DLinDMA (1,2-dilinoleyloxy-N,N-dimethyl-3-aminopropane) is a key component to facilitate endosomal escape through membrane fusion between the SNALP and the endosomal membranes.",616.06,"871258-12-7","The physical form of the compound is liquid, which can be dissolved in any proportion","The physical form of the compound is liquid, which can be dissolved in any proportion",0,0,"http://www.selleckchem.com/products/dlindma.html","C41H77NO2","free base","N/A","CCCCC/C=C\\C\\C=C/CCCCCCCCOCC(CN(C)C)OCCCCCCCC\\C=C/C/C=C\\CCCCC",16.675,2,0,35]
["S3562","Deserpidine","b7","L1300-34","in 10mM DMSO","FDA,CFDA,DMF",null,"010796,012148,012775","Cardiovascular Disease","ACE","Endocrinology & Hormones","Deserpidine (Harmonyl), an alkaloid isolated from the roots of Rauwolfia canescens, is a competitive angiotensin converting enzyme (ACE) inhibitor, also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex.",578.65,"131-01-1",100,172.82,"<1",0,"http://www.selleckchem.com/products/deserpidine.html","C32H38N2O8","free base","Harmonyl","COC1C(CC2CN3CCC4=C([NH]C5=CC=CC=C45)C3CC2C1C(=O)OC)OC(=O)C6=CC(=C(OC)C(=C6)OC)OC",4.258,8,1,9]
["S5894","Mirodenafil Dihydrochloride","c7","L1300-34","in 10mM DMSO","DMF",null,null,"Angiology/Endocrinology","PDE","Metabolism","Mirodenafil Dihydrochloride(SK-3530 dihydrochloride) is an oral phosphodiesterase type 5 (PDE-5) inhibitor used to treat erectile dysfunction (ED).",604.59,"862189-96-6",100,165.4,1,1.65,"http://www.selleckchem.com/products/mirodenafil-dihydrochloride.html","C26H37N5O5S.2ClH","Dihydrochloride","SK-3530 dihydrochloride","Cl.Cl.CCCOC1=C(C=C(C=C1)[S;v6](=O)(=O)N2CCN(CCO)CC2)C3=NC(=O)C4=C(N3)C(=C[N]4CC)CCC",3.987,5,2,11]
["S6458","Isavuconazonium sulfate","d7","L1300-34","in 10mM DMSO","FDA,EMA,DMF",null,"207500,207501","Respiratory Disease","Anti-infection","Microbiology","Isavuconazonium sulfate (BAL8557-002), the prodrug of the active triazole Isavuconazole, is an orally active antifungal agent, using for invasive aspergillosis and mucormycosis.",814.84,"946075-13-4",100,122.72,100,122.72,"http://www.selleckchem.com/products/isavuconazonium-sulfate.html","C35H35F2N8O5S.HO4S","sulfate","BAL8557-002","CNCC(=O)OCC1=C(N=CC=C1)N(C)C(=O)OC(C)[N+]2=C[N](CC(O)(C(C)C3=NC(=CS3)C4=CC=C(C=C4)C#N)C5=C(F)C=CC(=C5)F)N=C2.O[S]([O-])(=O)=O",2.963,7,1,15]
["S9973","Flumatinib (HH-GV-678)","e7","L1300-34","in 10mM DMSO","CFDA",null,null,"Cancer","Bcr-Abl,c-Kit,PDGFR","Angiogenesis","Flumatinib (HH-GV-678) is a novel inhibitor of Bcr-Abl with IC50 values of 1.2  nM, 307.6  nM and 665.5  nM for c-Abl, PDGFRβand c-Kit, respectively.",562.59,"895519-90-1",100,177.75,"<1",0,"http://www.selleckchem.com/products/flumatinib-hh-gv-678.html","C29H29F3N8O","free base","HH-GV678","CN1CCN(CC1)CC2=CC=C(C=C2C(F)(F)F)C(=O)NC3=CN=C(C)C(=C3)NC4=NC(=CC=N4)C5=CN=CC=C5",3.808,5,2,8]
["E0125","Raclopride","f7","L1300-34","in 10mM DMSO",null,"USP36-NF31,EP10.0",null,"Neurological Disease","Dopamine Receptor","Neuronal Signaling","Raclopride is a selective dopamine D2/D3 receptor antagonist that discriminates between dopamine-mediated motor functions. Raclopride binds to D2 and D3 receptors with dissociation constants of between 1.8 nM and 3.5 nM, but has a very low affinity for D4 receptors.",347.24,"84225-95-6",69,198.71,1,2.88,"http://www.selleckchem.com/products/raclopride.html","C15H20Cl2N2O3","free base",0,"CCN1CCCC1CNC(=O)C2=C(OC)C(=CC(=C2O)Cl)Cl",3.085,2,2,5]
["E0190","Invert sugar","g7","L1300-34","in 10mM DMSO","CFDA","USP38-NF33,IP2010",null,"Metabolic Disease/Nutritional support","Others","Others","Invert Sugar is a popular sweetener.",360.31,"8013-17-0","The physical form of the compound is liquid, which can be dissolved in any proportion","The physical form of the compound is liquid, which can be dissolved in any proportion",0,0,"http://www.selleckchem.com/products/invert-sugar.html","C12H24O12","free base","N/A","OCC(O)C(O)C(O)C(O)C=O.OCC(O)C(O)C(O)C(=O)CO",-5.664,2,10,10]
["E0191","DL-α-tocopherol acetate","h7","L1300-34","in 10mM DMSO","CFDA","EP10.5",null,"Nutritional support","Others","Others","DL-α-Tocopherol acetate (DL-Alpha-tocopherol acetate , Vitamin E acetate), a vitamin E derivative, is used as a vitamin E supplement in poultry feeds.",472.74,"52225-20-4","The physical form of the compound is liquid, which can be dissolved in any proportion","The physical form of the compound is liquid, which can be dissolved in any proportion",0,0,"http://www.selleckchem.com/products/dl-alpha-tocopherol-acetate.html","C31H52O3","free base","DL-Alpha-tocopherol acetate, Vitamin E acetate","CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=C(C)C(=C(C)C(=C2O1)C)OC(C)=O",10.45,3,0,14]
["E0193","Mometasone Furoate Hydrate","a8","L1300-34","in 10mM DMSO","FDA,EMA,CFDA,PMDA,HMA,DMF","USP36-NF31,IP2010,EP9.1,","205641,021067,022518,211746,215712","Respiratory Disease","Immunology & Inflammation related","Immunology & Inflammation","Mometasone Furoate (SCH 32088) Hydrate is a synthetic glucocorticoid with anti-inflammatory activity.",633.51,"141646-00-6",100,157.85,"<1",0,"http://www.selleckchem.com/products/mometasone-furoate-hydrate.html","C27H30Cl2O6.H2O","Monohydrate","SCH 32088 hydrate","O.CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(Cl)C(CC2(C)C1(OC(=O)C5=CC=CO5)C(=O)CCl)OC(=O)C6=CC=CO6",5.847,8,0,8]
["E0245","Rhamnose","b8","L1300-34","in 10mM DMSO","DMF","EP10.8",null,"Gastroenterology/Inflammation","Others","Others","Rhamnose(L-Rhamnose) is an important 6-deoxy sugar present in many natural products, glycoproteins, and structural polysaccharides.",164.16,"3615-41-6",33,201.02,-1,-6.09,"http://www.selleckchem.com/products/rhamnose.html","C6H12O5","free base","L-Rhamnose","CC(O)C(O)C(O)C(O)C=O",-1.903,1,4,4]
["E0423","(R)-Avanafil","c8","L1300-34","in 10mM DMSO","FDA,EMA,CFDA,DMF",null,"202276","Angiology/Endocrinology","PDE","Metabolism","R-Avanafil is a strong competitive inhibitor of phosphodiesterase 5 (PDE5) with a demonstrated in vitro IC 50 of 5.2 nM.",483.95,"1638497-26-3",48,99.18,"<1",0,"http://www.selleckchem.com/products/r-avanafil.html","C23H26ClN7O3","free base","N/A","COC1=C(Cl)C=C(CNC2=NC(=NC=C2C(=O)NCC3=NC=CC=N3)N4CCCC4CO)C=C1",2.165,6,3,9]
["E0502","Metrizoic acid","d8","L1300-34","in 10mM DMSO","FDA",null,"017506","Diagnosis","Others","Others","Metrizoic acid(Metrizoate) is a diagnostic radiopaque. The mechanism of action of metrizoic acid is as a X-Ray contrast activity.",627.94,"1949-45-7",100,159.25,"<1",0,"http://www.selleckchem.com/products/metrizoic-acid.html","C12H11I3N2O4","free base","Metrizoate","CN(C(C)=O)C1=C(I)C(=C(I)C(=C1I)NC(C)=O)C(O)=O",1.641,3,1,3]
["E0527","Norgestimate","f8","L1300-34","in 10mM DMSO","FDA,CFDA,NDC,DMF","USP–NF 2021,EP10.8","090794,076812,205449,090523","Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity.",369.5,"35189-28-7",74,200.27,"<1",0,"http://www.selleckchem.com/products/norgestimate.html","C23H31NO3","free base",0,"CCC12CCC3C(CCC4=C/C(CCC34)=N/O)C1CCC2(OC(C)=O)C#C",5.218,3,0,3]
["E0528","Flecainide","g8","L1300-34","in 10mM DMSO","FDA,PMDA,NDC,DMF","USP43-NF38,EP8.8,JP16","210683,202821,079164,076421","Cardiovascular Disease","Others","Neuronal Signaling","Flecainide is a common medication used to help restore and maintain sinus rhythm in patients with atrial fibrillation.",414.34,"54143-55-4",83,200.32,"<1",0,"http://www.selleckchem.com/products/flecainide.html","C17H20F6N2O3","free base",0,"FC(F)(F)COC1=CC=C(OCC(F)(F)F)C(=C1)C(=O)NCC2CCCCN2",3.568,3,2,9]
["E0529","Metipranolol","h8","L1300-34","in 10mM DMSO","FDA,DMF","ChP37320","075720,019907","Ophthalmology","Adrenergic Receptor","Neuronal Signaling","Metipranolol (Betamann) is a potent β-adrenergic receptor antagonist, possessing the beta-blocking potencies (pA2) of 8.3, 8.4 at guinea pig atrial β1-adrenoceptor and β2-adrenoceptor of the rat uterus, respectively, also is a potent displacer of 3H-DHA binding, ligand concentration 0.7 nM, possessing a Ki value of 39 ± 24 nM.",309.4,"22664-55-7",62,200.39,"<1",0,"http://www.selleckchem.com/products/metipranolol.html","C17H27NO4","free base","Betamann","CC(C)NCC(O)COC1=CC(=C(OC(C)=O)C(=C1C)C)C",2.858,3,2,8]
["E0530","Prednicarbate","a9","L1300-34","in 10mM DMSO","FDA,NDC,DMF","USP43-NF38,EP10.8","019568,020279,077236,07728","Others","Others","Endocrinology & Hormones","Prednicarbate (Dermatop) is a medium potency topical corticosteroid used to manage pruritus and inflammation associated with responsive skin conditions.",488.57,"73771-04-7",98,200.59,"<1",0,"http://www.selleckchem.com/products/prednicarbate.html","C27H36O8","free base","Dermatop","CCOC(=O)OC1(CCC2C3CCC4=CC(=O)C=CC4(C)C3C(O)CC12C)C(=O)COC(=O)CC",3.677,7,1,9]
["E0609","Methyl methanesulfonate","b9","L1300-34","in 10mM DMSO",null,"EP10.8",null,"Others","DNA alkylator","DNA Damage/DNA Repair","Methyl methanesulfonate (MMS), a DNA alkylating agent, modifies both guanine (to 7-methylguanine) and adenine (to 3-methlyladenine) to cause base mispairing and replication blocks, respectively.",110.13,"66-27-3","The physical form of the compound is liquid, which can be dissolved in any proportion","The physical form of the compound is liquid, which can be dissolved in any proportion",0,0,"http://www.selleckchem.com/products/methyl-methanesulfonate.html","C2H6O3S","free base","MMS","CO[S](C)(=O)=O",-0.375,1,0,1]
["E0650","γ-Terpinene","c9","L1300-34","in 10mM DMSO",null,"EP10.8",null,"Others","Antioxidant","Apoptosis","γ-Terpinene (γ-TPN), a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly.,",136.23,"99-85-4","The physical form of the compound is liquid, which can be dissolved in any proportion","The physical form of the compound is liquid, which can be dissolved in any proportion",0,0,"http://www.selleckchem.com/products/gamma-terpinen.html","C10H16","free base","γ-TPN","CC(C)C1=CCC(=CC1)C",3.448,0,0,1]
["E0704","Esaxerenone (CS-3150)","d9","L1300-34","in 10mM DMSO","PMDA",null,null,"Cardiovascular Disease","Mineralocorticoid Receptor","Endocrinology & Hormones","Esaxerenone (CS-3150), a selective nonsteroidal mineralocorticoid receptor (MR) antagonist, binds to mineralocorticoid receptor and inhibits (3)H-aldosterone binding to mineralocorticoid receptor with an IC50 value of 9.4 nM. Esaxerenone (CS-3150) also has the property of increasing the likelihood of albuminuria returning to normal levels and reducing progression of albuminuria to higher levels.",466.48,"1632006-28-0",93,199.37,-1,-2.14,"http://www.selleckchem.com/products/esaxerenone.html","C22H21F3N2O4S","free base",0,"CC1=C([N](CCO)C=C1C(=O)NC2=CC=C(C=C2)[S](C)(=O)=O)C3=CC=CC=C3C(F)(F)F",4.139,3,2,7]
["E0706","Gemifloxacin mesylate","e9","L1300-34","in 10mM DMSO","FDA,CFDA,DMF","USP–NF 2021,IP2010","090466,021158","Respiratory Disease/Infection","Antibiotics","Microbiology","Gemifloxacin mesylate (SB265805 mesylate; LB20304 mesylate) is a novel fluoronaphthyridone with a broad spectrum of antimicrobial activity and enhances activity against gram-positive aerobes.",485.49,"210353-53-0",97,199.8,97,199.8,"http://www.selleckchem.com/products/gemifloxacin-mesylate.html","C18H20FN5O4.CH4O3S","Mesylate","SB265805 mesylate; LB20304 mesylate","CO\\N=C\\1CN(CC1CN)C2=C(F)C=C3C(=O)C(=CN(C4CC4)C3=N2)C(O)=O.C[S](O)(=O)=O",-1.513,5,1,5]
["E0707","Nomegestrol Acetate","f9","L1300-34","in 10mM DMSO","EMA,HMA","EP10.8",null,"Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Nomegestrol Acetate is a potent, highly selective progestogen, which is characterized as a full agonist at the progesterone receptor, with no or minimal binding to other steroid receptors, including the androgen and glucocorticoid receptors.",370.48,"58652-20-3",74,199.74,"<1",0,"http://www.selleckchem.com/products/nomegestrol-acetate.html","C23H30O4","free base",0,"CC(=O)OC1(CCC2C3C=C(C)C4=CC(=O)CCC4C3CCC12C)C(C)=O",3.299,4,0,3]
["E0814","Masitinib mesylate","g9","L1300-34","in 10mM DMSO","EMA,DMF",null,null,"Cancer","c-Kit,FAK,FGFR,PDGFR,Src","Protein Tyrosine Kinase","Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit with IC50 of 200 nM for human recombinant c-Kit, also inhibits PDGFRα/β with IC50s of 540/800 nM, Lyn with IC50 of 510 nM for LynB, and, to a lesser extent, FGFR3 and FAK.",594.75,"1048007-93-7",100,168.14,100,168.14,"https://www.selleckchem.com/products/masitinib-mesylate.html","C28H30N6OS.CH4O3S","Mesylate","AB-1010 mesylate","CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC=C(C)C(=C3)NC4=NC(=CS4)C5=CN=CC=C5.C[S](O)(=O)=O",4.795,3,2,7]
["E0815","Rilpivirine Hydrochloride","h9","L1300-34","in 10mM DMSO","FDA,EMA,PMDA,NDC,DMF",null,"212888,210192,208452,208351,205302","Infection","Reverse Transcriptase","Microbiology","Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.",402.88,"700361-47-3",81,201.05,"<1",0,"http://www.selleckchem.com/products/rilpivirine-hydrochloride.html","C22H18N6.ClH","hydrochloride","TMC278","Cl.CC1=C(NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C(=CC(=C1)\\C=C\\C#N)C",5.791,2,2,5]
["E0816","Oritavancin Diphosphate","a10","L1300-34","in 10mM DMSO","FDA,EMA,NDC",null,"214155,206334","Infection/Inflammation","Bacterial","Microbiology","Oritavancin Diphosphate is an orally active glycopeptide antibiotic which is active against Gram-positive bacteria and also has antibacterial activity against multidrug-resistant Streptococcus pneumoniae.",1989.09,"192564-14-0",100,50.27,50,25.14,"http://www.selleckchem.com/products/oritavancin-diphosphate.html","C86H97Cl3N10O26.2H3O4P","Diphosphate","N/A","CNC(CC(C)C)C(=O)NC1C(O)C2=CC(=C(OC3=C(OC4OC(CO)C(O)C(O)C4OC5CC(C)(NCC6=CC=C(C=C6)C7=CC=C(Cl)C=C7)C(O)C(C)O5)C8=CC(=C3)C(NC(=O)C(CC(N)=O)NC1=O)C(=O)NC9C(=O)NC(C(OC%10CC(C)(N)C(O)C(C)O%10)C%11=CC(=C(O8)C=C%11)Cl)C(=O)NC(C(O)=O)C%12=C(C(=CC(=C%12)O)O)C%13=C(O)C=CC9=C%13)C=C2)Cl.O[P](O)(O)=O.O[P](O)(O)=O",0.667,16,19,19]
["E0826","Levamlodipine Besylate","b10","L1300-34","in 10mM DMSO","FDA,CFDA","ChP23161","212895","Cardiovascular Disease","Calcium Channel","Transmembrane Transporters","Levamlodipine Besylate is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina.",448.88,"150566-71-5",100,222.78,2,4.46,"http://www.selleckchem.com/products/levamlodipine-besylate.html","C20H25ClN2O5.C6H6O3S","Besylate",0,"CCOC(=O)C1=C(COCCN)NC(=C(C1C2=C(Cl)C=CC=C2)C(=O)OC)C.O[S](=O)(=O)C3=CC=CC=C3",3.473,5,2,11]
["E0937","Segesterone acetate","c10","L1300-34","in 10mM DMSO","FDA,NDC",null,209627,"Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Segesterone acetate (Nestoron, ST-1435) is a synthetic progestin that binds to the progesterone receptor with EC50 of 50.3 nM.",370.48,"7759-35-5",74,199.74,"<1",0,"http://www.selleckchem.com/products/segesterone.html","C23H30O4","free base","Nestoron, ST-1435","CC(=O)OC1(C(C)=O)C(=C)CC2C3CCC4=CC(=O)CCC4C3CCC12C",3.488,4,0,3]
["E1248","p-Nitrobenzyl mesylate","e10","L1300-34","in 10mM DMSO",null,"USP43-NF38,IP2010",null,"Others","Others","Others","p-Nitrobenzyl mesylate is an alkylating reagent for direct kinase substrate identification.",231.23,"39628-94-9",46,198.94,"<1",0,"http://www.selleckchem.com/products/p-nitrobenzyl-mesylate.html","C8H9NO5S","free base",0,"C[S;v6](=O)(=O)OCC1=CC=C(C=C1)[N;v5](=O)=O",1.103,1,0,4]
["E2355","Dotinurad","f10","L1300-34","in 10mM DMSO","PMDA",null,null,"Cardiovascular Disease","OAT","Transmembrane Transporters","Dotinurad (FYU-981), a selective urate reabsorption inhibitor (SURI), potently inhibits urate transporter 1 (URAT1) with IC50 of 37.2 nM.",358.2,"1285572-51-1",72,201.01,"<1",0,"http://www.selleckchem.com/products/dotinurad.html","C14H9Cl2NO4S","free base","FYU-981","OC1=C(Cl)C=C(C=C1Cl)C(=O)N2C[S;v6](=O)(=O)C3=CC=CC=C23",3.234,3,1,1]
["E2356","Tandospirone","g10","L1300-34","in 10mM DMSO","CFDA,PMDA","ChP23330",null,"Neurological Disease","5-HT Receptor","Neuronal Signaling","Tandospirone (SM-3997), a potent and selective 5-HT1A receptor partial agonist, with a Ki of 27 nM, has anxiolytic and antidepressant activities.",383.49,"87760-53-0",26,67.8,"<1",0,"http://www.selleckchem.com/products/tandospirone.html","C21H29N5O2","free base","SM-3997","O=C1C2C3CCC(C3)C2C(=O)N1CCCCN4CCN(CC4)C5=NC=CC=N5",1.707,4,0,6]
["E2358","Azosemide","h10","L1300-34","in 10mM DMSO","PMDA","JP18",null,"Cardiovascular Disease","NKCC","Transmembrane Transporters","Azosemide is a potent Na+–K+–2Cl− cotransporter NKCC1 inhibitor with IC50s of 0.246 µM for hNKCC1A and 0.197 µM for NKCC1B, respectively.",370.84,"27589-33-9",74,199.55,"<1",0,"http://www.selleckchem.com/products/azosemide.html","C12H11ClN6O2S2","free base",0,"N[S](=O)(=O)C1=CC(=C(NCC2=CC=CS2)C=C1Cl)C3=N[NH]N=N3",1.801,5,3,5]
["E2516","Doxorubicin","a11","L1300-34","in 10mM DMSO","FDA,CFDA,EMA,HMA,NDC,DMF","USP40-NF35,EP9.1,JP18","212299,209825,208888,208657","Cancer","Topoisomerase","DNA Damage/DNA Repair","Adriamycin (Doxorubicin, Hydroxydaunorubicin), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent, inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DNA replication, and induces apoptosis, also inhibits human DNA topoisomerase I with an IC50 of 0.8 μM.",543.52,"23214-92-8",100,183.99,50,91.99,"http://www.selleckchem.com/products/doxorubicin.html","C27H29NO11","free base","Adriamycin,Hydroxydaunorubicin","COC1=C2C(=O)C3=C(C(=C4CC(O)(CC(OC5CC(N)C(O)C(C)O5)C4=C3O)C(=O)CO)O)C(=O)C2=CC=C1",-0.044,6,5,5]
["E2634","H-Leu-Leu-OMe Hydrochloride","b11","L1300-34","in 10mM DMSO","DMF",null,null,"Others","Immunology & Inflammation related","Immunology & Inflammation","H-Leu-Leu-OMe Hydrochloride (H-LEU-LEU-OME HCL), a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential, also can induce endolysosomal pathway stress.",294.82,"6491-83-4",71,240.82,"<1",0,"http://www.selleckchem.com/products/h-leu-leu-ome-hydrochloride.html","C13H26N2O3.ClH","hydrochloride","H-LEU-LEU-OME HCL","Cl.COC(=O)C(CC(C)C)NC(=O)C(N)CC(C)C",1.933,3,2,8]
["E2683","Ursodeoxycholic acid sodium","c11","L1300-34","in 10mM DMSO","CFDA,PMDA,DMF","USP38-NF33,JP16,EP8.8",null,"Metabolic Disease","Others","Others","Ursodeoxycholic acid sodium is a sodium salt of a naturally occurring bile acid that is used to treat a variety of hepatic and gastrointestinal diseases.",414.55,"2898-95-5",83,200.22,83,200.22,"http://www.selleckchem.com/products/ursodeoxycholic-acid-sodium.html","C24H40O4.Na","Sodium salt",0,"[Na+].CC(CCC([O-])=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C",2.54,0,2,4]
["E2690","3,3'-Diaminobenzidine tetrahydrochloride","d11","L1300-34","in 10mM DMSO",null,"EP10.8",null,"Others","Dyes","Others","3,3'-Diaminobenzidine tetrahydrochloride (DAB) is the most sensitive and commonly used substrate for horseradish peroxidase, which can visualize the color of cells or tissues bound by horseradish peroxidase during immunohistochemistry or in situ hybridization.",378.13,"868272-85-9",54,142.81,54,142.81,"http://www.selleckchem.com/products/3-3--diaminobenzidine-tetrahydrochloride.html","C12H14N4.4ClH.H2O","Tetrahydrochloride Monohydride","DAB","O.Cl.Cl.Cl.Cl.NC1=C(N)C=C(C=C1)C2=CC(=C(N)C=C2)N",1.682,0,4,1]
["E2826","Hematein","e11","L1300-34","in 10mM DMSO",null,"USP42-NF37",null,"Cancer","Akt,Casein Kinase","Metabolism","Hematein inhibits casein kinase II activity in a selective, dose-dependent and ATP non-competitive manner in vitro, with IC50 of 0.55 μM in the presence of 10 μM ATP.",300.26,"475-25-2",60,199.83,"<1",0,"http://www.selleckchem.com/products/hematein.html","C16H12O6","free base",0,"OC1=CC2=C(C=C1O)C3=C4C=CC(=O)C(=C4OCC3(O)C2)O",0.558,2,3,0]
["P1008","Carbetocin Acetate","f11","L1300-34","in 10mM DMSO","CFDA","ChP37776",null,"Angiology","Oxytocin receptor","Endocrinology & Hormones","Carbetocin Acetate is a long-acting oxytocin-analogue and a potent agonist of the oxytocin receptor (OXTR), with improved in vivo stability over oxytocin.",988.16,"37025-55-1",100,101.2,100,101.2,"http://www.selleckchem.com/peptide/carbetocin-acetate.html","C45H69N11O12S","Acetate",0,"CCC(C)C1NC(=O)C(CC2=CC=C(OC)C=C2)NC(=O)CCCSCC(NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC1=O)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(N)=O.CC(O)=O",-1.699,13,10,18]
["P1108","Bremelanotide Acetate","g11","L1300-34","in 10mM DMSO","FDA",null,"210557","Endocrinology","Melanocortin Receptor","Endocrinology & Hormones","Bremelanotide Acetate (PT-141 Acetate) is a melanocortin receptor (MCR) agonist recently approved in the USA for the treatment of premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD), as characterized by low sexual desire that causes marked distress or interpersonal difficulty.",1085.22,"1607799-13-2",100,92.15,100,92.15,"http://www.selleckchem.com/products/bremelanotide-acetate.html","C50H68N14O10.C2H4O2","Acetate","PT141 Acetate","CCCCC(NC(C)=O)C(=O)NC1CC(=O)NCCCCC(NC(=O)C(CC2=C[NH]C3=CC=CC=C23)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CN=C[NH]5)NC1=O)C(O)=O.CC(O)=O",0.28,12,12,17]
["P1110","Etelcalcetide HCl","h11","L1300-34","in 10mM DMSO","FDA,EMA,infor",null,"208325","Endocrinology","CaSR","GPCR & G Protein","Etelcalcetide HCl (AMG 416) is a novel synthetic peptide agonist of the calcium-sensing receptor (CaSR) composed of a linear chain of seven d-amino acids with a d-cysteine linked to an l-cysteine via a disulfide bond.",1084.71,"1334237-71-6",100,92.19,100,92.19,"http://www.selleckchem.com/products/etelcalcetide-hcl.html","C38H74ClN21O10S2","hydrochloride","AMG 416","Cl.CC(NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(C)NC(=O)C(CC(S)C(N)(S)C(O)=O)NC(C)=O)C(=O)NC(CCCN=C(N)N)C(N)=O",-9.149,13,17,34]
["P1114","Dasiglucagon","a2","L1300-35","in 10mM DMSO","FDA,NDC",null,"214231","Metabolic Disease","Others","Metabolism","Dasiglucagon, a stable peptide analog of human glucagon, is a fast and effective treatment option for severe hypoglycemia.",3381.62,"1544300-84-6",100,29.57,100,29.57,"http://www.selleckchem.com/products/dasiglucagon.html","C152H222N38O50","free base",0,"CC(C)CC(NC(=O)C(CC1=C[NH]C2=CC=CC=C12)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C)NC(=O)C(CCCNC(N)=N)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C(CC(O)=O)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=C(O)C=C4)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC5=CC=C(O)C=C5)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(NC(=O)C(CC6=CC=CC=C6)NC(=O)C(NC(=O)CNC(=O)C(CCC(N)=O)NC(=O)C(CO)NC(=O)C(N)CC7=CN=C[NH]7)C(C)O)C(C)O)C(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CO)C(=O)NC(C(C)O)C(O)=O",-19.686,36,45,110]
["S1469","Calcifediol","c2","L1300-35","in 10mM DMSO","FDA,DMF","USPNF 2022 Issue 1,EP10.8,Chp52287","018312,208010","Endocrinology","Vitamin","Metabolism","Calcifediol (Calcidiol, Didrogyl, Hidroferol, 25-hydroxyvitamin D3, 25-Hydroxycholecalciferol) is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It also suppresses PTH secretion and mRNA (ED50=2 nM).",400.64,"19356-17-3",80,199.68,"<1",0,"http://www.selleckchem.com/products/Calcifediol.html","C27H44O2","free base","Calcidiol, Didrogyl, Hidroferol, 25-hydroxyvitamin D3, 25-Hydroxycholecalciferol","CC(CCCC(C)(C)O)C1CCC2/C(CCCC12C)=C/C=C3/CC(O)CCC3=C",6.404,0,1,6]
["S7048","Talazoparib (BMN 673)","d2","L1300-35","in 10mM DMSO","FDA,EMA",null,211651,"Cancer","PARP","DNA Damage/DNA Repair","Talazoparib (BMN 673, LT-673) is a novel PARP inhibitor with IC50 of 0.57 nM for PARP1 in a cell-free assay. It is also a potent inhibitor of PARP-2, but does not inhibit PARG and is highly sensitive to PTEN mutation. Phase 3.",380.35,"1207456-01-6",38,99.91,"<1",0,"http://www.selleckchem.com/products/bmn-673.html","C19H14F2N6O","free base","LT-673","C[N]1N=CN=C1C2C(NC3=CC(=CC4=C3C2=NNC4=O)F)C5=CC=C(F)C=C5",2.467,4,2,2]
["S7108","Encorafenib (LGX818)","e2","L1300-35","in 10mM DMSO","FDA,EMA,PMDA,DMF",null,210496,"Cancer","Raf","MAPK","Encorafenib (LGX818) is a highly potent RAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing B-RAF(V600E) with EC50 of 4 nM. Phase 3.",540.01,"1269440-17-6",100,185.18,"<1",0,"http://www.selleckchem.com/products/lgx818.html","C22 H27 Cl F N7 O4 S","free base","N/A","COC(=O)NC(C)CNC1=NC=CC(=N1)C2=C[N](N=C2C3=C(F)C(=CC(=C3)Cl)N[S;v6](C)(=O)=O)C(C)C",3.645,7,3,10]
["S8162","Upadacitinib (ABT-494)","f2","L1300-35","in 10mM DMSO","FDA,EMA,PMDA,DMF",null,211675,"Immunology","JAK","JAK/STAT","Upadacitinib (ABT-494) is a selective JAK1 inhibitor which demonstrates activity against JAK1 (0.045 μM) and JAK2 (0.109 μM),  with > 40 fold selectivity over JAK3 (2.1 μM) and 100 fold selectivity over TYK2 (4.7 μM) as compared to JAK1.",380.37,"1310726-60-3",76,199.81,"<1",0,"http://www.selleckchem.com/products/upadacitinib.html","C17H19F3N6O","free base","N/A","CCC1CN(CC1C2=CN=C3C=NC4=C(C=C[NH]4)[N]23)C(=O)NCC(F)(F)F",1.967,3,2,4]
["S8553","Avapritinib (BLU-285)","g2","L1300-35","in 10mM DMSO","FDA,EMA",null,212608,"Cancer","c-Kit,PDGFR","Protein Tyrosine Kinase","Avapritinib (BLU-285) is a small molecule kinase inhibitor that potently inhibits PDGFRα D842V mutant activity in vitro (IC50 = 0.5 nM) and PDGFRα D842V autophosphorylation in the cellular setting (IC50 = 30 nM); also a potent inhibitor of the analogous Kit (c-Kit) mutation, D816V in Kit (c-Kit) Exon 17 (IC50 = 0.5 nM).",498.56,"1703793-34-3",66,132.38,"<1",0,"http://www.selleckchem.com/products/blu-285.html","C26H27FN10","free base","N/A","C[N]1C=C(C=N1)C2=C[N]3N=CN=C(N4CCN(CC4)C5=NC=C(C=N5)C(C)(N)C6=CC=C(F)C=C6)C3=C2",2.799,5,1,5]
["S8879","Deucravacitinib (BMS-986165)","h2","L1300-35","in 10mM DMSO","FDA,EMA,PMDA,NDC,CFDA",null,"005755,214958","Inflammation/Immunology","IFN,Interleukins,JAK","Protein Tyrosine Kinase","Deucravacitinib (BMS-986165) is a highly potent and selective allosteric inhibitor of Tyk2 with a Ki value of 0.02 nM for binding to the Tyk2 pseudokinase domain. It is highly selective against a panel of 265 kinases and pseudokinases.",425.46,"1609392-27-9",29,68.16,"<1",0,"http://www.selleckchem.com/products/bms-986165.html","C20H19D3N8O3","free base","N/A","C(NC(=O)C1=C(NC2=CC=CC(=C2OC)C3=N[N](C)C=N3)C=C(NC(=O)C4CC4)N=N1)([2H])([2H])[2H]",1.385,7,3,8]
["E0680","Deslanoside","a3","L1300-35","in 10mM DMSO","CFDA,PMDA","USP40-NF35,JP18,EP10.8",null,"Cardiovascular Disease","ATPase","Transmembrane Transporters","Deslanoside(Desacetyllanatoside C) is a cardenolide glycoside, has the effects of anti-arrhythmia and cardiotonic, also is used as an EC 3.6.3.9 (Na+/K+-transporting ATPase) inhibitor.",943.08,"17598-65-1",100,106.04,"<1",0,"http://www.selleckchem.com/products/deslanoside.html","C47H74O19","free base","Desacetyllanatoside C","CC1OC(CC(O)C1OC2CC(O)C(OC3CC(O)C(OC4OC(CO)C(O)C(O)C4O)C(C)O3)C(C)O2)OC5CCC6(C)C(CCC7C6CC(O)C8(C)C(CCC78O)C9=CC(=O)OC9)C5",0.252,10,8,10]
["S0803","Danicopan (ACH-4471)","b3","L1300-35","in 10mM DMSO","EMA,FDA,NDC,PMDA",null,"005517,218037 ","Inflammation/Immunology","Complement System","Immunology & Inflammation","Danicopan (ACH-4471, ACH-0144471, ACH-CFDIS, ALXN 2040) is a potent, selective and orally active inhibitor of factor D with Kd of 0.54 nM for human Factor D. Danicopan inhibits alternative pathway of complement (APC) activity, and has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).",580.41,"1903768-17-1",100,172.29,"<1",0,"http://www.selleckchem.com/products/danicopan.html","C26H23BrFN7O3","Free base","ACH-0144471, ACH-CFDIS, ALXN 2040","CC(=O)C1=N[N](CC(=O)N2CC(F)CC2C(=O)NC3=NC(=CC=C3)Br)C4=C1C=C(C=C4)C5=CN=C(C)N=C5",2.262,7,1,6]
["S0861","Laninamivir Octanoate","c3","L1300-35","in 10mM DMSO","PMDA",null,null,"Infection","Influenza Virus,Neuraminidase","Immunology & Inflammation","Laninamivir octanoate (CS-8958, R-118958, Inavir, LANI), a prodrug of Laninamivir (R-125489), is a long-acting neuraminidase (NA) inhibitor with superior anti-influenza virus activity.",472.53,"203120-46-1",95,201.05,"<1",0,"http://www.selleckchem.com/products/laninamivir-octanoate.html","C21H36N4O8","Free base","CS-8958, R-118958, Inavir, LANI","CCCCCCCC(=O)OCC(O)C(OC)C1OC(=CC(N=C(N)N)C1NC(C)=O)C(O)=O",0.34,7,4,15]
["S1217","Cyclophosphamide","d3","L1300-35","in 10mM DMSO","FDA,CFDA,PMDA,NDC,DMF","USPNF 2022 Issue 1,EP10.8,JP15","040032,088371,203856,204555,211608","Cancer","DNA/RNA Synthesis","DNA Damage/DNA Repair","Cyclophosphamide(NSC 26271,Endoxan, Cytoxan, Neosar, Procytox, Revimmune, Cytophosphane) is a nitrogen mustard alkylating agent from the oxazophorines group.",261.09,"50-18-0",52,199.17,43,164.69,"http://www.selleckchem.com/products/Clafen.html","C7H15Cl2N2O2P","Free base","NSC 26271,Endoxan, Cytoxan, Neosar, Procytox, Revimmune, Cytophosphane","ClCCN(CCCl)[P]1(=O)NCCCO1",0.144,2,1,5]
["S2221","Apatinib (YN968D1) mesylate","e3","L1300-35","in 10mM DMSO","CFDA",null,null,"Cancer","VEGFR","Protein Tyrosine Kinase","Apatinib mesylate (YN968D1, Rivoceranib) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib mesylate induces both autophagy and apoptosis.",493.58,"1218779-75-9",22,44.57,"<1",0,"http://www.selleckchem.com/products/Apatinib-YN968D1.html","C25H27N5O4S","Mesylate","YN968D1, Rivoceranib","C[S](O)(=O)=O.O=C(NC1=CC=C(C=C1)C2(CCCC2)C#N)C3=CC=CN=C3NCC4=CC=NC=C4",3.164,3,2,6]
["S2345","Podophyllotoxin (Podofilox)","f3","L1300-35","in 10mM DMSO","FDA,CFDA","EP10.8","075600,090184","Infection","5-alpha Reductase","Angiogenesis","Podophyllotoxin (Condylox,Podofilox) is a lignan (lignans) found in podophyllin resin from the roots of podophyllum plants.",414.41,"518-28-5",83,200.28,"<1",0,"http://www.selleckchem.com/products/Podophyllotoxin(Podofilox).html","C22H22O8","Free base","Condylox,Podofilox","COC1=C(OC)C(=CC(=C1)C2C3C(COC3=O)C(O)C4=CC5=C(OCO5)C=C24)OC",2.111,7,1,4]
["S3020","Romidepsin","g3","L1300-35","in 10mM DMSO","FDA,EMA,PMDA,NDC,DMF",null,"208574,206254,022393","Cancer","Apoptosis related,HDAC","Cytoskeletal Signaling","Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM in cell-free assays, respectively. Romidepsin (FK228/depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cells.",540.7,"128517-07-7",10,18.49,"<1",0,"http://www.selleckchem.com/products/Romidepsin-FK228.html","C24H36N4O6S2","Free base","FK228, Depsipeptide, FR 901228, NSC 630176,","C\\C=C1/NC(=O)C2CSSCC/C=C/C(CC(=O)NC(C(C)C)C(=O)N2)OC(=O)C(NC1=O)C(C)C",1.689,6,4,2]
["S5218","Iodixanol","h3","L1300-35","in 10mM DMSO","FDA,CFDA,PMDA,NDC,DMF","USP43-NF38,EP10.6","214271","Cardiovascular Disease","Others","Others","Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography.",1550.18,"92339-11-2",100,64.51,"<1",0,"http://www.selleckchem.com/products/iodixanol.html","C35H44I6N6O15","Free base","N/A","CC(=O)N(CC(O)CN(C(C)=O)C1=C(I)C(=C(I)C(=C1I)C(=O)NCC(O)CO)C(=O)NCC(O)CO)C2=C(I)C(=C(I)C(=C2I)C(=O)NCC(O)CO)C(=O)NCC(O)CO",-2.279,6,13,22]
["S6984","Dianhydrogalactitol (VAL-083)","b4","L1300-35","in 10mM DMSO","CFDA","ChP39160",null,"Cancer","DNA alkylator","DNA Damage/DNA Repair","Dianhydrogalactitol (VAL-083, Dianhydrodulcitol, Dulcitol Diepoxide) is a bi-functional alkylating agent that readily crosses the blood-brain barrier and creates N7 methylation on DNA. Dianhydrogalactitol shows antitumor activity.",146.14,"23261-20-3",29,198.44,29,198.44,"http://www.selleckchem.com/products/dianhydrogalactitol-val-083.html","C6H10O4","Free base","Dianhydrodulcitol, Dulcitol Diepoxide","OC(C(O)C1CO1)C2CO2",-1.408,2,2,3]
["S7930","Ixabepilone (BMS-247550)","c4","L1300-35","in 10mM DMSO","FDA,DMF","USPNF 2022 Issue 1","022065","Cancer","Microtubule Associated","Cytoskeletal Signaling","Ixabepilone (Azaepothilone B, BMS-247550, Ixempra, Aza-epothilone B) is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis.",506.7,"219989-84-1",100,197.36,"<1",0,"http://www.selleckchem.com/products/ixabepilone-bms-247550.html","C27H42N2O5S","Free base","Azaepothilone B, BMS-247550, Ixempra, Aza-epothilone B","CC1CCCC2(C)OC2CC(NC(=O)CC(O)C(C)(C)C(=O)C(C)C1O)C(/C)=C/C3=CSC(=N3)C",3.132,4,3,2]
["S8064","Midostaurin (PKC412)","d4","L1300-35","in 10mM DMSO","FDA,EMA,DMF",null,"207997","Cancer","PKC","Cytoskeletal Signaling","Midostaurin (pkc412, CGP 41251) is a multi-targeted kinase inhibitor, including PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50 ranging from 80-500 nM.",570.64,"120685-11-2",100,175.24,"<1",0,"http://www.selleckchem.com/products/midostaurin-pkc412.html","C35H30N4O4","Free base","CGP 41251","COC1C(CC2OC1(C)[N]3C4=C(C=CC=C4)C5=C3C6=C(C7=C(C=CC=C7)[N]26)C8=C5CNC8=O)N(C)C(=O)C9=CC=CC=C9",5.279,4,1,3]
["S8716","Pralsetinib (BLU-667)","e4","L1300-35","in 10mM DMSO","FDA,EMA,CFDA,NDC",null,"214701,213721","Cancer","c-RET","Apoptosis","Pralsetinib (BLU-667, CS 3009, Gavreto) is a highly potent and selective RET (c-RET) inhibitor with an IC50 of 0.4 nM for WT RET. It also demonstrates potent activity (IC50 0.4 nmol/L) against common oncogenic RET alterations, including RET (M918T).",533.6,"2097132-94-8",100,187.41,"<1",0,"http://www.selleckchem.com/products/blu-667.html","C27H32FN9O2","Free base","CS 3009, Gavreto","COC1(CCC(CC1)C2=NC(=CC(=N2)NC3=N[NH]C(=C3)C)C)C(=O)NC(C)C4=CN=C(C=C4)[N]5C=C(F)C=N5",3.716,7,3,8]
["S8830","Sotorasib (AMG510)","f4","L1300-35","in 10mM DMSO","FDA,EMA,PMDA",null,"214665","Cancer","Ras","Cell Cycle","Sotorasib (AMG510) is a potent KRAS G12C covalent inhibitor with potential antineoplastic activity.This AMG510 is a chiral compound.",560.59,"2296729-00-3",100,178.38,"<1",0,"http://www.selleckchem.com/products/amg510.html","C30H30F2N6O3","Free base","N/A","CC(C)C1=C(N2C(=O)N=C(N3CCN(CC3C)C(=O)C=C)C4=CC(=C(N=C24)C5=C(F)C=CC=C5O)F)C(=CC=N1)C",5.357,5,1,5]
["S8851","Elexacaftor (VX-445)","g4","L1300-35","in 10mM DMSO","FDA,EMA,NDC",null,"212273","Respiratory Disease;Gastroenterology","CFTR","Transmembrane Transporters","Elexacaftor (VX-445) is a next-generation cystic fibrosis transmembrane conductance regulator (CFTR) corrector.This is a compound which is not chiral purity.",597.65,"2216712-66-0",100,167.32,"<1",0,"http://www.selleckchem.com/products/elexacaftor.html","C26H34F3N7O4S","Free base","N/A","CC1CN(C2=C(C=CC(=N2)[N]3C=CC(=N3)OCC(C)(C)C(F)(F)F)C(=O)N[S](=O)(=O)C4=C[N](C)N=C4C)C(C)(C)C1",5.245,7,1,9]
["S8884","Adagrasib (MRTX849)","h4","L1300-35","in 10mM DMSO","FDA, NDC",null,216340,"Cancer","Ras","Cell Cycle","Adagrasib (MRTX849) is a potent, selective, and covalent KRASG12C inhibitor that exhibits favorable drug-like properties, selectively modifies mutant cysteine 12 in GDP-bound KRASG12C and inhibits KRAS-dependent signaling.",604.12,"2326521-71-3",100,165.53,"<1",0,"http://www.selleckchem.com/products/mrtx849.html","C32H35ClFN7O2","Free base","N/A","CN1CCCC1COC2=NC3=C(CCN(C3)C4=CC=CC5=C4C(=CC=C5)Cl)C(=N2)N6CCN(C(CC#N)C6)C(=O)C(F)=C",5.325,4,0,7]
["S8926","Valemetostat (DS-3201)","a5","L1300-35","in 10mM DMSO","PMDA",null,null,"Cancer","EZH1/2","Methylation","Valemetostat (DS-3201, DS-3201b) is a selective EZH1/2 dual inhibitor.",488.02,"1809336-39-7",100,204.91,"<1",0,"http://www.selleckchem.com/products/valemetostat-ds-3201.html","C26H34ClN3O4","Free base","DS-3201b","CN(C)C1CCC(CC1)C2(C)OC3=C(Cl)C=C(C(=O)NCC4=C(C)C=C(C)NC4=O)C(=C3O2)C",3.963,4,2,5]
["S8942","Suramin sodium salt","b5","L1300-35","in 10mM DMSO",null,"Ph.Int_6th",null,"Infection","DNA/RNA Synthesis,Sirtuin,Topoisomerase","Metabolism","Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatase (PTPases) inhibitor, also is the potent inhibitor of sirtuins, purified topoisomerase II and SARS-CoV-2 RNA-dependent RNA polymerase (RdRp).",1435.23,"129-46-4",100,69.68,100,69.68,"http://www.selleckchem.com/products/suramin-sodium-salt.html","C51H40N6O23S6.6Na","Sodium salt","Suramin hexasodium salt","CC1=C(NC(=O)C2=CC(=CC=C2)NC(=O)NC3=CC(=CC=C3)C(=O)NC4=CC(=CC=C4C)C(=O)NC5=CC=C(C6=C5C(=CC(=C6)[S;v6](=O)(=O)O[Na])[S;v6](=O)(=O)O[Na])[S;v6](=O)(=O)O[Na])C=C(C=C1)C(=O)NC7=CC=C(C8=C7C(=CC(=C8)[S;v6](=O)(=O)O[Na])[S;v6](=O)(=O)O[Na])[S;v6](=O)(=O)O[Na]",4.993,11,6,22]
["S8955","Sotorasib (AMG510) racemate","c5","L1300-35","in 10mM DMSO","FDA,EMA,PMDA",null,214665,"Cancer","Ras","Cell Cycle","Sotorasib (AMG510) racemate is a racemic of AMG-510 which is a potent KRAS G12C covalent inhibitor with potential antineoplastic activity.",560.59,"2252403-56-6",100,178.38,"<1",0,"http://www.selleckchem.com/products/amg-510-racemate.html","C30H30F2N6O3","Free base","N/A","CC(C)C1=C(N2C(=O)N=C(N3CCN(CC3C)C(=O)C=C)C4=CC(=C(N=C24)C5=C(F)C=CC=C5O)F)C(=CC=N1)C",5.357,5,1,5]
["S8999","Exatecan Mesylate","d5","L1300-35","in 10mM DMSO","DMF",null,null,"Cancer","Topoisomerase","DNA Damage/DNA Repair","Exatecan Mesylate (DX-8951f) is a water-soluble and non-pro-drug analog of camptothecin and shows significant topoisomerase I inhibition with IC50 of 0.975 μg/ml.",531.55,"169869-90-3",12.5,23.52,12.5,23.52,"http://www.selleckchem.com/products/exatecan-mesylate.html","C24H22FN3O4.CH4O3S","Mesylate","DX-8951 Mesylate","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C5C(N)CCC6=C5C(=CC(=C6C)F)N=C34)C2=O.C[S](O)(=O)=O",1.689,4,1,1]
["S9522","Valrubicin","e5","L1300-35","in 10mM DMSO","FDA,NDC,DMF","USP43-NF38","206430,020892","Cancer","PKC","TGF-beta/Smad","Valrubicin(AD-32) is a chemotherapy drug used to treat bladder cancer. Valrubicin is a chemotherapy agent, inhibits TPA- and PDBu-induced PKC activation with IC50s of 0.85 and 1.25 μM, respectively.",723.64,"56124-62-0",100,138.19,"<1",0,"http://www.selleckchem.com/products/valrubicin.html","C34H36F3NO13","Free base","AD-32","CCCCC(=O)OCC(=O)C1(O)CC(OC2CC(NC(=O)C(F)(F)F)C(O)C(C)O2)C3=C(C1)C(=C4C(=O)C5=C(C(=O)C4=C3O)C(=CC=C5)OC)O",3.024,9,4,12]
["S9702","Finerenone","f5","L1300-35","in 10mM DMSO","FDA,EMA,PMDA,NDC",null,"215341","Metabolic Disease","Mineralocorticoid Receptor","Endocrinology & Hormones","Finerenone (FIN, BAY 94-8862) is a highly selective and orally available nonsteroidal antagonist of mineralocorticoid receptor (MR) with IC50 of 18 nM. Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.",378.42,"1050477-31-0",76,200.84,"<1",0,"http://www.selleckchem.com/products/finerenone.html","C21H22N4O3","Free base","FIN, BAY 94-8862","CCOC1=NC=C(C)C2=C1C(C3=CC=C(C=C3OC)C#N)C(=C(C)N2)C(N)=O",2.613,4,2,5]
["S9726","Rimiducid (AP1903)","g5","L1300-35","in 10mM DMSO","DMF",null,null,"Cancer","FKBP","Apoptosis","Rimiducid (AP1903) is a chemical protein dimerizer and binds tightly to the target FKBP fusion protein while binding minimally to the abundant natural FKBP. Rimiducid elicites potent and dose-dependent apoptosis of cells in culture expressing dimerizer-dependent Fas constructs, with an EC50 of ≈0.1 nM.",1411.63,"195514-63-7",100,70.84,"<1",0,"http://www.selleckchem.com/products/rimiducid-ap1903.html","C78H98N4O20","Free base","N/A","CCC(C(=O)N1CCCCC1C(=O)OC(CCC2=CC(=C(OC)C=C2)OC)C3=CC(=CC=C3)OCC(=O)NCCNC(=O)COC4=CC=CC(=C4)C(CCC5=CC(=C(OC)C=C5)OC)OC(=O)C6CCCCN6C(=O)C(CC)C7=CC(=C(OC)C(=C7)OC)OC)C8=CC(=C(OC)C(=C8)OC)OC",11.602,20,2,39]
["S9825","Pirtobrutinib (LOXO-305)","h5","L1300-35","in 10mM DMSO","EMA,FDA,NDC,PMDA,CFDA",null,"005863,216059 ","Cancer","BTK","Angiogenesis","Pirtobrutinib (LOXO-305, LY 3527727, RXC-005) is a highly selective, non-covalent, next generation BTK inhibitor with an IC50 of 5.69 nM in WT BTK HEK cells. Pirtobrutinib shows more than 300-fold selective for BTK over 98% of 370 other kinases.",479.43,"2101700-15-4",96,200.24,"<1",0,"http://www.selleckchem.com/products/pirtobrutinib-loxo-305.html","C22H21F4N5O3","Free base","LY 3527727, RXC-005","COC1=CC=C(F)C=C1C(=O)NCC2=CC=C(C=C2)C3=N[N](C(C)C(F)(F)F)C(=C3C(N)=O)N",3.172,4,3,8]
["S9866","Nirmatrelvir (PF-07321332)","a6","L1300-35","in 10mM DMSO","CFDA,NDC",null,null,"Infection","COVID-19,SARS-CoV","Microbiology","Nirmatrelvir (PF-07321332) is an reversible covalent inhibitor of SARS-CoV-2 main protease (Mpro, also referred to as 3CL protease) with an ki of 3.11 nM. PF-07321332 binds directly to the catalytic cysteine (Cys145) residue of the enzyme.",499.53,"2628280-40-8",100,200.19,2,4,"http://www.selleckchem.com/products/pf-07321332.html","C23H32F3N5O4","Free base","N/A","CC(C)(C)C(NC(=O)C(F)(F)F)C(=O)N1CC2C(C1C(=O)NC(CC3CCNC3=O)C#N)C2(C)C",0.799,4,3,8]
["E0164","Antazoline Phosphate","b6","L1300-35","in 10mM DMSO","FDA,CFDA","USPNF 2022 Issue 1,EP10.8","018746","Inflammation;Ophthalmology","Histamine Receptor","Neuronal Signaling","Antazoline Phosphate is the phosphate salt of antazoline. Antazoline is a first-generation antihistaminic agent and acts as a histamine H1 receptor antagonist.",363.35,"154-68-7",18,49.54,73,200.91,"http://www.selleckchem.com/products/antazoline-phosphate.html","C17H19N3.H3O4P","Phosphate","N/A","O[P](O)(O)=O.C1CN=C(CN(CC2=CC=CC=C2)C3=CC=CC=C3)N1",2.246,1,1,5]
["E0742","Melengestrol Acetate","c6","L1300-35","in 10mM DMSO",null,"USPNF 2022 Issue 1",null,"Endocrinology","CYP450","Metabolism","Melengestrol Acetate, progestational steroid  suppress the AT3 tumour.",396.52,"2919-66-6",10,25.22,"<1",0,"http://www.selleckchem.com/products/melengestrol-acetate.html","C25H32O4","Acetate",0,"CC(=O)OC1(C(C)=O)C(=C)CC2C3C=C(C)C4=CC(=O)CCC4(C)C3CCC12C",3.696,4,0,3]
["E0818","Quinupristin","d6","L1300-35","in 10mM DMSO","FDA",null,"050748,050747","Infection","Others","Others","Quinupristin, a streptogramin antibiotic, blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits.",1022.22,"120138-50-3",50,48.91,"<1",0,"http://www.selleckchem.com/products/quinupristin.html","C53H67N9O10S","Free base","N/A","CCC1NC(=O)C(NC(=O)C2=C(O)C=CC=N2)C(C)OC(=O)C(NC(=O)C3CC(=O)C(CSC4CN5CCC4CC5)CN3C(=O)C(CC6=CC=C(C=C6)N(C)C)N(C)C(=O)C7CCCN7C1=O)C8=CC=CC=C8",2.515,10,4,10]
["E2438","Ginsenoside Rg3","e6","L1300-35","in 10mM DMSO","CFDA",null,null,"Others","Others","Others","Ginsenoside Rg3 is a ginsenoside found in Panax japonicus var. and Panax ginseng, mainly used for the study of tumor diseases.",785,"11019-45-7",100,127.39,"<1",0,"http://www.selleckchem.com/products/ginsenoside-rg3.html","C42H72O13","Free base","N/A","CC(C)=CCCC(C)(O)C1CCC2(C)C1C(O)CC3C4(C)CCC(OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(C)(C)C4CCC23C",2.295,4,8,10]
["E2665","Tafenoquine","f6","L1300-35","in 10mM DMSO","FDA,DMF",null,"210795,210607","Infection","Anti-infection","Others","Tafenoquine (WR 238605) is an 8-aminoquinoline, used as an anti-malarial prophylactic agent.",463.49,"106635-80-7",93,200.65,"<1",0,"http://www.selleckchem.com/products/tafenoquine.html","C24H28F3N3O3","Free base","WR 238605","COC1=NC2=C(C(=C1)C)C(=C(OC)C=C2NC(C)CCCN)OC3=CC(=CC=C3)C(F)(F)F",5.51,4,2,10]
["E2848","Afoxolaner","g6","L1300-35","in 10mM DMSO","EMA",null,null,"Infection","GABA Receptor","Neuronal Signaling","Afoxolaner (NexGard) is a new insecticide/acaricide molecule from the isoxazoline family that acts on the insect gamma-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod.",625.87,"1093861-60-9",100,159.78,"<1",0,"https://www.selleckchem.com/products/afoxolaner.html","C26H17ClF9N3O3","Free base","NexGard","FC(F)(F)CNC(=O)CNC(=O)C1=CC=C(C2=NOC(C2)(C3=CC(=CC(=C3)Cl)C(F)(F)F)C(F)(F)F)C4=C1C=CC=C4",5.876,4,2,9]
["P1005","Abarelix Acetate","h6","L1300-35","in 10mM DMSO","FDA",null,"021320","Cancer","Others","Endocrinology & Hormones","Abarelix Acetate is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer research.",1476.12,"785804-17-3",100,67.75,100,67.75,"http://www.selleckchem.com/peptide/abarelix-acetate.html","C74H99ClN14O16","Acetate","Ac-D-2-Nal-D-4-Cl-Phe-D-3-Pal-Ser-N-Me-Tyr-D-Asn-Leu-Lys(ipr)-Pro-D-Ala-NH2","CC(C)CC(NC(=O)C(CC(N)=O)NC(=O)C(CC1=CC=C(O)C=C1)N(C)C(=O)C(CO)NC(=O)C(CC2=CN=CC=C2)NC(=O)C(CC3=CC=C(Cl)C=C3)NC(=O)C(CC4=CC5=C(C=CC=C5)C=C4)NC(C)=O)C(=O)NC(CCCCNC(C)C)C(=O)N6CCCC6C(=O)NC(C)C(N)=O.CC(O)=O",-0.464,14,13,38]
["P1032","CCK Octapeptide (Sincalide)","a7","L1300-35","in 10mM DMSO","FDA",null,"017697","Gastroenterology;Inflammation","Others","Others","CCK Octapeptide (Sincalide, Cholecystokinin Octapeptide, CCK-OP, CCK-8, SQ 19,844) is a endogenous peptide hormone found in the intestine and brain that stimulates digestion.",1143.27,"25126-32-3",100,87.47,"<1",0,"http://www.selleckchem.com/products/Sincalide(Kinevac).html","C49H62N10O16S3","Free base","Cholecystokinin Octapeptide, CCK-OP, CCK-8, SQ 19,844","CSCCC(NC(=O)C(CC1=CC=C(O[S](O)(=O)=O)C=C1)NC(=O)C(N)CC(O)=O)C(=O)NCC(=O)NC(CC2=C[NH]C3=CC=CC=C23)C(=O)NC(CCSC)C(=O)NC(CC(O)=O)C(=O)NC(CC4=CC=CC=C4)C(N)=O",-3.722,11,10,33]
["P1069","Ganirelix acetate (Antagon)","b7","L1300-35","in 10mM DMSO","FDA,EMA,CFDA,PMDA,NDC,DMF",null,"214996,212613,204246,021057","Endocrinology","Others","Endocrinology & Hormones","Ganirelix acetate (Antagon,Orgalutran) is a synthetic decapeptide with high antagonistic activity against naturally occurring gonadotropin-releasing hormone (GnRH).",1690.43,"123246-29-7",100,59.16,100,59.16,"http://www.selleckchem.com/peptide/ganirelix-acetate-antagon.html","C80H113ClN18O13.2C2H4O2","Diacetate","Orgalutran","CCNC(NCC)=NCCCCC(NC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C(CO)NC(=O)C(CC2=CN=CC=C2)NC(=O)C(CC3=CC=C(Cl)C=C3)NC(=O)C(CC4=CC5=C(C=CC=C5)C=C4)NC(C)=O)C(=O)NC(CC(C)C)C(=O)NC(CCCCN=C(NCC)NCC)C(=O)N6CCCC6C(=O)NC(C)C(N)=O.CC(O)=O.CC(O)=O",3.056,16,16,48]
["P1109","Linaclotide","c7","L1300-35","in 10mM DMSO","FDA,EMA,CFDA,PMDA,DMF",null,"211255,209564,202811","Gastroenterology","Others","Others","Linaclotide is a potent and selective guanylate cyclase C (GC-C) agonist that elicits pharmacological effects locally in the gastrointestinal tract.",1526.75,"851199-59-2",100,65.5,"<1",0,"http://www.selleckchem.com/products/linaclotide.html","C59H79N15O21S6","Free base",0,"CC(O)C1NC(=O)C2CSSCC3NC(=O)C(N)CSSCC(NC(=O)C(CSSCC(NC(=O)CNC1=O)C(=O)NC(CC4=CC=C(O)C=C4)C(O)=O)NC(=O)C(CC5=CC=C(O)C=C5)NC(=O)C(CCC(O)=O)NC3=O)C(=O)NC(CC(N)=O)C(=O)N6CCCC6C(=O)NC(C)C(=O)N2",-7.707,16,17,13]
["P1151","Difelikefalin","d7","L1300-35","in 10mM DMSO","FDA,EMA,NDC",null,"214916","Inflammation","Opioid Receptor","GPCR & G Protein","Difelikefalin (CR-845, FE-202845), a peripherally restricted and selective agonist of kappa opioid receptor (KOR), produces anti-inflammatory effects and has the potential in modulating pruritus in conditions such as chronic kidney disease.",679.85,"1024828-77-0",100,147.09,100,147.09,"http://www.selleckchem.com/products/difelikefalin.html","C36H53N7O6","Free base",0,"CC(C)CC(NC(=O)C(CC1=CC=CC=C1)NC(=O)C(N)CC2=CC=CC=C2)C(=O)NC(CCCCN)C(=O)N3CCC(N)(CC3)C(O)=O",-1.787,5,6,18]
["E4074","p-Toluic acid","e7","L1300-35","in 10mM DMSO",null,"USP42-NF37",null,"Metabolic Disease","Endogenous Metabolite","Metabolism","p-Toluic Acid belongs to the class of organic compounds known as benzoic acids. 4-Methylbenzoic acid has been primarily detected in saliva. Within the cell, 4-methylbenzoic acid is primarily located in the cytoplasm.",136.15,"99-94-5",0,">10",0,0,"https://www.selleckchem.com/products/p-toluic-acid.html","C8H8O2","free base","p-Toluic Acid","CC1=CC=C(C=C1)C(O)=O",1.946,1,0,1]
["E4112","Menthol","f7","L1300-35","in 10mM DMSO","PMDA;FDA; NDC","USP42-NF37",null,"Pain","Others","Others","Menthyl alcohol is an organic compound made synthetically or obtained from peppermint or mint oils with flavoring and local anesthetic properties.",156.26,"1490-04-6",0,">10",0,0,"https://www.selleckchem.com/products/menthol.html","C10H20O","free base","Menthyl alcohol","CC(C)C1CCC(C)CC1O",2.779,0,1,1]
["E4421","Testosterone acetate","h7","L1300-35","in 10mM DMSO","FDA",null,null,"Reproductive system","Others","Others","Testosterone acetate is a hormone with in vitro antitumor activity.",330.47,"1045-69-8",0,">10",0,0,"https://www.selleckchem.com/products/testosterone-acetate.html","C21H30O3","Ester","Testosterone acetate","CC(=O)OC1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C",3.852,3,0,2]
["E4422","DL-Adrenaline Hydrochloride","a8","L1300-35","in 10mM DMSO","FDA",null,null,"Endocrine system","Adrenergic Receptor","Neuroscience; GPCR/G Protein","DL-Adrenaline Hydrochloride is the hydrochloride salt of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing activities.",219.67,"329-63-5",0,">10",0,0,"https://www.selleckchem.com/products/dl-adrenaline-hydrochloride.html","C9H13NO3·HCl","hydrochloride","DL-Adrenaline Hydrochloride","Cl.CNCC(O)C1=CC(=C(O)C=C1)O",0.754,0,4,3]
["E4434","Phenylephrine","b8","L1300-35","in 10mM DMSO","FDA,EMA,HMA,NDC,DMF,PMDA","JP18;BP2024;USP-NF2024;EP11.0;IP2010","003702,040902,216859,213318,040674,040654,088870,211081,088815,203200,210665,208905,007953,212909,211920,200963,210183,217069,210333,088868,211078,040675,210666,088816,088896,022113,210025,203510,022565,040660,013296,008306,088761,088764,088897,084300,210697","Cardiovascular Disease/Endocrinology/Cancer","Adrenergic Receptor","GPCR/G Protein;Neuroscience","Phenylephrine is a selective α1-adrenoceptor agonist ( pKi: 5.86, 4.87 and 4.70 for α1D, α1B, and α1A receptors respectively).",167.21,"59-42-7",0,">10",0,0,"https://www.selleckchem.com/products/phenylephrine.html","C9H13NO2","free base","Phenylephrine","CNCC(O)C1=CC(=CC=C1)O",0.615,0,3,3]
["E4029","Tyramine hydrochloride","c8","L1300-35","in 10mM DMSO","DMF",null,null,"Catecholamine releasing agents","Others","Others","Tyramine hydrochloride is a biogenic trace amine that is generated via the decarboxylation of the amino acid tyrosine, exhibiting neuromodulatory properties as well as cardiovascular and immunological effects.",173.64,"60-19-5",0,">10",0,0,"https://www.selleckchem.com/products/tyramine-hydrochloride.html","C8H12ClNO","hydrochloride","Tyramine hydrochloride","Cl.NCCC1=CC=C(O)C=C1",1.397,0,2,2]
["E2164","Citric acid hydrate","d8","L1300-35","in 10mM DMSO","FDA,PMDA,HMA,NDC,DMF","JP18;BP2024;USP-NF2024;EP11.0;IP2010","205743,018904,209589,021314,202535,208352,019481,212789,018519","Metabolic Disease/Inflammation/Immunology","Others","Others","Citric Acid Monohydrate is a tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It maintains stability of active ingredients and is used as a preservative.",210.14,"5949-29-1",0,">10",0,0,"https://www.selleckchem.com/products/citric-acid-monohydrate.html","C6H10O8","monohydrate","Citric acid monohydrate","O.OC(=O)CC(O)(CC(O)=O)C(O)=O",-1.526,3,0,5]
["E4499","Levomenol","e8","L1300-35","in 10mM DMSO",null,"BP2017, BP2013, BP2010",null,"Inflammation/Immunology; Neurological Disease","Others","Others","Levomenol is a sesquiterpene alcohol that has been found in the essential oils of several aromatic plants, with exerts antioxidant, anti-inflammatory, and anti-apoptotic activities.",222.37,"23089-26-1",0,">10",0,0,"https://www.selleckchem.com/products/levomenol.html","C15H26O","Alcohol","Levomenol","CC(C)=CCCC(C)(O)C1CCC(=CC1)C",4.309,0,0,4]
["E4084","Gallic acid (hydrate)","f8","L1300-35","in 10mM DMSO","NDC","BP2023;EP8.7",null,"Cancer/Inflammation/Immunology","COX","Immunology & Inflammation","Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2). It has antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities.",188.13,"5995-86-8",0,">10",0,0,"https://www.selleckchem.com/products/gallic-acid-hydrate.html","C7H8O6","hydrate","3,4,5-Trihydroxybenzoic acid","O.OC(=O)C1=CC(=C(O)C(=C1)O)O",0.526,1,3,1]
["E4226","7-Ketolithocholic acid","g8","L1300-35","in 10mM DMSO","DMF",null,null,"Metabolic Disease","Others","Metabolism","7-Ketolithocholic acid is a secondary bile acid that is absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion.",390.56,"4651-67-6",0,">10",0,0,"https://www.selleckchem.com/products/7-ketolithocholic-acid.html","C24H38O4","acid","3α-Hydroxy-7-oxo-5β-cholanic acid","CC(CCC(O)=O)C1CCC2C3C(CCC12C)C4(C)CCC(O)CC4CC3=O",3.971,2,1,4]
["E4271","1-Naphthol","h8","L1300-35","in 10mM DMSO",null,"USP42-NF37",null,"Others","Others","Others","1-Naphthol is an organic compound obtained from the aromatic hydrocarbon naphthalene. It acts as a catalyst in the polymerization process of vinyl monomers and plays a vital role in the synthesis of 1-naphthylacetic acid and its derivatives as a reactant.",144.17,"90-15-3",0,">10",0,0,"https://www.selleckchem.com/products/1-naphthol.html","C10H8O","free base","Furro ER, NSC 9586, Nako TRB, 1-hydroxy-naphthalene","OC1=CC=CC2=C1C=CC=C2",2.496,0,1,0]
["E4419","Ethyl linoleate","a9","L1300-35","in 10mM DMSO","CFDA","BP2023;EP8.7",null,"Cardiovascular Disease","Others","Natural Products","Ethyl linoleate (Linoleic Acid ethyl ester) can be extracted as a bioactive component from the hexane extract of Dioscorea. batatas Decne. Ethyl linoleate inhibits the development of atherosclerotic lesions and the expression of inflammatory mediators.",308.5,"544-35-4",0,">10",0,0,"https://www.selleckchem.com/products/ethyl-linoleate.html","C20H36O2","ester","Linoleic Acid ethyl ester; Mandenol","CCCCC/C=C\\C\\C=C/CCCCCCCC(=O)OCC",6.99,2,0,16]
["E0359","Evocalcet","b9","L1300-35","in 10mM DMSO","PMDA",null,null,"Hyperparathyroidism and Secondary Hyperparathyroidism.","CaSR","GPCR & G Protein","Evocalcet (KHK7580) is an novel oral calcimimetic agent which acts via allosteric activation of the calcium sensing receptor (CaSR). Evocalcet (0, 20 and 60 nM) dose-dependently increases cytoplasmic  [Ca2+] concentrations  with an EC50 value of 92.7 nM in hCaR-HEK293 cells.",374.48,"870964-67-3",75,200.28,"<1",0,"https://www.selleckchem.com/products/evocalcet.html","C24H26N2O2","free base","KHK7580","CC(NC1CCN(C1)C2=CC=C(CC(O)=O)C=C2)C3=CC=CC4=C3C=CC=C4",1.334,1,1,6]
["E1310","DPCPX","c9","L1300-35","in 10mM DMSO","DMF",null,null,"Cystic Fibrosis.","Others","Others","DPCPX (PD 116948), a xanthine derivative, is a highly potent and selective adenosine A1 receptor (ADORA1) antagonist, with a Ki of 0.46 nM.",304.39,"102146-07-6",61,200.4,"<1",0,"https://www.selleckchem.com/products/dpcpx.html","C16H24N4O2","free base","PD 116948","CCCN1C(=O)N(CCC)C2=C([NH]C(=N2)C3CCCC3)C1=O",3.37,3,1,5]
["E1321","Digitonin","d9","L1300-35","in 10mM DMSO",null,"BP2023;EP8.7",null,null,"Others","Others","Digitonin, a steroidal saponin and glycoside obtained from <i>Digitalis purpurea</i>, has strong lytic activity on various cell membranes with an IC50 of 15.1 µM on sheep RBC membranes.",1229.31,"11024-24-1",100,81.35,"<1",0,"https://www.selleckchem.com/products/digitonin.html","C56H92O29","free base",0,"CC1CCC2(OC1)OC3C(O)C4C5CCC6CC(OC7OC(CO)C(OC8OC(CO)C(O)C(OC9OCC(O)C(O)C9O)C8OC%10OC(CO)C(O)C(OC%11OC(CO)C(O)C(O)C%11O)C%10O)C(O)C7O)C(O)CC6(C)C5CCC4(C)C3C2C",-5.207,12,17,14]
["E1410","Fluspirilene","e9","L1300-35","in 10mM DMSO","Other Countries",null,null,"schizophrenia.","Calcium Channel","Transmembrane Transporters","Fluspirilene(R 6218; Redeptin) is a non-competitive antagonist of L-type calcium channels with an IC50 of 0.03 μM in cell-free assays. Fluspirileneis a long-acting injectable depot antipsychotic agent used for schizophrenia.",475.57,"1841-19-6",95,199.76,"<1",0,"https://www.selleckchem.com/products/fluspirilene.html","C29H31F2N3O","free base","R 6218, Redeptin","FC1=CC=C(C=C1)C(CCCN2CCC3(CC2)N(CNC3=O)C4=CC=CC=C4)C5=CC=C(F)C=C5",5.545,1,1,7]
["E2411","Taurodeoxycholic acid sodium hydrate","f9","L1300-35","in 10mM DMSO",null,"BP2023",null,"Metabolic Disease","S1PR Agonist","GPCR & G Protein","Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a bile acid, is an amphiphilic surfactant molecule synthesized from cholesterol in the liver. It activates S1PR2 pathway in addition to the TGR5 pathway.",540.71,"110026-03-4",100,184.94,100,184.94,"https://www.selleckchem.com/products/taurohyodeoxycholic-acid-sodium-salt-hydrate.html","C26H45NO6S.H2O.Na","Sodium hydrate",0,"O.[Na;v0].CC(CCC(=O)NCC[S](O)(=O)=O)C1CCC2C3CCC4CC(O)CCC4(C)C3CC(O)C12C",2.858,1,3,7]
["E2866","Sodium tetradecyl sulfate","g9","L1300-35","in 10mM DMSO","FDA;HMA;NDC;DMF","BP2023","ANDA(040541;209937)","Uncomplicated competent valves, simple dilation varicose veins of legs","Others","Others","Sodium tetradecyl sulfate, a detergent sclerosant, is widely used agent for esophageal varices and varicose veins.",317.44,"1191-50-0 ",63,198.46,63,198.46,"https://www.selleckchem.com/products/sodium-tetradecyl-sulfate.html","C14H30O4S.Na","sulfate",0,"[Na;v0].CCCCCCCCCCCCCCO[S](O)(=O)=O",5.322,1,0,14]
["E2868","Naloxegol Oxalate","h9","L1300-35","in 10mM DMSO","FDA",null,null,"opioid-induced constipation (OIC)","Opioid Receptor","Neuronal Signaling","Naloxegol oxalate (NKTR-118 oxalate) is a μ-opioid-receptor antagonist with a Ki of 33.8 nM. Naloxegol oxalate inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation.",741.82,"1354744-91-4",100,134.8,100,134.8,"https://www.selleckchem.com/products/naloxegol-oxalate.html","C34H53NO11.C2H2O4","Oxalate",0,"COCCOCCOCCOCCOCCOCCOCCOC1CCC2(O)C3CC4=C5C(=C(O)C=C4)OC1C25CCN3CC=C.OC(=O)C(O)=O",-2.512,11,1,25]
["E2871","Trovafloxacin Mesylate","a10","L1300-35","in 10mM DMSO","FDA; EMA","Pharmacopoeia",null,"antibiotic","TRP Channel","Transmembrane Transporters, Microbiology  & Antibiotic","Trovafloxacin mesylate, a broad-spectrum quinolone antibiotic, is a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current.",512.46,"147059-75-4",100,195.14,"<1",0,"https://www.selleckchem.com/products/trovafloxacin-mesylate.html","C20H15F3N4O3.CH4O3S","Mesylate",0,"C[S](O)(=O)=O.NC1C2CN(CC12)C3=C(F)C=C4C(=O)C(=CN(C5=C(F)C=C(F)C=C5)C4=N3)C(O)=O",-0.68,3,1,3]
["E2872","Clocortolone Pivalate","b10","L1300-35","in 10mM DMSO","FDA;NDC;DMF","USP-NF2023","NDA (017765);ANDA (206370)","Dermatoses","Others","Others","Clocortolone pivalate is a mid-potent topical corticosteroid available as a 0.1% emollient cream used in the treatment of corticosteroid-responsive dermatoses.",495.02,"34097-16-0",33,66.66,"<1",0,"https://www.selleckchem.com/products/clocortolone-pivalate.html","C27H36CIFO5","free base",0,"CC1CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(Cl)C(O)CC2(C)C1C(=O)COC(=O)C(C)(C)C",4.404,4,1,5]
["E2873","Laropiprant","c10","L1300-35","in 10mM DMSO","DMF; EMA",null,null,"Hyperlipidaemia(PHASE 3)","Prostaglandin Receptor","GPCR & G Protein","Laropiprant is a potent and selective prostaglandin D2 (DP) receptor antagonist with a Ki value of 0.57 nM.",435.9,"571170-77-9",87,199.59,"<1",0,"https://www.selleckchem.com/products/laropiprant.html","C21H19CIFNO4S","free base",0,"C[S](=O)(=O)C1=C2[N](CC3=CC=C(Cl)C=C3)C4=C(CCC4CC(O)=O)C2=CC(=C1)F",4.876,3,0,5]
["E2874","Sofpironium bromide","d10","L1300-35","in 10mM DMSO","PMDA;DMF",null,null,"PAH primary axillary hyperhidrosis","AChR","Neuronal Signaling","Sofpironium bromide (BBI 4000) is an anticholinergic agent that reduces sweat by inhibiting  M3 muscarinic receptors  in eccrine glands.",470.4,"1628106-94-4",94,199.83,94,199.83,"https://www.selleckchem.com/products/sofpironium-bromide.html","C22H32NO5.Br","bromide","BBI 4000","[Br-].CCOC(=O)C[N+]1(C)CCC(C1)OC(=O)C(O)(C2CCCC2)C3=CC=CC=C3",-0.905,4,0,9]
["E2875","Levobunolol(l-Bunolol) hydrochloride","e10","L1300-35","in 10mM DMSO","FDA",null,null,"ocular hypertension or open-angle glaucoma.","Adrenergic Receptor","Neuronal Signaling","Levobunolol (l-Bunolol) hydrochloride is a potent and nonselective β-adrenergic receptor antagonist with an IC50 of 48 μM.",327.85,"27912-14-7 ",66,201.31,66,201.31,"https://www.selleckchem.com/products/levobunolol-l-bunolol-hydrochloride.html","C17H25NO3.ClH","hydrochloride",0,"Cl.CC(C)(C)NCC(O)COC1=C2CCCC(=O)C2=CC=C1",2.74,2,2,6]
["E2876","pemafibrate","f10","L1300-35","in 10mM DMSO","PMDA",null,null,"Nonalcoholic fatty liver disease (NAFLD)","PPAR","Metabolism","Pemafibrate(K-877) is a selective agonist of peroxisome proliferator-activated receptor (PPAR) α with an IC50  of 10 µM.",490.55,"848259-27-8",98,199.78,"<1",0,"https://www.selleckchem.com/products/pemafibrate.html","C28H30N2O6","free base","K-877","CCC(OC1=CC=CC(=C1)CN(CCCOC2=CC=C(OC)C=C2)C3=NC4=CC=CC=C4O3)C(O)=O",5.794,6,0,13]
["E2878","iothalamate sodium","g10","L1300-35","in 10mM DMSO","FDA;NDC;DMF",null,"NDA (017279)","Renal disease","Others","Others","Iothalamate sodium is the sodium salt form of iothalamate, an organic iodine compound and a radiographic contrast medium.",636.9,"1225-20-3",100,157.01,"<1",0,"https://www.selleckchem.com/products/iothalamate-sodium.html","C11H9I3N2O4.Na","Sodium",0,"[Na;v0].CNC(=O)C1=C(I)C(=C(I)C(=C1I)NC(C)=O)C(O)=O",1.522,3,2,3]
["E2880","methylnaltrexone bromide","h10","L1300-35","in 10mM DMSO","FDA",null,null,"opioid-induced constipation","Opioid Receptor","Neuronal Signaling","Methylnaltrexone bromide is an antagonist of µ-opioid receptor that reduces the viability of lung cancer cells by inhibiting Src activation.",436.34,"73232-52-7",100,229.18,100,229.18,"https://www.selleckchem.com/products/methylnaltrexone-bromide.html","C21H26NO4.Br","Bromide",0,"[Br-].C[N+]1(CCC23C4OC5=C(O)C=CC(=C25)CC1C3(O)CCC4=O)CC6CC6",-2.116,2,1,2]
["E2901","(-)-Isoproterenol hydrochloride","a11","L1300-35","in 10mM DMSO","NDC;DMF","USP-NF2023",null,"Treatment of bradycardia; Bronchodilators","Adrenergic Receptor","Neuronal Signaling","(-)-Isoproterenol hydrochloride is an agonist of  beta-adrenergic receptor. (-)-Isoproterenol hydrochloride is also used in the treatment of bradycardia; bronchodilator.",247.72,"5984-95-2",50,201.84,50,201.84,"https://www.selleckchem.com/products/---isoproterenol-hydrochloride.html","C11H17NO3.CIH","Hydrochloride",0,"Cl.CC(C)NCC(O)C1=CC(=C(O)C=C1)O",1.481,0,4,4]
["E2902","Sodium Pyruvate","b11","L1300-35","in 10mM DMSO","DMF","BP2023",null,"Metabolic Disease","Others","Others","Sodium Pyruvate(Sodium 2-oxopropanoate) is a compound produced in the glycolytic pathway. Sodium Pyruvate is a free radical scavenger that can scavenge ROS.",111.05,"113-24-6",4,36.02,22,198.11,"https://www.selleckchem.com/products/sodium-pyruvate.html","C3H4O3.Na","Sodium","Sodium 2-oxopropanoate","[Na;v0].CC(=O)C(O)=O",-0.329,2,0,1]
["E2944","Norepinephrine hydrochloride","c11","L1300-35","in 10mM DMSO","FDA",null,null,"blood pressure","Adrenergic Receptor","GPCR & G Protein","Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent agonist of adrenergic receptor (AR). Norepinephrine activates α1, α2, β1 receptors.",205.64,"329-56-6",41,199.38,41,199.38,"https://www.selleckchem.com/products/norepinephrine-hydrochloride.html","C8H11NO3.ClH","Hydrochloride","Levarterenol; L-Noradrenaline","Cl.NCC(O)C1=CC(=C(O)C=C1)O",0.323,0,4,2]
["E2964","Norepinephrine tartrate","e11","L1300-35","in 10mM DMSO","PMDA;NMPA",null,null,"hypotensive states and as an adjunct treatment during cardiac arrest","Adrenergic Receptor","GPCR & G Protein","Norepinephrine tartrate is a potent agonist of adrenergic receptor (AR). Norepinephrine activates α1, α2, β1 receptors.",319.27,"3414-63-9",64,200.46,64,200.46,"https://www.selleckchem.com/products/norepinephrine-tartrate.html","C8H11NO3.C4H6O6","potassium",0,"NCC(O)C1=CC(=C(O)C=C1)O.OC(C(O)C(O)=O)C(O)=O",-4.202,2,6,5]
["E2968","Zinc sulfate heptahydrate","f11","L1300-35","in 10mM DMSO","FDA; NMPA; PMDA",null,null,"zinc deficiency","Others","Others","Zinc sulfate heptahydrate is a hydrate that is the heptahydrate form of zinc sulfate. Zinc sulfate heptahydrate is a dietary supplement used for zinc deficiency and can also accelerate the rate of healing. It is also used in prepration of zinc tris(thiourea) sulphate (ZTS), a semiorganic nonlinear optic (NLO) material that may be useful in laser fusion experiments and in second-harmonic-generation (SHG) devices.",289.58,"7446-20-0",36,124.32,36,124.32,"https://www.selleckchem.com/products/zinc-sulfate-heptahydrate.html","H2O4S.7H2O.Zn","Salt",0,"O.[Zn].O[S](O)(=O)=O",-0.815,0,0,0]
["E2970","Gramicidin","g11","L1300-35","in 10mM DMSO","FDA",null,null,"antibiotic","Bacterial","Microbiology","Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) is an antimicrobial peptide that destroys gram-positive bacteria. It inhibits the growth of bacteria by forming pores and channels in the cell wall, which increase its permeability to monovalent cations.",1882.29,"1405-97-6",100,53.13,"<1",0,"https://www.selleckchem.com/products/gramicidin.html",0,"Free base",0,0,0,0,0,0]
["E4010","L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride","h11","L1300-35","in 10mM DMSO","Other countries","JP17,USP42-NF37",null,"Cancer;Parkinson's disease.","Others","Others","L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride(Melevodopa hydrochloride) is a precursor to L-DOPA. It is an antiparkinsonian agent L-DOPA methyl ester that  elicits antitumor functionality in leukemia and melanoma.",247.68,"1421-65-4",50,201.87,50,201.87,"https://www.selleckchem.com/products/l-3,4-dihydroxyphenylalanine-methyl-ester-hydrochloride.html","C10H13NO4.ClH","Ester","Melevodopa hydrochloride","Cl.COC(=O)C(N)CC1=CC(=C(O)C=C1)O",0.997,2,3,4]
["E4013","Melanin","a2","L1300-36","in 10mM DMSO","NDC; DMF",null,null,"Anti-inflammatories","Others","Others","Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation.",318.28,"8049-97-6",64,201.08,"<1",0,"https://www.selleckchem.com/products/melanin.html",0,"Polymer",0,0,0,0,0,0]
["E4017","Calcium chloride dihydrate","b2","L1300-36","in 10mM DMSO","HMA; DMF","BP2023; EP11.0",null,"calcium supplements","Other","Other","Calcium chloride dihydrate is a moisture-resistant, cheap, and commonly available calcium salt. It is used as a calcium supplement in the DMEM (Dulbecco's modified Eagle's medium) for use in cell culture studies and to prepare the synthetic brine solution.",147.01,"10035-04-8",29,197.27,29,197.27,"https://www.selleckchem.com/products/calcium-chloride-dihydrate.html","CaCl2.2H2O","Salt",0,"O.Cl[Ca]Cl",0.764,0,0,0]
["S1423","Dobutamine HCl","c2","L1300-36","in 10mM DMSO","FDA;NDC;PMDA;DMF","JP18;BP2023;USP-NF2023","020201;020255;074086;074277","Cardiac decompensation \nDiagnostic agent Coronary artery disease","Adrenergic Receptor","Neuronal Signaling","Dobutamine(Dobutrex) hydrochloride is a selective potent agonist of β1-AR (β-1 adrenergic receptor) and exhibits weak activity at α1-AR and β2-AR. Dobutamine is a sympathomimetic compound that effectively restores blood pressure in hypotensive dogs and human patients by improving myocardial contractility and increasing cardiac output (CO).",337.84,"49745-95-1",68,201.28,"<1",0,"https://www.selleckchem.com/products/Dobutamine-hydrochloride.html","C18H23NO3&middot;HCl","Hydrochloride","Dobutrex","Cl.CC(CCC1=CC=C(O)C=C1)NCCC2=CC(=C(O)C=C2)O",4.083,0,4,7]
["S9865","CB-5339","d2","L1300-36","in 10mM DMSO","DMF",null,null,"Cancer(PHASE1);Acute myeloid leukaemia; Myelodysplastic syndromes","p97","Ubiquitin","CB-5339 is a potent p97/Valosin Containing Protein (VCP) inhibitor with an IC50 of 9 nM.",412.49,"1863952-15-1",100,242.43,"<1",0,"https://www.selleckchem.com/products/cb-5339.html","C24H24N6O","Free base",0,"CC1=CC2=C(C=CC=C2[N]1C3=NC(=C4CCCN=C4N3)NCC5=CC=CC=C5)C(N)=O",3.683,3,3,5]
["E0109","Fezolinetant","e2","L1300-36","in 10mM DMSO","FDA",null,"NDA (216578)","Moderate to severe vasomotor symptoms","Neurokinin Receptor","GPCR & G Protein","Fezolinetant (ESN-364) is a potential antagonist of the neurokinin 3 receptor (NK3R). It interrupts pulsatile lh secretion and moderates levels of ovarian hormones throughout the menstrual cycle.",358.39,"1629229-37-3",72,200.9,"<1",0,"https://www.selleckchem.com/products/fezolinetant.html","C₁₆H₁₅FN₆OS","peptide","ESN-364","CC1N(CC[N]2C1=NN=C2C3=NC(=NS3)C)C(=O)C4=CC=C(F)C=C4",1.714,5,0,2]
["E2363","Etrasimod(APD334)","f2","L1300-36","in 10mM DMSO","FDA, NDC",null,216956,"Inflammation/Immunology","S1P Receptor","GPCR & G Protein","Etrasimod(APD334) is a potent, selective and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor with an EC50 value of 1.88 nM in CHO cells.",457.49,"1206123-37-6",92,201.1,"<1",0,"https://www.selleckchem.com/products/apd334.html","C26H26F3NO3","Free base","APD334","OC(=O)CC1CCC2=C1[NH]C3=CC=C(OCC4=CC(=C(C=C4)C5CCCC5)C(F)(F)F)C=C23",6.935,2,1,7]
["E2869","Propiolactone","g2","L1300-36","in 10mM DMSO","FDA;NDC;DMF",null,null,"Anti-Infective Agents","Others","Others","Propiolactone(β-Propiolactone), a sterilizing and sporicidal agent, is used to sterilize blood plasma, vaccines, tissue grafts, surgical instruments and enzymes.",72.06,"57-57-8",100,1387.73,"<1",0,"https://www.selleckchem.com/products/propiolactone.html","C3H4O2","lactone",0,"O=C1CCO1",-0.045,2,0,0]
["E4446","S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt","h2","L1300-36","in 10mM DMSO","NMPA",null,null,"Cancer; Inflammation/Immunology; Neurological Disease","Others","Others","S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt (AdoMet) is a methyl donor and cofactor for enzyme-catalyzed methylations including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). It has an anti-apoptotic activity and can be used for the treatment of depression, liver cirrhosis, cholestasis and degenerative joint disease.",570.64,"52248-03-0",100,175.24,100,175.24,"https://www.selleckchem.com/products/s-(5-adenosyl)-l-methionine-p-toluenesulfonate-salt.html","C15H23N6O5S.C7H7O3S","Salt","AdoMet","C[S+](CCC(N)C(O)=O)CC1OC(C(O)C1O)[N]2C=NC3=C(N)N=CN=C23.CC4=CC=C(C=C4)[S]([O-])(=O)=O",-4.85,5,4,8]
["E4464","Hexythiazox","a3","L1300-36","in 10mM DMSO","NMPA",null,null,"Infection","Others","Others","Hexythiazox is a selective acaricide with ovicidal, larvicidal and nymphicidal activities. It is widely used for chemical control of mites on cotton, fruits and vegetables.",352.88,"78587-05-0",71,201.2,"<1",0,"https://www.selleckchem.com/products/hexythiazox.html","C17H21ClN2O2S","Free base",0,"CC1C(SC(=O)N1C(=O)NC2CCCCC2)C3=CC=C(Cl)C=C3",4.892,2,1,2]
["E4466","Saquinavir Mesylate","b3","L1300-36","in 10mM DMSO","EMA; FDA","JP17",null,"treatment of HIV-1 with advanced immunodeficiency.","HIV Protease","Proteases","Saquinavir mesylate (Ro 31-8959/003) is a potent inhibitor of HIV Protease used in antiretroviral therapy. It blocks proteolysis of polyproteins containing either wild-type or single-chain dimer retroviral proteinase (PR).",766.95,"149845-06-7",50,65.19,"<1",0,"https://www.selleckchem.com/products/saquinavir-mesylate.html","C38H50N6O5.CH4O3S","Mesylate","Ro 31-8959/003","CC(C)(C)NC(=O)C1CC2CCCCC2CN1CC(O)C(CC3=CC=CC=C3)NC(=O)C(CC(N)=O)NC(=O)C4=NC5=C(C=CC=C5)C=C4.C[S](O)(=O)=O",3.253,5,5,13]
["E4467","Temozolomide Acid","c3","L1300-36","in 10mM DMSO","FDA",null,null,"Cancer(glioblastoma multiforme and refractory anaplastic astrocytoma.)","Others","Others","Temozolomide acid is a carboxylic acid derivative of Temozolomide. It has an anticancer activity by causing breaks in DNA double strand, cell cycle arrest, and eventually cell death.",195.14,"113942-30-6",39,199.86,"<1",0,"https://www.selleckchem.com/products/temozolomide-acid.html","C6H5N5O3","Acid",0,"CN1N=NC2=C(N=C[N]2C1=O)C(O)=O",0.679,5,0,1]
["E4472","Clavulanic acid","d3","L1300-36","in 10mM DMSO","NDC;HMA","BP2023;NF2023;IP2010",null,"antibacterial effects(PHASE 2)","β-lactamase","Microbiology","Clavulanic acid is a naturally occurring, powerful bacterial β-lactamase inhibitor. The beta-lactam ring found in clavulanic acid binds to the active site of beta-lactamase, resulting in enzyme inactivation and enhancing the antibacterial activity of beta-lactam antibiotics like amoxicillin.",199.16,"58001-44-8",40,200.84,40,200.84,"https://www.selleckchem.com/products/clavulanic-acid.html","C8H9NO5","Acid",0,"OC\\C=C\\1OC2CC(=O)N2C1C(O)=O",-1.235,3,1,2]
["E4474","Infigratinib Phosphate","e3","L1300-36","in 10mM DMSO","FDA",null,null,"Cancer","FGFR","Angiogenesis","Infigratinib Phosphate (NVP-BGJ398 phosphate) is the phosphate salt form of infigratinib, an orally bioavailable pan-inhibitor of human  fibroblast growth factor receptors (FGFRs)  with IC50 of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for  FGFR1, FGFR2, FGFR3, and FGFR4 respectively. It also has potential antiangiogenic, antineoplastic and antitumor activities.",658.47,"1310746-10-1",100,151.87,"<1",0,"https://www.selleckchem.com/products/infigratinib-phosphate.html","C26H31Cl2N7O3.H3O4P","Phosphate","NVP-BGJ398 phosphate","CCN1CCN(CC1)C2=CC=C(NC3=CC(=NC=N3)N(C)C(=O)NC4=C(Cl)C(=CC(=C4Cl)OC)OC)C=C2.O[P](O)(O)=O",4.874,5,2,8]
["E4477","Lumateperone","f3","L1300-36","in 10mM DMSO","FDA",null,null,"schizophrenia.","5-HT Receptor","Neuronal Signaling","Lumateperone (ITI-007) is an antagonist of 5-HT2A receptor with Ki of 0.54 nM. It has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia.",393.5,"313368-91-1",79,200.76,"<1",0,"https://www.selleckchem.com/products/lumateperone.html","C24H28FN3O","Free base","ITI-007","CN1CCN2C3CCN(CCCC(=O)C4=CC=C(F)C=C4)CC3C5=CC=CC1=C25",3.765,1,0,5]
["E4478","Acetrizoic acid","g3","L1300-36","in 10mM DMSO","DMF",null,null,"an X-ray contrast agent.","Others","Others","Acetrizoic acid is a first monomeric, water-soluble, iodinated ionic compound used as an X-ray contrast agent having nephrotropic property that can be intravenously administered for clinical applications.",556.86,"85-36-9",100,179.58,"<1",0,"https://www.selleckchem.com/products/acetrizoic-acid.html","C9H6I3NO3","Acid",0,"CC(=O)NC1=C(I)C(=C(I)C=C1I)C(O)=O",2.314,2,1,2]
["S7236","Cariprazine hydrochloride","h3","L1300-36","in 10mM DMSO","EMA; FDA",null,null,"schizophrenia and acute manic or mixed episodes due to bipolar I disorder.","Dopamine Receptor","Neuronal Signaling","Cariprazine hydrochloride(RGH188 hydrochloride) is a novel antipsychotic agent and is a highly selective partial agonist of dopamineD2 and D3 and 5HT1A receptors, with preferential binding to the D3 receptor. It exhibits high selectivity and affinity to dopamine D3 (Ki = 0.085 nM) and D2 (Ki = 0.49 nM) receptors and has moderate affinity for the 5-HT1A receptor (Ki = 2.6 nM).",463.87,"1083076-69-0",12,25.87,"<1",0,"https://www.selleckchem.com/products/cariprazine-rgh-188.html","C21H32Cl2N4O.HCl","Hydrochloride","RGH188 hydrochloride","Cl.CN(C)C(=O)NC1CCC(CC1)CCN2CCN(CC2)C3=C(Cl)C(=CC=C3)Cl",4.934,1,1,5]
["E1280","Ubrogepant","a4","L1300-36","in 10mM DMSO","FDA",null,null,"migraine","CGRP Receptor","GPCR & G Protein","Ubrogepant (MK-1602) is an antagonist of human calcitonin gene-related peptide receptor (CGRP). It potently blocks human α–CGRP–stimulated cAMP responses with an IC50 of 0.081 nM in human CGRP receptor-expressing HEK293 cells.",549.54,"1374248-77-7",100,181.97,"<1",0,"https://www.selleckchem.com/products/ubrogepant.html","C29H26F3N5O3","Free base","MK-1602","CC1C(CC(NC(=O)C2=CN=C3CC4(CC3=C2)C(=O)NC5=NC=CC=C45)C(=O)N1CC(F)(F)F)C6=CC=CC=C6",2.897,5,2,5]
["E1445","Palovarotene","b4","L1300-36","in 10mM DMSO","EMA","JP17",null,"heterotopic ossification in patients with Fibrodysplasia Ossificans Progressiva (FOP)","Retinoid Receptor","Metabolism","Palovarotene (R 667; Ro 3300074) is a nuclear retinoic acid receptor γ (RAR-γ) agonist. It reduces heterotopic ossification (HO) in cultures and in murine and rat fibrodysplasia ossificans progressiva (FOP) models.",414.54,"410528-02-8",83,200.22,"<1",0,"https://www.selleckchem.com/products/palovarotene.html","C27H30N2O2","Free base","R 667, Ro 3300074","CC1(C)CCC(C)(C)C2=CC(=C(C[N]3C=CC=N3)C=C12)\\C=C\\C4=CC=C(C=C4)C(O)=O",6.108,2,0,5]
["P1127","Pasireotide","c4","L1300-36","in 10mM DMSO","FDA;NDC",null,"200677;203255","Cushing’s disease","SSTR","Endocrinology & Hormones","Pasireotide (SOM230) is a multi-receptor ligand somatostatin analogue with high binding affinity for somatostatin receptor (SSTR) subtypes sst1,2,3 and sst5. It potently suppresses GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing’s disease.",1047.21,"396091-73-9",100,95.49,"<1",0,"https://www.selleckchem.com/products/pasireotide.html","C58H66N10O9","Free base","SOM230","NCCCCC1NC(=O)C(CC2=C[NH]C3=CC=CC=C23)NC(=O)C(NC(=O)C4CC(CN4C(=O)C(CC5=CC=CC=C5)NC(=O)C(CC6=CC=C(OCC7=CC=CC=C7)C=C6)NC1=O)OC(=O)NCCN)C8=CC=CC=C8",3.721,9,9,18]
["S4684","Sildenafil","d4","L1300-36","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017,IP2010","077342,078380,091378,091379,091448,091479,200149,200165,201150,201171,202023,202025,202255,202503,202506,202597,202598,202659,203623,203814,203962,203963,203988,204882,204883,206401,207178,208494,210394,212051,212260","Cardiovascular Disease","PDE","Metabolism","Sildenafil (Revatio, UK-92480, Viagra) is a Phosphodiesterase 5 Inhibitor with IC50 of 5.22 nM.",474.58,"139755-83-2",0,">10",0,0,"http://selleckchem.com/products/sildenafil.html","C22H30N6O4S","free base","Revatio, UK-92480, Viagra","CCCC1=N[N](C)C2=C1N=C(NC2=O)C3=CC(=CC=C3OCC)[S](=O)(=O)N4CCN(C)CC4",2.247,6,1,7]
["S3591","Eprinomectin","e4","L1300-36","in 10mM DMSO","EMA, HMA","USP36-NF31, USP35-NF30 S1, USP35-NF30",null,"Infection","Parasite","Microbiology","Eprinomectin (EPM, MK-397) is an excellent broad-spectrum endectocide with anthelmintic, insecticidal and miticidal activity.",914.13,"123997-26-2",100,109.39363,"<1",0,"https://www.selleckchem.com/products/eprinomectin.html","N/A","Free Base","EPM, MK-397",0,0,0,0,0]
["S1634","Acetaminophen","f4","L1300-36","in 10mM DMSO","NDC, PMDA, DMF",null,"M012","Immune system","COX","Neuronal Signaling","Acetaminophen is a COX inhibitor for COX-1 and COX-2 with IC50 of 113.7 μM and 25.8 μM, respectively.",151.16,"103-90-2",30,198.4652,13,86.001588,"https://www.selleckchem.com/products/acetaminophen.html","C8H9NO2","Free Base","Paracetamol, Tylenol, APAP","CC(=O)Nc1ccc(O)cc1",0.708,1,2,1]
["S0718","AG-120 (racemic)","g4","L1300-36","in 10mM DMSO","FDA",null,null,"Cancer","Dehydrogenase","Metabolism","AG-120 (racemic), the racemic mixture of AG-120, is an orally available inhibitor of <b>isocitrate dehydrogenase type 1 (IDH1) with potential antineoplastic activity.",582.96,"1448346-63-1",100,171.53836,"<1",0,"https://www.selleckchem.com/products/ag-120--racemic-.html","C28H22ClF3N6O3","free base","N/A","Fc1cncc(c1)N(C(C(=O)NC2CC(F)(F)C2)c3ccccc3Cl)C(=O)C4CCC(=O)N4c5cc(ccn5)C#N",3.004,5,1,7]
["E1243","Azvudine","h4","L1300-36","in 10mM DMSO","CFDA",null,null,"Infection","HIV Protease","Microbiology","Azvudine (RO-0622) is a novel nucleoside reverse transcriptase inhibitor with antiviral activity against <b>human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV)</b>, potently inhibits <b>HIV-1</b> (EC50 range 0.03 to 6.92 nM) and <b>HIV-2</b> (EC50s ranging from 0.018 to 0.025 nM).",286.22,"1011529-10-4",57,199.14751,57,199.14751,"https://www.selleckchem.com/products/azvudine","C9H11FN6O4","Free base","RO-0622","[NH2:20][C:16]1=[N:15][C:14](=[O:19])[N:13]([CH:18]=[CH:17]1)[CH:4]2[O:5][C:1]([CH2:6][OH:11])([N:7]=[N+:8]=[N-:9])[CH:2]([OH:10])[CH:3]2[F:12]",-0.544,4,3,3]
["E1796","Dimethindene maleate","a5","L1300-36","in 10mM DMSO","HMA","BP2024;EP11.0;Martindale: The Complete Drug Reference",null,"Inflammation/Immunology","Histamine Receptor","Neuronal Signaling","Dimethindene maleate is a selective antagonist of <b>histamine H1</b> and exhibits antihistamine effects. It suppresses the cromakalim-induced/glibenclamide-sensitive K+ currents in a concentration-dependent and reversible manner.",408.49,"3614-69-5",82,200.73931,9,22.032363,"https://www.selleckchem.com/products/dimethindene-maleate","C20H24N2.C4H4O4","maleate",0,"[CH3:2][CH:1]([C:17]1=[CH:18][CH:20]=[CH:22][CH:21]=[N:19]1)[C:8]2=[C:10]([CH2:3][CH2:4][N:5]([CH3:6])[CH3:7])[CH2:13][C:11]3=[CH:14][CH:16]=[CH:15][CH:12]=[C:9]23.[OH:27][C:25](=[O:28])\\[CH:23]=[CH:24]/[C:26]([OH:29])=[O:30]",1.055,3,0,7]
["S1228","Idarubicin HCl","b5","L1300-36","in 10mM DMSO","HMA,FDA,NDC,DMF,PMDA,CFDA","JP18;USP-NF2024;Martindale: The Complete Drug Reference","050734,065036,065275,065288 ","Cancer/Infection","Topoisomerase","DNA Damage/DNA Repair","Idarubicin HCl (4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl) is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a <b>DNA topoisomerase II (topo II)</b> inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL in a cell-free assay. Idarubicin induces mTOR-dependent cytotoxic <b>autophagy</b>.",533.95,"57852-57-0",100,187.28345,5,9.3641727,"https://www.selleckchem.com/products/Idarubicin","C26H27NO9.HCl","hydrochloride","4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl","[ClH:37].[CH3:11][CH:35]1[O:33][CH:31]([CH2:32][CH:34]([NH2:10])[CH:36]1[OH:12])[O:1][CH:15]2[CH2:19][C:22]([OH:7])([CH2:18][C:14]3=[C:13]2[C:16](=[C:20]4[C:23](=[O:8])[C:25]5=[CH:27][CH:29]=[CH:30][CH:28]=[C:26]5[C:24](=[O:9])[C:21]4=[C:17]3[OH:3])[OH:2])[C:4]([CH3:5])=[O:6]",1.026,5,4,3]
["S6938","Opicapone","c5","L1300-36","in 10mM DMSO","EMA,FDA,NDC,DMF,PMDA",null,"005782,002790,212489","Neurological Disease","Others","Neuronal Signaling","Opicapone(BIA 9-1067) is a potent inhibitor of <b>catechol-O-methyltransferase (COMT)</b> with ED50 values of 1.4 mg⋅kg<sup>−1</sup> in rat erythrocytes. It has the potential to be used in research of Parkinson's disease and motor fluctuations.",413.17,"923287-50-7",83,200.88583,0,0,"https://www.selleckchem.com/products/opicapone","C15H10Cl2N4O6","Free base","BIA 9-1067","[CH3:1][C:17]1=[C:19]([Cl:3])[C:21](=[N:20](=[O:4])[C:18](=[C:16]1[C:11]2=[N:13][O:15][C:14](=[N:12]2)[C:22]3=[CH:23][C:25](=[C:27]([OH:10])[C:26](=[CH:24]3)[OH:9])[N:6](=[O:7])=[O:8])[Cl:2])[CH3:5]",2.867,3,2,3]
["P1094","Degarelix acetate","d5","L1300-36","in 10mM DMSO","EMA,FDA,DMF,PMDA,CFDA","Martindale: The Complete Drug Reference","006048,022201 ","Cancer","Others","Endocrinology & Hormones","Degarelix acetate (ASP-3550 acetate) is a potent and long-acting <b>luteinizing hormone-releasing hormone (LHRH)</b> antagonist.","1632.26(free base)","934016-19-0",100,61.264749,100,61.264749,"https://www.selleckchem.com/products/degarelix-acetate","C82H103ClN18O16.C2H4O2","Free base",0,"[CH3:19][CH:15]([CH3:20])[CH2:12][CH:8]([NH:11][C:14](=[O:18])[CH:17]([CH2:22][C:78]1=[CH:79][CH:81]=[C:83]([NH:63][C:64]([NH2:65])=[O:66])[CH:82]=[CH:80]1)[NH:23][C:26](=[O:28])[CH:27]([CH2:29][C:84]2=[CH:85][CH:87]=[C:89]([NH:67][C:68](=[O:69])[CH:90]3[CH2:91][C:93](=[O:70])[NH:95][C:94](=[O:71])[NH:92]3)[CH:88]=[CH:86]2)[NH:30][C:31](=[O:33])[CH:32]([CH2:35][OH:37])[NH:34][C:36](=[O:39])[CH:38]([CH2:40][C:96]4=[CH:98][N:100]=[CH:101][CH:99]=[CH:97]4)[NH:41][C:42](=[O:44])[CH:43]([CH2:45][C:102]5=[CH:103][CH:105]=[C:107]([Cl:72])[CH:106]=[CH:104]5)[NH:46][C:47](=[O:49])[CH:48]([CH2:50][C:108]6=[CH:109][C:111]7=[C:113]([CH:115]=[CH:117][CH:116]=[CH:114]7)[CH:112]=[CH:110]6)[NH:51][C:52]([CH3:53])=[O:54])[C:6](=[O:9])[NH:4][CH:2]([CH2:5][CH2:7][CH2:10][CH2:13][NH:16][CH:21]([CH3:24])[CH3:25])[C:1](=[O:3])[N:73]8[CH2:75][CH2:77][CH2:76][CH:74]8[C:55](=[O:57])[NH:56][CH:58]([CH3:60])[C:59]([NH2:61])=[O:62]",1.49,16,17,41]
["S1383","Minoxidil","e5","L1300-36","in 10mM DMSO","HMA,FDA,NDC,DMF,CFDA","BP2024;USP-NF2024;EP11.0;IP2010;Martindale: The Complete Drug Reference","071344,071345,019501,071826,071839,072709,074588,075598,091344,075357,209074,075518","Cardiovascular Disease/Cancer","Potassium Channel","Transmembrane Transporters","Minoxidil (U-10858) is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth. Minoxidil is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth.",209.25,"38304-91-5",10,47.789725,"<1",0,"https://www.selleckchem.com/products/Minoxidil","C9H15N5O","Free base","U-10858","[NH2:1][C:7]1=[CH:5][C:4](=[N:6][C:8](=[N:9]1=[O:3])[NH2:2])[N:10]2[CH2:11][CH2:13][CH2:15][CH2:14][CH2:12]2",0.392,1,2,1]
["S1037","Perifosine (KRX-0401)","a2","L1300-37","in 10mM Water","DMF",null,null,"Cancer","Akt","PI3K/Akt/mTOR","Perifosine (KRX-0401, NSC639966, D21266) is a novel Akt inhibitor with IC50 of 4.7 μM in MM.1S cells, targets pleckstrin homology domain of Akt. Phase 3.",461.66,"157716-52-4","<1",0,8,17.33,"http://selleckchem.com/products/Perifosine.html","C25H52NO4P","free base","NSC639966, D21266","CCCCCCCCCCCCCCCCCCO[P]([O-])(=O)OC1CC[N+](C)(C)CC1",4.607,2,0,20]
["S1116","Palbociclib (PD-0332991) HCl","b2","L1300-37","in 10mM Water","FDA,DMF,EMA,NDC,PMDA",null,"207103","Cancer","CDK","Cell Cycle","Palbociclib (PD-0332991) HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays, respectively. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.",483.99,"827022-32-2",3,6.2,30,61.98,"http://selleckchem.com/products/PD-0332991.html","C24H29N7O2.HCl","Hydrochloride","N/A","Cl.CC(=O)C1=C(C)C2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2N(C5CCCC5)C1=O",3.183,5,2,5]
["S1135","Pemetrexed (LY-231514) disodium","c2","L1300-37","in 10mM Water","FDA,DMF,EMA,HMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia","090352,090384,203485,203774,204890,208696,208927,209851,210661","Cancer/Respiratory Disease","Apoptosis related,Autophagy,DHFR,DNA/RNA Synthesis,Thymidylate Synthase","Metabolism","Pemetrexed (LY-231514) disodium is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM in cell-free assays, respectively. Pemetrexed induces autophagy and apoptosis.",471.37,"150399-23-8","<1",0,94,199.42,"http://selleckchem.com/products/Pemetrexed-disodium.html","C20H19N5Na2O6","Disodium salt","LY-231514 disodium","[Na+].[Na+].NC1=NC(=O)C2=C([NH]C=C2CCC3=CC=C(C=C3)C(=O)NC(CCC([O-])=O)C([O-])=O)N1",-1.804,3,4,9]
["S1149","Gemcitabine (LY-188011) HCl","d2","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","077983,078339,078433,078759,079160,079183,090242,090242,090663,090799,091365,091594,091597,200145,200795,202031,202063,202485,202997,204520,204549,205242,206776,207575,209077,209604,210383","Cancer/Respiratory Disease","Autophagy,DNA/RNA Synthesis,Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Gemcitabine (LY-188011, NSC 613327) HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.",299.66,"122111-03-9","<1",0,19,63.41,"http://selleckchem.com/products/Gemcitabine-Hydrochloride(Gemzar).html","C9H11F2N3O4.HCI","Hydrochloride","NSC 613327,LY-188011 HCl","Cl.NC1=NC(=O)N(C=C1)C2OC(CO)C(O)C2(F)F",-1.012,3,3,2]
["S1311","Pamidronate Disodium","e2","L1300-37","in 10mM Water","FDA,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP39-NF34","021113,075290,075594,075773,075841,076153,076207,077433,077703,078156,078300,078373,078520,078942","Others","Others","Others","Pamidronate Disodium (CGP 23339AE) is a nitrogen containing bisphosphonate, used to prevent osteoporosis.",279.03,"57248-88-1","<1",0,56,200.7,"http://selleckchem.com/products/Pamidronate-Disodium.html","C3H9NNa2O7P2","Disodium salt","CGP 23339AE","[Na+].[Na+].NCCC(O)([P](O)([O-])=O)[P](O)([O-])=O",-5.016,0,1,4]
["S1338","Gabapentin HCl","f2","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,BP2017","075350,075360,075428,075435,075477,075485,075539,075694,075827,076017,076120,076403,076537,076605,076606,076672,076877,077242,077261,077525,077661,077662,077894,078150,078428,078782,078787,078926,078974,090007,090158,090335,090705,090858,091008,091286,200651,202024,202764,203244,203611,204989,205101,205807,206402,206943,207057,207099,209306,211314","Neurological Disease","GABA Receptor","Neuronal Signaling","Gabapentin HCl(Neurontin HCl) is a GABA analogue, used to treat seizures and neuropathic pain.",207.7,"60142-95-2","<1",0,42,202.21,"http://selleckchem.com/products/Gabapentin.html","C9H17NO2.HCl","Hydrochloride","Neurontin HCl","Cl.NCC1(CCCCC1)CC(O)=O",-1.104,1,1,3]
["S1339","Galanthamine HBr","g2","L1300-37","in 10mM Water","DMF,CFDA",null,null,"Neurological Disease","AChR,ADC Cytotoxin","Neuronal Signaling","Galanthamine is an AChE inhibitor with IC50 of 0.35 μM, exhibits 50-fold selectivity against butyryl-cholinesterase.",368.27,"1953-04-4","<1",0,36,97.75,"http://selleckchem.com/products/Galanthamine-hydrobromide.html","C17H21NO3.HBr","Hydrobromide","N/A","Br.COC1=CC=C2CN(C)CCC34C=CC(O)CC3OC1=C24",1.933,2,1,1]
["S1345","Granisetron HCl","h2","L1300-37","in 10mM Water","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,EP9.1,BP2017","077177,077186,077187,077297,077842,077913,077963,078037,078080,078090,078197,078198,078221,078258,078260,078262,078392,078522,078531,078534,078564,078565,078566,078629,078678,078725,078808,078835,078843,078846,078863,078880,078969,079078,079119,090817,091136,091137,091274,203453,203454,204238","Gastroenterology","5-HT Receptor","Neuronal Signaling","Granisetron is a serotonin 5-HT3 receptor antagonist,used to treat chemotherapy-induced nausea and vomiting.",348.87,"107007-99-8",1,2.87,69,197.78,"http://selleckchem.com/products/Granisetron-Hydrochloride.html","C18H24N4O.HCl","Hydrochloride","N/A","Cl.CN1C2CCCC1CC(C2)NC(=O)C3=N[N](C)C4=CC=CC=C34",2.783,2,1,2]
["S1370","Biapenem","a3","L1300-37","in 10mM Water","CFDA,PMDA","Martindale:The Extra Pharmacopoeia",null,"Infection","Antibiotics,Bacterial","Microbiology","Biapenem (L-627, LJC10627) is a carbapenem antibiotic with activity against both Gram-positive and Gram-negative bacterial strains.",350.39,"120410-24-4","<1",0,16,45.66,"http://selleckchem.com/products/Biapenem.html","C15H18N4O4S","free base","L-627, LJC10627","CC(O)C1C2C(C)C(=C(N2C1=O)C([O-])=O)SC3C[N]4C=NC=[N+]4C3",-2.248,2,1,4]
["S1375","Dorzolamide HCl","b3","L1300-37","in 10mM Water","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017","077846,078395,078748,078756,078981,079186,090143,091034,202053,205294","Ophthalmology","Carbonic Anhydrase","Metabolism","Dorzolamide (MK-507, L-671152) HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent.",360.9,"130693-82-2","<1",0,14,38.79,"http://selleckchem.com/products/Dorzolamide-HCL.html","C10H16N2O4S3.HCl","Hydrochloride","MK-507 (L-671152) HCl","Cl.CCNC1CC(C)[S](=O)(=O)C2=C1C=C(S2)[S](N)(=O)=O",0.527,4,2,3]
["S1384","Mizoribine","c3","L1300-37","in 10mM Water","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Immunology","DNA/RNA Synthesis,HCV","DNA Damage/DNA Repair","Mizoribine (Bredinin, NSC 289637,HE 69) is an imidazole nucleoside and an immunosuppressant that inhibits HCV RNA replication with IC50 of ~ 100 μM for anti-HCV activity. Mizoribine is a selective inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH) and guanosine monophosphate synthetase. Mizoribine also inhibits SARS-CoV.",259.22,"50924-49-7",1,3.86,51,196.74,"http://selleckchem.com/products/Mizoribine.html","C9H13N3O6","free base","Bredinin, NSC 289637,HE 69","NC(=O)C1=C(O)[N](C=N1)C2OC(CO)C(O)C2O",-2.409,3,5,3]
["S1395","Polymyxin B sulphate","d3","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC","BP2015","062036","Infection","Antibiotics,Antibiotics for Mammalian Cell Culture,Antineoplastic and Immunosuppressive Antibiotics","Microbiology","Polymyxin B (Aerosporin, PMB, Poly-RX) is an antibiotic primarily used for resistant gram-negative infections.",1301.56,"1405-20-5, 4135-11-9 (free base)","<1",0,100,76.83,"http://selleckchem.com/products/Polymyxin-B-sulphate.html","C56H98N16O13.H2SO4","sulfate","Aerosporin, PMB, Poly-RX","CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCN)NC1=O)C(C)O.O[S](O)(=O)=O",-6.873,11,18,29]
["S1399","Teicoplanin","e3","L1300-37","in 10mM Water","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.8,KP Ⅹ,JP17,BP2017",null,"Infection","Antibiotics,Bacterial","Microbiology","Teicoplanin (Teichomycin,Targocid,MDL-507) is a glycopeptide antibiotic, used to treat serious infections caused by Gram-positive bacteria.",1709.39,"61036-62-2","<1",0,100,58.5,"http://selleckchem.com/products/Teicoplanin.html","C77H77N9O31Cl2.R","free base","Teichomycin,Targocid,MDL-507","CCCCCCCCCC(C)=O.CCCCC\\C=C\\CCC(C)=O.CCC(C)CCCCCCC(C)=O.CC(C)CCCCCCCC(C)=O.CC(C)CCCCCCC(C)=O.CC(=O)NC1C(O)C(O)C(CO)OC1OC2C3NC(=O)C(NC(=O)C4NC(=O)C5NC(=O)C(CC6=CC=C(OC7=C(OC8OC(CO)C(O)C(O)C8N[R])C(=CC4=C7)OC9=C(Cl)C=C2C=C9)C(=C6)Cl)NC(=O)C(N)C%10=CC(=C(O)C=C%10)OC%11=CC5=CC(=C%11)O)C%12=CC(=C(O)C=C%12)C%13=C(OC%14OC(CO)C(O)C(O)C%14O)C=C(O)C=C%13C(NC3=O)C(O)=O",14.847,22,23,50]
["S1440","Varenicline Tartrate (CP 526555-18)","f3","L1300-37","in 10mM Water","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia","201808","Psychotic disorders","AChR","Neuronal Signaling","Varenicline Tartrate (CP 526555-18, Chantix, Champix) is a nicotinic AChR partial agonist, used to treat nicotine addiction.",361.35,"375815-87-5",1,2.77,72,199.25,"http://selleckchem.com/products/Varenicline-tartrate.html","C13H13N3.C4H6O6","Tartrate","Chantix, Champix,CP 526555-18","OC(C(O)C(O)=O)C(O)=O.C1NCC2CC1C3=C2C=C4N=CC=NC4=C3",-3.33,4,3,3]
["S1506","Perindopril Erbumine","g3","L1300-37","in 10mM Water","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017","078138,078263,079070,090072,090463","Cardiovascular Disease","RAAS","Endocrinology & Hormones","Perindopril Erbumine (S9490-3) is a pro-drug and metabolized in vivo by hydrolysis of the ester group to form Perindoprilat, the biologically active metabolite, a potent ACE inhibitor with IC50 of 1.05 nM. Perindopril Erbumine is used for in vivo studies and Perindoprilat is recommened for in vitro research.",441.6,"107133-36-8","<1",0,88,199.28,"http://selleckchem.com/products/Perindopril-Erbumine(Aceon).html","C19H32N2O5.C4H11N","t-Butylamine","S9490-3","CCCC(NC(C)C(=O)N1C2CCCCC2CC1C(O)=O)C(=O)OCC.CC(C)(C)N",0.016,4,2,9]
["S1516","Cidofovir","h3","L1300-37","in 10mM Water","FDA,DMF,EMA,HMA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","201276,202501","Inflammation","CMV,DNA/RNA Synthesis","DNA Damage/DNA Repair","Cidofovir (HPMPC,Vistide,GS 0504) suppresses virus replication by selective inhibition of viral DNA synthesis.",279.19,"113852-37-2",2,7.16,12,42.98,"http://selleckchem.com/products/Cidofovir.html","C8H14N3O6P","Free Base","HPMPC,Vistide,GS 0504","NC1=NC(=O)N(CC(CO)OC[P](O)(O)=O)C=C1",-2.175,3,2,6]
["S1518","Ibuprofen Lysine","a4","L1300-37","in 10mM Water","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia","202402","Neurological Disease/Inflammation","COX","Neuronal Signaling","Ibuprofen Lysine is a non-steroidal anti-inflammatory drug.",352.47,"57469-77-9","<1",0,71,201.44,"http://selleckchem.com/products/Ibuprofen-Lysine(Motrin).html","C19H32N2O4","Lysine","N/A","CC(C)CC1=CC=C(C=C1)C(C)C(O)=O.NCCCCC(N)C(O)=O",-2.112,2,2,9]
["S1579","Palbociclib (PD0332991) Isethionate","b4","L1300-37","in 10mM Water","FDA,DMF,EMA,NDC,PMDA",null,"207103","Cancer","CDK","Cell Cycle","Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.",573.66,"827022-33-3","<1",0,10,17.43,"http://selleckchem.com/products/pd-0332991-palbociclib-isethionate.html","C24H29N7O2.C2H6O4S","Isethionate","N/A","CC(=O)C1=C(C)C2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2N(C5CCCC5)C1=O.OCC[S](O)(=O)=O",1.847,5,3,7]
["S1624","Alendronate sodium trihydrate","c4","L1300-37","in 10mM Water","DMF","Martindale:The Extra Pharmacopoeia,EP9.0,USP39-NF34",null,"Metabolic Disease","Others","Metabolism","Alendronate sodium trihydrate (G-704650, MK-217), a nitrogen-containing bisphosphonate, is a potent inhibitor of bone resorption used for the treatment and prevention of osteoporosis.",326.13,"121268-17-5","<1",0,20,61.33,"http://selleckchem.com/products/Alendronate-Sodium(Fosamax).html","C4H13NO7P2.3H2O.Na","Sodium Salt","G-704650, MK-217","O.O.O.NCCCC(O)([P](O)(O)=O)[P](O)(=O)O[Na]",0,0,0,0]
["S1648","Cytarabine (U-19920A)","d4","L1300-37","in 10mM Water","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","016793,071248,071249,071471,071472,071868,072168,072945,074245,075383,076512,200914,200915,200916,201784,205696,206190","Cancer/Hematology","Apoptosis related,Autophagy,DNA/RNA Synthesis,Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Cytarabine (Cytarabin, Ara-C, Arabinofuranosyl Cytidine, Cytosine β-D-arabinofuranoside, Cytosine arabinoside, NSC 63878, NSC 287459,U-19920A) is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM in wild-type CCRF-CEM cells. Cytarabine induces autophagy and apoptosis.",243.22,"147-94-4",1,4.11,48,197.35,"http://selleckchem.com/products/Cytarabine(Cytosar-U).html","C9H13N3O5","free base","Cytarabin,Ara-C,Arabinofuranosyl Cytidine,Cytosine β-D-arabinofuranoside,Cytosine arabinoside,NSC 63878,NSC 287459,U-19920A","NC1=NC(=O)N(C=C1)C2OC(CO)C(O)C2O",-2.396,3,4,2]
["S1749","L-Glutamine","e4","L1300-37","in 10mM Water","FDA,DMF,NDC,HMA","USP42-NF37,JP17","208587,021667","Hematology","Others","Others","L-Glutamine (Gln) is one of the 20 amino acids encoded by the standard genetic code and also a major respiratory fuel and substrate for nucleic acid synthesis in mammalian intestinal cells.",146.14,"56-85-9","<1",0,29,198.44,"http://selleckchem.com/products/Glutamine.html","C5H10N2O3","free base","N/A","NC(CCC(N)=O)C(O)=O",-4.087,2,2,4]
["S1751","Gadodiamide Hydrate","f4","L1300-37","in 10mM Water","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,EP9.1","020123,022066","Diagnosis","Others","Others","Gadodiamide Hydrate, a nonionic Gd3+ chelate, is frequently injected i.v. into magnetic resonance imaging (MRI) to enhance contrast.",591.67,"122795-43-1","<1",0,100,169.01,"http://selleckchem.com/products/Gadodiamide(Omniscan).html","C16H28GdN5O9C16H28GdN5O9.xH2O","Hydrate","N/A","O.[Gd+3].CNC(=O)CN(CCN(CCN(CC([O-])=O)CC(=O)NC)CC([O-])=O)CC([O-])=O",-7.468,2,2,16]
["S1853","Penicillamine","g4","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,Ph.Int_6th,BP2017,IP2010","209921","Immunology/Inflammation/Metabolic Disease","Others","Others","Penicillamine (Dimethyl Cysteine) is used as an antirheumatic and as a chelating agent in Wilson’s disease.",149.21,"52-67-5","<1",0,30,201.06,"http://selleckchem.com/products/Penicillamine(Cuprimine).html","C5H11NO2S","free base","Dimethyl Cysteine","CC(C)(S)C(N)C(O)=O",-2.496,1,1,2]
["S1857","Etidronate","h4","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,JP17,BP2017,USP39-NF34","075800","Inflammation","phosphatase","Metabolism","Etidronate is a non-aminobisphosphonate, show protein tyrosine phosphatase (PTP) inhibitory activity, used for the treatment of Paget's disease and the prevention of heterotopic ossification.",206.03,"2809-21-4","<1",0,41,199,"http://selleckchem.com/products/etidronate-didronel.html","C2H8O7P2","free base","N/A","CC(O)([P](O)(O)=O)[P](O)(O)=O",-0.701,0,0,2]
["S1875","Tranexamic Acid","a5","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","091596,091657,201580,201885,202093,202286,202373,202436,202755,203256,203521,205035,205133,205228,206594,206634,206713,207239,208840,209326,212020","Hematology","Others","Others","Tranexamic Acid(Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.",157.21,"1197-18-8","<1",0,31,197.19,"http://selleckchem.com/products/tranexamic-acid-transamin.html","C8H15NO2","free base","Transamin","NCC1CCC(CC1)C(O)=O",-1.753,1,1,2]
["S1939","Levamisole hydrochloride","b5","L1300-37","in 10mM Water","FDA,CFDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,Ph.Int_6th,BP2017,IP2010","020035","Infection","Immunology & Inflammation related","Immunology & Inflammation","Levamisole, also known as (-)-Tetramisole, is an inhibitor of alkaline phosphatase, used as an anthelmintic.",240.75,"16595-80-5","<1",0,48,199.38,"http://selleckchem.com/products/Levamisole-Hydrochloride(Ergamisol).html","C11H12N2S.HCl","Hydrochloride","(-)-Tetramisole hydrochloride","Cl.C1CN2CC(N=C2S1)C3=CC=CC=C3",2.672,1,0,1]
["S1984","Ticlopidine HCl","c5","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","075089,075149,075161,075253,075309,075316,075318,075326,075526","Cardiovascular Disease","P2 Receptor","Neuronal Signaling","Ticlopidine HCl is an P2 receptor inhibitor against ADP-induced platelet aggregation with IC50 of ~2 μM.",300.25,"53885-35-1",1,3.33,4,13.32,"http://selleckchem.com/products/ticlopidine-hydrochloride.html","C14H14ClNS.HCl","Hydrochloride","N/A","Cl.ClC1=C(CN2CCC3=C(C2)C=CS3)C=CC=C1",4.275,0,0,2]
["S1985","ATP disodium","d5","L1300-37","in 10mM Water","DMF,NDC",null,null,"Others","Others","Others","ATP Disodium (Adenosine-Triphosphate disodium, ATP disodium salt, Adenosine 5'-triphosphate) is a disodium salt form of adenosine-triphosphate which is a multifunctional nucleoside triphosphate.",551.14,"987-65-5","<1",0,100,181.44,"http://selleckchem.com/products/atp-Adenosine-Triphosphate.html","C10H14N5O13P3.2Na","Disodium Salt","Adenosine-Triphosphate disodium, ATP disodium salt, Adenosine 5'-triphosphate","[Na+].[Na+].NC1=NC=NC2=C1N=C[N]2C3OC(CO[P](O)(=O)O[P]([O-])(=O)O[P](O)([O-])=O)C(O)C3O",-5.474,7,3,8]
["S1995","Procarbazine HCl","e5","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,Ph.Int_6th,JP17","016785","Cancer","DNA/RNA Synthesis","DNA Damage/DNA Repair","Procarbazine HCl (NSC-77213) is a hydrochloride salt form of procarbazine which is a polyfunctional alkylating compound, used for the treatment of Hodgkin's lymphoma.",257.76,"366-70-1","<1",0,52,201.74,"http://selleckchem.com/products/procarbazine-hydrochloride-matulane.html","C12H19N3O.HCl","Hydrochloride","NSC-77213 HCl","Cl.CNNCC1=CC=C(C=C1)C(=O)NC(C)C",1.12,1,3,5]
["S1998","D-Cycloserine","f5","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,Ph.Int_6th,JP17,IP2010","060593","Infection/Respiratory Disease","Antibiotics,Selection Antibiotics for Transfected Cell","Microbiology","D-cycloserine (RO-1-9213) is an analog of the amino acid D-alanine, used as an antibiotic in the treatment of tuberculosis.",102.09,"68-41-7","<1",0,20,195.91,"http://selleckchem.com/products/D-Cycloserine.html","C3H6N2O2","free base","RO-1-9213","NC1CONC1=O",-1.788,2,2,0]
["S1999","Sodium butyrate","g5","L1300-37","in 10mM Water","DMF","USP39-NF34",null,"Others","Apoptosis related,Autophagy,HDAC","Epigenetics","Sodium butyrate (NaB, Butanoic acid sodium salt), sodium salt of butyric acid, is a histone deacetylase inhibitor and competitively binds to the zinc sites of class I and II histone deacetylases (HDACs). Sodium butyrate (NaB) inhibits cell cycle progression, promotes differentiation, and induces apoptosis and autophagy in several types of cancer cells.",110.09,"156-54-7","<1",0,22,199.84,"http://selleckchem.com/products/Sodium-butyrate.html","C4H7NaO2","Sodium Salt","NaB, Butanoic acid sodium salt","[Na+].CCCC([O-])=O",-0.556,0,0,2]
["S2008","Taurine","h5","L1300-37","in 10mM Water","DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,JP16",null,"Nutritional support","Others","Others","Taurine is an organic acid widely distributed in animal tissues.",125.15,"107-35-7","<1",0,20,159.81,"http://selleckchem.com/products/Taurine.html","C2H7NO3S","free base","N/A","NCC[S](O)(=O)=O",-1.243,0,1,2]
["S2048","Clindamycin Phosphate","a6","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,Ph.Int_5th","062747,062795,062800,062801,062806,062811,062819,062852,062877,062889,062900,062905,062908,062913,062928,062930,062943,062944,062953,063041,063068,063079,063163,063282,063304,064050,064108,064159,064160,065049,065067,065139,065184,065206,065254,065346,065347,065513,090108,090109,090785,203343,204748,204749,206945,208767,209846,209914","Infection/Parasitology","Antibiotics","Microbiology","Clindamycin Phosphate (NSC 618653) is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM.",504.96,"24729-96-2","<1",0,101,200.02,"http://selleckchem.com/products/clindamycin-phosphate.html","C18H34ClN2O8PS","free base","NSC 618653","CCCC1CC(N(C)C1)C(=O)NC(C(C)Cl)C2OC(SC)C(O[P](O)(O)=O)C(O)C2O",1.205,3,3,9]
["S2076","Lisinopril dihydrate","b6","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017,IP2010","075743,075752,075783,075903,075944,075994,075999,076059,076063,076071,076102,076164,076180,077321,077622,078402,202554,203508","Cardiovascular Disease","ACE,RAAS","Endocrinology & Hormones","Lisinopril dihydrate(MK-521 dihydrate) is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes.",441.52,"83915-83-7","<1",0,20,49.32,"http://selleckchem.com/products/lisinopril-zestril.html","C21H35N3O7","free base","MK-521 dihydrate","NCCCCC(NC(CCC1=CC=CC=C1)C(O)=O)C(=O)N2CCCC2C(O)=O",-3.673,3,2,12]
["S2129","Fudosteine","c6","L1300-37","in 10mM Water","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Immunology/Respiratory Disease","Others","Metabolism","Fudosteine is a cysteine derivative and a MUC5AC mucin hypersecretion inhibitor, used as a muco-active agent with indications for chronic respiratory diseases.",179.24,"13189-98-5","<1",0,36,200.85,"http://selleckchem.com/products/Fudosteine.html","C6H13NO3S","free base","N/A","NC(CSCCCO)C(O)=O",-3.373,1,2,6]
["S2133","Gabapentin","d6","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,BP2017","075350,075360,075428,075435,075477,075485,075539,075694,075827,076017,076120,076403,076537,076605,076606,076672,076877,077242,077261,077525,077661,077662,077894,078150,078428,078782,078787,078926,078974,090007,090158,090335,090705,090858,091008,091286,200651,202024,202764,203244,203611,204989,205101,205807,206402,206943,207057,207099,209306,211314","Neurological Disease","GABA Receptor","Neuronal Signaling","Gabapentin is a GABA analogue, used to treat seizures and neuropathic pain.",171.24,"60142-96-3","<1",0,34,198.55,"http://selleckchem.com/products/Gabapentin(Neurontin).html","C9H17NO2","Free Base","N/A","NCC1(CCCCC1)CC(O)=O",-1.486,1,1,3]
["S2315","Kanamycin sulfate","e6","L1300-37","in 10mM Water","FDA,DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,JP17,BP2017","062466,062504,062520,062605,062642,062668,062669,062672,063021,063022,063025,063092,065111","Infection","Antibiotics,Antibiotics for Mammalian Cell Culture,Antibiotics for Plant Cell Culture,Selection Antibiotics for Transfected Cell","Microbiology","Kanamycin sulfate (Kanamycin monosulfate, Ophtalmokalixan) is an aminoglycoside antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections.",582.58,"25389-94-0","<1",0,52,89.26,"http://selleckchem.com/products/Kanamycin-sulfate(Kantrex).html","C18H38N4O15S","sulfate","Kanamycin monosulfate, Ophtalmokalixan","NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(O)C(O)C1O.O[S](O)(=O)=O",-7.751,4,11,6]
["S2416","Chondroitin sulfate","f6","L1300-37","in 10mM Water","DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017",null,"Inflammation","NF-κB","NF-κB","Chondroitin sulfate (CS) is a major component of the extracellular matrix (ECM) of many connective tissues, including cartilage, bone, skin, ligaments and tendons. It reduces the IL-1β-induced nuclear factor-kB (NF-κB) translocation in chondrocytes in vitro.",489.45,"9007-28-7",0,0,97,198.18,"http://selleckchem.com/products/chondroitin-sulfate.html","(C14H21NO14S)n","sulfate","N/A","COC1OC(CO[S](O)(=O)=O)C(O)C(OC2OC(C(C)C(O)C2O)C(O)=O)C1NC(C)=O",-2.447,7,4,8]
["S2462","Donepezil HCl","g6","L1300-37","in 10mM Water","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,JP17,IP2010","076786,076893,077344,077518,077975,078388,078662,078841,090056,090100,090175,090247,090290,090425,090493,090521,090551,090686,090768,091198,091267,200292,201001,201146,201335,201634,201724,201787,202114,202410,202415,202542,202631,202656,202723,202782,203034,203104,203114,203162,203419,203656,203713,203907,204293,204609,204831,205269","Neurological Disease","AChR","Neuronal Signaling","Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively.",416,"120011-70-3","<1",0,5,12.02,"http://selleckchem.com/products/Donepezil-hydrochloride(Aricept).html","C24H29NO3.HCl","Hydrochloride","N/A","Cl.COC1=C(OC)C=C2C(=O)C(CC3CCN(CC3)CC4=CC=CC=C4)CC2=C1",4.951,3,0,6]
["S2490","Neostigmine Bromide","h6","L1300-37","in 10mM Water","PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,KP Ⅹ,Ph.Int_6th,BP2017,IP2010",null,"Neurological Disease","AChR","Neuronal Signaling","Neostigmine Bromide is a reversible acetylcholinesterase inhibitor.",303.2,"114-80-7","<1",0,60,197.89,"http://selleckchem.com/products/Neostigmine-bromide(Prostigmin).html","C12H19N2O2.Br","Bromide","N/A","[Br-].CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C",-1.907,2,0,3]
["S2507","Salbutamol Sulfate","a7","L1300-37","in 10mM Water","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017",null,"Immunology/Respiratory Disease","Adrenergic Receptor","Neuronal Signaling","Salbutamol Sulfate (Albuterol, Ventolin, Aerolin, Ventorlin, Asthalin, Asthavent) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 µM.",337.39,"51022-70-9","<1",0,68,201.55,"http://selleckchem.com/products/Salbutamol-sulfate(Albuterol).html","C13H21NO3.H2SO4","Sulfate","Albuterol, Ventolin, Aerolin, Ventorlin, Asthalin, Asthavent","CC(C)(C)NCC(O)C1=CC=C(O)C(=C1)CO.O[S](O)(=O)=O",0.334,0,4,5]
["S2514","Tobramycin","b7","L1300-37","in 10mM Water","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,IP2010","063176,064052,065026,065087,091589,201422,205501,207080,207444,208964,209554,210915,211847","Infection","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics","Microbiology","Tobramycin (NSC 180514,Deoxykanamycin B, Nebramycin Factor 6) is an aminoglycoside antibiotic with an IC50 of 9.7 μM.",467.52,"32986-56-4","<1",0,94,201.06,"http://selleckchem.com/products/Tobramycin(free-base).html","C18H37N5O9","free base","NSC 180514,Deoxykanamycin B, Nebramycin Factor 6","NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)CC1O",-6.86,4,10,6]
["S2518","NAD+","c7","L1300-37","in 10mM Water","DMF",null,null,"Others","Others","Others","NAD+ (β-DPN, β-NAD, β-Nicotinamide Adenine Dinucleotide,nicotinamide adenine dinucleotide) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.",663.43,"53-84-9","<1",0,100,150.73,"http://selleckchem.com/products/nad.html","C21H27N7O14P2","free base","β-DPN, β-NAD, β-Nicotinamide Adenine Dinucleotide,nicotinamide adenine dinucleotide","NC(=O)C1=CC=C[N+](=C1)C2OC(CO[P]([O-])(=O)O[P](O)(=O)OCC3OC(C(O)C3O)[N]4C=NC5=C(N)N=CN=C45)C(O)C2O",-4.524,9,6,11]
["S2527","Methacycline HCl","d7","L1300-37","in 10mM Water","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ","060641","Infection","Antibiotics","Microbiology","Methacycline HCl (Rondomycin) is a tetracycline antibiotic, and also an inhibitor of epithelial–mesenchymal transition (EMT) with IC50 of roughly 5 μM, used to treat various infections.",478.88,"3963-95-9",3,6.26,5,10.44,"http://selleckchem.com/products/Methacycline-hydrochloride-Physiomycine.html","C22H22N2O8.HCl","Hydrochloride","Rondomycin","Cl.CN(C)C1C2C(O)C3C(=C)C4=CC=CC(=C4C(=O)C3=C(O)C2(O)C(=O)C(=C1O)C(N)=O)O",-0.565,3,5,2]
["S2539","Lomefloxacin HCl","e7","L1300-37","in 10mM Water","FDA,DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia","020013","Infection","Antibiotics","Microbiology","Lomefloxacin HCl is a hydrochloride salt of lomefloxacin and is a fluoroquinolone antibiotic.",387.81,"98079-52-8",1,2.58,6,15.47,"http://selleckchem.com/products/Lomefloxacin-hydrochloride-Maxaquin.html","C17H19F2N3O3.HCl","Hydrochloride","N/A","Cl.CCN1C=C(C(O)=O)C(=O)C2=CC(=C(N3CCNC(C)C3)C(=C12)F)F",-0.446,2,1,3]
["S2560","Amiloride HCl dihydrate","f7","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,Ph.Int_6th,BP2017,IP2010","070346,079133,204180","Cardiovascular Disease/Metabolic Disease","Sodium Channel","Transmembrane Transporters","Amiloride HCl dihydrate(MK-870 hydrochloride dihydrate) is a potent epithelial sodium channel (ENaC) blocker, used in the management of hypertension and congestive heart failure.",302.12,"17440-83-4",0,0,17,56.27,"http://selleckchem.com/products/amilorida.html","C6H8ClN7O.HCl.2H2O","hydrochloride & dihydrate","MK-870 hydrochloride dihydrate","O.O.Cl.NC(=N)NC(=O)C1=NC(=C(N)N=C1N)Cl",-0.78,3,4,2]
["S2563","Oxacillin sodium monohydrate","g7","L1300-37","in 10mM Water","DMF","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017",null,"Infection","Antibiotics,Bacterial","Microbiology","Oxacillin sodium monohydrate (Methicillin) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.",441.43,"7240-38-2","<1",0,88,199.35,"http://selleckchem.com/products/Oxacillin-sodium-monohydrate.html","C19H18N3O5S.Na.H2O","Sodium Salt & hydrate","Methicillin","O.[Na+].CC1=C(C(=O)NC2C3SC(C)(C)C(N3C2=O)C([O-])=O)C(=NO1)C4=CC=CC=C4",-0.046,4,1,4]
["S2568","Neomycin sulfate","h7","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP35-NF30","060304,060365,060385,060607,061586,062173,065220,065468,204435","Infection","Antibiotics,Antibiotics for Mammalian Cell Culture,Antineoplastic and Immunosuppressive Antibiotics,Bacterial,Selection Antibiotics for Transfected Cell","Microbiology","Neomycin sulfate(Framycin sulfate) is an aminoglycoside antibiotic, used to treat bacteria infections.",712.72,"28002-70-2 ,1405-10-3","<1",0,143,200.64,"http://selleckchem.com/products/Neomycin-sulfate.html","C23H46N6O13.H2SO4","Sulfate","Framycin sulfate","NCC1OC(OC2C(N)CC(N)C(O)C2OC3OC(CO)C(OC4OC(CN)C(O)C(O)C4N)C3O)C(N)C(O)C1O.O[S](O)(=O)=O",-9.566,6,13,9]
["S2572","Streptomycin sulfate","a8","L1300-37","in 10mM Water","FDA,DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,KP Ⅹ,Ph.Int_6th,JP17,BP2017","060076,060107,060111,060404,060684,064210","Infection/Respiratory Disease","Antibiotics for Plant Cell Culture,Anti-infection,Selection Antibiotics for Transfected Cell","Microbiology","Streptomycin sulfate(Phytomycin) is a sulfate salt of streptomycin that is a protein synthesis inhibitor.",1457.38,"3810-74-0","<1",0,89,61.07,"http://selleckchem.com/products/streptomycin-sulfate.html","2C21H39N7O12.3H2SO4","1.5 Sulfate","Phytomycin","CNC1C(O)C(O)C(CO)OC1OC2C(OC(C)C2(O)C=O)OC3C(O)C(O)C(NC(N)=N)C(O)C3NC(N)=N.CNC4C(O)C(O)C(CO)OC4OC5C(OC(C)C5(O)C=O)OC6C(O)C(O)C(NC(N)=N)C(O)C6NC(N)=N.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O",-14.403,10,22,22]
["S2575","Vancomycin HCl","b8","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8,KP Ⅹ,JP17,BP2017,IP2010","062845,062663,062879,062911,062912,062931,062933,063076,065397,065401,065432,065453,065455,065478,065490,065510,090250,090439,091377,091469,091554,200837,201048,201250,201251,202274,202275,202464,204107,204125,204360,205694,205779,205780,206243,206616,209481,210729,211962","Infection/Inflammation","Bacterial","Microbiology","Vancomycin HCl is a hydrochloride of vancomycin that is a narrow-spectrum glycopeptide antibacterial agent.",1485.71,"1404-93-9","<1",0,100,67.31,"http://selleckchem.com/products/vancomycin-hydrochloride-vancocin.html","C66H75Cl2N9O24.HCl","HCl","N/A","Cl.CNC(CC(C)C)C(=O)NC1C(O)C2=CC=C(OC3=CC4=CC(=C3OC5OC(CO)C(O)C(O)C5OC6CC(C)(N)C(O)C(C)O6)OC7=CC=C(C=C7Cl)C(O)C8NC(=O)C(NC(=O)C4NC(=O)C(CC(N)=O)NC1=O)C9=CC(=C(O)C=C9)C%10=C(C=C(O)C=C%10O)C(NC8=O)C(O)=O)C(=C2)Cl",-2.544,14,18,13]
["S2908","Hygromycin B","c8","L1300-37","in 10mM Water",null,"Martindale:The Extra Pharmacopoeia",null,"Infection","Antibiotics,Antibiotics for Plant Cell Culture,Antineoplastic and Immunosuppressive Antibiotics,Bacterial,Selection Antibiotics for Transfected Cell","Microbiology","Hygromycin B (Hygrovetine), a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.",527.52,"31282-04-9","<1",0,100,189.57,"http://selleckchem.com/products/hygromycin-b.html","C20H37N3O13","free base","Hygrovetine","CNC1CC(N)C(O)C(OC2OC(CO)C(O)C3OC4(OC(C(N)CO)C(O)C(O)C4O)OC23)C1O",-5.97,5,11,6]
["S3007","Zanamivir","d8","L1300-37","in 10mM Water","FDA,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","021036","Infection","Influenza Virus,Neuraminidase","Microbiology","Zanamivir (GG167,GR 121167X) is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus.",332.31,"139110-80-8",2,6.02,25,75.23,"http://selleckchem.com/products/zanamivir-relenza.html","C12H20N4O7","free base","GG167,GR 121167X","CC(=O)NC1C(NC(N)=N)C=C(OC1C(O)C(O)CO)C(O)=O",-3.395,3,6,7]
["S3013","Plerixafor (AMD3100) 8HCl","e8","L1300-37","in 10mM Water","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","022311","Immunology","CXCR,HIV","GPCR & G Protein","Plerixafor (AMD3100, JM 3100,Plerixafor Octahydrochloride,AMD3100 octahydrochloride,SID791 octahydrochloride) 8HCl is the hydrochloride of Plerixafor, a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively. Plerixafor can be used as an anti-HIV agent.",794.47,"155148-31-5","<1",0,100,125.87,"http://selleckchem.com/products/plerixafor-8hcl-db06809.html","C28H54N8.8HCl","Octahydrochloride","JM 3100 8HCl,Plerixafor Octahydrochloride,AMD3100 octahydrochloride,SID791 octahydrochloride","Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl.C1CNCCNCCCN(CCNC1)CC2=CC=C(CN3CCCNCCNCCCNCC3)C=C2",2.536,0,6,4]
["S3028","Geneticin (G418 Sulfate)","f8","L1300-37","in 10mM Water",null,"USP42-NF37",null,"Infection","Antibiotics,Antibiotics for Plant Cell Culture,Antineoplastic and Immunosuppressive Antibiotics,Selection Antibiotics for Transfected Cell","Microbiology","Geneticin (G418 Sulfate), an aminoglycoside antibiotic, is an elongation inhibitor of 80 S ribosomes that blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.",692.71,"108321-42-2","<1",0,100,144.36,"http://selleckchem.com/products/geneticin-g418-sulfate.html","C20H40N4O10.2H2SO4","Disulfate","N/A","CNC1C(O)C(OCC1(C)O)OC2C(N)CC(N)C(OC3OC(C(C)O)C(O)C(O)C3N)C2O.O[S](O)(=O)=O.O[S](O)(=O)=O",-6.833,4,9,6]
["S3048","Solifenacin succinate","g8","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.3,BP2017","091464,202551,205483,205575,206817,207721,209239,209333,209719,209818,209839,210224,210281,210582,210688,211423,211657","Others","AChR","Neuronal Signaling","Solifenacin succinate (YM905) is a urinary antispasmodic of the antimuscarinic class.",480.55,"242478-38-2",3,6.24,96,199.77,"http://selleckchem.com/products/solifenacin-succinate.html","C23H26N2O.C4H6O4","Succinate","YM905","OC(=O)CCC(O)=O.O=C(OC1CN2CCC1CC2)N3CCC4=C(C=CC=C4)C3C5=CC=CC=C5",0.635,4,0,6]
["S3050","Palonosetron HCl","h8","L1300-37","in 10mM Water","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","090713,201533,202521,203050,204289,204702,204731,205648,205870,206396,206416,206801,206802,207005,207364,207963,208109,209287","Gastroenterology","5-HT Receptor","Neuronal Signaling","Palonosetron HCl (RS 25259, RS 25259 197) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.",332.87,"135729-62-3","<1",0,67,201.28,"http://selleckchem.com/products/palonosetron-hcl.html","C19H24N2O.HCl","HCL","RS 25259, RS 25259 197","Cl.O=C1N(CC2CCCC3=CC=CC1=C23)C4CN5CCC4CC5",3.127,1,0,1]
["S3056","Miltefosine","a9","L1300-37","in 10mM Water","FDA,NDC","Martindale:The Extra Pharmacopoeia","204684","Parasite","Akt","PI3K/Akt/mTOR","Miltefosine (Hexadecylphosphocholine) inhibits PI3K/Akt activity with ED50 of 17.2 μM and 8.1 μM in carcinoma cell lines A431 and HeLa, first oral drug for Visceral leishmaniasis, effective against both promastigotes and amastigotes.",407.57,"58066-85-6","<1",0,81,198.74,"http://selleckchem.com/products/miltefosine-hexadecylphosphocholine.html","C21H46NO4P","free base","Hexadecylphosphocholine","CCCCCCCCCCCCCCCCO[P]([O-])(=O)OCC[N+](C)(C)C",3.722,2,0,20]
["S3058","Danofloxacin Mesylate","b9","L1300-37","in 10mM Water",null,"Martindale:The Extra Pharmacopoeia",null,"Infection","Bacterial","Microbiology","Danofloxacin (CP-76136-27) is a fluoroquinolone antibacterial for veterinary use, with MIC90 of 0.28 μM.",453.48,"119478-55-6","<1",0,91,200.67,"http://selleckchem.com/products/danofloxacin-mesylate.html","C19H20FN3O3.CH4O3S","Mesylate","CP-76136-27","CN1CC2CC1CN2C3=CC4=C(C=C3F)C(=O)C(=CN4C5CC5)C(O)=O.C[S](O)(=O)=O",-1.539,2,0,3]
["S3065","Amikacin disulfate","c9","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","063167,063169,063263,063264,063265,063266,063274,063275,063283,063313,063315,063350,064045,064098,064099,203323,204040,205604,205605","Infection","Bacterial","Microbiology","Amikacin sulfate (BB-K8) binds to 16S rRNA (bacterial 30S ribosome), causing misreading of mRNA and supressing proteins synthesis.",781.76,"39831-55-5","<1",0,10,12.79,"http://selleckchem.com/products/amikacin-sulfate.html","C22H43N5O13.2H2SO4","Sulfate","BB-K8","NCCC(O)C(=O)NC1CC(N)C(OC2OC(CN)C(O)C(O)C2O)C(O)C1OC3OC(CO)C(O)C(N)C3O.O[S](O)(=O)=O.O[S](O)(=O)=O",-9.64,5,13,10]
["S3072","(R)-baclofen","d9","L1300-37","in 10mM Water","DMF",null,null,"Neurological Disease","GABA Receptor","Neuronal Signaling","(R)-baclofen (STX 209) is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.",213.66,"69308-37-8","<1",0,8,37.44,"http://selleckchem.com/products/r-baclofen.html","C10H12ClNO2","free base","STX 209","NCC(CC(O)=O)C1=CC=C(Cl)C=C1",-1.06,1,1,4]
["S3073","Caspofungin (MK-0991) Acetate","e9","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia","200833,205923,206110,207092,207650,209489","Infection","Fungal","Microbiology","Caspofungin Acetate (MK-0991, L-743872) is an lipopeptide antifungal β-1,3-glucan synthase inhibitor.",1213.42,"179463-17-3",0,0,100,82.41,"http://selleckchem.com/products/caspofungin-acetate.html","C52H88N10O15.2C2H4O2","diacetate","L-743872","CCC(C)CC(C)CCCCCCCCC(=O)NC1CC(O)C(NCCN)NC(=O)C2C(O)CCN2C(=O)C(NC(=O)C(NC(=O)C3CC(O)CN3C(=O)C(NC1=O)C(C)O)C(O)C(O)C4=CC=C(O)C=C4)C(O)CCN.CC(O)=O.CC(O)=O",-8.482,9,16,23]
["S3102","Creatinine","f9","L1300-37","in 10mM Water","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37",null,"Neurological Disease","Others","Others","Creatinine(NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.",113.12,"60-27-5","<1",0,23,203.32,"http://selleckchem.com/products/creatinine.html","C4H7N3O","free base","NSC13123","CN1CC(=O)NC1=N",-0.9,1,1,0]
["S3122","Amikacin hydrate","g9","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","063167,063169,063263,063264,063265,063266,063274,063275,063283,063313,063315,063350,064045,064098,064099,203323,204040,205604,205605","Infection","Antibiotics,Bacterial,Selection Antibiotics for Transfected Cell","Microbiology","Amikacin(BAY416651 hydrate) is an aminoglycoside antibiotic used to treat different types of bacterial infections.","585.6+x18","1257517-67-1","<1",0,100,10,"http://selleckchem.com/products/amikacin-hydrate.html","C22H43N5O13.xH2O","Hydrate","BAY416651 hydrate","O.NCCC(O)C(=O)NC1CC(N)C(OC2OC(CN)C(O)C(O)C2O)C(O)C1OC3OC(CO)C(O)C(N)C3O",0,0,0,0]
["S3146","Tripelennamine HCl","h9","L1300-37","in 10mM Water","FDA,CFDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","080713,080744,080785,080790,083037,083557,083625,083626,083989,085188,085412","Immunology","Histamine Receptor","Neuronal Signaling","Tripelennamine (Pyribenzamine) is a widely used H1 antagonist, inhibiting PhIP glucuronidation with IC50 of 30 μM.",291.82,"154-69-8",2,6.85,58,198.75,"http://selleckchem.com/products/tripelennamine-hydrochloride.html","C16H21N3.HCl","HCl","Pyribenzamine HCl","Cl.CN(C)CCN(CC1=CC=CC=C1)C2=NC=CC=C2",3.484,1,0,6]
["S3148","Ibandronate sodium monohydrate","a10","L1300-37","in 10mM Water","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,EP","078948,078995,078996,078997,078998,079002,079003,079194,090853,202235,202671,203987,204222,204502,205332,206058,206887","Metabolic Disease","Others","Others","Ibandronate (BM-21.0955, BM-210955, RPR-102289A) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.",360.23,"138926-19-9","<1",0,72,199.87,"http://selleckchem.com/products/ibandronate-sodium.html","C9H23NO7P2.Na.H2O","sodium monohydrate","BM-21.0955, BM-210955, RPR-102289A","O.[NaH].CCCCCN(C)CCC(O)([P](O)(O)=O)[P](O)(O)=O",0.477,0,0,9]
["S3165","Abacavir sulfate","b10","L1300-37","in 10mM Water","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,Ph.Int_6th,BP2017","022293,022547,077844,077950,078119,078348,078742,091050,091294,091560,200733,201107,201570,206725","Infection","Reverse Transcriptase","Microbiology","Abacavir (1592U89) is a commonly used nucleoside analogue with potent antiviral activity against HIV-1.",335.35,"188062-50-2","<1",0,36,107.35,"http://selleckchem.com/products/abacavir-sulfate.html","C14H18N6O.1/2H2SO4","Sulfate","1592U89","NC1=NC2=C(N=C[N]2C3CC(CO)C=C3)C(=N1)NC4CC4.NC5=NC6=C(N=C[N]6C7CC(CO)C=C7)C(=N5)NC8CC8.O[S](O)(=O)=O",0.932,6,6,8]
["S3174","L-Arginine HCl (L-Arg)","c10","L1300-37","in 10mM Water","DMF,CFDA,NDC","JP17,IP2010",null,"Nutritional support","NOS","Immunology & Inflammation","L-Arginine(L-Arg,(S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.",210.66,"1119-34-2","<1",0,42,199.37,"http://selleckchem.com/products/l-Arginine-hydrochloride.html","C6H14N4O2.HCl","HCl","(S)-(+)-Arginine hydrochloride","Cl.NC(CCCNC(N)=N)C(O)=O",-3.449,1,3,6]
["S3211","Thiamine HCl (Vitamin B1)","d10","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","040079,080509,080553,080556,080571,080575,080667,080712,080718,080770,083534,083775,087968,091623,206106,","Others","Vitamin","Metabolism","Thiamine or vitamin B1 is a water-soluble vitamin of the B complex, its phosphate derivatives are involved in many cellular processes.",337.27,"67-03-8","<1",0,68,201.62,"http://selleckchem.com/products/thiamine-hcl-vitamin-b1.html","C12H17N4OS.HCl","Hydrochloride","N/A","Cl.[Cl-].CC1=NC=C(C[N+]2=CSC(=C2C)CCO)C(=N1)N",-1.244,2,2,4]
["S3642","Cesium chloride","e10","L1300-37","in 10mM Water","NDC","USP42-NF37",null,"Others","Others","Others","Cesium chloride (CsCl) is the inorganic compound. It is widely used medicine structure in isopycnic centrifugation for separating various types of DNA and is a reagent in analytical chemistry.",168.36,"7647-17-8","<1",0,33,196.01,"http://selleckchem.com/products/cesium-chloride.html","CsCl","inorganic salt","CsCl","Cl[Cs]",0.485,0,0,0]
["S3649","Ceftazidime","f10","L1300-37","in 10mM Water","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,JP17,BP2015,IP2010","062640,065196,065481,065482","Infection","Anti-infection,Selection Antibiotics for Transfected Cell","Microbiology","Ceftazidime(GR20263) is a third-generation cephalosporin that has activity against Gram-negative bacilli, including Pseudomonas aeruginosa.",546.58,"72558-82-8",4,7.32,100,182.96,"http://selleckchem.com/products/ceftazidime.html","C22H22N6O7S2","inner salt","GR20263","CC(C)(O\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)C[N+]3=CC=CC=C3)C4=CSC(=N4)N)C(O)=O",-0.693,6,2,9]
["S3650","Penicillin V potassium salt","g10","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC","USP42-NF37,IP2010","060518,061528,061529,061530,061571,061624,061758,062935,062936,062981,064071,065435,090549","Infection","Antibiotics,Bacterial","Microbiology","Phenoxymethylpenicillin, also known as penicillin V, is an antibiotic useful for the treatment of a number of bacterial infections. It acts by inhibiting the biosynthesis of cell-wall peptidoglycan.",388.48,"132-98-9","<1",0,77,198.21,"http://selleckchem.com/products/penicillin-v-potassium-salt.html","C16H17N2O5S.K","potassium salt","Phenoxymethylpenicillin potassium salt","[K+].CC1(C)SC2C(NC(=O)COC3=CC=CC=C3)C(=O)N2C1C([O-])=O",-0.55,3,1,5]
["S3662","Pirenzepine dihydrochloride","h10","L1300-37","in 10mM Water","DMF","EP9.1,BP2015",null,"Gastrointestinal Disease","AChR","Neuronal Signaling","Pirenzepine is an antimuscarinic agent which inhibits gastric acid secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular and urinary functions.",424.32,"29868-97-1",1,2.36,84,197.96,"http://selleckchem.com/products/pirenzepine-dihydrochloride.html","C19H21N5O2.2HCl","dihydrochloride","N/A","Cl.Cl.CN1CCN(CC1)CC(=O)N2C3=C(C=CC=C3)C(=O)NC4=CC=CN=C24",1.803,3,1,2]
["S3667","Imipenem","a11","L1300-37","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP7.5,JP17,印度药典","090577,090825,091007,050587,050630,062756","Infection","β-lactamase","Microbiology","Imipenem acts as an inhibitor of AmpC β-lactamase and is an antibiotic useful for the treatment of a number of bacterial infections.",317.36,"74431-23-5",1,3.15,63,198.51,"http://selleckchem.com/products/imipenem.html","C12H17N3O4S.H2O","hydrate","N/A","O.CC(O)C1C2CC(=C(N2C1=O)C(O)=O)SCCNC=N",-1.825,2,2,7]
["S3737","Cangrelor Tetrasodium","b11","L1300-37","in 10mM Water","DMF",null,null,"Cardiovascular Disease","P2 Receptor","Neuronal Signaling","Cangrelor (AR-C69931MX) is a potent, competitive P2Y12 receptor inhibitor that is administered by intravenous infusion and rapidly achieves near complete inhibition of ADP-induced platelet aggregation.",864.29,"163706-36-3",2,2.31,100,115.7,"http://selleckchem.com/products/cangrelor-tetrasodium.html","21Cl2F3N5O12P3S2.4Na","tetrasodium salt","AR-C69931MX","CSCCNC1=NC(=NC2=C1N=C[N]2C3OC(CO[P](=O)(O[Na])O[P](=O)(O[Na])C(Cl)(Cl)[P](=O)(O[Na])O[Na])C(O)C3O)SCCC(F)(F)F",2.787,10,3,20]
["S3748","Acamprosate Calcium","c11","L1300-37","in 10mM Water","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","200142,200143,202229,205995","Psychotic disorders","GABA Receptor","Transmembrane Transporters","Acamprosate (N-Acetylhomotaurine, Calcium acetylhomotaurinate,N-acetylhomotaurinate) is a synthetic compound with a chemical structure similar to the amino acid neurotransmitter gamma-aminobutyric acid (GABA) and the amino acid neuromodulator taurine.",200.24,"77337-73-6","<1",0,40,199.76,"http://selleckchem.com/products/acamprosate-calcium.html","C5H11NO4S.1/2Ca","calcium salt","N-Acetylhomotaurine Calcium, calcium acetylhomotaurinate,N-acetylhomotaurinate","CC(=O)NCCC[S]([O-])(=O)=O",-2.67,1,1,4]
["S3752","isoleucine","d11","L1300-37","in 10mM Water","DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017",null,"Neurological Disease","Others","Others","Isoleucine (Ile) is a non-polar, uncharged (at physiological pH), aliphatic amino acid that is used in the biosynthesis of proteins.",131.17,"73-32-5","<1",0,26,198.22,"http://selleckchem.com/products/isoleucine.html","C6H13NO2","free base","Ile","CCC(C)C(N)C(O)=O",0,0,0,0]
["S3753","L-Leucine","e11","L1300-37","in 10mM Water","NDC,DMF","KP Ⅹ,JP17,BP2015",null,"Metabolic Disease","mTOR","PI3K/Akt/mTOR","Leucine ((S)-Leucine, Leu) is one of nine essential amino acids in humans which is important for protein synthesis and many metabolic functions. It contributes to regulation of blood-sugar levels; growth and repair of muscle and bone tissue; growth hormone production; and wound healing.  L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway.",131.17,"61-90-5","<1",0,5,38.12,"http://selleckchem.com/products/l-leucine.html","C6H13NO2","free base","(S)-Leucine, Leu","CC(C)CC(N)C(O)=O",0,0,0,0]
["S3798","L-Citrulline","f11","L1300-37","in 10mM Water","NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37",null,"Nutritional support","Others","Others","L-citrulline is a substance called a non-essential amino acid that is used as a sports performance and cardiovascular health supplement.",175.19,"372-75-8","<1",0,35,199.78,"http://selleckchem.com/products/l-citrulline.html","C6H13N3O3","free base","N/A","NC(CCCNC(N)=O)C(O)=O",0,0,0,0]
["S3852","L-Theanine","g11","L1300-37","in 10mM Water","NDC",null,null,"Cardiovascular Disease/Neurological Disease","Others","Others","L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation.",174.2,"3081-61-6","<1",0,34,195.18,"http://selleckchem.com/products/l-theanine.html","C7H14N2O3","free base","N/A","CCNC(=O)CCC(N)C(O)=O",0,0,0,0]
["S3861","Sodium Demethylcantharidate","h11","L1300-37","in 10mM Water","CFDA",null,null,"Cancer/Infection","PP2A","PI3K/Akt/mTOR","Demethylcantharidin (norcantharidin) is a synthetic analogue of cantharidin and has potent antitumor activity.",208.14,"13114-29-9","<1",0,41,196.98,"http://selleckchem.com/products/sodium-demethylcantharidate.html","C8H9O5.Na","free base","Sodium norcantharidin","OC(=O)C1C2CCC(O2)C1C(=O)O[Na]",0,0,0,0]
["S3953","L-Lysine hydrochloride","a2","L1300-38","in 10mM Water","DMF,CFDA","JP17",null,"Infection","Others","Others","L-Lysine hydrochloride is an essential amino acid. It is often added to animal feed used as a dietary supplement and plays a major role in calcium absorption, building muscle protein, recovering from surgery or sports injuries, and the body's production of hormones, enzymes, and antibodies.",182.65,"657-27-2","<1",0,100,547.5,"http://selleckchem.com/products/l-lysine-hydrochloride.html","C6H14N2O2.HCl","hydrochloride","N/A","Cl.NCCCCC(N)C(O)=O",0,0,0,0]
["S3963","DL-Glutamine","b2","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,JP17","208587,021667","Nutritional support","Others","Others","DL-Glutamine (Glutamin, 2-amino-4-carbamoylbutanoic acid) is a non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes.",146.14,"6899-04-3","<1",0,29,198.44,"http://selleckchem.com/products/dl-glutamine.html","C5H10N2O3","free base","Glutamin, 2-amino-4-carbamoylbutanoic acid","NC(CCC(N)=O)C(O)=O",0,0,0,0]
["S3973","L-SelenoMethionine","c2","L1300-38","in 10mM Water","FDA,DMF","USP42-NF37","017098,017257,017322,017047","Cancer/Immunology","ROS","Immunology & Inflammation","L-SelenoMethionine (SeMet), a naturally occurring amino acid, is a major food-form of selenium. It has been used as a supplement, and exhibits some important functions like cancer prevention and antioxidative defense.",196.11,"3211-76-5","<1",0,39,198.87,"http://selleckchem.com/products/l-selenomethionine.html","C5H11NO2Se","free base","N/A","C[Se]CCC(N)C(O)=O",0,0,0,0]
["S4008","Pemirolast potassium","d2","L1300-38","in 10mM Water","FDA,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17","021079","Immunology/Inflammation/Ophthalmology","Histamine Receptor","Neuronal Signaling","Pemirolast potassium (BMY26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.",266.3,"100299-08-9","<1",0,53,199.02,"http://selleckchem.com/products/pemirolast-bmy-26517-potassium.html","C10H7N6O.K","Potassium","BMY26517","[K+].CC1=CC=CN2C(=O)C(=CN=C12)C3=NN=N[N-]3",-1.246,5,0,1]
["S4013","Sodium Monofluorophosphate","e2","L1300-38","in 10mM Water","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,USP39-NF34","019518","Others","phosphatase","Metabolism","Sodium Monofluorophosphate (NSC248) is a competitive inhibitor of pyruvate kinase and alkaline phosphatase with Ki of 3.4 mM and 69 μM, respectively, which also irreversibly inhibits phosphorylase phosphatase with Ki of 0.5 mM.",143.95,"10163-15-2","<1",0,29,201.46,"http://selleckchem.com/products/sodium-monofluorophosphate.html","FNa2O3P","Disodium salt","NSC248","[Na+].[Na+].[O-][P]([O-])(F)=O",-2.357,0,0,0]
["S4027","Flavoxate HCl","f2","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,BP2017,JP16","076234,076831,076835","Neurological Disease","AChR","Neuronal Signaling","Flavoxate (NSC-114649) is a muscarinic AChR antagonist with IC50 of 12.2 μM.",427.92,"3717-88-2",3,7.01,10,23.37,"http://selleckchem.com/products/flavoxate-hcl.html","C24H25NO4.HCl","hydrochloride","NSC-114649","Cl.CC1=C(OC2=C(C=CC=C2C(=O)OCCN3CCCCC3)C1=O)C4=CC=CC=C4",4.876,4,0,6]
["S4028","Dexamethasone Sodium Phosphate","g2","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,Ph.Int_6th,BP2017,IP2010","040069,040572,040802,040803,081125,081126,083161,083702,084170,084173,084282,084355,084493,084752,084855,084916,085606,085641,087065,087440,087668,087702,088522,088771,089169,089280,089281,089282,089372,203129,206781,207521,208689,209192,211036","Hematology/Immunology/Inflammation/Infection","Autophagy,Complement System,COVID-19,COX,IL Receptor","Immunology & Inflammation","Dexamethasone (Dexamethasone 21-phosphate disodium salt) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator  that has anti-inflammatory and immunosuppressant effects.",516.4,"55203-24-2","<1",0,103,199.46,"http://selleckchem.com/products/dexamethasone-sodium-phosphate.html","C22H30FO8P.2Na","Disodium salt","Dexamethasone 21-phosphate disodium salt","[Na+].[Na+].CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO[P]([O-])([O-])=O",-0.541,3,1,4]
["S4029","Colistin Sulfate","h2","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,JP17,BP2017","050355,050356","Infection","Bacterial","Microbiology","Colistin (Polymixin E) is a cyclic cationic decapeptide linked to a fatty acid side chain, it belongs to a group of similarly structured bacterial antimicrobial peptides.",1400.63,"1264-72-8","<1",0,100,10,"http://selleckchem.com/products/colistin-sulfate.html","C52H98N16O13.5/2H2SO4","Sulfate","Polymixin E Sulfate","CCC(C)CCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCN)NC1=O)C(C)O.CCC(C)CCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC2CCNC(=O)C(NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCN)NC2=O)C(C)O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O",0,0,0,0]
["S4030","Gentamicin Sulfate","a3","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,Ph.Int_5th","062196,062251,062264,062307,062318,062340,062351,062354,062356,062366,062413,062420,062427,062471,062477,062496,062507,062523,062530,062531,062533,062534,062612,062635,062932,063106,063149,064048,064054,064056,064093,065024,065121,209233","Infection","Antibiotics,Antibiotics for Mammalian Cell Culture,Antibiotics for Plant Cell Culture,Selection Antibiotics for Transfected Cell","Microbiology","Gentamycin Sulfate (NSC-82261, SCH9724) is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms.",0,"1405-41-0","<1",0,100,10,"http://selleckchem.com/products/gentamicin-sulfate.html","H2SO4.xUnspecified","Sulfate","NSC-82261, SCH9724","CCN.CNC(C)C.CNC1C(O)C(OCC1(C)O)OC2C(N)CC(N)C(OC3OC(CCC3N)[R])C2O.CC(C)N.O[S](O)(=O)=O",0,0,0,0]
["S4052","Netilmicin Sulfate","b3","L1300-38","in 10mM Water","FDA,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,KP Ⅹ,BP2017,JP15","050544","Infection","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics","Microbiology","Netilmicin Sulfate is a member of the aminoglycoside family of antibiotics.",1441.55,"56391-57-2","<1",0,288,199.78,"http://selleckchem.com/products/netilmicin-sulfate.html","C21H41N5O7.2.5H2SO4","Sulfate","N/A","CCNC1CC(N)C(OC2OC(=CCC2N)CN)C(O)C1OC3OCC(C)(O)C(NC)C3O.CCNC4CC(N)C(OC5OC(=CCC5N)CN)C(O)C4OC6OCC(C)(O)C(NC)C6O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O",-10.844,8,14,16]
["S4093","Bismuth Subcitrate Potassium","c3","L1300-38","in 10mM Water","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","050786","Infection","Antibiotics,Bacterial","Microbiology","Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.",782.67,"880149-29-1","<1",0,100,127.77,"http://selleckchem.com/products/bismuth-subcitrate-potassium.html","C12H8BiK5O14","Potassium salt","N/A","[K+].[K+].[K+].[K+].[K+].[BiH6+3].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O",-11.482,0,0,10]
["S4094","Tetramisole HCl","d3","L1300-38","in 10mM Water","DMF","Martindale:The Extra Pharmacopoeia",null,"Infection","Parasite","Microbiology","Tetramisole(R-829,(±)-Tetramisole hydrochloride) is a mixture of dextro- and levo isomers used as an anthelmintic.",240.75,"5086-74-8","<1",0,41,170.3,"http://selleckchem.com/products/tetramisole-hcl.html","C11H12N2S.HCl","Hydrochloride","R-829,(±)-Tetramisole hydrochloride","Cl.C1CN2CC(N=C2S1)C3=CC=CC=C3",2.672,1,0,1]
["S4108","Clodronate Disodium","e3","L1300-38","in 10mM Water","DMF,CFDA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2015",null,"Cancer/Metabolic Disease","Others","Metabolism","Clodronate Disodium, a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.",288.86,"22560-50-5","<1",0,72,249.26,"http://selleckchem.com/products/clodronate-disodium.html","CH4Cl2O6P0.2Na","Disodium salt","N/A","[Na+].[Na+].O[P]([O-])(=O)C(Cl)(Cl)[P](O)([O-])=O",-1.706,0,0,2]
["S4117","Histamine Phosphate","f3","L1300-38","in 10mM Water","FDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP7.5,BP2017,IP2010","000734","Gastroenterology","Histamine Receptor","Neuronal Signaling","Histamine(Histamine diphosphate) acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors.",307.14,"51-74-1","<1",0,42,136.75,"http://selleckchem.com/products/histamine-phosphate.html","C5H9N.2H3O4P","Phosphate","Histamine diphosphate","NCCC1=C[NH]C=N1.O[P](O)(O)=O.O[P](O)(O)=O",-1.651,1,2,2]
["S4121","Succinylcholine Chloride Dihydrate","g3","L1300-38","in 10mM Water","FDA,DMF,NDC","USP42-NF37,IP2010","080997,085400,209467,210231,211432","Neurological Disease","AChR","Neuronal Signaling","Succinylcholine Chloride Dihydrate (Suxamethonium) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.",397.34,"6101-15-1",1,2.52,79,198.82,"http://selleckchem.com/products/succinylcholine-suxamethonium-chloride-dihydrate.html","C14H30N2O4.2Cl.2H2O","Chloride","Suxamethonium Chloride Dihydrate","O.O.[Cl-].[Cl-].C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C",-8.102,4,0,11]
["S4127","Terbutaline Sulfate","h3","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","075877,076770,076853,076887,077152,078151,078630,200122","Immunology","Adrenergic Receptor","GPCR & G Protein","Terbutaline Sulfate(Terbutaline hemisulfate) is a selective β2-adrenergic receptor agonist with IC50 of 53 nM.",548.65,"23031-32-5","<1",0,100,182.27,"http://selleckchem.com/products/terbutaline-sulfate.html","C24H38N2O6.H2SO4","Sulfate","Terbutaline hemisulfate","CC(C)(C)NCC(O)C1=CC(=CC(=C1)O)O.CC(C)(C)NCC(O)C2=CC(=CC(=C2)O)O.O[S](O)(=O)=O",2.001,0,8,8]
["S4130","Mildronate","a4","L1300-38","in 10mM Water",null,"EP9.2",null,"Cardiovascular Disease","Hydroxylase","Metabolism","Mildronate (Meldonium, MET-88, Quaterin) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.",147.19,"76144-81-5","<1",0,29,197.02,"http://selleckchem.com/products/mildronate.html","C6H14N2O2","free base","Meldonium, MET-88, Quaterin","C[N+](C)(C)NCCC(O)=O",-1.797,1,1,4]
["S4137","Eprazinone 2HCl","b4","L1300-38","in 10mM Water","CFDA,PMDA","Martindale:The Extra Pharmacopoeia",null,"Respiratory Disease","Others","Others","Eprazinone (NSC 317935) is a mucolytic.",453.44,"10402-53-6",1,2.21,18,39.7,"http://selleckchem.com/products/eprazinone-2hcl.html","C24H32N2O2.2HCl","HCl","NSC 317935","Cl.Cl.CCOC(CN1CCN(CC1)CC(C)C(=O)C2=CC=CC=C2)C3=CC=CC=C3",4.838,2,0,9]
["S4144","Amprolium HCl","c4","L1300-38","in 10mM Water","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017,IP2010",null,"Parasite","Vitamin","Metabolism","Amprolium chloride is a thiamin antagonist, which prevents carbohydrate synthesis by blocking thiamine uptake.",315.24,"137-88-2",2,6.34,63,199.85,"http://selleckchem.com/products/amprolium-hcl.html","C14H19N4.HCl.Cl","Hydrochloride","N/A","Cl.[Cl-].CCCC1=NC=C(C[N+]2=C(C)C=CC=C2)C(=N1)N",-0.036,2,1,4]
["S4146","Bacitracin","d4","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,Ph.Int_5th,USP39-NF34,BP2015,JP16,IP2010","060282,060687,060733,061212,061699,062158,062453,062456,062696,062799,062857,065116,090211,203177,206719","Infection","Bacterial,Selection Antibiotics for Transfected Cell","Microbiology","Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synthesis.",1408.67,"1405-87-4",0,0,100,70.99,"http://selleckchem.com/products/bacitracin.html","C65H101N17O16S","free base","N/A","CCC(C)C(NC(=O)C(CCC(O)=O)NC(=O)C(CC(C)C)NC(=O)C1CN=C(S1)C(N)C(C)C)C(=O)NC2CCCCNC(=O)C(CC(N)=O)NC(=O)C(CC(O)=O)NC(=O)C(CC3=C[NH]C=N3)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(NC(=O)C(CCCN)NC2=O)C(C)CC",-6.458,16,15,30]
["S4157","Chloroquine diphosphate","e4","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,Ph.Int_6th,BP2017,IP2010","040516,080880,080886,083082,087228,087504,087979,088030,090249,090610,090612,091621","Infection/Parasitology","Anti-infection,ATM/ATR,Autophagy,COVID-19,TLR","PI3K/Akt/mTOR","Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. Chloroquine is also an inhibitor of toll-like receptors (TLRs).",515.86,"50-63-5","<1",0,100,193.85,"http://selleckchem.com/products/chloroquine-phosphate.html","C18H26ClN3.2H3O4P","diphosphate","N/A","CCN(CC)CCCC(C)NC1=CC=NC2=C1C=CC(=C2)Cl.O[P](O)(O)=O.O[P](O)(O)=O",3.408,1,1,8]
["S4158","Ceftriaxone disodium salt hemi (heptahydrate)","f4","L1300-38","in 10mM Water","marketed in Eastern Europe","Martindale:The Extra Pharmacopoeia,CP2005,KP Ⅹ,EP9.1,JP17,BP2017",null,"Infection","Antibiotics","Microbiology","Ceftriaxone disodium salt hemi (heptahydrate) is a third-generation cephalosporin antibiotic.",661.6,"104376-79-6",1,1.51,100,151.15,"http://selleckchem.com/products/ceftriaxone-sodium-trihydrate.html","C18H16N8O7S3.7/2H2O.2Na","disodium salt hemi","N/A","O.[Na;v0].CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)CSC3=NC(=O)C(=O)NN3C)C4=CSC(=N4)N",-1.716,8,2,8]
["S4174","Sodium Gluconate","g4","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP39-NF34","019843,018252,019711,019006,019696,018274,017609,017586,019024,017637,018406,018406,017451,017378,017378,019326","Nutritional support","Others","Others","Sodium gluconate is the sodium salt of gluconic acid widely used in food and pharmaceutical industry.",218.14,"527-07-1","<1",0,44,201.71,"http://selleckchem.com/products/sodium-gluconate.html","C6H11O7.Na","Sodium salt","527-07-1","[Na+].OCC(O)C(O)C(O)C(O)C([O-])=O",-4.287,0,5,5]
["S4180","Nefopam HCl","h4","L1300-38","in 10mM Water","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease","Sodium Channel","Transmembrane Transporters","Nefopam HCl(Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline reuptake.",289.8,"23327-57-3",1,3.45,21,72.46,"http://selleckchem.com/products/nefopam-hcl.html","C17H19NO.HCl","Hydrochloride","Fenazoxine hydrochloride","Cl.CN1CCOC(C2=CC=CC=C2)C3=C(C1)C=CC=C3",3.52,1,0,1]
["S4183","Paromomycin Sulfate","a5","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,Ph.Int_6th","064171,065173","Infection","Antibiotics,Antibiotics for Mammalian Cell Culture,Antibiotics for Plant Cell Culture,Selection Antibiotics for Transfected Cell","Microbiology","Paromomycin Sulfate(Aminosidine sulfate) is an aminoglycoside antibiotics inhibiting protein synthesis in non-resistant cells by binding to 16S ribosomal RNA.",713.71,"1263-89-4","<1",0,100,140.11,"http://selleckchem.com/products/paromomycin-sulfate.html","C23H45N5O14.xH2SO4","Sulfate","Aminosidine sulfate","NCC1OC(OC2C(O)C(OC2CO)OC3C(O)C(N)CC(N)C3OC4OC(CO)C(O)C(O)C4N)C(N)C(O)C1O.O[S](O)(=O)=O",-9.277,6,13,9]
["S4215","Ribostamycin Sulfate","b5","L1300-38","in 10mM Water","CFDA","KP Ⅹ ,JP17",null,"Infection","Antibiotics,Selection Antibiotics for Transfected Cell","Microbiology","Ribostamycin Sulfate(Vistamycin Sulfate,Landamycine) is an aminoglycoside antibiotic, containing a neutral sugar moiety, and is produced by Streptomyces ribosidiﬁcus.",552.55,"53797-35-6","<1",0,100,180.98,"http://selleckchem.com/products/ribostamycin-sulfate.html","C17H34N4O10.H2SO4","Sulfate","Vistamycin Sulfate,Landamycine","NCC1OC(OC2C(N)CC(N)C(O)C2OC3OC(CO)C(O)C3O)C(N)C(O)C1O.O[S](O)(=O)=O",-7.24,4,10,6]
["S4234","Capreomycin Sulfate","c5","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,Ph.Int_5th","202634,204796","Infection","Antibiotics","Microbiology","Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit.",750.78,"1405-37-4","<1",0,100,133.19,"http://selleckchem.com/products/capreomycin-sulfate.html","C25H44N14O7.H2SO4","Sulfate","N/A","CC1NC(=O)C(N)CNC(=O)C(NC(=O)C(NC(=O)C(CNC(=O)CC(N)CCCN)NC1=O)=CNC(N)=O)C2CCNC(=N2)N.O[S](O)(=O)=O",-7.669,8,13,9]
["S4236","Proflavine Hemisulfate","d5","L1300-38","in 10mM Water","NDC","Martindale:The Extra Pharmacopoeia",null,"Infection","Anti-infection,DNA/RNA Synthesis","Microbiology","Proflavine Hemisulfate is a topical antiseptic by interchelating DNA, thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands.",258.25,"1811-28-5","<1",0,22,85.19,"http://selleckchem.com/products/proflavine-hemisulfate.html","C13H11N3.1/2H2SO4","Sulfate","N/A","NC1=CC=C2C=C3C=CC(=CC3=NC2=C1)N.NC4=CC=C5C=C6C=CC(=CC6=NC5=C4)N.O[S](O)(=O)=O",3.113,2,4,0]
["S4245","Sodium ascorbate","e5","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,EP9.8","021881,090145,209381","Nutritional support","Vitamin","Metabolism","Sodium Ascorbate (Sodium Vitamin C) is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.",198.11,"134-03-2",2,9.94,40,198.88,"http://selleckchem.com/products/sodium-ascorbate.html","C6H7NaO6","Sodium Salt","Sodium Vitamin C","[NaH].OCC(O)C1OC(=O)C(O)C1O",-2.229,2,4,2]
["S4254","Apramycin Sulfate","f5","L1300-38","in 10mM Water",null,"BP2019;Martindale:The Extra Pharmacopoeia",null,"Infection","Antibiotics","Microbiology","Apramycin Sulfate (Ai3-29795) is an aminoglycoside antibiotic, which binds to the deep groove of the RNA.",637.66,"65710-07-8","<1",0,100,156.82,"http://selleckchem.com/products/apramycin-sulfate.html","C21H41N5O11.xH2SO4","Sulfate","Ai3-29795","CNC1C(O)C2OC(OC3C(N)CC(N)C(O)C3O)C(N)CC2OC1OC4OC(CO)C(N)C(O)C4O.O[S](O)(=O)=O",-7.63,5,11,6]
["S4271","Isepamicin Sulphate","g5","L1300-38","in 10mM Water","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Infection","Antibiotics,Bacterial","Microbiology","Isepamicin Sulphate (Isepamicine, Isepamycin, sch21420) is an aminoglycoside antibiotic, which inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit.",667.68,"67814-76-0","<1",0,100,149.77,"http://selleckchem.com/products/isepamicin-sulphate.html","C22H45N5O16S","free base","Isepamicine (Isepamycin, sch21420) Sulphate","CNC1C(O)C(OCC1(C)O)OC2C(O)C(OC3OC(CN)C(O)C(O)C3O)C(N)CC2NC(=O)C(O)CN.O[S](O)(=O)=O",-7.948,5,11,9]
["S4287","Micafungin (FK 463) Sodium","h5","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","207344","Infection","Fungal","Microbiology","Micafungin Sodium (FK463, Mycamine) is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug.",1292.26,"208538-73-2",0,0,100,77.38,"http://selleckchem.com/products/micafungin-sodium.html","C56H70N9NaO23S","Sodium Salt","Mycamine Sodium","CCCCCOC1=CC=C(C=C1)C2=CC(=NO2)C3=CC=C(C=C3)C(=O)NC4CC(O)C(O)NC(=O)C5C(O)C(C)CN5C(=O)C(NC(=O)C(NC(=O)C6CC(O)CN6C(=O)C(NC4=O)C(C)O)C(O)C(O)C7=CC(=C(O)C=C7)O[S](=O)(=O)O[Na])C(O)CC(N)=O",-2.974,13,15,19]
["S4298","Amifostine trihydrate","a6","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","077126,204363","Cancer","Others","Others","Amifostine trihydrate(WR2721 trihydrate) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.",268.27,"112901-68-5","<1",0,42,156.56,"http://selleckchem.com/products/amifostine.html","C5H15N2O3PS.3H2O","trihydrate","WR2721 trihydrate","O.O.O.NCCCNCCS[P](O)(O)=O",-1.471,0,2,7]
["S4311","Calcium Gluceptate","b6","L1300-38","in 10mM Water","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","006470,080001,083159,089373","Metabolic Disease","Others","Others","Calcium gluceptate is a calcium salt used in the treatment and prophylaxis of hypocalcemia and as an electrolyte replenisher.",490.42,"17140-60-2",1,2.04,98,199.83,"http://www.selleckchem.com/products/calcium-gluceptate.html","C14H26CaO16","Gluceptate","N/A","OCC(O)C(O)C(O)C(O)C(O)C(=O)O[Ca]OC(=O)C(O)C(O)C(O)C(O)C(O)CO",-6.465,4,12,16]
["S4314","Ceftazidime Pentahydrate","c6","L1300-38","in 10mM Water","DMF,HMA","Martindale:The Extra Pharmacopoeia,EP9.3,BP2017",null,"Infection","Others","Others","Ceftazidime is a β-lactam antibacterial agent which has demonstrated a broad spectrum of activity against Gram-positive and Gram-negative aerobic bacteria.",636.65,"78439-06-2",4,6.28,100,157.07,"http://www.selleckchem.com/products/ceftazidime-pentahydrate.html","C22H32N6O12S2","Pentahydrate","O.O.O.O.O.[H][C@]12SCC(C[N+]3=CC=CC=C3)=C(N1C(=O)[C@H]2NC(=O)C(=N\\OC(C)(C)C(O)=O)\\C1=CSC(N)=N1)C([O-])=O |r, c:8, 10, 12, 36, t:6, 32|","O.O.O.O.O.CC(C)(O/N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)C[N+]3=CC=CC=C3)C4=CSC(=N4)N)C(O)=O",6,2,9,0]
["S4328","Guanethidine Sulfate","d6","L1300-38","in 10mM Water","DMF","JP16",null,"Cardiovascular Disease","Others","Others","Guanethidine is an antihypertensive drug that reduces the release of catecholamines, such as norepinephrine.",494.7,"60-02-6",0,0,10,20.21,"http://selleckchem.com/products/guanethidine-sulfate.html","C20H44N8.H2O4S","Sulfate","N/A","NC(=N)NCCN1CCCCCCC1.NC(=N)NCCN2CCCCCCC2.O[S](O)(=O)=O",0,0,0,0]
["S4360","Tolmetin Sodium","e6","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP39-NF34","073290,073308,073310,073311,073392,073393,073462,073519,073527,073588,074002,074399,074473,074729","Immunology/Inflammation","COX","Immunology & Inflammation","Tolmetin(MCN2559) is a non-steroidal anti-inflammatory drug of the arylalkanoic acids. Tolmetin sodium dihydrate is a non-steroidal antiinflammatory agent, and acts as a non-selective COX inhibitor.",315.3,"64490-92-2","<1",0,63,199.81,"http://www.selleckchem.com/products/tolmetin-sodium.html","C15H14NO3.Na.2H2O","sodium","MCN2559","O.O.C[N]1C(=CC=C1C(=O)C2=CC=C(C)C=C2)CC(=O)O[Na]",2.943,3,0,5]
["S4392","Potassium Canrenoate","f6","L1300-38","in 10mM Water","PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Cardiovascular Disease/Metabolic Disease","Others","Others",0,396.56,"2181-04-6",0,0,40,100.87,"http://selleckchem.com/products/potassium-canrenoate.html","C22H29KO4",0,"Canrenoic Acid Potassium Salt","[K+].CC12CCC(=O)C=C1C=CC3C2CCC4(C)C3CCC4(O)CCC([O-])=O",0,0,0,0]
["S4430","Hydroxychloroquine Sulfate (NSC 4375)","g6","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.3,KP Ⅹ,BP2017","040081,040104,040133,040150,040274,040657,040760,040766,201691,210441,210543,210577,210959","Infection/Parasitology","Anti-infection,Autophagy,COVID-19,TLR","Autophagy","Hydroxychloroquine Sulfate (NSC 4375, HCQ) is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.",433.95,"747-36-4","<1",0,67,154.4,"http://selleckchem.com/products/hydroxychloroquine-sulfate.html","C18H28ClN3O5S","Sulfate","HCQ","CCN(CCO)CCCC(C)NC1=CC=NC2=CC(=CC=C12)Cl.O[S](O)(=O)=O",2.85,1,2,9]
["S4523","Dihydrostreptomycin sulfate","h6","L1300-38","in 10mM Water","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017",null,"Infection","Antibiotics,Antibiotics for Mammalian Cell Culture,Bacterial,Selection Antibiotics for Transfected Cell","Microbiology","Dihydrostreptomycin sulfate is an aminoglycoside antibiotic, used to treat bacterial diseases in cattle, pigs and sheep. Dihydrostreptomycin is a derivative of streptomycin.",1461.42,"5490-27-7","<1",0,100,68.43,"http://selleckchem.com/products/dihydrostreptomycin-sulfate.html","2C21H41N7O12.3H2SO4","Sulfate","N/A","CNC1C(O)C(O)C(CO)OC1OC2C(OC(C)C2(O)CO)OC3C(O)C(O)C(NC(N)=N)C(O)C3NC(N)=N.CNC4C(O)C(O)C(CO)OC4OC5C(OC(C)C5(O)CO)OC6C(O)C(O)C(NC(N)=N)C(O)C6NC(N)=N.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O",-14.916,8,24,22]
["S4540","Sisomicin sulfate","a7","L1300-38","in 10mM Water","CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,JP15",null,"Infection","Antibiotics","Microbiology","Sisomicin sulfate is an aminoglycoside antibiotic, isolated from the fermentation broth of a new species of the genus Micromonospora.",1385.45,"53179-09-2","<1",0,100,72.18,"http://selleckchem.com/products/sisomicin-sulfate.html","2C19H37N5O7.5H2SO4","Sulfate","N/A","CNC1C(O)C(OCC1(C)O)OC2C(N)CC(N)C(OC3OC(=CCC3N)CN)C2O.CNC4C(O)C(OCC4(C)O)OC5C(N)CC(N)C(OC6OC(=CCC6N)CN)C5O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O",-12.405,8,14,12]
["S4567","Eprodisate disodium","b7","L1300-38","in 10mM Water",null,"Martindale:The Extra Pharmacopoeia",null,"Others","Others","Neuronal Signaling","Eprodisate Disodium (NC-503) is the orally available disodium salt form of Eprodisate, a small-molecule, orally bioavailable, inhibitor of AA-amyloid fibrillogenesis.",248.19,"36589-58-9","<1",0,49,197.43,"http://selleckchem.com/products/eprodisate-disodium.html","C3H8O6S2.2Na","sodium","NC-503","[Na+].[Na+].[O-][S](=O)(=O)CCC[S]([O-])(=O)=O",-5.437,0,0,4]
["S4575","Pralidoxime chloride","c7","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,IP2010","018799,018986,072224","Neurological Disease","AChR","Neuronal Signaling","Pralidoxime chloride (2-PAM) is an antidote to organophosphate pesticides and chemicals; An acetylcholinesterase (AChE) reactivator.",172.61,"51-15-0","<1",0,34,196.98,"http://selleckchem.com/products/pralidoxime-chloride.html","C7H9N2O.Cl","chloride","2-PAM (chloride)","[Cl-].C[N+]1=C(C=CC=C1)\\C=N\\O",-1.122,1,0,1]
["S4582","Eflornithine (MDL-71782) hydrochloride hydrate","d7","L1300-38","in 10mM Water","FDA,DMF,EMA,NDC","Martindale:The Extra Pharmacopoeia","019879,021145","Infection","Decarboxylase","Metabolism","Eflornithine (Difluoromethylornithine, DFMO, MDL-71782, RMI-71782, α-difluoromethylornithine) hydrochloride hydrate inhibits polyamine biosynthesis by the selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis. Its biological half-life is 8 hours.",236.64,"96020-91-6","<1",0,47,198.61,"http://selleckchem.com/products/eflornithine-hydrochloride-hydrate.html","C6H12F2N2O2.HCl.H2O","hydrochloride hydrate","Difluoromethylornithine hydrochloride hydrate, DFMO hydrochloride hydrate, RMI-71782 hydrochloride hydrate, α-difluoromethylornithine hydrochloride hydrate","O.Cl.NCCCC(N)(C(F)F)C(O)=O",-3.046,1,2,5]
["S4592","Captisol (SBE-β-CD)","e7","L1300-38","in 10mM Water","DMF",null,null,"Others","Anti-infection,Hydrotropic Agents","Microbiology","Captisol (SBE-β-CD, Sulfobutylether-β-Cyclodextrin) is a novel, chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of drugs.",0,"182410-00-0","<1",0,100,10,"http://selleckchem.com/products/sbe-b-cd.html","C42H70-nO35.nNa.n(C4H8O3S)","Free Base","Sulfobutylether-β-Cyclodextrin","[Na+].[Na+].OCC1OC2OC3C(O)C(O)C(OC3CO)OC4C(O)C(O)C(OC4CO)OC5C(O)C(OCCCC[S]([O-])(=O)=O)C(OC5COCCCC[S]([O-])(=O)=O)OC6=C(CO)OC(OC7C(O)C(O)C(OC7CO)OC8C(O)C(O)C(OC8CO)OC1C(O)C2O)C(O)C6O",-15.025,16,19,19]
["S4606","Glutathione","f7","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017","018469,020079","Nutritional support","Glutathione","Metabolism","Glutathione (Isethion, Tathion, L-Glutathione reduced, GSH; γ-L-Glutamyl-L-cysteinyl-glycine) acts as an antioxidant, a free radical scavenger and a detoxifying agent. It is a tripeptide comprised of three amino acids (cysteine, glutamic acid, and glycine) present in most mammalian tissue.",307.32,"70-18-8","<1",0,61,198.49,"http://selleckchem.com/products/glutathione.html","C10H17N3O6S","free base","Isethion, Glutathion, Tathion, L-Glutathione reduced, GSH; γ-L-Glutamyl-L-cysteinyl-glycine","NC(CCC(=O)NC(CS)C(=O)NCC(O)=O)C(O)=O",-4.772,4,3,9]
["S4653","L-Ornithine hydrochloride","g7","L1300-38","in 10mM Water","DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia",null,"Nutritional support","Others","Others","L-ornithine hydrochloride ((S)-2,5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle.",168.62,"3184-13-2","<1",0,26,196.73,"https://www.selleckchem.com/products/l-ornithine-hydrochloride.html","C5H13ClN2O2","free base","(S)-2,5-Diaminopentanoic acid","Cl.NCCCC(N)C(O)=O",-3.697,1,2,4]
["S4671","Cefradine","h7","L1300-38","in 10mM Water","CFDA","Martindale:The Extra Pharmacopoeia,CP2005,KP Ⅹ,EP9.2,BP2017",null,"Infection","Antibiotics","Microbiology","Cefradine (Cephradine, Sefril, Anspor, Velosef) is a semi-synthetic cephalosporin antibiotic.",349.4,"38821-53-3","<1",0,10,28.62,"http://selleckchem.com/products/cefradine.html","C16H19N3O4S","free base","Cephradine, Sefril, Anspor, Cephradin, Velosef","CC1=C(N2C(SC1)C(NC(=O)C(N)C3=CCC=CC3)C2=O)C(O)=O",-2.277,3,2,4]
["S4700","4-Aminobutyric acid (GABA)","a8","L1300-38","in 10mM Water","CFDA, NDC, PMDA",null,null,"Neurological Disease","GABA Receptor","Neuronal Signaling","4-Aminobutyric acid (4-Aminobutanoic acid, GABA, Gamma-aminobutyric acid, Piperidic acid) is a naturally occurring neurotransmitter with central nervous system (CNS) inhibitory activity.",103.12,"56-12-2","<1",0,20,193.95,"http://selleckchem.com/products/4-aminobutyric-acid.html","C4H9NO2","free base","4-Aminobutanoic acid, GABA, Gamma-aminobutyric acid, Piperidic acid","NCCCC(O)=O",-3.076,1,1,3]
["S4703","Choline bitartrate","b8","L1300-38","in 10mM Water","CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37",null,"Nutritional support","AChR","Neuronal Signaling","Choline bitartrate (2-hydroxyethyl(trimethyl)azanium, 2,3,4-trihydroxy-4-oxobutanoate) is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acetylcholine, a chemical that facilitates communication between the nerves and muscles.",253.25,"87-67-2","<1",0,50,197.43,"http://selleckchem.com/products/choline-bitartrate.html","C5H14NO.C4H5O6","tartrate","2-hydroxyethyl(trimethyl)azanium;2,3,4-trihydroxy-4-oxobutanoate","C[N+](C)(C)CCO.OC(C(O)C([O-])=O)C(O)=O",-4.712,1,3,5]
["S4704","D-(+)-Cellobiose","c8","L1300-38","in 10mM Water",null,"Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","D-(+)-Cellobiose (Cellobiose, Cellose, Beta-Cellobiose, D-Cellobiose) is a substrate of β-glucosidase.",342.3,"528-50-7",3,8.76,68,198.66,"http://selleckchem.com/products/d-cellobiose.html","C12H22O11","free base","Cellobiose, Cellose, Beta-Cellobiose, D-Cellobiose","OCC1OC(OC2C(O)C(O)C(O)OC2CO)C(O)C(O)C1O",-4.261,3,7,4]
["S4721","L-Glutamic acid monosodium salt","d8","L1300-38","in 10mM Water","DMF,NDC,HMA",null,null,"Inflammation/Psychotic disorders","GluR","Neuronal Signaling","L-Glutamic acid monosodium salt is the sodium salt of glutamic acid, found naturally in tomatoes, cheese and other foods.   L-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). (S)-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.",169.11,"142-47-2","<1",0,33,195.14,"http://selleckchem.com/products/l-glutamic-acid-monosodium-salt.html","C5H8NO4.Na","sodium salt","Monosodium glutamate, MSG","NC(CCC(=O)O[Na])C(O)=O",-3.368,3,1,5]
["S4740","Sodium ferulate","e8","L1300-38","in 10mM Water","CFDA","CP2005",null,"Cardiovascular Disease/Hematology","5-HT Receptor","Neuronal Signaling","Sodium ferulate (SF, Ferulic acid sodium salt), the sodium salt of ferulic acid, is a drug used in traditional Chinese medicine for treatment of cardiovascular and cerebrovascular diseases and to prevent thrombosis.",216.17,"24276-84-4",2,9.25,43,198.92,"http://selleckchem.com/products/ferulic-acid-sodium.html","C10H9O4.Na","Sodium salt","Ferulic acid sodium salt","[Na+].COC1=CC(=CC=C1O)\\C=C\\C([O-])=O",0.195,1,1,3]
["S4741","Danshensu","f8","L1300-38","in 10mM Water",null,"CP2005",null,"Cardiovascular Disease","P450 (e.g. CYP17)","Metabolism","Danshensu (Salvianic acid A), a herbal preparation used in traditional Chinese medicine, possesses potential antitumor and anti‑angiogenesis effects. Danshensu inhibits CYP2E1 and CYP2C9 with IC50 of 36.63 and 75.76 μm, respectively.",198.17,"76822-21-4","<1",0,23,116.06,"http://selleckchem.com/products/danshensu.html","C9H10O5","free base","Salvianic acid A","OC(CC1=CC=C(O)C(=C1)O)C(O)=O",0.679,1,3,3]
["S4770","Creatine phosphate disodium salt","g8","L1300-38","in 10mM Water",null,"Martindale:The Extra Pharmacopoeia",null,"Nutritional support","Others","Others","Phosphocreatine, also known as creatine phosphate (CP) or PCr (Pcr), is a phosphorylated creatine molecule that serves as a rapidly mobilizable reserve of high-energy phosphates in skeletal muscle and the brain to recycle adenosine triphosphate, the energy currency of the cell.",255.08,"922-32-7","<1",0,51,199.94,"http://selleckchem.com/products/creatine-phosphate-disodium-salt.html","C4H8N3O5P.2Na","disodium salt","Phosphocreatine disodium salt","[Na+].[Na+].CN(CC(O)=O)C(=N)N[P]([O-])([O-])=O",0,0,0,0]
["S4810","Glycylglycine","h8","L1300-38","in 10mM Water","DMF",null,null,"Others","Others","Others","Glycylglycine (Diglycine, Diglycocoll, Glycine dipeptide), the simplest peptide made of two glycine molecules, is usually used in the synthesis of more complicated peptides.",132.12,"556-50-3","<1",0,26,196.79,"http://selleckchem.com/products/glycylglycine.html","C4H8N2O3","free base","Diglycine, Diglycocoll, Glycine dipeptide, N-Glycylglycine","NCC(=O)NCC(O)=O",0,0,0,0]
["S4811","VitaMin U","a9","L1300-38","in 10mM Water","DMF,CFDA",null,null,"Gastroenterology","Vitamin","Metabolism","Vitamin U (Methylmethioninesulfonium Chloride, Cabagin-U, Smethylmethionine) is a vitamin found in green vegetables. It is used in the treatment of peptic ulcers, colitis, and gastritis and has an effect on secretory, acid-forming, and enzymatic functions of the intestinal tract.",199.7,"3493-12-7","<1",0,39,195.29,"http://selleckchem.com/products/vitamin-u.html","C6H14NO2.Cl","chloride","Methylmethioninesulfonium Chloride, Cabagin-U, Smethylmethionine","[Cl-].C[S+](C)CCC(N)C(O)=O",0,0,0,0]
["S4821","Glycine","b9","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017,IP2010","017865,016784,017633,018315,018522","Neurological Disease/Inflammation","Others","Others","Glycine (2-Aminoacetic acid, Aminoacetic acid, Glycocoll) is a non-essential, non-polar, non-optical, glucogenic amino acid that is primarily found in gelatin and silk fibroin. It is involved in the body's production of DNA, phospholipids and collagen, and in release of energy.",75.07,"56-40-6","<1",0,15,199.81,"http://selleckchem.com/products/glycine.html","C2H5NO2","free base","2-Aminoacetic acid, Aminoacetic acid, Glycocoll","NCC(O)=O",-3.645,1,1,1]
["S4827","Manganese chloride","c9","L1300-38","in 10mM Water","FDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","018962","Metabolic Disease","Others","Others","Manganese chloride occurs in nature as the mineral. It is used as a precursor for other manganese compounds.",125.84,"7773-01-5",0,0,100,794.66,"http://selleckchem.com/products/manganese-chloride.html","MnCl2","free base","N/A","Cl[Mn]Cl",0.971,0,0,0]
["S4828","Sodium carbonate","d9","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,BP2016,USP39-NF34,JP16,IP2010","018519,018904","Others","Others","Others","Sodium Carbonate (Disodium carbonate, Soda Ash, Carbonic acid disodium salt) is the disodium salt of carbonic acid with alkalinizing property.",105.99,"497-19-8","<1",0,21,198.13,"http://selleckchem.com/products/sodium-carbonate.html","Na2CO3",0,"Disodium carbonate, Soda Ash, Carbonic acid disodium salt","[Na]OC(=O)O[Na]",0.394,3,0,2]
["S4950","L(+)-Asparagine monohydrate","e9","L1300-38","in 10mM Water","DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017",null,"Nutritional support","Others","Others","L-asparagine is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue, being used for a variety of pharmaceutical applications.",150.13,"5794-13-8","<1",0,30,199.83,"http://www.selleckchem.com/products/l-asparagine-monohydrate.html","C4H8N2O3.H2O","monohydrate","N/A","O.NC(CC(N)=O)C(O)=O",-4.615,2,2,3]
["S4951","L-Threonine","f9","L1300-38","in 10mM Water","DMF","JP17,BP2013",null,"Metabolic Disease","Others","Others","L-Threonine is an essential amino acid which is in its active form. It is important for the formation of collagen, elastin, and tooth enamel, and aids liver and lipotropic function when combined with aspartic acid and methionine.",119.12,"72-19-5","<1",0,23,193.08,"http://www.selleckchem.com/products/l-threonine.html","C4H9NO3","Free Base","N/A","CC(O)C(N)C(O)=O",-3.672,1,2,2]
["S4972","Choline Glycerophosphate","g9","L1300-38","in 10mM Water",null,"Martindale the Extra Pharmacopoei",null,"Others","Others","Others","Choline Glycerophosphate (Glycerophosphorylcholine) is a choline derivative and one of the two major forms of choline storage (along with phosphocholine) in the cytosol.",257.22,"28319-77-9",2,7.78,51,198.27,"http://selleckchem.com/products/choline-glycerophosphate.html","C8H20NO6P",0,"Glycerophosphorylcholine","C[N+](C)(C)CCO[P]([O-])(=O)OCC(O)CO",-4.131,2,2,8]
["S4993","Timonacic","h9","L1300-38","in 10mM Water",null,"Martindale:The Extra Pharmacopoeia",null,"Infection","Others","Others","Timonacic (Thiazolidine-4-carboxylic acid, Detoxepa, Hepalidine, 1,3-Thiazolidine-4-carboxylic acid) is a cyclic sulfur amino acid derivative with potential antineoplastic and antioxidant activities.",133.17,"444-27-9",1,7.51,27,202.75,"http://www.selleckchem.com/products/timonacic.html","C4H7NO2S","Free Base","Thiazolidine-4-carboxylic acid, Detoxepa, Hepalidine, 1,3-Thiazolidine-4-carboxylic acid","OC(=O)C1CSCN1",-2.889,1,1,1]
["S5048","Fosfomycin Disodium","a10","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,JP17,BP2017","050717","Infection","Antibiotics,Bacterial","Microbiology","Fosfomycin (Phosphonemycin) is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an early stage in cell wall synthesis.",182.02,"26016-99-9","<1",0,36,197.78,"http://selleckchem.com/products/fosfomycin-disodium.html","C3H5O4P.2Na","sodium","Phosphonemycin Disodium","[Na+].[Na+].CC1OC1[P]([O-])([O-])=O",-2.496,1,0,1]
["S5051","Pipemidic acid","b10","L1300-38","in 10mM Water","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17",null,"Gastroenterology/Infection","Antibiotics,Bacterial","Microbiology","Pipemidic acid (Acido pipemidico) is a pyridopyrimidine antibiotic derivative of piromidic acid with activity against gram-negative and some gram-positive bacteria.",303.32,"51940-44-4","<1",0,60,197.81,"http://selleckchem.com/products/pipemidic-acid.html","C14H17N5O3","free base","Acido pipemidico","CCN1C=C(C(O)=O)C(=O)C2=CN=C(N=C12)N3CCNCC3",-2.335,4,1,3]
["S5097","Methotrexate disodium","c10","L1300-38","in 10mM Water","DMF,HMA","Martindale:The Extra Pharmacopoeia",null,"Cancer/Hematology/Immunology/Inflammation","Dehydrogenase,DHFR","Metabolism","Methotrexate sodium, an inhibitor of tetrahydrofolate dehydrogenase, is an antineoplastic antimetabolite with immunosuppressant properties.",498.4,"7413-34-5","<1",0,99,198.64,"http://selleckchem.com/products/methotrexate-disodium.html","C20H20N8O5.2Na","disodium salt","N/A","[Na+].[Na+].CN(CC1=NC2=C(N)N=C(N)N=C2N=C1)C3=CC=C(C=C3)C(=O)NC(CCC([O-])=O)C([O-])=O",-2.834,5,3,9]
["S5107","Riboflavin phosphate sodium","d10","L1300-38","in 10mM Water","PMDA",null,null,"Others","Others","Others","Flavin mononucleotide (riboflavin-5'-phosphate, FMN) is a biomolecule produced from riboflavin (vitamin B2) by the enzyme riboflavin kinase and functions as prosthetic group of various oxidoreductases including NADH dehydrogenase as well as cofactor in biological blue-light photo receptors.",478.33,"130-40-5","<1",0,39,81.53,"http://selleckchem.com/products/flavin-mononucleotide.html","C17H20N4NaO9P","phosphate sodium","Flavin mononucleotide, riboflavin-5'-phosphate, FMN, Vitamin B2 Phosphate Sodium Salt","[Na+].CC1=CC2=C(C=C1C)N(CC(O)C(O)C(O)CO[P](O)([O-])=O)C3=NC(=O)NC(=O)C3=N2",0,0,0,0]
["S5124","DL-Citrulline","e10","L1300-38","in 10mM Water","NDC","USP43-NF38",null,"Metabolic Disease","Others","Others","L-Citrulline (Citrulline, Cit) is a naturally occurring nonessential amino acid which is the key intermediate in the urea cycle.",175.19,"627-77-0","<1",0,35,199.78,"http://selleckchem.com/products/dl-citrulline.html","C6H13N3O3","free base","Citrulline","NC(CCCNC(N)=O)C(O)=O",0,0,0,0]
["S5131","Homotaurine","f10","L1300-38","in 10mM Water","DMF",null,null,"Neurological Disease","GABA Receptor","Neuronal Signaling","Homotaurine (Tramiprosate, Alzhemed, 3-Amino-1-propanesulfonic acid) is a synthetic organic compound that has GABAergic activity by mimicking GABA. It is a GABAA partial agonist as well as a GABAB receptor partial agonist with low efficacy.",139.17,"3687-18-1",0,0,27,194.01,"http://selleckchem.com/products/homotaurine.html","C3H9NO3S","free base","Tramiprosate, Alzhemed, 3-Amino-1-propanesulfonic acid","NCCC[S](O)(=O)=O",0,0,0,0]
["S5136","Calcium folinate","g10","L1300-38","in 10mM Water","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,EP9.7,KP Ⅹ,Ph.Int_6th,BP2017,IP2010",null,"Cancer","DHFR","Metabolism","Calcium folinate (Leucovorin calcium, Folinic acid calcium salt, Wellcovorin) is a metabolically active, reduced form of folic acid that is rapidly absorbed and extensively metabolized in the liver to other folic acid derivatives.",511.5,"1492-18-8","<1",0,100,195.5,"http://selleckchem.com/products/calcium-folinate.html","C20H21N7O7.Ca","calcium salt","Leucovorin calcium, Folinic acid calcium salt, Wellcovorin","[Ca++].NC1=NC(=C2N(C=O)C(CNC3=CC=C(C=C3)C(=O)NC(CCC([O-])=O)C([O-])=O)CNC2=N1)O",0,0,0,0]
["S5220","D-Pantethine","h10","L1300-38","in 10mM Water","DMF","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17",null,"Cardiovascular Disease","Vitamin","Metabolism","Pantethine (Bis-pantethine, Pantetina, Pantomin, Pantosin) is a naturally occurring compound synthesized in the body from pantothenic acid (vitamin B5) via addition of cysteamine and used as a dietary supplement for lowering blood cholesterol and triglycerides.",554.72,"16816-67-4","<1",0,100,180.27,"http://selleckchem.com/products/d-pantethine.html","C22H42N4O8S2","free base","Bis-pantethine, Pantetina, Pantomin, Pantosin","CC(C)(CO)C(O)C(=O)NCCC(=O)NCCSSCCNC(=O)CCNC(=O)C(O)C(C)(C)CO",-1.938,4,8,19]
["S5252","Ozagrel sodium","a11","L1300-38","in 10mM Water","CFDA,PMDA","JP17",null,"Hematology","P450 (e.g. CYP17),Prostaglandin Receptor","Metabolism","Ozagrel sodium (KCT-0809, Cataclot, Xanbo) is a thromboxane A2 synthase (CYP5) inhibitor with neuroprotective properties.",250.23,"189224-26-8",1,4,50,199.82,"http://selleckchem.com/products/ozagrel-sodium.html","C13H11N2O2.Na","sodium","KCT-0809, Cataclot, Xanbo","[Na+].[O-]C(=O)\\C=C\\C1=CC=C(C[N]2C=CN=C2)C=C1",0.13,1,0,4]
["S5267","Nylidrin Hydrochloride","b11","L1300-38","in 10mM Water","DMF",null,null,"Angiology","Adrenergic Receptor","Neuronal Signaling","Nylidrin Hydrochloride (Buphenine), a β-adrenergic agonist, is used therapeutically for its vasodilating effect on the peripheral circulation and possibly on the cerebral circulation as well.",335.87,"849-55-8",0,0,67,199.48,"https://www.selleckchem.com/products/nylidrin-hydrochloride.html","C19H25NO2.HCl","hydrochloride","Buphenine HCl","Cl.CC(CCC1=CC=CC=C1)NC(C)C(O)C2=CC=C(O)C=C2",4.112,0,3,7]
["S5296","Cephradine monohydrate","c11","L1300-38","in 10mM Water","DMF","USP42-NF37",null,"Infection","Antibiotics,Bacterial","Microbiology","Cefradine is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.",367.42,"75975-70-1","<1",0,4,10.89,"http://selleckchem.com/products/cephradine-monohydrate.html","C16H19N3O4S.H2O","hydrate","N/A","O.CC1=C(N2C(SC1)C(NC(=O)C(N)C3=CCC=CC3)C2=O)C(O)=O",-2.484,3,2,4]
["S5362","Citicoline","d11","L1300-38","in 10mM Water","DMF, CFDA, PMDA","USP43-NF38, JP17",null,"Psychotic disorders","Others","Others","Citicoline (CDP-choline, cytidine 5'-diphosphocholine) is a naturally occurring compound that acts as nutrient with a broad spectrum of benefits for conditions associated with symptoms of neurological dysfunction. As an endogenous compound, it is also an essential intermediate in the synthesis of cell membrane phospholipids and its formation is the rate-limiting step in phosphatidylcholine synthesis.",488.32,"987-78-0","<1",0,97,198.64,"https://www.selleckchem.com/products/citicoline.html","C14H26N4O11P2","inner salt","CDP-choline, cytidine 5'-diphosphocholine","C[N+](C)(C)CCO[P]([O-])(=O)O[P](O)(=O)OCC1OC(C(O)C1O)N2C=CC(=NC2=O)N",-5.406,6,3,10]
["S5384","UTP Trisodium Salt","e11","L1300-38","in 10mM Water","DMF",null,null,"Others","DNA/RNA Synthesis","DNA Damage/DNA Repair","Uridine-5'-triphosphate (UTP) is a pyrimidine nucleoside triphosphate and a substrate for the synthesis of RNA during transcription.",550.09,"19817-92-6","<1",0,100,181.79,"http://selleckchem.com/products/utp-trisodium-salt.html","C9H15N2O15P3.3Na","Trisodium salt","N/A","[Na+].[Na+].[Na+].OC1C(O)C(OC1CO[P]([O-])(=O)O[P]([O-])(=O)O[P](O)([O-])=O)N2C=CC(=O)NC2=O",-7.518,6,3,8]
["S5412","Loxoprofen Sodium","f11","L1300-38","in 10mM Water","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ, JP17",null,"Inflammation","Immunology & Inflammation related","Immunology & Inflammation","Loxoprofen sodium is a non-steroidal anti-inflammatory drug.",268.28,"80382-23-6","<1",0,53,197.55,"https://www.selleckchem.com/products/loxoprofen-sodium.html","C15H17O3.Na","sodium salt","N/A","[Na+].CC(C([O-])=O)C1=CC=C(CC2CCCC2=O)C=C1",1.462,1,0,4]
["S5433","Sodium succinate","g11","L1300-38","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia","080516","Others","Others","Others","Sodium succinate (Sodium 3-carboxypropanoate, Disodium butanedioate) is the sodium salt form of succinate, which is an important metabolite at the cross-road of several metabolic pathways and involved in the formation and elimination of reactive oxygen species.",162.05,"150-90-3","<1",0,32,197.47,"http://selleckchem.com/products/sodium-succinate.html","C4H4O4.2Na","disodium salt","Sodium 3-carboxypropanoate, Disodium butanedioate","[Na+].[Na+].[O-]C(=O)CCC([O-])=O",-3.308,0,0,3]
["S5496","Guanethidine Monosulfate","h11","L1300-38","in 10mM Water","FDA,DMF","USP42-NF37,EP9.1,BP2017","086113,086114","Cardiovascular Disease","Adrenergic Receptor","Neuronal Signaling","Guanethidine monosulfate is an antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves.",296.39,"645-43-2","<1",0,59,199.06,"http://selleckchem.com/products/guanethidine-monosulfate.html","C10H22N4.H2SO4","sulfate","N/A","NC(=N)NCCN1CCCCCCC1.O[S](O)(=O)=O",0.579,0,2,4]
["S5524","Spermine Tetrahydrochloride","a2","L1300-39","in 10mM Water","NDC",null,null,"Nutritional support","Others","Others","Spermine (Gerontine, Neuridine, Musculamine) is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is a major natural intracellular compound capable of protecting DNA from free radical attack.",348.18,"306-67-2","<1",0,69,198.17,"http://selleckchem.com/products/spermine-tetrahydrochloride.html","C10H26N4.4HCl","tetrahydrochloride","Gerontine tetrahydrochloride, Neuridine tetrahydrochloride, Musculamine tetrahydrochloride","Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN",0.024,0,4,11]
["S5526","β-Alanine","b2","L1300-39","in 10mM Water",null,"BP2019;IP2010",null,"Others","Others","Others","β-Alanine (beta-Alanine, 3-Aminopropanoic acid) is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotransmitter by activating glycine and GABA receptors.",89.09,"107-95-9","<1",0,17,190.82,"http://www.selleckchem.com/products/beta-alanine.html","C3H7NO2","Free Base","beta-Alanine, 3-Aminopropanoic acid","NCCC(O)=O",-3.397,1,1,2]
["S5533","Tobramycin sulfate","c2","L1300-39","in 10mM Water","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ","050789,062945,063080,063100,063111,063112,063113,063117,063118,063119,063120,063121,063122,063127,063128,063161,064021,064026,065013,065122,065407,205179,205685,206965","Infection","Antibiotics,Bacterial","Microbiology","Tobramycin sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity.",1425.42,"49842-07-1","<1",0,100,70.15,"https://www.selleckchem.com/products/tobramycin-sulfate.html","C36H84N10O38S5","free base",0,"NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)CC1O.NCC4OC(OC5C(N)CC(N)C(OC6OC(CO)C(O)C(N)C6O)C5O)C(N)CC4O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O",-16.755,8,20,12]
["S5545","DL-Serine","d2","L1300-39","in 10mM Water",null,"Martindale:The Extra Pharmacopoeia",null,"Others","PKM","Metabolism","Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2.",105.09,"302-84-1","<1",0,8,76.13,"http://selleckchem.com/products/dl-serine.html","C3H7NO3",0,"N/A","NC(CO)C(O)=O",-4.049,1,2,2]
["S5549","DL-Arginine","e2","L1300-39","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","BP2010;USP32-NF27","016931","Nutritional support","Others","Others","Arginine is an α-amino acid that is used in the biosynthesis of proteins and plays an important role in cell division, wound healing, removing ammonia from the body, immune function, and the release of hormones.",174.2,"7200-25-1","<1",0,34,195.18,"http://selleckchem.com/products/dl-arginine.html","C6H14N4O2","free base","N/A","NC(CCCNC(N)=N)C(O)=O",-3.831,1,3,6]
["S5571","L-Asparagine","f2","L1300-39","in 10mM Water","DMF,CFDA,NDC","USP42-NF37",null,"Nutritional support","Others","Others","L-Asparagine (2-Aminosuccinamic acid, alpha-aminosuccinamic acid) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.",132.12,"70-47-3","<1",0,26,196.79,"http://selleckchem.com/products/l-asparagine.html","C4H8N2O3","free base","2-Aminosuccinamic acid, alpha-aminosuccinamic acid","NC(CC(N)=O)C(O)=O",-4.408,2,2,3]
["S5588","Creatine","g2","L1300-39","in 10mM Water","DMF,CFDA","Martindale:The Extra Pharmacopoeia",null,"Nutritional support","IFN,JAK","JAK/STAT","Creatine (Methylguanidoacetic acid) is a nitrogenous organic acid that occurs naturally in vertebrates. It facilitates the recycling of adenosine triphosphate (ATP) primarily in muscle and brain tissue.Creatine can inhibits the JAK-STAT1 signal transmission by inhibiting the interaction of IFN-γ receptors with JAK2 in an ATP-independent manner, thereby inhibiting downstream pro-inflammatory gene expression.",131.13,"57-00-1","<1",0,26,198.28,"http://selleckchem.com/products/creatine.html","C4H9N3O2","free base","Methylguanidoacetic acid","CN(CC(O)=O)C(N)=N",-1.095,1,1,3]
["S5628","L-Valine","h2","L1300-39","in 10mM Water","DMF,NDC","KP Ⅹ,JP17",null,"Metabolic Disease/Neurological Disease","Others","Others","Valine is a branched-chain essential amino acid that has stimulant activity and promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.",117.15,"72-18-4","<1",0,23,196.33,"http://selleckchem.com/products/l-valine.html","C5H11NO2","free base","N/A","CC(C)C(N)C(O)=O",-2.318,1,1,2]
["S5629","L-Proline","a3","L1300-39","in 10mM Water","DMF,NDC","JP17",null,"Cardiovascular Disease","Others","Others","L-Proline is one of non-essential amino acids and an essential component of collagen that is important for proper functioning of joints and tendons.",115.13,"147-85-3","<1",0,23,199.77,"http://selleckchem.com/products/l-proline.html","C5H9NO2","free base","N/A","OC(=O)C1CCCN1",-2.843,1,1,1]
["S5630","L-lysine","b3","L1300-39","in 10mM Water","DMF,NDC","USP42-NF37,JP17",null,"Infection","Others","Others","Lysine is an α-amino acid that is used in the biosynthesis of proteins and is required for growth and tissue repair.",146.19,"56-87-1","<1",0,29,198.37,"http://selleckchem.com/products/l-lysine.html","C6H14N2O2","free base","N/A","NCCCCC(N)C(O)=O",-3.24,1,2,5]
["S5631","L-Alanine","c3","L1300-39","in 10mM Water","DMF,NDC","JP17",null,"Others","Others","Others","Alanine is a naturally occuring non-essential amino acid that is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brainR, and the CNS.",89.09,"56-41-7","<1",0,17,190.82,"http://selleckchem.com/products/l-alanine.html","C3H7NO2","free base","N/A","CC(N)C(O)=O",-3.161,1,1,1]
["S5632","L-aspartic Acid","d3","L1300-39","in 10mM Water","DMF,NDC,HMA","USP42-NF37,JP17",null,"Cardiovascular Disease","Others","Others","L-aspartic Acid is one of non-essential amino acids and may be a neurotransmitter.",133.1,"56-84-8","<1",0,8,60.11,"http://selleckchem.com/products/l-aspartic-acid.html","C4H7NO4","free base","N/A","NC(CC(O)=O)C(O)=O",-3.78,2,1,3]
["S5633","L-methionine","e3","L1300-39","in 10mM Water","DMF,CFDA,NDC","EP9.2,JP17,Ph.Int_5th,BP2013",null,"Others","Others","Others","L-Methionine is an essential sulfur-containing, free-form amino acid, acts as an antioxidant promoter, and contributes to the synthesis of S-adenosyl-L-methionine (SAMe).",149.21,"63-68-3","<1",0,29,194.36,"http://selleckchem.com/products/l-methionine.html","C5H11NO2S","free base","N/A","CSCCC(N)C(O)=O",-2.834,1,1,4]
["S5634","L-arginine","f3","L1300-39","in 10mM Water","DMF,CFDA,NDC","JP17,IP2010",null,"Nutritional support","Others","Others","Arginine is an important amino acid used in the biosynthesis of proteins. L-arginine plays an important role in immune regulation by affecting the immune response and inflammation. It is also implicated in cell division, wound healing and the release of hormones.",174.2,"74-79-3","<1",0,34,195.18,"http://selleckchem.com/products/l-arginine.html","C6H14N4O2","free base","N/A","NC(CCCNC(N)=N)C(O)=O",-3.831,1,3,6]
["S5635","L-cysteine","g3","L1300-39","in 10mM Water","DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,EP9.2,JP17",null,"Others","Others","Others","Cysteine is a naturally occurring, sulfur-containing amino acid which is important for protein synthesis, detoxification, and also exerts diverse metabolic functions.",121.16,"52-90-4","<1",0,24,198.09,"http://selleckchem.com/products/l-cysteine.html","C3H7NO2S","free base","N/A","NC(CS)C(O)=O",-3.078,1,1,2]
["S5660","Clodronate disodium tetrahydrate","h3","L1300-39","in 10mM Water","DMF","EP9.1,BP2015",null,"Cancer/Metabolic Disease","Others","Others","Clodronate disodium tetrahydrate (clodronic acid) is a diphosphonate which affects calcium metabolism. It inhibits bone resorption and soft tissue calcification.",360.92,"88416-50-6","<1",0,72,199.49,"https://www.selleckchem.com/products/clodronate-disodium-tetrahydrate.html","CH10Cl2Na2O10P2","free base","clodronic acid disodium tetrahydrate","O.O.O.O.[Na+].[Na+].O[P]([O-])(=O)C(Cl)(Cl)[P](O)([O-])=O",-2.534,0,0,2]
["S5674","Lodoxamide Tromethamine","a4","L1300-39","in 10mM Water","FDA,CFDA,NDC",null,"020191","Inflammation/Ophthalmology","Immunology & Inflammation related","Immunology & Inflammation","Lodoxamide Tromethamine (Alomide, Lodoxamidetromethamine) is the tromethamide salt form of lodoxamide, a synthetic mast cell stabilizing compound with anti-inflammatory activity.",553.9,"63610-09-3","<1",0,19,34.3,"http://www.selleckchem.com/products/lodoxamide-tromethamine.html","C19H28ClN5O12","tromethamide salt","Alomide, Lodoxamidetromethamine","NC(CO)(CO)CO.NC(CO)(CO)CO.OC(=O)C(=O)NC1=C(Cl)C(=CC(=C1)C#N)NC(=O)C(O)=O",-9.554,4,10,10]
["S5706","Edetate Trisodium","b4","L1300-39","in 10mM Water","FDA,DMF,CFDA,NDC,HMA",null,"008922","Hematology","Others","Others","Edetate Trisodium (EDTA trisodium salt, ethylenediaminetetraacetic acid) is the organic sodium salt of ethylenediaminetetraacetic acid (EDTA). EDTA is a chelating agent capable of removing a heavy metal, such as lead or mercury, from the blood.",358.19,"150-38-9","<1",0,36,100.51,"https://www.selleckchem.com/products/edetate-trisodium.html","C10H13N2Na3O8","free base","EDTA Trisodium, ethylenediaminetetraacetic acid Trisodium","[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O",-9.072,1,0,11]
["S5721","Edetate calcium disodium","c4","L1300-39","in 10mM Water","FDA,DMF,NDC","USP38-NF33","008922","Hematology","Others","Others","Edetate (EDTA) calcium disodium is a chelating agent that is primarily used for the management of severe lead poisoning.",374.27,"62-33-9","<1",0,75,200.39,"http://www.selleckchem.com/products/edetate-calcium-disodium.html","C10H12CaN2Na2O8","disodium salt","EDTA calcium disodium","[Na+].[Na+].[Ca++].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O",-7.512,0,0,11]
["S5746","pentetate calcium trisodium hydrate","d4","L1300-39","in 10mM Water","FDA,NDC,PMDA","EP9.3;BP2019","021749","Others","Others","Others","pentetate calcium trisodium hydrate (Ca-DTPA) is an iron chelating agent.",497.35,"207226-35-5","<1",0,100,201.07,"http://www.selleckchem.com/products/pentetate-calcium-trisodium-hydrate.html","C14H18CaN3Na3O10.xH2O","trisodium hydrate","Ca-DTPA","[Na+].[Na+].[Na+].[Ca++].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O",-8.631,0,0,16]
["S5801","Ala-Gln","e4","L1300-39","in 10mM Water","DMF","USP43-NF38",null,"Inflammation","Others","Others","Ala-Gln (l-alanyl-l-glutamine), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals with better solubility and stability than glutamine (Gln).",217.22,"39537-23-0","<1",0,43,197.96,"http://www.selleckchem.com/products/ala-gln.html","C8H15N3O4","Free Base","l-alanyl-l-glutamine","CC(N)C(=O)NC(CCC(N)=O)C(O)=O",-4.543,3,3,6]
["S5820","L-Hydroxyproline","f4","L1300-39","in 10mM Water","NDC",null,null,"Others","Others","Others","L-Hydroxyproline (trans-4-Hydroxy-L-proline) is a collagen-specific amino acid. It is used as a diagnostic marker of bone turnover and liver fibrosis.",131.13,"51-35-4",1,7.63,26,198.28,"http://www.selleckchem.com/products/l-hydroxyproline.html","C5H9NO3","Free Base","trans-4-Hydroxy-L-proline","OC1CNC(C1)C(O)=O",-3.934,1,2,1]
["S5866","Gastrodenol","g4","L1300-39","in 10mM Water","marketed in Spain",null,null,"Gastroenterology/Inflammation","Others","Others","Gastrodenol (Bismuth tripotassium dicitrate) is used to treat certain conditions caused by too much acid being produced in the stomach, such as stomach ulcers and ulcers of the upper part of the intestine (duodenal ulcers).",704.47,"57644-54-9",1,1.42,100,141.95,"https://www.selleckchem.com/products/gastrodenol.html","C12H10BiK3O14","Free Base","Bismuth tripotassium dicitrate","[K+].[K+].[K+].[BiH6+3].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O",-11.482,0,0,10]
["S5867","Bendazac L-lysine","h4","L1300-39","in 10mM Water","CFDA","Martindale:The Extra Pharmacopoeia",null,"Inflammation","Others","Others","Bendazac L-lysine has a protective effect against lens protein denaturation both in vitro and in vivo. It is also a nonsteroidal anti-inflammatory drug (NSAID) used for joint and muscular pain.",428.48,"81919-14-4",3,7,86,200.71,"https://www.selleckchem.com/products/bendazac-l-lysine.html","C22H28N4O5","Free Base","N/A","NCCCCC(N)C(O)=O.OC(=O)COC1=N[N](CC2=CC=CC=C2)C3=C1C=CC=C3",-2.452,4,2,10]
["S6023","Creatine monohydrate","a5","L1300-39","in 10mM Water","CFDA,DMF","Martindale:The Extra Pharmacopoeia",null,"Nutritional support","Others","Others","Creatine (Methylguanidoacetic acid) is a key player in the phosphagen energy system, the primary source of ATP during short-term, high intensity activities.",149.15,"6020-87-7",0,0,5.96,39.94,"http://www.selleck.cn/products/creatine-monohydrate.html","C4H11N3O3","monohydrate","Methylguanidoacetic acid monohydrate","O.CN(CC(O)=O)C(N)=N",-1.302,1,1,3]
["S6102","Thiamine pyrophosphate hydrochloride","b5","L1300-39","in 10mM Water","CFDA, NDC",null,null,"Others","Vitamin","Metabolism","Thiamine pyrophosphate hydrochloride (cocarboxylase) is a thiamine (vitamin B1) derivative which is produced by the enzyme thiamine diphosphokinase. It is a coenzyme of many enzymes, most of which occur in prokaryotes and is involved in the regulation of basic metabolism.",460.77,"154-87-0",0,0,92,199.67,"http://www.selleck.cn/products/thiamine-pyrophosphate-hydrochloride.html","C12H19ClN4O7P2S","hydrochloride","cocarboxylase hydrochloride","[Cl-].CC1=NC=C(C[N+]2=CSC(=C2C)CCO[P](O)(=O)O[P](O)(O)=O)C(=N1)N",-1.984,4,1,8]
["S6201","Malachite green","c5","L1300-39","in 10mM Water",null,"EP9.2;BP2017;IP2010",null,"Others","Others","Others","Malachite green (Aniline green, Basic green 4, Diamond green B, Victoria green B) is a synthetic dyestuff and antimicrobial with potential carcinogenicity.",927,"2437-29-8",0,0,185.4,200,"http://www.selleck.cn/products/malachite-green.html","C52H54N4O12","free base","Aniline green, Basic green 4, Diamond green B, Victoria green B","CN(C)C1=CC=C(C=C1)C(C2=CC=CC=C2)=C3C=CC(C=C3)=[N+](C)C.CN(C)C4=CC=C(C=C4)C(C5=CC=CC=C5)=C6C=CC(C=C6)=[N+](C)C.OC(=O)C(O)=O.OC(=O)C([O-])=O.OC(=O)C([O-])=O",5.289,4,0,9]
["S6224","(R)-Serine","d5","L1300-39","in 10mM Water","CFDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,Ph.Int_6th,JP17",null,"Others","NMDAR","Neuronal Signaling","(R)-Serine is the R-enantiomer of serine, which is used in the biosynthesis of proteins. (R)-Serine acts as obligatory coagonist at the glycine site associated with the N-methyl-D-aspartate subtype of glutamate receptors (NMDAR) and has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration.",105.09,"312-84-5",0,0,21.02,200,"http://www.selleck.cn/products/r-serine.html","C3H7NO3","free base","N/A","NC(CO)C(O)=O",-4.049,1,2,2]
["S6266","(S)-Glutamic acid","e5","L1300-39","in 10mM Water","CFDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017,IP2010",null,"Inflammation/Psychotic disorders","GluR","Neuronal Signaling","(S)-Glutamic acid (L-Glutamic acid) is an endogenous, non-selective glutamate receptor agonist.",147.13,"56-86-0",0,0,4,27.19,"http://www.selleck.cn/products/s-glutamic-acid.html","C5H9NO4","free base","L-Glutamic acid","NC(CCC(O)=O)C(O)=O",-3.459,2,1,4]
["S6315","Sodium phytate hydrate","f5","L1300-39","in 10mM Water","CFDA",null,null,"Others","Others","Others","Sodium phytate hydrate (Phytic acid, Dodecasodium phytate, Myo-inositol hexakis, Inositol hexakisphosphate) functions as a storage depot and precursor for other inositol phosphates and pyrophosphates. It can be used clinically as a hypocalcemic agent and a complexing agent for removal of traces of heavy metal ions.",660.04,"14306-25-3",0,0,62.22,94.27,"http://www.selleck.cn/products/sodium-phytate-hydrate.html","C6H18O24P6.xNa.yH2O","hydrate","Phytic acid sodium hydrate, Dodecasodium phytate, Myo-inositol hexakis, Inositol hexakisphosphate","O[P](O)(=O)OC1C(O[P](O)(O)=O)C(O[P](O)(O)=O)C(O[P](O)(O)=O)C(O[P](O)(O)=O)C1O[P](O)(O)=O",-2.026,6,0,12]
["S6445","Chlorophyllin (sodium copper salt)","g5","L1300-39","in 10mM Water","CFDA","Martindale the Extra Pharmacopoei,USP42-NF37",null,"Others","Others","Others","Chlorophyllin, the sodium and copper salt of chlorophyll, is an antioxidant and antimutagenic agent.",724.15,"11006-34-1","<1",0,13,17.95,"http://www.selleck.cn/products/chlorophyllin.html","C34H31CuN4Na3O6","sodium copper salt","N/A","[Na+].[Na+].[Na+].[Cu++]|1|2|3|[N-]4C5=C(C)C(=C4C=C6N|1=C(C=C7[N-]|2C(=C(CC([O-])=O)C8=N|3C(=C5)C(C)C8CCC([O-])=O)C(=C7C)C([O-])=O)C(=C6C)CC)C=C",-1.452,0,0,8]
["S6460","Sugammadex (sodium)","h5","L1300-39","in 10mM Water","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale the Extra Pharmacopoei","022225","Neurological Disease","Others","Others","Sugammadex (ORG-25969) is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery in adults.",2178.01,"343306-79-6","<1",0,100,45.91,"http://www.selleck.cn/products/sugammadex.html","C72H104Na8O48S8","sodium","ORG-25969","[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].OC1C(O)C2OC3OC(CSCCC([O-])=O)C(OC4OC(CSCCC([O-])=O)C(OC5OC(CSCCC([O-])=O)C(OC6OC(CSCCC([O-])=O)C(OC7OC(CSCCC([O-])=O)C(OC8OC(CSCCC([O-])=O)C(OC9OC(CSCCC([O-])=O)C(OC1OC2CSCCC([O-])=O)C(O)C9O)C(O)C8O)C(O)C7O)C(O)C6O)C(O)C5O)C(O)C4O)C(O)C3O",-18.704,16,16,40]
["S6488","Gadoxetate sodium","a6","L1300-39","in 10mM Water","FDA,CFDA,NDC,PMDA","Martindale the Extra Pharmacopoei","022090","Diagnosis","Others","Others","Gadoxetate is a paramagnetic gadolinium-containing contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection.",725.71,"135326-22-6",0,0,100,137.8,"http://www.selleck.cn/products/gadoxetate-sodium.html","C23H28GdN3Na2O11","sodium","N/A","[Na+].[Na+].[Gd+3]|1|2|3|4|5|6|7|[O-]C(=O)CN|1(CCN|2(CC([O-]|3)=O)CC([O-]|4)=O)CC(CC8=CC=C(OCC)C=C8)N|5(CC([O-]|6)=O)CC([O-]|7)=O",-3.48,1,0,4]
["S6592","Diquafosol Tetrasodium","b6","L1300-39","in 10mM Water","Marketed in Japan",null,null,"Ophthalmology","P2 Receptor","Neuronal Signaling","Diquafosol Tetrasodium (INS-365), a P2Y2 receptor agonist, is a pharmaceutical drug for the treatment of dry eye disease.",878.23,"211427-08-6",0,0,100,113.87,"http://www.selleck.cn/products/diquafosol-tetrasodium.html","C18H22N4Na4O23P4","Tetrasodium","INS-365","[Na+].[Na+].[Na+].[Na+].OC1C(O)C(OC1CO[P]([O-])(=O)O[P]([O-])(=O)O[P]([O-])(=O)O[P]([O-])(=O)OCC2OC(C(O)C2O)N3C=CC(=O)NC3=O)N4C=CC(=O)NC4=O",-11.332,11,6,14]
["S7548","Rilmenidine Phosphate","c6","L1300-39","in 10mM Water","marketed in Hungary, Poland and the Czech Republic","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Imidazoline Receptor","GPCR & G Protein","Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used for the treatment of hypertension.",278.24,"85409-38-7",1,3.59,55,197.67,"http://selleckchem.com/products/rilmenidine-phosphate.html","C10H19N2O5P","Phosphate","N/A","O[P](O)(O)=O.C1CN=C(NC(C2CC2)C3CC3)O1",1.296,2,1,4]
["S7785","Pemetrexed Disodium Hydrate","d6","L1300-39","in 10mM Water","DMF","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017",null,"Cancer/Respiratory Disease","Apoptosis related,Autophagy,DHFR","Metabolism","Pemetrexed Disodium Hydrate (LY-231514) is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively. Pemetrexed Disodium Hydrate stimulates autophagy and apoptosis.",516.42,"357166-30-4","<1",0,100,193.64,"http://selleckchem.com/products/pemetrexed-disodium-hydrate.html","C20H21N5O6.5/2H2O.2Na","Disodium Hydrate","LY-231514 Disodium Hydrate","NC1=NC(=O)C2=C([NH]C=C2CCC3=CC=C(C=C3)C(=O)NC(CCC(=O)O[Na])C(=O)O[Na])N1",2.06,7,4,11]
["S9344","DL-Methionine","e6","L1300-39","in 10mM Water","DMF","Martindale:The Extra Pharmacopoeia,EP9.2,Ph.Int_6th,BP2013",null,"Nutritional support","Antiviral","Microbiology","DL-Methionine is an amino acid that has a role in the defence of oxidative stress.",149.21,"59-51-8",0,0,6,40.21,"https://www.selleckchem.com/products/dl-methionine.html","C5H11NO2S","free base",0,"CSCCC(N)C(O)=O",-2.834,1,1,4]
["S9353","L-serine","f6","L1300-39","in 10mM Water","DMF","JP17,BP2015",null,"Others","Others","Others","L-serine, one of the so-called non-essential amino acids, plays a central role in cellular proliferation.",105.09,"56-45-1",0,0,21,199.82,"https://www.selleckchem.com/products/l-serine.html","C3H7NO3","free base",0,"NC(CO)C(O)=O",-4.049,1,2,2]
["S9367","Adenosine disodium triphosphate hydrate","g6","L1300-39","in 10mM Water","CFDA","CP2005",null,"Cardiovascular Disease","Others","Others","Adenosine disodium triphosphate hydrate(ATP disodium) is the sodium salt form of adenosine triphosphate (ATP), a complex organic chemical that provides energy to drive many processes in living cells., ,",551.14,"34369-07-8",0,0,100,181.44,"https://www.selleckchem.com/products/adenosine-disodium-triphosphate.html","C10H14N5Na2O13P3.xH2O","disodium triphosphate hydrate","ATP disodium","O[C@H]1([C@H](N2C3C(N=C2)=C(N)N=CN=3)O[C@H](CO[P](O[P](O[P](=O)(O)O)(=O)O)(=O)O)[C@@H](O)1).[Na].O",-5.474,7,3,8]
["P1004","Bivalirudin Trifluoroacetate","h6","L1300-39","in 10mM Water","FDA,DMF,EMA,HMA,CFDA,NDC",null,"090189,090811,090816,091206,091468,091602,201577,202471,204876,205962,206551,210031","Cardiovascular Disease/Hematology",0,"Angiogenesis","Bivalirudin Trifluoroacetate is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin.",2180.33,"128270-60-0",0,0,0,10,"http://www.selleckchem.com/peptide/bivalirudin-trifluoroacetate.html","C98H138N24O33","Trifluoroacetate","D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH","CCC(C)C(NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CC(N)=O)NC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)C2CCCN2C(=O)C(CCCNC(N)=N)NC(=O)C3CCCN3C(=O)C(N)CC4=CC=CC=C4)C(=O)N5CCCC5C(=O)NC(CCC(O)=O)C(=O)NC(CCC(O)=O)C(=O)NC(CC6=CC=C(O)C=C6)C(=O)NC(CC(C)C)C(O)=O",0,0,0,0]
["P1011","Eptifibatide Acetate","a7","L1300-39","in 10mM Water","DMF","Martindale:The Extra Pharmacopoeia",null,"Hematology","5-alpha Reductase","Angiogenesis","Eptifibatide Acetate is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue. A disulfide bridge forms between mercaptopropionyl and cysteine. Eptifibatide prevents platelet aggregation. One study shows the inhibition of platelet glycoprotein IIb/IIIa in acute coronary syndromes.",832.4,"148031-34-9",0,0,0,10,"http://selleckchem.com/products/eptifibatide-acetate.html","C35H49N11O9S2","Acetate","Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2","NC(=N)NCCCCC1NC(=O)CCSSCC(NC(=O)C2CCCN2C(=O)C(CC3=C[NH]C4=C3C=CC=C4)NC(=O)C(CC(O)=O)NC(=O)CNC1=O)C(N)=O",0,0,0,0]
["P1017","Octreotide (SMS 201-995) acetate","b7","L1300-39","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","075957,075959,076330,077329,077330,077331,077372,077373,077450,090986,091041,203765,204669","Endocrinology",0,"Neuronal Signaling","Octreotide (SMS 201-995) acetate is the acetate salt of a cyclic octapeptide. It is a long-acting octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin.","1019.28 (free base)","79517-01-4",0,0,0,10,"http://selleckchem.com/products/octreotide-acetate.html","C49H66N10O10S2.xC2H4O2","Acetate","D-Phe-c[Cys-Phe-D-Trp-Lys-Thr-Cys]-Thr-ol","CC(O)C(CO)NC(=O)C1CSSCC(NC(=O)C(N)CC2=CC=CC=C2)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=C[NH]C5=C4C=CC=C5)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)N1",0,0,0,0]
["P1025","Atosiban Acetate","c7","L1300-39","in 10mM Water","CFDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Neurological Disease",0,"Angiogenesis","Atosiban Acetate is a competitive oxytocin and vasopressin antagonist by exhibiting high affinity for both receptors. It is used to treat preterm labors.",994.2,"90779-69-4",0,0,0,10,"http://www.selleckchem.com/peptide/atosiban-acetate.html","C43H67N11O12S2","Acetate","c[Mpr-D-Tyr(OEt)-Ile-Thr-Asn-Cys]-Pro-Orn-Gly-NH2","CCOC1=CC=C(CC2NC(=O)CCSSCC(NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(NC2=O)C(C)CC)C(C)O)C(=O)N3CCCC3C(=O)NC(CCCN)C(=O)NCC(N)=O)C=C1",0,0,0,0]
["P1029","Oxytocin (Syntocinon)","d7","L1300-39","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,BP2017,JP17,IP2010","018243,018248,077453,091676,200219","Endocrinology",0,"Angiogenesis","Oxytocin(Syntocinon) is a nine amino acid peptide that is synthesized in hypothalamic neurons and transported down axons of the posterior pituitary for secretion into blood.",1067.2,"50-56-6",0,0,0,10,"http://selleckchem.com/products/Oxytocin-Acetate(Syntocinon).html","C45H70N12O14S2","Free Base","H-Cys(1)-Tyr-Ile-Gln-Asn-Cys(1)-Pro-Leu-Gly-NH2","CCC(C)C1NC(=O)C(CC2=CC=C(O)C=C2)NC(=O)C(N)CSSCC(NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC1=O)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(N)=O.CC(O)=O",0,0,0,0]
["P1030","Salmon Calcitonin Acetate","e7","L1300-39","in 10mM Water","DMF,EMA",null,null,"Cancer/Metabolic Disease",0,0,"Salmon Calcitonin Acetate, which is more potent and longer lasting than human CT, has been used widely for the treatment of osteoporosis, paget's disease, hypercalcemic shock and chronic pain in terminal cancer patients.",3431.85,"47931-85-1",0,0,0,10,"http://www.selleckchem.com/peptide/salmon-calcitonin-acetate.html","C145H240N44O48S2","Acetate",0,"CC(C)CC(NNC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)C(=O)C(CC1=CC=C(O)C=C1)NN2CCCC2C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)O)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CO)C(=O)NCC(=O)NC(C(C)O)C(=O)N3CCCC3C(N)=O)C(=O)C(=O)C(CCCCN)NC(=O)C(CC4=CN=C[NH]4)NC(=O)C(CC(C)C)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(N)=O)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(NC(=O)C5CSSCC(N)C(=O)NC(CO)C(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)N5)C(C)C",0,0,0,0]
["P1034","Terlipressin Acetate","f7","L1300-39","in 10mM Water","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Angiology","5-alpha Reductase","Angiogenesis","Terlipressin Acetate is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. It has been found to be effective when norepinephrine does not help.",1227.37,"14636-12-5",0,0,0,10,"http://selleckchem.com/products/terlipressin-acetate.html","C52H74N16O15S2",0,"Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2(Cys4-Cys9)","NCCCCC(NC(=O)C1CCCN1C(=O)C2CSSCC(NC(=O)CNC(=O)CNC(=O)CN)C(=O)NC(CC3=CC=C(O)C=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)N2)C(=O)NCC(N)=O",0,0,0,0]
["P1039","Somatostatin Acetate","g7","L1300-39","in 10mM Water","CFDA,DMF","Martindale the Extra Pharmacopoei",null,"Others","5-alpha Reductase","Neuronal Signaling","Somatostatin Acetate is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones.",1637.88,"38916-34-6",-1,0,100,61.05,"http://www.selleck.cn/products/somatostatin-acetate.html","C76H104N18O19S2","Free Base","Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH(Cys3-Cys14)","CC(N)C(=O)NCC(=O)NC1CSSCC(NC(=O)C(CO)NC(=O)C(NC(=O)C(CC2=CC=CC=C2)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(CC3=C[NH]C4=CC=CC=C34)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(CC6=CC=CC=C6)NC(=O)C(CC(N)=O)NC(=O)C(CCCCN)NC1=O)C(C)O)C(C)O)C(O)=O.CC(O)=O",-8.729,16,21,26]
["P1049","GHRP-2","h7","L1300-39","in 10mM Water","marketed in Japan",null,null,"Endocrinology",0,0,"GHRP-2 is a true hGH secretagogue. It is a synthetic agonist of ghrelin.",878,"158861-67-7",0,0,0,10,"http://selleckchem.com/products/GHRP-2-Acetate.html","C47H59N9O8","Free Base",0,"CC(N)C(=O)NC(CC1=CC=C2C=CC=CC2=C1)C(=O)NC(CC3=C[NH]C4=C3C=CC=C4)C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCCCN)C(N)=O",0,0,0,0]
["P1084","Desmopressin Acetate","a8","L1300-39","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","021795,074575,074830,074888,075220,076470,077122,077212,077414,091280,091374,200653,201831,204695,204751,207880,210371","Hematology","Vasopressin Receptor","GPCR & G Protein","Desmopressin is a synthetic octapeptide, and an analogue of human hormone arginine vasopressin with antidiuretic and coagulant activities. It is a selective agonist for the vasopressin V2 receptor (V2R).",1129.27,"62288-83-9",0,0,0,10,"https://www.selleckchem.com/products/desmopressin-acetate-.html","C46H64N14O12S2.C2H4O2","Acetate","N/A","CC(O)=O.NC(=N)NCCCC(NC(=O)C1CCCN1C(=O)C2CSSCCC(=O)NC(CC3=CC=C(O)C=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)N2)C(=O)NCC(N)=O",0,0,0,0]
["P1085","Angiotensin II human Acetate","b8","L1300-39","in 10mM Water","DMF",null,null,"Angiology","Angiotensin Receptor","GPCR & G Protein","Angiotensin II (angII) is an octapeptide hormone which affects the activities of heart, kidney, vasculature and brain. It works via binding to specific receptors present on cell membranes.",1106.23,"68521-88-0",0,0,0,10,"https://www.selleckchem.com/products/angiotensin-ii-human-acetate.html","C52H75N13O14",0,0,"CCC(C)C(NC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C(NC(=O)C(CCCNC(N)=N)NC(=O)C(N)CC(O)=O)C(C)C)C(=O)NC(CC2=C[NH]C=N2)C(=O)N3CCCC3C(=O)NC(CC4=CC=CC=C4)C(O)=O.CC(O)=O",0,0,0,0]
["P1087","Carperitide Acetate","c8","L1300-39","in 10mM Water","DMF,PMDA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","Others","Others","Caperitide acetate is a synthetic analog of human atrial natriuretic peptide (ANP) containing 28 amino acids. It acts as an inhibitor of endothelin-1 secretion when stimulated by angiotensin II (Ang II), likely through a cGMP-dependent mechanism.It induces natriuresis, diuresis, and vasodilation, effectively reducing blood volume and easing cardiac strain. By suppressing the renin-angiotensin-aldosterone system (RAAS), it aids in preventing myocardial remodeling and fibrosis, thereby enhancing cardiac function and decreasing the incidence of postoperative atrial fibrillation, heart failure, and stroke. Carperitide acetate inhibits endothelin-1 secretion in a dose-dependent way.",3140.49,"1366000-58-9",{"$nulls":3},{"v":10,"d":"10.00"},"https://www.selleckchem.com/products/carperitide-acetate.html","C129H207N45O41S3","Acetate",null,"CCC(C)C1NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(O)=O)NC(=O)C(CCSC)NC(=O)C(CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=CC=C2)NC(=O)C(CSSCC(NC(=O)CNC(=O)C(CC(C)C)NC(=O)CNC(=O)C(CO)NC(=O)C(CCC(N)=O)NC(=O)C(C)NC(=O)CNC1=O)C(=O)NC(CC(N)=O)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC4=CC=C(O)C=C4)C(O)=O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(C)C)NC(=O)C(N)CO.CC(O)=O",-19.837,32,46,75]
["S1671","(6-)ε-​Aminocaproic acid","d8","L1300-39","in 10mM Water","DMF",null,null,"Hematology","Others","Others","(6-)ε-​Aminocaproic acid is a derivative and analogue of the amino acid lysine.",131.17,"60-32-2",0,0,26,198.22,"http://selleckchem.com/products/Aminocaproic-acid(Amicar).html","C6H13NO2","free base","N/A","NCCCCCC(O)=O",-2.164,1,1,5]
["S3076","Foscarnet Sodium","e8","L1300-39","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,EP9.2,USP39-NF34,BP2015","077174","Infection","Reverse Transcriptase","Microbiology","Foscarnet Sodium (Phosphonoformate) inhibits viral RNA polymerases, reverse transcriptase, and DNA polymerases through noncompetitive inhibition with dNTPs.",191.95,"63585-09-1",0,0,3,15.63,"http://selleckchem.com/products/foscarnet-sodium.html","CNa3O5P","Sodium","Phosphonoformate","[Na+].[Na+].[Na+].[O-]C(=O)[P]([O-])([O-])=O",-4.033,0,0,1]
["S4519","Citric acid trilithium salt tetrahydrate","f8","L1300-39","in 10mM Water","FDA,DMF,HAHA,NDC,PMDA,HMA",null,"018421,070755","Metabolic Disease","Others","Others","Citric acid trilithium salt tetrahydrate (Trilithium citrate tetrahydrate, Lithium citrate tribasic tetrahydrate) is a pharmaceutical and construction material. It is commonly used in HPLC gradient elution for quantification of amino acids.",281.98,"6080-58-6",0,0,56,198.6,"http://selleckchem.com/products/citric-acid-trilithium-salt-tetrahydrate.html","C6H5Li3O7&bull;4H2O","free base","Trilithium citrate tetrahydrate, Lithium citrate tribasic tetrahydrate","O.O.O.O.[Li]OC(=O)CC(O)(CC(=O)O[Li])C(=O)O[Li]",-1.875,6,0,8]
["S5865","Hyaluronic acid","g8","L1300-39","in 10mM Water","DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia",null,"Immunology/Infection","Others","Others","Hyaluronic acid (HA, Hyaluronan, Hyaluronate) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is widely used in skin care.","N/A","9004-61-9",0,0,5,0,"http://www.selleckchem.com/products/hyaluronic-acid.html",0,"Free Base","Hyaluronan, Hyaluronate","CC(=O)NC1C(O[*])C(O)C(CO)OC1OC2C(O)C(O)C(O[*])OC2C(O)=O",-2.747,7,5,7]
["S4986","Latamoxef sodium","h8","L1300-39","in 10mM Water","CFDA,PMDA","KP Ⅹ,JP17",null,"Infection","Antibiotics,Bacterial","Microbiology","Latamoxef sodium (Moxalactam Disodium, FestamoxinLy, Shiomarin, Ly 127935, 6059 S) is an antibiotic and has anti-bacterial and anti-inflammation effects.",564.44,"64953-12-4",0,0,0,10,"https://www.selleckchem.com/products/latamoxef-sodium.html","C20H18N6Na2O9S",0,"Moxalactam Disodium, FestamoxinLy, Shiomarin, Ly 127935, 6059 S","[Na+].[Na+].COC1(NC(=O)C(C([O-])=O)C2=CC=C(O)C=C2)C3OCC(=C(N3C1=O)C([O-])=O)CSC4=NN=N[N]4C",-3.547,7,2,9]
["S2441","Estramustine phosphate sodium","a9","L1300-39","in 10mM Water","FDA,NDC,DMF","Martindale the Extra Pharmacopoei","018045","Cancer","Microtubule Associated","Cytoskeletal Signaling","Estramustine phosphate sodium (EMP, Emcyt, Estracyt) is an antitumour drug with a unique dual mode of action. Estrone and estradiol, products of the metabolism of estramustine phosphate sodium, have shown antigonadotrophic activity resulting in reduced testosterone levels. Estramustine(the cytotoxic metabolite produced by dephosphorylation of estramustine phosphate sodium) is an antiprostatic tumor drug with antimicrotubule effects.",564.35,"52205-73-9","<1",0,100,177.2,"http://www.selleck.cn/products/estramustine-phosphate-sodium.html","C23H30Cl2NNa2O6P","phosphate sodium","EMP, Emcyt, Estracyt","[Na+].[Na+].CC12CCC3C(CCC4=C3C=CC(=C4)OC(=O)N(CCCl)CCCl)C1CCC2O[P]([O-])([O-])=O",3.131,3,0,8]
["S3948","Spermine","b9","L1300-39","in 10mM Water","NDC",null,null,"Nutritional support","Others","Others","Spermine (4,9-Diaza-1,12-dodecanediamine) is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria.",202.34,"71-44-3",0,0,0,10,"http://selleckchem.com/products/spermine.html","C10H26N4","free base","4,9-Diaza-1,12-dodecanediamine","NCCCNCCCCNCCCN",-1.504,0,4,11]
["S2435","Sodium stibogluconate","c9","L1300-39","in 10mM Water","CFDA","Martindale:The Extra Pharmacopoeia, BP2020, Ph.Int_6th , IP2010",null,"Others","phosphatase","Metabolism","Sodium stibogluconate (SSG, Stibogluconate trisodium nonahydrate, Lenocta, VQD-001), a pentavalent antimony derivative, is a potent and selective inhibitor of protein tyrosine phosphatase (PTPase). Sodium stibogluconate inhibits 99% of Src homology 2 domain-containing phosphatase 1 (SHP-1) activity at 10 μg/ml and similar degrees of inhibition of SHP-2 and PTP1B requires 100 μg/ml. Sodium stibogluconate is a drug used in treatment of leishmaniasis.",907.88,"16037-91-5","<1",0,20,22.03,"http://www.selleckchem.com/products/sodium-stibogluconate.html","C12H35Na3O26Sb2","Sodium","SSG, Stibogluconate sodium, Stibogluconate trisodium nonahydrate, Lenocta, VQD-001","O.O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+].OCC(O)C1O[Sb]2(O)(OC1C(O2)C([O-])=O)O[Sb]34([O-])OC(C(O)CO)C(O3)C(O4)C([O-])=O",-8.931,7,4,8]
["S6831","HEPES","d9","L1300-39","in 10mM Water","DMF",null,null,"Others","Others","Others","HEPES is a zwitterionic sulfonic acid buffering agent, commonly used to uphold a neutral pH of basal medium within cell cultures.",238.3,"7365-45-9","<1",0,48,201.43,"http://www.selleckchem.com/products/hepes.html","C8H18N2O4S","Free Base","4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid","OCCN1CCN(CC1)CC[S](O)(=O)=O",-0.858,0,1,5]
["S4933","Lithium carbonate","e9","L1300-39","in 10mM Water","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,Ph.Int_5th,IP2010","016834,017812,018558,070407,072542,076121,076170,076243,076366,076382,076490,076691,076795,076823,076832,078715,078763,079139,079159,090702,091027,091544,091616,202219,202288,204445,204779,205532,205663","Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Lithium carbonate (Li2CO3) is an inorganic compound that is valuable and effective agent in the treatment and prophylaxis of mood disorders, particularly bipolar disorder (BD). Lithium carbonate is able to alter D2 dopamine receptors response.",73.89,"554-13-2",0,0,0,10,"https://www.selleckchem.com/products/lithium-carbonate.html","CLi2O3",0,"Li2CO3","[LiH].[Li]OOC=O",-0.347,2,0,2]
["S3203","D-Alanine","f9","L1300-39","in 10mM Water","DMF",null,null,"Others","NMDAR","Neuronal Signaling","D-alanine (Ala, (R)-Alanine, Ba 2776, D-α-Alanine, NSC 158286) is an endogenous co-agonist at the glycine site of the N-methyl-d-aspartate (NMDA) receptor.",89.09,"338-69-2","<1",0,18,202.04,"http://www.selleckchem.com/products/d-alanine.html","C3H7NO2","free base","Ala, (R)-Alanine, Ba 2776, D-α-Alanine, NSC 158286","CC(N)C(O)=O",-3.161,1,1,1]
["P1088","Lanreotide acetate","g9","L1300-39","in 10mM Water","DMF, NDC, FDA",null,"022074","Endocrinology/Metabolic Disease","GHSR","Endocrinology & Hormones","Lanreotide (Laromustine, Angiopeptin, BIM 23014, Dermopeptin, Ipstyl, ITM-014, Somatulina, Somatuline, Lanreotidum) acetate, an analog of the native somatostatin peptide, is a physiological inhibitor of growth hormone (GH). Lanreotide also has antitumoral effects.",1156.38,"2378114-72-6",-1,0,23,19.89,"https://www.selleckchem.com/products/lanreotide-acetate.html","C56H73N11O12S2","Acetate","Laromustine, Angiopeptin, BIM 23014, BIM 23014C, BM 23014, Dermopeptin, Ipstyl, ITM-014, ITM-014T, Somatulina, Somatuline, Lanreotidum","CC(C)C1NC(=O)C(CCCCN)NC(=O)C(CC2=C[NH]C3=C2C=CC=C3)NC(=O)C(CC4=CC=C(O)C=C4)NC(=O)C(CSSCC(NC1=O)C(=O)NC(C(C)O)C(N)=O)NC(=O)C(N)CC5=CC6=CC=CC=C6C=C5.CC(O)=O",-0.979,9,13,17]
["S3096","L-Histidine monohydrochloride monohydrate","h9","L1300-39","in 10mM Water","DMF, NDC","USP43-NF38, JP17",null,"Nutritional support","Others","Metabolism","L-Histidine monohydrochloride monohydrate (L-Histidine hydrochloride hydrate, H-His-OH.HCl.H2O), a structural analogue of the essential amino acid L-histidine, is a reversible inhibitor of protein biosynthesis which evokes disparate responses from non-tumorigenic and tumorigenic cells in culture.",209.63,"5934-29-2","<1",0,42,200.35,"https://www.selleckchem.com/products/l-histidine-monohydrochloride-monohydrate.html","C6H12ClN3O3","Monohydrate","L-Histidine hydrochloride hydrate, H-His-OH.HCl.H2O","O.Cl.NC(CC1=CN=C[NH]1)C(O)=O",-3.538,2,2,3]
["S3142","Potassium sorbate","a10","L1300-39","in 10mM Water",null,"EP10.4, USP43-NF38, IP2010",null,"Others","Bacterial","Microbiology","Potassium sorbate (Sorbic acid potassium) is a nonpoisonous food preservative isolated from Sorbus aucuparia. Potassium sorbate is an effective inhibitor of most molds and yeasts and some bacteria.",150.22,"24634-61-5","<1",0,30,199.71,"https://www.selleckchem.com/products/potassium-sorbate.html","C6H7KO2","Potassium","Sorbic acid potassium","[K+].C/C=C/C=C/C([O-])=O",-0.111,0,0,2]
["P1033","Teriparatide Acetate","b10","L1300-39","in 10mM Water","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","EP10.4, USP43-NF38","019498","Metabolic Disease","5-alpha Reductase","Angiogenesis","Teriparatide Acetate is a recombinant form of parathyroid hormone, used in the treatment of some forms of osteoporosis",4117.72,"52232-67-4",-1,0,100,24.29,"http://www.selleckchem.com/peptide/teriparatide-acetate.html","C181H291N55O51S2","Free Base","H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH","CCC(C)C(NC(=O)C(CCC(O)=O)NC(=O)C(CO)NC(=O)C(NC(=O)C(N)CO)C(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(CC1=CN=C[NH]1)C(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC2=CN=C[NH]2)C(=O)NC(CC(C)C)C(=O)NC(CC(N)=O)C(=O)NC(CO)C(=O)NC(CCSC)C(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)C)C(=O)NC(CCC(O)=O)C(=O)C(=O)C(CC3=C[NH]C4=C3C=CC=C4)NC(=O)C(CC(C)C)NNC(CCCNC(N)=N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CC(O)=O)C(=O)NC(C(C)C)C(=O)NC(CC5=CN=C[NH]5)C(=O)NC(CC(N)=O)C(=O)NC(CC6=CC=CC=C6)C(O)=O.CC(O)=O",-24.309,47,53,148]
["P1047","Felypressin Acetate","c10","L1300-39","in 10mM Water",null,"EP10.5",null,"Angiology","5-alpha Reductase","Angiogenesis","Felypressin-Acetate is a non-catecholamine vasoconstrictor that is chemically associated to vasopressin, the posterior pituitary hormone.",1040.22,"56-59-7",-1,0,100,96.13,"http://www.selleckchem.com/peptide/felypressin-acetate.html","C46H65N13O11S2","Free Base","H-[Cys-Phe-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2","NCCCCC(NC(=O)C1CCCN1C(=O)C2CSSCC(N)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)N2)C(=O)NCC(N)=O",-3.938,11,12,19]
["S1314","Zoledronic acid (ZOL 446)","d10","L1300-39","in 10mM Water","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","EP10.4, IP2010","078475","Cancer/Metabolic Disease","Apoptosis related,Autophagy,Ras,Rho","Cell Cycle","Zoledronic acid (ZA, Zoledronate, CGP-4244, GP42446A, ZOL 446, Zometa, Zomera, Aclasta, Reclast), a potent osteoclast inhibitor, induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho. Zoledronic acid (ZA) also induces autophagy.",272.09,"118072-93-8","<1",0,4,14.7,"http://www.selleckchem.com/products/Zoledronic-Acid.html","C5H10N2O7P2","Free Base","ZA, Zoledronate, CGP-4244, GP42446A, ZOL 446, Zometa, Zomera, Aclasta, Reclast","OC(C[N]1C=CN=C1)([P](O)(O)=O)[P](O)(O)=O",-1.209,1,0,4]
["S3497","Gadobutrol","e10","L1300-39","in 10mM Water","FDA, DMF, PMDA","EP10.5","201277","Diagnosis","Others","Others","Gadobutrol (Gadovist, Gadavist,ZK 135079) is a non-ionic macrocyclic gadolinium-based contrast agent (GBCA) that is usedfor tissue contrast enhancement in magnetic resonance imaging (MRI).",604.71,"138071-82-6","<1",0,100,165.37,"http://www.selleckchem.com/products/gadobutrol.html","C18H31GdN4O9","Free Base","Gadovist, Gadavist,ZK 135079","[Gd+3].OCC(O)C(CO)N1CCN(CCN(CCN(CC1)CC([O-])=O)CC([O-])=O)CC([O-])=O",-6.984,0,3,10]
["S4383","Bekanamycin","f10","L1300-39","in 10mM Water",null,"JP17",null,"Infection","Others","Others","Bekanamycin is an aminoglycoside antibiotic.",483.51,"4696-76-8","<1",0,96,198.55,"http://www.selleckchem.com/products/bekanamycin.html","C18H37N5O10","Free Base","Kanamycin B","NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)C(O)C1O",-7.433,4,11,6]
["S4443","Piperazine adipate","g10","L1300-39","in 10mM Water","DMF","EP10.4, USP42-NF37, KP Ⅹ, Ph.Int_6th, JP16,IP2010",null,"Gastroenterology","Parasite","Microbiology","Piperazine adipate is a broad spectrum anthelmintic agent that inhibits malate oxidation in Ascaridia galli and Heterakis gallinae.",232.28,"142-88-1","<1",0,43,185.12,"http://www.selleckchem.com/products/piperazine-adipate.html","C10H20N2O4","Free Base","N/A","OC(=O)CCCCC(O)=O.C1CNCCN1",-5.651,2,2,5]
["S4494","Methionine","h10","L1300-39","in 10mM Water","DMF, CFDA, NDC","EP10.5, USP43-NF38,",null,"Nutritional support","GABA Receptor","Neuronal Signaling","Methionine (MRX-1024, D-Methionine) is an activitor of GABAA receptor that modulates neuronal activity.",149.21,"348-67-4","<1",0,29,194.36,"http://www.selleckchem.com/products/methionine.html","C5H11NO2S","Free Base","MRX-1024, D-Methionine","CSCCC(N)C(O)=O",-2.834,1,1,4]
["S4857","L-Ornithine","a11","L1300-39","in 10mM Water","DMF, CFDA, NDC",null,null,"Nutritional support","Others","Others","L-ornithine ((S)-2,5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle.",132.16,"70-26-8","<1",0,26,196.73,"http://www.selleckchem.com/products/l-ornithine.html","C5H12N2O2","Free Base","(S)-2,5-Diaminopentanoic acid","NCCCC(N)C(O)=O",-3.697,1,2,4]
["S4879","Tenofovir hydrate","b11","L1300-39","in 10mM Water","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","Ph.Int_6th, IP2010","078800","Infection","Antiviral,Reverse Transcriptase","Microbiology","Tenofovir (GS-1278) hydrate blocks reverse transcriptase and hepatitis B virus infections.",305.23,"206184-49-8","<1",0,10,32.76,"http://www.selleckchem.com/products/tenofovir-hydrate.html","C9H16N5O5P","Hydrate","GS-1278 hydrate","O.CC(C[N]1C=NC2=C(N)N=CN=C12)OC[P](O)(O)=O",-0.979,4,1,5]
["S5000","Gadodiamide","c11","L1300-39","in 10mM Water","FDA, DMF, NDC, PMDA","EP10.5, USP43-NF38","020123","Diagnosis","Others","Others","Gadodiamide (GDD, Omniscan) is a widely used magnetic resonance imaging (MRI) contrast agent with a high renal toxicity.",573.66,"131410-48-5","<1",0,100,174.32,"http://www.selleckchem.com/products/gadodiamide.html","C16H26GdN5O8","Free Base","Omniscan, GDD","[Gd+3].CNC(=O)CN(CCN(CCN(CC([O-])=O)CC(=O)NC)CC([O-])=O)CC([O-])=O",-7.261,2,2,16]
["S5022","Varenicline Hydrochloride","d11","L1300-39","in 10mM Water","FDA, DMF, EMA, NDC, PMDA",null,"201920","Others","AChR","Neuronal Signaling","Varenicline (CP 526555) Hydrochloride is a potent and selective inhibitor of nicotine acetylcholine receptor (nAChR) with Ki of 0.12 nM and 0.14 nM for α6β2 nAChR and α4β2 nAChR, respectively.",247.72,"230615-23-3","<1",0,50,201.84,"http://www.selleckchem.com/products/varenicline-hydrochloride.html","C13H14ClN3","Hydrochloride","CP 526555 hydrochloride","Cl.C1NCC2CC1C3=CC4=NC=CN=C4C=C23",1.42,2,1,0]
["S5198","Sodium Etidronate","e11","L1300-39","in 10mM Water","FDA, DMF, CFDA, PMDA","EP10.5, USP43-NF38, JP17","075800","Inflammation","phosphatase","Metabolism","Sodium Etidronate (Didronel, EHDP, Etidronic acid) is a non-aminobisphosphonate that exhibits protein tyrosine phosphatase (PTP) inhibitory activity.",249.99,"7414-83-7","<1",0,50,200.01,"http://www.selleckchem.com/products/sodium-etidronate.html","C2H6Na2O7P2","Sodium","Didronel, EHDP, Etidronic acid","[Na+].[Na+].CC(O)([P](O)([O-])=O)[P](O)([O-])=O",-3.649,0,0,2]
["S5260","ATP","f11","L1300-39","in 10mM Water","DMF, NDC",null,null,"Nutritional support","Immunology & Inflammation related","Immunology & Inflammation","ATP (Adenosine-Triphosphate, Adenosine 5'-triphosphate) is a multifunctional nucleoside triphosphate and an important endogenous signaling molecule in immunity and inflammation.",507.18,"56-65-5","<1",0,100,197.17,"http://www.selleckchem.com/products/atp.html","C10H16N5O13P3","Free Base","Adenosine-Triphosphate, Adenosine 5'-triphosphate","NC1=C2N=C[N](C3OC(CO[P](O)(=O)O[P](O)(=O)O[P](O)(O)=O)C(O)C3O)C2=NC=N1",-2.526,7,3,8]
["S5330","Amikacin Sulfate Salt","g11","L1300-39","in 10mM Water","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP17, IP2010","063167","Infection","Antibiotics,Bacterial","Microbiology","Amikacin (BAY 41-6551) sulfate, a semisynthetic analog of kanamycin, is an aminoglycoside antibiotic which is very active against most gram-negative bacteria including gentamicin- and tobramycin-resistant strains.",683.68,"149022-22-0","<1",0,100,146.27,"http://www.selleckchem.com/products/amikacin-sulfate-salt.html","C22H45N5O17S","Sulfate Salt","BAY 41-6551 sulfate","NCCC(O)C(=O)NC1CC(N)C(OC2OC(CN)C(O)C(O)C2O)C(O)C1OC3OC(CO)C(O)C(N)C3O.O[S](O)(=O)=O",-9.033,5,13,10]
["S5956","Dexamethasone phosphate disodium","h11","L1300-39","in 10mM Water","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","USP42-NF37, KP Ⅹ, Ph.Int_6th, JP17, Ph.Int_5th, JP16, IP2010","040069","Infection/Inflammation","Glucocorticoid Receptor","Endocrinology & Hormones","Dexamethasone phosphate disodium (DEX, Dexacort, Decadron, Dexair, Hexadrol, Maxidex) is a glucocorticoid receptor agonist with both anti-inflammatory and anti-oxidative effects.",516.4,"2392-39-4","<1",0,100,193.65,"http://www.selleckchem.com/products/dexamethasone-phosphate-disodium.html","C22H28FNa2O8P","Disodium","DEX, Dexacort, Decadron, Dexair, Hexadrol, Maxidex, Dexamethasone 21-phosphate disodium salt","[Na+].[Na+].CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO[P]([O-])([O-])=O",-0.541,3,1,4]
["S5964","Gatifloxacin hydrochloride","a2","L1300-40","in 10mM Water","FDA, DMF, CFDA, NDC, PMDA","IP2010","079084","Infection","Topoisomerase","DNA Damage/DNA Repair","Gatifloxacin (AM-1155, CG5501, BMS-206584, PD135432) hydrochloride is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases with IC50 of 13.8 μg/ml and 0.109 μg/ml for S. aureus topoisomerase IV and E. coli DNA gyrase, respectively.",411.86,"121577-32-0",4,9.71,20,48.56,"http://www.selleckchem.com/products/gatifloxacin-hydrochloride.html","C19H23ClFN3O4","Hydrochloride","AM-1155 hydrochloride, CG5501 hydrochloride, BMS-206584 hydrochloride, PD135432 hydrochloride","Cl.COC1=C2N(C=C(C(O)=O)C(=O)C2=CC(=C1N3CCNC(C)C3)F)C4CC4",-0.527,3,1,4]
["S5968","Kasugamycin hydrochloride hydrate","b2","L1300-40","in 10mM Water","CFDA",null,null,"Infection","Antibiotics","Immunology & Inflammation","Kasugamycin (Ksg) hydrochloride hydrate, an antibiotic which binds both the 30S and 70S ribosome, specifically inhibits translation initiation of canonical but not of leaderless messenger RNAs.",433.84,"200132-83-8","<1",0,87,200.53,"http://www.selleckchem.com/products/kasugamycin-hydrochloride-hydrate.html","C14H28ClN3O10","Hydrochloride hydrate","Ksg hydrochloride hydrate","O.Cl.CC1OC(OC2C(O)C(O)C(O)C(O)C2O)C(N)CC1NC(=N)C(O)=O",-6.382,3,7,5]
["S6446","Sodium citrate dihydrate","c2","L1300-40","in 10mM Water","CFDA, NDC, PMDA","USP43-NF38",null,"Others","Others","Others","Sodium citrate dehydrate (Trisodium citrate dihydrate, Citric acid trisodium salt dihydrate) is the preferred anticoagulant.",294.1,"6132-04-3","<1",0,59,200.61,"http://www.selleckchem.com/products/sodium-citrate-dihydrate.html","C6H9Na3O9","Dihydrate","Trisodium citrate dihydrate, Citric acid trisodium salt dihydrate","O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O",-6.156,0,0,5]
["S9794","Melittin","d2","L1300-40","in 10mM Water","FDA, DMF, NDC",null,null,"Immunology","Phospholipase (e.g. PLA)","Metabolism","Melittin (MLT, Forapin, Forapine) is an activator of phospholipase A2 (PLA2) that stimulates the activity of the low molecular weight PLA2, while it does not the increase the activity of the high molecular weight enzyme.",2846.46,"20449-79-0, 37231-28-0",-1,0,100,35.13,"http://www.selleckchem.com/products/melittin.html","C131H229N39O31","Free Base","MLT, Forapin, Forapine","CCC(C)C(NC(=O)CN)C(=O)NCC(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CO)C(=O)NC(CC2=C[NH]C3=C2C=CC=C3)C(=O)C(=O)C(NC(=O)C(CCCCN)NNC(CCCNC(N)=N)C(=O)NC(CCCCN)C(=O)NC(CCCNC(N)=N)C(=O)NC(CCC(N)=O)C(=O)NC(CCC(N)=O)C(N)=O)C(C)CC",-6.576,28,39,101]
["S5962","DL-Penicillamine","e2","L1300-40","in 10mM Water","FDA, DMF, NDC",null,"019853","Metabolic Disease","Others","Others","DL-Penicillamine (DL-beta-Mercaptovaline, 3,3-Dimethyl-DL-cysteine, 3-Sulfanylvaline, Cuprimine, Depen, DL-PenA, DL-P) induces alteration of elastic fibers of periosteum-perichondrium and associates growth inhibition.",149.21,"52-66-4","<1",0,30,201.06,"http://www.selleckchem.com/products/dl-penicillamine.html","C5H11NO2S","Free Base","DL-beta-Mercaptovaline, 3,3-Dimethyl-DL-cysteine, 3-Sulfanylvaline, Cuprimine, Depen, DL-PenA","CC(C)(S)C(N)C(O)=O",-2.496,1,1,2]
["S6991","Sodium Acetate","f2","L1300-40","in 10mM Water","FDA, DMF, CFDA, NDC, PMDA","USP–NF 2021(Issue 2), EP10.5, KP Ⅹ, JP17, IP2010","018893","others","Others","Others","Sodium acetate is an organic sodium salt. It contains an acetate.",82.03,"127-09-3","<1",0,16,195.05,"N/A","CH3COONa","Free Base","N/A","[Na+].CC([O-])=O",-1.679,0,0,0]
["S6992","Calcium chloride","g2","L1300-40","in 10mM Water","FDA, DMF, CFDA, NDC, PMDA","USP–NF 2021(Issue 2), EP10.5, KP Ⅹ, JP17, IP2010",203477,"others","Others","Others","Calcium chloride is an odorless, white, crystalline solid compound that is highly soluble in water.",110.98,"10043-52-4","<1",0,22,198.23,"N/A","CaCl2","Free Base","N/A","[Cl-].[Cl-].[Ca++]",-5.348,0,0,0]
["S9489","Sodium citrate","h2","L1300-40","in 10mM Water","FDA, DMF, CFDA, NDC, PMDA","USP–NF 2021(Issue 2), EP10.5, KP Ⅹ, Ph.Int_6th, JP17, IP2010","075503","others","Others","Others","Sodium citrate dehydrate (Trisodium citrate dihydrate, Citric acid trisodium salt dihydrate) is the preferred anticoagulant.",258.07,"68-04-2","<1",0,52,201.5,"N/A","C6H5Na3O7","Free Base","N/A","[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O",-5.741,0,0,5]
["E0375","Ammonium ferric citrate","a3","L1300-40","in 10mM Water","CFDA","USP–NF 2021(Issue 2), EP10.5, IP2010",null,"Others","Ferroptosis","Apoptosis","Ammonium ferric citrate (Ferric ammonium citrate, Ammonium iron(III) citrate, Iron ammonium citrate, FerriSeltz) induces ferroptosis in non-small-cell lung carcinoma through the inhibition of GPX4-GSS/GSR-GGT axis activity.",978.05,"1185-57-5","<1",0,53,54.19,"http://www.selleckchem.com/products/ammonium-ferric-citrate.html","C24H32Fe3N3O28","Citrate","Ferric ammonium citrate, Ammonium iron(III) citrate, Iron ammonium citrate, FerriSeltz","[NH4+].[NH4+].[NH4+].[Fe+3].[Fe+3].[Fe+3].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O",-28.54,0,0,20]
["P1104","Glatiramer acetate","b3","L1300-40","in 10mM Water","FDA, PMDA, NDC",null,"091646","Immunology","Immunology & Inflammation related","Immunology & Inflammation","Glatiramer acetate is a synthetic copolymer composed of a random mixture of four amino acids that modifies the immune response.",623.65,"147245-92-9","<1",0,100,160.35,"http://www.selleckchem.com/products/glatiramer-acetate.html","C25H45N5O13","Acetate","N/A","CC(N)C(O)=O.CC(O)=O.NCCCCC(N)C(O)=O.NC(CCC(O)=O)C(O)=O.NC(CC1=CC=C(O)C=C1)C(O)=O",-14.39,6,6,13]
["S6289","Gentamicin","c3","L1300-40","in 10mM Water","FDA,CFDA,PMDA,NDC","USP28-NF23,JP15","062289","Infection","Antiviral","Microbiology","Gentamicin, an aminoglycoside class of bactericidal antibiotic, is effective against gram-negative bacterial infections.",1390.71,"1403-66-3","<1",0,100,71.91,"http://www.selleckchem.com/products/gentamicin.html","C60H123N15O21","free base",0,"CNC(C)C1CCC(N)C(O1)OC2C(N)CC(N)C(OC3OCC(C)(O)C(NC)C3O)C2O.CNC4C(O)C(OCC4(C)O)OC5C(N)CC(N)C(OC6OC(CN)CCC6N)C5O.CNC7C(O)C(OCC7(C)O)OC8C(N)CC(N)C(OC9OC(CCC9N)C(C)N)C8O",-12.679,12,21,19]
["S6872","Merbromin","d3","L1300-40","in 10mM Water","CFDA,PMDA","JP16",null,"Infection","3C-Like Protease,Bacterial","Proteases","Merbromin (Mercurochrome), a xanthene dye and an antibacterial agent, is the first of a series of antiseptics that contained mercury, also is a mixed-type inhibitor of 3CLpro due to its ability of increasing the KM and decreasing the Kcat of 3CLpro.",752.68,"129-16-8","<1",0,100,132.86,"http://www.selleckchem.com/products/merbromin.html","C20H10Br2HgO6.2Na","free base","Mercurochrome, Merbromine, Mercurocol, Sodium mercurescein, Asceptichrome, Supercrome, Brocasept, Cinfacromin","[NaH].[NaH].O[Hg]C1=C(O)C(=CC2=C1OC3=CC(=C(Br)C=C3C24OC(=O)C5=C4C=CC=C5)O)Br",4.622,3,2,1]
["E0510","Cidofovir hydrate","e3","L1300-40","in 10mM Water","FDA,EMA,NDC,DMF",null,"201276,202501","Ophthalmology","DNA/RNA Synthesis","DNA Damage/DNA Repair","Cidofovir hydrate is a selective inhibitor of viral DNA synthesis through the selective inhibition of viral DNA polymerase.",315.22,"149394-66-1","<1",0,4,12.69,"http://www.selleckchem.com/products/cidofovir-hydrate.html","C8H14N3O6P.2H2O","Dihydride",0,"O.O.NC1=NC(=O)N(CC(CO)OC[P;v5](O)(O)=O)C=C1",-2.59,3,2,6]
["E0511","Framycetin sulphate","f3","L1300-40","in 10mM Water","HMA,DMF","BP2024;EP11.0;Martindale: The Complete Drug Reference",null,"Infection","DNA/RNA Synthesis","DNA Damage/DNA Repair","Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM, and competes for specific divalent metal ion binding sites in RNase P RNA, also inhibits hammerhead ribozyme with a Ki of 13.5 μM.",712.72,"4146-30-9","<1",0,100,140.31,"http://www.selleckchem.com/products/framycetin-sulphate.html","C23H48N6O17S","sulphate",0,"NCC1OC(OC2C(N)CC(N)C(O)C2OC3OC(CO)C(OC4OC(CN)C(O)C(O)C4N)C3O)C(N)C(O)C1O.O[S](O)(=O)=O",-8.832,6,13,9]
["E0525","Colistin","g3","L1300-40","in 10mM Water","FDA,EMA,CFDA,PMDA,HMA,DMF,NDC",null,"050355,050356","Infection","Anti-infection","Microbiology","Colistin(Polymyxin E), a cyclic polypeptide antibiotic synthesized by Bacillus polymyxa subspecies colistinus Koyama, exerts antimicrobial activity by targeting at the bacterial cell membrane.",1155.43,"1066-17-7","<1",0,100,86.55,"http://www.selleckchem.com/products/colistimethate.html","C52H98N16O13","free base","Polymyxin E","NA","NA","NA","NA","NA"]
["E0532","Menotropin","h3","L1300-40","in 10mM Water","DMF","JP18",null,"Endocrinology","Estrogen/progestogen Receptor","Endocrinology & Hormones","Menotropin (Human Menopausal Gonadotrophin) is a hormonally active medication for the treatment of fertility disturbances, which are extracted from the urine of postmenopausal women.",142.24,"61489-71-2","<1",0,28,196.85,"http://www.selleckchem.com/products/menotropin.html","C9H18O","free base","Human Menopausal Gonadotrophin","CC(C)(C)CCCCC=O",2.767,1,0,5]
["E0705","Flavin Adenine Dinucleotide Disodium","a4","L1300-40","in 10mM Water","PMDA","JP18",null,"Cardiovascular Disease","Others","Metabolism","Flavin Adenine Dinucleotide Disodium is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.",831.53,"84366-81-4","<1",0,100,120.26,"http://www.selleckchem.com/products/flavin-adenine-dinucleotide-disodium.html","C27H33N9O15P2.2Na","disodium salt",0,"[NaH].[NaH].CC1=C(C)C=C2N(CC(O)C(O)C(O)CO[P;v5](O)(=O)O[P;v5](O)(=O)OCC3OC(C(O)C3O)[N]4C=NC5=C(N)N=CN=C45)C6=NC(=O)NC(=O)C6=NC2=C1",-2.097,11,7,13]
["E2638","Tricine","b4","L1300-40","in 10mM Water",null,"EP10.8,IP2010",null,"Others","Others","Others","Tricine (N-[Tris(hydroxymethyl)methyl]glycine) is a buffer component for separation of low molecular weight peptides.",179.17,"5704-04-1","<1",0,36,200.93,"http://www.selleckchem.com/products/tricine.html","C6H13NO5","free base","N-[Tris(hydroxymethyl)methyl]glycine","OCC(CO)(CO)NCC(O)=O",-5.173,1,4,6]
["S3736","Fondaparinux Sodium (Org 31540)","c4","L1300-40","in 10mM Water","FDA,EMA,HMA,CFDA,PMDA,NDC,DMF",null,"208615,206918,206812,091316,021345","Cardiovascular Disease","Factor Xa","Metabolism","Fondaparinux Sodium (Org 31540, Natural heparin pentasaccharide, Fondaparin, SR-90107A) is a synthetic glucopyranoside with antithrombotic activity. It selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin; a synthetic inhibitor of Factor Xa.",1728.08,"114870-03-0",1,0.58,100,57.87,"http://www.selleckchem.com/products/fondaparinux-sodium.html","C31H43N3O49S8.10Na","Sodium salt","Natural heparin pentasaccharide Sodium, Fondaparin sodium, SR-90107A","[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].COC1OC(CO[S]([O-])(=O)=O)C(OC2OC(C(OC3OC(CO[S]([O-])(=O)=O)C(OC4OC(C(OC5OC(CO[S]([O-])(=O)=O)C(O)C(O)C5N[S]([O-])(=O)=O)C(O)C4O)C([O-])=O)C(O[S]([O-])(=O)=O)C3N[S]([O-])(=O)=O)C(O)C2O[S]([O-])(=O)=O)C([O-])=O)C(O)C1N[S]([O-])(=O)=O",-32.806,15,9,30]
["P1019","Cetrorelix Acetate","f4","L1300-40","in 10mM Water","FDA,EMA,CFDA,PMDA,DMF",null,"215737","Endocrinology","GNRH Receptor","Endocrinology & Hormones","Cetrorelix Acetate (NS 75A Acetate, SB 075 Acetate, SB 75 Acetate) is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH) with an IC50 of 1.21 nM.",1551.14,"130143-01-0","<1",0,100,64.47,"http://www.selleckchem.com/peptide/cetrorelix-acetate.html","C70H92ClN17O14.2(C2H4O2)","Acetate","Ac-3-(2-naphthyl)-D-Ala-4-Chloro-D-Phe-3(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2","CC(C)CC(NC(=O)C(CCCNC(N)=O)NC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C(CO)NC(=O)C(CC2=CN=CC=C2)NC(=O)C(CC3=CC=C(Cl)C=C3)NC(=O)C(CC4=CC5=CC=CC=C5C=C4)NC(C)=O)C(=O)NC(CCCN=C(N)N)C(=O)N6CCCC6C(=O)NC(C)C(N)=O.CC(O)=O.CC(O)=O",-0.13,16,16,38]
["E0149","Papain","g4","L1300-40","in 10mM Water","CFDA","USP–NF 2021(Issue 2), EP10.5, IP2010",null,"Others","Others","Others","Papain (papaya proteinase I) is a sulfhydryl protease from the latex of the papaya fruit. Papain breaks down intercellular matrix of cartilage.",226.23,"9001-73-4",0,0,0,10,"http://www.selleckchem.com/products/papain.html","C9H14N4O3","Free Base","papaya proteinase I","NCCC(=O)NC(CC1=CN=C[NH]1)C(O)=O",-4.41,3,3,6]
["S6482","Fosphenytoin (disodium)","h4","L1300-40","in 10mM Water","FDA,DMF,NDC,PMDA","Martindale the Extra Pharmacopoei,USP39-NF34","076886,077481,077989,078052,078126,078137,078158,078277,078417,078476,078736,078765,090099","Neurological Disease","Others","Others","Fosphenytoin (disodium) is the sodium salt form of fosphenytoin, a prodrug that is hydrolyzed to the anticonvulsant phenytoin upon parental administration.",406.24,"92134-98-0",0,0,0,10,"http://www.selleck.cn/products/fosphenytoin.html","C16H13N2Na2O6P","disodium","N/A","[Na+].[Na+].[O-][P]([O-])(=O)OCN1C(=O)NC(C1=O)(C2=CC=CC=C2)C3=CC=CC=C3",-0.495,3,1,5]
["S5961","Prednisolone disodium phosphate","a5","L1300-40","in 10mM Water","FDA,CFDA,PMDA,NDC,DMF","USP40-NF35,IP2010,JP16","204962,203559,080517","Inflammation;Immunology","Anti-infection","Microbiology","Prednisolone disodium phosphate (Hydeltrasol, Prednisolone 21-phosphate disodium) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties that exerts late mitogenic and biphasic effects on resistant acute lymphoblastic leukemia cells.",484.39,"125-02-0",0,0,0,10,"http://www.selleckchem.com/products/prednisolone-disodium-phosphate.html","C21H27Na2O8P","Phosphate","Hydeltrasol, Prednisolone 21-phosphate disodium","[Na+].[Na+].CC12CC(O)C3C(CCC4=CC(=O)C=CC34C)C1CCC2(O)C(=O)CO[P]([O-])([O-])=O",-0.989,3,1,4]
["E0178","Cysteamine bitartrate","b5","L1300-40","in 10mM Water","FDA,EMA,PMDA,DMF",null,"213491,211302,203389,200740,020392","Ophthalmology","Others","Others","Cysteamine bitartrate (Mercaptamine bitartrate) is an FDA-approved cystine-depleting aminothiol agent for the treatment of nephropathic cystinosis to decrease accumulation of lysosomal cystine by engaging in disulfide exchange. In addition, cysteamine bitartrate has antioxidant properties.",227.24,"27761-19-9",0,0,0,10,"http://www.selleckchem.com/products/cysteamine-bitartrate.html","C6H13NO6S","Bitartrate","Mercaptamine bitartrate","NCCS.OC(C(O)C(O)=O)C(O)=O",-4.359,2,3,4]
["E4227","D-Cysteine","c5","L1300-40","in 10mM Water","FDA",null,null,"Infection; Neurological Disease","Antibacterial; Endogenous Metabolite","Metabolism; Microbiology/virology","D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of the growth of E. coli. D-cysteine is mediated by D-amino acid oxidase to produce H2S, and is a neuroprotective agent against cerebellar ataxia. D-cysteine can inhibit the growth and cariogenicity of a two-species biofilm formed by Streptococcus mutans and Streptococcus hemoglobin.",121.16,"921-01-7",0,0,0,">10","https://www.selleckchem.com/products/d-cysteine.html","C3H7NO2S","Amino acid","D-Cysteine","NC(CS)C(O)=O",-3.078,1,1,2]
["E4002","Potassium D-gluconate","d5","L1300-40","in 10mM Water","PMDA,DMF,NDC","USP-NF2024;Martindale: The Complete Drug Reference",null,"Infection/Cancer","Fungal","Microbiology","Potassium D-gluconate(Potassium Gluconate) is an orally active carboxylic acid by the oxidation with antiseptic and chelating properties.",235.25,"299-27-4",2,8.5,47,199.79,"https://www.selleckchem.com/products/potassium-d-gluconate.html","C6H12O7.K","Salt","Potassium Gluconate","[K;v0].OCC(O)C(O)C(O)C(O)C(O)=O",-2.813,1,5,5]
["E4018","Ammonium sulfate","e5","L1300-40","in 10mM Water","NDC;FDA","BP2023;USP-NF2023;EP8.7",null,"dry, scaly skin (xerosis)","Others","Others","Ammonium sulphate (Mascagnite) is an inorganic sulfate salt used for the purification of enzymes and antibodies.",132.14,"7783-20-2","<1",0,23,174.06,"https://www.selleckchem.com/products/ammonium-sulfate.html","H3N.1/2H2O4S","Sulfate","Mascagnite","N.O[S](O)(=O)=O",-0.918,0,0,0]
["E2895","Sodium Bicarbonate","f5","L1300-40","in 10mM Water","FDA;NDC;PMDA;HMA;DMF","JP18;BP2023;USP-NF2023","018469;019011;018983;019797","heartburn, acid indigestion, and upset stomach as well as the treatment of metabolic acidosis associated with conditions such as severe renal disease and circulatory insufficiency due to shock","Others","Others","Sodium bicarbonate(Armex Blast Media Flow Formula XL, BI-CF 40E, BI-H 40E, Bakeshure 180, Sodium Hydrogen Carbonate, Sodium hydrogen carbonate) is a biochemical reagent used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.",85.01,"144-55-8","<1",0,25,294.08,"https://www.selleckchem.com/products/sodium-bicarbonate.html","CH2O3.Na","Bicarbonate","Armex Blast Media Flow Formula XL, BI-CF 40E, BI-H 40E, Bakeshure 180, Sodium Hydrogen Carbonate, Sodium hydrogen carbonate","[Na;v0].OC(O)=O",0.213,0,0,0]
["E4470","Potassium Chloride","g5","L1300-40","in 10mM Water","DMF; FDA; NDC; NMPA","USP42-NF37",null,"hypokalemia","Others","Others","Potassium chloride is an inorganic salt commonly used in fertilizer industry. It is also extensively used as a potassium supplement.",74.55,"7447-40-7","<1",0,100,1341.38,"https://www.selleckchem.com/products/potassium-chloride.html","ClK","Chloride",0,"Cl[K]",0.485,0,0,0]
["E4578","Trilaciclib dihydrochloride","a6","L1300-40","in 10mM Water","FDA,NDC,DMF",null,"214200","Cancer","CDK","Cell Cycle","Trilaciclib dihydrochloride(G1T28 dihydrochloride) is a potent inhibitor of <b>CDK4/cyclin D1</b> and <b>CDK6/cyclin D3</b> with IC50s of 1 nM and 4 nM for CDK4 and CDK6, respectively. Trilaciclib hydrochloride regulates cell proliferation and protects against chemotherapy toxicity in murine and canine bone marrow cells.",519.47,"1977495-97-8",1.3,2.5025507,25,48.125975,"https://www.selleckchem.com/products/trilaciclib-hydrochloride","C24H30N8O.2ClH","Free base","G1T28 dihydrochloride","[ClH:34].[CH3:3][N:33]1[CH2:31][CH2:29][N:28]([CH2:30][CH2:32]1)[C:27]2=[CH:25][CH:23]=[C:22]([NH:2][C:20]3=[N:21][CH:19]=[C:14]4[CH:16]=[C:10]5[N:5]([C:9]4=[N:15]3)[C:4]6([CH2:7][CH2:12][CH2:18][CH2:13][CH2:8]6)[CH2:6][NH:11][C:17]5=[O:1])[N:24]=[CH:26]2",3.743,4,2,3]
["S2542","Phenformin (NSC-756501) HCl","b6","L1300-40","in 10mM Water","DMF","Martindale:The Extra Pharmacopoeia",null,"Endocrinology/Metabolic Disease","AMPK","PI3K/Akt/mTOR","Phenformin HCl (NSC-756501, Phenethylbiguanide) is a hydrochloride salt of phenformin that is an anti-diabetic drug from the biguanide class. It activates AMPK, increasing activity and phosphorylation.",241.72,"834-28-6",0,0,0,">10","http://selleckchem.com/products/Phenformin-hydrochloride.html","C10H15N5.HCl","Hydrochloride","Phenethylbiguanide HCl","Cl.NC(=N)NC(=N)NCCC1=CC=CC=C1",1.339,0,3,6]
["S1023","Erlotinib (OSI-774) HCl","a2","L1300-41","in 2mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","091002,091059,208488","Cancer/Respiratory Disease","Autophagy,EGFR","Protein Tyrosine Kinase","Erlotinib (OSI-774, CP358774, NSC 718781) HCl is an EGFR inhibitor with IC50 of 2 nM in cell-free assays, >1000-fold more sensitive for EGFR than human c-Src or v-Abl.",429.9,"183319-69-9",4,9.3,"<1",0,"http://selleckchem.com/products/Erlotinib-Hydrochloride.html","C22H23N3O4.HCl","Hydrochloride","CP358774, NSC 718781,OSI-774 HCl","Cl.COCCOC1=C(OCCOC)C=C2C(=NC=NC2=C1)NC3=CC=CC(=C3)C#C",4.691,6,1,10]
["S1046","Vandetanib (ZD6474)","b2","L1300-41","in 2mM DMSO","FDA,EMA,NDC,PMDA",null,"022405","Cancer","Apoptosis related,Autophagy,EGFR,ROS,VEGFR","Protein Tyrosine Kinase","Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 with IC50 of 40 nM in a cell-free assay. It also inhibits VEGFR3 and EGFR with IC50 of 110 nM and 500 nM, respectively. Not sensitive to PDGFRβ, Flt1, Tie-2 and FGFR1 with IC50 of 1.1-3.6 μM. No activity against MEK, CDK2, c-Kit, erbB2, FAK, PDK1, Akt and IGF-1R with IC50 above 10 μM. Vandetanib (ZD6474) increases apoptosis and induces autophagy by increasing the level of reactive oxygen species (ROS).",475.35,"443913-73-3",4,8.41,"<1",0,"http://selleckchem.com/products/Vandetanib.html","C22H24BrFN4O2","free base","ZD6474","COC1=CC2=C(C=C1OCC3CCN(C)CC3)N=CN=C2NC4=C(F)C=C(Br)C=C4",5.087,4,1,6]
["S1211","Imiquimod (R-837)","c2","L1300-41","in 2mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","078548,078837,091044,091308,200173,200481,201994,202002,205971","Cancer/Infection","Immunology & Inflammation related","Immunology & Inflammation","Imiquimod (Aldara,R-837,S-26308) is a novel synthetic agent with immune response modifying activity.",240.3,"99011-02-6",1,4.16,"<1",0,"http://selleckchem.com/products/Imiquimod.html","C14H16N4","free base","Aldara,R-837, S-26308","CC(C)C[N]1C=NC2=C(N)N=C3C=CC=CC3=C12",2.722,2,1,2]
["S1288","Camptothecin (NSC-100880)","d2","L1300-41","in 2mM DMSO","DMF,CFDA",null,null,"Cancer","ADC Cytotoxin,Apoptosis related,MicroRNA,Topoisomerase","DNA Damage/DNA Repair","Camptothecin (NSC-100880, CPT, Campathecin, (S)-(+)-Camptothecin) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM in a cell-free assay. Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2.",348.35,"7689-03-4",3,8.61,"<1",0,"http://selleckchem.com/products/Camptothecine.html","C20H16N2O4","Free Base","CPT, Campathecin, (S)-(+)-Camptothecin","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC=CC5=C4)C2=O",1.746,4,0,1]
["S1353","Ketoconazole (R 41400)","e2","L1300-41","in 2mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,KP Ⅹ,EP9.2,Ph.Int_6th,JP17,BP2017,IP2010","074971,075273,075314,075319,075341,075362,075581,075597,075912,076294,076419,076942,091550,210457","Infection","Androgen Receptor,Fungal,P450 (e.g. CYP17)","Metabolism","Ketoconazole (R 41400) inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively. Ketoconazole is an androgen biosynthesis inhibitor.",531.43,"65277-42-1",5,9.41,"<1",0,"http://selleckchem.com/products/Ketoconazole.html","C26H28Cl2N4O4","free base","R 41400","CC(=O)N1CCN(CC1)C2=CC=C(OCC3COC(C[N]4C=CN=C4)(O3)C5=CC=C(Cl)C=C5Cl)C=C2",3.61,5,0,7]
["S1371","Cefoselis Sulfate","f2","L1300-41","in 2mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Infection","Antibiotics","Microbiology","Cefoselis (FK 037 Sulfate) is a widely used beta-lactam antibiotic.",620.64,"122841-12-7",3,4.83,5,8.06,"http://selleckchem.com/products/Cefoselis-sulfate.html","C19H22N8O6S2.H2SO4","Sulfate","FK 037 Sulfate","CO/N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)CN3C=CC(=N)N3CCO)C4=CSC(=N4)N.O[S](O)(=O)=O",-2.894,6,3,9]
["S1424","Prazosin HCl","g2","L1300-41","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8,JP17,BP2017,IP2010","071745,071994,071995,072333,072352,072573,072574,072575,072577,072609,072705,072706,072707,072782,072783,072784,072921,072991,072992,210971","Cardiovascular Disease/Neurological Disease","Adrenergic Receptor","GPCR & G Protein","Prazosin HCl (cp-12299-1) is a competitive alpha-1 adrenoceptor antagonist, used to treat high blood pressure or benign prostatic hyperplasia.",419.86,"19237-84-4",4,9.53,"<1",0,"http://selleckchem.com/products/Prazosin-hydrochloride.html","C19H21N5O4.HCl","Hydrochloride","cp-12299-1","Cl.COC1=CC2=C(C=C1OC)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N",2.489,6,1,4]
["S1463","Ofloxacin","h2","L1300-41","in 2mM DMSO","FDA,CFDA,DMF,PMDA","Martindale the Extra Pharmacopoei,CP2005,EP9.2,JP17,BP2017,USP39-NF34,IP2010","075762,076093,076128,076182,076220,076231,076407,076513,076527,076615,076616,076622,076830,076848,077098,078222,078559,090395,091656,202692","Infection","Topoisomerase","DNA Damage/DNA Repair","Ofloxacin (DL8280) is a synthetic broad-spectrum antimicrobial agent.",361.37,"82419-36-1",1,2.77,"<1",0,"http://www.selleck.cn/products/Ofloxacin(Floxin).html","C18H20FN3O4","Free Base","DL8280","CC1COC2=C(N3CCN(C)CC3)C(=CC4=C2N1C=C(C(O)=O)C4=O)F",-1.374,3,0,2]
["S1464","Marbofloxacin","a3","L1300-41","in 2mM DMSO",null,"USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Infection","Topoisomerase","DNA Damage/DNA Repair","Marbofloxacin is a potent antibiotic inhibiting bacterial DNA replication.",362.36,"115550-35-1",3,8.28,"<1",0,"http://selleckchem.com/products/Marbofloxacin.html","C17H19FN4O4","free base","N/A","CN1CCN(CC1)C2=C(F)C=C3C(=O)C(=CN4N(C)COC2=C34)C(O)=O",-2.038,3,0,2]
["S1507","Irbesartan","b3","L1300-41","in 2mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,JP17,BP2017","077159,077205,077466,079213,090201,090720,091236,200461,200832,201531,202254,202910,203020,203071,203081,203161,203534,203685,204740,204774,206194","Cardiovascular Disease","Angiotensin Receptor","GPCR & G Protein","Irbesartan (BMS-186295, SR-47436,APROVEL) is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM.",428.53,"138402-11-6",4,9.33,"<1",0,"http://selleckchem.com/products/Irbesartan(Avapro).html","C25H28N6O","free base","BMS-186295, SR-47436,APROVEL","CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=N[NH]N=N5",0,0,0,0]
["S1509","Norfloxacin","c3","L1300-41","in 2mM DMSO","FDA,DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.3,KP Ⅹ,JP17,BP2017,IP2010","019757,019384","Gastroenterology/Inflammation","Topoisomerase","DNA Damage/DNA Repair","Norfloxacin (MK-0366) is a broad-spectrum antibiotic. Norfloxacin (MK-0366) targets bacterial gyrase and topoisomerase IV enzymes.",319.33,"70458-96-7",3,9.39,"<1",0,"http://selleckchem.com/products/Norfloxacin(Norxacin).html","C16H18FN3O3","free base","MK-0366","CCN1C=C(C(O)=O)C(=O)C2=CC(=C(C=C12)N3CCNCC3)F",0,0,0,0]
["S1615","Risperidone","d3","L1300-41","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,JP17,BP2017","076228,076288,076440,076797,076879,076904,076908,076996,077328,077416,077493,077494,077542,077543,077719,077769,077784,077860,077953,078036,078040,078071,078116,078187,078269,078452,078464,078474,078516,078528,078707,078740,078744,078828,078871,078909,079059,079088,079158,090347,090839,091384,091537,201003,202386","Psychotic disorders","5-HT Receptor","Neuronal Signaling","Risperidone (R-64766) is a mutil-targeted antagonist for dopamine, serotonin, adrenergic and histamine receptors, used to treat schizophrenia and bipolar disorder.",410.48,"106266-06-2",4,9.74,"<1",0,"http://selleckchem.com/products/Risperidone(Risperdal).html","C23H27FN4O2","free base","R-64766","CC1=C(CCN2CCC(CC2)C3=NOC4=C3C=CC(=C4)F)C(=O)N5CCCCC5=N1",3.317,4,0,4]
["S1617","Sulfapyridine","e3","L1300-41","in 2mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","000159","Infection","Bacterial","Microbiology","Sulfapyridine  is a sulfonamide antibacterial.",249.29,"144-83-2",2,8.02,"<1",0,"http://selleckchem.com/products/Sulfapyridine(Dagenan).html","C11H11N3O2S","free base","N/A","NC1=CC=C(C=C1)[S](=O)(=O)NC2=NC=CC=C2",0.959,3,2,3]
["S1642","Methyldopa","f3","L1300-41","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,Ph.Int_6th,JP17,BP2017,IP2010","018934,070060,070070,070073,070074,070075,070076,070084,070085,070098,070192,070193,070194,070245,070246,070247,070260,070261,070262,070331,070332,070333,070343,070452,070535,070536,070537,070625,070669,070670,070703,070749,070750,071006,071009,071067,071105,071106,071700,071751,071752,071753,072126,072127,072128,","Cardiovascular Disease","5-HT Receptor,Adrenergic Receptor,Decarboxylase,Dopamine Receptor","Metabolism","Methyldopa (Aldomet) is a DOPA decarboxylase competitive inhibitor with an ED50 of 21.8 mg/kg.",211.21,"555-30-6",2,9.47,"<1",0,"http://selleckchem.com/products/Methyldopa(Aldomet).html","C10H13NO4","free base","N/A","CC(N)(CC1=CC(=C(O)C=C1)O)C(O)=O",0,0,0,0]
["S1698","Torsemide","g3","L1300-41","in 2mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37,KP Ⅹ","076110,076226,076346,076894,076943,078007,078249,078478,079234,090613,090656","Cardiovascular Disease/Metabolic Disease","Chloride Channel","Transmembrane Transporters","Torsemide (AC-4464, JDL-464) is a pyridyl sulfonylurea with a chemical structure between that of traditional loop diuretics and Cl- channel blockers, used to treat hypertension.",348.42,"56211-40-6",3,8.61,"<1",0,"http://selleckchem.com/products/Torsemide(Demadex).html","C16H20N4O3S","free base","AC-4464, JDL-464","CC(C)NC(=O)N[S](=O)(=O)C1=C(NC2=CC(=CC=C2)C)C=CN=C1",0,0,0,0]
["S1707","Eplerenone (CGP 30083)","h3","L1300-41","in 2mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.2,JP17,BP2017","078482,078510,203896,206922,208283","Cardiovascular Disease","Mineralocorticoid Receptor","Endocrinology & Hormones","Eplerenone (CGP 30083, SC-66110) is a mineralocorticoid receptor antagonist, and blocks the action of aldosterone, used to control high blood pressure.",414.49,"107724-20-9",4,9.65,"<1",0,"http://selleckchem.com/products/Eplerenone(Inspra).html","C24H30O6","free base","CGP 30083, SC-66110","COC(=O)C1CC2=CC(=O)CCC2(C)C34OC3CC5(C)C(CCC56CCC(=O)O6)C14",0,0,0,0]
["S1724","Paliperidone","a4","L1300-41","in 2mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","202645,203802,205618","Psychotic disorders","Dopamine Receptor","Neuronal Signaling","Paliperidone, the main active metabolite of Risperidone, is a potent serotonin-2A and dopamine-2 receptor antagonist, used in the treatment of schizophrenia.",426.48,"144598-75-4",4,9.38,"<1",0,"http://selleckchem.com/products/Paliperidone(Invega).html","C23H27FN4O3","free base","N/A","CC1=C(CCN2CCC(CC2)C3=NOC4=C3C=CC(=C4)F)C(=O)N5CCCC(O)C5=N1",0,0,0,0]
["S1837","Flubendazole","b4","L1300-41","in 2mM DMSO",null,"BP2019;KP Ⅹ;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","Autophagy,Parasite","Autophagy","Flubendazole (Flumoxanal, NSC 313680) is an autophagy inducer by targeting Atg4B, used to treat internal parasite and worm infection.",313.28,"31430-15-6",3,9.58,"<1",0,"http://selleckchem.com/products/flubendazole-flutelmium.html","C16H12FN3O3","free base","Flumoxanal, NSC 313680","COC(=O)NC1=NC2=C([NH]1)C=C(C=C2)C(=O)C3=CC=C(F)C=C3",3.26,4,2,4]
["S1851","Oxibendazole","c4","L1300-41","in 2mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Parasite","Parasite","Microbiology","Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets.",249.27,"20559-55-1",1,4.01,"<1",0,"http://selleckchem.com/products/oxibendazole.html","C12H15N3O3","Free Base","N/A","CCCOC1=CC=C2N=C(NC(=O)OC)[NH]C2=C1",2.506,4,2,5]
["S1929","Irsogladine","d4","L1300-41","in 2mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Gastroenterology","AChR,PDE","Metabolism","Irsogladine(Dicloguamine) is an anti-gastric ulcer agent that facilitates gap-junctional intercellular communication through M1 muscarininc acetylcholine receptor binding.",256.09,"57381-26-7",2,7.81,"<1",0,"http://selleckchem.com/products/Irsogladine-maleate.html","C9H7Cl2N5","free base","Dicloguamine","NC1=NC(=NC(=N1)C2=C(Cl)C=CC(=C2)Cl)N",2.443,3,2,1]
["S1977","Sarafloxacin HCl","e4","L1300-41","in 2mM DMSO",null,"BP2019;EP9.2;Martindale:The Extra Pharmacopoeia",null,"Infection","Antibiotics","Microbiology","Sarafloxacin HCl (A-56620) is a hydrochloride salt form of sarafloxacin which is a quinolone antibiotic drug with IC50 of 0.96 μg/L.",421.83,"91296-87-6",4,9.48,"<1",0,"http://selleckchem.com/products/sarafloxacin-hydrochloride.html","C20H17F2N3O3.HCl","Hydrochloride","A-56620 HCl","Cl.OC(=O)C1=CN(C2=CC=C(F)C=C2)C3=C(C=C(F)C(=C3)N4CCNCC4)C1=O",0,0,0,0]
["S1986","Meclizine 2HCl","f4","L1300-41","in 2mM DMSO","FDA,DMF,NDC","USP42-NF37,KP Ⅹ,IP2010","040179,040659,083784,084092,084382,084657,084843,084872,084975,084976,085195,085252,085253,085269,085523,085524,085740,085891,086392,087127,087128,087620,087877,088256,088257,088732,088733,088734,089113,089114,089674,200294,201451,202640,205136","Neurological Disease","CAR,Histamine Receptor","Neuronal Signaling","Meclizine (NSC 28728,Meclozine dihydrochloride) is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation properties, also an agonist ligand for mCAR (constitutive androstane receptor) and an inverse agonist for hCAR.",463.87,"1104-22-9",4,8.62,"<1",0,"http://selleckchem.com/products/meclizine-dihydrochloride.html","C25H27Cl2N2.2HCl","Dihydrochloride","NSC 28728,Meclozine dihydrochloride","Cl.Cl.CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(Cl)C=C4",0,0,0,0]
["S2035","Epalrestat (ONO-2235)","g4","L1300-41","in 2mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17",null,"Cancer","Aldose Reductase,Carbohydrate Metabolism","Metabolism","Epalrestat (ONO-2235) is an aldose reductase inhibitor with IC50 of 72 nM.",319.4,"82159-09-9",3,9.39,"<1",0,"http://selleckchem.com/products/epalrestat.html","C15H13NO3S2","free base","ONO-2235","CC(=C/C1=CC=CC=C1)\\C=C2/SC(=S)N(CC(O)=O)C2=O",3.442,2,0,4]
["S2047","Lornoxicam","h4","L1300-41","in 2mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia",null,"Immunology/Inflammation","COX","Neuronal Signaling","Lornoxicam (Chlortenoxicam) is a non-steroidal COX-1/COX-2 inhibitor, used as an anti-inflammatory drug to treat pain, osteoarthritis, and rheumatoid arthritis.",371.82,"70374-39-9",3,8.07,"<1",0,"http://selleckchem.com/products/lornoxicam-xefo.html","C13H10ClN3O4S2","free base","Chlortenoxicam","CN1C(=C(O)C2=C(C=C(Cl)S2)[S]1(=O)=O)C(=O)NC3=NC=CC=C3",0.913,4,2,2]
["S2110","Vinpocetine","a5","L1300-41","in 2mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017",null,"Angiology/Neurological Disease","Sodium Channel","Transmembrane Transporters","Vinpocetine (RGH-4405,Ethyl apovincaminate,AY 27255) is a selective inhibitor of voltage-sensitive sodium channel for the treatment of stroke, vascular dementia  and Alzheimer's disease.",350.45,"42971-09-5",3,8.56,"<1",0,"http://selleckchem.com/products/vinpocetine-cavinton.html","C22H26N2O2","free base","RGH-4405,Ethyl apovincaminate,AY 27255","CCOC(=O)C1=CC2(CC)CCCN3CCC4=C(C23)[N]1C5=CC=CC=C45",0,0,0,0]
["S2150","Neratinib (HKI-272)","b5","L1300-41","in 2mM DMSO","FDA,EMA,NDC",null,"208051","Cancer","EGFR,HER2","Protein Tyrosine Kinase","Neratinib (HKI-272) is a highly selective HER2 and EGFR inhibitor with IC50 of 59 nM and 92 nM in cell-free assays; weakly inhibits KDR and Src, no significant inhibition to Akt, CDK1/2/4, IKK-2, MK-2, PDK1, c-Raf and c-Met. Phase 3.",557.04,"698387-09-6",5,8.98,"<1",0,"http://selleckchem.com/products/Neratinib(HKI-272).html","C30H29ClN6O3","free base","N/A","CCOC1=C(NC(=O)\\C=C\\CN(C)C)C=C2C(=C1)N=CC(=C2NC3=CC=C(OCC4=NC=CC=C4)C(=C3)Cl)C#N",4.881,5,2,11]
["S2152","Sitafloxacin Hydrate","c5","L1300-41","in 2mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia",null,"Infection/Inflammation","Antibiotics","Microbiology","Sitafloxacin Hydrate (DU-6859a) is a new-generation, broad-spectrum oral fluoroquinolone antibiotic.",436.84,"163253-35-8",4,9.16,"<1",0,"http://selleckchem.com/products/Sitafloxacin(DU-6859A).html","C19H18ClF2N3O3.3/2H2O","1.5 hydrate","DU-6859a","O.O.O.NC1CN(CC12CC2)C3=C(Cl)C4=C(C=C3F)C(=O)C(=CN4C5CC5F)C(O)=O.NC6CN(CC67CC7)C8=C(Cl)C9=C(C=C8F)C(=O)C(=CN9C%10CC%10F)C(O)=O",0.344,2,1,3]
["S2206","Fostamatinib (R788) disodium","d5","L1300-41","in 2mM DMSO","FDA",null,"209299","Hematology/Immunology","Syk","Angiogenesis","Fostamatinib disodium  (R788, Tamatinib Fosdium), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.",624.42,"1025687-58-4",6,9.61,"<1",0,"http://selleckchem.com/products/R788(Fostamatinib-disodium).html","C23H24FN6O9P.2Na","Sodium Salt","Tamatinib Fosdium","[Na+].[Na+].COC1=C(OC)C(=CC(=C1)NC2=NC=C(F)C(=N2)NC3=CC=C4OC(C)(C)C(=O)N(CO[P]([O-])([O-])=O)C4=N3)OC",0,0,0,0]
["S2232","Ketanserin","e5","L1300-41","in 2mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","5-HT Receptor","Neuronal Signaling","Ketanserin (R41468, Ketanserinum) is a specific 5-HT2A serotonin receptor antagonist with Ki of 2.5 nM for rat and human 5-HT2A, used as an antihypertensive drug.",395.43,"74050-98-9",2,5.06,"<1",0,"http://selleckchem.com/products/Ketanserin-Vulketan-Gel.html","C22H22FN3O3","Free Base","R41468, Ketanserinum","FC1=CC=C(C=C1)C(=O)C2CCN(CC2)CCN3C(=O)NC4=CC=CC=C4C3=O",2.991,3,1,5]
["S2251","(-)-Huperzine A (HupA)","f5","L1300-41","in 2mM DMSO","DMF","CP2005",null,"Neurological Disease","AChR,GluR","Neuronal Signaling","(-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4.",242.32,"102518-79-6",0.66,2.72,"<1",0,"http://selleckchem.com/products/(-)-Huperzine-A.html","C15H18N2O","Free Base","N/A","C\\C=C/1C2CC3=C(C=CC(=O)N3)C1(N)CC(=C2)C",1.056,1,2,0]
["S2292","Diosmin","g5","L1300-41","in 2mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,BP2017",null,"Angiology","AhR","Metabolism","Diosmin is an agonist of the aryl hydrocarbon receptor (AhR). Diosmin is a semisynthetic phlebotropic agent and a flavonoid found in a variety of citrus fruits.",608.55,"520-27-4",6,9.86,"<1",0,"http://selleckchem.com/products/Diosmin.html","C28H32O15","Free Base","N/A","COC1=C(O)C=C(C=C1)C2=CC(=O)C3=C(O2)C=C(OC4OC(COC5OC(C)C(O)C(O)C5O)C(O)C(O)C4O)C=C3O",-0.395,7,8,7]
["S2424","Hypoxanthine","h5","L1300-41","in 2mM DMSO","DMF","USP42-NF37,EP9.2,BP2017",null,"Infection","Others","Others","Hypoxanthine, a naturally occurring purine derivative, an intermediate product of uric acid synthesis, formed from adenylic acid and itself a precursor of xanthine.",136.11,"68-94-0",0.4,2.94,"<1",0,"http://selleckchem.com/products/hypoxanthine.html","C5H4N4O","Free Base","N/A","O=C1NC=NC2=C1[NH]C=N2",-0.532,3,2,0]
["S2476","Itraconazole (R 51211)","a6","L1300-41","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,JP17,BP2017","076104,200463,203445,204672,205080,205573,205724,205991,206741,208591,209460","Infection","Autophagy,Fungal,Hedgehog/Smoothened,P450 (e.g. CYP17)","Stem Cells & Wnt","Itraconazole (R 51211) is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy.",705.65,"84625-61-6",7,9.92,"<1",0,"http://selleckchem.com/products/Itraconazole(Sporanox).html","C35H38Cl2N8O4","free base","R 51211","CCC(C)N1N=CN(C1=O)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(OCC5COC(C[N]6C=NC=N6)(O5)C7=CC=C(Cl)C=C7Cl)C=C4",6.434,7,0,11]
["S2530","7-Aminocephalosporanic acid","b6","L1300-41","in 2mM DMSO","DMF",null,null,"Others","Antibiotics","Microbiology","7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates.",272.28,"957-68-6",1,3.67,"<1",0,"http://selleckchem.com/products/7-Aminocephalosporanic-acid.html","C10H12N2O5S","Free Base","N/A","CC(=O)OCC1=C(N2C(SC1)C(N)C2=O)C(O)=O",-3.745,4,1,4]
["S2582","Trazodone HCl","c6","L1300-41","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017","070491,070492,070857,070858,070921,071112,071113,071139,071140,071196,071258,071405,071406,071514,071523,071524,071525,071636,072192,072193,072483,072484,073137,074357,090514,202180,205253,206923","Psychotic disorders","5-HT Receptor","Neuronal Signaling","Trazodone HCl (AF-1161, KB-831) is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.",408.32,"25332-39-2",4,9.8,"<1",0,"http://selleckchem.com/products/trazodone-hydrochloride-desyrel.html","C19H22ClN5O.HCl","Hydrochloride","AF-1161, KB-831","Cl.ClC1=CC(=CC=C1)N2CCN(CCCN3N=C4C=CC=CN4C3=O)CC2",0,0,0,0]
["S2597","Oseltamivir Phosphate","d6","L1300-41","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,Ph.Int_6th,BP2017,IP2010","202595,207211,208347,208348,208578,208823,209093,209113,209421,209438,210186,211125","Infection","Influenza Virus,Neuraminidase","Microbiology","Oseltamivir Phosphate(Tamiflu) is a potent and selective inhibitor of the neuraminidase that is essential for replication of influenza A and B viruses, used to prevent influenza.",410.4,"204255-11-8",4,9.75,"<1",0,"http://selleckchem.com/products/oseltamivir-phosphate-Tamiflu.html","C16H28N2O4.H3PO4","Phosphate salt","Tamiflu","CCOC(=O)C1=CC(OC(CC)CC)C(NC(C)=O)C(N)C1.O[P](O)(O)=O",0.577,4,2,8]
["S2788","Capmatinib (INCB28060)","e6","L1300-41","in 2mM DMSO","FDA, NDC, PMDA",null,213591,"Cancer","Apoptosis related,c-Met,Wnt/beta-catenin","Protein Tyrosine Kinase","Capmatinib (INCB28060, INC280, NVP-INC280) is a novel, ATP-competitive inhibitor of c-MET with IC50 of 0.13 nM in a cell-free assay, inactive against RONβ, as well as EGFR and HER-3. Capmatinib (INCB28060) inhibits Wnt/β-catenin and EMT signaling pathways and induces apoptosis in diffuse gastric cancer positive for c-MET amplification. Phase 1.",412.42,"1029712-80-8",2,4.85,"<1",0,"http://selleckchem.com/products/incb28060.html","C23H17FN6O","Free Base","INC280, NVP-INC280","CNC(=O)C1=CC=C(C=C1F)C2=N[N]3C(=CN=C3N=C2)CC4=CC=C5N=CC=CC5=C4",3.246,5,1,4]
["S2920","Mozavaptan","f6","L1300-41","in 2mM DMSO","marketed in Japan","Martindale:The Extra Pharmacopoeia",null,"Endocrinology","Vasopressin Receptor","GPCR & G Protein","Mozavaptan (OPC-31260) is a novel competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM, respectively.",427.54,"137975-06-5",1,2.34,"<1",0,"http://selleckchem.com/products/mozavaptan.html","C27H29N3O2","Free Base","OPC-31260","CN(C)C1CCCN(C(=O)C2=CC=C(NC(=O)C3=C(C)C=CC=C3)C=C2)C4=C1C=CC=C4",4.654,2,1,4]
["S3041","Droxidopa","g6","L1300-41","in 2mM DMSO","FDA,CFDA,DMF,NDC,PMDA","Martindale the Extra Pharmacopoei,JP17",203202,"Neurological Disease","Adrenergic Receptor","GPCR & G Protein","Droxidopa (L-DOPS) is a psychoactive drug and acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline).",213.19,"23651-95-8",2,9.38,1,4.69,"http://www.selleck.cn/products/droxidopa-l-dops.html","C9H11NO5","Free Base","L-DOPS","NC(C(O)C1=CC(=C(O)C=C1)O)C(O)=O",-2.921,1,4,3]
["S3059","Enrofloxacin","h6","L1300-41","in 2mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017",null,"Infection","Antibiotics","Microbiology","Enrofloxacin (BAY-Vp2674, PD160788) is a fluoroquinolone antibiotic.",359.39,"93106-60-6",3,8.35,"<1",0,"http://selleckchem.com/products/enrofloxacin.html","C19H22FN3O3","free base","BAY-Vp2674, PD160788","CCN1CCN(CC1)C2=CC3=C(C=C2F)C(=O)C(=CN3C4CC4)C(O)=O",0,0,0,0]
["S3064","Ambroxol HCl","a7","L1300-41","in 2mM DMSO","CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,EP9.2,EP9.1,BP2017,IP2010",null,"Respiratory Disease","Sodium Channel","Transmembrane Transporters","AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. Phase 3.",414.56,"23828-92-4",4,9.65,"<1",0,"http://selleckchem.com/products/ambroxol-hcl.html","C13H18Br2N2O.HCl","Hydrochloride","N/A","Cl.NC1=C(Br)C=C(Br)C=C1CNC2CCC(O)CC2",3.121,0,3,3]
["S3636","Cefadroxil hydrate","b7","L1300-41","in 2mM DMSO","FDA,DMF,CFDA,NDC,HMA","KP Ⅹ,EP9.2,BP2017","062291,062334,062695,062698,062766,062774,063017,065015,065018,065115,065260,065278,065282,065301,065307,065309,065311,065349,065352,065392,065396,091036,205072","Infection","Antibiotics,Bacterial","Microbiology","Cefadroxil(BL-S 578 hydrate) is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.",381.4,"66592-87-8",1.76,4.61,0,0,"http://selleckchem.com/products/cefadroxil-hydrate.html","C16H17N3O5S.H2O","hydrate","BL-S 578 hydrate","O.CC1=C(N2C(SC1)C(NC(=O)C(N)C3=CC=C(O)C=C3)C2=O)C(O)=O",-2.704,3,3,4]
["S3721","Bilastine","c7","L1300-41","in 2mM DMSO","DMF,PMDA,HMA",null,null,"Immunology","Histamine Receptor","Neuronal Signaling","Bilastine is a new, well-tolerated, nonsedating H1 receptor antihistamine and has a rapid onset and prolonged duration of action.",463.61,"202189-78-4",1,2.16,"<1",0,"http://selleckchem.com/products/bilastine.html","C28H37N3O3","free base","N/A","CCOCC[N]1C(=NC2=C1C=CC=C2)C3CCN(CC3)CCC4=CC=C(C=C4)C(C)(C)C(O)=O",2.07,3,0,10]
["S3770","Sodium Aescinate","d7","L1300-41","in 2mM DMSO","CFDA","CP2005",null,"Cancer/Inflammation","NF-κB","NF-κB","Sodium Aescinate (SA, Escin Sodium Salt) is a widely-applied triterpene saponin product derived from horse chestnut seeds, possessing vasoactive and organ-protective activities with oral or injection administration in the clinic.  Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway.",1123.21,"20977-05-3",10,8.9,0,0,"http://selleckchem.com/products/sodium-aescinate.html","C54H83NaO23","sodium salt","Escin sodium salt","CC(OC(C)=O)C(C)C(=O)OCC12C(O)C3OC1CC4(C)C(=CCC5C6(C)CCC(OC7OC(C(OC8OC(CO)C(O)C(O)C8O)C(O)C7OC9OCC(O)C(O)C9O)C(=O)O[Na])C(C)(CO)C6CCC45C)C2CC3(C)C",-0.485,13,10,17]
["S3801","Sodium Houttuyfonate","e7","L1300-41","in 2mM DMSO","CFDA",null,null,"Inflammation","Anti-infection","Microbiology","Sodium Houttuyfonate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.",330.42,"1847-58-1",2,6.05,"<1",0,"http://selleckchem.com/products/sodium-houttuyfonate.html","C14H27O5S.Na","sodium salt","N/A","[Na+].CCCCCCCCCCCCOC(=O)C[S]([O-])(=O)=O",2.026,2,0,14]
["S3821","Nuciferine","f7","L1300-41","in 2mM DMSO",null,"CP2005",null,"Infection/Inflammation","5-HT Receptor,5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Nuciferine (Sanjoinine E, (-)-Nuciferine, VLT 049) is a major active aporphine alkaloid from the leaves of N. nucifera Gaertn and possesses anti-hyperlipidemia, anti-hypotensive, anti-arrhythmic, and insulin secretagogue activities. Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 μM) and 5-HT6 (EC50=700 nM), an agonist at 5-HT1A (EC50=3.2 μM) and D4 (EC50=2 μM) receptor.",295.38,"475-83-2",2,6.77,"<1",0,"http://selleckchem.com/products/nuciferine.html","C19H21NO2","free base","Sanjoinine E, (-)-Nuciferine, VLT 049","COC1=C(OC)C2=C3C(CC4=C2C=CC=C4)N(C)CCC3=C1",3.567,2,0,2]
["S3891","Vincamine","g7","L1300-41","in 2mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Angiology","Others","Others","Vincamine (Angiopac, Devincan, Equipur, Minorin, Novicet, Oxybral, Perval, Sostenil, Tripervan), an indole alkaloid found in the leaves of V. minor and C. roseus, is a peripheral vasodilator that increases blood flow to the brain.",354.44,"1617-90-9",3,8.46,0,0,"http://selleckchem.com/products/vincamine.html","C21H26N2O3","free base","Angiopac, Devincan, Equipur, Minorin, Novicet, Oxybral, Perval, Sostenil, Tripervan","CCC12CCCN3CCC4=C(C13)[N](C5=CC=CC=C45)C(O)(C2)C(=O)OC",3.546,2,0,3]
["S4033","Sennoside A","h7","L1300-41","in 2mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Infection","MAO","Metabolism","Sennoside A (NSC 112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.",862.74,"81-27-6",0,2,"<1",0,"http://selleckchem.com/products/sennoside-a.html","C42H38O20","Free Base","NSC 112929","OCC1OC(OC2=CC=CC3=C2C(=O)C4=C(O)C=C(C=C4C3C5C6=C(C(=O)C7=C(O)C=C(C=C57)C(O)=O)C(=CC=C6)OC8OC(CO)C(O)C(O)C8O)C(O)=O)C(O)C(O)C1O",0.409,8,10,9]
["S4126","Retinyl (Vitamin A) Palmitate","a8","L1300-41","in 2mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37","080819,083311,083321,083948,083981","Ophthalmology","Vitamin","Metabolism","Retinyl (Vitamin A) Palmitate is a more stable, synthetic version of the essential nutrient vitamin A joined to palmitic acid.",524.86,"79-81-2",3,5.72,"<1",0,"http://selleckchem.com/products/vitamin-a-palmitate.html","C36H60O2","Free Base","Vitamin A palmitate","CCCCCCCCCCCCCCCC(=O)OC/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C",12.293,2,0,21]
["S4142","Clopidol","b8","L1300-41","in 2mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Parasite","Anti-infection","Microbiology","Clopidol (WR 61112) is an antiprotozoal agent.",192.04,"2971-90-6",1,5.21,"<1",0,"http://selleckchem.com/products/clopidol.html","C7H7Cl2NO","free base","WR 61112","CC1=C(Cl)C(=C(Cl)C(=N1)C)O",2.331,1,1,0]
["S4156","Chlortetracycline HCl (NSC 13252)","c8","L1300-41","in 2mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,Ph.Int_5th","050404","Infection","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics","Microbiology","Chlortetracycline HCl (NSC 13252, 7-Chlorotetracycline, Aureomycin monohydrochloride) is the first identified tetracycline antibiotic.",515.34,"64-72-2",5,9.7,1,1.94,"http://selleckchem.com/products/chlortetracycline-hcl.html","C22H23ClN2O8.HCl","Hydrochloride","7-Chlorotetracycline HCl, Aureomycin monohydrochloride","Cl.CN(C)C1C2CC3C(=C(O)C2(O)C(=O)C(=C1O)C(N)=O)C(=O)C4=C(C(=CC=C4O)Cl)C3(C)O",0,0,0,0]
["S4218","Amoxapine","d8","L1300-41","in 2mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,JP17","072418,072419,072420,072421,072691,072878,072879,072943,072944","Psychotic disorders","Amino acid transporter,GlyT","Neuronal Signaling","Amoxapine (CL 67772,Asendin) is a tricyclic dibenzoxazepine (an N-aryl piperazine) which acts similarly to several other tricyclic antidepressants, amoxapine inhibits GLYT2a transport activity with IC50 of 92 μM.",313.78,"14028-44-5",3,9.56,"<1",0,"http://selleckchem.com/products/amoxapine.html","C17H16ClN3O","free base","CL 67772,Asendin","ClC1=CC2=C(OC3=C(C=CC=C3)N=C2N4CCNCC4)C=C1",0,0,0,0]
["S4262","Ebastine","e8","L1300-41","in 2mM DMSO","CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.6,KP Ⅹ,JP17,BP2017",null,"Immunology","Histamine Receptor","Neuronal Signaling","Ebastine(LAS-W 090,RP64305) is a potent H1-histamine receptor antagonist, used for allergic disorders.",469.66,"90729-43-4",4,8.52,"<1",0,"http://selleckchem.com/products/ebastine.html","C32H39NO2","free base","LAS-W 090,RP64305","CC(C)(C)C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)OC(C3=CC=CC=C3)C4=CC=CC=C4",6.582,2,0,10]
["S4605","Folic acid","f8","L1300-41","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th.JP17,BP2017,IP2010","006135,040514,040582,040625,040756,040796,080600,080680,080686,080691,080755,080784,080816,080903,081066,083000,083133,083141,083526,083598,084158,084472,084915,085061,085141,086296,087828,088199,088730,088949,089177,089202,090035,091145,202437,204418,211064","Hematology","Vitamin","Metabolism","Folic acid (Folacin, Vitamin B9, Vitamin M, Pteroylglutamic acid, Folate), a B vitamin, plays an important role in cell division and in the synthesis of amino acids and nucleic acids like DNA.",441.4,"59-30-3",2,4.53,"<1",0,"http://selleckchem.com/products/folic-acid.html","C19H19N7O6","free base","Folacin, Vitamin B9, Vitamin M, Pteroylglutamic acid, Folate","NC1=NC(=O)C2=C(N1)N=CC(=N2)CNC3=CC=C(C=C3)C(=O)NC(CCC(O)=O)C(O)=O",-0.232,7,4,9]
["S4642","Dolutegravir Sodium","g8","L1300-41","in 2mM DMSO","FDA,DMF,EMA,NDC,PMDA",null,204790,"Infection","Integrase","Microbiology","Dolutegravir Sodium (GSK-1349572A) is a HIV integrase inhibitor with IC50 of 2.7 nM.",441.36,"1051375-19-9",2,4.53,"<1",0,"http://www.selleck.cn/products/dolutegravir-sodium.html","C20H19F2N3O5.Na","Sodium","GSK-1349572A","CC1CCOC2CN3C=C(C(=O)NCC4=C(F)C=C(F)C=C4)C(=O)C(=C3C(=O)N12)O[Na]",0.391,5,1,4]
["S4654","Netupitant","h8","L1300-41","in 2mM DMSO","FDA,DMF,NDC,HMA",null,"205718","Gastroenterology","Neurokinin Receptor","Neuronal Signaling","Netupitant (CID6451149) is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity.",578.59,"290297-26-6",2,3.46,"<1",0,"http://selleckchem.com/products/netupitant.html","C30H32F6N4O","Free Base","CID6451149, CID 6451149, CID-6451149","CN1CCN(CC1)C2=CC(=C(C=N2)N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C4=CC=CC=C4C",7.132,2,0,7]
["S4930","Cetilistat","a9","L1300-41","in 2mM DMSO","PMDA",null,null,"Metabolic Disease","Lipase","Metabolism","Cetilistat (ATL962) is a novel highly lipophilic benzoxazinone that inhibits gastrointestinal and pancreatic lipases. It shows a good safety and tolerability profile in vivo",401.58,"282526-98-1",3,7.47,"<1",0,"http://selleckchem.com/products/cetilistat.html","C25H39NO3","free base","ATL962","CCCCCCCCCCCCCCCCOC1=NC2=C(C=C(C)C=C2)C(=O)O1",9.409,4,0,16]
["S5018","Mebhydrolin napadisylate","b9","L1300-41","in 2mM DMSO","marketed in Bangladesh and Russia",null,null,"Immunology","ADC Cytotoxin,Histamine Receptor","Neuronal Signaling","Mebhydrolin Napadisylate (Diazoline, Diazolin, Incidal, Omeril) is classified as an antihistamine drug classes used to treat allergies.",841.05,"6153-33-9",8,9.51,0,0,"http://selleckchem.com/products/mebhydrolin-napadisylate.html","C48H48N4O6S2","salt","Diazoline, Diazolin, Incidal, Omeril","CN1CCC2=C(C1)C3=C(C=CC=C3)[N]2CC4=CC=CC=C4.CN5CCC6=C(C5)C7=C(C=CC=C7)[N]6CC8=CC=CC=C8.O[S](=O)(=O)C9=C%10C=CC=C(C%10=CC=C9)[S](O)(=O)=O",9.536,0,0,6]
["S5035","6-Aminopenicillanic acid","c9","L1300-41","in 2mM DMSO","DMF","BP2019,EP9.1,USP32-NF27",null,"Others","Antibiotics","Microbiology","6-Aminopenicillanic acid (6-APA) is the central component of penicillin β-lactam antibiotics which are generated by Penicillium. It is used as precursor for antibiotic compounds ampicillin and amoxicillin.",216.26,"551-16-6",1,4.62,"<1",0,"http://selleckchem.com/products/6-aminopenicillanic-acid.html","C8H12N2O3S","free base","N/A","CC1(C)SC2C(N)C(=O)N2C1C(O)=O",-3.076,2,1,1]
["S5232","Alectinib (CH5424802) hydrochloride","d9","L1300-41","in 2mM DMSO","FDA,DMF,NDC",null,"208434","Cancer/Respiratory Disease","ALK","Protein Tyrosine Kinase","Alectinib (AF802, CH5424802, RO5424802, RG-7853) is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase.",519.08,"1256589-74-8",2,3.85,"<1",0,"http://selleckchem.com/products/alectinib-hydrochloride.html","C30H34N4O2.HCl","hydrochloride","AF802, RO5424802, RG-7853","Cl.CCC1=C(C=C2C(=C1)C(=O)C3=C([NH]C4=C3C=CC(=C4)C#N)C2(C)C)N5CCC(CC5)N6CCOCC6",5.585,2,1,3]
["S5272","Toceranib phosphate","e9","L1300-41","in 2mM DMSO","EMA",null,null,"Cancer","PDGFR,VEGFR","Protein Tyrosine Kinase","Toceranib phosphate (Palladia, SU11654), the phosphate salt of toceranib, is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family, including Flk-1/KDR, PDGFR, and Kit with Ki values of 6 nM and 5 nM for Flk-1/KDR and PDGFRβ, respectively.",494.45,"874819-74-6",2,4.04,2,4.04,"https://www.selleckchem.com/products/toceranib-phosphate.html","C22H25FN4O2.H3O4P","phosphate","Palladia, SU11654","CC1=C(C(=C([NH]1)\\C=C2/C(=O)NC3=C2C=C(F)C=C3)C)C(=O)NCCN4CCCC4.O[P](O)(O)=O",2.292,2,3,5]
["S5499","Amantadine","f9","L1300-41","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2016,IP2010","070589,071293,071382,072655,073115,074028,074170,074509,075060,075819,076186,076352,077659,077992,078720,207570,207571,208096,208107,208278,208966,209035,209047,209171,209221,210403","Infection/Neurological Disease","Influenza Virus","Microbiology","Amantadine (1-Adamantanamine, 1-Adamantylamine, 1-Aminoadamantane) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is an M2 inhibitor which blocks the ion channel formed by the M2 protein that spans the viral membrane.",151.25,"768-94-5",1,6.61,0,0,"http://selleckchem.com/products/amantadine.html","C10H17N","free base","1-Adamantanamine, 1-Adamantylamine, 1-Aminoadamantane","N[C]12C[CH]3[CH2]C([CH2][CH](C3)C1)C2",1.495,0,1,0]
["S5601","Balofloxacin Dihydrate","g9","L1300-41","in 2mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia",null,"Inflammation","Antibiotics","Microbiology","Balofloxacin Dihydrate is an orally active fluoroquinolone antibiotic.",425.45,"151060-21-8",2,4.7,"<1",0,"https://www.selleckchem.com/products/balofloxacin-dihydrate.html","C20H28FN3O6","free base","Neuroquinoron","O.O.CNC1CCCN(C1)C2=C(F)C=C3C(=O)C(=CN(C4CC4)C3=C2OC)C(O)=O",-1.029,3,1,5]
["S5677","Xanthopterin Hydrate","h9","L1300-41","in 2mM DMSO",null,"Martindale:The Extra Pharmacopoeia",null,"Others","Others","Others","Xanthopterin, isolated from butterfly wings and found in many other sources, replace folic acid in the nutrition of many animal species.",197.15,"5979-01-1",1,5.07,-1,0,"http://www.selleckchem.com/products/xanthopterin-hydrate.html","C6H7N5O3","Hydrate","N/A","O.NC1=NC(=C2N=C(O)C=NC2=N1)O",-0.128,4,3,0]
["S5712","Zofenopril calcium","a10","L1300-41","in 2mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia",null,"Cardiovascular Disease","RAAS","Endocrinology & Hormones","Zofenopril calcium (SQ-26991) is an angiotensin-converting enzyme (ACE) inhibitor that protects the heart and helps reduce high blood pressure.",897.17,"81938-43-4",0,2,"<1",0,"http://selleckchem.com/products/zofenopril-calcium.html","C44H44CaN2O8S4","calcium salt","SQ-26991","CC(CSC(=O)C1=CC=CC=C1)C(=O)N2CC(CC2C(=O)O[Ca]OC(=O)C3CC(CN3C(=O)C(C)CSC(=O)C4=CC=CC=C4)SC5=CC=CC=C5)SC6=CC=CC=C6",8.055,8,0,20]
["S5908","Garenoxacin","b10","L1300-41","in 2mM DMSO","DMF,marketed in Japan","Martindale:The Extra Pharmacopoeia",null,"Infection","Anti-infection","Microbiology","Garenoxacin (T-3811ME, BMS-284756) is a novel des-F(6) quinolone that has been shown to be effective in vitro against a wide range of clinically important pathogens, including gram-positive and gram-negative aerobes and anaerobes.",426.41,"194804-75-6",2,4.69,"<1",0,"http://www.selleckchem.com/products/garenoxacin.html","C23H20F2N2O4","Free Base","T-3811ME, BMS-284756","CC1NCC2=C1C=CC(=C2)C3=C(OC(F)F)C4=C(C=C3)C(=O)C(=CN4C5CC5)C(O)=O",0.934,3,1,5]
["S6632","Mirogabalin (DS-5565)","c10","L1300-41","in 2mM DMSO","PMDA",null,null,"Others","Others","Others","Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand that has been used in trials studying the treatment of Post-herpetic Neuralgia, Pain Associated With Fibromyalgia, and Diabetic peripheral neuropathic pain.",209.28,"1138245-13-2",2,9.56,3,14.33,"http://www.selleck.cn/products/mirogabalin-ds-5565.html","C12H19NO2","Free Base","N/A","CCC1=CC2C(C1)CC2(CN)CC(O)=O",-1.352,1,1,4]
["S7128","Tazemetostat (EPZ-6438)","d10","L1300-41","in 2mM DMSO","FDA, NDC",null,213400,"Cancer","EZH1/2,Histone Methyltransferase","Epigenetics","Tazemetostat (EPZ-6438, E7438) is a potent, and selective EZH2 inhibitor with Ki and IC50 of 2.5 nM and 11 nM in cell-free assays, exhibiting a 35-fold selectivity versus EZH1 and >4,500-fold selectivity relative to 14 other HMTs.",572.74,"1403254-99-8",5,8.73,"<1",0,"http://selleckchem.com/products/epz-6438.html","C34H44N4O4","free base","E7438","CCN(C1CCOCC1)C2=C(C)C(=CC(=C2)C3=CC=C(CN4CCOCC4)C=C3)C(=O)NCC5=C(C)C=C(C)NC5=O",3.506,4,2,9]
["S7756","Indoximod (NLG-8189）","e10","L1300-41","in 2mM DMSO","DMF",null,null,"Others","IDO/TDO","Metabolism","Indoximod (NLG-8189, 1-Methyl-D-tryptophan, 1-MT), a methylated tryptophan, acts as an IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor, and reverses IDO-mediated immune suppression. Phase 2.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!",218.25,"110117-83-4",1,4.58,"<1",0,"http://selleckchem.com/products/indoximod-nlg-8189.html","C12H14N2O2","Free Base","1-Methyl-D-tryptophan, 1-MT","C[N]1C=C(CC(N)C(O)=O)C2=CC=CC=C12",-1.106,1,1,3]
["S8229","Brigatinib (AP26113)","f10","L1300-41","in 2mM DMSO","FDA,EMA,NDC",null,208772,"Cancer","ALK,EGFR,FLT3,IGF-1R,ROS1","Angiogenesis","Brigatinib (AP26113) is a potent and selective ALK (IC50, 0.6 nM) and ROS1 (IC50, 0.9 nM) inhibitor. It also inhibits IGF-1R, FLT3, and mutant variants of FLT3 (D835Y) and EGFR with lower potentcy.",584.09,"1197953-54-0",3,5.14,"<1",0,"http://www.selleck.cn/products/brigatinib-ap26113.html","C29H39ClN7O2P","Free Base","N/A","COC1=C(NC2=NC(=C(Cl)C=N2)NC3=CC=CC=C3[P](C)(C)=O)C=CC(=C1)N4CCC(CC4)N5CCN(C)CC5",5.084,6,2,8]
["S8724","Lazertinib","g10","L1300-41","in 2mM DMSO","EMA,FDA,CFDA",null,"006074,219008","Cancer","EGFR","Protein Tyrosine Kinase","Lazertinib (YH25448,GNS-1480) is a potent, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively, showing much higher IC50 values aganist ErbB2 and ErbB4.",554.64,"1903008-80-9",4,7.21,"<1",0,"http://selleckchem.com/products/lazertinib-yh25448-gns-1480.html","C30H34N8O3","free base","YH25448,GNS-1480","COC1=CC(=C(NC(=O)C=C)C=C1NC2=NC=CC(=N2)[N]3C=C(CN(C)C)C(=N3)C4=CC=CC=C4)N5CCOCC5",4.56,6,2,10]
["S5098","Gefitinib hydrochloride","h10","L1300-41","in 2mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,EP9.3,EP9.2,BP2017,IP2010","021399,206995","Cancer/Respiratory Disease","EGFR","Protein Tyrosine Kinase","Gefitinib (ZD1839) is an EGFR inhibitor with IC50s of 15.5 nM and 823.3 nM for WT EGFR and EGFR (858R/T790M), respectively.",483.36,"184475-55-6",0,2,1,2.07,"http://selleckchem.com/products/gefitinib-hydrochloride.html","C22H24ClFN4O3.HCl","hydrochloride","ZD1839 hydrochloride","Cl.COC1=CC2=C(C=C1OCCCN3CCOCC3)C(=NC=N2)NC4=CC(=C(F)C=C4)Cl",4.585,5,1,8]
["S5031","Sulfaquinoxaline sodium","a11","L1300-41","in 2mM DMSO","DMF","Martindale:The Extra Pharmacopoeia",null,"Parasite","Parasite","Microbiology","Sulfaquinoxaline sodium (N'1-quinoxalin-2-ylsulphanilamide sodium, SQ-Na) is the sodium salt of sulfaquinoxaline, which is often used as a drug to prevent coccidiosis in poultry, swine, and sheep by inhibiting the synthesis of nucleic acids and proteins in microorganisms.",322.32,"967-80-6",0,2,0,0,"http://selleckchem.com/products/sulfaquinoxaline-sodium.html","C14H11N4O2S.Na","sodium salt","SQ-Na","NC1=CC=C(C=C1)[S](=O)(=O)N([Na])C2=CN=C3C=CC=CC3=N2",1.677,4,1,3]
["S1502","Cephalexin","b11","L1300-41","in 2mM DMSO","FDA,NDC,DMF","USP42-NF37,IP2010","061969,062117,062118,062702,062703,062713,062760,062761,062767,062768,062773,062775,062777,062778,062779,062781,062791,062809,062821,062823,062826,062827,062863,062867,062869,062870,062871,062872,062873,062973,062974,062986,062987,063023,063024,063063,063186,065007,065081,065152,065215,065229,065234,065248,065253,065326,065336,065444,090836,210221","Infection","Antibiotics,Bacterial","Microbiology","Cephalexin (Cefalexin) is an antibiotic that can treat a number of bacterial infections.",347.39,"15686-71-2",0,2,0,0,"http://selleckchem.com/products/Cephalexin-(Cefalexin).html","C16H17N3O4S","free base","Cefalexin","CC1=C(N2C(SC1)C(NC(=O)C(N)C3=CC=CC=C3)C2=O)C(O)=O",-2.255,3,2,4]
["S4482","Palbociclib","c11","L1300-41","in 2mM DMSO","FDA, DMF, EMA, CFDA, NDC, PMDA",null,"207103","Cancer/Endocrinology","CDK","Cell Cycle","Palbociclib (Ibrance, PD 0332991) is a highly specific inhibitor of cyclin-dependent kinase 4 (Cdk4) and Cdk6 with IC50 of 11 nM and 16 nM, respectively.",447.53,"571190-30-2",3,6.7,"<1",0,"http://www.selleckchem.com/products/palbociclib.html","C24H29N7O2","Free Base","Ibrance, PD 0332991","CC(=O)C1=C(C)C2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2N(C5CCCC5)C1=O",2.801,5,2,5]
["S5799","Potassium guaiacolsulfonate hemihydrate","d11","L1300-41","in 2mM DMSO","CFDA","USP–NF 2021(Issue 2), KP Ⅹ, JP17",null,"Inflammation","Others","Others","Potassium guaiacolsulfonate hemihydrate (Potassium Hydroxymethoxybenzenesulfonate, Sulfogaiacol) is used as an expectorant for relieving symptoms of cough and mucus in the chest due to respiratory infections, asthma, colds, or hay fever.",502.6,"78247-49-1",5,9.95,5,9.95,"http://www.selleckchem.com/products/potassium-guaiacolsulfonate-hemihydrate.html","C14H16K2O11S2","Hemihydrate","Potassium Hydroxymethoxybenzenesulfonate, Sulfogaiacol","O.[K+].[K+].COC1=C(O)C=CC(=C1)[S]([O-])(=O)=O.COC2=C(O)C=CC(=C2)[S]([O-])(=O)=O",-2.889,2,2,4]
["E0161","Bictegravir Sodium","e11","L1300-41","in 2mM DMSO","FDA, EMA",null,"210251","Infection","Integrase","Microbiology","Bictegravir (GS-9883) Sodium is a novel and potent inhibitor of HIV-1 integrase, specifically targets IN strand transfer activity with an IC50 of 7.5 nM.",473.38,"1807988-02-8",2,4.22,"<1",0,"http://www.selleckchem.com/products/bictegravir-sodium.html","C21H18F3N3O5.Na","Sodium","GS-9883 Sodium","[NaH].OC1=C2N(CC3OC4CCC(C4)N3C2=O)C=C(C(=O)NCC5=C(F)C=C(F)C=C5F)C1=O",0.65,4,2,3]
["E0524","Spinosad","f11","L1300-41","in 2mM DMSO","FDA,NDC,DMF",null,"022408","Parasitology","AChR,Anti-infection","Neuronal Signaling","Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete, is a biological neurotoxic insecticide with a broader action spectrum, targeting the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system.",731.96,"168316-95-8",3,4.1,"<1",0,"http://www.selleckchem.com/products/spinosad.html","C41H65NO10","free base",0,"NA","NA","NA","NA","NA"]
["S9464","Tranylcypromine Sulfate","g11","L1300-41","in 2mM DMSO","FDA,NDC,DMF","USPNF 2022 Issue 1","213503,206856,040640,012342","Neurological Disease","MAO","Metabolism","Tranylcypromine (Parnate) is an irreversible inhibitor of monoamine oxidase (MAO) with a rapid onset of activity.",364.46,"13492-01-8",2,5.49,"<1",0,"http://www.selleckchem.com/products/tranylcypromine-sulfate.html","C18H24N2O4S","Sulfate","Parnate","NC1CC1C2=CC=CC=C2.NC3CC3C4=CC=CC=C4.O[S;v6](O)(=O)=O",1.78,0,2,2]
["E4160","Glycyl-L-tyrosine","h11","L1300-41","in 2mM DMSO","HMA, DMF","USP-NF2024, USP-NF2023, USP-NF2021",null,"Others","Others","Natural Products","Glycyl-L-tyrosine is a dipeptide containing glycine and L-tyrosine. It is an amino acid inhibitor from potatoes.",238.24,"658-79-7",0,">2",0,0,"https://www.selleckchem.com/products/glycyl-l-tyrosine.html","C11H14N2O4","amino acid","Gly-Tyr","NCC(=O)NC(CC1=CC=C(O)C=C1)C(O)=O",-2.787,2,3,5]
["E4468","Cabotegravir Sodium","a2","L1300-42","in 2mM DMSO","FDA;NDC;PMDA;DMF",null,212887,"HIV-1 infection","Integrase","Microbiology","Cabotegravir (GSK-1265744) sodium is a orally active and long-acting HIV integrase strand transfer inhibitor. It also inhibits organic anion transporter 1/3 (OAT1/OAT3) with IC50 of 0.41 μM and 0.81 μM for OAT3 and OAT1, respectively.",428.34,"1051375-13-3",2,4.67,"<1",0,"https://www.selleckchem.com/products/cabotegravir-sodium.html","C19H17F2N3O5.Na","Sodium","GSK-1265744 sodium","[Na;v0].CC1COC2CN3C=C(C(=O)NCC4=C(F)C=C(F)C=C4)C(=O)C(=C3C(=O)N12)O",0.237,4,2,3]
["S2544","Cefprozil hydrate","b2","L1300-42","in 2mM DMSO","HMA,FDA,NDC,DMF,CFDA","BP2024;USP-NF2024;EP11.0;Martindale: The Complete Drug Reference","065235,065208,065276,065261","Infection","Bacterial","Microbiology","Cefprozil hydrate is a semi-synthetic broad-spectrum cephalosporin <b>antibiotic</b>, used to treat certain infections caused by bacteria, such as bronchitis and infections of the ears, throat, sinuses, and skin.",407.44,"121123-17-9",0,">2",0,0,"https://www.selleckchem.com/products/Cefprozil-hydrate-Cefzil","C18H19N3O5S.H2O",0,0,"[OH2:29].[CH3:12]/[CH:11]=[CH:10]/[C:20]1=[C:16]([N:14]2[CH:15]([S:19][CH2:21]1)[CH:18]([NH:5][C:6](=[O:8])[CH:7]([NH2:9])[C:22]3=[CH:23][CH:25]=[C:27]([OH:13])[CH:26]=[CH:24]3)[C:17]2=[O:4])[C:1]([OH:2])=[O:3]",-2.236,3,3,5]
["S1346","Heparin sodium","a2","L1300-43","in 2mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.3,KP Ⅹ,EP9.1,JP17,BP2017,Ph.Int_5th,IP2010","000552,004570,005521,017007,017029,017033,017037,017064,017130,017346,017486,017540,017651,017780,017979,040007,040008,040095,087043,087077,087107,087363,087395,087452,088099,088100,088239,090571,090808,090809,091659,091682,201002,201370,202733,202957,203198,203851,203852,205323,206552,208827,211005,211007","Cardiovascular Disease/Hematology","Autophagy,Factor Xa,Thrombin","Proteases","Heparin sodium, a sulfated polysaccharide belonging to the family of glycosaminoglycans, has numerous important biological activities associated with its interaction with diverse proteins. Heparin is used as an anticoagulant primarily through its interaction with AT III by enhancing AT-IIImediated inhibition of blood coagulation factors, including thrombin and factor Xa. Heparin prevents the induction of autophagy.","6000-20000","9041-08-1","<1",0,100,8,"http://selleckchem.com/products/Heparin-sodium.html","(C12H16NS2Na3)20","Sodium salt","N/A","CCC1CC(N[R])C(OC1CO[S]([O-])(=O)=O)OC2C(O)C(O)C(OC3C(CO[R])OC(OC4C(O)C(O[S]([O-])(=O)=O)C(OC5C(O)C(N[S]([O-])(=O)=O)C(C)OC5CO[S]([O-])(=O)=O)OC4C([O-])=O)C(N[S]([O-])(=O)=O)C3[S]([O-])(=O)=O)OC2C([O-])=O",-22.565,13,7,27]
["S1428","Risedronate Sodium","b2","L1300-43","in 2mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP39-NF34","077132,079215,090877,090886,200296,200477,203217,203533,203822,205066,205280,206768,207516","Metabolic Disease","Others","Metabolism","Risedronate (NE 58095) sodium, a nitrogen-containing bisphosphonate, inhibits osteoclast-mediated bone resorption and modulates bone metabolism, used in the treatment of osteoporosis.",305.09,"115436-72-1","<1",0,2,6.56,"http://selleckchem.com/products/Risedronate-sodium.html","C7H10NNaO7P2","Sodium salt","NE 58095 Sodium","[Na+].OC(CC1=CC=CN=C1)([P](O)(O)=O)[P](O)([O-])=O",-1.737,1,0,4]
["S1911","Disodium Cromoglycate","c2","L1300-43","in 2mM Water","DMF,HMA",null,null,"Immunology/Inflammation/Ophthalmology","Calcium Channel","Transmembrane Transporters","Disodium Cromoglycate (Gynazole ,FPL 670 (Cromolyn) Disodium,Cromolyn sodium) is an antiallergic drug with IC50 of 39 μg/mL.",512.33,"15826-37-6","<1",0,2,3.9,"http://selleckchem.com/products/disodium-Cromoglycate.html","C23H14O11.2Na","Disodium Salt","Gynazole ,FPL 670 (Cromolyn) Disodium,Cromolyn sodium","[Na+].[Na+].OC(COC1=C2C(=O)C=C(OC2=CC=C1)C([O-])=O)COC3=CC=CC4=C3C(=O)C=C(O4)C([O-])=O",-1.178,6,1,8]
["S1982","Adenine sulfate","d2","L1300-43","in 2mM Water","DMF,NDC,PMDA","USP42-NF37",null,"Nutritional support","DNA/RNA Synthesis","DNA Damage/DNA Repair","Adenine sulfate(Adenine hemisulfate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.",368.33,"321-30-2","<1",0,2,5.43,"http://selleckchem.com/products/adenine-sulfate.html","2(C5H5N5).H2SO4","Sulfate","Adenine hemisulfate","NC1=NC=NC2=C1[NH]C=N2.NC3=NC=NC4=C3[NH]C=N4.O[S](O)(=O)=O",-1.498,6,4,0]
["S2106","Azasetron HCl","e2","L1300-43","in 2mM Water","CFDA,PMDA","Martindale:The Extra Pharmacopoeia",null,"Gastroenterology","5-HT Receptor","Neuronal Signaling","Azasetron HCl (Y-25130) is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.",386.27,"123040-16-4","<1",0,3,7.77,"http://selleckchem.com/products/azasetron-hcl.html","C17H20ClN3O3.HCl","HCl","Y-25130 HCl","Cl.CN1C(=O)COC2=C(C=C(Cl)C=C12)C(=O)NC3CN4CCC3CC4",1.616,3,1,2]
["S2562","Hydralazine HCl","f2","L1300-43","in 2mM Water","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","040136,040373,040388,040730,040858,040901,083241,083560,083561,084106,084107,084437,084443,084469,084503,084504,084581,084922,084923,085088,085532,085533,086088,086242,086243,086961,086962,087712,087751,087780,087836,087908,088177,088178,088240,088241,088310,088311,088391,088467,088468,088517,088518,088560,088649,088652,088657,088671,088686,088728,088729,088787,088788,088789,088846,088847,088848,088849,089097,089098,089130,089178,089218,089222,089258,089259,089359,089532,090255,090413,090527,091679,200737,200770,202938,203110,203845,204680,205236,209251","Cardiovascular Disease","Potassium Channel","Transmembrane Transporters","Hydralazine HCl is a hydrochloride salt of hydralazine, which is a direct-acting smooth muscle relaxant used to treat hypertension by acting as a vasodilator primarily in arteries and arterioles.",196.64,"304-20-1","<1",0,1,5.09,"http://selleckchem.com/products/Hydralazine-hydrochloride.html","C8H8N4.HCl","Hydrochloride","N/A","Cl.N/N=C/1NN=CC2=C1C=CC=C2",0.798,2,2,0]
["S3055","Besifloxacin HCl","g2","L1300-43","in 2mM Water","FDA,DMF,NDC",null,"022308","Infection/Inflammation","Antibiotics","Microbiology","Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic.",430.3,"405165-61-9","<1",0,1,2.32,"http://selleckchem.com/products/besifloxacin-hci.html","C19H21ClFN3O3.HCl","Hydrochloride","N/A","Cl.NC1CCCCN(C1)C2=C(Cl)C3=C(C=C2F)C(=O)C(=CN3C4CC4)C(O)=O",0.698,2,1,3]
["S3749","Calcium gluconate monohydrate","h2","L1300-43","in 2mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","208418","Cardiovascular Disease","Others","Others","Calcium gluconate (Calcarea gluconica, Calcium gluconate anhydrous, Calcium D-gluconate, Calciofon, Glucobiogen) is element or mineral necessary for normal nerve, muscle, and cardiac function. Calcium as the gluconate salt helps to maintain calcium balance and prevent bone loss when taken orally.",448.39,"66905-23-5","<1",0,4,8.92,"http://selleckchem.com/products/calcium-gluconate.html","C12H22O14.Ca.H2O","monohydrate","Calcarea gluconica, Calcium gluconate anhydrous, Calcium D-gluconate, Calciofon, Glucobiogen","O.[Ca++].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O",-8.781,0,10,10]
["S4067","Deferiprone","a3","L1300-43","in 2mM Water","FDA,DMF,EMA,HMA,NDC","Martindale:The Extra Pharmacopoeia,EP9.5","208800","Hematology","Others","Others","Deferiprone (CP20) is a chelating agent with an affinity for ferric ion (iron III)，binds with ferric ions to form neutral 3:1 (deferiprone:iron) complexes that are stable over a wide range of pH values.",139.15,"30652-11-0","<1",0,1,7.19,"http://selleckchem.com/products/deferiprone.html","C7H9NO2","Free Base","CP20","CN1C=CC(=O)C(=C1C)O",-0.139,1,1,0]
["S4153","D-Phenylalanine","b3","L1300-43","in 2mM Water","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017",null,"Cardiovascular Disease/Endocrinology/Metabolic Disease","Others","Endocrinology & Hormones","D-Phenylalanine, a carboxypeptidase A, endorphinase and enkephalinase inhibitor, enhances endorphin production and diminishes pain.",165.19,"673-06-3","<1",0,1,6.05,"http://selleckchem.com/products/d-phenylalanine.html","C9H11NO2","Free Base","N/A","NC(CC1=CC=CC=C1)C(O)=O",-1.605,1,1,3]
["S4226","Minocycline (CL 59806) HCl","c3","L1300-43","in 2mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","050451,063009,063011,063065,063181,065005,065062,065131,065156,065436,065470,065485,090024,090217,090422,090422,090867,090911,091118,091118,091424,201467,202261,202261,203443,203443,203553,203553,204394,204453,204453","Infection","Antibiotics","Microbiology","Minocycline (CL 59806,Minocin) HCl is the most lipid soluble and most active tetracycline antibiotic, binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis.",493.94,"13614-98-7","<1",0,1,2.02,"http://selleckchem.com/products/minocycline-hcl.html","C23H27N3O7.HCl","Hydrochloride","Minocin","Cl.CN(C)C1C2CC3CC4=C(C(=CC=C4N(C)C)O)C(=O)C3=C(O)C2(O)C(=O)C(=C1O)C(N)=O",0,0,0,0]
["S4694","Alosetron Hydrochloride","d3","L1300-43","in 2mM Water","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","200652,206113,206647,209180","Cardiovascular Disease","5-HT Receptor","Neuronal Signaling","Alosetron Hydrochloride (GR 68755C, GR 68755X, Lotronex) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist.",330.81,"122852-69-1","<1",0,1,3.02,"http://selleckchem.com/products/alosetron-hydrochloride.html","C17H18N4O.HCl","hydrochloride","GR 68755C, GR 68755, GR 68755X, Lotronex, GR-68755, GR68755","Cl.C[N]1C2=C(C(=O)N(CC2)CC3=C(C)N=C[NH]3)C4=C1C=CC=C4",2.036,2,1,2]
["S5355","Piperaquine phosphate","e3","L1300-43","in 2mM Water","CFDA","Martindale:The Extra Pharmacopoeia",null,"Infection/Parasitology","Anti-infection","Microbiology","Piperaquine phosphate is an orally active bisquinolone antimalarial drug.",633.51,"85547-56-4","<1",0,2,3.16,"http://selleckchem.com/products/piperaquine-phosphate.html","C29H32Cl2N6.H3O4P","phosphate","N/A","O[P](O)(O)=O.ClC1=CC=C2C(=C1)N=CC=C2N3CCN(CCCN4CCN(CC4)C5=C6C=CC(=CC6=NC=C5)Cl)CC3",5.012,2,0,6]
["S5695","Icatibant Acetate","f3","L1300-43","in 2mM Water","DMF,EMA,NDC,FDA,marketed in Japan","Martindale:The Extra Pharmacopoeia","022150","Angiology","Bradykinin Receptor","GPCR & G Protein","Icatibant Acetate(HOE-140 acetate) acts as an antagonist of the bradykinin B2 receptor and is used in the treatment of hereditary angioedema.",1364.57,"138614-30-9",-1,0,11,8.06,"http://www.selleckchem.com/products/icatibant-acetate.html","C61H93N19O15S","Acetate","HOE-140 acetate","CC(O)=O.NC(CCCNC(N)=N)C(=O)NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)N2CC(O)CC2C(=O)NCC(=O)NC(CC3=CC=CS3)C(=O)NC(CO)C(=O)N4CC5=C(CC4C(=O)N6C7CCCCC7CC6C(=O)NC(CCCNC(N)=N)C(O)=O)C=CC=C5",-6.943,11,14,33]
["S8030","Plerixafor (AMD3100)","g3","L1300-43","in 2mM Water","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","022311","Immunology","CXCR,HIV","GPCR & G Protein","Plerixafor (AMD3100, JM 3100, SID791) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively. Plerixafor inhibits human immunodeficiency virus (HIV) replication.",502.78,"110078-46-1","<1",0,3,5.97,"http://selleckchem.com/products/plerixafor.html","C28H54N8","Free Base","JM 3100, SID791","C1CNCCNCCCN(CCNC1)CC2=CC=C(CN3CCCNCCNCCCNCC3)C=C2",-0.52,0,6,4]
["S5650","Sodium Hyaluronate","h3","L1300-43","in 2mM Water","DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,BP2017,IP2010",null,"Inflammation/Ophthalmology","Others","Others","Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan found in various connective tissue of humans.",401.3,"9067-32-7","The physical form of the compound is liquid, which can be dissolved in any proportion.",0,0,2,"https://www.selleckchem.com/products/sodium-hyaluronate.html","C14H20NNaO11R","free base",0,"[Na+].CC(=O)NC1C(C(O)C(CO)OC1OC2C(O)C(O)C(O[*])OC2C([O-])=O)[*]",-4.314,5,5,6]
["S2095","Fosinopril Sodium","a4","L1300-43","in 2mM Water","FDA,DMF,CFDA,NDC,HMA","EP9.1,BP2017,USP39-NF34","076139,076188,076483,076580,076620,076906,076987,077222,077531,091163,205670","Cardiovascular Disease","ACE,RAAS","Endocrinology & Hormones","Fosinopril Sodium (SQ28555) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.",585.64,"88889-14-9",0,0,0,2,"http://selleckchem.com/products/fosinopril-sodium-monopril.html","C30H45NO7P.Na","Sodium Salt","SQ28555","[Na+].CCC(=O)OC(O[P](=O)(CCCCC1=CC=CC=C1)CC(=O)N2CC(CC2C([O-])=O)C3CCCCC3)C(C)C",4.129,5,0,15]
["S2050","Strontium Ranelate","b4","L1300-43","in 2mM Water","FDA,EMA,HMA,CFDA,PMDA,NDC,DMF","USPNF 2022 Issue 1,EP10.8","202342,075941,020134","Gastroenterology;Inflammation,Infection","Calcium Channel","Transmembrane Transporters","Strontium Ranelate is a strontium(II) salt of ranelic acid for (-)-desmethoxyverapamil binding to calcium channel with IC50 of 0.5 mM.",513.49,"135459-87-9","<1",0,2,3.89,"http://www.selleckchem.com/products/strontium-ranelate-protelos.html","C12H6N2O8S.2Sr","Free base","N/A","O=C1CN(CC(=O)O[Sr]O1)C2=C(C#N)C3=C(S2)C(=O)O[Sr]OC(=O)C3",0.569,8,0,1]
["S5264","L-5-Methyltetrahydrofolate calcium","c4","L1300-43","in 2mM Water","DMF,NDC","USP-NF2024",null,"Cancer","Others","Others","Calcium L-5-methyltetrahydrofolate (L-5-MTHF-Ca) is a synthetic derivative of folic acid, the predominant, naturally occurring form of folate.",497.52,"151533-22-1","<1",0,1,2.01,"http://www.selleckchem.com/products/l-5-methyltetrahydrofolate-calcium.html","C20H23N7O6.Ca","Calcium salt","L-5-MTHF-Ca","[Ca++].CN1C(CNC2=CC=C(C=C2)C(=O)NC(CCC([O-])=O)C([O-])=O)CNC3=C1C(=O)NC(=N3)N",-3.742,3,5,9]
["S4444","Hypromellose","a2","L1300-44","in 2mg/ml DMSO","NDC, HMA, DMF","JP18, BP2023, USP-NF2024","M018","Others","others","others","Hypromellose (Hydroxypropyl Methyl Cellulose, HPMC, Celacol HPM 5000) is a commonly employed cellulose ether used in the fabrication of hydrophilic matrices. Hypromellose provides the release of a drug in a controlled manner, effectively increasing the duration of release of a drug to prolong its therapeutic effect.",0,"9004-65-3",100,0,100,0,"https://www.selleckchem.com/products/hypromellose.html","N/A","Free Base","Hydroxypropyl Methyl Cellulose, HPMC, Celacol HPM 5000, Hydroxypropylmethyl cellulose",0,0,0,0,0]
["S3505","Polidocanol","b2","L1300-44","in 2mg/ml DMSO","FDA; NDC; PMDA",null,"021201, 205098","Cardiovascular Disease","others","others","Polidocanol (Polyoxyethylene lauryl ether, Polyoxyethyleneglycol Dodecyl Ether, Brij30, Laureth-23, Varithena) is a sclerosant used for treating uncomplicated spider veins and reticular veins in the lower extremities.",0,"9002-92-0",100,0,100,0,"https://www.selleckchem.com/products/polidocanol.html","(C2H4O)nC12H26O","Free Base","Polyoxyethylene lauryl ether, Polyoxyethyleneglycol Dodecyl Ether, Brij30, Laureth-23, Varithena","CCCCCCCCCCCCOCCO",4.489,1,1,13]