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,[880,1,881,1],[880,2,881,2],[882,1,883,1],[882,2,883,2],[884,1,885,1],[884,2,885,2],[886,1,887,1],[886,2,887,2],[888,1,889,1],[888,2,889,2],[890,1,891,1],[890,2,891,2],[892,1,893,1],[892,2,893,2],[897,1,897,13],[899,1,900,1],[899,2,900,2],[901,1,902,1],[901,2,902,2],[903,1,904,1],[903,2,904,2],[905,1,906,1],[905,2,906,2],[907,1,908,1],[907,2,908,2],[909,1,910,1],[909,2,910,2],[911,1,912,1],[911,2,912,2],[913,1,914,1],[913,2,914,2],[918,1,918,13],[920,1,921,1],[920,2,921,2],[922,1,923,1],[922,2,923,2],[924,1,925,1],[924,2,925,2],[926,1,927,1],[926,2,927,2],[928,1,929,1],[928,2,929,2],[930,1,931,1],[930,2,931,2],[932,1,933,1],[932,2,933,2],[934,1,935,1],[934,2,935,2],[939,1,939,13],[941,1,942,1],[941,2,942,2],[943,1,944,1],[943,2,944,2],[945,1,946,1],[945,2,946,2],[947,1,948,1],[947,2,948,2],[947,6,948,6],[949,1,950,1],[949,2,950,2],[951,1,952,1],[951,2,952,2],[953,1,954,1],[953,2,954,2],[955,1,956,1],[955,2,956,2],[960,1,960,13],[962,1,963,1],[962,2,963,2],[964,1,965,1],[964,2,965,2],[966,1,967,1],[966,2,967,2],[968,1,969,1],[968,2,969,2],[970,1,971,1],[970,2,971,2],[972,1,973,1],[972,2,973,2],[974,1,975,1],[974,2,975,2],[976,1,977,1],[976,2,977,2],[981,1,981,13],[983,1,984,1],[983,2,984,2],[985,1,986,1],[985,2,986,2],[987,1,988,1],[987,2,988,2],[989,1,990,1],[989,2,990,2],[991,1,992,1],[991,2,992,2],[993,1,994,1],[993,2,994,2],[995,1,996,1],[995,2,996,2],[997,1,998,1],[997,2,998,2],[1002,1,1002,13],[1004,1,1005,1],[1004,2,1005,2],[1006,1,1007,1],[1006,2,1007,2],[1008,1,1009,1],[1008,2,1009,2],[1010,1,1011,1],[1010,2,1011,2],[1012,1,1013,1],[1012,2,1013,2],[1014,1,1015,1],[1014,2,1015,2],[1016,1,1017,1],[1016,2,1017,2],[1018,1,1019,1],[1018,2,1019,2],[1023,1,1023,13],[1025,1,1026,1],[1025,2,1026,2],[1027,1,1028,1],[1027,2,1028,2],[1029,1,1030,1],[1029,2,1030,2],[1031,1,1032,1],[1031,2,1032,2],[1033,1,1034,1],[1033,2,1034,2],[1035,1,1036,1],[1035,2,1036,2],[1037,1,1038,1],[1037,2,1038,2],[1039,1,1040,1],[1039,2,1040,2],[1044,1,1044,13],[1046,1,1047,1],[1046,2,1047,2],[1048,1,1049,1],[1048,2,1049,2],[1050,1,1051,1],[1050,2,1051,2],[1052,1,1053,1],[1052,2,1053,2],[1054,1,1055,1],[1054,2,1055,2],[1056,1,1057,1],[1056,2,1057,2],[1058,1,1059,1],[1058,2,1059,2],[1060,1,1061,1],[1060,2,1061,2],[1065,1,1065,13],[1067,1,1068,1],[1067,2,1068,2],[1069,1,1070,1],[1069,2,1070,2],[1071,1,1072,1],[1071,2,1072,2],[1073,1,1074,1],[1073,2,1074,2],[1075,1,1076,1],[1075,2,1076,2],[1077,1,1078,1],[1077,2,1078,2],[1079,1,1080,1],[1079,2,1080,2],[1081,1,1082,1],[1081,2,1082,2],[1086,1,1086,13],[1088,1,1089,1],[1088,2,1089,2],[1090,1,1091,1],[1090,2,1091,2],[1092,1,1093,1],[1092,2,1093,2],[1094,1,1095,1],[1094,2,1095,2],[1096,1,1097,1],[1096,2,1097,2],[1098,1,1099,1],[1098,2,1099,2],[1100,1,1101,1],[1100,2,1101,2],[1102,1,1103,1],[1102,2,1103,2],[1107,1,1107,13],[1109,1,1110,1],[1109,2,1110,2],[1111,1,1112,1],[1111,2,1112,2],[1113,1,1114,1],[1113,2,1114,2],[1115,1,1116,1],[1115,2,1116,2],[1117,1,1118,1],[1117,2,1118,2],[1119,1,1120,1],[1119,2,1120,2],[1121,1,1122,1],[1121,2,1122,2],[1123,1,1124,1],[1123,2,1124,2],[1128,1,1128,13],[1130,1,1131,1],[1130,2,1131,2],[1132,1,1133,1],[1132,2,1133,2],[1134,1,1135,1],[1134,2,1135,2],[1134,3,1135,3],[1136,1,1137,1],[1136,2,1137,2],[1138,1,1139,1],[1138,2,1139,2],[1140,1,1141,1],[1140,2,1141,2],[1142,1,1143,1],[1142,2,1143,2],[1144,1,1145,1],[1144,2,1145,2],[1149,1,1149,13],[1151,1,1152,1],[1151,2,1152,2],[1153,1,1154,1],[1153,2,1154,2],[1155,1,1156,1],[1155,2,1156,2],[1157,1,1158,1],[1157,2,1158,2],[1157,5,1158,5],[1159,1,1160,1],[1159,2,1160,2],[1159,5,1160,5],[1161,1,1162,1],[1161,2,1162,2],[1161,5,1162,5],[1163,1,1164,1],[1163,2,1164,2],[1163,5,1164,5],[1165,1,1166,1],[1165,2,1166,2],[1165,5,1166,5],[1170,1,1170,13],[1172,1,1173,1],[1172,2,1173,2],[1172,4,1173,4],[1172,5,1173,5],[1174,1,1175,1],[1174,2,1175,2],[1174,4,1175,4],[1174,5,1175,5],[1176,1,1177,1],[1176,2,1177,2],[1176,3,1177,3],[1176,4,1177,4],[1176,5,1177,5],[1178,1,1179,1],[1178,2,1179,2],[1178,3,1179,3],[1178,4,1179,4],[1178,5,1179,5],[1180,1,1181,1],[1180,2,1181,2],[1180,3,1181,3],[1180,4,1181,4],[1180,5,1181,5],[1182,1,1183,1],[1182,2,1183,2],[1182,3,1183,3],[1182,4,1183,4],[1182,5,1183,5],[1184,1,1185,1],[1184,2,1185,2],[1184,3,1185,3],[1184,4,1185,4],[1184,5,1185,5],[1186,1,1187,1],[1186,2,1187,2],[1186,3,1187,3],[1186,4,1187,4],[1186,5,1187,5]],"merged_total":1698,"flags":["merged_cut"]}
[{"$nulls":3},"FDA-approved & Passed Phase I Drug Library (96-well)-L3800"]
[null,"For more information on Selleck library service, please contact us via +1-832-582-8158 or library@selleckchem.com"]
[]
[null,"Product Details:"]
[null,"Description",null,"A unique collection of 4200 compounds"]
[null,"Container",null,"96 Well"]
[null,"Stability",null,"12 months | ﹣20°C | in DMSO"]
[{"$nulls":3},"24 months | ﹣80°C | in DMSO"]
[null,"Shipping",null,"Blue ice or Dry ice"]
[null,"Formulation",null,"Solubility ≥10 mM pre-dissolved in 10 mM solution and solubility between 2 mM and 10 mM pre-dissolved in 2 mM solution"]
[{"$nulls":3},"In 10 mM DMSO : Plate layout L3800-01~48;    In 10 mM Water : Plate layout L3800-49~52;"]
[{"$nulls":3},"In 2 mM DMSO : Plate layout L3800-53~54;    In 2 mM Water  : Plate layout L3800-55;"]
[{"$nulls":3},"In 2mg/ml DMSO : Plate layout L3800-56"]
[]
[]
[null,"Plate layout: L3800-01"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1003","S1013","S1026","S1039","S1055","S1078","S1094","S1107","S1120","S1141","Empty"]
[{"$nulls":3},"Linifanib (ABT-869)","Bortezomib (PS-341)","Imatinib (STI571) Mesylate","Rapamycin (AY-22989)","Enzastaurin (LY317615)","MK-2206 2HCl","PF-04217903","Danusertib (PHA-739358)","Everolimus (RAD001)","Tanespimycin (17-AAG)"]
[null,"b","Empty","S1004","S1014","S1028","S1040","S1057","S1082","S1095","S1109","S1122","S1142","Empty"]
[{"$nulls":3},"Veliparib (ABT-888)","Bosutinib (SKI-606)","Lapatinib (GW-572016) Ditosylate","Sorafenib (BAY 43-9006) tosylate","Obatoclax Mesylate (GX15-070)","Vismodegib (GDC-0449)","Dacinostat (LAQ824)","BI 2536","Mocetinostat (MGCD0103)","Alvespimycin (17-DMAG) HCl"]
[null,"c","Empty","S1005","S1017","S1029","S1042","S1060","S1084","S1096","S1110","S1124","S1144","Empty"]
[{"$nulls":3},"Axitinib (AG 013736)","Cediranib (AZD2171)","Lenalidomide (CC-5013)","Sunitinib (SU11248) malate","Olaparib (AZD2281)","Brivanib (BMS-540215)","Quisinostat (JNJ-26481585) 2HCl","Varespladib (LY315920)","BMS-754807","Ivacaftor (VX-770)"]
[null,"d","Empty","S1006","S1018","S1030","S1044","S1064","S1085","S1098","S1111","S1130","S1145","Empty"]
[{"$nulls":3},"Saracatinib (AZD0530)","Dovitinib (TKI-258)","Panobinostat (LBH589)","Temsirolimus (CCI-779)","Masitinib (AB1010)","Belinostat (PXD101)","Rucaparib (AG-014699) phosphate","Foretinib (GSK1363089)","Sepantronium Bromide","SNS-032 (BMS-387032)"]
[null,"e","Empty","S1007","S1020","S1032","S1047","S1065","S1087","S1100","S1113","S1133","S1147","Empty"]
[{"$nulls":3},"Roxadustat (FG-4592)","PD184352 (CI-1040)","Motesanib Diphosphate (AMG-706)","Vorinostat (SAHA)","Pictilisib (GDC-0941)","Iniparib (BSI-201)","MLN8054","GSK690693","Alisertib (MLN8237)","Barasertib (AZD1152-HQPA)"]
[null,"f","Empty","S1008","S1021","S1033","S1048","S1068","S1089","S1101","S1114","S1134","S1148","Empty"]
[{"$nulls":3},"Selumetinib (AZD6244)","Dasatinib (BMS-354825)","Nilotinib (AMN-107)","Tozasertib","Crizotinib (PF-02341066)","Refametinib (RDEA119)","Vatalanib (PTK787) 2HCl","JNJ-38877605","AT9283","Docetaxel (RP56976)"]
[null,"g","Empty","S1010","S1022","S1035","S1052","S1069","S1090","S1105","S1117","S1137","S1150","Empty"]
[{"$nulls":3},"Nintedanib (BIBF 1120)","Ridaforolimus (Deforolimus, MK-8669)","Pazopanib HCl (GW786034 HCl)","Elesclomol (STA-4783)","Luminespib (NVP-AUY922)","Abexinostat (PCI-24781)","LY294002","Triciribine (NSC 154020)","Malotilate","Paclitaxel (NSC 125973)"]
[null,"h","Empty","S1011","S1025","S1036","S1053","S1072","S1091","S1106","S1119","S1138","S1152","Empty"]
[{"$nulls":3},"Afatinib (BIBW2992)","Gefitinib (ZD1839)","Mirdametinib (PD0325901)","Entinostat (MS-275)","ZSTK474","Linsitinib (OSI-906)","OSU-03012 (AR-12)","Cabozantinib (BMS-907351)","Brivanib Alaninate (BMS-582664)","PLX-4720"]
[]
[]
[]
[null,"Plate layout: L3800-02"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1153","S1165","S1183","S1194","S1206","S1218","S1230","S1244","S1257","S1276","Empty"]
[{"$nulls":3},"Roscovitine (CYC202)","ABT-751 (E7010)","Danoprevir (ITMN-191)","CUDC-101","Bisoprolol fumarate","Clofarabine","Flavopiridol (L86-8275)","Amuvatinib (MP-470)","Posaconazole (SCH 56592)","Adapalene"]
[null,"b","Empty","S1156","S1168","S1185","S1196","S1207","S1220","S1231","S1245","S1258","S1278","Empty"]
[{"$nulls":3},"Capecitabine (RO 09-1978)","Valproic Acid (NSC 93819) sodium salt","Ritonavir (ABT-538)","Exemestane (FCE 24304)","Tivozanib (AV-951)","OSI-930","Topotecan (NSC609699) HCl","Latrepirdine 2HCl","Prasugrel","Altretamine"]
[null,"c","Empty","S1157","S1171","S1188","S1197","S1208","S1221","S1233","S1247","S1259","S1280","Empty"]
[{"$nulls":3},"Delanzomib (CEP-18770)","CYC116","Anastrozole (ZD-1033)","Finasteride","Doxorubicin (Adriamycin) HCl","Dacarbazine (NSC-45388)","2-Methoxyestradiol (2-MeOE2)","Leflunomide (HWA486)","Ramelteon","Amisulpride"]
[null,"d","Empty","S1158","S1172","S1189","S1199","S1209","S1222","S1235","S1250","S1260","S1281","Empty"]
[{"$nulls":3},"MK-8245","Serdemetan (JNJ-26854165)","Aprepitant (MK-0869)","Cladribine (RWJ 26251)","Fluorouracil (5-Fluorouracil, 5-FU)","Dexrazoxane HCl (ICRF-187)","Letrozole (CGS 20267)","Enzalutamide (MDV3100)","Cinacalcet (AMG-073) HCl","Aniracetam"]
[null,"e","Empty","S1159","S1175","S1190","S1200","S1210","S1223","S1237","S1251","S1261","S1282","Empty"]
[{"$nulls":3},"Ganetespib (STA-9090)","BIIB021","Bicalutamide (ICI-176334)","Decitabine (NSC 127716)","Methotrexate (CL-14377)","Epirubicin (IMI 28) HCl","Temozolomide (CCRG 81045)","Dienogest","Celecoxib (SC 58635)","Artemisinin"]
[null,"f","Empty","S1162","S1176","S1191","S1201","S1212","S1225","S1238","S1252","S1262","S1283","Empty"]
[{"$nulls":3},"Pretomanid (PA-824)","Plinabulin (NPI-2358)","Fulvestrant (ICI-182780)","Dimesna","Bendamustine (SDX105) HCl","Etoposide (VP-16)","Tamoxifen (ICI 46474)","Entecavir Hydrate","Avagacestat (BMS-708163)","Asenapine maleate"]
[null,"g","Empty","S1163","S1178","S1192","S1202","S1213","S1227","S1241","S1255","S1267","S1284","Empty"]
[{"$nulls":3},"Onalespib (AT13387)","Regorafenib (BAY 73-4506)","Raltitrexed","Dutasteride","Nelarabine","Raloxifene HCl","Vincristine (NSC-67574) sulfate","Nepafenac","Vemurafenib (PLX4032)","Benazepril HCl"]
[null,"h","Empty","S1164","S1181","S1193","S1204","S1214","S1229","S1243","S1256","S1271","S1286","Empty"]
[{"$nulls":3},"Lenvatinib (E7080)","ENMD-2076","Thalidomide (K17)","Melatonin (NSC 113928)","Bleomycin (NSC125066) sulfate","Fludarabine Phosphate","Agomelatine (S20098)","Rufinamide","Acarbose","Budesonide"]
[]
[]
[]
[null,"Plate layout: L3800-03"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1287","S1304","S1331","S1351","S1362","S1376","S1386","S1396","S1407","S1432","Empty"]
[{"$nulls":3},"Bumetanide","Megestrol Acetate","Fluconazole (UK 49858)","Ivermectin (MK-933)","Rigosertib (ON-01910)","Gestodene","Nafamostat mesilate (FUT-175)","Resveratrol (SRT501)","Bimatoprost","Sumatriptan Succinate"]
[null,"b","Empty","S1289","S1305","S1332","S1352","S1364","S1377","S1387","S1397","S1408","S1435","Empty"]
[{"$nulls":3},"Carmofur","Mercaptopurine (6-MP)","Flumazenil (RO 15-1788)","TG100-115","Patupilone (Epothilone B)","Drospirenone","Naftopidil DiHCl","Rocuronium Bromide","Linezolid (PNU-100766)","Tamsulosin hydrochloride"]
[null,"c","Empty","S1291","S1319","S1333","S1354","S1366","S1378","S1389","S1398","S1409","S1437","Empty"]
[{"$nulls":3},"Cetirizine DiHCl","Costunolide","Fluoxetine (Lilly 110140) HCl","Lansoprazole","BMS-707035","Ruxolitinib (INCB018424)","Omeprazole","Stavudine (d4T)","Alfuzosin HCl","Tizanidine HCl"]
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[{"$nulls":3},"Cilnidipine (FRC-8653)","Dexamethasone (MK-125)","Flupirtine maleate","Levetiracetam (UCB-L059)","Amonafide","Isotretinoin","Ondansetron HCl","Tenofovir (GS 1278) Disoproxil Fumarate","Clopidogrel (SR-25990C) Bisulfate","Topiramate"]
[null,"e","Empty","S1294","S1324","S1336","S1357","S1368","S1380","S1391","S1401","S1425","S1439","Empty"]
[{"$nulls":3},"Cilostazol (OPC-13013)","Doxazosin Mesylate","Fluvoxamine (DU-23000) maleate","Lidocaine","Acitretin","Lopinavir (ABT-378)","Oxcarbazepine","Tenofovir","Ranolazine 2HCl","Tranilast (SB 252218)"]
[null,"f","Empty","S1299","S1326","S1340","S1358","S1369","S1381","S1392","S1403","S1426","S1441","Empty"]
[{"$nulls":3},"Floxuridine (NSC 27640)","Edaravone","Gatifloxacin","Loratadine (SCH29851)","Bafetinib (INNO-406)","Meropenem","Pelitinib (EKB-569)","Tigecycline (GAR-936)","Repaglinide","Venlafaxine HCl"]
[null,"g","Empty","S1300","S1328","S1342","S1359","S1373","S1382","S1393","S1404","S1430","S1442","Empty"]
[{"$nulls":3},"Tegafur (FT-207)","Etodolac","Genistein (NPI 031L)","Losartan Potassium (DuP 753)","Daptomycin (LY146032)","Mianserin HCl","Pirarubicin (NSC-333054)","Trilostane","Rolipram (ZK-62711)","Voriconazole (UK-109496)"]
[null,"h","Empty","S1302","S1330","S1344","S1361","S1374","S1385","S1394","S1405","S1431","S1443","Empty"]
[{"$nulls":3},"Ifosfamide (NSC109724)","Felbamate","Glimepiride","MGCD-265 analog","Doripenem Hydrate","Mosapride Citrate","Pizotifen Malate","Vecuronium Bromide","Sildenafil Citrate","Zileuton (A-64077)"]
[]
[]
[]
[null,"Plate layout: L3800-04"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1444","S1462","S1483","S1499","S1514","S1533","S1550","S1573","S1603","S1611","Empty"]
[{"$nulls":3},"Ziprasidone HCl","AZD6482","Iloperidone","Cefaclor","Cyclosporine","R406 (free base)","Pimobendan","Fasudil (HA-1077) HCl","Furosemide (NSC 269420)","Cefoperazone"]
[null,"b","Empty","S1445","S1465","S1485","S1500","S1515","S1537","S1553","S1574","S1604","S1613","Empty"]
[{"$nulls":3},"Zonisamide","Moxifloxacin (BAY12-8039) HCl","HMN-214","Betamethasone","Pracinostat (SB939)","Vadimezan (ASA404)","Delafloxacin (ABT-492)","Doramapimod (BIRB 796)","Olmesartan Medoxomil","Silodosin"]
[null,"c","Empty","S1452","S1467","S1486","S1501","S1517","S1538","S1555","S1576","S1605","S1614","Empty"]
[{"$nulls":3},"Ispinesib (SB-715992)","Doxercalciferol","AEE788 (NVP-AEE788)","Mycophenolate mofetil (RS-61443)","Natamycin","Telaprevir (VX-950)","AZD8055","Sulfasalazine (NSC 667219)","Cefdinir","Riluzole (PK 26124)"]
[null,"d","Empty","S1453","S1468","S1487","S1504","S1524","S1540","S1557","S1578","S1606","S1618","Empty"]
[{"$nulls":3},"Tipifarnib (R115777)","Alfacalcidol","PHA-793887","Dyphylline","AT7519","Saxagliptin (BMS-477118)","KRN 633","Candesartan (CV-11974)","Clotrimazole","Sulfameter"]
[null,"e","Empty","S1455","S1470","S1488","S1505","S1525","S1541","S1561","S1591","S1607","S1619","Empty"]
[{"$nulls":3},"Cilomilast","Orantinib (SU6668)","Naratriptan HCl","Aztreonam","Adavosertib (MK-1775)","Selisistat (EX 527)","BMS-777607","Bestatin (NK421)","Rizatriptan Benzoate","Prilocaine"]
[null,"f","Empty","S1456","S1472","S1490","S1508","S1526","S1547","S1565","S1593","S1608","S1620","Empty"]
[{"$nulls":3},"Zibotentan (ZD4054)","Safinamide Mesylate","Ponatinib (AP24534)","Alprostadil","Quizartinib (AC220)","Febuxostat","Lumacaftor (VX-809)","Apixaban (BMS 562247-01)","Pyridostigmine Bromide","Darunavir Ethanolate"]
[null,"g","Empty","S1457","S1475","S1491","S1511","S1528","S1548","S1567","S1594","S1609","S1622","Empty"]
[{"$nulls":3},"Atazanavir (BMS-232632) Sulfate","Pimasertib (AS-703026)","Fludarabine (NSC 118218)","Lactulose","LY2811376","Dapagliflozin (BMS-512148)","Pomalidomide (CC-4047)","Semagacestat (LY450139)","Methimazole","Prednisone (NSC-10023)"]
[null,"h","Empty","S1458","S1482","S1497","S1512","S1532","S1549","S1569","S1601","S1610","S1625","Empty"]
[{"$nulls":3},"Neflamapimod (VX-745)","Daclatasvir (BMS-790052)","Pralatrexate (NSC 754230)","Tadalafil (IC351)","AZD7762","Nebivolol hydrochloride (R-65824)","Tazarotene","Reserpine","Metolazone","Ethinyl Estradiol"]
[]
[]
[]
[null,"Plate layout: L3800-05"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1626","S1636","S1646","S1657","S1675","S1688","S1702","S1714","S1725","S1736","Empty"]
[{"$nulls":3},"Naproxen Sodium","Amphotericin B","Ketorolac","Enalaprilat Dihydrate","Lubiprostone","Betamethasone Dipropionate","Didanosine","Gemcitabine (LY-188011)","Terbinafine","Methocarbamol"]
[null,"b","Empty","S1627","S1638","S1647","S1658","S1676","S1689","S1703","S1715","S1727","S1737","Empty"]
[{"$nulls":3},"Nitazoxanide (NSC 697855)","Ibuprofen (NSC 256857)","Adenosine","Dofetilide","Amorolfine HCl","Meprednisone","Divalproex Sodium","Glipizide","Levonorgestrel","Prednisolone (NSC-9900)"]
[null,"c","Empty","S1628","S1639","S1649","S1662","S1677","S1690","S1704","S1716","S1729","S1738","Empty"]
[{"$nulls":3},"Triamcinolone Acetonide","Amprenavir (VX-478)","Zolmitriptan","Isradipine","Chloramphenicol","Betamethasone Valerate","Emtricitabine (BW 1592)","Glyburide (Glibenclamide)","Gemfibrozil","Telmisartan"]
[null,"d","Empty","S1629","S1640","S1651","S1665","S1679","S1691","S1705","S1717","S1730","S1739","Empty"]
[{"$nulls":3},"Orlistat (Ro 18-0647)","Albendazole (SKF-62979)","Telbivudine","Estrone","Flurbiprofen","Praziquantel","Progesterone (NSC 9704)","Fomepizole","Indapamide","Thiabendazole"]
[null,"e","Empty","S1630","S1641","S1652","S1666","S1680","S1692","S1706","S1718","S1732","S1740","Empty"]
[{"$nulls":3},"Allopurinol","Chlorothiazide","Monobenzone","Flucytosine","Disulfiram (NSC 190940)","Busulfan (NSC-750)","Lamivudine (BCH-189)","Adefovir Dipivoxil (GS 0840)","Mitotane","Guaifenesin"]
[null,"f","Empty","S1631","S1643","S1653","S1667","S1681","S1693","S1709","S1719","S1733","S1741","Empty"]
[{"$nulls":3},"Allopurinol Sodium","Ursodiol","Tretinoin (NSC 122758)","Trichlormethiazide","Mesalamine (5-ASA)","Carbamazepine","Estradiol","Zalcitabine","Methylprednisolone (NSC-19987)","Rifabutin (LM427)"]
[null,"g","Empty","S1633","S1644","S1654","S1669","S1683","S1696","S1712","S1721","S1734","S1742","Empty"]
[{"$nulls":3},"Zafirlukast (ICI-204219)","Nitrofural","Phenylbutazone","Loteprednol etabonate","Ipratropium Bromide","Hydrocortisone (NSC 10483)","Deferasirox (ICL-670)","Azathioprine","Meloxicam","Nevirapine (NSC 641530)"]
[null,"h","Empty","S1635","S1645","S1655","S1673","S1685","S1701","S1713","S1723","S1735","S1743","Empty"]
[{"$nulls":3},"Erythromycin","Ketoprofen","Ezetimibe (SCH-58235)","Aminophylline","Sulfanilamide","Desonide","Piroxicam","Indomethacin (NSC-77541)","Mesna","Esomeprazole magnesium"]
[]
[]
[]
[null,"Plate layout: L3800-06"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
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[{"$nulls":3},"Nicotinic Acid","Suprofen","Thioguanine (NSC 752)","Teniposide","Ranitidine Hydrochloride","Clofibrate","Atracurium Besylate","Clemastine (HS-592) fumarate","Diltiazem HCl","Sparfloxacin"]
[null,"b","Empty","S1747","S1762","S1775","S1789","S1805","S1823","S1833","S1848","S1866","S1885","Empty"]
[{"$nulls":3},"Nimodipine","Pyrazinamide","Thiotepa","Tetrabenazine (Xenazine)","Acetylcholine Chloride","Fenoprofen Calcium","Butoconazole nitrate","Curcumin","Diphenhydramine HCl","Felodipine"]
[null,"c","Empty","S1748","S1763","S1776","S1790","S1806","S1825","S1835","S1849","S1869","S1888","Empty"]
[{"$nulls":3},"Nisoldipine","Quetiapine (ICI-204636) fumarate","Toremifene Citrate (NK 622)","Rifaximin","Acipimox","Erdosteine","Azithromycin (CP-62993)","Daidzein","Dapoxetine HCl","Deflazacort"]
[null,"d","Empty","S1750","S1764","S1777","S1791","S1807","S1827","S1836","S1854","S1876","S1890","Empty"]
[{"$nulls":3},"Octocrylene","Rifampin (NSC-113926)","Ethionamide","Bacitracin Zinc","Aciclovir (BW 248U)","Betaxolol HCl","Albendazole Oxide","Bifonazole","Valaciclovir HCl","Nizatidine"]
[null,"e","Empty","S1754","S1768","S1778","S1792","S1808","S1828","S1839","S1855","S1878","S1891","Empty"]
[{"$nulls":3},"Oxybutynin","Cefditoren Pivoxil","Trifluridine (NSC 75520)","Simvastatin (MK 733)","Nifedipine (BAY-a-1040)","Proparacaine HCl","Chloroxine","Pefloxacin Mesylate","Ganciclovir (BW 759)","Carbidopa"]
[null,"f","Empty","S1756","S1770","S1782","S1793","S1811","S1829","S1840","S1856","S1880","S1894","Empty"]
[{"$nulls":3},"Enoxacin","Sulfadiazine","Azacitidine (5-Azacytidine)","Ramipril","Amiloride (MK-870) HCl","Pranlukast","Lomustine","Metoprolol Tartrate","Roxatidine Acetate HCl","Valsartan (CGP-48933)"]
[null,"g","Empty","S1759","S1771","S1784","S1794","S1813","S1830","S1843","S1858","S1881","S1895","Empty"]
[{"$nulls":3},"Pitavastatin (NK-104) calcium","Chlorprothixene","Vidarabine","Fenofibrate (NSC-281319)","Amlodipine Besylate","Oxfendazole","Chenodeoxycholic Acid","Dienestrol","Protionamide","Dipyridamole (NSC 515776)"]
[null,"h","Empty","S1760","S1773","S1786","S1799","S1816","S1831","S1845","S1859","S1883","S1896","Empty"]
[{"$nulls":3},"Rifapentine","Oxytetracycline (Terramycin)","Verteporfin (CL 318952)","Ranolazine","Chlorpheniramine Maleate","Carvedilol","Cimetidine","Diethylstilbestrol","Idoxuridine","Hydroxyurea (NSC-32065)"]
[]
[]
[]
[null,"Plate layout: L3800-07"]
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[{"$nulls":3},"Potassium Iodide","Flutamide","Haloperidol","Menadione (NSC 4170)","Sulphadimethoxine","Aripiprazole","Lacidipine","Mirtazapine","Uridine","Dyclonine HCl"]
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[{"$nulls":3},"Tropisetron HCl","Fluvastatin (XU-62-320) Sodium","Phenindione","Metformin HCl","Rimantadine","Methscopolamine","Elvitegravir (JTK-303)","Benidipine HCl","Flunarizine 2HCl","Cyproterone Acetate"]
[null,"c","Empty","S1899","S1910","S1928","S1952","S1965","S1979","S2003","S2018","S2031","S2043","Empty"]
[{"$nulls":3},"Nicotinamide (NSC 13128)","Tioconazole","Alibendol","Methoxsalen","Primidone","Amiodarone (NSC 85442) HCl","Maraviroc (UK-427857)","ENMD-2076 L-(+)-Tartaric acid","Fenticonazole Nitrate","Memantine HCl"]
[null,"d","Empty","S1902","S1913","S1933","S1956","S1969","S1983","S2005","S2020","S2032","S2044","Empty"]
[{"$nulls":3},"Vitamin B12","Tropicamide","Triamcinolone","Miconazole Nitrate","Nefiracetam","Adenine HCl","Raltegravir (MK-0518)","Formoterol Hemifumarate","Rebamipide","Cyproheptadine HCl"]
[null,"e","Empty","S1903","S1914","S1934","S1957","S1971","S1987","S2006","S2021","S2036","S2045","Empty"]
[{"$nulls":3},"Diclofenac Sodium","Pregnenolone","Nystatin (Fungicidin)","Sulfamethizole","Nicorandil","Mometasone furoate","Pyrimethamine","Chlormezanone","Aspartame","Doxifluridine"]
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[{"$nulls":3},"Avobenzone","Sulfamethoxazole","Isoniazid","Sulbactam","Tamoxifen (ICI 46474) Citrate","Propylthiouracil","Sulindac","Ketotifen Fumarate","Candesartan Cilexetil","Pioglitazone HCl"]
[null,"g","Empty","S1905","S1916","S1940","S1959","S1973","S1990","S2011","S2025","S2038","S2051","Empty"]
[{"$nulls":3},"Amlodipine","Sulfisoxazole","Levofloxacin","Tolfenamic Acid","Cyclocytidine HCl","Capsaicin(Vanilloid)","Pramipexole 2HCl Monohydrate","Urapidil HCl","Phentolamine Mesylate","Captopril"]
[null,"h","Empty","S1907","S1917","S1941","S1960","S1974","S1992","S2015","S2028","S2040","S2052","Empty"]
[{"$nulls":3},"Metronidazole","Crystal Violet","Enalapril Maleate","Pranoprofen","Meglumine","Fluticasone propionate","Suplatast Tosylate","Diclazuril","Nimesulide","Oxytetracycline Dihydrate"]
[]
[]
[]
[null,"Plate layout: L3800-08"]
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[null,"a","Empty","S2053","S2062","S2075","S2085","S2098","S2109","S2123","S2134","S2160","S2178","Empty"]
[{"$nulls":3},"Cytidine","Tiopronin","Rosiglitazone (BRL-49653) HCl","Trimebutine","Bexarotene (LGD1069)","Imidapril HCl","Dextrose","AZD8330","Almorexant HCl","AG-14361"]
[null,"b","Empty","S2054","S2064","S2077","S2086","S2099","S2111","S2124","S2149","S2161","S2179","Empty"]
[{"$nulls":3},"Orphenadrine Citrate","Balofloxacin","Atorvastatin Calcium","Ivabradine HCl","Temocapril HCl","Lapatinib (GW-572016)","Xylose","GSK1292263","RAF265 (CHIR-265)","Gandotinib (LY2784544)"]
[null,"c","Empty","S2055","S2065","S2078","S2087","S2101","S2113","S2125","S2151","S2162","S2180","Empty"]
[{"$nulls":3},"Gimeracil","Lafutidine","Famotidine","Rivastigmine Tartrate","Gabexate Mesylate","Cisatracurium Besylate","Mestranol","Sonidegib (NVP-LDE225)","AZD1480","Ixazomib (MLN2238)"]
[null,"d","Empty","S2057","S2066","S2079","S2090","S2102","S2114","S2126","S2154","S2167","S2181","Empty"]
[{"$nulls":3},"Cyclophosphamide (NSC-26271) Monohydrate","Moxonidine","Moexipril HCl","Dexmedetomidine HCl","Rasagiline Mesylate","Dronedarone HCl","Naftopidil","Dabigatran (BIBR-1048) etexilate","Bazedoxifene (TSE-424) acetate","Ixazomib Citrate (MLN9708) Analogue"]
[null,"e","Empty","S2058","S2067","S2080","S2091","S2103","S2116","S2127","S2155","S2169","S2182","Empty"]
[{"$nulls":3},"Tolnaftate","Ozagrel HCl","Clevidipine Butyrate","Betaxolol","Naltrexone HCl","Conivaptan HCl","S-(+)-Rolipram","LY2608204","Rosuvastatin (ZD4522) calcium","SB743921 HCl"]
[null,"f","Empty","S2059","S2069","S2082","S2092","S2104","S2118","S2128","S2156","S2170","S2183","Empty"]
[{"$nulls":3},"Terazosin HCl Dihydrate","Argatroban (MCI-9038)","Adiphenine HCl","Detomidine HCl","Levosulpiride","Ibutilide Fumarate","Bazedoxifene (WAY-140424) HCl","LY2886721","Givinostat (ITF2357)","Infigratinib (BGJ398)"]
[null,"g","Empty","S2060","S2071","S2083","S2096","S2105","S2119","S2130","S2158","S2173","S2185","Empty"]
[{"$nulls":3},"Bromhexine HCl","Prulifloxacin (NM441)","Procaterol HCl","Almotriptan Malate","Pantoprazole","Probucol","Atropine sulfate monohydrate","KW-2449","Telotristat Etiprate (LX 1606 Hippurate)","Allitinib tosylate"]
[null,"h","Empty","S2061","S2072","S2084","S2097","S2108","S2120","S2131","S2159","S2177","S2187","Empty"]
[{"$nulls":3},"Lovastatin (MK-803)","Seratrodast(AA-2414)","Duloxetine HCl","Ambrisentan","Flunixin Meglumin","Arbidol HCl","Roflumilast (B9302-107)","Tebipenem Pivoxil","Dichlorphenamide","Avasimibe (CI-1011)"]
[]
[]
[]
[null,"Plate layout: L3800-09"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S2188","S2216","S2233","S2256","S2266","S2283","S2296","S2308","S2317","S2329","Empty"]
[{"$nulls":3},"Phenprocoumon","Mubritinib (TAK 165)","Esomeprazole sodium","4-Methylumbelliferone (4-MU)","Asiatic Acid","Cinchonine(LA40221)","Enoxolone","Hesperetin","L-(+)-Rhamnose Monohydrate","Naringin"]
[null,"b","Empty","S2192","S2217","S2235","S2258","S2268","S2284","S2298","S2309","S2318","S2331","Empty"]
[{"$nulls":3},"Sapitinib (AZD8931)","Irinotecan (CPT-11) HCl Trihydrate","Volasertib (BI 6727)","Esculin","Baicalein","Colchicine (NSC 757)","Fisetin","Hesperidin","Lappaconitine","Neohesperidin Dihydrochalcone (Nhdc)"]
[null,"c","Empty","S2193","S2219","S2238","S2260","S2269","S2286","S2299","S2310","S2320","S2332","Empty"]
[{"$nulls":3},"GSK461364","Momelotinib (CYT387)","Palomid 529 (P529)","Amygdalin","Baicalin (NSC-661431)","Cyclosporin A (NSC 290193)","Formononetin","Honokiol (NSC 293100)","Luteolin","Neohesperidin"]
[null,"d","Empty","S2194","S2226","S2244","S2261","S2270","S2287","S2300","S2311","S2321","S2334","Empty"]
[{"$nulls":3},"R406","Idelalisib","AR-42","Andrographolide","Bergenin","Cytisine","Ferulic Acid","Hyodeoxycholic acid (HDCA)","Magnolol","Oleanolic Acid"]
[null,"e","Empty","S2195","S2228","S2246","S2262","S2271","S2289","S2302","S2312","S2322","S2335","Empty"]
[{"$nulls":3},"Lexibulin (CYT997)","Belnacasan (VX-765)","Abiraterone Acetate (CB7630)","Apigenin (LY 080400)","Berberine chloride (NSC 646666)","Daidzin","Glycyrrhizin (NSC 167409)","Icariin","(+)-Matrine","Oridonin (NSC-250682)"]
[null,"f","Empty","S2198","S2229","S2247","S2263","S2277","S2290","S2303","S2313","S2323","S2336","Empty"]
[{"$nulls":3},"SGI-1776 free base","Eltrombopag (SB497115) Olamine","Buparlisib (BKM120)","Arbutin","Caffeic Acid","Dihydroartemisinin (DHA)","Gossypol Acetate","Indole-3-carbinol","Methyl-Hesperidin","Orotic acid (6-Carboxyuracil)"]
[null,"g","Empty","S2199","S2230","S2248","S2264","S2280","S2293","S2304","S2314","S2325","S2337","Empty"]
[{"$nulls":3},"Aliskiren Hemifumarate","Galunisertib (LY2157299)","Silmitasertib (CX-4945)","Artemether","Chlorogenic Acid","DL-Carnitine HCl","Gramine","Kaempferol (NSC 407289)","Morin Hydrate","Osthole"]
[null,"h","Empty","Empty","S2231","S2250","S2265","S2282","S2295","S2305","S2316","S2328","S2338","Empty"]
[{"$nulls":4},"Telatinib","(-)-Epigallocatechin Gallate","Artesunate (WR-256283)","Cinchonidine","Emodin","Grape Seed Extract","Kinetin","Nalidixic acid","Oxymatrine"]
[]
[]
[]
[null,"Plate layout: L3800-10"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S2339","S2351","S2366","S2379","S2388","S2399","Empty","S2443","S2457","S2470","Empty"]
[{"$nulls":3},"Paeonol","Salicin","Taxifolin (Dihydroquercetin)","Dioscin","L-carnitine","Dihydromyricetin",null,"Tolbutamide (HLS 831)","Clindamycin HCl","Fluocinolone Acetonide"]
[null,"b","Empty","S2341","S2354","S2369","S2380","S2389","S2401","S2422","S2446","S2458","S2471","Empty"]
[{"$nulls":3},"(-)-Parthenolide","Sclareol","Troxerutin","Diosmetin","Naringin Dihydrochalcone","Sodium Danshensu","Ipriflavone (Osteofix)","Levosimendan","Clonidine HCl","Gallamine Triethiodide"]
[null,"c","Empty","S2344","S2357","S2370","S2381","S2390","S2403","S2423","S2450","S2459","S2473","Empty"]
[{"$nulls":3},"Piperine","Silibinin (NSC 651520)","Ursolic Acid","D-Mannitol","Polydatin","Tetrandrine (NSC-77037)","(S)-10-Hydroxycamptothecin","Equol","Clozapine","Hexestrol"]
[null,"d","Empty","S2346","S2358","S2373","S2382","S2391","S2407","S2425","S2451","S2460","S2475","Empty"]
[{"$nulls":3},"Puerarin","Silymarin","Yohimbine HCl","Evodiamine","Quercetin (NSC 9221)","Curcumol","Apocynin (NSC 2146)","Amantadine HCl","Pramipexole","Imatinib (STI571)"]
[null,"e","Empty","S2347","S2359","S2374","S2383","S2393","Empty","S2437","S2452","S2461","S2479","Empty"]
[{"$nulls":3},"Quercetin Dihydrate","Sinomenine","5-hydroxytryptophan (5-HTP)","Gastrodin","Sorbitol",null,"Rotundine","Amfebutamone (Bupropion) HCl","Domperidone","Lincomycin HCl"]
[null,"f","Empty","S2348","S2362","S2375","S2384","S2394","S2410","S2438","S2454","S2466","S2480","Empty"]
[{"$nulls":3},"Rotenone (Barbasco)","Synephrine","Aloin","Hematoxylin","Naringenin","Paeoniflorin (NSC 178886)","Synephrine HCl","Bupivacaine HCl","Estriol","Loperamide HCl"]
[null,"g","Empty","S2349","S2364","S2376","S2386","S2396","S2411","S2439","S2455","S2467","S2481","Empty"]
[{"$nulls":3},"Rutaecarpine","Tanshinone I","Ammonium Glycyrrhizinate","Indirubin (NSC 105327)","Salidroside","Geniposide","Guanosine","Bethanechol chloride","Famciclovir","Manidipine"]
[null,"h","Empty","S2350","S2365","S2378","S2387","S2397","S2412","S2442","S2456","S2468","S2482","Empty"]
[{"$nulls":3},"Rutin","Tanshinone IIA","Butylscopolamine Bromide","Lappaconite HBr","Palmatine chloride","Genipin","Inosine","Chlorpromazine HCl","Fenbendazole","Manidipine 2HCl"]
[]
[]
[]
[null,"Plate layout: L3800-11"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S2484","S2494","S2504","S2515","S2529","S2543","S2556","S2569","S2583","S2596","Empty"]
[{"$nulls":3},"Milrinone","Olopatadine HCl","Ribavirin (ICN-1229)","Vardenafil HCl Trihydrate","Dopamine HCl","Ceftiofur HCl","Rosiglitazone (BRL 49653)","Phenylephrine (NCI-C55641) HCl","Thiamphenicol","Clindamycin palmitate HCl"]
[null,"b","Empty","S2485","S2496","S2505","S2516","S2532","S2547","S2557","S2570","S2584","S2599","Empty"]
[{"$nulls":3},"Mitoxantrone (NSC-301739) 2HCl","Ozagrel","Rosiglitazone (BRL-49653) maleate","Xylazine HCl","L-Ascorbyl 6-palmitate","Tiotropium Bromide hydrate","Terbinafine HCl","Prednisolone Acetate","Clobetasol propionate","L-Thyroxine"]
[null,"c","Empty","S2486","S2497","S2506","S2517","S2533","S2549","S2559","S2573","S2585","S2601","Empty"]
[{"$nulls":3},"Moroxydine HCl","Pancuronium dibromide","Roxithromycin","Maprotiline HCl","Ritodrine HCl","Trospium chloride","Cortisone acetate","Tetracaine HCl","Brompheniramine hydrogen maleate","Gliclazide"]
[null,"d","Empty","S2487","S2499","S2508","S2519","S2534","S2551","S2561","S2574","S2586","S2602","Empty"]
[{"$nulls":3},"Mycophenolic acid","Phenoxybenzamine HCl","Scopolamine (LSM-4015) HBr","Naphazoline HCl","Isoconazole nitrate","Sulbactam sodium","Clomifene citrate","Tetracycline HCl","Dimethyl Fumarate","Acemetacin"]
[null,"e","Empty","S2489","S2500","S2509","S2521","S2535","S2552","S2564","S2576","S2589","S2603","Empty"]
[{"$nulls":3},"Nateglinide","Propafenone HCl","Sotalol HCl","Epinephrine bitartrate","Econazole nitrate","Azelastine HCl","Cloxacillin Sodium","Xylometazoline HCl","Miglitol","Tioxolone"]
[null,"f","Empty","S2491","S2501","S2510","S2524","S2536","S2553","S2565","S2577","S2590","S2605","Empty"]
[{"$nulls":3},"Nitrendipine","Pyrantel Pamoate","Spectinomycin 2HCl","Phenytoin Sodium","Miconazole","5-Aminolevulinic acid HCl","Amoxicillin Sodium","Phenacetin","Pioglitazone (AD-4833)","Idebenone"]
[null,"g","Empty","S2492","S2502","S2511","S2525","S2537","S2554","S2566","S2579","S2593","S2606","Empty"]
[{"$nulls":3},"Novobiocin Sodium (NSC 2382)","Quinine HCl Dihydrate","Sulfadoxine","Phenytoin","Secnidazole","Daphnetin","Isoprenaline (NCI-C55630) HCl","Zidovudine","Tolvaptan","Mifepristone (RU486)"]
[null,"h","Empty","S2493","S2503","S2512","S2528","S2541","S2555","S2567","S2581","S2594","S2607","Empty"]
[{"$nulls":3},"Olanzapine","Racecadotril","Tenoxicam","Ciclopirox","Clomipramine HCl","Clarithromycin","Medroxyprogesterone acetate (NSC-26386)","Quinapril HCl","Pramiracetam","Buflomedil HCl"]
[]
[]
[]
[null,"Plate layout: L3800-12"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S2608","S2617","S2634","S2679","S2698","S2726","S2748","S2759","S2774","S2791","Empty"]
[{"$nulls":3},"Fluocinonide","TAK-733","Rebastinib (DCC-2036)","Flavopiridol (L86-8275) HCl","RS-127445","PH-797804","Anacetrapib (MK-0859)","Fimepinostat (CUDC-907)","MK-2461","Sotrastaurin (AEB071)"]
[null,"b","Empty","S2609","S2621","S2656","S2680","S2699","S2727","S2749","S2760","S2776","S2792","Empty"]
[{"$nulls":3},"Inulin","AZD5438","PF-04929113 (SNX-5422)","Ibrutinib (PCI-32765)","CH5132799","Dacomitinib (PF-00299804)","BGT226 (NVP-BGT226) maleate","Canagliflozin (JNJ 28431754)","Devimistat (CPI-613)","Torcetrapib"]
[null,"c","Empty","S2610","S2623","S2658","S2685","S2700","S2730","S2751","S2762","S2778","S2794","Empty"]
[{"$nulls":3},"Lonidamine (AF-1890)","Omecamtiv mecarbil (CK-1827452)","Omipalisib (GSK2126458)","KW-2478","Tirbanibulin","Crenolanib (CP-868596)","Milciclib (PHA-848125)","Alectinib (CH5424802)","GW842166X","Sofosbuvir (GS-7977)"]
[null,"d","Empty","S2611","S2624","S2660","S2688","S2713","S2736","S2752","S2765","S2783","S2796","Empty"]
[{"$nulls":3},"Ethisterone","OSI-027","MK-0752","R547","Geldanamycin (NSC 122750)","Fedratinib (TG101348)","HER2-Inhibitor-1","MK-2048","Vistusertib (AZD2014)","WP1066"]
[null,"e","Empty","S2612","S2625","S2664","S2693","S2718","S2738","S2753","S2768","S2784","S2797","Empty"]
[{"$nulls":3},"Ribitol","Fostamatinib (R788)","Clinofibrate","Resminostat","TAK-901","PAC-1","Tivantinib (ARQ 197)","Dinaciclib (SCH727965)","TAK-285","Lonafarnib (SCH66336)"]
[null,"f","Empty","S2613","S2626","S2665","S2694","S2719","S2740","S2754","S2770","S2787","S2799","Empty"]
[{"$nulls":3},"Clorsulon","Rabusertib (LY2603618)","Ciprofibrate","Turofexorate Isopropyl (XL335)","AMG-900","GSK1070916","Xevinapant (AT406)","MK-5108 (VX-689)","Laquinimod","Daporinad"]
[null,"g","Empty","S2614","S2631","S2667","S2695","S2721","S2741","S2755","S2772","S2789","S2801","Empty"]
[{"$nulls":3},"Arecoline HBr","URB597","Dolutegravir (GSK1349572)","Nepicastat (SYN-117) HCl","Nilvadipine","Niraparib (MK-4827)","Varlitinib","Dalcetrapib (JTT-705)","Tofacitinib (CP-690550)","AZD4547"]
[null,"h","Empty","S2615","S2633","S2673","S2696","S2722","S2743","S2757","S2773","S2790","S2803","Empty"]
[{"$nulls":3},"Noradrenaline bitartrate monohydrate","NPS-2143","Trametinib (GSK1120212)","Apitolisib (GDC-0980)","JTC-801","PF-04691502","Evofosfamide (TH-302)","SB705498","Istradefylline","Galeterone"]
[]
[]
[]
[null,"Plate layout: L3800-13"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S2807","S2823","S2864","S2890","S2914","S3005","S3022","S3033","S3047","S3062","Empty"]
[{"$nulls":3},"Dabrafenib (GSK2118436)","Tideglusib (NP031112)","IMD 0354","PF-562271","Dapivirine (TMC120)","Paroxetine HCl","Cabazitaxel (XRP6258)","Vildagliptin (LAF-237)","Otilonium Bromide","Diclofenac Potassium"]
[null,"b","Empty","S2808","S2830","S2866","S2894","S2922","S3008","S3023","S3035","S3051","S3063","Empty"]
[{"$nulls":3},"Ipatasertib (GDC-0068)","Clindamycin","U-104","SB742457","Icotinib (BPI-2009H)","Zaltoprofen","Bufexamac","Daunorubicin (RP 13057) HCl","Bosentan Hydrate","Diclofenac Diethylamine"]
[null,"c","Empty","S2809","S2840","S2868","S2900","S2925","S3012","S3024","S3036","S3052","S3066","Empty"]
[{"$nulls":3},"MPEP","Apalutamide (ARN-509)","Alogliptin (SYR-322) benzoate","Cobicistat (GS-9350)","Evacetrapib (LY2484595)","Pazopanib","Lamotrigine","Pravastatin sodium","Rupatadine Fumarate","Naloxone HCl"]
[null,"d","Empty","S2811","S2845","S2872","S2902","S2928","S3015","S3026","S3037","S3053","S3067","Empty"]
[{"$nulls":3},"Sapanisertib (MLN0128)","Semaxanib (SU5416)","GW5074","S-Ruxolitinib (INCB018424)","TAK-715","Amoxicillin","Piceatannol","Bepotastine Besilate","Azelnidipine","Chlorhexidine 2HCl"]
[null,"e","Empty","S2812","S2851","S2874","S2903","S3000","S3017","S3027","S3038","S3054","S3070","Empty"]
[{"$nulls":3},"(R)-(-)-Gossypol acetic acid","Baricitinib (INCB028050)","Camostat Mesilate","Lumiracoxib","Carbazochrome sodium sulfonate (AC-17)","Aspirin (NSC 27223)","Fenoprofen calcium hydrate","Fosaprepitant dimeglumine salt","Alverine Citrate","Piracetam"]
[null,"f","Empty","S2814","S2853","S2875","S2904","S3001","S3018","S3030","S3043","S3057","S3071","Empty"]
[{"$nulls":3},"Alpelisib (BYL719)","Carfilzomib (PR-171)","Prucalopride","PF-477736","Clevudine","Niflumic acid","Niclosamide (BAY2353)","Rofecoxib","Azilsartan Medoxomil","Vanillin"]
[null,"g","Empty","S2818","S2858","S2883","S2907","S3002","S3019","S3031","S3045","S3060","S3074","Empty"]
[{"$nulls":3},"Tacedinaline (CI994)","StemRegenin 1 (SR1)","4-Aminohippuric Acid","Pirfenidone (S-7701)","Rivaroxaban (BAY 59-7939)","Ciclopirox ethanolamine","Linagliptin (BI-1356)","Cinepazide maleate","Medetomidine HCl","Chlorthalidone"]
[null,"h","Empty","S2822","S2859","S2884","S2910","S3003","S3021","S3032","S3046","S3061","S3077","Empty"]
[{"$nulls":3},"OC000459","Golvatinib (E7050)","Acesulfame Potassium","Tempol","Prostaglandin E2 (PGE2)","Rimonabant (SR141716)","Bindarit (AF 2838)","Azilsartan","Epinephrine HCl","Tazobactam"]
[]
[]
[]
[null,"Plate layout: L3800-14"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S3078","S3106","S3129","S3147","S3161","S3176","S3189","S3208","S3612","S3627","Empty"]
[{"$nulls":3},"Beclomethasone dipropionate","Pidotimod","Trimethoprim","Entacapone","Sertaconazole nitrate","Betahistine 2HCl","Ropinirole HCl","Fexofenadine HCl","Rosmarinic acid","Tryptamine"]
[null,"b","Empty","S3079","S3113","S3130","S3149","S3162","S3178","S3193","S3212","S3615","S3635","Empty"]
[{"$nulls":3},"Atovaquone","Pyridoxine HCl","Biotin (Vitamin B7)","Estradiol valerate","Tylosin tartrate","Brinzolamide","Ticarcillin sodium","Moclobemide (Ro 111163)","Dehydrocostus Lactone","Medroxyprogesterone"]
[null,"c","Empty","S3080","S3114","S3132","S3150","S3163","S3179","S3195","S3603","S3616","S3637","Empty"]
[{"$nulls":3},"Etravirine (TMC125)","Vitamin C","Sulfamerazine","Articaine HCl","Benztropine mesylate","Carbenicillin disodium","Azlocillin sodium salt","Betulinic acid","Asiaticoside","Cefpirome sulfate"]
[null,"d","Empty","S3081","S3116","S3133","S3151","S3167","S3180","S3199","S3604","S3618","S3638","Empty"]
[{"$nulls":3},"Ulipristal Acetate (CDB 2914)","Sulfathiazole","Sulfamethazine","Gliquidone","Altrenogest","Eletriptan HBr","Reboxetine mesylate","Triptolide (PG490)","Acetylspiramycin (ASPM)","Cefamandole nafate"]
[null,"e","Empty","S3083","S3117","S3137","S3153","S3170","S3181","S3200","S3606","S3621","S3639","Empty"]
[{"$nulls":3},"Indacaterol Maleate","Oxybutynin hydrochloride","Sodium salicylate","Levalbuterol tartrate","Ampicillin sodium","Flumequine","Triflusal","Fangchinoline","Pazufloxacin mesylate","Tacrine hydrochloride hydrate"]
[null,"f","Empty","S3100","S3120","S3138","S3154","S3172","S3183","S3201","S3609","S3622","S3640","Empty"]
[{"$nulls":3},"2-Thiouracil","Doxepin HCl","Methylthiouracil","Butenafine HCl","Anagrelide HCl","Amitriptyline HCl","Trifluoperazine 2HCl","Berbamine dihydrochloride","Diammonium Glycyrrhizinate","Methoxyphenamine Hydrochloride"]
[null,"g","Empty","S3104","S3121","S3140","S3155","S3173","S3185","Empty","S3610","S3623","S3641","Empty"]
[{"$nulls":3},"Moguisteine","Ornidazole","Milnacipran HCl","Mepivacaine HCl","Antipyrine","Adrenalone HCl",null,"Cordycepin","Ceftibuten dihydrate","Osalmid"]
[null,"h","Empty","S3105","S3124","S3144","S3160","S3175","S3186","S3207","S3611","S3625","S3643","Empty"]
[{"$nulls":3},"Nadifloxacin","Dexamethasone Acetate","Darifenacin HBr","Ethynodiol diacetate","Atomoxetine HCl","Azatadine dimaleate","Iopromide","(+)-Fangchinoline","Tyramine","Amitraz"]
[]
[]
[]
[null,"Plate layout: L3800-15"]
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[null,"a","Empty","S3644","S3657","S3672","S3687","S3701","S3711","S3724","S3733","S3747","S3763","Empty"]
[{"$nulls":3},"Sulfamonomethoxine","Promestriene","Cefonicid sodium","Urea","Benactyzine hydrochloride","Carbasalate Calcium","Velpatasvir","Boceprevir","Levothyroxine sodium","Cinnamaldehyde"]
[null,"b","Empty","S3645","S3658","S3673","S3689","S3703","S3713","S3726","S3735","S3750","S3766","Empty"]
[{"$nulls":3},"Kitasamycin","O6-Benzylguanine","Sulfaphenazole","Ethidium bromide","Phenethyl alcohol","Moxidectin","Selexipag","Umeclidinium bromide","Sodium benzoate","Tanshinone IIA sulfonate sodium"]
[null,"c","Empty","S3647","S3659","S3674","S3690","S3704","S3714","S3727","S3738","S3751","S3769","Empty"]
[{"$nulls":3},"Mafenide Acetate","Fludrocortisone acetate","Levamlodipine","Pargyline hydrochloride","4-Methylbenzylidene camphor","Lifitegrast","Vilanterol Trifenate","Travoprost","Quinidine hemisulfate hydrate","Palmatine"]
[null,"d","Empty","S3648","S3663","S3675","S3692","S3705","S3716","S3728","S3739","S3754","S3772","Empty"]
[{"$nulls":3},"Amlexanox (AA-673)","Afloqualone","Umbelliferone","N-Ethylmaleimide (NEM)","Chlorobutanol","Flibanserin","Grazoprevir","Calcipotriene","4-Hydroxybenzoic acid","5-Hydroxymethylfurfural"]
[null,"e","Empty","S3653","S3666","S3676","S3693","S3706","S3719","S3729","S3741","Empty","S3773","Empty"]
[{"$nulls":3},"Spermidine trihydrochloride","Ilaprazole","Carbendazim","2,6-Dihydroxypurine","Sarpogrelate hydrochloride","Topiroxostat","Iron sucrose","Benznidazole",null,"Tyrosol"]
[null,"f","Empty","S3654","S3668","S3677","S3694","S3707","S3720","S3730","S3742","S3756","S3774","Empty"]
[{"$nulls":3},"Tauroursodeoxycholic Acid (TUDCA)","Thymopentin","Cinnamic acid","Glucosamine hydrochloride","Ethopabate","Elafibranor","Metaxalone","Cholic acid","Methyl salicylate","Dehydroandrographolide Succinate Potasium Salt"]
[null,"g","Empty","S3655","S3669","S3681","S3697","S3708","S3722","S3731","S3745","S3758","S3775","Empty"]
[{"$nulls":3},"Cefepime Dihydrochloride Monohydrate","Carmustine","Vitamin E Acetate","Mafenide hydrochloride","Sulfachloropyridazine","Isavuconazole","Tipiracil hydrochloride","Balsalazide disodium","Sinomenine hydrochloride","Ligustrazine hydrochloride"]
[null,"h","Empty","S3656","S3671","S3684","S3698","S3709","S3723","S3732","S3746","S3759","S3776","Empty"]
[{"$nulls":3},"Piribedil","Quinestrol","Methacholine chloride","Nortriptyline hydrochloride","Furagin","Ramosetron Hydrochloride","Avibactam sodium","Lumefantrine","Norcantharidin","Sophoricoside"]
[]
[]
[]
[null,"Plate layout: L3800-16"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S3779","S3797","S3811","S3842","S3854","S3872","S3893","S3909","S3926","S3950","Empty"]
[{"$nulls":3},"cis-Anethole","Helicide","Ginsenoside Re","Isoquercitrin","Tetrahydropalmatine hydrochloride","Guaiacol","Bornyl acetate","Catalpol","Forsythin","Maltitol"]
[null,"b","Empty","S3781","S3799","S3812","S3843","S3856","S3876","S3895","S3914","S3927","S3951","Empty"]
[{"$nulls":3},"Ginkgolide C","Gentisic acid","Monocrotaline","Madecassoside","Allantoin","Indigo","Sophoridine","α-Hederin","Swertiamarin","Tannic acid"]
[null,"c","Empty","S3783","S3802","S3813","S3846","S3858","S3881","S3897","S3919","S3930","S3956","Empty"]
[{"$nulls":3},"Echinacoside","Trigonelline Hydrochloride","Bakuchiol","Eupatilin","Lawsone","Scopoletin","(-)-Arctigenin","Hederacoside C","Liquiritin","Tetramethylpyrazine"]
[null,"d","Empty","S3785","S3804","S3817","S3847","S3860","S3883","S3898","S3921","S3935","S3957","Empty"]
[{"$nulls":3},"Notoginsenoside R1","Alpha-Mangostin","Harmine hydrochloride","Panaxatriol","Allicin","Protopine","Hydroxy Camptothecine","Lathyrol","Nonivamide","Gamma-Oryzanol"]
[null,"e","Empty","S3788","S3805","S3824","S3849","S3865","S3885","S3899","S3922","S3937","S3959","Empty"]
[{"$nulls":3},"Carvacrol","Stevioside","Quercitrin","D-Galactose","Taurochenodeoxycholic acid","Pyrogallol","Hederagenin","(-)-epigallocatechin","Pterostilbene","(+)-Borneol"]
[null,"f","Empty","S3791","S3807","S3826","S3850","S3866","S3887","S3901","S3923","S3941","S3960","Empty"]
[{"$nulls":3},"Succinic acid","Dehydroandrographolide","Hydroxytyrosol","Glucosamine sulfate","Galanthamine","α-L-Rhamnose monohydrate","Astragaloside IV","Ginsenoside Rg1","Pinocembrin","Higenamine hydrochloride"]
[null,"g","Empty","S3794","S3809","S3835","S3851","S3868","S3889","S3905","S3924","S3944","S3965","Empty"]
[{"$nulls":3},"Palmitic acid","Imperatorin","Loganin","Camphor","Harmine","Arteether","Iso-Steviol","Ginsenoside Rb1","Valproic acid (VPA)","Vanillyl Butyl Ether"]
[null,"h","Empty","S3796","S3810","S3839","S3853","S3870","S3892","S3907","S3925","S3945","S3966","Empty"]
[{"$nulls":3},"Rebaudioside A","Scutellarin","1-Deoxynojirimycin","Perillyl alcohol","D-Pinitol","Isopsoralen","Bulleyaconi cine A","(-)-Epicatechin gallate","L-Cycloserine","Nifuratel"]
[]
[]
[]
[null,"Plate layout: L3800-17"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S3967","S3979","S3988","S4000","S4011","S4022","S4038","S4046","S4056","S4065","Empty"]
[{"$nulls":3},"Flavone","Zinc Undecylenate","Theophylline-7-acetic acid","Pergolide Mesylate","Ampiroxicam","Probenecid","Dibucaine HCl","Estradiol Cypionate","Retapamulin","Guanabenz Acetate"]
[null,"b","Empty","S3968","S3980","Empty","S4001","S4012","S4023","S4039","S4047","S4057","S4068","Empty"]
[{"$nulls":3},"Histamine","Pyridoxine",null,"Cabozantinib malate","Desloratadine","Procaine HCl","Methazolamide","Bisacodyl","Methyclothiazide","Tinidazole"]
[null,"c","Empty","S3969","S3982","S3992","S4002","S4014","S4024","S4040","S4048","S4058","S4070","Empty"]
[{"$nulls":3},"Veratric acid","Batyl alcohol","D-(+)-Trehalose dihydrate","Sitagliptin phosphate monohydrate","Hyoscyamine","Homatropine Methylbromide","Norethindrone","Carbimazole","Ropivacaine HCl","Guanidine HCl"]
[null,"d","Empty","S3970","S3983","S3995","S4003","S4017","S4025","S4041","S4049","S4059","S4071","Empty"]
[{"$nulls":3},"Vindoline","Caryophyllene oxide","Guaiazulene","Lithocholic acid","Allylthiourea","Homatropine Bromide","Olsalazine Sodium","Valdecoxib","Sodium Nitroprusside Dihydrate","Griseofulvin"]
[null,"e","Empty","S3971","S3984","S3996","S4004","S4018","S4026","S4042","S4050","S4060","S4072","Empty"]
[{"$nulls":3},"Fusidine","Nordihydroguaiaretic acid (NDGA)","Thioctic acid","Ethambutol 2HCl","Sennoside B","Hydroxyzine 2HCl","Nafcillin Sodium","Valganciclovir HCl","Erythromycin Ethylsuccinate","Decamethonium Bromide"]
[null,"f","Empty","S3974","S3985","S3997","S4007","S4019","S4031","S4043","S4051","S4061","S4073","Empty"]
[{"$nulls":3},"(+)-Catechin hydrate","Methyl 4-hydroxybenzoate","Oxaceprol","Pentamidine isethionate","Avanafil","Aclidinium Bromide","Tetrahydrozoline HCl","Nabumetone","Levobupivacaine HCl","Sodium 4-Aminosalicylate"]
[null,"g","Empty","S3975","S3986","S3998","S4009","S4020","S4034","S4044","S4053","S4062","S4075","Empty"]
[{"$nulls":3},"Protocatechuic acid","L-Arabinose","(+)-α-Lipoic acid","Mirabegron","Sodium Picosulfate","Diphemanil Methylsulfate","Toltrazuril","Sertraline HCl","Ronidazole","Zinc Pyrithione"]
[null,"h","Empty","S3977","S3987","S3999","S4010","S4021","S4037","S4045","S4054","S4064","S4076","Empty"]
[{"$nulls":3},"(-)-Borneol","L-Tryptophan","α-santonin","Acebutolol HCl","Tolcapone","Doxapram HCl","Pheniramine Maleate","Spironolactone","Escitalopram Oxalate","Propranolol HCl"]
[]
[]
[]
[null,"Plate layout: L3800-18"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4077","S4085","S4096","S4106","S4118","S4131","S4148","S4162","S4171","S4181","Empty"]
[{"$nulls":3},"Mequinol","Levobetaxolol HCl","Droperidol","Closantel","Histamine 2HCl","Levodropropizine","Ampicillin Trihydrate","Benzethonium Chloride","Choline Chloride","Nicardipine HCl"]
[null,"b","Empty","S4078","S4086","S4098","S4107","S4119","S4135","S4149","S4163","S4172","S4182","Empty"]
[{"$nulls":3},"Mefenamic Acid","Loxapine Succinate","Halcinonide","Clofazimine","Pefloxacin Mesylate Dihydrate","Clorprenaline HCl","Amfenac Sodium Monohydrate","Doxycycline Hyclate (WC2031)","Cetylpyridinium Chloride","Nifuroxazide"]
[null,"c","Empty","S4079","S4088","S4099","S4110","S4120","S4136","S4151","S4164","S4173","S4184","Empty"]
[{"$nulls":3},"Ticagrelor","Flumethasone","Dexlansoprazole","Estradiol Benzoate","Sulconazole Nitrate","Carprofen","Penfluridol","Doxofylline","1-Hexadecanol","Penciclovir"]
[null,"d","Empty","S4080","S4089","S4100","S4111","S4122","S4138","S4152","S4165","S4175","S4185","Empty"]
[{"$nulls":3},"Triamterene","Halobetasol Propionate","Esmolol HCl","Dicloxacillin Sodium","Tilmicosin","Dropropizine","Ethamsylate","Benzydamine HCl","Sulfaguanidine","Tiratricol"]
[null,"e","Empty","S4081","S4090","S4101","S4112","S4123","S4139","S4155","S4166","S4176","S4186","Empty"]
[{"$nulls":3},"Sulfacetamide Sodium","Fenspiride HCl","Voglibose","Desvenlafaxine Succinate hydrate","Timolol Maleate","Cyclizine 2HCl","Chlorzoxazone","Chlorpropamide","Trometamol","Domiphen Bromide"]
[null,"f","Empty","S4082","S4091","S4102","S4113","S4124","S4141","S4159","S4167","S4177","S4187","Empty"]
[{"$nulls":3},"Spiramycin","Ifenprodil Tartrate","Eprosartan Mesylate","Desvenlafaxine","Tolazoline HCl","Dinitolmide","Bezafibrate","Cyromazine","Uracil","Salicylanilide"]
[null,"g","Empty","S4083","S4092","S4104","S4114","S4125","S4143","S4160","S4169","S4178","S4188","Empty"]
[{"$nulls":3},"Vitamin A Acetate","Pramoxine HCl","Diminazene Aceturate","Triclabendazole","Sodium Phenylbutyrate","Pentoxyverine Citrate","Penicillin G Sodium","Teriflunomide","Climbazole","Sasapyrine"]
[null,"h","Empty","S4084","S4095","S4105","S4116","S4128","S4147","S4161","S4170","S4179","S4189","Empty"]
[{"$nulls":3},"Lomerizine 2HCl","Difluprednate","Closantel Sodium","Isovaleramide","Troxipide","Azithromycin Dihydrate","Benzoic Acid","Coumarin","Mezlocillin Sodium","Cyclandelate"]
[]
[]
[]
[null,"Plate layout: L3800-19"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4190","S4202","S4214","S4225","S4238","S4248","S4259","S4269","S4282","S4292","Empty"]
[{"$nulls":3},"Cinchophen","Verapamil (CP-16533-1) HCl","Sucralose","Mexiletine HCl","Cepharanthine","Bromfenac Sodium","Vilazodone HCl","Vinorelbine ditartrate (KW-2307)","Nelfinavir (AG 1343) Mesylate","Diphenidol HCl"]
[null,"b","Empty","S4191","S4203","S4216","S4227","S4239","S4249","S4260","S4270","S4283","S4293","Empty"]
[{"$nulls":3},"Betamipron","Furaltadone HCl","Valnemulin HCl","Fidaxomicin","Bergapten","Flopropione","Tamibarotene","Oxiracetam","Cyclobenzaprine HCl","Promethazine HCl"]
[null,"c","Empty","S4192","S4204","S4217","S4228","S4240","S4250","S4263","S4274","S4284","S4294","Empty"]
[{"$nulls":3},"Chlorquinaldol","Isosorbide","Liothyronine Sodium","Fluorometholone Acetate","Doxylamine Succinate","Sulfamethoxypyridazine","Efaproxiral Sodium","Rotigotine","Chloroprocaine HCl","Procainamide HCl"]
[null,"d","Empty","S4195","S4206","S4219","S4229","S4242","S4253","S4264","S4277","S4285","S4295","Empty"]
[{"$nulls":3},"Broxyquinoline","Cysteamine HCl","Azaperone","Oxybuprocaine HCl","Cetrimonium Bromide (CTAB)","Epinastine HCl","Etofibrate","Bambuterol HCl","Ospemifene","Meclofenamate Sodium"]
[null,"e","Empty","S4196","S4207","S4221","S4230","S4243","S4255","S4265","S4278","S4286","S4296","Empty"]
[{"$nulls":3},"Ethacridine lactate monohydrate","Clofibric Acid","Benzbromarone","Oxaprozin","Deoxycorticosterone acetate","Quinacrine 2HCl","Nicaraven","Carteolol HCl","Anidulafungin (LY303366)","Salmeterol Xinafoate"]
[null,"f","Empty","S4197","S4208","S4222","S4231","S4244","S4256","S4266","S4279","S4288","S4297","Empty"]
[{"$nulls":3},"Bemegride","Chromocarb","Piperacillin Sodium","Pilocarpine HCl","Serotonin HCl","Buspirone HCl","Brimonidine Tartrate","Demeclocycline HCl","Chloroambucil","Mupirocin"]
[null,"g","Empty","S4200","S4210","S4223","S4235","S4246","S4257","S4267","S4280","S4289","S4299","Empty"]
[{"$nulls":3},"Tolperisone HCl","Benzocaine","Mevastatin","Phenazopyridine HCl","Tranylcypromine (2-PCPA) HCl","Alizapride HCl","Diacerein","Meclofenoxate (Centrophenoxine) HCl","Metoclopramide HCl","Dicoumarol"]
[null,"h","Empty","S4201","S4213","S4224","S4237","S4247","S4258","S4268","S4281","S4291","S4301","Empty"]
[{"$nulls":3},"Florfenicol","Dirithromycin","Erythritol","Primaquine Diphosphate","Prucalopride Succinate","Luliconazole","Flufenamic acid","Tasimelteon","Labetalol HCl","(R)-(+)-Atenolol HCl"]
[]
[]
[]
[null,"Plate layout: L3800-20"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4303","S4317","S4336","S4353","S4367","S4385","S4402","S4503","S4514","S4524","Empty"]
[{"$nulls":3},"9-Aminoacridine","Clorgyline HCl","Metaraminol Bitartrate","Terfenadine","Suxibuzone","Fosfomycin Tromethamine","Oxeladin Citrate","Calcium D-Panthotenate","Acetylleucine","2-Ethoxybenzamide"]
[null,"b","Empty","S4304","S4322","S4338","S4354","S4368","S4387","S4404","S4504","S4515","S4525","Empty"]
[{"$nulls":3},"Anisindione","Disopyramide Phosphate","Methoxamine HCl","Thiostrepton","Carbenoxolone Sodium","Bendroflumethiazide","Pasiniazid","6-Mercaptopurine (6-MP) Monohydrate","Ademetionine disulfate tosylate","Ethylparaben"]
[null,"c","Empty","S4305","S4326","S4339","S4357","S4373","S4388","S4406","S4505","S4516","S4526","Empty"]
[{"$nulls":3},"Anisotropine Methylbromide","Ethoxzolamide","Meticrane","Tacrine HCl","Dicyclomine HCl","Bentiromide","Pindolol","Vinblastine (NSC-49842) sulfate","(+)-Camphor","Fenbufen"]
[null,"d","Empty","S4307","S4330","S4343","S4358","S4375","S4389","S4414","S4506","S4517","S4527","Empty"]
[{"$nulls":3},"Auranofin","Isoetharine Mesylate","Oxethazaine","Pimozide","Mepenzolate Bromide","Bephenium Hydroxynaphthoate","Sodium 4-aminohippurate","Acetazolamide","Cefotaxime sodium","Fenofibric acid"]
[null,"e","Empty","S4308","S4331","S4344","S4361","S4376","S4391","S4415","S4507","S4518","S4528","Empty"]
[{"$nulls":3},"Benzthiazide","Meclocycline Sulfosalicylate","Oxprenolol HCl","Cinoxacin","Aceclidine HCl","Camylofin Chlorhydrate","Misoprostol","17-Hydroxyprogesterone","Chloroxylenol","Furazolidone"]
[null,"f","Empty","S4309","S4332","S4345","S4362","S4377","S4393","S4416","S4509","S4520","S4530","Empty"]
[{"$nulls":3},"Bromocriptine Mesylate","Medrysone","Pentoxifylline","Glafenine HCl","Imipramine HCl","Cephapirin Sodium","Trimipramine Maleate","4-Aminoantipyrine","2-Aminoheptane","i-Inositol"]
[null,"g","Empty","S4312","S4334","S4349","S4365","S4381","S4394","S4420","S4510","S4521","S4532","Empty"]
[{"$nulls":3},"Carbadox","Mesoridazine Besylate","Procyclidine HCl","Phthalylsulfacetamide","Proadifen HCl","Clofoctol","Mefloquine HCl","4-Aminobenzoic acid","DEET","Iopamidol"]
[null,"h","Empty","S4316","S4335","S4351","S4366","S4382","S4396","S4502","S4512","S4522","S4534","Empty"]
[{"$nulls":3},"Clopamide","Metaproterenol Sulfate","Ractopamine HCl","Pinacidil","Pyrilamine Maleate","Digoxigenin","Eltrombopag","Aceglutamide","Dehydroacetic acid","6-Acetamidohexanoic acid"]
[]
[]
[]
[null,"Plate layout: L3800-21"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4535","S4546","S4559","S4569","S4584","S4594","S4603","S4620","S4630","S4640","Empty"]
[{"$nulls":3},"Methylene Blue","Xylitol","Cloxiquine","Fluphenazine dihydrochloride","Butylparaben","Cephalothin sodium","Gallic acid","Cefuroxime sodium","Diazoxide","Lesinurad"]
[null,"b","Empty","S4536","S4547","S4561","S4570","S4585","S4595","S4604","S4622","S4631","S4641","Empty"]
[{"$nulls":3},"Nitrofurantoin","8-Hydroxyquinoline","Danthron","Halothane","Succinylsulfathiazole","Cefazolin Sodium","Levofloxacin hydrate","3,4-Diaminopyridine","Prochlorperazine dimaleate salt","Tedizolid Phosphate"]
[null,"c","Empty","S4538","S4548","S4562","S4571","S4587","S4596","S4607","S4623","S4633","S4646","Empty"]
[{"$nulls":3},"Pantoprazole sodium","Aminoguanidine hydrochloride","Dehydrocholic acid","Hexylresorcinol","Pentylenetetrazol","Cefixime","2,2′-Dihydroxy-4-methoxybenzophenone","Methylbenactyzine Bromide","Isosorbide Mononitrate","Ciclesonide"]
[null,"d","Empty","S4539","S4550","S4563","S4576","S4588","S4597","S4609","S4624","S4634","S4647","Empty"]
[{"$nulls":3},"Salicylic acid","Azelaic acid","Diatrizoic acid","Sulfabenzamide","Docusate Sodium","Lercanidipine hydrochloride","Diflunisal","5,5-Dimethyloxazolidine-2,4-dione","Sodium sulfadiazine","Cefmenoxime hydrochloride"]
[null,"e","Empty","S4541","S4552","S4564","S4577","S4589","S4599","S4610","S4625","S4635","S4648","Empty"]
[{"$nulls":3},"Triclosan","Bithionol","Diethylcarbamazine citrate","Terpin hydrate","Amodiaquine dihydrochloride dihydrate","Benzyl benzoate","Mebendazole","Alcaftadine","Cyproheptadine hydrochloride sesquihydrate","Dantrolene sodium hemiheptahydrate"]
[null,"f","Empty","S4542","S4553","S4565","S4578","S4590","S4600","S4612","S4626","S4636","S4649","Empty"]
[{"$nulls":3},"Trihexyphenidyl hydrochloride","Bronopol","Diiodohydroxyquinoline","Tyloxapol","Dithranol","Benzyl alcohol","Dapson","Ethosuximide","Teneligliptin hydrobromide","Atipamezole hydrochloride"]
[null,"g","Empty","S4543","S4556","S4566","S4581","S4591","S4601","S4618","S4628","S4637","S4650","Empty"]
[{"$nulls":3},"Trimetazidine dihydrochloride","Carzenide","DL-Panthenol","Triacetin","Nitroxoline","Clioquinol","Fenoldopam mesylate","(+/-)-Sulfinpyrazone","Prasugrel Hydrochloride","Atipamezole"]
[null,"h","Empty","S4544","S4558","S4568","S4583","S4593","S4602","S4619","S4629","S4638","S4651","Empty"]
[{"$nulls":3},"Urethane","Citiolone","Ethylvanillin","Butamben","Chlormadinone acetate","Acetohydroxamic acid","Itopride hydrochloride","Chlorotrianisene","Desogestrel","Etoricoxib"]
[]
[]
[]
[null,"Plate layout: L3800-22"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4652","S4663","S4674","S4687","S4697","S4711","S4723","S4735","S4752","S4779","Empty"]
[{"$nulls":3},"Sulisobenzone","Fusidate Sodium","Hydroxyprogesterone caproate","Rivastigmine","Saxagliptin hydrate","Esculetin","(-)Epicatechin","Salvianolic acid B","Corticosterone (NSC-9705)","Menadiol Diacetate"]
[null,"b","Empty","S4655","S4664","S4676","S4689","S4698","S4714","S4725","S4736","S4753","S4783","Empty"]
[{"$nulls":3},"Sulpiride","Molsidomine","Gluconolactone","Deoxycholic acid","Vitamin K1","(-)-Menthol","Benzenesulfonamide","Trapidil","Ganoderic acid A","Benzyl isothiocyanate"]
[null,"c","Empty","S4656","S4665","S4678","S4690","S4699","S4716","S4726","S4737","S4754","S4788","Empty"]
[{"$nulls":3},"Parecoxib","Rabeprazole sodium","Povidone iodine","Escin","Etretinate","Evans Blue","Lauric Acid","Psoralen","Betulin","L-α-Phosphatidylcholine"]
[null,"d","Empty","S4657","S4666","S4679","S4691","S4701","S4717","S4727","S4744","S4759","S4789","Empty"]
[{"$nulls":3},"Eslicarbazepine Acetate","Sivelestat sodium tetrahydrate","Terazosin HCl","Oxybenzone","2-Deoxy-D-glucose (2-DG)","Isatin","Cinnarizine","Anethole trithione","p-Coumaric Acid","5-Acetylsalicylic acid"]
[null,"e","Empty","S4658","S4667","S4682","S4692","S4706","S4718","S4728","S4748","S4761","S4792","Empty"]
[{"$nulls":3},"Hydroquinidine","Lidocaine hydrochloride","Loxoprofen","Succimer","Eugenol","Acetylcholine iodide","3,3'-Diindolylmethane","Ondansetron Hydrochloride Dihydrate","Thymoquinone","N-Acetylneuraminic acid"]
[null,"f","Empty","S4660","S4669","S4683","S4693","S4707","S4719","S4731","S4749","S4768","S4797","Empty"]
[{"$nulls":3},"Glycopyrrolate","Benzocaine hydrochloride","Sildenafil Mesylate","Guanfacine Hydrochloride","Oleic Acid","Kynurenic acid","Perphenazine","Citalopram HBr","Melibiose","Nicergoline"]
[null,"g","Empty","S4661","S4672","S4685","S4695","S4708","S4720","S4733","S4750","S4769","S4803","Empty"]
[{"$nulls":3},"Tiagabine hydrochloride","Dimenhydrinate","Efavirenz","D panthenol","Palmitoylethanolamide","Cefotaxime","Retigabine","Sulfacetamide sodium salt hydrate","L-5-Hydroxytryptophan","Thymidine (NSC 21548)"]
[null,"h","Empty","S4662","S4673","S4686","S4696","S4709","S4722","S4734","S4751","S4772","S4812","Empty"]
[{"$nulls":3},"Atazanavir","Etonogestrel","Vitamin E","CarbinoxaMine Maleate","Latanoprost","(+)-Catechin","Retigabine 2HCl","Cisapride hydrate","alpha-Asarone","Ceftizoxime"]
[]
[]
[]
[null,"Plate layout: L3800-23"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4813","S4832","S4841","S4850","S4862","S4874","S4885","S4908","S4949","S4971","Empty"]
[{"$nulls":3},"Cefuroxime axetil","Tolmetin","Laurocapram","Flucloxacillin sodium","Squalene","Cefazedone","Taurolidine","SN-38","Nonanoic acid","Buparvaquone"]
[null,"b","Empty","S4815","S4833","S4843","S4851","S4865","S4875","S4886","S4927","S4952","S4973","Empty"]
[{"$nulls":3},"L-Cysteine HCl","Cefoxitin sodium","Potassium acetate","Tafluprost","Cefetamet pivoxil hydrochloride","Cephapirin Benzathine","Menbutone","Cyclen","Fumaric acid","Iminostilbene"]
[null,"c","Empty","S4816","S4834","S4844","S4852","S4866","S4876","S4889","S4931","S4953","S4975","Empty"]
[{"$nulls":3},"Diatrizoate sodium","Propantheline bromide","Cefcapene Pivoxil Hydrochloride","Gadopentetate Dimeglumine","Nicarbazin","Robenidine Hydrochloride","Perospirone hydrochloride","Propiverine hydrochloride","Usnic acid","Fimasartan"]
[null,"d","Empty","S4817","S4835","S4845","S4853","S4867","S4877","S4890","S4932","S4956","S4976","Empty"]
[{"$nulls":3},"Atenolol","Aceclofenac","Rabeprazole","Ecabet sodium","Propacetamol hydrochloride","Eperisone hydrochloride","Bifendate","Proxyphylline","Benzamidine HCl","Sulfalene (SMPZ)"]
[null,"e","Empty","S4819","S4836","S4846","S4854","S4868","S4878","S4893","S4935","S4957","S4977","Empty"]
[{"$nulls":3},"Saccharin","Nilutamide","Meropenem Trihydrate","Bedaquiline fumarate","Xanthinol Nicotinate","Neticonazole Hydrochloride","Cytosine","Asunaprevir (BMS-650032)","Linalool","Efonidipine"]
[null,"f","Empty","S4820","S4837","S4847","S4856","S4869","S4880","S4894","S4939","S4958","S4978","Empty"]
[{"$nulls":3},"Diastase","Ibudilast","Faropenem Sodium","Iproniazid","Sulfamethoxazole sodium","Cefathiamidine","D-Glucurone","cis-Aconitic acid","Glycocholic acid","Azathramycin"]
[null,"g","Empty","S4830","S4838","S4848","S4859","S4870","S4881","S4896","S4940","S4964","S4980","Empty"]
[{"$nulls":3},"Maltose","Acotiamide hydrochloride","Dalbavancin","TriacetonaMine","Cefodizime Sodium","Calcium Dobesilate","Elagolix Sodium","Maltol","Lactobionic acid","Anamorelin"]
[null,"h","Empty","S4831","S4839","S4849","S4860","S4871","S4883","S4899","S4941","S4969","S4983","Empty"]
[{"$nulls":3},"Piperonyl butoxide","Mosapride","Levocetirizine Dihydrochloride","Indole-3-carboxylic acid","Pyridoxal 5-phosphate monohydrate","Lynestrenol","Sulfogaiacol","Farnesol","Tropine","Sorbic acid"]
[]
[]
[]
[null,"Plate layout: L3800-24"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4988","S5004","S5014","S5027","S5040","S5054","S5065","S5075","S5084","S5102","Empty"]
[{"$nulls":3},"Tiamulin fumarate","Pimecrolimus","Crisaborole (AN2728)","Mebeverine Hydrochloride","Tiamulin","Rifamycin sodium salt","Ganciclovir sodium","Acotiamide","Carbazochrome","Stachyose"]
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[{"$nulls":3},"Valpromide","Cefotiam hydrochloride","Simeprevir (TMC435)","Etofylline","Difloxacin hydrochloride","Milbemycin Oxime","Pramipexole dihydrochloride","Xipamide","Azamethiphos","Proanthocyanidins"]
[null,"c","Empty","S4994","S5006","S5016","S5030","S5042","S5056","S5067","S5077","S5086","S5106","Empty"]
[{"$nulls":3},"Methylcobalamin","Teprenone","Isoprinosine","Dihydralazine sulphate","Bevantolol hydrochloride","Dinoprost tromethamine","Losartan","Regorafenib (BAY-734506) Monohydrate","p-Anisaldehyde","Lanolin"]
[null,"d","Empty","S4996","S5007","S5017","S5032","S5043","S5058","S5069","S5078","S5091","S5108","Empty"]
[{"$nulls":3},"Tavaborole (AN-2690)","Delamanid","Oxyclozanide","Mephenesin","Benorylate","Revaprazan Hydrochloride","Dabrafenib Mesylate","Osimertinib mesylate","Geranyl acetate","Tylosin"]
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[{"$nulls":3},"Avermectin B1","Brivudine","Indobufen","Terconazole","Clonixin","Pixantrone Maleate","Mupirocin calcium","Sitagliptin","Febantel","Ademetionine"]
[null,"f","Empty","S5001","S5010","S5020","S5034","S5049","S5060","S5071","S5081","S5093","S5112","Empty"]
[{"$nulls":3},"Tofacitinib (CP-690550) Citrate","Indometacin Sodium","Tilorone dihydrochloride","Melitracen hydrochloride","Thiocolchicoside","Metadoxine","Duloxetine","Ceforanide","Rafoxanide","alpha-Arbutin"]
[null,"g","Empty","S5002","S5012","S5023","S5037","S5052","S5062","S5073","S5082","S5096","S5113","Empty"]
[{"$nulls":3},"Fingolimod (FTY720) HCl","Octenidine Dihydrochloride","Nadolol","Phenazine methosulfate","Granisetron","Daclatasvir Dihydrochloride","Donepezil","Vitamin K2","SulfadiMethoxine sodium","Propyl gallate"]
[null,"h","Empty","S5003","S5013","S5025","S5038","S5053","S5063","S5074","S5083","S5100","S5114","Empty"]
[{"$nulls":3},"Tacrolimus (FK506)","Ioversol","Efinaconazole","Valethamate Bromide","Imazalil","Trelagliptin succinate","Argatroban Monohydrate","Lentinan","Pralidoxime Iodide","Hydroquinine"]
[]
[]
[]
[null,"Plate layout: L3800-25"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S5117","S5143","S5174","S5208","S5217","S5238","S5247","S5261","S5282","S5293","Empty"]
[{"$nulls":3},"Doramectin","Citropten","Kojic acid","Ciprofloxacin hydrochloride hydrate","Arformoterol Tartrate","Solifenacin (YM905)","Selamectin","Ufenamate","Lactitol monohydrate","Nimustine Hydrochloride"]
[null,"b","Empty","S5121","S5145","S5176","S5209","S5222","S5239","S5250","S5266","S5284","S5294","Empty"]
[{"$nulls":3},"Phytol","Protoporphyrin IX","Fructose","Enoxacin Sesquihydrate","Coluracetam","Paroxetine mesylate","Darunavir","Stiripentol","Adenosine 5'-monophosphate monohydrate","Cephalotin acid"]
[null,"c","Empty","S5126","S5155","S5177","S5210","S5224","S5240","S5253","S5268","S5285","S5295","Empty"]
[{"$nulls":3},"Aleuritic Acid","Raffinose","Naproxen","Sulfamethazine Sodium Salt","Adrafinil","Lenvatinib (E7080) Mesylate","Cisapride (R 51619)","Solithromycin","RU58841","Lincomycin Hydrochloride Monohydrate"]
[null,"d","Empty","S5130","S5157","S5179","S5211","S5227","S5241","S5254","S5269","S5286","S5297","Empty"]
[{"$nulls":3},"Taurocholic acid sodium salt hydrate","Thymol","Ropivacaine Mesilate","4-Aminosalicylic acid","Erythromycin thiocyanate","Lapatinib ditosylate monohydrate","Dasatinib hydrochloride","J147","Ramatroban","Vidarabine monohydrate"]
[null,"e","Empty","S5132","S5159","S5200","S5212","S5228","S5242","S5255","S5273","S5288","S5298","Empty"]
[{"$nulls":3},"Casanthranol","Doxycycline","Diaveridine","Imidazolidinyl Urea","Minoxidil sulphate","Cediranib Maleate","Nicardipine","Canrenone","Estropipate","Amoxicillin trihydrate"]
[null,"f","Empty","S5134","S5163","S5203","S5213","S5229","S5243","S5256","S5278","S5289","S5299","Empty"]
[{"$nulls":3},"D(-)-Arabinose","7-Methoxycoumarin","Sulbutiamine","Piroctone Olamine","Isosorbide dinitrate","Ruxolitinib Phosphate","Benproperine phosphate","Tedizolid (TR-700)","Ceftezole","Tosufloxacin p-Toluenesulfonate Hydrate"]
[null,"g","Empty","S5138","S5164","S5205","S5214","S5233","S5245","S5257","S5279","S5291","S5301","Empty"]
[{"$nulls":3},"Citral","Chlorotetracycline","Nilotinib hydrochloride","Imidocarb dipropionate","Fenretinide (NSC 374551)","Raltegravir potassium","Doxapram","Fendiline hydrochloride","sulfaisodimidine","Carglumic Acid"]
[null,"h","Empty","S5141","S5167","S5206","S5215","S5234","S5246","S5258","S5281","S5292","S5302","Empty"]
[{"$nulls":3},"Pyrithioxin","Benzyl cinnamate","Benzylpenicillin potassium","Abacavir (1592U89)","Nintedanib Ethanesulfonate Salt","Entecavir","Revefenacin","Dapiprazole Hydrochloride","Diazolidinyl urea","6-Methoxy-2-naphthoic acid"]
[]
[]
[]
[null,"Plate layout: L3800-26"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
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[{"$nulls":3},"Bromisoval","Nitisinone","Vanillic acid","Regadenoson","Lactitol","Betrixaban","Chlorprothixene hydrochloride","Chloramphenicol sodium succinate","Carbaryl","Hyperoside"]
[null,"b","Empty","S5309","S5326","S5345","S5359","S5369","S5389","S5401","S5411","S5428","Empty","Empty"]
[{"$nulls":3},"Propyphenazone (4-Isopropylantipyrine)","Dolasetron","Nerolidol","Butoconazole","Ethoxyquin","Betrixaban maleate","Tegaserod Maleate","Sultamicillin","Promazine hydrochloride"]
[null,"c","Empty","S5311","S5327","S5350","S5360","S5371","S5392","S5402","S5413","S5430","S5457","Empty"]
[{"$nulls":3},"Pyridoxal phosphate","Meisoindigo","Cefpodoxime proxetil","Diflorasone","Ajmaline","Mepivacaine","Dasabuvir (ABT-333)","Ertugliflozin","Metoprolol","Curculigoside"]
[null,"d","Empty","S5312","S5328","S5351","S5361","S5372","S5393","S5403","S5414","S5435","S5458","Empty"]
[{"$nulls":3},"Urolithin A","Gamithromycin","Cefmetazole sodium","Bendazac","Methyl Aminolevulinate Hydrochloride","Cyclofenil","Ombitasvir (ABT-267)","Diflucortolone valerate","Quinacrine Dihydrochloride Dihydrate","Verbascoside"]
[null,"e","Empty","S5314","S5331","S5352","S5363","S5377","S5394","S5404","S5416","S5440","S5459","Empty"]
[{"$nulls":3},"HTHQ (1-O-Hexyl-2,3,5-trimethylhydroquinone)","Ceftezole sodium","Cefminox Sodium","Pikamilone","Dibutyl phthalate","Tizoxanide","Paritaprevir (ABT-450)","Metyrapone","Berberine Sulfate","Aucubin"]
[null,"f","Empty","S5319","S5333","S5353","S5365","S5378","S5395","S5405","S5418","S5447","S5460","Empty"]
[{"$nulls":3},"Imepitoin","Sulbenicillin Sodium","Cefpiramide sodium","Alogliptin","Dimethyl phthalate","Phenolphthalein","Propylparaben","Parecoxib Sodium","Triprolidine Hydrochloride","Vitexin-2-O-rhaMnoside"]
[null,"g","Empty","S5320","S5339","S5356","S5366","S5385","S5397","S5406","S5419","S5450","S5466","Empty"]
[{"$nulls":3},"Octinoxate","4-Allylanisole","Ceftiofur","Fipronil","Imidafenacin","Chlorhexidine","Sultamicillin Tosylate","1,4-Cineole","Sofalcone","Saikosaponin A"]
[null,"h","Empty","S5322","S5341","S5357","S5367","S5386","S5398","S5407","S5420","Empty","S5473","Empty"]
[{"$nulls":3},"Sodium gualenate","Metroprolol succinate","Safinamide","Ethyl Oleate","7-Dehydrocholesterol","Nefazodone hydrochloride","Squalane","Clindamycin alcoholate",null,"Pivmecillinam hydrochloride"]
[]
[]
[]
[null,"Plate layout: L3800-27"]
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[null,"a","Empty","S5476","S5484","S5493","S5504","S5531","S5543","S5555","S5564","S5581","S5599","Empty"]
[{"$nulls":3},"Rolapitant","Rimantadine Hydrochloride","Atropine sulfate","Ropivacaine","Doripenem","1, 10-Phenanthroline monohydrate","Pamabrom","Xylazine","Olmesartan","Sodium cholate"]
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[{"$nulls":3},"Gefarnate","Desipramine Hydrochloride","Salbutamol","2’-deoxyuridine","Erythromycin estolate","D-Ribose","(-)-Sparteine Sulfate","Triflupromazine hydrochloride","Cytarabine hydrochloride","Diphenylamine Hydrochloride"]
[null,"c","Empty","S5478","S5486","S5497","S5507","S5535","S5546","S5558","S5566","S5583","S5614","Empty"]
[{"$nulls":3},"Dantrolene sodium","Fluorometholone","Iopanoic acid","Trimebutine maleate","Moxifloxacin","Sulfacetamide","D-Pantothenate Sodium","Dapagliflozin propanediol monohydrate","Cinnamyl acetate","(+)-Longifolene"]
[null,"d","Empty","S5479","S5487","S5498","S5514","S5537","S5547","S5559","S5567","S5585","S5618","Empty"]
[{"$nulls":3},"Cloperastine hydrochloride","Cefoperazone sodium","Betahistine mesylate","Lanthanum(III) chloride heptahydrate","Tizanidine","Hydroxylammonium chloride","Tetrahydropalmatine","Trimethadione","Citronellal","Hippuric acid"]
[null,"e","Empty","S5480","S5488","S5500","S5515","S5538","S5550","S5560","S5568","S5592","S5619","Empty"]
[{"$nulls":3},"Clidinium Bromide","Fluorescein","Amodiaquine hydrochloride","Penicillin G Procaine","Tropisetron","Ethyl gallate","Midecamycin","Tocofersolan","Vitamin A","Betahistine"]
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[{"$nulls":3},"Molindone hydrochloride","Disopyramide","Hydrocortisone acetate","Salmeterol","Olprinone","Amenamevir","Ethacrynic Acid","Arachidic acid","α-Terpineol","NSI-189"]
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[{"$nulls":3},"Prilocaine hydrochloride","Lomefloxacin","Ilaprazole sodium","Acetophenone","Landiolol hydrochloride","Kasugamycin hydrochloride","2-Hydroxybenzyl alcohol","Tilmicosin phosphate","(1S)-(-)-α-Pinene","Cilastatin"]
[null,"h","Empty","S5483","S5492","S5503","S5530","S5541","S5554","S5563","S5580","S5597","S5623","Empty"]
[{"$nulls":3},"Tribenzagan Hydrochloride","Econazole","O-Acetyl-L-carnitine hydrochloride","Geraniol","Dimetridazole","Lanatoside C","Thioridazine hydrochloride","Arabic gum","(1R)-(-)-Menthyl acetate","Bedaquiline"]
[]
[]
[]
[null,"Plate layout: L3800-28"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
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[{"$nulls":3},"Ammonium lactate","Hydroxyzine pamoate","Omeprazole Sodium","Fruquintinib (HMPL-013)","Desoximetasone","Carvedilol Phosphate","Acetohexamide","Tetryzoline","Benzathine penicilline","Chlorpromazine"]
[null,"b","Empty","S5626","S5651","S5659","S5669","S5692","S5705","S5718","S5728","S5737","S5750","Empty"]
[{"$nulls":3},"Benzalkonium chloride","Dexrazoxane","Emedastine","Isoxsuprine hydrochloride","Mexenone","Raceanisodamine","Acrivastine","Delapril Hydrochloride","Diclofenac Epolamine","DL-Norepinephrine hydrochloride"]
[null,"c","Empty","S5627","S5652","S5661","S5670","S5693","S5709","S5719","S5729","S5739","S5752","Empty"]
[{"$nulls":3},"Amsacrine hydrochloride","Elbasvir","Tiaprofenic acid","Chloropyramine hydrochloride","Levomilnacipran Hydrochloride","Norgestrel","Ceftizoxime sodium","Fosfosal","Nebivolol","Abametapir"]
[null,"d","Empty","S5637","S5653","S5662","S5673","S5697","S5710","S5720","S5730","S5740","S5753","Empty"]
[{"$nulls":3},"Cefotiam Hexetil Hydrochloride","Indigo carmine","Ranitidine","Mivacurium chloride","Isopropamide Iodide","Ambroxol","Glecaprevir","Alimemazine Tartrate","Palonosetron","Setipiprant (ACT-129968)"]
[null,"e","Empty","S5638","S5654","S5663","S5679","S5698","S5713","S5722","S5732","S5741","S5754","Empty"]
[{"$nulls":3},"Cefozopran hydrochloride","Indacaterol","Minaprine dihydrochloride","Dolasetron Mesylate","Ketorolac tromethamine salt","Pravastatin","Oxantel Pamoate","Sebacic acid","Quetiapine","Baricitinib phosphate"]
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[{"$nulls":3},"Rhodamine B","Venlafaxine","Orphenadrine Hydrochloride","(-)-Verbenone","Phthalylsulfathiazole","lurasidone","Dichlorophen","Stearic acid","Deferoxamine mesylate (Ba 33112)","Methyl Stearate"]
[null,"g","Empty","S5647","S5656","S5665","S5682","S5701","S5715","Empty","S5734","S5743","S5757","Empty"]
[{"$nulls":3},"Emedastine Difumarate","Diphenylpyraline hydrochloride","Drofenine Hydrochloride","Methyl linolenate","Alvimopan dihydrate (LY246736 dihydrate)","Atorvastatin",null,"Midodrine hydrochloride","γ-Linolenic acid","Isoeugenol"]
[null,"h","Empty","S5648","S5657","S5666","S5683","S5702","S5716","S5726","S5735","S5747","S5759","Empty"]
[{"$nulls":3},"Iguratimod","Ertapenem sodium","Moxisylyte hydrochloride","Isoproterenol sulfate dihydrate","Fenipentol","Abemaciclib (LY2835219)","Triiodothyronine","Midodrine","Morantel tartrate","Methyl linoleate"]
[]
[]
[]
[null,"Plate layout: L3800-29"]
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[{"$nulls":3},"Citric acid","Sulforaphane","Vancomycin","Relugolix","Citronellyl acetate","Frovatriptan Succinate","DL-Menthol","Edrophonium chloride","Olanexidine Hydrochloride semihydrate","Bepotastine"]
[null,"b","Empty","S5762","S5776","S5787","S5811","S5830","S5854","S5869","S5901","S5925","S5943","Empty"]
[{"$nulls":3},"Methyl Oleate","Proflavine","Dronedarone","Kevetrin hydrochloride","L-Xylose","Xylometazoline","Cortisone","Canagliflozin hemihydrate","Olodaterol hydrochloride","Bromhexine"]
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[{"$nulls":3},"D-Mannose","Esmolol","Motesanib (AMG-706)","Choline Fenofibrate","L-Kynurenine","Trazodone","Trans-Tranilast","Suberohydroxamic acid","Pitolisant hydrochloride","Butenafine"]
[null,"d","Empty","S5765","S5779","S5795","S5814","S5840","S5858","S5872","S5909","S5927","S5948","Empty"]
[{"$nulls":3},"Sodium Dehydrocholate","Trimetazidine","Rasagiline","cariporide","Palifosfamide","Vilazodone","Estradiol dipropionate","Anagliptin","Proguanil","Amodiaquine"]
[null,"e","Empty","S5766","S5780","S5796","S5816","S5842","S5859","S5873","S5911","S5935","S5950","Empty"]
[{"$nulls":3},"Alfuzosin","Prazosin","Vanoxerine dihydrochloride","Pyrvinium","Cabergoline","Sancycline","Scopolamine HBr trihydrate","Bictegravir","Alvimopan","Fingolimod"]
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[{"$nulls":3},"Aliskiren","Raloxifene","Alprenolol hydrochloride","acalisib (GS-9820)","Cinitapride Hydrogen Tartrate","Lercanidipine","D-Carnitine hydrochloride","Solcitinib","Cefazolin","Cefoxitin"]
[null,"g","Empty","S5768","S5782","S5803","S5821","S5845","S5862","S5886","S5921","S5938","S5952","Empty"]
[{"$nulls":3},"Fenoterol hydrobromide","Doxazosin","Alrestatin","Linoleic acid","Chalcone","Metoclopramide","Hodostin","Cyclopentolate Hydrochloride","Benazepril","Baloxavir marboxil"]
[null,"h","Empty","S5769","S5783","S5805","S5823","S5847","S5863","S5887","S5923","S5939","S6002","Empty"]
[{"$nulls":3},"Fenoterol","Montelukast","Allopregnanolone","L-Pyroglutamic acid","Ethacrynate Sodium","Metronidazole Benzoate","Khellin","Celiprolol hydrochloride","Bendamustine (SDX105)","Disufenton sodium"]
[]
[]
[]
[null,"Plate layout: L3800-30"]
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[{"$nulls":3},"Ataluren (PTC124)","2-Naphthol","Congo Red","Pyridoxal 5′-phosphate hydrate","p-Toluenesulfonic acid monohydrate","Sodium lauryl sulfate","Ethyl pyruvate","Rutin hydrate","5-Methoxytryptamine","Salicylamide"]
[null,"b","Empty","S6005","S6041","S6067","S6118","S6189","S6221","S6249","S6272","S6335","S6405","Empty"]
[{"$nulls":3},"VX-702","Dibutyl sebacate","2,4-dichlorobenzyl alcohol","Terpinen-4-ol","Acid Yellow 36","Methyl cinnamate","Picolinic acid (PCL 016)","Glycolic acid","Ethyl maltol","Octisalate"]
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[{"$nulls":3},"Imidazole","Lactose","Doxycycline monohydrate","Maltotriose","Dimethylamine hydrochloride","Triethyl citrate","L-Lactic acid","(−)-β-Pinene","Glycerol Tri-n-octanoate","Tulobuterol hydrochloride"]
[null,"d","Empty","S6007","S6049","S6073","S6136","S6202","S6231","S6251","S6281","S6343","S6408","Empty"]
[{"$nulls":3},"Bisphenol A","(+)-(S)-Carvone","Diclofenac acid","(±)-α-Bisabolol","Butylated hydroxytoluene","Methyl nicotinate","Terephthalic acid","Sodium Thiocyanate","D-Glucuronic acid","Hexetidine"]
[null,"e","Empty","S6010","S6052","S6079","S6152","S6207","S6232","S6257","S6284","S6346","S6409","Empty"]
[{"$nulls":3},"Sodium L-lactate","Saccharin sodium salt hydrate","2-Methylhexanoic acid","Acid Red 27","Levulinic acid","Methylamine hydrochloride","N-Acetylglucosamine","Tetraethylammonium bromide","L-(+)-Arabinose","Zucapsaicin"]
[null,"f","Empty","S6011","S6053","S6104","S6172","S6210","S6233","S6258","S6288","S6400","S6410","Empty"]
[{"$nulls":3},"Acetamide","Phenylglyoxylic acid","(±)-α-Tocopherol","Brucine sulfate heptahydrate","Ethanolamine hydrochloride","Tartaric acid","1,2-Propanediol","Chlorhexidine diacetate","Glucosamine","Clemizole"]
[null,"g","Empty","S6014","S6055","S6112","S6173","S6215","S6234","S6262","S6296","S6402","S6411","Empty"]
[{"$nulls":3},"Isonicotinic acid","(S)-(−)-Limonene","Oxalacetic acid","Amylmetacresol","Phthalic acid","Pentadecanoic acid","Ammonium formate","Octanoic acid","2-Aminoethanethiol","Nimorazole"]
[null,"h","Empty","S6015","S6058","S6113","S6185","S6217","S6235","S6263","S6316","S6403","S6412","Empty"]
[{"$nulls":3},"Benzylcetyldimethylammonium chloride hydrate","β-Caryophyllene","Tridecanoic acid","Arachidonic acid","o-Toluic acid","Sodium dehydroacetate","Glycerol Tributyrate","N-Acetyl-L-tyrosine","Chloramine-T","Altiratinib"]
[]
[]
[]
[null,"Plate layout: L3800-31"]
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[null,"a","Empty","S6414","S6440","S6452","S6462","S6476","S6585","S7000","S7028","S7063","S7102","Empty"]
[{"$nulls":3},"Apilimod (STA-5326)","Halazone","Delavirdine mesylate","Amezinium (methylsulfate)","Eicosapentaenoic Acid","Triethylenetetramine Dihydrochloride","AP26113-analog (ALK-IN-1)","Duvelisib (IPI-145)","LY2090314","Berzosertib (VE-822)"]
[null,"b","Empty","S6415","S6441","S6453","S6465","S6478","S6587","S7007","S7029","S7067","S7103","Empty"]
[{"$nulls":3},"Azeliragon (TTP488)","Riboflavin Tetrabutyrate","Bicyclol","Tafamidis","Fipexide hydrochloride","Clobetasone butyrate","Binimetinib (MEK162)","AZD2461","Tepotinib (EMD 1214063)","Taselisib (GDC 0032)"]
[null,"c","Empty","S6420","S6442","S6454","S6467","S6484","S6588","S7009","S7030","S7077","S7104","Empty"]
[{"$nulls":3},"AGI 1067","Chlorphenesin","Docosahexaenoic Acid","Fosfluconazole","uridine triacetate","Methylprednisolone hemisuccinate","LCL161","RG-7112","Cilengitide trifluoroacetate","AZD1208"]
[null,"d","Empty","S6421","S6443","S6455","S6468","S6487","S6590","S7010","S7036","S7083","S7110","Empty"]
[{"$nulls":3},"Diroximel Fumarate","Chromium picolinate","Clebopride malate","Trandolapril","fluticasone furoate","Hydrocortisone butyrate","GDC-0152","XL019","Ceritinib (LDK378)","(+)-JQ1"]
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[{"$nulls":3},"Cevimeline HCl hemihydrate","Triclocarban","Glycyrrhetinic acid","Thonzylamine","Doravirine (MK-1439)","(±)-Equol","Merestinib (LY2801653)","AZD3514","GSK923295","IDO-IN-2"]
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[{"$nulls":3},"Udenafil","Carazolol","Flurbiprofen Axetil","Fluralaner","X-376","GSK2981278","Birinapant (TL32711)","Oprozomib (ONX 0912)","Zotarolimus (ABT-578)","AMG-517"]
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[{"$nulls":3},"Mequitazine","Ibuprofen piconol","Nifurtimox","Tinoridine hydrochloride","Mitapivat","Cyclothiazide","VS-5584 (SB2343)","LY2874455","PF-3758309","Tovorafenib (MLN2480)"]
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[{"$nulls":3},"Talniflumate","Apronal","Permethrin","Pinaverium bromide","Briciclib","Fursultiamine","Embelin","Tezacaftor (VX-661)","HSP990 (NVP-HSP990)","XL888"]
[]
[]
[]
[null,"Plate layout: L3800-32"]
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[{"$nulls":3},"BMS-833923","Motolimod (VTX-2337)","PF-04620110","Onvansertib (NMS-P937)","Osimertinib (AZD9291)","Birabresib (OTX015)","Triapine","Vactosertib (TEW-7197)","Darolutamide (ODM-201)","Niraparib (MK-4827) tosylate"]
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[{"$nulls":3},"LGK-974","Crenigacestat (LY3039478)","Olverembatinib dimesylate (HQP1351)","Beta-Lapachone","Rilpivirine","Aloxistatin (E64d)","Uprosertib (GSK2141795)","Lorlatinib (PF-6463922)","AT13148","Lomitapide Mesylate"]
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[{"$nulls":3},"BMS-911543","Avutometinib","BIO","Vidofludimus","BAY 87-2243","Sorafenib (BAY 43-9006)","(S)-crizotinib","Decernotinib (VX-509)","SAR125844","Cerdulatinib (PRT062070) hydrochloride"]
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[{"$nulls":3},"AZD1080","Setanaxib (GKT137831)","Idasanutlin (RG-7388)","AZD1981","Itanapraced (CHF 5074)","Ascomycin (FK520)","Trelagliptin","Pritelivir (BAY 57-1293)","Ledipasvir (GS5885)","Lomitapide"]
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[{"$nulls":3},"Marimastat (BB-2516)","Spebrutinib (CC-292)","PF-04418948","Edoxaban tosylate Monohydrate","Tasisulam","Puromycin (CL13900) 2HCl","VGX-1027","Erythromycin Cyclocarbonate","N6022","Pilaralisib (XL147)"]
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[{"$nulls":3},"Ilomastat","Opaganib (ABC294640)","Losmapimod (GW856553X)",null,"IOWH032","Ribociclib (LEE011)","Darapladib (SB-480848)","CFI-400945","Abscisic Acid (Dormin)","Voxtalisib (XL765)"]
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[{"$nulls":3},"Abemaciclib mesylate (LY2835219)","Siponimod (BAF312)","Alvelestat (AZD9668)","RG2833 (RGFP109)","AZD3965","APX-3330","Afuresertib (GSK2110183)","GDC-0623","Filgotinib (GLPG0634)","Peficitinib (ASP015K)"]
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[{"$nulls":3},"Glasdegib (PF-04449913)","Molibresib (I-BET-762)","Selinexor (KPT-330)","Apabetalone (RVX-208)","Poziotinib (HM781-36B)",null,"Entospletinib (GS-9973)","Domatinostat (4SC-202)","Tasquinimod","PND-1186 (VS-4718)"]
[]
[]
[]
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[{"$nulls":3},"Telaglenastat (CB-839)","Salirasib","AZD3839","Sunitinib (SU11248)","GSK2879552 2HCl","4-Hydroxytamoxifen (Afimoxifene)","Brilanestrant (GDC-0810)","CC-115","PX-12","Zorifertinib (AZD3759)"]
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[{"$nulls":3},"Obeticholic Acid","Ceralasertib (AZD6738)","ISO-1","Dasatinib Monohydrate","Pexmetinib (ARRY-614)","CB1954","Tenofovir Alafenamide (GS-7340)","Avadomide (CC-122)","Ozanimod (RPC1063)","Favipiravir (T-705)"]
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[{"$nulls":3},"Ruboxistaurin (LY333531) HCl","AZD8186","Gilteritinib (ASP2215)","Combretastatin A4","AT7519 HCl","Cyclo (-RGDfK)","Dibutyryl-cAMP (Bucladesine)","Epacadostat (INCB024360)","ETC-1002","Napabucasin (BBI608)"]
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[{"$nulls":3},"Zoligratinib (Debio-1347)","LY2584702 Tosylate","6-Thio-dG","Fumagillin","Afatinib (BIBW2992) Dimaleate","Endoxifen HCl","Oltipraz","Bromodeoxyuridine (BrdU)",null,"FG-2216"]
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[{"$nulls":3},"Picropodophyllin (PPP)","Verdinexor (KPT-335)","TRx0237 (LMTX) mesylate","Erlotinib (OSI-774)","Itacitinib (INCB39110)","BI-847325","Oleuropein","Y-39983 HCl","Larotrectinib (LOXO-101) sulfate","Ripasudil (K-115) hydrochloride dihydrate"]
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[{"$nulls":3},"Omaveloxolone (RTA-408)","Monomethyl auristatin E (MMAE)","Cabotegravir (GSK1265744)","Docetaxel Trihydrate","AMG319","Cyclo(RGDyK)","NVP-CGM097","Belumosudil (KD025)","TIC10 (ONC201)","Entrectinib (RXDX-101)"]
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[{"$nulls":3},"Savolitinib (AZD6094)","Eprenetapopt (APR-246)","Elacridar (GF120918)","SRT2104 (GSK2245840)","Pexidartinib (PLX3397)","Eliglustat","Onatasertib (CC 223)","Nemiralisib","PLX8394","Ricolinostat (ACY-1215)"]
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[{"$nulls":3},"Sacubitril/valsartan (LCZ696)","BLZ945","Emricasan (IDN-6556)","Iadademstat (ORY-1001) 2HCl","Nazartinib (EGF816)","Ulixertinib (BVD-523)","Xanthohumol","GSK2292767","AZD8835","GSK2636771"]
[]
[]
[]
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[{"$nulls":3},"Agerafenib (RXDX-105)","Zelavespib (PU-H71)","Riviciclib hydrochloride (P276-00)","GMX1778 (CHS828)","tirabrutinib(ONO-4059) hydrochloride","Oclacitinib maleate","CCT245737","Eganelisib (IPI-549)","LXR-623 (WAY-252623)","Stenoparib (E7449)"]
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[{"$nulls":3},"Vonoprazan Fumarate (TAK-438)","GDC-0349","Vorapaxar (MK-5348)","Resiquimod (R-848)","AMG 337","Enasidenib (AG-221)","Tomivosertib (eFT-508)","PF-06409577","Eltanexor (KPT-8602)","Troglitazone (CS-045)"]
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[{"$nulls":3},"Nirogacestat (PF-03084014)","Cobimetinib (GDC-0973)","Bardoxolone Methyl","Radotinib","Daprodustat (GSK1278863)","Ivosidenib (AG-120)","VLX1570","Miransertib (ARQ 092) HCl","Mivebresib (ABBV-075)","KPT 9274 ( ATG-019)"]
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[{"$nulls":3},"Capivasertib (AZD5363)","Venetoclax (ABT-199)","C-DIM12","Riociguat (BAY 63-2521)","Verubecestat (MK-8931) Trifluoroacetate","BAY 1217389","Selonsertib (GS-4997)","PT2385","Erdafitinib (JNJ-42756493)","TAK-063"]
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[{"$nulls":3},"Empagliflozin (BI 10773)","Macitentan (ACT 064992)","CB-5083","Sivelestat (ONO-5046)","Pimavanserin tartrate","Bitopertin","Olmutinib (BI 1482694)","Lirametostat (CPI-1205)","S49076","Citarinostat (ACY-241)"]
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[{"$nulls":3},"Tariquidar (XR9576)","ASP3026","Sotagliflozin (LX4211)","Halofuginone","BFH772","RS-1","Ossirene","Tucatinib","RRx-001","CBL0137 HCl"]
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[{"$nulls":3},"PRT062607 (P505-15) HCl","Lomeguatrib","SCH58261","ON123300","Lanabecestat (AZD3293)","MK-886","MLR-1023","BGP-15 2HCl","PF-06273340","GSK2982772"]
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[{"$nulls":3},"Apremilast (CC-10004)","Pacritinib (SB1518)","Acalabrutinib (ACP-196)","Paxalisib (GDC-0084)","umbralisib (TGR-1202)","Ponesimod","Samotolisib (LY3023414)","AZD9496","Naquotinib(ASP8273)","Fisogatinib (BLU-554)"]
[]
[]
[]
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[{"$nulls":3},"Belizatinib (TSR-011)","Tofogliflozin(CSG 452)","Sitravatinib (MGCD516)","NGP 555","PF-06840003","SNS-314 Mesylate","Verinurad (RDEA3170)","Alofanib (RPT835)","LY 3200882","GSK3179106"]
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[{"$nulls":3},"GSK2256098","Seletalisib (UCB-5857)","PRN1371","C188-9","Pemrametostat (GSK3326595)","MK-8353 (SCH900353)","Bimiralisib (PQR309)","Ripretinib (DCC-2618)","Evobrutinib (M-2951)","ABX-1431"]
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[{"$nulls":3},"GDC-0575 (ARRY-575)","IRAK4-IN-2","COTI-2","Derazantinib(ARQ-087)","Tenalisib (RP6530)","Nemtabrutinib (ARQ 531)","PLX51107","S55746","Zanubrutinib (BGB-3111)","SEL120 (SEL120-34A) hydrochloride"]
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[{"$nulls":3},"Temuterkib (LY3214996)","Verubecestat (MK-8931)","Serabelisib (TAK-117)","Vorasidenib (AG-881)","H3B-6527","INCB057643","Avitinib (AC0010)","Iberdomide (CC220)","FDL169","BAY-218"]
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[{"$nulls":3},"Ritlecitinib (PF-06651600)","Omarigliptin (MK-3102)","Repotrectinib (TPX-0005)","Sodium dichloroacetate (DCA)","Glumetinib (SCC244)","PDGFR inhibitor 1","Naporafenib (LXH254)","Adavivint (SM04690)","CC-90003","JNJ-38877618(OMO-1)"]
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[{"$nulls":3},"TAS-102","Tucidinostat (Chidamide)","Pamiparib (BGB-290)","Linrodostat (BMS-986205)","AZD1390","ABBV-744","MBQ-167","Abrocitinib (PF-04965842)","Brepocitinib (PF-06700841)","Bentamapimod (AS602801)"]
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[{"$nulls":3},"Voxelotor (GBT440)","RXDX-106 (CEP-40783)","Tirofiban Hydrochloride","Ipragliflozin (ASP1941)","Abequolixron (RGX-104)","Anlotinib (AL3818) dihydrochloride","leniolisib (CDZ 173)","Tinostamustine(EDO-S101)","PFK158","Omadacycline tosylate"]
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[{"$nulls":3},"Asciminib (ABL001)","Amcasertib (BBI503)","S 38093","Reparixin (Repertaxin)","GLPG1837","IACS-010759 (IACS-10759)","INCB054329","Lanifibranor (IVA-337)","Almonertinib (HS-10296)","Letermovir (AIC246)"]
[]
[]
[]
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[{"$nulls":3},"Malic acid","Salvianolic acid A","Catharanthine hemitartrate","Corydaline","1-Indanone","Thymine","Uridine 5'-monophosphate","Demecarium Bromide","(−)-Norepinephrine","Sapropterin Dihydrochloride"]
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[{"$nulls":3},"L-Fucose","Harringtonine","Liensinine perchlorate","3-n-Butylphathlide","D-(+)-Trehalose Anhydrous","Methyl palmitate","10-Undecenoic acid","Methenamine Hippurate","Brimonidine","Ensartinib (X-396) dihydrochloride"]
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[{"$nulls":3},"(R)-(-)-Mandelic acid","Anhydroicaritin","Aristolochic acid A","Germacrone","D-(+)-Raffinose pentahydrate","(4S)-4-Hydroxy-L-isoleucine","Undecanoic acid","Thiothixene","Tiapride Hydrochloride","Josamycin"]
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[{"$nulls":3},"2'-Deoxyguanosine monohydrate","Ingenol","Melamine","Topotecan","2'-Deoxyadenosine monohydrate","Rhynchophylline","Phensuximide","Haloperidol Decanoate","Protriptyline hydrochloride","Trifluoperazine"]
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[{"$nulls":3},"Bevirimat","Pulegone","Dipotassium glycyrrhizinate","Scopolamine","Oxalic acid","Liensinine",null,"Penbutolol Sulfate","Farrerol","(-)-Fenchone"]
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[{"$nulls":3},"Sanguinarine","Berbamine","Sinensetin","Carboprost","ADP","Yangonin","Mecamylamine Hydrochloride","Oxtriphylline","Anisodamine Hydrobromide","Vadadustat"]
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[{"$nulls":3},"Wedelolactone","Sparteine","Isofraxidin","Orcinol","Neryl acetate","Liensinine diperchlorate","Ethotoin","Valbenazine tosylate","Bepridil hydrochloride","ASP5878"]
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[{"$nulls":3},"Berberine","Ammonium Glycyrrhizate","Securinine","Octyl gallate","5,7-Dihydroxy-4-methylcoumarin","Urocanic acid","Benzonatate","Madecassic acid","Indinavir Sulfate","PD153035"]
[]
[]
[]
[null,"Plate layout: L3800-37"]
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[{"$nulls":3},"Adelmidrol","MSX-122","AMG-333","Besifovir","Pimitespib (TAS-116)","Belvarafenib (HM95573)","3-O-Acetyl-11-keto-β-boswellic acid (AKBA)","Eriodictyol","Peimine","Temocapril"]
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[{"$nulls":3},"Irosustat (BN83495)","Danirixin (GSK1325756)","Radiprodil (RGH-896)","CC-401 Hydrochloride","Talabostat (PT-100)","Mavacamten (MYK-461)","Cimifugin","Harpagoside","Fargesin","Sphingosine"]
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[{"$nulls":3},"Fosamprenavir calcium salt","Avatrombopag","AZD5069","Edonerpic maleate","Navarixin (SCH-527123)","PLX5622","Boldine","Ruscogenin","Casticin","Roquinimex"]
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[{"$nulls":3},"Ozenoxacin","Temsavir (BMS-626529)","Ciforadenant (CPI-444)","SB-756050","Selpercatinib (LOXO-292)","Ziritaxestat (GLPG1690)","Irisflorentin","Vitexin","Gelsemine","PF-04457845"]
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[{"$nulls":3},"Apraclonidine HCl","Brequinar (DUP785)","PF-06282999","Etofenamate","zipalertinib","FF-10101","Dihydrocapsaicin","Pneumocandin B0","Triptonide","Tirapazamine"]
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[{"$nulls":3},"Norethisterone Enanthate","E-4031 dihydrochloride","Darovasertib (LXS-196)","APD668","Unesbulin (PTC596)","Taletrectinib (DS-6051b)","Magnolin","Dehydroandrographolide Succinate","Fadrozole (CGS16949A)","Isopropyl myristate"]
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[{"$nulls":3},"Methylprednisolone sodium succinate","E7820","MK1064","ASP-9521","AZD7648","Homoharringtonine (CGX-635)","Morin","Homoorientin","Lasofoxifene Tartrate","CPI-1189"]
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[{"$nulls":3},"ETC-159","Belotecan (CKD-602) hydrochloride","AX-024 HCl","S1RA","Futibatinib (TAS-120)","Quillaic acid","Isorhamnetin","Dracohodin perochlorate","LTI-291","Fabomotizole hydrochloride"]
[]
[]
[]
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[{"$nulls":3},"Fexinidazole","Resmetirom (MGL-3196)","Punicalagin","Olitigaltin (TD-139)","FK-3311","o-Phenanthroline","Molnupiravir (EIDD-2801)","Balicatib","Silmitasertib (CX-4945) sodium salt","Dehydroabietic acid"]
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[{"$nulls":3},"Lerisetron","Sparsentan (PS-433540, RE-021)","Myristic Acid","Sulfatinib","ATB 346","Vorolanib","BAY 2416964","TR-14035","Isuzinaxib (APX-115 free base)","Hypericin"]
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[{"$nulls":3},"Nicotinamide Riboside Chloride","Ebselen","BI-409306","SB 4","Seclidemstat (SP-2577)","Zatolmilast (BPN14770)","Verdiperstat","Treprostinil sodium","Apilimod (STA-5326) mesylate","Rebaudioside M"]
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[{"$nulls":3},"Bardoxolone","BAY1125976","BVT 2733","Licofelone (ML3000)","TP-3654","3'-Fluoro-3'-deoxythymidine (Alovudine)","Relebactam","Astemizole","Ipragliflozin L-Proline","Cynarin"]
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[{"$nulls":3},"E7046 (ER-886406)","ODM-203","GSK-2881078","Rubitecan","Anle138b","ONO-7475","ABX464","Indibulin","Navitoclax (ABT-263)","Dimethylcurcumin (ASC-J9)"]
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[{"$nulls":3},"2-Aminoethyl Diphenylborinate (2-APB)","Firsocostat (GS-0976)","Anavex 2-73 HCl","Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222)","Mobocertinib (TAK788)","SX-682","BMS-813160","SC-43","Vindesine sulfate","Gefapixant"]
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[{"$nulls":3},"ETC-206 (AUM 001)","Dapansutrile","Pleconaril","2'-Deoxy-5-Fluorocytidine","GS-441524","ASP4132","Pemigatinib (INCB054828)","CBL0137","Brilliant Blue G","Bozitinib (PLB-1001)"]
[]
[]
[]
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[{"$nulls":3},"Miransertib (ARQ-092)","Preladenant","ABTL-0812","Ampalex (CX-516)","JNJ-42165279","Irinotecan (CPT-11)","Malonic acid","Maleimide","Bis(2-ethylhexyl) phthalate","Trypan Blue"]
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[{"$nulls":3},"Gossypol","Cenicriviroc (TAK-652)","Donafenib (Sorafenib D3)","Tirasemtiv (CK-2017357)","Namodenoson (CF-102)","XL228","Deoxycholic acid sodium salt","Pyruvic acid","N-Acetyl-D-mannosamine","DOTAP chloride"]
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[{"$nulls":3},"ONC206","BI 894999","Phenoxodiol (Haginin E)","COH-29","BNC210","GSK3117391","Maleic acid","Glutaric acid","Oxiglutatione","Dorzagliatin"]
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[{"$nulls":3},"Triazavirin","GSK3145095","Pibrentasvir (ABT-530)","Antineoplaston A10","Ticlopidine","Staurosporine (AM-2282)","Pyrazole","Amiloxate","Ceftaroline Fosamil","Lanreotide"]
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[{"$nulls":3},"Ningetinib","Mezigdomide (CC-92480)","NEO2734","Emodepside","FPL 62064","Adenine","2-Deoxy-D-ribose","Myosmine","Apatinib","Insulin (human)"]
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[{"$nulls":3},"Monomethyl Fumarate","Mitoquinone (MitoQ10) mesylate","Acelarin (NUC-1031)","Avacopan (CCX168)","O-304","NP-G2-044","N-Acetyl-L-leucine","2-Methylpentanoic acid","Hemin","β-Elemene"]
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[{"$nulls":3},"Clascoterone","Orelabrutinib (ICP-022)","Remibrutinib (LOU064)","BI-671800","Carbetapentane","DL-Tartaric acid","Pyridoxal hydrochloride","D-Mannosamine hydrochloride","Indole","Treosulfan"]
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[{"$nulls":3},"Capric acid","Elraglusib","APD597","PF-04995274","Barnidipine","Menthone","D-(-)-Tartaric acid","Palmitoleic acid","3-Hydroxybenzoic acid","Perhexiline maleate"]
[]
[]
[]
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[{"$nulls":3},"APTO-253","Saroglitazar","CB-103","Liranaftate","Brequinar Sodium","4-Phenylbutyric acid (4-PBA)","Dydrogesterone","Edoxaban","Almitrine mesylate","Trametinib DMSO solvate"]
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[{"$nulls":3},"LY-3381916","NBQX (FG9202)","Batefenterol","SCH-442416","Spermidine","Rhodamine 6G","Phenol Red sodium salt","Ertugliflozin L-pyroglutamic acid","2-Phenylacetamide","Thiamine monochloride"]
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[{"$nulls":3},"Navoximod","Desidustat","CGP71683 hydrochloride","Tecovirimat","Trotabresib","Adipic acid","Ensulizole","Ixazomib Citrate (MLN9708)","Isomalt","Delafloxacin Meglumine"]
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[{"$nulls":3},"Atamparib (RBN-2397)","Tapinarof","Canertinib dihydrochloride","Metarrestin (ML246)","Rhodamine 123","D-Gluconic acid","Emamectin Benzoate","Eliglustat hemitartrate","Neotame","Tetraethylammonium chloride"]
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[{"$nulls":3},"Ginsenoside Ro","Muramyl dipeptide","Varenicline (CP 526555) dihydrochloride","Lefamulin acetate (Xenleta)","Mebrofenin","3-Phenoxybenzoic acid","Rifamycin S","Ledipasvir acetone","Dimercaprol","Tetracycline"]
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[{"$nulls":3},"Fraxin","Fluzoparib (SHR-3162)","RP-64477","Ecamsule.2Na","Hexylene glycol","Sucrose","Sacubitril hemicalcium salt","Metamizole sodium hydrate","Pipobroman","Cetylpyridinium chloride monohydrate"]
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[{"$nulls":3},"Pentostatin","TVB-2640","Crotamiton","Monocaprylin","Bendazol","Resazurin sodium","Tenofovir alafenamide hemifumarate","Pleuromutilin","Guanabenz","Sodium nitroprusside"]
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[{"$nulls":3},"Enarodustat (JTZ-951)","TK216","Indocyanine green","Perflubron","Triolein","Pimethixene maleate","Tenofovir alafenamide fumarate","Benzophenone","Iproniazid phosphate","Quinine"]
[]
[]
[]
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[{"$nulls":3},"Maltose monohydrate","Enasidenib Mesylate","Ciprofloxacin hydrochloride","Ribociclib succinate","Promethazine","Pantoprazole sodium hydrate","Propafenone","Alverine","Tenofovir Disoproxil","Methylprednisolone Acetate"]
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[{"$nulls":3},"Iohexol","Fostamatinib disodium hexahydrate","Irinotecan hydrochloride","Lesinurad sodium","Oxytetracycline hydrochloride","Ceftriaxone Sodium","Larotrectinib","Amitriptyline","Dabigatran etexilate mesylate","S(-)-Propranolol hydrochloride"]
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[{"$nulls":3},"Homosalate","Ethacridine lactate","Neticonazole","Crizotinib hydrochloride","Allylestrenol","Amcinonide","Levocetirizine","Metoclopramide hydrochloride hydrate","Sulfathiazole sodium","Purine"]
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[{"$nulls":3},"Quinidine hydrochloride monohydrate","Regorafenib Hydrochloride","Levobupivacaine","Cinacalcet","Cefodizime","Megestrol","Beclamide","Menadione bisulfite sodium","Urapidil","Oxolamine Citrate"]
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[{"$nulls":3},"Atropine","Rucaparib","Dexamethasone palmitate","S-(+)-Ketoprofen","Trometamol hydrochloride","Pizotifen","Efonidipine hydrochloride monoethanolate","L-(-)-α-Methyldopa hydrate","Amlodipine maleate","Sodium tauroglycocholate"]
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[{"$nulls":3},"Pyrithioxin Dihydrochloride","Ceritinib dihydrochloride","Perospirone","L-Thyroxine sodium salt pentahydrate","Spectinomycin dihydrochloride pentahydrate","Ipratropium bromide monohydrate","L-Carnitine hydrochloride","Thiamine nitrate","Dicloxacillin Sodium hydrate","Eicosapentaenoic acid ethyl ester"]
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[{"$nulls":3},"Balsalazide","Oxacillin sodium","Cefpiramide","Furosemide sodium","Prednisone acetate","Norethindrone acetate","DL-Carnitine","Vardenafil hydrochloride","Pemetrexed","Amdinocillin"]
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[{"$nulls":3},"Nilotinib hydrochloride monohydrate","Procaine penicillin G","Ribociclib hydrochloride","Rucaparib Camsylate","Ceftiofur sodium","Bromfenac sodium hydrate","Bisoprolol","Metformin","Hydrocortisone hemisuccinate","Lusutrombopag"]
[]
[]
[]
[null,"Plate layout: L3800-42"]
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[{"$nulls":3},"Chloroquine (NSC-187208)","Inobrodib (CCS-1477)","Elimusertib (BAY-1895344)","BMS-986020","Levomefolic acid","Visomitin (SKQ1)","Danicamtiv (MYK-491)","Ibrolipim","Fadraciclib (CYC065)","Bradykinin"]
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[{"$nulls":3},"Fostemsavir","Vericiguat","Avexitide","Olodaterol (BI 1744)","Bavdegalutamide (ARV-110)","AG-636","Gadoteridol","Vonafexor (EYP001)","Azemiglitazone (MSDC-0602)","β-Cyclodextrin"]
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[{"$nulls":3},"Pelabresib (CPI-0610)","Lanraplenib (GS-9876)","DDD107498","(R)-(-)-Ibuprofen","Glycerol phenylbutyrate","Emavusertib (CA-4948)","Isosulfan Blue","Cyclizine","Saquinavir (Ro 31-8959)","Vodobatinib (K0706)"]
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[{"$nulls":3},"ME-401","Farudodstat","Derenofylline (SLV320)","Alpha-Estradiol","Varenicline","CC-90009","Triheptanoin","VX-150","OT-82","Pizuglanstat (TAS-205)"]
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[{"$nulls":3},"Remdesivir (GS-5734)","Indisulam","Olodanrigan (EMA401)","KL001","Iron Dextran","Danuglipron (PF-06882961)","Dipivefrin Hydrochloride","WS-12","LM11A-31","Seralutinib (GB002)"]
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[{"$nulls":3},"(Z)-4-Hydroxytamoxifen","6-Aminonicotinamide","Eprotirome (KB2115)","Cilengitide","Lucitanib (E3810) hydrochloride","MYLS22","2-Hydroxybenzylamine","Grapiprant (CJ-023,423)","JNJ-67856633","Tegoprazan"]
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[{"$nulls":3},"Amcenestrant (SAR439859)","BDTX-189","Remogliflozin etabonate (GSK189075)","Sephin-1","Inavolisib (GDC-0077)","JNJ-63576253 (TRC-253)","Olesoxime (TRO 19622)","Pamufetinib (TAS-115)","BMS-986299","Simufilam dihydrochloride"]
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[{"$nulls":3},"Puromycin aminonucleoside","Iodoacetamide","Cerdulatinib (PRT062070)","LY3405105","Revumenib","Pimonidazole","JNJ-10229570","Propidium Iodide","Imeglimin (EMD 387008) Hydrochloride","Fluorofenidone"]
[]
[]
[]
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[{"$nulls":3},"Baloxavir","Thioacetamide","Zinc acetate dihydrate","Abaloparatide (BA058)","Rimeporide","Gusacitinib (ASN-002)","AN-2718","HM43239","Deferitrin","Zapnometinib (PD0184264)"]
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[{"$nulls":3},"Gemigliptin","Hexaminolevulinate hydrochloride","Magnesium chloride","RO 5028442 (RG7713)","Ansofaxine hydrochloride","TAK-960","Deudextromethorphan (AVP-786)","Venadaparib(IDX-1197)","Raclopride","(R)-Avanafil"]
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[{"$nulls":3},"N-Nitrosodiethylamine","Phenelzine sulfate","JTE-607 Dihydrochloride","Asimadoline hydrochloride",null,"SQ109","Riamilovir","KA2507","Invert sugar","Senicapoc (ICA-17043)"]
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[{"$nulls":3},"Bexagliflozin (EGT1442)","Tazobactam Sodium","Enclomiphene Citrate","Lu-135252","Ezutromid","Fenoldopam","DLinDMA","MSDC-0602K Potassium","DL-α-tocopherol acetate","Metrizoic acid"]
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[{"$nulls":3},"Vernakalant (RSD1235) Hydrochloride","Zinc acetate","Sunvozertinib","GET-73","NP118809","Hydroxyflutamide (Hydroxyniphtholide)","Deserpidine","paquinimod","Mometasone Furoate Hydrate"]
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[{"$nulls":3},"Linalyl Acetate","Imidacloprid","Setmelanotide (RM-493)","Taprenepag","FK962","Cutamesine Dihydrochloride","Mirodenafil Dihydrochloride","Flumatinib (HH-GV-678)","Rhamnose","Norgestimate"]
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[{"$nulls":3},"Lithium Chloride","Betamethasone sodium phosphate","Aminopterin","Lotamilast (RVT-501)","(Rac)-Antineoplaston A10","Encenicline (EVP-6124) hydrochloride","Isavuconazonium sulfate","Mericitabine","DPPE fumarate","Flecainide"]
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[{"$nulls":3},"Taurocholic acid sodium salt","Hydrocortisone sodium succinate","Miglustat","YL 0919","Euquinine","Verubulin hydrochloride","Zotiraciclib","Centhaquin","Vercirnon","Metipranolol"]
[]
[]
[]
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[{"$nulls":3},"Prednicarbate","Nomegestrol Acetate","Oritavancin Diphosphate","Aficamten (CK-274)","AZD-9574","H-Leu-Leu-OMe Hydrochloride","Etelcalcetide HCl","Bemcentinib (R428)","Fenebrutinib (GDC-0853)","Deslanoside"]
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[{"$nulls":3},"Methyl methanesulfonate","Silydianin","AST-1306","ODM-207","Dotinurad","Cridanimod","Dasiglucagon","Oleandrin (PBI-05204)","Avapritinib (BLU-285)","HT-2157"]
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[{"$nulls":3},"Lodenafil","Z944","Levamlodipine Besylate","CTB","Tandospirone","Ursodeoxycholic acid sodium","Epitalon","Talazoparib (BMN 673)","Withaferin A","Nidufexor (LMB-763)"]
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[{"$nulls":3},"Cedirogant","MID-1","Mitonafide","AFN-1252","Azosemide","3,3'-Diaminobenzidine tetrahydrochloride",null,"Pinometostat (EPZ5676)","AZD4573","Asapiprant"]
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[{"$nulls":3},"Ibiglustat succinate","Timapiprant Sodium","Segesterone acetate","tetrathiomolybdate","SAR407899 hydrochloride","Hematein","Angstrom6","Encorafenib (LGX818)","Branebrutinib (BMS-986195)","Eptapirone"]
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[{"$nulls":3},"γ-Terpinene","CXD101","Rebamipide mofetil","FHD-286","α-Linolenic acid","M7583","Disitertide(P144)","Upadacitinib (ABT-494)","TAS0728","AZD-7325"]
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[{"$nulls":3},"Esaxerenone (CS-3150)","Masitinib mesylate","RO5186582","p-Nitrobenzyl mesylate","T-1101 tosylate","Carbetocin Acetate","tat-nr2b9c","AZD-5153 6-hydroxy-2-naphthoic acid","Deucravacitinib (BMS-986165)","Volinanserin"]
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[{"$nulls":3},"Gemifloxacin mesylate","Rilpivirine Hydrochloride","Upamostat (WX-671)","Kisspeptin-10 (human)","Doxorubicin","Bremelanotide Acetate","Calcifediol","BMS-986142","MAK683","Pulrodemstat (CC-90011) besylate"]
[]
[]
[]
[null,"Plate layout: L3800-45"]
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[{"$nulls":3},"Etalocib","AT-001","AV-412 free base","Iodixanol","MRX-2843","Phorbol 12-myristate 13-acetate (PMA)","Galicaftor (ABBV-2222)","Subasumstat (TAK-981)","Simurosertib","TNO155"]
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[{"$nulls":3},"SU14813","Tosedostat (CHR2797)","CarboxyaMidotriazole orotate","PBTZ169","Foxy-5","Ixabepilone (BMS-247550)","Selitrectinib (LOXO-195)","TAS4464","Mizagliflozin (KWA 0711)","SB 265610"]
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[{"$nulls":3},"Tegatrabetan (BC-2059)","RO4929097","Romidepsin",null,"Dianhydrogalactitol (VAL-083)","Lersivirine (UK-453061)","Tolinapant (ASTX660)","Elexacaftor (VX-445)","Suramin sodium salt","Valrubicin"]
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[{"$nulls":3},"Danicopan (ACH-4471)","AG-13958","Tegobuvir","PF-05175157","Pevonedistat (MLN4924)","Midostaurin (PKC412)","Pralsetinib (BLU-667)","Cintirorgon (LYC-55716)","Sotorasib (AMG510) racemate","Etrumadenant (AB928)"]
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[{"$nulls":3},"G-1","Apatinib (YN968D1) mesylate","Vicriviroc maleate","Eliprodil (SL-820715)","Resatorvid (TAK-242)","TAK-243 (MLN7243)","Imaradenant (AZD4635)","DS-1001b (DS 1001)","Camizestrant (AZD9833)","Elacestrant (RAD1901) Dihydrochloride"]
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[{"$nulls":3},"Laninamivir Octanoate","Podophyllotoxin (Podofilox)","NLX-101","NVR 3-778","Ravoxertinib (GDC-0994)","Edicotinib(JNJ-40346527)","Samuraciclib hydrochloride (ICEC0942 hydrochloride)","Adagrasib (MRTX849)","T-5224","Ropsacitinib (PF-06826647)"]
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[{"$nulls":3},"ASTX-029","9-amino-CPT (9-Aminocamptothecin)","PNPP","GSK805","Telacebec (Q203)","Zimlovisertib (PF-06650833)","LY3295668","MK-8719","PRI-724","BMS-986158"]
[]
[]
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[{"$nulls":3},"Finerenone","APG-2575 (lisaftoclax)","Antazoline Phosphate","Emvododstat (PTC299)","BAY 2666605","Vimseltinib","Afoxolaner","Phenyl acetate","1,3-BUTANEDIOL","Oxypurinol"]
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[{"$nulls":3},"Rimiducid (AP1903)","ASN007","Endovion (NS 3728)","Relacorilant","NPX800","Terevalefim","Abarelix Acetate","p-Toluic acid","Phenylethyl isothiocyanate","D-chiro-Inositol"]
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[{"$nulls":3},"Pirtobrutinib (LOXO-305)","Tolebrutinib (SAR442168)","4SC-203","VV116","CC-99282","FN-1501","CCK Octapeptide (Sincalide)","Myrcene","Testosterone acetate","Levomenol"]
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[{"$nulls":3},"Lufotrelvir (PF-07304814)","Evatanepag","Chiauranib","Ensitrelvir fumarate","Apararenone","Tafenoquine","Ganirelix acetate (Antagon)","Menthol","DL-Adrenaline Hydrochloride","Coenzyme A"]
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[{"$nulls":3},"Nirmatrelvir (PF-07321332)","Simufilam","Melengestrol Acetate","Sovilnesib","Pridopidine","RGB-286638 free base","D-JNKI-1",null,"Phenylephrine","Gallic acid (hydrate)"]
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[{"$nulls":3},"Proxalutamide (GT0918)","Dilmapimod (SB-681323)","Quinupristin","MRTX0902","Falnidamol","GSK2983559 active metabolite","Linaclotide","(±)-Naringenin","Tyramine hydrochloride","7-Ketolithocholic acid"]
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[{"$nulls":3},"KB-0742 Dihydrochloride","Parsaclisib (INCB050465)","Zn-C3","CFT7455","Paltusotine","Zabedosertib","Antide","1-Octanol","Citric acid hydrate","1-Naphthol"]
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[{"$nulls":3},"PRN1008","XL092","Bemnifosbuvir Hemisulfate (AT-527)","GDC-1971","Ginsenoside Rg3","Poseltinib","Difelikefalin","Pyrimidine","Se-Methylselenocysteine","Ethyl linoleate"]
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[]
[]
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[{"$nulls":3},"Monolaurin","Sebetralstat","MRT-2359","Levobunolol(l-Bunolol) hydrochloride","Didox","Melanin","GS-6207","garsorasib (D-1553 )","Pimicotinib","S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt"]
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[{"$nulls":3},"Evocalcet","E-7386","Taurodeoxycholic acid sodium hydrate","pemafibrate","Norepinephrine hydrochloride","Calcium chloride dihydrate","CB-5339","Lotiglipron","Itacnosertib (TP-0184)","Hexythiazox"]
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[{"$nulls":3},"Opnurasib (JDQ-443)","AZD1656","Sodium tetradecyl sulfate","iothalamate sodium","Recilisib","BAR502","Fezolinetant","Exarafenib","VX-561(CTP-656, Deutivacaftor)","Saquinavir Mesylate"]
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[{"$nulls":3},"BGB 15025","NX-2127","Naloxegol Oxalate","methylnaltrexone bromide",null,"Dobutamine HCl","PCLX-001 (DDD86481)","Opevesostat (ODM208)","Etrasimod(APD334)","Temozolomide Acid"]
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[{"$nulls":3},"DPCPX","BI 1015550","Trovafloxacin Mesylate","LY3000328","Norepinephrine tartrate","Filanesib hydrochloride","Lirafugratinib","Gamcemetinib (CC-99677)","Cirtuvivint","Clavulanic acid"]
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[{"$nulls":3},"Digitonin","Rilematovir","Clocortolone Pivalate","Dxd","Zinc sulfate heptahydrate","Olcegepant","Tinengotinib","LY2880070","Propiolactone","Infigratinib Phosphate"]
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[{"$nulls":3},"GS-4224","Fluspirilene","Laropiprant","(-)-Isoproterenol hydrochloride","Gramicidin","CA-170 (AUPM-170)","PF-07220060 (CDK4/6-IN-6)","BAY 2965501","Capadenoson","Lumateperone"]
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[{"$nulls":3},"EG-011","Tuvusertib","Sofpironium bromide","Sodium Pyruvate","L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride","AB680","ARV-766","Fialuridine","S-Nitrosoglutathione","Acetrizoic acid"]
[]
[]
[]
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[{"$nulls":3},"Cariprazine hydrochloride","Palovarotene","Eprinomectin","Minoxidil"]
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[{"$nulls":3},"TEN-010 (RG6146,Ro-6870810,(S)-JQ-35)","IK-930","Acetaminophen","Defactinib (VS-6063)"]
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[{"$nulls":3},"TAS-119","Zamaporvint (RXC004)","AG-120 (racemic)"]
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[{"$nulls":3},"RMC-4630","Tulmimetostat","Azvudine"]
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[{"$nulls":3},"Pyrilutamide(KX-826)","Bezuclastinib","Dimethindene maleate"]
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[{"$nulls":3},"Sirpiglenastat","ZEN-3694","Idarubicin HCl"]
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[]
[]
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[{"$nulls":3},"Perifosine (KRX-0401)","Biapenem","Cidofovir","Etidronate","Taurine","Neostigmine Bromide","Neomycin sulfate","Solifenacin succinate","Amikacin hydrate","Penicillin V potassium salt"]
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[{"$nulls":3},"Palbociclib (PD-0332991) HCl","Dorzolamide HCl","Ibuprofen Lysine","Tranexamic Acid","Clindamycin Phosphate","Salbutamol Sulfate","Streptomycin sulfate","Palonosetron HCl","Tripelennamine HCl","Pirenzepine dihydrochloride"]
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[{"$nulls":3},"Pemetrexed (LY-231514) disodium","Mizoribine","Palbociclib (PD0332991) Isethionate","Levamisole hydrochloride","Lisinopril dihydrate","Tobramycin","Vancomycin HCl","Miltefosine","Ibandronate sodium monohydrate","Imipenem"]
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[{"$nulls":3},"Gemcitabine (LY-188011) HCl","Polymyxin B sulphate","Alendronate sodium trihydrate","Ticlopidine HCl","Fudosteine","NAD+","L-NAME HCl","Danofloxacin Mesylate","Abacavir sulfate","Cangrelor Tetrasodium"]
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[{"$nulls":3},"Pamidronate Disodium","Teicoplanin","Cytarabine (U-19920A)","ATP disodium","Gabapentin","Methacycline HCl","Hygromycin B","Amikacin disulfate","L-Arginine HCl (L-Arg)","Acamprosate Calcium"]
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[{"$nulls":3},"Gabapentin HCl","Varenicline Tartrate (CP 526555-18)","L-Glutamine","Procarbazine HCl","Kanamycin sulfate","Lomefloxacin HCl","Zanamivir","(R)-baclofen","Thiamine HCl (Vitamin B1)","isoleucine"]
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[{"$nulls":3},"Galanthamine HBr","Ralimetinib (LY2228820) dimesylate","Gadodiamide Hydrate","D-Cycloserine","Chondroitin sulfate","Amiloride HCl dihydrate","Plerixafor (AMD3100) 8HCl","Caspofungin (MK-0991) Acetate","Cesium chloride","L-Leucine"]
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[{"$nulls":3},"Granisetron HCl","Perindopril Erbumine","Penicillamine","Sodium butyrate","Donepezil HCl","Oxacillin sodium monohydrate","Geneticin (G418 Sulfate)","Creatinine","Ceftazidime","L-Citrulline"]
[]
[]
[]
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[{"$nulls":3},"L-Theanine","Dexamethasone Sodium Phosphate","Succinylcholine Chloride Dihydrate","Sodium Gluconate","Isepamicin Sulphate","Hydroxychloroquine Sulfate (NSC 4375)","L-Ornithine hydrochloride","Danshensu","L-Threonine","Homotaurine"]
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[{"$nulls":3},"Sodium Demethylcantharidate","Colistin Sulfate","Terbutaline Sulfate","Nefopam HCl","Micafungin (FK 463) Sodium","Dihydrostreptomycin sulfate","Cefradine","Creatine phosphate disodium salt","Choline Glycerophosphate","Calcium folinate"]
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[{"$nulls":3},"L-Lysine hydrochloride","Gentamicin Sulfate","Mildronate","Paromomycin Sulfate","Amifostine trihydrate","Sisomicin sulfate","4-Aminobutyric acid (GABA)","Glycylglycine","Timonacic","D-Pantethine"]
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[{"$nulls":3},"DL-Glutamine","Netilmicin Sulfate","Eprazinone 2HCl","Ribostamycin Sulfate","Calcium Gluceptate","Eprodisate disodium","Sarcosine","VitaMin U","Fosfomycin Disodium","L-carnosine"]
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[{"$nulls":3},"L-SelenoMethionine","Bismuth Subcitrate Potassium","Amprolium HCl","Capreomycin Sulfate","Ceftazidime Pentahydrate","Pralidoxime chloride","Choline bitartrate","Glycine","Pipemidic acid","Ozagrel sodium"]
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[{"$nulls":3},"Pemirolast potassium","Tetramisole HCl","Bacitracin","Proflavine Hemisulfate","Guanethidine Sulfate","Eflornithine (MDL-71782) hydrochloride hydrate","D-(+)-Cellobiose","Manganese chloride","Methotrexate disodium","Nylidrin Hydrochloride"]
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[{"$nulls":3},"Sodium Monofluorophosphate","Clodronate Disodium","Chloroquine diphosphate","Sodium ascorbate","Tolmetin Sodium","Captisol (SBE-β-CD)","L-Glutamic acid monosodium salt","Sodium carbonate","Riboflavin phosphate sodium","Cephradine monohydrate"]
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[{"$nulls":3},"Flavoxate HCl","Histamine Phosphate","Ceftriaxone disodium salt hemi (heptahydrate)","Apramycin Sulfate","Potassium Canrenoate","Glutathione","Sodium ferulate","L(+)-Asparagine monohydrate","DL-Citrulline","Citicoline"]
[]
[]
[]
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[{"$nulls":3},"UTP Trisodium Salt","DL-Arginine","L-aspartic Acid","pentetate calcium trisodium hydrate","Scyllo-Inositol","Diquafosol Tetrasodium","L-serine","Terlipressin Acetate","Citric acid trilithium salt tetrahydrate","Vipivotide tetraxetan (PSMA-617)"]
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[{"$nulls":3},"Loxoprofen Sodium","L-Asparagine","L-methionine","Ala-Gln","Malachite green","Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium","Adenosine disodium triphosphate hydrate","Somatostatin Acetate","Hyaluronic acid","Lithium carbonate"]
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[{"$nulls":3},"Sodium succinate","Creatine","L-arginine","L-Hydroxyproline","(R)-Serine","Rilmenidine Phosphate","Bivalirudin Trifluoroacetate","GHRP-2","Latamoxef sodium","D-Alanine"]
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[{"$nulls":3},"Guanethidine Monosulfate","Ectoine","L-cysteine","Gastrodenol","(S)-Glutamic acid","Pemetrexed Disodium Hydrate","Eptifibatide Acetate","Desmopressin Acetate","Estramustine phosphate sodium","Motixafortide (BL-8040)"]
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[{"$nulls":3},"Spermine Tetrahydrochloride","L-Valine","Clodronate disodium tetrahydrate","Bendazac L-lysine","Sodium phytate hydrate","Ruxotemitide (LTX 315)","Octreotide (SMS 201-995) acetate","Angiotensin II human Acetate","Spermine","Lanreotide acetate"]
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[{"$nulls":3},"β-Alanine","L-Proline","Lodoxamide Tromethamine","Creatine monohydrate","Chlorophyllin (sodium copper salt)","TAK-659","Atosiban Acetate","Carperitide Acetate","DL-Buthionine-Sulfoximine","L-Histidine monohydrochloride monohydrate"]
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[{"$nulls":3},"Tobramycin sulfate","L-lysine","Edetate Trisodium","Thiamine pyrophosphate hydrochloride","Sugammadex (sodium)","Adaptavir (DAPTA)","Oxytocin (Syntocinon)","(6-)ε-​Aminocaproic acid","Sodium stibogluconate","Potassium sorbate"]
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[{"$nulls":3},"DL-Serine","L-Alanine","Edetate calcium disodium","Aminomalonic acid","Gadoxetate sodium","DL-Methionine","Salmon Calcitonin Acetate","Foscarnet Sodium","HEPES","Disodium 5'-inosinate monohydrate"]
[]
[]
[]
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[{"$nulls":3},"1-Methylnicotinamide chloride","Methionine","Dexamethasone phosphate disodium","Calcium chloride","Cidofovir hydrate","Fondaparinux Sodium (Org 31540)","Papain","Potassium D-gluconate"]
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[{"$nulls":3},"Teriparatide Acetate","L-Ornithine","Gatifloxacin hydrochloride","L-NMMA acetate","Framycetin sulphate",null,"Fosphenytoin (disodium)","Ammonium sulfate"]
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[{"$nulls":3},"Felypressin Acetate","Tenofovir hydrate","Kasugamycin hydrochloride hydrate","Sodium citrate","Colistin","LY2510924","Prednisolone disodium phosphate","Sodium Bicarbonate"]
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[{"$nulls":3},"LL37 (Human cathelicidin)","Gadodiamide","Sodium citrate dihydrate","Angiotensin (1-7)","Menotropin","Balixafortide (POL6326)","Cysteamine bitartrate","Potassium Chloride"]
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[{"$nulls":3},"Zoledronic acid (ZOL 446)","Varenicline Hydrochloride","Melittin","Ammonium ferric citrate","Flavin Adenine Dinucleotide Disodium","RGX-202","D-Cysteine","Trilaciclib dihydrochloride"]
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[{"$nulls":3},"Gadobutrol","Sodium Etidronate","Elamipretide (MTP-131)","Glatiramer acetate","Bicinchoninic acid disodium salt","Larazotide","L-Norleucine","Phenformin (NSC-756501) HCl"]
[null,"g","Empty","S4383","S5260","S5962","S6289","E2638","P1019","E4111","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Bekanamycin","ATP","DL-Penicillamine","Gentamicin","Tricine","Cetrorelix Acetate","Phytic acid (dodecasodium salt hydrate)"]
[null,"h","Empty","S4443","S5330","S6991","S6872","E2830","P1027","E2759","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Piperazine adipate","Amikacin Sulfate Salt","Sodium Acetate","Merbromin","Cyclocreatine","Melanotan II","L-(+)-Ergothioneine"]
[]
[]
[]
[null,"Plate layout: L3800-53"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1019","S1353","S1615","S1929","S2157","S2582","S3059","S4033","S4654","S5677","Empty"]
[{"$nulls":3},"Canertinib (CI-1033)","Ketoconazole (R 41400)","Risperidone","Irsogladine","Taladegib (LY2940680)","Trazodone HCl","Enrofloxacin","Sennoside A","Netupitant","Xanthopterin Hydrate"]
[null,"b","Empty","S1023","S1360","S1617","S1977","S2206","S2597","S3064","S4126","S4930","S5712","Empty"]
[{"$nulls":3},"Erlotinib (OSI-774) HCl","GSK1059615","Sulfapyridine","Sarafloxacin HCl","Fostamatinib (R788) disodium","Oseltamivir Phosphate","Ambroxol HCl","Retinyl (Vitamin A) Palmitate","Cetilistat","Zofenopril calcium"]
[null,"c","Empty","S1043","S1371","S1642","S1986","S2232","S2628","S3636","S4142","S5018","S5908","Empty"]
[{"$nulls":3},"Tandutinib (MLN518)","Cefoselis Sulfate","Methyldopa","Meclizine 2HCl","Ketanserin","Gedatolisib (PKI-587)","Cefadroxil hydrate","Clopidol","Mebhydrolin napadisylate","Garenoxacin"]
[null,"d","Empty","S1046","S1424","S1698","S2035","S2251","S2684","S3721","S4156","S5035","S6001","Empty"]
[{"$nulls":3},"Vandetanib (ZD6474)","Prazosin HCl","Torsemide","Epalrestat (ONO-2235)","(-)-Huperzine A (HupA)","Pidnarulex (CX-5461)","Bilastine","Chlortetracycline HCl (NSC 13252)","6-Aminopenicillanic acid","pomaglumetad (LY404039)"]
[null,"e","Empty","S1112","S1463","S1707","S2047","S2292","S2735","S3770","S4218","S5232","S6632","Empty"]
[{"$nulls":3},"SGX-523","Ofloxacin","Eplerenone (CGP 30083)","Lornoxicam","Diosmin","MK-8776 (SCH 900776)","Sodium Aescinate","Amoxapine","Alectinib (CH5424802) hydrochloride","Mirogabalin (DS-5565)"]
[null,"f","Empty","S1211","S1464","S1724","S2110","S2424","S2788","S3801","S4262","S5272","S6642","Empty"]
[{"$nulls":3},"Imiquimod (R-837)","Marbofloxacin","Paliperidone","Vinpocetine","Hypoxanthine","Capmatinib (INCB28060)","Sodium Houttuyfonate","Ebastine","Toceranib phosphate","Branaplam (LMI070)"]
[null,"g","Empty","S1288","S1507","S1837","S2150","S2476","S2920","S3821","S4605","S5499","S7061","Empty"]
[{"$nulls":3},"Camptothecin (NSC-100880)","Irbesartan","Flubendazole","Neratinib (HKI-272)","Itraconazole (R 51211)","Mozavaptan","Nuciferine","Folic acid","Amantadine","GSK126"]
[null,"h","Empty","S1327","S1509","S1851","S2152","S2530","S3041","S3891","S4642","S5601","S7128","Empty"]
[{"$nulls":3},"Ellagic acid","Norfloxacin","Oxibendazole","Sitafloxacin Hydrate","7-Aminocephalosporanic acid","Droxidopa","Vincamine","Dolutegravir Sodium","Balofloxacin Dihydrate","Tazemetostat (EPZ-6438)"]
[]
[]
[]
[null,"Plate layout: L3800-54"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S7221","S8548","S0063","S3570","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Vesatolimod (GS-9620)","Roblitinib (FGF401)","RG3039","ARRY-382"]
[null,"b","Empty","S7518","S8568","S6949","S6385","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Voreloxin (SNS-595) hydrochloride","G1T38","OTX008","Prexasertib (LY2606368)"]
[null,"c","Empty","Empty","S8724","S4482","S9464","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":4},"Lazertinib","Palbociclib","Tranylcypromine Sulfate"]
[null,"d","Empty","S7756","S5098","S5799","S9872","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Indoximod (NLG-8189）","Gefitinib hydrochloride","Potassium guaiacolsulfonate hemihydrate","AG-270"]
[null,"e","Empty","S7842","S8927","E0161","E4160","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"LY3009120","GSK2983559 (compound 3)","Bictegravir Sodium","Glycyl-L-tyrosine"]
[null,"f","Empty","S7846","S5031","E0524","E4468","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Dubermatinib(TP-0903)","Sulfaquinoxaline sodium","Spinosad","Cabotegravir Sodium"]
[null,"g","Empty","S8138","S1502","S3309","S2544","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Molidustat (BAY 85-3934)","Cephalexin","Solasodine","Cefprozil hydrate"]
[null,"h","Empty","S8229","S8875","S7178","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Brigatinib (AP26113)","MKC8866","Prexasertib HCl (LY2606368)"]
[]
[]
[]
[null,"Plate layout: L3800-55"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S1346","S4067","S2095","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Heparin sodium","Deferiprone","Fosinopril Sodium"]
[null,"b","Empty","S1428","S4153","S2050","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Risedronate Sodium","D-Phenylalanine","Strontium Ranelate"]
[null,"c","Empty","S1911","S4226","S5264","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Disodium Cromoglycate","Minocycline (CL 59806) HCl","L-5-Methyltetrahydrofolate calcium"]
[null,"d","Empty","S1982","S4694","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Adenine sulfate","Alosetron Hydrochloride"]
[null,"e","Empty","S2106","S5355","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Azasetron HCl","Piperaquine phosphate"]
[null,"f","Empty","S2562","S5695","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Hydralazine HCl","Icatibant Acetate"]
[null,"g","Empty","S3055","S8030","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Besifloxacin HCl","Plerixafor (AMD3100)"]
[null,"h","Empty","S3749","S5650","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Calcium gluconate monohydrate","Sodium Hyaluronate"]
[]
[]
[]
[null,"Plate layout: L3800-56"]
[null,null,1,2,3,4,5,6,7,8,9,10,11,12]
[null,"a","Empty","S4444","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Hypromellose"]
[null,"b","Empty","S3505","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[{"$nulls":3},"Polidocanol"]
[null,"c","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"d","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"e","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"f","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"g","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]
[]
[null,"h","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty","Empty"]

{"sheet":"L3800-FDA & Phase I-4200 cpds","index":1,"n_rows":4201,"n_cols":26,"rows_kept":2250,"cut":true,"bounds":{"rows_first":1000,"rows_last":250,"rows_between":1000,"halvings":1}}
["Cat","Name","Plate Location","Rack Number","Formulation","Status","Pharmacopoeia","Clinical phase","Target","Pathway","Information","M.w.","CAS Number","DMSO (mg/mL)Max Solubility","DMSO (mM)Max Solubility","Water (mg/mL)Max Solubility","Water (mM)Max Solubility","URL","Formula","Form","Synonyms","SMILES","ALogP","HBA_Count","HBD_Count","RotatableBond"]
["S1003","Linifanib (ABT-869)","a2","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","Apoptosis related,Autophagy,CSF-1R,FLT3,PDGFR,VEGFR","Protein Tyrosine Kinase","Linifanib (ABT-869, AL39324, RG3635) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR, CSF-1R, Flt-1/3 and PDGFRβ with IC50 of 4 nM, 3 nM, 3 nM/4 nM and 66 nM respectively, mostly effective in mutant kinase-dependent cancer cells (i.e. FLT3). Linifanib (ABT-869) induces autophagy and apoptosis. Phase 3.",375.41,"796967-16-3",{"v":75,"d":"75.00"},199.78,"<1","N/A","http://selleckchem.com/products/ABT-869.html","C21H18FN5O","free base","AL39324,RG3635","CC1=CC(=C(F)C=C1)NC(=O)NC2=CC=C(C=C2)C3=C4C(=N[NH]C4=CC=C3)N",4.169,2,4,3]
["S1004","Veliparib (ABT-888)","b2","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","Apoptosis related,Autophagy,PARP","DNA Damage/DNA Repair","Veliparib (ABT-888, NSC 737664) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2. Veliparib increases autophagy and apoptosis. Phase 3.",244.29,"912444-00-9",{"v":17,"d":"17.00"},69.59,"<1","N/A","http://selleckchem.com/products/ABT-888.html","C13H16N4O","free base","NSC 737664","CC1(CCCN1)C2=NC3=C(C=CC=C3[NH]2)C(N)=O",0.986,2,3,2]
["S1005","Axitinib (AG 013736)","c2","L3800-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","c-Kit,PDGFR,VEGFR","Protein Tyrosine Kinase","Axitinib (AG 013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively.",386.47,"319460-85-0",{"v":35,"d":"35.00"},90.56,"<1","N/A","http://selleckchem.com/products/Axitinib.html","C22H18N4OS","free base","AG 013736","CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=N[NH]3)\\C=C\\C4=CC=CC=N4",4.492,3,2,5]
["S1006","Saracatinib (AZD0530)","d2","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","Autophagy,EGFR,Src","Angiogenesis","Saracatinib (AZD0530) is a potent Src inhibitor with IC50 of 2.7 nM in cell-free assays, and potent to c-Yes, Fyn, Lyn, Blk, Fgr and Lck; less active for Abl and EGFR (L858R and L861Q). Saracatinib induces autophagy. Phase 2/3.",542.03,"379231-04-6",{"v":35,"d":"35.00"},64.57,"<1","N/A","http://selleckchem.com/products/AZD0530.html","C27H32ClN5O5","free base","N/A","CN1CCN(CCOC2=CC(=C3C(=NC=NC3=C2)NC4=C(Cl)C=CC5=C4OCO5)OC6CCOCC6)CC1",3.814,7,1,8]
["S1007","Roxadustat (FG-4592)","e2","L3800-01","in 10mM DMSO","CFDA","N/A","Registered","Ferroptosis,HIF","Angiogenesis","Roxadustat (FG-4592) is an HIF-α prolyl hydroxylase inhibitor in a cell-free assay, stabilizes HIF-2 and induces EPO production. Roxadustat potentiates RSL3 induced ferroptosis. Phase 3.",352.34,"808118-40-3",{"v":70,"d":"70.00"},198.67,"<1","N/A","http://selleckchem.com/products/fg-4592.html","C19H16N2O5","free base","ASP1517","CC1=NC(=C(O)C2=C1C=C(OC3=CC=CC=C3)C=C2)C(=O)NCC(O)=O",2.306,4,2,5]
["S1008","Selumetinib (AZD6244)","f2","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,MEK","MAPK","Selumetinib (AZD6244, ARRY-142886) is a potent, highly selective MEK inhibitor with IC50 of 14 nM for MEK1 and Kd value of 530 nM for MEK2. It  also inhibits ERK1/2 phosphorylation with IC50 of 10 nM, no inhibition to p38α, MKK6, EGFR, ErbB2, ERK2, B-Raf, etc. Selumetinib suppresses cell proliferation, migration and trigger apoptosis. Phase 3.",457.68,"606143-52-6",{"v":91,"d":"91.00"},198.83,"<1","N/A","http://selleckchem.com/products/AZD6244.html","C17H15BrClFN4O3","free base","ARRY-142886","C[N]1C=NC2=C(F)C(=C(C=C12)C(=O)NOCCO)NC3=CC=C(Br)C=C3Cl",3.234,3,3,6]
["S1010","Nintedanib (BIBF 1120)","g2","L3800-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","FGFR,PDGFR,Src,VEGFR","Protein Tyrosine Kinase","Nintedanib (BIBF 1120, Intedanib, Vargatef, Ofev) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM in cell-free assays. Phase 3.",539.62,"656247-17-5",{"v":6,"d":"6.00"},11.12,"<1","N/A","http://selleckchem.com/products/BIBF1120.html","C31H33N5O4","free base","Intedanib, Vargatef, Ofev","COC(=O)C1=CC=C\\2C(=C1)NC(=O)C2=C(NC3=CC=C(C=C3)N(C)C(=O)CN4CCN(C)CC4)/C5=CC=CC=C5",2.965,4,2,8]
["S1011","Afatinib (BIBW2992)","h2","L3800-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Autophagy,EGFR,HER2","Protein Tyrosine Kinase","Afatinib (BIBW2992) inhibits EGFR/ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively. Afatinib induces autophagy.",485.94,"850140-72-6",{"v":97,"d":"97.00"},199.61,"<1","N/A","http://selleckchem.com/products/BIBW2992.html","C24H25ClFN5O3","Free Base","BIBW2992","CN(C)C/C=C/C(=O)NC1=CC2=C(NC3=CC=C(F)C(=C3)Cl)N=CN=C2C=C1OC4CCOC4",3.917,5,2,8]
["S1013","Bortezomib (PS-341)","a3","L3800-01","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","USP;Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,Cathepsin B,Cysteine Protease,ERK,NF-κB,Proteasome","Proteases","Bortezomib (PS-341, Velcade, LDP-341, MLM341, NSC 681239) is a potent 20S proteasome inhibitor with Ki of 0.6 nM. It exhibits favorable selectivity towards tumor cells over normal cells. Bortezomib (PS-341) inhibits NF-κB and induces ERK phosphorylation to suppress cathepsin B and inhibit the catalytic process of autophagy in ovarian cancer and other solid tumors.",384.24,"179324-69-7",{"v":76,"d":"76.00"},197.79,"<1","N/A","http://selleckchem.com/products/Bortezomib.html","C19H25BN4O4","Free Base","Velcade, LDP-341, MLM341, NSC 681239,PS-341","CC(C)CC(NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)B(O)O",2.183,4,2,9]
["S1014","Bosutinib (SKI-606)","b3","L3800-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Autophagy,Bcr-Abl,ERK,S6 Kinase,Src,STAT","Angiogenesis","Bosutinib (SKI-606) is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM in cell-free assays, respectively. Bosutinib also effectively decreases the activity of PI3K/AKT/mTOR, MAPK/ERK and JAK/STAT3 signaling pathways by blocking the phosphorylation levels of p-ERK, p-S6, and p-STAT3. Bosutinib promotes autophagy.",530.45,"380843-75-4",{"v":100,"d":"100.00"},188.52,"<1","N/A","http://selleckchem.com/products/Bosutinib.html","C26H29Cl2N5O3","free base","SKI-606","COC1=C(Cl)C=C(Cl)C(=C1)NC2=C(C=NC3=CC(=C(OC)C=C23)OCCCN4CCN(C)CC4)C#N",4.883,4,1,9]
["S1017","Cediranib (AZD2171)","c3","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","Autophagy,c-Kit,PDGFR,VEGFR","Protein Tyrosine Kinase","Cediranib (AZD2171, NSC-732208) is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-α, CSF-1R and Flt3 in HUVEC cells. Cediranib (AZD2171) induces autophagic vacuole accumulation. Phase 3.",450.51,"288383-20-0",{"v":90,"d":"90.00"},199.77,"<1","N/A","http://selleckchem.com/products/Cediranib.html","C25H27FN4O3","free base","NSC-732208","COC1=C(OCCCN2CCCC2)C=C3N=CN=C(OC4=C(F)C5=C([NH]C(=C5)C)C=C4)C3=C1",4.761,5,1,8]
["S1018","Dovitinib (TKI-258)","d3","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","c-Kit,FGFR,FLT3,PDGFR,VEGFR","Angiogenesis","Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGF-1R and HER2 in cell-free assays. Phase 4.",392.43,"405169-16-6",{"v":30,"d":"30.00"},76.45,"<1","N/A","http://selleckchem.com/products/CHIR-258.html","C21H21FN6O","Citrate","CHIR-258","CN1CCN(CC1)C2=CC3=C(C=C2)N=C([NH]3)C4=C(N)C5=C(NC4=O)C=CC=C5F",1.781,2,3,2]
["S1020","PD184352 (CI-1040)","e3","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,MEK","MAPK","PD184352 (CI-1040) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM in cell-based assays, 100-fold more selective for MEK1/2 than MEK5. PD184352 (CI-1040) selectively induces apoptosis.",478.67,"212631-79-3",{"v":96,"d":"96.00"},200.56,"<1","N/A","http://selleckchem.com/products/CI-1040-(PD184352).html","C17H14ClF2IN2O2","free base","N/A","FC1=CC=C(C(=O)NOCC2CC2)C(=C1F)NC3=CC=C(I)C=C3Cl",4.907,2,2,6]
["S1021","Dasatinib (BMS-354825)","f3","L3800-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,Bcr-Abl,c-Kit,Src","Angiogenesis","Dasatinib (BMS-354825) is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively. Dasatinib induces autophagy and apoptosis with anti-tumor activity.",488.01,"302962-49-8",{"v":98,"d":"98.00"},200.82,"<1","N/A","http://selleckchem.com/products/Dasatinib.html","C22H26ClN7O2S","free base","BMS-354825","CC1=NC(=CC(=N1)N2CCN(CCO)CC2)NC3=NC=C(S3)C(=O)NC4=C(Cl)C=CC=C4C",3.439,4,3,7]
["S1022","Ridaforolimus (Deforolimus, MK-8669)","g3","L3800-01","in 10mM DMSO","DMF","N/A","Phase 3","FKBP,mTOR","PI3K/Akt/mTOR","Ridaforolimus (Deforolimus, MK-8669, AP23573) is a selective mTOR inhibitor with IC50 of 0.2 nM in HT-1080 cell line; while not classified as a prodrug, mTOR inhibition and FKBP12 binding is similar to rapamycin. Phase 3.",990.21,"572924-54-0",{"v":198,"d":"198.00"},199.96,"<1","N/A","http://selleckchem.com/products/Deforolimus.html","C53H84NO14P","free base","AP23573","COC1CC(CCC1O[P](C)(C)=O)CC(C)C2CC(=O)C(C)\\C=C(C)\\C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC",6.303,12,1,8]
["S1025","Gefitinib (ZD1839)","h3","L3800-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","EP9.3;BP2019;IP2010","Marketed","Apoptosis related,Autophagy,EGFR","Protein Tyrosine Kinase","Gefitinib (ZD-1839, Iressa) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively. Gefitinib promotes autophagy and apoptosis of lung cancer cells via blockade of the PI3K/AKT/mTOR pathway.",{"v":446.9,"d":"446.90"},"184475-35-2",{"v":89,"d":"89.00"},199.15,"<1","N/A","http://selleckchem.com/products/Gefitinib.html","C22H24ClFN4O3","free base","Iressa,ZD1839","COC1=C(OCCCN2CCOCC2)C=C3C(=NC=NC3=C1)NC4=CC=C(F)C(=C4)Cl",4.203,5,1,8]
["S1026","Imatinib (STI571) Mesylate","a4","L3800-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","EP9.2;BP2019;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,Bcr-Abl,c-Kit,PDGFR","Protein Tyrosine Kinase","Imatinib (STI571, CGP057148B, Gleevec) Mesylate is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib Mesylate (STI571) induces autophagy.",589.71,"220127-57-1",{"v":118,"d":"118.00"},{"v":200.1,"d":"200.10"},{"v":118,"d":"118.00"},{"v":200.1,"d":"200.10"},"http://selleckchem.com/products/Imatinib-Mesylate.html","C29H31N7O.CH4SO3","Mesylate","Gleevec, Glivec, CGP-57148B,STI571","CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC=C(C)C(=C3)NC4=NC=CC(=N4)C5=CC=CN=C5.C[S](O)(=O)=O",3.806,4,2,7]
["S1028","Lapatinib (GW-572016) Ditosylate","b4","L3800-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","EGFR,HER2","Protein Tyrosine Kinase","Lapatinib (GW-572016) Ditosylate is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively.",925.46,"388082-77-7",{"v":100,"d":"100.00"},108.05,"<1","N/A","http://selleckchem.com/products/Lapatinib-Ditosylate.html","C29H26ClFN4O4S.2C7H8O3S","Ditosylat","GW-572016","CC1=CC=C(C=C1)[S](O)(=O)=O.CC2=CC=C(C=C2)[S](O)(=O)=O.C[S](=O)(=O)CCNCC3=CC=C(O3)C4=CC=C5N=CN=C(NC6=CC=C(OCC7=CC=CC(=C7)F)C(=C6)Cl)C5=C4",9.339,6,2,13]
["S1029","Lenalidomide (CC-5013)","c4","L3800-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Caspase,E3 Ligase ,E3 ligase Ligand,TNF-alpha,VEGFR","Ubiquitin","Lenalidomide (CC-5013) is a TNF-α secretion inhibitor with IC50 of 13 nM in PBMCs. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide promotes cleaved caspase-3 expression and inhibit VEGF expression and induces apoptosis.",259.26,"191732-72-6",{"v":52,"d":"52.00"},200.57,"<1","N/A","https://www.selleckchem.com/products/lenalidomide-s1029.html","C13H13N3O3","free base","CC-5013","NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1",-0.515,3,2,1]
["S1030","Panobinostat (LBH589)","d4","L3800-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,HDAC,HIV Protease","Epigenetics","Panobinostat (LBH589, NVP-LBH589) is a novel broad-spectrum HDAC inhibitor with IC50 of 5 nM in a cell-free assay. Panobinostat (LBH589) induces autophagy and apoptosis. Panobinostat effectively disrupts HIV latency in vivo. Phase 3.",349.43,"404950-80-7",{"v":69,"d":"69.00"},197.46,"<1","N/A","http://selleckchem.com/products/LBH-589.html","C21H23N3O2","Free Base","NVP-LBH589","CC1=C(CCNCC2=CC=C(\\C=C\\C(=O)NO)C=C2)C3=C([NH]1)C=CC=C3",3.194,1,3,7]
["S1032","Motesanib Diphosphate (AMG-706)","e4","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","c-Kit,PDGFR,VEGFR","Protein Tyrosine Kinase","Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit (c-Kit), ~10-fold more selective for VEGFR than PDGFR and Ret. Phase 3.",569.44,"857876-30-3",{"v":100,"d":"100.00"},175.61,{"v":19,"d":"19.00"},33.37,"http://selleckchem.com/products/Motesanib-Diphosphate.html","C22H23N5O.2H3PO4","Diphosphate","N/A","CC1(C)CNC2=CC(=CC=C12)NC(=O)C3=C(NCC4=CC=NC=C4)N=CC=C3.O[P](O)(O)=O.O[P](O)(O)=O",1.783,3,3,5]
["S1033","Nilotinib (AMN-107)","f4","L3800-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","EP9.8;Martindale:The Extra Pharmacopoeia","Marketed","AMPK,Autophagy,Bcr-Abl","Angiogenesis","Nilotinib (AMN-107) is a selective Bcr-Abl inhibitor with IC50 less than 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.",529.52,"641571-10-0",{"v":27,"d":"27.00"},50.99,"<1","N/A","http://selleckchem.com/products/Nilotinib.html","C28H22F3N7O","free base","AMN-107","CC1=C[N](C=N1)C2=CC(=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C)C(=C3)NC4=NC=CC(=N4)C5=CN=CC=C5",5.084,5,2,7]
["S1035","Pazopanib HCl (GW786034 HCl)","g4","L3800-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Autophagy,c-Kit,CSF-1R,FGFR,PDGFR,VEGFR","Protein Tyrosine Kinase","Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively. Pazopanib induces autophagic Type II cell death.",473.98,"635702-64-6",{"v":17,"d":"17.00"},35.87,"<1","N/A","http://selleckchem.com/products/Pazopanib-Hydrochloride.html","C21H23N7O2S.HCl","Hydrochloride","GW786034 HCl","Cl.C[N]1N=C2C=C(C=CC2=C1C)N(C)C3=NC(=NC=C3)NC4=CC=C(C)C(=C4)[S](N)(=O)=O",4.123,5,2,5]
["S1036","Mirdametinib (PD0325901)","h4","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","MEK","MAPK","Mirdametinib (PD0325901) is a selective and non ATP-competitive MEK inhibitor with IC50 of 0.33 nM in cell-free assays, roughly 500-fold more potent than CI-1040 on phosphorylation of ERK1 and ERK2. Phase 2.",482.19,"391210-10-9",{"v":96,"d":"96.00"},199.09,"<1","N/A","http://selleckchem.com/products/PD-0325901.html","C16H14F3IN2O4","free base","N/A","OCC(O)CONC(=O)C1=C(NC2=CC=C(I)C=C2F)C(=C(F)C=C1)F",2.578,2,4,7]
["S1039","Rapamycin (AY-22989)","a5","L3800-01","in 10mM DMSO","DMF","N/A","Marketed","Antineoplastic and Immunosuppressive Antibiotics,Autophagy,mTOR","PI3K/Akt/mTOR","Rapamycin (AY-22989, Rapamune, Sirolimus, NSC-2260804,AY-22989) is a specific mTOR inhibitor with IC50 of ~0.1 nM HEK293 cells.",914.18,"53123-88-9",{"v":20,"d":"20.00"},21.88,"<1","N/A","http://selleckchem.com/products/Rapamycin.html","C51H79NO13","free base","Rapamune, Sirolimus, NSC-2260804,AY-22989","COC1CC(CCC1O)CC(C)C2CC(=O)C(C)\\C=C(/C)C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC",6.295,10,2,6]
["S1040","Sorafenib (BAY 43-9006) tosylate","b5","L3800-01","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,c-Kit,Ferroptosis,FGFR,FLT3,PDGFR,Raf,VEGFR","MAPK","Sorafenib tosylate (BAY 43-9006 tosylate,NSC-724772 tosylate)  is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib Tosylate inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib Tosylate induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.",637.03,"475207-59-1",{"v":127,"d":"127.00"},199.36,0.01,0.02,"http://selleckchem.com/products/Sorafenib-Tosylate.html","C21H16ClF3N4O3.C7H8O3S","Tosylate","BAY 43-9006 tosylate,NSC-724772 tosylate","CNC(=O)C1=CC(=CC=N1)OC2=CC=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2.CC4=CC=C(C=C4)[S](O)(=O)=O",5.824,4,3,7]
["S1042","Sunitinib (SU11248) malate","c5","L3800-01","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,c-Kit,IRE1,Mitophagy,PDGFR,VEGFR","Protein Tyrosine Kinase","Sunitinib (SU11248) malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM in cell-free assays, and also inhibits c-Kit. Sunitinib Malate effectively inhibits autophosphorylation of Ire1α. Sunitinib Malate increases both death receptor and mitochondrial-dependent apoptosis.",532.56,"341031-54-7",{"v":15,"d":"15.00"},28.17,"<1","N/A","http://selleckchem.com/products/Sunitinib-Malate-(Sutent).html","C22H27FN4O2.C4H6O5","Malate","N/A","CCN(CC)CCNC(=O)C1=C(C)[NH]C(=C1C)/C=C/2C(=O)NC3=CC=C(F)C=C23.OC(CC(O)=O)C(O)=O",-1.049,4,4,10]
["S1044","Temsirolimus (CCI-779)","d5","L3800-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,mTOR","PI3K/Akt/mTOR","Temsirolimus (CCI-779, NSC 683864) is a specific mTOR inhibitor with IC50 of 1.76 μM in a cell-free assay. Temsirolimus induces autophagy and apoptosis.",1030.29,"162635-04-3",{"v":67,"d":"67.00"},65.03,"<1","N/A","http://selleckchem.com/products/Temsirolimus.html","C56H87NO16","free base","NSC 683864,CCI-779","COC1CC(CCC1OC(=O)C(C)(CO)CO)CC(C)C2CC(=O)C(C)\\C=C(C)\\C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC",6.039,12,3,11]
["S1047","Vorinostat (SAHA)","e5","L3800-01","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,HDAC,HPV","Epigenetics","Vorinostat (SAHA,MK0683, Suberoylanilide hydroxamic acid, Zolinza) is an HDAC inhibitor with IC50 of ~10 nM in a cell-free assay. Vorinostat abrogates productive HPV-18 DNA amplification.",{"v":264.3,"d":"264.30"},"149647-78-9",{"v":52,"d":"52.00"},196.75,"<1","N/A","http://selleckchem.com/products/Vorinostat-saha.html","C14H20N2O3","free base","SAHA,MK0683, Suberoylanilide hydroxamic acid, Zolinza","ONC(=O)CCCCCCC(=O)NC1=CC=CC=C1",2.005,2,2,8]
["S1048","Tozasertib","f5","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","Aurora Kinase,Autophagy,Bcr-Abl,FLT3","Cell Cycle","Tozasertib (VX-680, MK-0457) is a pan-Aurora inhibitor, mostly against Aurora A with Kiapp of 0.6 nM in a cell-free assay, less potent towards Aurora B/Aurora C and 100-fold more selective for Aurora A than 55 other kinases. The only exceptions are Fms-related tyrosine kinase-3 (FLT-3) and BCR-ABL tyrosine kinase, which are inhibited by the Tozasertib with both Ki of 30 nM. Tozasertib induces apoptosis and autophagy. Phase 2.",464.59,"639089-54-6",{"v":93,"d":"93.00"},200.18,"<1","N/A","http://selleckchem.com/products/VX-680(MK-0457).html","C23H28N8OS","free base","VX-680, MK-0457","CN1CCN(CC1)C2=NC(=NC(=C2)NC3=N[NH]C(=C3)C)SC4=CC=C(NC(=O)C5CC5)C=C4",4.445,4,3,7]
["S1052","Elesclomol (STA-4783)","g5","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","Apoptosis related,HSP (HSP90)","Cytoskeletal Signaling","Elesclomol (STA-4783) is a novel potent oxidative stress inducer that elicits pro-apoptosis events among tumor cells. Phase 3.Elesclomol specifically binds ferredoxin 1 (FDX1) α2/α3 helices and β5 strand and inhibits FDX1-mediated Fe-S cluster biosynthesis.",{"v":400.5,"d":"400.50"},"488832-69-5",{"v":80,"d":"80.00"},199.75,"<1","N/A","http://selleckchem.com/products/Elesclomol.html","C19H20N4O2S2","free base","N/A","CN(NC(=O)CC(=O)NN(C)C(=S)C1=CC=CC=C1)C(=S)C2=CC=CC=C2",2.885,2,2,8]
["S1053","Entinostat (MS-275)","h5","L3800-01","in 10mM DMSO","DMF","N/A","Phase 3","Apoptosis related,Autophagy,HDAC","Epigenetics","Entinostat (MS-275, SNDX-275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM in cell-free assays, compared with HDACs 4, 6, 8, and 10. Entinostat induces autophagy and apoptosis. Phase 3.",376.41,"209783-80-2",{"v":75,"d":"75.00"},199.25,"<1","N/A","http://selleckchem.com/products/MS-275.html","C21H20N4O3","free base","SNDX-275","NC1=CC=CC=C1NC(=O)C2=CC=C(CNC(=O)OCC3=CN=CC=C3)C=C2",2.071,4,3,7]
["S1055","Enzastaurin (LY317615)","a6","L3800-01","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","Phase 3","PKC","TGF-beta/Smad","Enzastaurin (LY317615) is a potent PKCβ selective inhibitor with IC50 of 6 nM in cell-free assays, 6- to 20-fold selectivity against PKCα, PKCγ and PKCε. Phase 3.",515.61,"170364-57-5",{"v":30,"d":"30.00"},58.18,"<1","N/A","http://selleckchem.com/products/Enzastaurin.html","C32H29N5O2","free base","N/A","C[N]1C=C(C2=CC=CC=C12)C3=C(C(=O)NC3=O)C4=C[N](C5CCN(CC5)CC6=NC=CC=C6)C7=CC=CC=C47",{"v":4.32,"d":"4.320"},3,1,5]
["S1057","Obatoclax Mesylate (GX15-070)","b6","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","Autophagy,Bcl-2","Apoptosis","Obatoclax Mesylate (GX15-070) is an antagonist of Bcl-2 with Ki of 0.22 μM in a cell-free assay, can assist in overcoming MCL-1 mediated resistance to apoptosis.",413.49,"803712-79-0",{"v":83,"d":"83.00"},200.73,"<1","N/A","http://selleckchem.com/products/Obatoclax-Mesylate.html","C20H19N3O.CH4O3S","Mesylate","N/A","COC\\1=CC(=NC1=C\\C2=C(C)C=C(C)[NH]2)C3=CC4=CC=CC=C4[NH]3.C[S](O)(=O)=O",3.757,2,2,3]
["S1060","Olaparib (AZD2281)","c6","L3800-01","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,Mitophagy,PARP","DNA Damage/DNA Repair","Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1. Olaparib induces significant autophagy that is associated with mitophagy in cells with BRCA mutations.",434.46,"763113-22-0",{"v":86,"d":"86.00"},197.95,"N/A","N/A","http://selleckchem.com/products/AZD2281(Olaparib).html","C24H23FN4O3","free base","Ku-0059436","FC1=C(C=C(CC2=NNC(=O)C3=C2C=CC=C3)C=C1)C(=O)N4CCN(CC4)C(=O)C5CC5",2.127,4,1,4]
["S1064","Masitinib (AB1010)","d6","L3800-01","in 10mM DMSO","DMF,EMA","N/A","Preregistration","c-Kit,PDGFR","Protein Tyrosine Kinase","Masitinib is a novel inhibitor for Kit (c-Kit) and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms. Phase 3.",498.64,"790299-79-5",{"v":100,"d":"100.00"},200.55,"<1","N/A","http://selleckchem.com/products/Masitinib-(AB1010).html","C28H30N6OS","free base","N/A","CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC(=C(C)C=C3)NC4=NC(=CS4)C5=CC=CN=C5",4.475,3,2,7]
["S1065","Pictilisib (GDC-0941)","e6","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,Autophagy,PI3K","PI3K/Akt/mTOR","Pictilisib (GDC-0941, RG7321) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM in cell-free assays, with modest selectivity against p110β (11-fold) and p110γ (25-fold). Pictilisib (GDC-0941) induces autophagy and apoptosis. Phase 2.",513.64,"957054-30-7",{"v":44,"d":"44.00"},85.66,"<1","N/A","http://selleckchem.com/products/GDC-0941.html","C23H27N7O3S2","free base","RG7321","C[S](=O)(=O)N1CCN(CC1)CC2=CC3=NC(=NC(=C3S2)N4CCOCC4)C5=CC=CC6=C5C=N[NH]6",2.153,6,1,5]
["S1068","Crizotinib (PF-02341066)","f6","L3800-01","in 10mM DMSO","FDA,EMA,NDC,PMDA","N/A","Marketed","ALK,Autophagy,c-Met,ROS1","Protein Tyrosine Kinase","Crizotinib (PF-02341066) is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM in cell-based assays, respectively. It is also a potent ROS1 inhibitor with Ki value less than 0.025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines.",450.34,"877399-52-5",{"v":9,"d":"9.00"},19.98,"<1","N/A","http://selleckchem.com/products/PF-2341066.html","C21H22Cl2FN5O","free base","PF-02341066","CC(OC1=C(N)N=CC(=C1)C2=C[N](N=C2)C3CCNCC3)C4=C(Cl)C=CC(=C4Cl)F",3.693,3,2,5]
["S1069","Luminespib (NVP-AUY922)","g6","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,Autophagy,HSP (HSP90),IGF-1R","Cytoskeletal Signaling","Luminespib (AUY-922, NVP-AUY922, VER-52296) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM in cell-free assays, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Luminespib (AUY-922, NVP-AUY922) effectively downregulates and destabilizes the IGF-1Rβ protein and results in growth inhibition, autophagy and apoptosis. Phase 2.",465.54,"747412-49-3",{"v":93,"d":"93.00"},199.77,"<1","N/A","http://selleckchem.com/products/NVP-AUY922.html","C26H31N3O5","free base","AUY-922, VER-52296","CCNC(=O)C1=NOC(=C1C2=CC=C(CN3CCOCC3)C=C2)C4=CC(=C(O)C=C4O)C(C)C",4.069,4,3,7]
["S1072","ZSTK474","h6","L3800-01","in 10mM DMSO","N/A","N/A","Phase 1","PI3K","PI3K/Akt/mTOR","ZSTK474 inhibits class I PI3K isoforms with IC50 of 37 nM in a cell-free assay, mostly PI3Kδ. Phase1/2.",417.41,"475110-96-4",{"v":21,"d":"21.00"},50.31,"<1","N/A","http://selleckchem.com/products/ZSTK474.html","C19H21F2N7O2","free base","N/A","FC(F)C1=NC2=C(C=CC=C2)[N]1C3=NC(=NC(=N3)N4CCOCC4)N5CCOCC5",3.366,6,0,4]
["S1078","MK-2206 2HCl","a7","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","Akt,Apoptosis related,Autophagy","PI3K/Akt/mTOR","MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM in cell-free assays, respectively; no inhibitory activities against 250 other protein kinases observed. MK-2206 2HCl induces autophagy and apoptosis in cancer cells. Phase 2.",480.39,"1032350-13-2",{"v":14,"d":"14.00"},29.14,"<1","N/A","http://selleckchem.com/products/MK-2206.html","C25H21N5O.2HCl","Dihydrochloride","N/A","Cl.Cl.NC1(CCC1)C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C(=O)NN=C45)C6=CC=CC=C6",4.183,3,2,3]
["S1082","Vismodegib (GDC-0449)","b7","L3800-01","in 10mM DMSO","FDA,EMA,NDC","N/A","Marketed","Hedgehog/Smoothened","Stem Cells & Wnt","Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay.",{"v":421.3,"d":"421.30"},"879085-55-9",{"v":84,"d":"84.00"},199.38,"<1","N/A","http://selleckchem.com/products/GDC-0449.html","C19H14Cl2N2O3S","free base","GDC-0449","C[S](=O)(=O)C1=CC=C(C(=C1)Cl)C(=O)NC2=CC(=C(Cl)C=C2)C3=NC=CC=C3",4.265,4,1,4]
["S1084","Brivanib (BMS-540215)","c7","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","FGFR,VEGFR","Protein Tyrosine Kinase","Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.",370.38,"649735-46-6",{"v":74,"d":"74.00"},199.79,"<1","N/A","http://selleckchem.com/products/Brivanib.html","C19H19FN4O3","free base","N/A","CC(O)COC1=C[N]2N=CN=C(OC3=C(F)C4=C([NH]C(=C4)C)C=C3)C2=C1C",3.481,4,2,5]
["S1085","Belinostat (PXD101)","d7","L3800-01","in 10mM DMSO","FDA,DMF,NDC","N/A","Marketed","Autophagy,HDAC","Epigenetics","Belinostat (PXD101, NSC726630, PX-105684) is a novel HDAC inhibitor with IC50 of 27 nM in a cell-free assay, with activity demonstrated in cisplatin-resistant tumors. Belinostat (PXD101) induces autophagy.",318.35,"866323-14-0",{"v":64,"d":"64.00"},201.04,"<1","N/A","http://selleckchem.com/products/Belinostat.html","C15H14N2O4S","free base","PXD101,NSC726630, PX-105684","ONC(=O)/C=C/C1=CC(=CC=C1)[S](=O)(=O)NC2=CC=CC=C2",{"v":1.8,"d":"1.800"},3,2,5]
["S1087","Iniparib (BSI-201)","e7","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","PARP","DNA Damage/DNA Repair","Iniparib (BSI-201, NSC-746045, IND-71677) is a PARP1 inhibitor with demonstrated effectiveness in triple-negative breast cancer (TNBC). Phase 3.",292.03,"160003-66-7",{"v":58,"d":"58.00"},198.61,"<1","N/A","http://selleckchem.com/products/BSI-201.html","C7H5IN2O3","free base","NSC-746045, IND-71677","NC(=O)C1=CC(=C(I)C=C1)[N+]([O-])=O",1.304,1,1,2]
["S1089","Refametinib (RDEA119)","f7","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","MEK","MAPK","Refametinib (RDEA119, Bay 86-9766) is a potent, ATP non-competitive and highly selective inhibitor of MEK1 and MEK2 with IC50 of 19 nM and 47 nM, respectively.",572.34,"923032-37-5",{"v":100,"d":"100.00"},174.72,"<1","N/A","http://selleckchem.com/products/refametinib-rdea119-bay86-9766.html","C19H20F3IN2O5S","free base","Bay 86-9766","COC1=C(N[S](=O)(=O)C2(CC2)CC(O)CO)C(=C(F)C(=C1)F)NC3=CC=C(I)C=C3F",2.827,3,4,9]
["S1090","Abexinostat (PCI-24781)","g7","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","HDAC","Cytoskeletal Signaling","Abexinostat (PCI-24781, CRA-024781) is a novel pan-HDAC inhibitor mostly targeting HDAC1 with Ki of 7 nM, modest potent to HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2.",397.42,"783355-60-2",{"v":80,"d":"80.00"},{"v":201.3,"d":"201.30"},"<1","N/A","http://selleckchem.com/products/PCI-24781.html","C21H23N3O5","free base","CRA-024781","CN(C)CC1=C(OC2=CC=CC=C12)C(=O)NCCOC3=CC=C(C=C3)C(=O)NO",2.353,4,2,8]
["S1091","Linsitinib (OSI-906)","h7","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","IGF-1R","Protein Tyrosine Kinase","Linsitinib (OSI-906) is a selective inhibitor of IGF-1R with IC50 of 35 nM in cell-free assays; modestly potent to InsR with IC50 of 75 nM, and no activity towards Abl, ALK, BTK, EGFR, FGFR1/2, PKA etc. Phase 3.",421.49,"867160-71-2",{"v":84,"d":"84.00"},199.29,"<1","N/A","http://selleckchem.com/products/OSI-906.html","C26H23N5O","free base","N/A","CC1(O)CC(C1)C2=NC(=C3[N]2C=CN=C3N)C4=CC=C5C=CC(=NC5=C4)C6=CC=CC=C6",3.757,3,1,3]
["S1094","PF-04217903","a8","L3800-01","in 10mM DMSO","N/A","N/A","Phase 1","c-Met","Protein Tyrosine Kinase","PF-04217903 is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM in A549 cell line, susceptible to oncogenic mutations (no activity to Y1230C mutant). Phase 1.",372.38,"956905-27-4",{"v":5,"d":"5.00"},13.43,"<1","N/A","http://selleckchem.com/products/PF-04217903.html","C19H16N8O","free base","N/A","OCC[N]1C=C(C=N1)C2=NC3=C(N=C2)N=N[N]3CC4=CC5=CC=CN=C5C=C4",1.561,6,1,5]
["S1095","Dacinostat (LAQ824)","b8","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","HDAC,p21","Epigenetics","Dacinostat (LAQ824, NVP-LAQ824) is a novel HDAC inhibitor with IC50 of 32 nM and is known to activate the p21 promoter.",379.46,"404951-53-7",{"v":76,"d":"76.00"},200.29,"<1","N/A","http://selleckchem.com/products/LAQ824(NVP-LAQ824).html","C22H25N3O3","free base","NVP-LAQ824","OCCN(CCC1=C[NH]C2=C1C=CC=C2)CC3=CC=C(\\C=C\\C(=O)NO)C=C3",3.045,1,3,9]
["S1096","Quisinostat (JNJ-26481585) 2HCl","c8","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","HDAC","Epigenetics","Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.",467.39,"875320-31-3",{"v":79,"d":"79.00"},169.02,"<1","N/A","http://selleckchem.com/products/JNJ-26481585.html","C21H28Cl2N6O2","Dihydrochloride","N/A","Cl.Cl.C[N]1C=C(CNCC2CCN(CC2)C3=NC=C(C=N3)C(=O)NO)C4=CC=CC=C14",2.749,3,2,6]
["S1098","Rucaparib (AG-014699) phosphate","d8","L3800-01","in 10mM DMSO","FDA,EMA,NDC","N/A","Marketed","PARP","DNA Damage/DNA Repair","Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains. Phase 3.",421.36,"459868-92-9",{"v":84,"d":"84.00"},199.35,"<1","N/A","http://selleckchem.com/products/AG-014699.html","C19H18FN3O.H3PO4","Phosphate","PF-01367338","CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=CC(=CC(=C34)[NH]2)F.O[P](O)(O)=O",{"v":2.49,"d":"2.490"},1,3,3]
["S1100","MLN8054","e8","L3800-01","in 10mM DMSO","N/A","N/A","Phase 1","Aurora Kinase","Cell Cycle","MLN8054 is a potent and selective inhibitor of Aurora A with IC50 of 4 nM in Sf9 insect cell. It is more than 40-fold selective for Aurora A than Aurora B. Phase 1.",476.86,"869363-13-3",{"v":95,"d":"95.00"},199.22,"<1","N/A","http://selleckchem.com/products/MLN8054.html","C25H15ClF2N4O2","free base","N/A","OC(=O)C1=CC=C(NC2=NC3=C(CN=C(C4=CC(=CC=C34)Cl)C5=C(F)C=CC=C5F)C=N2)C=C1",6.192,4,1,4]
["S1101","Vatalanib (PTK787) 2HCl","f8","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","VEGFR","Protein Tyrosine Kinase","Vatalanib 2HCl (PTK787, ZK 222584, cpg-79787) is an inhibitor of VEGFR2/KDR with IC50 of 37 nM in a cell-free assay, less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4. Phase 3.",419.73,"212141-51-0",{"v":85,"d":"85.00"},202.51,{"v":10,"d":"10.00"},23.82,"http://selleckchem.com/products/Vatalanib,Dihydrochloride-Salt.html","C20H15ClN4.2HCl","Dihydrochloride","ZK 222584 (cpg-79787) 2HCl","Cl.Cl.ClC1=CC=C(NC2=NN=C(CC3=CC=NC=C3)C4=CC=CC=C24)C=C1",5.469,3,1,4]
["S1105","LY294002","g8","L3800-01","in 10mM DMSO","N/A","N/A","Phase 1","Apoptosis related,Autophagy,Casein Kinase,DNA-PK,PI3K","PI3K/Akt/mTOR","LY294002 (SF 1101, NSC 697286) is the first synthetic molecule known to inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation. It not only binds to class I PI3Ks and other PI3K-related kinases, but also to novel targets seemingly unrelated to the PI3K family. LY294002 also inhibits CK2 with IC50 of 98 nM. LY294002 is a non-specific DNA-PKcs inhibitor and activates autophagy and apoptosis.",307.34,"154447-36-6",{"v":36,"d":"36.00"},117.13,"<1","N/A","http://selleckchem.com/products/LY294002.html","C19H17NO3","free base","SF 1101, NSC 697286","O=C1C=C(OC2=C(C=CC=C12)C3=CC=CC=C3)N4CCOCC4",3.342,3,0,2]
["S1106","OSU-03012 (AR-12)","h8","L3800-01","in 10mM DMSO","N/A","N/A","Phase 1","PDPK1","PI3K/Akt/mTOR","OSU-03012 (AR-12) is a potent inhibitor of recombinant PDK-1(phosphoinositide-dependent kinase 1) with IC50 of 5 μM in a cell-free assay and 2-fold increase in potency over OSU-02067.",460.45,"742112-33-0",{"v":11,"d":"11.00"},23.89,"<1","N/A","http://selleckchem.com/products/OSU-03012.html","C26H19F3N4O","free base","N/A","NCC(=O)NC1=CC=C(C=C1)[N]2N=C(C=C2C3=CC4=C(C=C3)C5=C(C=CC=C5)C=C4)C(F)(F)F",5.212,2,2,5]
["S1107","Danusertib (PHA-739358)","a9","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,Aurora Kinase,Autophagy,Bcr-Abl,c-RET,FGFR,Trk receptor","Cell Cycle","Danusertib (PHA-739358) is an Aurora kinase inhibitor for Aurora A/B/C with IC50 of 13 nM/79 nM/61 nM in cell-free assays, modestly potent to Abl, TrkA, c-RET and FGFR1, and less potent to Lck, VEGFR2/3, c-Kit, CDK2, etc. Danusertib induces apoptosis, cell cycle arrest, and autophagy. Phase 2.",474.55,"827318-97-8",{"v":95,"d":"95.00"},200.19,"<1","N/A","http://selleckchem.com/products/PHA-739358(Danusertib).html","C26H30N6O3","free base","N/A","COC(C(=O)N1CC2=C(C1)C(=N[NH]2)NC(=O)C3=CC=C(C=C3)N4CCN(C)CC4)C5=CC=CC=C5",2.337,4,2,6]
["S1109","BI 2536","b9","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,Autophagy,Epigenetic Reader Domain,Myc,PLK","Cell Cycle","BI-2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM in a cell-free assay. BI-2536 inhibits Bromodomain 4 (BRD4) with Kd of 37 nM and potently suppresses c-Myc expression. BI-2536 induces apoptosis and attenuates autophagy. Phase 2.",521.66,"755038-02-9",{"v":21,"d":"21.00"},40.26,"<1","N/A","http://selleckchem.com/products/BI-2536.html","C28H39N7O3","free base","N/A","CCC1N(C2CCCC2)C3=NC(=NC=C3N(C)C1=O)NC4=CC=C(C=C4OC)C(=O)NC5CCN(C)CC5",3.548,5,2,7]
["S1110","Varespladib (LY315920)","c9","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","Phospholipase (e.g. PLA)","Metabolism","Varespladib (LY315920) is a potent and selective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor with IC50 of 7 nM. Phase 3.",380.39,"172732-68-2",{"v":76,"d":"76.00"},199.79,"<1","N/A","http://selleckchem.com/products/LY315920(Varespladib).html","C21H20N2O5","free base","N/A","CCC1=C(C(=O)C(N)=O)C2=C(C=CC=C2OCC(O)=O)[N]1CC3=CC=CC=C3",3.078,4,1,8]
["S1111","Foretinib (GSK1363089)","d9","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","c-Kit,c-Met,FLT3,PDGFR,VEGFR","Protein Tyrosine Kinase","Foretinib (GSK1363089, EXEL-2880, XL-880, GSK089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met (c-Met) and KDR with IC50 of 0.4 nM and 0.9 nM in cell-free assays. Less potent against Ron, Flt-1/3/4, Kit (c-Kit), PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR. Phase 2.",632.65,"849217-64-7",{"v":100,"d":"100.00"},158.07,"<1","N/A","http://selleckchem.com/products/XL880(GSK1363089,EXEL-2880).html","C34H34F2N4O6","free base","EXEL-2880, XL-880, GSK089","COC1=CC2=C(C=C1OCCCN3CCOCC3)N=CC=C2OC4=C(F)C=C(NC(=O)C5(CC5)C(=O)NC6=CC=C(F)C=C6)C=C4",4.437,7,2,12]
["S1113","GSK690693","e9","L3800-01","in 10mM DMSO","N/A","N/A","Phase 1","Akt,AMPK,Autophagy,DAPK,PKA,PKC,STING,ULK","PI3K/Akt/mTOR","GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM in cell-free assays, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. GSK690693 also potently inhibits AMPK and DAPK3 from the CAMK family with IC50 of 50 nM and 81 nM, respectively. GSK690693 affects Unc-51-like autophagy activating kinase 1 (ULK1) activity, robustly inhibits STING-dependent IRF3 activation. Phase 1.",425.48,"937174-76-0",{"v":39,"d":"39.00"},91.66,"<1","N/A","http://selleckchem.com/products/GSK690693.html","C21H27N7O3","free base","N/A","CC[N]1C(=NC2=C1C(=CN=C2C#CC(C)(C)O)OCC3CCCNC3)C4=NON=C4N",1.839,6,2,7]
["S1114","JNJ-38877605","f9","L3800-01","in 10mM DMSO","N/A","N/A","Phase 1","c-Met","Protein Tyrosine Kinase","JNJ-38877605 is an ATP-competitive inhibitor of c-Met with IC50 of 4 nM, 600-fold selective for c-Met than 200 other tyrosine and serine-threonine kinases. Phase 1.",377.35,"943540-75-8",{"v":37,"d":"37.00"},98.05,"<1","N/A","http://selleckchem.com/products/JNJ-38877605.html","C19H13F2N7","free base","N/A","C[N]1C=C(C=N1)C2=N[N]3C(=NN=C3C(F)(F)C4=CC5=C(C=C4)N=CC=C5)C=C2",3.052,5,0,3]
["S1117","Triciribine (NSC 154020)","g9","L3800-01","in 10mM DMSO","N/A","N/A","Phase 1/2","Akt,DNA/RNA Synthesis,HIV","PI3K/Akt/mTOR","Triciribine (NSC 154020, VD-0002, vqd-002, API-2, TCN) is a DNA synthesis inhibitor, also inhibits Akt in PC3 cell line and HIV-1 in CEM-SS, H9, H9IIIB, U1 cells with IC50 of 130 nM and 20 nM, respectively; does not inhibit PI3K/PDK1; 5000-fold less active in cells lacking adenosine kinase. Phase 1/2.",{"v":320.3,"d":"320.30"},"35943-35-2",{"v":64,"d":"64.00"},199.81,"<1","N/A","http://selleckchem.com/products/Triciribine.html","C13H16N6O4","free base","VD-0002, vqd-002, API-2, TCN","CN1N=C(N)C2=C[N](C3OC(CO)C(O)C3O)C4=C2C1=NC=N4",-1.119,4,4,2]
["S1119","Cabozantinib (BMS-907351)","h9","L3800-01","in 10mM DMSO","FDA,DMF,EMA,NDC","N/A","Marketed","Apoptosis related,Axl,c-Met,VEGFR","Protein Tyrosine Kinase","Cabozantinib (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively. Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway.",501.51,"849217-68-1",{"v":100,"d":"100.00"},{"v":199.4,"d":"199.40"},"<1","N/A","http://selleckchem.com/products/XL184.html","C28H24FN3O5","Free Base","XL184,BMS-907351","COC1=CC2=C(C=C1OC)C(=CC=N2)OC3=CC=C(NC(=O)C4(CC4)C(=O)NC5=CC=C(F)C=C5)C=C3",4.342,6,2,8]
["S1120","Everolimus (RAD001)","a10","L3800-01","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","EP9.7;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,FKBP,mTOR","PI3K/Akt/mTOR","Everolimus (RAD001, SDZ-RAD, Afinitor) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM in a cell-free assay. Everolimus induces cell apoptosis and autophagy and inhibits tumor cells proliferation.",958.22,"159351-69-6",{"v":100,"d":"100.00"},104.36,"<1","N/A","http://selleckchem.com/products/Everolimus(RAD001).html","C53H83NO14","free base","RAD001,SDZ-RAD, Afinitor","COC1CC(CCC1OCCO)CC(C)C2CC(=O)C(C)\\C=C(C)\\C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC",6.164,11,2,9]
["S1122","Mocetinostat (MGCD0103)","b10","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,Autophagy,HDAC","Epigenetics","Mocetinostat (MGCD0103, MG0103) is a potent HDAC inhibitor with most potency for HDAC1 with IC50 of 0.15 μM in a cell-free assay, 2- to 10- fold selectivity against HDAC2, 3, and 11, and no activity to HDAC4, 5, 6, 7, and 8. Mocetinostat (MGCD0103) induces apoptosis and autophagy. Phase 2.",396.44,"726169-73-9",{"v":13,"d":"13.00"},32.79,"<1","N/A","http://selleckchem.com/products/MGCD0103(Mocetinostat).html","C23H20N6O","free base","MG0103","NC1=CC=CC=C1NC(=O)C2=CC=C(CNC3=NC=CC(=N3)C4=CC=CN=C4)C=C2",2.798,4,3,6]
["S1124","BMS-754807","c10","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","c-Met,IGF-1R,RON,Trk receptor","Protein Tyrosine Kinase","BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM in cell-free assays, less potent to Met (c-Met), Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc. Phase 2.",461.49,"1001350-96-4",{"v":92,"d":"92.00"},199.35,"<1","N/A","http://selleckchem.com/products/BMS-754807.html","C23H24FN9O","free base","N/A","CC1(CCCN1C2=N[N]3C=CC=C3C(=N2)NC4=N[NH]C(=C4)C5CC5)C(=O)NC6=CC=C(F)N=C6",4.069,5,3,6]
["S1130","Sepantronium Bromide","d10","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","Autophagy,IAP,Survivin","Apoptosis","Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM in HeLa-SURP-luc and CHO-SV40-luc cells; does not significantly inhibit SV40 promoter activity, but is observed to slightly inhibit the interaction of Survivin with XIAP. YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells. Phase 2.",443.29,"781661-94-7",{"v":55,"d":"55.00"},124.07,{"v":89,"d":"89.00"},200.77,"http://selleckchem.com/products/YM155.html","C20H19BrN4O3","Bromide","YM155","[Br-].COCC[N]1C(=[N+](CC2=CN=CC=N2)C3=C1C(=O)C4=C(C=CC=C4)C3=O)C",-0.733,5,0,5]
["S1133","Alisertib (MLN8237)","e10","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","Apoptosis related,Aurora Kinase,Autophagy","Cell Cycle","Alisertib (MLN8237) is a selective Aurora A inhibitor with IC50 of 1.2 nM in a cell-free assay. It has >200-fold higher selectivity for Aurora A than Aurora B. Alisertib induces cell cycle arrest, apoptosis and autophagy. Phase 3.",518.92,"1028486-01-2",{"v":27,"d":"27.00"},52.03,"<1","N/A","http://selleckchem.com/products/MLN8237.html","C27H20ClFN4O4","free base","N/A","COC1=C(C(=CC=C1)F)C2=NCC3=C(N=C(NC4=CC(=C(C=C4)C(O)=O)OC)N=C3)C5=C2C=C(Cl)C=C5",5.954,6,1,6]
["S1134","AT9283","f10","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","Aurora Kinase,Bcr-Abl,JAK","JAK/STAT","AT9283 is a potent JAK2/3 inhibitor with IC50 of 1.2 nM/1.1 nM in cell-free assays; also potent to Aurora A/B, Abl1(T315I).",381.43,"896466-04-9",{"v":76,"d":"76.00"},199.25,"<1","N/A","http://selleckchem.com/products/AT9283.html","C19H23N7O2","free base","N/A","O=C(NC1CC1)NC2=C[NH]N=C2C3=NC4=CC(=CC=C4[NH]3)CN5CCOCC5",{"v":1.51,"d":"1.510"},4,4,5]
["S1137","Malotilate","g10","L3800-01","in 10mM DMSO","CFDA,DMF,PMDA","Martindale:The Extra Pharmacopoeia","N/A","Lipoxygenase","Metabolism","Malotilate (NKK105) is a drug used for the treatment of liver cirrhosis. Malotilate is a liver protein metabolism improved compound, which selectively inhibit the 5-lipoxygenase.",288.38,"59937-28-9",{"v":58,"d":"58.00"},201.12,"<1","N/A","http://selleckchem.com/products/Malotilate.html","C12H16O4S2","free base","NKK105","CC(C)OC(=O)C(C(=O)OC(C)C)=C1SC=CS1",2.363,4,0,6]
["S1138","Brivanib Alaninate (BMS-582664)","h10","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","FGFR,VEGFR","Protein Tyrosine Kinase","Brivanib alaninate (BMS-582664) is the prodrug of BMS-540215, an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM.",441.46,"649735-63-7",{"v":88,"d":"88.00"},199.34,"<1","N/A","http://selleckchem.com/products/Brivanib-alaninate.html","C22H24FN5O4","Alaninate","N/A","CC(N)C(=O)OC(C)COC1=C[N]2N=CN=C(OC3=C(F)C4=C([NH]C(=C4)C)C=C3)C2=C1C",3.383,6,2,8]
["S1141","Tanespimycin (17-AAG)","a11","L3800-01","in 10mM DMSO","N/A","N/A","Phase 3","Apoptosis related,Autophagy,HSP (HSP90),Mitophagy","Cytoskeletal Signaling","Tanespimycin (17-AAG, CP127374, NSC-330507, KOS 953) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. Tanespimycin (17-AAG) induces apoptosis, necrosis, autophagy and mitophagy. Phase 3.",585.69,"75747-14-7",{"v":100,"d":"100.00"},170.74,"<1","N/A","http://selleckchem.com/products/17-AAG(Geldanamycin).html","C31H43N3O8","free base","CP127374, NSC-330507, KOS 953","COC1CC(C)CC2=C(NCC=C)C(=O)C=C(NC(=O)C(=C\\C=C/C(OC)C(OC(N)=O)/C(=C/C(C)C1O)C)\\C)C2=O",2.524,7,4,7]
["S1142","Alvespimycin (17-DMAG) HCl","b11","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","HSP (HSP90)","Cytoskeletal Signaling","Alvespimycin (17-DMAG, NSC 707545, BMS 826476, KOS 1022) HCl is a potent HSP90 inhibitor with IC50 of 62 nM in a cell-free assay.",653.21,"467214-21-7",{"v":131,"d":"131.00"},200.55,"<1","N/A","http://selleckchem.com/products/17-DMAG,Hydrochloride-Salt.html","C32H48N4O8.HCl","Hydrochloride","NSC 707545,BMS 826476 HCl,KOS 1022","Cl.COC1CC(C)CC2=C(NCCN(C)C)C(=O)C=C(NC(=O)C(=C\\C=C/C(OC)C(OC(N)=O)/C(=C/C(C)C1O)C)\\C)C2=O",2.428,7,4,8]
["S1144","Ivacaftor (VX-770)","c11","L3800-01","in 10mM DMSO","FDA,DMF,EMA,NDC","N/A","Marketed","CFTR","Transmembrane Transporters","Ivacaftor (VX-770) is a selective potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM in fisher rat thyroid cells, respectively.",392.49,"873054-44-5",{"v":78,"d":"78.00"},198.73,"<1","N/A","http://selleckchem.com/products/VX-770.html","C24H28N2O3","free base","VX-770","CC(C)(C)C1=CC(=C(NC(=O)C2=CNC3=C(C=CC=C3)C2=O)C=C1O)C(C)(C)C",4.516,2,3,4]
["S1145","SNS-032 (BMS-387032)","d11","L3800-01","in 10mM DMSO","N/A","N/A","Phase 1","Apoptosis related,CDK","Cell Cycle","SNS-032 (BMS-387032) has firstly been described as a selective inhibitor of CDK2 with IC50 of 48 nM in cell-free assays and is 10- and 20-fold selective over CDK1/CDK4. It is also found to be sensitive to CDK7/9 with IC50 of 62 nM/4 nM, with little effect on CDK6. SNS-032 (BMS-387032) induces apoptosis.",380.53,"345627-80-7",{"v":76,"d":"76.00"},199.72,"<1","N/A","http://selleckchem.com/products/SNS-032.html","C17H24N4O2S2","free base","N/A","CC(C)(C)C1=CN=C(CSC2=CN=C(NC(=O)C3CCNCC3)S2)O1",{"v":2.07,"d":"2.070"},4,2,6]
["S1147","Barasertib (AZD1152-HQPA)","e11","L3800-01","in 10mM DMSO","N/A","N/A","Phase 2","Aurora Kinase","Cell Cycle","Defosbarasertib (AZD1152-HQPA, AZD2811, INH-34, Barasertib-HQPA) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay, ~3700 fold more selective for Aurora B over Aurora A. Phase 1.",507.56,"722544-51-6",{"v":102,"d":"102.00"},200.96,"<1","N/A","http://selleckchem.com/products/AZD1152-HQPA.html","C26H30FN7O3","free base","AZD2811, INH-34, Barasertib-HQPA , Defosbarasertib","CCN(CCO)CCCOC1=CC=C2C(=NC=NC2=C1)NC3=CC(=N[NH]3)CC(=O)NC4=CC=CC(=C4)F",3.493,5,4,13]
["S1148","Docetaxel (RP56976)","f11","L3800-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 2","Microtubule Associated","Cytoskeletal Signaling","Docetaxel (RP56976, NSC 628503), an analog of paclitaxel, is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules.",807.88,"114977-28-5",{"v":100,"d":"100.00"},123.78,"<1","N/A","http://selleckchem.com/products/Docetaxel(Taxotere).html","C43H53NO14","Free Base","NSC 628503,RP56976","CC(=O)OC12COC1CC(O)C3(C)C2C(OC(=O)C4=CC=CC=C4)C5(O)CC(OC(=O)C(O)C(NC(=O)OC(C)(C)C)C6=CC=CC=C6)C(=C(C(O)C3=O)C5(C)C)C",2.586,10,4,13]
["S1150","Paclitaxel (NSC 125973)","g11","L3800-01","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.7;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","ADC Cytotoxin,Antineoplastic and Immunosuppressive Antibiotics,Autophagy,Microtubule Associated","Cytoskeletal Signaling","Paclitaxel (NSC 125973, PTX, Taxol, Onxal, Abraxane) is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.",853.91,"33069-62-4",{"v":171,"d":"171.00"},200.26,"<1","N/A","http://selleckchem.com/products/Paclitaxel(Taxol).html","C47H51NO14","free base","PTX, Taxol, Onxal, Abraxane,NSC 125973","CC(=O)OC1C(=O)C2(C)C(O)CC3OCC3(OC(C)=O)C2C(OC(=O)C4=CC=CC=C4)C5(O)CC(OC(=O)C(O)C(NC(=O)C6=CC=CC=C6)C7=CC=CC=C7)C(=C1C5(C)C)C",3.055,11,3,14]
["S1152","PLX-4720","h11","L3800-01","in 10mM DMSO","N/A","N/A","Phase 1","Raf","MAPK","PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity for B-RafV600E than wild-type B-Raf.",413.83,"918505-84-7",{"v":83,"d":"83.00"},200.57,"<1","N/A","http://selleckchem.com/products/PLX-4720.html","C17H14ClF2N3O3S","free base","N/A","CCC[S](=O)(=O)NC1=CC=C(F)C(=C1F)C(=O)C2=C[NH]C3=NC=C(Cl)C=C23",3.435,4,2,6]
["S1153","Roscovitine (CYC202)","a2","L3800-02","in 10mM DMSO","N/A","N/A","Phase 2","CDK","Cell Cycle","Roscovitine (CYC202, Seliciclib, R-roscovitine) is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM in cell-free assays. It shows little effect on CDK4/6. Phase 2.",354.45,"186692-46-6",{"v":71,"d":"71.00"},200.31,"<1","N/A","http://selleckchem.com/products/Roscovitine.html","C19H26N6O","free base","Seliciclib, R-roscovitine","CCC(CO)NC1=NC(=C2N=C[N](C(C)C)C2=N1)NCC3=CC=CC=C3",{"v":3.32,"d":"3.320"},3,3,8]
["S1156","Capecitabine (RO 09-1978)","b2","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,DNA/RNA Synthesis","DNA Damage/DNA Repair","Capecitabine (RO 09-1978) is a tumor-selective fluoropyrimidine carbamate, which achieves higher intratumoral 5-FU level with lower toxicity than 5-FU. Capecitabine treatment of HCT-15 cells causes condensation of DNA and induces apoptosis.",359.35,"154361-50-9",{"v":72,"d":"72.00"},200.36,{"v":6,"d":"6.00"},{"v":16.7,"d":"16.70"},"http://selleckchem.com/products/Capecitabine(Xeloda).html","C15H22FN3O6","free base","RO 09-1978","CCCCCOC(=O)NC1=NC(=O)N(C=C1F)C2OC(C)C(O)C2O",{"v":0.82,"d":"0.820"},5,3,7]
["S1157","Delanzomib (CEP-18770)","c2","L3800-02","in 10mM DMSO","N/A","N/A","Phase 2","Proteasome","Proteases","Delanzomib (CEP-18770) is an orally active inhibitor of the chymotrypsin-like activity of proteasome with IC50 of 3.8 nM, with only marginal inhibition of the tryptic and peptidylglutamyl activities of the proteosome. Phase 1/2.",413.28,"847499-27-8",{"v":83,"d":"83.00"},200.83,"<1","N/A","http://selleckchem.com/products/cep-18770.html","C21H28BN3O5","free base","N/A","CC(C)C(CNC(=O)C(NC(=O)C1=NC(=CC=C1)C2=CC=CC=C2)C(C)O)B(O)O",2.646,3,3,9]
["S1158","MK-8245","d2","L3800-02","in 10mM DMSO","N/A","N/A","Phase 2","SCD","Metabolism","MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy. Phase 2.",467.25,"1030612-90-8",{"v":93,"d":"93.00"},199.04,"<1","N/A","http://selleckchem.com/products/mk-8245.html","C17H16BrFN6O4","free base","N/A","OC(=O)C[N]1N=NC(=N1)C2=CC(=NO2)N3CCC(CC3)OC4=CC(=CC=C4Br)F",2.991,7,0,6]
["S1159","Ganetespib (STA-9090)","e2","L3800-02","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,HSP (HSP90)","Cytoskeletal Signaling","Ganetespib (STA-9090) is an HSP90 inhibitor with IC50 of 4 nM in OSA 8 cells, induces apoptosis of OSA cells while normal osteoblasts are not affected; active metabolite of STA-1474. Phase 3.",{"v":364.4,"d":"364.40"},"888216-25-9",{"v":40,"d":"40.00"},109.77,"<1","N/A","http://selleckchem.com/products/ganetespib-sta-9090.html","C20H20N4O3","free base","N/A","CC(C)C1=C(O)C=C(O)C(=C1)C2=NNC(=O)N2C3=CC4=C(C=C3)[N](C)C=C4",3.866,2,3,3]
["S1162","Pretomanid (PA-824)","f2","L3800-02","in 10mM DMSO","N/A","N/A","Phase 3","Bacterial","Microbiology","PA-824 is an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM.Phase 2.",359.26,"187235-37-6",{"v":72,"d":"72.00"},200.41,"<1","N/A","http://selleckchem.com/products/pa-824.html","C14H12F3N3O5","free base","N/A","[O-][N+](=O)C1=C[N]2CC(COC2=N1)OCC3=CC=C(OC(F)(F)F)C=C3",4.301,4,0,6]
["S1163","Onalespib (AT13387)","g2","L3800-02","in 10mM DMSO","N/A","N/A","Phase 2","HSP (HSP90)","Cytoskeletal Signaling","Onalespib (AT13387) is a selective potent Hsp90 inhibitor with IC50 of 18 nM in A375 cells, displays a long duration of anti-tumor activity. Phase 2.",409.52,"912999-49-6",{"v":25,"d":"25.00"},61.05,"<1","N/A","http://selleckchem.com/products/at13387.html","C24H31N3O3","free base","N/A","CC(C)C1=C(O)C=C(O)C(=C1)C(=O)N2CC3=C(C2)C=C(CN4CCN(C)CC4)C=C3",3.322,1,2,4]
["S1164","Lenvatinib (E7080)","h2","L3800-02","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","c-Kit,c-RET,FGFR,PDGFR,VEGFR","Protein Tyrosine Kinase","Lenvatinib (E7080) is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β in cell-free assays. Lenvatinib (E7080) also inhibits FGFR1-4, PDGFR, Kit (c-Kit), RET (c-RET), and shows potent antitumor activities. Phase 3.",426.85,"417716-92-8",{"v":40,"d":"40.00"},93.71,"<1","N/A","http://selleckchem.com/products/E7080.html","C21H19ClN4O4","free base","N/A","COC1=C(C=C2C(=CC=NC2=C1)OC3=CC(=C(NC(=O)NC4CC4)C=C3)Cl)C(N)=O",2.832,5,3,6]
["S1165","ABT-751 (E7010)","a3","L3800-02","in 10mM DMSO","N/A","N/A","Phase 2","Microtubule Associated","Cytoskeletal Signaling","ABT-751 (E7010) binds to the colchicine site on β-tubulin and inhibits polymerization of microtubules, not a substrate for the MDR transporter and is active against cell lines resistant to vincristine, doxorubicin, and cisplatin. Phase 1/2.",371.41,"141430-65-1",{"v":74,"d":"74.00"},199.24,"<1","N/A","http://selleckchem.com/products/ABT-751.html","C18H17N3O4S","free base","N/A","COC1=CC=C(C=C1)[S](=O)(=O)NC2=C(NC3=CC=C(O)C=C3)N=CC=C2",2.997,4,3,6]
["S1168","Valproic Acid (NSC 93819) sodium salt","b3","L3800-02","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,GABA Receptor,HDAC,Mitophagy,Notch,PGC-1α","Neuronal Signaling","Valproic Acid sodium salt (NSC 93819, Sodium valproate) is a HDAC inhibitor by selectively inducing proteasomal degradation of HDAC2, used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. Valproic acid induces Notch1 signaling in small cell lung cancer (SCLC) cells. Valproic acid is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α.",166.19,"1069-66-5",{"v":33,"d":"33.00"},198.57,{"v":33,"d":"33.00"},198.57,"http://selleckchem.com/products/Sodium-valproate.html","C8H15NaO2","Sodium salt","Sodium valproate,NSC 93819,2-Propylpentanoic Acid","CCCC(CCC)C(=O)O[Na]",1.275,0,0,5]
["S1171","CYC116","c3","L3800-02","in 10mM DMSO","N/A","N/A","Phase 1","Aurora Kinase,VEGFR","Cell Cycle","CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt/PKB, PKC, no effect on GSK-3α/β, CK2, Plk1 and SAPK2A. Phase 1.",368.46,"693228-63-6",{"v":24,"d":"24.00"},65.14,"<1","N/A","http://selleckchem.com/products/CYC116.html","C18H20N6OS","free base","N/A","CC1=C(SC(=N1)N)C2=NC(=NC=C2)NC3=CC=C(C=C3)N4CCOCC4",2.743,4,2,4]
["S1172","Serdemetan (JNJ-26854165)","d3","L3800-02","in 10mM DMSO","N/A","N/A","Phase 1","E3 Ligase ,p53","Apoptosis","Serdemetan (JNJ-26854165) acts as a HDM2 ubiquitin ligase antagonist and also induces early apoptosis in p53 wild-type cells, inhibits cellular proliferation followed by delayed apoptosis in the absence of functional p53. Phase 1.",328.41,"881202-45-5",{"v":66,"d":"66.00"},200.97,"<1","N/A","http://selleckchem.com/products/JNJ-26854165.html","C21H20N4","free base","N/A","C(CC1=C[NH]C2=CC=CC=C12)NC3=CC=C(NC4=CC=NC=C4)C=C3",4.236,1,3,6]
["S1175","BIIB021","e3","L3800-02","in 10mM DMSO","N/A","N/A","Phase 2","HSP (HSP90)","Cytoskeletal Signaling","BIIB021 (CNF2024) is an orally available, fully synthetic small-molecule inhibitor of HSP90 with Ki and EC50 of 1.7 nM and 38 nM, respectively. Phase 2.",318.76,"848695-25-0",{"v":64,"d":"64.00"},200.78,"<1","N/A","http://selleckchem.com/products/BIIB021.html","C14H15ClN6O","free base","CNF2024","COC1=C(C)C=NC(=C1C)C[N]2C=NC3=C(Cl)N=C(N)N=C23",2.223,5,1,3]
["S1176","Plinabulin (NPI-2358)","f3","L3800-02","in 10mM DMSO","N/A","N/A","Phase 3","Microtubule Associated,VDA","Angiogenesis","Plinabulin (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing with IC50 of 9.8~18 nM in tumor cells. Phase 1/2.",336.39,"714272-27-2",{"v":54,"d":"54.00"},160.53,"<1","N/A","http://selleckchem.com/products/NPI-2358.html","C19H20N4O2","free base","N/A","CC(C)(C)C1=C(/C=C/2NC(=O)C(/NC2=O)=C/C3=CC=CC=C3)N=C[NH]1",1.921,3,3,3]
["S1178","Regorafenib (BAY 73-4506)","g3","L3800-02","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","EP9.8","Marketed","Autophagy,c-Kit,c-RET,PDGFR,Raf,VEGFR","Protein Tyrosine Kinase","Regorafenib (BAY 73-4506,Fluoro-Sorafenib, Resihance, Stivarga) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively. Regorafenib induces autophagy.",482.82,"755037-03-7",{"v":97,"d":"97.00"},{"v":200.9,"d":"200.90"},"<1","N/A","http://selleckchem.com/products/BAY-73-4506.html","C21H15ClF4N4O3","free base","Fluoro-Sorafenib, Resihance, Stivarga,BAY 73-4506","CNC(=O)C1=CC(=CC=N1)OC2=CC(=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2)F",4.381,4,3,6]
["S1181","ENMD-2076","h3","L3800-02","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,Aurora Kinase,CSF-1R,FGFR,FLT3,PDGFR,Src,VEGFR","Angiogenesis","ENMD-2076 has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to RET, SRC, NTRK1/TRKA, CSF1R/FMS, VEGFR2/KDR, FGFR and PDGFRα. ENMD-2076 inhibits the growth of a wide range of human solid tumor and hematopoietic cancer cell lines with IC50 from 0.025 to 0.7 μM, which induces apoptosis and G2/M phase arrest. Phase 2.",375.47,"934353-76-1",{"v":105,"d":"105.00"},279.65,{"v":1,"d":"1.00"},2.66,"http://selleckchem.com/products/enmd-2076.html","C21H25N7","Tartaric Acid","N/A","CN1CCN(CC1)C2=CC(=NC(=N2)\\C=C\\C3=CC=CC=C3)NC4=N[NH]C(=C4)C",4.015,3,2,5]
["S1183","Danoprevir (ITMN-191)","a4","L3800-02","in 10mM DMSO","CFDA","N/A","Marketed","COVID-19,HCV Protease","Proteases","Danoprevir (ITMN-191, RG7227) is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. Phase 2.",731.83,"850876-88-9",{"v":144,"d":"144.00"},196.77,"<1","N/A","http://selleckchem.com/products/Danoprevir.html","C35H46FN5O9S","free base","RG7227","CC(C)(C)OC(=O)NC1CCCCC\\C=C/C2CC2(NC(=O)C3CC(CN3C1=O)OC(=O)N4CC5=C(C4)C(=CC=C5)F)C(=O)N[S](=O)(=O)C6CC6",2.922,9,3,8]
["S1185","Ritonavir (ABT-538)","b4","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,COVID-19,HIV Protease,P450 (e.g. CYP17)","Proteases","Ritonavir (ABT-538, A 84538, RTV, Norvir, Norvir Softgel) is a Cytochrome P450 3A and Protease Inhibitor; Also inhibits Cytochrome P450 2D6, P-Glycoprotein and induces Cytochrome P450 2C19, Cytochrome P450 1A2, Cytochrome P450 2C9, Cytochrome P450 2B6 and UDP Glucuronosyltransferases. Ritonavir induces apoptosis.",720.94,"155213-67-5",{"v":100,"d":"100.00"},138.71,"<1","N/A","http://selleckchem.com/products/Ritonavir.html","C37H48N6O5S2","free base","ABT-538,A 84538, RTV, Norvir, Norvir Softgel","CC(C)C(NC(=O)N(C)CC1=CSC(=N1)C(C)C)C(=O)NC(CC(O)C(CC2=CC=CC=C2)NC(=O)OCC3=CN=CS3)CC4=CC=CC=C4",4.978,6,4,18]
["S1188","Anastrozole (ZD-1033)","c4","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.3;BP2019;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Aromatase","Endocrinology & Hormones","Anastrozole (Arimidex,ZD-1033) is a third-generation nonsteroidal selective aromatase inhibitor. It may offer greater selectivity compared with other aromatase inhibitors, being without any intrinsic endocrine effects and with no apparent effect on the synthesis of adrenal steroids.",293.37,"120511-73-1",{"v":59,"d":"59.00"},201.11,"<1","N/A","http://selleckchem.com/products/Anastrozole.html","C17H19N5","free base","Arimidex,ZD-1033","CC(C)(C#N)C1=CC(=CC(=C1)C[N]2C=NC=N2)C(C)(C)C#N",2.965,2,0,4]
["S1189","Aprepitant (MK-0869)","d4","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","CSF-1R,HIV,Interleukins,Neurokinin Receptor,TNF-alpha","Neuronal Signaling","Aprepitant (MK-0869, L-754030, Emend) is a potent and selective neurokinin-1 receptor antagonist with IC50 of 0.1 nM. Aprepitant reduces levels of pro-inflammatory cytokines including G-CSF, IL-6, IL-8 and TNFα. Aprepitant inhibits HIV infection of human macrophages.",534.43,"170729-80-3",{"v":107,"d":"107.00"},200.21,"<1","N/A","http://selleckchem.com/products/Aprepitant.html","C23H21F7N4O3","free base","MK-0869, L-754030, Emend","CC(OC1OCCN(CC2=NNC(=O)N2)C1C3=CC=C(F)C=C3)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F",4.635,4,2,8]
["S1190","Bicalutamide (ICI-176334)","e4","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Androgen Receptor,Autophagy","Endocrinology & Hormones","Bicalutamide (ICI-176334) is an androgen receptor (AR) antagonist with IC50 of 0.16 μM in LNCaP/AR(cs)cell line. Bicalutamide promotes autophagy.",430.37,"90357-06-5",{"v":86,"d":"86.00"},199.83,"<1","N/A","http://selleckchem.com/products/Bicalutamide(Casodex).html","C18H14F4N2O4S","free base","ICI-176334","CC(O)(C[S](=O)(=O)C1=CC=C(F)C=C1)C(=O)NC2=CC=C(C#N)C(=C2)C(F)(F)F",2.926,3,1,6]
["S1191","Fulvestrant (ICI-182780)","f4","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","USP42-NF37;BP2019;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,Estrogen/progestogen Receptor","Endocrinology & Hormones","Fulvestrant (ICI-182780, ZD 9238, ZM 182780) is an estrogen receptor (ER) antagonist with IC50 of 0.94 nM in a cell-free assay. Fulvestrant also induces autophagy and apoptosis and has antitumor activity.",606.77,"129453-61-8",{"v":100,"d":"100.00"},164.81,"<1","N/A","http://selleckchem.com/products/Fulvestrant.html","C32H47F5O3S","free base","ICI-182780, ZD 9238, ZM 182780","CC12CCC3C(C(CCCCCCCCC[S](=O)CCCC(F)(F)C(F)(F)F)CC4=C3C=CC(=C4)O)C1CCC2O",8.437,1,2,15]
["S1192","Raltitrexed","g4","L3800-02","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","Marketed","DNA/RNA Synthesis,Thymidylate Synthase","DNA Damage/DNA Repair","Raltitrexed (ZD-1694) is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth.",458.49,"112887-68-0",{"v":91,"d":"91.00"},198.48,"<1","N/A","http://selleckchem.com/products/Raltitrexed.html","C21H22N4O6S","free base","ZD-1694, ICI-D1694, D1694","CN(CC1=CC2=C(C=C1)N=C(C)NC2=O)C3=CC=C(S3)C(=O)NC(CCC(O)=O)C(O)=O",1.528,5,2,9]
["S1193","Thalidomide (K17)","h4","L3800-02","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA","USP42-NF37 ;Martindale:The Extra Pharmacopoeia","Marketed","E3 Ligase ,E3 ligase Ligand,TNF-alpha","Ubiquitin","Thalidomide (K17) was introduced as a sedative drug, immunomodulatory agent and also is investigated for treating symptoms of many cancers. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1.",258.23,"50-35-1",{"v":51,"d":"51.00"},{"v":197.5,"d":"197.50"},"<1","N/A","http://selleckchem.com/products/Thalidomide.html","C13H10N2O4","free base","K17","O=C1CCC(N2C(=O)C3=C(C=CC=C3)C2=O)C(=O)N1",0.097,4,1,1]
["S1194","CUDC-101","a5","L3800-02","in 10mM DMSO","N/A","N/A","Phase 1","EGFR,HDAC,HER2","Epigenetics","CUDC-101 is a potent multi-targeted inhibitor against HDAC, EGFR and HER2 with IC50 of 4.4 nM, 2.4 nM, and 15.7 nM, and inhibits class I/II HDACs, but not class III, Sir-type HDACs. Phase 1.",434.49,"1012054-59-9",{"v":20,"d":"20.00"},46.03,"<1","N/A","http://selleckchem.com/products/CUDC-101.html","C24H26N4O4","free base","N/A","COC1=CC2=C(C=C1OCCCCCCC(=O)NO)C(=NC=N2)NC3=CC(=CC=C3)C#C",5.376,5,2,11]
["S1196","Exemestane (FCE 24304)","b5","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Aromatase","Endocrinology & Hormones","Exemestane (Aromasin,FCE24304, PNU155971,EXE) is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively.",{"v":296.4,"d":"296.40"},"107868-30-4",{"v":54,"d":"54.00"},182.19,"<1","N/A","http://selleckchem.com/products/Exemestane.html","C20H24O2","free base","Aromasin,FCE24304, PNU155971,EXE","CC12CCC3C(CC(=C)C4=CC(=O)C=CC34C)C1CCC2=O",3.606,2,0,0]
["S1197","Finasteride","c5","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","5-alpha Reductase","Endocrinology & Hormones","Finasteride (MK-906) is a potent, reversible inhibitor of the rat type 1 5 alpha-reductase with Ki of 10.2 nM, used in the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB).",372.54,"98319-26-7",{"v":75,"d":"75.00"},201.32,"<1","N/A","http://selleckchem.com/products/Finasteride.html","C23H36N2O2","free base","MK-906","CC(C)(C)NC(=O)C1CCC2C3CCC4NC(=O)C=CC4(C)C3CCC12C",3.174,2,2,2]
["S1199","Cladribine (RWJ 26251)","d5","L3800-02","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;All compounds are not protected by patents","Marketed","Adenosine Deaminase,DNA/RNA Synthesis","Neuronal Signaling","Cladribine (RWJ 26251, Leustatin, 2-CdA, 2-chlorodeoxyadenosine, 2-Chloro-2′-deoxyadenosine, CldAdo, Jk 6251, NSC 105014) is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43 μM, 0.75 μM, and 0.18 μM, respectively.",285.69,"4291-63-8",{"v":57,"d":"57.00"},199.52,"<1","N/A","http://selleckchem.com/products/Cladribine.html","C10H12ClN5O3","free base","Leustatin,2-CdA,2-Chloro-2′-deoxyadenosine,CldAdo,Jk 6251,NSC 105014,RWJ 26251","NC1=NC(=NC2=C1N=C[N]2C3CC(O)C(CO)O3)Cl",-0.259,4,3,2]
["S1200","Decitabine (NSC 127716)","e5","L3800-02","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,DNA Methyltransferase,Nucleoside Analog/Antimetabolite","Epigenetics","Decitabine (Deoxycytidine, Dacogen, 5-aza-2'-deoxycytidine, 5-AZA-dC, 5-aza-CdR,NSC 127716) is a DNA methyltransferase inhibitor, incorporating into DNA and resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. It is used to treat myelodysplastic syndrome (MDS). Decitabine induces cell cycle arrest and apoptosis in various cancer cell lines.",228.21,"2353-33-5",{"v":45,"d":"45.00"},197.19,{"v":10,"d":"10.00"},43.82,"http://selleckchem.com/products/Decitabine.html","C8H12N4O4","free base","Deoxycytidine, Dacogen, 5-aza-2'-deoxycytidine, 5-AZA-dC, 5-aza-CdR,NSC 127716","NC1=NC(=O)N(C=N1)C2CC(O)C(CO)O2",-1.093,4,3,2]
["S1201","Dimesna","f5","L3800-02","in 10mM DMSO","N/A","N/A","Phase 3","Others","Others","Dimesna (BNP-7787) is an uroprotective agent used to decrease urotoxicity.",326.34,"16208-51-8",{"v":65,"d":"65.00"},199.18,{"v":65,"d":"65.00"},199.18,"http://selleckchem.com/products/Dimesna.html","C4H8Na2O6S4","Disodium salt","BNP-7787","[Na+].[Na+].[O-][S](=O)(=O)CCSSCC[S]([O-])(=O)=O",-4.295,0,0,7]
["S1202","Dutasteride","g5","L3800-02","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","5-alpha Reductase","Endocrinology & Hormones","Dutasteride (GI198745, GG-745) is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT).",528.53,"164656-23-9",{"v":62,"d":"62.00"},117.31,"<1","N/A","http://selleckchem.com/products/Dutasteride.html","C27H30F6N2O2","free base","GI198745, GG-745","CC12CCC3C(CCC4NC(=O)C=CC34C)C1CCC2C(=O)NC5=CC(=CC=C5C(F)(F)F)C(F)(F)F",5.703,2,2,4]
["S1204","Melatonin (NSC 113928)","h5","L3800-02","in 10mM DMSO","DMF,EMA,HMA,NDC","USP42-NF37;BP2019;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,ATF/CREB & c-Fos/c-Jun,Autophagy,COX,Mitophagy,MT Receptor","GPCR & G Protein","Melatonin (NSC 113928, NSC 56423, N-Acetyl-5-methoxytryptamine,MT) is a MT receptor agonist, used as a dietary supplement. Melatonin is a selective ATF-6 inhibitor and downregulates COX-2. Melatonin enhances mitophagy and regulates the homeostasis of apoptosis and autophagy.",232.28,"73-31-4",{"v":47,"d":"47.00"},202.34,"<1","N/A","http://selleckchem.com/products/Melatonin.html","C13H16N2O2","free base","NSC 56423, N-Acetyl-5-methoxytryptamine,NSC 113928,MT","COC1=CC2=C([NH]C=C2CCNC(C)=O)C=C1",1.555,2,2,4]
["S1206","Bisoprolol fumarate","a6","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Bisoprolol fumarate (EMD33512) is a selective type β1 adrenergic receptor blocker.",441.52,"104344-23-2",{"v":88,"d":"88.00"},199.31,{"v":88,"d":"88.00"},199.31,"http://selleckchem.com/products/Bisoprolol-Fumarate.html","C22H35NO8","fumarate","EMD33512","CC(C)NCC(O)COC1=CC=C(COCCOC(C)C)C=C1.OC(=O)\\C=C\\C(O)=O",-0.635,5,2,14]
["S1207","Tivozanib (AV-951)","b6","L3800-02","in 10mM DMSO","EMA","N/A","Marketed","c-Kit,PDGFR,VEGFR","Protein Tyrosine Kinase","Tivozanib (AV-951, KRN-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 30 nM/6.5 nM/15 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met, EGFR and IGF-1R. Phase 3.",454.86,"475108-18-0",{"v":20,"d":"20.00"},43.97,"<1","N/A","http://selleckchem.com/products/AV-951.html","C22H19ClN4O5","free base","KRN-951","COC1=CC2=C(C=C1OC)C(=CC=N2)OC3=CC=C(NC(=O)NC4=NOC(=C4)C)C(=C3)Cl",4.039,7,2,6]
["S1208","Doxorubicin (Adriamycin) HCl","c6","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Registered","ADC Cytotoxin,AMPK,Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,HIV,Mitophagy,Topoisomerase","DNA Damage/DNA Repair","Doxorubicin (Adriamycin, NSC 123127, DOX, Hydroxydaunorubicin) HCl is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage, mitophagy and apoptosis in tumor cells. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.",579.98,"25316-40-9",{"v":100,"d":"100.00"},172.42,{"v":20,"d":"20.00"},34.48,"http://selleckchem.com/products/Adriamycin.html","C27H29NO11.HCl","Hydrochloride","NSC 123127, DOX, Doxorubicin hydrochloride, Hydroxydaunorubicin HCl,Adriamycin HCl","Cl.COC1=C2C(=O)C3=C(C(=C4CC(O)(CC(OC5CC(N)C(O)C(C)O5)C4=C3O)C(=O)CO)O)C(=O)C2=CC=C1",0.338,6,5,5]
["S1209","Fluorouracil (5-Fluorouracil, 5-FU)","d6","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.2;BP2019;KP Ⅹ;Ph.Int_6th;JP16;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,DNA/RNA Synthesis,HIV,Nucleoside Analog/Antimetabolite,Thymidylate Synthase","DNA Damage/DNA Repair","Fluorouracil (5-Fluorouracil, 5-FU, NSC 19893) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV.",130.08,"51-21-8",{"v":26,"d":"26.00"},199.88,"<1","N/A","http://selleckchem.com/products/Adrucil(Fluorouracil).html","C4H3FN2O2","free base","NSC 19893,5-Fluorouracil, 5-FU","FC1=CNC(=O)NC1=O",-1.102,2,2,0]
["S1210","Methotrexate (CL-14377)","e6","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","ADC Cytotoxin,DHFR","Metabolism","Methotrexate (CL14377, MTX, NCI-C04671, Amethopterin, WR19039, abitrexate), analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH. Methotrexate (MTX) induces apoptosis.",454.44,"59-05-2",{"v":90,"d":"90.00"},198.05,"<1","N/A","http://selleckchem.com/products/Abitrexate.html","C20H22N8O5","free base","NCI-C04671, Amethopterin, CL14377, WR19039, abitrexate","CN(CC1=NC2=C(N)N=C(N)N=C2N=C1)C3=CC=C(C=C3)C(=O)NC(CCC(O)=O)C(O)=O",0.114,7,3,9]
["S1212","Bendamustine (SDX105) HCl","f6","L3800-02","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","DNA/RNA Synthesis","DNA Damage/DNA Repair","Bendamustine (SDX-105, Cytostasane) HCl is a DNA-damaging agent with IC50 of 50 μM in cell-free assay.",394.72,"3543-75-7",{"v":78,"d":"78.00"},197.61,{"v":2,"d":"2.00"},5.07,"http://selleckchem.com/products/Bendamustine-Hydrochloride.html","C16H21Cl2N3O2.HCl","Hydrochloride","Cytostasane HCl","Cl.C[N]1C(=NC2=CC(=CC=C12)N(CCCl)CCCl)CCCC(O)=O",3.988,2,0,9]
["S1213","Nelarabine","g6","L3800-02","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","DNA/RNA Synthesis","DNA Damage/DNA Repair","Nelarabine (506U78,Arranon) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.",297.27,"121032-29-9",{"v":60,"d":"60.00"},201.84,{"v":3,"d":"3.00"},10.09,"http://selleckchem.com/products/Arranon.html","C11H15N5O5","free base","506U78,Arranon","COC1=NC(=NC2=C1N=C[N]2C3OC(CO)C(O)C3O)N",-1.376,5,4,3]
["S1214","Bleomycin (NSC125066) sulfate","h6","L3800-02","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,BP2017,JP17","N/A","Antineoplastic and Immunosuppressive Antibiotics,DNA/RNA Synthesis,Selection Antibiotics for Transfected Cell","DNA Damage/DNA Repair","Bleomycin Sulfate (Blenoxane,NSC125066) is a glycopeptide antibiotic and an anticancer agent for squamous cell carcinomas (SCC) with IC50 of 4 nM in UT-SCC-19A cells.",1512.62,"9041-93-4",{"v":100,"d":"100.00"},{"v":66,"d":"66.00"},"N/A","N/A","http://www.selleckchem.com/products/Bleomycin-sulfate.html","C55H85N17O25S4","Sulfate","Blenoxane,NSC125066","CC(O)C(NC(=O)C(C)C(O)C(C)NC(=O)C(NC(=O)C1=C(C)C(=NC(=N1)C(CC(N)=O)NCC(N)C(N)=O)N)C(OC2OC(CO)C(O)C(O)C2OC3OC(CO)C(O)C(OC(N)=O)C3O)C4=C[NH]C=N4)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C.O[S]([O-])(=O)=O","N/A","N/A","N/A","N/A"]
["S1218","Clofarabine","a7","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,DNA/RNA Synthesis,RNR","DNA Damage/DNA Repair","Clofarabine (Clolar) inhibits the enzymatic activities of ribonucleotide reductase (RNR) (IC50 = 65 nM) and DNA polymerase. Clofarabine induces autophagy and apoptosis.",303.68,"123318-82-1",{"v":60,"d":"60.00"},197.58,"<1","N/A","http://selleckchem.com/products/Clofarabine.html","C10H11ClFN5O3","free base","Clolar","NC1=C2N=C[N](C3OC(CO)C(O)C3F)C2=NC(=N1)Cl",-0.085,4,3,2]
["S1220","OSI-930","b7","L3800-02","in 10mM DMSO","N/A","N/A","Phase 1","c-Kit,CSF-1R,VEGFR","Protein Tyrosine Kinase","OSI-930 is a potent inhibitor of Kit (c-Kit), KDR and CSF-1R with IC50 of 80 nM, 9 nM and 15 nM, respectively; also potent to Flt-1, c-Raf and Lck and low activity against PDGFRα/β, Flt-3 and Abl. Phase 1.",443.44,"728033-96-3",{"v":89,"d":"89.00"},{"v":200.7,"d":"200.70"},"<1","N/A","http://selleckchem.com/products/OSI-930.html","C22H16F3N3O2S","free base","N/A","FC(F)(F)OC1=CC=C(NC(=O)C2=C(NCC3=CC=NC4=CC=CC=C34)C=CS2)C=C1",6.266,3,2,7]
["S1221","Dacarbazine (NSC-45388)","c7","L3800-02","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,Ph.Int_6th,BP2017","Phase 1/2","Antineoplastic and Immunosuppressive Antibiotics,DNA/RNA Synthesis","DNA Damage/DNA Repair","Dacarbazine (NSC-45388, DTIC-Dome, Imidazole Carboxamide) is a triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis; used in the treatment of various cancers.",182.18,"4342-03-4",{"v":12,"d":"12.00"},65.87,{"v":2,"d":"2.00"},10.98,"http://selleckchem.com/products/Dacarbazine.html","C6H10N6O","free base","DTIC-Dome, Imidazole Carboxamide,NSC-45388","CN(C)N=NC1=C(N=C[NH]1)C(N)=O",-0.344,4,2,3]
["S1222","Dexrazoxane HCl (ICRF-187)","d7","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Topoisomerase","DNA Damage/DNA Repair","Dexrazoxane HCl (ADR-529,Totect, ICRF-187, Zinecard, Cardioxane) is an intracellular iron chelator, which decreases the formation of superoxide radicals, used as a cardioprotective agent; also an inhibitor of topoisomerase II",304.73,"149003-01-0",{"v":60,"d":"60.00"},{"v":196.9,"d":"196.90"},{"v":60,"d":"60.00"},{"v":196.9,"d":"196.90"},"http://selleckchem.com/products/Dexrazoxane-Hydrochloride.html","C11H16N4O4.HCl","Hydrochloride","ADR-529,Totect, ICRF-187, Zinecard, Cardioxane","Cl.CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2",-1.722,4,2,3]
["S1223","Epirubicin (IMI 28) HCl","e7","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;Martindale:The Extra Pharmacopoeia","Phase 1/2","Apoptosis related,Topoisomerase","DNA Damage/DNA Repair","Epirubicin HCl (Ellence, Pharmorubicin, Epirubicin Ebewe,IMI 28, NSC 256942, 4'-epidoxorubicin,Epirubicin hydrochloride), a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. Epirubicin induces apoptosis.",579.98,"56390-09-1",{"v":100,"d":"100.00"},172.42,{"v":100,"d":"100.00"},172.42,"http://selleckchem.com/products/Ellence.html","C27H29NO11.HCl","Hydrochloride","Ellence, Pharmorubicin, Epirubicin Ebewe,IMI 28, NSC 256942, 4'-epidoxorubicin,Epirubicin hydrochloride","Cl.COC1=C2C(=O)C3=C(C(=C4CC(O)(CC(OC5CC(N)C(O)C(C)O5)C4=C3O)C(=O)CO)O)C(=O)C2=CC=C1",0.338,6,5,5]
["S1225","Etoposide (VP-16)","f7","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.2;BP2019;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,Autophagy,Mitophagy,Topoisomerase","DNA Damage/DNA Repair","Etoposide (VP-16213,Vepesid,VP-16) is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II  inhibition activity. Etoposide induces autophagy, mitophagy and apoptosis.",588.56,"33419-42-0",{"v":100,"d":"100.00"},169.91,"<1","N/A","http://selleckchem.com/products/Etopophos.html","C29H32O13","free base","VP-16213,Vepesid,VP-16","COC1=CC(=CC(=C1O)OC)C2C3C(COC3=O)C(OC4OC5COC(C)OC5C(O)C4O)C6=C2C=C7OCOC7=C6",0.935,10,3,5]
["S1227","Raloxifene HCl","g7","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Raloxifene (LY156758, Keoxifene) HCl is a selective and orally active estrogen receptor modulator (SERM), which inhibits human cytosolic aldehyde oxidase-catalyzed phthalazine oxidation activity with IC50 of 5.7 nM.",510.04,"82640-04-8",{"v":100,"d":"100.00"},196.06,"<1","N/A","http://selleckchem.com/products/Evista.html","C28H27NO4S.HCl","Hydrochloride","LY156758 (Keoxifene) HCl","Cl.OC1=CC=C(C=C1)C2=C(C(=O)C3=CC=C(OCCN4CCCCC4)C=C3)C5=C(S2)C=C(O)C=C5",6.843,2,2,7]
["S1229","Fludarabine Phosphate","h7","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","DNA/RNA Synthesis","DNA Damage/DNA Repair","Fludarabine Phosphate (F-ara-A, NSC 312887) is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis.",365.21,"75607-67-9",{"v":73,"d":"73.00"},199.88,{"v":2,"d":"2.00"},5.48,"http://selleckchem.com/products/Fludara.html","C10H13FN5O7P","Phosphate","F-ara-A (NSC 312887) Phosphate","NC1=NC(=NC2=C1N=C[N]2C3OC(CO[P](O)(O)=O)C(O)C3O)F",-1.384,5,3,4]
["S1230","Flavopiridol (L86-8275)","a8","L3800-02","in 10mM DMSO","N/A","N/A","Phase 2","Autophagy,CDK,HIV","Cell Cycle","Flavopiridol (L86-8275, Alvocidib, NSC 649890, HMR-1275) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4, CDK6, and CDK9 with IC50 values in the 20-100 nM range. It is more selective for CDK1, 2, 4, 6, 9 versus CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Flavopiridol induces autophagy and ER stress. Flavopiridol blocks HIV-1 replication. Phase 1/2.",401.84,"146426-40-6",{"v":15,"d":"15.00"},37.33,"<1","N/A","http://selleckchem.com/products/Flavopiridol.html","C21H20ClNO5","Free Base","NSC 649890 HCl, HMR-1275, Alvocidib","CN1CCC(C(O)C1)C2=C3OC(=CC(=O)C3=C(O)C=C2O)C4=C(Cl)C=CC=C4",3.108,2,3,2]
["S1231","Topotecan (NSC609699) HCl","b8","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","EP;USP;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,Topoisomerase","DNA Damage/DNA Repair","Topotecan HCl (Nogitecan HCl, SKFS 104864A,Hycamtin, NSC 609699) is a topoisomerase I inhibitor for MCF-7 Luc cells and DU-145 Luc cells with IC50 of 13 nM and 2 nM in cell-free assays, respectively. Topotecan HCl induces autophagy and apoptosis.",457.91,"119413-54-6",{"v":91,"d":"91.00"},198.73,{"v":91,"d":"91.00"},198.73,"http://selleckchem.com/products/Topotecan-Hydrochloride.html","C23H23N3O5.HCl","Hydrochloride","Nogitecan HCl, SKFS 104864A,Hycamtin, NSC 609699","Cl.CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC(=C(CN(C)C)C5=C4)O)C2=O",1.959,4,1,3]
["S1233","2-Methoxyestradiol (2-MeOE2)","c8","L3800-02","in 10mM DMSO","DMF","N/A","N/A","Apoptosis related,Autophagy,HIF,Microtubule Associated","Angiogenesis","2-Methoxyestradiol (2-MeOE2, NSC 659853, 2-ME2) depolymerizes microtubules and blocks HIF-1α nuclear accumulation and HIF-transcriptional activity. 2-Methoxyestradiol induces both autophagy and apoptosis in various carcinogenic cell lines.",302.41,"362-07-2",{"v":60,"d":"60.00"},198.41,"<1","N/A","http://selleckchem.com/products/2-Methoxyestradiol(2ME2).html","C19H26O3","free base","NSC 659853, 2-ME2","COC1=C(O)C=C2CCC3C(CCC4(C)C(O)CCC34)C2=C1",3.821,1,2,1]
["S1235","Letrozole (CGS 20267)","d8","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;KP Ⅹ;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Aromatase,Autophagy","Endocrinology & Hormones","Letrozole (CGS 20267,Femara, Piroxicam) is a third generation inhibitor of aromatase with IC50 of 0.07-20 nM in cell-free assays.It has no effect on the plasma levels of 17α-OH progesterone, thyroid-stimulating hormone (TSH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), or androstenedione and does not affect normal urine electrolyte excretion or thyroid function in clinical studies. Letrozole induces autophagy.",{"v":285.3,"d":"285.30"},"112809-51-5",{"v":57,"d":"57.00"},199.79,"<1","N/A","http://selleckchem.com/products/Letrozole.html","C17H11N5","free base","CGS 20267,Femara, Piroxicam","N#CC1=CC=C(C=C1)C([N]2C=NC=N2)C3=CC=C(C=C3)C#N",2.749,2,0,3]
["S1237","Temozolomide (CCRG 81045)","e8","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37 ;EP9.4;BP2019;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,DNA/RNA Synthesis","DNA Damage/DNA Repair","Temozolomide (NSC 362856,TMZ,CCRG 81045,Methazolastone,Temodar,Temodal) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosis and exhibits antitumor activity.",194.15,"85622-93-1",{"v":38,"d":"38.00"},195.72,"<1","N/A","http://selleckchem.com/products/Methazolastone.html","C6H6N6O2","free base","NSC 362856,TMZ,CCRG 81045,Methazolastone,Temodar,Temodal","CN1N=NC2=C(N=C[N]2C1=O)C(N)=O",0.052,5,1,1]
["S1238","Tamoxifen (ICI 46474)","f8","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,ATPase,Autophagy,Estrogen/progestogen Receptor,HSP (HSP90)","Angiogenesis","Tamoxifen (ICI 46474, (Z)-Tamoxifen, trans-Tamoxifen) is a selective estrogen receptor modulator (SERM). Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen induces apoptosis.",371.51,"10540-29-1",{"v":74,"d":"74.00"},199.19,"<1","N/A","http://selleckchem.com/products/Nolvadex.html","C26H29NO","Free Base","ICI 46474, (Z)-Tamoxifen, trans-Tamoxifen","CC/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(OCCN(C)C)C=C3.OC(=O)CC(O)(CC(O)=O)C(O)=O",1.966,4,0,13]
["S1241","Vincristine (NSC-67574) sulfate","g8","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,Autophagy,Microtubule Associated","Cytoskeletal Signaling","Vincristine sulfate (NSC-67574, Leurocristine, Oncovin, 22-Oxovincaleukoblastine) is an inhibitor of polymerization of microtubules by binding to tubulin with IC50 of 32 μM in a cell-free assay. Vincristine sulfate induces apoptosis.",923.04,"2068-78-2",{"v":100,"d":"100.00"},108.34,{"v":60,"d":"60.00"},{"v":65,"d":"65.00"},"http://selleckchem.com/products/Vincristine-Sulfate.html","C46H58N4O14S","free base","Leurocristine, Oncovin, NSC-67574, 22-Oxovincaleukoblastine","CCC1(O)CC2CN(CCC3=C([NH]C4=C3C=CC=C4)C(C2)(C(=O)OC)C5=CC6=C(C=C5OC)N(C=O)C7C(O)(C(OC(C)=O)C8(CC)C=CCN9CCC67C89)C(=O)OC)C1.O[S](O)(=O)=O",3.365,8,1,10]
["S1243","Agomelatine (S20098)","h8","L3800-02","in 10mM DMSO","DMF,EMA,HMA,CFDA","Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor","Neuronal Signaling","Agomelatine (Valdoxan, Melitor, Thymanax,S20098) is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.",{"v":243.3,"d":"243.30"},"138112-76-2",{"v":48,"d":"48.00"},197.29,"<1","N/A","http://selleckchem.com/products/Agomelatine.html","C15H17NO2","free base","Valdoxan, Melitor, Thymanax,S20098","COC1=CC2=C(CCNC(C)=O)C=CC=C2C=C1",{"v":2.17,"d":"2.170"},2,1,4]
["S1244","Amuvatinib (MP-470)","a9","L3800-02","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,c-Kit,c-Met,c-RET,FLT3,PDGFR,RAD51","Protein Tyrosine Kinase","Amuvatinib (MP-470, HPK 56) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. Amuvatinib suppresses c-MET and c-RET. Amuvatinib is also active as a DNA repair protein Rad51 inhibitor with antineoplastic activity. Phase 2.",447.51,"850879-09-3",{"v":32,"d":"32.00"},71.51,"<1","N/A","http://selleckchem.com/products/MP-470.html","C23H21N5O3S","free base","HPK 56","S=C(NCC1=CC=C2OCOC2=C1)N3CCN(CC3)C4=NC=NC5=C4OC6=CC=CC=C56",4.867,5,1,5]
["S1245","Latrepirdine 2HCl","b9","L3800-02","in 10mM DMSO","N/A","Martindale the Extra Pharmacopoei","N/A","5-HT Receptor,GluR,Histamine Receptor","Neuronal Signaling","Latrepirdine is an orally active,and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihistamine drug.",392.37,"97657-92-6",{"v":24,"d":"24.00"},61.17,"<1","N/A","http://selleckchem.com/products/Dimebon.html","C21H25N3.2HCl","Dihydrochloride","N/A","Cl.Cl.CN1CCC2=C(C1)C3=C(C=CC(=C3)C)[N]2CCC4=CC=C(C)N=C4",4.769,1,0,3]
["S1247","Leflunomide (HWA486)","c9","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","AhR,Dehydrogenase","Metabolism","Leflunomide (HWA486, RS-34821, SU101, Arava) is a pyrimidine synthesis and protein tyrosine kinase inhibitor belonging to the DMARD, used as an immunosuppressant agent. The active metabolite of Leflunomide is A77 1726, which inhibits dihydroorotate dehydrogenase (DHODH). Leflunomide is also an agonist of the AhR.",270.21,"75706-12-6",{"v":54,"d":"54.00"},199.84,"<1","N/A","http://selleckchem.com/products/Leflunomide.html","C12H9F3N2O2","free base","HWA486, RS-34821, SU101, Arava","CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F",2.156,3,1,3]
["S1250","Enzalutamide (MDV3100)","d9","L3800-02","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Androgen Receptor,Autophagy","Endocrinology & Hormones","Enzalutamide (MDV3100) is an androgen-receptor (AR) antagonist with IC50 of 36 nM in LNCaP cells. Enzalutamide is shown to increase autophagy.",464.44,"915087-33-1",{"v":92,"d":"92.00"},198.09,"<1","N/A","http://selleckchem.com/products/MDV3100.html","C21H16F4N4O2S","free base","MDV3100","CNC(=O)C1=C(F)C=C(C=C1)N2C(=S)N(C(=O)C2(C)C)C3=CC=C(C#N)C(=C3)C(F)(F)F",4.954,2,1,4]
["S1251","Dienogest","e9","L3800-02","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Dienogest (STS 557) is an orally active synthetic progesterone, used for contraception and the treatment of endometriosis.",311.42,"65928-58-7",{"v":62,"d":"62.00"},199.09,"<1","N/A","http://selleckchem.com/products/Dienogest.html","C20H25NO2","free base","STS 557","CC12CCC3=C4CCC(=O)C=C4CCC3C1CCC2(O)CC#N",3.046,1,0,1]
["S1252","Entecavir Hydrate","f9","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.7;BP2019;Martindale:The Extra Pharmacopoeia","Marketed","Reverse Transcriptase","Microbiology","Entecavir Hydrate (ETV, Baraclude,BMS200475 Hydrate,SQ34676 Hydrate), a new deoxyguanine nucleoside analogue, is a selective inhibitor of the replication of the hepatitis B virus (HBV).",295.29,"209216-23-9",{"v":59,"d":"59.00"},{"v":199.8,"d":"199.80"},"<1","N/A","https://www.selleckchem.com/products/s1252-entecavir.html","C12H15N5O3.H2O","Hydrate","ETV, Baraclude,BMS200475 Hydrate,SQ34676 Hydrate","O.NC1=NC(=O)C2=C(N1)[N](C=N2)C3CC(O)C(CO)C3=C",-1.611,3,4,2]
["S1255","Nepafenac","g9","L3800-02","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","COX","Neuronal Signaling","Nepafenac (AHR 9434, AL 6515) is a prodrug of amfenac that acts as an inhibitor of COX-1 and COX-2 activity, used in the treatment of pain and inflammation associated with cataract surgery.",254.28,"78281-72-8",{"v":50,"d":"50.00"},196.63,"<1","N/A","http://selleckchem.com/products/Nepafenac.html","C15H14N2O2","free base","AHR 9434, AL 6515","NC(=O)CC1=CC=CC(=C1N)C(=O)C2=CC=CC=C2",1.524,2,2,4]
["S1256","Rufinamide","h9","L3800-02","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","Sodium Channel","Transmembrane Transporters","Rufinamide (CGP 33101,E 2080,RUF 331,Banzel) is a voltage-gated sodium channel blocker, used an anticonvulsant medication.",238.19,"106308-44-5",{"v":18,"d":"18.00"},75.57,"<1","N/A","http://selleckchem.com/products/Rufinamide.html","C10H8F2N4O","free base","CGP 33101,E 2080,RUF 331,Banzel","NC(=O)C1=C[N](CC2=C(F)C=CC=C2F)N=N1",1.437,3,1,3]
["S1257","Posaconazole (SCH 56592)","a10","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","Martindale:The Extra Pharmacopoeia","Marketed","P450 (e.g. CYP17)","Metabolism","Posaconazole (SCH 56592,POS,Noxafil) is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14ɑ demethylase inhibitor with IC50 of 0.25 μM. Posaconazole has a median terminal elimination half-life of 15-35 hours.",700.78,"171228-49-2",{"v":100,"d":"100.00"},{"v":142.7,"d":"142.70"},"<1","N/A","http://selleckchem.com/products/Posaconazole.html","C37H42F2N8O4","free base","SCH 56592,POS,Noxafil","CCC(C(C)O)N1N=CN(C1=O)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(OCC5COC(C5)(C[N]6C=NC=N6)C7=CC=C(F)C=C7F)C=C4",5.096,6,1,12]
["S1258","Prasugrel","b10","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","P2 Receptor","Neuronal Signaling","Prasugrel (Effient, Efient, Prasita,CS-747, LY640315,PCR 4099) is a thienopyridine ADP receptor (P2Y12) antagonist, used for the reduction of thrombotic cardiovascular events.",373.44,"150322-43-3",{"v":30,"d":"30.00"},80.33,"<1","N/A","http://selleckchem.com/products/Prasugrel.html","C20H20FNO3S","Free Base","Effient, Efient, Prasita,CS-747, LY640315,PCR 4099","CC(=O)OC1=CC2=C(CCN(C2)C(C(=O)C3CC3)C4=CC=CC=C4F)S1",3.801,3,0,6]
["S1259","Ramelteon","c10","L3800-02","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","MT Receptor","GPCR & G Protein","Ramelteon (TAK-375) is a novel melatonin receptor agonist for human MT1 and MT2 receptors and chick forebrain melatonin receptors with Ki of 14 pM, 112 pM and 23.1 pM, respectively.",259.34,"196597-26-9",{"v":52,"d":"52.00"},200.51,"<1","N/A","http://selleckchem.com/products/Ramelteon.html","C16H21NO2","free base","TAK-375","CCC(=O)NCCC1CCC2=CC=C3OCCC3=C12",2.826,2,1,4]
["S1260","Cinacalcet (AMG-073) HCl","d10","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP;Martindale:The Extra Pharmacopoeia","Marketed","CaSR","GPCR & G Protein","Cinacalcet (Mimpara, Sensipar,AMG-073) HCl represents a new class of compounds for the treatment of hyperparathyroidism.",393.87,"364782-34-3",{"v":79,"d":"79.00"},200.57,"<1","N/A","http://selleckchem.com/products/Cinacalcet-hydrochloride.html","C22H22F3N.HCl","Hydrochloride","Mimpara, Sensipar,AMG-073","Cl.CC(NCCCC1=CC(=CC=C1)C(F)(F)F)C2=CC=CC3=C2C=CC=C3",6.338,0,1,7]
["S1261","Celecoxib (SC 58635)","e10","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","COX","Neuronal Signaling","Celecoxib (Celebrex, Celebra,SC 58635) is a selective COX-2 inhibitor with IC50 of 40 nM in Sf9 cells.",381.37,"169590-42-5",{"v":76,"d":"76.00"},199.28,"<1","N/A","http://selleckchem.com/products/Celecoxib.html","C17H14F3N3O2S","free base","Celebrex, Celebra,SC 58635","CC1=CC=C(C=C1)C2=CC(=N[N]2C3=CC=C(C=C3)[S](N)(=O)=O)C(F)(F)F",4.428,3,1,4]
["S1262","Avagacestat (BMS-708163)","f10","L3800-02","in 10mM DMSO","N/A","N/A","Phase 2","Beta Amyloid,Notch,Secretase","Proteases","Avagacestat (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.",520.88,"1146699-66-2",{"v":104,"d":"104.00"},199.66,"<1","N/A","http://selleckchem.com/products/BMS-708163.html","C20H17ClF4N4O4S","free base","N/A","NC(=O)C(CCC(F)(F)F)N(CC1=C(F)C=C(C=C1)C2=NOC=N2)[S](=O)(=O)C3=CC=C(Cl)C=C3",3.364,6,1,10]
["S1267","Vemurafenib (PLX4032)","g10","L3800-02","in 10mM DMSO","FDA,EMA,NDC,PMDA","N/A","Marketed","Autophagy,Raf","MAPK","Vemurafenib (PLX4032, RG7204, RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay. 10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold. Vemurafenib (PLX4032, RG7204) induces autophagy.",489.92,"918504-65-1",{"v":97,"d":"97.00"},197.99,"<1","N/A","http://selleckchem.com/products/PLX-4032.html","C23H18ClF2N3O3S","free base","RG7204, RO5185426,PLX4032","CCC[S](=O)(=O)NC1=CC=C(F)C(=C1F)C(=O)C2=C[NH]C3=NC=C(C=C23)C4=CC=C(Cl)C=C4",4.953,4,2,7]
["S1271","Acarbose","h10","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Carbohydrate Metabolism","Metabolism","Acarbose(BAY g 5421,Prandase, Precose, Glucobay, Bay-g 5421) is an inhibitor of intestinal alpha-glucosidase, used to treat type 2 diabetes mellitus.",{"v":645.6,"d":"645.60"},"56180-94-0",{"v":100,"d":"100.00"},154.89,{"v":100,"d":"100.00"},154.89,"http://selleckchem.com/products/Acarbose.html","C25H43NO18","free base","BAY g 5421,Prandase, Precose, Glucobay, Bay-g 5421","CC1OC(OC2C(O)C(O)C(OC2CO)OC3C(O)C(O)C(O)OC3CO)C(O)C(O)C1NC4C=C(CO)C(O)C(O)C4O",-6.839,5,13,9]
["S1276","Adapalene","a11","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Retinoid Receptor","Metabolism","Adapalene (CD-271) is a dual RAR and RXR agonist, used in the treatment of acne.",412.52,"106685-40-9",{"v":8,"d":"8.00"},19.39,"<1","N/A","http://selleckchem.com/products/Adapalene.html","C28H28O3","free base","CD-271","COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(O)=O)[C]45CC6[CH2][CH](C[CH]([CH2]6)C4)C5",6.279,2,0,4]
["S1278","Altretamine","b11","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","DNA alkylator","DNA Damage/DNA Repair","Altretamine (Hexamethylmelamine, NSC13875, ENT50852) is an anti-neoplastic agent.",210.28,"645-05-6",{"v":15,"d":"15.00"},71.33,"<1","N/A","http://selleckchem.com/products/Altretamine.html","C9H18N6","free base","Hexamethylmelamine, NSC13875, ENT50852","CN(C)C1=NC(=NC(=N1)N(C)C)N(C)C",1.995,3,0,3]
["S1280","Amisulpride","c11","L3800-02","in 10mM DMSO","DMF,CFDA,HMA","BP2019;EP9.6;Martindale:The Extra Pharmacopoeia","Preregistration","Dopamine Receptor","Neuronal Signaling","Amisulpride (DAN-2163) is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.",369.48,"71675-85-9",{"v":73,"d":"73.00"},197.57,"<1","N/A","http://selleckchem.com/products/Amisulpride.html","C17H27N3O4S","free base","DAN-2163","CCN1CCCC1CNC(=O)C2=CC(=C(N)C=C2OC)[S](=O)(=O)CC",1.127,4,2,7]
["S1281","Aniracetam","d11","L3800-02","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","Marketed","AMPA Receptor-kainate Receptor-NMDA Receptor","Neuronal Signaling","Aniracetam (RO 13-5057) is a nootropics and neuroprotective drug.",219.24,"72432-10-1",{"v":44,"d":"44.00"},200.69,"<1","N/A","http://selleckchem.com/products/Aniracetam.html","C12H13NO3","free base","RO 13-5057","COC1=CC=C(C=C1)C(=O)N2CCCC2=O",1.267,3,0,2]
["S1282","Artemisinin","e11","L3800-02","in 10mM DMSO","CFDA","Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","N/A","ADC Cytotoxin,Anti-infection","Microbiology","Artemisinin (Qinghaosu,Artemisinine,Coartem,NSC 369397) is a sesquiterpene endoperoxide which is a potent antimalarial agent.",282.33,"63968-64-9",{"v":57,"d":"57.00"},201.89,"<1","N/A","http://selleckchem.com/products/Artemisinin.html","C15H22O5","free base","Qinghaosu,Artemisinine,Coartem,NSC 369397","CC1CCC2C(C)C(=O)OC3OC4(C)CCC1C23OO4",1.998,5,0,0]
["S1283","Asenapine maleate","f11","L3800-02","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","5-HT Receptor,Adrenergic Receptor","Neuronal Signaling","Asenapine maleate (Org 5222) is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder.",401.84,"85650-56-2",{"v":80,"d":"80.00"},199.08,"<1","N/A","http://selleckchem.com/products/Asenapine.html","C17H16ClNO.C4H4O4","Maleate","Org 5222","CN1CC2C(C1)C3=C(OC4=C2C=CC=C4)C=CC(=C3)Cl.OC(=O)\\C=C/C(O)=O",0.883,3,0,2]
["S1284","Benazepril HCl","g11","L3800-02","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","RAAS","Endocrinology & Hormones","Benazepril HCl (CGS 14824A) is a novel angiotensin I converting enzyme inhibitor, used primarily in treatment of hypertension.",460.95,"86541-74-4",{"v":92,"d":"92.00"},199.59,{"v":19,"d":"19.00"},41.22,"http://selleckchem.com/products/Benazepril-hydrochloride.html","C24H28N2O5.HCl","Hydrochloride","CGS 14824A HCl","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC2CCC3=C(C=CC=C3)N(CC(O)=O)C2=O",1.003,4,1,10]
["S1286","Budesonide","h11","L3800-02","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Glucocorticoid Receptor","Endocrinology & Hormones","Budesonide(Labazenit) is a glucocorticoid steroid for the treatment of asthma, non-infectious rhinitis.",430.53,"51333-22-3",{"v":86,"d":"86.00"},199.75,"<1","N/A","http://selleckchem.com/products/Budesonide.html","C25H34O6","free base","Labazenit","CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC3(C)C2(O1)C(=O)CO",2.198,4,2,4]
["S1287","Bumetanide","a2","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010","Phase 3","NKCC","Transmembrane Transporters","Bumetanide (Bumex) is a loop diuretic of the sulfamyl category to treat heart failure. Bumetanide is a selective Na+-K+-Cl- cotransporter 1 (NKCC1) inhibitor, weakly inhibits NKCC2, with IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively.",364.42,"28395-03-1",{"v":73,"d":"73.00"},200.32,"<1","N/A","http://selleckchem.com/products/Bumetanide.html","C17H20N2O5S","free base","N/A","CCCCNC1=C(OC2=CC=CC=C2)C(=CC(=C1)C(O)=O)[S](N)(=O)=O",2.862,4,2,8]
["S1289","Carmofur","b2","L3800-03","in 10mM DMSO","CFDA","KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","N/A","COVID-19,DNA/RNA Synthesis","DNA Damage/DNA Repair","Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.",257.26,"61422-45-5",{"v":52,"d":"52.00"},202.13,"<1","N/A","http://selleckchem.com/products/Carmofur.html","C11H16FN3O3","free base","HCFU","CCCCCCNC(=O)N1C=C(F)C(=O)NC1=O",1.125,3,2,5]
["S1291","Cetirizine DiHCl","c2","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","Histamine Receptor","Neuronal Signaling","Cetirizine DiHCl (Zyrtec, Reactine,UCB P071) is an antihistamine.",461.81,"83881-52-1",{"v":92,"d":"92.00"},199.22,{"v":92,"d":"92.00"},199.22,"http://selleckchem.com/products/Cetirizine-Dihydrochloride.html","C21H25ClN2O3.2HCl","Dihydrochloride","Zyrtec, Reactine,UCB P071","Cl.Cl.OC(=O)COCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3",1.217,2,0,8]
["S1293","Cilnidipine (FRC-8653)","d2","L3800-03","in 10mM DMSO","DMF,CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","Calcium Channel","Transmembrane Transporters","Cilnidipine (FRC-8653) is a unique L-type and N-type calcium channel blocker, used for high blood pressure treatment.",492.52,"132203-70-4",{"v":99,"d":"99.00"},201.01,"<1","N/A","http://selleckchem.com/products/Cilnidipine.html","C27H28N2O7","free base","FRC-8653","COCCOC(=O)C1=C(C)NC(=C(C1C2=CC(=CC=C2)[N+]([O-])=O)C(=O)OC\\C=C\\C3=CC=CC=C3)C",3.686,5,1,12]
["S1294","Cilostazol (OPC-13013)","e2","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","PDE","Metabolism","Cilostazol (Pletal,OPC-13013) is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 μM and inhibitor of adenosine uptake.",369.46,"73963-72-1",{"v":74,"d":"74.00"},200.29,"<1","N/A","http://selleckchem.com/products/Cilostazol.html","C20H27N5O2","free base","Pletal,OPC-13013","O=C1CCC2=C(N1)C=CC(=C2)OCCCCC3=NN=N[N]3C4CCCCC4",{"v":3.23,"d":"3.230"},5,1,7]
["S1299","Floxuridine (NSC 27640)","f2","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","Phase 2","Apoptosis related,CMV,DNA/RNA Synthesis","DNA Damage/DNA Repair","Floxuridine (NSC 27640, Deoxyfluorouridine, FUDR) is a prodrug that is rapidly catabolized to 5-fluorouracil in vivo. Floxuridine is used to treat various cancers, particularly metastases to the liver. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage and apoptosis. Floxuridine has antiviral effects against HSV and CMV.",246.19,"50-91-9",{"v":49,"d":"49.00"},199.03,{"v":49,"d":"49.00"},199.03,"http://selleckchem.com/products/Floxuridine.html","C9H11FN2O5","free base","Deoxyfluorouridine, FUDR,NSC 27640","OCC1OC(CC1O)N2C=C(F)C(=O)NC2=O",-1.775,3,3,2]
["S1300","Tegafur (FT-207)","g2","L3800-03","in 10mM DMSO","DMF,EMA,HMA,CFDA,PMDA","KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","DNA/RNA Synthesis","DNA Damage/DNA Repair","Tegafur (NSC 148958,Fluorafur,FT-207) is a substance being used in the treatment of some types of cancer.",200.17,"17902-23-7",{"v":40,"d":"40.00"},199.83,{"v":8,"d":"8.00"},39.97,"http://selleckchem.com/products/Ftorafur.html","C8H9FN2O3","free base","NSC 148958,Fluorafur,FT-207","FC1=CN(C2CCCO2)C(=O)NC1=O",-0.625,3,1,1]
["S1302","Ifosfamide (NSC109724)","h2","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","DNA alkylator,DNA/RNA Synthesis","DNA Damage/DNA Repair","Ifosfamide (Mitoxana, Ifex,Isophosphamide,NSC109724) is a nitrogen mustard alkylating agent used in the treatment of cancer.",261.09,"3778-73-2",{"v":52,"d":"52.00"},199.17,{"v":52,"d":"52.00"},199.17,"http://selleckchem.com/products/Ifosfamide.html","C7H15Cl2N2O2P","free base","Mitoxana, Ifex,Isophosphamide,NSC109724","ClCCN[P]1(=O)OCCCN1CCCl",0.144,2,1,5]
["S1304","Megestrol Acetate","a3","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Androgen Receptor,Estrogen/progestogen Receptor","Endocrinology & Hormones","Megestrol acetate (BDH1298, SC10363) is a synthetic progestogen, used to treat breast cancer and loss of appetite.",384.51,"595-33-5",{"v":33,"d":"33.00"},85.82,"<1","N/A","http://selleckchem.com/products/Megestrol-Acetate.html","C24H32O4","free base","BDH1298, SC10363","CC(=O)OC1(CCC2C3C=C(C)C4=CC(=O)CCC4(C)C3CCC12C)C(C)=O",3.505,4,0,3]
["S1305","Mercaptopurine (6-MP)","b3","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","DNA/RNA Synthesis","DNA Damage/DNA Repair","Mercaptopurine(6-MP) is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.",152.18,"50-44-2",{"v":30,"d":"30.00"},197.13,"<1","N/A","http://selleckchem.com/products/Mercaptopurine.html","C5H4N4S","free base","6-MP","S=C1N=CNC2=C1[NH]C=N2",0.367,2,2,0]
["S1319","Costunolide","c3","L3800-03","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Telomerase","DNA Damage/DNA Repair","Costunolide (NSC 106404), a natural sesquiterpene compound with multiple biological activities; inhibits FPTase with IC50 of 20 μM, also inhibits telomerase with IC50 of 65-90 μM.",232.32,"553-21-9",{"v":47,"d":"47.00"},202.31,"<1","N/A","http://selleckchem.com/products/Costunolide.html","C15H20O2","free base","NSC 106404","CC/1=C\\CC\\C(=C\\C2OC(=O)C(=C)C2CC1)C",4.022,2,0,0]
["S1322","Dexamethasone (MK-125)","d3","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP39-NF34;BP2015;JP16;IP2010","Phase 3","Autophagy,Complement System,COVID-19,Glucocorticoid Receptor,IL Receptor,Mitophagy","Immunology & Inflammation","Dexamethasone (MK-125, NSC 34521, Hexadecadrol, Prednisolone F) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects. Dexamethasone induces autophagy and mitophagy. Dexamethasone is tested in hospitalized patients with COVID-19 and is found to have benefits for critically ill patients.",392.46,"50-02-2",{"v":79,"d":"79.00"},201.29,"<1","N/A","http://selleckchem.com/products/Dexamethasone.html","C22H29FO5","free base","NSC 34521, Hexadecadrol, Prednisolone F,MK-125","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO",1.708,2,2,2]
["S1324","Doxazosin Mesylate","e3","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.8;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Doxazosin, a quinazoline-derivative, selectively antagonizes postsynaptic α1-adrenergic receptors, used in the treatment of high blood pressure and urinary retention associated with benign prostatic hyperplasia.",547.58,"77883-43-3",{"v":15,"d":"15.00"},27.39,"<1","N/A","http://selleckchem.com/products/Doxazosin-mesylate.html","C23H25N5O5.CH4O3S","Mesylate","N/A","COC1=C(OC)C=C2C(=NC(=NC2=C1)N3CCN(CC3)C(=O)C4COC5=C(O4)C=CC=C5)N.C[S](O)(=O)=O",2.071,7,1,4]
["S1326","Edaravone","f3","L3800-03","in 10mM DMSO","FDA,CFDA,NDC,PMDA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","Antioxidant","ER stress & UPR","Edaravone (MCI-186) is a novel potent free radical scavenger that has been clinically used to reduce the neuronal damage following ischemic stroke.",{"v":174.2,"d":"174.20"},"89-25-8",{"v":35,"d":"35.00"},200.92,"<1","N/A","http://selleckchem.com/products/Edaravone.html","C10H10N2O","free base","MCI-186","CC1=NN(C(=O)C1)C2=CC=CC=C2",1.123,2,0,1]
["S1328","Etodolac","g3","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","COX","Neuronal Signaling","Etodolac(AY-24236) is a nonsteroidal anti-inflammatory drug (NSAID) and a COX inhibitor, used for the treatment of inflammation and pain.",287.35,"41340-25-4",{"v":58,"d":"58.00"},201.84,"<1","N/A","http://selleckchem.com/products/Etodolac.html","C17H21NO3","free base","AY-24236","CCC1=CC=CC2=C1[NH]C3=C2CCOC3(CC)CC(O)=O",3.723,2,1,4]
["S1330","Felbamate","h3","L3800-03","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","NMDAR","Neuronal Signaling","Felbamate (Felbatol, ADD-03055,W-554) is an anticonvulsant drug used in the treatment of epilepsy; NMDAR antagonist.",238.24,"25451-15-4",{"v":48,"d":"48.00"},201.48,"<1","N/A","http://selleckchem.com/products/Felbamate.html","C11H14N2O4","free base","Felbatol, ADD-03055,W-554","NC(=O)OCC(COC(N)=O)C1=CC=CC=C1",0.984,4,2,7]
["S1331","Fluconazole (UK 49858)","a4","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Fungal,P450 (e.g. CYP17)","Metabolism","Fluconazole (Diflucan, Trican, Alfumet,UK 49858) is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol,used in the treatment and prevention of superficial and systemic fungal infections.",306.27,"86386-73-4",{"v":61,"d":"61.00"},199.17,"<1","N/A","http://selleckchem.com/products/Fluconazole.html","C13H12F2N6O","free base","Diflucan, Trican, Alfumet,UK 49858","OC(C[N]1C=NC=N1)(C[N]2C=NC=N2)C3=C(F)C=C(F)C=C3",{"v":0.75,"d":"0.750"},4,0,5]
["S1332","Flumazenil (RO 15-1788)","b4","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Phase 2/3","GABA Receptor","Neuronal Signaling","Flumazenil (RO 15-1788) is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses.",303.29,"78755-81-4",{"v":5,"d":"5.00"},16.49,"<1","N/A","http://selleckchem.com/products/Flumazenil.html","C15H14FN3O3","free base","RO 15-1788","CCOC(=O)C1=C2CN(C)C(=O)C3=CC(=CC=C3[N]2C=N1)F",1.583,4,0,3]
["S1333","Fluoxetine (Lilly 110140) HCl","c4","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor","Neuronal Signaling","Fluoxetine HCl (Prozac, Sarafem,LY-110140) is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, used in the treatment of depression.",345.79,"56296-78-7",{"v":69,"d":"69.00"},199.54,{"v":4,"d":"4.00"},11.57,"http://selleckchem.com/products/Fluoxetine-hydrochloride.html","C17H18F3NO.HCl","Hydrochloride","Prozac, Sarafem,LY-110140","Cl.CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C2=CC=CC=C2",4.415,1,1,7]
["S1334","Flupirtine maleate","d4","L3800-03","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia","N/A","DNA/RNA Synthesis","DNA Damage/DNA Repair","Flupirtine maleate is the salt form of Flupirtine, which is a centrally acting non-opioid analgesia, is a selective neuronal potassium channel opener that also has NMDA receptor antagonist properties.",420.39,"75507-68-5",{"v":84,"d":"84.00"},199.81,"<1","N/A","http://selleckchem.com/products/Flupirtine-maleate.html","C15H17FN4O2.C4H4O4","Maleate","N/A","CCOC(=O)NC1=C(N)N=C(NCC2=CC=C(F)C=C2)C=C1.OC(=O)\\C=C\\C(O)=O",{"v":2.76,"d":"2.760"},5,3,8]
["S1336","Fluvoxamine (DU-23000) maleate","e4","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Serotonin Transporter","Neuronal Signaling","Fluvoxamine maleate (DU-23000, MK-264) is a selective serotonin (5-HT) reuptake inhibitor (SSRI), used in the treatment of obsessive-compulsive disorder.",434.41,"61718-82-9",{"v":87,"d":"87.00"},200.27,"<1","N/A","http://selleckchem.com/products/Fluvoxamine-maleate.html","C19H25F3N2O6","Maleate","MK-264,DU-23000 maleate","COCCCCC(=N\\OCCN)/C1=CC=C(C=C1)C(F)(F)F.OC(=O)\\C=C/C(O)=O",0.111,5,1,12]
["S1340","Gatifloxacin","f4","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Topoisomerase","DNA Damage/DNA Repair","Gatifloxacin (AM-1155, CG5501, BMS-206584) is an antibiotic of the fourth-generation fluoroquinolone family, and inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.",375.39,"112811-59-3",{"v":7,"d":"7.00"},18.65,"<1","N/A","http://selleckchem.com/products/Gatifloxacin.html","C19H22FN3O4","free base","AM-1155, CG5501, BMS-206584","COC1=C2N(C=C(C(O)=O)C(=O)C2=CC(=C1N3CCNC(C)C3)F)C4CC4",-0.909,3,1,4]
["S1342","Genistein (NPI 031L)","g4","L3800-03","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia","Phase 1/2","EGFR,Topoisomerase","Protein Tyrosine Kinase","Genistein (NPI 031L), a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK)  which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM.",270.24,"446-72-0",{"v":54,"d":"54.00"},199.82,"<1","N/A","http://selleckchem.com/products/Genistein.html","C15H10O5","free base","NPI 031L","OC1=CC=C(C=C1)C2=COC3=C(C(=CC(=C3)O)O)C2=O",{"v":2.14,"d":"2.140"},2,3,1]
["S1344","Glimepiride","h4","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Potassium Channel","Transmembrane Transporters","Glimepiride(HOE-490) is a potent Kir6.2/SUR inhibitor with IC50 of 3.0 nM, 5.4 nM, and 7.3 nM for SUR1, SUR2A and SUR2B, used in the treatment of type 2 diabetes mellitus.",490.62,"93479-97-1",{"v":11,"d":"11.00"},22.42,"<1","N/A","http://selleckchem.com/products/Glimepiride.html","C24H34N4O5S","free base","HOE-490","CCC1=C(C)CN(C(=O)NCCC2=CC=C(C=C2)[S](=O)(=O)NC(=O)NC3CCC(C)CC3)C1=O",3.781,5,3,7]
["S1351","Ivermectin (MK-933)","a5","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","AChR,Autophagy,Chloride Channel,COVID-19,HIV,Mitophagy,P2 Receptor","Transmembrane Transporters","Ivermectin (MK-933, IVM) is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug. Ivermectin (MK-933, IVM) is a specific positive allosteric effector of P2X4 and α7 nicotinic acetylcholine receptors (nAChRs). Ivermectin has potent antiviral activity towards both HIV-1 and dengue virus. Ivermectin induces autophagy through the AKT/mTOR signaling pathway and mitophagy.",875.09,"70288-86-7",{"v":100,"d":"100.00"},114.27,"<1","N/A","http://selleckchem.com/products/Ivermectin.html","C48H74O14","Free Base","MK-933","CCC(C)C1OC2(CCC1C)CC3CC(C\\C=C(C)\\C(OC4CC(OC)C(OC5CC(OC)C(O)C(C)O5)C(C)O4)C(C)\\C=C\\C=C\\6COC7C(O)C(=CC(C(=O)O3)C67O)C)O2",4.743,11,2,8]
["S1352","TG100-115","b5","L3800-03","in 10mM DMSO","N/A","N/A","Phase 2","PI3K","PI3K/Akt/mTOR","TG100-115 is a PI3Kγ/δ inhibitor with IC50 of 83 nM/235 nM, with little effect on PI3Kα/β. Phase 1/2.",346.34,"677297-51-7",{"v":9,"d":"9.00"},25.99,"<1","N/A","http://selleckchem.com/products/TG100-115.html","C18H14N6O2","free base","N/A","NC1=NC2=NC(=C(N=C2C(=N1)N)C3=CC(=CC=C3)O)C4=CC=CC(=C4)O",2.687,4,4,2]
["S1354","Lansoprazole","c5","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.3;BP2019;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","ATPase,Proton Pump","Transmembrane Transporters","Lansoprazole (A-65006, AG-1749) is a proton-pump inhibitor (PPI) that binds covalently to parietal cell H(+),K(+)-ATPase. Lansoprazole prevents the stomach from producing gastric acid.",369.36,"103577-45-3",{"v":74,"d":"74.00"},200.35,"<1","N/A","http://selleckchem.com/products/Lansoprazole.html","C16H14F3N3O2S","free base","A-65006, AG-1749","CC1=C(OCC(F)(F)F)C=CN=C1C[S](=O)C2=NC3=CC=CC=C3[NH]2",3.442,4,1,6]
["S1356","Levetiracetam (UCB-L059)","d5","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.4;BP2019;Martindale:The Extra Pharmacopoeia","Marketed","AChR,Calcium Channel","Transmembrane Transporters","Levetiracetam (UCB-L059, SIB-S1) is an anticonvulsant medication used to treat epilepsy. Levetiracetam (UCB-L059, SIB-S1) is an agonist of muscarinic acetylcholine receptors (mAChR). Levetiracetam modulates the presynaptic P/Q-type voltage-dependent calcium (Ca2+) channel.",170.21,"102767-28-2",{"v":34,"d":"34.00"},199.75,{"v":34,"d":"34.00"},199.75,"http://selleckchem.com/products/Levetiracetam.html","C8H14N2O2","free base","UCB-L059, SIB-S1","CCC(N1CCCC1=O)C(N)=O",-0.304,2,1,3]
["S1357","Lidocaine","e5","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Ph.Int_6th;JP17;BP2017;USP40-NF35;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Histamine Receptor","Neuronal Signaling","Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.",234.34,"137-58-6",{"v":47,"d":"47.00"},200.56,{"v":9,"d":"9.00"},38.41,"http://selleckchem.com/products/Lidocaine.html","C14H22N2O","Free Base","Alphacaine","CCN(CC)CC(=O)NC1=C(C)C=CC=C1C",2.626,1,1,5]
["S1358","Loratadine (SCH29851)","f5","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Histamine Receptor","Neuronal Signaling","Loratadine (Alavert,Claritin,SCH29851) is a histamine H1 receptor antagonist, used to treat allergies. Also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.",382.88,"79794-75-5",{"v":17,"d":"17.00"},{"v":44.4,"d":"44.40"},"<1","N/A","http://selleckchem.com/products/Loratadine.html","C22H23ClN2O2","free base","Alavert,Claritin,SCH29851","CCOC(=O)N1CCC(CC1)=C2C3=C(CCC4=C2N=CC=C4)C=C(Cl)C=C3",{"v":5,"d":"5.000"},3,0,2]
["S1359","Losartan Potassium (DuP 753)","g5","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Angiotensin Receptor","GPCR & G Protein","Losartan Potassium (DuP 753, MK 954) is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.",462.01,"124750-99-8",{"v":92,"d":"92.00"},199.13,{"v":92,"d":"92.00"},199.13,"http://selleckchem.com/products/losartan-potassium.html","C22H23ClKN6O","Potassium salt","MK 954,DuP 753","[KH].CCCCC1=NC(=C(CO)[N]1CC2=CC=C(C=C2)C3=C(C=CC=C3)C4=NN=N[NH]4)Cl",4.241,4,2,8]
["S1361","MGCD-265 analog","h5","L3800-03","in 10mM DMSO","N/A","N/A","Phase 2","c-Met,RON,Tie-2,VEGFR","Protein Tyrosine Kinase","MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively; also inhibits Ron and Tie2. Phase 1/2.",{"v":517.6,"d":"517.60"},"875337-44-3",{"v":104,"d":"104.00"},200.93,"<1","N/A","https://www.selleckchem.com/products/mgcd-265-analog.html","C26H20FN5O2S2","free base","N/A","C[N]1C=NC(=C1)C2=CC3=NC=CC(=C3S2)OC4=CC=C(NC(=S)NC(=O)CC5=CC=CC=C5)C=C4F",6.037,4,2,8]
["S1362","Rigosertib (ON-01910)","a6","L3800-03","in 10mM DMSO","N/A","N/A","Phase 3","Akt,Apoptosis related,PI3K,PLK","Cell Cycle","Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM in a cell-free assay. It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals. Rigosertib induces apoptosis in various cancer cells. Phase 3.",473.47,"1225497-78-8",{"v":95,"d":"95.00"},200.65,{"v":95,"d":"95.00"},200.65,"http://selleckchem.com/products/ON-01910.html","C21H24NNaO8S","Sodium Salt","N/A","[Na+].COC1=CC(=C(\\C=C\\[S](=O)(=O)CC2=CC=C(OC)C(=C2)NCC([O-])=O)C(=C1)OC)OC",0.632,6,1,11]
["S1364","Patupilone (Epothilone B)","b6","L3800-03","in 10mM DMSO","N/A","N/A","Phase 3","Microtubule Associated","Cytoskeletal Signaling","Patupilone (EPO906, Epothilone B) is a paclitaxel-like microtubule-stabilizing agent with EC0.01 of 1.8 μM. Phase 2.",507.68,"152044-54-7",{"v":102,"d":"102.00"},200.91,"<1","N/A","http://selleckchem.com/products/Epothilone-B.html","C27H41NO6S","free base","EPO906","CC1CCCC2(C)OC2CC(OC(=O)CC(O)C(C)(C)C(=O)C(C)C1O)\\C(C)=C\\C3=CSC(=N3)C",3.779,5,2,2]
["S1366","BMS-707035","c6","L3800-03","in 10mM DMSO","N/A","N/A","Phase 2","Integrase","Microbiology","BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.",410.42,"729607-74-3",{"v":38,"d":"38.00"},92.59,"<1","N/A","http://selleckchem.com/products/BMS-707035.html","C17H19FN4O5S","free base","N/A","CN1C(=O)C(=C(N=C1N2CCCC[S]2(=O)=O)C(=O)NCC3=CC=C(F)C=C3)O",0.385,5,2,4]
["S1367","Amonafide","d6","L3800-03","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia","N/A","Topoisomerase","DNA Damage/DNA Repair","Amonafide (NSC308847, AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage. Phase 3.",283.33,"69408-81-7",{"v":57,"d":"57.00"},201.18,"<1","N/A","http://selleckchem.com/products/Amonafide.html","C16H17N3O2","free base","NSC308847,AS1413","CN(C)CCN1C(=O)C2=C3C(=CC=C2)C=C(N)C=C3C1=O",1.162,2,1,3]
["S1368","Acitretin","e6","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.5;Martindale:The Extra Pharmacopoeia","Marketed","Retinoid Receptor","Metabolism","Acitretin (Etretin, RO 10-1670) is a second generation retinoid used for psoriasis.",326.43,"55079-83-9",{"v":20,"d":"20.00"},61.27,"<1","N/A","http://selleckchem.com/products/Acitretin.html","C21H26O3","free base","Etretin, RO 10-1670","COC1=CC(=C(\\C=C\\C(C)=C\\C=C\\C(C)=C\\C(O)=O)C(=C1C)C)C",5.665,2,0,6]
["S1369","Bafetinib (INNO-406)","f6","L3800-03","in 10mM DMSO","N/A","N/A","Phase 2","Bcr-Abl","Angiogenesis","Bafetinib (INNO-406, NS-187) is a potent and selective dual Bcr-Abl/Lyn inhibitor with IC50 of 5.8 nM/19 nM in cell-free assays, does not inhibit the phosphorylation of the T315I mutant and is less potent to PDGFR and c-Kit.",576.62,"859212-16-1",{"v":100,"d":"100.00"},173.42,"<1","N/A","http://selleckchem.com/products/Bafetinib.html","C30H31F3N8O","free base","NS-187","CN(C)C1CCN(C1)CC2=CC=C(C=C2C(F)(F)F)C(=O)NC3=CC=C(C)C(=C3)NC4=NC=CC(=N4)C5=CN=CN=C5",4.197,5,2,9]
["S1373","Daptomycin (LY146032)","g6","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics,Antibiotics for Mammalian Cell Culture,Bacterial,DNA/RNA Synthesis","DNA Damage/DNA Repair","Daptomycin (Cubicin,LY146032) is a novel antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.",1620.67,"103060-53-3",{"v":100,"d":"100.00"},{"v":61.7,"d":"61.70"},{"v":100,"d":"100.00"},{"v":61.7,"d":"61.70"},"http://selleckchem.com/products/Daptomycin.html","C72H101N17O26","free base","Cubicin,LY146032","CCCCCCCCCC(=O)NC(CC1=C[NH]C2=C1C=CC=C2)C(=O)NC(CC(N)=O)C(=O)NC(CC(O)=O)C(=O)NC3C(C)OC(=O)C(CC(=O)C4=CC=CC=C4N)NC(=O)C(NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CCCN)NC(=O)CNC3=O)C(C)CC(O)=O",-7.895,21,18,35]
["S1374","Doripenem Hydrate","h6","L3800-03","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics","Microbiology","Doripenem Hydrate (S-4661) is an ultra-broad-spectrum injectable antibiotic, used to treat complicated intra-abdominal infections and complicated urinary tract infections.",438.52,"364622-82-2",{"v":36,"d":"36.00"},82.09,{"v":26,"d":"26.00"},59.29,"http://selleckchem.com/products/Doripenem-Hydrate.html","C15H24N4O6S2.H2O","Hydrate","S-4661","O.CC(O)C1C2C(C)C(=C(N2C1=O)C(O)=O)SC3CNC(CN[S](N)(=O)=O)C3",-5.546,4,4,7]
["S1376","Gestodene","a7","L3800-03","in 10mM DMSO","DMF,CFDA,NDC,HMA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Gestodene (SH B 331,WL 70) is a progestogen hormonal contraceptive.",310.43,"60282-87-3",{"v":62,"d":"62.00"},199.72,"<1","N/A","http://selleckchem.com/products/Gestodene.html","C21H26O2","free base","SH B 331,WL 70","CCC12CCC3C(CCC4=CC(=O)CCC34)C1C=CC2(O)C#C",4.462,1,0,1]
["S1377","Drospirenone","b7","L3800-03","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Preregistration","Estrogen/progestogen Receptor","Endocrinology & Hormones","Drospirenone (ZK 3059) is a synthetic progestin that is an analog to spironolactone.",366.49,"67392-87-4",{"v":73,"d":"73.00"},199.19,"<1","N/A","http://selleckchem.com/products/Drospirenone.html","C24H30O3","free base","ZK 3059","CC12CCC(=O)C=C1C3CC3C4C2CCC5(C)C4C6CC6C57CCC(=O)O7",3.383,3,0,0]
["S1378","Ruxolitinib (INCB018424)","c7","L3800-03","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Apoptosis related,Autophagy,JAK,Mitophagy","JAK/STAT","Ruxolitinib (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis.",306.37,"941678-49-5",{"v":61,"d":"61.00"},199.11,"<1","N/A","http://selleckchem.com/products/INCB18424.html","C17H18N6","free base","INCB018424","N#CCC(C1CCCC1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4",{"v":2.88,"d":"2.880"},3,1,4]
["S1379","Isotretinoin","d7","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.5;Martindale:The Extra Pharmacopoeia","Marketed","Hydroxylase","Metabolism","Isotretinoin (13-cis retinoic acid) was developed to be used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more.",300.44,"4759-48-2",{"v":60,"d":"60.00"},199.71,"<1","N/A","http://selleckchem.com/products/Isotretinoin.html","C20H28O2","free base","13-cis retinoic acid","CC1=C(\\C=C\\C(C)=C\\C=C\\C(C)=C/C(O)=O)C(C)(C)CCC1",5.551,1,0,5]
["S1380","Lopinavir (ABT-378)","e7","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","COVID-19,HIV Protease","Proteases","Lopinavir (ABT-378) is a potent HIV protease inhibitor with Ki of 1.3 pM in a cell-free assay.",{"v":628.8,"d":"628.80"},"192725-17-0",{"v":126,"d":"126.00"},200.38,"<1","N/A","http://selleckchem.com/products/Lopinavir.html","C37H48N4O5","free base","ABT-378","CC(C)C(N1CCCNC1=O)C(=O)NC(CC(O)C(CC2=CC=CC=C2)NC(=O)COC3=C(C)C=CC=C3C)CC4=CC=CC=C4",4.926,4,4,15]
["S1381","Meropenem","f7","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics","Microbiology","Meropenem (SM 7338) is an ultra-broad spectrum injectable antibiotic.",383.46,"96036-03-2",{"v":76,"d":"76.00"},{"v":198.2,"d":"198.20"},{"v":8,"d":"8.00"},20.86,"http://selleckchem.com/products/Meropenem.html","C17H25N3O5S","free base","SM 7338","CC(O)C1C2C(C)C(=C(N2C1=O)C(O)=O)SC3CNC(C3)C(=O)N(C)C",-4.129,3,2,5]
["S1382","Mianserin HCl","g7","L3800-03","in 10mM DMSO","DMF,CFDA,PMDA","BP2019;EP9.2;IP2010","Phase 4","Histamine Receptor","Neuronal Signaling","Mianserin (Bolvidon, Norval, Tolvon,ORG GB-94 HCl,Mianserin hydrochloride) is an potent antagonist of H1 histamine receptor and 5-HT serotonin receptors, used for the treatment of depression.",300.83,"21535-47-7",{"v":60,"d":"60.00"},199.45,{"v":30,"d":"30.00"},99.72,"http://selleckchem.com/products/mianserin-hydrochloride.html","C18H20N2.HCl","Hydrochloride","Bolvidon, Norval, Tolvon,ORG GB-94 HCl,Mianserin hydrochloride","Cl.CN1CCN2C(C1)C3=C(CC4=C2C=CC=C4)C=CC=C3",4.088,0,0,0]
["S1385","Mosapride Citrate","h7","L3800-03","in 10mM DMSO","DMF,CFDA,PMDA","KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor","Neuronal Signaling","Mosapride Citrate (TAK-370, AS-4370, Gasmotin) is a gastroprokinetic agent that acts as a selective 5HT4 agonist.",614.02,"112885-42-4",{"v":90,"d":"90.00"},146.58,"<1","N/A","http://selleckchem.com/products/Mosapride-citrate.html","C21H25ClFN3O3.C6H8O7","Citrate","TAK-370, AS-4370, Gasmotin","CCOC1=CC(=C(Cl)C=C1C(=O)NCC2CN(CCO2)CC3=CC=C(F)C=C3)N.OC(=O)CC(O)(CC(O)=O)C(O)=O",-1.422,6,2,12]
["S1386","Nafamostat mesilate (FUT-175)","a8","L3800-03","in 10mM DMSO","PMDA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,COVID-19,SARS-CoV,Serine Protease","Proteases","Nafamostat mesilate (Futhan, FUT-175) is a synthetic serine protease inhibitor, used as an anticoagulant during hemodialysis. Nafamostat mesylate blocks activation of SARS-CoV-2 and is investigated as a new treatment option for COVID-19. Nafamostat Mesilate attenuates inflammation and apoptosis.",539.58,"82956-11-4",{"v":20,"d":"20.00"},37.07,{"v":53,"d":"53.00"},98.22,"http://selleckchem.com/products/Nafamostat-mesylate.html","C19H17N5O2.2CH4O3S","Dimesylate","Futhan, FUT-175","C[S](O)(=O)=O.C[S](O)(=O)=O.NC(=N)NC1=CC=C(C=C1)C(=O)OC2=CC3=C(C=C2)C=C(C=C3)C(N)=N",1.364,2,3,6]
["S1387","Naftopidil DiHCl","b8","L3800-03","in 10mM DMSO","DMF,CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Naftopidil DiHCl (Flivas, KT-611, Avishot,BM-15275) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.",465.41,"57149-08-3",{"v":41,"d":"41.00"},88.09,"<1","N/A","http://selleckchem.com/products/Naftopidil-Dihydrochloride.html","C24H28N2O3.2HCl","Dihydrochloride","Flivas, KT-611, Avishot,BM-15275","Cl.Cl.COC1=CC=CC=C1N2CCN(CC2)CC(O)COC3=C4C=CC=CC4=CC=C3",4.726,2,1,7]
["S1389","Omeprazole","c8","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.7;BP2019;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","ATPase,Autophagy,Proton Pump","Transmembrane Transporters","Omeprazole is a proton pump inhibitor that blocks H(+)-K(+)-ATPase, used to treat dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, laryngopharyngeal reflux, and Zollinger–Ellison syndrome.",345.42,"73590-58-6",{"v":69,"d":"69.00"},199.76,"<1","N/A","http://selleckchem.com/products/Omeprazole.html","C17H19N3O3S","free base","N/A","COC1=CC=C2[NH]C(=NC2=C1)[S](=O)CC3=C(C)C(=C(C)C=N3)OC",2.904,5,1,5]
["S1390","Ondansetron HCl","d8","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor","Neuronal Signaling","Ondansetron HCl (Ondemet, Emeset, Emetron,GR 38032F,SN 307) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation therapy.",329.82,"99614-01-4",{"v":66,"d":"66.00"},200.11,{"v":24,"d":"24.00"},72.77,"http://selleckchem.com/products/Ondansetron-hydrochloride.html","C18H19N3O.HCl","Hydrochloride","Ondemet, Emeset, Emetron,GR 38032F,SN 307","Cl.C[N]1C2=C(C(=O)C(CC2)C[N]3C=CN=C3C)C4=CC=CC=C14",3.016,2,0,2]
["S1391","Oxcarbazepine","e8","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Sodium Channel","Transmembrane Transporters","Oxcarbazepine (GP47680) inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM.",252.27,"28721-07-5",{"v":7,"d":"7.00"},27.75,"<1","N/A","http://selleckchem.com/products/Oxcarbazepine.html","C15H12N2O2","free base","GP47680","NC(=O)N1C2=C(CC(=O)C3=C1C=CC=C3)C=CC=C2",2.131,2,1,0]
["S1392","Pelitinib (EKB-569)","f8","L3800-03","in 10mM DMSO","N/A","N/A","Phase 2","EGFR,MEK,Src","Protein Tyrosine Kinase","Pelitinib (EKB-569) is a potent irreversible EGFR inhibitor with IC50 of 38.5 nM. Pelitinib (EKB-569) also slightly inhibits Src, MEK/ERK and ErbB2 with IC50s of 282 nM, 800 nM and 1255 nM, respectively. Phase2.",467.92,"257933-82-7",{"v":13,"d":"13.00"},27.78,"<1","N/A","http://selleckchem.com/products/Pelitinib.html","C24H23ClFN5O2","free base","N/A","CCOC1=C(NC(=O)\\C=C\\CN(C)C)C=C2C(=C1)N=CC(=C2NC3=CC(=C(F)C=C3)Cl)C#N",4.455,3,2,8]
["S1393","Pirarubicin (NSC-333054)","g8","L3800-03","in 10mM DMSO","DMF,CFDA","KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Antineoplastic and Immunosuppressive Antibiotics,Topoisomerase","DNA Damage/DNA Repair","Pirarubicin (NSC-333054,THP) is an anthracycline antibiotic, and also a DNA/RNA synthesis inhibitor by intercalating into DNA and interacts with topoisomerase II, used as an antineoplastic agent.",627.64,"72496-41-4",{"v":7,"d":"7.00"},11.15,"<1","N/A","http://selleckchem.com/products/Pirarubicin.html","C32H37NO12","free base","NSC-333054,THP","COC1=CC=CC2=C1C(=O)C3=C(O)C4=C(CC(O)(CC4OC5CC(N)C(OC6CCCCO6)C(C)O5)C(=O)CO)C(=C3C2=O)O",1.091,8,4,7]
["S1394","Pizotifen Malate","h8","L3800-03","in 10mM DMSO","CFDA","BP2019;Martindale:The Extra Pharmacopoeia","N/A","5-HT Receptor","Neuronal Signaling","Pizotifen Malate (Sandomigran, pizotyline,BC-105) is a benzocycloheptane based agent used for recurrent migraine headaches.",429.53,"5189-11-7",{"v":21,"d":"21.00"},48.89,"<1","N/A","http://selleckchem.com/products/Pizotifen-malate.html","C19H21NS.C4H6O5","Malate","Sandomigran, pizotyline,BC-105","CN1CCC(CC1)=C2C3=C(CCC4=C2C=CC=C4)SC=C3.OC(CC(O)=O)C(O)=O",0.292,2,1,3]
["S1396","Resveratrol (SRT501)","a9","L3800-03","in 10mM DMSO","DMF,NDC","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","AMPK,Apoptosis related,Autophagy,COX,ERK,IκB/IKK,JNK,Lipoxygenase,Mitophagy,Sirtuin,Src,STAT","Autophagy","Resveratrol (SRT501, trans-Resveratrol) has a wide spectrum of targets including cyclooxygenases(i.e. COX, IC50=1.1 μM), lipooxygenases（LOX, IC50=2.7 μM）, kinases, sirtuins and other proteins. It has anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects. Resveratrol induces mitophagy/autophagy and autophagy-dependent apoptosis.",228.24,"501-36-0",{"v":45,"d":"45.00"},197.16,"<1","N/A","http://selleckchem.com/products/Resveratrol.html","C14H12O3","free base","trans-Resveratrol,SRT501","OC1=CC=C(C=C1)\\C=C\\C2=CC(=CC(=C2)O)O",{"v":3.09,"d":"3.090"},0,3,2]
["S1397","Rocuronium Bromide","b9","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","AChR","Neuronal Signaling","Rocuronium Bromide (ORG 9426) is a competitive AchR antagonist, used in modern anaesthesia.",609.68,"119302-91-9",{"v":122,"d":"122.00"},{"v":200.1,"d":"200.10"},{"v":122,"d":"122.00"},{"v":200.1,"d":"200.10"},"http://selleckchem.com/products/Rocuronium-bromide.html","C32H53N2O4.Br","Bromide","ORG 9426","[Br-].CC(=O)OC1C(CC2C3CCC4CC(O)C(CC4(C)C3CCC12C)N5CCOCC5)[N+]6(CCCC6)CC=C",0.282,3,1,6]
["S1398","Stavudine (d4T)","c9","L3800-03","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;IP2010","Marketed","Reverse Transcriptase","Microbiology","Stavudine (d4T, BMY-27857, Sanilvudine, NSC 163661) is a nucleoside analog reverse transcriptase inhibitor (NARTI) active against HIV.",224.21,"3056-17-5",{"v":45,"d":"45.00"},{"v":200.7,"d":"200.70"},"<1","N/A","http://selleckchem.com/products/Stavudine.html","C10H12N2O4","free base","BMY-27857, Sanilvudine, NSC 163661,d4T","CC1=CN(C2OC(CO)C=C2)C(=O)NC1=O",-0.515,3,2,2]
["S1400","Tenofovir (GS 1278) Disoproxil Fumarate","d9","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","HIV,Reverse Transcriptase","Microbiology","Tenofovir Disoproxil Fumarate (Tenofovir DF,GS-1278 Disoproxil Fumarate) belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination.",635.51,"202138-50-9",{"v":100,"d":"100.00"},157.35,"<1","N/A","http://selleckchem.com/products/Tenofovir-Disoproxil-Fumarate.html","C19H30N5O10P.C4H4O4","Fumarate","Tenofovir DF,GS-1278 Disoproxil Fumarate","CC(C)OC(=O)OCO[P](=O)(COC(C)C[N]1C=NC2=C1N=CN=C2N)OCOC(=O)OC(C)C.OC(=O)/C=C/C(O)=O",1.729,14,1,19]
["S1401","Tenofovir","e9","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","Antiviral,COVID-19,Reverse Transcriptase","Microbiology","Tenofovir (GS-1278) blocks reverse transcriptase and hepatitis B virus infections.",287.21,"147127-20-6",{"v":4,"d":"4.00"},13.93,{"v":2,"d":"2.00"},6.96,"http://selleckchem.com/products/Tenofovir.html","C9H14N5O4P","free base","GS-1278","CC(C[N]1C=NC2=C(N)N=CN=C12)OC[P](O)(O)=O",-0.772,4,1,5]
["S1403","Tigecycline (GAR-936)","f9","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.4;EP9.4;Martindale:The Extra Pharmacopoeia","Marketed","Antineoplastic and Immunosuppressive Antibiotics,Autophagy,Bacterial","Microbiology","Tigecycline (Tygacil, GAR-936, WAY-GAR-936, TBG-MINO) is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline induces autophagy by downregulating the PI3K-AKT-mTOR pathway.",585.65,"220620-09-7",{"v":100,"d":"100.00"},170.75,{"v":100,"d":"100.00"},170.75,"http://selleckchem.com/products/Tigecycline.html","C29H39N5O8","free base","Tygacil, GAR-936, WAY-GAR-936, TBG-MINO","CN(C)C1C2CC3CC4=C(C(=C(NC(=O)CNC(C)(C)C)C=C4N(C)C)O)C(=O)C3=C(O)C2(O)C(=O)C(=C1O)C(N)=O",-0.381,4,6,7]
["S1404","Trilostane","g9","L3800-03","in 10mM DMSO","FDA,DMF,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Dehydrogenase","Metabolism","Trilostane (WIN 24540) is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing’s syndrome.",329.43,"13647-35-3",{"v":65,"d":"65.00"},197.31,"<1","N/A","http://selleckchem.com/products/Trilostane.html","C20H27NO3","free base","WIN 24540","CC12CCC3C(CCC45OC4C(=C(CC35C)C#N)O)C1CCC2O",2.434,1,2,0]
["S1405","Vecuronium Bromide","h9","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.2;BP2019;Martindale:The Extra Pharmacopoeia","Phase 4","AChR","Neuronal Signaling","Vecuronium Bromide (ORG NC45) is a non-depolarizing neuromuscular blocking agent, used for skeletal muscle relaxation during surgery.",637.73,"50700-72-6",{"v":100,"d":"100.00"},156.81,{"v":4,"d":"4.00"},6.27,"http://selleckchem.com/products/Vecuronium-Bromide.html","C34H57N2O4.Br","Bromide","ORG NC45","[Br-].CC(=O)OC1CC2CCC3C(CCC4(C)C3CC(C4OC(C)=O)[N+]5(C)CCCCC5)C2(C)CC1N6CCCCC6",{"v":1.73,"d":"1.730"},4,0,6]
["S1407","Bimatoprost","a10","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","USP;Martindale:The Extra Pharmacopoeia","Marketed","Prostaglandin Receptor","GPCR & G Protein","Bimatoprost(AGN 192024) is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.",415.57,"155206-00-1",{"v":36,"d":"36.00"},86.63,"<1","N/A","http://selleckchem.com/products/Bimatoprost.html","C25H37NO4","free base","AGN 192024","CCNC(=O)CCC\\C=C/CC1C(O)CC(O)C1/C=C/C(O)CCC2=CC=CC=C2",{"v":3.03,"d":"3.030"},1,4,12]
["S1408","Linezolid (PNU-100766)","b10","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics","Microbiology","Linezolid (Zyvoxid, Zyvoxam,PNU-100766) is a synthetic antibiotic used for the treatment of serious infections.",337.35,"165800-03-3",{"v":67,"d":"67.00"},198.61,"<1","N/A","http://selleckchem.com/products/Linezolid(Zyvox).html","C16H20FN3O4","free base","Zyvoxid, Zyvoxam,PNU-100766","CC(=O)NCC1CN(C(=O)O1)C2=CC=C(N3CCOCC3)C(=C2)F",0.894,4,1,4]
["S1409","Alfuzosin HCl","c10","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;EP9.1;BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Alfuzosin HCI(SL 77499 HCl)  is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH).",425.91,"81403-68-1",{"v":85,"d":"85.00"},199.57,{"v":85,"d":"85.00"},199.57,"http://selleckchem.com/products/Alfuzosin-hydrochloride.html","C19H27N5O4.HCl","Hydrochloride","SL 77499 HCl","Cl.COC1=C(OC)C=C2C(=NC(=NC2=C1)N(C)CCCNC(=O)C3CCCO3)N",{"v":1.8,"d":"1.800"},6,2,8]
["S1415","Clopidogrel (SR-25990C) Bisulfate","d10","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","P2 Receptor","Neuronal Signaling","Clopidogrel Bisulfate (SR-25990C, Clopidogrel hydrogen sulfate, Iscover, Plavix) is an oral, thienopyridine class antiplatelet agent.",{"v":419.9,"d":"419.90"},"120202-66-6",{"v":83,"d":"83.00"},197.67,{"v":78,"d":"78.00"},185.76,"http://selleckchem.com/products/Clopidogrel-bisulfate.html","C16H16ClNO2S.H2SO4","Bisulfate","SR-25990C, Clopidogrel hydrogen sulfate, Iscover, Plavix","COC(=O)C(N1CCC2=C(C1)C=CS2)C3=C(Cl)C=CC=C3.O[S](O)(=O)=O",3.128,2,0,4]
["S1425","Ranolazine 2HCl","e10","L3800-03","in 10mM DMSO","FDA,DMF,EMA,NDC","Martindale:The Extra Pharmacopoeia","Marketed","Calcium Channel","Transmembrane Transporters","Ranolazine 2HCl (RS-43285,RS 43285-193,Ranexa, renolazine,Ranolazine dihydrochloride) is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina.",500.46,"95635-56-6",{"v":100,"d":"100.00"},199.82,{"v":100,"d":"100.00"},199.82,"http://selleckchem.com/products/Ranolazine-dihydrochloride.html","C24H33N3O4.2HCl","Dihydrochloride","RS-43285,RS 43285-193,Ranexa, renolazine,Ranolazine dihydrochloride","Cl.Cl.COC1=CC=CC=C1OCC(O)CN2CCN(CC2)CC(=O)NC3=C(C)C=CC=C3C",3.755,3,2,9]
["S1426","Repaglinide","f10","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Potassium Channel","Transmembrane Transporters","Repaglinide (AG-EE 623 ZW) is a potassium channel blocker, which lowers blood glucose by stimulating the release of insulin from the pancreas, used the treatment of type II diabetes.",452.59,"135062-02-1",{"v":91,"d":"91.00"},201.06,"<1","N/A","http://selleckchem.com/products/Repaglinide.html","C27H36N2O4","free base","AG-EE 623 ZW","CCOC1=C(C=CC(=C1)CC(=O)NC(CC(C)C)C2=CC=CC=C2N3CCCCC3)C(O)=O",5.307,3,1,10]
["S1430","Rolipram (ZK-62711)","g10","L3800-03","in 10mM DMSO","DMF","N/A","N/A","PDE","Metabolism","The PDE4 selective inhibitor, Rolipram (ZK-62711, SB 95952), inhibited immunopurified PDE4B and PDE4D activities similarly, with IC50 values of approx. 130 nM and 240 nM respectively; an anti-inflammatory agent.",275.34,"61413-54-5",{"v":55,"d":"55.00"},199.75,"<1","N/A","http://selleckchem.com/products/Rolipram.html","C16H21NO3","free base","ZK-62711, SB 95952","COC1=C(OC2CCCC2)C=C(C=C1)C3CNC(=O)C3",2.349,3,1,4]
["S1431","Sildenafil Citrate","h10","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.2;BP2019;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","PDE","Metabolism","Sildenafil Citrate, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), is a well-tolerated and highly effective treatment for erectile dysfunction.",{"v":666.7,"d":"666.70"},"171599-83-0",{"v":20,"d":"20.00"},{"v":30,"d":"30.00"},"<1","N/A","http://selleckchem.com/products/Sildenafil-citrate.html","C22H30N6O4S.C6H8O7","Citrate","N/A","CCCC1=N[N](C)C2=C1N=C(NC2=O)C3=CC(=CC=C3OCC)[S](=O)(=O)N4CCN(C)CC4.OC(=O)CC(O)(CC(O)=O)C(O)=O",-2.107,9,1,12]
["S1432","Sumatriptan Succinate","a11","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Phase 2","5-HT Receptor","Neuronal Signaling","Sumatriptan Succinate (GR 43175) is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches.",413.49,"103628-48-4",{"v":83,"d":"83.00"},200.73,{"v":83,"d":"83.00"},200.73,"http://selleckchem.com/products/Sumatriptan-succinate.html","C14H21N3O2S.C4H6O4","Succinate","GR 43175","CN[S](=O)(=O)CC1=CC=C2[NH]C=C(CCN(C)C)C2=C1.OC(=O)CCC(O)=O",-1.958,4,2,9]
["S1435","Tamsulosin hydrochloride","b11","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","N/A","Adrenergic Receptor","Neuronal Signaling","Tamsulosin (Flomax) hydrochloride is an antagonist of alpha1A adrenoceptors in the prostate.",444.97,"106463-17-6",{"v":89,"d":"89.00"},200.01,"<1","N/A","https://www.selleckchem.com/products/Tamsulosin-hydrochloride.html","C20H28N2O5S.HCl","HCl","Flomax hydrochloride","CCOC1=C(OCCNC(C)CC2=CC=C(OC)C(=C2)[S](N)(=O)=O)C=CC=C1",2.719,5,2,11]
["S1437","Tizanidine HCl","c11","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","Adrenergic Receptor","Neuronal Signaling","Tizanidine HCl (DS 103-282) is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.",290.17,"64461-82-1",{"v":10,"d":"10.00"},34.46,{"v":15,"d":"15.00"},51.69,"http://selleckchem.com/products/Tizanidine-hydrochloride.html","C9H8ClN5S.HCl","Hydrochloride","DS 103-282","Cl.ClC1=C(NC2=NCCN2)C3=NSN=C3C=C1",2.199,3,2,2]
["S1438","Topiramate","d11","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Carbonic Anhydrase","Metabolism","Topiramate (MCN 4853, RWJ 17021) is a mutil-targeted inhibitor, including voltage-gated sodium channel and calcium channel, AMPA/kainate receptor and carbonic anhydrase, used to treat epilepsy.",339.36,"97240-79-4",{"v":68,"d":"68.00"},200.38,"<1","N/A","http://selleckchem.com/products/Topiramate.html","C12H21NO8S","free base","MCN 4853, RWJ 17021","CC1(C)OC2COC3(CO[S](N)(=O)=O)OC(C)(C)OC3C2O1",-1.932,6,1,3]
["S1439","Tranilast (SB 252218)","e11","L3800-03","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","Immunology & Inflammation related","Immunology & Inflammation","Tranilast (SB 252218, MK-341, Rizaben, MK 341, Tranpro) is an antiallergic drug by inhibiting lipid mediator and cytokine release from inflammatory cells, used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.",327.33,"53902-12-8",{"v":66,"d":"66.00"},201.63,"<1","N/A","http://selleckchem.com/products/Tranilast.html","C18H17NO5","free base","SB 252218, MK-341, Rizaben, MK 341, Tranpro","COC1=C(OC)C=C(\\C=C\\C(=O)NC2=CC=CC=C2C(O)=O)C=C1",2.679,4,1,6]
["S1441","Venlafaxine HCl","f11","L3800-03","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Serotonin Transporter","Neuronal Signaling","Venlafaxine HCl(Wy 453 HCl) is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.",313.86,"99300-78-4",{"v":55.5,"d":"55.50"},176.83,{"v":55.5,"d":"55.50"},176.83,"http://selleckchem.com/products/Venlafaxine-hydrochloride.html","C17H27NO2.HCl","Hydrochloride","Wy 453 HCl","Cl.COC1=CC=C(C=C1)C(CN(C)C)C2(O)CCCCC2",3.404,1,0,5]
["S1442","Voriconazole (UK-109496)","g11","L3800-03","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Fungal,P450 (e.g. CYP17)","Metabolism","Voriconazole (Vfend,UK-109496) is a new triazole derivative similar to fluconazole and itraconazole that acts by inhibiting fungal cytochrome P-450-dependent, 14-alpha-sterol demethylase-mediated synthesis of ergosterol.",349.31,"137234-62-9",{"v":70,"d":"70.00"},{"v":200.4,"d":"200.40"},"<1","N/A","http://selleckchem.com/products/Voriconazole.html","C16H14F3N5O","free base","Vfend,UK-109496","CC(C1=NC=NC=C1F)C(O)(C[N]2C=NC=N2)C3=CC=C(F)C=C3F",2.071,4,0,5]
["S1443","Zileuton (A-64077)","h11","L3800-03","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Ferroptosis,Lipoxygenase","Metabolism","Zileuton (A-64077, Abbott 64077, ZYFLO) is an orally active inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation, used to decrease the symptoms of asthma. Zileuton induces apoptosis while inhibits ferroptosis.",236.29,"111406-87-2",{"v":47,"d":"47.00"},198.91,"<1","N/A","http://selleckchem.com/products/Zileuton.html","C11H12N2O2S","free base","A-64077, Abbott 64077, ZYFLO","CC(N(O)C(N)=O)C1=CC2=CC=CC=C2S1",2.184,1,1,2]
["S1444","Ziprasidone HCl","a2","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Ziprasidone HCl (CP-88059) is a novel and potent dopamine and serotonin (5-HT) receptor antagonist, used in the treatment of schizophrenia and bipolar disorder.",{"v":449.4,"d":"449.40"},"122883-93-6",{"v":90,"d":"90.00"},200.27,"<1","N/A","http://selleckchem.com/products/Ziprasidone-hydrochloride.html","C21H21ClN4OS.HCl","Hydrochloride","CP-88059","Cl.ClC1=CC2=C(CC(=O)N2)C=C1CCN3CCN(CC3)C4=NSC5=C4C=CC=C5",4.641,2,1,4]
["S1445","Zonisamide","b2","L3800-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","Sodium Channel","Transmembrane Transporters","Zonisamide (Zonegran,CI-912,AD 810) is a voltage-dependent sodium channel and T-type calcium channel blocker, used as an antiepileptic drug.",212.23,"68291-97-4",{"v":42,"d":"42.00"},{"v":197.9,"d":"197.90"},"<1","N/A","http://selleckchem.com/products/Zonisamide.html","C8H8N2O3S","free base","Zonegran,CI-912,AD 810","N[S](=O)(=O)CC1=NOC2=CC=CC=C12",0.411,4,1,2]
["S1452","Ispinesib (SB-715992)","c2","L3800-04","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,Kinesin","Cytoskeletal Signaling","Ispinesib (SB-715992, CK0238273) is a potent, specific and reversible inhibitor of kinesin spindle protein (KSP) with Ki app of 1.7 nM in a cell-free assay, no inhibition to CENP-E, RabK6, MCAK, MKLP1, KHC or Kif1A. Ispinesib induces mitotic arrest and apoptotic cell death.",517.06,"336113-53-2",{"v":103,"d":"103.00"},{"v":199.2,"d":"199.20"},"<1","N/A","http://selleckchem.com/products/Ispinesib-mesilate(SB-715992).html","C30H33ClN4O2","free base","CK0238273","CC(C)C(N(CCCN)C(=O)C1=CC=C(C)C=C1)C2=NC3=C(C=CC(=C3)Cl)C(=O)N2CC4=CC=CC=C4",5.259,3,1,9]
["S1453","Tipifarnib (R115777)","d2","L3800-04","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia","Phase 3","FTase,Transferase","Metabolism","Tipifarnib (R115777, IND 58359) is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM, its anti-proliferative effects are most prominent in H-ras or N-ras mutant cells. Phase 3.",{"v":489.4,"d":"489.40"},"192185-72-1",{"v":14,"d":"14.00"},28.61,"<1","N/A","http://selleckchem.com/products/Tipifarnib(R115777).html","C27H22Cl2N4O","free base","IND 58359","C[N]1C=NC=C1C(N)(C2=CC=C(Cl)C=C2)C3=CC4=C(C=C3)N(C)C(=O)C=C4C5=CC(=CC=C5)Cl",4.808,2,1,4]
["S1455","Cilomilast","e2","L3800-04","in 10mM DMSO","N/A","N/A","Phase 3","PDE","Metabolism","Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.",343.42,"153259-65-5",{"v":69,"d":"69.00"},200.92,"<1","N/A","http://selleckchem.com/products/Cilomilast(SB-207499).html","C20H25NO4","free base","SB-207499","COC1=C(OC2CCCC2)C=C(C=C1)C3(CCC(CC3)C(O)=O)C#N",4.174,3,0,5]
["S1456","Zibotentan (ZD4054)","f2","L3800-04","in 10mM DMSO","N/A","N/A","Phase 2/3","Endothelin Receptor","GPCR & G Protein","Zibotentan (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.",424.43,"186497-07-4",{"v":24,"d":"24.00"},56.55,"<1","N/A","http://selleckchem.com/products/Zibotentan(ZD4054).html","C19H16N6O4S","free base","N/A","COC1=NC(=CN=C1N[S](=O)(=O)C2=CC=CN=C2C3=CC=C(C=C3)C4=NN=CO4)C",1.456,9,1,6]
["S1457","Atazanavir (BMS-232632) Sulfate","g2","L3800-04","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","EP9.7;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","HIV Protease","Proteases","Atazanavir Sulfate (BMS-232632-05, Reyataz) is a HIV protease inhibitor with Ki of 2.66 nM in a cell-free assay.",802.93,"229975-97-7",{"v":104,"d":"104.00"},129.53,"<1","N/A","http://selleckchem.com/products/Atazanavir.html","C38H52N6O7.H2SO4","Sulfate","BMS-232632-05, Reyataz","COC(=O)NC(C(=O)NC(CC1=CC=CC=C1)C(O)CN(CC2=CC=C(C=C2)C3=NC=CC=C3)NC(=O)C(NC(=O)OC)C(C)(C)C)C(C)(C)C.O[S](O)(=O)=O",4.083,7,5,18]
["S1458","Neflamapimod (VX-745)","h2","L3800-04","in 10mM DMSO","DMF","N/A","Phase 2","p38 MAPK","MAPK","Neflamapimod (VX-745) is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ.",436.26,"209410-46-8",{"v":15,"d":"15.00"},34.38,"<1","N/A","http://selleckchem.com/products/VX-745.html","C19H9Cl2F2N3OS","free base","N/A","FC1=CC(=C(SC2=NN3C=NC(=O)C(=C3C=C2)C4=C(Cl)C=CC=C4Cl)C=C1)F",5.342,3,0,3]
["S1462","AZD6482","a3","L3800-04","in 10mM DMSO","N/A","N/A","Phase 1","PI3K","PI3K/Akt/mTOR","AZD6482 (KIN-193) is a PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ in cell-free assays. Phase 1.",408.45,"1173900-33-8",{"v":82,"d":"82.00"},200.76,"<1","N/A","http://selleckchem.com/products/azd6482.html","C22H24N4O4","free base","KIN-193","CC(NC1=CC=CC=C1C(O)=O)C2=CC(=CN3C(=O)C=C(N=C23)N4CCOCC4)C",2.003,4,1,5]
["S1465","Moxifloxacin (BAY12-8039) HCl","b3","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.8;BP2019;Martindale:The Extra Pharmacopoeia","Marketed","Topoisomerase","DNA Damage/DNA Repair","Moxifloxacin (Avelox, Avalox,BAY12-8039 HCl) is a fourth-generation synthetic fluoroquinolone antibacterial agent.",437.89,"186826-86-8",{"v":87,"d":"87.00"},198.68,{"v":60,"d":"60.00"},137.02,"https://www.selleckchem.com/products/Moxifloxacin-hcl.html","C21H24FN3O4.HCl","Hydrochloride","Avelox, Avalox,BAY12-8039 HCl","Cl.COC1=C2N(C=C(C(O)=O)C(=O)C2=CC(=C1N3CC4CCCNC4C3)F)C5CC5",{"v":-0.32,"d":"-0.320"},3,1,4]
["S1467","Doxercalciferol","c3","L3800-04","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","Vitamin","Metabolism","Doxercalciferol (1α-hydroxyvitamin D2) is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.",412.65,"54573-75-0",{"v":83,"d":"83.00"},201.14,"<1","N/A","http://selleckchem.com/products/Doxercalciferol(Hectorol).html","C28H44O2","free base","1α-hydroxyvitamin D2","CC(C)C(C)/C=C/C(C)C1CCC2C(/CCCC12C)=C/C=C/3CC(O)CC(O)C3=C",6.337,0,2,5]
["S1468","Alfacalcidol","d3","L3800-04","in 10mM DMSO","CFDA,PMDA,HMA","BP2019;EP9.2;KP Ⅹ;Martindale:The Extra Pharmacopoeia","Phase 4","Vitamin","Metabolism","Alfacalcidol (1-hydroxycholecalciferol) is a non-selective VDR activator medication.",400.64,"41294-56-8",{"v":80,"d":"80.00"},199.68,"<1","N/A","http://selleckchem.com/products/Alfacalcidol.html","C27H44O2","free base","1-hydroxycholecalciferol","CC(C)CCCC(C)C1CCC2/C(CCCC12C)=C\\C=C3/CC(O)CC(O)C3=C",{"v":6.53,"d":"6.530"},0,2,6]
["S1470","Orantinib (SU6668)","e3","L3800-04","in 10mM DMSO","N/A","N/A","Phase 3","PDGFR","Protein Tyrosine Kinase","Orantinib (TSU-68, SU6668) has greatest potency against PDGFR autophosphorylation with Ki of 8 nM in a cell-free assay, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2; does not inhibit EGFR. Phase 3.",310.35,"252916-29-3",{"v":62,"d":"62.00"},199.77,"<1","N/A","http://selleckchem.com/products/TSU-68(SU6668).html","C18H18N2O3","free base","TSU-68","CC1=C(CCC(O)=O)C(=C([NH]1)/C=C/2C(=O)NC3=CC=CC=C23)C",2.868,2,2,4]
["S1472","Safinamide Mesylate","f3","L3800-04","in 10mM DMSO","FDA,DMF,EMA,NDC","N/A","Marketed","MAO","Metabolism","Safinamide Mesylate (PNU-151774E, FCE28073) is mesylate salt of Safinamide, selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A. Phase 3.",398.45,"202825-46-5",{"v":80,"d":"80.00"},200.78,{"v":80,"d":"80.00"},200.78,"http://selleckchem.com/products/Safinamide-mesilate.html","C17H19FN2O2.CH4O3S","Mesylate","PNU-151774E,FCE28073","CC(NCC1=CC=C(OCC2=CC(=CC=C2)F)C=C1)C(N)=O.C[S](O)(=O)=O",2.064,2,2,7]
["S1475","Pimasertib (AS-703026)","g3","L3800-04","in 10mM DMSO","N/A","N/A","Phase 2","MEK","MAPK","Pimasertib (AS-703026, MSC1936369B, SAR 245509) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines. Phase 2.",{"v":431.2,"d":"431.20"},"1236699-92-5",{"v":86,"d":"86.00"},199.44,"<1","N/A","http://selleckchem.com/products/AS703026.html","C15H15FIN3O3","free base","MSC1936369B, SAR 245509","OCC(O)CNC(=O)C1=CC=NC=C1NC2=C(F)C=C(I)C=C2",1.171,2,4,6]
["S1482","Daclatasvir (BMS-790052)","h3","L3800-04","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","HCV Protease","Proteases","Daclatasvir (BMS-790052, EBP883) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. Phase 3.",738.88,"1009119-64-5",{"v":148,"d":"148.00"},{"v":200.3,"d":"200.30"},"<1","N/A","http://selleckchem.com/products/BMS-790052.html","C40H50N8O6","free base","EBP883","COC(=O)NC(C(C)C)C(=O)N1CCCC1C2=NC=C([NH]2)C3=CC=C(C=C3)C4=CC=C(C=C4)C5=CN=C([NH]5)C6CCCN6C(=O)C(NC(=O)OC)C(C)C",5.048,8,4,13]
["S1483","Iloperidone","a4","L3800-04","in 10mM DMSO","FDA,DMF,EMA,NDC","USP","Marketed","5-HT Receptor","Neuronal Signaling","Iloperidone (HP873) is a dopamine (D2)/serotonin (5-HT2) receptor antagonist, used for the treatment of schizophrenia.",426.48,"133454-47-4",{"v":27,"d":"27.00"},63.31,"<1","N/A","http://selleckchem.com/products/Iloperidone(Fanapt).html","C24H27FN2O4","free base","HP873","COC1=C(OCCCN2CCC(CC2)C3=NOC4=C3C=CC(=C4)F)C=CC(=C1)C(C)=O",4.016,5,0,8]
["S1485","HMN-214","b4","L3800-04","in 10mM DMSO","DMF","N/A","N/A","PLK","Cell Cycle","HMN-214 is a prodrug of HMN-176, which alters the cellular spatial orientation of Plk1.",424.47,"173529-46-9",{"v":12,"d":"12.00"},28.27,"<1","N/A","http://selleckchem.com/products/HMN-214.html","C22H20N2O5S","free base","N/A","COC1=CC=C(C=C1)[S](=O)(=O)N(C(C)=O)C2=C(C=CC=C2)\\C=C\\C3=CC=[N+]([O-])C=C3",2.282,4,0,6]
["S1486","AEE788 (NVP-AEE788)","c4","L3800-04","in 10mM DMSO","N/A","N/A","Phase 2","EGFR,HER2,VEGFR","Protein Tyrosine Kinase","AEE788 (NVP-AEE788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1R, PKCα and CDK1. Phase 1/2.",440.58,"497839-62-0",{"v":88,"d":"88.00"},199.74,"<1","N/A","http://selleckchem.com/products/AEE788.html","C27H32N6","free base","N/A","CCN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(NC(C)C5=CC=CC=C5)N=CN=C4[NH]3",5.042,2,2,7]
["S1487","PHA-793887","d4","L3800-04","in 10mM DMSO","N/A","N/A","Phase 1","Apoptosis related,CDK","Cell Cycle","PHA-793887 is a novel and potent inhibitor of CDK2, CDK5 and CDK7 with IC50 of 8 nM, 5 nM and 10 nM. It is greater than 6-fold more selective for CDK2, 5, and 7 than CDK1, 4, and 9. PHA-793887 induces cell-cycle arrest and apoptosis. Phase 1.",361.48,"718630-59-2",{"v":72,"d":"72.00"},199.18,"<1","N/A","http://selleckchem.com/products/PHA-793887.html","C19H31N5O2","free base","N/A","CC(C)CC(=O)NC1=N[NH]C2=C1CN(C(=O)C3CCN(C)CC3)C2(C)C",1.895,3,2,4]
["S1488","Naratriptan HCl","e4","L3800-04","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor","Neuronal Signaling","Naratriptan HCl is a triptan agent that is used for the treatment of migraine headaches.",371.93,"143388-64-1",{"v":74,"d":"74.00"},198.96,{"v":22,"d":"22.00"},59.15,"http://selleckchem.com/products/Naratriptan(Amerge).html","C17H25N3O2S.HCl","Hydrochloride","N/A","Cl.CN[S](=O)(=O)CCC1=CC=C2[NH]C=C(C3CCN(C)CC3)C2=C1",2.435,2,2,5]
["S1490","Ponatinib (AP24534)","f4","L3800-04","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Autophagy,Bcr-Abl,FGFR,PDGFR,Src,VEGFR","Angiogenesis","Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively. Ponatinib (AP24534) inhibits autophagy.",532.56,"943319-70-8",{"v":30,"d":"30.00"},56.33,"<1","N/A","http://selleckchem.com/products/AP24534.html","C29H27F3N6O","free base","AP24534","CN1CCN(CC1)CC2=C(C=C(NC(=O)C3=CC(=C(C)C=C3)C#CC4=CN=C5C=CC=N[N]45)C=C2)C(F)(F)F",4.884,3,1,7]
["S1491","Fludarabine (NSC 118218)","g4","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,DNA/RNA Synthesis,Nucleoside Analog/Antimetabolite,STAT","JAK/STAT","Fludarabine (NSC 118218, FaraA, Fludarabinum) is a STAT1 activation inhibitor which causes a specific depletion of STAT1 protein (and mRNA) but not of other STATs. Also a DNA synthesis inhibitor in vascular smooth muscle cells. Fludarabine induces apoptosis.",285.23,"21679-14-1",{"v":57,"d":"57.00"},199.84,"<1","N/A","http://selleckchem.com/products/Fludarabine(Fludara).html","C10H12FN5O4","Free Base","FaraA, Fludarabinum, NSC 118218","NC1=NC(=NC2=C1N=C[N]2C3OC(CO)C(O)C3O)F",-1.312,4,4,2]
["S1497","Pralatrexate (NSC 754230)","h4","L3800-04","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Apoptosis related,DHFR","Metabolism","Pralatrexate (NSC 754230) is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines. Pralatrexate induces tumor cell apoptosis.",477.47,"146464-95-1",{"v":28,"d":"28.00"},58.64,"<1","N/A","http://selleckchem.com/products/Pralatrexate(Folotyn).html","C23H23N7O5","free base","NSC 754230","NC1=NC(=C2N=C(CC(CC#C)C3=CC=C(C=C3)C(=O)NC(CCC(O)=O)C(O)=O)C=NC2=N1)N",{"v":1.94,"d":"1.940"},7,3,10]
["S1499","Cefaclor","a5","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Antibiotics","Microbiology","Cefaclor (Cefachlor, Cefaclorum) is a cephalosporin antibiotic.",385.82,"70356-03-5",{"v":11,"d":"11.00"},28.51,"<1","N/A","http://selleckchem.com/products/Cefaclor-(Ceclor).html","C15H14ClN3O4S.H2O","monohydrate","Cefachlor, Cefaclorum","O.NC(C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)Cl)C3=CC=CC=C3",{"v":-2.54,"d":"-2.540"},3,2,4]
["S1500","Betamethasone","b5","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP38-NF33;BP2013;JP16;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Glucocorticoid Receptor","Endocrinology & Hormones","Betamethasone (NSC-39470, SCH-4831) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.",392.46,"378-44-9",{"v":79,"d":"79.00"},201.29,"<1","N/A","http://selleckchem.com/products/Betamethasone-(Celestone).html","C22H29FO5","Free Base","NSC-39470, SCH-4831","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO",1.708,2,2,2]
["S1501","Mycophenolate mofetil (RS-61443)","c5","L3800-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Dehydrogenase","Metabolism","Mycophenolate Mofetil (RS 61443, Mycophenolic acid morpholinoethyl ester, CellCept, TM-MMF) is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively. Mycophenolate Mofetil induces caspase-dependent apoptosis and cell cycle inhibition in multiple myeloma cells.",433.49,"128794-94-5",{"v":86,"d":"86.00"},198.39,"<1","N/A","http://selleckchem.com/products/Mycophenolate-mofetil-(CellCept).html","C23H31NO7","free base","Mycophenolic acid morpholinoethyl ester, CellCept, RS 61443, TM-MMF","COC1=C(C)C2=C(C(=O)OC2)C(=C1C\\C=C(C)\\CCC(=O)OCCN3CCOCC3)O",3.209,6,1,10]
["S1504","Dyphylline","d5","L3800-04","in 10mM DMSO","FDA,DMF","USP42-NF37","N/A","PDE","Metabolism","Dyphylline (Diprophylline) is a xanthine derivative with bronchodilator and vasodilator effects.",254.24,"479-18-5",{"v":51,"d":"51.00"},{"v":200.6,"d":"200.60"},{"v":51,"d":"51.00"},{"v":200.6,"d":"200.60"},"http://selleckchem.com/products/Dyphylline(Dilor).html","C10H14N4O4","free base","Diprophylline","CN1C(=O)N(C)C2=C([N](CC(O)CO)C=N2)C1=O",-1.151,3,2,3]
["S1505","Aztreonam","e5","L3800-04","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA","USP42-NF37;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics,Bacterial","Microbiology","Aztreonam (SQ 26776) is a synthetic monocyclic beta-lactam antibiotic, used to treat Gram-negative aerobic bacteria infection.",435.43,"78110-38-0",{"v":87,"d":"87.00"},{"v":199.8,"d":"199.80"},{"v":11,"d":"11.00"},25.26,"http://selleckchem.com/products/Aztreonam(Azactam).html","C13H17N5O8S2","free base","SQ 26776","CC1C(NC(=O)\\C(=N/OC(C)(C)C(O)=O)C2=CSC(=N2)N)C(=O)N1[S](O)(=O)=O",-1.035,6,2,7]
["S1508","Alprostadil","f5","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","PGES","Endocrinology & Hormones","Alprostadil (Prostaglandin-E1, PGE1, Edex, Muse, Liprostin) is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It is a Prostaglandin Analog and Prostaglandin E1 Agonist.",354.48,"745-65-3",{"v":71,"d":"71.00"},200.29,"<1","N/A","http://selleckchem.com/products/Alprostadil(Caverject).html","C20H34O5","free base","Prostaglandin-E1, PGE1, Edex, Muse, Liprostin","CCCCCC(O)/C=C/C1C(O)CC(=O)C1CCCCCCC(O)=O",3.644,2,2,13]
["S1511","Lactulose","g5","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.8;BP2019;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 4","Others","Others","Lactulose, a disaccharide composed of galactose and fructose, is a stimulator of health-promoting bacterium growth in the gastrointestinal tract, used to treat chronic constipation and hepatic encephalopathy.",{"v":342.3,"d":"342.30"},"4618-18-2",{"v":68,"d":"68.00"},198.66,{"v":68,"d":"68.00"},198.66,"http://selleckchem.com/products/Lactulose(Enulose).html","C12H22O11","free base","N/A","OCC(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)C(=O)CO",-4.621,3,8,8]
["S1512","Tadalafil (IC351)","h5","L3800-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Preregistration","PDE","Metabolism","Tadalafil (IC351) is a PDE-5 inhibitor with IC50 of 1.8 nM in a cell-free assay. Tadalafil is at least 9000 times more selective for PDE5 than most of the other families of PDEs, with the exception of PDE11. It can partial inhibits PDE11",{"v":389.4,"d":"389.40"},"171596-29-5",{"v":78,"d":"78.00"},200.31,"<1","N/A","http://selleckchem.com/products/Tadalafil(Cialis).html","C22H19N3O4","free base","IC351","CN1CC(=O)N2C(CC3=C([NH]C4=C3C=CC=C4)C2C5=CC=C6OCOC6=C5)C1=O",2.183,4,1,1]
["S1514","Cyclosporine","a6","L3800-04","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","Phase 2/3","Immunology & Inflammation related,phosphatase","Metabolism","Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.",1202.61,"79217-60-0",{"v":100,"d":"100.00"},83.15,"<1","N/A","http://selleckchem.com/products/Cyclosporine.html","C62H111N11O12","free base","Neoral","CCC1NC(=O)C(C(O)C(C)C\\C=C\\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C",4.333,11,5,15]
["S1515","Pracinostat (SB939)","b6","L3800-04","in 10mM DMSO","N/A","N/A","Phase 3","Apoptosis related,HDAC","Cytoskeletal Signaling","Pracinostat (SB939) is a potent pan-HDAC inhibitor with IC50 of 40-140 nM with exception for HDAC6. It has no activity against the class III isoenzyme SIRT I. Pracinostat (SB939) induces apoptosis in tumor cells. Phase 2.",358.48,"929016-96-6",{"v":72,"d":"72.00"},200.85,"<1","N/A","http://selleckchem.com/products/SB939.html","C20H30N4O2","free base","N/A","CCCCC1=NC2=CC(=CC=C2[N]1CCN(CC)CC)\\C=C\\C(=O)NO",{"v":3.71,"d":"3.710"},2,1,10]
["S1517","Natamycin","c6","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","Phase 2/3","Fungal","Microbiology","Natamycin (Pimaricin), a natural and versatile anti-fungal agent during fermentation by the bacterium Streptomyces natalensis, commonly found in soil; with little to no flavour interference",665.73,"7681-93-8",{"v":7,"d":"7.00"},10.51,"<1","N/A","http://selleckchem.com/products/Natamycin(Pimaricin).html","C33H47NO13","free base","Pimaricin","CC1C/C=C/C=C/C=C/C=C/C(CC2OC(O)(CC(O)CC3OC3/C=C/C(=O)O1)CC(O)C2C(O)=O)OC4OC(C)C(O)C(N)C4O",-2.824,7,5,3]
["S1524","AT7519","d6","L3800-04","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,CDK,GSK-3","Cell Cycle","AT7519 is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM. It is less potent to CDK3 and little active to CDK7. AT7519 also decrease GSK3β phosphorylation. AT7519 induces apoptosis. Phase 2.",382.24,"844442-38-2",{"v":10,"d":"10.00"},26.16,"<1","N/A","http://selleckchem.com/products/AT7519.html","C16H17Cl2N5O2","Free Base","N/A","ClC1=CC=CC(=C1C(=O)NC2=C[NH]N=C2C(=O)NC3CCNCC3)Cl",1.599,3,4,4]
["S1525","Adavosertib (MK-1775)","e6","L3800-04","in 10mM DMSO","N/A","N/A","Phase 2","Wee1","Cell Cycle","Adavosertib (MK-1775, AZD1775) is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM in a cell-free assay; hinders G2 DNA damage checkpoint. Phase 2.",{"v":500.6,"d":"500.60"},"955365-80-7",{"v":80,"d":"80.00"},159.81,"N/A","N/A","http://selleckchem.com/products/MK-1775.html","C27H32N8O2","free base","AZD1775","CN1CCN(CC1)C2=CC=C(NC3=NC4=C(C=N3)C(=O)N(CC=C)N4C5=NC(=CC=C5)C(C)(C)O)C=C2",4.158,4,1,7]
["S1526","Quizartinib (AC220)","f6","L3800-04","in 10mM DMSO","N/A","N/A","Preregistration","Apoptosis related,FLT3,Target Protein Ligand","Angiogenesis","Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Quizartinib (AC220) induces apoptosis of tumor cells. Phase 3.",560.67,"950769-58-1",{"v":33,"d":"33.00"},58.86,"<1","N/A","http://selleckchem.com/products/AC-220.html","C29H32N6O4S","free base","N/A","CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=C[N]4C(=N3)SC5=CC(=CC=C45)OCCN6CCOCC6",5.064,6,2,8]
["S1528","LY2811376","g6","L3800-04","in 10mM DMSO","N/A","N/A","Phase 1","BACE,Beta Amyloid","Proteases","LY2811376 is the first orally available non-peptidic β-secretase(BACE1) inhibitor with IC50 of 239 nM-249 nM, that act to decrease Aβ secretion with EC50 of 300 nM, demonstrated to have 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases including cathepsin D, pepsin, or renin. Phase 1.",320.36,"1194044-20-6",{"v":16,"d":"16.00"},49.94,"<1","N/A","http://selleckchem.com/products/LY2811376.html","C15H14F2N4S","free base","N/A","CC1(CCSC(=N1)N)C2=CC(=C(F)C=C2F)C3=CN=CN=C3",2.478,3,1,2]
["S1532","AZD7762","h6","L3800-04","in 10mM DMSO","N/A","N/A","Phase 1","Chk","Cell Cycle","AZD7762 is a potent and selective inhibitor of Chk1 with IC50 of 5 nM in a cell-free assay. It is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck. Phase 1.",362.42,"860352-01-8",{"v":50,"d":"50.00"},137.96,"<1","N/A","http://selleckchem.com/products/AZD7762.html","C17H19FN4O2S","free base","N/A","NC(=O)NC1=C(SC(=C1)C2=CC(=CC=C2)F)C(=O)NC3CCCNC3",2.009,2,4,4]
["S1533","R406 (free base)","a7","L3800-04","in 10mM DMSO","N/A","N/A","Marketed","Apoptosis related,FLT3,Syk","Angiogenesis","R406 (free base) is a potent Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. R406 (free base) triggers apoptosis. Phase 1.",470.45,"841290-80-0",{"v":21,"d":"21.00"},44.64,"<1","N/A","http://selleckchem.com/products/R406(free-base).html","C22H23FN6O5","free base","N/A","COC1=C(OC)C(=CC(=C1)NC2=NC(=C(F)C=N2)NC3=NC4=C(OC(C)(C)C(=O)N4)C=C3)OC",3.881,8,3,7]
["S1537","Vadimezan (ASA404)","b7","L3800-04","in 10mM DMSO","N/A","N/A","Phase 3","Antiviral,IFN,STING,TNF-alpha,VDA","Angiogenesis","Vadimezan (ASA404, NSC 640488, DMXAA) is a vascular disrupting agents (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 μM and IC50 of 62.5 μM in cell-free assays, respectively. DMXAA (Vadimezan) is also a STING agonist with potential antineoplastic activity. DMXAA (Vadimezan) potently induces IFN-β but relatively low TNF-α expression in vitro. DMXAA (Vadimezan) has antiviral activity. Phase 3.",282.29,"117570-53-3",{"v":7,"d":"7.00"},{"v":24.8,"d":"24.80"},"<1","N/A","http://selleckchem.com/products/DMXAA(ASA404).html","C17H14O4","free base","NSC 640488, DMXAA","CC1=C(C)C2=C(C=C1)C(=O)C3=C(O2)C(=CC=C3)CC(O)=O",3.601,3,0,2]
["S1538","Telaprevir (VX-950)","c7","L3800-04","in 10mM DMSO","FDA,DMF,EMA","N/A","Marketed","COVID-19,HCV Protease","Proteases","Telaprevir (VX-950, LY-570310, MP-424) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM.",679.85,"402957-28-2",{"v":136,"d":"136.00"},200.04,"<1","N/A","http://selleckchem.com/products/Telaprevir(VX-950).html","C36H53N7O6","free base","LY-570310, MP-424,VX-950","CCCC(NC(=O)C1C2CCCC2CN1C(=O)C(NC(=O)C(NC(=O)C3=NC=CN=C3)C4CCCCC4)C(C)(C)C)C(=O)C(=O)NC5CC5",2.685,8,4,14]
["S1540","Saxagliptin (BMS-477118)","d7","L3800-04","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","N/A","Marketed","DPP","Proteases","Saxagliptin (BMS-477118, Onglyza) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.",315.41,"361442-04-8",{"v":63,"d":"63.00"},199.74,{"v":63,"d":"63.00"},199.74,"http://selleckchem.com/products/Saxagliptin(Onglyza).html","C18H25N3O2","Free Base","Onglyza,BMS-477118","NC(C(=O)N1C(CC2CC12)C#N)[C]34CC5[CH2]C(C[C](O)(C5)C3)C4",0.275,1,1,2]
["S1541","Selisistat (EX 527)","e7","L3800-04","in 10mM DMSO","N/A","N/A","Phase 2","Sirtuin","Epigenetics","Selisistat (EX 527, SEN0014196) is a potent and selective SIRT1 inhibitor with IC50 of 38 nM in a cell-free assay, exhibits >200-fold selectivity against SIRT2 and SIRT3. Phase 2.",248.71,"49843-98-3",{"v":49,"d":"49.00"},197.02,"<1","N/A","http://selleckchem.com/products/EX-527.html","C13H13ClN2O","free base","SEN0014196","NC(=O)C1CCCC2=C1[NH]C3=C2C=C(Cl)C=C3",3.149,1,2,1]
["S1547","Febuxostat","f7","L3800-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","ROS","Immunology & Inflammation","Febuxostat (TMX 67, TEI-6720) is a selective xanthine oxidase inhibitor with Ki of 0.6 nM.",316.37,"144060-53-7",{"v":63,"d":"63.00"},199.13,"<1","N/A","http://selleckchem.com/products/Febuxostat(Uloric).html","C16H16N2O3S","free base","TMX 67, TEI-6720","CC(C)COC1=C(C=C(C=C1)C2=NC(=C(S2)C(O)=O)C)C#N",3.468,3,0,5]
["S1548","Dapagliflozin (BMS-512148)","g7","L3800-04","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","SGLT","GPCR & G Protein","Dapagliflozin (BMS-512148) is a potent and selective hSGLT2 inhibitor with EC50 of 1.1 nM, exhibiting 1200-fold selectivity over hSGLT1. Phase 4.",408.87,"461432-26-8",{"v":82,"d":"82.00"},200.55,"<1","N/A","http://selleckchem.com/products/Dapagliflozin.html","C21H25ClO6","free base","BMS-512148","CCOC1=CC=C(CC2=CC(=CC=C2Cl)C3OC(CO)C(O)C(O)C3O)C=C1",2.409,2,4,6]
["S1549","Nebivolol hydrochloride (R-65824)","h7","L3800-04","in 10mM DMSO","FDA,DMF,NDC,HMA","USP;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Nebivolol HCl (R-65824) selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM.",{"v":441.9,"d":"441.90"},"152520-56-4",{"v":88,"d":"88.00"},199.14,"<1","N/A","http://selleckchem.com/products/Nebivolol(Bystolic).html","C22H25F2NO4.HCl","Hydrochloride","R-65824 hydrochloride","Cl.OC(CNCC(O)C1CCC2=C(O1)C=CC(=C2)F)C3CCC4=CC(=CC=C4O3)F",3.939,2,3,6]
["S1550","Pimobendan","a8","L3800-04","in 10mM DMSO","PMDA","USP42-NF37 ;BP2019;EP9.5;Martindale:The Extra Pharmacopoeia","Marketed","PDE","Metabolism","Pimobendan (UD-CG 115 BS) is a selective inhibitor of PDE3 with IC50 of 0.32 μM.",334.37,"74150-27-9",{"v":67,"d":"67.00"},200.38,"<1","N/A","http://selleckchem.com/products/Pimobendan(Vetmedin).html","C19H18N4O2","free base","UD-CG 115 BS","COC1=CC=C(C=C1)C2=NC3=CC(=CC=C3[NH]2)C4=NNC(=O)CC4C",2.936,4,2,3]
["S1553","Delafloxacin (ABT-492)","b8","L3800-04","in 10mM DMSO","N/A","N/A","Marketed","Anti-infection","Immunology & Inflammation","Delafloxacin (ABT-492, RX-3341, WQ-3034) is a new fluoroquinolone against 155 aerobic and 171 anaerobic pathogens.",440.76,"189279-58-1, 339591-82-1 (sodium salt)",{"v":88,"d":"88.00"},199.66,"<1","N/A","http://www.selleck.cn/products/ABT-492.html","C18H12ClF3N4O4","free base","RX-3341J, WQ-3034","NC1=C(F)C=C(F)C(=N1)N2C=C(C(O)=O)C(=O)C3=CC(=C(N4CC(O)C4)C(=C23)Cl)F",2.682,3,2,3]
["S1555","AZD8055","c8","L3800-04","in 10mM DMSO","N/A","N/A","Phase 1","Apoptosis related,Autophagy,mTOR","PI3K/Akt/mTOR","AZD8055 is a novel ATP-competitive mTOR inhibitor with IC50 of 0.8 nM in MDA-MB-468 cells with excellent selectivity (∼1,000-fold) against PI3K isoforms and ATM/DNA-PK. AZD8055 induces caspase-dependent apoptosis and also induces autophagy. Phase 1.",465.54,"1009298-09-2",{"v":50,"d":"50.00"},{"v":107.4,"d":"107.40"},"<1","N/A","http://selleckchem.com/products/AZD8055.html","C25H31N5O4","free base","N/A","COC1=C(CO)C=C(C=C1)C2=NC3=C(C=C2)C(=NC(=N3)N4CCOCC4C)N5CCOCC5C",3.274,6,1,5]
["S1557","KRN 633","d8","L3800-04","in 10mM DMSO","N/A","N/A","Phase 1","VEGFR","Protein Tyrosine Kinase","KRN 633 is an ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 170 nM/160 nM/125 nM, weakly inhibits PDGFR-α/β and c-Kit, does not block the phosphorylation of FGFR-1, EGFR or c-Met in cell.",416.86,"286370-15-8",{"v":9,"d":"9.00"},21.59,"<1","N/A","http://selleckchem.com/products/KRN-633.html","C20H21ClN4O4","free base","N/A","CCCNC(=O)NC1=CC=C(OC2=NC=NC3=CC(=C(OC)C=C23)OC)C=C1Cl",4.107,6,2,7]
["S1561","BMS-777607","e8","L3800-04","in 10mM DMSO","N/A","N/A","Phase 2","Axl,c-Met,RON,Tyro3","Protein Tyrosine Kinase","BMS-777607 (BMS 817378) is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50 of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM in cell-free assays, 40-fold more selective for Met-related targets versus Lck, VEGFR-2, and TrkA/B, and more than 500-fold greater selectivity versus all other receptor and non receptor kinases.",512.89,"1025720-94-8",{"v":47,"d":"47.00"},91.64,"<1","N/A","http://selleckchem.com/products/BMS-777607.html","C25H19ClF2N4O4","free base","BMS 817378","CCOC1=C(C(=O)NC2=CC=C(OC3=CC=NC(=C3Cl)N)C(=C2)F)C(=O)N(C=C1)C4=CC=C(F)C=C4",3.517,5,2,7]
["S1565","Lumacaftor (VX-809)","f8","L3800-04","in 10mM DMSO","FDA,EMA,NDC","N/A","N/A","CFTR","Transmembrane Transporters","Lumacaftor (VX-809, VRT 826809) acts to correct CFTR mutations common in cystic fibrosis by increasing mutant CFTR (F508del-CFTR) maturation,EC50 of 0.1 μM in fisher rat thyroid cells. Phase 3.",452.41,"936727-05-8",{"v":90,"d":"90.00"},198.93,"<1","N/A","http://selleckchem.com/products/VX-809.html","C24H18F2N2O5","free base","VRT 826809","CC1=C(N=C(NC(=O)C2(CC2)C3=CC4=C(OC(F)(F)O4)C=C3)C=C1)C5=CC=CC(=C5)C(O)=O",6.411,5,1,5]
["S1567","Pomalidomide (CC-4047)","g8","L3800-04","in 10mM DMSO","FDA,EMA,NDC,PMDA","N/A","Marketed","Apoptosis related,E3 Ligase ,E3 ligase Ligand,TNF-alpha","Ubiquitin","Pomalidomide (CC-4047) inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs. Pomalidomide can be utilized in PROTAC as a ligand for targeting E3 ligase and inhibiting the E3 ligase protein cereblon (CRBN). Pomalidomide promotes apoptosis and cell cycle arrest.",273.24,"19171-19-8",{"v":54,"d":"54.00"},197.63,"<1","N/A","http://selleckchem.com/products/Pomalidomide(CC-4047).html","C13H11N3O4","free base","CC-4047","NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1",{"v":-0.65,"d":"-0.650"},4,2,1]
["S1569","Tazarotene","h8","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia","Phase 3","Retinoid Receptor","Metabolism","Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin.",351.46,"118292-40-3",{"v":10,"d":"10.00"},28.45,"<1","N/A","http://selleckchem.com/products/Tazarotene(Avage).html","C21H21NO2S","free base","AGN190168","CCOC(=O)C1=CN=C(C=C1)C#CC2=CC3=C(SCCC3(C)C)C=C2",4.951,3,0,5]
["S1573","Fasudil (HA-1077) HCl","a9","L3800-04","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,Calcium Channel,MLCK,PKA,PKC,PKG,Rho,ROCK","Cell Cycle","Fasudil (HA-1077, AT-877), a potent and selective inhibitor of Rho kinase, displays less potent inhibiton over PKA, PKG, PKC and MLCK with Ki of 1.6, 1.6, 3.3, and 36 μM in cell-free assays, respectively. Fasudil is also a calcium channel blocker.",327.83,"105628-07-7",{"v":5,"d":"5.00"},15.25,{"v":65,"d":"65.00"},198.27,"http://selleckchem.com/products/Fasudil-HCl(HA-1077).html","C14H17N3O2S.HCl","Hydrochloride","AT-877,HA-1077 HCl","Cl.O=[S](=O)(N1CCCNCC1)C2=C3C=CN=CC3=CC=C2",{"v":0.57,"d":"0.570"},3,1,2]
["S1574","Doramapimod (BIRB 796)","b9","L3800-04","in 10mM DMSO","N/A","N/A","Phase 2","JNK,p38 MAPK,Raf,Src","MAPK","Doramapimod (BIRB 796) is a  pan-p38 MAPK inhibitor with IC50 of  38 nM, 65 nM, 200 nM and 520 nM for p38α/β/γ/δ in cell-free assays, and binds p38α with Kd of 0.1 nM in THP-1 cells, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2.",527.66,"285983-48-4",{"v":100,"d":"100.00"},189.52,"<1","N/A","http://selleckchem.com/products/BIRB-796-(Doramapimod).html","C31H37N5O3","free base","N/A","CC1=CC=C(C=C1)[N]2N=C(C=C2NC(=O)NC3=CC=C(OCCN4CCOCC4)C5=C3C=CC=C5)C(C)(C)C",5.907,4,2,8]
["S1576","Sulfasalazine (NSC 667219)","c9","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37 ;EP9.2;BP2019;KP Ⅹ;Ph.Int_6th;Martindale:The Extra Pharmacopoeia","N/A","Apoptosis related,Autophagy,COX,Ferroptosis,Immunology & Inflammation related,NF-κB,TGF-beta/Smad","Immunology & Inflammation","Sulfasalazine (NSC 667219, Azulfidine, Salazopyrin, Sulphasalazine) is a sulfa derivative of mesalazine, used as an anti-inflammatory agent to treat bowel disease and rheumatoid arthritis. Sulfasalazine is a potent and specific inhibitor of nuclear factor kappa B (NF-κB), TGF-β and COX-2. Sulfasalazine induces ferroptosis, apoptosis and autophagy.",398.39,"599-79-1",{"v":80,"d":"80.00"},200.81,"<1","N/A","http://selleckchem.com/products/Sulfasalazine(Azulfidine).html","C18H14N4O5S","free base","Azulfidine, Salazopyrin, Sulphasalazine, NSC 667219","OC(=O)C1=C(O)C=CC(=C1)N=NC2=CC=C(C=C2)[S](=O)(=O)NC3=CC=CC=N3",3.463,6,2,6]
["S1578","Candesartan (CV-11974)","d9","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","Angiotensin Receptor","GPCR & G Protein","Candesartan (CV-11974) is an angiotensin II receptor antagonist with IC50 of 0.26 nM.",440.45,"139481-59-7",{"v":88,"d":"88.00"},{"v":199.8,"d":"199.80"},"<1","N/A","http://selleckchem.com/products/Candesartan(Atacand).html","C24H20N6O3","free base","CV-11974","CCOC1=NC2=C([N]1CC3=CC=C(C=C3)C4=CC=CC=C4C5=N[NH]N=N5)C(=CC=C2)C(O)=O",4.626,6,1,7]
["S1591","Bestatin (NK421)","e9","L3800-04","in 10mM DMSO","N/A","N/A","Marketed","Immunology & Inflammation related","Immunology & Inflammation","Bestatin (Ubenimex,NK421) is a potent aminopeptidase-B and leukotriene (LT) A4 hydrolase inhibitor, used in the treatment of acute myelocytic leukemia.",308.37,"58970-76-6",{"v":4,"d":"4.00"},12.97,"<1","N/A","http://www.selleck.cn/products/Ubenimex(Bestatin).html","C16H24N2O4","Free Base","Ubenimex,NK421","CC(C)CC(NC(=O)C(O)C(N)CC1=CC=CC=C1)C(O)=O",{"v":-1.34,"d":"-1.340"},2,3,8]
["S1593","Apixaban (BMS 562247-01)","f9","L3800-04","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA","N/A","Marketed","Factor Xa","Metabolism","Apixaban (BMS 562247-01) is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively.",{"v":459.5,"d":"459.50"},"503612-47-3",{"v":18,"d":"18.00"},39.17,"<1","N/A","http://selleckchem.com/products/Apixaban(BMS-562247-01).html","C25H25N5O4","free base","BMS 562247-01","COC1=CC=C(C=C1)[N]2N=C(C(N)=O)C3=C2C(=O)N(CC3)C4=CC=C(C=C4)N5CCCCC5=O",2.865,5,1,5]
["S1594","Semagacestat (LY450139)","g9","L3800-04","in 10mM DMSO","N/A","N/A","Phase 3","Beta Amyloid,Notch,Secretase","Proteases","Semagacestat (LY450139) is a γ-secretase blocker for Aβ42, Aβ40 and Aβ38 with IC50 of 10.9 nM, 12.1 nM and 12.0 nM, also inhibits Notch signaling with IC50 of 14.1 nM in H4 human glioma cell. Phase 3.",361.44,"425386-60-3",{"v":72,"d":"72.00"},{"v":199.2,"d":"199.20"},"<1","N/A","http://selleckchem.com/products/Semagacestat(LY450139).html","C19H27N3O4","free base","N/A","CC(C)C(O)C(=O)NC(C)C(=O)NC1C(=O)N(C)CCC2=C1C=CC=C2",0.632,3,3,5]
["S1601","Reserpine","h9","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 2","VMAT","Transmembrane Transporters","Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug. Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).",608.68,"50-55-5",{"v":13,"d":"13.00"},21.36,"<1","N/A","http://selleckchem.com/products/Reserpine.html","C33H40N2O9","free base","N/A","COC1C(CC2CN3CCC4=C([NH]C5=C4C=CC(=C5)OC)C3CC2C1C(=O)OC)OC(=O)C6=CC(=C(OC)C(=C6)OC)OC",4.242,9,1,10]
["S1603","Furosemide (NSC 269420)","a10","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.4;KP Ⅹ;BP2019;Ph.Int_6th;JP17;IP2010","Phase 3","NKCC","Transmembrane Transporters","Furosemide (NSC 269420) is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used in the treatment of congestive heart failure and edema.",330.74,"54-31-9",{"v":66,"d":"66.00"},199.55,"<1","N/A","http://selleckchem.com/products/Furosemide(Lasix).html","C12H11ClN2O5S","free base","NSC 269420","N[S](=O)(=O)C1=C(Cl)C=C(NCC2=CC=CO2)C(=C1)C(O)=O",1.403,4,2,5]
["S1604","Olmesartan Medoxomil","b10","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Angiotensin Receptor","GPCR & G Protein","Olmesartan Medoxomil (CS-866,RNH-6270) is a selective angiotensin II type 1 (AT(1)) receptor antagonist, used in the treatment of high blood pressure.",558.59,"144689-63-4",{"v":89,"d":"89.00"},159.33,"<1","N/A","http://selleckchem.com/products/olmesartan-medoxomil-Benicar.html","C29H30N6O6","free base","CS-866,RNH-6270","CCCC1=NC(=C([N]1CC2=CC=C(C=C2)C3=CC=CC=C3C4=N[NH]N=N4)C(=O)OCC5=C(C)OC(=O)O5)C(C)(C)O",4.814,9,1,11]
["S1605","Cefdinir","c10","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics,Bacterial","Microbiology","Cefdinir (FK 482, PD 134393, CI-983) is an oral cephalosporin antibiotic, used to treat bacterial infections in many different parts of the body.",395.41,"91832-40-5",{"v":79,"d":"79.00"},199.79,"<1","N/A","http://selleckchem.com/products/Cefdinir(Omnicef).html","C14H13N5O5S2","free base","FK 482, PD 134393, CI-983","NC1=NC(=CS1)C(=N/O)/C(=O)NC2C3SCC(=C(N3C2=O)C(O)=O)C=C",-0.172,5,2,5]
["S1606","Clotrimazole","d10","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Antineoplastic and Immunosuppressive Antibiotics,Fungal","Microbiology","Clotrimazole (BAY b 5097, FB 5097) alters the permeability of the fungal cell wall by inhibiting the biosynthesis of ergosterol, used in the treatment of fungal infections.",344.84,"23593-75-1",{"v":11,"d":"11.00"},{"v":31.9,"d":"31.90"},"<1","N/A","http://selleckchem.com/products/Clotrimazole(Canesten).html","C22H17ClN2","free base","BAY b 5097, FB 5097","ClC1=C(C=CC=C1)C([N]2C=CN=C2)(C3=CC=CC=C3)C4=CC=CC=C4",5.222,1,0,4]
["S1607","Rizatriptan Benzoate","e10","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Registered","5-HT Receptor","Neuronal Signaling","Rizatriptan Benzoate (MK-462) is an agonist at serotonin 5-HT1B and 5-HT1D receptors, used to treat acute migraine attacks.",391.47,"145202-66-0",{"v":20,"d":"20.00"},51.09,{"v":46,"d":"46.00"},117.51,"http://selleckchem.com/products/Rizatriptan-Benzoate(Maxalt).html","C22H25N5O2","Benzoate","MK-462 Benzoate","CN(C)CCC1=C[NH]C2=C1C=C(C[N]3C=NC=N3)C=C2.OC(=O)C4=CC=CC=C4",0.492,3,1,6]
["S1608","Pyridostigmine Bromide","f10","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Phase 2","AChR","Neuronal Signaling","Pyridostigmine Bromide is a parasympathomimetic and a reversible cholinesterase inhibitor.",261.12,"101-26-8",{"v":52,"d":"52.00"},199.14,{"v":52,"d":"52.00"},199.14,"http://selleckchem.com/products/Pyridostigmine-Bromide(Mestinon).html","C9H13BrN2O2","Bromide","N/A","[Br-].CN(C)C(=O)OC1=C[N+](=CC=C1)C",-1.014,2,0,2]
["S1609","Methimazole","g10","L3800-04","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;BP2019;IP2010","N/A","Others","Others","Methimazole (Tapazole, Thiamazole) is an antithyroid medicine.",114.17,"60-56-0",{"v":23,"d":"23.00"},201.45,{"v":23,"d":"23.00"},201.45,"http://selleckchem.com/products/Methimazole(Tapazole).html","C4H6N2S","free base","Tapazole, Thiamazole","CN1C=CNC1=S",0.414,0,1,0]
["S1610","Metolazone","h10","L3800-04","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Phase 4","Others","Others","Metolazone (SR 720-22) is a diuretic that primarily used to treat congestive heart failure and high blood pressure.",365.83,"17560-51-9",{"v":73,"d":"73.00"},199.55,"<1","N/A","http://selleckchem.com/products/Metolazone(Zaroxolyn).html","C16H16ClN3O3S","free base","SR 720-22","CC1NC2=CC(=C(C=C2C(=O)N1C3=CC=CC=C3C)[S](N)(=O)=O)Cl",2.463,3,2,2]
["S1611","Cefoperazone","a11","L3800-04","in 10mM DMSO","FDA,DMF,CFDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 4","Antibiotics","Microbiology","Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM.",645.67,"62893-19-0",{"v":100,"d":"100.00"},154.88,"<1","N/A","http://selleckchem.com/products/cefoperazone-cefobid.html","C25H27N9O8S2","free base","N/A","CCN1CCN(C(=O)NC(C(=O)NC2C3SCC(=C(N3C2=O)C(O)=O)CSC4=NN=N[N]4C)C5=CC=C(O)C=C5)C(=O)C1=O",-0.792,9,3,9]
["S1613","Silodosin","b11","L3800-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Silodosin (KAD 3213, KMD 3213) is a highly selective α1A-adrenoceptor antagonist, used in treatment of benign prostatic hyperplasia.",495.53,"160970-54-7",{"v":99,"d":"99.00"},199.79,"<1","N/A","http://selleckchem.com/products/Silodosin(Rapaflo).html","C25H32F3N3O4","free base","KAD 3213, KMD 3213","CC(CC1=CC2=C(N(CCCO)CC2)C(=C1)C(N)=O)NCCOC3=CC=CC=C3OCC(F)(F)F",3.451,3,3,14]
["S1614","Riluzole (PK 26124)","c11","L3800-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","GluR,Sodium Channel","Transmembrane Transporters","Riluzole (PK 26124, RP-54274) is a glutamate release inhibitor with neuroprotective, anticonvulsant, anxiolytic and anesthetic qualities.",{"v":234.2,"d":"234.20"},"1744-22-5",{"v":46,"d":"46.00"},196.41,"<1","N/A","http://selleckchem.com/products/Riluzole(Rilutek).html","C8H5F3N2OS","free base","RP-54274, PK 26124","NC1=NC2=C(S1)C=C(OC(F)(F)F)C=C2",3.828,2,1,2]
["S1618","Sulfameter","d11","L3800-04","in 10mM DMSO","FDA","N/A","N/A","Bacterial","Immunology & Inflammation","Sulfameter  is a long-acting sulfonamide antibacterial.",{"v":280.3,"d":"280.30"},"651-06-9",{"v":56,"d":"56.00"},199.79,"<1","N/A","http://selleckchem.com/products/Sulfameter(Bayrena).html","C11H12N4O3S","free base","N/A","COC1=CN=C(N[S](=O)(=O)C2=CC=C(N)C=C2)N=C1",0.297,5,2,4]
["S1619","Prilocaine","e11","L3800-04","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;EP9.4;BP2019;Martindale:The Extra Pharmacopoeia","Marketed","Sodium Channel","Transmembrane Transporters","Prilocaine (NSC 40027) is a local anesthetic of the amino amide type. It acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation.",220.31,"721-50-6",{"v":44,"d":"44.00"},199.72,"<1","N/A","http://selleckchem.com/products/Prilocaine.html","C13H20N2O","free base","NSC 40027","CCCNC(C)C(=O)NC1=C(C)C=CC=C1",2.263,1,2,5]
["S1620","Darunavir Ethanolate","f11","L3800-04","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","Martindale:The Extra Pharmacopoeia","Marketed","COVID-19,HIV Protease","Proteases","Darunavir Ethanolate (TMC-114, UIC 94017) is a nonpeptidic HIV protease inhibitor, used to treat HIV infection.",593.73,"635728-49-3",{"v":100,"d":"100.00"},168.43,"<1","N/A","http://selleckchem.com/products/Darunavir-Ethanolate(Prezista).html","C27H37N3O7S.C2H5OH","Ethanolate","TMC-114, UIC 94017","CCO.CC(C)CN(CC(O)C(CC1=CC=CC=C1)NC(=O)OC2COC3OCCC23)[S](=O)(=O)C4=CC=C(N)C=C4",2.622,6,4,12]
["S1622","Prednisone (NSC-10023)","g11","L3800-04","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;EP9.3;BP2019;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Glucocorticoid Receptor,Immunology & Inflammation related","Endocrinology & Hormones","Prednisone (NSC-10023, Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.",358.43,"53-03-2",{"v":71,"d":"71.00"},198.09,"<1","N/A","http://selleckchem.com/products/Prednisone.html","C21H26O5","free base","Adasone,NSC-10023","CC12CC(=O)C3C(CCC4=CC(=O)C=CC34C)C1CCC2(O)C(=O)CO",1.217,3,1,2]
["S1625","Ethinyl Estradiol","h11","L3800-04","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010","Preregistration","Estrogen/progestogen Receptor","Endocrinology & Hormones","Ethinyl Estradiol is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills.",{"v":296.4,"d":"296.40"},"57-63-6",{"v":59,"d":"59.00"},199.06,"<1","N/A","http://selleckchem.com/products/Ethinyl-Estradiol.html","C20H24O2","free base","N/A","CC12CCC3C(CCC4=CC(=CC=C34)O)C1CCC2(O)C#C",4.886,0,1,0]
["S1626","Naproxen Sodium","a2","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 2","COX","Neuronal Signaling","Naproxen Sodium (RS-3650) is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively.",252.24,"26159-34-2",{"v":3,"d":"3.00"},11.89,{"v":50,"d":"50.00"},198.22,"http://selleckchem.com/products/Naproxen-Sodium(Aleve).html","C14H13NaO3","Sodium Salt","RS-3650","[Na+].COC1=CC=C2C=C(C=CC2=C1)C(C)C([O-])=O",1.375,1,0,3]
["S1627","Nitazoxanide (NSC 697855)","b2","L3800-05","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,Influenza Virus,mTOR,Serotonin Transporter","Microbiology","Nitazoxanide (NTZ, NSC 697855) is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent(IC50 for canine influenza virus ranges from 0.17 to 0.21 μM). Nitazoxanide modulates autophagy and inhibits mTORC1 signaling.",307.28,"55981-09-4",{"v":62,"d":"62.00"},201.77,"<1","N/A","http://selleckchem.com/products/Nitazoxanide(Alinia).html","C12H9N3O5S","free base","NTZ, NSC 697855","CC(=O)OC1=C(C=CC=C1)C(=O)NC2=NC=C(S2)[N+]([O-])=O",1.398,4,1,5]
["S1628","Triamcinolone Acetonide","c2","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP41-NF36;BP2018;EP9.2;IP2010;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Glucocorticoid Receptor","Metabolism","Triamcinolone acetonide is a synthetic glucocorticoid, used in the symptomatic treatment of inflammation.",{"v":434.5,"d":"434.50"},"76-25-5",{"v":87,"d":"87.00"},200.23,"<1","N/A","http://selleckchem.com/products/Triamcinolone-Acetonide.html","C24H31FO6","free base","N/A","CC1(C)OC2CC3C4CCC5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(O1)C(=O)CO",1.157,4,2,2]
["S1629","Orlistat (Ro 18-0647)","d2","L3800-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Fatty Acid Synthase,Lipase","Metabolism","Orlistat (Ro 18-0647, Tetrahydrolipstatin) is a general lipase inhibitor with IC50 of 122 ng/ml for PL from human duodenal juice. Orlistat treatment reduces proliferation, induces apoptosis and arrests cell cycle.",495.73,"96829-58-2",{"v":99,"d":"99.00"},199.71,"<1","N/A","http://selleckchem.com/products/Orlistat(Alli).html","C29H53NO5","free base","Tetrahydrolipstatin,Ro 18-0647","CCCCCCCCCCCC(CC1OC(=O)C1CCCCCC)OC(=O)C(CC(C)C)NC=O",8.333,5,1,23]
["S1630","Allopurinol","e2","L3800-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","ROS","Immunology & Inflammation","Allopurinol is a purine analog inhibitor of the enzyme xanthine oxidase, used to treat gout or kidney stones, and to decrease levels of uric acid.",136.11,"315-30-0",{"v":27,"d":"27.00"},198.37,{"v":4,"d":"4.00"},29.39,"http://selleckchem.com/products/Allopurinol(Zyloprim).html","C5H4N4O","Free Base","N/A","O=C1N=CN=C2NNC=C12",-2.125,3,2,0]
["S1631","Allopurinol Sodium","f2","L3800-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","ROS","Immunology & Inflammation","Allopurinol Sodium  is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.",{"v":159.1,"d":"159.10"},"17795-21-0",{"v":32,"d":"32.00"},201.13,{"v":32,"d":"32.00"},201.13,"http://selleckchem.com/products/Allopurinol-Sodium(Aloprim).html","C5H4N4NaO","Sodium Salt","N/A","[Na+].O=C1NC=NC2=C1C=N[NH]2",-0.681,3,2,0]
["S1633","Zafirlukast (ICI-204219)","g2","L3800-05","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia","Marketed","LTR","Immunology & Inflammation","Zafirlukast (ICI-204219) is an oral leukotriene receptor antagonist (LTRA), used to prevent asthma symptoms.",575.68,"107753-78-6",{"v":100,"d":"100.00"},173.71,"<1","N/A","http://selleckchem.com/products/Zafirlukast(Accolate).html","C31H33N3O6S","free base","ICI-204219","COC1=CC(=CC=C1CC2=C[N](C)C3=C2C=C(NC(=O)OC4CCCC4)C=C3)C(=O)N[S](=O)(=O)C5=CC=CC=C5C",6.299,6,2,9]
["S1635","Erythromycin","h2","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP38-NF33;BP2013;JP16;IP2010;Martindale:The Extra Pharmacopoeia","Registered","Antibiotics,Antibiotics for Mammalian Cell Culture","Microbiology","Erythromycin (E-Mycin) is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin (IC50=1.5 μg/ml).",733.93,"114-07-8",{"v":147,"d":"147.00"},200.29,{"v":3,"d":"3.00"},4.09,"http://selleckchem.com/products/Erythromycin(E-Mycin).html","C37H67NO13","Free Base","E-Mycin","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)C(=O)C(C)C(O)C1(C)O",1.792,8,3,7]
["S1636","Amphotericin B","a3","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;KP Ⅹ ;BP2015;EP9.2;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia;","Phase 2","Antibiotics,Antibiotics for Mammalian Cell Culture","Microbiology","Amphotericin B (AMB, NSC 527017) is an amphipathic polyene antibiotic which permeabilizes ergosterol-containing membranes.",924.08,"1397-89-3",{"v":22,"d":"22.00"},23.81,"<1","N/A","http://selleckchem.com/products/Amphotericin-B(Abelcet).html","C47H73NO17","free base","NSC 527017","CC1OC(OC/2CC3OC(O)(CC(O)CC(O)C(O)CCC(O)CC(O)CC(=O)OC(C)C(C)C(O)C(C)\\C=C\\C=C\\C=C\\C=C\\C=C\\C=C\\C=C2)CC(O)C3C(O)=O)C(O)C(N)C1O",-2.617,6,10,3]
["S1638","Ibuprofen (NSC 256857)","b3","L3800-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.6;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","COX","Neuronal Signaling","Ibuprofen (NSC 256857, Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively.",206.28,"15687-27-1",{"v":41,"d":"41.00"},198.76,"<1","N/A","http://selleckchem.com/products/Ibuprofen(Advil).html","C13H18O2","free base","Dolgesic,NSC 256857","CC(C)CC1=CC=C(C=C1)C(C)C(O)=O",3.607,1,0,4]
["S1639","Amprenavir (VX-478)","c3","L3800-05","in 10mM DMSO","FDA,DMF,EMA","Martindale:The Extra Pharmacopoeia","Marketed","HIV Protease","Proteases","Amprenavir (VX-478, 141W94, KVX-478) is a potent PXR-selective agonist, and an HIV protease inhibitor, used to treat HIV.",505.63,"161814-49-9",{"v":16,"d":"16.00"},31.64,"<1","N/A","http://selleckchem.com/products/Amprenavir-(Agenerase).html","C25H35N3O6S","free base","141W94, VX-478, KVX-478","CC(C)CN(CC(O)C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)[S](=O)(=O)C3=CC=C(N)C=C3",2.429,5,3,12]
["S1640","Albendazole (SKF-62979)","d3","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.6;KP Ⅹ;BP2018;Ph.Int_6th;Martindale:The Extra Pharmacopoeia","Marketed","ADC Cytotoxin,Microtubule Associated","Cytoskeletal Signaling","Albendazole (SKF-62979) is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.",265.33,"54965-21-8",{"v":17,"d":"17.00"},64.07,"<1","N/A","http://selleckchem.com/products/Albendazole(Albenza).html","C12H15N3O2S","free base","SKF-62979","CCCSC1=CC=C2N=C(NC(=O)OC)[NH]C2=C1",3.065,3,2,5]
["S1641","Chlorothiazide","e3","L3800-05","in 10mM DMSO","FDA,DMF,NDC","USP39-NF34;BP2015;IP2010;Martindale:The Extra Pharmacopoeia","Phase 4","Others","Others","Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM)",295.72,"58-94-6",{"v":59,"d":"59.00"},199.51,"<1","N/A","http://selleckchem.com/products/Chlorothiazide(Diuril).html","C7H6ClN3O4S2","free base","N/A","N[S](=O)(=O)C1=C(Cl)C=C2N=CN[S](=O)(=O)C2=C1",-0.177,5,2,1]
["S1643","Ursodiol","f3","L3800-05","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","Marketed","FXR","GPCR & G Protein","Ursodiol (Ursodeoxycholic acid, UDCA) reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones. (IC50=0.22 μM)",392.57,"128-13-2",{"v":79,"d":"79.00"},201.24,"<1","N/A","http://selleckchem.com/products/Ursodiol(Actigal).html","C24H40O4","free base","Ursodeoxycholic acid, UDCA","CC(CCC(O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C",4.014,1,2,4]
["S1644","Nitrofural","g3","L3800-05","in 10mM DMSO","CFDA","EP9.2","N/A","Anti-infection","Microbiology","Nitrofural (Nitrofurazone) is a topical anti-infective agent with an IC50 of 22.83 ± 1.2 μM. (Rat LD50 = 590 mg/kg)",198.14,"59-87-0",{"v":40,"d":"40.00"},201.88,"<1","N/A","http://selleckchem.com/products/Nitrofurazone(ACTIN-N).html","C6H6N4O4","free base","Nitrofurazone","NC(=O)N/N=C/C1=CC=C(O1)[N+]([O-])=O",0.223,3,2,3]
["S1645","Ketoprofen","h3","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 2","COX","Neuronal Signaling","Ketoprofen (RP-19583) is a dual COX1/2 inhibitor, used as a nonsteroidal anti-inflammatory drug to treat arthritis-related inflammatory pains.",254.28,"22071-15-4",{"v":51,"d":"51.00"},200.57,"<1","N/A","http://selleckchem.com/products/Ketoprofen(Actron).html","C16H14O3","free base","RP-19583","CC(C(O)=O)C1=CC(=CC=C1)C(=O)C2=CC=CC=C2",3.361,2,0,4]
["S1646","Ketorolac","a4","L3800-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;KP Ⅹ;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","COX","Neuronal Signaling","Ketorolac is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively.",255.27,"74103-06-3",{"v":75,"d":"75.00"},293.81,"<1","N/A","http://selleckchem.com/products/Ketorolac-Tromethamine(Toradol).html","C15H13N1O3","free base","N/A","OC(=O)C1CC[N]2C1=CC=C2C(=O)C3=CC=CC=C3",2.832,2,0,3]
["S1647","Adenosine","b4","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Adenosine Receptor,Nucleoside Analog/Antimetabolite","GPCR & G Protein","Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond.",267.24,"58-61-7",{"v":12,"d":"12.00"},{"v":44.9,"d":"44.90"},"<1","N/A","http://selleckchem.com/products/Adenosine(Adenocard).html","C10H13N5O4","free base","N/A","NC1=NC=NC2=C1N=C[N]2C3OC(CO)C(O)C3O",-1.881,4,4,2]
["S1649","Zolmitriptan","c4","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37 ;EP9.5;Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor","Neuronal Signaling","Zolmitriptan(BW-311C90) is a novel and highly selective 5-HT(1B/1D) receptor agonist, used in the treatment of acute migraines.",287.36,"139264-17-8",{"v":58,"d":"58.00"},201.84,"<1","N/A","http://selleckchem.com/products/Zolmitriptan(Zomig).html","C16H21N3O2","free base","BW-311C90","CN(C)CCC1=C[NH]C2=C1C=C(CC3COC(=O)N3)C=C2",2.457,2,2,5]
["S1651","Telbivudine","d4","L3800-05","in 10mM DMSO","FDA,DMF,EMA,CFDA","Martindale:The Extra Pharmacopoeia","Marketed","Reverse Transcriptase","Microbiology","Telbivudine(NV 02B) is a potent, and selective HBV reverse transcriptase inhibitor, used to treat HBV infection.",242.23,"3424-98-4",{"v":48,"d":"48.00"},198.16,{"v":48,"d":"48.00"},198.16,"http://selleckchem.com/products/Telbivudine(Sebivo).html","C10H14N2O5","free base","NV 02B","CC1=CN(C2CC(O)C(CO)O2)C(=O)NC1=O",-1.238,3,3,2]
["S1652","Monobenzone","e4","L3800-05","in 10mM DMSO","FDA,DMF","USP42-NF37;Martindale:The Extra Pharmacopoeia","N/A","Tyrosinase","Proteases","Monobenzone(Benoquin) is a compound used as a topical agent for medical depigmentation. It can specifically block tyrosinase.",200.23,"103-16-2",{"v":40,"d":"40.00"},199.77,"<1","N/A","http://selleckchem.com/products/Monobenzone(Benoquin).html","C13H12O2","free base","Benoquin","OC1=CC=C(OCC2=CC=CC=C2)C=C1",3.155,1,1,3]
["S1653","Tretinoin (NSC 122758)","f4","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.2;BP2017;Martindale:The Extra Pharmacopoeia","Marketed","Retinoid Receptor","Metabolism","Tretinoin (Retinoic acid, All-trans Retinoic Acid, ATRA, Vitamin A acid, Vesanoid, Airol, Renova, Atralin, Retin-A, Avita, Stieva-A,NSC 122758), which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.",{"v":300.4,"d":"300.40"},"302-79-4",{"v":60,"d":"60.00"},199.73,"<1","N/A","http://selleckchem.com/products/Tretinoin(Aberela).html","C20H28O2","free base","Retinoic acid, All-trans Retinoic Acid, ATRA, Vitamin A acid, Vesanoid, Airol, Renova, Atralin, Retin-A, Avita, Stieva-A,NSC 122758","CC1=C(\\C=C\\C(C)=C\\C=C\\C(C)=C\\C(O)=O)C(C)(C)CCC1",5.551,1,0,5]
["S1654","Phenylbutazone","g4","L3800-05","in 10mM DMSO","FDA,DMF,CFDA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","N/A","Immunology & Inflammation related","Immunology & Inflammation","Phenylbutazone (Butazolidine) is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis.",308.37,"50-33-9",{"v":62,"d":"62.00"},201.06,"<1","N/A","http://selleckchem.com/products/Phenylbutazone(Butazolidin).html","C19H20N2O2","free base","Butazolidine","CCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3",3.954,2,0,5]
["S1655","Ezetimibe (SCH-58235)","h4","L3800-05","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","LDL","Metabolism","Ezetimibe (SCH-58235) is a potent, selective, cholesterol absorption inhibitor, used to lower cholesterol.",{"v":409.4,"d":"409.40"},"163222-33-1",{"v":81,"d":"81.00"},197.85,"<1","N/A","http://selleckchem.com/products/Ezetimibe(Zetia).html","C24H21F2NO3","free base","SCH-58235","OC(CCC1C(N(C1=O)C2=CC=C(F)C=C2)C3=CC=C(O)C=C3)C4=CC=C(F)C=C4",4.633,1,2,6]
["S1657","Enalaprilat Dihydrate","a5","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Phase 3","RAAS","Endocrinology & Hormones","Enalaprilat (MK-422) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.",{"v":348.4,"d":"348.40"},"84680-54-6",{"v":70,"d":"70.00"},200.92,"<1","N/A","http://selleckchem.com/products/Enalaprilat.html","C18H24N2O5.2H2O","Dihydrate","MK-422 Dihydrate","O.O.CC(NC(CCC1=CC=CC=C1)C(O)=O)C(=O)N2CCCC2C(O)=O",{"v":-1.53,"d":"-1.530"},3,1,8]
["S1658","Dofetilide","b5","L3800-05","in 10mM DMSO","FDA,DMF,EMA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","Potassium Channel","Transmembrane Transporters","Dofetilide (UK-68798) is a selective potassium channel ((hERG)) blocker, used as a Class III antiarrhythmic drug.",441.56,"115256-11-6",{"v":88,"d":"88.00"},199.29,"<1","N/A","http://selleckchem.com/products/Dofetilide(Tikosyn).html","C19H27N3O5S2","free base","UK-68798","CN(CCOC1=CC=C(N[S](C)(=O)=O)C=C1)CCC2=CC=C(N[S](C)(=O)=O)C=C2",1.679,5,2,11]
["S1662","Isradipine","c5","L3800-05","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Martindale:The Extra Pharmacopoeia","Phase 3","Calcium Channel","Transmembrane Transporters","Isradipine (PN 200-110) is a potent and selective L-type voltage-gated calcium channel blocker, used to treat high blood pressure.",371.39,"75695-93-1",{"v":74,"d":"74.00"},199.25,"<1","N/A","http://selleckchem.com/products/Isradipine(Dynacirc).html","C19H21N3O5","free base","PN 200-110","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC3=NON=C23)C(=O)OC(C)C)C",2.168,7,1,6]
["S1665","Estrone","d5","L3800-05","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","N/A","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estrone is an estrogenic hormone.",270.37,"53-16-7",{"v":54,"d":"54.00"},199.73,"<1","N/A","http://selleckchem.com/products/Estrone.html","C18H22O2","free base","N/A","CC12CCC3C(CCC4=CC(=CC=C34)O)C1CCC2=O",3.938,1,1,0]
["S1666","Flucytosine","e5","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;Ph.Int_6th;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 1/2","Fungal","Microbiology","Flucytosine (5-Fluorocytosine, 5-FC, NSC 103805, Ro 2-9915) is an antifungal drug with IC50 of 0.93 μM in C. albicans.",129.09,"2022-85-7",{"v":8,"d":"8.00"},61.97,{"v":5,"d":"5.00"},38.73,"http://selleckchem.com/products/Flucytosine(Ancobon).html","C4H4FN3O","free base","5-Fluorocytosine, 5-FC, NSC 103805, Ro 2-9915","NC1=NC(=O)NC=C1F",-1.048,2,2,0]
["S1667","Trichlormethiazide","f5","L3800-05","in 10mM DMSO","FDA,DMF,PMDA","USP42-NF37;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Others","Others","Trichlormethiazide is a diuretic with properties similar to those of hydrochlorothiazide.",380.66,"133-67-5",{"v":54,"d":"54.00"},141.86,"<1","N/A","http://selleckchem.com/products/Trichlormethiazide(Achletin).html","C8H8Cl3N3O4S2","free base","N/A","N[S](=O)(=O)C1=C(Cl)C=C2NC(N[S](=O)(=O)C2=C1)C(Cl)Cl",1.046,4,3,2]
["S1669","Loteprednol etabonate","g5","L3800-05","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","Marketed","Glucocorticoid Receptor","Endocrinology & Hormones","Loteprednol etabonate is a potent glucocorticoid receptor agonist, used in treatment of inflammation of the eye due to allergies.",466.95,"82034-46-6",{"v":93,"d":"93.00"},199.16,"<1","N/A","http://selleckchem.com/products/Loteprednol-etabonate.html","C24H31ClO7","free base","N/A","CCOC(=O)OC1(CCC2C3CCC4=CC(=O)C=CC4(C)C3C(O)CC12C)C(=O)OCCl",3.865,6,1,7]
["S1673","Aminophylline","h5","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","Phase 3","PDE","Metabolism","Aminophylline (Phyllocontin) is a competitive nonselective phosphodiesterase inhibitor with an IC50 of 0.12 mM and also a nonselective adenosine receptor antagonist.",420.43,"317-34-0",{"v":53,"d":"53.00"},126.06,{"v":84,"d":"84.00"},{"v":199.8,"d":"199.80"},"http://selleckchem.com/products/Aminophylline(Truphylline).html","C16H24N10O4","Ethylenediamine","Phyllocontin","CN1C(=O)N(C)C2=C([NH]C=N2)C1=O.CN3C(=O)N(C)C4=C([NH]C=N4)C3=O.NCCN",-2.089,6,4,1]
["S1675","Lubiprostone","a6","L3800-05","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia","Marketed","Chloride Channel","Transmembrane Transporters","Lubiprostone (RU 0211,SPI-0211) is an activator of ClC-2 chloride channels, used in the management of idiopathic chronic constipation.",390.46,"136790-76-6",{"v":78,"d":"78.00"},199.76,"<1","N/A","http://selleckchem.com/products/Lubiprostone(Amitiza).html","C20H32F2O5","Free Base","RU 0211,SPI-0211","CCCCC(F)(F)C(=O)CCC1C(O)CC(=O)C1CCCCCCC(O)=O",3.831,3,1,14]
["S1676","Amorolfine HCl","b6","L3800-05","in 10mM DMSO","DMF,CFDA,PMDA,HMA","EP9.7;BP2019;Martindale:The Extra Pharmacopoeia","Phase 4","Fungal","Microbiology","Amorolfine HCl(Ro 14-4767 HCl) is an antifungal reagent.",353.97,"78613-38-4",{"v":28,"d":"28.00"},{"v":79.1,"d":"79.10"},{"v":9,"d":"9.00"},25.43,"http://selleckchem.com/products/Amorolfine-Hydrochloride.html","C21H35NO.HCl","Hydrochloride","Ro 14-4767 HCl","Cl.CCC(C)(C)C1=CC=C(CC(C)CN2CC(C)OC(C)C2)C=C1",5.681,1,0,6]
["S1677","Chloramphenicol","c6","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","JP17;BP2017;Ph.Int_5th;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics for Plant Cell Culture,Bacterial,Selection Antibiotics for Transfected Cell","Microbiology","Chloramphenicol (Chloromycetin) is a bacteriostatic by inhibiting protein synthesis.",323.13,"56-75-7",{"v":65,"d":"65.00"},201.16,"<1","N/A","http://selleckchem.com/products/Chloramphenicol(Chloromycetin).html","C11H12Cl2N2O5","free base","Chloromycetin","OCC(NC(=O)C(Cl)Cl)C(O)C1=CC=C(C=C1)[N+]([O-])=O",1.025,1,3,6]
["S1679","Flurbiprofen","d6","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Immunology & Inflammation related","Immunology & Inflammation","Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs).",244.26,"5104-49-4",{"v":49,"d":"49.00"},200.61,"<1","N/A","http://selleckchem.com/products/Flurbiprofen(Ansaid).html","C15H13FO2","free base","N/A","CC(C(O)=O)C1=CC(=C(C=C1)C2=CC=CC=C2)F",{"v":3.68,"d":"3.680"},1,0,3]
["S1680","Disulfiram (NSC 190940)","e6","L3800-05","in 10mM DMSO","FDA,DMF,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Apoptosis related,COVID-19,Dehydrogenase,Pyroptosis","Metabolism","Disulfiram (NSC 190940, Tetraethylthiuram disulfide, TETD) is a specific inhibitor of aldehyde-dehydrogenase (ALDH) with IC50 of 0.15 μM and 1.45 μM for hALDH1 and hALDH2, respectively. Disulfiram is used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram induces apoptosis. Disulfiram is also an inhibitor of pore formation by gasdermin D (GSDMD).",296.54,"97-77-8",{"v":59,"d":"59.00"},198.96,"<1","N/A","http://selleckchem.com/products/Disulfiram(Antabuse).html","C10H20N2S4","free base","NSC 190940, Tetraethylthiuram disulfide, TETD","CCN(CC)C(=S)SSC(=S)N(CC)CC",{"v":5.6,"d":"5.600"},0,0,9]
["S1681","Mesalamine (5-ASA)","f6","L3800-05","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","Marketed","Immunology & Inflammation related,IκB/IKK","NF-κB","Mesalamine (5-Aminosalicylic acid, 5-ASA, Mesalazine, Apriso, Asacol, Pentasa, Canasa) is a specific inhibitor of TNFα-induced IKK activity, used to treat inflammatory bowel disease.",153.14,"89-57-6",{"v":31,"d":"31.00"},202.43,"<1","N/A","http://selleckchem.com/products/Mesalamine(Lialda).html","C7H7NO3","free base","5-Aminosalicylic acid, 5-ASA, Mesalazine, Apriso, Asacol, Pentasa, Canasa","NC1=CC=C(O)C(=C1)C(O)=O",0.471,1,2,1]
["S1683","Ipratropium Bromide","g6","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.6;JP17;Martindale:The Extra Pharmacopoeia","Marketed","AChR","Neuronal Signaling","Ipratropium Bromide is an antagonist of M3 type muscarinic acetylcholine receptors, used for the treatment of chronic obstructive pulmonary disease (COPD).",412.37,"22254-24-6",{"v":83,"d":"83.00"},201.28,{"v":83,"d":"83.00"},201.28,"http://selleckchem.com/products/Ipratropium-bromide.html","C20H30BrNO3","Bromide","N/A","[Br-].CC(C)[N+]1(C)C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",-1.326,2,1,6]
["S1685","Sulfanilamide","h6","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Bacterial","Microbiology","Sulfanilamide (Sulphanilamide) is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.",{"v":172.2,"d":"172.20"},"63-74-1",{"v":34,"d":"34.00"},197.44,"<1","N/A","http://selleckchem.com/products/Sulfanilamide.html","C6H8N2O2S","free base","N/A","NC1=CC=C(C=C1)[S](N)(=O)=O",-0.212,2,2,1]
["S1688","Betamethasone Dipropionate","a7","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.3;KP Ⅹ;BP2019;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Glucocorticoid Receptor","Endocrinology & Hormones","Betamethasone Dipropionate (SCH 11460) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.",504.59,"5593-20-4",{"v":100,"d":"100.00"},198.18,"<1","N/A","http://selleckchem.com/products/Betamethasone-Dipropionate(Diprolene).html","C28H37FO7","Free Base","SCH 11460","CCC(=O)OCC(=O)C1(OC(=O)CC)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C",{"v":3.8,"d":"3.800"},6,1,8]
["S1689","Meprednisone","b7","L3800-05","in 10mM DMSO","FDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","N/A","Glucocorticoid Receptor","Endocrinology & Hormones","Meprednisone (NSC 527579, SCH 4358) is a glucocorticoid and a methylated derivative of prednisone.",372.46,"1247-42-3",{"v":75,"d":"75.00"},201.37,"<1","N/A","http://selleckchem.com/products/Betapar(Meprednisone).html","C22H28O5","free base","NSC 527579, SCH 4358","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3C(=O)CC2(C)C1(O)C(=O)CO",1.536,3,1,2]
["S1690","Betamethasone Valerate","c7","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37 ;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Glucocorticoid Receptor","Endocrinology & Hormones","Betamethasone Valerate is a moderately potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.",476.58,"2152-44-5",{"v":95,"d":"95.00"},199.34,"<1","N/A","http://selleckchem.com/products/Betamethasone-valerate(Betnovate).html","C27H37FO6","free base","N/A","CCCCC(=O)OC1(C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)CO",3.666,4,2,7]
["S1691","Praziquantel","d7","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Phase 2","COVID-19,Parasite","Microbiology","Praziquantel is an anthelmintic effective against flatworms.",312.41,"55268-74-1",{"v":63,"d":"63.00"},201.66,"<1","N/A","http://selleckchem.com/products/Praziquantel(Biltricide).html","C19H24N2O2","free base","N/A","O=C1CN(CC2N1CCC3=CC=CC=C23)C(=O)C4CCCCC4",2.477,2,0,1]
["S1692","Busulfan (NSC-750)","e7","L3800-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,DNA alkylator","DNA Damage/DNA Repair","Busulfan (NSC-750) is a cell cycle non-specific alkylating antineoplastic agent. Busulfan induces apoptosis.",{"v":246.3,"d":"246.30"},"55-98-1",{"v":49,"d":"49.00"},198.94,"<1","N/A","http://selleckchem.com/products/Busulfan(Busulfex).html","C6H14O6S2","free base","NSC-750","C[S](=O)(=O)OCCCCO[S](C)(=O)=O",-0.289,2,0,7]
["S1693","Carbamazepine","f7","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,Sodium Channel","Transmembrane Transporters","Carbamazepine (Carbatrol, NSC 169864) is a sodium channel blocker with IC50 of 131 μM in rat brain synaptosomes.",236.27,"298-46-4",{"v":47,"d":"47.00"},198.92,"<1","N/A","http://selleckchem.com/products/Carbamazepine(Carbatrol).html","C15H12N2O","free base","NSC 169864","NC(=O)N1C2=C(C=CC=C2)C=CC3=C1C=CC=C3",2.679,1,1,0]
["S1696","Hydrocortisone (NSC 10483)","g7","L3800-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP35-NF30;BP2010;JP15;Martindale:The Extra Pharmacopoeia","Marketed","Glucocorticoid Receptor","Endocrinology & Hormones","Hydrocortisone (NSC 10483, Cortisol) is a steroid hormone or glucocorticoid produced by the adrenal gland.",362.46,"50-23-7",{"v":73,"d":"73.00"},{"v":201.4,"d":"201.40"},"<1","N/A","http://selleckchem.com/products/Hydrocortisone.html","C21H30O5","free base","Cortisol","CC12CCC(=O)C=C1CCC3C4CCC(O)(C(=O)CO)C4(C)CC(O)C23",1.283,2,2,2]
["S1701","Desonide","h7","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;USP38-NF33;Martindale:The Extra Pharmacopoeia","Marketed","Glucocorticoid Receptor","Endocrinology & Hormones","Desonide is a low potency topical corticosteroid.",416.51,"638-94-8",{"v":83,"d":"83.00"},199.27,"<1","N/A","http://selleckchem.com/products/Desonide.html","C24H32O6","free base","N/A","CC1(C)OC2CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC3(C)C2(O1)C(=O)CO",1.028,4,2,2]
["S1702","Didanosine","a8","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Reverse Transcriptase","Microbiology","Didanosine is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.",236.23,"69655-05-6",{"v":47,"d":"47.00"},198.96,"<1","N/A","http://selleckchem.com/products/Didanosine(Videx).html","C10H12N4O3","free base","N/A","OCC1CCC(O1)[N]2C=NC3=C2N=CNC3=O",-0.844,4,2,2]
["S1703","Divalproex Sodium","b8","L3800-05","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;IP2010","Marketed","HDAC","Epigenetics","Divalproex Sodium, consisting of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form, is a HDAC inhibitor, used in the treatment for epilepsy.",310.41,"76584-70-8",{"v":62,"d":"62.00"},199.74,{"v":62,"d":"62.00"},199.74,"http://selleckchem.com/products/Divalproex-sodium.html","C8H16O2.C8H15O2.Na","Sodium Salt","N/A","[Na+].CCCC(CCC)C(O)=O.CCCC(CCC)C([O-])=O",4.025,1,0,10]
["S1704","Emtricitabine (BW 1592)","c8","L3800-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","HBV,HIV,Reverse Transcriptase","Microbiology","Emtricitabine (BW1592, FTC) is a new nucleoside agent that has activity against both human immunodeficiency virus (HIV) and hepatitis B virus. It is a reverse transcriptase inhibitor. Intracellular half-life is 39 h.",247.25,"143491-57-0",{"v":49,"d":"49.00"},198.18,{"v":49,"d":"49.00"},198.18,"http://selleckchem.com/products/Emtricitabine.html","C8H10FN3O3S","free base","FTC, BW1592","NC1=NC(=O)N(C=C1F)C2CSC(CO)O2",{"v":-0.68,"d":"-0.680"},3,2,2]
["S1705","Progesterone (NSC 9704)","d8","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;KP Ⅹ; EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Progesterone (NSC 9704, NSC 64377, Pregn-4-ene-3,20-dione) is an endogenous steroid hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. A potent agonist of the nuclear progesterone receptor (nPR) with Kd of 1 nM; An agonist of the membrane progesterone receptors(mPRs); An antagonist of the σ1 receptor.",314.46,"57-83-0",{"v":22,"d":"22.00"},69.96,"<1","N/A","http://selleckchem.com/products/Progesterone(Prometrium).html","C21H30O2","free base","NSC 64377, Pregn-4-ene-3,20-dione,NSC 9704","CC(=O)C1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C",{"v":3.86,"d":"3.860"},2,0,1]
["S1706","Lamivudine (BCH-189)","e8","L3800-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","COVID-19,Reverse Transcriptase","Microbiology","Lamivudine (BCH-189, GR109714X) is a potent nucleoside analog reverse transcriptase inhibitor, used for treatment of chronic HBV and HIV/AIDS. It works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase.",229.26,"134678-17-4",{"v":46,"d":"46.00"},200.65,{"v":46,"d":"46.00"},200.65,"http://selleckchem.com/products/Lamivudine(Epivir).html","C8H11N3O3S","free base","GR109714X, BCH-189","NC1=NC(=O)N(C=C1)C2CSC(CO)O2",{"v":-0.59,"d":"-0.590"},3,2,2]
["S1709","Estradiol","f8","L3800-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP39-NF34;BP2015;JP16;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Estrogen/progestogen Receptor,Interleukins","Endocrinology & Hormones","Estradiol (17β-estradiol, β-Estradiol, E2, 17β-Oestradiol) is a human sex hormone and steroid, and the primary female sex hormone. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.",272.38,"50-28-2",{"v":54,"d":"54.00"},198.25,"<1","N/A","http://selleckchem.com/products/Estradiol.html","C18H24O2","free base","17β-estradiol, β-Estradiol, E2, 17β-Oestradiol","CC12CCC3C(CCC4=C3C=CC(=C4)O)C1CCC2O",3.838,0,2,0]
["S1712","Deferasirox (ICL-670)","g8","L3800-05","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","EP;Martindale:The Extra Pharmacopoeia","Marketed","Ferroptosis,P450 (e.g. CYP17)","Proteases","Deferasirox (ICL-670, CGP-72670) is an iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor. Deferasirox-induced iron depletion promotes BclxL downregulation and cell death.",373.36,"201530-41-8",{"v":74,"d":"74.00"},{"v":198.2,"d":"198.20"},"<1","N/A","http://selleckchem.com/products/Deferasirox(Exjade).html","C21H15N3O4","free base","CGP-72670, ICL-670","OC(=O)C1=CC=C(C=C1)[N]2N=C(N=C2C3=CC=CC=C3O)C4=CC=CC=C4O",4.063,3,2,4]
["S1713","Piroxicam","h8","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37 ;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","COX","Neuronal Signaling","Piroxicam (CP 16171) is a non-selective COX inhibitor, used in the treatment of rheumatoid and osteoarthritis.",331.35,"36322-90-4",{"v":66,"d":"66.00"},199.19,"<1","N/A","http://selleckchem.com/products/Piroxicam(Feldene).html","C15H13N3O4S","free base","CP 16171","CN1C(=C(O)C2=C(C=CC=C2)[S]1(=O)=O)C(=O)NC3=NC=CC=C3",0.501,4,2,2]
["S1714","Gemcitabine (LY-188011)","a9","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,DNA/RNA Synthesis,Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Gemcitabine (LY-188011, NSC 613327), a nucleic acid synthesis inhibitor, is a very potent and specific deoxycytidine analogue, used as chemotherapy. Gemcitabine induces a potent p53-dependent apoptosis.",{"v":263.2,"d":"263.20"},"95058-81-4",{"v":52,"d":"52.00"},197.57,{"v":52,"d":"52.00"},197.57,"http://selleckchem.com/products/Gemcitabine(Gemzar).html","C9H11F2N3O4","Free Base","LY-188011, NSC 613327","NC1=NC(=O)N(C=C1)C2OC(CO)C(O)C2(F)F",-1.394,3,3,2]
["S1715","Glipizide","b9","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;EP9.7;BP2019;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Potassium Channel","Transmembrane Transporters","Glipizide (CP-28720,K 4024) is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes.",445.54,"29094-61-9",{"v":89,"d":"89.00"},199.76,"<1","N/A","http://selleckchem.com/products/Glipizide(Glucotrol).html","C21H27N5O4S","free base","CP-28720,K 4024","CC1=NC=C(N=C1)C(=O)NCCC2=CC=C(C=C2)[S](=O)(=O)NC(=O)NC3CCCCC3",1.902,6,3,7]
["S1716","Glyburide (Glibenclamide)","c9","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37","Marketed","Potassium Channel","Transmembrane Transporters","Glyburide (Glibenclamide) is a known blocker of vascular ATP-sensitive K+ channels (KATP), used in the treatment of type 2 diabetes.",{"v":494,"d":"494.00"},"10238-21-8",{"v":99,"d":"99.00"},{"v":200.4,"d":"200.40"},"<1","N/A","http://selleckchem.com/products/Glyburide(Diabeta).html","C23H28ClN3O5S","free base","Glibenclamide","COC1=C(C=C(Cl)C=C1)C(=O)NCCC2=CC=C(C=C2)[S](=O)(=O)NC(=O)NC3CCCCC3",{"v":4.14,"d":"4.140"},5,3,8]
["S1717","Fomepizole","d9","L3800-05","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia","Marketed","Dehydrogenase","Metabolism","Fomepizole (4-methylpyrazole, Antizol, Antizol-Vet) is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.",{"v":82.1,"d":"82.10"},"7554-65-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/Fomepizole(Antizol).html","C4H6N2","free base","4-methylpyrazole, Antizol, Antizol-Vet","CC1=C[NH]N=C1",{"v":0.76,"d":"0.760"},1,1,0]
["S1718","Adefovir Dipivoxil (GS 0840)","e9","L3800-05","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia","N/A","Reverse Transcriptase","Microbiology","Adefovir Dipivoxil (GS 0840) is a reverse transcriptase inhibitor, used in the treatment of chronic hepatitis B virus (HBV).",501.47,"142340-99-6",{"v":100,"d":"100.00"},199.41,"<1","N/A","http://selleckchem.com/products/Adefovir-Dipivoxil(Preveon).html","C20H32N5O8P","free base","GS 0840","CC(C)(C)C(=O)OCO[P](=O)(COCC[N]1C=NC2=C1N=CN=C2N)OCOC(=O)C(C)(C)C",1.666,10,1,15]
["S1719","Zalcitabine","f9","L3800-05","in 10mM DMSO","FDA,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","N/A","Reverse Transcriptase","Microbiology","Zalcitabine (NSC 606170, Ro 24-2027/000) is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI).",211.22,"7481-89-2",{"v":7,"d":"7.00"},33.14,{"v":42,"d":"42.00"},198.84,"http://selleckchem.com/products/Zalcitabine.html","C9H13N3O3","free base","NSC 606170, Ro 24-2027/000","NC1=NC(=O)N(C=C1)C2CCC(CO)O2",-0.991,3,2,2]
["S1721","Azathioprine","g9","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;IP2010;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Rho","Cell Cycle","Azathioprine(BW 57-322) is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases.",277.26,"446-86-6",{"v":54,"d":"54.00"},194.76,"<1","N/A","http://selleckchem.com/products/Azathioprine(Azasan).html","C9H7N7O2S","free base","BW 57-322","C[N]1C=NC(=C1SC2=C3[NH]C=NC3=NC=N2)[N+]([O-])=O",1.071,4,1,3]
["S1723","Indomethacin (NSC-77541)","h9","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;KP Ⅹ;IP2010;CP2005","Marketed","COX","Neuronal Signaling","Indomethacin (NSC-77541, Indometacin) is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively, used to reduce fever, pain, stiffness, and swelling.",357.79,"53-86-1",{"v":72,"d":"72.00"},201.24,"<1","N/A","http://selleckchem.com/products/Indomethacin(Indocid).html","C19H16ClNO4","free base","Indometacin,NSC-77541","COC1=CC=C2[N](C(=C(CC(O)=O)C2=C1)C)C(=O)C3=CC=C(Cl)C=C3",4.235,3,0,4]
["S1725","Terbinafine","a10","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Fungal","Microbiology","Terbinafine (SF 86-327,TDT 067) is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.",291.43,"91161-71-6",{"v":58,"d":"58.00"},199.02,"<1","N/A","http://selleckchem.com/products/Terbinafine(Lamisil).html","C21H25N","Free Base","SF 86-327,TDT 067","CN(C\\C=C\\C#CC(C)(C)C)CC1=CC=CC2=CC=CC=C12",5.335,0,0,6]
["S1727","Levonorgestrel","b10","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Levonorgestrel (D-Norgestrel) is a female hormone that prevents ovulation.",312.45,"797-63-7",{"v":45,"d":"45.00"},144.02,"<1","N/A","http://selleckchem.com/products/Levonorgestrel(Levonelle).html","C21H28O2","free base","D-Norgestrel","CCC12CCC3C(CCC4=CC(=O)CCC34)C1CCC2(O)C#C",4.771,1,0,1]
["S1729","Gemfibrozil","c10","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2","Phase 2","PPAR","Metabolism","Gemfibrozil (CI-719) is an activator of peroxisome proliferator-activated receptor-alpha (PPARα), used for the treatment of hypercholesterolemia and hypertriglyceridemia.",250.33,"25812-30-0",{"v":50,"d":"50.00"},199.74,"<1","N/A","http://selleckchem.com/products/Gemfibrozil(Lopid).html","C15H22O3","free base","CI-719","CC1=CC(=C(C)C=C1)OCCCC(C)(C)C(O)=O",4.172,2,0,6]
["S1730","Indapamide","d10","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Indapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.",365.83,"26807-65-8",{"v":73,"d":"73.00"},199.55,"<1","N/A","http://selleckchem.com/products/Indapamide(Lozol).html","C16H16ClN3O3S","free base","N/A","CC1CC2=C(C=CC=C2)N1NC(=O)C3=CC=C(Cl)C(=C3)[S](N)(=O)=O",2.664,3,2,3]
["S1732","Mitotane","e10","L3800-05","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","Others","Others","Mitotane (NCI-C04933), is an antineoplastic medication used in the treatment of adrenocortical carcinoma.",320.04,"53-19-0",{"v":64,"d":"64.00"},199.98,"<1","N/A","http://selleckchem.com/products/Mitotane(Lysodren).html","C14H10Cl4","free base","NCI-C04933","ClC(Cl)C(C1=CC=C(Cl)C=C1)C2=C(Cl)C=CC=C2",5.745,0,0,3]
["S1733","Methylprednisolone (NSC-19987)","f10","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","ACE,Apoptosis related,Autophagy,Glucocorticoid Receptor,Immunology & Inflammation related,Interleukins","Endocrinology & Hormones","Methylprednisolone (NSC-19987,U 7532) is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.",374.47,"83-43-2",{"v":75,"d":"75.00"},200.28,"<1","N/A","http://selleckchem.com/products/Methylprednisolone.html","C22H30O5","free base","NSC-19987,U 7532","CC1CC2C3CCC(O)(C(=O)CO)C3(C)CC(O)C2C4(C)C=CC(=O)C=C14",1.512,2,2,2]
["S1734","Meloxicam","g10","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Martindale:The Extra Pharmacopoeia","Marketed","COX","Neuronal Signaling","Meloxicam is a selective COX inhibitor, used to relieve pain and fever effects.",{"v":351.4,"d":"351.40"},"71125-38-7",{"v":30,"d":"30.00"},85.37,"<1","N/A","http://selleckchem.com/products/Meloxicam(Mobic).html","C14H13N3O4S2","free base","N/A","CN1C(=C(O)C2=C(C=CC=C2)[S]1(=O)=O)C(=O)NC3=NC=C(C)S3",0.255,4,2,2]
["S1735","Mesna","h10","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Others","Others","Mesna, a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents.",164.18,"19767-45-4",{"v":33,"d":"33.00"},{"v":201,"d":"201.00"},{"v":7,"d":"7.00"},42.64,"http://selleckchem.com/products/Mesna(Uromitexan).html","C2H5NaO3S2","Sodium Salt","N/A","[Na+].[O-][S](=O)(=O)CCS",-2.227,0,0,2]
["S1736","Methocarbamol","a11","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;KP Ⅹ;Martindale:The Extra Pharmacopoeia","Phase 3","Carbonic Anhydrase","Metabolism","Methocarbamol (AHR 85) is a carbonic anhydrase inhibitor, used as a central muscle relaxant to treat skeletal muscle spasms.",241.24,"532-03-6",{"v":48,"d":"48.00"},198.97,{"v":2,"d":"2.00"},8.29,"http://selleckchem.com/products/Methocarbamol(Robaxin).html","C11H15NO5","free base","AHR 85","COC1=C(OCC(O)COC(N)=O)C=CC=C1",0.916,4,2,7]
["S1737","Prednisolone (NSC-9900)","b11","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","BP2013;JP16;IP2010;USP35-NF30;Martindale:The Extra Pharmacopoeia","Phase 3","Glucocorticoid Receptor,Immunology & Inflammation related","Endocrinology & Hormones","Prednisolone (NSC-9900) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.",360.44,"50-24-8",{"v":72,"d":"72.00"},199.76,"<1","N/A","http://selleckchem.com/products/Prednisolone(Hydroretrocortine).html","C21H28O5","Free Base","NSC-9900","CC12CC(O)C3C(CCC4=CC(=O)C=CC34C)C1CCC2(O)C(=O)CO",{"v":1.26,"d":"1.260"},2,2,2]
["S1738","Telmisartan","c11","L3800-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.7;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Angiotensin Receptor","GPCR & G Protein","Telmisartan (BIBR 277) is an angiotensin II receptor antagonist (ARB) used in the management of hypertension.",514.62,"144701-48-4",{"v":13,"d":"13.00"},25.26,"<1","N/A","http://selleckchem.com/products/Telmisartan(Micardis).html","C33H30N4O2","free base","BIBR 277","CCCC1=NC2=C(C=C(C=C2C)C3=NC4=C(C=CC=C4)[N]3C)[N]1CC5=CC=C(C=C5)C6=CC=CC=C6C(O)=O",7.799,3,0,7]
["S1739","Thiabendazole","d11","L3800-05","in 10mM DMSO","FDA,DMF","USP42-NF37;IP2010","N/A","P450 (e.g. CYP17)","Metabolism","Thiabendazole inhibits the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property, used as an anthelmintic and fungicide agent. It is a potent inhibitor of  cytochrome P450 1A2 (CYP1A2).",201.25,"148-79-8",{"v":40,"d":"40.00"},198.76,"<1","N/A","http://selleckchem.com/products/Thiabendazole.html","C10H7N3S","free base","N/A","[NH]1C2=C(C=CC=C2)N=C1C3=CSC=N3",2.154,2,1,1]
["S1740","Guaifenesin","e11","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.4;KP Ⅹ;BP2017;JP17;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Guaifenesin is an expectorant used to relieve chest congestion.",198.22,"93-14-1",{"v":40,"d":"40.00"},{"v":201.8,"d":"201.80"},{"v":25,"d":"25.00"},126.12,"http://selleckchem.com/products/Guaifenesin(Guaiphenesin).html","C10H14O4","free base","N/A","COC1=C(OCC(O)CO)C=CC=C1",0.747,2,2,5]
["S1741","Rifabutin (LM427)","f11","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Bacterial","Microbiology","Rifabutin (LM427, Ansamycin) is a semisynthetic ansamycin antibiotic, used in the treatment of Mycobacterium avium intracellulare (MAI) and tuberculosis.",{"v":847,"d":"847.00"},"72559-06-9",{"v":60,"d":"60.00"},70.84,"<1","N/A","http://selleckchem.com/products/Rifabutin(Mycobutin).html","C46H62N4O11","free base","LM427, Ansamycin","COC1\\C=C\\OC2(C)OC3=C(C2=O)C4=C(C(=C3C)O)C(=O)C(=C5NC6(CCN(CC6)CC(C)C)N=C45)NC(=O)/C(=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)C",3.931,9,5,5]
["S1742","Nevirapine (NSC 641530)","g11","L3800-05","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.3;BP2019;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Reverse Transcriptase","Microbiology","Nevirapine (NSC 641530,NVP) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.",{"v":266.3,"d":"266.30"},"129618-40-2",{"v":53,"d":"53.00"},199.02,"<1","N/A","http://selleckchem.com/products/Nevirapine(Viramune).html","C15H14N4O","free base","NSC 641530,NVP","CC1=CC=NC2=C1NC(=O)C3=C(N=CC=C3)N2C4CC4",2.293,3,1,1]
["S1743","Esomeprazole magnesium","h11","L3800-05","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","N/A","Marketed","ATPase,Proton Pump","Transmembrane Transporters","Esomeprazole Magnesium(NEXIUM) is a proton pump inhibitor to reduce gastric acid secretion through inhibition of H(+)/K(+)-ATPase in gastric parietal cells.",713.12,"161973-10-0",{"v":143,"d":"143.00"},200.53,"<1","N/A","http://selleckchem.com/products/nexium-esomeprazole-magnesium.html","C34H36MgN6O6S2","Magnesium salt","NEXIUM","[Mg++].COC1=CC2=C([N-]C(=N2)[S](=O)CC3=C(C)C(=C(C)C=N3)OC)C=C1.COC4=CC5=C([N-]C(=N5)[S](=O)CC6=NC=C(C)C(=C6C)OC)C=C4",{"v":6.1,"d":"6.100"},10,0,10]
["S1744","Nicotinic Acid","a2","L3800-06","in 10mM DMSO","DMF,EMA,HMA,CFDA,PMDA","USP42-NF37;EP9.3;BP2019;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Vitamin","Metabolism","Nicotinic Acid is a water-soluble vitamin belonging to the vitamin B family.",123.11,"59-67-6",{"v":25,"d":"25.00"},203.07,{"v":2,"d":"2.00"},16.25,"http://selleckchem.com/products/Niacin(Nicotinic-acid).html","C6H5NO2","free base","N/A","OC(=O)C1=CC=CN=C1",0.309,2,0,1]
["S1747","Nimodipine","b2","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,Calcium Channel","Transmembrane Transporters","Nimodipine (BAY E 9736) is a dihydropyridine calcium channel blocker and an autophagy inhibitor, used in the treatment of high blood pressure.",418.44,"66085-59-4",{"v":84,"d":"84.00"},200.75,"<1","N/A","http://selleckchem.com/products/Nimodipine(Nimotop).html","C21H26N2O7","free base","BAY E 9736","COCCOC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OC(C)C)C",2.361,5,1,10]
["S1748","Nisoldipine","c2","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Phase 4","Calcium Channel","Transmembrane Transporters","Nisoldipine (Sular, BAY K 5552) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM.",388.41,"63675-72-9",{"v":77,"d":"77.00"},198.24,"<1","N/A","http://selleckchem.com/products/Nisoldipine(Sular).html","C20H24N2O6","free base","BAY K 5552","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC=C2[N+]([O-])=O)C(=O)OCC(C)C)C",2.958,4,1,8]
["S1750","Octocrylene","d2","L3800-06","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","N/A","Others","Others","Octocrylene is an organic compound used as an ingredient in sunscreens and cosmetics.",361.48,"6197-30-4","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/octocrylene.html","C24H27NO2","free base","N/A","CCCCC(CC)COC(=O)C(C#N)=C(C1=CC=CC=C1)C2=CC=CC=C2",6.487,2,0,10]
["S1754","Oxybutynin","e2","L3800-06","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","AChR","Neuronal Signaling","Oxybutynin is a competitive antagonist of the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor, used to relieve urinary and bladder difficulties.",357.49,"5633-20-5",{"v":71,"d":"71.00"},198.61,"<1","N/A","http://selleckchem.com/products/Oxybutynin(Ditropan).html","C22H31NO3","Free Base","N/A","CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)C2=CC=CC=C2",4.646,2,0,10]
["S1756","Enoxacin","f2","L3800-06","in 10mM DMSO","FDA,DMF,CFDA","KP Ⅹ;JP17;CP2005;Martindale:The Extra Pharmacopoeia","N/A","Topoisomerase","DNA Damage/DNA Repair","Enoxacin (AT-2266, CI919, Pd107779, NSC 629661) is an oral broad-spectrum fluoroquinolone antibacterial agent by inhibiting bacterial DNA gyrase and topoisomerase IV, used to treat a wide variety of infections.",320.32,"74011-58-8",{"v":32,"d":"32.00"},{"v":99.9,"d":"99.90"},"<1","N/A","http://selleckchem.com/products/Enoxacin(Penetrex).html","C15H17FN4O3","free base","AT-2266, CI919, Pd107779, NSC 629661","CCN1C=C(C(O)=O)C(=O)C2=CC(=C(N=C12)N3CCNCC3)F",-1.483,3,1,3]
["S1759","Pitavastatin (NK-104) calcium","g2","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,COVID-19,HMG-CoA Reductase,Mitophagy","Metabolism","Pitavastatin Calcium (NK-104, P-872441, itavastatin, nisvastatin), a novel member of the medication class of statins, is a calcium salt formulation of pitavastatin which is a highly effective HMG-CoA reductase inhibitor. Pitavastatin Calcium attenuates AGEs-induced mitophagy via inhibition of ROS generation. Pitavastatin Calcium induces autophagy and apoptosis.",880.98,"147526-32-7",{"v":51,"d":"51.00"},57.89,"<1","N/A","http://selleckchem.com/products/Pitavastatin-calcium(Livalo).html","C50H46CaF2N2O8","Calcium salt","NK-104, P-872441, itavastatin, nisvastatin","[Ca++].OC(CC(O)C=CC1=C(C2=CC=C(F)C=C2)C3=CC=CC=C3N=C1C4CC4)CC([O-])=O.OC(CC(O)C=CC5=C(C6=CC=C(F)C=C6)C7=CC=CC=C7N=C5C8CC8)CC([O-])=O",{"v":4.96,"d":"4.960"},2,4,16]
["S1760","Rifapentine","h2","L3800-06","in 10mM DMSO","FDA,CFDA,NDC","Martindale:The Extra Pharmacopoeia","Marketed","DNA/RNA Synthesis","DNA Damage/DNA Repair","Rifapentine (MDL473) is an antibiotic, which inhibits DNA-dependent RNA polymerase activity, used to treat tuberculosis.",877.03,"61379-65-5",{"v":100,"d":"100.00"},114.02,"<1","N/A","http://selleckchem.com/products/Rifapentine(Priftin).html","C47H64N4O12","free base","MDL473","COC1\\C=C\\OC2(C)OC3=C(C2=O)C4=C(O)C(=C(NC(=O)\\C(=C\\C=C\\C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)C)C(=C4C(=C3C)O)O)\\C=N\\N5CCN(CC5)C6CCCC6",4.664,8,6,6]
["S1761","Suprofen","a3","L3800-06","in 10mM DMSO","FDA,DMF,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","N/A","COX","Neuronal Signaling","Suprofen(TN-762) is a dual COX-1/COX-2 inhibitor, used as a non-steroidal anti-inflammatory analgesic and antipyretic.",260.31,"40828-46-4",{"v":52,"d":"52.00"},199.76,"<1","N/A","http://selleckchem.com/products/Suprofen(Profenal).html","C14H12O3S","free base","TN-762","CC(C(O)=O)C1=CC=C(C=C1)C(=O)C2=CC=CS2",3.314,2,0,4]
["S1762","Pyrazinamide","b3","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Bacterial","Microbiology","Pyrazinamide (Pyrazinoic Acid Amide) is an agent used to treat tuberculosis.",123.11,"98-96-4",{"v":25,"d":"25.00"},203.07,{"v":12,"d":"12.00"},97.47,"http://selleckchem.com/products/Pyrazinamide(Pyrazinoic-acid-amide).html","C5H5N3O","free base","Pyrazinoic Acid Amide","NC(=O)C1=NC=CN=C1",-1.041,3,1,1]
["S1763","Quetiapine (ICI-204636) fumarate","c3","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.6;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Dopamine Receptor","Neuronal Signaling","Quetiapine Fumarate (ICI-204636) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression and shows affinity for various neurotransmitter receptors including serotonin, dopamine, histamine, and adrenergic receptors.",883.09,"111974-72-2",{"v":36,"d":"36.00"},40.77,"<1","N/A","http://selleckchem.com/products/Quetiapine-fumarate(Seroquel).html","C46H54N6O8S2","Fumarate","ICI-204636 fumarate","OCCOCCN1CCN(CC1)C2=NC3=CC=CC=C3SC4=C2C=CC=C4.OCCOCCN5CCN(CC5)C6=NC7=CC=CC=C7SC8=C6C=CC=C8.OC(=O)\\C=C\\C(O)=O",-0.718,6,2,14]
["S1764","Rifampin (NSC-113926)","d3","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;IP2010","Phase 2","Antibiotics for Plant Cell Culture,Antineoplastic and Immunosuppressive Antibiotics,DNA/RNA Synthesis,Selection Antibiotics for Transfected Cell","DNA Damage/DNA Repair","Rifampin (NSC-113926, Rimactane, Rifampicin) is a DNA-dependent RNA polymerase inhibitor, used to treat a number of bacterial infections.",822.94,"13292-46-1",{"v":100,"d":"100.00"},121.52,"<1","N/A","http://selleckchem.com/products/Rifampin(Rifadin).html","C43H58N4O12","free base","Rimactane, Rifampicin,NSC-113926","COC1\\C=C\\OC2(C)OC3=C(C2=O)C4=C(O)C(=C(NC(=O)\\C(=C\\C=C\\C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)C)C(=C4C(=C3C)O)O)\\C=N\\N5CCN(C)CC5",3.262,8,6,5]
["S1768","Cefditoren Pivoxil","e3","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","KP Ⅹ;JP17;USP32-NF27;Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics,Bacterial","Microbiology","Cefditoren Pivoxil (ME-1207) is a broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria.",620.72,"117467-28-4",{"v":100,"d":"100.00"},{"v":161.1,"d":"161.10"},"<1","N/A","http://selleckchem.com/products/Cefditoren-pivoxil.html","C25H28N6O7S3","free base","ME-1207","CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C)\\C=C/C3=C(C)N=CS3)C4=CSC(=N4)N",1.926,10,2,12]
["S1770","Sulfadiazine","f3","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics","Microbiology","Sulfadiazine is a sulfonamide antibiotic.",250.28,"68-35-9",{"v":50,"d":"50.00"},199.78,"<1","N/A","http://selleckchem.com/products/Sulfadiazine.html","C10H10N4O2S","free base","N/A","NC1=CC=C(C=C1)[S](=O)(=O)NC2=NC=CC=N2",0.313,4,2,3]
["S1771","Chlorprothixene","g3","L3800-06","in 10mM DMSO","FDA,CFDA","EP9.8;BP2019;Martindale:The Extra Pharmacopoeia","N/A","Dopamine Receptor","Neuronal Signaling","Chlorprothixene(Minithixen,Truxal) has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively.",315.86,"113-59-7",{"v":6,"d":"6.00"},{"v":19,"d":"19.00"},"<1","N/A","http://selleckchem.com/products/Chlorprothixene.html","C18H18ClNS","free base","Minithixen,Truxal","CN(C)CC/C=C1/C2=CC=CC=C2SC3=C1C=C(Cl)C=C3",5.123,0,0,3]
["S1773","Oxytetracycline (Terramycin)","h3","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,PMDA","EP9.2;JP17;BP2017;USP40-NF35;Ph.Int_5th ;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","Antibiotics,Bacterial,Selection Antibiotics for Transfected Cell","Others","Oxytetracycline(Terramycin) is a broad-spectrum tetracycline antibiotic, used to treat infections with bacteria.",460.43,"79-57-2",{"v":92,"d":"92.00"},199.81,"<1","N/A","http://selleckchem.com/products/Oxytetracycline(Terramycin).html","C22H24N2O9","free base","Terramycin","CN(C)C1C2C(O)C3C(=C(O)C4=C(C=CC=C4O)C3(C)O)C(=O)C2(O)C(=O)C(=C1O)C(N)=O",-1.904,3,5,2]
["S1774","Thioguanine (NSC 752)","a4","L3800-06","in 10mM DMSO","FDA,NDC","USP42-NF37","N/A","DNA Methyltransferase","Epigenetics","Thioguanine (NSC 752, 6-Thioguanine, 2-Amino-6-purinethiol), a purine antimetabolite, inhibits DNMT1 activity through ubiquitin-targeted degradation, used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis) and organ transplant recipients.",167.19,"154-42-7",{"v":9,"d":"9.00"},53.83,"<1","N/A","http://selleckchem.com/products/Thioguanine.html","C5H5N5S","free base","NSC 752,6-Thioguanine, 2-Amino-6-purinethiol","NC1=NC(=S)C2=C(N1)N=C[NH]2",0.236,2,3,0]
["S1775","Thiotepa","b4","L3800-06","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","USP42-NF37;BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia","Marketed","Antineoplastic and Immunosuppressive Antibiotics","Others","Thiotepa (Thioplex, Tiofosyl, Tiofosfamid, Triethylenethiophosphoramide) is an alkylating agent used to treat cancer.",189.22,"52-24-4",{"v":100,"d":"100.00"},528.49,{"v":100,"d":"100.00"},528.49,"http://selleckchem.com/products/thiotepa-thioplex.html","C6H12N3PS","free base","Tiofosyl, Tiofosfamid, Triethylenethiophosphoramide","S=[P](N1CC1)(N2CC2)N3CC3",-0.762,0,0,3]
["S1776","Toremifene Citrate (NK 622)","c4","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Toremifene Citrate (NK 622, NSC 613680) is an oral selective estrogen receptor modulator (SERM), used in the treatment of advanced breast cancer.",598.08,"89778-27-8",{"v":100,"d":"100.00"},{"v":167.2,"d":"167.20"},"<1","N/A","http://selleckchem.com/products/Toremifene-Citrate(Fareston).html","C32H36ClNO8","Citrate","NSC 613680,NK 622 Citrate","CN(C)CCOC1=CC=C(C=C1)\\C(=C(CCCl)/C2=CC=CC=C2)C3=CC=CC=C3.OC(=O)CC(O)(CC(O)=O)C(O)=O",1.945,4,0,14]
["S1777","Ethionamide","d4","L3800-06","in 10mM DMSO","FDA,DMF,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","N/A","Antibiotics","Microbiology","Ethionamide (Bayer 5312) is an antibiotic used in the treatment of tuberculosis.",166.24,"536-33-4",{"v":33,"d":"33.00"},198.51,"<1","N/A","http://selleckchem.com/products/Ethionamide.html","C8H10N2S","free base","Bayer 5312","CCC1=NC=CC(=C1)C(N)=S",1.498,1,1,2]
["S1778","Trifluridine (NSC 75520)","e4","L3800-06","in 10mM DMSO","FDA,DMF,EMA,NDC","USP42-NF37;BP2019;Martindale:The Extra Pharmacopoeia","Marketed","DNA/RNA Synthesis,Thymidylate Synthase","DNA Damage/DNA Repair","Trifluridine (NSC 529182, NSC 75520, Viroptic, Trifluorothymidine, TFT) is an anti-herpesvirus antiviral agent by interacting viral DNA replication, used primarily on the eye.",{"v":296.2,"d":"296.20"},"70-00-8",{"v":59,"d":"59.00"},199.19,{"v":59,"d":"59.00"},199.19,"http://selleckchem.com/products/Trifluridine(Viroptic).html","C10H11F3N2O5","free base","NSC 529182, NSC 75520, Viroptic, Trifluorothymidine, TFT","OCC1OC(CC1O)N2C=C(C(=O)NC2=O)C(F)(F)F",-0.782,3,3,3]
["S1782","Azacitidine (5-Azacytidine)","f4","L3800-06","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,DNA Methyltransferase,Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Azacitidine (5-Azacytidine, 5-AzaC, Ladakamycin, AZA, 5-Aza, CC-486,NSC 102816) is a nucleoside analogue of cytidine that specifically inhibits DNA methylation by trapping DNA methyltransferases. Azacitidine induces mitochondrial apoptosis and autophagy.",{"v":244.2,"d":"244.20"},"320-67-2",{"v":48,"d":"48.00"},196.56,"<1","N/A","http://selleckchem.com/products/Azacitidine(Vidaza).html","C8H12N4O5","free base","5-AzaC,Ladakamycin, AZA,5-Aza, CC-486,NSC 102816,5-Azacytidine","NC1=NC(=O)N(C=N1)C2OC(CO)C(O)C2O",-2.505,4,4,2]
["S1784","Vidarabine","g4","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,PMDA","USP36-NF31;Martindale:The Extra Pharmacopoeia","Phase 3","DNA/RNA Synthesis","DNA Damage/DNA Repair","Vidarabine is an antiviral drug by interfering with the synthesis of viral DNA, used to treat herpes simplex and varicella zoster viruses.",267.24,"5536-17-4",{"v":53,"d":"53.00"},198.32,{"v":3,"d":"3.00"},11.23,"http://selleckchem.com/products/Vidarabine(Vira-A).html","C10H13N5O4","free base","N/A","NC1=C2N=C[N](C3OC(CO)C(O)C3O)C2=NC=N1",-1.881,4,4,2]
["S1786","Verteporfin (CL 318952)","h4","L3800-06","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,TEAD,VDA,YAP","Angiogenesis","Verteporfin (CL 318952, Visudyne) is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth.  It is also a potent second-generation photosensitizing agent derived from porphyrin. Verteporfin is an autophagy inhibitor. Verteporfin inhibits cell proliferation and induces apoptosis.",718.79,"129497-78-5",{"v":100,"d":"100.00"},139.12,"<1","N/A","http://selleckchem.com/products/Verteporfin(Visudyne).html","C41H42N4O8","free base","CL 318952, Visudyne","COC(=O)CCC1=C(C)C2=CC3=NC(=CC4=C(C)C(=C([NH]4)C=C5N=C(C=C1[NH]2)C(=C5C)CCC(O)=O)C=C)C6=CC=C(C(C(=O)OC)C36C)C(=O)OC",7.789,9,2,12]
["S1787","Teniposide","a5","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","Phase 2","Topoisomerase","DNA Damage/DNA Repair","Teniposide (NSC 122819, VM-26) is a chemotherapeutic medication mainly used in the treatment of childhood acute lymphocytic leukemia (ALL).",656.65,"29767-20-2",{"v":40,"d":"40.00"},60.92,"<1","N/A","http://selleckchem.com/products/Teniposide(Vumon).html","C32H32O13S","free base","NSC 122819, VM-26","COC1=CC(=CC(=C1O)OC)C2C3C(COC3=O)C(OC4OC5COC(OC5C(O)C4O)C6=CC=CS6)C7=CC8=C(OCO8)C=C27",2.516,10,3,6]
["S1789","Tetrabenazine (Xenazine)","b5","L3800-06","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia","Marketed","Dopamine Receptor","Neuronal Signaling","Tetrabenazine(Xenazine,Ro 1-9569) acts primarily as a reversible high-affinity inhibitor of mono-amine uptake into granular vesicles of presynaptic neurons by binding selectively to VMAT-2; Also blocks dopamine D2 receptors, but this affinity is 1,000-fold lower than its affinity for VMAT-2.",317.42,"58-46-8",{"v":58,"d":"58.00"},182.72,"<1","N/A","http://selleckchem.com/products/Tetrabenazine(Nitoman).html","C19H27NO3","free base","Xenazine,Ro 1-9569","COC1=CC2=C(C=C1OC)C3CC(=O)C(CC(C)C)CN3CC2",3.365,3,0,4]
["S1790","Rifaximin","c5","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","BP2019;EP9.2;KP Ⅹ;Martindale:The Extra Pharmacopoeia","Marketed","DNA/RNA Synthesis","DNA Damage/DNA Repair","Rifaximin is a RNA synthesis inhibitor by binding the β subunit of the bacterial DNA-dependent RNA polymerase, used to treat traveler's diarrhea caused by certain bacteria.",785.88,"80621-81-4",{"v":47,"d":"47.00"},59.81,"<1","N/A","http://selleckchem.com/products/Rifaximin(Xifaxan).html","C43H51N3O11","free base","N/A","COC1\\C=C\\OC2(C)OC3=C(C2=O)C4=C(C(=C3C)O)C(=C(NC(=O)\\C(=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)C)C5=C4N=C6C=C(C)C=C[N]56)O",4.805,8,5,3]
["S1791","Bacitracin Zinc","d5","L3800-06","in 10mM DMSO","FDA,NDC,DMF","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,KP Ⅹ,BP2017,Ph.Int_5th","N/A","Antibiotics,Bacterial","Microbiology","Bacitracin(Zinc Bacitracin) is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane. It inhibits cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.",1486.07,"1405-89-6",{"v":100,"d":"100.00"},67.29,"<1","N/A","http://www.selleck.cn/products/bacitracin-zinc.html","C66H101N17O16SZn","Free Base","Zinc Bacitracin","[Zn++].CCC(C)C(N)C1=NCC(S1)C(=O)NC(CC(C)C)C(=O)NC(CCC([O-])=O)C(=O)NC(C(C)CC)C(=O)NC2CCCCNC(=O)C(CC(N)=O)NC(=O)C(CC([O-])=O)NC(=O)C(CC3=C[NH]C=N3)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(NC(=O)C(CCCN)NC2=O)C(C)CC",-3.993,14,15,31]
["S1792","Simvastatin (MK 733)","e5","L3800-06","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.7;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,Ferroptosis,HMG-CoA Reductase,Mitophagy","Metabolism","Simvastatin (MK-0733, MK 733) is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM in cell-free assays. Simvastatin induces ferroptosis, mitophagy, autophagy and apoptosis.",418.57,"79902-63-9",{"v":83,"d":"83.00"},198.29,"<1","N/A","http://selleckchem.com/products/Simvastatin(Zocor).html","C25H38O5","free base","MK-0733, MK 733","CCC(C)(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C12",4.634,4,1,7]
["S1793","Ramipril","f5","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;EP9.8;;BP2019;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","ACE,RAAS","Endocrinology & Hormones","Ramipril(HOE-498) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.",416.51,"87333-19-5",{"v":83,"d":"83.00"},199.27,"<1","N/A","http://selleckchem.com/products/Ramipril(Altace).html","C23H32N2O5","free base","HOE-498","CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCC3CC2C(O)=O",0.308,4,1,10]
["S1794","Fenofibrate (NSC-281319)","g5","L3800-06","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,P450 (e.g. CYP17),PPAR","Metabolism","Fenofibrate (NSC-281319) is a compound of the fibrate class and fibric acid derivative. Fenofibrate is a selective agonist of PPARα with EC50 of 30 μM. Fenofibrate binds to and inhibits cytochrome P450 epoxygenase (CYP)2C with IC50 of 0.2 μM, 0.7 μM and 9.7 μM for CYP2C19, CYP2B6 and CYP2C9, respectively. Fenofibrate induces autophagy.",360.83,"49562-28-9",{"v":72,"d":"72.00"},199.54,"<1","N/A","http://selleckchem.com/products/Fenofibrate(Tricor).html","C20H21ClO4","free base","NSC-281319","CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(Cl)C=C2",5.111,4,0,7]
["S1799","Ranolazine","h5","L3800-06","in 10mM DMSO","FDA,DMF,EMA,NDC","Martindale:The Extra Pharmacopoeia","Marketed","Calcium Channel","Transmembrane Transporters","Ranolazine (CVT 303, RS 43285-003) is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina.",427.54,"95635-55-5",{"v":86,"d":"86.00"},201.15,"<1","N/A","http://selleckchem.com/products/Ranolazine(Ranexa).html","C24H33N3O4","Free Base","CVT 303, RS 43285-003","COC1=CC=CC=C1OCC(O)CN2CCN(CC2)CC(=O)NC3=C(C)C=CC=C3C",2.991,3,2,9]
["S1801","Ranitidine Hydrochloride","a6","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.6;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Histamine Receptor","Neuronal Signaling","Ranitidine (AH19065) is a histamine H2-receptor antagonist, used to treat stomach or intestinal ulcers.",350.86,"66357-59-3",{"v":70,"d":"70.00"},199.51,{"v":70,"d":"70.00"},199.51,"http://selleckchem.com/products/Ranitidine-hydrochloride(Zantac).html","C13H22N4O3S.HCl","Hydrochloride","AH19065","Cl.CNC(/NCCSCC1=CC=C(CN(C)C)O1)=C\\[N+]([O-])=O",1.421,1,2,10]
["S1805","Acetylcholine Chloride","b6","L3800-06","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,BP2017,KP Ⅹ,JP17","N/A","AChR","Neuronal Signaling","The chemical compound Acetylcholine Chloride(ACh chloride) is a neurotransmitter in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans.",181.66,"60-31-1",{"v":36,"d":"36.00"},198.17,{"v":36,"d":"36.00"},198.17,"http://www.selleck.cn/products/Acetylcholine-chloride.html","C7H16NO2.Cl","Chloride","ACh chloride","[Cl-].CC(=O)OCC[N+](C)(C)C",-3.869,2,0,4]
["S1806","Acipimox","c6","L3800-06","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","Marketed","Others","Others","Acipimox (Olbemox,K-9321) is a niacin derivative used as a hypolipidemic agent.",154.12,"51037-30-0",{"v":31,"d":"31.00"},201.14,"<1","N/A","http://selleckchem.com/products/Acipimox.html","C6H6N2O3","free base","Olbemox,K-9321","CC1=CN=C(C=[N+]1[O-])C(O)=O",-0.975,2,0,1]
["S1807","Aciclovir (BW 248U)","d6","L3800-06","in 10mM DMSO","DMF,CFDA,PMDA,HMA","BP2019;EP9.2;Ph.Int_6th;JP17;IP2010;CP2005;EP9.1;BP2017\nUSP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Antiviral,Apoptosis related,DNA/RNA Synthesis,Nucleoside Analog/Antimetabolite","Microbiology","Acyclovir (Acyclovir, Acycloguanosine, Zovirax, ACV, NSC 645011,BW 248U) is a synthetic nucleoside analogue active against herpesviruses. Acyclovir induces cell cycle perturbation and apoptosis in Jurkat leukemia cells.",{"v":225.2,"d":"225.20"},"59277-89-3",{"v":45,"d":"45.00"},199.82,"<1","N/A","http://selleckchem.com/products/Acyclovir(Aciclovir).html","C8H11N5O3","free base","Acyclovir, Acycloguanosine, Zovirax, ACV, NSC 645011,BW 248U","NC1=NC2=C(N=C[N]2COCCO)C(=O)N1",-1.423,4,3,4]
["S1808","Nifedipine (BAY-a-1040)","e6","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","Calcium Channel","Transmembrane Transporters","Nifedipine (BAY-a-1040) is a dihydropyridine calcium channel blocker, used to lower hypertension and to treat angina.",346.33,"21829-25-4",{"v":69,"d":"69.00"},199.23,"<1","N/A","http://selleckchem.com/products/Nifedipine(Adalat).html","C17H18N2O6","free base","BAY-a-1040","COC(=O)C1=C(C)NC(=C(C1C2=C(C=CC=C2)[N+]([O-])=O)C(=O)OC)C",1.766,4,1,6]
["S1811","Amiloride (MK-870) HCl","f6","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;EP9.7;BP2019;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Calcium Channel,Serine Protease,Sodium Channel","Transmembrane Transporters","Amiloride (MK-870 HCl) is a selective T-type calcium channel blocker, an epithelial sodium channel blocker and a selective inhibitor of urokinase plasminogen activator (uPA)(Ki=7 μM).",266.09,"2016-88-8",{"v":53,"d":"53.00"},199.18,{"v":6,"d":"6.00"},22.55,"http://selleckchem.com/products/Amiloride-hydrochloride(Midamor).html","C6H8ClN7O.HCl","Hydrochloride","MK-870 HCl","Cl.NC(=N)NC(=O)C1=NC(=C(N)N=C1N)Cl",-0.366,3,4,2]
["S1813","Amlodipine Besylate","g6","L3800-06","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","Calcium Channel","Transmembrane Transporters","Amlodipine Besylate is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.",567.05,"111470-99-6",{"v":113,"d":"113.00"},199.28,"<1","N/A","http://selleckchem.com/products/Amlodipine-besylate(Norvasc).html","C20H25ClN2O5.C6H6O3S","Besylate","N/A","CCOC(=O)C1=C(COCCN)NC(=C(C1C2=C(Cl)C=CC=C2)C(=O)OC)C.O[S](=O)(=O)C3=CC=CC=C3",2.739,5,2,11]
["S1816","Chlorpheniramine Maleate","h6","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;KP Ⅹ;JP17;IP2010","N/A","Histamine Receptor","Neuronal Signaling","Chlorpheniramine Maleate (Chlorpheniramine maleate, Chlorphenamine, NCI-C55265) is an histamine H1 receptor antagonist with IC50 of 12 nM.",390.86,"113-92-8",{"v":78,"d":"78.00"},199.56,{"v":78,"d":"78.00"},199.56,"http://selleckchem.com/products/Chlorpheniramine-maleate.html","C16H19ClN2.C4H4O4","Maleate","NCI-C55265","CN(C)CCC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.OC(=O)\\C=C/C(O)=O",{"v":0.7,"d":"0.700"},3,0,7]
["S1820","Clofibrate","a7","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,PMDA","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,KP Ⅹ,JP17,BP2017","N/A","Others","Others","Clofibrate (Atromid-S), a fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia.",{"v":242.7,"d":"242.70"},"637-07-0",{"v":7,"d":"7.00"},28.84,"<1","N/A","http://www.selleck.cn/products/Clofibrate(Atromid-S).html","C12H15ClO3","Free Base","N/A","CCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1",3.329,3,0,5]
["S1823","Fenoprofen Calcium","b7","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia","N/A","Immunology & Inflammation related","Immunology & Inflammation","Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.",{"v":522.6,"d":"522.60"},"34597-40-5",{"v":105,"d":"105.00"},200.92,"<1","N/A","http://selleckchem.com/products/fenoprofen-calcium.html","C30H26CaO6","Calcium salt","N/A","[Ca++].CC(C([O-])=O)C1=CC(=CC=C1)OC2=CC=CC=C2.CC(C([O-])=O)C3=CC(=CC=C3)OC4=CC=CC=C4",4.086,2,0,8]
["S1825","Erdosteine","c7","L3800-06","in 10mM DMSO","CFDA,HMA","Martindale:The Extra Pharmacopoeia","Marketed","NF-κB","NF-κB","Erdosteine (KW-9144,RV 144) is a mucolytic which is used in treatment of excessive viscous mucus. Erdosteine inhibits lipopolysaccharide (LPS)-induced NF-κB activation.",249.31,"84611-23-4",{"v":50,"d":"50.00"},200.55,"<1","N/A","http://selleckchem.com/products/erdosteine.html","C8H11NO4S2","free base","KW-9144,RV 144","OC(=O)CSCC(=O)NC1CCSC1=O",-0.382,3,1,5]
["S1827","Betaxolol HCl","d7","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Phase 3","Adrenergic Receptor","Neuronal Signaling","Betaxolol (SL 75212) is a β1 adrenergic receptor blocker with IC50 of 6 μM.",343.89,"63659-19-8",{"v":69,"d":"69.00"},200.65,{"v":69,"d":"69.00"},200.65,"http://selleckchem.com/products/betaxolol-hydrochloride-betoptic.html","C18H29NO3.HCl","Hydrochloride","SL 75212 HCl","Cl.CC(C)NCC(O)COC1=CC=C(CCOCC2CC2)C=C1",2.959,2,2,11]
["S1828","Proparacaine HCl","e7","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37","N/A","Sodium Channel","Transmembrane Transporters","Proparacaine HCl(Proxymetacaine Hydrochloride) is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM.",330.85,"5875-06-9",{"v":12,"d":"12.00"},36.27,{"v":66,"d":"66.00"},199.49,"http://selleckchem.com/products/proparacaine-hcl.html","C16H26N2O3.HCl","Hydrochloride","Proxymetacaine Hydrochloride","Cl.CCCOC1=C(N)C=C(C=C1)C(=O)OCCN(CC)CC",3.013,3,1,10]
["S1829","Pranlukast","f7","L3800-06","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","Immunology & Inflammation related","Immunology & Inflammation","Pranlukast (ONO-1078,ono-rs-411) is an orally administered, and selective antagonist of the cysteinyl leukotrienes (LT) C(4), LTD(4) and LTE(4), used in the prophylactic treatment of chronic bronchial asthma.",{"v":481.5,"d":"481.50"},"103177-37-3",{"v":11,"d":"11.00"},22.85,"<1","N/A","http://selleckchem.com/products/pranlukast.html","C27H23N5O4","free base","ONO-1078,ono-rs-411","O=C(NC1=CC2=C(C=C1)C(=O)C=C(O2)C3=NN=N[NH]3)C4=CC=C(OCCCCC5=CC=CC=C5)C=C4",4.232,7,2,9]
["S1830","Oxfendazole","g7","L3800-06","in 10mM DMSO","N/A","USP42-NF37;BP2019;EP9.8;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Parasite","Microbiology","Oxfendazole (RS-8858,Fenbendazole sulfoxide) is a broad spectrum benzimidazole anthelmintic.",315.35,"53716-50-0",{"v":10,"d":"10.00"},31.71,"<1","N/A","http://selleckchem.com/products/oxfendazole.html","C15H13N3O3S","free base","RS-8858,Fenbendazole sulfoxide","COC(=O)NC1=NC2=C([NH]1)C=C(C=C2)[S](=O)C3=CC=CC=C3",2.657,4,2,4]
["S1831","Carvedilol","h7","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Carvedilol (BM-14190, SKF 105517) is a non-selective beta blocker/alpha-1 blocker, used to treat congestive heart failure (CHF) and high blood pressure.",406.47,"72956-09-3",{"v":81,"d":"81.00"},199.28,"<1","N/A","http://selleckchem.com/products/carvedilol.html","C24H26N2O4","free base","BM-14190, SKF 105517","COC1=CC=CC=C1OCCNCC(O)COC2=C3C(=CC=C2)[NH]C4=C3C=CC=C4",4.014,3,3,10]
["S1832","Atracurium Besylate","a8","L3800-06","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;KP Ⅹ","Phase 4","AChR","Neuronal Signaling","Atracurium Besylate (BW 33A, 51W89) is a neuromuscular blocking agent with ED95 of 0.2 mg/kg.",1243.48,"64228-81-5",{"v":100,"d":"100.00"},80.42,{"v":33,"d":"33.00"},26.54,"http://selleckchem.com/products/atracurium-besylate.html","C53H72N2O12.2(C6H5O3S)","Dibesylate","BW 33A, 51W89","COC1=CC=C(CC2C3=CC(=C(OC)C=C3CC[N+]2(C)CCC(=O)OCCCCCOC(=O)CC[N+]4(C)CCC5=CC(=C(OC)C=C5C4CC6=CC=C(OC)C(=C6)OC)OC)OC)C=C1OC.[O-][S](=O)(=O)C7=CC=CC=C7.[O-][S](=O)(=O)C8=CC=CC=C8",3.646,12,0,28]
["S1833","Butoconazole nitrate","b8","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","Phase 3","Fungal,IFN,Interleukins,TNF-alpha","Microbiology","Butoconazole nitrate (RS-35887) is an anti-fungal agent that inhibits PHA-stimulated release of cytokines-- IL-2, TNFα, IFN and GM-CSF from human peripheral blood lymphocytes (IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively).",474.79,"64872-77-1",{"v":95,"d":"95.00"},200.09,"<1","N/A","http://selleckchem.com/products/butoconazole-nitrate.html","C19H17Cl3N2S.HNO3","Nitrate","RS-35887","O[N+]([O-])=O.ClC1=CC=C(CCC(C[N]2C=CN=C2)SC3=C(Cl)C=CC=C3Cl)C=C1",5.238,1,0,7]
["S1835","Azithromycin (CP-62993)","c8","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.3;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics,Antibiotics for Mammalian Cell Culture,Autophagy,Bacterial,COVID-19","Autophagy","Azithromycin (CP-62993, XZ-450) is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.",748.98,"83905-01-5",{"v":100,"d":"100.00"},133.51,"<1","N/A","http://selleckchem.com/products/azithromycin-zithromax.html","C38H72N2O12","Free Base","XZ-450,CP-62993","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)CN(C)C(C)C(O)C1(C)O",2.078,7,3,7]
["S1836","Albendazole Oxide","d8","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.4;BP2019;KP Ⅹ;Ph.Int_6th;Martindale:The Extra Pharmacopoeia","N/A","Microtubule Associated","Cytoskeletal Signaling","Albendazole Oxide (Ricobendazole,Albendazole sulfoxide) is a tubulin polymerization or assembly inhibitor, used for the treatment of a variety of parasitic worm infestations.",281.33,"54029-12-8",{"v":11,"d":"11.00"},{"v":39.1,"d":"39.10"},"<1","N/A","http://selleckchem.com/products/albendazole-oxide-ricobendazole.html","C12H15N3O3S","free base","Ricobendazole,Albendazole sulfoxide","CCC[S](=O)C1=CC2=C(C=C1)N=C(NC(=O)OC)[NH]2",1.953,4,2,5]
["S1839","Chloroxine","e8","L3800-06","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia","N/A","Bacterial","Microbiology","Chloroxine is a synthetic antibacterial compound that is effective in the treatment of dandruff and seborrheic dermatitis when incorporated in a shampoo.",214.05,"773-76-2",{"v":43,"d":"43.00"},200.89,"<1","N/A","http://selleckchem.com/products/Chloroxine.html","C9H5Cl2NO","free base","N/A","OC1=C(Cl)C=C(Cl)C2=C1N=CC=C2",3.103,1,1,0]
["S1840","Lomustine","f8","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Phase 2","DNA/RNA Synthesis","DNA Damage/DNA Repair","Lomustine (NSC79037, Gleostine, CeeNU, CCNU) inhibits cancer cells by damaging the DNA and stops cells from dividing.",{"v":233.7,"d":"233.70"},"13010-47-4",{"v":46,"d":"46.00"},196.83,"<1","N/A","http://selleckchem.com/products/Lomustine(CeeNU).html","C9H16ClN3O2","free base","NSC79037, Gleostine, CeeNU, CCNU","ClCCN(N=O)C(=O)NC1CCCCC1",2.394,2,1,4]
["S1843","Chenodeoxycholic Acid","g8","L3800-06","in 10mM DMSO","DMF,EMA,CFDA,PMDA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Marketed","FXR","Metabolism","Chenodeoxycholic Acid (Chenodiol, Chenodesoxycholic acid, Chenocholic acid,CDCA) is a naturally occurring human bile acid, and inhibits production of cholesterol in the liver and absorption in the intestines. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.",392.57,"474-25-9",{"v":79,"d":"79.00"},201.24,"<1","N/A","http://selleckchem.com/products/Chenodeoxycholic-acid.html","C24H40O4","free base","Chenodiol, Chenodesoxycholic acid, Chenocholic acid,CDCA","CC(CCC(O)=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C",4.014,1,2,4]
["S1845","Cimetidine","h8","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.4;BP2019;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Histamine Receptor","Neuronal Signaling","Cimetidine (SKF-92334), a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.",252.34,"51481-61-9",{"v":51,"d":"51.00"},202.11,"<1","N/A","http://selleckchem.com/products/Cimetidine(Tagamet).html","C10H16N6S","free base","SKF-92334","CNC(NCCSCC1=C(C)[NH]C=N1)=NC#N",0.007,2,3,7]
["S1847","Clemastine (HS-592) fumarate","a9","L3800-06","in 10mM DMSO","FDA,NDC,PMDA","USP42-NF37;EP9.3;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","N/A","Autophagy,Histamine Receptor,mTOR","Neuronal Signaling","Clemastine Fumarate (HS-592, Meclastine) is a selective histamine H1 receptor antagonist with IC50 of 3 nM. Clemastine stimulates autophagy via mTOR pathway.",459.96,"14976-57-9",{"v":35,"d":"35.00"},76.09,"<1","N/A","http://selleckchem.com/products/Clemastine-Fumarate.html","C21H26ClNO.C4H4O4","Fumarate","HS-592 fumarate, Meclastine fumarate","CN1CCCC1CCOC(C)(C2=CC=CC=C2)C3=CC=C(Cl)C=C3.OC(=O)\\C=C\\C(O)=O",{"v":1.81,"d":"1.810"},3,0,8]
["S1848","Curcumin","b9","L3800-06","in 10mM DMSO","DMF","EP8.8;BP2016;IP2010;Martindale:The Extra Pharmacopoeia;CP2005","N/A","Apoptosis related,Autophagy,Epigenetic Reader Domain,Ferroptosis,HCV,HDAC,Histone Acetyltransferase,HIV,Influenza Virus,NF-κB,Nrf2","Epigenetics","Curcumin (Diferuloylmethane, Natural Yellow 3, Turmeric yellow) is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase（IC50~25 μM）and Histone deacetylase (HDAC); activates Nrf2 pathway and supresses the activation of NF-κB. Curcumin induces mitophagy, autophagy, apoptosis, and cell cycle arrest with antitumor activity. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus, hepatitis C virus, HIV and so on.",368.38,"458-37-7",{"v":73,"d":"73.00"},198.16,"<1","N/A","http://selleckchem.com/products/Curcumin.html","C21H20O6","free base","Diferuloylmethane, Natural Yellow 3, Turmeric yellow","COC1=CC(=CC=C1O)/C=C/C(O)=C/C(=O)/C=C/C2=CC(=C(O)C=C2)OC",3.573,3,3,7]
["S1849","Daidzein","c9","L3800-06","in 10mM DMSO","CFDA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","PPAR","Metabolism","Daidzein is a natural isoflavone phytoestrogen found in Leguminosae, used as a component of foods and dietary supplements. Daidzein is a soy isoflavone, which acts as a PPAR activator.",254.24,"486-66-8",{"v":51,"d":"51.00"},{"v":200.6,"d":"200.60"},"<1","N/A","http://selleckchem.com/products/Daidzein.html","C15H10O4","free base","N/A","OC1=CC=C(C=C1)C2=COC3=CC(=CC=C3C2=O)O",2.382,2,2,1]
["S1854","Bifonazole","d9","L3800-06","in 10mM DMSO","DMF,CFDA,PMDA,HMA","BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Phase 4","Fungal","Microbiology","Bifonazole (Bay h 4502,(±)-bifonazole) is a substituted imidazole antifungal agent.",310.39,"60628-96-8",{"v":62,"d":"62.00"},199.75,"<1","N/A","http://selleckchem.com/products/bifonazole.html","C22H18N2","free base","Bay h 4502,(±)-bifonazole","C1=CC=C(C=C1)C([N]2C=CN=C2)C3=CC=C(C=C3)C4=CC=CC=C4",4.637,1,0,4]
["S1855","Pefloxacin Mesylate","e9","L3800-06","in 10mM DMSO","CFDA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia;CP2005","N/A","Bacterial","Microbiology","Pefloxacin Mesylate(Pefloxacinium mesylate) is a synthetic chemotherapeutic agent and an antibacterial agent with IC50 of 6.7 nM.",429.46,"70458-95-6",{"v":14,"d":"14.00"},{"v":32.6,"d":"32.60"},{"v":67,"d":"67.00"},156.01,"http://selleckchem.com/products/pefloxacin-mesylate.html","C17H20FN3O3.CH4O3S","Mesylate","Pefloxacinium mesylate","CCN1C=C(C(O)=O)C(=O)C2=CC(=C(C=C12)N3CCN(C)CC3)F.C[S](O)(=O)=O",-1.618,2,0,3]
["S1856","Metoprolol Tartrate","f9","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Adrenergic Receptor","Neuronal Signaling","Metoprolol Tartrate (CGP 2175E) is a selective β1 receptor blocker medication, used to treat hypertension and heart failure.",684.81,"56392-17-7",{"v":100,"d":"100.00"},146.03,{"v":100,"d":"100.00"},146.03,"http://selleckchem.com/products/metoprolol-tartrate.html","2C15H25NO3.C4H6O6","Tartrate","CGP 2175E","COCCC1=CC=C(OCC(O)CNC(C)C)C=C1.COCCC2=CC=C(OCC(O)CNC(C)C)C=C2.OC(C(O)C(O)=O)C(O)=O",-3.559,6,6,21]
["S1858","Dienestrol","g9","L3800-06","in 10mM DMSO","FDA","EP7.5;USP39-NF34;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Estrogen/progestogen Receptor","Endocrinology & Hormones","Dienestrol(Restrol) is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist.",266.33,"84-17-3",{"v":53,"d":"53.00"},{"v":199,"d":"199.00"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/Dienestrol(Restrol).html","C18H18O2","Free Base","Restrol","C/C=C(C1=CC=C(O)C=C1)/C(=C/C)C2=CC=C(O)C=C2",4.692,0,2,3]
["S1859","Diethylstilbestrol","h9","L3800-06","in 10mM DMSO","FDA,DMF,CFDA","USP42-NF37;BP2019;EP9.2;CP2005;Martindale:The Extra Pharmacopoeia","Phase 2","Estrogen/progestogen Receptor","Endocrinology & Hormones","Diethylstilbestrol (Stilbestrol) is a synthetic nonsteroidal estrogen, used to prevent miscarriage and other pregnancy complications.",268.35,"56-53-1",{"v":54,"d":"54.00"},201.23,"<1","N/A","http://selleckchem.com/products/Diethylstilbestrol(Stilbestrol).html","C18H20O2","free base","Stilbestrol","CCC(/C1=CC=C(O)C=C1)=C(CC)\\C2=CC=C(O)C=C2",5.137,0,2,4]
["S1865","Diltiazem HCl","a10","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Calcium Channel","Transmembrane Transporters","Diltiazem (Tiazac, RG 83606) HCl is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions.",450.98,"33286-22-5",{"v":90,"d":"90.00"},199.57,{"v":90,"d":"90.00"},199.57,"http://selleckchem.com/products/Diltiazem-HCl(Tiazac).html","C22H26N2O4S.HCl","Hydrochloride","RG 83606 HCl","Cl.COC1=CC=C(C=C1)C2SC3=C(C=CC=C3)N(CCN(C)C)C(=O)C2OC(C)=O",3.475,4,0,7]
["S1866","Diphenhydramine HCl","b10","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia;CP2005","N/A","Histamine Receptor","Neuronal Signaling","Diphenhydramine HCl is a first-generation histamine H1 receptor antagonist, used in various allergic conditions such as rhinitis, urticaria and conjunctivitis.",291.82,"147-24-0",{"v":58,"d":"58.00"},198.75,{"v":58,"d":"58.00"},198.75,"http://selleckchem.com/products/Diphenhydramine-hydrochloride(Benadryl).html","C17H21NO.HCl","Hydrochloride","N/A","Cl.CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2",3.766,1,0,6]
["S1869","Dapoxetine HCl","c10","L3800-06","in 10mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Dapoxetine HCl (LY-210448) is a short-acting novel selective serotonin reuptake inhibitor, used for the treatment of premature ejaculation.",341.87,"129938-20-1",{"v":68,"d":"68.00"},198.91,{"v":68,"d":"68.00"},198.91,"http://selleckchem.com/products/Dapoxetine-hydrochloride(Priligy).html","C21H23NO.HCl","Hydrochloride","LY-210448","Cl.CN(C)C(CCOC1=C2C=CC=CC2=CC=C1)C3=CC=CC=C3",4.917,1,0,6]
["S1876","Valaciclovir HCl","d10","L3800-06","in 10mM DMSO","DMF,CFDA,PMDA,HMA","EP9.8;BP2019;JP17;Martindale:The Extra Pharmacopoeia","Marketed","CMV","Microbiology","Valaciclovir HCl, an aciclovir prodrug, inhibits activity of virus DNA polymerase, used to treat infections caused by herpes simplex virus (HSV) and varicella zoster virus, and for prophylaxis against cytomegalovirus (CMV).",{"v":360.8,"d":"360.80"},"124832-27-5",{"v":14,"d":"14.00"},{"v":38.8,"d":"38.80"},{"v":72,"d":"72.00"},199.56,"http://selleckchem.com/products/valaciclovir-hcl.html","C13H20N6O4.HCl","Hydrochloride","N/A","Cl.CC(C)C(N)C(=O)OCCOC[N]1C=NC2=C1N=C(N)NC2=O",-0.296,6,3,8]
["S1878","Ganciclovir (BW 759)","e10","L3800-06","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP41-NF36;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia;CP2005","Marketed","CMV","Microbiology","Ganciclovir (RS-21592, BW-759, 2'-Nor-2'-deoxyguanosine) is an antiviral drug for feline herpesvirus type-1 with IC50 of 5.2 μM in a cell-free assay.",255.23,"82410-32-0",{"v":27,"d":"27.00"},105.79,"<1","N/A","http://selleckchem.com/products/ganciclovir.html","C9H13N5O4","free base","RS-21592, BW-759, 2'-Nor-2'-deoxyguanosine","NC1=NC2=C(N=C[N]2COC(CO)CO)C(=O)N1",-1.934,4,4,5]
["S1880","Roxatidine Acetate HCl","f10","L3800-06","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia","N/A","Histamine Receptor","Neuronal Signaling","Roxatidine Acetate HCl(HOE 760) is a specific and competitive histamin H2-receptor antagonist, with IC50 of 3.2 μM, inhibits gastric acid secretion and ulcer formation.",{"v":384.9,"d":"384.90"},"93793-83-0",{"v":77,"d":"77.00"},200.05,{"v":77,"d":"77.00"},200.05,"http://selleckchem.com/products/roxatidine-acetate-hcl.html","C19H28N2O4.HCl","Hydrochloride","HOE 760","Cl.CC(=O)OCC(=O)NCCCOC1=CC=CC(=C1)CN2CCCCC2",2.148,4,1,10]
["S1881","Protionamide","g10","L3800-06","in 10mM DMSO","CFDA","Ph.Int_6th;Martindale:The Extra Pharmacopoeia","N/A","Bacterial","Microbiology","Protionamide (Prothionamide, 1321-TH) is a drug used in the treatment of tuberculosis.",180.27,"14222-60-7",{"v":36,"d":"36.00"},{"v":199.7,"d":"199.70"},"<1","N/A","http://selleckchem.com/products/protionamide-prothionamide.html","C9H12N2S","free base","Prothionamide, 1321-TH","CCCC1=NC=CC(=C1)C(N)=S",1.954,1,1,3]
["S1883","Idoxuridine","h10","L3800-06","in 10mM DMSO","FDA,DMF,CFDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Antiviral","Microbiology","Idoxuridine (NSC 39661, SKF 14287,5-Iodo-2′-deoxyuridine,5-IUdR,IdUrd) is an antiviral agent for feline herpesvirus type-1 with IC50 of 4.3 μM.",{"v":354.1,"d":"354.10"},"54-42-2",{"v":35,"d":"35.00"},98.84,"<1","N/A","http://selleckchem.com/products/idoxuridine.html","C9H11IN2O5","free base","NSC 39661, SKF 14287,5-Iodo-2′-deoxyuridine,5-IUdR,IdUrd","OCC1OC(CC1O)N2C=C(I)C(=O)NC2=O",-1.402,3,3,2]
["S1884","Sparfloxacin","a11","L3800-06","in 10mM DMSO","FDA,CFDA","Martindale:The Extra Pharmacopoeia;CP2005","Marketed","Antibiotics,Bacterial","Microbiology","Sparfloxacin (AT-4140, CI-978, PD 131501,Zagam) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity.",{"v":392.4,"d":"392.40"},"110871-86-8",{"v":9,"d":"9.00"},22.94,"<1","N/A","http://selleckchem.com/products/sparfloxacin.html","C19H22F2N4O3","free base","AT-4140, CI-978, PD 131501,Zagam","CC1CN(CC(C)N1)C2=C(F)C3=C(C(=C2F)N)C(=O)C(=CN3C4CC4)C(O)=O",-1.056,2,2,3]
["S1885","Felodipine","b11","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia;CP2005","N/A","Calcium Channel","Transmembrane Transporters","Felodipine (CGH-869) is a selective L-type Ca2+ channel blocker with IC50 of 0.15 nM.",384.25,"72509-76-3",{"v":77,"d":"77.00"},200.39,"<1","N/A","http://selleckchem.com/products/Felodipine(Plendil).html","C18H19Cl2NO4","free base","CGH-869","CCOC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2Cl)Cl)C(=O)OC)C",3.549,4,1,6]
["S1888","Deflazacort","c11","L3800-06","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","Marketed","Glucocorticoid Receptor","Endocrinology & Hormones","Deflazacort (MDL 458) is a glucocorticoid used as an anti-inflammatory and immunosuppressant.",441.52,"14484-47-0",{"v":88,"d":"88.00"},199.31,"<1","N/A","http://selleckchem.com/products/Deflazacor.html","C25H31NO6","free base","MDL 458","CC(=O)OCC(=O)C12N=C(C)OC1CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC23C",{"v":1.67,"d":"1.670"},6,1,4]
["S1890","Nizatidine","d11","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","N/A","Histamine Receptor","Neuronal Signaling","Nizatidine is a histamine H2 receptor antagonist with IC50 of 0.9 nM, also inhibits AChE with IC50 of 6.7 μM.",331.46,"76963-41-2",{"v":66,"d":"66.00"},199.12,{"v":28,"d":"28.00"},84.47,"http://selleckchem.com/products/Nizatidine(Axid).html","C12H21N5O2S2","free base","N/A","CNC(/NCCSCC1=CSC(=N1)CN(C)C)=C/[N+]([O-])=O",0.643,1,2,10]
["S1891","Carbidopa","e11","L3800-06","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","N/A","Decarboxylase","Metabolism","Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM.",226.23,"28860-95-9",{"v":4,"d":"4.00"},17.68,"<1","N/A","http://selleckchem.com/products/Carbidopa.html","C10H14N2O4","free base","N/A","CC(CC1=CC(=C(O)C=C1)O)(NN)C(O)=O",0.364,1,4,4]
["S1894","Valsartan (CGP-48933)","f11","L3800-06","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Angiotensin Receptor","GPCR & G Protein","Valsartan (CGP-48933) is a selective angiotensin II receptor antagonist, used to treat high blood pressure and congestive heart failure.",435.52,"137862-53-4",{"v":87,"d":"87.00"},199.76,"<1","N/A","http://selleckchem.com/products/Valsartan(Diovan).html","C24H29N5O3","free base","CGP-48933","CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=N[NH]N=N3)C(C(C)C)C(O)=O",4.538,5,1,10]
["S1895","Dipyridamole (NSC 515776)","g11","L3800-06","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Marketed","PDE","Metabolism","Dipyridamole (NSC-515776, Persantine) is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells.",504.63,"58-32-2",{"v":101,"d":"101.00"},200.15,"<1","N/A","http://selleckchem.com/products/Dipyridamole(Permole,-Persantine).html","C24H40N8O4","free base","Persantine,NSC-515776","OCCN(CCO)C1=NC2=C(N=C(N=C2N3CCCCC3)N(CCO)CCO)C(=N1)N4CCCCC4",2.483,4,4,12]
["S1896","Hydroxyurea (NSC-32065)","h11","L3800-06","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;BP2015","Marketed","Apoptosis related,Autophagy,DNA/RNA Synthesis,HIV","DNA Damage/DNA Repair","Hydroxyurea (NSC-32065, NCI-C04831, Hydroxycarbamide) is an antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase. Hydroxyurea activates apoptosis and autophagy. Hydroxyurea is used to treat HIV infection.",76.05,"127-07-1",{"v":15,"d":"15.00"},197.24,{"v":15,"d":"15.00"},197.24,"http://selleckchem.com/products/Hydroxyurea(Cytodrox).html","CH4N2O2","free base","NCI-C04831, Hydroxycarbamide,NSC-32065","NC(=O)NO",{"v":-1.03,"d":"-1.030"},1,2,0]
["S1897","Potassium Iodide","a2","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 4","Others","Others","Potassium Iodide is used to treat overactive thyroid and to protect the thyroid gland from the effects of radiation from inhaled or swallowed radioactive iodine.",{"v":166,"d":"166.00"},"7681-11-0",{"v":33,"d":"33.00"},{"v":198.8,"d":"198.80"},{"v":33,"d":"33.00"},{"v":198.8,"d":"198.80"},"http://selleckchem.com/products/Potassium-iodide.html","K+I-","Inorganic salt","N/A","[K+].[I-]",-3.113,0,0,0]
["S1898","Tropisetron HCl","b2","L3800-07","in 10mM DMSO","CFDA,HMA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor","Neuronal Signaling","Tropisetron HCl (ICS 205-930) is a potent and selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist, used to treat nausea and vomiting following chemotherapy.",320.81,"105826-92-4",{"v":35,"d":"35.00"},{"v":109.1,"d":"109.10"},{"v":46,"d":"46.00"},143.39,"http://selleckchem.com/products/Tropisetron-hydrochloride.html","C17H20N2O2.HCl","Hydrochloride","ICS 205-930","Cl.CN1C2CCC1CC(C2)OC(=O)C3C=NC4=CC=CC=C34",2.366,3,0,3]
["S1899","Nicotinamide (NSC 13128)","c2","L3800-07","in 10mM DMSO","DMF,CFDA,NDC,PMDA,HMA","KP Ⅹ;EP9.1;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","Phase 2/3","Sirtuin","DNA Damage/DNA Repair","Nicotinamide (Niacinamide, Vitamin PP, Nicotinic acid amide, Vitamin B3, NSC 27452,NSC 13128), a water-soluble vitamin, is an active component of coenzymes NAD and NADP, and also act as an inhibitor of sirtuins.",122.12,"98-92-0",{"v":24,"d":"24.00"},196.53,{"v":24,"d":"24.00"},196.53,"http://selleckchem.com/products/Nicotinamide(Niacinamide).html","C6H6N2O","free base","Niacinamide, Vitamin PP, Nicotinic acid amide, Vitamin B3, NSC 27452,NSC 13128","NC(=O)C1=CC=CN=C1",-0.319,2,1,1]
["S1902","Vitamin B12","d2","L3800-07","in 10mM DMSO","DMF,CFDA,NDC","USP39-NF34","N/A","Vitamin","Metabolism","Vitamin B12 (Cobalamin, Cyanocobalamin) is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.",1355.37,"68-19-9",{"v":75,"d":"75.00"},55.34,{"v":6,"d":"6.00"},4.43,"http://selleckchem.com/products/Vitamin-B12.html","C63H88CoN14O14P","free base","Cobalamin, Cyanocobalamin","CC(CNC(=O)CCC1(C)C(CC(N)=O)C2N=C1/C(=C/3N=C(/C=C/4N=C(/C(=C/5[N-]C2(C)C(C)(CC(N)=O)C5CCC(N)=O)C)C(C)(CC(N)=O)C4CCC(N)=O)C(C)(C)C3CCC(N)=O)C)O[P]([O-])(=O)OC6C(O)C(OC6CO)[N]7C=NC8=C7C=C(C)C(=C8)C.[Co++]C#N",-1.129,14,9,26]
["S1903","Diclofenac Sodium","e2","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Marketed","COX","Neuronal Signaling","Diclofenac Sodium (GP 45840) is a non-selective COX inhibitor with IC50 of 0.5 μg/ml and 0.5 μg/ml for COX-1 and -2 in intact cells, respectively, used as a nonsteroidal anti-inflammatory drug (NSAID) to relieve pain and reduce swelling in flammation.",318.13,"15307-79-6",{"v":64,"d":"64.00"},201.18,{"v":14,"d":"14.00"},44.01,"http://selleckchem.com/products/Diclofenac-sodium.html","C14H10Cl2NNaO2","Sodium Salt","GP 45840","[Na+].[O-]C(=O)CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1",2.899,0,1,4]
["S1904","Avobenzone","f2","L3800-07","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Avobenzone (Butyl methoxydibenzoylmethane, BF2AVB) is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative.",310.39,"70356-09-1",{"v":62,"d":"62.00"},199.75,"<1","N/A","http://selleckchem.com/products/Avobenzone(Parsol-1789).html","C20H22O3","free base","Butyl methoxydibenzoylmethane, BF2AVB","COC1=CC=C(C=C1)C(=O)CC(=O)C2=CC=C(C=C2)C(C)(C)C",4.538,3,0,6]
["S1905","Amlodipine","g2","L3800-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","Calcium Channel","Transmembrane Transporters","Amlodipine (UK-48340) is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.",408.88,"88150-42-9",{"v":82,"d":"82.00"},200.55,"<1","N/A","http://selleckchem.com/products/Amlodipine(Norvasc).html","C20H25ClN2O5","free base","UK-48340","CCOC(=O)C1=C(COCCN)NC(=C(C1C2=C(Cl)C=CC=C2)C(=O)OC)C",1.576,5,2,10]
["S1907","Metronidazole","h2","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia;IP2010","Marketed","Antineoplastic and Immunosuppressive Antibiotics,DNA/RNA Synthesis","DNA Damage/DNA Repair","Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa.",171.15,"443-48-1",{"v":34,"d":"34.00"},198.66,"<1","N/A","http://selleckchem.com/products/Metronidazole(Flagyl).html","C6H9N3O3","free base","N/A","CC1=NC=C([N]1CCO)[N+]([O-])=O",-0.337,1,1,3]
["S1908","Flutamide","a3","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 2","Androgen Receptor","Endocrinology & Hormones","Flutamide (SCH-13521) is an antiandrogen drug, with its active metablolite binding at androgen receptor with Ki values of 55 nM, and primarily used to treat prostate cancer.",276.21,"13311-84-7",{"v":55,"d":"55.00"},199.12,"<1","N/A","http://selleckchem.com/products/Flutamide(Eulexin).html","C11H11F3N2O3","free base","SCH-13521","CC(C)C(=O)NC1=CC(=C(C=C1)[N+]([O-])=O)C(F)(F)F",2.916,1,1,4]
["S1909","Fluvastatin (XU-62-320) Sodium","b3","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","HMG-CoA Reductase","Metabolism","Fluvastatin Sodium (Vastin,XU-62-320) inhibits HMG-CoA reductase activity with IC50 of 8 nM in a cell-free assay.",433.45,"93957-55-2",{"v":87,"d":"87.00"},200.72,{"v":1,"d":"1.00"},2.31,"http://selleckchem.com/products/Fluvastatin-Sodium(Lescol).html","C24H25FNNaO4","Sodium","Vastin,XU-62-320","[Na+].CC(C)[N]1C2=C(C=CC=C2)C(=C1\\C=C\\C(O)CC(O)CC([O-])=O)C3=CC=C(F)C=C3",{"v":2.77,"d":"2.770"},0,2,8]
["S1910","Tioconazole","c3","L3800-07","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Fungal","Microbiology","Tioconazole (UK-20349) is an antifungal medication with an average IC50 of 1.7 μM.",387.71,"65899-73-2",{"v":78,"d":"78.00"},201.18,"<1","N/A","http://selleckchem.com/products/tioconazole.html","C16H13Cl3N2OS","free base","UK-20349","ClC1=CC=C(C(C[N]2C=CN=C2)OCC3=C(Cl)SC=C3)C(=C1)Cl",4.437,2,0,6]
["S1913","Tropicamide","d3","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 2","AChR","Neuronal Signaling","Tropicamide(Ro 1-7683) is an anticholinergic and a muscarinic receptor subtype M4-preferring antagonist with IC50 of 8.0 nM.",284.35,"1508-75-4",{"v":57,"d":"57.00"},200.46,"<1","N/A","http://selleckchem.com/products/tropicamide.html","C17H20N2O2","free base","Ro 1-7683","CCN(CC1=CC=NC=C1)C(=O)C(CO)C2=CC=CC=C2",1.432,2,1,6]
["S1914","Pregnenolone","e3","L3800-07","in 10mM DMSO","DMF,CFDA,NDC","USP42-NF37","N/A","Estrogen/progestogen Receptor","Endocrinology & Hormones","Pregnenolone(3β-Hydroxy-5-pregnen-20-one) is an endogenous steroid hormone, used in the treatment of fatigue, Alzheimer’s disease, trauma and injuries.",316.48,"145-13-1",{"v":22,"d":"22.00"},69.51,"<1","N/A","http://selleckchem.com/products/pregnenolone.html","C21H32O2","free base","3β-Hydroxy-5-pregnen-20-one","CC(=O)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C",3.624,1,1,1]
["S1915","Sulfamethoxazole","f3","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia;CP2005","N/A","Antibiotics,Bacterial","Microbiology","Sulfamethoxazole(Ro 4-2130) is a sulfonamide bacteriostatic antibiotic with an IC50 of 2.7 μM.",253.28,"723-46-6",{"v":51,"d":"51.00"},201.36,"<1","N/A","http://selleckchem.com/products/Sulfamethoxazole.html","C10H11N3O3S","free base","Ro 4-2130","CC1=CC(=NO1)N[S](=O)(=O)C2=CC=C(N)C=C2",0.709,4,2,3]
["S1916","Sulfisoxazole","g3","L3800-07","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;KP Ⅹ;JP17","N/A","Bacterial","Microbiology","Sulfisoxazole (NU-445) is a sulfonamide antibacterial with an oxazole substituent.",{"v":267.3,"d":"267.30"},"127-69-5",{"v":53,"d":"53.00"},198.28,"<1","N/A","http://selleckchem.com/products/Sulfisoxazole.html","C11H13N3O3S","free base","NU-445","CC1=NOC(=C1C)N[S](=O)(=O)C2=CC=C(N)C=C2",0.918,4,2,3]
["S1917","Crystal Violet","h3","L3800-07","in 10mM DMSO","N/A","USP42-NF37;BP2019;EP9.2;IP2010","N/A","Dyes","Others","Crystal violet(Gentian Violet) is a triarylmethane dye.",407.98,"548-62-9",{"v":82,"d":"82.00"},200.99,{"v":14,"d":"14.00"},34.32,"http://selleckchem.com/products/Crystal-violet.html","C25H30ClN3","quaternary-N chloride salt","Gentian Violet","[Cl-].CN(C)C1=CC=C(C=C1)C(C2=CC=C(C=C2)N(C)C)=C3C=CC(C=C3)=[N+](C)C",{"v":2.25,"d":"2.250"},0,0,4]
["S1920","Haloperidol","a4","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","Dopamine Receptor","Neuronal Signaling","Haloperidol (Haldol) is an antipsychotic and butyrophenone.",375.86,"52-86-8",{"v":75,"d":"75.00"},199.54,"<1","N/A","http://selleckchem.com/products/Haloperidol(Haldol).html","C21H23ClFNO2","free base","N/A","OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C3=CC=C(Cl)C=C3",3.887,1,0,6]
["S1921","Phenindione","b4","L3800-07","in 10mM DMSO","FDA","BP2019;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","Vitamin","Metabolism","Phenindione (Rectadione, phenylindandione) is an anticoagulant which functions as a Vitamin K antagonist.",222.24,"83-12-5",{"v":44,"d":"44.00"},197.98,"<1","N/A","http://selleckchem.com/products/Phenindione(Rectadione).html","C15H10O2","free base","Rectadione, phenylindandione","O=C1C(C2=CC=CC=C2)C(=O)C3=CC=CC=C13",2.819,2,0,1]
["S1928","Alibendol","c4","L3800-07","in 10mM DMSO","N/A","Martindale the Extra Pharmacopoei","N/A","Others","Others","Alibendol (EB 1856) is an antispasmodic,choleretic, and cholekinetic.",251.28,"26750-81-2",{"v":50,"d":"50.00"},198.98,"<1","N/A","http://selleckchem.com/products/alibendol.html","C13H17NO4","free base","EB 1856","COC1=CC(=CC(=C1O)C(=O)NCCO)CC=C",1.248,2,3,6]
["S1933","Triamcinolone","d4","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP40-NF35;BP2015;JP16;Martindale:The Extra Pharmacopoeia","Marketed","Glucocorticoid Receptor","Endocrinology & Hormones","Triamcinolone is a glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated.",394.43,"124-94-7",{"v":78,"d":"78.00"},197.75,"<1","N/A","http://selleckchem.com/products/Triamcinolone(Aristocort).html","C21H27FO6","free base","N/A","CC12CC(O)C3(F)C(CCC4=CC(=O)C=CC34C)C1CC(O)C2(O)C(=O)CO",0.422,2,3,2]
["S1934","Nystatin (Fungicidin)","e4","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","EP9.2;Ph.Int_6th;JP17;BP2017;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics for Mammalian Cell Culture,Fungal","Microbiology","Nystatin(Fungicidin), which belongs to the polyene group of antimycotics, is frequently used as a topical agent in the treatment of oro-pharyngeal candidosis.",1056.24,"62997-67-5",{"v":19,"d":"19.00"},17.99,"<1","N/A","http://selleckchem.com/products/Nystatin(Mycostatin).html","C53H85NO20","free base","Fungicidin","CC1OC(=O)CC(O)CC(O)CC(O)CCC(O)C(O)CC2(O)CC(O)C(C(CC(OC3OC(C)C(O)C(N)C3O)/C=C/C=C/C=C/C=C/CC/C=C/C=C/C(C)C(O)C1C)O2)C(O)=O",-2.265,8,11,5]
["S1937","Isoniazid","f4","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Fatty Acid Synthase","Metabolism","Isoniazid is a prodrug that blocks the action of fatty acid synthase by interacting with KatG , used for the prevention and treatment of tuberculosis.",137.14,"54-85-3",{"v":27,"d":"27.00"},196.88,{"v":27,"d":"27.00"},196.88,"http://selleckchem.com/products/Isoniazid(Tubizid).html","C6H7N3O","free base","N/A","NNC(=O)C1=CC=NC=C1",-0.811,2,2,1]
["S1940","Levofloxacin","g4","L3800-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.8;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Topoisomerase","DNA Damage/DNA Repair","Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections.",361.37,"100986-85-4",{"v":24,"d":"24.00"},66.41,{"v":11,"d":"11.00"},30.44,"http://selleckchem.com/products/levofloxacin-levaquin.html","C18H20FN3O4","Free Base","Fluoroquinolone","CC1COC2=C(N3CCN(C)CC3)C(=CC4=C2N1C=C(C(O)=O)C4=O)F",-1.374,3,0,2]
["S1941","Enalapril Maleate","h4","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia;CP2005","Marketed","ACE,RAAS","Endocrinology & Hormones","Enalapril (MK-421) Maleate is an angiotensin-converting enzyme (ACE) inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure.",492.52,"76095-16-4",{"v":99,"d":"99.00"},201.01,"<1","N/A","http://selleckchem.com/products/Enalapril-maleate(Vasotec).html","C20H28N2O5.C4H4O4","Maleate","MK-421 Maleate","CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(O)=O.OC(=O)\\C=C/C(O)=O",-0.502,6,1,12]
["S1949","Menadione (NSC 4170)","a5","L3800-07","in 10mM DMSO","FDA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Phase 2","CDK,DNA/RNA Synthesis,phosphatase","Metabolism","Menadione (NSC 4170, Vitamin K3), a fat-soluble compound, is an inhibitor of Cdc25 phosphatase and mitochondrial DNA polymerase γ (pol γ), used as a nutritional supplement.",172.18,"58-27-5",{"v":34,"d":"34.00"},197.47,"<1","N/A","http://selleckchem.com/products/Menadione.html","C11H8O2","free base","Vitamin K3,NSC 4170","CC1=CC(=O)C2=CC=CC=C2C1=O",2.204,2,0,0]
["S1950","Metformin HCl","b5","L3800-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia;CP2005","Marketed","Autophagy,Carbohydrate Metabolism,JNK,Mitophagy,p38 MAPK","Metabolism","Metformin HCl (1,1-Dimethylbiguanide HCl) decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis). Metformin promotes mitophagy in mononuclear cells. Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153.",165.62,"1115-70-4",{"v":33,"d":"33.00"},199.25,{"v":33,"d":"33.00"},199.25,"http://selleckchem.com/products/Metformin-hydrochloride(Glucophage).html","C4H11N5.HCl","Hydrochloride","1,1-Dimethylbiguanide HCl","Cl.CN(C)C(=N)NC(N)=N",{"v":-0.36,"d":"-0.360"},0,2,3]
["S1952","Methoxsalen","c5","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","P450 (e.g. CYP17)","Metabolism","Methoxsalen (Xanthotoxin, NCI-C55903) is a naturally occurring photoactive substance found in the seeds of the Ammi majus (Umbelliferae) plant, used in the diagnosis and treatment of psoriasis; A CYP2A5/6 inhibitor.",216.19,"298-81-7",{"v":43,"d":"43.00"},{"v":198.9,"d":"198.90"},"<1","N/A","http://selleckchem.com/products/Methoxsalen(Oxsoralen).html","C12H8O4","free base","Xanthotoxin, NCI-C55903","COC1=C2OC=CC2=CC3=C1OC(=O)C=C3",2.187,4,0,1]
["S1956","Miconazole Nitrate","d5","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.7;BP2019;KP Ⅹ;Ph.Int_6th ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Fungal","Microbiology","Miconazole (NSC 169434) Nitrate is an imidazole antifungal agent by inhibiting ergosterol biosynthesis and inducing ROS, used to treat vaginal yeast infections.",479.14,"22832-87-7",{"v":96,"d":"96.00"},200.36,"<1","N/A","http://selleckchem.com/products/Miconazole-nitrate.html","C18H14Cl4N2O.HNO3","Nitrate","NSC 169434 Nitrate","O[N+]([O-])=O.ClC1=CC=C(COC(C[N]2C=CN=C2)C3=CC=C(Cl)C=C3Cl)C(=C1)Cl",4.387,2,0,6]
["S1957","Sulfamethizole","e5","L3800-07","in 10mM DMSO","FDA,DMF","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","N/A","Bacterial","Microbiology","Sulfamethizole is a sulfathiazole antibacterial agent.",270.33,"144-82-1",{"v":54,"d":"54.00"},199.76,"<1","N/A","http://selleckchem.com/products/Sulfamethizole(Proklar).html","C9H10N4O2S2","free base","N/A","CC1=NN=C(N[S](=O)(=O)C2=CC=C(N)C=C2)S1",0.305,4,2,3]
["S1958","Sulbactam","f5","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Anti-infection","Microbiology","Sulbactam(CP45899) is a beta-lactamase inhibitor with an average IC50 of 0.8 μM.",233.24,"68373-14-8",{"v":47,"d":"47.00"},201.51,{"v":47,"d":"47.00"},201.51,"http://selleckchem.com/products/sulbactam.html","C8H11NO5S","free base","CP45899","CC1(C)C(N2C(CC2=O)[S]1(=O)=O)C(O)=O",-0.671,4,0,1]
["S1959","Tolfenamic Acid","g5","L3800-07","in 10mM DMSO","DMF,CFDA,HMA","EP9.8;BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia","N/A","COX","Neuronal Signaling","Tolfenamic Acid(Clotam) is a COX-2 inhibitor with IC50 of 0.2 μM.",{"v":261.7,"d":"261.70"},"13710-19-5",{"v":52,"d":"52.00"},{"v":198.7,"d":"198.70"},"<1","N/A","http://selleckchem.com/products/tolfenamic-acid.html","C14H12ClNO2","free base","Clotam","CC1=C(Cl)C=CC=C1NC2=C(C=CC=C2)C(O)=O",{"v":4.16,"d":"4.160"},1,1,3]
["S1960","Pranoprofen","h5","L3800-07","in 10mM DMSO","CFDA,PMDA","KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","COX,PGES","Neuronal Signaling","Pranoprofen (Pyranoprofen,Pranopulin) is a non-steroidal COX inhibitor, used as an anti-inflammatory drug in ophthalmology.",255.27,"52549-17-4",{"v":51,"d":"51.00"},199.79,"<1","N/A","http://selleckchem.com/products/pranoprofen.html","C15H13NO3","free base","Pyranoprofen,Pranopulin","CC(C(O)=O)C1=CC2=C(OC3=NC=CC=C3C2)C=C1",{"v":3.05,"d":"3.050"},3,0,2]
["S1962","Sulphadimethoxine","a6","L3800-07","in 10mM DMSO","DMF","EP10.4, USP43-NF38","N/A","Anti-infection","Microbiology","Sulphadimethoxine is a non-reducing glucuronide.",310.33,"122-11-2",{"v":62,"d":"62.00"},199.79,"<1","N/A","http://selleckchem.com/products/sulphadimethoxine.html","C12H14N4O4S","free base","N/A","COC1=CC(=NC(=N1)OC)N[S](=O)(=O)C2=CC=C(N)C=C2",1.358,6,2,5]
["S1964","Rimantadine","b6","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","N/A","Influenza Virus","Microbiology","Rimantadine (Flumadine) is an anti-influenza virus drug for T. brucei with IC50 of 7 μM.",{"v":179.3,"d":"179.30"},"13392-28-4",{"v":33,"d":"33.00"},184.05,{"v":33,"d":"33.00"},184.05,"http://selleckchem.com/products/rimantadine-flumadine.html","C12H21N","free base","N/A","CC(N)[C]12C[CH]3[CH2]C([CH2][CH](C3)C1)C2",2.204,0,1,1]
["S1965","Primidone","c6","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.3;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Phase 2","Sodium Channel","Transmembrane Transporters","Primidone (NCI-C56360) is an anticonvulsant of the pyrimidinedione class.",218.25,"125-33-7",{"v":44,"d":"44.00"},{"v":201.6,"d":"201.60"},"<1","N/A","http://selleckchem.com/products/Primidone(Mysoline).html","C12H14N2O2","free base","NCI-C56360","CCC1(C(=O)NCNC1=O)C2=CC=CC=C2",0.931,2,2,2]
["S1969","Nefiracetam","d6","L3800-07","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia","N/A","GABA Receptor","Neuronal Signaling","Nefiracetam (DZL 221) is a GABAergic, cholinergic, and monoaminergic neuronal system enhancer for Ro 5-4864-induced convulsions. Phase 2.",{"v":246.3,"d":"246.30"},"77191-36-7",{"v":49,"d":"49.00"},198.94,{"v":5,"d":"5.00"},{"v":20.3,"d":"20.30"},"http://selleckchem.com/products/Nefiracetam(Translon).html","C14H18N2O2","free base","DZL 221","CC1=CC=CC(=C1NC(=O)CN2CCCC2=O)C",1.443,2,1,3]
["S1971","Nicorandil","e6","L3800-07","in 10mM DMSO","DMF,CFDA,PMDA,HMA","BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Potassium Channel","Transmembrane Transporters","Nicorandil (SG-75) is a potassium channel activator, and stimulates guanylate cyclase to increase formation of cyclic GMP (cGMP).",211.17,"65141-46-0",{"v":42,"d":"42.00"},198.89,{"v":17,"d":"17.00"},{"v":80.5,"d":"80.50"},"http://selleckchem.com/products/Nicorandil(Ikorel).html","C8H9N3O4","free base","SG-75","[O-][N+](=O)OCCNC(=O)C1=CC=CN=C1",1.758,3,1,5]
["S1972","Tamoxifen (ICI 46474) Citrate","f6","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,Estrogen/progestogen Receptor,HSP (HSP90)","Endocrinology & Hormones","Tamoxifen Citrate (Istubal,ICI 46474 Citrate) is a selective estrogen receptor modulator (SERM). Tamoxifen Citrate is also a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen induces apoptosis and autophagy.",563.64,"54965-24-1",{"v":100,"d":"100.00"},177.42,"<1","N/A","http://selleckchem.com/products/Tamoxifen-Citrate(Nolvadex).html","C26H29NO.C6H8O7","Citrate","Istubal,ICI 46474 Citrate","CC/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(OCCN(C)C)C=C3.OC(=O)CC(O)(CC(O)=O)C(O)=O",1.966,4,0,13]
["S1973","Cyclocytidine HCl","g6","L3800-07","in 10mM DMSO","CFDA","N/A","N/A","DNA/RNA Synthesis","DNA Damage/DNA Repair","Cyclocytidine (NSC 145668) is the prodrug of cytarabine, which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia.",261.66,"10212-25-6",{"v":10,"d":"10.00"},38.22,{"v":44,"d":"44.00"},168.16,"http://selleckchem.com/products/cyclocytidine-hcl.html","C9H12ClN3O4","Hydrochloride","NSC 145668 HCl","Cl.OCC1OC2C(OC3=NC(=N)C=CN23)C1O",-1.395,3,2,1]
["S1974","Meglumine","h6","L3800-07","in 10mM DMSO","N/A","USP42-NF37;EP9.8;KP Ⅹ;JP17;Ph.Int_6th;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Meglumine(Meglumin,Methylglucamine) is an amino sugar derived from sorbitol for THP-1 cells with IC50 of 22 μg/mL.",195.21,"6284-40-8",{"v":39,"d":"39.00"},199.78,{"v":39,"d":"39.00"},199.78,"http://selleckchem.com/products/meglumine.html","C7H17NO5","free base","Meglumin,Methylglucamine","CNCC(O)C(O)C(O)C(O)CO",-2.798,0,6,6]
["S1975","Aripiprazole","a7","L3800-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor","Neuronal Signaling","Aripiprazole (OPC-14597) is a novel atypical antipsychotic drug that is reported to be a high-affinity 5-HT receptor partial agonist.",448.39,"129722-12-9",{"v":90,"d":"90.00"},200.72,"<1","N/A","http://selleckchem.com/products/aripiprazole-abilify.html","C23H27Cl2N3O2","free base","OPC-14597","ClC1=CC=CC(=C1Cl)N2CCN(CCCCOC3=CC=C4CCC(=O)NC4=C3)CC2",4.998,2,1,7]
["S1978","Methscopolamine","b7","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37","N/A","AChR","Neuronal Signaling","Methscopolamine is a muscarinic acetylcholine receptor blocker.",398.29,"155-41-9",{"v":79,"d":"79.00"},198.35,{"v":67,"d":"67.00"},168.22,"http://selleckchem.com/products/Methscopolamine-bromide(Pamine).html","C18H24BrNO4","quaternary-N bromide salt","N/A","[Br-].C[N+]1(C)C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",-2.949,3,1,5]
["S1979","Amiodarone (NSC 85442) HCl","c7","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,Potassium Channel","Transmembrane Transporters","Amiodarone (NSC 85442,Amiodar,Amiodarone hydrochloride,Nexterone) HCl is a sodium/potassium-ATPase inhibitor and an autophagy activator, used to treat various types of cardiac dysrhythmias.",681.77,"19774-82-4",{"v":23,"d":"23.00"},33.74,"<1","N/A","http://selleckchem.com/products/amiodarone-hcl.html","C25H29I2NO3.HCl","Hydrochloride","Amiodar,Amiodarone hydrochloride,Nexterone","Cl.CCCCC1=C(C(=O)C2=CC(=C(OCCN(CC)CC)C(=C2)I)I)C3=C(O1)C=CC=C3",{"v":7.62,"d":"7.620"},3,0,11]
["S1983","Adenine HCl","d7","L3800-07","in 10mM DMSO","DMF,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP16;Martindale:The Extra Pharmacopoeia","N/A","DNA/RNA Synthesis","DNA Damage/DNA Repair","Adenine HCl(6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.",171.59,"2922-28-3",{"v":8,"d":"8.00"},46.62,{"v":4,"d":"4.00"},23.31,"http://selleckchem.com/products/adenine-hydrochloride.html","C5H5N5.HCl","Hydrochloride","6-Aminopurine hydrochloride","Cl.NC1=NC=NC2=C1N=C[NH]2",{"v":-0.06,"d":"-0.060"},3,2,0]
["S1987","Mometasone furoate","e7","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.5;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Glucocorticoid Receptor","Endocrinology & Hormones","Mometasone Furoate (SCH-32088,mometasone 17-furoate) is a glucocorticoid receptor agonist, used topically to reduce inflammation of the skin or in the airways.",521.43,"83919-23-7",{"v":6,"d":"6.00"},11.51,"<1","N/A","http://selleckchem.com/products/mometasone-furoate.html","C27H30Cl2O6","Furoate","SCH-32088,mometasone 17-furoate","CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(Cl)C(O)CC2(C)C1(OC(=O)C5=CC=CO5)C(=O)CCl",4.616,5,1,5]
["S1988","Propylthiouracil","f7","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Peroxidases","Metabolism","Propylthiouracil (NSC 6498, NSC 70461) is a thyroperoxidase and 5'-deiodinase inhibitor, used to treat hyperthyroidism.",170.23,"51-52-5",{"v":34,"d":"34.00"},199.73,"<1","N/A","http://selleckchem.com/products/Propylthiouracil.html","C7H10N2OS","free base","NSC 6498, NSC 70461","CCCC1=CC(=O)NC(=S)N1",1.575,1,2,2]
["S1990","Capsaicin(Vanilloid)","g7","L3800-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Phase 3","TRP Channel","Transmembrane Transporters","Capsaicin (Qutenza, Vanilloid) is an active component of chili peppers, which are plants belonging to the genus Capsicum.Capsaici is a TRPV1 agonist with an EC50 of 0.29 μM in HEK293 cells.",305.41,"404-86-4",{"v":61,"d":"61.00"},199.73,"<1","N/A","http://selleckchem.com/products/capsaicin.html","C18H27NO3","free base","Qutenza, Vanilloid","COC1=C(O)C=CC(=C1)CNC(=O)CCCC\\C=C\\C(C)C",{"v":3.91,"d":"3.910"},2,2,9]
["S1992","Fluticasone propionate","h7","L3800-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Glucocorticoid Receptor","Endocrinology & Hormones","Fluticasone Propionate (CCI-187881) is a synthetic glucocorticoid, used to treat non-allergic and allergic rhinitis.",500.57,"80474-14-2",{"v":100,"d":"100.00"},199.77,"<1","N/A","http://selleckchem.com/products/fluticasone-propionate-Flonase-Veramyst.html","C25H31F3O5S","free base","CCI-187881","CCC(=O)OC1(C(C)CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)SCF",4.086,4,1,6]
["S1994","Lacidipine","a8","L3800-07","in 10mM DMSO","DMF,CFDA,HMA","BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia","Marketed","Calcium Channel","Transmembrane Transporters","Lacidipine (GX-1048, GR-43659X, SN-305) is a L-type calcium channel blocker, used for treating high blood pressure.",455.54,"103890-78-4",{"v":91,"d":"91.00"},199.76,"<1","N/A","http://selleckchem.com/products/lacidipine-lacipil-motens.html","C26H33NO6","free base","GX-1048, GR-43659X, SN-305","CCOC(=O)C1=C(C)NC(=C(C1C2=C(C=CC=C2)\\C=C\\C(=O)OC(C)(C)C)C(=O)OCC)C",3.824,6,1,11]
["S2001","Elvitegravir (JTK-303)","b8","L3800-07","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Phase 3","Integrase","Microbiology","Elvitegravir (GS-9137,JTK-303,D06677) is an HIV integrase inhibitor for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM in cell-free assays, respectively.",447.88,"697761-98-1",{"v":89,"d":"89.00"},198.71,"<1","N/A","http://selleckchem.com/products/Elvitegravir.html","C23H23ClFNO5","free base","GS-9137,JTK-303,D06677","COC1=CC2=C(C=C1CC3=C(F)C(=CC=C3)Cl)C(=O)C(=CN2C(CO)C(C)C)C(O)=O",4.665,3,1,7]
["S2003","Maraviroc (UK-427857)","c8","L3800-07","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","CCR,HIV","Microbiology","Maraviroc (Celsentri,UK-427857) is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM in cell-free assays, respectively. Maraviroc is used in the treatment of HIV infection.",513.67,"376348-65-1",{"v":100,"d":"100.00"},194.68,"<1","N/A","http://selleckchem.com/products/Maraviroc.html","C29H41F2N5O","free base","Celsentri,UK-427857","CC(C)C1=NN=C(C)[N]1C2CC3CCC(C2)N3CCC(NC(=O)C4CCC(F)(F)CC4)C5=CC=CC=C5",3.921,3,1,8]
["S2005","Raltegravir (MK-0518)","d8","L3800-07","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","USP42-NF37;EP9.4;BP2019;Martindale:The Extra Pharmacopoeia","Marketed","Integrase","Microbiology","Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM in cell-free assays, respectively. It shows greater than 1000-fold selectivity for HIV-1 IN over several related Mg2+-dependent enzyme such as HCV polymerase, HIV reverse transcriptase, HIV RNaseH and human α-, β-, γ-polymerases.",444.42,"518048-05-0",{"v":88,"d":"88.00"},198.01,"<1","N/A","http://selleckchem.com/products/Raltegravir-(MK-0518).html","C20H21FN6O5","free base","MK-0518","CN1C(=O)C(=C(N=C1C(C)(C)NC(=O)C2=NN=C(C)O2)C(=O)NCC3=CC=C(F)C=C3)O",-0.291,7,3,6]
["S2006","Pyrimethamine","e8","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;EP9.7;BP2019;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","N/A","DHFR","Metabolism","Pyrimethamine(RP 4753) is a dihydrofolate reductase (DHFR) inhibitor, used as an antimalarial drug.",248.71,"58-14-0",{"v":10,"d":"10.00"},40.21,"<1","N/A","http://selleckchem.com/products/Pyrimethamine.html","C12H13ClN4","free base","RP 4753","CCC1=NC(=NC(=C1C2=CC=C(Cl)C=C2)N)N",{"v":2.75,"d":"2.750"},2,2,2]
["S2007","Sulindac","f8","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Phase 3","COX","Neuronal Signaling","Sulindac(MK-231) is a non-steroidal COX inhibitor, which potently inhibits prostaglandin synthesis, used in the treatment of acute or chronic inflammatory conditions.",356.41,"38194-50-2",{"v":71,"d":"71.00"},199.21,"<1","N/A","http://selleckchem.com/products/Sulindac(Clinoril).html","C20H17FO3S","free base","MK-231","CC1=C(CC(O)=O)C2=C(C=CC(=C2)F)\\C1=C/C3=CC=C(C=C3)[S](C)=O",3.639,2,0,4]
["S2011","Pramipexole 2HCl Monohydrate","g8","L3800-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Dopamine Receptor","Neuronal Signaling","Pramipexole 2HCl Monohydrate is a novel non-ergoline dopamine (DA) agonist, used to treat Parkinson's disease.",302.26,"191217-81-9",{"v":41,"d":"41.00"},135.64,{"v":60,"d":"60.00"},{"v":198.5,"d":"198.50"},"http://selleckchem.com/products/Pramipexole-dihydrochloride-monohydrate.html","C10H17N3S.2HCl.H2O","Dihydrochloride monohydrate","N/A","O.Cl.Cl.CCCNC1CCC2=C(C1)SC(=N2)N",{"v":1.94,"d":"1.940"},1,2,3]
["S2015","Suplatast Tosylate","h8","L3800-07","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Interleukins","Immunology & Inflammation","Suplatast Tosylate (IPD-1151T, Suplatast Tosilate) is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM.",499.64,"94055-76-2",{"v":100,"d":"100.00"},200.14,{"v":100,"d":"100.00"},200.14,"http://selleckchem.com/products/suplatast-tosilate.html","C23H33NO7S2","Tosylate","IPD-1151T, Suplatast Tosilate","CCOCC(O)COC1=CC=C(NC(=O)CC[S+](C)C)C=C1.CC2=CC=C(C=C2)[S]([O-])(=O)=O",0.877,3,2,11]
["S2016","Mirtazapine","a9","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor","Neuronal Signaling","Mirtazapine (Org3770,6-Azamianserin) is an adrenergic and seroton receptor antagonist, used to treat depression.",265.35,"85650-52-8",{"v":53,"d":"53.00"},199.74,"<1","N/A","http://selleckchem.com/products/mirtazapine-remeron-avanza.html","C17H19N3","free base","Org3770,6-Azamianserin","CN1CCN2C(C1)C3=C(CC4=C2N=CC=C4)C=CC=C3",3.094,1,0,0]
["S2017","Benidipine HCl","b9","L3800-07","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","Calcium Channel","Transmembrane Transporters","Benidipine HCl (KW-3049,(±)- Benidipine) is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker.",542.02,"91599-74-5",{"v":8,"d":"8.00"},14.76,"<1","N/A","http://selleckchem.com/products/benidipine-hydrochloride.html","C28H31N3O6.HCl","Hydrochloride","KW-3049,(±)- Benidipine","Cl.COC(=O)C1=C(C)NC(=C(C1C2=CC(=CC=C2)[N+]([O-])=O)C(=O)OC3CCCN(C3)CC4=CC=CC=C4)C",{"v":4.36,"d":"4.360"},4,1,9]
["S2018","ENMD-2076 L-(+)-Tartaric acid","c9","L3800-07","in 10mM DMSO","N/A","N/A","Phase 2","Aurora Kinase,FLT3,VEGFR","Angiogenesis","ENMD-2076 L-(+)-Tartaric acid is the tartaric acid of ENMD-2076, selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold more selective for Aurora A than Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα. Phase 2.",525.56,"1291074-87-7",{"v":100,"d":"100.00"},190.27,"<1","N/A","http://selleckchem.com/products/enmd-2076-l-tartaric-acid.html","C25H31N7O6","free base","N/A","CN1CCN(CC1)C2=NC(=NC(=C2)NC3=N[NH]C(=C3)C)\\C=C\\C4=CC=CC=C4.OC(C(O)C(O)=O)C(O)=O",-0.683,5,4,8]
["S2020","Formoterol Hemifumarate","d9","L3800-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Formoterol Hemifumarate (Eformoterol, CGP 25827A, NSC 299587, YM 08316,Formoterol fumarate) is a potent, selective and long-acting β2-adrenoceptor agonist used in the management of asthma and chronic obstructive pulmonary disease(COPD).",{"v":402.4,"d":"402.40"},"43229-80-7",{"v":80,"d":"80.00"},198.81,"<1","N/A","http://selleckchem.com/products/formoterol-hemifumarate.html","C19H24N2O4.1/2C4H4O4","Hemifumarate","Eformoterol, CGP 25827A, NSC 299587, YM 08316,Formoterol fumarate","COC1=CC=C(CC(C)NCC(O)C2=CC=C(O)C(=C2)NC=O)C=C1.COC3=CC=C(CC(C)NCC(O)C4=CC=C(O)C(=C4)NC=O)C=C3.OC(=O)\\C=C\\C(O)=O",-1.526,6,8,18]
["S2021","Chlormezanone","e9","L3800-07","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Chlormezanone，a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.",273.74,"80-77-3",{"v":55,"d":"55.00"},200.92,"<1","N/A","http://selleckchem.com/products/Chlormezanone(Trancopal).html","C11H12ClNO3S","free base","N/A","CN1C(C2=CC=C(Cl)C=C2)[S](=O)(=O)CCC1=O",1.559,3,0,1]
["S2024","Ketotifen Fumarate","f9","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Histamine Receptor","Neuronal Signaling","Ketotifen Fumarate(HC 20511 fumarate) is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer.",{"v":425.5,"d":"425.50"},"34580-14-8",{"v":8,"d":"8.00"},{"v":18.8,"d":"18.80"},"<1","N/A","http://selleckchem.com/products/ketotifen-fumarate-zaditor.html","C19H19NOS.C4H4O4","Fumarate","HC 20511 fumarate","CN1CCC(CC1)=C2C3=C(CC(=O)C4=C2C=CS4)C=CC=C3.OC(=O)\\C=C\\C(O)=O",0.772,3,0,2]
["S2025","Urapidil HCl","g9","L3800-07","in 10mM DMSO","DMF,CFDA,PMDA,HMA","JP17;Martindale:The Extra Pharmacopoeia","Phase 4","5-HT Receptor","Neuronal Signaling","Urapidil HCl is a hydrochloride salt form of urapidil which is α1-adrenoceptor antagonist and 5-HT1A receptor agonist with pIC50 of 6.13 and 6.4 respectively.",423.94,"64887-14-5",{"v":24,"d":"24.00"},56.61,{"v":85,"d":"85.00"},{"v":200.5,"d":"200.50"},"http://selleckchem.com/products/urapidil-hydrochloride.html","C20H29N5O3.HCl","Hydrochloride","N/A","Cl.COC1=CC=CC=C1N2CCN(CCCNC3=CC(=O)N(C)C(=O)N3C)CC2",1.808,3,1,7]
["S2028","Diclazuril","h9","L3800-07","in 10mM DMSO","DMF","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Parasite","Microbiology","Diclazuril(R-64433) is an anti-coccidial drug.",407.64,"101831-37-2",{"v":16,"d":"16.00"},39.25,"<1","N/A","http://selleckchem.com/products/diclazuril.html","C17H9Cl3N4O2","free base","R-64433","ClC1=CC=C(C=C1)C(C#N)C2=C(Cl)C=C(C=C2Cl)N3N=CC(=O)NC3=O",4.191,3,1,3]
["S2029","Uridine","a10","L3800-07","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;EP9.2;BP2017;IP2010;Martindale:The Extra Pharmacopoeia","N/A","DNA/RNA Synthesis","DNA Damage/DNA Repair","Uridine (NSC 20256,β-Uridine, Uridin) is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond.",{"v":244.2,"d":"244.20"},"58-96-8",{"v":49,"d":"49.00"},200.66,{"v":49,"d":"49.00"},200.66,"http://selleckchem.com/products/uridine.html","C9H12N2O6","free base","NSC 20256,β-Uridine, Uridin","OCC1OC(C(O)C1O)N2C=CC(=O)NC2=O",-2.451,3,4,2]
["S2030","Flunarizine 2HCl","b10","L3800-07","in 10mM DMSO","DMF,CFDA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Calcium Channel","Transmembrane Transporters","Flunarizine 2HCl (KW-3149, R14950) is a dihydrochloride salt form which is a calcium channel blocker with a Ki of 68 nM.",477.42,"30484-77-6",{"v":5,"d":"5.00"},10.47,"<1","N/A","http://selleckchem.com/products/flunarizine-dihydrochloride.html","C26H26F2N2.2HCl","2HCl","KW-3149, R14950","Cl.Cl.FC1=CC=C(C=C1)C(N2CCN(CC2)C\\C=C\\C3=CC=CC=C3)C4=CC=C(F)C=C4",6.699,0,0,6]
["S2031","Fenticonazole Nitrate","c10","L3800-07","in 10mM DMSO","DMF,HMA","BP2019;EP9.2;KP Ⅹ;Martindale:The Extra Pharmacopoeia","N/A","Fungal","Microbiology","Fenticonazole Nitrate(Lomexin,REC 15-1476,Falvin) is an azole antifungal agent.",518.41,"73151-29-8",{"v":104,"d":"104.00"},200.61,"<1","N/A","http://selleckchem.com/products/fenticonazole-nitrate.html","C24H20Cl2N2OS.HNO3","Nitrate","Lomexin,REC 15-1476,Falvin","O[N+]([O-])=O.ClC1=CC=C(C(C[N]2C=CN=C2)OCC3=CC=C(SC4=CC=CC=C4)C=C3)C(=C1)Cl",5.176,2,0,8]
["S2032","Rebamipide","d10","L3800-07","in 10mM DMSO","DMF,CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","CCK receptor","GPCR & G Protein","Rebamipide (OPC-12759,Proamipide) is a cholecystokinin type 1 (CCK1) receptor inhibitor for inhibiting [125I]BH-CCK-8S with IC50 of 37.7 μM.",370.79,"90098-04-7",{"v":74,"d":"74.00"},199.57,"<1","N/A","http://selleckchem.com/products/rebamipide.html","C19H15ClN2O4","free base","OPC-12759,Proamipide","OC(=O)C(CC1=CC(=O)NC2=C1C=CC=C2)NC(=O)C3=CC=C(Cl)C=C3",2.606,3,2,5]
["S2036","Aspartame","e10","L3800-07","in 10mM DMSO","NDC","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Aspartame (SC-18862,Nutrasweet) is an artificial, non-saccharide sweetener used as a sugar substitute in some foods and beverages.",{"v":294.3,"d":"294.30"},"22839-47-0",{"v":33,"d":"33.00"},112.13,{"v":4,"d":"4.00"},13.59,"http://selleckchem.com/products/aspartame.html","C14H18N2O5","free base","SC-18862,Nutrasweet","COC(=O)C(CC1=CC=CC=C1)NC(=O)C(N)CC(O)=O",-2.455,4,2,8]
["S2037","Candesartan Cilexetil","f10","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Angiotensin Receptor","GPCR & G Protein","Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist with IC50 of 0.26 nM, used in the treatment of hypertension.",610.66,"145040-37-5",{"v":122,"d":"122.00"},199.78,"<1","N/A","http://selleckchem.com/products/Candesartan-cilexetil-Atacand.html","C33H34N6O6","free base","TCV-116","CCOC1=NC2=C([N]1CC3=CC=C(C=C3)C4=C(C=CC=C4)C5=NN=N[NH]5)C(=CC=C2)C(=O)OC(C)OC(=O)OC6CCCCC6",6.913,10,1,13]
["S2038","Phentolamine Mesylate","g10","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","SP42-NF37;IP2010","Marketed","Adrenergic Receptor","Neuronal Signaling","Phentolamine Mesylate(Phentolamine methanesulfonate) is a reversible and nonselective alpha-adrenergic receptor antagonist, used for the prevention or control of hypertensive episodes.",377.46,"65-28-1",{"v":76,"d":"76.00"},201.35,{"v":76,"d":"76.00"},201.35,"http://selleckchem.com/products/phentolamine-mesilate.html","C17H19N3O.CH4O3S","Mesylate","Phentolamine methanesulfonate","CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.C[S](O)(=O)=O",2.555,1,2,4]
["S2040","Nimesulide","h10","L3800-07","in 10mM DMSO","DMF,CFDA,HMA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Phase 3","COX","Neuronal Signaling","Nimesulide is a relatively COX-2 selective inhibitor with IC50 of 26 μM.",308.31,"51803-78-2",{"v":62,"d":"62.00"},{"v":201.1,"d":"201.10"},"<1","N/A","http://selleckchem.com/products/Nimesulide.html","C13H12N2O5S","free base","N/A","C[S](=O)(=O)NC1=C(OC2=CC=CC=C2)C=C(C=C1)[N+]([O-])=O",2.195,3,1,5]
["S2041","Dyclonine HCl","a11","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","Phase 4","Sodium Channel","Transmembrane Transporters","Dyclonine HCl(Dyclocaine HCl) is a hydrochloride salt form of dyclonine which is an oral anaesthetic, reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation.",325.87,"536-43-6",{"v":15,"d":"15.00"},46.03,{"v":6,"d":"6.00"},18.41,"http://selleckchem.com/products/dyclonine-hydrochloride.html","C18H27NO2.HCl","Hydrochloride","Dyclocaine HCl","Cl.CCCCOC1=CC=C(C=C1)C(=O)CCN2CCCCC2",4.435,2,0,8]
["S2042","Cyproterone Acetate","b11","L3800-07","in 10mM DMSO","DMF,CFDA,HMA","BP2019;EP9.2;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Androgen Receptor","Endocrinology & Hormones","Cyproterone acetate is an androgen receptor (AR) antagonist with IC50 of 7.1 nM, as well as a weak progesterone receptor agonist with weak pro-gestational and glucocorticoid activity.",416.94,"427-51-0",{"v":83,"d":"83.00"},199.07,"<1","N/A","http://selleckchem.com/products/cyproterone-acetate.html","C24H29ClO4","free base","N/A","CC(=O)OC1(CCC2C3C=C(Cl)C4=CC(=O)C5CC5C4(C)C3CCC12C)C(C)=O",3.314,4,0,3]
["S2043","Memantine HCl","c11","L3800-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","NMDAR","Neuronal Signaling","Memantine HCl is an antagonist of NMDAR. It is also a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6 with IC50 of 1.12 μM and 242.4 μM, Ki of 0.51 μM and 84.4 μM, respectively.",215.76,"41100-52-1",{"v":43,"d":"43.00"},{"v":199.3,"d":"199.30"},{"v":30,"d":"30.00"},139.04,"http://selleckchem.com/products/memantine-hydrochloride-namenda.html","C12H21N.HCl","Hydrochloride","N/A","Cl.CC12C[CH]3CC(C)([CH2]1)C[C](N)(C3)C2",2.289,0,1,0]
["S2044","Cyproheptadine HCl","d11","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Histamine Receptor","Neuronal Signaling","Cyproheptadine HCl(Periactin) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist.",323.86,"969-33-5",{"v":65,"d":"65.00"},{"v":200.7,"d":"200.70"},"<1","N/A","http://selleckchem.com/products/cyproheptadine-hydrochloride-periactin.html","C21H21N.HCl","Hydrochloride","Periactin","Cl.CN1CCC(CC1)=C2C3=C(C=CC=C3)C=CC4=C2C=CC=C4",4.744,0,0,0]
["S2045","Doxifluridine","e11","L3800-07","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia","N/A","Phosphorylase","Metabolism","Doxifluridine (5'-DFUR, AMC 0101) is an oral prodrug that is converted to the cytotoxic agent 5-fluorouracil (5-FU).",246.19,"3094-09-5",{"v":49,"d":"49.00"},199.03,{"v":49,"d":"49.00"},199.03,"http://selleckchem.com/products/doxifluridine.html","C9H11FN2O5","free base","5'-DFUR, AMC 0101","CC1OC(C(O)C1O)N2C=C(F)C(=O)NC2=O",-1.653,3,3,1]
["S2046","Pioglitazone HCl","f11","L3800-07","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Ferroptosis,P450 (e.g. CYP17),PPAR","Metabolism","Pioglitazone HCl (AD-4833, U-72107E) is an inhibitor of cytochrome P450 (CYP)2C8 and CYP3A4 enzymes. Pioglitazone HCl inhibits CYP2C8, CYP3A4 and CYP2C9 with Ki of 1.7 μM, 11.8 μM and 32.1 μM, respectively. Pioglitazone HCl is also a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist with EC50 of 0.93 μM and 0.99 μM for human PPARγ and mouse PPARγ, respectively. Pioglitazone HCl inhibits mitochondrial iron uptake, lipid peroxidation, and subsequent ferroptosis.",{"v":392.9,"d":"392.90"},"112529-15-4",{"v":79,"d":"79.00"},201.07,"<1","N/A","http://selleckchem.com/products/pioglitazone-hydrochloride-actos.html","C19H20N2O3S.HCl","Hydrochloride","AD-4833, U-72107E","Cl.CCC1=CC=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)N=C1",4.289,4,1,7]
["S2051","Captopril","g11","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","ACE,RAAS","Endocrinology & Hormones","Captopril (SQ 14225,Capoten) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.",217.29,"62571-86-2",{"v":43,"d":"43.00"},197.89,{"v":2,"d":"2.00"},{"v":9.2,"d":"9.20"},"http://selleckchem.com/products/captopril-capoten.html","C9H15NO3S","free base","SQ 14225,Capoten","CC(CS)C(=O)N1CCCC1C(O)=O",0.667,2,0,3]
["S2052","Oxytetracycline Dihydrate","h11","L3800-07","in 10mM DMSO","FDA,DMF,CFDA,PMDA","EP9.2;JP17;BP2017 ;Ph.Int_5th;Martindale:The Extra Pharmacopoeia","Phase 3","Antibiotics,Bacterial","Microbiology","Oxytetracycline Dihydrate is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.",496.46,"6153-64-6",{"v":5,"d":"5.00"},10.07,"<1","N/A","http://selleckchem.com/products/oxytetracycline-dihydrate.html","C22H24N2O9.2H2O","Dihydrate","N/A","O.O.CN(C)C1C2C(O)C3C(=C(O)C2(O)C(=O)C(=C1O)C(N)=O)C(=O)C4=C(O)C=CC=C4C3(C)O",-2.309,3,5,2]
["S2053","Cytidine","a2","L3800-08","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia","N/A","Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA.",243.22,"65-46-3",{"v":49,"d":"49.00"},201.46,{"v":49,"d":"49.00"},201.46,"http://selleckchem.com/products/cytidine.html","C9H13N3O5","free base","N/A","NC1=NC(=O)N(C=C1)C2OC(CO)C(O)C2O",-2.396,3,4,2]
["S2054","Orphenadrine Citrate","b2","L3800-08","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","AChR","Neuronal Signaling","Orphenadrine Citrate is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.",{"v":461.5,"d":"461.50"},"4682-36-4",{"v":92,"d":"92.00"},199.35,"<1","N/A","http://selleckchem.com/products/orphenadrine-citrate-norflex.html","C18H23NO.C6H8O7","Citrate","N/A","CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2C.OC(=O)CC(O)(CC(O)=O)C(O)=O",-0.483,4,0,11]
["S2055","Gimeracil","c2","L3800-08","in 10mM DMSO","EMA,CFDA","N/A","Marketed","Dehydrogenase","Metabolism","Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase, which inhibits the early step in homologous recombination for double strand breaks repair.",145.54,"103766-25-2",{"v":29,"d":"29.00"},199.26,"<1","N/A","http://selleckchem.com/products/gimeracil.html","C5H4ClNO2","free base","N/A","OC1=CC(=O)NC=C1Cl",-0.493,1,2,0]
["S2057","Cyclophosphamide (NSC-26271) Monohydrate","d2","L3800-08","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","DNA alkylator","DNA Damage/DNA Repair","Cyclophosphamide (NSC-26271, Cytoxan) Monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA, shown to crosslink DNA, causing strand breakage and inducing mutations.",{"v":279.1,"d":"279.10"},"6055-19-2",{"v":55,"d":"55.00"},197.06,{"v":7,"d":"7.00"},25.08,"http://selleckchem.com/products/cyclophosphamide-monohydrate.html","C7H15Cl2N2O2P.H2O","Monohydrate","Cytoxan Monohydrate","O.ClCCN(CCCl)[P]1(=O)NCCCO1",-0.063,2,1,5]
["S2058","Tolnaftate","e2","L3800-08","in 10mM DMSO","DMF,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","N/A","Fungal","Microbiology","Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.",307.41,"2398-96-1",{"v":62,"d":"62.00"},201.69,"<1","N/A","http://selleckchem.com/products/tolnaftate.html","C19H17NOS","free base","N/A","CN(C(=S)OC1=CC=C2C=CC=CC2=C1)C3=CC(=CC=C3)C",6.289,1,0,4]
["S2059","Terazosin HCl Dihydrate","f2","L3800-08","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Terazosin HCl is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH).",459.92,"70024-40-7",{"v":26,"d":"26.00"},56.53,"<1","N/A","http://selleckchem.com/products/terazosin-hydrochloride-hytrin.html","C19H25N5O4.HCl.2H2O","HCl & Dihydrate","N/A","O.O.Cl.COC1=CC2=C(C=C1OC)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N",1.348,6,1,4]
["S2060","Bromhexine HCl","g2","L3800-08","in 10mM DMSO","CFDA,PMDA,HMA","BP2019;EP9.2;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Bromhexine HCl is a medication prescribed for coughs which works by dissolving hard phlegm.",412.59,"611-75-6",{"v":6,"d":"6.00"},14.54,"<1","N/A","http://selleckchem.com/products/bromhexine-hydrochloride.html","C14H20Br2N2.HCl","HCl","N/A","Cl.CN(CC1=CC(=CC(=C1N)Br)Br)C2CCCCC2",4.894,0,1,3]
["S2061","Lovastatin (MK-803)","h2","L3800-08","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Martindale:The Extra Pharmacopoeia","Phase 2","Autophagy,HMG-CoA Reductase","Metabolism","Lovastatin (MK-803, Mevinolin,Mevacor) is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM in a cell-free assay, used for lowering cholesterol (hypolipidemic agent). Lovastatin triggers autophagy.",404.54,"75330-75-5",{"v":8,"d":"8.00"},19.78,"<1","N/A","http://selleckchem.com/products/lovastatin-mevacor.html","C24H36O5","free base","Mevinolin,Mevacor","CCC(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C12",4.218,4,1,7]
["S2062","Tiopronin","a3","L3800-08","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Preregistration","ROS","Immunology & Inflammation","Tiopronin is an antioxidant agent, used for the treatment of cystinuria by controlling the rate of cystine precipitation and excretion.",163.19,"1953-02-2",{"v":32,"d":"32.00"},196.09,{"v":32,"d":"32.00"},196.09,"http://selleckchem.com/products/tiopronin-thiola.html","C5H9NO3S","free base","N/A","CC(S)C(=O)NCC(O)=O",-0.362,2,1,3]
["S2064","Balofloxacin","b3","L3800-08","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","Marketed","Topoisomerase","DNA Damage/DNA Repair","Balofloxacin (Q-35,Q-roxin) is a quinolone antibiotic, inhibiting the synthesis of bacterial DNA by interference with the enqyme DNA gyrase.",389.42,"127294-70-6",{"v":5,"d":"5.00"},12.84,"<1","N/A","http://selleckchem.com/products/balofloxacin.html","C20H24FN3O4","free base","Q-35,Q-roxin","CNC1CCCN(C1)C2=C(OC)C3=C(C=C2F)C(=O)C(=CN3C4CC4)C(O)=O",-0.615,3,1,5]
["S2065","Lafutidine","c3","L3800-08","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","Histamine Receptor","Neuronal Signaling","Lafutidine (FRG-8813), a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.",431.55,"118288-08-7",{"v":86,"d":"86.00"},199.28,"<1","N/A","http://selleckchem.com/products/lafutidine.html","C22H29N3O4S","free base","FRG-8813","O=C(C[S](=O)CC1=CC=CO1)NC\\C=C/COC2=CC(=CC=N2)CN3CCCCC3",1.987,5,1,11]
["S2066","Moxonidine","d3","L3800-08","in 10mM DMSO","DMF,CFDA,HMA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Imidazoline Receptor","GPCR & G Protein","Moxonidine (BDF5895) is a selective agonist at the imidazoline receptor subtype 1, used as antihypertensive agent.",241.68,"75438-57-2",{"v":24,"d":"24.00"},{"v":99.3,"d":"99.30"},"<1","N/A","http://selleckchem.com/products/moxonidine.html","C9H12ClN5O","free base","BDF5895","COC1=NC(=NC(=C1NC2=NCCN2)Cl)C",0.598,4,2,3]
["S2067","Ozagrel HCl","e3","L3800-08","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","P450 (e.g. CYP17),Prostaglandin Receptor","Metabolism","Ozagrel HCl (OKY-046) is a selective <n>thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.",264.71,"78712-43-3",{"v":52,"d":"52.00"},196.44,{"v":52,"d":"52.00"},196.44,"http://selleckchem.com/products/ozagrel-hydrochloride.html","C13H12N2O2.HCl","HCl","OKY-046 HCl","Cl.OC(=O)/C=C/C1=CC=C(C[N]2C=CN=C2)C=C1",1.986,2,0,4]
["S2069","Argatroban (MCI-9038)","f3","L3800-08","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Thrombin","Proteases","Argatroban (MCI-9038) is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant.",508.63,"74863-84-6",{"v":9,"d":"9.00"},17.69,"<1","N/A","http://selleckchem.com/products/argatroban.html","C23H36N6O5S","free base","MCI-9038","CC1CCN(C(C1)C(O)=O)C(=O)C(CCCNC(N)=N)N[S](=O)(=O)C2=CC=CC3=C2NCC(C)C3",1.266,4,4,10]
["S2071","Prulifloxacin (NM441)","g3","L3800-08","in 10mM DMSO","DMF,PMDA,HMA","Martindale:The Extra Pharmacopoeia","Marketed","COVID-19","Microbiology","Prulifloxacin (NM441, AF 3013), the prodrug of ulifloxacin, is a broad-spectrum oral fluoroquinolone antibacterial agent.",461.46,"123447-62-1",{"v":11,"d":"11.00"},23.84,"<1","N/A","http://www.selleckchem.com/products/prulifloxacin-pruvel.html","C21H20FN3O6S","Free Base","AF 3013","CC1SC2=C(C(O)=O)C(=O)C3=CC(=C(C=C3N12)N4CCN(CC4)CC5=C(C)OC(=O)O5)F",0.031,5,0,4]
["S2072","Seratrodast(AA-2414)","h3","L3800-08","in 10mM DMSO","CFDA,PMDA","Martindale the Extra Pharmacopoei","Marketed","Prostaglandin Receptor","Metabolism","Seratrodast (AA-2414, ABT-001) is a potent and selective thromboxane A2 receptor (TP) antagonist which is used primarily in the treatment of asthma and used as anti-inflammatory agent.",354.44,"112665-43-7",{"v":71,"d":"71.00"},200.32,"<1","N/A","http://www.selleck.cn/products/seratrodast.html","C22H26O4","Free Base","ABT-001","CC1=C(C)C(=O)C(=C(C)C1=O)C(CCCCCC(O)=O)C2=CC=CC=C2",5.216,3,0,8]
["S2075","Rosiglitazone (BRL-49653) HCl","a4","L3800-08","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","USP42-NF37;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","PPAR","Metabolism","Rosiglitazone HCl (BRL-49653) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.",393.89,"302543-62-0",{"v":79,"d":"79.00"},200.56,"<1","N/A","http://selleckchem.com/products/rosiglitazone-hydrochloride.html","C18H19N3O3S.HCl","HCl","BRL-49653 HCl","Cl.CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C3=CC=CC=N3",{"v":3.65,"d":"3.650"},4,1,7]
["S2077","Atorvastatin Calcium","b4","L3800-08","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,HMG-CoA Reductase","Metabolism","Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. Atorvastatin Calcium induces apoptosis and autophagy.",1155.34,"134523-03-8",{"v":100,"d":"100.00"},86.55,"<1","N/A","http://selleckchem.com/products/atorvastatin-calcium-lipitor.html","2(C33H34FN2O5).Ca","Calcium","N/A","[Ca++].CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C([N]1CCC(O)CC(O)CC([O-])=O)C3=CC=C(F)C=C3)C4=CC=CC=C4.CC(C)C5=C(C(=O)NC6=CC=CC=C6)C(=C([N]5CCC(O)CC(O)CC([O-])=O)C7=CC=C(F)C=C7)C8=CC=CC=C8",8.163,2,6,24]
["S2078","Famotidine","c4","L3800-08","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Histamine Receptor","Neuronal Signaling","Famotidine (MK208) is a histamine H2–receptor antagonist with IC50 of 0.6 mM, commonly used to treat heartburn, GERD, ulcers, and other digestive conditions.",337.45,"76824-35-6",{"v":67,"d":"67.00"},198.55,"<1","N/A","http://selleckchem.com/products/famotidine-pepcid.html","C8H15N7O2S3","free base","MK208","NC(=N)NC1=NC(=CS1)CSCCC(=N)N[S](N)(=O)=O",-1.328,3,4,9]
["S2079","Moexipril HCl","d4","L3800-08","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","ACE,COVID-19,RAAS","Endocrinology & Hormones","Moexipril HCl (RS-10085) is a potent orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, used for the treatment of hypertension and congestive heart failure.",535.03,"82586-52-5",{"v":20,"d":"20.00"},37.38,"<1","N/A","http://selleckchem.com/products/moexipril-hydrochloride.html","C27H34N2O7.HCl","Hydrochloride","RS-10085","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC(=C(OC)C=C3CC2C(O)=O)OC",1.005,6,1,12]
["S2080","Clevidipine Butyrate","e4","L3800-08","in 10mM DMSO","DMF,HMA","N/A","Marketed","Calcium Channel","Transmembrane Transporters","Clevidipine Butyrate(Cleviprex) is a dihydropyridine calcium channel blocker,  uses as an agent for the reduction of blood pressure.",456.32,"167221-71-8",{"v":91,"d":"91.00"},199.42,"<1","N/A","http://selleckchem.com/products/cleviprex-clevidipine.html","C21H23Cl2NO6","free base","Cleviprex","CCCC(=O)OCOC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2Cl)Cl)C(=O)OC)C",4.145,6,1,10]
["S2082","Adiphenine HCl","f4","L3800-08","in 10mM DMSO","N/A","Martindale the Extra Pharmacopoei","N/A","AChR","Neuronal Signaling","Adiphenine HCl(NSC 129224) is a nicotinic receptor inhibitor, used as an antispasmodic drug.",347.88,"50-42-0",{"v":30,"d":"30.00"},86.24,{"v":70,"d":"70.00"},201.22,"http://selleckchem.com/products/adiphenine-hcl.html","C20H25NO2.HCl","HCl","NSC 129224","Cl.CCN(CC)CCOC(=O)C(C1=CC=CC=C1)C2=CC=CC=C2",4.433,2,0,9]
["S2083","Procaterol HCl","g4","L3800-08","in 10mM DMSO","DMF,CFDA","KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Procaterol HCl (OPC-2009) is a short-acting β2-adrenergic receptor agonist with Kp of 8 nM, used for the treatment of asthma",326.82,"62929-91-3",{"v":65,"d":"65.00"},198.89,{"v":65,"d":"65.00"},198.89,"http://www.selleckchem.com/products/procaterol-hcl.html","C16H22N2O3.HCl","hydrochloride","OPC-2009","Cl.CCC(NC(C)C)C(O)C1=CC=C(O)C2=C1C=CC(=O)N2",2.781,1,4,5]
["S2084","Duloxetine HCl","h4","L3800-08","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Duloxetine HCl (LY-248686) is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).",333.88,"136434-34-9",{"v":67,"d":"67.00"},200.67,"<1","N/A","http://selleckchem.com/products/duloxetine-hcl-cymbalta.html","C18H19NOS.HCl","HCl","LY-248686 HCl","Cl.CNCCC(OC1=C2C=CC=CC2=CC=C1)C3=CC=CS3",4.228,1,1,6]
["S2085","Trimebutine","a5","L3800-08","in 10mM DMSO","DMF,CFDA,PMDA","EP9.3;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","N/A","Opioid Receptor","Neuronal Signaling","Trimebutine (Mebutin) is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain.",387.47,"39133-31-8",{"v":50,"d":"50.00"},129.04,"<1","N/A","http://selleckchem.com/products/trimebutine.html","C22H29NO5","free base","Mebutin","CCC(COC(=O)C1=CC(=C(OC)C(=C1)OC)OC)(N(C)C)C2=CC=CC=C2",4.115,5,0,10]
["S2086","Ivabradine HCl","b5","L3800-08","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Ivabradine HCl (S 16257-2,S-18982 D6 hydrochloride), a new If inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent.",505.05,"148849-67-6",{"v":101,"d":"101.00"},199.98,{"v":82,"d":"82.00"},162.36,"http://selleckchem.com/products/ivabradine-hcl-procoralan.html","C27H36N2O5.HCl","HCl","S 16257-2,S-18982 D6 hydrochloride","Cl.COC1=CC2=C(CC(=O)N(CCCN(C)CC3CC4=CC(=C(OC)C=C34)OC)CC2)C=C1OC",3.753,5,0,10]
["S2087","Rivastigmine Tartrate","c5","L3800-08","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","AChR","Neuronal Signaling","Rivastigmine Tartrate (ENA 713) is a cholinesterase inhibitor with IC50 of 5.5 μM, and used as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease.",400.42,"129101-54-8",{"v":42,"d":"42.00"},104.89,{"v":80,"d":"80.00"},199.79,"http://selleckchem.com/products/rivastigmine-tartrate-exelon.html","C14H22N2O2.C4H6O6","Tartrate","ENA 713","CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C.OC(C(O)C(O)=O)C(O)=O",-2.099,4,2,8]
["S2090","Dexmedetomidine HCl","d5","L3800-08","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Dexmedetomidine HCl((+)-Medetomidine Hydrochloride) is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.",236.74,"145108-58-3",{"v":48,"d":"48.00"},202.75,"<1","N/A","http://selleckchem.com/products/dexmedetomidine-hcl-precedex.html","C13H16N2.HCl","HCl","(+)-Medetomidine Hydrochloride","Cl.CC(C1=CN=C[NH]1)C2=CC=CC(=C2C)C",3.378,1,1,2]
["S2091","Betaxolol","e5","L3800-08","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Phase 3","Adrenergic Receptor","Neuronal Signaling","Betaxolol (SL 75212,Dextrobetaxolol) is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.",307.43,"63659-18-7",{"v":62,"d":"62.00"},201.67,{"v":62,"d":"62.00"},201.67,"http://selleckchem.com/products/betaxolol-betoptic.html","C18H29NO3","free base","SL 75212,Dextrobetaxolol","CC(C)NCC(O)COC1=CC=C(CCOCC2CC2)C=C1",2.577,2,2,11]
["S2092","Detomidine HCl","f5","L3800-08","in 10mM DMSO","DMF","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Adrenergic Receptor","Neuronal Signaling","Detomidine HCl(MPV 253AII) produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.",222.71,"90038-01-0",{"v":45,"d":"45.00"},202.06,{"v":45,"d":"45.00"},202.06,"http://selleckchem.com/products/detomidine-hcl.html","C12H14N2.HCl","HCl","MPV 253AII","Cl.CC1=C(C)C(=CC=C1)CC2=C[NH]C=N2",3.053,1,1,2]
["S2096","Almotriptan Malate","g5","L3800-08","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor","Neuronal Signaling","Almotriptan Malate (LAS 31416) is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults.",469.55,"181183-52-8",{"v":94,"d":"94.00"},200.19,"<1","N/A","http://selleckchem.com/products/almotriptan-malate-axert.html","C17H25N3O2S.C4H6O5","Malate","LAS 31416","CN(C)CCC1=C[NH]C2=CC=C(C[S](=O)(=O)N3CCCC3)C=C12.OC(CC(O)=O)C(O)=O",-1.943,4,2,9]
["S2097","Ambrisentan","h5","L3800-08","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Endothelin Receptor","GPCR & G Protein","Ambrisentan (LU-208075, BSF-208075) is a highly selective antagonist of the endothelin-1 type A receptor, used in the treatment of pulmonary arterial hypertension (PAH).",378.42,"177036-94-1",{"v":76,"d":"76.00"},200.84,"<1","N/A","http://selleckchem.com/products/ambrisentan.html","C22H22N2O4","free base","LU-208075, BSF-208075","COC(C(OC1=NC(=CC(=N1)C)C)C(O)=O)(C2=CC=CC=C2)C3=CC=CC=C3",3.659,5,0,7]
["S2098","Bexarotene (LGD1069)","a6","L3800-08","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Retinoid Receptor","Metabolism","Bexarotene (Targretin, LGD1069) is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.",{"v":348,"d":"348.00"},"153559-49-0",{"v":8,"d":"8.00"},22.99,"<1","N/A","http://selleckchem.com/products/bexarotene.html","C24H28O2","free base","Targretin","CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(O)=O)C(C)(C)CCC2(C)C",6.405,1,0,3]
["S2099","Temocapril HCl","b6","L3800-08","in 10mM DMSO","PMDA,HMA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","ACE,RAAS","Endocrinology & Hormones","Temocapril HCl (CS-622) is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.",513.07,"110221-44-8",{"v":103,"d":"103.00"},200.75,"<1","N/A","http://selleckchem.com/products/temocapril-hcl.html","C23H28N2O5S2.HCl","Hydrochloride","CS-622 HCl","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC2CSC(CN(CC(O)=O)C2=O)C3=CC=CS3",0.787,4,1,11]
["S2101","Gabexate Mesylate","c6","L3800-08","in 10mM DMSO","CFDA","KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","N/A","Serine Protease","Proteases","Gabexate Mesylate(FOY) is a serine protease inhibitor with IC50 of 0.19 μM which is used therapeutically in the treatment of pancreatitis and disseminated intravascular coagulation.",417.48,"56974-61-9",{"v":83,"d":"83.00"},198.81,{"v":12,"d":"12.00"},28.74,"http://selleckchem.com/products/gabexate-mesylate.html","C16H23N3O4.CH4O3S","Mesylate","FOY","CCOC(=O)C1=CC=C(OC(=O)CCCCCNC(N)=N)C=C1.C[S](O)(=O)=O",1.774,4,2,12]
["S2102","Rasagiline Mesylate","d6","L3800-08","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","Marketed","MAO","Metabolism","Rasagiline Mesylate (TVP-1012,(R)-AGN1135 mesylate,TVP1012 mesylate) is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.",267.34,"161735-79-1",{"v":53,"d":"53.00"},198.25,{"v":53,"d":"53.00"},198.25,"http://selleckchem.com/products/rasagiline-mesylate.html","C12H13N.CH4O3S","Mesylate","TVP-1012,(R)-AGN1135 mesylate,TVP1012 mesylate","C[S](O)(=O)=O.C#CCNC1CCC2=CC=CC=C12",2.705,0,1,2]
["S2103","Naltrexone HCl","e6","L3800-08","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Opioid Receptor","Neuronal Signaling","Naltrexone HCl(PTI-901) is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence.",377.86,"16676-29-2",{"v":14,"d":"14.00"},37.05,{"v":14,"d":"14.00"},37.05,"http://selleckchem.com/products/naltrexone-hcl.html","C20H23NO4.HCl","Hydrochloride","PTI-901","Cl.OC1=CC=C2CC3N(CCC45C(OC1=C24)C(=O)CCC35O)CC6CC6",2.039,2,1,2]
["S2104","Levosulpiride","f6","L3800-08","in 10mM DMSO","marketed in Italy","Martindale:The Extra Pharmacopoeia","Marketed","Dopamine Receptor","Neuronal Signaling","Levosulpiride(RV-12309,S-(-)-Sulpiride) is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent.",341.43,"23672-07-3",{"v":69,"d":"69.00"},202.09,"<1","N/A","http://selleckchem.com/products/levosulpiride-levogastrol.html","C15H23N3O4S","free base","RV-12309,S-(-)-Sulpiride","CCN1CCCC1CNC(=O)C2=C(OC)C=CC(=C2)[S](N)(=O)=O",0.704,4,2,6]
["S2105","Pantoprazole","g6","L3800-08","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","USP42-NF37;BP2019;EP9.6;IP2010;CP2005;Martindale:The Extra Pharmacopoeia","N/A","ATPase,Proton Pump","Transmembrane Transporters","Pantoprazole (SKF96022, BY-1023) is a proton pump inhibitor drug that inhibits gastric acid secretion. It works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid.",383.37,"102625-70-7",{"v":76,"d":"76.00"},198.24,"<1","N/A","http://selleckchem.com/products/pantoprazole-protonix.html","C16H15F2N3O4S","free base","SKFSKF96022, BY-1023","COC1=C(OC)C(=NC=C1)C[S](=O)C2=NC3=CC=C(OC(F)F)C=C3[NH]2",2.737,6,1,7]
["S2108","Flunixin Meglumin","h6","L3800-08","in 10mM DMSO","N/A","USP42-NF37;BP2019;EP9.2","N/A","COX","Neuronal Signaling","Flunixin Meglumin(Banamine) is a potent inhibitor of the enzyme cyclooxygenase (COX) used as analgesic agent with anti-inflammatory and antipyretic activity.",491.46,"42461-84-7",{"v":98,"d":"98.00"},199.41,{"v":98,"d":"98.00"},199.41,"http://selleckchem.com/products/flunixin-meglumin.html","C14H11F3N2O2.C7H17NO5","Meglumin","Banamine","CNCC(O)C(O)C(O)C(O)CO.CC1=C(C=CC=C1NC2=NC=CC=C2C(O)=O)C(F)(F)F",-1.676,2,7,10]
["S2109","Imidapril HCl","a7","L3800-08","in 10mM DMSO","DMF,CFD,PMDA,HMA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","ACE,RAAS","Endocrinology & Hormones","Imidapril HCl(TA-6366) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.",441.91,"89396-94-1",{"v":88,"d":"88.00"},199.14,{"v":54,"d":"54.00"},{"v":122.2,"d":"122.20"},"http://selleckchem.com/products/imidapril-tanatril.html","C20H27N3O6.HCl","Hydrochloride","TA-6366","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C(CN(C)C2=O)C(O)=O",-1.197,5,1,10]
["S2111","Lapatinib (GW-572016)","b7","L3800-08","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,EGFR,Ferroptosis,HER2","Protein Tyrosine Kinase","Lapatinib (GW-572016, GSK572016, GW2016), used in the form of Lapatinib Ditosylate, is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively. Lapatinib induces ferroptosis and autophagic cell death.",581.06,"231277-92-2",{"v":100,"d":"100.00"},{"v":172.1,"d":"172.10"},"<1","N/A","http://selleckchem.com/products/lapatinib.html","C29H26ClFN4O4S","free base","GSK572016, GW2016","C[S](=O)(=O)CCNCC1=CC=C(O1)C2=CC=C3N=CN=C(NC4=CC=C(OCC5=CC=CC(=C5)F)C(=C4)Cl)C3=C2",6.041,6,2,11]
["S2113","Cisatracurium Besylate","c7","L3800-08","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;EP9.4;BP2019;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Cisatracurium Besylate(51W89) is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.",1243.48,"96946-42-8",{"v":249,"d":"249.00"},200.24,{"v":47,"d":"47.00"},{"v":37.8,"d":"37.80"},"http://selleckchem.com/products/cisatracurium-besylate-nimbex.html","C53H72N2O12.2C6H5O3S","Besylate","51W89","COC1=CC=C(CC2C3=CC(=C(OC)C=C3CC[N+]2(C)CCC(=O)OCCCCCOC(=O)CC[N+]4(C)CCC5=CC(=C(OC)C=C5C4CC6=CC=C(OC)C(=C6)OC)OC)OC)C=C1OC.[O-][S](=O)(=O)C7=CC=CC=C7.[O-][S](=O)(=O)C8=CC=CC=C8",3.646,12,0,28]
["S2114","Dronedarone HCl","d7","L3800-08","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","Calcium Channel,Potassium Channel,Sodium Channel","Transmembrane Transporters","Dronedarone HCl (SR33589) is a multichannel blocker targeting potassium channel, sodium channel and calcium channel, used as an antiarrhythmic drug for treatment of atrial fibrillation (AF).",593.22,"141625-93-6",{"v":80,"d":"80.00"},134.86,"<1","N/A","http://selleckchem.com/products/dronedarone-hcl-multaq.html","C31H44N2O5S.HCl","HCl","SR33589","Cl.CCCCN(CCCC)CCCOC1=CC=C(C=C1)C(=O)C2=C(CCCC)OC3=CC=C(N[S](C)(=O)=O)C=C23",7.397,5,1,18]
["S2116","Conivaptan HCl","e7","L3800-08","in 10mM DMSO","FDA,NDC","Martindale:The Extra Pharmacopoeia","Marketed","Vasopressin Receptor","GPCR & G Protein","Conivaptan HCl(YM 087) is an orally active, non-peptide, vasopressin V1A and V2 receptor antagonist, used in the treatment of euvolemic and hypervolemic hyponatremia.",535.04,"168626-94-6",{"v":107,"d":"107.00"},199.99,"<1","N/A","http://selleckchem.com/products/conivaptan-hcl-vaprisol.html","C32H26N4O2.HCl","HCl","YM 087","Cl.CC1=NC2=C([NH]1)C3=C(C=CC=C3)N(CC2)C(=O)C4=CC=C(NC(=O)C5=C(C=CC=C5)C6=CC=CC=C6)C=C4",{"v":5.68,"d":"5.680"},3,2,4]
["S2118","Ibutilide Fumarate","f7","L3800-08","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;Martindale:The Extra Pharmacopoeia","Marketed","Sodium Channel","Transmembrane Transporters","Ibutilide Fumarate (U-70226E,Corvert Fumarate) is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells.",885.23,"122647-32-9",{"v":89,"d":"89.00"},100.54,{"v":89,"d":"89.00"},100.54,"http://selleckchem.com/products/ibutilide-fumarate.html","(C20H36N2O3S)2.C4H4O4","Fumarate","U-70226E,Corvert Fumarate","CCCCCCCN(CC)CCCC(O)C1=CC=C(N[S](C)(=O)=O)C=C1.CCCCCCCN(CC)CCCC(O)C2=CC=C(N[S](C)(=O)=O)C=C2.OC(=O)\\C=C\\C(O)=O",1.954,6,4,30]
["S2119","Probucol","g7","L3800-08","in 10mM DMSO","FDA,DMF,CFDA","USP42-NF37;JP17;Martindale:The Extra Pharmacopoeia;CP2005","N/A","LDL","Metabolism","Probucol (DH-581) is an anti-hyperlipidemic drug by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.",516.84,"23288-49-5",{"v":103,"d":"103.00"},199.29,"<1","N/A","http://selleckchem.com/products/probucol.html","C31H48O2S2","free base","DH-581","CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SC(C)(C)SC2=CC(=C(O)C(=C2)C(C)(C)C)C(C)(C)C",9.779,0,2,8]
["S2120","Arbidol HCl","h7","L3800-08","in 10mM DMSO","CFDA","N/A","N/A","Influenza Virus","Microbiology","Arbidol HCl (Umifenovir) is a broad-spectrum antiviral compound that blocks viral fusion, used in treatment of influenza and other respiratory viral infections.",513.88,"131707-23-8",{"v":103,"d":"103.00"},200.44,"<1","N/A","http://selleckchem.com/products/Arbidol-hcl.html","C22H25BrN2O3S.HCl","Hydrochloride","Umifenovir hydrochloride, Arbidol hydrochloride","Cl.CCOC(=O)C1=C(CSC2=CC=CC=C2)[N](C)C3=CC(=C(O)C(=C13)CN(C)C)Br",5.698,2,1,8]
["S2123","Dextrose","a8","L3800-08","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP38-NF33;IP2010","Phase 4","Others","Others","Dextrose (D-glucose), a simple sugar (monosaccharide), is an important carbohydrate in biology.",180.16,"50-99-7",{"v":36,"d":"36.00"},199.82,{"v":36,"d":"36.00"},199.82,"http://selleckchem.com/products/Dextrose(D-glucose).html","C6H12O6","free base","D-glucose","OCC(O)C(O)C(O)C(O)C=O",-2.791,1,5,5]
["S2124","Xylose","b8","L3800-08","in 10mM DMSO","FDA,DMF,HMA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Xylose(Wood sugar) is a sugar first isolated from wood.",150.13,"25990-60-7, 58-86-6",{"v":30,"d":"30.00"},199.83,{"v":30,"d":"30.00"},199.83,"http://selleckchem.com/products/Xylose.html","C5H10O5","free base","Wood sugar","OCC(O)C(O)C(O)C=O",{"v":-2.28,"d":"-2.280"},1,4,4]
["S2125","Mestranol","c8","L3800-08","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Estrogen/progestogen Receptor","Endocrinology & Hormones","Mestranol is the 3-methyl ether of ethinyl estradiol, which is a potent estrogen receptor agonist and used as oral contraceptives.",310.43,"72-33-3",{"v":15,"d":"15.00"},48.32,"<1","N/A","http://selleckchem.com/products/Mestranol.html","C21H26O2","free base","N/A","COC1=CC2=C(C=C1)C3CCC4(C)C(CCC4(O)C#C)C3CC2",5.112,1,0,1]
["S2126","Naftopidil","d8","L3800-08","in 10mM DMSO","DMF,CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Naftopidil (KT-611) is a selective α1-adrenergic receptor antagonist with Ki of 3.7 nM, 20 nM, and 1.2 nM for α1a, α1b, and α1d, respectively, used for the treatment of benign prostatic hyperplasia.",392.49,"57149-07-2",{"v":79,"d":"79.00"},201.28,"<1","N/A","http://selleckchem.com/products/Naftopidil(Flivas).html","C24H28N2O3","Free Base","KT-611","COC1=CC=CC=C1N2CCN(CC2)CC(O)COC3=C4C=CC=CC4=CC=C3",3.962,2,1,7]
["S2127","S-(+)-Rolipram","e8","L3800-08","in 10mM DMSO","DMF","N/A","N/A","PDE","Metabolism","S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.",275.34,"85416-73-5",{"v":55,"d":"55.00"},199.75,"<1","N/A","http://selleckchem.com/products/sRolipram.html","C16H21NO3","free base","N/A","COC1=C(OC2CCCC2)C=C(C=C1)C3CNC(=O)C3",2.349,3,1,4]
["S2128","Bazedoxifene (WAY-140424) HCl","f8","L3800-08","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Bazedoxifene HCl (WAY-140424, TSE-424) is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of  23 nM and 89 nM, respectively.",507.06,"198480-56-7",{"v":101,"d":"101.00"},199.19,"<1","N/A","http://selleckchem.com/products/bazedoxifene-hcl.html","C30H34N2O3.HCl","Hydrochloride","TSE-424","Cl.CC1=C([N](CC2=CC=C(OCCN3CCCCCC3)C=C2)C4=CC=C(O)C=C14)C5=CC=C(O)C=C5",7.602,1,2,7]
["S2130","Atropine sulfate monohydrate","g8","L3800-08","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.3;BP2019;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia;CP2005","Registered","AChR,ADC Cytotoxin","Neuronal Signaling","Atropine sulfate monohydrate is a competitive antagonist for the muscarinic acetylcholine receptor, used to decrease the production of saliva and secretions of the airway prior to surgery.",694.83,"5908-99-6",{"v":139,"d":"139.00"},200.05,{"v":139,"d":"139.00"},200.05,"http://selleckchem.com/products/Atropine-sulfate-monohydrate.html","2(C17H23NO3).H2O.H2SO4","Sulfate monohydrate","N/A","O.CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN4C5CCC4CC(C5)OC(=O)C(CO)C6=CC=CC=C6.O[S](O)(=O)=O",2.628,4,2,10]
["S2131","Roflumilast (B9302-107)","h8","L3800-08","in 10mM DMSO","FDA,DMF,EMA,NDC","Martindale:The Extra Pharmacopoeia","Marketed","PDE","Metabolism","Roflumilast (APTA 2217, B9302-107, BY 217, BYK 20869) is a selective inhibitor of PDE4 with IC50 of 0.2-4.3 nM in a cell-free assay.",403.21,"162401-32-3",{"v":81,"d":"81.00"},200.89,"<1","N/A","http://selleckchem.com/products/Roflumilast(Daxas).html","C17H14Cl2F2N2O3","free base","APTA 2217, B9302-107, BY 217, BYK 20869","FC(F)OC1=CC=C(C=C1OCC2CC2)C(=O)NC3=C(Cl)C=NC=C3Cl",4.402,4,1,7]
["S2134","AZD8330","a9","L3800-08","in 10mM DMSO","N/A","N/A","Phase 1","MEK","MAPK","AZD8330 (ARRY704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.",461.23,"869357-68-6",{"v":92,"d":"92.00"},199.47,"<1","N/A","http://selleckchem.com/products/AZD8330(ARRY-424704).html","C16H17FIN3O4","free base","ARRY704","CN1C(=O)C(=CC(=C1NC2=C(F)C=C(I)C=C2)C(=O)NOCCO)C",1.653,3,3,6]
["S2149","GSK1292263","b9","L3800-08","in 10mM DMSO","N/A","N/A","Phase 2","GPR","Endocrinology & Hormones","GSK1292263 is a novel GPR119 agonist, showing potential for the treatment of type 2 diabetes. Phase 2.",456.56,"1032823-75-8",{"v":34,"d":"34.00"},74.47,"<1","N/A","http://selleckchem.com/products/GSK1292263.html","C23H28N4O4S","free base","N/A","CC(C)C1=NOC(=N1)N2CCC(CC2)COC3=CN=C(C=C3)C4=CC=C(C=C4)[S](C)(=O)=O",3.893,7,0,7]
["S2151","Sonidegib (NVP-LDE225)","c9","L3800-08","in 10mM DMSO","FDA,DMF,EMA,NDC","N/A","Marketed","Hedgehog/Smoothened","Stem Cells & Wnt","Sonidegib (Erismodegib, NVP-LDE225) is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human) in cell-free assays, respectively. Phase 3.",{"v":485.5,"d":"485.50"},"956697-53-3",{"v":97,"d":"97.00"},199.79,"<1","N/A","http://selleckchem.com/products/LDE225(NVP-LDE225).html","C26H26F3N3O3","free base","Erismodegib","CC1CN(CC(C)O1)C2=CC=C(NC(=O)C3=C(C)C(=CC=C3)C4=CC=C(OC(F)(F)F)C=C4)C=N2",6.732,4,1,6]
["S2154","Dabigatran (BIBR-1048) etexilate","d9","L3800-08","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Thrombin","Proteases","Dabigatran Etexilate (BIBR-1048) is the prodrug of dabigatran, a potent, nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule.",627.73,"211915-06-9",{"v":126,"d":"126.00"},200.72,"<1","N/A","http://selleckchem.com/products/BIBR-1048(Dabigatran-etexilate).html","C34H41N7O5","free base","BIBR-1048","CCCCCCOC(=O)N=C(N)C1=CC=C(NCC2=NC3=C(C=CC(=C3)C(=O)N(CCC(=O)OCC)C4=CC=CC=N4)[N]2C)C=C1",5.751,8,2,17]
["S2155","LY2608204","e9","L3800-08","in 10mM DMSO","N/A","N/A","Phase 2","Carbohydrate Metabolism","Metabolism","LY2608204 activates glucokinase (GK) with EC50 of 42 nM. Phase 2.",559.81,"1234703-40-2",{"v":112,"d":"112.00"},200.07,"<1","N/A","http://selleckchem.com/products/ly2608204.html","C28H37N3O3S3","free base","N/A","O=C(NC1=NC=C(SCCN2CCCC2)S1)C3(CC3C4CCCCC4)C5=CC=C(C=C5)[S](=O)(=O)C6CC6",5.393,4,1,10]
["S2156","LY2886721","f9","L3800-08","in 10mM DMSO","N/A","N/A","Phase 2","BACE","Neuronal Signaling","LY2886721 is a BACE inhibitor used for the treatment of Alzheimer's Disease. Phase 1/2.",390.41,"1262036-50-9",{"v":9,"d":"9.00"},23.05,"<1","N/A","http://selleckchem.com/products/LY-2886721.html","C18H16F2N4O2S","free base","N/A","NC1=NC2(COCC2CS1)C3=CC(=CC=C3F)NC(=O)C4=NC=C(F)C=C4",2.134,4,2,3]
["S2158","KW-2449","g9","L3800-08","in 10mM DMSO","N/A","N/A","Phase 1","Aurora Kinase,Bcr-Abl,FLT3","Angiogenesis","KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 with IC50 of 6.6 nM, modestly potent to FGFR1, Bcr-Abl and Aurora A; little effect on PDGFRβ, IGF-1R, EGFR. Phase 1.",{"v":332.4,"d":"332.40"},"1000669-72-6",{"v":67,"d":"67.00"},201.56,"<1","N/A","http://selleckchem.com/products/KW-2449.html","C20H20N4O","free base","N/A","O=C(N1CCNCC1)C2=CC=C(C=C2)/C=C/C3=N[NH]C4=C3C=CC=C4",2.723,2,2,3]
["S2159","Tebipenem Pivoxil","h9","L3800-08","in 10mM DMSO","marketed in Japan","N/A","Marketed","Antibiotics","Microbiology","Tebipenem pivoxil (L-084, ME1211,TBPM-PI,LJC 11036) is an oral carbapenem antibiotic, use to treat otolaryngologic and respiratory infections.",497.63,"161715-24-8",{"v":99,"d":"99.00"},198.94,"<1","N/A","http://selleckchem.com/products/Tebipenem-pivoxil(L-084).html","C22H31N3O6S2","free base","L-084, ME1211,TBPM-PI,LJC 11036","CC(O)C1C2C(C)C(=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C)SC3CN(C3)C4=NCCS4",1.782,6,1,10]
["S2160","Almorexant HCl","a10","L3800-08","in 10mM DMSO","N/A","N/A","Phase 3","OX Receptor","GPCR & G Protein","Almorexant HCl (ACT-078573) is an orally active, dual orexin receptor antagonist with IC50 of 6.6 nM and 3.4 nM for OX1 and OX2 receptor, respectively. Phase 3.",549.02,"913358-93-7",{"v":72,"d":"72.00"},131.14,"<1","N/A","http://selleckchem.com/products/almorexant-hcl.html","C29H32ClF3N2O3","Hydrochloride","ACT-078573 HCl","Cl.CNC(=O)C(N1CCC2=C(C=C(OC)C(=C2)OC)C1CCC3=CC=C(C=C3)C(F)(F)F)C4=CC=CC=C4",6.438,3,1,9]
["S2161","RAF265 (CHIR-265)","b10","L3800-08","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,Raf,VEGFR","MAPK","RAF265 (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM in cell-free assays. RAF265 (CHIR-265) induces cell cycle arrest and apoptosis. Phase 2.",518.41,"927880-90-8",{"v":100,"d":"100.00"},{"v":192.9,"d":"192.90"},"<1","N/A","http://selleckchem.com/products/RAF265(CHIR-265).html","C24H16F6N6O","free base","N/A","C[N]1C(=NC2=C1C=CC(=C2)OC3=CC=NC(=C3)C4=NC=C([NH]4)C(F)(F)F)NC5=CC=C(C=C5)C(F)(F)F",6.469,4,2,7]
["S2162","AZD1480","c10","L3800-08","in 10mM DMSO","N/A","N/A","Phase 2","JAK","JAK/STAT","AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM in a cell-free assay, selectivity against JAK3 and Tyk2, and to a smaller extent against JAK1. Phase 1.",348.77,"935666-88-9",{"v":70,"d":"70.00"},200.71,"<1","N/A","http://www.selleck.cn/products/AZD1480.html","C14H14ClFN8","free base","N/A","CC(NC1=NC=C(Cl)C(=N1)NC2=N[NH]C(=C2)C)C3=NC=C(F)C=N3",2.645,5,3,5]
["S2167","Bazedoxifene (TSE-424) acetate","d10","L3800-08","in 10mM DMSO","FDA,DMF,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Bazedoxifene Acetate (WAY-140424,TSE-424 acetate) is a third generation selective estrogen receptor modulator (SERM).",530.65,"198481-33-3",{"v":100,"d":"100.00"},188.45,"<1","N/A","http://selleckchem.com/products/Bazedoxifene-acetate.html","C30H34N2O3.C2H4O2","Acetate","WAY-140424,TSE-424 acetate","CC(O)=O.CC1=C([N](CC2=CC=C(OCCN3CCCCCC3)C=C2)C4=CC=C(O)C=C14)C5=CC=C(O)C=C5",3.981,2,2,7]
["S2169","Rosuvastatin (ZD4522) calcium","e10","L3800-08","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","COVID-19,HMG-CoA Reductase","Metabolism","Rosuvastatin Calcium (ZD4522 calcium) is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM in a cell-free assay.",500.57,"147098-20-2",{"v":100,"d":"100.00"},199.77,"<1","N/A","http://selleckchem.com/products/Rosuvastatin-calcium(Crestor).html","C22H28FN3O6S.1/2Ca","Calcium salt","ZD4522 calcium","[Ca++].CC(C)C1=C(\\C=C\\C(O)CC(O)CC([O-])=O)C(=NC(=N1)N(C)[S](C)(=O)=O)C2=CC=C(F)C=C2.CC(C)C3=C(\\C=C\\C(O)CC(O)CC([O-])=O)C(=NC(=N3)N(C)[S](C)(=O)=O)C4=CC=C(F)C=C4",1.906,8,4,20]
["S2170","Givinostat (ITF2357)","f10","L3800-08","in 10mM DMSO","N/A","N/A","Phase 3","HDAC","Cytoskeletal Signaling","Givinostat (ITF2357) is a potent HDAC inhibitor for maize HD2, HD1B and HD1A with IC50 of 10 nM, 7.5 nM and 16 nM in cell-free assays. Phase 2.",475.97,"732302-99-7",{"v":95,"d":"95.00"},199.59,"<1","N/A","http://selleckchem.com/products/ITF2357(Givinostat).html","C24H27N3O4.HCl.H2O","Chloride","N/A","O.Cl.CCN(CC)CC1=CC2=C(C=C1)C=C(COC(=O)NC3=CC=C(C=C3)C(=O)NO)C=C2",4.046,3,2,9]
["S2173","Telotristat Etiprate (LX 1606 Hippurate)","g10","L3800-08","in 10mM DMSO","FDA","N/A","Marketed","Hydroxylase","Metabolism","Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. Phase 3.",754.15,"1137608-69-5",{"v":100,"d":"100.00"},{"v":132.6,"d":"132.60"},"<1","N/A","http://selleckchem.com/products/telotristat-etiprate-lx-1606-hippurate.html","C27H26ClF3N6O3.C9H9NO3","Hippuric acid","N/A","CCOC(=O)C(N)CC1=CC=C(C=C1)C2=CC(=NC(=N2)N)OC(C3=CC=C(Cl)C=C3[N]4C=CC(=N4)C)C(F)(F)F.OC(=O)CNC(=O)C5=CC=CC=C5",3.747,8,3,14]
["S2177","Dichlorphenamide","h10","L3800-08","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","Marketed","Carbonic Anhydrase","Metabolism","Dichlorphenamide (Diclofenamide) is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class.",305.16,"120-97-8",{"v":61,"d":"61.00"},199.89,"N/A","N/A","http://www.selleckchem.com/products/Dichlorphenamide(Diclofenamide).html","C6H6Cl2N2O4S2","Free Base","Diclofenamide","N[S](=O)(=O)C1=CC(=C(Cl)C(=C1)[S](N)(=O)=O)Cl","N/A","N/A","N/A","N/A"]
["S2178","AG-14361","a11","L3800-08","in 10mM DMSO","N/A","N/A","Phase 3","PARP","DNA Damage/DNA Repair","AG14361 is a potent inhibitor of PARP1 with Ki of <5 nM in a cell-free assay. It is at least 1000-fold more potent than the benzamides.",320.39,"328543-09-5",{"v":12,"d":"12.00"},37.45,"<1","N/A","http://selleckchem.com/products/AG14361.html","C19H20N4O","free base","N/A","CN(C)CC1=CC=C(C=C1)C2=NC3=CC=CC4=C3[N]2CCNC4=O",2.576,2,1,3]
["S2179","Gandotinib (LY2784544)","b11","L3800-08","in 10mM DMSO","N/A","N/A","Phase 2","JAK","JAK/STAT","Gandotinib (LY2784544) is a potent JAK2 inhibitor with IC50 of 3 nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.",469.94,"1229236-86-5",{"v":94,"d":"94.00"},200.03,"<1","N/A","http://selleckchem.com/products/LY2784544.html","C23H25ClFN7O","free base","N/A","CC1=N[NH]C(=C1)NC2=N[N]3C(=C(C)N=C3C(=C2)CN4CCOCC4)CC5=CC=C(Cl)C=C5F",3.938,4,2,6]
["S2180","Ixazomib (MLN2238)","c11","L3800-08","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Autophagy,Proteasome","Proteases","Ixazomib (MLN2238) inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM in cell-free assays, respectively, also inhibits the caspase-like (β1) and trypsin-like (β2) proteolytic sites, with IC50 of 31 and 3500 nM. Ixazomib (MLN2238) induces autophagy. Phase 3.",361.03,"1072833-77-2",{"v":72,"d":"72.00"},199.43,"<1","N/A","http://selleckchem.com/products/MLN-2238.html","C14H19BCl2N2O4","Free Base","N/A","CC(C)CC(NC(=O)CNC(=O)C1=C(Cl)C=CC(=C1)Cl)B(O)O",3.344,2,2,7]
["S2181","Ixazomib Citrate (MLN9708) Analogue","d11","L3800-08","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Autophagy,Proteasome","Proteases","Ixazomib Citrate (MLN9708) Analogue is the analogue of Ixazomib Citrate (MLN9708) from WO2016165677A1. Ixazomib Citrate (MLN9708) immediately hydrolyzed to Ixazomib (MLN2238), the biologically active form, on exposure to aqueous solutions or plasma. Ixazomib (MLN2238) inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50/Ki of 3.4 nM/0.93 nM in cell-free assays, less potent to β1 and little activity to β2. Ixazomib (MLN2238) induces autophagy. Phase 3.",517.12,"1201902-80-8",{"v":100,"d":"100.00"},193.38,"<1","N/A","http://selleckchem.com/products/MLN9708.html","C20H23BCl2N2O9","free base","N/A","CC(C)CC(NC(=O)CNC(=O)C1=C(Cl)C=CC(=C1)Cl)B2OC(=O)CC(CC(O)=O)(O2)C(O)=O",3.497,7,2,10]
["S2182","SB743921 HCl","e11","L3800-08","in 10mM DMSO","N/A","N/A","Phase 2","Kinesin","Cytoskeletal Signaling","SB743921 is a kinesin spindle protein (KSP) inhibitor with Ki of 0.1 nM, almost no affinity to MKLP1, Kin2, Kif1A, Kif15, KHC, Kif4 and CENP-E. Phase 1/2.",553.52,"940929-33-9",{"v":111,"d":"111.00"},200.53,{"v":22,"d":"22.00"},39.75,"http://selleckchem.com/products/SB-743921.html","C31H33N2O3.HCl","Hydrochloride","N/A","Cl.CC(C)C(N(CCCN)C(=O)C1=CC=C(C)C=C1)C2=C(CC3=CC=CC=C3)C(=O)C4=C(O2)C=C(Cl)C=C4",6.536,3,1,9]
["S2183","Infigratinib (BGJ398)","f11","L3800-08","in 10mM DMSO","N/A","N/A","Phase 3","FGFR","Angiogenesis","Infigratinib (BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM in cell-free assays, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes. Phase 2.",560.48,"872511-34-7",{"v":27,"d":"27.00"},48.17,"<1","N/A","http://www.selleck.cn/products/bgj398-nvp-bgj398.html","C26H31Cl2N7O3","Free Base","NVP-BGJ398","CCN1CCN(CC1)C2=CC=C(NC3=NC=NC(=C3)N(C)C(=O)NC4=C(Cl)C(=CC(=C4Cl)OC)OC)C=C2",5.342,5,2,8]
["S2185","Allitinib tosylate","g11","L3800-08","in 10mM DMSO","N/A","N/A","Phase 2","EGFR","Protein Tyrosine Kinase","Allitinib tosylate (AST-1306 TsOH, AST-6) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, also effective in mutation EGFR T790M/L858R, more potent to ErbB2-overexpressing cells, 3000-fold selective for ErbB family than other kinases.",621.08,"1050500-29-2",{"v":124,"d":"124.00"},199.65,"<1","N/A","https://www.selleckchem.com/products/allitinib-tosylate.html","C24H18ClFN4O2,C7H8O3S","Mesylate","AST-1306 TsOH, AST-6","CC1=CC=C(C=C1)[S](O)(=O)=O.FC2=CC(=CC=C2)COC3=CC=C(NC4=C5C=C(NC(=O)C=C)C=CC5=NC=N4)C=C3Cl",7.381,4,2,8]
["S2187","Avasimibe (CI-1011)","h11","L3800-08","in 10mM DMSO","N/A","N/A","Phase 3","Acyltransferase,P450 (e.g. CYP17)","Metabolism","Avasimibe (CI-1011, PD-148515) inhibits ACAT with IC50 of 3.3 μM, also inhibits human P450 isoenzymes CYP2C9, CYP1A2 and CYP2C19 with IC50 of 2.9 μM, 13.9 μM and 26.5 μM, respectively.",501.72,"166518-60-1",{"v":100,"d":"100.00"},199.31,"<1","N/A","http://selleckchem.com/products/Avasimibe(CI-1011).html","C29H43NO4S","free base","PD-148515","CC(C)C1=CC(=C(CC(=O)N[S](=O)(=O)OC2=C(C=CC=C2C(C)C)C(C)C)C(=C1)C(C)C)C(C)C",8.227,2,1,10]
["S2188","Phenprocoumon","a2","L3800-09","in 10mM DMSO","FDA,HMA","Martindale the Extra Pharmacopoei","N/A","5-alpha Reductase","Angiogenesis","Phenprocoumon (Marcoumar, Marcumar and Falithrom,Ro 1-4849) is a vitamin K reductase with an IC50 of 1 μM",280.32,"435-97-2,53621-47-9 (sodium salt)",{"v":56,"d":"56.00"},199.77,"<1","N/A","http://www.selleck.cn/products/Phenprocoumon(Marcumar).html","C18H16O3","free base","Marcoumar, Marcumar and Falithrom,Ro 1-4849","CCC(C1=CC=CC=C1)C2=C(O)C3=CC=CC=C3OC2=O",4.004,2,1,3]
["S2192","Sapitinib (AZD8931)","b2","L3800-09","in 10mM DMSO","N/A","N/A","Phase 1/2","EGFR,HER2","Protein Tyrosine Kinase","Sapitinib (AZD8931) is a reversible, ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 with IC50 of 4 nM, 3 nM and 4 nM in cell-free assays, more potent than Gefitinib or Lapatinib against NSCLC cell, 100-fold more selective for the ErbB family than MNK1 and Flt. Phase 2.",473.93,"848942-61-0",{"v":40,"d":"40.00"},{"v":84.4,"d":"84.40"},"<1","N/A","http://selleckchem.com/products/AZD8931.html","C23H25ClFN5O3","free base","N/A","CNC(=O)CN1CCC(CC1)OC2=C(OC)C=C3N=CN=C(NC4=C(F)C(=CC=C4)Cl)C3=C2",3.485,5,2,7]
["S2193","GSK461364","c2","L3800-09","in 10mM DMSO","N/A","N/A","Phase 1","PLK","Cell Cycle","GSK461364 (GSK461364A) inhibits purified Plk1 with Ki of 2.2 nM in a cell-free assay. It is more than 1000-fold selective against Plk2/3.",{"v":543.6,"d":"543.60"},"929095-18-1",{"v":10,"d":"10.00"},{"v":18.4,"d":"18.40"},"<1","N/A","http://selleckchem.com/products/GSK461364.html","C27H28F3N5O2S","free base","GSK461364A","CC(OC1=C(SC(=C1)[N]2C=NC3=C2C=C(CN4CCN(C)CC4)C=C3)C(N)=O)C5=CC=CC=C5C(F)(F)F",5.125,3,1,8]
["S2194","R406","d2","L3800-09","in 10mM DMSO","N/A","N/A","Marketed","Apoptosis related,FLT3,Syk","Angiogenesis","R406 is a potent Syk inhibitor with IC50 of 41 nM in cell-free assays, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. R406 induces apoptosis. Phase 1.",628.63,"841290-81-1",{"v":100,"d":"100.00"},159.08,"<1","N/A","http://selleckchem.com/products/R406.html","C22H23FN6O5.C6H6O3S","Besylate","N/A","COC1=C(OC)C(=CC(=C1)NC2=NC(=C(F)C=N2)NC3=NC4=C(OC(C)(C)C(=O)N4)C=C3)OC.O[S](=O)(=O)C5=CC=CC=C5",5.044,8,3,8]
["S2195","Lexibulin (CYT997)","e2","L3800-09","in 10mM DMSO","N/A","N/A","Phase 2","Microtubule Associated","Cytoskeletal Signaling","Lexibulin (CYT997, SRI-32007) is a potent microtubule polymerization inhibitor with IC50 of 10-100 nM in cancer cell lines. Phase 2.",434.53,"917111-44-5",{"v":86,"d":"86.00"},197.91,"<1","N/A","http://selleckchem.com/products/CYT997.html","C24H30N6O2","free base","SRI-32007","CCCC(NC1=C(C)C=NC(=N1)C2=CC(=C(NC(=O)NCC)C=C2)OC)C3=CC=CN=C3",3.744,5,3,9]
["S2198","SGI-1776 free base","f2","L3800-09","in 10mM DMSO","N/A","N/A","Phase 1","Apoptosis related,Autophagy,FLT3,Haspin Kinase,Pim","JAK/STAT","SGI-1776 free base is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM in a cell-free assay, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin. SGI-1776 induces apoptosis and autophagy.",405.42,"1025065-69-3",{"v":81,"d":"81.00"},199.79,"<1","N/A","http://selleckchem.com/products/SGI-1776.html","C20H22F3N5O","free base","N/A","CN1CCC(CC1)CNC2=N[N]3C(=NC=C3C4=CC=CC(=C4)OC(F)(F)F)C=C2",5.206,3,1,6]
["S2199","Aliskiren Hemifumarate","g2","L3800-09","in 10mM DMSO","FDA,DMF,NDC","N/A","Marketed","RAAS","Endocrinology & Hormones","Aliskiren hemifumarate(CGP 60536 hemifumarate, CGP60536B hemifumarate, SPP 100 hemifumarate) is a direct renin inhibitor with IC50 of 1.5 nM.",609.83,"173334-58-2",{"v":100,"d":"100.00"},163.98,{"v":100,"d":"100.00"},163.98,"http://selleckchem.com/products/Aliskiren-hemifumarate.html","C30H53N3O6.1/2C4H4O4","fumarate salt","CGP 60536 hemifumarate, CGP60536B hemifumarate, SPP 100 hemifumarate","COCCCOC1=C(OC)C=CC(=C1)CC(CC(N)C(O)CC(C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C.COCCCOC2=C(OC)C=CC(=C2)CC(CC(N)C(O)CC(C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C.OC(=O)\\C=C\\C(O)=O",1.735,12,8,40]
["S2216","Mubritinib (TAK 165)","a3","L3800-09","in 10mM DMSO","N/A","N/A","Phase 1","HER2","Protein Tyrosine Kinase","Mubritinib (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM in BT-474 cell; no activity to EGFR, FGFR, PDGFR, JAK1, Src and Blk in BT-474 cell line.",468.47,"366017-09-6",{"v":13,"d":"13.00"},27.75,"<1","N/A","http://selleckchem.com/products/Mubritinib-TAK-165.html","C25H23F3N4O2","free base","N/A","FC(F)(F)C1=CC=C(\\C=C\\C2=NC(=CO2)COC3=CC=C(CCCC[N]4C=CN=N4)C=C3)C=C1",5.844,5,0,11]
["S2217","Irinotecan (CPT-11) HCl Trihydrate","b3","L3800-09","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;EP9.3;BP2018;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Topoisomerase","DNA Damage/DNA Repair","Irinotecan (CPT-11) prevents DNA from unwinding by inhibition of topoisomerase 1.",677.18,"136572-09-3",{"v":100,"d":"100.00"},147.67,{"v":1,"d":"1.00"},1.48,"http://selleckchem.com/products/Irinotecan-Hcl-Trihydrate-Campto.html","C33H38N4O6.HCl.3H2O","HCl & trihydrat","CPT-11 HCl Trihydrate","O.O.O.Cl.CCC1=C2CN3C(=O)C4=C(C=C3C2=NC5=CC=C(OC(=O)N6CCC(CC6)N7CCCCC7)C=C15)C(O)(CC)C(=O)OC4",3.446,6,0,5]
["S2219","Momelotinib (CYT387)","c3","L3800-09","in 10mM DMSO","N/A","N/A","Phase 3","Apoptosis related,Autophagy,JAK","JAK/STAT","Momelotinib (CYT387, LM-1149 , CYT11387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3. Momelotinib (CYT387) induces apoptosis and autophagy. Phase 3.",414.46,"1056634-68-4",{"v":74,"d":"74.00"},178.55,"<1","N/A","http://selleckchem.com/products/Cyt387.html","C23H22N6O2","free base","LM-1149 , CYT11387","O=C(NCC#N)C1=CC=C(C=C1)C2=NC(=NC=C2)NC3=CC=C(C=C3)N4CCOCC4",2.857,4,2,6]
["S2226","Idelalisib","d3","L3800-09","in 10mM DMSO","FDA,DMF,EMA,NDC","N/A","Marketed","Autophagy,PI3K","PI3K/Akt/mTOR","Idelalisib (CAL-101, GS-1101) is a selective p110δ inhibitor with IC50 of 2.5 nM in cell-free assays; shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR. Idelalisib also stimulates autophagy.",415.42,"870281-82-6",{"v":83,"d":"83.00"},{"v":199.8,"d":"199.80"},"<1","N/A","http://selleckchem.com/products/CAL-101.html","C22H18FN7O","free base","CAL-101, GS-1101","CCC(NC1=C2N=C[NH]C2=NC=N1)C3=NC4=CC=CC(=C4C(=O)N3C5=CC=CC=C5)F",3.624,5,2,5]
["S2228","Belnacasan (VX-765)","e3","L3800-09","in 10mM DMSO","N/A","N/A","Phase 2","Caspase","Apoptosis","Belnacasan (VX-765) is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM in a cell-free assay. Phase 2.",{"v":509,"d":"509.00"},"273404-37-8",{"v":100,"d":"100.00"},196.46,"<1","N/A","http://selleckchem.com/products/VX-765.html","C24H33ClN4O6","free base","N/A","CCOC1OC(=O)CC1NC(=O)C2CCCN2C(=O)C(NC(=O)C3=CC(=C(N)C=C3)Cl)C(C)(C)C",1.698,6,3,8]
["S2229","Eltrombopag (SB497115) Olamine","f3","L3800-09","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","TpoR","Immunology & Inflammation","Eltrombopag Olamine (SB-497115-GR, Revolade, Promacta,Promacta Olamine) is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR).",564.63,"496775-62-3",{"v":89,"d":"89.00"},157.63,"<1","N/A","http://selleckchem.com/products/Eltrombopag-SB-497115-GR.html","C29H36N6O6","diolamine","SB-497115-GR, Revolade, Promacta,Promacta Olamine","CC1=CC=C(C=C1C)N2N=C(C)C(=N/NC3=CC=CC(=C3O)C4=CC(=CC=C4)C(O)=O)/C2=O.NCCO.NCCO",-0.151,4,6,7]
["S2230","Galunisertib (LY2157299)","g3","L3800-09","in 10mM DMSO","N/A","N/A","Phase 2/3","TGF-beta/Smad","TGF-beta/Smad","Galunisertib (LY2157299) is a potent TGFβ receptor I (TβRI) inhibitor with IC50 of 56 nM in a cell-free assay. Phase 2/3.",369.42,"700874-72-2",{"v":74,"d":"74.00"},200.31,"<1","N/A","http://selleckchem.com/products/ly2157299.html","C22H19N5O","free base","N/A","CC1=CC=CC(=N1)C2=N[N]3CCCC3=C2C4=CC=NC5=C4C=C(C=C5)C(N)=O",3.095,4,1,3]
["S2231","Telatinib","h3","L3800-09","in 10mM DMSO","N/A","N/A","Phase 2","c-Kit,PDGFR,VEGFR","Protein Tyrosine Kinase","Telatinib (BAY 57-9352) is a potent inhibitor of VEGFR2/3, c-Kit and PDGFRα with IC50 of 6 nM/4 nM, 1 nM and 15 nM, respectively. Phase 2.",409.83,"332012-40-5",{"v":82,"d":"82.00"},200.08,"<1","N/A","http://selleckchem.com/products/Telatinib-BAY-57-9352.html","C20H16ClN5O3","free base","BAY 57-9352","CNC(=O)C1=NC=CC(=C1)COC2=NN=C(NC3=CC=C(Cl)C=C3)C4=C2OC=C4",3.861,6,2,6]
["S2233","Esomeprazole sodium","a4","L3800-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","EP9.7;Martindale:The Extra Pharmacopoeia","Marketed","ATPase","Transmembrane Transporters","Esomeprazole Sodium((S)-Omeprazole sodium, (-)-Omeprazole sodium) is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.",{"v":367.4,"d":"367.40"},"161796-78-7",{"v":73,"d":"73.00"},198.69,{"v":73,"d":"73.00"},198.69,"http://selleckchem.com/products/esomeprazole-sodium.html","C17H18N3O3S.Na","Sodium salt","(S)-Omeprazole sodium, (-)-Omeprazole sodium","COC1=CC=C2[N]([Na])C(=NC2=C1)[S](=O)CC3=NC=C(C)C(=C3C)OC",3.008,5,0,5]
["S2235","Volasertib (BI 6727)","b4","L3800-09","in 10mM DMSO","N/A","N/A","Phase 3","Apoptosis related,PLK","Cell Cycle","Volasertib (BI 6727) is a highly potent Plk1 inhibitor with IC50 of 0.87 nM in a cell-free assay. It shows 6- and 65-fold greater selectivity against Plk2 and Plk3. Volasertib induces cell cycle arrest and apoptosis in various cancer cells. Phase 3.",618.81,"755038-65-4",{"v":20,"d":"20.00"},32.32,"<1","N/A","http://selleckchem.com/products/BI6727-Volasertib.html","C34H50N8O3","free base","N/A","CCC1N(C(C)C)C2=C(C=NC(=N2)NC3=CC=C(C=C3OC)C(=O)NC4CCC(CC4)N5CCN(CC5)CC6CC6)N(C)C1=O",4.838,5,2,10]
["S2238","Palomid 529 (P529)","c4","L3800-09","in 10mM DMSO","N/A","N/A","Phase 1","mTOR","PI3K/Akt/mTOR","Palomid 529 (P529, SG 00529) inhibits both the mTORC1 and mTORC2 complexes, reduces phosphorylation of pAktS473, pGSK3βS9, and pS6. Phase 1.",406.43,"914913-88-5",{"v":81,"d":"81.00"},{"v":199.3,"d":"199.30"},"<1","N/A","http://selleckchem.com/products/Palomid-529-P529.html","C24H22O6","free base","SG 00529","COC1=CC=C(COC2=C(OC)C=C3C(=C2)OC(=O)C4=C3C=CC(=C4)C(C)O)C=C1",4.257,5,1,6]
["S2244","AR-42","d4","L3800-09","in 10mM DMSO","N/A","N/A","Phase 1","HDAC","Epigenetics","AR-42 (HDAC-42) is an HDAC inhibitor with IC50 of 30 nM. Phase 1.",312.36,"935881-37-1",{"v":63,"d":"63.00"},201.69,"<1","N/A","http://selleckchem.com/products/AR-42-HDAC-42.html","C18H20N2O3","free base","HDAC-42","CC(C)C(C(=O)NC1=CC=C(C=C1)C(=O)NO)C2=CC=CC=C2",2.834,2,2,5]
["S2246","Abiraterone Acetate (CB7630)","e4","L3800-09","in 10mM DMSO","FDA,DMF,NDC,PMDA","USP42-NF37","Marketed","Androgen Receptor,P450 (e.g. CYP17)","Metabolism","Abiraterone Acetate (CB7630, CB-7630) is an acetate salt form of Abiraterone which is a steroidal cytochrome CYP17 inhibitor with IC50 of 72 nM in a cell-free assay. Abiraterone acetate is an oral androgen biosynthesis inhibitor.",391.55,"154229-18-2",{"v":20,"d":"20.00"},51.08,"<1","N/A","http://www.selleck.cn/products/Abiraterone-Acetate-CB7630.html","C26H33NO2","Acetate","CB7630, CB-7630","CC(=O)OC1CCC2(C)C3CCC4(C)C(CC=C4C5=CC=CN=C5)C3CC=C2C1",4.602,3,0,3]
["S2247","Buparlisib (BKM120)","f4","L3800-09","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,PI3K","PI3K/Akt/mTOR","Buparlisib (BKM120, NVP-BKM120) is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM in cell-free assays, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. Buparlisib induces apoptosis. Phase 2.",410.39,"944396-07-0",{"v":82,"d":"82.00"},199.81,"<1","N/A","http://selleckchem.com/products/BKM-120.html","C18H21F3N6O2","free base","NVP-BKM120","NC1=CC(=C(C=N1)C2=NC(=NC(=C2)N3CCOCC3)N4CCOCC4)C(F)(F)F",2.342,5,1,4]
["S2248","Silmitasertib (CX-4945)","g4","L3800-09","in 10mM DMSO","N/A","N/A","Phase 1/2","Apoptosis related,Autophagy,Casein Kinase","Metabolism","Silmitasertib (CX-4945) is a potent and selective inhibitor of CK2 (casein kinase 2) with IC50 of 1 nM in a cell-free assay, less potent to Flt3, Pim1 and CDK1 (inactive in cell-based assay). Silmitasertib induces autophagy and promotes apoptosis. Phase 1/2.",349.77,"1009820-21-6",{"v":16,"d":"16.00"},45.74,"<1","N/A","http://selleckchem.com/products/cx-4945-silmitasertib.html","C19H12ClN3O2","free base","N/A","OC(=O)C1=CC2=C(C=C1)C3=CN=CC=C3C(=N2)NC4=CC(=CC=C4)Cl",4.157,3,1,3]
["S2250","(-)-Epigallocatechin Gallate","h4","L3800-09","in 10mM DMSO","DMF","N/A","N/A","DNA Methyltransferase,EGFR,Fatty Acid Synthase,HER2,Telomerase","DNA Damage/DNA Repair","(-)-Epigallocatechin Gallate(EGCG) is the main catechin extraction of green tea that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 receptors. ECGG inhibits fatty acid synthase and glutamate dehydrogenase activity.",458.37,"989-51-5",{"v":72,"d":"72.00"},157.08,{"v":23,"d":"23.00"},50.18,"http://selleckchem.com/products/(-)-Epigallocatechin-gallate.html","C22H18O11","free base","EGCG","OC1=CC2=C(CC(OC(=O)C3=CC(=C(O)C(=C3)O)O)C(O2)C4=CC(=C(O)C(=C4)O)O)C(=C1)O",3.097,3,8,4]
["S2256","4-Methylumbelliferone (4-MU)","a5","L3800-09","in 10mM DMSO","CFDA","BP2019;KP Ⅹ;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM.",176.17,"90-33-5",{"v":35,"d":"35.00"},198.67,"<1","N/A","http://selleckchem.com/products/4-Methylumbelliferone(4-MU).html","C10H8O3","free base","N/A","CC1=CC(=O)OC2=C1C=CC(=C2)O",2.104,2,1,0]
["S2258","Esculin","b5","L3800-09","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Others","Others","Esculin (Aesculin) is a glucoside found in horse chestnuts.",340.28,"531-75-9",{"v":68,"d":"68.00"},199.84,{"v":2,"d":"2.00"},5.88,"http://selleckchem.com/products/Aesculin(Esculin).html","C15H16O9","free base","Aesculin","OCC1OC(OC2=C(O)C=C3OC(=O)C=CC3=C2)C(O)C(O)C1O",-0.514,4,5,3]
["S2260","Amygdalin","c5","L3800-09","in 10mM DMSO","NDC","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Amygdalin is a glycoside initially isolated from the seeds of the tree Prunus dulcis, also known as bitter almonds.",457.43,"29883-15-6",{"v":91,"d":"91.00"},198.94,"<1","N/A","http://selleckchem.com/products/Amygdalin.html","C20H27NO11","free base","N/A","OCC1OC(OCC2OC(OC(C#N)C3=CC=CC=C3)C(O)C(O)C2O)C(O)C(O)C1O",-2.403,4,7,7]
["S2261","Andrographolide","d5","L3800-09","in 10mM DMSO","CFDA","BP2019;EP9.2","Phase 2","NF-κB","NF-κB","Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata.",350.45,"5508-58-7",{"v":70,"d":"70.00"},199.74,"<1","N/A","http://selleckchem.com/products/Andrographolide.html","C20H30O5","free base","N/A","CC1(CO)C(O)CCC2(C)C(C\\C=C\\3C(O)COC3=O)C(=C)CCC12",2.056,2,3,3]
["S2262","Apigenin (LY 080400)","e5","L3800-09","in 10mM DMSO","N/A","EP9.2;BP2017","N/A","P450 (e.g. CYP17)","Metabolism","Apigenin (NSC 83244, LY 080400) is a potent P450 inhibitor for CYP2C9 with Ki of 2 μM.",270.24,"520-36-5",{"v":54,"d":"54.00"},199.82,"<1","N/A","http://selleckchem.com/products/Apigenin.html","C15H10O5","free base","NSC 83244","OC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(O)C=C3O",{"v":2.41,"d":"2.410"},2,3,1]
["S2263","Arbutin","f5","L3800-09","in 10mM DMSO","NDC","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Tyrosinase","Proteases","Arbutin (Uva, p-Arbutin, β-Arbutin) is a tyrosinase inhibitor with IC50 of 0.9 mM and 0.7 mM for Monophenolase and Diphenolase, respectively.",272.25,"497-76-7",{"v":55,"d":"55.00"},202.02,{"v":55,"d":"55.00"},202.02,"http://selleckchem.com/products/Arbutin(Uva,-p-Arbutin).html","C12H16O7","free base","Uva,p-Arbutin, β-Arbutin","OCC1OC(OC2=CC=C(O)C=C2)C(O)C(O)C1O",-0.584,2,5,3]
["S2264","Artemether","g5","L3800-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Ph.Int_6th;Martindale:The Extra Pharmacopoeia","Phase 3","ADC Cytotoxin,Anti-infection","Microbiology","Artemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria.",298.37,"71963-77-4",{"v":60,"d":"60.00"},201.09,"<1","N/A","http://selleckchem.com/products/Artemether(SM-224).html","C16H26O5","free base","SM-224, CGP 56696","COC1OC2OC3(C)CCC4C(C)CCC(C1C)C24OO3",2.029,5,0,1]
["S2265","Artesunate (WR-256283)","h5","L3800-09","in 10mM DMSO","DMF,CFDA","Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","N/A","ADC Cytotoxin,STAT","JAK/STAT","Artesunate (WR-256283) is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69. It is a potential inhibitor of STAT-3 and exhibits selective cytotoxicity of cancer cells over normal cells in vitro; A potent inhibitor of EXP1.",384.42,"88495-63-0",{"v":77,"d":"77.00"},{"v":200.3,"d":"200.30"},"<1","N/A","http://selleckchem.com/products/Artesunate.html","C19H28O8","free base","WR-256283","CC1CCC2C(C)C(OC3OC4(C)CCC1C23OO4)OC(=O)CCC(O)=O",1.845,7,0,5]
["S2266","Asiatic Acid","a6","L3800-09","in 10mM DMSO","NDC","N/A","N/A","p38 MAPK","MAPK","Asiatic acid (Dammarolic acid, Asiantic acid) is the aglycone of asiaticoside isolated from the plant Centella asiatica, commonly used in wound healing.",{"v":488.7,"d":"488.70"},"464-92-6",{"v":97,"d":"97.00"},198.49,"<1","N/A","http://selleckchem.com/products/Asiatic-acid.html","C30H48O5","free base","Dammarolic acid, Asiantic acid","CC1CCC2(CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(CO)C5CCC34C)C2C1C)C(O)=O",4.435,1,3,2]
["S2268","Baicalein","b6","L3800-09","in 10mM DMSO","CFDA","N/A","N/A","P450 (e.g. CYP17),PREP","Metabolism","Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor.",270.24,"491-67-8",{"v":54,"d":"54.00"},199.82,"<1","N/A","http://selleckchem.com/products/Baicalein.html","C15H10O5","free base","N/A","OC1=C(O)C(=C2C(=O)C=C(OC2=C1)C3=CC=CC=C3)O",{"v":2.41,"d":"2.410"},2,3,1]
["S2269","Baicalin (NSC-661431)","c6","L3800-09","in 10mM DMSO","CFDA","BP2019;EP9.2","N/A","GABA Receptor,PREP","Neuronal Signaling","Baicalin (NSC-661431) is a known prolyl endopeptidase inhibitor and affects the GABA receptors.",446.36,"21967-41-9",{"v":89,"d":"89.00"},199.39,"<1","N/A","http://selleckchem.com/products/Baicalin.html","C21H18O11","free base","N/A","OC1C(O)C(OC(C1O)C(O)=O)OC2=C(O)C(=C3C(=O)C=C(OC3=C2)C4=CC=CC=C4)O",0.608,5,5,4]
["S2270","Bergenin","d6","L3800-09","in 10mM DMSO","CFDA","N/A","N/A","Others","Others","Bergenin (Cuscutin) is trihydroxybenzoic acid glycoside and the C-glycoside of 4-O-methyl gallic acid.",328.27,"477-90-7",{"v":66,"d":"66.00"},201.05,"<1","N/A","http://selleckchem.com/products/Bergenin-(Cuscutin).html","C14H16O9","free base","Cuscutin","COC1=C(O)C2=C(C=C1O)C(=O)OC3C(O)C(O)C(CO)OC23",-0.849,4,5,2]
["S2271","Berberine chloride (NSC 646666)","e6","L3800-09","in 10mM DMSO","PMDA","BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","N/A","Anti-infection,Apoptosis related,Autophagy,Bcl-2,Caspase,IAP,JNK,p38 MAPK,P450 (e.g. CYP17),PARP,ROS,Topoisomerase","Microbiology","Berberine chloride (NSC 646666, Natural Yellow 18) is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. Berberine chloride decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. Berberine chloride induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. Berberine chloride is a dual topoisomerase I and II inhibitor. Berberine chloride is also a potential autophagy modulator.",371.81,"633-65-8",{"v":40,"d":"40.00"},107.58,"<1","N/A","http://selleckchem.com/products/Berberine-Hydrochloride.html","C20H18NO4.Cl","chloride","Natural Yellow 18 chloride","[Cl-].COC1=CC=C2C=C3C4=C(CC[N+]3=CC2=C1OC)C=C5OCOC5=C4",1.289,4,0,2]
["S2277","Caffeic Acid","f6","L3800-09","in 10mM DMSO","CFDA,NDC","BP2019;EP9.2;CP2005","N/A","Lipoxygenase,TRP Channel","Transmembrane Transporters","Caffeic acid is a hydroxycinnamic acid, a naturally occurring organic compound. Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO).",180.16,"331-39-5",{"v":36,"d":"36.00"},199.82,"<1","N/A","http://selleckchem.com/products/Caffeic-acid.html","C9H8O4","free base","N/A","OC(=O)/C=C/C1=CC=C(O)C(=C1)O",1.443,1,2,2]
["S2280","Chlorogenic Acid","g6","L3800-09","in 10mM DMSO","N/A","USP42-NF37 ;BP2019;EP9.2","Phase 2/3","Others","Others","Chlorogenic acid (NSC 407296, Heriguard) is a hydroxycinnamic acid and a member of a family of naturally occurring organic compounds.",354.31,"327-97-9",{"v":71,"d":"71.00"},200.39,{"v":18,"d":"18.00"},{"v":50.8,"d":"50.80"},"http://selleckchem.com/products/Chlorogenic-acid.html","C16H18O9","free base","NSC 407296, Heriguard","OC1CC(O)(CC(OC(=O)\\C=C\\C2=CC(=C(O)C=C2)O)C1O)C(O)=O",{"v":-0.34,"d":"-0.340"},3,4,5]
["S2282","Cinchonidine","h6","L3800-09","in 10mM DMSO","N/A","USP42-NF37;BP2019;EP9.2","N/A","Anti-infection,Serotonin Transporter","Microbiology","Cinchonidine is an alkaloid used in asymmetric synthesis in organic chemistry.",294.39,"485-71-2",{"v":59,"d":"59.00"},200.41,"<1","N/A","http://selleckchem.com/products/Cinchonidine.html","C19H22N2O","free base","N/A","OC(C1CC2CCN1CC2C=C)C3=CC=NC4=CC=CC=C34",{"v":2.75,"d":"2.750"},1,1,3]
["S2283","Cinchonine(LA40221)","a7","L3800-09","in 10mM DMSO","N/A","USP42-NF37;BP2019;EP9.2","N/A","5-alpha Reductase","Angiogenesis","Cinchonine (LA40221) is an alkaloid and a stereoisomer and pseudo-enantiomer of cinchonidine.",{"v":294.4,"d":"294.40"},"118-10-5",{"v":9,"d":"9.00"},30.57,"N/A","N/A","http://selleckchem.com/products/cinchonine.html","C19H22N2O","free base","N/A","OC(C1CC2CCN1CC2C=C)C3=CC=NC4=CC=CC=C34",{"v":2.75,"d":"2.750"},1,1,3]
["S2284","Colchicine (NSC 757)","b7","L3800-09","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.4;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Microtubule Associated","Cell Cycle","Colchicine (NSC 757, Colchineos, Colchisol, Colcin) is a microtubule polymerization inhibitor with an IC50 of 3 nM.",399.44,"64-86-8",{"v":80,"d":"80.00"},200.28,{"v":80,"d":"80.00"},200.28,"http://selleckchem.com/products/colchicine.html","C22H25NO6","free base","Colchineos, Colchisol, Colcin,NSC 757","COC1=CC=C2C(=CC1=O)C(CCC3=C2C(=C(OC)C(=C3)OC)OC)NC(C)=O",2.044,6,1,5]
["S2286","Cyclosporin A (NSC 290193)","c7","L3800-09","in 10mM DMSO","N/A","N/A","Phase 2","Antineoplastic and Immunosuppressive Antibiotics,Complement System,Immunology & Inflammation related,phosphatase","Immunology & Inflammation","Cyclosporin A (Cyclosporine A, Cyclosporine, Ciclosporin, CsA,NSC 290193) is an immunosuppressive agent, binds to the cyclophilin and then inhibits calcineurin with IC50 of 7 nM in a cell-free assay, widely used in organ transplantation to prevent rejection.",1202.61,"59865-13-3",{"v":100,"d":"100.00"},83.15,"<1","N/A","http://selleckchem.com/products/Cyclosporin-A(Cyclosporine-A).html","C62H111N11O12","free base","Cyclosporine A, Cyclosporine, Ciclosporin, CsA,NSC 290193","CCC1NC(=O)C(C(O)C(C)C\\C=C\\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C",4.333,11,5,15]
["S2287","Cytisine","d7","L3800-09","in 10mM DMSO","NDC,HMA","Martindale:The Extra Pharmacopoeia","Phase 3","AChR","Neuronal Signaling","Cytisine (Baphitoxine, Sophorine) is a nicotinic acetylcholine receptor agonist.",190.24,"485-35-8",{"v":38,"d":"38.00"},199.75,{"v":38,"d":"38.00"},199.75,"http://selleckchem.com/products/Cytisine(Baphitoxine,-Sophorine).html","C11H14N2O","free base","Baphitoxine,Sophorine","O=C1C=CC=C2C3CNCC(C3)CN12",-0.338,1,1,0]
["S2289","Daidzin","e7","L3800-09","in 10mM DMSO","CFDA","BP2019;EP9.2","N/A","Dehydrogenase","Metabolism","Daidzin (Daidzoside, Daidzein 7-O-glucoside, Daidzein 7-glucoside), a natural organic compound in the class of phytochemicals known as isoflavones, is a potent and selective inhibitor of human mitochondrial aldehyde dehydrogenase and inhibits ALDH-I selectively (Ki=20 nM); at least 500 times less effective against ALDH-Ⅱ, the cytosolic isozyme (Ki=10 μM).",416.38,"552-66-9",{"v":83,"d":"83.00"},199.34,"<1","N/A","http://selleckchem.com/products/Daidzin.html","C21H20O9","Free Base","Daidzoside, Daidzein 7-O-glucoside, Daidzein 7-glucoside","OCC1OC(OC2=CC3=C(C=C2)C(=O)C(=CO3)C4=CC=C(O)C=C4)C(O)C(O)C1O",0.452,4,5,4]
["S2290","Dihydroartemisinin (DHA)","f7","L3800-09","in 10mM DMSO","CFDA","N/A","N/A","Apoptosis related,Autophagy,NF-κB","NF-κB","Dihydroartemisinin (DHA, Dihydroqinghaosu, β-Dihydroartemisinin, Artenimol) is a semi-synthetic derivative of artemisinin and isolated from the traditional Chinese herb Artemisia annua. Dihydroartemisinin induces autophagy and apoptosis by suppressing NF-κB activation.",284.35,"71939-50-9",{"v":56,"d":"56.00"},196.94,"<1","N/A","http://selleckchem.com/products/Dihydroartemisinin(DHA).html","C15H24O5","free base","Dihydroqinghaosu, β-Dihydroartemisinin, Artenimol","CC1CCC2C(C)C(O)OC3OC4(C)CCC1C23OO4",1.621,4,0,0]
["S2293","DL-Carnitine HCl","g7","L3800-09","in 10mM DMSO","DMF","N/A","N/A","Others","Others","DL-Carnitine HCl is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine.",197.66,"461-05-2",{"v":40,"d":"40.00"},202.37,{"v":40,"d":"40.00"},202.37,"http://selleckchem.com/products/DL-Carnitine-hydrochloride.html","C7H15NO3.HCl","Hydrochloride","N/A","[Cl-].C[N+](C)(C)CC(O)CC(O)=O",{"v":-4.49,"d":"-4.490"},1,1,4]
["S2295","Emodin","h7","L3800-09","in 10mM DMSO","N/A","BP2018;EP9.2","N/A","Dehydrogenase","Metabolism","Emodin is a purgative resin, 6-methyl-1,3,8-trihydroxyanthraquinone, from rhubarb, the buckthorn and Japanese Knotweed (Fallopia japonica).",270.24,"518-82-1",{"v":54,"d":"54.00"},199.82,"<1","N/A","http://selleckchem.com/products/Emodin.html","C15H10O5","free base","N/A","CC1=CC2=C(C(=C1)O)C(=O)C3=C(C=C(O)C=C3O)C2=O",2.568,2,3,0]
["S2296","Enoxolone","a8","L3800-09","in 10mM DMSO","CFDA","BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Dehydrogenase","Metabolism","Enoxolone (Glycyrrhetin) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.",470.68,"471-53-4",{"v":94,"d":"94.00"},199.71,"<1","N/A","http://selleckchem.com/products/Enoxolone(Glycyrrhetin).html","C30H46O4","free base","Glycyrrhetin","CC1(C)C(O)CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O",5.656,2,1,1]
["S2298","Fisetin","b8","L3800-09","in 10mM DMSO","N/A","N/A","Phase 3","Sirtuin","Epigenetics","Fisetin (Fustel) is a potent sirtuin activating compound (STAC) and an agent that modulates sirtuins.",286.24,"528-48-3",{"v":57,"d":"57.00"},199.13,"<1","N/A","http://selleckchem.com/products/Fisetin(Fustel).html","C15H10O6","free base","N/A","OC1=CC2=C(C=C1)C(=O)C(=C(O2)C3=CC(=C(O)C=C3)O)O",1.872,2,4,1]
["S2299","Formononetin","c8","L3800-09","in 10mM DMSO","N/A","BP2019","N/A","Others","Endocrinology & Hormones","Formononetin (Formononetol, Biochanin B) is a phytoestrogen from the root of Astragalus membranaceus and an O-methylated isoflavone.",268.26,"485-72-3",{"v":54,"d":"54.00"},{"v":201.3,"d":"201.30"},"<1","N/A","http://selleckchem.com/products/Formononetin(Formononetol).html","C16H12O4","free base","Formononetol, Biochanin B","COC1=CC=C(C=C1)C2=COC3=C(C=CC(=C3)O)C2=O",2.608,3,1,2]
["S2300","Ferulic Acid","d8","L3800-09","in 10mM DMSO","N/A","USP42-NF37;BP2019;EP9.1","N/A","FGFR","Angiogenesis","Ferulic Acid (Fumalic) is a hydroxycinnamic acid and a type of organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong. Ferulic acid is a novel fibroblast growth factor receptor (FGFR) inhibitor with IC50s of 3.78 μM and 12.5 μM for FGFR1 and FGFR2, respectively.",194.19,"1135-24-6",{"v":39,"d":"39.00"},200.83,"<1","N/A","http://selleckchem.com/products/Fumalic-acid(Ferulic-acid).html","C10H10O4","free base","Fumalic Acid","COC1=CC(=CC=C1O)\\C=C\\C(O)=O",1.669,2,1,3]
["S2302","Glycyrrhizin (NSC 167409)","e8","L3800-09","in 10mM DMSO","CFDA","N/A","Marketed","Dehydrogenase,High-mobility Group,MAO","Metabolism","Glycyrrhizin (NSC 167409, Glycyrrhizic Acid) is a direct HMGB1(high mobility group box 1) inhibitor that inhibits HMGB1-dependent inflammatory molecule expression and oxidative stress; modulates P38 and P-JNK but not p-ERK signalling; Also inhibits 11 beta-hydroxysteroid dehydrogenase and monoamine oxidase (MAO).",822.93,"1405-86-3",{"v":100,"d":"100.00"},121.52,"<1","N/A","http://selleckchem.com/products/Glycyrrhizic-acid.html","C42H62O16","free base","N/A","CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O)OC6OC(C(O)C(O)C6OC7OC(C(O)C(O)C7O)C(O)=O)C(O)=O",2.417,8,5,7]
["S2303","Gossypol Acetate","f8","L3800-09","in 10mM DMSO","N/A","N/A","Phase 2","Dehydrogenase","Metabolism","Gossypol Acetate (Gossypol Acetic acid, Pogosin, AT101) is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes.",578.61,"12542-36-8",{"v":100,"d":"100.00"},172.83,"<1","N/A","https://www.selleckchem.com/products/gossypol-acetate.html","C32H34O10","Acetate","Gossypol Acetic acid, Pogosin, AT101","CC(C)C1=C2C=C(C)C(=C(O)C2=C(C=O)C(=C1O)O)C3=C(O)C4=C(C=C3C)C(=C(O)C(=C4C=O)O)C(C)C.CC(O)=O",6.388,3,6,5]
["S2304","Gramine","g8","L3800-09","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","ADC Cytotoxin,AdipoR,Adrenergic Receptor","Metabolism","Gramine (Donaxine) is a natural indole alkaloid isolated from giant reed, acts as an active adiponectin receptor (AdipoR) agonist, with IC50 of 3.2 µM and 4.2 µM for AdipoR2 and AdipoR1, respectively. Gramine is also a human and mouse β2-Adrenergic receptor (β2-AR) agonist.",174.24,"87-52-5",{"v":35,"d":"35.00"},200.87,"<1","N/A","http://selleckchem.com/products/Gramine.html","C11H14N2","free base","N/A","CN(C)CC1=C[NH]C2=C1C=CC=C2",2.197,0,1,2]
["S2305","Grape Seed Extract","h8","L3800-09","in 10mM DMSO","N/A","N/A","Phase 3","Others","Others","Grape Seed Extract are industrial derivatives from whole grape seeds that have a great concentration of vitamin E, flavonoids, linoleic acid, and OPCs.","N/A","84929-27-1",{"v":94,"d":"94.00"},{"v":10,"d":"10.00"},"<1","N/A","http://selleckchem.com/products/Grape-Seed-Extract.html","N/A","Polyphenols","N/A","N/A",{"v":0,"d":"0.000"},0,0,0]
["S2308","Hesperetin","a9","L3800-09","in 10mM DMSO","CFDA","EP10.4, USP43-NF38","N/A","Histamine Receptor,TGF-beta/Smad","TGF-beta/Smad","Hesperetin is a bioflavonoid and, to be more specific, a flavanone.",302.27,"520-33-2",{"v":60,"d":"60.00"},{"v":198.5,"d":"198.50"},"<1","N/A","http://selleckchem.com/products/Hesperetin.html","C16H14O6","free base","N/A","COC1=CC=C(C=C1O)C2CC(=O)C3=C(O)C=C(O)C=C3O2",2.357,3,3,2]
["S2309","Hesperidin","b9","L3800-09","in 10mM DMSO","DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Phase 2","Others","Others","Hesperidin (Cirantin) is a flavanone glycoside found abundantly in citrus fruits.",610.56,"520-26-3",{"v":100,"d":"100.00"},163.78,"<1","N/A","http://selleckchem.com/products/Hesperidin.html","C28H34O15","free base","Cirantin","COC1=CC=C(C=C1O)C2CC(=O)C3=C(O)C=C(OC4OC(COC5OC(C)C(O)C(O)C5O)C(O)C(O)C4O)C=C3O2",-0.431,7,8,7]
["S2310","Honokiol (NSC 293100)","c9","L3800-09","in 10mM DMSO","N/A","BP2019;EP9.2","Phase 2","Akt,Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,Autophagy,HCV,MEK","PI3K/Akt/mTOR","Honokiol (NSC 293100) is the active principle of magnolia extract that inhibits Akt-phosphorylation and promotes ERK1/2 phosphorylation. Honokiol causes G0/G1 phase arrest, induces apoptosis, and autophagy via the ROS/ERK1/2 signaling pathway. Honokiol inhibits hepatitis C virus (HCV) infection. Phase 3.",266.33,"35354-74-6",{"v":53,"d":"53.00"},{"v":199,"d":"199.00"},"<1","N/A","http://selleckchem.com/products/Honokiol.html","C18H18O2","free base","N/A","OC1=C(CC=C)C=C(C=C1)C2=CC(=CC=C2O)CC=C",{"v":4.88,"d":"4.880"},0,2,5]
["S2311","Hyodeoxycholic acid (HDCA)","d9","L3800-09","in 10mM DMSO","CFDA","N/A","N/A","GPCR19","GPCR & G Protein","Hyodeoxycholic (HDCA, NSC 60672) acid is a secondary bile acid, one of the metabolic byproducts of intestinal bacteria.",392.57,"83-49-8",{"v":78,"d":"78.00"},198.69,"<1","N/A","http://selleckchem.com/products/Hyodeoxycholic-acid(HDCA).html","C24H40O4","free base","NSC 60672","CC(CCC(O)=O)C1CCC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C",4.014,1,2,4]
["S2312","Icariin","e9","L3800-09","in 10mM DMSO","N/A","N/A","Phase 3","PDE","Metabolism","Icariin is a cGMP-specific PDE5 inhibitor with IC50 of 0.432 μM, 167-fold more selective for PDE5 than PDE4.",676.66,"489-32-7",{"v":50,"d":"50.00"},73.89,"<1","N/A","http://selleckchem.com/products/Icariin.html","C33H40O15","free base","N/A","COC1=CC=C(C=C1)C2=C(OC3OC(C)C(O)C(O)C3O)C(=O)C4=C(O2)C(=C(OC5OC(CO)C(O)C(O)C5O)C=C4O)CC=C(C)C",0.983,7,8,9]
["S2313","Indole-3-carbinol","f9","L3800-09","in 10mM DMSO","N/A","N/A","Phase 3","NF-κB","NF-κB","Indole-3-carbinol is produced by the breakdown of the glucosinolate glucobrassicin, which can be found at relatively high levels in cruciferous vegetables. Indole-3-carbinol suppresses NF-κB and IκBα kinase activation.",147.18,"700-06-1",{"v":29,"d":"29.00"},197.04,{"v":7,"d":"7.00"},47.56,"http://selleckchem.com/products/Indole-3-carbinol.html","C9H9NO","free base","N/A","OCC1=C[NH]C2=C1C=CC=C2",1.518,0,2,1]
["S2314","Kaempferol (NSC 407289)","g9","L3800-09","in 10mM DMSO","N/A","USP42-NF37;BP2019;EP9.2","N/A","Estrogen/progestogen Receptor,Fatty Acid Synthase","Endocrinology & Hormones","Kaempferol (NSC 407289, Robigenin), a natural flavonol, functions as an ERRα and ERRγ inverse agonist. It inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase.",286.23,"520-18-3",{"v":57,"d":"57.00"},199.14,"<1","N/A","http://selleckchem.com/products/Kaempferol.html","C15H10O6","free base","Robigenin","OC1=CC=C(C=C1)C2=C(O)C(=O)C3=C(O)C=C(O)C=C3O2",1.872,2,4,1]
["S2316","Kinetin","h9","L3800-09","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Kinetin (6-Furfuryladenine) is a type of cytokinin, a class of plant hormone that promotes cell division.",215.21,"525-79-1",{"v":8,"d":"8.00"},37.17,"<1","N/A","http://selleckchem.com/products/Kinetin(6-Furfuryladenine).html","C10H9N5O","free base","6-Furfuryladenine","C(NC1=NC=NC2=C1[NH]C=N2)C3=CC=CO3",0.875,4,2,3]
["S2317","L-(+)-Rhamnose Monohydrate","a10","L3800-09","in 10mM DMSO","N/A","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","L(+)-Rhamnose (Rham) is a naturally-occurring deoxy sugar that is found primarily in plants and some bacteria.",182.17,"10030-85-0",{"v":36,"d":"36.00"},197.62,{"v":36,"d":"36.00"},197.62,"http://selleckchem.com/products/l-positive-rotation-rhamnose-monohydrate.html","C6H12O5.H2O","Monohydrate","N/A","O.CC1OC(O)C(O)C(O)C1O",-1.833,1,3,0]
["S2318","Lappaconitine","b10","L3800-09","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","N/A","Sodium Channel","Transmembrane Transporters","Lappaconitine (LC) is a natural diterpenoid alkaloid (DTA), acting as a human heart sodium channel blocker and possessing a wide range of biological activities, including anti-arrhythmic, anti-inflammatory, antioxidative, anticancer, epileptiform etc.",{"v":584.7,"d":"584.70"},"32854-75-4",{"v":16,"d":"16.00"},27.36,"N/A","N/A","http://selleckchem.com/products/lappaconitine.html","C32H44N2O8","free base","N/A","CCN1CC2(CCC(OC)C34C2CC(C13)C5(O)CC(OC)C6CC4C5(O)C6OC)OC(=O)C7=CC=CC=C7NC(C)=O",0.029,6,1,8]
["S2320","Luteolin","c10","L3800-09","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","ADC Cytotoxin,PDE","Metabolism","Luteolin (Luteoline, Luteolol, Digitoflavone) is a flavonoid found in Terminalia chebula, which is a non-selective phisphodiesterase PDE inhibitor for PDE1-5 with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM, respectively.",286.24,"491-70-3",{"v":57,"d":"57.00"},199.13,"<1","N/A","https://www.selleckchem.com/products/luteolin.html","C15H10O6","free base","Luteoline, Luteolol, Digitoflavone","OC1=CC(=C2C(=O)C=C(OC2=C1)C3=CC=C(O)C(=C3)O)O",2.168,2,4,1]
["S2321","Magnolol","d10","L3800-09","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Fungal,NF-κB","NF-κB","Magnolol (NSC 293099) is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. It can block TNF-α-induced NF-KB activation.",266.33,"528-43-8",{"v":53,"d":"53.00"},{"v":199,"d":"199.00"},"<1","N/A","http://selleckchem.com/products/Magnolol(2,2-Bichavicol).html","C18H18O2","free base","NSC 293099","OC1=C(C=C(CC=C)C=C1)C2=CC(=CC=C2O)CC=C",{"v":4.88,"d":"4.880"},0,2,5]
["S2322","(+)-Matrine","e10","L3800-09","in 10mM DMSO","CFDA","N/A","N/A","Opioid Receptor","Neuronal Signaling","Matrine((+)-Matrine) is an alkaloid found in plants from the Sophora family, which has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist.",248.36,"519-02-8",{"v":49,"d":"49.00"},197.29,{"v":11,"d":"11.00"},44.29,"http://selleckchem.com/products/matrine.html","C15H24N2O","free base","N/A","O=C1CCCC2C3CCCN4CCCC(CN12)C34",1.417,1,0,0]
["S2323","Methyl-Hesperidin","f10","L3800-09","in 10mM DMSO","N/A","N/A","Phase 4","Akt,PKC","PI3K/Akt/mTOR","Methyl Hesperidin is a flavanone glycoside (flavonoid) (C28H34O15) found abundantly in citrus fruits. Its aglycone form is called hesperetin.",624.59,"11013-97-1",{"v":100,"d":"100.00"},155.62,{"v":100,"d":"100.00"},155.62,"http://selleckchem.com/products/Methyl-Hesperidin.html","C29H36O15","free base","N/A","COC1=CC=C(C=C1O)C2CC(=O)C3=C(OC)C=C(OC4OC(COC5OC(C)C(O)C(O)C5O)C(O)C(O)C4O)C=C3O2",{"v":-0.79,"d":"-0.790"},7,8,7]
["S2325","Morin Hydrate","g10","L3800-09","in 10mM DMSO","N/A","USP42-NF37","N/A","Others","Others","Morin hydrate (Aurantica) is a flavonoid isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava).",320.25,"6202-27-3",{"v":64,"d":"64.00"},199.84,"<1","N/A","https://www.selleckchem.com/products/Morin-hydrate.html","C15H10O7.H2O","Hydrate","Aurantica","O.OC1=CC=C(C(=C1)O)C2=C(O)C(=O)C3=C(O)C=C(O)C=C3O2",1.423,2,5,1]
["S2328","Nalidixic acid","h10","L3800-09","in 10mM DMSO","FDA,DMF,CFDA,PMDA","USP42-NF37;BP2019;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Selection Antibiotics for Transfected Cell,Topoisomerase","DNA Damage/DNA Repair","Nalidixic acid (NSC-82174) is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.",232.24,"389-08-2",{"v":6,"d":"6.00"},25.84,"<1","N/A","http://selleckchem.com/products/Nalidixic-acid(NegGram).html","C12H12N2O3","free base","NSC-82174","CCN1C=C(C(O)=O)C(=O)C2=C1N=C(C)C=C2",1.176,3,0,2]
["S2329","Naringin","a11","L3800-09","in 10mM DMSO","N/A","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","P450 (e.g. CYP17)","Metabolism","Naringin (Naringoside) is a flavanone glycoside, which exerts a variety of pharmacological effects such as antioxidant activity, blood lipid lowering, anticancer activity, and inhibition of cytochrome P450 enzymes.",580.53,"10236-47-2",{"v":100,"d":"100.00"},172.26,"<1","N/A","http://selleckchem.com/products/Naringin(Naringoside).html","C27H32O14","free base","Naringoside","CC1OC(OC2C(O)C(O)C(CO)OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC=C(O)C=C5)O)C(O)C(O)C1O",-0.415,6,8,6]
["S2331","Neohesperidin Dihydrochalcone (Nhdc)","b11","L3800-09","in 10mM DMSO","N/A","EP9.1;BP2017","N/A","Others","Others","Neohesperidin dihydrochalcone(Nhdc, NCI-c60764), sometimes abbreviated to neohesperidin DC or simply NHDC, is an artificial sweetener derived from citrus.",612.58,"20702-77-6",{"v":100,"d":"100.00"},163.24,"<1","N/A","http://selleckchem.com/products/Neohesperidin-dihydrochalcone(Nhdc).html","C28H36O15","free base","NCI-c60764","COC1=C(O)C=C(CCC(=O)C2=C(O)C=C(OC3OC(CO)C(O)C(O)C3OC4OC(C)C(O)C(O)C4O)C=C2O)C=C1",-0.048,6,9,10]
["S2332","Neohesperidin","c11","L3800-09","in 10mM DMSO","N/A","EP9.1;BP2017","N/A","ROS","Immunology & Inflammation","Neohesperidin (NSC 31048), a flavanone glycoside found in citrus fruits, is an antioxidant agent., Neohesperidin (NSC 31048) 是一种抗氧化剂，在1,1-diphenyl-2-picryldydrazyl（DPPH）自由基清除测定中，IC50为22.31 μg/ml。",610.56,"13241-33-3",{"v":122,"d":"122.00"},199.82,"<1","N/A","http://selleckchem.com/products/Neohesperidin.html","C28H34O15","free base","NSC 31048","COC1=CC(=CC(=C1)C2CC(=O)C3=C(O)C=C(OC4OC(CO)C(O)C(O)C4OC5OC(C)C(O)C(O)C5O)C=C3O2)O",-0.431,7,8,7]
["S2334","Oleanolic Acid","d11","L3800-09","in 10mM DMSO","CFDA","BP2019;EP9.2","N/A","Antiviral","Microbiology","Oleanolic Acid (Caryophyllin) is a non-toxic, hepatoprotective triterpenoid found in Phytolacca Americana, which exerts antitumor and antiviral properties.",{"v":456.7,"d":"456.70"},"508-02-1",{"v":21,"d":"21.00"},45.98,"<1","N/A","http://selleckchem.com/products/Oleanolic-Acid(Caryophyllin).html","C30H48O3","free base","Caryophyllin","CC1(C)CC(C2CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC34C)C2C1)C(O)=O",6.282,1,1,1]
["S2335","Oridonin (NSC-250682)","e11","L3800-09","in 10mM DMSO","N/A","N/A","Phase 4","Akt,Bacterial","PI3K/Akt/mTOR","Oridonin (Isodonol, Rubescenin, NSC-250682), a diterpenoid purified from Rabdosia rubescens, is a traditional agent with antitumor, anti-bacterial and anti-inflammatory effects. Oridonin inhibits AKT1 and AKT2 kinase activity with IC50 of 8.4 μM and 8.9 μM, respectively.",364.43,"28957-04-2",{"v":72,"d":"72.00"},197.57,"<1","N/A","http://selleckchem.com/products/Oridonin(Isodonol).html","C20H28O6","free base","Isodonol, Rubescenin","CC1(C)CCC(O)C23COC(O)(C(O)C12)C45C(O)C(CCC34)C(=C)C5=O",{"v":0.2,"d":"0.200"},2,3,0]
["S2336","Orotic acid (6-Carboxyuracil)","f11","L3800-09","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia","Phase 2","Others","Others","Orotic acid(6-Carboxyuracil) is a heterocyclic compound and an acid.",{"v":156.1,"d":"156.10"},"65-86-1",{"v":2,"d":"2.00"},12.81,"<1","N/A","http://selleckchem.com/products/Orotic-acid(6-Carboxyuracil).html","C5H4N2O4","free base","N/A","OC(=O)C1=CC(=O)NC(=O)N1",-1.152,3,2,1]
["S2337","Osthole","g11","L3800-09","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Others","Others","Osthol is an O-methylated coumarin, which is found in the plants such as Cnidium monnieri, Angelica archangelica and Angelica pubescens.",244.29,"484-12-8",{"v":49,"d":"49.00"},200.58,"<1","N/A","http://selleckchem.com/products/Osthole(Osthol).html","C15H16O3","free base","Osthol","COC1=CC=C2C=CC(=O)OC2=C1CC=C(C)C",{"v":3.74,"d":"3.740"},3,0,3]
["S2338","Oxymatrine","h11","L3800-09","in 10mM DMSO","CFDA","CP2005","N/A","Immunology & Inflammation related","TGF-beta/Smad","Oxymatrine (Matrine N-oxide) is a quinolizidine alkaloid extracted from the root of Sophora flavescens with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. It is used for the treatment of viral hepatitis, cancer, viral myocarditis, gastrointestinal hemorrhage and skin diseases.",264.36,"16837-52-8",{"v":53,"d":"53.00"},200.48,{"v":53,"d":"53.00"},200.48,"http://selleckchem.com/products/Oxymatrine(Matrine-N-oxide).html","C15H24N2O2","free base","Matrine N-oxide","[O-][N+]12CCCC3CN4C(CCCC4=O)C(CCC1)C23",{"v":0.61,"d":"0.610"},1,0,0]
["S2339","Paeonol","a2","L3800-10","in 10mM DMSO","CFDA","BP2019;EP9.2;CP2005","N/A","MAO","Metabolism","Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 μM.",166.17,"552-41-0",{"v":33,"d":"33.00"},198.59,"<1","N/A","http://selleckchem.com/products/Paeonol(Peonol).html","C9H10O3","free base","Peonol","COC1=CC(=C(C=C1)C(C)=O)O",1.311,2,1,2]
["S2341","(-)-Parthenolide","b2","L3800-10","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","HDAC,MDM2/MDMX,NF-κB,p53","NF-κB","(-)-Parthenolide, an inhibitor of the Nuclear Factor-κB Pathway, specifically depletes HDAC1 protein without affecting other class I/II HDACs; Also promotes the ubiquitination of MDM2 and activates p53 cellular functions.",248.32,"20554-84-1",{"v":49,"d":"49.00"},197.33,"<1","N/A","http://selleckchem.com/products/Parthenolide((-)-Parthenolide).html","C15H20O3","free base","N/A","CC/1=C\\CCC2(C)OC2C3OC(=O)C(=C)C3CC1",2.923,3,0,0]
["S2344","Piperine","c2","L3800-10","in 10mM DMSO","NDC","BP2019;EP9.2","Marketed","P450 (e.g. CYP17)","Metabolism","Piperine (1-Piperoylpiperidine) is the alkaloid responsible for the pungency of black pepper and long pepper, which has also been used in some forms of traditional medicine and as an insecticide.",285.34,"94-62-2",{"v":57,"d":"57.00"},199.76,"<1","N/A","http://selleckchem.com/products/Piperine(1-Piperoylpiperidine).html","C17H19NO3","free base","1-Piperoylpiperidine","O=C(\\C=C\\C=C\\C1=CC2=C(OCO2)C=C1)N3CCCCC3",2.864,3,0,3]
["S2346","Puerarin","d2","L3800-10","in 10mM DMSO","CFDA","BP2019;EP9.2;CP2005","N/A","5-HT Receptor","Neuronal Signaling","Puerarin (Kakonein), an isoflavones found in the root of Radix puerariae, is a 5-HT2C receptor and benzodiazepine site antagonist.",416.38,"3681-99-0",{"v":86,"d":"86.00"},206.54,"<1","N/A","http://selleckchem.com/products/Puerarin(Kakonein).html","C21H20O9","free base","Kakonein","OCC1OC(OC2=C(O)C=CC3=C2OC=C(C3=O)C4=CC=C(O)C=C4)C(O)C(O)C1O",{"v":0.21,"d":"0.210"},4,6,4]
["S2347","Quercetin Dihydrate","e2","L3800-10","in 10mM DMSO","N/A","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Phase 2/3","PI3K,Sirtuin","PI3K/Akt/mTOR","Quercetin (Sophoretin), a polyphenolic flavonoid found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine, is utilized in many different cultures for their nervous system and anticancer effects. Quercetin (dihydrate), a natural flavonoid, is a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC50s of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively.",338.27,"6151-25-3",{"v":67,"d":"67.00"},198.07,"<1","N/A","http://selleckchem.com/products/Quercetin-dihydrate(Sophoretin).html","C15H10O7.2H2O","Dihydrate","Sophoretin","O.O.OC1=CC(=C2C(=O)C(=C(OC2=C1)C3=CC=C(O)C(=C3)O)O)O",1.216,2,5,1]
["S2348","Rotenone (Barbasco)","f2","L3800-10","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Apoptosis related,Mitochondrial Metabolism,Mitophagy,NADPH-oxidase,ROS","Immunology & Inflammation","Rotenone (Barbasco, Dactinol, Paraderil, Rotenon, Rotocide) is a botanical insecticide that is an inhibitor of mitochondrial electron transport. Rotenone inhibits NADH/DB oxidoreductase and NADH oxidase with IC50 of 28.8 nM and 5.1 nM, respectively. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production.",394.42,"83-79-4",{"v":78,"d":"78.00"},197.76,"N/A","N/A","http://selleckchem.com/products/rotenone-barbasco.html","C23H22O6","free base","Barbasco, Dactinol, Paraderil, Rotenon, Rotocide","COC1=CC2=C(C=C1OC)C3C(CO2)OC4=C(C=CC5=C4CC(O5)C(C)=C)C3=O",{"v":3.93,"d":"3.930"},6,0,3]
["S2349","Rutaecarpine","g2","L3800-10","in 10mM DMSO","N/A","EP10.4","N/A","COX","Neuronal Signaling","Rutaecarpine (Rutecarpine) is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs; a new class of COX-2 inhibitor.",287.32,"84-26-4",{"v":24,"d":"24.00"},83.53,"<1","N/A","http://selleckchem.com/products/Rutaecarpine(Rutecarpine).html","C18H13N3O","free base","Rutecarpine","O=C1N2CCC3=C([NH]C4=C3C=CC=C4)C2=NC5=C1C=CC=C5",3.359,2,1,0]
["S2350","Rutin","h2","L3800-10","in 10mM DMSO","DMF,CFDA,NDC","USP42-NF37;EP8.8;CP2005","Phase 2/3","ADC Cytotoxin,Immunology & Inflammation related","Immunology & Inflammation","Rutin (Rutoside), a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human.",610.52,"153-18-4",{"v":100,"d":"100.00"},163.79,"<1","N/A","http://selleckchem.com/products/Rutin(Rutoside).html","C27H30O16","free base","Rutoside","CC1OC(OCC2OC(OC3=C(OC4=C(C(=CC(=C4)O)O)C3=O)C5=CC(=C(O)C=C5)O)C(O)C(O)C2O)C(O)C(O)C1O",-1.158,6,10,6]
["S2351","Salicin","a3","L3800-10","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","COX","Neuronal Signaling","Salicin (Salicoside, Salicine) is a phenol β-glycosid produced from willow bark that shows anti-inflammatory effects. It is a natural, non-selective COX-1 and COX-2 inhibitor.",286.28,"138-52-3",{"v":57,"d":"57.00"},199.11,{"v":24,"d":"24.00"},83.83,"http://selleckchem.com/products/Salicin(Salicoside,-Salicine).html","C13H18O7","free base","Salicoside,Salicine","OCC1OC(OC2=CC=CC=C2CO)C(O)C(O)C1O",-0.947,2,5,4]
["S2354","Sclareol","b3","L3800-10","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Others","Others","Sclareol, a labdane-type diterpene isolated from clary sage (Salvia sclarea), exerts growth inhibition and cytotoxic activity against a variety of human cancer cell lines.",{"v":308.5,"d":"308.50"},"515-03-7",{"v":61,"d":"61.00"},197.73,"<1","N/A","http://selleckchem.com/products/Sclareol.html","C20H36O2","free base","N/A","CC1(C)CCCC2(C)C1CCC(C)(O)C2CCC(C)(O)C=C",{"v":4.27,"d":"4.270"},0,0,4]
["S2357","Silibinin (NSC 651520)","c3","L3800-10","in 10mM DMSO","CFDA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Silibinin (NSC 651520, Silybin, Silibinin A, Silymarin I, Flavobin), the main flavonoid extracted from the milk thistle Silybum marianum, displays hepatoprotective properties in acute and chronic liver injury.",482.44,"22888-70-6",{"v":96,"d":"96.00"},198.99,"<1","N/A","http://selleckchem.com/products/Silibinin(Silybin).html","C25H22O10","free base","Silybin, Silibinin A, Silymarin I, Flavobin","COC1=CC(=CC=C1O)C2OC3=CC(=CC=C3OC2CO)C4OC5=CC(=CC(=C5C(=O)C4O)O)O",2.592,5,5,4]
["S2358","Silymarin","d3","L3800-10","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","Phase 4","Antioxidant","Angiogenesis","Silymarin (Silybin B), a polyphenolic flavonoid extracted from the seeds of Silybum marianum or milk thistle, is used in the prevention and treatment of liver diseases and primary liver cancer.",482.44,"65666-07-1",{"v":96,"d":"96.00"},198.99,"<1","N/A","http://selleckchem.com/products/Silymarin(Silybin-B).html","C25H22O10","free base","Silybin B","COC1=CC(=CC=C1O)C2OC3=CC=C(C=C3OC2CO)C4OC5=C(C(=CC(=C5)O)O)C(=O)C4O",2.592,5,5,4]
["S2359","Sinomenine","e3","L3800-10","in 10mM DMSO","N/A","BP2019;EP9.2;CP2005","N/A","Immunology & Inflammation related","Immunology & Inflammation","Sinomenine (Cucoline, Kukoline), a pure alkaloid extracted from the chinese medical plant Sinomenium acutum, is used for the treatment of rheumatism and arthritis.",329.39,"115-53-7",{"v":65,"d":"65.00"},197.33,{"v":65,"d":"65.00"},197.33,"http://selleckchem.com/products/Sinomenine(Cucoline).html","C19H23NO4","free base","Cucoline, Kukoline","COC1=CC2C3CC4=C(C(=C(OC)C=C4)O)C2(CCN3C)CC1=O",1.674,3,1,2]
["S2362","Synephrine","f3","L3800-10","in 10mM DMSO","NDC","N/A","N/A","Adrenergic Receptor","GPCR & G Protein","Synephrine (Oxedrine), a natural protoalkaloid in the extract of bitter orange and other citrus species, is commonly used for weight loss.",167.21,"94-07-5",{"v":33,"d":"33.00"},197.36,"<1","N/A","http://selleckchem.com/products/Synephrine(Oxedrine).html","C9H13NO2","free base","Oxedrine","CNCC(O)C1=CC=C(O)C=C1",0.615,0,3,3]
["S2364","Tanshinone I","g3","L3800-10","in 10mM DMSO","CFDA","N/A","N/A","Phospholipase (e.g. PLA)","Metabolism","Tanshinone I, an active principle isolated from Salvia miltiorrhiza (Danshen), is structurally similar to tanshinone IIA and may possess similar cytotoxic effects on tumor cells.",276.29,"568-73-0",{"v":23,"d":"23.00"},83.25,"<1","N/A","http://selleckchem.com/products/Tanshinone-I.html","C18H12O3","free base","N/A","CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C(C)C=CC=C34",4.084,3,0,0]
["S2365","Tanshinone IIA","h3","L3800-10","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Lipase","Metabolism","Tanshinone IIA (Tanshinone B) is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae Radix, a widely prescribed traditional herbal medicine that is used to treat cardiovascular and inflammatory diseases; A natural monoacylglycerol lipase inhibitor.",294.34,"568-72-9",{"v":5,"d":"5.00"},16.99,"<1","N/A","http://selleckchem.com/products/Tanshinone-IIA(Tanshinone-B).html","C19H18O3","free base","Tanshinone B","CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C",{"v":4.66,"d":"4.660"},3,0,0]
["S2366","Taxifolin (Dihydroquercetin)","a4","L3800-10","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","VEGFR","Angiogenesis","Taxifolin, type I inhibitor for VEGFR-2 kinase, is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.",304.25,"480-18-2",{"v":60,"d":"60.00"},197.21,"<1","N/A","http://selleckchem.com/products/Taxifolin(Dihydroquercetin).html","C15H12O7","free base","N/A","OC1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(O)C=C3)O",1.479,2,5,1]
["S2369","Troxerutin","b4","L3800-10","in 10mM DMSO","DMF,CFDA,NDC","EP9.3;BP2019;Martindale:The Extra Pharmacopoeia","N/A","NLR,ROS","Immunology & Inflammation","Troxerutin, a natural bioflavonoid isolated from Sophora japonica, has been reported to have many benefits and medicinal properties. Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation.",742.68,"7085-55-4",{"v":100,"d":"100.00"},134.65,{"v":100,"d":"100.00"},134.65,"http://selleckchem.com/products/Troxerutin.html","C33H42O19","free base","N/A","CC1OC(OCC2OC(OC3=C(OC4=CC(=CC(=C4C3=O)O)OCCO)C5=CC(=C(OCCO)C=C5)OCCO)C(O)C(O)C2O)C(O)C(O)C1O",{"v":-2.1,"d":"-2.100"},9,10,15]
["S2370","Ursolic Acid","c4","L3800-10","in 10mM DMSO","N/A","BP2019;EP9.2;CP2005","N/A","Others","Others","Ursolic acid (NSC 167406, NSC-4060, Prunol, Urson, Malol) is a pentacyclic triterpene acid, used in cosmetics.",{"v":456.7,"d":"456.70"},"77-52-1",{"v":91,"d":"91.00"},199.26,"<1","N/A","http://selleckchem.com/products/Ursolic-acid(Malol).html","C30H48O3","free base","NSC 167406, NSC-4060, Prunol, Urson, Malol","CC1CC(C2CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC34C)C2C1C)C(O)=O",6.327,1,1,1]
["S2373","Yohimbine HCl","d4","L3800-10","in 10mM DMSO","DMF","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Adrenergic Receptor","Neuronal Signaling","Yohimbine (Antagonil) has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.",{"v":390.9,"d":"390.90"},"65-19-0",{"v":12,"d":"12.00"},{"v":30.7,"d":"30.70"},"<1","N/A","http://selleckchem.com/products/Yohimbine-hydrochloride(Antagonil).html","C21H26N2O3.HCl","Hydrochloride","Antagonil","Cl.COC(=O)C1C(O)CCC2CN3CCC4=C([NH]C5=C4C=CC=C5)C3CC12",3.204,2,2,2]
["S2374","5-hydroxytryptophan (5-HTP)","e4","L3800-10","in 10mM DMSO","DMF,NDC","N/A","Phase 4","Others","Others","5-Hydroxytryptophan (5-HTP, NSC-92523), also known as oxitriptan (INN), is a naturally occurring amino acid and chemical precursor for the treatment of depression.",220.22,"56-69-9",{"v":44,"d":"44.00"},{"v":199.8,"d":"199.80"},{"v":4,"d":"4.00"},18.16,"http://selleckchem.com/products/5-hydroxytryptophan(5-HTP).html","C11H12N2O3","free base","NSC-92523","NC(CC1=C[NH]C2=CC=C(O)C=C12)C(O)=O",-1.554,1,3,3]
["S2375","Aloin","f4","L3800-10","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia;CP2005","N/A","Tyrosinase","Proteases","Aloin (Barbaloin, Barbalin), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.",418.39,"1415-73-2",{"v":83,"d":"83.00"},198.38,{"v":83,"d":"83.00"},198.38,"http://selleckchem.com/products/Aloin(Barbaloin).html","C21H22O9","free base","Barbaloin, Barbalin","OCC1OC(C(O)C(O)C1O)C2C3=C(C(=CC=C3)O)C(=O)C4=C2C=C(CO)C=C4O",-0.404,2,7,3]
["S2376","Ammonium Glycyrrhizinate","g4","L3800-10","in 10mM DMSO","CFDA","N/A","N/A","Dehydrogenase,High-mobility Group","Metabolism","Ammonium Glycyrrhizinate (AMGZ, Glycyram, Glycyrrhizin ammonium salt, Glycyrrhizic acid ammonium salt) is a unique product from Licorice root with a very high sweetness. Ammonium glycyrrhizinate is a direct inhibitor of HMGB1 with anti-inflammatory, anti-tumor, anti-diabetic activities. Ammonium Glycyrrhizinate inhibits growth and cytopathology of several unrelated DNA and RNA viruses. Ammonium Glycyrrhizinate also inhibits both hepatic delta 4-5-reductase and 11 beta-hydroxysteroid dehydrogenase.",839.96,"1407-03-0",{"v":168,"d":"168.00"},200.01,{"v":5,"d":"5.00"},5.95,"http://selleckchem.com/products/Ammonium-Glycyrrhizinate(AMGZ).html","C42H62O16.NH3","Glycyrrhizic acid salt","AMGZ, Glycyram, Glycyrrhizin ammonium salt, Glycyrrhizic acid ammonium salt","N.CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O)OC6OC(C(O)C(O)C6OC7OC(C(O)C(O)C7O)C(O)=O)C(O)=O",-0.915,8,5,7]
["S2378","Butylscopolamine Bromide","h4","L3800-10","in 10mM DMSO","CFDA","N/A","N/A","AChR","Neuronal Signaling","Butylscopolamine Bromide (Scopolamine Butylbromide,(-)-Scopolamine butylbromide, Hyoscine butylbromide), is a peripherally acting antimuscarinic, anticholinergic agent used as an abdominal-specific antispasmodic.",440.37,"149-64-4",{"v":88,"d":"88.00"},199.83,{"v":88,"d":"88.00"},199.83,"http://selleckchem.com/products/butylscopolamine-bromide.html","C21H30NO4.Br","Bromide","Scopolamine Butylbromide,(-)-Scopolamine butylbromide, Hyoscine butylbromide","[Br-].CCCC[N+]1(C)C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",{"v":-1.62,"d":"-1.620"},3,1,8]
["S2379","Dioscin","a5","L3800-10","in 10mM DMSO","CFDA","N/A","N/A","Others","Others","Dioscin (Collettiside III, Saponin) is a saponin extracted and isolated from Polygonatum Zanlanscianense Pamp, showing antitumor activities.",869.04,"19057-60-4",{"v":100,"d":"100.00"},115.07,"<1","N/A","http://selleckchem.com/products/Dioscin(Collettiside-III).html","C45H72O16","free base","Collettiside III, Saponin","CC1CCC2(OC1)OC3CC4C5CC=C6CC(CCC6(C)C5CCC4(C)C3C2C)OC7OC(CO)C(OC8OC(C)C(O)C(O)C8O)C(O)C7OC9OC(C)C(O)C(O)C9O",1.169,8,8,7]
["S2380","Diosmetin","b5","L3800-10","in 10mM DMSO","NDC","N/A","N/A","P450 (e.g. CYP17)","Metabolism","Diosmetin (Luteolin 4-methyl ether) is a bioflavonoid found in spearmint, oregano, and many other plants.",300.26,"520-34-3",{"v":60,"d":"60.00"},199.83,"<1","N/A","http://selleckchem.com/products/Diosmetin(Luteolin-4-methyl-ether).html","C16H12O6","free base","Luteolin 4-methyl ether","COC1=CC=C(C=C1O)C2=CC(=O)C3=C(O)C=C(O)C=C3O2",2.394,3,3,2]
["S2381","D-Mannitol","c5","L3800-10","in 10mM DMSO","DMF","USP42-NF37;JP17;BP2018;IP2010","N/A","Others","Others","D-Mannitol is an osmotic diuretic agent and a weak renal vasodilator.",182.17,"69-65-8",{"v":36,"d":"36.00"},197.62,{"v":36,"d":"36.00"},197.62,"http://selleckchem.com/products/D-Mannitol(Osmitrol).html","C6H14O6","free base","Osmitrol","OCC(O)C(O)C(O)C(O)CO",-2.941,0,6,5]
["S2382","Evodiamine","d5","L3800-10","in 10mM DMSO","N/A","EP9.2","N/A","NF-κB","NF-κB","Evodiamine (Isoevodiamine), an alkaloid extract from the fruit of Evodiae Fructus exhibits antitumor activities against the human tumor cells. It is shown to inhibit NF-kB activation through suppression of IkB kinase activity.",303.36,"518-17-2",{"v":12,"d":"12.00"},39.56,"<1","N/A","http://www.selleck.cn/products/Evodiamine(Isoevodiamine).html","C19H17N3O","Free Base","Isoevodiamine","CN1C2N(CCC3=C2[NH]C4=CC=CC=C34)C(=O)C5=C1C=CC=C5",3.673,1,1,0]
["S2383","Gastrodin","e5","L3800-10","in 10mM DMSO","CFDA","CP2005","Phase 4","Immunology & Inflammation related","Immunology & Inflammation","Gastrodin (Gastrodine), an anti-inflammatory polyphenol extracted from Chinese natural herbal Gastrodia elata Blume., benefits neurodegenerative diseases.",286.28,"62499-27-8",{"v":50,"d":"50.00"},174.65,"<1","N/A","http://selleckchem.com/products/Gastrodin(Gastrodine).html","C13H18O7","free base","Gastrodine","OCC1OC(OC2=CC=C(CO)C=C2)C(O)C(O)C1O",-0.947,2,5,4]
["S2384","Hematoxylin","f5","L3800-10","in 10mM DMSO","N/A","USP42-NF37;IP2010","N/A","Dyes","Others","Hematoxylin (Hydroxybrazilin) is a compound that forms strongly colored complexes with certain metal ions, notably Fe(III) and Al(III) salts and a kind of stain in histology.",302.28,"517-28-2",{"v":61,"d":"61.00"},{"v":201.8,"d":"201.80"},{"v":61,"d":"61.00"},{"v":201.8,"d":"201.80"},"http://selleckchem.com/products/Hematoxylin(Hydroxybrazilin).html","C16H14O6","free base","Hydroxybrazilin","OC1=CC2=C(C=C1O)C3C4=C(OCC3(O)C2)C(=C(O)C=C4)O",1.691,1,4,0]
["S2386","Indirubin (NSC 105327)","g5","L3800-10","in 10mM DMSO","CFDA","BP2019;EP9.2;CP2005","N/A","GSK-3","PI3K/Akt/mTOR","Indirubin (NSC 105327) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 μM and 0.6 μM.",262.26,"479-41-4",{"v":53,"d":"53.00"},202.09,"<1","N/A","http://selleckchem.com/products/Indirubin.html","C16H10N2O2","free base","NSC 105327","O=C1NC2=CC=CC=C2\\C1=C3/NC4=C(C=CC=C4)C3=O",1.876,2,2,0]
["S2387","Lappaconite HBr","h5","L3800-10","in 10mM DMSO","CFDA","N/A","N/A","ADC Cytotoxin,Immunology & Inflammation related","Immunology & Inflammation","Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects.",665.61,"97792-45-5",{"v":28,"d":"28.00"},42.07,"<1","N/A","http://selleckchem.com/products/Lappaconite-Hydrobromide.html","C32H44N2O8.HBr","Hydrobromide","N/A","Br.CCN1CC2(CCC(OC)C34C2CC(C13)C5(O)CC(OC)C6CC4C5(O)C6OC)OC(=O)C7=C(NC(C)=O)C=CC=C7",{"v":0.52,"d":"0.520"},6,1,8]
["S2388","L-carnitine","a6","L3800-10","in 10mM DMSO","DMF,NDC","N/A","Marketed","Others","Others","L-carnitine (Levocarnitine,Carnitor, vitamin BT, Karnitin,L(-)-Carnitine) is constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.",{"v":161.2,"d":"161.20"},"541-15-1",{"v":12,"d":"12.00"},74.44,{"v":32,"d":"32.00"},198.51,"http://selleckchem.com/products/L-carnitine(Levocarnitine).html","C7H15NO3","quaternary-N  salt","Levocarnitine,Carnitor, vitamin BT, Karnitin,L(-)-Carnitine","C[N+](C)(C)CC(O)CC([O-])=O",{"v":-3.29,"d":"-3.290"},0,1,4]
["S2389","Naringin Dihydrochalcone","b6","L3800-10","in 10mM DMSO","N/A","BP2019;EP9.2;CP2005;Martindale:The Extra Pharmacopoeia","N/A","P450 (e.g. CYP17)","Metabolism","Naringin Dihydrochalcone(Naringin DC) is a new-style sweetening agent and an artificial sweetener derived from naringin and also an inhibitor of CYP enzymes.",582.55,"18916-17-1",{"v":100,"d":"100.00"},171.66,"<1","N/A","http://selleckchem.com/products/Naringin-Dihydrochalcone(Naringin-DC).html","C27H34O14","free base","N/A","CC1OC(OC2C(O)C(O)C(CO)OC2OC3=CC(=C(C(=O)CCC4=CC=C(O)C=C4)C(=C3)O)O)C(O)C(O)C1O",-0.032,5,9,9]
["S2390","Polydatin","c6","L3800-10","in 10mM DMSO","NDC","BP2019;EP9.2;CP2005","N/A","Phospholipase (e.g. PLA)","Metabolism","Polydatin (Piceid) is a crystal component extracted from the root stem of perennial herbage Polygonum Cuspidatum Sieb.et Zucc.",390.38,"65914-17-2",{"v":78,"d":"78.00"},199.81,"<1","N/A","http://selleckchem.com/products/Polydatin(Piceid).html","C20H22O8","free base","Piceid","OCC1OC(OC2=CC(=CC(=C2)\\C=C\\C3=CC=C(O)C=C3)O)C(O)C(O)C1O",{"v":1.16,"d":"1.160"},2,6,5]
["S2391","Quercetin (NSC 9221)","d6","L3800-10","in 10mM DMSO","DMF,NDC","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Phase 2/3","Apoptosis related,Autophagy,Mitophagy,PI3K,PKC,Sirtuin,Src","Epigenetics","Quercetin (NSC 9221, Sophoretin, C.I. 75720), a natural flavonoid present in vegetables, fruit and wine, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4-5.4 μM. Quercetin induces mitophagy, apoptosis and protective autophagy. Phase 4.",302.24,"117-39-5",{"v":61,"d":"61.00"},201.83,"<1","N/A","http://selleckchem.com/products/Quercetin(Sophoretin).html","C15H10O7","Free Base","Sophoretin, C.I. 75720","OC1=CC(=C2C(=O)C(=C(OC2=C1)C3=CC=C(O)C(=C3)O)O)O",{"v":1.63,"d":"1.630"},2,5,1]
["S2393","Sorbitol","e6","L3800-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;EP9.8;BP2019;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","Others","Others","Sorbitol (Glucitol) is a sugar alcohol and a sugar substitute.",182.17,"50-70-4",{"v":36,"d":"36.00"},197.62,{"v":36,"d":"36.00"},197.62,"http://selleckchem.com/products/Sorbitol(Glucitol).html","C6H14O6","free base","Glucitol","OCC(O)C(O)C(O)C(O)CO",-2.941,0,6,5]
["S2394","Naringenin","f6","L3800-10","in 10mM DMSO","N/A","N/A","Phase 1","P450 (e.g. CYP17)","Metabolism","Naringenin (NSC 34875, S-Dihydrogenistein, NSC 11855, Salipurol) is a natural predominant flavanone derived from plant food, which is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, and immune system modulator.",272.25,"480-41-1",{"v":54,"d":"54.00"},198.35,"<1","N/A","http://selleckchem.com/products/naringenin.html","C15H12O5","free base","NSC 34875, S-Dihydrogenistein, NSC 11855, Salipurol","OC1=CC=C(C=C1)C2CC(=O)C3=C(O)C=C(O)C=C3O2",2.373,2,3,1]
["S2396","Salidroside","g6","L3800-10","in 10mM DMSO","N/A","CP2005","N/A","Mitophagy,mTOR,PREP","PI3K/Akt/mTOR","Salidroside (Rhodioloside), a phenylpropanoid glycoside isolated from Rhodiola rosea, has been reported to have a broad spectrum of pharmacological properties. Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.",{"v":300.3,"d":"300.30"},"10338-51-9",{"v":60,"d":"60.00"},{"v":199.8,"d":"199.80"},{"v":60,"d":"60.00"},{"v":199.8,"d":"199.80"},"http://selleckchem.com/products/Salidroside-Rhodioloside.html","C14H20O7","free base","Rhodioloside","OCC1OC(OCCC2=CC=C(O)C=C2)C(O)C(O)C1O",-0.443,2,5,5]
["S2397","Palmatine chloride","h6","L3800-10","in 10mM DMSO","N/A","BP2019","N/A","Calcium Channel","Neuronal Signaling","Palmatine hydrochloride (Palmatine chloride (6CI,7CI); Fibrauretin) is a hydrochloride salt of palmatine which is a protoberberine alkaloid.",387.86,"10605-02-4",{"v":77,"d":"77.00"},198.53,{"v":5,"d":"5.00"},12.89,"http://selleckchem.com/products/Palmatine-chloride.html","C21H22NO4.Cl","Chloride","N/A","[Cl-].COC1=CC=C2C=C3C4=C(CC[N+]3=CC2=C1OC)C=C(OC)C(=C4)OC",1.488,4,0,4]
["S2399","Dihydromyricetin","a7","L3800-10","in 10mM DMSO","N/A","N/A","Phase 2","GABA Receptor,ROS","Neuronal Signaling","Dihydromyricetin (Ampelopsin, Ampeloptin) is a natural antioxidant flavonoid from Ampelopsis grossedentata.",320.25,"27200-12-0",{"v":64,"d":"64.00"},199.84,"<1","N/A","http://selleckchem.com/products/Dihydromyricetin-Ampeloptin.html","C15H12O8","free base","Ampeloptin","OC1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(O)C(=C3)O)O",1.237,2,6,1]
["S2401","Sodium Danshensu","b7","L3800-10","in 10mM DMSO","N/A","CP2005","N/A","P450 (e.g. CYP17)","Metabolism","Sodium Danshensu is a mono sodium of danshensu, which is a natural phenolic acid of caffeic acid derivatives isolated from Salvia miltiorrhiza.",220.15,"67920-52-9",{"v":7,"d":"7.00"},{"v":31.8,"d":"31.80"},{"v":2,"d":"2.00"},9.08,"http://selleckchem.com/products/Sodium-Danshensu.html","C9H9O5.Na","Sodium Salt","N/A","[Na+].OC(CC1=CC(=C(O)C=C1)O)C([O-])=O",-0.795,0,3,3]
["S2403","Tetrandrine (NSC-77037)","c7","L3800-10","in 10mM DMSO","CFDA","EP8.8,BP2017","Preregistration","Calcium Channel","Transmembrane Transporters","Tetrandrine (NSC-77037, Fanchinine, d-Tetrandrine), a bis-benzylisoquinoline alkaloid derived from Stephania tetrandra, is a calcium channel blocker.",622.75,"518-34-3",{"v":7,"d":"7.00"},11.24,"<1","N/A","http://www.selleck.cn/products/Tetrandrine-Fanchinine.html","C38H42N2O6","Free Base","Fanchinine, d-Tetrandrine","COC1=CC=C2CC3N(C)CCC4=CC(=C(OC)C(=C34)OC5=C(OC)C=C6CCN(C)C(CC7=CC=C(OC1=C2)C=C7)C6=C5)OC",7.218,6,0,4]
["S2407","Curcumol","d7","L3800-10","in 10mM DMSO","N/A","N/A","Phase 3","JAK","JAK/STAT","Curcumol is a pure monomer isolated from Rhizoma Curcumaeis with antitumor activities.",236.35,"4871-97-0",{"v":47,"d":"47.00"},198.86,"<1","N/A","http://selleckchem.com/products/Curcumol.html","C15H24O2","free base","N/A","CC(C)C1CC23OC1(O)CC(=C)C2CCC3C",2.786,1,0,1]
["S2410","Paeoniflorin (NSC 178886)","f7","L3800-10","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","COX,HIF","Immunology & Inflammation","Paeoniflorin (NSC 178886,Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin reduces COX-2 expression. Paeoniflorin alleviates liver fibrosis by inhibiting HIF-1α through mTOR-dependent pathway.",480.46,"23180-57-6",{"v":96,"d":"96.00"},199.81,{"v":96,"d":"96.00"},199.81,"http://selleckchem.com/products/paeoniflorin.html","C23H28O11","free base","NSC 178886,Peoniflorin","CC12CC3(O)OC(O1)C4(COC(=O)C5=CC=CC=C5)C3CC24OC6OC(CO)C(O)C(O)C6O",-1.283,6,4,7]
["S2411","Geniposide","g7","L3800-10","in 10mM DMSO","N/A","BP2019;EP9.2;CP2005","N/A","Immunology & Inflammation related","Immunology & Inflammation","Geniposide is an iridoid glycoside isolated from the fruit of Gardenia jasminoides Ellis.",388.37,"24512-63-8",{"v":78,"d":"78.00"},200.84,{"v":78,"d":"78.00"},200.84,"http://selleckchem.com/products/geniposide.html","C17H24O10","free base","N/A","COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C3C1CC=C3CO",-2.066,5,5,6]
["S2412","Genipin","h7","L3800-10","in 10mM DMSO","N/A","N/A","Phase 3","Apoptosis related","Apoptosis","Genipin((+)-Genipin) is an active aglycone derived from an iridoid glycoside called geniposide, which is found in the fruit of Gardenia jasminoides Ellis.",226.23,"6902-77-8",{"v":45,"d":"45.00"},198.91,"<1","N/A","http://selleckchem.com/products/genipin.html","C11H14O5","free base","(+)-Genipin","COC(=O)C1=COC(O)C2C1CC=C2CO",-0.319,3,1,3]
["S2422","Ipriflavone (Osteofix)","b8","L3800-10","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Ipriflavone (7-Isopropoxyisoflavon) is used to inhibit bone resorption.",280.32,"35212-22-7",{"v":56,"d":"56.00"},199.77,"<1","N/A","http://selleckchem.com/products/ipriflavone.html","C18H16O3","free base","N/A","CC(C)OC1=CC=C2C(=C1)OC=C(C2=O)C3=CC=CC=C3",3.576,3,0,3]
["S2423","(S)-10-Hydroxycamptothecin","c8","L3800-10","in 10mM DMSO","DMF","N/A","N/A","Topoisomerase","DNA Damage/DNA Repair","(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor with potent anti-tumor activity.",364.35,"19685-09-7",{"v":8,"d":"8.00"},21.96,"<1","N/A","http://selleckchem.com/products/10-hydroxycamptothecin.html","C20H16N2O5","free base","10-HCPT","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=CC5=CC(=CC=C5N=C34)O)C2=O",1.504,4,1,1]
["S2425","Apocynin (NSC 2146)","d8","L3800-10","in 10mM DMSO","N/A","N/A","Phase 1","NADPH-oxidase","Immunology & Inflammation","Apocynin (NSC 2146, Acetovanillone, NSC 209524) is a selective NADPH-oxidase inhibitor with IC50 of 10 μM.",166.17,"498-02-2",{"v":33,"d":"33.00"},198.59,"<1","N/A","http://selleckchem.com/products/apocynin-acetovanillone.html","C9H10O3","free base","Acetovanillone, NSC 209524","COC1=C(O)C=CC(=C1)C(C)=O",1.311,2,1,2]
["S2437","Rotundine","e8","L3800-10","in 10mM DMSO","CFDA","N/A","N/A","Dopamine Receptor","Neuronal Signaling","Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.",355.43,"483-14-7",{"v":8,"d":"8.00"},22.51,"<1","N/A","http://selleckchem.com/products/rotundine.html","C21H25NO4","free base","L-tetrahydropalmatine, L-THP","COC1=CC2=C(C=C1OC)C3CC4=CC=C(OC)C(=C4CN3CC2)OC",3.599,4,0,4]
["S2438","Synephrine HCl","f8","L3800-10","in 10mM DMSO","NDC","N/A","N/A","Adrenergic Receptor","Neuronal Signaling","SynephrineHCl (Oxedrine, p-Synephrine) is a sympathomimetic α-adrenergic receptor (AR) agonist.",203.67,"5985-28-4",{"v":14,"d":"14.00"},68.74,{"v":41,"d":"41.00"},201.31,"http://selleckchem.com/products/synephrine-hcl.html","C9H13NO2.HCl","Hydrochloride","N/A","Cl.CNCC(O)C1=CC=C(O)C=C1",0.997,0,3,3]
["S2439","Guanosine","g8","L3800-10","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond.",283.24,"118-00-3",{"v":56,"d":"56.00"},197.71,"<1","N/A","http://selleckchem.com/products/guanosine.html","C10H13N5O5","free base","N/A","NC1=NC2=C(N=C[N]2C3OC(CO)C(O)C3O)C(=O)N1",{"v":-2.38,"d":"-2.380"},4,5,2]
["S2442","Inosine","h8","L3800-10","in 10mM DMSO","DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;CP2005;Martindale:The Extra Pharmacopoeia","Phase 2","Others","Others","Inosine (NSC 20262, INO 495) is a nucleoside that is formed when hypoxanthine is attached to a ribose ring via a β-N9-glycosidic bond.",268.23,"58-63-9",{"v":53,"d":"53.00"},197.59,{"v":47,"d":"47.00"},175.22,"http://selleckchem.com/products/inosine.html","C10H12N4O5","free base","NSC 20262, INO 495","OCC1OC(C(O)C1O)[N]2C=NC3=C2N=CNC3=O",-2.249,4,4,2]
["S2443","Tolbutamide (HLS 831)","a9","L3800-10","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Potassium Channel","Transmembrane Transporters","Tolbutamide (HLS 831) is an inhibitor of potassium channel, used for type II diabetes.",270.35,"64-77-7",{"v":54,"d":"54.00"},199.74,"<1","N/A","http://selleckchem.com/products/tolbutamide.html","C12H18N2O3S","free base","HLS 831","CCCCNC(=O)N[S](=O)(=O)C1=CC=C(C)C=C1",2.336,3,2,5]
["S2446","Levosimendan","b9","L3800-10","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia","Marketed","Calcium Channel","Transmembrane Transporters","Levosimendan(OR1259,OR1855,Simsndan) is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC), provides treatment for heart failure.",280.28,"141505-33-1",{"v":56,"d":"56.00"},{"v":199.8,"d":"199.80"},"<1","N/A","http://selleckchem.com/products/levosimendan.html","C14H12N6O","free base","OR1259,OR1855,Simsndan","CC1CC(=O)NN=C1C2=CC=C(NN=C(C#N)C#N)C=C2",1.486,3,2,3]
["S2450","Equol","c9","L3800-10","in 10mM DMSO","NDC","N/A","Phase 2","Estrogen/progestogen Receptor","Endocrinology & Hormones","Equol ,a metabolite of soybeans, is an important isoflavone in humans，specifically binds to 5α-DHT, has a modest affinity for recombinant estrogen receptor ERβ. Phase 2.",242.27,"531-95-3",{"v":48,"d":"48.00"},198.13,"<1","N/A","http://selleckchem.com/products/equol.html","C15H14O3","free base","N/A","OC1=CC=C(C=C1)C2COC3=CC(=CC=C3C2)O",3.211,1,2,1]
["S2451","Amantadine HCl","d9","L3800-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Dopamine Receptor","Neuronal Signaling","Amantadine HCl (1-adamantanamine) is used to treat or prevent infections of the respiratory tract caused by a certain virus.",{"v":187.7,"d":"187.70"},"665-66-7",{"v":38,"d":"38.00"},202.45,{"v":38,"d":"38.00"},202.45,"http://selleckchem.com/products/Amantadine-hydrochloride(Symmetrel).html","C10H17N.HCl","Hydrochloride","1-adamantanamine HCl","Cl.N[C]12CC3[CH2][CH](C[CH]([CH2]3)C1)C2",1.877,0,1,0]
["S2452","Amfebutamone (Bupropion) HCl","e9","L3800-10","in 10mM DMSO","CFDA","N/A","Marketed","AChR,Dopamine Receptor","Neuronal Signaling","Amfebutamone (Bupropion) HCl(Wellbutrin) is a selective norepinephrine-dopamine reuptake inhibitor with IC50 of 6.5 and 3.4 μM for the reuptake of dopamine and norepinephrine, respectively.",{"v":276.2,"d":"276.20"},"31677-93-7",{"v":8,"d":"8.00"},28.96,"<1","N/A","http://selleckchem.com/products/Amfebutamone-hydrochloride(Bupropion).html","C13H18ClNO.HCl","Hydrochloride","Wellbutrin","Cl.CC(NC(C)(C)C)C(=O)C1=CC=CC(=C1)Cl",3.501,1,1,4]
["S2454","Bupivacaine HCl","f9","L3800-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Sodium Channel","Transmembrane Transporters","Bupivacaine HCl binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, used for treating cardiac arrhythmias.",324.89,"18010-40-7",{"v":65,"d":"65.00"},200.07,{"v":23,"d":"23.00"},70.79,"http://selleckchem.com/products/Bupivacaine-hydrochloride(Marcain).html","C18H28N2O.HCl","Hydrochloride","N/A","Cl.CCCCN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",4.692,1,1,5]
["S2455","Bethanechol chloride","g9","L3800-10","in 10mM DMSO","FDA,DMF,NDC,PMDA","USP42-NF37;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Phase 2","AChR","Neuronal Signaling","Bethanechol chloride(Myocholine,Urecholine) is a selective muscarinic receptor agonist without any effect on nicotinic receptors.",196.68,"590-63-6",{"v":39,"d":"39.00"},198.29,{"v":39,"d":"39.00"},198.29,"http://selleckchem.com/products/Carbamyl-beta-methylcholine-chloride(Bethanechol-chloride).html","C7H17N2O2.Cl","quaternary-N Chloride salt","Myocholine,Urecholine","[Cl-].CC(C[N+](C)(C)C)OC(N)=O",-3.702,2,1,4]
["S2456","Chlorpromazine HCl","h9","L3800-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Dopamine Receptor,Potassium Channel","Neuronal Signaling","Chlorpromazine HCl (Sonazine) is a dopamine and potassium channel inhibitor with IC50 of 6.1 and 16 μM for inward-rectifying K+ currents and time-independent outward currents.",355.33,"69-09-0",{"v":71,"d":"71.00"},199.81,{"v":71,"d":"71.00"},199.81,"http://selleckchem.com/products/Chlorpromazine-hydrochloride(Sonazine).html","C17H19ClN2S.HCl","Hydrochloride","Sonazine","Cl.CN(C)CCCN1C2=C(SC3=C1C=C(Cl)C=C3)C=CC=C2",5.121,0,0,4]
["S2457","Clindamycin HCl","a10","L3800-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37 ;EP9.3;BP2019;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Bacterial","Microbiology","Clindamycin HCl inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.",461.44,"21462-39-5",{"v":92,"d":"92.00"},199.38,{"v":92,"d":"92.00"},199.38,"http://selleckchem.com/products/Clindamycin-hydrochloride(Dalacin).html","C18H33ClN2O5S.HCl","Hydrochloride","N/A","Cl.CCCC1CC(N(C)C1)C(=O)NC(C(C)Cl)C2OC(SC)C(O)C(O)C2O",1.659,2,4,7]
["S2458","Clonidine HCl","b10","L3800-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor,Autophagy","Neuronal Signaling","Clonidine HCl(Kapvay) is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg.",{"v":266.5,"d":"266.50"},"4205-91-8",{"v":53,"d":"53.00"},198.87,{"v":53,"d":"53.00"},198.87,"http://selleckchem.com/products/Clonidine-hydrochloride(Catapres).html","C9H9Cl2N3.HCl","Hydrochloride","Kapvay","Cl.ClC1=C(NC2=NCCN2)C(=CC=C1)Cl",2.736,1,2,2]
["S2459","Clozapine","c10","L3800-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Phase 4","5-HT Receptor","Neuronal Signaling","Clozapine (HF 1854, LX 100-129) is an atypical antipsychotic drug by acting as a 5-HT antagonist, used in the treatment of schizophrenia.",326.82,"5786-21-0",{"v":65,"d":"65.00"},198.89,"<1","N/A","http://selleckchem.com/products/Clozapine(Clozaril).html","C18H19ClN4","free base","HF 1854, LX 100-129","CN1CCN(CC1)C2=NC3=C(NC4=C2C=CC=C4)C=CC(=C3)Cl",3.422,1,1,1]
["S2460","Pramipexole","d10","L3800-10","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Dopamine Receptor","Neuronal Signaling","Pramipexole (SND 919,Mirapexin,Sifrol,Mirapex) is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.",211.33,"104632-26-0",{"v":42,"d":"42.00"},198.74,"<1","N/A","http://selleckchem.com/products/Pramipexole-Mirapex.html","C10H17N3S","Free Base","SND 919,Mirapexin,Sifrol,Mirapex","CCCNC1CCC2=C(C1)SC(=N2)N",1.383,1,2,3]
["S2461","Domperidone","e10","L3800-10","in 10mM DMSO","DMF,CFDA,PMDA,HMA","BP2019;EP9.2;KP Ⅹ;JP17;IP2010;CP2005;Martindale:The Extra Pharmacopoeia","Marketed","Dopamine Receptor","Neuronal Signaling","Domperidone is an oral dopamine D2 receptor antagonist, used to treat nausea and vomiting.",425.91,"57808-66-9",{"v":48,"d":"48.00"},{"v":112.7,"d":"112.70"},"<1","N/A","http://selleckchem.com/products/Domperidone(Motilium).html","C22H24ClN5O2","free base","N/A","ClC1=CC2=C(C=C1)N(C3CCN(CCCN4C(=O)NC5=C4C=CC=C5)CC3)C(=O)N2",2.453,2,2,5]
["S2466","Estriol","f10","L3800-10","in 10mM DMSO","DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.5;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estriol (NSC-12169) is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.",288.39,"50-27-1",{"v":57,"d":"57.00"},197.65,"<1","N/A","http://selleckchem.com/products/Estriol(Oestriol).html","C18H24O3","free base","NSC-12169","CC12CCC3C(CCC4=CC(=CC=C34)O)C1CC(O)C2O",2.871,0,3,0]
["S2467","Famciclovir","g10","L3800-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia;CP2005","Marketed","Antiviral","Microbiology","Famciclovir (BRL-42810) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.",321.34,"104227-87-4",{"v":64,"d":"64.00"},199.17,{"v":64,"d":"64.00"},199.17,"http://selleckchem.com/products/Famciclovir(Famvir).html","C14H19N5O4","free base","BRL-42810","CC(=O)OCC(CC[N]1C=NC2=CN=C(N)N=C12)COC(C)=O",-0.294,7,1,9]
["S2468","Fenbendazole","h10","L3800-10","in 10mM DMSO","DMF","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Parasite","Microbiology","Fenbendazole(Fenbendazol,Phenbendasol) is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL.",299.35,"43210-67-9",{"v":4,"d":"4.00"},13.36,"<1","N/A","http://selleckchem.com/products/Fenbendazole(Panacur).html","C15H13N3O2S","free base","Fenbendazol,Phenbendasol","COC(=O)NC1=NC2=C([NH]1)C=C(SC3=CC=CC=C3)C=C2",3.769,3,2,4]
["S2470","Fluocinolone Acetonide","a11","L3800-10","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Glucocorticoid Receptor","Endocrinology & Hormones","Fluocinolone Acetonide (Flucort-N) is a corticosteroid that binds to the cytosolic glucocorticoid receptor.",{"v":452.5,"d":"452.50"},"67-73-2",{"v":90,"d":"90.00"},{"v":198.9,"d":"198.90"},"<1","N/A","http://selleckchem.com/products/Fluocinolone-acetonide(Flucort-N).html","C24H30F2O6","free base","Flucort-N","CC1(C)OC2CC3C4CC(F)C5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(O1)C(=O)CO",0.995,4,2,2]
["S2471","Gallamine Triethiodide","b11","L3800-10","in 10mM DMSO","FDA","USP42-NF37;KP Ⅹ;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","N/A","AChR","Neuronal Signaling","Gallamine Triethiodide  is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM.",891.53,"65-29-2",{"v":100,"d":"100.00"},112.17,{"v":100,"d":"100.00"},112.17,"http://selleckchem.com/products/Gallamine-triethiodide(Flaxedil).html","C30H60I3N3O3","tri-quaternary-N iodide salt","N/A","[I-].[I-].[I-].CC[N+](CC)(CC)CCOC1=C(OCC[N+](CC)(CC)CC)C(=CC=C1)OCC[N+](CC)(CC)CC",-8.065,3,0,21]
["S2473","Hexestrol","c11","L3800-10","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia","N/A","Estrogen/progestogen Receptor","Endocrinology & Hormones","Hexestrol (Bibenzyl) binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.",270.37,"84-16-2",{"v":42,"d":"42.00"},155.34,"<1","N/A","http://selleckchem.com/products/Hexestrol(Bibenzyl).html","C18H22O2","free base","Bibenzyl","CCC(C(CC)C1=CC=C(O)C=C1)C2=CC=C(O)C=C2",5.192,0,2,5]
["S2475","Imatinib (STI571)","d11","L3800-10","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,Bcr-Abl,c-Kit,PDGFR","Protein Tyrosine Kinase","Imatinib (STI571,Gleevec, Glivec, CGP057148B) is a multi-target inhibitor of tyrosine kinase with inhibition for v-Abl, c-Kit and PDGFR, IC50 values are 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib (STI571) induces autophagy.",{"v":493.6,"d":"493.60"},"152459-95-5",{"v":33,"d":"33.00"},66.86,"<1","N/A","http://selleckchem.com/products/Imatinib(STI571).html","C29H31N7O","free base","STI571,Gleevec, Glivec, CGP057148B","CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC=C(C)C(=C3)NC4=NC=CC(=N4)C5=CC=CN=C5",{"v":4.22,"d":"4.220"},4,2,7]
["S2479","Lincomycin HCl","e11","L3800-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Antibiotics for Mammalian Cell Culture,Anti-infection","Microbiology","Lincomycin  hydrochloride (Lincocin, NSC 70731,U10149A) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis.",{"v":443,"d":"443.00"},"859-18-7",{"v":89,"d":"89.00"},{"v":200.9,"d":"200.90"},{"v":89,"d":"89.00"},{"v":200.9,"d":"200.90"},"http://selleckchem.com/products/Lincomycin-hydrochloride(Lincocin).html","C18H34N2O6S.HCl","Hydrochloride","Lincocin, NSC 70731,U10149A","Cl.CCCC1CC(N(C)C1)C(=O)NC(C(C)O)C2OC(SC)C(O)C(O)C2O",0.454,2,5,7]
["S2480","Loperamide HCl","f11","L3800-10","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;EP9.8;BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia","N/A","Autophagy,Opioid Receptor","Neuronal Signaling","Loperamide HCl (ADL 2-1294,R-18553 hydrochloride) is a selective μ-opioid receptor agonist opioid with Ki of 3.3 nM, 15-fold and 350-fold selective over the δ subtype and the κ subtype of the opioid receptor, used against diarrhea resulting from gastroenteritis or inflammatory bowel disease.",{"v":513.5,"d":"513.50"},"34552-83-5",{"v":22,"d":"22.00"},42.84,"<1","N/A","http://selleckchem.com/products/Loperamide-hydrochloride.html","C29H33ClN2O2.HCl","Hydrochloride","ADL 2-1294,R-18553 hydrochloride","Cl.CN(C)C(=O)C(CCN1CCC(O)(CC1)C2=CC=C(Cl)C=C2)(C3=CC=CC=C3)C4=CC=CC=C4",5.017,1,0,7]
["S2481","Manidipine","g11","L3800-10","in 10mM DMSO","CFDA,PMDA,HMA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","Calcium Channel","Transmembrane Transporters","Manidipine(CV-4093,(±)-Manidipine) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive.",{"v":610.7,"d":"610.70"},"89226-50-6",{"v":122,"d":"122.00"},199.77,"<1","N/A","http://selleckchem.com/products/Manidipine(Manyper).html","C35H38N4O6","free base","CV-4093,(±)-Manidipine","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OCCN3CCN(CC3)C(C4=CC=CC=C4)C5=CC=CC=C5)C",5.058,4,1,12]
["S2482","Manidipine 2HCl","h11","L3800-10","in 10mM DMSO","CFDA,PMDA,HMA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","Calcium Channel","Transmembrane Transporters","Manidipine 2HCl (CV-4093) is a HCl salt form of Manidipine, which is a calcium channel blocker with IC50 of 2.6 nM, used clinically as an antihypertensive. Phase 4.",683.62,"89226-75-5",{"v":21,"d":"21.00"},30.72,"<1","N/A","http://selleckchem.com/products/Manidipine-dihydrochloride(CV-4093).html","C35H38N4O6.2HCl","Dihydrochloride","CV-4093","Cl.Cl.COC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OCCN3CCN(CC3)C(C4=CC=CC=C4)C5=CC=CC=C5)C",5.822,4,1,12]
["S2484","Milrinone","a2","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","Phase 2","PDE","Metabolism","Milrinone (Win 47203,Primacor) is a phosphodiesterase 3 (PDE3) inhibitor, used to increase the heart's contractility.",211.22,"78415-72-2",{"v":42,"d":"42.00"},198.84,"<1","N/A","http://selleckchem.com/products/Milrinone(Primacor).html","C12H9N3O","free base","Win 47203,Primacor","CC1=C(C=C(C#N)C(=O)N1)C2=CC=NC=C2",0.356,2,1,1]
["S2485","Mitoxantrone (NSC-301739) 2HCl","b2","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,COVID-19,PKC,Topoisomerase","DNA Damage/DNA Repair","Mitoxantrone 2HCl (NSC-301739) is a dihydrochloride salt of Mitoxantrone. Mitoxantrone is an inhibitor of type II topoisomerase and protein kinase C (PKC) with IC50 of 8.5 μM for PKC. Mitoxantrone inhibits cell proliferative growth of MCF-7/wt cells with IC50 of 0.42 μM. Mitoxantrone also induces apoptosis.",{"v":517.4,"d":"517.40"},"70476-82-3",{"v":89,"d":"89.00"},172.01,{"v":89,"d":"89.00"},172.01,"http://selleckchem.com/products/Mitoxantrone-Hydrochloride.html","C22H29ClN4O6.2HCl","Dihydrochloride","NSC-301739 2HCl","Cl.Cl.OCCNCCNC1=CC=C(NCCNCCO)C2=C1C(=O)C3=C(O)C=CC(=C3C2=O)O",0.832,2,8,12]
["S2486","Moroxydine HCl","c2","L3800-11","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","N/A","Antiviral","Microbiology","Moroxydine HCl(ABOB hydrochloride) is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines.",207.66,"3160-91-6",{"v":42,"d":"42.00"},202.25,{"v":42,"d":"42.00"},202.25,"http://selleckchem.com/products/Moroxydine-hydrochloride.html","C6H13N5O.HCl","Hydrochloride","ABOB hydrochloride","Cl.NC(=N)NC(=N)N1CCOCC1",-0.672,1,2,3]
["S2487","Mycophenolic acid","d2","L3800-11","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37;Martindale:The Extra Pharmacopoeia","N/A","Antineoplastic and Immunosuppressive Antibiotics,Dehydrogenase,Selection Antibiotics for Transfected Cell","Metabolism","Mycophenolic acid (Mycophenolate, RS-61443) is a potent IMPDH inhibitor and the active metabolite of an immunosuppressive drug, used to prevent rejection in organ transplantation.",320.34,"24280-93-1",{"v":64,"d":"64.00"},199.79,"<1","N/A","http://selleckchem.com/products/Mycophenolic-acid(Mycophenolate).html","C17H20O6","free base","Mycophenolate, RS-61443","COC1=C(C)C2=C(C(=C1C\\C=C(/C)CCC(O)=O)O)C(=O)OC2",3.157,4,1,6]
["S2489","Nateglinide","e2","L3800-11","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Potassium Channel","Transmembrane Transporters","Nateglinide (Starlix,A-4166,SDZ DJN 608) is an insulin secretagog agent that lowers blood glucose levels by stimulating insulin secretion from the pancreas.",317.42,"105816-04-4",{"v":63,"d":"63.00"},198.48,"<1","N/A","http://selleckchem.com/products/Nateglinide(Starlix).html","C19H27NO3","free base","Starlix,A-4166,SDZ DJN 608","CC(C)C1CCC(CC1)C(=O)NC(CC2=CC=CC=C2)C(O)=O",3.981,2,1,6]
["S2491","Nitrendipine","f2","L3800-11","in 10mM DMSO","DMF,CFDA,PMDA,HMA","BP2019;EP9.2;KP Ⅹ;JP17;CP2005;Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,Calcium Channel","Transmembrane Transporters","Nitrendipine (Bayotensin) is a dihydropyridine calcium channel blocker with an IC50 of 95 nM.",360.37,"39562-70-4",{"v":72,"d":"72.00"},199.79,"<1","N/A","http://selleckchem.com/products/Nitrendipine.html","C18H20N2O6","free base","Bayotensin","CCOC(=O)C1=C(C)NC(=C(C1C2=CC(=CC=C2)[N+]([O-])=O)C(=O)OC)C",2.115,4,1,7]
["S2492","Novobiocin Sodium (NSC 2382)","g2","L3800-11","in 10mM DMSO","FDA,DMF","USP42-NF37;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Antineoplastic and Immunosuppressive Antibiotics,Topoisomerase","DNA Damage/DNA Repair","Novobiocin Sodium (NSC 2382, Albamycin, Cathomycin) is an aminocoumarin antibiotic that targets bacterial DNA gyrase (TopoIV), used to treat susceptible gram positive bacteria.",634.61,"1476-53-5",{"v":100,"d":"100.00"},157.58,{"v":100,"d":"100.00"},157.58,"http://selleckchem.com/products/Novobiocin-sodium(Albamycin).html","C31H35N2O11.Na","Sodium Salt","Albamycin,Cathomycin,NSC 2382","[Na+].COC1C(OC(N)=O)C(O)C(OC2=CC=C3C(=C(NC(=O)C4=CC=C([O-])C(=C4)CC=C(C)C)C(=O)OC3=C2C)O)OC1(C)C",2.747,8,4,9]
["S2493","Olanzapine","h2","L3800-11","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Phase 2","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Olanzapine (LY170053,Zyprexa, Zalasta, Zolafren, Olzapin, Oferta, Zypadhera) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist.",312.44,"132539-06-1",{"v":62,"d":"62.00"},198.44,"<1","N/A","http://selleckchem.com/products/Olanzapine(Zyprexa).html","C17H20N4S","free base","LY170053,Zyprexa, Zalasta, Zolafren, Olzapin, Oferta, Zypadhera","CN1CCN(CC1)C2=NC3=C(NC4=C2C=C(C)S4)C=CC=C3",{"v":2.69,"d":"2.690"},1,1,1]
["S2494","Olopatadine HCl","a3","L3800-11","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Histamine Receptor","Neuronal Signaling","Olopatadine HCl(ALO4943A,KW4679) is a histamine blocker and mast cell stabilizer with an IC50 of 559 μM for the release of histamine.",373.87,"140462-76-6",{"v":75,"d":"75.00"},{"v":200.6,"d":"200.60"},{"v":13,"d":"13.00"},34.77,"http://selleckchem.com/products/Olopatadine-hydrochloride(Opatanol).html","C21H23NO3.HCl","Hydrochloride","ALO4943A,KW4679","Cl.CN(C)CC\\C=C/1C2=C(COC3=C1C=C(CC(O)=O)C=C3)C=CC=C2",{"v":0.92,"d":"0.920"},2,0,5]
["S2496","Ozagrel","b3","L3800-11","in 10mM DMSO","CFDA,PMDA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","P450 (e.g. CYP17),Prostaglandin Receptor","GPCR & G Protein","Ozagrel (OKY-046) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.",228.25,"82571-53-7",{"v":46,"d":"46.00"},201.53,"<1","N/A","http://selleckchem.com/products/Ozagrel.html","C13H12N2O2","free base","OKY-046","OC(=O)/C=C/C1=CC=C(C[N]2C=CN=C2)C=C1",1.604,2,0,4]
["S2497","Pancuronium dibromide","c3","L3800-11","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Phase 3","AChR","Neuronal Signaling","Pancuronium dibromide(Pavulon) is a competitive nicotinic acetylcholine receptor antagonist, used as a muscle relaxant.",732.67,"15500-66-0",{"v":100,"d":"100.00"},136.49,{"v":100,"d":"100.00"},136.49,"http://selleckchem.com/products/Pancuronium-bromide(Pavulon).html","C35H60N2O4.2Br","di-quaternary-N bromide salt","Pavulon","[Br-].[Br-].CC(=O)OC1CC2CCC3C(CCC4(C)C3CC(C4OC(C)=O)[N+]5(C)CCCCC5)C2(C)CC1[N+]6(C)CCCCC6",-2.043,4,0,6]
["S2499","Phenoxybenzamine HCl","d3","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Phase 4","Adrenergic Receptor","GPCR & G Protein","Phenoxybenzamine HCl (NSC 37448, NCI-c01661) is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.",{"v":340.3,"d":"340.30"},"63-92-3",{"v":68,"d":"68.00"},199.82,{"v":17,"d":"17.00"},49.96,"http://selleckchem.com/products/Phenoxybenzamine-hydrochloride.html","C18H22ClNO.HCl","HCl","NSC 37448, NCI-c01661","Cl.CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2",{"v":4.96,"d":"4.960"},1,0,8]
["S2500","Propafenone HCl","e3","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","N/A","Sodium Channel","Transmembrane Transporters","Propafenone HCl is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias.",{"v":377.9,"d":"377.90"},"34183-22-7",{"v":69,"d":"69.00"},182.59,"<1","N/A","http://selleckchem.com/products/Propafenone(Rytmonorm).html","C21H27NO3.HCl","Hydrochloride","N/A","CCCNCC(O)COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2",3.673,2,2,11]
["S2501","Pyrantel Pamoate","f3","L3800-11","in 10mM DMSO","DMF,CFDA,NDC,PMDA","USP42-NF37;KP Ⅹ;JP17;Ph.Int_5th;IP2010;CP2005","Phase 4","Parasite","Microbiology","Pyrantel pamoate (Pyrantel Embonate), a broad-spectrum anthelmintic drug, is used to treat a number of parasitic worm infections.",594.69,"22204-24-6",{"v":100,"d":"100.00"},168.15,"<1","N/A","http://selleckchem.com/products/Pyrantel-pamoate(Pyrantel-embonate).html","C23H16O6.C11H14N2S","salt","Pyrantel Embonate","CN1CCCN=C1\\C=C\\C2=CC=CS2.OC(=O)C3=CC4=CC=CC=C4C(=C3O)CC5=C6C=CC=CC6=CC(=C5O)C(O)=O",6.203,3,2,6]
["S2502","Quinine HCl Dihydrate","g3","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;EP9.2;Ph.Int_6th ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Potassium Channel","Transmembrane Transporters","Quinine HCl Dihydrate is a white crystalline K+ channel blocker, used to treat malaria.",396.91,"6119-47-7",{"v":79,"d":"79.00"},199.04,{"v":43,"d":"43.00"},108.34,"http://selleckchem.com/products/Quinine-hydrochloride-dihydrate.html","C20H24N2O2.HCl.2H2O","Hydrochloride dihydrate","N/A","O.O.Cl.COC1=CC2=C(C=C1)N=CC=C2C(O)C3CC4CCN3CC4C=C",2.701,2,1,4]
["S2503","Racecadotril","h3","L3800-11","in 10mM DMSO","CFDA,HMA","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Opioid Receptor","Neuronal Signaling","Racecadotril (Acetorphan) is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 μM.",385.48,"81110-73-8",{"v":22,"d":"22.00"},57.07,"<1","N/A","http://selleckchem.com/products/Racecadotril(Acetorphan).html","C21H23NO4S","free base","Acetorphan","CC(=O)SCC(CC1=CC=CC=C1)C(=O)NCC(=O)OCC2=CC=CC=C2",3.128,4,1,11]
["S2504","Ribavirin (ICN-1229)","a4","L3800-11","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;CP2005;Martindale:The Extra Pharmacopoeia","Marketed","Antiviral","Microbiology","Ribavirin (NSC-163039, ICN-1229, RTCA, Tribavirin), a synthetic guanosine analogue, possesses a broad spectrum of activity against DNA and RNA viruses.",244.21,"36791-04-5",{"v":49,"d":"49.00"},200.65,{"v":49,"d":"49.00"},200.65,"http://selleckchem.com/products/Ribavirin(Copegus).html","C8H12N4O5","free base","NSC-163039, RTCA, Tribavirin","NC(=O)C1=N[N](C=N1)C2OC(CO)C(O)C2O",-2.745,4,4,3]
["S2505","Rosiglitazone (BRL-49653) maleate","b4","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,Ferroptosis,PPAR,TRP Channel","Metabolism","Rosiglitazone maleate (BRL-49653C), a member of the thiazolidinedione class of antihyperglycaemic agents, is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-γ (PPAR-γ) with IC50 of 42 nM. Rosiglitazone maleate also modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis.",{"v":473.5,"d":"473.50"},"155141-29-0",{"v":94,"d":"94.00"},198.52,"<1","N/A","http://selleckchem.com/products/Rosiglitazone-maleate.html","C18H19N3O3S.C4H4O4","Maleate","BRL-49653C","CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C3=NC=CC=C3.OC(=O)\\C=C/C(O)=O",3.307,6,1,9]
["S2506","Roxithromycin","c4","L3800-11","in 10mM DMSO","CFDA,PMDA,HMA","BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia;CP2005","Phase 4","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics","Microbiology","Roxithromycin (Roxl-150, Roxo, Surlid, Rulide, Biaxsig, Roxar, Roximycin, Roxomycin, Tirabicin, Coroxin,RU-28965) is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections.",837.07,"80214-83-1",{"v":167,"d":"167.00"},199.51,"<1","N/A","http://selleckchem.com/products/Roxithromycin(Roxl-150).html","C41H76N2O15","free base","Roxl-150, Roxo, Surlid, Rulide, Biaxsig, Roxar, Roximycin, Roxomycin, Tirabicin, Coroxin,RU-28965","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)C(=N/OCOCCOC)/C(C)C(O)C1(C)O",1.619,11,3,13]
["S2508","Scopolamine (LSM-4015) HBr","d4","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;KP Ⅹ;EP9.2;JP17;IP2010;CP2005","Phase 2/3","AChR","Neuronal Signaling","Scopolamine HBr (LSM-4015,NSC 61806,(-)-Scopolamine hydrobromide, Hyoscine hydrobromide, Scopine hydrobromide) is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55.3 nM.",384.26,"114-49-8",{"v":76,"d":"76.00"},197.78,{"v":76,"d":"76.00"},197.78,"http://selleckchem.com/products/Scopolamine-hydrobromide.html","C17H21NO4.HBr","Hydrobromide","LSM-4015,NSC 61806,(-)-Scopolamine hydrobromide, Hyoscine hydrobromide, Scopine hydrobromide","Br.CN1C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4",1.314,3,1,5]
["S2509","Sotalol HCl","e4","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Sotalol(MJ-1999)  is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 μM.",308.82,"959-24-0",{"v":61,"d":"61.00"},197.53,{"v":61,"d":"61.00"},197.53,"http://selleckchem.com/products/Sotalol-hydrochloride(Betapace).html","C12H20N2O3S.HCl","Hydrochloride","MJ-1999","Cl.CC(C)NCC(O)C1=CC=C(N[S](C)(=O)=O)C=C1",0.876,2,3,6]
["S2510","Spectinomycin 2HCl","f4","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","N/A","Antibiotics,Antibiotics for Mammalian Cell Culture,Selection Antibiotics for Transfected Cell","Microbiology","Spectinomycin 2HCl (Actinospectacin) is a new parenteral antibiotic prepared from Streptomyces spectabilis.",405.27,"21736-83-4",{"v":81,"d":"81.00"},199.87,{"v":81,"d":"81.00"},199.87,"http://selleckchem.com/products/Spectinomycin-hydrochloride.html","C14H24N2O7.2HCl","dihydrochloride","Actinospectacin","Cl.Cl.CNC1C(O)C(NC)C2OC3(O)C(OC(C)CC3=O)OC2C1O",-1.566,4,4,2]
["S2511","Sulfadoxine","g4","L3800-11","in 10mM DMSO","FDA,DMF,CFDA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;Martindale:The Extra Pharmacopoeia","Phase 2","Anti-infection","Microbiology","Sulfadoxine (Sulphadoxine) is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax.",310.33,"2447-57-6",{"v":62,"d":"62.00"},199.78,"<1","N/A","http://selleckchem.com/products/Sulfadoxine(Sulphadoxine).html","C12H14N4O4S","free base","Sulphadoxine","COC1=C(OC)C(=NC=N1)N[S](=O)(=O)C2=CC=C(N)C=C2",0.837,6,2,5]
["S2512","Tenoxicam","h4","L3800-11","in 10mM DMSO","marketed in Japan","EP9.4;BP2019;KP Ⅹ;Martindale:The Extra Pharmacopoeia","Phase 4","Immunology & Inflammation related","Immunology & Inflammation","Tenoxicam(Ro-12-0068) is a good HO. radicals scavenger with an IC50 of 56.7 μM.",337.38,"59804-37-4",{"v":68,"d":"68.00"},201.55,"<1","N/A","http://selleckchem.com/products/Tenoxicam(Mobiflex).html","C13H11N3O4S2","free base","Ro-12-0068","CN1C(=C(O)C2=C(C=CS2)[S]1(=O)=O)C(=O)NC3=CC=CC=N3",0.454,4,2,2]
["S2515","Vardenafil HCl Trihydrate","a5","L3800-11","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","PDE","Metabolism","Vardenafil HCl Trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.",579.11,"330808-88-3",{"v":100,"d":"100.00"},172.68,{"v":10,"d":"10.00"},17.27,"http://selleckchem.com/products/Vardenafil(Vivanza).html","C23H32N6O4S.HCl.3H2O","Hydrochloride trihydrate","BAY38-9456","O.O.O.Cl.CCCC1=NC(=C2[N]1N=C(NC2=O)C3=CC(=CC=C3OCC)[S](=O)(=O)N4CCN(CC)CC4)C",2.109,6,1,8]
["S2516","Xylazine HCl","b5","L3800-11","in 10mM DMSO","DMF","USP42-NF37;EP9.8;BP2019;Martindale:The Extra Pharmacopoeia","N/A","Adrenergic Receptor","Neuronal Signaling","Xylazine(BAY 1470 hydrochloride) is an α2-Adrenergic receptor agonist, used as a sedative and muscle relaxant.",256.79,"23076-35-9",{"v":50,"d":"50.00"},194.71,{"v":12,"d":"12.00"},46.73,"http://selleckchem.com/products/Xylazine(Rompun).html","C12H16N2S.HCl","Hydrochloride","BAY 1470 hydrochloride","Cl.CC1=C(NC2=NCCCS2)C(=CC=C1)C",3.647,1,1,2]
["S2517","Maprotiline HCl","c5","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","N/A","Adrenergic Receptor","Neuronal Signaling","Maprotiline HCl is a selective noradrenalin re-uptake inhibitor, used in the treatment of depression.",313.86,"10347-81-6",{"v":63,"d":"63.00"},200.73,"<1","N/A","http://selleckchem.com/products/Maprotiline-hydrochloride.html","C20H23N.HCl","Hydrochloride","N/A","Cl.CNCCCC12CCC(C3=CC=CC=C13)C4=C2C=CC=C4",4.498,0,1,4]
["S2519","Naphazoline HCl","d5","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;IP2010;CP2005;Martindale:The Extra Pharmacopoeia","N/A","Adrenergic Receptor","Neuronal Signaling","Naphazoline HCl is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.",246.74,"550-99-2",{"v":17,"d":"17.00"},{"v":68.9,"d":"68.90"},{"v":49,"d":"49.00"},198.59,"http://selleckchem.com/products/Naphazoline-hydrochloride-Naphcon.html","C14H14N2.HCl","Hydrochloride","N/A","Cl.C1CN=C(CC2=C3C=CC=CC3=CC=C2)N1",2.442,1,1,2]
["S2521","Epinephrine bitartrate","e5","L3800-11","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37;IP2010","Registered","Adrenergic Receptor","GPCR & G Protein","Epinephrine bitartrate (Adrenalinium) is an alpha- and beta-adrenergic receptor stimulator.",333.29,"51-42-3",{"v":67,"d":"67.00"},201.03,{"v":67,"d":"67.00"},201.03,"http://selleckchem.com/products/Epinephrine-bitartrate-Adrenalinium.html","C9H13NO3.C4H6O6","tartrate","Adrenalinium","CNCC(O)C1=CC(=C(O)C=C1)O.OC(C(O)C(O)=O)C(O)=O",-3.996,2,6,6]
["S2524","Phenytoin Sodium","f5","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","BP2019;EP9.6;KP Ⅹ ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 2","Sodium Channel","Transmembrane Transporters","Phenytoin Sodium (Aleviatin, Diphenylhydantoin sodium, Eptoin, Phenytoin soluble, Prompt; Phenytek,Dilantin sodium, Diphantoine) is an inactive voltage-gated sodium channel stabilizer.",274.25,"630-93-3",{"v":32,"d":"32.00"},116.68,{"v":3,"d":"3.00"},10.94,"http://selleckchem.com/products/Phenytoin-sodium-Dilantin.html","C15H11N2NaO2","Sodium Salt","Aleviatin, Diphenylhydantoin sodium, Eptoin, Phenytoin soluble, Prompt,Phenytek,Dilantin sodium, Diphantoine","[Na+].[O-]C1=NC(=O)C(N1)(C2=CC=CC=C2)C3=CC=CC=C3",2.084,2,1,2]
["S2525","Phenytoin","g5","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","BP2019;EP9.6;KP Ⅹ ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 4","Sodium Channel","Transmembrane Transporters","Phenytoin (Di-Hydan, Dihycon, Dilabid, Diphedan, Diphenat, Diphenylan, Diphenylhydantoin, Hydantol, Lehydan, NSC 8722) is an inactive voltage-gated sodium channel stabilizer.",252.27,"57-41-0",{"v":50,"d":"50.00"},{"v":198.2,"d":"198.20"},"<1","N/A","http://selleckchem.com/products/Phenytoin-Lepitoin.html","C15H12N2O2","Free Base","Di-Hydan, Dihycon, Dilabid, Diphedan, Diphenat, Diphenylan, Diphenylhydantoin, Hydantol, Lehydan, NSC 8722","O=C1NC(=O)C(N1)(C2=CC=CC=C2)C3=CC=CC=C3",2.105,2,2,2]
["S2528","Ciclopirox","h5","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","ATPase,Fungal","Transmembrane Transporters","Ciclopirox(HOE 296b, Penlac) is a broad-spectrum antifungal agent working as an iron chelator.",207.27,"29342-05-0",{"v":42,"d":"42.00"},202.63,"<1","N/A","http://selleckchem.com/products/Ciclopirox-Penlac.html","C12H17NO2","Free Base","HOE 296b, Penlac","CC1=CC(=O)N(O)C(=C1)C2CCCCC2",2.489,1,0,1]
["S2529","Dopamine HCl","a6","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Ph.Int_6th;Martindale:The Extra Pharmacopoeia","N/A","Dopamine Receptor","Neuronal Signaling","Dopamine HCl(ASL279, NSC 173182) is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.",189.64,"62-31-7",{"v":38,"d":"38.00"},200.38,{"v":38,"d":"38.00"},200.38,"http://selleckchem.com/products/Dopamine-hydrochloride-Inotropin.html","C8H11NO2.HCl","Hydrochloride","ASL279, NSC 173182","Cl.NCCC1=CC(=C(O)C=C1)O",1.155,0,3,2]
["S2532","L-Ascorbyl 6-palmitate","b6","L3800-11","in 10mM DMSO","N/A","USP42-NF37","Marketed","N/A","Others","Ascorbyl palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C.",414.53,"137-66-6",{"v":83,"d":"83.00"},200.23,"<1","N/A","http://selleckchem.com/products/L-Ascorbyl-6-palmitate.html","C22H38O7","free base","N/A","CCCCCCCCCCCCCCCC(=O)OCC(O)C1OC(=O)C(=C1O)O",5.268,4,3,18]
["S2533","Ritodrine HCl","c6","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,PMDA","USP42-NF37;BP2019;JP17;Martindale:The Extra Pharmacopoeia","Phase 4","Adrenergic Receptor","Neuronal Signaling","Ritodrine HCl (NSC 291565,DU 21220, Ritodrine) is a hydrochloride salt of ritodrine which is a β-2 adrenergic receptor agonist.",323.81,"23239-51-2",{"v":65,"d":"65.00"},200.73,{"v":65,"d":"65.00"},200.73,"http://selleckchem.com/products/Ritodrine-hydrochloride-Yutopar.html","C17H21NO3.HCl","Hydrochloride","NSC 291565,DU 21220, Ritodrine","Cl.CC(NCCC1=CC=C(O)C=C1)C(O)C2=CC=C(O)C=C2",3.037,0,4,6]
["S2534","Isoconazole nitrate","d6","L3800-11","in 10mM DMSO","PMDA","BP2019;EP9.2;KP Ⅹ;Martindale:The Extra Pharmacopoeia","N/A","Fungal","Microbiology","Isoconazole nitrate (Travogen,Adestan G 100, R 15454) is an azole antifungal reagent.",479.14,"24168-96-5",{"v":41,"d":"41.00"},85.57,"<1","N/A","http://selleckchem.com/products/Isoconazole-nitrate-Travogen.html","C18H14Cl4N2O.HNO3","Nitrate","Travogen,Adestan G 100, R 15454","O[N+]([O-])=O.ClC1=CC=C(C(C[N]2C=CN=C2)OCC3=C(Cl)C=CC=C3Cl)C(=C1)Cl",4.387,2,0,6]
["S2535","Econazole nitrate","e6","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia;CP2005","Marketed","Calcium Channel,Fungal","Transmembrane Transporters","Econazole Nitrate (NSC 243115,Spectazole) is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus.",{"v":444.7,"d":"444.70"},"24169-02-6",{"v":89,"d":"89.00"},200.13,"<1","N/A","http://selleckchem.com/products/Econazole-nitrate-Spectazole.html","C18H15Cl3N2O.HNO3","Nitrate","NSC 243115,Spectazole","O[N+]([O-])=O.ClC1=CC=C(COC(C[N]2C=CN=C2)C3=CC=C(Cl)C=C3Cl)C=C1",3.722,2,0,6]
["S2536","Miconazole","f6","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.7;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Fungal","Microbiology","Miconazole (Monistat,R18134) is an imidazole antifungal agent.",416.13,"22916-47-8",{"v":83,"d":"83.00"},199.46,"<1","N/A","http://selleckchem.com/products/Miconazole-Monistat.html","C18H14Cl4N2O","Free Base","Monistat,R18134","ClC1=CC=C(COC(C[N]2C=CN=C2)C3=C(Cl)C=C(Cl)C=C3)C(=C1)Cl",5.645,2,0,6]
["S2537","Secnidazole","g6","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC","IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Anti-infection","Microbiology","Secnidazole (Flagentyl, PM 185184, RP 14539) is a nitroimidazole anti-infective.",185.18,"3366-95-8",{"v":37,"d":"37.00"},199.81,{"v":37,"d":"37.00"},199.81,"http://selleckchem.com/products/Secnidazole-Flagentyl.html","C7H11N3O3","free base","PM 185184, RP 14539","CC(O)C[N]1C(=NC=C1[N+]([O-])=O)C",{"v":0.04,"d":"0.040"},1,1,3]
["S2541","Clomipramine HCl","h6","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Serotonin Transporter","Neuronal Signaling","Clomipramine HCl(Anafranil) is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively.",351.31,"17321-77-6",{"v":70,"d":"70.00"},199.25,{"v":70,"d":"70.00"},199.25,"http://selleckchem.com/products/Clomipramine-hydrochloride-Anafranil.html","C19H23ClN2.HCl","Hydrochloride","Anafranil","Cl.CN(C)CCCN1C2=C(CCC3=C1C=C(Cl)C=C3)C=CC=C2",5.434,0,0,4]
["S2543","Ceftiofur HCl","a7","L3800-11","in 10mM DMSO","N/A","USP42-NF37;Martindale:The Extra Pharmacopoeia","N/A","Antibiotics,Bacterial","Microbiology","Ceftiofur HCl (U-67279A,Excenel hydrochloride) is a cephalosporin antibiotic, used to treat both Gram-positive and Gram-negative bacteria infection.",560.02,"103980-44-5",{"v":100,"d":"100.00"},178.57,"<1","N/A","http://selleckchem.com/products/Ceftiofur-hydrochloride.html","C19H17N5O7S3.HCl","Hydrochloride","U-67279A,Excenel hydrochloride","Cl.CO/N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)CSC(=O)C3=CC=CO3)C4=CSC(=N4)N",{"v":1.09,"d":"1.090"},8,2,9]
["S2547","Tiotropium Bromide hydrate","b7","L3800-11","in 10mM DMSO","PMDA","BP2019;EP9.3;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","AChR","Neuronal Signaling","Tiotropium Bromide hydrate (BA 679BR) is a monohydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a muscarinic receptor antagonist.",490.43,"139404-48-1",{"v":8,"d":"8.00"},16.31,"<1","N/A","http://selleckchem.com/products/Tiotropium-Bromide-hydrate.html","C19H22NO4S2.Br.xH2O","quaternary-N bromide salt&hydr","BA 679BR","O.[Br-].C[N+]1(C)C2CC(CC1C3OC23)OC(=O)C(O)(C4=CC=CS4)C5=CC=CS5",-1.727,3,0,5]
["S2549","Trospium chloride","c7","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Marketed","AChR","Neuronal Signaling","Trospium chloride  is a competitive muscarinic cholinergic receptor antagonist.",427.96,"10405-02-4",{"v":41,"d":"41.00"},{"v":95.8,"d":"95.80"},{"v":86,"d":"86.00"},200.95,"http://selleckchem.com/products/Trospium-chloride-Sanctura.html","C25H30NO3.Cl","quaternary-N chloride salt","N/A","[Cl-].OC(C(=O)OC1CC2CCC(C1)[N+]23CCCC3)(C4=CC=CC=C4)C5=CC=CC=C5",-0.324,2,0,5]
["S2551","Sulbactam sodium","d7","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","BP2019;EP9.2;KP Ⅹ;JP17;CP2005;Martindale:The Extra Pharmacopoeia","Marketed","β-lactamase","Microbiology","Sulbactam sodium (Unasyn, CP-45899-2) is an irreversible β-lactamase inhibitor.",255.22,"69388-84-7",{"v":3,"d":"3.00"},11.75,{"v":51,"d":"51.00"},199.83,"http://selleckchem.com/products/sulbactam-sodium-unasyn.html","C8H10NO5S.Na","Sodium  salt","Unasyn, CP-45899-2","[Na+].CC1(C)C(N2C(CC2=O)[S]1(=O)=O)C([O-])=O",-2.145,3,0,1]
["S2552","Azelastine HCl","e7","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Histamine Receptor","Neuronal Signaling","Azelastine HCl is a potent, second-generation, selective, histamine receptor antagonist, used in the treatment of rhinitis.",418.36,"79307-93-0",{"v":28,"d":"28.00"},66.93,{"v":35,"d":"35.00"},83.66,"http://selleckchem.com/products/azelastine.html","C22H24ClN3O.HCl","Hydrochloride","N/A","Cl.CN1CCCC(CC1)N2N=C(CC3=CC=C(Cl)C=C3)C4=CC=CC=C4C2=O",4.476,2,0,3]
["S2553","5-Aminolevulinic acid HCl","f7","L3800-11","in 10mM DMSO","DMF,EMA","Martindale:The Extra Pharmacopoeia","Marketed","Others","Others","5-Aminolevulinic Acid HCl(5-ALA hydrochloride) is an intermediate in the porphyrin synthesis pathway, used as a photosensitizing agent and a antineoplastic agent.",167.59,"5451-09-2",{"v":34,"d":"34.00"},202.88,{"v":34,"d":"34.00"},202.88,"http://selleckchem.com/products/5-Aminolevulinic-acid-hydrochloride.html","C5H9NO3.HCl","Hydrochloride","5-ALA hydrochloride","Cl.NCC(=O)CCC(O)=O",-3.318,2,1,4]
["S2554","Daphnetin","g7","L3800-11","in 10mM DMSO","CFDA","N/A","N/A","EGFR,PKA,PKC","Angiogenesis","Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor, inhibits EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively, also known to exhibit anti-inflammatory and anti-oxidant activities.",178.14,"486-35-1",{"v":35,"d":"35.00"},196.47,"<1","N/A","http://selleckchem.com/products/Daphnetin.html","C9H6O4","free base","N/A","OC1=CC=C2C=CC(=O)OC2=C1O",1.415,2,2,0]
["S2555","Clarithromycin","h7","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.4;KP Ⅹ;JP17;IP2010;CP2005;Martindale:The Extra Pharmacopoeia","Marketed","P450 (e.g. CYP17)","Metabolism","Clarithromycin (A-56268) is a macrolide antibiotic and a CYP3A4 inhibitor, used to treat a number of bacterial infections.",747.95,"81103-11-9",{"v":25,"d":"25.00"},33.42,"<1","N/A","http://selleckchem.com/products/clarithromycin.html","C38H69NO13","free base","A-56268","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(CC(C)C(=O)C(C)C(O)C1(C)O)OC",{"v":2.2,"d":"2.200"},9,3,8]
["S2556","Rosiglitazone (BRL 49653)","a8","L3800-11","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","USP42-NF37;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,Ferroptosis,PPAR,TRP Channel","Metabolism","Rosiglitazone (BRL 49653) is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively. Rosiglitazone is a pure ligand of PPAR-gamma, and has no PPAR-alpha-binding action. Rosiglitazone modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis.",357.43,"122320-73-4",{"v":71,"d":"71.00"},198.64,"<1","N/A","http://selleckchem.com/products/Rosiglitazone-Avandia.html","C18H19N3O3S","Free Base","BRL 49653","CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C3=CC=CC=N3",3.268,4,1,7]
["S2557","Terbinafine HCl","b8","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Fungal","Microbiology","Terbinafine HCl (KWD 201,KWD 2019,TDT 067 hydrochloride) inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug.",327.89,"78628-80-5",{"v":66,"d":"66.00"},201.29,"<1","N/A","http://selleckchem.com/products/Terbinafine-hydrochloride-Lamisil.html","C21H25N.HCl","Hydrochloride","KWD 201,KWD 2019,TDT 067 hydrochloride","Cl.CN(C\\C=C\\C#CC(C)(C)C)CC1=CC=CC2=C1C=CC=C2",5.717,0,0,6]
["S2559","Cortisone acetate","c8","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","BP2015;USP38-NF33;BP2013 ;IP2010;CP2005;Martindale:The Extra Pharmacopoeia","Phase 2/3","Glucocorticoid Receptor","Endocrinology & Hormones","Cortisone acetate (Cortone, NSC 49420) is an acetate salt form of cortisone that is a steroid hormone and a glucocorticoid.",402.48,"50-04-4",{"v":7,"d":"7.00"},17.39,"<1","N/A","http://selleckchem.com/products/Cortisone-acetate-Cortone.html","C23H30O6","free base","Cortone,NSC 49420","CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3C(=O)CC12C",1.619,5,0,4]
["S2561","Clomifene citrate","d8","L3800-11","in 10mM DMSO","CFDA,PMDA","BP2019 ;EP9.5;KP Ⅹ ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Estrogen/progestogen Receptor","Endocrinology & Hormones","Clomifene citrate (NSC 35770, Clomiphene citrate) is a selective estrogen receptor modulator, used in the treatment of ovulation induction.",598.08,"50-41-9",{"v":120,"d":"120.00"},200.64,"<1","N/A","http://selleckchem.com/products/Clomifene-citrate-Serophene.html","C26H28ClNO.C6H8O7","Citrate","NSC 35770, Clomiphene citrate","CCN(CC)CCOC1=CC=C(C=C1)C(=C(Cl)/C2=CC=CC=C2)/C3=CC=CC=C3.OC(=O)CC(O)(CC(O)=O)C(O)=O",2.129,4,0,14]
["S2564","Cloxacillin Sodium","e8","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,HMA","BP2019 ;EP9.2;KP Ⅹ ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Anti-infection","Microbiology","Cloxacillin Sodium(Cloxacap,BRL 1621 sodium salt) is a sodium salt of cloxacillin that is a penicillinase-resistant, acid resistant, semi-synthetic penicillin.",475.88,"7081-44-9",{"v":55,"d":"55.00"},115.58,{"v":55,"d":"55.00"},115.58,"http://selleckchem.com/products/Cloxacillin-sodium-Cloxacap.html","C19H19ClN3NaO6S","Sodium Salt & hydrate","Cloxacap,BRL 1621 sodium salt","O.[Na+].CC1=C(C(=O)NC2C3SC(C)(C)C(N3C2=O)C([O-])=O)C(=NO1)C4=CC=CC=C4Cl",0.619,4,1,4]
["S2565","Amoxicillin Sodium","f8","L3800-11","in 10mM DMSO","DMF,CFDA,HMA","BP2019;EP9.2;KP Ⅹ;IP2010;CP2005;Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics,Bacterial","Microbiology","Amoxicillin Sodium (Clavulanate,Amoxycillin sodium) is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.",387.39,"34642-77-8",{"v":78,"d":"78.00"},201.35,{"v":78,"d":"78.00"},201.35,"http://selleckchem.com/products/amoxicillin-amox.html","C16H18N3O5S.Na","Sodium Salt","Clavulanate,Amoxycillin sodium","[Na+].CC1(C)SC2C(NC(=O)C(N)C3=CC=C(O)C=C3)C(=O)N2C1C([O-])=O",-1.534,2,3,4]
["S2566","Isoprenaline (NCI-C55630) HCl","g8","L3800-11","in 10mM DMSO","DMF,CFDA","BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Phase 2","Adrenergic Receptor","Neuronal Signaling","Isoprenaline HCl (NCI-c55630,Isoproterenol hydrochloride) is a non-selective beta-adrenergic receptor agonist, used for the treatment of bradycardia and heart block.",247.72,"51-30-9",{"v":50,"d":"50.00"},201.84,{"v":50,"d":"50.00"},201.84,"http://selleckchem.com/products/Isoprenaline-hydrochloride.html","C11H17NO3.HCl","Hydrochloride","NCI-c55630,Isoproterenol hydrochloride","Cl.CC(C)NCC(O)C1=CC=C(O)C(=C1)O",1.481,0,4,4]
["S2567","Medroxyprogesterone acetate (NSC-26386)","h8","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Medroxyprogesterone acetate (MPA, NSC-26386, Medroxyprogesterone 17-acetate, Farlutin) is a synthetic progestin and act as a potent progesterone receptor agonist, used to treat abnormal menstruation or irregular vaginal bleeding.",386.52,"71-58-9",{"v":12,"d":"12.00"},31.05,"<1","N/A","http://selleckchem.com/products/Medroxyprogesterone-acetate.html","C24H34O4","Free Base","MPA, NSC-26386, Medroxyprogesterone 17-acetate, Farlutin","CC1CC2C(CCC3(C)C2CCC3(OC(C)=O)C(C)=O)C4(C)CCC(=O)C=C14",3.755,4,0,3]
["S2569","Phenylephrine (NCI-C55641) HCl","a9","L3800-11","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","GPCR & G Protein","Phenylephrine HCl (NCI-c55641,Phenylephrine hydrochloride,(R)-(-)-Phenylephrine hydrochloride, L-Phenylephrine hydrochloride) is a selective α1-adrenergic receptor agonist, used primarily as a decongestant.",203.67,"61-76-7",{"v":41,"d":"41.00"},201.31,{"v":41,"d":"41.00"},201.31,"http://selleckchem.com/products/Phenylephrine-hydrochloride.html","C9H13NO2.HCl","Hydrochloride","NCI-c55641,Phenylephrine hydrochloride,(R)-(-)-Phenylephrine hydrochloride, L-Phenylephrine hydrochloride","Cl.CNCC(O)C1=CC(=CC=C1)O",0.997,0,3,3]
["S2570","Prednisolone Acetate","b9","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37 ;KP Ⅹ;EP9.2;Ph.Int_6th;JP17;BP2016;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","Glucocorticoid Receptor","Endocrinology & Hormones","Prednisolone Acetate (Omnipred,Prednisolone-21-acetate) is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant agent.",402.48,"52-21-1",{"v":81,"d":"81.00"},201.25,"<1","N/A","http://selleckchem.com/products/Prednisolone-acetate-Omnipred.html","C23H30O6","free base","Omnipred,Prednisolone-21-acetate","CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)C=CC4(C)C3C(O)CC12C",1.639,4,1,4]
["S2573","Tetracaine HCl","c9","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Calcium Channel","Transmembrane Transporters","Tetracaine HCl (Amethocaine hydrochloride) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.",300.82,"136-47-0",{"v":60,"d":"60.00"},199.45,{"v":60,"d":"60.00"},199.45,"http://selleckchem.com/products/tetracaine-hydrochloride-pontocaine.html","C15H24N2O2.HCl","Hydrochloride","Amethocaine hydrochloride","Cl.CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C",3.343,2,1,9]
["S2574","Tetracycline HCl","d9","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","BP2013;IP2010 ;Martindale:The Extra Pharmacopoeia","Phase 2","Antibiotics,Antibiotics for Mammalian Cell Culture,Selection Antibiotics for Transfected Cell","Microbiology","Tetracycline HCl (NCI-c55561) is a hydrochloride salt of tetracycline that is a broad-spectrum polyketide antibiotic.",{"v":480.9,"d":"480.90"},"64-75-5",{"v":96,"d":"96.00"},199.63,{"v":96,"d":"96.00"},199.63,"http://selleckchem.com/products/tetracycline-hydrochloride.html","C22H24N2O8.HCl","Hydrochloride","NCI-c55561","Cl.CN(C)C1C2CC3C(=C(O)C2(O)C(=O)C(=C1O)C(N)=O)C(=O)C4=C(O)C=CC=C4C3(C)O",-0.513,3,4,2]
["S2576","Xylometazoline HCl","e9","L3800-11","in 10mM DMSO","DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;IP2010;Martindale:The Extra Pharmacopoeia","Phase 3","Adrenergic Receptor","GPCR & G Protein","Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM.",280.84,"1218-35-5",{"v":27,"d":"27.00"},96.14,{"v":56,"d":"56.00"},{"v":199.4,"d":"199.40"},"http://selleckchem.com/products/xylometazoline-hcl.html","C16H24N2.HCl","HCl","N/A","Cl.CC1=C(CC2=NCCN2)C(=CC(=C1)C(C)(C)C)C",3.906,1,1,3]
["S2577","Phenacetin","f9","L3800-11","in 10mM DMSO","DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;IP2010;Martindale:The Extra Pharmacopoeia","N/A","COX","Neuronal Signaling","Phenacetin (Acetophenetidin) is a non-opioid analgesic without anti-inflammatory properties.",179.22,"62-44-2",{"v":36,"d":"36.00"},200.87,"<1","N/A","http://selleckchem.com/products/phenacetin.html","C10H13NO2","free base","Acetophenetidin","CCOC1=CC=C(NC(C)=O)C=C1",1.282,2,1,3]
["S2579","Zidovudine","g9","L3800-11","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","CRISPR/Cas9,Reverse Transcriptase","Microbiology","Zidovudine (ZDV, Azidothymidine, NSC 602670,Retrovir) is a nucleoside analogue reverse transcriptase inhibitor, used to treat HIV. It could decrease the HDR efficiency and decrease CRISPR-mediated sequence-specific genome knockin events while increaseing knockout efficiency.",267.24,"30516-87-1",{"v":53,"d":"53.00"},198.32,{"v":53,"d":"53.00"},198.32,"http://selleckchem.com/products/zidovudine-retrovir.html","C10H13N5O4","free base","Azidothymidine, NSC 602670,Retrovir","CC1=CN(C2CC(N=[N+]=[N-])C(CO)O2)C(=O)NC1=O",0.064,4,2,3]
["S2581","Quinapril HCl","h9","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","Marketed","RAAS","Endocrinology & Hormones","Quinapril HCl (CI-906, PD-109452-2) is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM.",474.98,"82586-55-8",{"v":18,"d":"18.00"},{"v":37.9,"d":"37.90"},{"v":95,"d":"95.00"},200.01,"http://selleckchem.com/products/quinapril-hydrochloride-accupril.html","C25H30N2O5.HCl","Hydrochloride","CI-906, PD-109452-2","Cl.CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=C(CC2C(O)=O)C=CC=C3",1.038,4,1,10]
["S2583","Thiamphenicol","a10","L3800-11","in 10mM DMSO","DMF,CFDA","BP2019;EP9.2;KP Ⅹ;Martindale:The Extra Pharmacopoeia","N/A","Antibiotics","Microbiology","Thiamphenicol (Thiophenicol,Dextrosulphenidol) is an antimicrobial antibiotic and a methyl-sulfonyl analogue of chloramphenicol.",356.22,"15318-45-3",{"v":71,"d":"71.00"},199.32,"<1","N/A","http://selleckchem.com/products/thiamphenicol-thiophenicol.html","C12H15Cl2NO5S","free base","Thiophenicol,Dextrosulphenidol","C[S](=O)(=O)C1=CC=C(C=C1)C(O)C(CO)NC(=O)C(Cl)Cl",0.657,3,3,6]
["S2584","Clobetasol propionate","b10","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Glucocorticoid Receptor","Endocrinology & Hormones","Clobetasol propionate (CGP9555, CCl 4725) is an anti-inflammatory corticosteroid used to treat various skin disorders.",466.97,"25122-46-7",{"v":93,"d":"93.00"},199.16,"<1","N/A","http://selleckchem.com/products/clobetasol-propionate.html","C25H32ClFO5","free base","CGP9555, CCl 4725","CCC(=O)OC1(C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)CCl",3.958,4,1,5]
["S2585","Brompheniramine hydrogen maleate","c10","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","Phase 3","Histamine Receptor","Neuronal Signaling","Brompheniramine hydrogen maleate(Brompheniramine maleate) is a histamine H1 receptors antagonist.",435.31,"980-71-2",{"v":87,"d":"87.00"},199.86,{"v":46,"d":"46.00"},105.67,"http://selleckchem.com/products/brompheniramine.html","C16H19BrN2.C4H4","Maleate","Brompheniramine maleate","CN(C)CCC(C1=CC=C(Br)C=C1)C2=CC=CC=N2.OC(=O)\\C=C/C(O)=O",0.784,3,0,7]
["S2586","Dimethyl Fumarate","d10","L3800-11","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Nrf2","Immunology & Inflammation","Dimethyl fumarate (DMF,Tecfidera,BG-12) is the methyl ester of fumaric acid, used to treat people with relapsing forms of multiple sclerosis. Dimethyl fumarate is a nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator and induces upregulation of antioxidant gene expression.",144.13,"624-49-7",{"v":29,"d":"29.00"},201.21,"<1","N/A","http://selleckchem.com/products/dimethyl-Fumarate.html","C6H8O4","free base","DMF,Tecfidera,BG-12","COC(=O)\\C=C\\C(=O)OC",{"v":0.49,"d":"0.490"},4,0,4]
["S2589","Miglitol","e10","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","JP17;Martindale:The Extra Pharmacopoeia","Marketed","Carbohydrate Metabolism","Metabolism","Miglitol (BAY-M-1099,Glyset) is an oral anti-diabetic drug.",207.22,"72432-03-2",{"v":3,"d":"3.00"},14.48,"<1","N/A","http://selleckchem.com/products/miglitol-glyset.html","C8H17NO5","free base","BAY-M-1099,Glyset","OCCN1CC(O)C(O)C(O)C1CO",-2.444,0,5,3]
["S2590","Pioglitazone (AD-4833)","f10","L3800-11","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","PPAR","Metabolism","Pioglitazone (AD-4833, U 72107) is a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, used to treat diabetes; A weak activator for full-length hPPARα, but not full-length hPPARδ.",356.44,"111025-46-8",{"v":10,"d":"10.00"},28.06,"<1","N/A","https://www.selleckchem.com/products/pioglitazone.html","C19H20N2O3S","Free Base","U 72107","CCC1=CC=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)N=C1",3.907,4,1,7]
["S2593","Tolvaptan","g10","L3800-11","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Vasopressin Receptor","GPCR & G Protein","Tolvaptan (OPC-41061) is an orally effective nonpeptide arginine vasopressin V2 receptor antagonist with IC50 of 3 nM, used to treat hyponatremia.",448.94,"150683-30-0",{"v":89,"d":"89.00"},198.24,"<1","N/A","http://selleckchem.com/products/tolvaptan-opc-41061.html","C26H25ClN2O3","free base","OPC-41061","CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(O)C4=C3C=CC(=C4)Cl)C",5.127,2,2,3]
["S2594","Pramiracetam","h10","L3800-11","in 10mM DMSO","marketed in Italy","Martindale:The Extra Pharmacopoeia","Marketed","Others","Others","Pramiracetam (CI-879,Pramistar) is a more potent nootropic drug derived from piracetam.",269.38,"68497-62-1",{"v":54,"d":"54.00"},200.46,"<1","N/A","http://selleckchem.com/products/pramiracetam.html","C14H27N3O2","free base","CI-879,Pramistar","CC(C)N(CCNC(=O)CN1CCCC1=O)C(C)C",0.486,2,1,7]
["S2596","Clindamycin palmitate HCl","a11","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37;EP9.3;BP2019;KP Ⅹ;JP17;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Marketed","Bacterial","Microbiology","Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic.",699.85,"25507-04-4",{"v":140,"d":"140.00"},200.04,{"v":140,"d":"140.00"},200.04,"http://selleckchem.com/products/clindamycin-palmitate-hcl.html","C34H63ClN2O6S.HCl","Hydrochloride","N/A","Cl.CCCCCCCCCCCCCCCC(=O)OC1C(O)C(O)C(OC1SC)C(NC(=O)C2CC(CCC)CN2C)C(C)Cl",8.635,4,3,23]
["S2599","L-Thyroxine","b11","L3800-11","in 10mM DMSO","N/A","USP42-NF37;IP2010","Marketed","THR","Metabolism","L-Thyroxine (NSC 36397,Levothyroxine) is a synthetic form of thyroxine and a hormone replacement drug.",776.87,"51-48-9",{"v":100,"d":"100.00"},128.72,"<1","N/A","http://selleckchem.com/products/l-thyroxine.html","C15H11I4NO4","free base","NSC 36397,Levothyroxine","NC(CC1=CC(=C(OC2=CC(=C(O)C(=C2)I)I)C(=C1)I)I)C(O)=O",2.026,2,2,5]
["S2601","Gliclazide","c11","L3800-11","in 10mM DMSO","DMF,CFDA,PMDA,HMA","BP2019;EP9.2;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Potassium Channel","Transmembrane Transporters","Gliclazide(S1702, SE1702)  is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM.",323.41,"21187-98-4",{"v":65,"d":"65.00"},200.98,"<1","N/A","http://selleckchem.com/products/gliclazide-diamicron.html","C15H21N3O3S","free base","S1702, SE1702","CC1=CC=C(C=C1)[S](=O)(=O)NC(=O)NN2CC3CCCC3C2",1.905,3,2,3]
["S2602","Acemetacin","d11","L3800-11","in 10mM DMSO","DMF,CFDA,PMDA,HMA","BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","N/A","COX","Neuronal Signaling","Acemetacin (K-708,TVX 1322) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.",415.82,"53164-05-9",{"v":83,"d":"83.00"},199.61,"<1","N/A","http://selleckchem.com/products/acemetacin-emflex.html","C21H18ClNO6","free base","K-708,TVX 1322","COC1=CC2=C(C=C1)[N](C(=C2CC(=O)OCC(O)=O)C)C(=O)C3=CC=C(Cl)C=C3",3.942,5,0,7]
["S2603","Tioxolone","e11","L3800-11","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Carbonic Anhydrase","Metabolism","Tioxolone(Thioxolone) is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM.",168.17,"4991-65-5",{"v":34,"d":"34.00"},202.18,"<1","N/A","http://selleckchem.com/products/tioxolone.html","C7H4O3S","free base","Thioxolone","OC1=CC=C2SC(=O)OC2=C1",2.303,2,1,0]
["S2605","Idebenone","f11","L3800-11","in 10mM DMSO","DMF,EMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia","Marketed","ROS","Immunology & Inflammation","Idebenone (CV-2619) is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant.",338.44,"58186-27-9",{"v":68,"d":"68.00"},200.92,"<1","N/A","http://selleckchem.com/products/idebenone.html","C19H30O5","free base","CV-2619","COC1=C(OC)C(=O)C(=C(C)C1=O)CCCCCCCCCCO",3.836,4,1,12]
["S2606","Mifepristone (RU486)","g11","L3800-11","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","IP2010 ;Martindale:The Extra Pharmacopoeia","Marketed","Apoptosis related,Autophagy,Bcl-2,Estrogen/progestogen Receptor,Glucocorticoid Receptor","Endocrinology & Hormones","Mifepristone (RU486, C-1073, RU 38486, Mifegyne) is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.",429.59,"84371-65-3",{"v":85,"d":"85.00"},197.86,"<1","N/A","http://selleckchem.com/products/Mifepristone(Mifeprex).html","C29H35NO2","free base","RU486, C-1073, RU 38486, RU-486, Mifegyne","CC#CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C(CC12C)C5=CC=C(C=C5)N(C)C",5.655,1,0,3]
["S2607","Buflomedil HCl","h11","L3800-11","in 10mM DMSO","DMF","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Adrenergic Receptor","Neuronal Signaling","Buflomedil HCl(NSC 759291) is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease;  A nonselective alpha adrenergic receptor inhibitor.",343.85,"35543-24-9",{"v":31,"d":"31.00"},90.16,{"v":69,"d":"69.00"},200.67,"http://selleckchem.com/products/auflomedil-hcl.html","C17H25NO4.HCl","Hydrochloride","NSC 759291","Cl.COC1=CC(=C(C(=O)CCCN2CCCC2)C(=C1)OC)OC",2.939,4,0,8]
["S2608","Fluocinonide","a2","L3800-12","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;KP Ⅹ;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Glucocorticoid Receptor","Endocrinology & Hormones","Fluocinonide (Vanos,nsc 101791) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema.",494.52,"356-12-7",{"v":99,"d":"99.00"},200.19,"<1","N/A","http://selleckchem.com/products/Fluocinonide(Vanos).html","C26H32F2O7","free base","Vanos,nsc 101791","CC(=O)OCC(=O)C12OC(C)(C)OC1CC3C4CC(F)C5=CC(=O)C=CC5(C)C4(F)C(O)CC23C",1.374,6,1,4]
["S2609","Inulin","b2","L3800-12","in 10mM DMSO","FDA,DMF,PMDA","USP42-NF37;BP2010;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Inulin(Inulin and sodium chloride), a starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan.","N/A","9005-80-5",{"v":10,"d":"10.00"},{"v":10,"d":"10.00"},{"v":104,"d":"104.00"},"N/A","http://selleckchem.com/products/inulin.html","C6nH10n+2O5n+1","Free Base","N/A","OCC1OC(OC2(CO)OC(CO)C(O)C2O)C(O)C(O)C1O",-3.577,3,8,5]
["S2610","Lonidamine (AF-1890)","c2","L3800-12","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia","N/A","Carbohydrate Metabolism,Others","Metabolism","Lonidamine (AF 1890, Diclondazolic Acid, DICA) is an orally administered small molecule hexokinase inactivator.",321.16,"50264-69-2",{"v":64,"d":"64.00"},199.28,"<1","N/A","http://selleckchem.com/products/lonidamine.html","C15H10Cl2N2O2","free base","Diclondazolic Acid, DICA","OC(=O)C1=N[N](CC2=C(Cl)C=C(Cl)C=C2)C3=CC=CC=C13",{"v":4.65,"d":"4.650"},2,0,3]
["S2611","Ethisterone","d2","L3800-12","in 10mM DMSO","CFDA","N/A","N/A","Estrogen/progestogen Receptor","Endocrinology & Hormones","Ethisterone(17α-Ethynyltestosterone) is a progestogen hormone being considered to treat prostate cancer.",312.45,"434-03-7",{"v":4,"d":"4.00"},{"v":12.8,"d":"12.80"},"<1","N/A","http://www.selleck.cn/products/ethisterone.html","C21H28O2","Free Base","17α-Ethynyltestosterone","CC12CCC(=O)C=C1CCC3C2CCC4(C)C3CCC4(O)C#C",4.521,1,0,0]
["S2612","Ribitol","e2","L3800-12","in 10mM DMSO","N/A","N/A","Phase 3","Anti-infection","Microbiology","Ribitol (Adonitol) is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis.",152.15,"488-81-3",{"v":30,"d":"30.00"},197.17,{"v":30,"d":"30.00"},197.17,"http://selleckchem.com/products/ribitol-adonitol.html","C5H12O5","free base","Adonitol","OCC(O)C(O)C(O)CO",{"v":-2.43,"d":"-2.430"},0,5,4]
["S2613","Clorsulon","f2","L3800-12","in 10mM DMSO","DMF","USP42-NF37;Martindale:The Extra Pharmacopoeia","N/A","Anti-infection","Microbiology","Clorsulon (MK-401,L631529) is used in the treatment of Fasciola hepatica infections in calves and sheep.",380.66,"60200-06-8",{"v":76,"d":"76.00"},199.65,"<1","N/A","http://selleckchem.com/products/clorsulon.html","C8H8Cl3N3O4S2","free base","MK-401,L631529","NC1=CC(=C(C=C1[S](N)(=O)=O)[S](N)(=O)=O)C(Cl)=C(Cl)Cl",0.155,4,3,3]
["S2614","Arecoline HBr","g2","L3800-12","in 10mM DMSO","DMF","N/A","N/A","AChR","Neuronal Signaling","Arecoline(NSC-31750) is a muscarinic acetylcholine receptor agonist.",236.11,"300-08-3",{"v":47,"d":"47.00"},199.06,{"v":47,"d":"47.00"},199.06,"https://www.selleckchem.com/products/arecoline-hbr.html","C8H13NO2.HBr","HBr","NSC-31750","Br.COC(=O)C1=CCCN(C)C1",1.234,2,0,2]
["S2615","Noradrenaline bitartrate monohydrate","h2","L3800-12","in 10mM DMSO","CFDA","IP2010","N/A","Adrenergic Receptor","GPCR & G Protein","Noradrenaline bitartrate monohydrate (Levophed) is a direct alpha-adrenergic receptors stimulator.",337.28,"108341-18-0",{"v":64,"d":"64.00"},189.75,{"v":64,"d":"64.00"},189.75,"http://selleckchem.com/products/noradrenaline-bitartrate-monohydrate-levophed.html","C8H11NO3.C4H6O6.H2O","bitartrate monohydrate","Levophed","O.NCC(O)C1=CC(=C(O)C=C1)O.OC(C(O)C(O)=O)C(O)=O",-4.409,2,6,5]
["S2617","TAK-733","a3","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1","MEK","MAPK","TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of 3.2 nM, inactive to Abl1, AKT3, c-RAF, CamK1, CDK2, c-Met, etc. Phase 1.",504.23,"1035555-63-5",{"v":101,"d":"101.00"},200.31,"<1","N/A","http://selleckchem.com/products/tak-733.html","C17H15F2IN4O4","free base","N/A","CN1C(=O)C(=C(NC2=CC=C(I)C=C2F)C3=C1N=CN(CC(O)CO)C3=O)F",0.383,3,3,5]
["S2621","AZD5438","b3","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1","CDK","Cell Cycle","AZD5438 is a potent inhibitor of CDK1/2/9 with IC50 of 16 nM/6 nM/20 nM in cell-free assays. It is less potent to CDK5/6 and also inhibits GSK3β.",371.46,"602306-29-6",{"v":74,"d":"74.00"},199.21,"<1","N/A","http://selleckchem.com/products/AZD5438.html","C18H21N5O2S","free base","N/A","CC(C)[N]1C(=NC=C1C2=NC(=NC=C2)NC3=CC=C(C=C3)[S](C)(=O)=O)C",2.966,5,1,5]
["S2623","Omecamtiv mecarbil (CK-1827452)","c3","L3800-12","in 10mM DMSO","N/A","N/A","Phase 3","ATPase","Transmembrane Transporters","Omecamtiv mecarbil (CK-1827452) is a specific cardiac myosin activator and a clinical drug for left ventricular systolic heart failure. Phase 2.",401.43,"873697-71-3",{"v":80,"d":"80.00"},199.29,"<1","N/A","http://selleckchem.com/products/Omecamtiv-mecarbil-CK-1827452.html","C20H24FN5O3","free base","N/A","COC(=O)N1CCN(CC1)CC2=CC=CC(=C2F)NC(=O)NC3=CN=C(C)C=C3",1.794,4,2,5]
["S2624","OSI-027","d3","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","Autophagy,mTOR","PI3K/Akt/mTOR","OSI-027 (ASP4786, CERC 006, AEVI-006) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM in cell-free assays, and more than 100-fold selectivity observed for mTOR than PI3Kα, PI3Kβ, PI3Kγ or DNA-PK. OSI-027 induces autophagy in cancer cells.",406.44,"936890-98-1",{"v":18,"d":"18.00"},44.29,"<1","N/A","http://selleckchem.com/products/OSI027.html","C21H22N6O3","free base","ASP4786, CERC 006, AEVI-006","COC1=CC=CC2=C1[NH]C(=C2)C3=C4[N](N=CN=C4N)C(=N3)C5CCC(CC5)C(O)=O",3.376,5,2,4]
["S2625","Fostamatinib (R788)","e3","L3800-12","in 10mM DMSO","FDA,NDC","N/A","Marketed","Syk","Angiogenesis","Fostamatinib (R788), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.",580.46,"901119-35-5",{"v":116,"d":"116.00"},199.84,"<1","N/A","http://selleckchem.com/products/R7935788-Fostamatinib.html","C23H26FN6O9P","free base","N/A","COC1=C(OC)C(=CC(=C1)NC2=NC=C(F)C(=N2)NC3=CC=C4OC(C)(C)C(=O)N(CO[P](O)(O)=O)C4=N3)OC",3.458,9,2,10]
["S2626","Rabusertib (LY2603618)","f3","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,Autophagy,Chk","Cell Cycle","Rabusertib (LY2603618, IC-83) is a highly selective Chk1 inhibitor with potential anti-tumor activity in a cell-free assay. IC50=7 nM, showing approximately 100-fold more potent against Chk1 than against any of the other protein kinases evaluated. Rabusertib (LY2603618) induces cell cycle arrest, DNA damage response and autophagy in cancer cells. Rabusertib (LY2603618) induces bak-dependent apoptosis in AML cell lines.",{"v":436.3,"d":"436.30"},"911222-45-2",{"v":13,"d":"13.00"},{"v":29.8,"d":"29.80"},"<1","N/A","http://selleckchem.com/products/LY2603618-IC-83.html","C18H22BrN5O3","free base","IC-83","CC1=NC=C(NC(=O)NC2=C(OCC3CNCCO3)C=C(C)C(=C2)Br)N=C1",{"v":1.58,"d":"1.580"},5,3,5]
["S2631","URB597","g3","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1","FAAH","Metabolism","URB597 (KDS-4103) is a potent, orally bioavailable FAAH inhibitor with IC50 of 4.6 nM, with no activity on other cannabinoid-related targets. Phase 1.",{"v":338.4,"d":"338.40"},"546141-08-6",{"v":68,"d":"68.00"},200.95,"<1","N/A","http://selleckchem.com/products/urb597.html","C20H22N2O3","free base","KDS-4103","NC(=O)C1=CC(=CC=C1)C2=CC=CC(=C2)OC(=O)NC3CCCCC3",3.972,3,2,5]
["S2633","NPS-2143","h3","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","CaSR","GPCR & G Protein","NPS-2143 (SB262470) is a novel potent and selective antagonist of Ca(2+) receptor with IC50 of 43 nM.",408.92,"284035-33-2",{"v":82,"d":"82.00"},200.53,"<1","N/A","http://selleckchem.com/products/nps-2143.html","C24H25ClN2O2","free base","SB262470","CC(C)(CC1=CC=C2C=CC=CC2=C1)NCC(O)COC3=C(C#N)C(=CC=C3)Cl",4.844,1,2,8]
["S2634","Rebastinib (DCC-2036)","a4","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1/2","Bcr-Abl","Angiogenesis","Rebastinib (DCC-2036) is a conformational control Bcr-Abl inhibitor for Abl1(WT) and Abl1(T315I) with IC50 of 0.8 nM and 4 nM, also inhibits SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2, and low activity to seen towards c-Kit. Phase 1.",553.59,"1020172-07-9",{"v":111,"d":"111.00"},200.51,"<1","N/A","http://selleckchem.com/products/dcc-2036.html","C30H28FN7O3","free base","N/A","CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(NC(=O)NC3=CC(=N[N]3C4=CC5=C(C=C4)N=CC=C5)C(C)(C)C)C=C2)F",{"v":5.14,"d":"5.140"},6,3,7]
["S2656","PF-04929113 (SNX-5422)","b4","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","HSP (HSP90)","Cytoskeletal Signaling","PF-04929113 (SNX-5422) is a potent and selective HSP90 inhibitor with Kd of 41 nM and induces Her-2 degradation with IC50 of 37 nM. Phase 1/2.",521.53,"908115-27-5",{"v":104,"d":"104.00"},199.41,"<1","N/A","http://selleckchem.com/products/pf-04929113.html","C25H30F3N5O4","free base","N/A","CC1(C)CC(=O)C2=C(C1)[N](N=C2C(F)(F)F)C3=CC=C(C(N)=O)C(=C3)NC4CCC(CC4)OC(=O)CN",3.126,5,3,8]
["S2658","Omipalisib (GSK2126458)","c4","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1","Autophagy,mTOR,PI3K","PI3K/Akt/mTOR","Omipalisib (GSK2126458, GSK458) is a highly selective and potent inhibitor of p110α/β/δ/γ, mTORC1/2 with Ki of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM in cell-free assays, respectively. Omipalisib induces autophagy. Phase 1.",{"v":505.5,"d":"505.50"},"1086062-66-9",{"v":100,"d":"100.00"},197.82,"<1","N/A","http://selleckchem.com/products/gsk2126458.html","C25H17F2N5O3S","free base","GSK458","COC1=NC=C(C=C1N[S](=O)(=O)C2=CC=C(F)C=C2F)C3=CC=C4N=CC=C(C5=CC=NN=C5)C4=C3",3.705,7,1,6]
["S2660","MK-0752","d4","L3800-12","in 10mM DMSO","N/A","N/A","Phase 4","Beta Amyloid,Secretase","Proteases","MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM. Phase 1/2.",{"v":442.9,"d":"442.90"},"471905-41-6",{"v":89,"d":"89.00"},200.95,"<1","N/A","http://selleckchem.com/products/mk-0752.html","C21H21ClF2O4S","free base","N/A","OC(=O)CCC1CCC(CC1)(C2=C(F)C=CC(=C2)F)[S](=O)(=O)C3=CC=C(Cl)C=C3",5.615,3,0,6]
["S2664","Clinofibrate","e4","L3800-12","in 10mM DMSO","PMDA","KP Ⅹ ;JP17;Martindale:The Extra Pharmacopoeia","N/A","HMG-CoA Reductase","Metabolism","Clinofibrate inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR) with IC50 of 0.47 mM, is a lipid-lowering agent used for controlling high cholesterol and triacylglyceride levels in the blood.",468.58,"30299-08-2",{"v":94,"d":"94.00"},200.61,"<1","N/A","http://selleckchem.com/products/clinofibrate.html","C28H36O6","free base","N/A","CCC(C)(OC1=CC=C(C=C1)C2(CCCCC2)C3=CC=C(OC(C)(CC)C(O)=O)C=C3)C(O)=O",6.829,4,0,10]
["S2665","Ciprofibrate","f4","L3800-12","in 10mM DMSO","HMA","BP2019;EP9.2;CP2005;Martindale:The Extra Pharmacopoeia","Phase 3","PPAR","DNA Damage/DNA Repair","Ciprofibrate (Win-35833) is a peroxisome proliferator-activated receptor agonist.",289.15,"52214-84-3",{"v":58,"d":"58.00"},200.59,"<1","N/A","http://selleckchem.com/products/ciprofibrate.html","C13H14Cl2O3","free base","Win-35833","CC(C)(OC1=CC=C(C=C1)C2CC2(Cl)Cl)C(O)=O",2.954,2,0,4]
["S2667","Dolutegravir (GSK1349572)","g4","L3800-12","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Integrase","Microbiology","Dolutegravir (GSK1349572,S/GSK1349572,Tivicay) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM in a cell-free assay, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.",419.38,"1051375-16-6",{"v":83,"d":"83.00"},197.91,"<1","N/A","http://selleckchem.com/products/s-gsk1349572.html","C20H19F2N3O5","free base","GSK1349572,S/GSK1349572,Tivicay","CC1CCOC2CN3C=C(C(=O)NCC4=C(F)C=C(F)C=C4)C(=O)C(=C3C(=O)N12)O",{"v":0.3,"d":"0.300"},4,2,3]
["S2673","Trametinib (GSK1120212)","h4","L3800-12","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Apoptosis related,Autophagy,MEK","MAPK","Trametinib (GSK1120212, JTP-74057, Mekinist) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. Trametinib activates autophagy and induces apoptosis.",615.39,"871700-17-3",{"v":22,"d":"22.00"},35.75,"<1","N/A","http://selleckchem.com/products/gsk1120212-jtp-74057.html","C26H23FIN5O4","free base","JTP-74057, Mekinist","CN1C(=O)C(=C2N(C(=O)N(C3CC3)C(=O)C2=C1NC4=CC=C(I)C=C4F)C5=CC(=CC=C5)NC(C)=O)C",3.176,4,2,5]
["S2679","Flavopiridol (L86-8275) HCl","a5","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","Autophagy,CDK,HIV","Cell Cycle","Flavopiridol HCl (L86-8275, NSC 649890, Alvocidib, HMR-1275, DSP-2033) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM in cell-free assays. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Flavopiridol HCl induces autophagy and ER stress. Flavopiridol HCl blocks HIV-1 replication. Phase 1/2.",{"v":438.3,"d":"438.30"},"131740-09-5",{"v":88,"d":"88.00"},200.78,"<1","N/A","http://selleckchem.com/products/flavopiridol-hydrochloride.html","C21H20ClNO5.HCl","Hydrochloride","NSC 649890, Alvocidib, HMR-1275, DSP-2033","Cl.CN1CCC(C(O)C1)C2=C3OC(=CC(=O)C3=C(O)C=C2O)C4=C(Cl)C=CC=C4",{"v":3.49,"d":"3.490"},2,3,2]
["S2680","Ibrutinib (PCI-32765)","b5","L3800-12","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","BTK,Target Protein Ligand","Angiogenesis","Ibrutinib (PCI-32765,Imbruvica) is a potent and highly selective Brutons tyrosine kinase (Btk) inhibitor with IC50 of 0.5 nM in cell-free assays, modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc. Ibrutinib is applicable as a Btk ligand in the synthesis of a series of PROTACs including P13I.",{"v":440.5,"d":"440.50"},"936563-96-1",{"v":88,"d":"88.00"},199.77,"<1","N/A","http://selleckchem.com/products/pci-32765.html","C25H24N6O2","free base","PCI-32765,Imbruvica","NC1=C2C(=NC=N1)[N](N=C2C3=CC=C(OC4=CC=CC=C4)C=C3)C5CCCN(C5)C(=O)C=C",3.985,5,1,5]
["S2685","KW-2478","c5","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","HSP (HSP90)","Cytoskeletal Signaling","KW-2478 is a nonansamycin HSP90 inhibitor with IC50 of 3.8 nM. Phase 1.",574.66,"819812-04-9",{"v":115,"d":"115.00"},200.12,"<1","N/A","http://selleckchem.com/products/kw-2478.html","C30H42N2O9","free base","N/A","CCC1=C(CC(=O)N(CCOC)CCOC)C(=C(O)C=C1O)C(=O)C2=CC=C(OCCN3CCOCC3)C(=C2)OC",2.673,7,2,16]
["S2688","R547","d5","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1","CDK","Cell Cycle","R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1.",441.45,"741713-40-6",{"v":60,"d":"60.00"},135.92,"<1","N/A","http://selleckchem.com/products/r547.html","C18H21F2N5O4S","free base","Ro 4584820","COC1=CC=C(F)C(=C1C(=O)C2=C(N)N=C(NC3CCN(CC3)[S](C)(=O)=O)N=C2)F",1.133,6,2,6]
["S2693","Resminostat","e5","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","HDAC","Epigenetics","Resminostat (RAS2410) dose-dependently and selectively inhibits HDAC1/3/6 with IC50 of 42.5 nM/50.1 nM/71.8 nM, less potent to HDAC8 with IC50 of 877 nM.",{"v":349.4,"d":"349.40"},"864814-88-0",{"v":70,"d":"70.00"},200.34,"<1","N/A","http://selleckchem.com/products/resminostat-ras2410.html","C16H19N3O4S","free base","RAS2410","CN(C)CC1=CC=C(C=C1)[S](=O)(=O)[N]2C=CC(=C2)\\C=C\\C(=O)NO",1.837,3,1,6]
["S2694","Turofexorate Isopropyl (XL335)","f5","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1","FXR","Metabolism","Turofexorate Isopropyl (XL335, Fxr 450) is a potent, selective FXR agonist with EC50 of 4 nM, highly selective versus other nuclear receptors, such as LXR, PPAR, ER and etc. Phase 1.",438.47,"629664-81-9",{"v":33,"d":"33.00"},75.26,"<1","N/A","http://selleckchem.com/products/way-362450.html","C25H24F2N2O3","free base","Fxr 450","CC(C)OC(=O)C1=CN(CC(C)(C)C2=C1[NH]C3=CC=CC=C23)C(=O)C4=CC=C(F)C(=C4)F",4.968,3,1,4]
["S2695","Nepicastat (SYN-117) HCl","g5","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","Hydroxylase","Metabolism","Nepicastat (SYN-117) HCl is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. Phase 2.",331.81,"170151-24-3",{"v":66,"d":"66.00"},198.91,"<1","N/A","http://selleckchem.com/products/nepicastat-hydrochloride.html","C14H15F2N3S.HCl","Hydrochloride","N/A","Cl.NCC1=CNC(=S)N1C2CCC3=C(F)C=C(F)C=C3C2",3.008,0,2,2]
["S2696","Apitolisib (GDC-0980)","h5","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,Autophagy,mTOR,PI3K","PI3K/Akt/mTOR","Apitolisib (GDC-0980, RG7422, GNE 390) is a potent, class I PI3K inhibitor for PI3Kα/β/δ/γ with IC50 of 5 nM/27 nM/7 nM/14 nM in cell-free assays, respectively. Also a mTOR inhibitor with Ki of 17 nM in a cell-free assay, and highly selective versus other PIKK family kinases. Apitolisib activates autophagy and apoptosis simultaneously in pancreatic cancer cells. Phase 2.",{"v":498.6,"d":"498.60"},"1032754-93-0",{"v":20,"d":"20.00"},40.11,"<1","N/A","http://selleckchem.com/products/GDC-0980-RG7422.html","C23H30N8O3S","free base","RG7422, GNE 390","CC(O)C(=O)N1CCN(CC1)CC2=C(C)C3=NC(=NC(=C3S2)N4CCOCC4)C5=CN=C(N)N=C5",1.013,6,2,5]
["S2698","RS-127445","a6","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1","5-HT Receptor","Neuronal Signaling","RS-127445 (MT500) is a selective 5-HT2B receptor antagonist with pKi of 9.5 and pIC50 of 10.4, exhibits >1000-fold selectivity against other 5-HT receptors.",281.33,"199864-87-4",{"v":56,"d":"56.00"},199.05,"<1","N/A","http://selleckchem.com/products/rs-127445.html","C17H16FN3","free base","MT500","CC(C)C1=NC(=NC(=C1)C2=C3C=CC=CC3=C(F)C=C2)N",4.298,2,1,2]
["S2699","CH5132799","b6","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1","PI3K","PI3K/Akt/mTOR","CH5132799 (MEN1611, PA799) inhibits class I PI3Ks, particularly PI3Kα with IC50 of 14 nM; less potent to PI3Kβδγ, while sensitive in PIK3CA mutations cell lines. Phase 1.",377.42,"1007207-67-1",{"v":12,"d":"12.00"},31.79,"<1","N/A","http://selleckchem.com/products/ch5132799.html","C15H19N7O3S","free base","MEN1611, PA799","C[S](=O)(=O)N1CCC2=C(N=C(N=C12)N3CCOCC3)C4=CN=C(N)N=C4",0.095,7,1,3]
["S2700","Tirbanibulin","c6","L3800-12","in 10mM DMSO","N/A","N/A","Phase 3","Src","Angiogenesis","Tirbanibulin(KX2-391,KX 01), the first clinical Src inhibitor (peptidomimetic class) that targets the peptide substrate site of Src, with GI50 of 9-60 nM in cancer cell lines. Phase 2.",431.53,"897016-82-9",{"v":86,"d":"86.00"},199.29,"<1","N/A","http://selleckchem.com/products/kx2-391.html","C26H29N3O3","free base","KX2-391,KX 01","O=C(CC1=CC=C(C=N1)C2=CC=C(OCCN3CCOCC3)C=C2)NCC4=CC=CC=C4",3.262,4,1,9]
["S2713","Geldanamycin (NSC 122750)","d6","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","Antineoplastic and Immunosuppressive Antibiotics,Antiviral,Autophagy,HSP (HSP90)","Cytoskeletal Signaling","Geldanamycin (NSC 122750) is a natural existing HSP90 inhibitor with Kd of 1.2 μM, specifically disrupts glucocorticoid receptor (GR)/HSP association. Geldanamycin attenuates virus infection-induced ALI (acute lung injury)/ARDS (acute respiratory distress syndrome) by reducing the host's inflammatory responses.",560.64,"30562-34-6",{"v":36,"d":"36.00"},64.21,"<1","N/A","http://selleckchem.com/products/geldanamycin.html","C29H40N2O9","free base","NSC 122750","COC1CC(C)CC2=C(OC)C(=O)C=C(NC(=O)\\C(=C\\C=C\\C(OC)C(OC(N)=O)\\C(=C\\C(C)C1O)C)C)C2=O",{"v":2.36,"d":"2.360"},8,3,5]
["S2718","TAK-901","e6","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1","Aurora Kinase","Cell Cycle","TAK-901 is a novel inhibitor of Aurora A/B with IC50 of 21 nM/15 nM. It is not a potent inhibitor of cellular JAK2, c-Src or Abl. Phase 1.",504.64,"934541-31-8",{"v":101,"d":"101.00"},200.14,"<1","N/A","http://selleckchem.com/products/tak-901.html","C28H32N4O3S","free base","N/A","CC[S](=O)(=O)C1=CC=CC(=C1)C2=CC(=C(C)C3=C2C4=C([NH]3)N=CC(=C4)C)C(=O)NC5CCN(C)CC5",4.056,4,2,5]
["S2719","AMG-900","f6","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1","Aurora Kinase","Cell Cycle","AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM. It is >10-fold selective for Aurora kinases than p38α, Tyk2, JNK2, Met and Tie2. Phase 1.",503.58,"945595-80-2",{"v":100,"d":"100.00"},198.58,"<1","N/A","http://selleckchem.com/products/amg-900.html","C28H21N7OS","free base","N/A","CC1=CSC(=C1)C2=NN=C(NC3=CC=C(OC4=C(C=CC=N4)C5=NC(=NC=C5)N)C=C3)C6=C2C=CC=C6",6.487,6,2,6]
["S2721","Nilvadipine","g6","L3800-12","in 10mM DMSO","DMF,PMDA","JP17;Martindale:The Extra Pharmacopoeia","Phase 3","Calcium Channel","Transmembrane Transporters","Nilvadipine (ARC029, FR34235,FK235) is a potent calcium channel blocker with an IC50 of 0.03 nM.",385.37,"75530-68-6",{"v":77,"d":"77.00"},199.81,"<1","N/A","http://selleckchem.com/products/nilvadipine-arc029.html","C19H19N3O6","free base","ARC029, FR34235,FK235","COC(=O)C1=C(NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OC(C)C)C)C#N",2.087,4,1,7]
["S2722","JTC-801","h6","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","Opioid Receptor","Neuronal Signaling","JTC-801 is a selective opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM, weakly inhibits receptors δ, κ, and μ.",447.96,"244218-51-7",{"v":90,"d":"90.00"},200.91,"<1","N/A","http://selleckchem.com/products/jtc-801.html","C26H25N3O2.HCl","Hydrochloride","N/A","Cl.CCC1=CC=C(OCC2=CC=CC=C2C(=O)NC3=CC4=C(C=C3)N=C(C)C=C4N)C=C1",5.228,3,2,6]
["S2726","PH-797804","a7","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","p38 MAPK","MAPK","PH-797804 is a novel pyridinone inhibitor of p38α with IC50 of 26 nM in a cell-free assay; 4-fold more selective versus p38β and does not inhibit JNK2. Phase 2.",{"v":477.3,"d":"477.30"},"586379-66-0",{"v":96,"d":"96.00"},201.13,"<1","N/A","http://selleckchem.com/products/ph-797804.html","C22H19BrF2N2O3","free base","N/A","CNC(=O)C1=CC(=C(C)C=C1)N2C(=CC(=C(Br)C2=O)OCC3=CC=C(F)C=C3F)C",3.801,3,1,5]
["S2727","Dacomitinib (PF-00299804)","b7","L3800-12","in 10mM DMSO","FDA,NDC","N/A","Registered","Apoptosis related,EGFR,HER2","Protein Tyrosine Kinase","Dacomitinib (PF299804, PF299) is a potent, irreversible pan-ErbB inhibitor, mostly to EGFR with IC50 of 6 nM in a cell-free assay. Dacomitinib inhibits ERBB2 and ERBB4 with IC50 of 45.7 nM and 73.7 nM, respectively. Dacomitinib is effective against NSCLCs with EGFR or ERBB2 mutations (resistant to gefitinib) as well as those harboring the EGFR T790M mutation. Dacomitinib inhibits cell growth and induces apoptosis. Phase 2.",469.94,"1110813-31-4",{"v":19,"d":"19.00"},40.43,"<1","N/A","http://selleckchem.com/products/pf299804.html","C24H25ClFN5O2","free base","PF299804,PF299","COC1=C(NC(=O)/C=C/CN2CCCCC2)C=C3C(=NC=NC3=C1)NC4=CC(=C(F)C=C4)Cl",5.055,4,2,7]
["S2730","Crenolanib (CP-868596)","c7","L3800-12","in 10mM DMSO","N/A","N/A","Phase 3","FLT3,Mitophagy,PDGFR","Protein Tyrosine Kinase","Crenolanib (CP-868596, ARO 002) is a potent and selective inhibitor of PDGFRα/β with Kd of 2.1 nM/3.2 nM in CHO cells, also potently inhibits FLT3, sensitive to D842V mutation not V561D mutation, >100-fold more selective for PDGFR than c-Kit, VEGFR-2, TIE-2, FGFR-2, EGFR, erbB2, and Src. Crenolanib helps to induce mitophagy.",443.54,"670220-88-9",{"v":88,"d":"88.00"},{"v":198.4,"d":"198.40"},"<1","N/A","http://selleckchem.com/products/crenolanib-cp-868596.html","C26H29N5O2","free base","ARO 002","CC1(COC1)COC2=CC3=C(C=C2)[N](C=N3)C4=NC5=C(C=CC=C5C=C4)N6CCC(N)CC6",3.192,4,1,5]
["S2736","Fedratinib (TG101348)","d7","L3800-12","in 10mM DMSO","N/A","N/A","Phase 3","Apoptosis related,c-RET,FLT3,JAK","JAK/STAT","Fedratinib (SAR302503, TG101348) is a selective inhibitor of JAK2 with IC50 of 3 nM in cell-free assays, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3. Fedratinib also inhibits FMS-like tyrosine kinase 3 (FLT3) and RET (c-RET) with IC50 of 15 nM and 48 nM, respectively. Fedratinib has potential antineoplastic activity. Fedratinib inhibits proliferation and induces apoptosis. Phase 2.",524.68,"936091-26-8",{"v":100,"d":"100.00"},190.59,"<1","N/A","http://selleckchem.com/products/Fedratinib-SAR302503-TG101348.html","C27H36N6O3S","free base","SAR302503","CC1=C(NC2=CC=CC(=C2)[S](=O)(=O)NC(C)(C)C)N=C(NC3=CC=C(OCCN4CCCC4)C=C3)N=C1",5.123,5,3,11]
["S2738","PAC-1","e7","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","Caspase","Apoptosis","PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM and the first small molecule known to directly activate procaspase-3 to caspase-3.",392.49,"315183-21-2",{"v":78,"d":"78.00"},198.73,"<1","N/A","http://selleckchem.com/products/pac-1.html","C23H28N4O2","free base","N/A","OC1=C(CC=C)C=CC=C1/C=N/NC(=O)CN2CCN(CC2)CC3=CC=CC=C3",3.331,2,2,8]
["S2740","GSK1070916","f7","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","Aurora Kinase","Cell Cycle","GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. Phase 1.",507.63,"942918-07-2",{"v":93,"d":"93.00"},{"v":183.2,"d":"183.20"},"<1","N/A","http://selleckchem.com/products/gsk1070916.html","C30H33N7O","free base","N/A","CC[N]1C=C(C2=C3C=C([NH]C3=NC=C2)C4=CC=CC(=C4)CN(C)C)C(=N1)C5=CC=C(NC(=O)N(C)C)C=C5",4.841,3,2,7]
["S2741","Niraparib (MK-4827)","g7","L3800-12","in 10mM DMSO","FDA,EMA,NDC","N/A","Marketed","Apoptosis related,PARP","DNA Damage/DNA Repair","Niraparib (MK-4827) is a selective inhibitor of PARP1/2 with IC50 of 3.8 nM/2.1 nM, with great activity in cancer cells with mutant BRCA-1 and BRCA-2. It is >330-fold selective against PARP3, V-PARP and Tank1. Niraparib can form PARP–DNA complexes resulting in DNA damage, apoptosis, and cell death. Phase 3.",320.39,"1038915-60-4",{"v":64,"d":"64.00"},199.76,"<1","N/A","http://selleckchem.com/products/mk-4827.html","C19H20N4O","Free Base","N/A","NC(=O)C1=CC=CC2=C[N](N=C12)C3=CC=C(C=C3)C4CCCNC4",2.618,2,2,3]
["S2743","PF-04691502","h7","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","Akt,Apoptosis related,mTOR,PI3K","PI3K/Akt/mTOR","PF-04691502 (PF4691502) is an ATP-competitive PI3K(α/β/δ/γ)/mTOR dual inhibitor with Ki of 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM in cell-free assays, little activity against either Vps34, AKT, PDK1, p70S6K, MEK, ERK, p38, or JNK. PF-04691502 induces apoptosis. Phase 2.",425.48,"1013101-36-4",{"v":14,"d":"14.00"},{"v":32.9,"d":"32.90"},"<1","N/A","http://selleckchem.com/products/pf-04691502.html","C22H27N5O4","free base","PF4691502","COC1=CC=C(C=N1)C2=CC3=C(C)N=C(N)N=C3N(C4CCC(CC4)OCCO)C2=O",1.616,6,2,6]
["S2748","Anacetrapib (MK-0859)","a8","L3800-12","in 10mM DMSO","N/A","N/A","Phase 3","CETP,LDL","Metabolism","Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Phase 3.",637.51,"875446-37-0",{"v":127,"d":"127.00"},199.21,"<1","N/A","http://selleckchem.com/products/anacetrapib-mk-0859.html","C30H25F10NO3","free base","N/A","COC1=CC(=C(C=C1C2=CC=C(C=C2CN3C(C)C(OC3=O)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F)C(F)(F)F)C(C)C)F",9.343,3,0,9]
["S2749","BGT226 (NVP-BGT226) maleate","b8","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","mTOR,PI3K","PI3K/Akt/mTOR","BGT226 (NVP-BGT226) maleate is a novel class I PI3K/mTOR inhibitor for PI3Kα/β/γ with IC50 of 4 nM/63 nM/38 nM. Phase 1/2.",{"v":650.6,"d":"650.60"},"1245537-68-1",{"v":30,"d":"30.00"},46.11,"<1","N/A","http://selleckchem.com/products/nvp-bgt226.html","C28H25F3N6O2.C4H4O","maleate","N/A","COC1=NC=C(C=C1)C2=CC=C3N=CC4=C(N(C(=O)N4C)C5=CC(=C(C=C5)N6CCNCC6)C(F)(F)F)C3=C2.OC(=O)\\C=C/C(O)=O",1.618,6,1,7]
["S2751","Milciclib (PHA-848125)","c8","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","Autophagy,CDK","Cell Cycle","Milciclib (PHA-848125) is a potent, ATP-competitive CDK inhibitor for CDK2 with IC50 of 45 nM. It is >3-fold more selective for CDK2 than CDK1, 2, 4, 5, and 7, it's also an inhibitor of TRKA with IC50 of 53nM. Milciclib (PHA-848125) induces cell death through autophagy. Phase 2.",460.57,"802539-81-7",{"v":92,"d":"92.00"},199.75,"<1","N/A","http://selleckchem.com/products/pha-848125.html","C25H32N8O","free base","N/A","CNC(=O)C1=N[N](C)C2=C1C(C)(C)CC3=CN=C(NC4=CC=C(C=C4)N5CCN(C)CC5)N=C23",3.825,4,2,4]
["S2752","HER2-Inhibitor-1","d8","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1","EGFR,HER2","Protein Tyrosine Kinase","HER2-Inhibitor-1 is an analog of ARRY-380. ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR.",569.63,"937265-83-3",{"v":100,"d":"100.00"},175.55,"<1","N/A","http://selleckchem.com/products/her2-inhibitor-1.html","C29H27N7O4S","free base","N/A","CC1=CC(=CC=C1OC2=CC3=NC=N[N]3C=C2)NC4=C5C=C(C=CC5=NC=N4)C6=CC=C(CNCC[S](C)(=O)=O)O6",4.446,8,2,10]
["S2753","Tivantinib (ARQ 197)","e8","L3800-12","in 10mM DMSO","N/A","N/A","Phase 3","Apoptosis related,c-Met","Protein Tyrosine Kinase","Tivantinib (ARQ 197) is the first non-ATP-competitive c-Met inhibitor with Ki of 0.355 μM in a cell-free assay, little activity to Ron, and no inhibition to EGFR, InsR, PDGFRα or FGFR1/4. Tivantinib (ARQ 197) induces a G2/M arrest and apoptosis.",369.42,"905854-02-6",{"v":73,"d":"73.00"},197.61,"<1","N/A","http://selleckchem.com/products/arq-197.html","C23H19N3O2","free base","N/A","O=C1NC(=O)C(C1C2=C[NH]C3=C2C=CC=C3)C4=C[N]5CCCC6=CC=CC4=C56",{"v":3.52,"d":"3.520"},2,2,2]
["S2754","Xevinapant (AT406)","f8","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","E3 Ligase ,IAP","Apoptosis","Xevinapant (AT406, ARRY-334543, Debio1143, SM-406) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.",561.71,"1071992-99-8",{"v":100,"d":"100.00"},178.03,"<1","N/A","http://selleckchem.com/products/at-406.html","C32H43N5O4","free base","ARRY-334543, Debio1143, SM-406","CNC(C)C(=O)NC1CN(CCC2CCC(N2C1=O)C(=O)NC(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)CC(C)C",2.264,4,3,9]
["S2755","Varlitinib","g8","L3800-12","in 10mM DMSO","N/A","N/A","Phase 3","EGFR","Protein Tyrosine Kinase","Varlitinib (ARRY334543) is a selective and potent ErbB1(EGFR) and ErbB2(HER2) inhibitor with IC50 of 7 nM and 2 nM, respectively. Phase 2.",466.94,"845272-21-1",{"v":6,"d":"6.00"},12.85,"<1","N/A","http://selleckchem.com/products/arry334543.html","C22H19ClN6O2S","free base","ARRY334543","CC1COC(=N1)NC2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(OCC5=NC=CS5)C=C4)Cl",4.577,6,2,7]
["S2757","Evofosfamide (TH-302)","h8","L3800-12","in 10mM DMSO","N/A","N/A","Phase 3","Others","Others","Evofosfamide (TH-302) is a selective hypoxia-activated prodrug targeting hypoxic regions of solid tumors with IC50 of 19 nM, demonstrates 270-fold enhanced cytotoxicity under hypoxia versus their potency under aerobic conditions, stable to cytochrome P450 metabolism.",449.04,"918633-87-1",{"v":90,"d":"90.00"},200.43,{"v":10,"d":"10.00"},22.27,"http://selleckchem.com/products/th-302.html","C9H16Br2N5O4P","free base","Evofosfamide","C[N]1C(=CN=C1[N+]([O-])=O)CO[P](=O)(NCCBr)NCCBr",0.537,3,2,10]
["S2759","Fimepinostat (CUDC-907)","a9","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,HDAC,PI3K","Cytoskeletal Signaling","CUDC-907 is a dual PI3K and HDAC inhibitor for PI3Kα and HDAC1/2/3/10 with IC50 of 19 nM and 1.7 nM/5 nM/1.8 nM/2.8 nM, respectively. CUDC-907 induces cell cycle arrest and apoptosis in breast cancer cells. Phase 1.",508.55,"1339928-25-4",{"v":102,"d":"102.00"},200.57,"<1","N/A","http://selleckchem.com/products/pi3k-hdac-inhibitor-i.html","C23H24N8O4S","free base","N/A","COC1=CC=C(C=N1)C2=NC3=C(SC(=C3)CN(C)C4=NC=C(C=N4)C(=O)NO)C(=N2)N5CCOCC5",2.303,8,1,7]
["S2760","Canagliflozin (JNJ 28431754)","b9","L3800-12","in 10mM DMSO","FDA,DMF,EMA,NDC","N/A","Marketed","SGLT","GPCR & G Protein","Canagliflozin (TA 7284, JNJ 28431754) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM in a cell-free assay, exhibits 413-fold selectivity over hSGLT1.",444.52,"842133-18-0",{"v":88,"d":"88.00"},197.97,"<1","N/A","http://selleckchem.com/products/canagliflozin.html","C24H25FO5S","free base","TA 7284","CC1=C(CC2=CC=C(S2)C3=CC=C(F)C=C3)C=C(C=C1)C4OC(CO)C(O)C(O)C4O",3.446,1,4,5]
["S2762","Alectinib (CH5424802)","c9","L3800-12","in 10mM DMSO","FDA,DMF,EMA,NDC","N/A","Marketed","ALK","Protein Tyrosine Kinase","Alectinib (CH5424802, AF-802, RG-7853) is a potent ALK inhibitor with IC50 of 1.9 nM in cell-free assays, sensitive to L1196M mutation and higher selectivity for ALK than PF-02341066, NVP-TAE684 and PHA-E429.",482.62,"1256580-46-7",{"v":6,"d":"6.00"},12.43,{"v":1,"d":"1.00"},2.07,"http://www.selleckchem.com/products/ch5424802.html","C30H34N4O2","Free Base","AF-802, RG-7853,CH5424802","CCC1=CC2=C(C=C1N3CCC(CC3)N4CCOCC4)C(C)(C)C5=C(C2=O)C6=CC=C(C=C6[NH]5)C#N",5.203,2,1,3]
["S2765","MK-2048","d9","L3800-12","in 10mM DMSO","DMF","N/A","N/A","Integrase","Microbiology","MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.",461.87,"869901-69-9",{"v":9,"d":"9.00"},19.49,"<1","N/A","http://selleckchem.com/products/mk-2048.html","C21H21ClFN5O4","free base","N/A","CCN1CC(C)[N]2C(=C(O)C3=C2C(=NN(CC4=CC=C(F)C(=C4)Cl)C3=O)C(=O)NC)C1=O",2.446,4,2,4]
["S2768","Dinaciclib (SCH727965)","e9","L3800-12","in 10mM DMSO","N/A","N/A","Phase 3","Caspase,CDK","Cell Cycle","Dinaciclib (SCH727965, PS-095760) is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM in cell-free assays, respectively. It also blocks thymidine (dThd) DNA incorporation. Dinaciclib induces apoptosis through the activation of caspases 8 and 9. Phase 3.",396.49,"779353-01-4",{"v":26,"d":"26.00"},65.58,"<1","N/A","http://selleckchem.com/products/dinaciclib-sch727965.html","C21H28N6O2","free base","PS-095760","CCC1=C2N=C(C=C(NCC3=CC=C[N+](=C3)[O-])[N]2N=C1)N4CCCCC4CCO",2.152,2,2,7]
["S2770","MK-5108 (VX-689)","f9","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1","Aurora Kinase,Autophagy","Cell Cycle","MK-5108 (VX-689) is a highly selective Aurora A inhibitor with IC50 of 0.064 nM in a cell-free assay and is 220- and 190-fold more selective for Aurora A than Aurora B/C, while it inhibits TrkA with less than 100-fold selectivity. MK-5108 (VX-689) induces autophagy. Phase 1.",461.94,"1010085-13-8",{"v":92,"d":"92.00"},199.16,"<1","N/A","http://selleckchem.com/products/mk-5108-vx-689.html","C22H21ClFN3O3S","free base","N/A","OC(=O)C1(CCC(CC1)OC2=C(F)C(=CC=C2)Cl)CC3=CC=CC(=N3)NC4=NC=CS4",5.574,4,1,7]
["S2772","Dalcetrapib (JTT-705)","g9","L3800-12","in 10mM DMSO","N/A","N/A","Phase 3","CETP","Metabolism","Dalcetrapib (JTT-705) is a rhCETP inhibitor with IC50 of 0.2 μM that increases the plasma HDL cholesterol. Phase 3.",389.59,"211513-37-0",{"v":78,"d":"78.00"},200.21,"<1","N/A","http://selleckchem.com/products/dalcetrapib-jtt-705.html","C23H35NO2S","free base","RO4607381","CCC(CC)CC1(CCCCC1)C(=O)NC2=C(SC(=O)C(C)C)C=CC=C2",7.025,2,1,9]
["S2773","SB705498","h9","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","TRP Channel","Transmembrane Transporters","SB705498 is a TRPV1 antagonist for hTRPV1, antagonizes capsaicin, acid, and heat activation of TRPV1 with IC50 of 3 nM, 0.1 nM and 6 nM, shows a degree of voltage dependence, exhibits >100-fold selectivity for TRPV1 over TRPM8. Phase 2.",429.23,"501951-42-4",{"v":86,"d":"86.00"},200.36,"<1","N/A","http://selleckchem.com/products/sb705498.html","C17H16BrF3N4O","free base","N/A","FC(F)(F)C1=CN=C(C=C1)N2CCC(C2)NC(=O)NC3=CC=CC=C3Br",3.745,2,2,4]
["S2774","MK-2461","a10","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","c-Met,FGFR,PDGFR,RON","Protein Tyrosine Kinase","MK-2461 is a potent, multi-targeted inhibitor for c-Met(WT/mutants) with IC50 of 0.4-2.5 nM, less potent to Ron, Flt1; 8- to 30-fold greater selectivity of c-Met targets versus FGFR1, FGFR2, FGFR3, PDGFRβ, KDR, Flt3, Flt4, TrkA, and TrkB. Phase 1/2.",495.55,"917879-39-1",{"v":99,"d":"99.00"},199.78,"<1","N/A","http://selleckchem.com/products/mk-2461.html","C24H25N5O5S","free base","N/A","CN(CC1COCCO1)[S](=O)(=O)NC2=CC3=C(C=C2)C=CC4=C(C=C(C=N4)C5=C[N](C)N=C5)C3=O",0.924,7,1,6]
["S2776","Devimistat (CPI-613)","b10","L3800-12","in 10mM DMSO","N/A","N/A","Phase 3","Apoptosis related,Dehydrogenase","Metabolism","Devimistat (CPI-613), a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase in NCI-H460 cell line, disrupts tumor cell mitochondrial metabolism. CPI-613 induces apoptosis in pancreatic cancer cells. Phase 2.",388.59,"95809-78-2",{"v":77,"d":"77.00"},198.15,"<1","N/A","http://selleckchem.com/products/cpi-613.html","C22H28O2S2","free base","N/A","OC(=O)CCCCC(CCSCC1=CC=CC=C1)SCC2=CC=CC=C2",{"v":5.63,"d":"5.630"},1,0,13]
["S2778","GW842166X","c10","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","Cannabinoid Receptor","GPCR & G Protein","GW842166X is a potent and highly selective agonist of cannabinoid receptor CB2 receptor with EC50 of 63 nM, shows no significant activity at CB1 receptor. Phase 2.",449.25,"666260-75-9",{"v":20,"d":"20.00"},44.52,"<1","N/A","http://selleckchem.com/products/gw-842166x.html","C18H17Cl2F3N4O2","free base","N/A","FC(F)(F)C1=NC(=NC=C1C(=O)NCC2CCOCC2)NC3=CC=C(Cl)C=C3Cl",4.449,4,2,6]
["S2783","Vistusertib (AZD2014)","d10","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,Autophagy,mTOR","PI3K/Akt/mTOR","Vistusertib (AZD2014) is a novel mTOR inhibitor with IC50 of 2.8 nM in a cell-free assay; highly selective against multiple PI3K isoforms (α/β/γ/δ). AZD2014 showed no or weak binding to the majority of kinases when tested at 1 μM. AZD2014 induces proliferation suppression, apoptosis, cell cycle arrest, and autophagy in HCC cells with antitumor activity.",462.54,"1009298-59-2",{"v":38,"d":"38.00"},82.16,"<1","N/A","http://selleckchem.com/products/azd2014.html","C25H30N6O3","free base","N/A","CNC(=O)C1=CC=CC(=C1)C2=CC=C3C(=N2)N=C(N=C3N4CCOCC4C)N5CCOCC5C",3.103,6,1,4]
["S2784","TAK-285","e10","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1","EGFR,HER2","Protein Tyrosine Kinase","TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.",547.96,"871026-44-7",{"v":110,"d":"110.00"},200.74,"<1","N/A","http://selleckchem.com/products/tak-285.html","C26H25ClF3N5O3","free base","N/A","CC(C)(O)CC(=O)NCC[N]1C=CC2=C1C(=NC=N2)NC3=CC=C(OC4=CC=CC(=C4)C(F)(F)F)C(=C3)Cl",5.586,4,2,10]
["S2787","Laquinimod","f10","L3800-12","in 10mM DMSO","EMA","N/A","Marketed","Immunology & Inflammation related","Immunology & Inflammation","Laquinimod (ABR-215062, LAQ) is a potent immunomodulator. Phase 3.",{"v":356.8,"d":"356.80"},"248281-84-7",{"v":61,"d":"61.00"},170.96,"<1","N/A","http://selleckchem.com/products/laquinimod-abr-215062.html","C19H17ClN2O3","free base","ABR-215062, LAQ","CCN(C(=O)C1=C(O)C2=C(C=CC=C2Cl)N(C)C1=O)C3=CC=CC=C3",2.884,2,1,3]
["S2789","Tofacitinib (CP-690550)","g10","L3800-12","in 10mM DMSO","FDA,DMF,EMA,NDC","N/A","Marketed","Apoptosis related,JAK","JAK/STAT","Tofacitinib (CP-690550,Tasocitinib) is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1. Tofacitinib inhibits the expression of antiapoptotic BCL-A1 and BCL-XL in human plasmacytoid dendritic cells (PDC) and induced PDC apoptosis.",312.37,"477600-75-2",{"v":62,"d":"62.00"},198.48,"<1","N/A","http://selleckchem.com/products/tofacitinib-cp-690550.html","C16H20N6O","free base","Tasocitinib","CC1CCN(CC1N(C)C2=C3C=C[NH]C3=NC=N2)C(=O)CC#N",1.512,3,1,3]
["S2790","Istradefylline","h10","L3800-12","in 10mM DMSO","DMF,PMDA","N/A","Marketed","Adenosine Receptor","GPCR & G Protein","Istradefylline (KW-6002) is a selective adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. Phase 3.",384.43,"155270-99-8",{"v":6,"d":"6.00"},15.61,"<1","N/A","http://selleckchem.com/products/istradefylline-kw-6002.html","C20H24N4O4","free base","KW-6002","CCN1C(=O)N(CC)C2=C([N](C)C(=N2)\\C=C\\C3=CC=C(OC)C(=C3)OC)C1=O",2.957,5,0,6]
["S2791","Sotrastaurin (AEB071)","a11","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1/2","PKC","TGF-beta/Smad","Sotrastaurin (AEB071) is a potent and selective pan-PKC inhibitor, mostly for PKCθ with Ki of 0.22 nM in a cell-free assay; inactive to PKCζ. Phase 2.",438.48,"425637-18-9",{"v":87,"d":"87.00"},198.41,"<1","N/A","http://selleckchem.com/products/sotrastaurin-aeb071.html","C25H22N6O2","free base","AEB071","CN1CCN(CC1)C2=NC(=C3C=CC=CC3=N2)C4=C(C(=O)NC4=O)C5=C[NH]C6=C5C=CC=C6",3.483,4,2,3]
["S2792","Torcetrapib","b11","L3800-12","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","CETP","Metabolism","Torcetrapib (CP-529414) is a CETP inhibitor with IC50 of 37 nM, elevates HDL-C and reduces nonHDL-C in plasma. Phase 3.",600.47,"262352-17-0",{"v":120,"d":"120.00"},199.84,"<1","N/A","http://selleckchem.com/products/torcetrapib-cp-529414.html","C26H25F9N2O4","free base","CP-529414","CCOC(=O)N1C(CC)CC(N(CC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)C(=O)OC)C3=C1C=CC(=C3)C(F)(F)F",7.345,4,0,10]
["S2794","Sofosbuvir (GS-7977)","c11","L3800-12","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","DNA/RNA Synthesis,HCV Protease","DNA Damage/DNA Repair","Sofosbuvir (PSI-7977, GS-7977) is a HCV NS5B polymerase inhibitor for the treatment of chronic hepatitis C virus (HCV) infection.",529.45,"1190307-88-0",{"v":100,"d":"100.00"},188.88,{"v":11,"d":"11.00"},20.78,"http://selleckchem.com/products/psi-7977-gs-7977.html","C22H29FN3O9P","free base","PSI-7977","CC(C)OC(=O)C(C)N[P](=O)(OCC1OC(N2C=CC(=O)NC2=O)C(C)(F)C1O)OC3=CC=CC=C3",0.921,7,3,11]
["S2796","WP1066","d11","L3800-12","in 10mM DMSO","N/A","N/A","Phase 1/2","Apoptosis related,JAK,STAT","JAK/STAT","WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2 not JAK1 and JAK3. WP1066 induces apoptosis. Phase 1.",356.22,"857064-38-1",{"v":71,"d":"71.00"},199.32,"<1","N/A","http://selleckchem.com/products/wp1066.html","C17H14BrN3O","free base","N/A","CC(NC(=O)\\C(=C\\C1=NC(=CC=C1)Br)C#N)C2=CC=CC=C2",3.566,2,1,4]
["S2797","Lonafarnib (SCH66336)","e11","L3800-12","in 10mM DMSO","N/A","N/A","Phase 3","Ras,Transferase","Metabolism","Lonafarnib (SCH66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM in cell-free assays, respectively. Phase 3.",638.82,"193275-84-2",{"v":127,"d":"127.00"},{"v":198.8,"d":"198.80"},"<1","N/A","http://selleckchem.com/products/lonafarnib-sch66336.html","C27H31Br2ClN4O2","free base","SCH66336","NC(=O)N1CCC(CC1)CC(=O)N2CCC(CC2)C3C4=C(CCC5=C3C(=CC(=C5)Cl)Br)C=C(Br)C=N4",5.271,3,1,3]
["S2799","Daporinad","f11","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2","Autophagy,NAMPT,Transferase","Metabolism","Daporinad (FK866, APO866) effectively inhibits nicotinamide phosphoribosyltransferase (NMPRTase; Nampt) with IC50 of 0.09 nM in a cell-free assay. Daporinad (FK866, APO866) triggers autophagy. Phase 1/2.",391.51,"658084-64-1",{"v":78,"d":"78.00"},199.23,"<1","N/A","http://www.selleck.cn/products/apo866-fk866.html","C24H29N3O2","Free Base","FK866, APO866","O=C(NCCCCC1CCN(CC1)C(=O)C2=CC=CC=C2)/C=C/C3=CC=CN=C3",3.269,3,1,8]
["S2801","AZD4547","g11","L3800-12","in 10mM DMSO","N/A","N/A","Phase 2/3","FGFR","Angiogenesis","AZD4547 (ABSK 091) is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM in cell-free assays, weaker activity against FGFR4, VEGFR2(KDR), and little activity observed against IGFR, CDK2, and p38. Phase 2/3.",463.57,"1035270-39-3",{"v":92,"d":"92.00"},198.46,"<1","N/A","http://selleckchem.com/products/azd4547.html","C26H33N5O3","free base","ABSK 091","COC1=CC(=CC(=C1)OC)CCC2=CC(=N[NH]2)NC(=O)C3=CC=C(C=C3)N4CC(C)NC(C)C4",4.204,4,3,8]
["S2803","Galeterone","h11","L3800-12","in 10mM DMSO","N/A","N/A","Phase 3","Androgen Receptor,P450 (e.g. CYP17)","Endocrinology & Hormones","Galeterone (TOK-001) is a selective CYP17 inhibitor and androgen receptor (AR) antagonist with IC50 of 300 nM and 384 nM, respectively, and is a potent inhibitor of human prostate tumor growth. Phase 2.",388.55,"851983-85-2",{"v":24,"d":"24.00"},61.77,"<1","N/A","http://selleckchem.com/products/galeterone-tok-001.html","C26H32N2O","free base","TOK-001","CC12CCC(O)CC1=CCC3C2CCC4(C)C3CC=C4[N]5C=NC6=C5C=CC=C6",4.897,1,1,1]
["S2807","Dabrafenib (GSK2118436)","a2","L3800-13","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Raf","MAPK","Dabrafenib (GSK2118436, GSK2118436A) is a mutant BRAFV600E specific inhibitor with IC50 of 0.7 nM in cell-free assays, with 7- and 9-fold less potency against B-Raf(wt) and c-Raf, respectively.",519.56,"1195765-45-7",{"v":30,"d":"30.00"},57.74,"<1","N/A","http://selleckchem.com/products/dabrafenib-gsk2118436.html","C23H20F3N5O2S2","free base","GSK2118436A","CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(F)C(=CC=C3)N[S](=O)(=O)C4=C(F)C=CC=C4F",5.377,5,2,6]
["S2808","Ipatasertib (GDC-0068)","b2","L3800-13","in 10mM DMSO","N/A","N/A","Phase 3","Akt","PI3K/Akt/mTOR","Ipatasertib (GDC-0068, RG7440) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM in cell-free assays, 620-fold selectivity over PKA. Phase 2.",{"v":458,"d":"458.00"},"1001264-89-6",{"v":92,"d":"92.00"},200.87,"<1","N/A","http://selleckchem.com/products/gdc-0068.html","C24H32ClN5O2","free base","RG7440","CC(C)NCC(C(=O)N1CCN(CC1)C2=C3C(C)CC(O)C3=NC=N2)C4=CC=C(Cl)C=C4",3.102,3,2,6]
["S2809","MPEP","c2","L3800-13","in 10mM DMSO","DMF","N/A","N/A","GluR","Neuronal Signaling","MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.",193.24,"96206-92-7",{"v":39,"d":"39.00"},201.82,"<1","N/A","http://selleckchem.com/products/mpep.html","C14H11N","free base","N/A","CC1=NC(=CC=C1)C#CC2=CC=CC=C2",3.499,1,0,2]
["S2811","Sapanisertib (MLN0128)","d2","L3800-13","in 10mM DMSO","N/A","N/A","Phase 2","mTOR","PI3K/Akt/mTOR","Sapanisertib (MLN0128, INK 128, TAK-228) is a potent and selective mTOR inhibitor with IC50 of 1 nM in cell-free assays; >200-fold less potent to class I PI3K isoforms, superior in blocking mTORC1/2 and sensitive to pro-invasion genes (vs Rapamycin). Phase 1.",309.33,"1224844-38-5",{"v":62,"d":"62.00"},200.43,"<1","N/A","http://selleckchem.com/products/ink128.html","C15H15N7O","free base","INK 128,TAK-228","CC(C)[N]1N=C(C2=CC3=C(OC(=N3)N)C=C2)C4=C(N)N=CN=C14",1.886,5,2,2]
["S2812","(R)-(-)-Gossypol acetic acid","e2","L3800-13","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,Autophagy,Bcl-2","Apoptosis","(R)-(-)-Gossypol (AT-101) acetic acid, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM in cell-free assays; does not inhibit BIR3 domain and BID. AT-101 simultaneously triggers apoptosis and a cytoprotective type of autophagy. Phase 2.",578.61,"866541-93-7",{"v":116,"d":"116.00"},200.48,"<1","N/A","https://www.selleckchem.com/products/at101-acetic-acid.html","C30H30O8.C2H4O2","free base","AT-101 acetic acid, (-)-Gossypol acetic acid, (R)-Gossypol acetic acid","CC(C)C1=C(O)C(=C(C=O)C2=C1C=C(C)C(=C2O)C3=C(C)C=C4C(=C(O)C(=C(C=O)C4=C3O)O)C(C)C)O.CC(O)=O",6.388,3,6,5]
["S2814","Alpelisib (BYL719)","f2","L3800-13","in 10mM DMSO","FDA","N/A","Phase 3","PI3K","PI3K/Akt/mTOR","Alpelisib (BYL719) is a potent and selective PI3Kα inhibitor with IC50 of 5 nM in a cell-free assay, and minimal effect on PI3Kβ/γ/δ. Phase 2.",441.47,"1217486-61-7",{"v":88,"d":"88.00"},199.33,"<1","N/A","http://selleckchem.com/products/byl719.html","C19H22F3N5O2S","free base","N/A","CC1=C(SC(=N1)NC(=O)N2CCCC2C(N)=O)C3=CC(=NC=C3)C(C)(C)C(F)(F)F",2.826,4,2,5]
["S2818","Tacedinaline (CI994)","g2","L3800-13","in 10mM DMSO","N/A","N/A","Phase 3","HDAC","Epigenetics","Tacedinaline (CI994, PD-123654, GOE-5549, Acetyldinaline) is a selective class I HDAC inhibitor with IC50 of 0.9, 0.9, 1.2, and >20 μM for human HDAC 1, 2, 3, and 8, respectively. Phase 3.",{"v":269.3,"d":"269.30"},"112522-64-2",{"v":54,"d":"54.00"},200.52,"<1","N/A","http://selleckchem.com/products/ci994-tacedinaline.html","C15H15N3O2","free base","PD-123654, GOE-5549, Acetyldinaline","CC(=O)NC1=CC=C(C=C1)C(=O)NC2=C(N)C=CC=C2",0.988,2,3,3]
["S2822","OC000459","h2","L3800-13","in 10mM DMSO","N/A","N/A","Phase 3","GPR","Endocrinology & Hormones","OC000459 is a potent and selective D prostanoid receptor 2 (DP2) antagonist with IC50 of 13 nM. Phase 2.",348.37,"851723-84-7, 950688-14-9 (sodium salt)",{"v":4,"d":"4.00"},11.48,"<1","N/A","http://selleckchem.com/products/oc000459.html","C21H17FN2O2","free base","N/A","CC1=C(CC2=CC=C3C=CC=CC3=N2)C4=CC(=CC=C4[N]1CC(O)=O)F",4.329,2,0,4]
["S2823","Tideglusib (NP031112)","a3","L3800-13","in 10mM DMSO","N/A","N/A","Phase 2","COVID-19,GSK-3","PI3K/Akt/mTOR","Tideglusib (NP031112, NP-12) is an irreversible, non ATP-competitive GSK-3β inhibitor with IC50 of 60 nM in a cell-free assay; fails to inhibit kinases with a Cys homologous to Cys-199 located in the active site. Phase 2.",334.39,"865854-05-3",{"v":8,"d":"8.00"},23.92,"<1","N/A","http://selleckchem.com/products/tideglusib.html","C19H14N2O2S","free base","NP-12","O=C1SN(C(=O)N1CC2=CC=CC=C2)C3=C4C=CC=CC4=CC=C3",{"v":4.63,"d":"4.630"},2,0,3]
["S2830","Clindamycin","b3","L3800-13","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","USP42-NF37;BP2019;EP9.3;KP Ⅹ;Ph.Int_6th;JP17;Martindale:The Extra Pharmacopoeia","Marketed","Bacterial","Microbiology","Clindamycin inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.",424.98,"18323-44-9",{"v":85,"d":"85.00"},200.01,"<1","N/A","http://selleckchem.com/products/clindamycin.html","C18H33ClN2O5S","Free Base","N/A","CCCC1CC(N(C)C1)C(=O)NC(C(C)Cl)C2OC(SC)C(O)C(O)C2O",1.277,2,4,7]
["S2840","Apalutamide (ARN-509)","c3","L3800-13","in 10mM DMSO","FDA,EMA,NDC","N/A","Marketed","Androgen Receptor","Endocrinology & Hormones","Apalutamide (ARN-509) is a selective and competitive androgen receptor inhibitor with IC50 of 16 nM in a cell-free assay, useful for prostate cancer treatment. Phase 3.",477.43,"956104-40-8",{"v":18,"d":"18.00"},{"v":37.7,"d":"37.70"},"<1","N/A","http://selleckchem.com/products/arn-509.html","C21H15F4N5O2S","free base","N/A","CNC(=O)C1=CC=C(C=C1F)N2C(=S)N(C(=O)C23CCC3)C4=CN=C(C#N)C(=C4)C(F)(F)F",4.452,3,1,4]
["S2845","Semaxanib (SU5416)","d3","L3800-13","in 10mM DMSO","N/A","N/A","Phase 2","VEGFR","Protein Tyrosine Kinase","Semaxanib (SU5416, semaxinib) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR. Phase 3.",238.28,"204005-46-9",{"v":22,"d":"22.00"},92.33,"<1","N/A","http://selleckchem.com/products/semaxanib-su5416.html","C15H14N2O","free base","semaxinib","CC1=CC(=C([NH]1)/C=C/2C(=O)NC3=CC=CC=C23)C",2.747,1,2,1]
["S2851","Baricitinib (INCB028050)","e3","L3800-13","in 10mM DMSO","FDA,EMA,NDC,PMDA","N/A","Marketed","COVID-19,JAK","JAK/STAT","Baricitinib (LY3009104, INCB028050) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM in cell-free assays, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Baricitinib is found to reduce or interrupt the passage of the virus into target cells and is used in the treatment research for COVID-19. Phase 3.",371.42,"1187594-09-7",{"v":74,"d":"74.00"},199.24,"<1","N/A","http://selleckchem.com/products/baricitinib-ly3009104.html","C16H17N7O2S","free base","LY3009104","CC[S](=O)(=O)N1CC(CC#N)(C1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4",{"v":0.36,"d":"0.360"},5,1,5]
["S2853","Carfilzomib (PR-171)","f3","L3800-13","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Apoptosis related,Autophagy,COVID-19,Proteasome","Proteases","Carfilzomib (PR-171) is an irreversible proteasome inhibitor with IC50 of <5 nM in ANBL-6 cells, displayed preferential in vitro inhibitory potency against the ChT-L activity in the β5 subunit, but little or no effect on the PGPH and T-L activities. Carfilzomib activates prosurvival autophagy and induces cell apoptosis.",719.91,"868540-17-4",{"v":50,"d":"50.00"},69.45,"<1","N/A","http://selleckchem.com/products/carfilzomib-pr-171.html","C40H57N5O7","free base","N/A","CC(C)CC(NC(=O)C(CCC1=CC=CC=C1)NC(=O)CN2CCOCC2)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC(C)C)C(=O)C4(C)CO4",3.799,7,4,20]
["S2858","StemRegenin 1 (SR1)","g3","L3800-13","in 10mM DMSO","N/A","N/A","Phase 2","AhR","Metabolism","StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor with IC50 of 127 nM in a cell-free assay.",429.54,"1227633-49-9",{"v":86,"d":"86.00"},200.21,"<1","N/A","http://selleckchem.com/products/stemRegenin-1.html","C24H23N5OS","free base","N/A","CC(C)[N]1C=NC2=C1N=C(N=C2NCCC3=CC=C(O)C=C3)C4=CSC5=CC=CC=C45",{"v":5.19,"d":"5.190"},3,2,6]
["S2859","Golvatinib (E7050)","h3","L3800-13","in 10mM DMSO","N/A","N/A","Phase 2","c-Met,VEGFR","Protein Tyrosine Kinase","Golvatinib (E7050) is a dual c-Met and VEGFR-2 inhibitor with IC50 of 14 nM and 16 nM, does not inhibit bFGF-stimulated HUVEC growth (up to 1000 nM). Phase 1/2.",633.69,"928037-13-2",{"v":20,"d":"20.00"},31.56,"<1","N/A","http://selleckchem.com/products/golvatinib-e7050.html","C33H37F2N7O4","free base","N/A","CN1CCN(CC1)C2CCN(CC2)C(=O)NC3=NC=CC(=C3)OC4=CC(=C(NC(=O)C5(CC5)C(=O)NC6=CC=C(F)C=C6)C=C4)F",3.173,5,3,8]
["S2864","IMD 0354","a4","L3800-13","in 10mM DMSO","N/A","N/A","Phase 1","IκB/IKK","NF-κB","IMD-0354 (IKK2 Inhibitor V) is an IKKβ inhibitor and blocks IκBα phosphorylation in NF-κB pathway.",383.67,"978-62-1",{"v":10,"d":"10.00"},26.06,"<1","N/A","http://selleckchem.com/products/imd-0354.html","C15H8ClF6NO2","free base","IKK2 Inhibitor V","OC1=C(C=C(Cl)C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F",4.921,1,2,4]
["S2866","U-104","b4","L3800-13","in 10mM DMSO","N/A","N/A","Phase 2","Carbonic Anhydrase","Metabolism","U-104 (MST-104, NSC 213841, SLC-0111, WBI-5111) is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II.",309.32,"178606-66-1",{"v":62,"d":"62.00"},200.44,"<1","N/A","http://selleckchem.com/products/u-104.html","C13H12FN3O3S","free base","MST-104, NSC 213841, SLC-0111, WBI-5111","N[S](=O)(=O)C1=CC=C(NC(=O)NC2=CC=C(F)C=C2)C=C1",1.433,3,3,3]
["S2868","Alogliptin (SYR-322) benzoate","c4","L3800-13","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","DPP","Proteases","Alogliptin (SYR-322) benzoate is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.",461.51,"850649-62-6",{"v":68,"d":"68.00"},147.34,{"v":2,"d":"2.00"},4.33,"http://selleckchem.com/products/alogliptin-syr-322.html","C18H21N5O2.C7H6O2","benzoate","SYR-322","CN1C(=O)C=C(N2CCCC(N)C2)N(CC3=CC=CC=C3C#N)C1=O",1.271,2,1,3]
["S2872","GW5074","d4","L3800-13","in 10mM DMSO","N/A","N/A","Phase 1/2","Apoptosis related,Raf","MAPK","GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM, no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms is noted. GW5074 inhibits LK-induced apoptosis.",520.94,"220904-83-6",{"v":104,"d":"104.00"},199.64,"<1","N/A","http://selleckchem.com/products/gw5074.html","C15H8Br2INO2","free base","N/A","OC1=C(Br)C=C(C=C1Br)C=C2C(=O)NC3=CC=C(I)C=C23",4.564,1,2,1]
["S2874","Camostat Mesilate","e4","L3800-13","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,JP17","N/A","COVID-19,Sodium Channel","Transmembrane Transporters","Camostat (FOY-305, FOY-S980) is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.",494.52,"59721-29-8",{"v":99,"d":"99.00"},200.19,{"v":10,"d":"10.00"},20.22,"http://selleckchem.com/products/camostat-mesilate-foy-305.html","C20H22N4O5.CH4O3S","Mesilate","FOY-305, FOY-S980","CN(C)C(=O)COC(=O)CC1=CC=C(OC(=O)C2=CC=C(NC(N)=N)C=C2)C=C1.C[S](O)(=O)=O",0.969,5,2,10]
["S2875","Prucalopride","f4","L3800-13","in 10mM DMSO","FDA,EMA,HMA,CFDA,NDC","N/A","Marketed","5-HT Receptor","Neuronal Signaling","Prucalopride (R-93877) is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively, exhibits >290-fold selectivity against other 5-HT receptor subtypes.",367.87,"179474-81-8",{"v":60,"d":"60.00"},{"v":163.1,"d":"163.10"},"<1","N/A","http://selleckchem.com/products/prucalopride.html","C18H26ClN3O3","Free Base","R-93877","COCCCN1CCC(CC1)NC(=O)C2=CC(=C(N)C3=C2OCC3)Cl",1.056,3,2,6]
["S2883","4-Aminohippuric Acid","g4","L3800-13","in 10mM DMSO","N/A","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,BP2017","N/A","Others","Others","4-Aminohippuric acid is a typical substrate of organic anion transport systems.",194.19,"61-78-9",{"v":39,"d":"39.00"},200.83,{"v":3,"d":"3.00"},15.45,"http://selleckchem.com/products/4-aminohippuric-acid.html","C9H10N2O3","free base","N/A","NC1=CC=C(C=C1)C(=O)NCC(O)=O",-0.227,2,2,3]
["S2884","Acesulfame Potassium","h4","L3800-13","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","Phase 2","Others","Others","Acesulfame potassium is a non-nutritive sweetener.",202.25,"55589-62-3",{"v":40,"d":"40.00"},197.78,{"v":40,"d":"40.00"},197.78,"http://selleckchem.com/products/acesulfame-potassium.html","C4H5NO4S.K","Potassium Salt","N/A","[KH].CC1=CC(=O)N[S](=O)(=O)O1",-0.858,2,1,0]
["S2890","PF-562271","a5","L3800-13","in 10mM DMSO","N/A","N/A","Phase 1","CDK,FAK,Pyk2","Angiogenesis","PF-562271 (PF-00562271) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.",507.49,"717907-75-0",{"v":100,"d":"100.00"},197.05,"<1","N/A","http://selleckchem.com/products/pf-562271.html","C21H20F3N7O3S","free base","PF-00562271","CN(C1=C(CNC2=C(C=NC(=N2)NC3=CC=C4NC(=O)CC4=C3)C(F)(F)F)C=CC=N1)[S](C)(=O)=O",2.491,6,3,8]
["S2894","SB742457","b5","L3800-13","in 10mM DMSO","N/A","N/A","Phase 3","5-HT Receptor","Neuronal Signaling","SB742457 (GSK 742457) is a highly selective 5-HT6 receptor antagonist with pKi of 9.63, exhibits >100-fold selectivity over other receptors. Phase 2.",353.44,"607742-69-8",{"v":78,"d":"78.00"},220.69,"<1","N/A","http://selleckchem.com/products/sb-742457.html","C19H19N3O2S","free base","GSK 742457","O=[S](=O)(C1=CC=CC=C1)C2=CC3=C(N=C2)C(=CC=C3)N4CCNCC4",2.702,3,1,3]
["S2900","Cobicistat (GS-9350)","c5","L3800-13","in 10mM DMSO","FDA,DMF,EMA,NDC","N/A","Marketed","P450 (e.g. CYP17)","Metabolism","Cobicistat (GS-9350) is a potent and selective inhibitor of CYP3A with IC50 of 30-285 nM.",776.02,"1004316-88-4",{"v":100,"d":"100.00"},128.86,"<1","N/A","http://selleckchem.com/products/cobicistat-gs-9350.html","C40H53N7O5S2","free base","N/A","CC(C)C1=NC(=CS1)CN(C)C(=O)NC(CCN2CCOCC2)C(=O)NC(CCC(CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)CC5=CC=CC=C5",4.765,7,3,20]
["S2902","S-Ruxolitinib (INCB018424)","d5","L3800-13","in 10mM DMSO","FDA","N/A","Marketed","JAK","JAK/STAT","S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Phase 3.",306.37,"941685-37-6",{"v":61,"d":"61.00"},199.11,{"v":5,"d":"5.00"},16.32,"http://selleckchem.com/products/s-ruxolitinib.html","C17H18N6","free base","N/A","N#CCC(C1CCCC1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4",{"v":2.88,"d":"2.880"},3,1,4]
["S2903","Lumiracoxib","e5","L3800-13","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","Marketed","COX","Neuronal Signaling","Lumiracoxib (COX-189) is a novel, selective COX-2 inhibitor with Ki of  0.06 μM. It also inhibits COX1 with Ki of 3 μM.",293.72,"220991-20-8",{"v":59,"d":"59.00"},200.87,"<1","N/A","http://selleckchem.com/products/lumiracoxib-cox-189.html","C15H13ClFNO2","free base","COX-189","CC1=CC=C(NC2=C(Cl)C=CC=C2F)C(=C1)CC(O)=O",{"v":4.4,"d":"4.400"},1,1,4]
["S2904","PF-477736","f5","L3800-13","in 10mM DMSO","N/A","N/A","Phase 1","Chk","Cell Cycle","PF-477736 (PF-736, PF-00477736) is a selective, potent and ATP-competitive Chk1 inhibitor with Ki of 0.49 nM in a cell-free assay and also inhibits VEGFR2, Aurora-A, FGFR3, Flt3, Fms (CSF1R), Ret and Yes. It shows ~100-fold selectivity for Chk1 than Chk2.",419.48,"952021-60-2",{"v":6,"d":"6.00"},{"v":14.3,"d":"14.30"},"<1","N/A","http://selleckchem.com/products/pf-477736.html","C22H25N7O2","free base","PF-736, PF-00477736","C[N]1C=C(C=N1)C2=C3C=NNC(=O)C4=C3C(=CC(=C4)NC(=O)C(N)C5CCCCC5)[NH]2",2.089,4,4,4]
["S2907","Pirfenidone (S-7701)","g5","L3800-13","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2016","Marketed","CCR,TGF-beta/Smad","TGF-beta/Smad","Pirfenidone (S-7701, AMR-69) is an inhibitor for TGF-β production and TGF-β stimulated collagen production, reduces production of TNF-α and IL-1β, and also has anti-fibrotic and anti-inflammatory properties. Pirfenidone attenuates chemokine (CC motif) ligand-2 (CCL2) and CCL12 production with anti-fibrotic activity. Phase 3.",185.22,"53179-13-8",{"v":37,"d":"37.00"},199.76,"<1","N/A","http://selleckchem.com/products/pirfenidone.html","C12H11NO","free base","AMR-69","CC1=CN(C(=O)C=C1)C2=CC=CC=C2",1.905,1,0,1]
["S2910","Tempol","h5","L3800-13","in 10mM DMSO","N/A","N/A","Phase 3","Immunology & Inflammation related","Immunology & Inflammation","Tempol (4-Hydroxy-TEMPO) is a superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects. Phase 2.",172.24,"2226-96-2",{"v":34,"d":"34.00"},{"v":197.4,"d":"197.40"},{"v":34,"d":"34.00"},{"v":197.4,"d":"197.40"},"http://selleckchem.com/products/tempol-4-hydroxy-tempo.html","C9H18NO2","free base","4-Hydroxy-TEMPO","CC1(C)CC(O)CC(C)(C)N1[O]",0.413,0,1,0]
["S2914","Dapivirine (TMC120)","a6","L3800-13","in 10mM DMSO","N/A","N/A","Phase 3","Reverse Transcriptase","Microbiology","Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM, inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates. Phase 3.",{"v":329.4,"d":"329.40"},"244767-67-7",{"v":34,"d":"34.00"},103.22,"<1","N/A","http://selleckchem.com/products/dapivirine.html","C20H19N5","free base","N/A","CC1=CC(=C(NC2=CC=NC(=N2)NC3=CC=C(C=C3)C#N)C(=C1)C)C",5.549,2,2,4]
["S2922","Icotinib (BPI-2009H)","b6","L3800-13","in 10mM DMSO","CFDA","N/A","Marketed","EGFR","Protein Tyrosine Kinase","Icotinib (BPI-2009H) is a potent and specific EGFR inhibitor with IC50 of 5 nM, including the EGFR, EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R).",391.42,"610798-31-7",{"v":78,"d":"78.00"},199.27,"<1","N/A","http://selleckchem.com/products/icotinib.html","C22H21N3O4","free base","BPI-2009H","C#CC1=CC(=CC=C1)NC2=NC=NC3=C2C=C4OCCOCCOCCOC4=C3",4.128,6,1,2]
["S2925","Evacetrapib (LY2484595)","c6","L3800-13","in 10mM DMSO","N/A","N/A","Phase 3","CETP","Metabolism","Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.",638.65,"1186486-62-3",{"v":12.8,"d":"12.80"},20.04,"<1","N/A","http://selleckchem.com/products/evacetrapib-ly2484595.html","C31H36F6N6O2","free base","N/A","C[N]1N=NC(=N1)N(CC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)C3CCCN(CC4CCC(CC4)C(O)=O)C5=C3C=C(C)C=C5C",8.617,4,0,9]
["S2928","TAK-715","d6","L3800-13","in 10mM DMSO","N/A","N/A","Phase 2","p38 MAPK","MAPK","TAK-715 is a p38 MAPK inhibitor for p38α with IC50 of 7.1 nM, 28-fold more selective for p38α over p38β, no inhibition to p38γ/δ, JNK1, ERK1, IKKβ, MEKK1 or TAK1. Phase 2.",399.51,"303162-79-0",{"v":80,"d":"80.00"},200.25,"<1","N/A","http://selleckchem.com/products/tak-715.html","C24H21N3OS","free base","N/A","CCC1=NC(=C(S1)C2=CC(=NC=C2)NC(=O)C3=CC=CC=C3)C4=CC=CC(=C4)C",5.629,3,1,5]
["S3000","Carbazochrome sodium sulfonate (AC-17)","e6","L3800-13","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17","N/A","Others","Others","Carbazochrome sodium sulfonate (AC-17) is an antihemorrhagic for use in the treatment of hemorrhoids.",322.27,"51460-26-5",{"v":64,"d":"64.00"},198.59,{"v":3,"d":"3.00"},9.31,"http://selleckchem.com/products/carbazochrome-sodium-sulfonate.html","C10H11N4NaO5S","Sodium","N/A","[Na+].CN1C(CC2=C\\C(=N\\NC(N)=O)C(=O)C=C12)[S]([O-])(=O)=O",-3.186,3,2,2]
["S3001","Clevudine","f6","L3800-13","in 10mM DMSO","marketed in Korea","N/A","Marketed","DNA/RNA Synthesis","DNA Damage/DNA Repair","Clevudine(Levovir,L-FMAU) is an antiviral drug for the treatment of hepatitis B.",260.22,"163252-36-6",{"v":52,"d":"52.00"},199.83,{"v":52,"d":"52.00"},199.83,"http://selleckchem.com/products/clevudine-levovir.html","C10H13FN2O5","free base","Levovir,L-FMAU","CC1=CN(C2OC(CO)C(O)C2F)C(=O)NC1=O",-1.065,3,3,2]
["S3002","Rivaroxaban (BAY 59-7939)","g6","L3800-13","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Factor Xa","Metabolism","Rivaroxaban (BAY 59-7939) is a direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0.7 nM in cell-free assays, respectively. It is selective for human factor Xa, for which it has >10 000-fold greater selectivity than for other biologically relevant serine proteases (IC50 >20 μM).",435.88,"366789-02-8",{"v":87,"d":"87.00"},{"v":199.6,"d":"199.60"},"<1","N/A","http://selleckchem.com/products/Rivaroxaban.html","C19H18ClN3O5S","free base","BAY 59-7939","ClC1=CC=C(S1)C(=O)NCC2CN(C(=O)O2)C3=CC=C(C=C3)N4CCOCC4=O",1.797,5,1,5]
["S3003","Prostaglandin E2 (PGE2)","h6","L3800-13","in 10mM DMSO","DMF,CFDA","N/A","Marketed","PGES,Prostaglandin Receptor","Endocrinology & Hormones","Prostaglandin E2 (PGE2, Dinoprostone,Prepidil) plays important effects in labour (softens cervix and causes uterine contraction) and also stimulates osteoblasts to release factors that stimulate bone resorption by osteoclasts.",352.47,"363-24-6",{"v":70,"d":"70.00"},{"v":198.6,"d":"198.60"},{"v":40,"d":"40.00"},113.49,"http://selleckchem.com/products/prostaglandin-e2-cervidil.html","C20H32O5","free base","Dinoprostone,Prepidil","CCCCCC(O)/C=C/C1C(O)CC(=O)C1C\\C=C/CCCC(O)=O",3.199,2,2,12]
["S3005","Paroxetine HCl","a7","L3800-13","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","Marketed","Serotonin Transporter","Neuronal Signaling","Paroxetine HCl (BRL-29060A, FG-7051) is an antidepressant drug of the SSRI type.",365.83,"78246-49-8",{"v":73,"d":"73.00"},199.55,{"v":1,"d":"1.00"},2.73,"http://selleckchem.com/products/paroxetine-hcl.html","C19H20FNO3.HCl","Hydrochloride","BRL-29060A, FG-7051","Cl.FC1=CC=C(C=C1)C2CCNCC2COC3=CC4=C(OCO4)C=C3",3.611,3,1,4]
["S3008","Zaltoprofen","b7","L3800-13","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17","Marketed","COX","Neuronal Signaling","Zaltoprofen(CN100,Soleton) is an inhibitor of COX-1 and COX-2 for treatment of arthritis.",298.36,"74711-43-6",{"v":60,"d":"60.00"},{"v":201.1,"d":"201.10"},"<1","N/A","http://selleckchem.com/products/zaltoprofen.html","C17H14O3S","free base","CN100,Soleton","CC(C(O)=O)C1=CC2=C(SC3=CC=CC=C3C(=O)C2)C=C1",3.684,2,0,2]
["S3015","Amoxicillin","d7","L3800-13","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,EP9.1,JP17,BP2017,Ph.Int_6th,USP36-NF31,IP2010","Marketed","Antibiotics,Bacterial","Microbiology","Amoxicillin (Amoxycillin) is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms.",{"v":365.4,"d":"365.40"},"26787-78-0",{"v":73,"d":"73.00"},199.78,"<1","N/A","http://selleckchem.com/products/amoxicillin-amoxycillin.html","C16H19N3O5S","Free Base","Amoxycillin","CC1(C)SC2C(NC(=O)C(N)C3=CC=C(O)C=C3)C(=O)N2C1C(O)=O",-2.539,3,3,4]
["S3018","Niflumic acid","f7","L3800-13","in 10mM DMSO","N/A","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","COX,GABA Receptor","Neuronal Signaling","Niflumic acid(Nifluril) is an inhibitor of cyclooxygenase-2 used for joint and muscular pain.",282.22,"4394-00-7",{"v":56,"d":"56.00"},198.43,"<1","N/A","http://selleckchem.com/products/niflumic-acid.html","C13H9F3N2O2","free base","Nifluril","OC(=O)C1=CC=CN=C1NC2=CC=CC(=C2)C(F)(F)F",{"v":3.34,"d":"3.340"},2,1,4]
["S3022","Cabazitaxel (XRP6258)","a8","L3800-13","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Registered","Autophagy,Microtubule Associated","Cytoskeletal Signaling","Cabazitaxel (RPR-116258A, XRP6258, TXD 258, Taxoid XRP6258) is a semi-synthetic derivative of a natural taxoid that kills cancer cells by inhibiting cell division and growth. Cabazitaxel exerts its effects by inhibiting microtubule growth and assembly, processes that are essential for cells to divide. Cabazitaxel induces autophagy via the PI3K/Akt/mTOR pathway.",835.93,"183133-96-2",{"v":100,"d":"100.00"},119.63,"<1","N/A","http://selleckchem.com/products/cabazitaxel-jevtana.html","C45H57NO14","free base","RPR-116258A, TXD 258, Taxoid XRP6258","COC1CC2OCC2(OC(C)=O)C3C(OC(=O)C4=CC=CC=C4)C5(O)CC(OC(=O)C(O)C(NC(=O)OC(C)(C)C)C6=CC=CC=C6)C(=C(C(OC)C(=O)C13C)C5(C)C)C",3.403,12,2,15]
["S3027","Fenoprofen calcium hydrate","e8","L3800-13","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017","N/A","Immunology & Inflammation related","Immunology & Inflammation","Fenoprofen calcium hydrate(Fenoprofen calcium salt dihydrate,Feprona dihydrate,Progesic dihydrate) is a non-steroidal anti-inflammatory drug (NSAID).",558.63,"71720-56-4, 53746-45-5",{"v":48,"d":"48.00"},85.92,"<1","N/A","http://selleckchem.com/products/fenoprofen-calcium-hydrate.html","C30H30CaO8","Calcium dihydrate salt","Fenoprofen calcium salt dihydrate,Feprona dihydrate,Progesic dihydrate","O.O.CC(C(=O)O[Ca]OC(=O)C(C)C1=CC=CC(=C1)OC2=CC=CC=C2)C3=CC=CC(=C3)OC4=CC=CC=C4",6.802,6,0,12]
["S3032","Bindarit (AF 2838)","h8","L3800-13","in 10mM DMSO","N/A","N/A","Phase 3","CCR,Immunology & Inflammation related","Immunology & Inflammation","Bindarit (AF 2838) exhibits selective inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.",324.37,"130641-38-2",{"v":64,"d":"64.00"},197.31,"<1","N/A","http://selleckchem.com/products/bindarit.html","C19H20N2O3","free base","AF 2838","CC(C)(OCC1=N[N](CC2=CC=CC=C2)C3=C1C=CC=C3)C(O)=O",3.559,3,0,6]
["S3036","Pravastatin sodium","c9","L3800-13","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,USP39-NF34,EP9.1,JP17,BP2017,IP2010","Marketed","HMG-CoA Reductase","Metabolism","Pravastatin sodium (CS-514) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.",446.51,"81131-70-6",{"v":89,"d":"89.00"},199.32,{"v":89,"d":"89.00"},199.32,"http://selleckchem.com/products/pravastatin-pravachol.html","C23H35O7.Na","sodium","CS-514 Sodium","[Na+].CCC(C)C(=O)OC1CC(O)C=C2C=CC(C)C(CCC(O)CC(O)CC([O-])=O)C12",0.682,2,3,11]
["S3037","Bepotastine Besilate","d9","L3800-13","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,JP17","Marketed","COVID-19,Histamine Receptor","Neuronal Signaling","Bepotastine Besilate (TAU 284) is a non-sedating, selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7.",547.06,"190786-44-8",{"v":109,"d":"109.00"},199.25,"<1","N/A","http://selleckchem.com/products/bepotastine-besilate.html","C21H25ClN2O3.C6H6O3S","Besilate salt","TAU 284","OC(=O)CCCN1CCC(CC1)OC(C2=CC=C(Cl)C=C2)C3=NC=CC=C3.O[S](=O)(=O)C4=CC=CC=C4",1.371,3,0,9]
["S3045","Cinepazide maleate","g9","L3800-13","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","Marketed","Calcium Channel","Transmembrane Transporters","Cinepazide maleate is a maleate salt form of cinepazide which is a vasodilator.",533.57,"26328-04-1",{"v":107,"d":"107.00"},200.54,{"v":107,"d":"107.00"},200.54,"http://selleckchem.com/products/cinepazide-maleate.html","C22H31N3O5.C4H4O4","Maleate","N/A","COC1=C(OC)C(=CC(=C1)/C=C/C(=O)N2CCN(CC2)CC(=O)N3CCCC3)OC.OC(=O)\\C=C/C(O)=O",{"v":-1.65,"d":"-1.650"},7,0,9]
["S3052","Rupatadine Fumarate","c10","L3800-13","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.3","Marketed","Histamine Receptor","Neuronal Signaling","Rupatadine is an inhibitor of PAFR and histamine (H1) receptor with Ki of 550 nM and 102 nM, respectively.",532.03,"182349-12-8",{"v":9,"d":"9.00"},16.92,"<1","N/A","http://selleckchem.com/products/rupatadine-fumarate.html","C26H26ClN3.C4H4O4","Fumarate","N/A","CC1=CN=CC(=C1)CN2CCC(CC2)=C3C4=CC=C(Cl)C=C4CCC5=CC=CN=C35.OC(=O)\\C=C\\C(O)=O",2.672,4,0,4]
["S3057","Azilsartan Medoxomil","f10","L3800-13","in 10mM DMSO","DMF,EMA,HMA","N/A","Marketed","Angiotensin Receptor","GPCR & G Protein","Azilsartan Medoxomil (TAK-491) is a potent angiotensin II type 1 (AT1) receptor antagonist, inhibits the RAAS, with an IC50 of 2.6 nM, exhibits >10,000-fold selectivity over AT2.",568.53,"863031-21-4",{"v":114,"d":"114.00"},200.52,"<1","N/A","http://selleckchem.com/products/azilsartan-medoxomil-tak-491.html","C30H24N4O8","free base","TAK-491","CCOC1=NC2=CC=CC(=C2[N]1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)ON5)C(=O)OCC6=C(C)OC(=O)O6",{"v":5.27,"d":"5.270"},10,1,10]
["S3062","Diclofenac Potassium","a11","L3800-13","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","Marketed","Immunology & Inflammation related","Immunology & Inflammation","Diclofenac potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.",334.24,"15307-81-0",{"v":69,"d":"69.00"},206.44,{"v":10,"d":"10.00"},29.92,"http://selleckchem.com/products/diclofenac-potassium.html","C14H10Cl2KNO2","Potassium","CGP-45840B","[K+].[O-]C(=O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl",2.899,0,1,4]
["S3070","Piracetam","e11","L3800-13","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,KP Ⅹ,EP9.2,BP2017","Registered","GluR","Neuronal Signaling","Piracetam (UCB 6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders.",142.16,"7491-74-9",{"v":72,"d":"72.00"},506.47,{"v":72,"d":"72.00"},506.47,"http://selleckchem.com/products/piracetam.html","C6H10N2O2","free base","UCB 6215","NC(=O)CN1CCCC1=O",-1.312,2,1,2]
["S3077","Tazobactam","h11","L3800-13","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,JP17","Marketed","Selection Antibiotics for Transfected Cell,β-lactamase","Microbiology","Tazobactam (Tazobactam acid, Tazobactamum) is a β-lactamases Inhibitor with antibacterial activity. It also inhibits the class D oxacillinase OXA-2. It is used in combination with piperacillin and other β-lactam antibiotics to broaden their spectrum and enhance their effect.",300.29,"89786-04-9",{"v":60,"d":"60.00"},199.81,"<1","N/A","http://selleckchem.com/products/tazobactam.html","C10H12N4O5S","free base","Tazobactam acid, Tazobactamum","CC1(C[N]2C=CN=N2)C(N3C(CC3=O)[S]1(=O)=O)C(O)=O",-1.189,6,0,3]
["S3080","Etravirine (TMC125)","c2","L3800-14","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Reverse Transcriptase","Microbiology","Etravirine (TMC125, R-165335) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.",435.28,"269055-15-4",{"v":42,"d":"42.00"},96.49,"<1","N/A","http://selleckchem.com/products/etravirine-tmc125.html","C20H15BrN6O","free base","R-165335","CC1=CC(=CC(=C1OC2=C(Br)C(=NC(=N2)NC3=CC=C(C=C3)C#N)N)C)C#N",5.492,3,2,4]
["S3081","Ulipristal Acetate (CDB 2914)","d2","L3800-14","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC","N/A","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Ulipristal acetate (CDB-2914, HRP 2000, RU 44675) is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.",475.62,"126784-99-4",{"v":83,"d":"83.00"},191.43,"<1","N/A","http://selleckchem.com/products/ulipristal.html","C30H37NO4","free base","HRP 2000, RU 44675","CN(C)C1=CC=C(C=C1)C2CC3(C)C(CCC3(OC(C)=O)C(C)=O)C4CCC5=CC(=O)CCC5=C24",4.309,2,0,3]
["S3104","Moguisteine","g2","L3800-14","in 10mM DMSO","marketed in Italy","N/A","N/A","Others","Others","Moguisteine(BBR-2173) is a novel peripheral non-narcotic antitussive drug.",339.41,"119637-67-1",{"v":68,"d":"68.00"},200.35,"<1","N/A","http://selleckchem.com/products/moguisteine.html","C16H21NO5S","free base","BBR-2173","CCOC(=O)CC(=O)N1CCSC1COC2=CC=CC=C2OC",2.212,5,0,8]
["S3114","Vitamin C","c3","L3800-14","in 10mM DMSO","DMF,CFDA,NDC,HMA","USP32-NF27","N/A","Vitamin","Metabolism","Vitamin C (L-Ascorbic acid) is a water-soluble vitamin indicated for the prevention and treatment of scurvy.",176.12,"50-81-7",{"v":35,"d":"35.00"},198.73,{"v":35,"d":"35.00"},198.73,"http://selleckchem.com/products/vitamin-c-ascorbic-acid.html","C6H8O6","free base","L-Ascorbic acid","OCC(O)C1OC(=O)C(=C1O)O",-1.709,2,4,2]
["S3120","Doxepin HCl","f3","L3800-14","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","Marketed","Histamine Receptor","Neuronal Signaling","Doxepin is a tricyclic antidepressant formulated as a mixture of E-(trans) and Z-(cis) stereoisomers. It inhibits CYP2D6 activity in vivo.",315.84,"1229-29-4",{"v":63,"d":"63.00"},199.47,{"v":63,"d":"63.00"},199.47,"http://selleckchem.com/products/doxepin-hydrochloride-sinequan.html","C19H21NO.HCl","hydrochloride","N/A","Cl.CN(C)CC\\C=C1/C2=CC=CC=C2COC3=C1C=CC=C3",{"v":4.29,"d":"4.290"},1,0,3]
["S3129","Trimethoprim","a4","L3800-14","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,EP9.1,Ph.Int_6th,BP2017,IP2010","Marketed","Antibiotics,Bacterial,DHFR","Microbiology","Trimethoprim (BW 56-72, NIH 204, NSC-106568) is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.",290.32,"738-70-5",{"v":58,"d":"58.00"},199.78,"<1","N/A","http://selleckchem.com/products/trimethoprim.html","C14H18N4O3","free base","BW 56-72, NIH 204, NSC-106568","COC1=C(OC)C(=CC(=C1)CC2=CN=C(N)N=C2N)OC",1.543,5,2,5]
["S3137","Sodium salicylate","e4","L3800-14","in 10mM DMSO","DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","Phase 3","NF-κB","NF-κB","Sodium salicylate(2-Hydroxybenzoic acid Sodium salt,Salicylic acid Sodium salt) is used in medicine as an analgesic and antipyretic.",161.11,"54-21-7",{"v":32,"d":"32.00"},198.62,{"v":32,"d":"32.00"},198.62,"http://selleckchem.com/products/sodium-salicylate.html","C7H6O3.Na","sodium salt","2-Hydroxybenzoic acid Sodium salt,Salicylic acid Sodium salt","[NaH].OC(=O)C1=CC=CC=C1O",1.217,1,1,1]
["S3140","Milnacipran HCl","g4","L3800-14","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Serotonin Transporter","Neuronal Signaling","Milnacipran inhibits both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively.",282.81,"101152-94-7",{"v":57,"d":"57.00"},201.55,{"v":57,"d":"57.00"},201.55,"http://selleckchem.com/products/milnacipran-hydrochloride.html","C15H22N2O.HCl","HCl","N/A","Cl.CCN(CC)C(=O)C1(CC1CN)C2=CC=CC=C2",{"v":1.67,"d":"1.670"},1,1,5]
["S3144","Darifenacin HBr","h4","L3800-14","in 10mM DMSO","FDA,DMF,EMA,NDC","Martindale:The Extra Pharmacopoeia","Marketed","AChR","Neuronal Signaling","Darifenacin HBr (UK-88525) is a selective M3 muscarinic receptor antagonist with pKi of 8.9.",507.46,"133099-07-7",{"v":100,"d":"100.00"},197.06,"<1","N/A","http://selleckchem.com/products/darifenacin-hydrobromide.html","C28H30N2O2.HBr","HBr","UK-88525","Br.NC(=O)C(C1CCN(CCC2=CC=C3OCCC3=C2)C1)(C4=CC=CC=C4)C5=CC=CC=C5",5.048,2,1,7]
["S3150","Articaine HCl","c5","L3800-14","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","Phase 4","NF-κB","Immunology & Inflammation","Articaine (Ultracaine) is a dental local anesthetic which contains an additional ester group that is metabolized by estearases in blood and tissue.",320.84,"23964-57-0",{"v":64,"d":"64.00"},199.48,{"v":64,"d":"64.00"},199.48,"http://selleckchem.com/products/articaine-hydrochloride.html","C13H20N2O3S.HCl","Hydrochloride","Ultracaine","Cl.CCCNC(C)C(=O)NC1=C(SC=C1C)C(=O)OC",2.454,3,2,7]
["S3154","Butenafine HCl","f5","L3800-14","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,JP17","Marketed","Fungal","Microbiology","Butenafine HCl (KP-363) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.",353.93,"101827-46-7",{"v":70,"d":"70.00"},197.78,"<1","N/A","http://selleckchem.com/products/butenafine-hydrochloride.html","C23H27N.HCl","HCl","KP-363","Cl.CN(CC1=CC=C(C=C1)C(C)(C)C)CC2=C3C=CC=CC3=CC=C2",6.177,0,0,5]
["S3162","Tylosin tartrate","b6","L3800-14","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017,IP2010","N/A","Antibiotics,Antibiotics for Mammalian Cell Culture","Microbiology","Tylosin tartrate is a macrolide antibiotic approved for the control of mycoplasmosis in poultry.",1066.19,"74610-55-2",{"v":300,"d":"300.00"},281.38,{"v":200,"d":"200.00"},187.58,"http://selleckchem.com/products/tylosin-tartrate.html","C46H77NO17.C4H6O6","Tartrate","N/A","CCC1OC(=O)CC(O)C(C)C(OC2OC(C)C(OC3CC(C)(O)C(O)C(C)O3)C(C2O)N(C)C)C(CC=O)CC(C)C(=O)\\C=C\\C(=C\\C1COC4OC(C)C(O)C(OC)C4OC)C.OC(C(O)C(O)=O)C(O)=O",-2.989,14,6,16]
["S3170","Ampicillin sodium","e6","L3800-14","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,KP Ⅹ,EP9.1,JP17,BP2017,Ph.Int_5th,USP39-NF34,IP2010","Phase 3","Antibiotics,Antibiotics for Mammalian Cell Culture,Selection Antibiotics for Transfected Cell","Microbiology","Ampicillin(D-(-)-α-Aminobenzylpenicillin sodium salt) is a beta-lactam antibiotic that is part of the aminopenicillin family.",371.39,"69-52-3",{"v":37,"d":"37.00"},99.63,{"v":74,"d":"74.00"},199.25,"http://selleckchem.com/products/ampicillin-sodium.html","C16H18N3NaO4S","Sodium","D-(-)-α-Aminobenzylpenicillin sodium salt","[Na+].CC1(C)SC2C(NC(=O)C(N)C3=CC=CC=C3)C(=O)N2C1C([O-])=O",-1.292,2,2,4]
["S3175","Atomoxetine HCl","h6","L3800-14","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","Marketed","5-HT Receptor","Neuronal Signaling","Atomoxetine (LY 139603) is a selective norepinephrine (NE) transporter inhibitor with Ki of 5 nM, with 15- and 290-fold lower affinity for human 5-HT and DA transporters.",291.82,"82248-59-7",{"v":58,"d":"58.00"},198.75,{"v":2,"d":"2.00"},6.85,"http://selleckchem.com/products/atomoxetine-hydrochloride.html","C17H21NO.HCl","HCl","LY 139603 HCl","Cl.CNCCC(OC1=CC=CC=C1C)C2=CC=CC=C2",3.959,1,1,6]
["S3180","Eletriptan HBr","d7","L3800-14","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor","Neuronal Signaling","Eletriptan (UK-116044) is a selective 5-HT1B and 5-HT1D receptor agonist with Ki of 0.92 nM and 3.14 nM, respectively.",463.43,"177834-92-3",{"v":93,"d":"93.00"},200.68,"<1","N/A","http://selleckchem.com/products/eletriptan-hydrobromide.html","C22H26N2O2S.HBr","HBr","UK-116044","Br.CN1CCCC1CC2=C[NH]C3=C2C=C(CC[S](=O)(=O)C4=CC=CC=C4)C=C3",4.929,2,1,6]
["S3185","Adrenalone HCl","g7","L3800-14","in 10mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017","N/A","Adrenergic Receptor","Neuronal Signaling","Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic, mainly acts on alpha-1 adrenergic receptors.",217.65,"62-13-5",{"v":44,"d":"44.00"},202.16,{"v":44,"d":"44.00"},202.16,"http://selleckchem.com/products/adrenalone-hcl.html","C9H11NO3.HCl","HCl","N/A","Cl.CNCC(=O)C1=CC(=C(O)C=C1)O",0.938,1,3,3]
["S3186","Azatadine dimaleate","h7","L3800-14","in 10mM DMSO","EMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","N/A","Histamine Receptor","Neuronal Signaling","Azatadine (SCH10649,Azatadine Maleate) is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively.",522.55,"3978-86-7",{"v":105,"d":"105.00"},200.94,{"v":105,"d":"105.00"},200.94,"http://selleckchem.com/products/azatadine-dimaleate.html","C20H22N2.2C4H4O4","Dimaleate","SCH10649,Azatadine Maleate","CN1CCC(CC1)=C2C3=CC=CC=C3CCC4=CC=CN=C24.OC(=O)\\C=C/C(O)=O.OC(=O)\\C=C/C(O)=O",1.128,5,0,4]
["S3195","Azlocillin sodium salt","c8","L3800-14","in 10mM DMSO","FDA,CFDA","Martindale:The Extra Pharmacopoeia","N/A","Bacterial","Microbiology","Azlocillin is an acylampicillin with a broad spectrum against bacteria.",484.48,"37091-65-9",{"v":97,"d":"97.00"},200.21,{"v":97,"d":"97.00"},200.21,"http://selleckchem.com/products/azlocillin-sodium-salt.html","C20H23N5O6S.Na","Sodium Salt","N/A","[NaH].CC1(C)SC2C(NC(=O)C(NC(=O)N3CCNC3=O)C4=CC=CC=C4)C(=O)N2C1C(O)=O",0.004,5,3,5]
["S3201","Trifluoperazine 2HCl","f8","L3800-14","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","Phase 4","Dopamine Receptor","Neuronal Signaling","Trifluoperazine (NSC-17474, RP-7623, SKF-5019) 2HCl is a dopamine D2 receptor inhibitor with IC50 of 1.1 nM. Trifluoperazine also inhibits calmodulin (CaM).",480.42,"440-17-5",{"v":88,"d":"88.00"},183.17,{"v":96,"d":"96.00"},199.83,"http://selleckchem.com/products/trifluoperazine-dihydrochloride.html","C21H24F3N3S.2HCl","2HCl","SKF5019","Cl.Cl.CN1CCN(CCCN2C3=C(SC4=CC=C(C=C24)C(F)(F)F)C=CC=C3)CC1",5.739,0,0,5]
["S3603","Betulinic acid","c9","L3800-14","in 10mM DMSO","N/A","N/A","Phase 2","NF-κB,Topoisomerase","DNA Damage/DNA Repair","Betulinic acid (ALS-357, Lupatic acid, Betulic acid), a pentacyclic triterpenoid from Syzigium claviflorum, is a inhibitor of HIV-1 with EC50 of 1.4 μ M. Betulinic acid acts as a new activator of NF-kB.Phase 1/2.",{"v":456.7,"d":"456.70"},"472-15-1",{"v":20,"d":"20.00"},43.79,"<1","N/A","http://selleckchem.com/products/betulinic-acid.html","C30H48O3","free base","ALS-357, Lupatic acid, Betulic acid","CC(=C)C1CCC2(CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC34C)C12)C(O)=O",6.546,1,1,2]
["S3609","Berbamine dihydrochloride","f9","L3800-14","in 10mM DMSO","CFDA","N/A","N/A","Bcr-Abl,CaMK,NF-κB","Angiogenesis","Berbamine (BA, BBM) dihydrochloride, a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan), is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF-κB. Berbamine (BA, BBM) dihydrochloride induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca²⁺/calmodulin-dependent protein kinase II (CaMKII).",681.65,"6078-17-7",{"v":100,"d":"100.00"},{"v":146.7,"d":"146.70"},{"v":100,"d":"100.00"},{"v":146.7,"d":"146.70"},"http://selleckchem.com/products/berbamine-dihydrochloride.html","C37H40N2O6.2HCl","dihydrochloride","BA, BBM","Cl.Cl.COC1=CC2=C3C=C1OC4=C(OC)C(=CC5=C4C(CC6=CC(=C(O)C=C6)OC7=CC=C(CC3N(C)CC2)C=C7)N(C)CC5)OC",7.756,5,1,3]
["S3612","Rosmarinic acid","a10","L3800-14","in 10mM DMSO","DMF","EP9.1,BP2017","N/A","Complement System,IκB/IKK","NF-κB","Rosmarinic acid (RA, Rosemary acid) is a naturally occurring hydroxylated compound. It has the ability to block complement fixation, inhibit lipoxygenase and cyclooxygenase activity and inhibit the expression of CCL11 and CCR3 by suppressing the IKK-β activity in NF-κB activation signaling.",360.31,"20283-92-5",{"v":72,"d":"72.00"},199.83,{"v":24,"d":"24.00"},66.61,"http://selleckchem.com/products/rosmarinic-acid.html","C18H16O8","free base","Rosemary acid","OC(=O)C(CC1=CC=C(O)C(=C1)O)OC(=O)\\C=C\\C2=CC=C(O)C(=C2)O",2.706,3,4,7]
["S3621","Pazufloxacin mesylate","e10","L3800-14","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","Marketed","Bacterial","Microbiology","Pazufloxacin Mesylate (T-3762, Pazucross), also known as Pazucross and T-3762, is a quinolone antibacterial agent used for the intravenous therapy of several infections.",414.41,"163680-77-1",{"v":82,"d":"82.00"},197.87,{"v":82,"d":"82.00"},197.87,"http://selleckchem.com/products/pazufloxacin-mesylate.html","C16H15FN2O4.CH4O3S","methanesulfonate","T-3762, Pazucross","CC1COC2=C(C(=CC3=C2N1C=C(C(O)=O)C3=O)F)C4(N)CC4.C[S](O)(=O)=O",-1.899,3,1,2]
["S3625","Tyramine","h10","L3800-14","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017","N/A","TAAR","GPCR & G Protein","Tyramine (4-hydroxyphenethylamine, para-tyramine, mydrial, uteramin) is a naturally occurring trace amine derived from the amino acid tyrosine and acts as a catecholamine releasing agent.",137.18,"51-67-2",{"v":27,"d":"27.00"},196.82,"<1","N/A","http://selleckchem.com/products/tyramine.html","C8H11NO","free base","4-hydroxyphenethylamine, para-tyramine, mydrial, uteramin","NCCC1=CC=C(O)C=C1",1.015,0,2,2]
["S3627","Tryptamine","a11","L3800-14","in 10mM DMSO","N/A","USP43-NF38","N/A","TAAR","GPCR & G Protein","Tryptamine is a monoamine alkaloid and may play a role as a neuromodulator or neurotransmitter. It is an agonist of hTAAR1. It acts as a non-selective serotonin receptor agonist and serotonin-norepinephrine-dopamine releasing agent (SNDRA).",160.22,"61-54-1",{"v":32,"d":"32.00"},199.73,"<1","N/A","http://selleckchem.com/products/tryptamine.html","C10H12N2","free base","N/A","NCCC1=C[NH]C2=CC=CC=C12",{"v":1.55,"d":"1.550"},0,2,2]
["S3638","Cefamandole nafate","d11","L3800-14","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,BP2017,IP2010","N/A","Bacterial","Microbiology","Cefamandole Nafate is the sodium salt form of cefamandole formyl ester. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall, interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.",512.49,"42540-40-9",{"v":100,"d":"100.00"},195.13,{"v":100,"d":"100.00"},195.13,"http://selleckchem.com/products/cefamandole-nafate.html","C19H17N6O6S2.Na","sodium salt","N/A","[Na+].C[N]1N=NN=C1SCC2=C(N3C(SC2)C(NC(=O)C(OC=O)C4=CC=CC=C4)C3=O)C([O-])=O",-1.169,6,1,9]
["S3641","Osalmid","g11","L3800-14","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","N/A","DNA/RNA Synthesis,RNR","DNA Damage/DNA Repair","Osalmid suppresses ribonucleotide reductase (RNR) activity in a concentration-dependent manner, with a 50% RR activity-inhibitory concentration (IC50) of 8.23 μM.",229.23,"526-18-1",{"v":45,"d":"45.00"},196.31,"<1","N/A","http://selleckchem.com/products/osalmid.html","C13H11NO3","free base","N/A","OC1=CC=C(NC(=O)C2=C(O)C=CC=C2)C=C1",{"v":2.13,"d":"2.130"},1,3,2]
["S3647","Mafenide Acetate","c2","L3800-15","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","N/A","Carbonic Anhydrase","Metabolism","Mafenide Acetate is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.",246.28,"13009-99-9",{"v":49,"d":"49.00"},198.96,{"v":49,"d":"49.00"},198.96,"http://selleckchem.com/products/mafenide-acetate.html","C7H10N2O2S.C2H4O2","acetate","N/A","CC(O)=O.NCC1=CC=C(C=C1)[S](N)(=O)=O",-3.043,3,2,2]
["S3653","Spermidine trihydrochloride","e2","L3800-15","in 10mM DMSO","N/A","N/A","Phase 3","Autophagy,NMDAR","Neuronal Signaling","Spermidine (4-Azaoctamethylenediamine), a natural polyamine produced from putrescine and decarboxylated S-adenosylmethionine (dcSAM) by spermidine synthase, is a novel autophagy inducer and negatively modulates N-methyl-d-aspartate (NMDA).",254.63,"334-50-9",{"v":30,"d":"30.00"},117.82,{"v":50,"d":"50.00"},196.36,"http://selleckchem.com/products/spermidine-trihydrochloride.html","C7H19N3.3HCl","trihydrochloride","4-Azaoctamethylenediamine trihydrochloride","Cl.Cl.Cl.NCCCCNCCCN",-0.024,0,3,7]
["S3657","Promestriene","a3","L3800-15","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia","Phase 3","Estrogen/progestogen Receptor","Endocrinology & Hormones","Promestriene (3-propyl ethyl, 17B-methyl estradiol) is a synthetic estrogen analog that has been reported to significantly improve the symptoms of vaginal atrophy caused by estrogen deprivation in topical application.",328.49,"39219-28-8",{"v":65,"d":"65.00"},197.88,{"v":3,"d":"3.00"},9.13,"http://selleckchem.com/products/promestriene.html","C22H32O2","free base","3-propyl ethyl, 17B-methyl estradiol","CCCOC1=CC2=C(C=C1)C3CCC4(C)C(CCC4C3CC2)OC",5.344,2,0,4]
["S3663","Afloqualone","d3","L3800-15","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,JP17","N/A","GABA Receptor","Neuronal Signaling","Afloqualone (AFQ, HQ-495) is a quinazolinone family GABAergic drug with muscle-relaxant and sedative effects, showing the agonist activity at the β subtype of the GABAa receptor.",{"v":283.3,"d":"283.30"},"56287-74-2",{"v":56,"d":"56.00"},197.67,"<1","N/A","http://selleckchem.com/products/afloqualone.html","C16H14FN3O","free base","HQ-495","CC1=C(C=CC=C1)N2C(=O)C3=C(C=CC(=C3)N)N=C2CF",2.619,2,1,2]
["S3669","Carmustine","g3","L3800-15","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","N/A","DNA/RNA Synthesis","DNA Damage/DNA Repair","Carmustine (bis-chloroethylnitrosourea, BCNU, BiCNU) is a cell-cycle phase nonspecific alkylating antineoplastic agent and used in the treatment of brain tumors and various other malignant neoplasms.",214.05,"154-93-8","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/carmustine.html","C5H9Cl2N3O2","free base","bis-chloroethylnitrosourea, BCNU, BiCNU","ClCCNC(=O)N(CCCl)N=O",1.201,2,1,5]
["S3671","Quinestrol","h3","L3800-15","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia","N/A","Estrogen/progestogen Receptor","Endocrinology & Hormones","Quinestrol (Ethinylestradiol 3-cyclopentyl ether, EE2CPE, W-3566) is a synthetic, steroidal estrogen which is used in hormone replacement therapy and occasionally to treat breast cancer and prostate cancer.",364.52,"152-43-2",{"v":72,"d":"72.00"},197.52,"<1","N/A","http://selleckchem.com/products/quinestrol.html","C25H32O2","free base","Ethinylestradiol 3-cyclopentyl ether, EE2CPE, W-3566","CC12CCC3C(CCC4=C3C=CC(=C4)OC5CCCC5)C1CCC2(O)C#C",6.514,1,0,2]
["S3674","Levamlodipine","c4","L3800-15","in 10mM DMSO","CFDA","N/A","N/A","Calcium Channel","Transmembrane Transporters","Levamlodipine (S-amlodipine) is a pharmacologically active enantiomer of amlodipine which belongs to the dihydropyridine group of calcium channel blocker. It acts on the L-type of calcium channels and its treatment results in vasodilation and a fall in blood pressure.",408.88,"103129-82-4",{"v":81,"d":"81.00"},{"v":198.1,"d":"198.10"},{"v":81,"d":"81.00"},{"v":198.1,"d":"198.10"},"http://selleckchem.com/products/levamlodipine.html","C20H25ClN2O5","free base","S-amlodipine","CCOC(=O)C1=C(COCCN)NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C",1.576,5,2,10]
["S3677","Cinnamic acid","f4","L3800-15","in 10mM DMSO","NDC","Martindale:The Extra Pharmacopoeia,BP2017,EP9.1","N/A","Others","Others","Cinnamic acid (Benzenepropenoic acid, Isocinnamic acid, trans-Cinnamic acid, Phenylacrylic acid), a naturally occurring aromatic fatty acid of low toxicity, induces cytostasis and a reversal of malignant properties of human tumor cells in vitro.",148.16,"140-10-3",{"v":29,"d":"29.00"},195.73,"<1","N/A","http://selleckchem.com/products/cinnamic-acid.html","C9H8O2","free base","trans-Cinnamic acid, Phenylacrylic acid, Cinnamylic acid, 3-Phenylacrylic acid|(E)-Cinnamic acid, Benzenepropenoic acid, Isocinnamic acid","OC(=O)/C=C/C1=CC=CC=C1",1.927,1,0,2]
["S3689","Ethidium bromide","b5","L3800-15","in 10mM DMSO","N/A","USP42-NF37","N/A","Others","Others","Ethidium Bromide (Homidium bromide, EtBr, EB) is an intercalating agent which resembles a DNA base pair and commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.",394.31,"1239-45-8",{"v":78,"d":"78.00"},197.81,{"v":7,"d":"7.00"},17.75,"http://selleckchem.com/products/ethidium-bromide.html","C21H20N3.Br","bromide","Homidium bromide, EtBr, EB","[Br-].CC[N+]1=C2C=C(N)C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N",{"v":1.79,"d":"1.790"},0,2,2]
["S3693","2,6-Dihydroxypurine","e5","L3800-15","in 10mM DMSO","N/A","USP43-NF38","N/A","Others","Others","2,6-Dihydroxypurine (Xanthine, Isoxanthine) is a purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is a product on the pathway of purine degradation.",152.11,"69-89-6",{"v":2,"d":"2.00"},13.15,"<1","N/A","http://selleckchem.com/products/2-6-dihydroxypurine.html","C5H4N4O2","free base","Xanthine, Isoxanthine","O=C1NC(=O)C2=C(N1)N=C[NH]2",-0.718,3,3,0]
["S3701","Benactyzine hydrochloride","a6","L3800-15","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","N/A","AChR","Neuronal Signaling","Benactyzine hydrochloride is a centrally acting muscarinic antagonist. It is used as an antidepressant in the treatment of depression and associated anxiety.",363.88,"57-37-4",{"v":72,"d":"72.00"},197.87,{"v":72,"d":"72.00"},197.87,"http://selleckchem.com/products/benactyzine-hydrochloride.html","C20H25NO3.HCl","hydrochloride","N/A","Cl.CCN(CC)CCOC(=O)C(O)(C1=CC=CC=C1)C2=CC=CC=C2",3.832,2,0,9]
["S3705","Chlorobutanol","d6","L3800-15","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","Phase 4","Fungal","Microbiology","Chlorobutanol (Chlorbutol, Chloreton, Chloretone, Chlortran|, trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic with antibacterial and antifungal properties.",177.46,"57-15-8",{"v":35,"d":"35.00"},197.23,"<1","N/A","http://selleckchem.com/products/chlorobutanol.html","C4H7Cl3O","free base","Chlorbutol, Chloreton, Chloretone, Chlortran","CC(C)(O)C(Cl)(Cl)Cl",1.822,0,0,1]
["S3708","Sulfachloropyridazine","g6","L3800-15","in 10mM DMSO","DMF","N/A","N/A","Antibiotics,Bacterial","Microbiology","Sulfachloropyridazine is an antibiotic used to treat a variety of bacterial infections.",284.72,"80-32-0",{"v":56,"d":"56.00"},196.68,"<1","N/A","http://selleckchem.com/products/sulfachloropyridazine.html","C10H9ClN4O2S","free base","N/A","NC1=CC=C(C=C1)[S](=O)(=O)NC2=CC=C(Cl)N=N2",1.365,4,2,3]
["S3709","Furagin","h6","L3800-15","in 10mM DMSO","Marketed in other country","N/A","Marketed","Bacterial","Microbiology","Furagin (NF-416, F-35, Akritoin, Furazidin, Furazidine) is 2-substituted 5-nitrofuran, chemically and structurally similar to well-known antibacterial compound nitrofurantoin with antimicrobial activities.",264.19,"1672-88-4",{"v":52,"d":"52.00"},196.83,"<1","N/A","http://selleckchem.com/products/furagin.html","C10H8N4O5","free base","NF-416, F-35, Akritoin, Furazidin, Furazidine","[O-][N+](=O)C1=CC=C(O1)/C=C/C=N/N2CC(=O)NC2=O",0.465,4,1,4]
["S3714","Lifitegrast","c7","L3800-15","in 10mM DMSO","FDA,DMF,NDC","N/A","Marketed","Integrin","Cytoskeletal Signaling","Lifitegrast (SAR1118,SHP-606) is a novel small molecule integrin antagonist that inhibits a specific T cell-mediated inflammatory pathway involved in the pathogenesis of DED.",615.48,"1025967-78-5",{"v":100,"d":"100.00"},162.47,"<1","N/A","http://selleckchem.com/products/lifitegrast.html","C29H24Cl2N2O7S","free base","SAR1118,SHP-606","C[S](=O)(=O)C1=CC=CC(=C1)CC(NC(=O)C2=C(Cl)C=C3CN(CCC3=C2Cl)C(=O)C4=CC=C5C=COC5=C4)C(O)=O",{"v":4.79,"d":"4.790"},6,1,7]
["S3722","Isavuconazole","g7","L3800-15","in 10mM DMSO","EMA","N/A","N/A","Fungal","Microbiology","Isavuconazole (BAL-4815, RO-0094815) is a new extended-spectrum triazole with activity against yeasts, molds, and dimorphic fungi that inhibits cytochrome P450 (CYP)-dependent 14α-lanosterol demethylation, which is essential for fungal cell membrane ergosterol synthesis.",437.47,"241479-67-4",{"v":87,"d":"87.00"},198.87,"<1","N/A","http://selleckchem.com/products/isavuconazole.html","C22H17F2N5OS","free base","BAL-4815, RO-0094815","CC(C1=NC(=CS1)C2=CC=C(C=C2)C#N)C(O)(C[N]3C=NC=N3)C4=CC(=CC=C4F)F",3.904,3,0,6]
["S3726","Selexipag","b8","L3800-15","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Prostaglandin Receptor","Immunology & Inflammation","Selexipag (NS-304, ACT-293987) is an orally active, first-in-class, selective prostacyclin IP receptor agonist with Ki value of 260 nM for human IP, whereas Ki values > 10,000 nM are measured at the other human G-protein-coupled prostanoid receptors (EP1-4, DP, FP and TP).",496.62,"475086-01-2",{"v":99,"d":"99.00"},199.35,"<1","N/A","http://selleckchem.com/products/selexipag.html","C26H32N4O4S","free base","NS-304, ACT-293987","CC(C)N(CCCCOCC(=O)N[S](C)(=O)=O)C1=NC(=C(N=C1)C2=CC=CC=C2)C3=CC=CC=C3",3.996,6,1,12]
["S3729","Iron sucrose","e8","L3800-15","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia","Marketed","Others","Others","Iron sucrose (Iron saccharate, Sucroferric oxyhydroxide) is an intravenously administered iron product indicated in the treatment of iron deficiency anemia.",736.06,"8047-67-4",{"v":100,"d":"100.00"},135.86,{"v":100,"d":"100.00"},135.86,"http://selleckchem.com/products/iron-sucrose.html","C18H24Fe2O24","Iron saccharate","Iron saccharate, Sucroferric oxyhydroxide","[Fe+3].[Fe+3].OC(C(O)C(O)C([O-])=O)C(O)C([O-])=O.OC(C(O)C(O)C([O-])=O)C(O)C([O-])=O.OC(C(O)C(O)C([O-])=O)C(O)C([O-])=O",-16.899,0,12,15]
["S3733","Boceprevir","a9","L3800-15","in 10mM DMSO","FDA,EMA","N/A","Marketed","COVID-19,HCV Protease","Proteases","Boceprevir (EBP 520, SCH 503034) is an oral, direct acting hepatitis C virus (HCV) protease inhibitor with Ki value of 14 nM for NS3. It is used in combination with other antiviral agents in the treatment of chronic hepatitis C, genotype 1.",519.68,"394730-60-0",{"v":100,"d":"100.00"},192.43,"<1","N/A","http://selleckchem.com/products/boceprevir.html","C27H45N5O5","free base","EBP 520, SCH 503034","CC(C)(C)NC(=O)NC(C(=O)N1CC2C(C1C(=O)NC(CC3CCC3)C(=O)C(N)=O)C2(C)C)C(C)(C)C",1.623,5,4,10]
["S3739","Calcipotriene","d9","L3800-15","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","Marketed","Vitamin","Metabolism","Calcipotriene (Calcipotriol, MC903) is a synthetic derivative of calcitriol, a form of vitamin D. It can induce differentiation and suppresses proliferation of keratinocytes, reversing abnormal keratinocyte changes in psoriasis, and lead to normalization of epidermal growth.  Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.",{"v":412.6,"d":"412.60"},"112965-21-6",{"v":82,"d":"82.00"},198.74,"<1","N/A","http://selleckchem.com/products/calcipotriene.html","C27H40O3","free base","Calcipotriol, MC903","CC(\\C=C\\C(O)C1CC1)C2CCC3/C(CCCC23C)=C/C=C\\4CC(O)CC(O)C4=C",4.679,0,3,5]
["S3745","Balsalazide disodium","g9","L3800-15","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP39-NF34","Marketed","Immunology & Inflammation related,Interleukins,STAT","Immunology & Inflammation","Balsalazide Disodium is the disodium salt form of balsalazide, an aminosalicylate and oral prodrug that is enzymatically cleaved in the colon to produce the anti-inflammatory agent mesalazine. Balsalazide Disodium suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway.",437.31,"150399-21-6",{"v":87,"d":"87.00"},198.94,{"v":87,"d":"87.00"},198.94,"http://selleckchem.com/products/balsalazide-disodium.html","C17H13N3O6.2H2O.2Na","disodium salt dihydrate","N/A","O.O.[Na+].[Na+].OC1=CC=C(C=C1C([O-])=O)N=NC2=CC=C(C=C2)C(=O)NCCC([O-])=O",-0.838,3,2,7]
["S3746","Lumefantrine","h9","L3800-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,Ph.Int_6th","Phase 2","Anti-infection","Microbiology","Lumefantrine (benflumetol) is an antimalarial agent used to treat acute uncomplicated malaria.",528.94,"82186-77-4",{"v":13,"d":"13.00"},24.58,"<1","N/A","http://selleckchem.com/products/lumefantrine.html","C30H32Cl3NO","free base","benflumetol","CCCCN(CCCC)CC(O)C1=CC(=CC\\2=C1C3=C(C=C(Cl)C=C3)C2=C/C4=CC=C(Cl)C=C4)Cl",9.196,0,1,10]
["S3750","Sodium benzoate","b10","L3800-15","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,JP17,BP2017,IP2010","Phase 2/3","Others","Others","Sodium benzoate (Benzoic acid sodium salt) is a preservative and uesd as a food additive which is bacteriostatic and fungistatic under acidic conditions.",{"v":144.1,"d":"144.10"},"532-32-1",{"v":3,"d":"3.00"},20.82,{"v":28,"d":"28.00"},194.31,"http://selleckchem.com/products/sodium-benzoate.html","C7H5O2.Na","sodium salt","Benzoic acid sodium salt","[Na+].[O-]C(=O)C1=CC=CC=C1",-0.015,0,0,1]
["S3758","Sinomenine hydrochloride","g10","L3800-15","in 10mM DMSO","CFDA","CP2005,EP9.2,BP2017","N/A","Autophagy,Immunology & Inflammation related","Immunology & Inflammation","Sinomenine (SN, Cucoline, Kukoline, Sabianine A), extracted from the Chinese medicinal plant, sinomenium acutum, is a potent anti-inflammatory and neuroprotective agent.",365.85,"6080-33-7",{"v":73,"d":"73.00"},199.54,"N/A","N/A","http://selleckchem.com/products/sinomenine-hydrochloride.html","C19H23NO4.HCl","hydrochloride","Cucoline hydrochloride, Kukoline hydrochloride, Sabianine A hydrochloride","Cl.COC1=C(O)C2=C(CC3C4C=C(OC)C(=O)CC24CCN3C)C=C1",2.056,3,1,2]
["S3766","Tanshinone IIA sulfonate sodium","b11","L3800-15","in 10mM DMSO","CFDA","N/A","N/A","Calcium Channel,P2 Receptor,P450 (e.g. CYP17)","Metabolism","Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivative of tanshinone IIA isolated as the main pharmacologically active natural compound from a traditional Chinese herbal medicine, the dried root of Salvia miltiorrhiza Bunge known as Danshen. Sodium tanshinone IIA sulfonate (STS) is a potent negative allosteric modulator of the human purinergic receptor P2X7. Sodium tanshinone IIA sulfonate (STS) inhibits the activity of CYP3A4 and store-operated Ca2+ entry (SOCE) through store-operated Ca2+ channels (SOCC) via downregulating the expression of transient receptor potential canonical proteins (TRPC).",396.39,"69659-80-9",{"v":79,"d":"79.00"},{"v":199.3,"d":"199.30"},"N/A","N/A","http://selleckchem.com/products/tanshinone-iia-sulfonate-sodium.html","C19H17O6S.Na","sodium salt","N/A","[Na+].CC1=C(OC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C)[S]([O-])(=O)=O",1.873,3,0,1]
["S3773","Tyrosol","e11","L3800-15","in 10mM DMSO","DMF","USP42-NF37","N/A","NF-κB","NF-κB","Tyrosol (4-Hydroxyphenylethanol, 4-Hydroxyphenethyl alcohol, 2-(4-Hydroxyphenyl)ethanol) is an antioxidant that is naturally present in several foods such as wines and green tea and is present most abundantly in olives.  Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects.",138.16,"501-94-0",{"v":27,"d":"27.00"},195.43,"N/A","N/A","http://selleckchem.com/products/tyrosol.html","C8H10O2","free base","4-Hydroxyphenylethanol, 4-Hydroxyphenethyl alcohol, 2-(4-Hydroxyphenyl)ethanol","OCCC1=CC=C(O)C=C1",1.304,0,2,2]
["S3779","cis-Anethole","a2","L3800-16","in 10mM DMSO","N/A","BP2019","N/A","Others","Others","Anethole ((Z)-Anethole, Cis-p-Propenylanisole, Cis-p-Anethole) has two isomers, the cis(Z) isomer being 15-38 times more toxic to animal than the trans(E) isomer. cis-Anethole is found in anise and Only a low level is permitted in flavours.",{"v":148.2,"d":"148.20"},"104-46-1","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/cis-anethole.html","C10H12O","free base","(Z)-Anethole, Cis-p-Propenylanisole, Cis-p-Anethole","COC1=CC=C(\\C=C\\C)C=C1",2.767,1,0,2]
["S3785","Notoginsenoside R1","d2","L3800-16","in 10mM DMSO","N/A","CP2005","N/A","Akt,ERK,PAI-1,PI3K","Metabolism","Notoginsenoside R1 (Sanchinoside R1) is the main ingredient with cardiovascular activity in Panax notoginseng. It inhibits TNF-α-induced PAI-1 overexpression via extracellular signal-related kinases (ERK1/2) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling pathways.",933.13,"80418-24-2",{"v":100,"d":"100.00"},107.17,"N/A","N/A","http://selleckchem.com/products/notoginsenoside-r1.html","C47H80O18","free base","Sanchinoside R1, NG-R1, NGR1","CC(C)=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C2CCC3(C)C2C(O)CC4C5(C)CCC(O)C(C)(C)C5C(CC34C)OC6OC(CO)C(O)C(O)C6OC7OCC(O)C(O)C7O",{"v":-0.11,"d":"-0.110"},6,12,12]
["S3794","Palmitic acid","g2","L3800-16","in 10mM DMSO","DMF,NDC","USP42-NF37,EP9.1,BP2017,IP2010","N/A","Others","Others","Palmitic acid (Hexadecanoic acid, Cetylic acid) is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity.",256.42,"57-10-3",{"v":51,"d":"51.00"},198.89,"N/A","N/A","http://selleckchem.com/products/palmitic-acid.html","C16H32O2","free base","hexadecanoic acid, Cetylic acid","CCCCCCCCCCCCCCCC(O)=O",6.393,1,0,14]
["S3796","Rebaudioside A","h2","L3800-16","in 10mM DMSO","N/A","N/A","Phase 1","Carbohydrate Metabolism","Metabolism","Rebaudioside A (Stevia Extract, Reb A, Glycoside A3, Stevioside A3), an natural sweetening ingredient extracted from the stevia leaf, is used in powder or liquid form to heighten sweetening intensity and improve taste. Rebaudioside A is a steviol glycoside, α-glucosidase inhibitor with IC50 of 35.01 μg/ml.can inhibit ATP-sensitive K+-channels.",967.01,"58543-16-1",{"v":40,"d":"40.00"},41.36,"N/A","N/A","http://selleckchem.com/products/rebaudioside-a.html","C44H70O23","free base","Reb A, Glycoside A3, Stevioside A3","CC12CCCC(C)(C1CCC34CC(=C)C(CCC23)(C4)OC5OC(CO)C(O)C(OC6OC(CO)C(O)C(O)C6O)C5OC7OC(CO)C(O)C(O)C7O)C(=O)OC8OC(CO)C(O)C(O)C8O",-3.476,9,14,13]
["S3802","Trigonelline Hydrochloride","c3","L3800-16","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Bacterial","Microbiology","Trigonelline (Nicotinic acid N-methylbetaine, Coffearine, Gynesine), a major alkaloid component of fenugreek, has hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities, and also has been shown to reduce diabetic auditory neuropathy and platelet aggregation.",{"v":173.6,"d":"173.60"},"6138-41-6",{"v":18,"d":"18.00"},103.69,"N/A","N/A","http://selleckchem.com/products/trigonelline-hydrochloride.html","C7H8NO2.Cl","chloride","Nicotinic acid N-methylbetaine Hydrochloride, Coffearine Hydrochloride, Gynesine Hydrochloride","[Cl-].C[N+]1=CC(=CC=C1)C(O)=O",{"v":-1.61,"d":"-1.610"},1,0,1]
["S3809","Imperatorin","g3","L3800-16","in 10mM DMSO","N/A","BP2019;EP9.2;CP2005","N/A","Calcium Channel","Transmembrane Transporters","Imperatorin (Ammidin, Marmelosin, Pentosalen, 8-Isoamylenoxypsoralen), a naturally occurring psoralen-type furanocoumarin, is a potent myorelaxant agent and acts as a calcium antagonist on vascular smooth muscle.",270.28,"482-44-0",{"v":54,"d":"54.00"},199.79,"N/A","N/A","http://selleckchem.com/products/imperatorin.html","C16H14O4","free base","Ammidin, Marmelosin, Pentosalen, 8-Isoamylenoxypsoralen, 8-Isopentenyloxypsoralene","CC(C)=CCOC1=C2OC(=O)C=CC2=CC3=C1OC=C3",3.652,4,0,3]
["S3812","Monocrotaline","b4","L3800-16","in 10mM DMSO","N/A","BP2023","N/A","Others","Others","Monocrotaline (MCT, Crotaline) is an 11-membered macrocyclic pyrrolizidine alkaloid (PA) that causes a pulmonary vascular syndrome in rats characterized by proliferative pulmonary vasculitis, pulmonary hypertension, and cor pulmonale.",325.36,"315-22-0",{"v":65,"d":"65.00"},199.78,"N/A","N/A","http://selleckchem.com/products/monocrotaline.html","C16H23NO6","free base","Crotaline","CC1C(=O)OC2CCN3CC=C(COC(=O)C(C)(O)C1(C)O)C23",-0.015,4,0,0]
["S3824","Quercitrin","e4","L3800-16","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Immunology & Inflammation related","Immunology & Inflammation","Quercitrin (3-rhamnosyl quercetin, Sophoretin, Meletin, Xanthaurine), a glycoside of quercetin, has been found as a main bioactive constituent in T. sinensis leaves and has antioxidant, anti-inflammatory, and anti-allergic activities.",448.38,"522-12-3",{"v":89,"d":"89.00"},198.49,"N/A","N/A","http://selleckchem.com/products/quercitrin.html","C21H20O11","free base","3-rhamnosyl quercetin, Sophoretin, Meletin, Xanthaurine","CC1OC(OC2=C(OC3=C(C(=CC(=C3)O)O)C2=O)C4=CC(=C(O)C=C4)O)C(O)C(O)C1O",0.589,4,7,3]
["S3842","Isoquercitrin","a5","L3800-16","in 10mM DMSO","N/A","BP2019","N/A","Wnt/beta-catenin","Stem Cells & Wnt","Isoquercitrin (Hirsutrin, 3-Glucosylquercetin, Quercetin 3-o-glucopyranoside), a flavonoid compound with anticancer activity isolated from Bidens bipinnata L, is an inhibitor of Wnt/β-catenin that acts downstream of the β-catenin nuclear translocation.",464.38,"482-35-9",{"v":92,"d":"92.00"},198.11,"N/A","N/A","http://selleckchem.com/products/isoquercitrin.html","C21H20O12","free base","Hirsutrin, 3-Glucosylquercetin, Quercetin 3-o-glucopyranoside","OCC1OC(OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(O)C=C4)O)C(O)C(O)C1O",{"v":-0.3,"d":"-0.300"},4,8,4]
["S3847","Panaxatriol","d5","L3800-16","in 10mM DMSO","CFDA","N/A","N/A","Others","Others","Panaxatriol is a triterpene sapogenin originally found in species of Panax (ginseng) and exhibits anti-inflammatory, hepatoprotective, anti-arrhythmic, and antioxidative activities.",476.73,"32791-84-7",{"v":95,"d":"95.00"},199.27,"N/A","N/A","http://selleckchem.com/products/panaxatriol.html","C30H52O4","free base","N/A","CC1(C)CCCC(C)(O1)C2CCC3(C)C2C(O)CC4C5(C)CCC(O)C(C)(C)C5C(O)CC34C",4.285,1,3,1]
["S3849","D-Galactose","e5","L3800-16","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,BP2013,IP2010","N/A","Others","Others","D-Galactose (D-Galactopyranose, D-(+)-Galactose) is an aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins and is converted enzymatically into D-glucose for metabolism or polysaccharides for storage. It accelerates senescence in invertebrates and mammals and has been used as a model for aging.",180.16,"59-23-4",{"v":36,"d":"36.00"},199.82,"N/A","N/A","http://selleckchem.com/products/d-galactose.html","C6H12O6","free base","D-Galactopyranose, D-(+)-Galactose","OCC1OC(O)C(O)C(O)C1O",-2.514,1,4,1]
["S3853","Perillyl alcohol","h5","L3800-16","in 10mM DMSO","N/A","N/A","Phase 1/2","Ras","Apoptosis","Perillyl alcohol (Perilla alcohol, Isocarveol) is a monoterpene isolated from the essential oils of lavendin, peppermint, spearmint, cherries, celery seeds, and several other plants.",152.23,"536-59-4","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/perillyl-alcohol.html","C10H16O","free base","Perilla alcohol, Isocarveol","CC(=C)C1CCC(=CC1)CO",2.411,0,1,2]
["S3858","Lawsone","c6","L3800-16","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Lawsone (Hennotannic acid, 2-hydroxy-1,4-naphthoquinone) is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well as in the flower of water hyacinth (Eichhornia crassipes).",174.15,"83-72-7",{"v":34,"d":"34.00"},195.23,"N/A","N/A","http://selleckchem.com/products/lawsone.html","C10H6O3","free base","Hennotannic acid, 2-hydroxy-1,4-naphthoquinone","OC1=CC(=O)C2=C(C=CC=C2)C1=O",{"v":1.22,"d":"1.220"},2,1,0]
["S3868","Harmine","g6","L3800-16","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","MAO,PPAR","Metabolism","Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγ and cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.",212.25,"442-51-3",{"v":42,"d":"42.00"},197.88,"N/A","N/A","http://selleckchem.com/products/harmine.html","C13H12N2O","free base","Telepathine","COC1=CC2=C(C=C1)C3=CC=NC(=C3[NH]2)C",2.438,2,1,1]
["S3876","Indigo","b7","L3800-16","in 10mM DMSO","DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,JP16,IP2010","Phase 2","Dyes","Others","Indigo (Indigotin) dye is an organic compound with a distinctive blue color. It is extracted from the leaves of certain plants or synthetic.",262.26,"482-89-3",{"v":33,"d":"33.00"},125.83,"N/A","N/A","http://selleckchem.com/products/indigo.html","C16H10N2O2","free base","Indigotin","O=C1\\C(NC2=C1C=CC=C2)=C\\3NC4=C(C=CC=C4)C3=O",2.106,2,2,0]
["S3883","Protopine","d7","L3800-16","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","ADC Cytotoxin,Calcium Channel","Transmembrane Transporters","Protopine (Corydinine, Fumarine, Biflorine, Macleyine), an alkaloid present in different plants, has been shown to exhibit a number of activities, such as inhibition of calcium influx through both voltage and receptor-operated channels and inhibition of rabbit blood platelet aggregation. It also possesses anti-cholinergic and anti-histaminic as well as anti-bacterial activities.",353.37,"130-86-9",{"v":30,"d":"30.00"},{"v":84.9,"d":"84.90"},"N/A","N/A","http://selleckchem.com/products/protopine.html","C20H19NO5","free base","Corydinine, Fumarine, Biflorine, Macleyine","CN1CCC2=C(C=C3OCOC3=C2)C(=O)CC4=C(C1)C5=C(OCO5)C=C4",2.953,5,0,0]
["S3892","Isopsoralen","h7","L3800-16","in 10mM DMSO","N/A","CP2005","N/A","ADC Cytotoxin,Immunology & Inflammation related","Immunology & Inflammation","Isopsoralen (Angelicin), also known as angelicin, is a constituent of roots and leaves of angelica with anti-inflammatory activity and regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways. It also shows antiviral activity against gammaherpesviruses.",186.16,"523-50-2",{"v":14,"d":"14.00"},{"v":75.2,"d":"75.20"},"N/A","N/A","http://selleckchem.com/products/isopsoralen.html","C11H6O3","free base","angelicin","O=C1OC2=C(C=C1)C=CC3=C2C=CO3",2.203,3,0,0]
["S3897","(-)-Arctigenin","c8","L3800-16","in 10mM DMSO","N/A","N/A","Phase 2","Influenza Virus","Microbiology","(-)-Arctigenin, a lignan found in certain plants of the Asteraceae, exerts biological activities including anti-inflammatory, antiviral and anticancer.",372.41,"7770-78-7",{"v":74,"d":"74.00"},198.71,"N/A","N/A","http://selleckchem.com/products/neg-rotation-arctigenin.html","C21H24O6","free base","N/A","COC1=C(O)C=CC(=C1)CC2C(COC2=O)CC3=CC=C(OC)C(=C3)OC",3.743,5,1,7]
["S3898","Hydroxy Camptothecine","d8","L3800-16","in 10mM DMSO","CFDA","N/A","N/A","Topoisomerase","DNA Damage/DNA Repair","Hydroxy Camptothecine (10-Hydroxycamptothecin, Hydroxycamptothecine) is a cell-permeable powerful DNA topoisomerase I inhibitor. It has selective inhibitory effect on the phosphorylation of histone H1 and H3, but less effect on other histones.",364.35,"64439-81-2",{"v":29,"d":"29.00"},79.59,"N/A","N/A","http://selleckchem.com/products/hydroxy-camptothecine.html","C20H16N2O5","free base","10-Hydroxycamptothecin, Hydroxycamptothecine","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=CC5=C(C=CC(=C5)O)N=C34)C2=O",1.504,4,1,1]
["S3905","Iso-Steviol","g8","L3800-16","in 10mM DMSO","N/A","N/A","Phase 2","Others","Others","Isosteviol (ISV) is mainly obtained by acid hydrolysis of stevioside, the sweet food additive extracted from the plant Stevia Rebaudiana Bertoni (Bertoni). It possesses various biological activities including anti-hyperglycemic, anti-hypertensive, anti-tumor, anti-inflammatory, and antioxidant effects.",318.45,"27975-19-5",{"v":63,"d":"63.00"},197.83,"N/A","N/A","http://selleckchem.com/products/iso-steviol.html","C20H30O3","free base","N/A","CC12CCC3C4(C)CCCC(C)(C4CCC3(CC1=O)C2)C(O)=O",3.924,2,0,1]
["S3914","α-Hederin","b9","L3800-16","in 10mM DMSO","N/A","BP2019","N/A","Others","Apoptosis","α-hederin is a water-soluble pentacyclic triterpenoid saponin which has shown hemolytic and apoptotic properties.",750.96,"27013-91-8",{"v":100,"d":"100.00"},133.16,"N/A","N/A","http://selleckchem.com/products/alpha-hederin.html","C41H66O12","free base","N/A","CC1OC(OC2C(O)C(O)COC2OC3CCC4(C)C(CCC5(C)C4CC=C6C7CC(C)(C)CCC7(CCC56C)C(O)=O)C3(C)CO)C(O)C(O)C1O",3.261,5,6,6]
["S3923","Ginsenoside Rg1","f9","L3800-16","in 10mM DMSO","NDC","CP2005,EP9.2,BP2017","N/A","Beta Amyloid,NF-κB","Neuronal Signaling","Ginsenoside Rg1 (Ginsenoside A2, Panaxoside A, Panaxoside Rg1, Sanchinoside C1, Sanchinoside Rg1), one of the major active components of ginseng, is identified as a protopanaxatriol-type and has pharmacological actions such as neuroprotective and anti-tumor effects on various cancer types. Ginsenoside Rg1 reduces cerebral Aβ levels and NF-κB nuclear translocation.",801.01,"22427-39-0",{"v":100,"d":"100.00"},124.84,"N/A","N/A","http://selleckchem.com/products/ginsenoside-rg1.html","C42H72O14","free base","Ginsenoside A2, Panaxoside A, Panaxoside Rg1, Sanchinoside C1, Sanchinoside Rg1","CC(C)=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C2CCC3(C)C2C(O)CC4C5(C)CCC(O)C(C)(C)C5C(CC34C)OC6OC(CO)C(O)C(O)C6O",1.126,4,10,10]
["S3926","Forsythin","a10","L3800-16","in 10mM DMSO","N/A","CP2005","N/A","PDE","GPCR & G Protein","Forsythin (FOR, Phillyrin) is an active ingredient extracted from the fruit of the medicinal plant Forsythia suspensa (Thunb.) Vahl and has been shown to have antioxidant, antibacterial and antiinflammatory properties.",534.55,"487-41-2",{"v":100,"d":"100.00"},187.07,"N/A","N/A","http://selleckchem.com/products/forsythin.html","C27H34O11","free base","Phillyrin","COC1=CC=C(C=C1OC)C2OCC3C2COC3C4=CC(=C(OC5OC(CO)C(O)C(O)C5O)C=C4)OC",0.479,7,4,8]
["S3935","Nonivamide","d10","L3800-16","in 10mM DMSO","NDC,HMA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017","N/A","TRP Channel","Transmembrane Transporters","Nonivamide (pelargonic acid vanillylamide, Pseudocapsaicin, Vanillyl-N-nonylamide), present in chili peppers, is commonly manufactured synthetically and used as a food additive to add pungency to seasonings, flavorings, and spice blends. Nonivamide is a agonist, which exhibits 4d-EC50 value of 5.1 mg/L in static toxicity tests.",{"v":293.4,"d":"293.40"},"2444-46-4",{"v":58,"d":"58.00"},197.68,"<1","N/A","https://www.selleckchem.com/products/nonivamide.html","C17H27NO3","free base","pelargonic acid vanillylamide, Pseudocapsaicin, Vanillyl-N-nonylamide","CCCCCCCCC(=O)NCC1=CC(=C(O)C=C1)OC",4.103,2,2,10]
["S3945","L-Cycloserine","h10","L3800-16","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,Ph.Int_6th,JP17,IP2010","N/A","Transferase","Metabolism","L-Cycloserine (Levcycloserine, Levcicloserina, Levcycloserinum, (-)-Cycloserine, (S)-Cycloserine) is a potent inhibitor of the sphingolipid pathway via inhibiting 3-ketodihydrosphingosine synthetase. It also inhibits HIV-1 cytopathic effects, replication, and infectivity.",102.09,"339-72-0",{"v":8,"d":"8.00"},78.36,{"v":20,"d":"20.00"},195.91,"http://selleckchem.com/products/l-cycloserine.html","C3H6N2O2","free base","Levcycloserine, Levcicloserina, Levcycloserinum, (-)-Cycloserine, (S)-Cycloserine","NC1CONC1=O",-1.788,2,2,0]
["S3956","Tetramethylpyrazine","c11","L3800-16","in 10mM DMSO","CFDA","N/A","N/A","Immunology & Inflammation related","Immunology & Inflammation","Tetramethylpyrazine (ligustrazine, TMP) is a natural compound isolated from Chinese herbal medicine Ligusticum wallichii (Chuan Xiong) with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.",136.19,"1124-11-4",{"v":27,"d":"27.00"},198.25,"N/A","N/A","http://selleckchem.com/products/tetramethylpyrazine.html","C8H12N2","free base","ligustrazine","CC1=NC(=C(C)N=C1C)C",0.659,2,0,0]
["S3957","Gamma-Oryzanol","d11","L3800-16","in 10mM DMSO","CFDA,PMDA","N/A","N/A","DNA Methyltransferase","Epigenetics","Gamma-oryzanol (GO), a nutriactive phytochemical naturally occurring in crude rice bran oil, is an antioxidant compound used to treat hyperlipidemia, disorders of menopause and to increase the muscle mass.  γ-Oryzanol is a potent DNA methyltransferases (DNMTs) inhibitor in the striatum of mice. γ-Oryzanol significantly inhibits the activities of DNMT1 (IC50=3.2 μM), DNMT3a (IC50=22.3 μM).",602.89,"11042-64-1",{"v":100,"d":"100.00"},165.87,"N/A","N/A","http://selleckchem.com/products/gamma-oryzanol.html","C40H58O4","free base","N/A","COC1=CC(=CC=C1O)/C=C/C(=O)OC2CCC34CC35CCC6(C)C(CCC6(C)C5CCC4C2(C)C)C(C)CCC=C(C)C",9.806,3,1,9]
["S3965","Vanillyl Butyl Ether","g11","L3800-16","in 10mM DMSO","NDC","N/A","N/A","Others","Others","Vanillyl Butyl Ether (4-(Butoxymethyl)-2-methoxyphenol), an ether of monohydroxybenzoic acid, is added to food products as a flavoring agent. It is also present in cosmetics and personal care products as a fragrance ingredient, oral care agent, hair conditioning agent, and warming or cooling agent.",210.27,"82654-98-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/vanillyl-butyl-ether.html","C12H18O3","Ether","4-(Butoxymethyl)-2-methoxyphenol","CCCCOCC1=CC(=C(O)C=C1)OC",2.704,2,1,6]
["S3968","Histamine","b2","L3800-17","in 10mM DMSO","FDA,EMA,HMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","Marketed","Histamine Receptor","Immunology & Inflammation","Histamine, an organic nitrogenous compound, is involved in local immune responses regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. It is a potent H1 and H2 receptor agonist.",111.15,"51-45-6",{"v":22,"d":"22.00"},197.93,"N/A","N/A","http://selleckchem.com/products/histamine.html","C5H9N3","free base","N/A","NCCC1=C[NH]C=N1",-0.714,1,2,2]
["S3974","(+)-Catechin hydrate","f2","L3800-17","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","COX","Immunology & Inflammation","(+)-Catechin hydrate is a plant derived polyphenolic anti-oxidants with phytotoxic properties. (+)-Catechin hydrate is a frequent component of traditional herbal remedies, such as Uncaria rhynchophylla.  (+)-Catechin hydrate inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.",290.27,"225937-10-0",{"v":58,"d":"58.00"},199.81,"N/A","N/A","http://selleckchem.com/products/catechin-hydrate.html","C15H14O6.xH2O","hydrate","N/A","OC1CC2=C(OC1C3=CC(=C(O)C=C3)O)C=C(O)C=C2O",2.021,1,5,1]
["S3979","Zinc Undecylenate","a3","L3800-17","in 10mM DMSO","CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,USP40-NF35,IP2010","N/A","Fungal","Microbiology","Zinc Undecylenate (Zinc diundec-10-enoate, Zinc 10-undecenoate) is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.",431.92,"557-08-4",{"v":36,"d":"36.00"},83.35,"N/A","N/A","http://selleckchem.com/products/zinc-undecylenate.html","C22H38O4Zn","zinc salt","Zinc diundec-10-enoate, Zinc 10-undecenoate","[Zn++].[O-]C(=O)CCCCCCCCC=C.[O-]C(=O)CCCCCCCCC=C",4.494,0,0,18]
["S3984","Nordihydroguaiaretic acid (NDGA)","e3","L3800-17","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia","N/A","Apoptosis related,Autophagy,Epigenetic Reader Domain,Ferroptosis,HER2,IGF-1R,Lipoxygenase","Metabolism","Nordihydroguaiaretic acid (NDGA) is a phenolic antioxidant found in the leaves and twigs of the evergreen desert shrub, Larrea tridentata (Sesse and Moc. ex DC) Coville (creosote bush). It is a recognized inhibitor of lipoxygenase (LOX) and has antioxidant and free radical scavenging properties. Nordihydroguaiaretic acid (NDGA) is a cytotoxic insulin-like growth factor-I receptor (IGF-1R)/HER2 inhibitor and induces apoptosis.",302.36,"500-38-9",{"v":60,"d":"60.00"},198.44,"<1","N/A","http://selleckchem.com/products/nordihydroguaiaretic-acid.html","C18H22O4","free base","N/A","CC(CC1=CC=C(O)C(=C1)O)C(C)CC2=CC=C(O)C(=C2)O",4.708,0,4,5]
["S3987","L-Tryptophan","h3","L3800-17","in 10mM DMSO","DMF,CFDA,NDC","USP42-NF37,KP Ⅹ,JP17","N/A","Others","Others","L-tryprophan is an essential amino acid that acts like a natural mood regulator that is necessary for normal growth in infants and for nitrogen balance in adults.",204.23,"73-22-3",{"v":11,"d":"11.00"},53.86,"N/A","N/A","http://selleckchem.com/products/l-tryptophan.html","C11H12N2O2","free base","N/A","NC(CC1=C[NH]C2=C1C=CC=C2)C(O)=O",-1.312,1,2,3]
["S3995","Guaiazulene","d4","L3800-17","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017","N/A","Others","Others","Guaiazulene (Azulon, Vetivazulen) is a bicyclic sesquiterpene that is a constituent of some essential oils, mainly oil of guaiac and chamomile oil, which also serve as its commercial sources.",{"v":198.3,"d":"198.30"},"489-84-9",{"v":39,"d":"39.00"},196.67,"N/A","N/A","http://selleckchem.com/products/guaiazulene.html","C15H18","free base","Azulon, Vetivazulen","CC(C)C1=CC2=C(C)C=CC2=C(C)C=C1",4.905,0,0,1]
["S3996","Thioctic acid","e4","L3800-17","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017","Marketed","Others","Others","Thioctic acid (DL-α-Lipoic acid) is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form., Thioctic acid (DL-α-Lipoic acid)是环状二硫抗氧化剂，可与其还原性二硫酚形式相互转换。",206.33,"1077-28-7",{"v":41,"d":"41.00"},198.71,"N/A","N/A","http://selleckchem.com/products/thioctic-acid.html","C8H14O2S2","free base","DL-α-Lipoic Acid","OC(=O)CCCCC1CCSS1",2.258,1,0,5]
["S3999","α-santonin","h4","L3800-17","in 10mM DMSO","N/A","JP17","Marketed","Parasite","Microbiology","α-santonin, a naturally occurring sesquiterpene lactone, is a potent antiparasitic agent.",{"v":246.3,"d":"246.30"},"481-06-1",{"v":49,"d":"49.00"},198.94,"N/A","N/A","http://selleckchem.com/products/alpha-santonin.html","C15H18O3","free base","N/A","CC1C2CCC3(C)C=CC(=O)C(=C3C2OC1=O)C",2.601,3,0,0]
["S4003","Lithocholic acid","d5","L3800-17","in 10mM DMSO","N/A","USP42-NF37","N/A","FXR","Metabolism","Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity, its toxic effect can be protected after it activates the vitamin D receptor, PXR and FXR.",376.57,"434-13-9",{"v":75,"d":"75.00"},199.17,"<1","N/A","http://selleckchem.com/products/lithocholic-acid.html","C24H40O3","free base","N/A","CC(CCC(O)=O)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C",5.184,1,1,4]
["S4007","Pentamidine isethionate","f5","L3800-17","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37,IP2010","N/A","phosphatase","Metabolism","Pentamidine is an inhibitor of PRL Phosphatases and also inhibits synthesis of DNA, RNA and protein.",592.68,"140-64-7",{"v":100,"d":"100.00"},168.73,{"v":100,"d":"100.00"},168.73,"http://selleckchem.com/products/pentamidine-isethionate.html","C19H24N4O2.2C2H6O4S","isethionate","N/A","NC(=N)C1=CC=C(OCCCCCOC2=CC=C(C=C2)C(N)=N)C=C1.OCC[S](O)(=O)=O.OCC[S](O)(=O)=O",0.751,2,4,14]
["S4011","Ampiroxicam","a6","L3800-17","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,JP17","Marketed","COX","Neuronal Signaling","Ampiroxicam (CP 65703) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.",447.46,"99464-64-9",{"v":90,"d":"90.00"},201.14,"<1","N/A","http://selleckchem.com/products/ampiroxicam.html","C20H21N3O7S","free base","CP 65703","CCOC(=O)OC(C)OC1=C(N(C)[S](=O)(=O)C2=C1C=CC=C2)C(=O)NC3=NC=CC=C3",1.718,8,1,8]
["S4018","Sennoside B","e6","L3800-17","in 10mM DMSO","N/A","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","PDGFR","Protein Tyrosine Kinase","Sennoside B, a kind of irritant laxative isolated from rhei rhizome, inhibits PDGF-stimulated cell proliferation., Sennoside B，一种从大黄根茎中分离得到的刺激性泻药，抑制PDGF刺激的细胞增殖。",862.74,"128-57-4",{"v":100,"d":"100.00"},115.91,"<1","N/A","http://selleckchem.com/products/sennoside-b.html","C42H38O20","Free Base","N/A","OCC1OC(OC2=CC=CC3=C2C(=O)C4=C(O)C=C(C=C4C3C5C6=C(C(=O)C7=C(O)C=C(C=C57)C(O)=O)C(=CC=C6)OC8OC(CO)C(O)C(O)C8O)C(O)=O)C(O)C(O)C1O",0.409,8,10,9]
["S4021","Tolcapone","h6","L3800-17","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","Marketed","COMT,Histone Methyltransferase,Transferase","Metabolism","Tolcapone (Ro 40-7592) is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with Ki of 30 nM.",273.24,"134308-13-7",{"v":55,"d":"55.00"},201.29,"<1","N/A","http://selleckchem.com/products/tolcapone.html","C14H11NO5","free base","Ro 40-7592","CC1=CC=C(C=C1)C(=O)C2=CC(=C(O)C(=C2)[N+]([O-])=O)O",{"v":3.13,"d":"3.130"},1,2,3]
["S4024","Homatropine Methylbromide","c7","L3800-17","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,Ph.Int_6th,BP2017","N/A","AChR","Neuronal Signaling","Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.",370.28,"80-49-9",{"v":74,"d":"74.00"},199.85,{"v":74,"d":"74.00"},199.85,"http://selleckchem.com/products/homatropine-methylbromide.html","C17H24NO3.Br","quaternary-N bromide salt","N/A","[Br-].C[N+]1(C)C2CCC1CC(C2)OC(=O)C(O)C3=CC=CC=C3",-2.076,2,1,4]
["S4025","Homatropine Bromide","d7","L3800-17","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","N/A","AChR","Neuronal Signaling","Homatropine Bromide is an muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.",356.25,"51-56-9",{"v":71,"d":"71.00"},{"v":199.3,"d":"199.30"},{"v":71,"d":"71.00"},{"v":199.3,"d":"199.30"},"http://selleckchem.com/products/homatropine-bromide.html","C16H21NO3.HBr","quaternary-N bromide salt","N/A","Br.CN1C2CCC1CC(C2)OC(=O)C(O)C3=CC=CC=C3",2.188,2,1,4]
["S4034","Diphemanil Methylsulfate","g7","L3800-17","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia","N/A","AChR","Neuronal Signaling","Diphemanil Methylsulfate is a quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors (mAchR).",389.51,"62-97-5",{"v":25,"d":"25.00"},64.18,{"v":28,"d":"28.00"},71.89,"http://selleckchem.com/products/diphemanil-methylsulfate.html","C20H24N.CH3O4S","Methylsulfate","N/A","CO[S]([O-])(=O)=O.C[N+]1(C)CC[C](CC1)=[C](C2=CC=CC=C2)C3=CC=CC=C3",0.038,1,0,3]
["S4040","Norethindrone","c8","L3800-17","in 10mM DMSO","FDA,DMF,NDC","CP2005,USP42-NF37,IP2010","Marketed","Others,0","Others","Norethindrone (Norethisterone) is a synthetic progestin, which mimic the actions of the endogenous ovarian hormone progesterone.",298.42,"68-22-4",{"v":60,"d":"60.00"},201.06,"<1","N/A","http://selleckchem.com/products/norethindrone-norethisterone.html","C20H26O2","free base","Norethisterone","CC12CCC3C(CCC4=CC(=O)CCC34)C1CCC2(O)C#C",4.315,1,0,0]
["S4043","Tetrahydrozoline HCl","f8","L3800-17","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ","N/A","Adrenergic Receptor","Neuronal Signaling","Tetrahydrozoline (Tetryzoline) HCl is an imidazoline derivative with alpha receptor agonist activity.",236.74,"522-48-5",{"v":12,"d":"12.00"},50.69,{"v":47,"d":"47.00"},198.53,"http://selleckchem.com/products/tetrahydrozoline-hcl.html","C13H16N2.HCl","hydrochloride","Tetryzoline HCl","Cl.C1CC(C2=NCCN2)C3=CC=CC=C3C1",2.567,1,1,1]
["S4046","Estradiol Cypionate","a9","L3800-17","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37,Ph.Int_6th","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Estradiol cypionate is the 17 β-cyclopentylpropinate ester of estradiol, which inhibits ET-1 synthesis via estrogen receptor.",396.56,"313-06-4",{"v":79,"d":"79.00"},199.21,"<1","N/A","http://selleckchem.com/products/estradiol-cypionate.html","C26H36O3","free base","N/A","CC12CCC3C(CCC4=CC(=CC=C34)O)C1CCC2OC(=O)CCC5CCCC5",6.589,2,1,5]
["S4050","Valganciclovir HCl","e9","L3800-17","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","Marketed","CMV","Microbiology","Valganciclovir HCl is a prodrug for ganciclovir with antiviral activity used to treat cytomegalovirus infections.",390.82,"175865-59-5",{"v":78,"d":"78.00"},199.58,{"v":78,"d":"78.00"},199.58,"http://selleckchem.com/products/valganciclovir-hcl.html","C14H22N6O5.HCl","Hydrochloride","N/A","Cl.CC(C)C(N)C(=O)OCC(CO)OCN1C=NC2C1N=C(N)NC2=O",-1.444,6,4,9]
["S4054","Spironolactone","h9","L3800-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8,KP Ⅹ,JP17,BP2017,IP2010","Marketed","Androgen Receptor","Endocrinology & Hormones","Spironolactone is a potent antagonist of the androgen receptor with IC50 of 77 nM.",416.57,"52-01-7",{"v":83,"d":"83.00"},199.25,"<1","N/A","http://selleckchem.com/products/spironolactone.html","C24H32O4S","free base","N/A","CC(=O)SC1CC2=CC(=O)CCC2(C)C3CCC4(C)C(CCC45CCC(=O)O5)C13",3.731,4,0,2]
["S4058","Ropivacaine HCl","c10","L3800-17","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1","Marketed","Sodium Channel","Transmembrane Transporters","Ropivacaine HCl (LEA-103) is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.",310.86,"98717-15-8",{"v":62,"d":"62.00"},199.45,{"v":46,"d":"46.00"},147.98,"http://selleckchem.com/products/ropivacaine-hcl.html","C17H26N2O.HCl","HCl","LEA-103 HCl","Cl.CCCN1CCCCC1C(=O)NC2=C(C)C=CC=C2C",4.236,1,1,4]
["S4059","Sodium Nitroprusside Dihydrate","d10","L3800-17","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia","Marketed","Others","Others","Sodium Nitroprusside  Dihydrate is a potent vasodilator working through releasing NO spontaneously in blood.",297.95,"13755-38-9",{"v":60,"d":"60.00"},201.38,{"v":60,"d":"60.00"},201.38,"http://selleckchem.com/products/sodium-nitroprusside-dihydrate.html","C5H4FeN6Na2O3","Dihydrate","N/A","[Na+].[Na+].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N",0.571,1,0,1]
["S4062","Ronidazole","g10","L3800-17","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Anti-infection","Microbiology","Ronidazole is an antiprotozoal agent.",200.15,"7681-76-7",{"v":40,"d":"40.00"},199.85,"<1","N/A","http://selleckchem.com/products/ronidazole.html","C6H8N4O4","free base","N/A","C[N]1C(=NC=C1[N+]([O-])=O)COC(N)=O",-0.301,3,1,4]
["S4070","Guanidine HCl","c11","L3800-17","in 10mM DMSO","FDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","N/A","Others","Others","Guanidine HCl (Aminoformamidine), the crystalline compound of strong alkalinity formed by the oxidation of guanine, is a normal product of protein metabolism and a protein denaturant.",95.53,"50-01-1",{"v":19,"d":"19.00"},198.89,{"v":19,"d":"19.00"},198.89,"http://selleckchem.com/products/guanidine-aminoformamidine-hcl.html","CH5N3.HCl","Hydrochloride","Aminoformamidine HCl","Cl.NC(N)=N",-0.606,0,2,0]
["S4073","Sodium 4-Aminosalicylate","f11","L3800-17","in 10mM DMSO","FDA,CFDA,DMF","Martindale the Extra Pharmacopoei,EP10.0,USP42-NF37,BP2017,IP2010","N/A","NF-κB","NF-κB","Sodium 4-Aminosalicylate is an antibiotic used to treat tuberculosis via NF-κB inhibition and free radical scavenging.",211.15,"6018-19-5",{"v":42,"d":"42.00"},198.91,{"v":42,"d":"42.00"},198.91,"http://selleckchem.com/products/aminosalicylate-sodium.html","C7H7NO3.2H2O.Na","Sodium Salt","N/A","[Na+].NC1=CC(=C(C=C1)C([O-])=O)O",-1.003,0,2,1]
["S4077","Mequinol","a2","L3800-18","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia","Marketed","Others","Others","Mequinol (4-Methoxyphenol) is a depigmentation agent.",124.14,"150-76-5",{"v":25,"d":"25.00"},201.39,{"v":25,"d":"25.00"},201.39,"http://selleckchem.com/products/mequinol.html","C7H8O2","free base","N/A","COC1=CC=C(O)C=C1",1.571,1,1,1]
["S4081","Sulfacetamide Sodium","e2","L3800-18","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,EP9.1,Ph.Int_6th,BP2017,USP39-NF34","Marketed","Anti-infection,Autophagy","Immunology & Inflammation","Sulfacetamide Sodium is an anti-biotic.",236.22,"127-56-0",{"v":19,"d":"19.00"},80.43,{"v":51,"d":"51.00"},{"v":215.9,"d":"215.90"},"http://selleckchem.com/products/sulfacetamide-sodium.html","C8H10N2O3S.Na","Sodium Salt","N/A","[Na+].CC(=O)[N-][S](=O)(=O)C1=CC=C(N)C=C1",-0.118,3,1,2]
["S4083","Vitamin A Acetate","g2","L3800-18","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia,USP39-NF34,BP2015,BP2013","N/A","Vitamin","Metabolism","Vitamin A Acetate (Retinyl, Retinol) is a group of unsaturated nutritional hydrocarbons, that includes retinol, retinal, retinoic acid, and several provitamin A carotenoids, among which beta-carotene is the most important.",328.49,"127-47-9",{"v":65,"d":"65.00"},197.88,"<1","N/A","http://selleckchem.com/products/vitamin-a-acetate.html","C22H32O2","free base","Retinyl (Retinol) Acetate","CC(=O)OC/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C",5.695,2,0,7]
["S4086","Loxapine Succinate","b3","L3800-18","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","Marketed","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Loxapine Succinate(NSC 759578) is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent.",{"v":445.9,"d":"445.90"},"27833-64-3",{"v":89,"d":"89.00"},{"v":199.6,"d":"199.60"},"<1","N/A","http://selleckchem.com/products/loxapine-succinate.html","C18H18ClN3O.C4H6O4","Succinate","NSC 759578","CN1CCN(CC1)C2=NC3=C(OC4=C2C=C(Cl)C=C4)C=CC=C3.OC(=O)CCC(O)=O",0.039,4,0,4]
["S4088","Flumethasone","c3","L3800-18","in 10mM DMSO","FDA,DMF","N/A","N/A","Glucocorticoid Receptor","Endocrinology & Hormones","Flumethasone (RS-2177, NSC-54702,Flumetasone) is a glucocorticoid receptor agonist, this complex binds to the nucleus causing a variety of genetic activation and repressions.",410.45,"2135-17-3",{"v":82,"d":"82.00"},199.78,"<1","N/A","http://selleckchem.com/products/flumethasone.html","C22H28F2O5","free base","RS-2177, NSC-54702,Flumetasone","CC1CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO",1.546,2,2,2]
["S4091","Ifenprodil Tartrate","f3","L3800-18","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17","Phase 2","NMDAR","Neuronal Signaling","Ifenprodil is an atypical noncompetitive antagonist at the NMDA receptor, it interacts with high affinity at a homogeneous population of NMDA receptors in neonatal rat forebrain with IC50 of 0.3 μM.",800.98,"23210-58-4",{"v":95,"d":"95.00"},{"v":118.6,"d":"118.60"},{"v":9,"d":"9.00"},11.24,"http://selleckchem.com/products/ifenprodil-tartrate.html","2(C21H27NO2).C4H6O6","Tartrate","N/A","CC(C(O)C1=CC=C(O)C=C1)N2CCC(CC2)CC3=CC=CC=C3.CC(C(O)C4=CC=C(O)C=C4)N5CCC(CC5)CC6=CC=CC=C6.OC(C(O)C(O)=O)C(O)=O",0.638,2,6,13]
["S4098","Halcinonide","b4","L3800-18","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37","N/A","Immunology & Inflammation related","Immunology & Inflammation","Halcinonide(SQ-18566) is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent.",454.96,"3093-35-4",{"v":90,"d":"90.00"},197.82,"<1","N/A","http://selleckchem.com/products/halcinonide.html","C24H32ClFO5","free base","SQ-18566","CC1(C)OC2CC3C4CCC5=CC(=O)CCC5(C)C4(F)C(O)CC3(C)C2(O1)C(=O)CCl",2.384,4,1,2]
["S4101","Voglibose","e4","L3800-18","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17","Marketed","Carbohydrate Metabolism","Metabolism","Voglibose (AO 128) is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various disorders caused by hyperglycemia.",267.28,"83480-29-9",{"v":74,"d":"74.00"},276.86,{"v":74,"d":"74.00"},276.86,"http://selleckchem.com/products/voglibose.html","C10H21NO7","free base","AO 128","OCC(CO)NC1CC(O)(CO)C(O)C(O)C1O",-4.083,0,7,5]
["S4105","Closantel Sodium","h4","L3800-18","in 10mM DMSO","N/A","EP9.7;BP2019","N/A","Bacterial","Microbiology","Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.",685.06,"61438-64-0",{"v":100,"d":"100.00"},145.97,"<1","N/A","http://selleckchem.com/products/closantel-sodium.html","C22H13Cl2I2N2O2.Na","Sodium Salt","N/A","[Na+].CC1=C(NC(=O)C2=CC(=CC(=C2[O-])I)I)C=C(Cl)C(=C1)C(C#N)C3=CC=C(Cl)C=C3",6.049,1,1,4]
["S4111","Dicloxacillin Sodium","d5","L3800-18","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","Phase 3","β-lactamase","Microbiology","Dicloxacillin Sodium (Veracillin, BRL1702) is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative aerobic and anaerobic bacteria.",510.32,"343-55-5",{"v":100,"d":"100.00"},195.96,{"v":100,"d":"100.00"},195.96,"http://selleckchem.com/products/dicloxacillin-sodium.html","C19H17Cl2N3O5S.H2O.Na","Sodium Salt","Veracillin, BRL1702","O.CC1=C(C(=O)NC2C3SC(C)(C)C(N3C2=O)C(=O)O[Na])C(=NO1)C4=C(Cl)C=CC=C4Cl",2.848,6,1,5]
["S4114","Triclabendazole","g5","L3800-18","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,BP2017","N/A","Microtubule Associated","Cytoskeletal Signaling","Triclabendazole (CGA-89317,tcbz) is a benzimidazole, it binds to tubulin impairing intracellular transport mechanisms and interferes with protein synthesis.",359.66,"68786-66-3",{"v":72,"d":"72.00"},200.19,"<1","N/A","http://selleckchem.com/products/triclabendazole.html","C14H9Cl3N2OS","free base","CGA-89317,tcbz","CSC1=NC2=C([NH]1)C=C(Cl)C(=C2)OC3=C(Cl)C(=CC=C3)Cl",5.982,2,1,3]
["S4116","Isovaleramide","h5","L3800-18","in 10mM DMSO","N/A","N/A","Phase 2","Dehydrogenase","Metabolism","Isovaleramide(3-Methylbutanamide) is an anticonvulsant molecule isolated from Valeriana pavonii, it inhibits the liver alcohol dehydrogenases.",101.15,"541-46-8",{"v":20,"d":"20.00"},197.73,"<1","N/A","http://selleckchem.com/products/isovaleramide.html","C5H11NO","free base","3-Methylbutanamide","CC(C)CC(N)=O",0.542,1,1,2]
["S4120","Sulconazole Nitrate","c6","L3800-18","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","N/A","Fungal","Microbiology","Sulconazole Nitrate(Exelderm,RS 44872) is an imidazole derivative with broad-spectrum antifungal activity.",460.76,"61318-91-0",{"v":92,"d":"92.00"},199.67,"<1","N/A","http://selleckchem.com/products/sulconazole-nitrate.html","C18H15Cl3N2S.HNO3","Nitrate","Exelderm,RS 44872","O[N+]([O-])=O.ClC1=CC=C(CSC(C[N]2C=CN=C2)C3=CC=C(Cl)C=C3Cl)C=C1",4.467,1,0,6]
["S4124","Tolazoline HCl","f6","L3800-18","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ","N/A","Adrenergic Receptor","Neuronal Signaling","Tolazoline(Imidaline hydrochloride,NSC35110 hydrochloride) is a non-selective competitive α-adrenergic receptor antagonist.",196.68,"59-97-2",{"v":39,"d":"39.00"},198.29,{"v":39,"d":"39.00"},198.29,"http://selleckchem.com/products/tolazoline-hcl.html","C10H12N2.HCl","Hydrochloride","Imidaline hydrochloride,NSC35110 hydrochloride","Cl.C1CN=C(CC2=CC=CC=C2)N1",1.533,1,1,2]
["S4135","Clorprenaline HCl","b7","L3800-18","in 10mM DMSO","CFDA","N/A","N/A","Adrenergic Receptor","GPCR & G Protein","Clorprenaline HCl (NSC 334693) is a β2-receptor agonist, it has a significant expansion of the bronchial effect.",250.16,"6933-90-0",{"v":50,"d":"50.00"},199.87,{"v":50,"d":"50.00"},199.87,"http://selleckchem.com/products/clorprenaline-hcl.html","C11H16ClNO.HCl","Hydrochloride","NSC 334693","Cl.CC(C)NCC(O)C1=CC=CC=C1Cl",2.629,0,2,4]
["S4139","Cyclizine 2HCl","e7","L3800-18","in 10mM DMSO","FDA,CFDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","N/A","Histamine Receptor","Neuronal Signaling","Cyclizine 2HCl is a piperazine derivative with Histamine H1 receptor antagonist activity.",{"v":339.3,"d":"339.30"},"5897-18-7",{"v":7,"d":"7.00"},20.63,{"v":68,"d":"68.00"},200.41,"http://selleckchem.com/products/cyclizine-2hcl.html","C18H22N2.2HCl","Hydrochloride","N/A","Cl.Cl.CN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3",4.237,0,0,3]
["S4147","Azithromycin Dihydrate","h7","L3800-18","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia","Marketed","Anti-infection","Microbiology","Azithromycin Dihydrate(CP-62993 dihydrate) is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin.",785.02,"117772-70-0",{"v":100,"d":"100.00"},127.39,{"v":10,"d":"10.00"},12.74,"http://selleckchem.com/products/azithromycin-dihydrate.html","C38H72N2O12.2H2O","free base","CP-62993 dihydrate","O.O.CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)CN(C)C(C)C(O)C1(C)O",1.663,7,3,7]
["S4152","Ethamsylate","d8","L3800-18","in 10mM DMSO","CFDA","N/A","Phase 2","Prostaglandin Receptor","GPCR & G Protein","Ethamsylate (Etamsylate) is a haemostatic drug, which inhibits biosynthesis and action of prostaglandins, and increases capillary endothelial resistance as and platelet adhesion.",263.31,"2624-44-4",{"v":53,"d":"53.00"},201.28,{"v":53,"d":"53.00"},201.28,"http://selleckchem.com/products/ethamsylate.html","C6H6O5S.C4H11N","Diethylamine","Etamsylate","CCNCC.OC1=CC=C(O)C(=C1)[S](O)(=O)=O",{"v":1.16,"d":"1.160"},0,3,3]
["S4160","Penicillin G Sodium","g8","L3800-18","in 10mM DMSO","DMF,NDC,FDA","KP Ⅹ,EP9.0,IP2010","Phase 4","Antibiotics,Antibiotics for Mammalian Cell Culture,Antibiotics for Plant Cell Culture","Microbiology","Penicillin G Sodium (Benzylpenicillin) is a β-lactam antibiotic produced by Penicillin spp.",356.37,"69-57-8",{"v":71,"d":"71.00"},199.23,{"v":71,"d":"71.00"},199.23,"http://selleckchem.com/products/benzylpenicillin-sodium.html","C16H18N2O4S.Na","Sodium Salt","Benzylpenicillin Sodium","[Na+].CC1(C)SC2C(NC(=O)CC3=CC=CC=C3)C(=O)N2C1C([O-])=O",{"v":-0.35,"d":"-0.350"},2,1,4]
["S4161","Benzoic Acid","h8","L3800-18","in 10mM DMSO","DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,CP2005,EP7.0,Ph.Int_6th,JP17,BP2017,USP39-NF34,IP2010","N/A","Others","Microbiology","Benzoic acid (FEMA 2131) is a colorless crystalline solid and a simple aromatic carboxylic acid, used as a food preservative.",122.12,"65-85-0",{"v":24,"d":"24.00"},196.53,"<1","N/A","http://selleckchem.com/products/benzoic-acid.html","C7H6O2","free base","FEMA 2131","OC(=O)C1=CC=CC=C1",1.459,1,0,1]
["S4164","Doxofylline","c9","L3800-18","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,IP2010","Marketed","PDE","Metabolism","Doxofylline (Doxophylline) is a phosphodiesterase inhibitor and a xanthine derivative drug for asthma.",266.25,"69975-86-6",{"v":53,"d":"53.00"},199.06,{"v":24,"d":"24.00"},90.14,"http://selleckchem.com/products/doxofylline.html","C11H14N4O4","free base","Doxophylline","CN1C(=O)N(C)C2=C([N](CC3OCCO3)C=N2)C1=O",-0.344,5,0,2]
["S4167","Cyromazine","f9","L3800-18","in 10mM DMSO","N/A","USP42-NF37;Martindale:The Extra Pharmacopoeia","N/A","Parasite","Microbiology","Cyromazine(Cyromazin,CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide.",166.18,"66215-27-8",{"v":33,"d":"33.00"},198.58,{"v":1,"d":"1.00"},6.02,"http://selleckchem.com/products/cyromazine.html","C6H10N6","free base","Cyromazin,CGA-72662","NC1=NC(=NC(=N1)N)NC2CC2",0.313,3,3,2]
["S4172","Cetylpyridinium Chloride","b10","L3800-18","in 10mM DMSO","DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","Phase 2","Anti-infection","Microbiology","Cetylpyridinium chloride(CPC) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.",339.99,"123-03-5",{"v":68,"d":"68.00"},200.01,{"v":68,"d":"68.00"},200.01,"http://selleckchem.com/products/cetylpyridinium-chloride.html","C21H38N.Cl","Chloride","CPC","[Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1",5.563,0,0,15]
["S4175","Sulfaguanidine","d10","L3800-18","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","N/A","Anti-infection","Microbiology","Sulfaguanidine is a sulfonamide used as an anti-infective agent.",214.24,"57-67-0",{"v":43,"d":"43.00"},200.71,"<1","N/A","http://selleckchem.com/products/sulfaguanidine.html","C7H10N4O2S","free base","N/A","NC(=N)N[S](=O)(=O)C1=CC=C(N)C=C1",-0.377,2,3,3]
["S4179","Mezlocillin Sodium","h10","L3800-18","in 10mM DMSO","FDA,CFDA","Martindale:The Extra Pharmacopoeia,USP39-NF34","N/A","Antibiotics,Bacterial","Microbiology","Mezlocillin sodium is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms.",561.56,"42057-22-7",{"v":100,"d":"100.00"},178.08,{"v":100,"d":"100.00"},178.08,"http://selleckchem.com/products/mezlocillin-sodium.html","C21H25N5O8S2.Na","Sodium Salt","N/A","[Na+].CC1(C)SC2C(NC(=O)C(NC(=O)N3CCN(C3=O)[S](C)(=O)=O)C4=CC=CC=C4)C(=O)N2C1C([O-])=O",{"v":-1.69,"d":"-1.690"},6,2,6]
["S4184","Penciclovir","c11","L3800-18","in 10mM DMSO","FDA,CFDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia","Marketed","Antiviral","Microbiology","Penciclovir (BRL-39123, VSA 671,NSC-759624) is a purine acyclic nucleoside analogue with potent antiviral activity.",253.26,"39809-25-1",{"v":34,"d":"34.00"},134.25,{"v":1,"d":"1.00"},3.95,"http://selleckchem.com/products/penciclovir.html","C10H15N5O3","free base","BRL-39123, VSA 671,NSC-759624","NC1=NC(=O)C2=C(N1)[N](CCC(CO)CO)C=N2",-1.533,3,4,5]
["S4187","Salicylanilide","f11","L3800-18","in 10mM DMSO","DMF,CFDA","N/A","N/A","Fungal,Integrase,Reverse Transcriptase","Microbiology","Salicylanilides (WR10019,2-Hydroxybenzanilide) are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities.",213.23,"87-17-2",{"v":43,"d":"43.00"},201.66,"<1","N/A","http://selleckchem.com/products/salicylanilide.html","C13H11NO2","free base","WR10019,2-Hydroxybenzanilide","OC1=CC=CC=C1C(=O)NC2=CC=CC=C2",2.372,1,2,2]
["S4188","Sasapyrine","g11","L3800-18","in 10mM DMSO","DMF,CFDA,NDC","N/A","N/A","Immunology & Inflammation related","Immunology & Inflammation","Sasapyrine (Salsalate, NSC-49171) is a nonsteroidal oral anti-inflammatory agent.",258.23,"552-94-3",{"v":52,"d":"52.00"},201.37,"<1","N/A","http://selleckchem.com/products/sasapyrine.html","C14H10O5","free base","NSC-49171,Salsalate","OC(=O)C1=CC=CC=C1OC(=O)C2=CC=CC=C2O",2.649,3,1,4]
["S4191","Betamipron","b2","L3800-19","in 10mM DMSO","N/A","JP17;Martindale:The Extra Pharmacopoeia","Marketed","Anti-infection","Microbiology","Betamipron (CS-443,N-Benzoyl-β-alanine) is a chemical compound which is used together with panipenem to inhibit panipenem uptake into the renal tubule and prevent nephrotoxicity.",{"v":193.2,"d":"193.20"},"3440-28-6",{"v":39,"d":"39.00"},201.86,"<1","N/A","http://selleckchem.com/products/betamipron.html","C10H11NO3","free base","CS-443,N-Benzoyl-β-alanine","OC(=O)CCNC(=O)C1=CC=CC=C1",0.767,2,1,4]
["S4196","Ethacridine lactate monohydrate","e2","L3800-19","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017","N/A","Anti-infection","Microbiology","Ethacridine lactate monohydrate(Acrinol monohydrat) is an aromatic organic compound based on acridine used as an antiseptic agent.",361.39,"6402-23-9",{"v":72,"d":"72.00"},199.23,{"v":5,"d":"5.00"},13.84,"http://selleckchem.com/products/ethacridine-lactate-monohydrate.html","C15H15N3O.C3H6O3.H2O","Lactate","Acrinol monohydrat","O.CCOC1=CC2=C(N)C3=CC=C(N)C=C3N=C2C=C1.CC(O)C(O)=O",1.592,3,3,3]
["S4202","Verapamil (CP-16533-1) HCl","a3","L3800-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","Marketed","Calcium Channel,P450 (e.g. CYP17),P-gp","Transmembrane Transporters","Verapamil HCl (CP-16533-1,(±)-Verapamil hydrochloride) is an L-type calcium channel blocker that is a class IV anti-arrhythmia agent. Verapamil inhibits both permeability-glycoprotein (P-gp) and CYP3A4.",491.06,"152-11-4",{"v":98,"d":"98.00"},199.57,{"v":50,"d":"50.00"},101.82,"http://selleckchem.com/products/verapami-hcl.html","C27H38N2O4.HCl","Hydrochloride","(±)-Verapamil hydrochloride","Cl.COC1=CC=C(CCN(C)CCCC(C#N)(C(C)C)C2=CC=C(OC)C(=C2)OC)C=C1OC",5.916,4,0,13]
["S4206","Cysteamine HCl","d3","L3800-19","in 10mM DMSO","FDA,DMF,NDC,PMDA","N/A","Marketed","Antioxidant","Metabolism","Cysteamine HCl(Mercaptamine) is an autophagy-stimulatory proteostasis regulator. Cysteamine can be used for the treatment of nephropathic cystinosis and an antioxidant.",113.61,"156-57-0",{"v":23,"d":"23.00"},202.45,{"v":23,"d":"23.00"},202.45,"http://selleckchem.com/products/cysteamine-hcl.html","C2H7NS.HCl","Hydrochloride","Mercaptamine","Cl.NCCS",0.166,0,1,1]
["S4213","Dirithromycin","h3","L3800-19","in 10mM DMSO","FDA,CFDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,BP2017","Marketed","Antibiotics,Bacterial","Microbiology","Dirithromycin (LY-237216, ASE 136,Dynabac) is a macrolide glycopeptide antibiotic by binding to the 50S subunit of the 70S bacterial ribosome to inhibit the translocation of peptides.",835.07,"62013-04-1",{"v":11,"d":"11.00"},13.17,"<1","N/A","http://selleckchem.com/products/dirithromycin.html","C42H78N2O14","free base","LY-237216, ASE 136,Dynabac","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)C4NC(COCCOC)OC(C4C)C1(C)O",1.869,10,3,12]
["S4217","Liothyronine Sodium","c4","L3800-19","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,JP17,BP2016","Phase 2","THR","Metabolism","Liothyronine Sodium(Cytomel) is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis.",672.96,"55-06-1",{"v":100,"d":"100.00"},{"v":148.6,"d":"148.60"},"<1","N/A","http://selleckchem.com/products/liothyronine-sodium.html","C15H12I3NO4.Na","sodium","Cytomel","[Na+].NC(CC1=CC(=C(OC2=CC=C(O)C(=C2)I)C(=C1)I)I)C([O-])=O",2.452,1,2,5]
["S4222","Piperacillin Sodium","f4","L3800-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,JP17,BP2017","Marketed","Antibiotics","Microbiology","Piperacillin (CL227193,Pipracil) is a semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections.",539.54,"59703-84-3",{"v":100,"d":"100.00"},185.34,{"v":100,"d":"100.00"},185.34,"http://selleckchem.com/products/piperacillin-sodium.html","C23H27N5O7S.Na","Sodium Salt","CL227193,Pipracil","[Na+].CCN1CCN(C(=O)NC(C(=O)NC2C3SC(C)(C)C(N3C2=O)C([O-])=O)C4=CC=CC=C4)C(=O)C1=O",-1.558,5,2,6]
["S4223","Mevastatin","g4","L3800-19","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia","N/A","HMG-CoA Reductase","Metabolism","Mevastatin (ML-236B,Compactin) is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 times greater than the HMG-CoA substrate itself.",390.51,"73573-88-3",{"v":78,"d":"78.00"},199.74,"<1","N/A","http://selleckchem.com/products/mevastatin.html","C23H34O5","free base","ML-236B,Compactin","CCC(C)C(=O)OC1CCC=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C12",3.966,4,1,7]
["S4227","Fidaxomicin","b5","L3800-19","in 10mM DMSO","FDA,DMF,NDC,PMDA,EMA","N/A","Marketed","DNA/RNA Synthesis","DNA Damage/DNA Repair","Fidaxomicin (OPT-80, PAR-101,Dificid) is a narrow spectrum macrocyclic antibiotic that inhibits RNA polymerase sigma subunit.",1058.04,"873857-62-6",{"v":100,"d":"100.00"},94.51,"<1","N/A","http://selleckchem.com/products/fidaxomicin.html","C52H74Cl2O18","free base","OPT-80, PAR-101,Dificid","CCC1\\C=C(C)/C(O)C\\C=C\\C=C(COC2OC(C)C(OC(=O)C3=C(CC)C(=C(O)C(=C3O)Cl)Cl)C(O)C2OC)\\C(=O)OC(C\\C=C(C)\\C=C(C)\\C1OC4OC(C)(C)C(OC(=O)C(C)C)C(O)C4O)C(C)O",7.774,11,7,15]
["S4230","Oxaprozin","e5","L3800-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,KP Ⅹ,JP17","N/A","COX","Metabolism","Oxaprozin (WY-21743,nsc 310839) is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID) used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis.",293.32,"21256-18-8",{"v":59,"d":"59.00"},201.15,"<1","N/A","http://selleckchem.com/products/oxaprozin.html","C18H15NO3","free base","WY-21743,nsc 310839","OC(=O)CCC1=NC(=C(O1)C2=CC=CC=C2)C3=CC=CC=C3",{"v":3.59,"d":"3.590"},3,0,5]
["S4238","Cepharanthine","a6","L3800-19","in 10mM DMSO","PMDA","N/A","N/A","TNF-alpha","Apoptosis","Cepharanthine (NSC-623442) is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production.",606.71,"481-49-2",{"v":100,"d":"100.00"},164.82,"<1","N/A","http://selleckchem.com/products/cepharanthine.html","C37H38N2O6","free base","NSC-623442","COC1=C2OC3=CC=C(CC4N(C)CCC5=C4C(=C6OCOC6=C5)OC7=C(OC)C=C8CCN(C)C(CC(=C2)C=C1)C8=C7)C=C3",7.019,6,0,2]
["S4242","Cetrimonium Bromide (CTAB)","d6","L3800-19","in 10mM DMSO","N/A","USP42-NF37;Martindale:The Extra Pharmacopoeia","N/A","Anti-infection","Microbiology","Cetrimonium Bromide (CTAB) is a known component of the broad-spectrum antiseptic cetrimide, which is a mixture of different quaternary ammonium salts.",364.45,"57-09-0",{"v":5,"d":"5.00"},13.72,{"v":100,"d":"100.00"},274.39,"http://selleckchem.com/products/cetrimonium-bromide.html","C19H42N.Br","free base","N/A","[Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C",{"v":3.35,"d":"3.350"},0,0,15]
["S4247","Prucalopride Succinate","h6","L3800-19","in 10mM DMSO","FDA,CFDA,HMA","N/A","Marketed","5-HT Receptor","Neuronal Signaling","Prucalopride(R-108512) is a selective, high affinity 5-HT4 receptor agonist. The Ki values of prucalopride for human 5-HT(4a) and 5-HT(4b) receptor are 2.5 nM and 8 nM, respectively.",485.96,"179474-85-2",{"v":97,"d":"97.00"},{"v":199.6,"d":"199.60"},{"v":97,"d":"97.00"},{"v":199.6,"d":"199.60"},"http://selleckchem.com/products/prucalopride-succinat.html","C18H26ClN3O3.C4H6O4","Succinat","R-108512","COCCCN1CCC(CC1)NC(=O)C2=C3OCCC3=C(N)C(=C2)Cl.OC(=O)CCC(O)=O",-2.338,5,2,9]
["S4250","Sulfamethoxypyridazine","c7","L3800-19","in 10mM DMSO","N/A","EP9.2;Ph.Int_6th;Martindale:The Extra Pharmacopoeia","N/A","Anti-infection","Microbiology","Sulfamethoxypyridazine (CL 13494) is a long-acting sulfonamide for treatment of Dermatitis herpetiformis.",{"v":280.3,"d":"280.30"},"80-35-3",{"v":56,"d":"56.00"},199.79,"<1","N/A","http://selleckchem.com/products/sulfamethoxypyridazine.html","C11H12N4O3S","free base","CL 13494","COC1=NN=C(N[S](=O)(=O)C2=CC=C(N)C=C2)C=C1",1.014,5,2,4]
["S4256","Buspirone HCl","f7","L3800-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,BP2017,IP2010","Phase 2","5-HT Receptor","Neuronal Signaling","Buspirone(Buspirone hydrochloride) is a serotonergic (5HT(1A) receptor agonist) anxiolytic drug with some D(2) dopaminergic effect, used for anxiety disorders.",421.96,"33386-08-2",{"v":84,"d":"84.00"},199.07,{"v":84,"d":"84.00"},199.07,"http://selleckchem.com/products/buspirone-hcl.html","C21H31N5O2.HCl","Hydrochloride","Buspirone hydrochloride","Cl.O=C1CC2(CCCC2)CC(=O)N1CCCCN3CCN(CC3)C4=NC=CC=N4",2.403,4,0,6]
["S4257","Alizapride HCl","g7","L3800-19","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","N/A","Dopamine Receptor","Neuronal Signaling","Alizapride HCl(Alizapride hydrochloride) is a dopamine receptor antagonist used for the theropy of nausea and vomiting.",351.83,"59338-87-3",{"v":42,"d":"42.00"},119.38,{"v":70,"d":"70.00"},198.96,"http://selleckchem.com/products/alizapride-hcl.html","C16H21N5O2.HCl","hydrochloride","Alizapride hydrochloride","Cl.COC1=CC2=C(C=C1C(=O)NCC3CCCN3CC=C)N=N[NH]2",2.253,4,2,6]
["S4259","Vilazodone HCl","a8","L3800-19","in 10mM DMSO","FDA,NDC,DMF","N/A","Marketed","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Vilazodone HCl(EMD68843,SB659746A) is a selective serotonin reuptake inhibitor (SSRI) and  a partial agonist of 5-HT1A receptors, used for the treatment of major depressive disorder.",477.99,"163521-08-2",{"v":96,"d":"96.00"},200.84,"<1","N/A","http://selleckchem.com/products/vilazodone-hcl.html","C26H27N5O2.HCl","Hydrochloride","EMD68843,SB659746A","Cl.NC(=O)C1=CC2=C(O1)C=CC(=C2)N3CCN(CCCCC4=C[NH]C5=C4C=C(C=C5)C#N)CC3",4.918,2,2,7]
["S4265","Nicaraven","e8","L3800-19","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Nicaraven is a hydroxyl radical scavenger with antivasospastic and neuroprotective effects.",284.31,"79455-30-4",{"v":57,"d":"57.00"},200.49,{"v":57,"d":"57.00"},200.49,"http://selleckchem.com/products/nicaraven.html","C15H16N4O2","free base","N/A","CC(CNC(=O)C1=CN=CC=C1)NC(=O)C2=CN=CC=C2",-0.029,4,2,5]
["S4268","Flufenamic acid","h8","L3800-19","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017","Phase 2","Immunology & Inflammation related","Immunology & Inflammation","Flufenamic Acid is an anti-inflammatory agent, and also acts as an ion channel modulator.",281.23,"530-78-9",{"v":56,"d":"56.00"},199.13,"<1","N/A","http://selleckchem.com/products/flufenamic-acid.html","C14H10F3NO2","free base","N/A","OC(=O)C1=CC=CC=C1NC2=CC=CC(=C2)C(F)(F)F",3.952,1,1,4]
["S4274","Rotigotine","c9","L3800-19","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,EP9.6","Marketed","Dopamine Receptor","Neuronal Signaling","Rotigotine(N-0923) is a dopamine receptor agonist, used in the treatment of Parkinson's disease and restless legs syndrome.",315.47,"99755-59-6",{"v":63,"d":"63.00"},{"v":199.7,"d":"199.70"},"<1","N/A","http://selleckchem.com/products/rotigotine.html","C19H25NOS","free base","N-0923","CCCN(CCC1=CC=CS1)C2CCC3=C(C2)C=CC=C3O",4.986,0,1,6]
["S4280","Meclofenoxate (Centrophenoxine) HCl","g9","L3800-19","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17","N/A","Transferase","Metabolism","Meclofenoxate (Centrophenoxine) HCl is an anti-aging drug used to treat the symptoms of senile dementia and Alzheimer's disease, and also inhibits the activity of cholinephosphotransferase.",294.17,"3685-84-5",{"v":58,"d":"58.00"},197.16,{"v":58,"d":"58.00"},197.16,"http://selleckchem.com/products/meclofenoxate-centrophenoxine-hci.html","C12H17Cl2NO3","Hydrochloride","Centrophenoxine","Cl.CN(C)CCOC(=O)COC1=CC=C(Cl)C=C1",2.705,3,0,7]
["S4283","Cyclobenzaprine HCl","b10","L3800-19","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","Phase 3","5-HT Receptor","Neuronal Signaling","Cyclobenzaprine HCl(Cyclobenzaprine hydrochloride) is a muscle relaxant by blocking pain sensations, used for the treatment of muscle spasms; A 5-HT2 receptor antagonist.",311.85,"6202-23-9",{"v":62,"d":"62.00"},198.81,{"v":62,"d":"62.00"},198.81,"http://selleckchem.com/products/cyclobenzaprine-hci.html","C20H22ClN","Hydrochloride","Cyclobenzaprine hydrochloride","Cl.CN(C)CCC=C1C2=C(C=CC=C2)C=CC3=C1C=CC=C3",4.709,0,0,3]
["S4286","Anidulafungin (LY303366)","e10","L3800-19","in 10mM DMSO","FDA,DMF,EMA,NDC,HMA","Martindale:The Extra Pharmacopoeia","Marketed","Fungal","Microbiology","Anidulafungin (LY303366), an echinocandin derivative, inhibits glucan synthase activity, used as an antifungal drug.",1140.24,"166663-25-8",{"v":100,"d":"100.00"},{"v":87.7,"d":"87.70"},"<1","N/A","http://selleckchem.com/products/anidulafungin-ly303366.html","C58H73N7O17","free base","LY303366","CCCCCOC1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)NC4CC(O)C(O)NC(=O)C5C(O)C(C)CN5C(=O)C(NC(=O)C(NC(=O)C6CC(O)CN6C(=O)C(NC4=O)C(C)O)C(O)C(O)C7=CC=C(O)C=C7)C(C)O",-0.358,8,14,14]
["S4288","Chloroambucil","f10","L3800-19","in 10mM DMSO","FDA,DMF,NDC","N/A","N/A","DNA/RNA Synthesis","DNA Damage/DNA Repair","Chloroambucil (Chlorambucil,CB-1348,WR-139013) is a nitrogen mustard alkylating agent, used in the treatment of chronic lymphocytic leukemia.",304.21,"305-03-3",{"v":60,"d":"60.00"},197.23,"<1","N/A","http://selleckchem.com/products/chloroambucil.html","C14H19Cl2NO2","free base","Chlorambucil,CB-1348,WR-139013","OC(=O)CCCC1=CC=C(C=C1)N(CCCl)CCCl",3.899,1,0,9]
["S4292","Diphenidol HCl","a11","L3800-19","in 10mM DMSO","FDA,CFDA,DMF","N/A","Phase 4","AChR","Neuronal Signaling","Diphenidol HCl(Diphenidol hydrochloride) is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02, respectively, used in the treatment of vomiting and vertigo.",345.91,"3254-89-5",{"v":69,"d":"69.00"},199.47,{"v":13,"d":"13.00"},37.58,"http://selleckchem.com/products/diphenidol-hcl.html","C21H28ClNO","Hydrochloride","Diphenidol hydrochloride","Cl.OC(CCCN1CCCCC1)(C2=CC=CC=C2)C3=CC=CC=C3",4.774,0,0,6]
["S4296","Salmeterol Xinafoate","e11","L3800-19","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","Marketed","Adrenergic Receptor","GPCR & G Protein","Salmeterol Xinafoate(GR 33343X xinafoate,Salmetedur) is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms.",603.75,"94749-08-3",{"v":100,"d":"100.00"},165.63,"<1","N/A","http://selleckchem.com/products/salmeterol-xinafoate.html","C36H45NO7","xinafoate","GR 33343X xinafoate,Salmetedur","OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC2=CC=CC=C2.OC(=O)C3=C(O)C4=CC=CC=C4C=C3",3.673,2,5,17]
["S4301","(R)-(+)-Atenolol HCl","h11","L3800-19","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","Marketed","Adrenergic Receptor","Others","(R)-(+)-Atenolol binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists.",266.34,"56715-13-0",{"v":53,"d":"53.00"},198.99,{"v":18,"d":"18.00"},67.58,"http://selleckchem.com/products/atenolol.html","C9H16ClNO2","Hydrochloride","N/A","Cl.CC(=O)OC1CN2CCC1CC2",0.939,2,0,2]
["S4305","Anisotropine Methylbromide","c2","L3800-20","in 10mM DMSO","FDA,DMF","N/A","N/A","Others","Others","Anisotropine Methylbromide is a quaternary ammonium compound, used as treatment adjunct in peptic ulcer.",362.35,"80-50-2",{"v":25,"d":"25.00"},68.99,{"v":72,"d":"72.00"},{"v":198.7,"d":"198.70"},"http://www.selleckchem.com/products/anisotropine-methylbromide.html","C17H32BrNO2","methylbromide","N/A","[Br-].CCCC(CCC)C(=O)OC1CC2CCC(C1)[N+]2(C)C",-0.169,2,0,7]
["S4312","Carbadox","g2","L3800-20","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Carbadox is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease.",262.22,"6804-07-5",{"v":8,"d":"8.00"},30.51,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/carbadox.html","C11H10N4O4","Free Base","N/A","COC(=O)N/N=C/C1=[N+]([O-])C2=C(C=CC=C2)[N+](=C1)[O-]",-0.134,3,1,3]
["S4322","Disopyramide Phosphate","b3","L3800-20","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","N/A","Others","Others","Disopyramide (DISO) is a widely used Class 1a antiarrhythmic agent that is employed in the treatment of ventricular and supraventricular arrhythmias.",437.47,"22059-60-5",{"v":12,"d":"12.00"},27.43,{"v":87,"d":"87.00"},198.87,"http://www.selleckchem.com/products/disopyramide-phosphate.html","C21H32N3O5P","phosphate","N/A","CC(C)N(CCC(C(N)=O)(C1=CC=CC=C1)C2=NC=CC=C2)C(C)C.O[P](O)(O)=O",2.949,2,1,8]
["S4331","Meclocycline Sulfosalicylate","e3","L3800-20","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ","N/A","Others","Others","Meclocycline is a tetracycline antibiotic. Meclocycline sulfosalicylate prevents bacterial protein synthesis through 30S ribosome-mediated chain elongation and blocks amino-acyl tRNA A-site binding.",695.05,"73816-42-9",{"v":100,"d":"100.00"},143.87,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/meclocycline-sulfosalicylate.html","C22H21ClN2O8.C7H6O6S","sulfosalicylate","N/A","CN(C)C1C2C(O)C3C(=C)C4=C(C(=CC=C4Cl)O)C(=O)C3=C(O)C2(O)C(=O)C(=C1O)C(N)=O.OC(=O)C5=C(O)C=CC(=C5)[S](O)(=O)=O",-2.767,4,6,4]
["S4332","Medrysone","f3","L3800-20","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","N/A",344.49,"2668-66-8",{"v":69,"d":"69.00"},{"v":200.3,"d":"200.30"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/medrysone.html","C22H32O3","Free Base","N/A","CC1CC2C3CCC(C(C)=O)C3(C)CC(O)C2C4(C)CCC(=O)C=C14",2.942,2,1,1]
["S4336","Metaraminol Bitartrate","a4","L3800-20","in 10mM DMSO","FDA,CFDA,HMA","USP42-NF37","Phase 3","Others","Others","N/A",317.29,"33402-03-8",{"v":63,"d":"63.00"},198.56,{"v":63,"d":"63.00"},198.56,"http://www.selleckchem.com/products/metaraminol-bitartrate.html","C13H19NO8","bitartrate","Metaradrine Bitartrate","CC(N)C(O)C1=CC=CC(=C1)O.OC(C(O)C(O)=O)C(O)=O",-3.582,2,5,5]
["S4344","Oxprenolol HCl","e4","L3800-20","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,IP2010","N/A","Adrenergic Receptor","Others","Oxprenolol is a non-selective beta blocker with some intrinsic sympathomimetic activity.",301.81,"6452-73-9",{"v":60,"d":"60.00"},{"v":198.8,"d":"198.80"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/oxprenolol-hcl.html","C15H23NO3.HCl","hydrochloride","N/A","Cl.CC(C)NCC(O)COC1=CC=CC=C1OCC=C",2.614,2,2,9]
["S4351","Ractopamine HCl","h4","L3800-20","in 10mM DMSO","N/A","USP42-NF37","N/A","Others","Others","Ractopamine HCl (RAC), a beta-agonist with established nutrient partitioning capabilities, promotes skeletal muscle accretion at the expense of fat deposition.",337.84,"90274-24-1",{"v":67,"d":"67.00"},198.32,{"v":67,"d":"67.00"},198.32,"http://www.selleckchem.com/products/ractopamine-hcl.html","C18H24ClNO3","hydrochloride","N/A","Cl.CC(CCC1=CC=C(O)C=C1)NCC(O)C2=CC=C(O)C=C2",3.493,0,4,7]
["S4354","Thiostrepton","b5","L3800-20","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","N/A","Others","Others","Thiostrepton (Alaninamide, Bryamycin, Thiactin) is a natural cyclic oligopeptide antibiotic, derived from several strains of strepromycetes.",1664.89,"1393-48-2",{"v":100,"d":"100.00"},60.06,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/thiostrepton.html","C72H85N19O18S5","Free Base","Alaninamide, Bryamycin, Thiactin","CCC(C)C1NC2C=CC3=C(C=C(N=C3C2O)C(=O)OC(C)C4NC(=O)C5=CSC(=N5)C(NC(=O)C6CSC(=N6)\\C(NC(=O)C(NC(=O)C7=CSC(=N7)C8(CCC(=NC8C9=CSC4=N9)C%10=NC(=CS%10)C(=O)NC(=C)C(=O)NC(=C)C(N)=O)NC(=O)C(C)NC(=O)C(=C)NC(=O)C(C)NC1=O)C(C)O)=C\\C)C(C)(O)C(C)O)C(C)O",-1.361,20,16,12]
["S4362","Glafenine HCl","f5","L3800-20","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Glafenine is an anthranilic acid derivative with analgesic properties, which has been used previously in the treatment of pain.",409.26,"65513-72-6",{"v":81,"d":"81.00"},197.92,{"v":7,"d":"7.00"},{"v":17.1,"d":"17.10"},"http://www.selleckchem.com/products/glafenine-hcl.html","C19H18Cl2N2O4","hydrochloride","N/A","Cl.OCC(O)COC(=O)C1=CC=CC=C1NC2=CC=NC3=CC(=CC=C23)Cl",3.418,3,3,7]
["S4367","Suxibuzone","a6","L3800-20","in 10mM DMSO","N/A","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Suxibuzone is a prodrug of the non steroidal anti inflammatory drug phenylbutazone, and is commonly used in horses.",438.47,"27470-51-5",{"v":88,"d":"88.00"},{"v":200.7,"d":"200.70"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/suxibuzone.html","C24H26N2O6","Free Base","N/A","CCCCC1(COC(=O)CCC(O)=O)C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3",3.504,5,0,11]
["S4368","Carbenoxolone Sodium","b6","L3800-20","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,BP2015,IP2010","N/A","Others","Others","Carbenoxolone, a synthetic derivative of glycyrrhetinic acid, is also used as a blocker of the enzyme 11β-hydroxysteroid dehydrogenase (11β-HSD), of pannexon membrane channels (comprising 6 subunits of pannexin) and the related innexon channels.",614.72,"7421-40-1",{"v":23,"d":"23.00"},37.42,{"v":100,"d":"100.00"},162.68,"http://www.selleckchem.com/products/carbenoxolone-sodium.html","C34H48Na2O7","disodiuM","N/A","[Na+].[Na+].CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C([O-])=O)OC(=O)CCC([O-])=O",2.933,3,0,6]
["S4376","Aceclidine HCl","e6","L3800-20","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","Phase 2","Others","Others","Aceclidine is a parasympathomimetic miotic agent used to decreases intraocular pressure.",205.68,"6109-70-2",{"v":41,"d":"41.00"},199.34,{"v":41,"d":"41.00"},199.34,"http://www.selleckchem.com/products/aceclidine-hcl.html","C9H16ClNO2","hydrochloride","N/A","Cl.CC(=O)OC1CN2CCC1CC2",0.939,2,0,2]
["S4382","Pyrilamine Maleate","h6","L3800-20","in 10mM DMSO","FDA,NDC,DMF","USP42-NF37,IP2010","N/A","Histamine Receptor","Neuronal Signaling","Pyrilamine Maleate (Mepyramine)is a histamine H1 receptor inverse agonist, it binds to a G protein-coupled form of the receptor and promotes a G protein-coupled inactive state of the H1 receptor that interferes with the Gq/11-mediated signaling.",401.46,"59-33-6",{"v":80,"d":"80.00"},199.27,{"v":80,"d":"80.00"},199.27,"https://www.selleckchem.com/products/pyrilamine-maleate.html","C17H23N3O1.C4H4O4","maleate","Mepyramine Maleate","COC1=CC=C(CN(CCN(C)C)C2=CC=CC=N2)C=C1.OC(=O)\\C=C/C(O)=O",{"v":0.09,"d":"0.090"},4,0,9]
["S4389","Bephenium Hydroxynaphthoate","d7","L3800-20","in 10mM DMSO","N/A","Ph.Int_6th;Martindale:The Extra Pharmacopoeia","N/A","AChR,Parasite","Neuronal Signaling","Bephenium(NSC 759245) is an activator of B-type Acetylcholine receptor (AChR). Bephenium selectively activates the Hco-L-AChR1 subtype made of Hco-UNC-29.1, Hco-UNC-38, Hco-UNC-63, Hco-ACR-8 subunits. Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis.",443.53,"3818-50-6",{"v":88,"d":"88.00"},198.41,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/bephenium-hydroxynaphthoate.html","C28H29NO4","hydroxynaphthoa","NSC 759245","C[N+](C)(CCOC1=CC=CC=C1)CC2=CC=CC=C2.OC3=C(C=C4C=CC=CC4=C3)C([O-])=O",2.833,1,1,7]
["S4394","Clofoctol","g7","L3800-20","in 10mM DMSO","marketed in France and Italy","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","N/A",365.34,"37693-01-9",{"v":73,"d":"73.00"},199.81,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/clofoctol.html","C21H26Cl2O","Free Base","N/A","CC(C)(C)CC(C)(C)C1=CC(=C(O)C=C1)CC2=CC=C(Cl)C=C2Cl",7.662,0,1,5]
["S4404","Pasiniazid","b8","L3800-20","in 10mM DMSO","CFDA","N/A","N/A","Bacterial","Microbiology","Pasiniazid(Paraniazide,Pasiniazide) is a composition of isoniazid and 4-aminosalicylic acid, used to treat tuberculosis patients.",290.27,"2066-89-9",{"v":58,"d":"58.00"},199.81,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/pasiniazid.html","C6H7N3O.C7H7NO3","Isonicotinic","Paraniazide,Pasiniazide","NNC(=O)C1=CC=NC=C1.NC2=CC(=C(C=C2)C(O)=O)O",{"v":-0.34,"d":"-0.340"},3,4,2]
["S4416","Trimipramine Maleate","f8","L3800-20","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","N/A","Others","Others","N/A",410.51,"521-78-8",{"v":82,"d":"82.00"},199.75,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/trimipramine-maleate.html","C24H30N2O4","maleate","N/A","CC(CN(C)C)CN1C2=C(CCC3=CC=CC=C13)C=CC=C2.OC(=O)\\C=C/C(O)=O",{"v":1.84,"d":"1.840"},2,0,6]
["S4503","Calcium D-Panthotenate","a9","L3800-20","in 10mM DMSO","NDC","N/A","N/A","Vitamin","Metabolism","Calcium D-Panthotenate (D-Pantothenic Acid Calcium), also called vitamin B5 Calcium, is a water-soluble vitamin and an essential nutrient for many animals.",476.53,"137-08-6",{"v":44,"d":"44.00"},92.33,{"v":44,"d":"44.00"},92.33,"http://selleckchem.com/products/calcium-d-panthotenate.html","C18H32CaN2O10","free base","D-Pantothenic Acid Calcium","CC(C)(CO)C(O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)C(O)C(C)(C)CO",-1.935,6,6,16]
["S4504","6-Mercaptopurine (6-MP) Monohydrate","b9","L3800-20","in 10mM DMSO","DMF","BP2019","N/A","DNA/RNA Synthesis","DNA Damage/DNA Repair","6-Mercaptopurine (6-MP) Monohydrate is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.",170.19,"6112-76-1",{"v":34,"d":"34.00"},199.78,"<1","N/A","http://selleckchem.com/products/6-mercaptopurine-6-mp-monohydrate.html","C5H6N4OS","free base","N/A","O.S=C1N=CNC2=C1[NH]C=N2",{"v":0.16,"d":"0.160"},2,2,0]
["S4507","17-Hydroxyprogesterone","e9","L3800-20","in 10mM DMSO","N/A","N/A","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","17-Hydroxyprogesterone (17-OHP) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.",330.46,"68-96-2",{"v":66,"d":"66.00"},199.72,"<1","N/A","http://selleckchem.com/products/17-hydroxyprogesterone.html","C21H30O3","free base","N/A","CC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C",3.124,2,0,1]
["S4512","Aceglutamide","h9","L3800-20","in 10mM DMSO","DMF,CFDA","JP17;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Aceglutamide (α-N-Acetyl-L-glutamine, N2-Acetylglutamine) is a psychostimulant, nootropic agent which functions as a prodrug to glutamine with improved potency and stability.",188.18,"2490-97-3",{"v":37,"d":"37.00"},196.62,{"v":37,"d":"37.00"},196.62,"http://selleckchem.com/products/aceglutamide.html","C7H12N2O4","free base","α-N-Acetyl-L-glutamine, N2-Acetylglutamine","CC(=O)NC(CCC(N)=O)C(O)=O",-1.587,3,2,5]
["S4517","Cefotaxime sodium","d10","L3800-20","in 10mM DMSO","FDA,DMF,CFDA,PMDA,HMA","USP42-NF37;BP2019;EP9.2;JP17;IP2010;Martindale:The Extra Pharmacopoeia","Phase 4","Antibiotics,Antibiotics for Plant Cell Culture,Bacterial","Microbiology","Cefotaxime sodium(HR-756) salt is a third-generation cephalosporin antibiotic; broad-spectrum antibiotic with activity against numerous Gram-positive and Gram-negative bacteria.",477.45,"64485-93-4",{"v":95,"d":"95.00"},198.97,{"v":95,"d":"95.00"},198.97,"http://selleckchem.com/products/cefotaxime-sodium.html","C16H17N5O7S2.Na","Sodium Salt","HR-756","[Na+].CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)COC(C)=O)C3=CSC(=N3)N",-2.384,7,2,8]
["S4521","DEET","g10","L3800-20","in 10mM DMSO","NDC","Martindale the Extra Pharmacopoei, USP43-NF38, Ph.Int_6th, IP2010","N/A","Anti-infection","Microbiology","DEET (N,N-Diethyl-meta-toluamide, diethyltoluamide) is a commen active ingredient insect repellent.",191.27,"134-62-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/deet.html","C12H17NO","free base","N,N-Diethyl-meta-toluamide, diethyltoluamide","CCN(CC)C(=O)C1=CC(=CC=C1)C",2.427,1,0,3]
["S4526","Fenbufen","c11","L3800-20","in 10mM DMSO","DMF,CFDA","BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","N/A","COX","Neuronal Signaling","Fenbufen (Lederfen, CL-82204) is an orally active phenylalkanoic derivative with anti-inflammatory, analgesic and antipyretic activity. It is a non-steroidal anti-inflammatory drug.",254.28,"36330-85-5",{"v":50,"d":"50.00"},196.63,"<1","N/A","http://selleckchem.com/products/fenbufen.html","C16H14O3","free base","Lederfen, CL-82204","OC(=O)CCC(=O)C1=CC=C(C=C1)C2=CC=CC=C2",2.933,2,0,5]
["S4530","i-Inositol","f11","L3800-20","in 10mM DMSO","DMF, CFDA","EP10.4","N/A","Others","Others","i-Inositol, also known as myo-inositol, is a chemical compound which is sugar alcohol. i-Inositol is involved in a number of biological processes including insulin signal transduction, cytoskeleton transduction and so on.",180.16,"87-89-8",{"v":36,"d":"36.00"},199.82,{"v":36,"d":"36.00"},199.82,"http://selleckchem.com/products/i-inositol.html","C6H12O6","free base","myo-inositol","OC1C(O)C(O)C(O)C(O)C1O",-3.065,0,6,0]
["S4535","Methylene Blue","a2","L3800-21","in 10mM DMSO","FDA,NDC,DMF","N/A","Marketed","Dyes,Guanylate Cyclase,Microtubule Associated","GPCR & G Protein","Methylene Blue (Basic Blue 9, Tetramethylthionine chloride, methylthioninium chloride, CI-52015) is used as a dye in chromoendoscopy. It Inhibits tau filament formation with IC50 of 1.9μM. Also it inhibits soluble guanylyl cyclase.",319.85,"61-73-4",{"v":63,"d":"63.00"},196.97,{"v":63,"d":"63.00"},196.97,"http://selleckchem.com/products/methylene-blue.html","C16H18ClN3S","free base","Basic Blue 9, Tetramethylthionine chloride, methylthioninium chloride, CI-52015","[Cl-].CN(C)C1=CC2=C(C=C1)N=C3C=CC(C=C3S2)=[N+](C)C",0.369,1,0,1]
["S4536","Nitrofurantoin","b2","L3800-21","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37;BP2019;EP9.2;Ph.Int_6th;IP2010;Martindale:The Extra Pharmacopoeia","Phase 4","Antibiotics,Bacterial","Microbiology","Nitrofurantoin (Macrodantin, Furadantine, Furadonine) is an antibiotic used to treat bladder infections.It inhibits bacterial DNA, RNA, and cell wall protein synthesis.",238.16,"67-20-9",{"v":47,"d":"47.00"},197.35,"<1","N/A","http://selleckchem.com/products/nitrofurantoin.html","C8H6N4O5","free base","Macrodantin, Furadantine, Furadonine","[O-][N+](=O)C1=CC=C(O1)/C=N/N2CC(=O)NC2=O",0.105,4,1,3]
["S4541","Triclosan","e2","L3800-21","in 10mM DMSO","FDA,NDC,DMF","USP42-NF37;KP Ⅹ;Martindale:The Extra Pharmacopoeia","N/A","Bacterial","Microbiology","Triclosan (Irgasan, Cloxifenolum) is a diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.",289.54,"3380-34-5",{"v":57,"d":"57.00"},196.86,"<1","N/A","http://selleckchem.com/products/triclosan.html","C12H7Cl3O2","free base","Irgasan, Cloxifenolum","OC1=CC(=CC=C1OC2=CC=C(Cl)C=C2Cl)Cl",5.141,1,1,2]
["S4546","Xylitol","a3","L3800-21","in 10mM DMSO","DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;JP17;Martindale:The Extra Pharmacopoeia","N/A","Autophagy","Autophagy","Xylitol (Adonitol, Ribitol, Xylite, D-Xylitol, Adonite) is a sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener.",152.15,"87-99-0",{"v":30,"d":"30.00"},197.17,{"v":30,"d":"30.00"},197.17,"http://selleckchem.com/products/xylitol.html","C5H12O5","free base","Adonitol, Ribitol, Xylite, D-Xylitol, Adonite","OCC(O)C(O)C(O)CO",{"v":-2.43,"d":"-2.430"},0,5,4]
["S4548","Aminoguanidine hydrochloride","c3","L3800-21","in 10mM DMSO","DMF","USP42-NF37","N/A","NOS","Immunology & Inflammation","Aminoguanidine (Pimagedine, Guanyl hydrazine, Hydrazinecarboximidamide, Imino semicarbazide, Monoaminoguanidine) is a diamine oxidase and nitric oxide synthase inhibitor. It acts to reduce levels of advanced glycation end products (AGEs) through interacting with 3-deoxyglucosone.",110.55,"1937-19-5",{"v":22,"d":"22.00"},{"v":199,"d":"199.00"},{"v":22,"d":"22.00"},{"v":199,"d":"199.00"},"http://selleckchem.com/products/aminoguanidine-hydrochloride.html","CH6N4.HCl","hydrochloride","Pimagedine, Guanyl hydrazine, Hydrazinecarboximidamide, Imino semicarbazide, Monoaminoguanidine","Cl.NNC(N)=N",-1.098,0,3,1]
["S4553","Bronopol","f3","L3800-21","in 10mM DMSO","DMF","BP2019;Martindale:The Extra Pharmacopoeia","N/A","Bacterial","Microbiology","Bronopol (2-bromo-2-nitropropane-1,3-diol) is antibacterial agent, used as preservative in cosmetic industry.",199.99,"52-51-7",{"v":39,"d":"39.00"},195.01,{"v":39,"d":"39.00"},195.01,"http://selleckchem.com/products/bronopol.html","C3H6BrNO4","free base","N/A","OCC(Br)(CO)[N+]([O-])=O",0.056,0,2,3]
["S4561","Danthron","b4","L3800-21","in 10mM DMSO","marketed in South Africa","N/A","N/A","AMPK","PI3K/Akt/mTOR","Danthron (Chrysazin, Antrapurol) functions in regulating glucose and lipid metabolism by activating AMPK. Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron used to be a laxativa and now is currently used as an antioxidant in synthetic lubricants, in the synthesis of experimental antitumor agents, as a fungicide and as an intermediate for making dyes.",240.21,"117-10-2",{"v":4,"d":"4.00"},16.65,"<1","N/A","http://selleckchem.com/products/danthron.html","C14H8O4","free base","chrysazin, Antrapurol","OC1=CC=CC2=C1C(=O)C3=C(O)C=CC=C3C2=O",2.324,2,2,0]
["S4564","Diethylcarbamazine citrate","e4","L3800-21","in 10mM DMSO","FDA,DMF,PMDA","N/A","Phase 4","Parasite","Microbiology","Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria and is highly specific for several parasites and does not contain any toxic metallic elements.",391.42,"1642-54-2",{"v":78,"d":"78.00"},199.27,{"v":78,"d":"78.00"},199.27,"http://selleckchem.com/products/diethylcarbamazine-citrate.html","C10H21N3O.C6H8O7","citrate","N/A","CCN(CC)C(=O)N1CCN(C)CC1.OC(=O)CC(O)(CC(O)=O)C(O)=O",-3.918,4,0,7]
["S4568","Ethylvanillin","h4","L3800-21","in 10mM DMSO","N/A","USP43-NF38","N/A","Others","Others","Ethylvanillin (Ethylprotal, Bourbonal, Rhodiarome) is the organic flavorant. It is about three times as potent as vanillin and used in the production of chocolate.",166.17,"121-32-4",{"v":33,"d":"33.00"},198.59,{"v":2,"d":"2.00"},12.04,"http://www.selleckchem.com/products/ethylvanillin.html","C9H10O3","Free Base","Ethylprotal, Bourbonal, Rhodiarome","CCOC1=C(O)C=CC(=C1)C=O",1.679,2,1,3]
["S4569","Fluphenazine dihydrochloride","a5","L3800-21","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","USP42-NF37;BP2019;EP9.2;KP Ⅹ;Ph.Int_6th;IP2010;JP16;Martindale:The Extra Pharmacopoeia","N/A","Dopamine Receptor","GPCR & G Protein","Fluphenazine dihydrochloride (Prolixin) is a phenothiazine-class D1DR and D2DR inhibitor. It also inhibits  Histamine H1 Receptor.",510.44,"146-56-5",{"v":100,"d":"100.00"},195.91,{"v":100,"d":"100.00"},195.91,"http://selleckchem.com/products/fluphenazine-dihydrochloride.html","C22H26F3N3OS.2HCl","dihydrochloride","Prolixin","Cl.Cl.OCCN1CCN(CCCN2C3=C(SC4=CC=C(C=C24)C(F)(F)F)C=CC=C3)CC1",5.199,0,1,7]
["S4576","Sulfabenzamide","d5","L3800-21","in 10mM DMSO","FDA,DMF","USP42-NF37;Martindale:The Extra Pharmacopoeia","N/A","Bacterial","Microbiology","Sulfabenzamide (Sultrin, N-Sulfanilylbenzamide) is an antibacterial/antimicrobial which also exhibit their antitumor effects through multiple mechanisms including inhibition of membrane bound carbonic anhydrases, prevention of microtubule assembly, cell cycle arrest, and inhibition of angiogenesis.",276.31,"127-71-9",{"v":55,"d":"55.00"},199.05,"<1","N/A","http://selleckchem.com/products/sulfabenzamide.html","C13H12N2O3S","free base","Sultrin, N-Sulfanilylbenzamide","NC1=CC=C(C=C1)[S](=O)(=O)NC(=O)C2=CC=CC=C2",1.442,3,2,3]
["S4581","Triacetin","g5","L3800-21","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","N/A","Fungal","Microbiology","Triacetin (Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane) is a triglyceride that is used as an antifungal agent.",{"v":218.2,"d":"218.20"},"102-76-1","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/triacetin.html","C9H14O6","free base","Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane","CC(=O)OCC(COC(C)=O)OC(C)=O",-0.271,6,0,8]
["S4587","Pentylenetetrazol","c6","L3800-21","in 10mM DMSO","marketed in Italy","N/A","N/A","GABA Receptor","Neuronal Signaling","Pentylenetetrazol (Pentylenetetrazole, Metrazole, pentetrazol, pentamethylenetetrazol, Corazol, Cardiazol, PTZ) displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GABA(A) receptor antagonist.",138.17,"54-95-5",{"v":27,"d":"27.00"},195.41,{"v":27,"d":"27.00"},195.41,"http://selleckchem.com/products/pentylenetetrazol.html","C6H10N4","Free Base","Pentylenetetrazole, Metrazole, pentetrazol, pentamethylenetetrazol, Corazol, Cardiazol, PTZ","C1CC[N]2N=NN=C2CC1",0.568,3,0,0]
["S4590","Dithranol","f6","L3800-21","in 10mM DMSO","CFDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.2,Ph.Int_6th,BP2017,IP2010","Phase 4","Others","Others","Dithranol (Anthralin, cignoline, 1,8,9-trihydroxyanthracene) is one of the most important local therapeutic agents against the common skin disease, psoriasis.",226.23,"1143-38-0",{"v":7,"d":"7.00"},30.94,"N/A","N/A","http://selleckchem.com/products/dithranol.html","C14H10O3","free base","Anthralin, cignoline, 1,8,9-trihydroxyanthracene","OC1=CC=CC2=C1C(=O)C3=C(C2)C=CC=C3O",2.894,1,2,0]
["S4595","Cefazolin Sodium","b7","L3800-21","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,EP9.7,KP Ⅹ,JP17,BP2017","Marketed","Antibiotics,Bacterial","Microbiology","Cefazolin Sodium (cefazoline, cephazolin, Ancef) is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.",476.49,"27164-46-1",{"v":95,"d":"95.00"},199.37,{"v":95,"d":"95.00"},199.37,"http://selleckchem.com/products/cefazolin-sodium.html","C14H14N8O4S3.Na","sodium","cefazoline sodium, cephazolin sodium, Ancef","[Na+].CC1=NN=C(SCC2=C(N3C(SC2)C(NC(=O)C[N]4C=NN=N4)C3=O)C([O-])=O)S1",-2.807,7,1,7]
["S4599","Benzyl benzoate","e7","L3800-21","in 10mM DMSO","FDA,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017","N/A","Parasite","Microbiology","Benzyl benzoate (Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester) is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.",212.24,"120-51-4","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/benzyl-benzoate.html","C14H12O2","free base","Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester","O=C(OCC1=CC=CC=C1)C2=CC=CC=C2",3.268,2,0,4]
["S4602","Acetohydroxamic acid","h7","L3800-21","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","N/A","Bacterial","Microbiology","Acetohydroxamic acid (N-Hydroxyacetamide, Methylhydroxamic acid, Acetic acid|oxime, Lithostat,AHA) is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.",75.07,"546-88-3",{"v":15,"d":"15.00"},199.81,{"v":15,"d":"15.00"},199.81,"http://selleckchem.com/products/acetohydroxamic-acid.html","C2H5NO2","free base","N-Hydroxyacetamide, Methylhydroxamic acid, Acetic acid|oxime, Lithostat,AHA","CC(=O)NO",{"v":-0.82,"d":"-0.820"},1,1,0]
["S4603","Gallic acid","a8","L3800-21","in 10mM DMSO","NDC","EP9.1,BP2019","N/A","ROS","Immunology & Inflammation","Gallic acid (3,4,5-Trihydroxybenzoic acid, Gallate, Benzoic acid), known as powerful antioxidants, is an organic acid found in a variety of foods and herbs.",170.12,"149-91-7",{"v":34,"d":"34.00"},199.86,{"v":7,"d":"7.00"},41.15,"http://selleckchem.com/products/gallic-acid.html","C7H6O5","free base","3,4,5-Trihydroxybenzoic acid, Gallate, Benzoic acid","OC(=O)C1=CC(=C(O)C(=C1)O)O",0.733,1,3,1]
["S4609","Diflunisal","d8","L3800-21","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP7.5,BP2015","N/A","COX","Neuronal Signaling","Diflunisal (Dolobid, Dolobis, Flovacil, Fluniget,MK-647) is a difluorophenyl derivate of salicylic acid and a nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic and anti-inflammatory properties. The mechanism of action of diflunisal is as a Cyclooxygenase Inhibitor.",{"v":250.2,"d":"250.20"},"22494-42-4",{"v":50,"d":"50.00"},199.84,"<1","N/A","http://selleckchem.com/products/diflunisal.html","C13H8F2O3","free base","Dolobid, Dolobis, Flovacil, Fluniget,MK-647","OC(=O)C1=C(O)C=CC(=C1)C2=C(F)C=C(F)C=C2",3.147,1,1,2]
["S4619","Itopride hydrochloride","h8","L3800-21","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia","Marketed","AChR","Neuronal Signaling","Itopride hydrochloride (Ganaton, HSR803) is an AChE inhibitor. The IC50 of itopride with AChE is 2.04 +/- 0.27 μM.",394.89,"122892-31-3",{"v":78,"d":"78.00"},197.52,{"v":78,"d":"78.00"},197.52,"http://selleckchem.com/products/itopride-hydrochloride.html","C20H26N2O4.HCl","hydrochloride","Ganaton, HSR803","Cl.COC1=CC=C(C=C1OC)C(=O)NCC2=CC=C(OCCN(C)C)C=C2",3.093,4,1,9]
["S4623","Methylbenactyzine Bromide","c9","L3800-21","in 10mM DMSO","CFDA","N/A","N/A","AChR","Neuronal Signaling","Methylbenactyzine Bromide (Gastrimade, Noinarin, Paragone, Semulgin) is a kind of muscarinic cholinergic receptor antagonist with antispasmodic activity.",422.36,"3166-62-9",{"v":84,"d":"84.00"},198.88,{"v":84,"d":"84.00"},198.88,"http://selleckchem.com/products/methylbenactyzine-bromide.html","C21H28NO3.Br","bromide","Gastrimade, Noinarin, Paragone, Semulgin","[Br-].CC[N+](C)(CC)CCOC(=O)C(O)(C1=CC=CC=C1)C2=CC=CC=C2",-0.322,2,0,9]
["S4626","Ethosuximide","f9","L3800-21","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","Marketed","Calcium Channel","Transmembrane Transporters","Ethosuximide(Zarontin) is a succinimide anticonvulsant, used mainly in absence seizures; A calcium channel blocker.",141.17,"77-67-8",{"v":28,"d":"28.00"},198.34,{"v":28,"d":"28.00"},198.34,"http://selleckchem.com/products/ethosuximide.html","C7H11NO2","free base","Zarontin","CCC1(C)CC(=O)NC1=O",0.543,2,1,1]
["S4631","Prochlorperazine dimaleate salt","b10","L3800-21","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017,IP2010","N/A","Dopamine Receptor","Neuronal Signaling","Prochlorperazine dimaleate (Prochlorperazin, Compazine, Capazine, Stemetil) is a dopamine (D2) receptor antagonist.",606.09,"84-02-6",{"v":74,"d":"74.00"},122.09,"<1","N/A","http://selleckchem.com/products/prochlorperazine.html","C20H24ClN3S.C8H8O8","dimaleate","Prochlorperazin, Compazine, Capazine, Stemetil","CN1CCN(CCCN2C3=C(SC4=C2C=C(Cl)C=C4)C=CC=C3)CC1.OC(=O)\\C=C/C(O)=O.OC(=O)\\C=C/C(O)=O",-1.295,4,0,8]
["S4634","Sodium sulfadiazine","d10","L3800-21","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP39-NF34","Marketed","Bacterial","Microbiology","Sodium Sulfadiazine (Sulfadiazin-natrium) is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative.",272.26,"547-32-0",{"v":9,"d":"9.00"},33.06,{"v":54,"d":"54.00"},198.34,"http://selleckchem.com/products/sodium-sulfadiazine.html","C10H10N4O2S.Na","Sodium salt","Sulfadiazin-natrium","NC1=CC=C(C=C1)[S](=O)(=O)N([Na])C2=NC=CC=N2",0.417,4,1,3]
["S4637","Prasugrel Hydrochloride","g10","L3800-21","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","Marketed","P2 Receptor","Neuronal Signaling","Prasugrel hydrochloride (Prasugrel HCl, LY640315,PCR 4099 Hydrochloride)  is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.",{"v":409.9,"d":"409.90"},"389574-19-0",{"v":46,"d":"46.00"},112.22,"<1","N/A","http://selleckchem.com/products/prasugrel-hydrochloride.html","C20H20FNO3S.HCl","hydrochloride","Prasugrel HCl, LY640315,PCR 4099 Hydrochloride","Cl.CC(=O)OC1=CC2=C(CCN(C2)C(C(=O)C3CC3)C4=C(F)C=CC=C4)S1",4.183,3,0,6]
["S4638","Desogestrel","h10","L3800-21","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Desogestrel (Cerazette, Desogen, Desogestrelum, Org-2969) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.",310.47,"54024-22-5",{"v":62,"d":"62.00"},{"v":199.7,"d":"199.70"},"<1","N/A","http://selleckchem.com/products/desogestrel.html","C22H30O","free base","Cerazette, Desogen, Desogestrelum, Org-2969","CCC12CC(=C)C3C(CCC4=CCCCC34)C1CCC2(O)C#C",5.828,0,0,1]
["S4646","Ciclesonide","c11","L3800-21","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017,IP2010","Marketed","COVID-19,Glucocorticoid Receptor","Endocrinology & Hormones","Ciclesonide (Alvesco, Omnaris, RPR251526, Zetonna) is a glucocorticoid used to treat obstructive airway diseases.",540.69,"126544-47-6",{"v":100,"d":"100.00"},184.95,"<1","N/A","http://selleckchem.com/products/ciclesonide.html","C32H44O7","free base","Alvesco, Omnaris, RPR251526, Zetonna","CC(C)C(=O)OCC(=O)C12OC(OC1CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC23C)C6CCCCC6",4.696,6,1,6]
["S4650","Atipamezole","g11","L3800-21","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Adrenergic Receptor","GPCR & G Protein","Atipamezole (MPV-1248, MPV1248, Antisedan) is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug.",212.29,"104054-27-5",{"v":42,"d":"42.00"},197.84,"<1","N/A","http://selleckchem.com/products/atipamezole.html","C14H16N2","Free Base","MPV-1248, MPV1248, MPV 1248, Antisedan","CCC1(CC2=C(C1)C=CC=C2)C3=CN=C[NH]3",3.012,1,1,2]
["S4655","Sulpiride","b2","L3800-22","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.2,JP17","Marketed","Dopamine Receptor","Neuronal Signaling","Sulpiride (Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil) is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.",341.43,"15676-16-1",{"v":68,"d":"68.00"},199.16,"<1","N/A","http://selleckchem.com/products/sulpiride.html","C15H23N3O4S","free base","Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil","CCN1CCCC1CNC(=O)C2=C(OC)C=CC(=C2)[S](N)(=O)=O",0.704,4,2,6]
["S4658","Hydroquinidine","e2","L3800-22","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Hydroquinidine (Dihydroquinidine, Hydroconchinine, Hydroconquinine, Dihydroquinine) is an antiarrhythmic agent.",326.43,"1435-55-8",{"v":65,"d":"65.00"},199.12,"<1","N/A","http://selleckchem.com/products/hydroquinidine.html","C20H26N2O2","free base","Dihydroquinidine, Hydroconchinine, Hydroconquinine, Dihydroquinine","CCC1CN2CCC1CC2C(O)C3=C4C=C(OC)C=CC4=NC=C3",3.124,2,1,4]
["S4663","Fusidate Sodium","a3","L3800-22","in 10mM DMSO","DMF,CFDA,NDC,PMDA,HMA","KP Ⅹ,EP9.0","Phase 3","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Bacterial","Microbiology","Fusidate Sodium (Fucidin, SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections.",538.69,"751-94-0",{"v":100,"d":"100.00"},185.64,{"v":100,"d":"100.00"},185.64,"http://selleckchem.com/products/fusidate-sodium.html","C31H47O6.Na","sodium salt","Fucidin, Sodium fusidate, SQ-16360","[Na+].CC1C(O)CCC2(C)C1CCC3(C)C2C(O)CC4\\C(C(CC34C)OC(C)=O)=C(/CCC=C(C)C)C([O-])=O",3.623,2,2,6]
["S4666","Sivelestat sodium tetrahydrate","d3","L3800-22","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia","Marketed","Serine Protease","Proteases","Sivelestat sodium tetrahydrate (ONO5046-Na, EI546, LY544349) is a competitive inhibitor of human neutrophil elastase, also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse.",528.51,"201677-61-4",{"v":100,"d":"100.00"},189.21,"<1","N/A","http://selleckchem.com/products/sivelestat-sodium.html","C20H21N2O7S.4H2O.Na","sodium salt","Sivelestat sodium, ONO5046-Na, Sodium sivelestat, EI546 sodium, LY544349 sodium","O.O.O.O.[Na+].CC(C)(C)C(=O)OC1=CC=C(C=C1)[S](=O)(=O)NC2=CC=CC=C2C(=O)NCC([O-])=O",0.018,5,2,9]
["S4672","Dimenhydrinate","g3","L3800-22","in 10mM DMSO","FDA,CFDA,DMF,NDC,PMDA,HMA","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,KP Ⅹ,JP17,BP2017","N/A","Histamine Receptor","Neuronal Signaling","Dimenhydrinate is an over-the-counter drug used to prevent nausea, vomiting, and dizziness caused by motion sickness.",469.96,"523-87-5",{"v":94,"d":"94.00"},200.02,"<1","N/A","http://www.selleck.cn/products/dimenhydrinate.html","C24H28ClN5O3","Free Base","N/A","CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.CN3C(=O)N(C)C4=C([NH]C(=N4)Cl)C3=O",3.955,4,1,6]
["S4673","Etonogestrel","h3","L3800-22","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Etonogestrel (Implanon, Nexplanon, 3-Oxodesogestrel, 3-keto-Desogestrel) is a synthetic form of the naturally occurring female sex hormone progesterone. It binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor mediated gene expression.",324.46,"54048-10-1",{"v":64,"d":"64.00"},197.25,"<1","N/A","http://selleckchem.com/products/etonogestrel.html","C22H28O2","free base","Implanon, Nexplanon, 3-Oxodesogestrel, 3-keto-Desogestrel","CCC12CC(=C)C3C(CCC4=CC(=O)CCC34)C1CCC2(O)C#C",4.827,1,0,1]
["S4678","Povidone iodine","c4","L3800-22","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,JP17,USP39-NF34,IP2010,KP Ⅹ","Phase 2","Anti-infection,Hydrotropic Agents","Microbiology","Povidone iodine (Betadine, PVP iodine, PVP-I, Isodine) is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It is used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol.","N/A","25655-41-8",{"v":28,"d":"28.00"},{"v":10,"d":"10.00"},{"v":28,"d":"28.00"},"N/A","http://selleckchem.com/products/povidone-iodine.html","(C6H9NO)x.xI2","free base","Betadine, PVP iodine, PVP-I, Isodine","CCC(C)N1CCCC1=O",{"v":0,"d":"0.000"},0,0,0]
["S4685","Efavirenz","g4","L3800-22","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,Ph.Int_6th,IP2010","Registered","Reverse Transcriptase","Microbiology","Efavirenz (Sustiva, Stocrin, DMP-266) is a synthetic non-nucleoside reverse transcriptase (RT) inhibitor with antiviral activity.",315.67,"154598-52-4",{"v":63,"d":"63.00"},199.58,"<1","N/A","http://selleckchem.com/products/efavirenz.html","C14H9ClF3NO2","free base","Sustiva, Stocrin, DMP-266, DMP 266","FC(F)(F)C1(OC(=O)NC2=C1C=C(Cl)C=C2)C#CC3CC3",4.381,2,1,3]
["S4689","Deoxycholic acid","b5","L3800-22","in 10mM DMSO","FDA,DMF,NDC,HMA","USP42-NF37","Marketed","GPCR19","GPCR & G Protein","Deoxycholic acid (Deoxycholate, Desoxycholic acid, Cholerebic, Cholorebic) is a cytolytic agent. The physiologic effect of deoxycholic acid is by means of decreased cell membrane integrity.  Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.",392.57,"83-44-3",{"v":78,"d":"78.00"},198.69,"<1","N/A","http://selleckchem.com/products/deoxycholic-acid.html","C24H40O4","free base","Deoxycholate, Desoxycholic acid, Cholerebic, Cholorebic","CC(CCC(O)=O)C1CCC2C3CCC4CC(O)CCC4(C)C3CC(O)C12C",4.082,1,2,4]
["S4692","Succimer","e5","L3800-22","in 10mM DMSO","FDA,CFDA,DMF,NDC","Martindale the Extra Pharmacopoei","N/A","Others","Others","Succimer (DMSA, meso-2,3-dimercaptosuccinic acid) is an orally active metal chelator is used to treat heavy metal poisoning.",182.22,"304-55-2",{"v":36,"d":"36.00"},197.56,"<1","N/A","http://www.selleck.cn/products/succimer.html","C4H6O4S2","Free Base","DMSA, meso-2,3-dimercaptosuccinic acid","OC(=O)C(S)C(S)C(O)=O",0.279,2,0,3]
["S4697","Saxagliptin hydrate","a6","L3800-22","in 10mM DMSO","FDA,DMF,EMA,CFDA,NDC","N/A","Marketed","DPP","Proteases","Saxagliptin H2O (BMS-477118, Onglyza) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.",333.43,"945667-22-1",{"v":66,"d":"66.00"},197.94,{"v":1,"d":"1.00"},{"v":3,"d":"3.00"},"http://selleckchem.com/products/saxagliptin-hydrate.html","C18H25N3O2.H2O","hydrate","BMS-477118 hydrate, Onglyza hydrate, BMS 477118 hydrate, BMS477118 hydrate","O.NC(C(=O)N1C(CC2CC12)C#N)[C]34CC5[CH2]C(C[C](O)(C5)C3)C4",0.068,1,1,2]
["S4701","2-Deoxy-D-glucose (2-DG)","d6","L3800-22","in 10mM DMSO","DMF","IP2010","N/A","Apoptosis related,Carbohydrate Metabolism,HSV","Metabolism","2-Deoxy-D-glucose (2-DG, 2-deoxyglucose, NSC 15193, 2-Deoxy-D-arabino-hexose, D-Arabino-2-deoxyhexose), an analog of glucose, is a glycolytic inhibitor with antiviral activity. 2-Deoxy-D-glucose induces apoptosis and inhibits Herpes Simplex Virus type-1 (HSV-1) receptor expression.",164.16,"154-17-6",{"v":32,"d":"32.00"},194.93,{"v":32,"d":"32.00"},194.93,"http://selleckchem.com/products/2-deoxy-d-glucose.html","C6H12O5","free base","2-deoxyglucose, NSC 15193, 2-Deoxy-D-arabino-hexose, D-Arabino-2-deoxyhexose","OCC1OC(O)CC(O)C1O",-1.748,1,3,1]
["S4706","Eugenol","e6","L3800-22","in 10mM DMSO","CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017,IP2010","N/A","Immunology & Inflammation related","Immunology & Inflammation","Eugenol (4-Allyl-2-methoxyphenol, 4-Allylguaiacol, Eugenic acid, Allylguaiacol) is a naturally occuring scent chemical found in clove oil and other plants. The physiologic effect of eugenol is by means of increased Histamine Release, and cell-mediated Immunity.",{"v":164.2,"d":"164.20"},"97-53-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/eugenol.html","C10H12O2","Free Base","4-Allyl-2-methoxyphenol, 4-Allylguaiacol, Eugenic acid, Allylguaiacol","COC1=C(O)C=CC(=C1)CC=C",2.579,1,1,3]
["S4709","Latanoprost","h6","L3800-22","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","Marketed","GPR,Immunology & Inflammation related,RAR/RXR","Immunology & Inflammation","Latanoprost (Xalatan, PhXA41) is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. Latanoprost increases uveoscleral outflow and thereby reduces intraocular pressure.",432.59,"130209-82-4","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/latanoprost.html","C26H40O5","Free Base","Xalatan, PhXA41, PHXA-41","CC(C)OC(=O)CCC\\C=C/CC1C(O)CC(O)C1CCC(O)CCC2=CC=CC=C2",4.365,2,3,14]
["S4716","Evans Blue","c7","L3800-22","in 10mM DMSO","FDA","N/A","N/A","GluR","Neuronal Signaling","Evans Blue (Direct Blue 53,C.I.23860) is a potent inhibitor of the uptake of L-glutamate into synaptic vesicles, also an AMPA/kainate receptor antagonist.",960.81,"314-13-6",{"v":100,"d":"100.00"},104.08,{"v":100,"d":"100.00"},104.08,"http://selleckchem.com/products/evans-blue.html","C34H24N6O14S4.4Na","sodium salt","Direct Blue 53,C.I.23860","CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N=NC3=C(O)C4=C(N)C(=CC(=C4C=C3)[S](=O)(=O)O[Na])[S](=O)(=O)O[Na])C)N=NC5=C(O)C6=C(N)C(=CC(=C6C=C5)[S](=O)(=O)O[Na])[S](=O)(=O)O[Na]",6.593,8,4,13]
["S4720","Cefotaxime","g7","L3800-22","in 10mM DMSO","FDA,CFDA,DMF,NDC,PMDA,HMA","Martindale the Extra Pharmacopoei,USP42-NF37,EP8.8,KP Ⅹ,JP17,BP2017,IP2010","N/A","Antibiotics,Antibiotics for Plant Cell Culture,Bacterial","Microbiology","Cefotaxime(HR-756) is a third-generation cephalosporin antibiotic and has broad spectrum activity against Gram positive and Gram negative bacteria.",455.47,"63527-52-6",{"v":91,"d":"91.00"},199.79,"<1","N/A","http://www.selleck.cn/products/cefotaxime.html","C16H17N5O7S2","Free Base","HR-756","CO\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)COC(C)=O)C3=CSC(=N3)N",{"v":-0.91,"d":"-0.910"},8,2,8]
["S4723","(-)Epicatechin","a8","L3800-22","in 10mM DMSO","N/A","BP2019;Martindale:The Extra Pharmacopoeia","Phase 2","Antioxidant","Immunology & Inflammation","(−)Epicatechin (L-Epicatechin, (-)-Epicatechol) is a flavonoid present in cocoa, green tea and red wine. It is a strong antioxidant, has insulin mimic action and improves heart health.",290.27,"490-46-0",{"v":58,"d":"58.00"},199.81,"<1","N/A","http://selleckchem.com/products/-epicatechin.html","C15H14O6","free base","L-Epicatechin, (-)-Epicatechol","OC1CC2=C(OC1C3=CC(=C(O)C=C3)O)C=C(O)C=C2O",2.021,1,5,1]
["S4727","Cinnarizine","d8","L3800-22","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.2,BP2017","N/A","Calcium Channel","Transmembrane Transporters","Cinnarizine (Stugeron, Dimitronal, Stutgin, Cinarizine) is a medication derivative of piperazine, and characterized as an antihistamine and a calcium channel blocker.",368.51,"298-57-7",{"v":73,"d":"73.00"},{"v":198.1,"d":"198.10"},"<1","N/A","http://selleckchem.com/products/cinnarizine.html","C26H28N2","free base","Stugeron, Dimitronal, Stutgin, Cinarizine","C1CN(CCN1C\\C=C\\C2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=CC=C4",5.524,0,0,6]
["S4734","Retigabine 2HCl","h8","L3800-22","in 10mM DMSO","EMA","N/A","Phase 2","Potassium Channel","Transmembrane Transporters","Retigabine 2HCl (D-23129) is a novel anticonvulsant with activity in a broad range of seizure models. The mechanism of action involves opening of neuronal K(V)7.2-7.5 (formerly KCNQ2-5) voltage-activated K(+) channels.",376.25,"150812-13-8",{"v":75,"d":"75.00"},199.34,{"v":75,"d":"75.00"},199.34,"http://selleckchem.com/products/retigabine-2hcl.html","C16H18FN3O2.2HCl","dihydrochloride","N-(2-amino-4-[fluorobenzylamino]-phenyl) carbamic acid (2HCl), D-23129 2HCl","Cl.Cl.CCOC(=O)NC1=CC=C(NCC2=CC=C(F)C=C2)C=C1N",3.557,2,3,6]
["S4737","Psoralen","c9","L3800-22","in 10mM DMSO","N/A","IP2010","N/A","ADC Cytotoxin,DNA/RNA Synthesis","DNA Damage/DNA Repair","Psoralen (Psoralene, Ficusin, Furocoumarin) is a naturally occurring furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.",186.16,"66-97-7",{"v":37,"d":"37.00"},198.75,"<1","N/A","http://selleckchem.com/products/psoralen.html","C11H6O3","free base","Psoralene, Ficusin, Furocoumarin","O=C1OC2=C(C=C1)C=C3C=COC3=C2",2.203,3,0,0]
["S4744","Anethole trithione","d9","L3800-22","in 10mM DMSO","CFDA","Martindale the Extra Pharmacopoei","N/A","Others","Others","Anethole trithione is a drug used in the treatment of dry mouth.",240.36,"532-11-6",{"v":48,"d":"48.00"},{"v":199.7,"d":"199.70"},"<1","N/A","http://www.selleck.cn/products/anethole-trithione.html","C10H8OS3","Free Base","N/A","COC1=CC=C(C=C1)C2=CC(=S)SS2",3.635,1,0,2]
["S4750","Sulfacetamide sodium salt hydrate","g9","L3800-22","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017,Ph.Int_5th,USP39-NF34","Marketed","Antibiotics,Autophagy,Bacterial","Autophagy","Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase(DHPS) with IC50 of 9.5 μM. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid.",254.24,"6209-17-2",{"v":50,"d":"50.00"},196.66,{"v":50,"d":"50.00"},196.66,"http://selleckchem.com/products/sulfacetamide-sodium-salt-hydrate.html","C8H9N2O3S.H2O.Na","sodium salt hyd","N/A","O.CC(=O)N([Na])[S](=O)(=O)C1=CC=C(N)C=C1",-0.326,3,1,2]
["S4753","Ganoderic acid A","b10","L3800-22","in 10mM DMSO","N/A","EP10.4","N/A","Immunology & Inflammation related","Immunology & Inflammation","Ganoderic acid A (GAA), a representative active triterpenoid from Ganoderma lucidum, has been reported to exhibit antinociceptive, antioxidative, cytotoxic, hepatoprotective and anticancer activities.",516.67,"81907-62-2",{"v":100,"d":"100.00"},193.55,"<1","N/A","http://selleckchem.com/products/ganoderic-acid-a.html","C30H44O7","free base","N/A","CC(CC(=O)CC(C)C(O)=O)C1CC(O)C2(C)C3=C(C(=O)CC12C)C4(C)CCC(=O)C(C)(C)C4CC3O",2.775,4,2,6]
["S4768","Melibiose","f10","L3800-22","in 10mM DMSO","DMF","N/A","N/A","Others","Others","Melibiose (Galalpha1-6Glcbeta) is a nondigestible disaccharide that consists of one galactose and one glucose moiety in an alpha (1-6) glycosidic linkage.",{"v":342.3,"d":"342.30"},"585-99-9",{"v":68,"d":"68.00"},198.66,"N/A","N/A","http://selleckchem.com/products/melibiose.html","C12H22O11","free base","Galalpha1-6Glcbeta","OCC1OC(OCC(O)C(O)C(O)C(O)C=O)C(O)C(O)C1O",-4.538,3,8,8]
["S4779","Menadiol Diacetate","a11","L3800-22","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017","N/A","Vitamin","Microbiology","Menadiol Diacetate (Vitamin K4, Acetomenaphthone, Kapilin) is a synthetic hydrophilic menadione compound, which is clinically used as hemostasis medicine. It induces caspase-3-related apoptosis pathway via mitochondrial dysfunction and DNA fragmentation.",258.27,"573-20-6",{"v":51,"d":"51.00"},197.47,"N/A","N/A","http://selleckchem.com/products/menadiol-diacetate.html","C15H14O4","free base","Vitamin K4, Acetomenaphthone, Kapilin","CC(=O)OC1=C2C=CC=CC2=C(OC(C)=O)C(=C1)C",2.759,4,0,4]
["S4792","N-Acetylneuraminic acid","e11","L3800-22","in 10mM DMSO","DMF","EP8.8,BP2017,IP2010","Phase 3","Others","Others","N-Acetylneuraminic acid (Neu5Ac, NeuAc, Acido aceneuramico, Acide aceneuramique, Acidium aceneuramicum, Sialic acid, NANA) is the predominant sialic acid found in mammalian cells. Sialic acids are negatively charged monosaccharides attached to the end of sugar chains, giving rise to a wide variety of glycoproteins and glycolipids in biological fluids and cell membranes.",309.27,"131-48-6",{"v":61,"d":"61.00"},{"v":10,"d":"10.00"},"N/A","N/A","http://selleckchem.com/products/n-acetylneuraminic-acid.html","C11H19NO9","free base","Neu5Ac, NeuAc, Acido aceneuramico, Acide aceneuramique, Acidium aceneuramicum, Sialic acid","CC(=O)NC1C(O)CC(O)(OC1C(O)C(O)CO)C(O)=O",{"v":0,"d":"0.000"},0,0,0]
["S4812","Ceftizoxime","h11","L3800-22","in 10mM DMSO","FDA,DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,JP17","N/A","Antibiotics","Microbiology","Ceftizoxime is a semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. It is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.",{"v":383.4,"d":"383.40"},"68401-81-0",{"v":76,"d":"76.00"},198.23,"<1","N/A","http://selleckchem.com/products/ceftizoxime.html","C13H13N5O5S2","free base","N/A","CO\\N=C(C(=O)NC1C2SCC=C(N2C1=O)C(O)=O)\\C3=CSC(=N3)N",-0.644,6,2,5]
["S4816","Diatrizoate sodium","c2","L3800-23","in 10mM DMSO","FDA,NDC,DMF","USP39-NF34","Phase 2/3","Others","Others","Diatrizoate sodium (Amidotrizoate sodium, Hypaque sodium, Triombrin) is an iodinated radiopaque X-ray contrast medium that is used as a diagnostic aid in angiography, urography and radiography.",{"v":635.9,"d":"635.90"},"737-31-5",{"v":100,"d":"100.00"},157.26,"N/A","N/A","http://selleckchem.com/products/diatrizoate-sodium.html","C11H8I3N2O4.Na","sodium","amidotrizoate sodium, Hypaque sodium, Triombrin","[Na+].CC(=O)NC1=C(I)C(=C(I)C(=C1I)NC(C)=O)C([O-])=O",-0.039,2,2,3]
["S4817","Atenolol","d2","L3800-23","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","Marketed","Adrenergic Receptor","Neuronal Signaling","Atenolol (Tenormin, Normiten, Blokium) is a selective β1 receptor antagonist with log Kd values of −6.66±0.05, −5.99±0.14, −4.11±0.07 for binding to the human β1-, β2- and β3-adrenoceptors.",266.34,"29122-68-7",{"v":53,"d":"53.00"},198.99,{"v":35,"d":"35.00"},131.41,"http://selleckchem.com/products/atenolol.html","C14H22N2O3","free base","Tenormin, Normiten, Blokium","CC(C)NCC(O)COC1=CC=C(CC(N)=O)C=C1",0.669,2,3,8]
["S4830","Maltose","g2","L3800-23","in 10mM DMSO","DMF,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17","N/A","Others","Others","Maltose (Maltobiose, Malt Sugar, Beta-Maltose, D-Maltose), an non-essential nutrient that provides energy, is an intermediate in the intestinal digestion of glycogen and starch, and is found in germinating grains (and other plants and vegetables).",{"v":342.3,"d":"342.30"},"69-79-4",{"v":68,"d":"68.00"},198.66,"N/A","N/A","http://selleckchem.com/products/maltose.html","C12H22O11","free base","Maltobiose, Malt Sugar, Beta-Maltose, D-Maltose","OCC(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)C(O)C=O",-4.538,3,8,8]
["S4833","Cefoxitin sodium","b3","L3800-23","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,USP39-NF34","Phase 3","Antibiotics,Bacterial","Microbiology","Cefoxitin Sodium is the sodium salt form of cefoxitin, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.",449.43,"33564-30-6",{"v":89,"d":"89.00"},198.03,{"v":89,"d":"89.00"},198.03,"http://selleckchem.com/products/cefoxitin-sodium.html","C16H16N3O7S2.Na","sodium salt","N/A","[Na+].COC1(NC(=O)CC2=CC=CS2)C3SCC(=C(N3C1=O)C([O-])=O)COC(N)=O",-1.151,5,2,8]
["S4837","Ibudilast","f3","L3800-23","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17","Marketed","PDE","Metabolism","Ibudilast (KC-404, AV411, MN166) is a relatively non-selective phosphodiesterase inhibitor with anti-inflammatory and neuroprotective activities.",230.31,"50847-11-5",{"v":46,"d":"46.00"},199.73,{"v":30,"d":"30.00"},130.26,"http://selleckchem.com/products/Ibudilast.html","C14H18N2O","free base","KC-404, AV411, MN166","CC(C)C(=O)C1=C2C=CC=C[N]2N=C1C(C)C",3.339,2,0,3]
["S4841","Laurocapram","a4","L3800-23","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Laurocapram (N-Dodecylcaprolactam, Azone, N-0252, N-Lauryl caprolactam, Tranzone) is a skin penetration enhancer that facilitates absorption of cutaneously applied substances.",281.48,"59227-89-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/laurocapram.html","C18H35NO","free base","N-Dodecylcaprolactam, Azone, N-0252, N-Lauryl caprolactam, Tranzone","CCCCCCCCCCCCN1CCCCCC1=O",5.725,1,0,11]
["S4846","Meropenem Trihydrate","e4","L3800-23","in 10mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017","Marketed","Bacterial","Microbiology","Meropenem is a broad-spectrum antibacterial agent of the carbapenem family with a broad spectrum of in vitro activity against Gram-positive and Gram-negative pathogens.",437.51,"119478-56-7",{"v":87,"d":"87.00"},198.85,{"v":87,"d":"87.00"},198.85,"http://selleckchem.com/products/meropenem-trihydrate.html","C17H25N3O5S.3H2O","trihydrate","N/A","O.O.O.CC(O)C1C2C(C)C(=C(N2C1=O)C(O)=O)SC3CNC(C3)C(=O)N(C)C",{"v":-4.75,"d":"-4.750"},3,2,5]
["S4849","Levocetirizine Dihydrochloride","h4","L3800-23","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37","Marketed","Histamine Receptor","Neuronal Signaling","Levocetirizine (Xyzal, (-)-Cetirizine) is the active R-enantiomer of cetirizine and represents a new second-generation histamine H1 antagonist.",461.81,"130018-87-0",{"v":92,"d":"92.00"},199.22,{"v":92,"d":"92.00"},199.22,"http://selleckchem.com/products/levocetirizine-dihydrochloride.html","C21H25ClN2O3.2HCl","dihydrochloride","Xyzal Dihydrochloride, (-)-Cetirizine Dihydrochloride","Cl.Cl.OC(=O)COCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3",1.217,2,0,8]
["S4852","Gadopentetate Dimeglumine","c5","L3800-23","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","USP42-NF37","Marketed","Others","Others","Gadopentetate Dimeglumine (Gadopentetic acid dimeglumine, Gd-DTPA, Meglumine gadopentetate), a complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid, is an extracellular intravenous contrast agent used in magnetic resonance imaging.",{"v":938,"d":"938.00"},"86050-77-3",{"v":100,"d":"100.00"},106.61,"N/A","N/A","http://selleckchem.com/products/gadopentetate-dimeglumine.html","C14H18GdN3O10.2C7H17NO5.2H","dimeglumine salt","Gadopentetic acid dimeglumine, Gd-DTPA, Meglumine gadopentetate","CNCC(O)C(O)C(O)C(O)CO.CNCC(O)C(O)C(O)C(O)CO.OC(=O)CN1CCN2CCN(CC(O)=O)CC(=O)O[Gd](OC(=O)C2)OC(=O)C1",-13.058,8,12,16]
["S4853","Ecabet sodium","d5","L3800-23","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17","N/A","ROS","Apoptosis","Ecabet sodium (TA-2711, TA-2711E) is a widely employed mucoprotective agent for the treatment of gastric ulcers. Ecabet sodium inhibits the ability of Helicobacter pylori to induce neutrophil production of reactive oxygen species and interleukin-8, Ecabet sodium can also reduce apoptosis.",402.48,"86408-72-2",{"v":80,"d":"80.00"},198.77,{"v":16,"d":"16.00"},39.75,"http://selleckchem.com/products/ecabet-sodium.html","C20H27O5S.Na","sodium salt","TA-2711, TA-2711E","[Na+].CC(C)C1=CC2=C(C=C1[S]([O-])(=O)=O)C3(C)CCCC(C)(C3CC2)C(O)=O",2.477,1,0,3]
["S4856","Iproniazid","f5","L3800-23","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","MAO","Metabolism","Iproniazid (Marsilid, Iprazid) is a non-selective, irreversible monoamine oxidase (MAO) inhibitor (MAOI) that is used as an antidepressive agent.",179.22,"54-92-2",{"v":35,"d":"35.00"},195.29,{"v":35,"d":"35.00"},195.29,"http://selleckchem.com/products/Iproniazid.html","C9H13N3O","free base","Marsilid, Iprazid","CC(C)NNC(=O)C1=CC=NC=C1",0.121,2,2,3]
["S4862","Squalene","a6","L3800-23","in 10mM DMSO","DMF,CFDA,NDC","N/A","N/A","Fungal","Microbiology","Squalene (Spinacene, Supraene, trans-Squalene), a naturally occurring substance found in plants, animals and humans, is a component of some adjuvants that is added to vaccines to enhance the immune response.",410.72,"111-02-4","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/squalene.html","C30H50","free base","Spinacene, Supraene, trans-Squalene","CC(C)=CCC\\C(C)=C\\CC\\C(C)=C\\CC\\C=C(C)\\CC\\C=C(C)\\CCC=C(C)C",11.331,0,0,15]
["S4868","Xanthinol Nicotinate","e6","L3800-23","in 10mM DMSO","CFDA","N/A","N/A","Others","Others","Xanthinol Nicotinate (Complamin, Angioamin) is a potent vasodilator that can easily pass through the cell membrane and once inside the cell it causes an increase in glucose metabolism resulting in an increased energy.",434.45,"437-74-1",{"v":24,"d":"24.00"},55.24,"N/A","N/A","http://selleckchem.com/products/xanthinol-nicotinate.html","C13H21N5O4.C6H5NO2","Nicotinate","Complamin, Angioamin","CN(CCO)CC(O)C[N]1C=NC2=C1C(=O)N(C)C(=O)N2C.OC(=O)C3=CC=CN=C3",-3.737,5,2,7]
["S4871","Pyridoxal 5-phosphate monohydrate","h6","L3800-23","in 10mM DMSO","DMF","USP42-NF37","Phase 2","Vitamin","Metabolism","Pyridoxal 5-phosphate monohydrate is an active vitamin B6 metabolite, which is a cofactor in many reactions of amino acid metabolism.",265.16,"41468-25-1",{"v":22,"d":"22.00"},82.97,"N/A","N/A","http://selleckchem.com/products/pyridoxal-phosphate-monohydrate.html","C8H10NO6P.H2O","hydrate","N/A","O.CC1=NC=C(CO[P](O)(O)=O)C(=C1O)C=O",-0.404,3,1,4]
["S4877","Eperisone hydrochloride","d7","L3800-23","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17","N/A","Others","Others","Eperisone hydrochloride is muscle relaxant agent with antispasmodic effects. It is widely used in the treatment of patients with muscular contractures, low back pain or spasticity.",295.85,"56839-43-1",{"v":59,"d":"59.00"},199.43,"N/A","N/A","http://selleckchem.com/products/eperisone-hydrochloride.html","C17H25NO.HCl","hydrochloride","N/A","Cl.CCC1=CC=C(C=C1)C(=O)C(C)CN2CCCCC2",4.528,1,0,5]
["S4881","Calcium Dobesilate","g7","L3800-23","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,EP9.1, BP2017","Phase 2","Others","Apoptosis","Calcium dobesilate (calcium dihydroxy-2,5-benzenesulfonate) is a small molecule that has been widely used for treating diabetic retinopathy and chronic venous insufficiency.",{"v":209.2,"d":"209.20"},"20123-80-2",{"v":41,"d":"41.00"},195.98,"N/A","N/A","http://selleckchem.com/products/calcium-dobesilate.html","C6H5O5S.1/2Ca","Dobesilate","calcium dihydroxy-2,5-benzenesulfonate","OC1=CC=C(O)C(=C1)[S]([O-])(=O)=O",-0.832,0,2,1]
["S4886","Menbutone","b8","L3800-23","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Menbutone (Genabilin, Naftobil, Genabilic acid), or genabilic acid, is a derivative of oxybutyric acid which acts as a choleretic stimulating secretion, a trypsinogen and a pepsinogen.",258.27,"3562-99-0",{"v":51,"d":"51.00"},197.47,"N/A","N/A","http://selleckchem.com/products/menbutone.html","C15H14O4","Organophosphates","Genabilin, Naftobil, Genabilic acid","COC1=C2C=CC=CC2=C(C=C1)C(=O)CCC(O)=O",2.307,3,0,5]
["S4889","Perospirone hydrochloride","c8","L3800-23","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Perospirone (SM-9018) is an atypical or second-generation antipsychotic of the azapirone family that antagonizes serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist.",463.04,"129273-38-7",{"v":92,"d":"92.00"},198.69,"N/A","N/A","http://selleckchem.com/products/perospirone-hydrochloride.html","C23H30N4O2S.HCl","hydrochloride","SM-9018 hydrochloride","Cl.O=C1C2CCCCC2C(=O)N1CCCCN3CCN(CC3)C4=NSC5=C4C=CC=C5",4.423,3,0,6]
["S4894","D-Glucurone","f8","L3800-23","in 10mM DMSO","NMPA","N/A","Marketed","Others","Others","D-Glucurone is a glucuronic acid derivative that is used for treating canine hepatitis.",176.12,"32449-92-6",{"v":35,"d":"35.00"},198.73,"N/A","N/A","http://selleckchem.com/products/d-glucurone.html","C6H8O6","free base","N/A","OC1OC2C(O)C(=O)OC2C1O",-1.803,3,2,0]
["S4927","Cyclen","b9","L3800-23","in 10mM DMSO","FDA,HMA,DMF","N/A","Phase 4","Others","Others","Cyclen (1,4,7,10-tetraazacyclododecane) is a macrocycle capable of selectively binding cations that used as a ligand in chemistry for instance with chemicals used in MRI contrast agents.",172.27,"294-90-6",{"v":34,"d":"34.00"},197.36,{"v":34,"d":"34.00"},197.36,"http://selleckchem.com/products/cyclen.html","C8H20N4","free base","1,4,7,10-tetraazacyclododecane","C1CNCCNCCNCCN1",-1.589,0,4,0]
["S4935","Asunaprevir (BMS-650032)","e9","L3800-23","in 10mM DMSO","PMDA","N/A","Marketed","HCV Protease","Proteases","Asunaprevir (BMS-650032) is an orally bioavailable inhibitor of the hepatitis C virus enzyme serine protease NS3 that is necessary for protein processing required for viral replication.",748.29,"630420-16-5",{"v":100,"d":"100.00"},133.64,"<1","N/A","http://selleckchem.com/products/asunaprevir.html","C35H46ClN5O9S","free base","BMS-650032","COC1=C2C=CC(=CC2=C(OC3CC(N(C3)C(=O)C(NC(=O)OC(C)(C)C)C(C)(C)C)C(=O)NC4(CC4C=C)C(=O)N[S](=O)(=O)C5CC5)N=C1)Cl",3.565,10,3,14]
["S4941","Farnesol","h9","L3800-23","in 10mM DMSO","N/A","EP10.4","N/A","Antibiotics","Microbiology","Farnesol is a natural sesquiterpene alcohol that is potent in treating antimetabolic disorders, anti-inflammation, showing antioxidant, anticancer, and antibiotic effects.",222.37,"4602-84-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/farnesol.html","C15H26O","free base","N/A","CC(C)=CCCC(/C)=C/CCC(/C)=C/CO",{"v":4.76,"d":"4.760"},0,1,7]
["S4956","Benzamidine HCl","d10","L3800-23","in 10mM DMSO","N/A","Martindale the Extra Pharmacopoei","N/A","Serine/threonin kinase","Proteases","Benzamidine is an inhibitor of serine proteases with Ki values of 35, 350, and 220 µM for trypsin, plasmin, and thrombin, respectively.",156.61,"1670-14-0",{"v":31,"d":"31.00"},197.94,{"v":31,"d":"31.00"},197.94,"http://www.selleck.cn/products/benzamidine-hcl.html","C7H9ClN2","HCl","N/A","Cl.NC(=N)C1=CC=CC=C1",1.268,0,1,1]
["S4964","Lactobionic acid","g10","L3800-23","in 10mM DMSO","N/A","EP9.2;BP2017","N/A","MMP","Proteases","Lactobionic acid (Galactosylgluconic acid), an α-hydroxyacid (AHA) with antioxidation activity, is used in the development of cosmeceuticals for skin. Lactobionic acid inhibits matrix-metalloproteinase (MMP) activity.",{"v":358.3,"d":"358.30"},"96-82-2",{"v":71,"d":"71.00"},198.16,"N/A","N/A","http://selleckchem.com/products/lactobionic-acid.html","C12H22O12","Disaccharides","Galactosylgluconic acid","OCC(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)C(O)C(O)=O",{"v":-4.56,"d":"-4.560"},3,8,8]
["S4973","Iminostilbene","b11","L3800-23","in 10mM DMSO","DMF","N/A","N/A","Others","Others","Iminostilbene (2,3,6,7-Dibenzazepine) is a chemical precursor of carbamazepine which is used primarily in the treatment of epilepsy and neuropathic pain.",193.24,"256-96-2",{"v":38,"d":"38.00"},196.65,"N/A","N/A","http://selleckchem.com/products/iminostilbene.html","C14H11N","free base","2,3,6,7-Dibenzazepine","N1C2=C(C=CC=C2)C=CC3=CC=CC=C13",3.536,0,1,0]
["S4975","Fimasartan","c11","L3800-23","in 10mM DMSO","marketed in South Korea","N/A","Marketed","Angiotensin Receptor","GPCR & G Protein","Fimasartan (Kanarb) is a non-peptide angiotensin II receptor antagonist (ARB) with noncompetitive, insurmountable binding with the AT1 receptor. It is used for the treatment of hypertension and heart failure.",501.65,"247257-48-3",{"v":100,"d":"100.00"},199.34,"N/A","N/A","http://selleckchem.com/products/fimasartan.html","C27H31N7OS","free base","Kanarb","CCCCC1=NC(=C(CC(=S)N(C)C)C(=O)N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=N[NH]4)C",4.515,5,1,10]
["S4978","Azathramycin","f11","L3800-23","in 10mM DMSO","DMF","N/A","N/A","Antibiotics","Microbiology","Azathramycin (Azaerythromycin A, Azaerythromycin) is a macrolide antibiotic containing cladinose.",734.96,"76801-85-9",{"v":50,"d":"50.00"},68.03,"<1","N/A","http://selleckchem.com/products/azathramycin.html","C37H70N2O12","Macrolide antibiotics","Azaerythromycin A, Azaerythromycin","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)CNC(C)C(O)C1(C)O",1.542,7,4,7]
["S4991","Valpromide","b2","L3800-24","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","N/A","Epoxide Hydrolase","Metabolism","Valpromide (Depamide, Dipropylacetamide, 2-propylpentanamide) is an antiepileptic drug, derivative of Valproic acid (VPA), used as a mood-stabilizer in bipolar disorder. Valpromide inhibits both viral and cellular gene expression. Valpromide is a human epoxide hydrolase inhibitor.",143.23,"2430-27-5",{"v":28,"d":"28.00"},195.49,"N/A","N/A","http://selleckchem.com/products/valpromide.html","C8H17NO","free base","Depamide, Dipropylacetamide, 2-propylpentanamide","CCCC(CCC)C(N)=O",2.122,1,1,5]
["S4999","Avermectin B1","e2","L3800-24","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Parasite","Microbiology","Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic.",873.08,"71751-41-2",{"v":100,"d":"100.00"},114.54,"N/A","N/A","http://selleckchem.com/products/avermectin.html","C48H72O14","Macrocyclic lactones","abamectin","CCC(C)C1OC2(CC3CC(C\\C=C(C)\\C(OC4CC(OC)C(OC5CC(OC)C(O)C(C)O5)C(C)O4)C(C)\\C=C\\C=C\\6COC7C(O)C(=CC(C(=O)O3)C67O)C)O2)C=CC1C",4.692,11,2,8]
["S5002","Fingolimod (FTY720) HCl","g2","L3800-24","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8","Marketed","S1P Receptor","GPCR & G Protein","Fingolimod (FTY720, Fingolimod Hydrochloride) HCl is a S1P antagonist with IC50 of 0.033 nM in K562, and NK cells.",{"v":343.9,"d":"343.90"},"162359-56-0",{"v":69,"d":"69.00"},200.64,{"v":69,"d":"69.00"},200.64,"http://selleckchem.com/products/FTY720.html","C19H33NO2.HCl","Hydrochloride","Fingolimod Hydrochloride,FTY720","Cl.CCCCCCCCC1=CC=C(CCC(N)(CO)CO)C=C1",{"v":4.58,"d":"4.580"},0,3,12]
["S5006","Teprenone","c3","L3800-24","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17","Marketed","HSP (HSP90)","Cytoskeletal Signaling","Teprenone, an acylic polyisoprenoid, that is known as tetraprenylacetone or geranylgeranylacetone, is an anti-ulcer drug, clinically used for gastritis.  Teprenone(Geranylgeranylacetone) is an inducer of heat shock proteins (HSPs) expression.",330.55,"6809-52-5",{"v":66,"d":"66.00"},199.67,"N/A","N/A","http://selleckchem.com/products/teprenone.html","C23H38O","Isoprenoids","Geranylgeranylacetone, Tetraprenylacetone","CC(C)=CCC/C(C)=C/CC\\C(C)=C\\CC\\C(C)=C\\CCC(C)=O",7.413,1,0,12]
["S5010","Indometacin Sodium","f3","L3800-24","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia","Marketed","COX","Immunology & Inflammation","Indometacin Sodium (Indomethacin Sodium) is the sodium salt of indomethacin, which is a non-selective, reversible, and competitive inhibitor of cyclooxygenases 1 and 2 with anti-inflammatory, analgesic-antipyretic and tocolytic effects.",433.82,"74252-25-8",{"v":87,"d":"87.00"},200.55,{"v":-1,"d":"-1.00"},-2.31,"https://www.selleckchem.com/products/indometacin-sodium.html","C19H21ClNNaO7","sodium salt trihydrate","Indomethacin Sodium","O.O.O.COC1=CC2=C(C=C1)[N](C(=C2CC(=O)O[Na])C)C(=O)C3=CC=C(Cl)C=C3",3.705,4,0,5]
["S5012","Octenidine Dihydrochloride","g3","L3800-24","in 10mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia","N/A","Bacterial","Microbiology","Octenidine, a cationic surfactant, is active against gram-positive and gram-negative bacteria.",623.83,"70775-75-6",{"v":60,"d":"60.00"},96.18,"N/A","N/A","http://selleckchem.com/products/octenidine-ihydrochloride.html","C36H62N4.2HCl","Dihydrochloride","N/A","Cl.Cl.CCCCCCCCN=C1C=CN(CCCCCCCCCCN2C=CC(C=C2)=NCCCCCCCC)C=C1",{"v":10.56,"d":"10.560"},2,0,25]
["S5015","Simeprevir (TMC435)","b4","L3800-24","in 10mM DMSO","FDA,DMF,EMA,PMDA","N/A","Marketed","HCV Protease","Proteases","Simeprevir (TMC-435, TMC-435350) is a competitive, reversible, macrocyclic, noncovalent hepatitis C virus (HCV) NS3/4A protease inhibitor that acts directly against the hepatitis C virus. It has a medium inhibitory concentration (IC50) <13 nM for all HCV NS3/4A enzymes(genotypes 1a, 1b, 2, 4, 5, and 6), but has an IC50 value of 37 nM for genotype 3.",749.94,"923604-59-5",{"v":100,"d":"100.00"},133.34,"<1","N/A","http://selleckchem.com/products/simeprevir.html","C38H47N5O7S2","free base","TMC-435350","COC1=C(C)C2=NC(=CC(=C2C=C1)OC3CC4C(C3)C(=O)N(C)CCCC\\C=C/C5CC5(NC4=O)C(=O)N[S](=O)(=O)C6CC6)C7=NC(=CS7)C(C)C",4.796,9,2,8]
["S5019","Indobufen","e4","L3800-24","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","Phase 4","COX","Immunology & Inflammation","Indobufen (Ibustrin, K 3920) is a reversible platelet aggregation inhibitor. Indobufen is a reversible inhibitor of platelet cyclooxygenase (Cox) activity and suppresses thromboxane synthesis.",295.33,"63610-08-2",{"v":59,"d":"59.00"},199.78,"N/A","N/A","http://selleckchem.com/products/indobufen.html","C18H17NO3","free base","Ibustrin, K 3920","CCC(C(O)=O)C1=CC=C(C=C1)N2CC3=C(C=CC=C3)C2=O",3.157,2,0,4]
["S5027","Mebeverine Hydrochloride","a5","L3800-24","in 10mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia,EP9.8,BP2017","Phase 4","Others","Others","Mebeverine (Duspatalin, Duspatal, Colofac), a 3-phenylethylamine derivative of methoxybenzamine, acts as a musculotropic antispasmodic agent.",466.01,"2753-45-9",{"v":93,"d":"93.00"},199.57,"N/A","N/A","http://selleckchem.com/products/mebeverine-hydrochlo.html","C25H35NO5.HCl","hydrochloride","Duspatalin Hydrochloride, Duspatal Hydrochloride, Colofac Hydrochloride","Cl.CCN(CCCCOC(=O)C1=CC=C(OC)C(=C1)OC)C(C)CC2=CC=C(OC)C=C2",{"v":5.43,"d":"5.430"},5,0,14]
["S5032","Mephenesin","d5","L3800-24","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia","N/A","NMDAR","Neuronal Signaling","Mephenesin (Decontractyl, Cresoxydiol, Memphenesin, Mephedan) is centrally acting muscle relaxant, a topical analgesic and may be an NMDA receptor antagonist.",182.22,"59-47-2",{"v":36,"d":"36.00"},197.56,{"v":30,"d":"30.00"},164.64,"http://selleckchem.com/products/mephenesin.html","C10H14O3","free base","Decontractyl, Cresoxydiol, Memphenesin, Mephedan","CC1=C(OCC(O)CO)C=CC=C1",1.249,1,2,4]
["S5037","Phenazine methosulfate","g5","L3800-24","in 10mM DMSO","FDA","N/A","N/A","Others","Others","Phenazine methosulfate (N-Methylphenazonium methosulfate, 5-Methylphenazinium methyl sulfate) is widely used as an intermediate electron carrier for coupling the production of NADH or NADPH to the reduction of tetrazolium salts to coloured formazans.",306.34,"299-11-6",{"v":61,"d":"61.00"},199.13,"N/A","N/A","http://selleckchem.com/products/phenazine-methosulfate.html","C13H11N2.CH3O4S","methosulfate","N-Methylphenazonium methosulfate, 5-Methylphenazinium methyl sulfate","CO[S]([O-])(=O)=O.C[N+]1=C2C=CC=CC2=NC3=CC=CC=C13",0.727,2,0,1]
["S5042","Bevantolol hydrochloride","c6","L3800-24","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","Phase 2","Adrenergic Receptor","Neuronal Signaling","Bevantolol hydrochloride (NC-1400) is a cardioselective, beta adrenoceptor antagonist, devoid of intrinsic β sympathomimetic activity and with weak membrane-stabilizing and local anesthetic properties.",381.89,"42864-78-8",{"v":76,"d":"76.00"},199.01,{"v":52,"d":"52.00"},136.16,"http://selleckchem.com/products/bevantolol-hydrochloride.html","C20H27NO4.HCl","hydrochloride","NC-1400 hydrochloride","Cl.COC1=C(OC)C=C(CCNCC(O)COC2=CC=CC(=C2)C)C=C1",3.645,3,2,10]
["S5049","Thiocolchicoside","f6","L3800-24","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,EP9.3,BP2017,IP2010","Phase 4","GABA Receptor","Neuronal Signaling","Thiocolchicoside (Thiocolchicine 2-glucoside analog, Coltramyl) is a natural occuring glycoside originated from the flower seeds of superba gloriosa with anti-inflammatory and analgesic properties as well as pronounced convulsant activity. It is also an antagonist of GABAA receptor.",563.62,"602-41-5",{"v":100,"d":"100.00"},177.42,{"v":100,"d":"100.00"},177.42,"http://selleckchem.com/products/thiocolchicoside.html","C27H33NO10S","Phenolic glycosides","Thiocolchicine 2-glucoside analog, Coltramyl","COC1=C(OC)C2=C(CCC(NC(C)=O)C3=CC(=O)C(=CC=C23)SC)C=C1OC4OC(CO)C(O)C(O)C4O",0.446,6,5,7]
["S5052","Granisetron","g6","L3800-24","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,BP2017","Marketed","5-HT Receptor","Neuronal Signaling","Granisetron (Sancuso, Kevatril, Granisetronum, Sustol) is a serotonin receptor (5HT-3 selective) antagonist that is used as an antiemetic and antinauseant for cancer chemotherapy.",312.41,"109889-09-0",{"v":11,"d":"11.00"},35.21,"N/A","N/A","http://selleckchem.com/products/granisetron.html","C18H24N4O","Serotonin 5-HT3 receptor","Sancuso, Kevatril, Granisetronum, Sustol","CN1C2CCCC1CC(C2)NC(=O)C3=N[N](C)C4=C3C=CC=C4",2.401,2,1,2]
["S5055","Milbemycin Oxime","b7","L3800-24","in 10mM DMSO","N/A","USP42-NF37;EP9.2;BP2019","N/A","Parasite","Microbiology","Milbemycin Oxime is a broad spectrum anti-parasitic drug that is active against worms (anthelmintic) and mites (miticide).","N/A","129496-10-2",{"v":100,"d":"100.00"},{"v":10,"d":"10.00"},"<1","N/A","http://selleckchem.com/products/milbemycin-oxime.html","C30H40NO7R2","Macrocyclic lactones","N/A","CC1C(OC2(CC1)CC3CC(C/C=C(C)/CC(C)\\C=C\\C=C\\4COC5/C(=N/O)C(=CC(C(=O)O3)C45O)C)O2)[R]",4.783,6,0,0]
["S5059","Pixantrone Maleate","e7","L3800-24","in 10mM DMSO","EMA","Martindale:The Extra Pharmacopoeia","Marketed","Topoisomerase","DNA Damage/DNA Repair","Pixantrone (BBR-2778) is a novel aza-anthracenedione compound with antitumor activity. It is a weak topoisomerase II inhibitor and forms stable DNA adducts through alkylation with specificity for DNA hypermethylated sites.",557.51,"144675-97-8",{"v":100,"d":"100.00"},179.37,{"v":100,"d":"100.00"},179.37,"http://selleckchem.com/products/pixantrone-maleate.html","C17H19N5O2.2C4H4O4","dimaleate","BBR-2778","NCCNC1=CC=C(NCCN)C2=C1C(=O)C3=C(C=NC=C3)C2=O.OC(=O)\\C=C/C(O)=O.OC(=O)\\C=C/C(O)=O",-5.263,7,4,10]
["S5065","Ganciclovir sodium","a8","L3800-24","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","Marketed","CMV","Microbiology","Ganciclovir Sodium (RS-21592, Cytovene IV, BW 759, 2'-Nor-2'-deoxyguanosine) is the sodium salt form of ganciclovir, a synthetic, antiviral, purine nucleoside analog with antiviral activity, especially against cytomegalovirus (CMV).",277.21,"107910-75-8",{"v":55,"d":"55.00"},198.41,{"v":55,"d":"55.00"},198.41,"https://www.selleckchem.com/products/ganciclovir-sodium.html","C9H12N5NaO4","Nucleoside","RS-21592 sodium, Cytovene IV sodium, BW 759 sodium, 2'-Nor-2'-deoxyguanosine sodium","[Na+].NC1=NC2=C(N=C[N]2COC(CO)CO)C(=N1)[O-]",-1.859,4,3,5]
["S5069","Dabrafenib Mesylate","d8","L3800-24","in 10mM DMSO","FDA,DMF","N/A","Marketed","Raf","MAPK","Dabrafenib Mesylate (GSK2118436) is the mesylate salt form of dabrafenib, an orally bioavailable inhibitor of B-raf (BRAF) protein with IC50s of 0.8 nM, 3.2 nM and 5 nM for B-Raf (V600E), B-Raf (WT) and C-Raf, respectively.",615.67,"1195768-06-9",{"v":100,"d":"100.00"},162.42,"<1","N/A","http://selleckchem.com/products/dabrafenib-mesylate.html","C23H20F3N5O2S2.CH4O3S","mesylate","GSK2118436 Mesylate","CC(C)(C)C1=NC(=C(S1)C2=CC=NC(=N2)N)C3=C(F)C(=CC=C3)N[S](=O)(=O)C4=C(F)C=CC=C4F.C[S](O)(=O)=O",4.963,5,2,6]
["S5073","Donepezil","g8","L3800-24","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,JP17,IP2010","Marketed","AChR","Neuronal Signaling","Donepezil (Aricept, Donepezilo) is a piperidine based, potent, specific, non-competitive and reversible inhibitor of acetylcholinesterase (AChE) used for the treatment of mild to moderate dementia of the Alzheimer's type.",379.49,"120014-06-4",{"v":75,"d":"75.00"},197.63,"N/A","N/A","http://selleckchem.com/products/donepezil.html","C24H29NO3","free base","Aricept, Donepezilo","COC1=CC2=C(C=C1OC)C(=O)C(CC3CCN(CC3)CC4=CC=CC=C4)C2",4.569,3,0,6]
["S5077","Regorafenib (BAY-734506) Monohydrate","c9","L3800-24","in 10mM DMSO","FDA,DMF,EMA,NDC","EP9.8","Marketed","c-Kit,c-RET,PDGFR,Raf,VEGFR","Protein Tyrosine Kinase","Regorafenib (BAY-734506, Fluoro-sorafenib, Resihance, Stivarga, regorafaenib monohydrate) Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, Kit (c-Kit), RET (c-RET), RAF-1, B-RAF and B-RAF(V600E) respectively.",500.83,"1019206-88-2",{"v":100,"d":"100.00"},199.67,"N/A","N/A","http://selleckchem.com/products/regorafenib-monohydrate.html","C21H15ClF4N4O3.H2O","monohydrate","Fluoro-sorafenib, Resihance, Stivarga, regorafaenib monohydrate","O.CNC(=O)C1=NC=CC(=C1)OC2=CC=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C(=C2)F",4.174,4,3,6]
["S5081","Ceforanide","f9","L3800-24","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","N/A","Bacterial","Microbiology","Ceforanide is a new cephalosporin with antibacterial activity and has a longer elimination half-life than any currently available cephalosporin.",519.55,"60925-61-3",{"v":6,"d":"6.00"},11.55,"N/A","N/A","http://selleckchem.com/products/ceforanide.html","C20H21N7O6S2","free base","N/A","NCC1=CC=CC=C1CC(=O)NC2C3SCC(=C(N3C2=O)C(O)=O)CSC4=NN=N[N]4CC(O)=O",-3.235,7,2,10]
["S5082","Vitamin K2","g9","L3800-24","in 10mM DMSO","CFDA","N/A","Marketed","Vitamin","Metabolism","Vitamin K2 (Menaquinone) is an important fat-soluble vitamin that plays critical roles in protecting heart and brain, and building strong bones. It also plays an important role in cancer protection.",444.65,"863-61-6",{"v":88,"d":"88.00"},197.91,"N/A","N/A","http://selleckchem.com/products/vitamin-k2.html","C31H40O2","free base","Menaquinone","CC(C)=CCC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC1=C(C)C(=O)C2=C(C=CC=C2)C1=O",{"v":9.5,"d":"9.500"},2,0,11]
["S5085","Azamethiphos","b10","L3800-24","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Azamethiphos is an organophosphate (OP) pesticide used to combat sea lice infestations in farmed salmonids.",324.68,"35575-96-3",{"v":64,"d":"64.00"},197.12,"N/A","N/A","http://selleckchem.com/products/azamethiphos.html","C9H10ClN2O5PS","free base","N/A","CO[P](=O)(OC)SCN1C(=O)OC2=C1N=CC(=C2)Cl",1.793,5,0,5]
["S5093","Rafoxanide","f10","L3800-24","in 10mM DMSO","N/A","IP2010","N/A","Parasite","Microbiology","Rafoxanide (Disalan, Ranide, Flukanide, Bovanide) is a salicylanilide used as an anthelmintic, being effective treatment for the control of fluke infections in animals.",626.01,"22662-39-1",{"v":100,"d":"100.00"},159.74,"N/A","N/A","http://selleckchem.com/products/rafoxanide.html","C19H11Cl2I2NO3","free base","Disalan, Ranide, Flukanide, Bovanide","OC1=C(I)C=C(I)C=C1C(=O)NC2=CC(=C(OC3=CC=C(Cl)C=C3)C=C2)Cl",6.418,2,2,4]
["S5100","Pralidoxime Iodide","h10","L3800-24","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia","N/A","AChR","Neuronal Signaling","Pralidoxime Iodide (2-PAM) is an antidote approved for reactivation of inhibited acetylcholinesterase (AChE) in organophosphate poisoning.",264.06,"94-63-3",{"v":52,"d":"52.00"},196.92,"N/A","N/A","http://selleckchem.com/products/pralidoxime-lodide.html","C7H9N2O.I","iodide salt","2-PAM","[I-].C[N+]1=C(C=CC=C1)\\C=N\\O",{"v":-1.56,"d":"-1.560"},1,0,1]
["S5106","Lanolin","c11","L3800-24","in 10mM DMSO","DMF,NDC,PMDA,HMA","USP42-NF37,KP Ⅹ,JP16","Phase 4","Others","Others","Lanolin (wool wax, wool grease) is a wax secreted by the sebaceous glands of wool-bearing animals and used widely in the pharmaceutical and cosmetics industries.","N/A","8006-54-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/lanolin.html","N/A","Lipids","wool wax, wool grease","N/A",{"v":0,"d":"0.000"},0,0,0]
["S5113","Propyl gallate","g11","L3800-24","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","N/A","PPAR","Metabolism","Propyl gallate (Gallic acid propyl esterZ, n-Propyl gallate) is an antioxidant used in foods especially animal fats and vegetable oils, also in a wide variety of cosmetics and beauty care products.",{"v":212.2,"d":"212.20"},"121-79-9",{"v":42,"d":"42.00"},197.93,"N/A","N/A","http://selleckchem.com/products/propyl-gallate.html","C10H12O5","free base","Gallic acid propyl esterZ, n-Propyl gallate","CCCOC(=O)C1=CC(=C(O)C(=C1)O)O",{"v":0,"d":"0.000"},0,0,0]
["S5121","Phytol","b2","L3800-25","in 10mM DMSO","NDC","N/A","N/A","PPAR","Metabolism","Phytol (Trans-Phytol), a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, shows antinociceptive and antioxidant activities as well as anti-inflammatory and antiallergic effects. It is a specific activator of PPARα.",296.53,"150-86-7","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/phytol.html","C20H40O","free base","Trans-Phytol","CC(C)CCCC(C)CCCC(C)CCC\\C(C)=C\\CO",{"v":0,"d":"0.000"},0,0,0]
["S5132","Casanthranol","e2","L3800-25","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","N/A","Others","Others","Casanthranol is a purified mixture of te antranol glycosides derived from Cascara sagrada.","N/A","8024-48-4",{"v":100,"d":"100.00"},"N/A","N/A","N/A","http://selleckchem.com/products/casanthranol.html","C26H44NNaO7RS","Anthraquinone laxatives","N/A","N/A",{"v":0,"d":"0.000"},0,0,0]
["S5134","D(-)-Arabinose","f2","L3800-25","in 10mM DMSO","N/A","EP9.2;BP2018","N/A","Others","Others","D-Arabinose is a reducing sugar useful as a substrate in analysis of arabinose isomerases and synthesis of D-erythroascorbic acid in yeast.",150.13,"28697-53-2",{"v":30,"d":"30.00"},199.83,"N/A","N/A","http://selleckchem.com/products/d-arabinose.html","C5H10O5","free base","D-arabinose","OC1COC(O)C(O)C1O",{"v":0,"d":"0.000"},0,0,0]
["S5143","Citropten","a3","L3800-25","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Others","Others","Citropten (5,7-Dimethoxycoumarin, Citroptene, Limettin, Limetin) is a natural organic compound  which belongs to coumarins and derivatives class.",206.19,"487-06-9",{"v":41,"d":"41.00"},198.85,"N/A","N/A","http://selleckchem.com/products/citropten.html","C11H10O4","free base","5,7-Dimethoxycoumarin, Citroptene, Limettin, Limetin","COC1=CC2=C(C=CC(=O)O2)C(=C1)OC",{"v":0,"d":"0.000"},0,0,0]
["S5157","Thymol","d3","L3800-25","in 10mM DMSO","CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,EP9.2,JP17,BP2017,USP38-NF33,JP16","N/A","Immunology & Inflammation related","Immunology & Inflammation","Thymol (2-isopropyl-5-methylphenol, IPMP), a naturally occurring monocyclic phenolic compound derived from Thymus vulgaris (Lamiaceae), has been reported to exhibit anti-inflammatory property in vivo and vitro.",150.22,"89-83-8",{"v":30,"d":"30.00"},199.71,"N/A","N/A","http://selleckchem.com/products/thymol.html","C10H14O","free base","2-isopropyl-5-methylphenol, IPMP","CC(C)C1=CC=C(C)C=C1O",{"v":0,"d":"0.000"},0,0,0]
["S5167","Benzyl cinnamate","h3","L3800-25","in 10mM DMSO","N/A","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Benzyl cinnamate (Cinnamein, Benzylcinnamoate, Benzyl 3-phenylpropenoate, Cinnamic acid benzyl ester), a flavouring agent isolated from various plant species, is used in heavy oriental perfumes and as a fixative.",238.28,"103-41-3",{"v":47,"d":"47.00"},197.25,"N/A","N/A","http://selleckchem.com/products/benzyl-cinnamate.html","C16H14O2","free base","Cinnamein, Benzylcinnamoate, Benzyl 3-phenylpropenoate, Cinnamic acid benzyl ester","O=C(OCC1=CC=CC=C1)/C=C/C2=CC=CC=C2",{"v":0,"d":"0.000"},0,0,0]
["S5177","Naproxen","c4","L3800-25","in 10mM DMSO","DMF,NDC,FDA,CFDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,BP2017,IP2010,JP16,CP2005","Marketed","COX","Immunology & Inflammation","Naproxen is an anti-inflammatory agent with analgesic and antipyretic properties. It is a nonselective inhibitor of COX-1 and COX-2.",230.26,"22204-53-1",{"v":46,"d":"46.00"},199.77,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/naproxen.html","C14H14O3","Free Base","N/A","COC1=CC2=CC=C(C=C2C=C1)C(C)C(O)=O",2.849,2,0,3]
["S5205","Nilotinib hydrochloride","g4","L3800-25","in 10mM DMSO","FDA,DMF,PMDA","Martindale:The Extra Pharmacopoeia,EP9.8","Marketed","Bcr-Abl","Angiogenesis","Nilotinib hydrochloride (AMN-107) is the hydrochloride salt form of nilotinib, an orally bioavailable Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity.",565.98,"923288-95-3",{"v":100,"d":"100.00"},176.69,{"v":-1,"d":"-1.00"},-1.77,"http://selleckchem.com/products/nilotinib-hydrochloride.html","C28H22F3N7O.HCl","hydrochloride","AMN-107 HCl","Cl.CC1=C[N](C=N1)C2=CC(=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C)C(=C3)NC4=NC=CC(=N4)C5=CC=CN=C5",5.466,5,2,7]
["S5209","Enoxacin Sesquihydrate","b5","L3800-25","in 10mM DMSO","DMF","N/A","N/A","Bacterial","Microbiology","Enoxacin sesquihydrate (Enoxacin hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.",347.34,"84294-96-2",{"v":4,"d":"4.00"},11.52,"N/A","N/A","http://selleckchem.com/products/enoxacin-sesquihydrate.html","C15H17FN4O3.3/2H2O","sesquihydrate","Enoxacin hydrate","CCN1C=C(C(O)=O)C(=O)C2=C1N=C(N3CCNCC3)C(=C2)F",-0.749,3,1,3]
["S5212","Imidazolidinyl Urea","e5","L3800-25","in 10mM DMSO","DMF","USP43-NF38","N/A","Anti-infection","Microbiology","Imidazolidinyl Urea (Imidurea) is an antimicrobial agent used as preservative in cosmetics.",388.29,"39236-46-9",{"v":77,"d":"77.00"},198.31,"N/A","N/A","http://selleckchem.com/products/imidazolidinyl-urea.html","C11H16N8O8","free base","Imidurea","OCN1C(NC(=O)NCNC(=O)NC2N(CO)C(=O)NC2=O)C(=O)NC1=O",-4.009,6,8,6]
["S5213","Piroctone Olamine","f5","L3800-25","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Fungal","Microbiology","Piroctone Olamine (piroctone ethanolamine) is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff,fungal infections.",298.42,"68890-66-4",{"v":38,"d":"38.00"},127.34,"<1","N/A","http://selleckchem.com/products/piroctone-olamine.html","C14H23NO2.C2H7NO","Ethanolamines","piroctone ethanolamine","CC(CC1=CC(=CC(=O)N1O)C)CC(C)(C)C.NCCO",2.064,1,2,5]
["S5217","Arformoterol Tartrate","a6","L3800-25","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","Marketed","Adrenergic Receptor","Neuronal Signaling","Arformoterol Tartrate is the tartrate salt of arformoterol, a long-acting beta-2 adrenergic agonist with bronchodilator activity.",494.49,"200815-49-2",{"v":99,"d":"99.00"},200.21,{"v":-1,"d":"-1.00"},-2.02,"https://www.selleckchem.com/products/arformoterol-tartrate.html","C23H30N2O10","Tartrate","(R, R)-Formoterol","COC1=CC=C(CC(C)NCC(O)C2=CC(=C(O)C=C2)NC=O)C=C1.OC(C(O)C(O)=O)C(O)=O",-2.446,4,6,11]
["S5227","Erythromycin thiocyanate","d6","L3800-25","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,CP2005,USP36-NF31,BP2013,JP15","Registered","Antibiotics,Bacterial","Microbiology","Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits and inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.",793.02,"7704-67-8",{"v":100,"d":"100.00"},{"v":126.1,"d":"126.10"},"N/A","N/A","http://selleckchem.com/products/erythromycin-thiocyanate.html","C37H67NO13.CHNS","thiocyanate","N/A","CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)C(=O)C(C)C(O)C1(C)O.SC#N",2.337,8,3,7]
["S5234","Nintedanib Ethanesulfonate Salt","h6","L3800-25","in 10mM DMSO","PMDA","N/A","Marketed","FGFR,PDGFR,VEGFR","Protein Tyrosine Kinase","Nintedanib (Intedanib, BIBF 1120) is a small molecule tyrosine-kinase inhibitor with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β, respectively.",649.76,"656247-18-6",{"v":100,"d":"100.00"},{"v":153.9,"d":"153.90"},{"v":100,"d":"100.00"},{"v":153.9,"d":"153.90"},"http://selleckchem.com/products/nintedanib-ethanesulfonate-salt.html","C31H33N5O4.C2H6O3S","ethanesulfonate","Intedanib, BIBF 1120","CC[S](O)(=O)=O.COC(=O)C1=CC2=C(C=C1)C(/C(=O)N2)=C(NC3=CC=C(C=C3)N(C)C(=O)CN4CCN(C)CC4)\\C5=CC=CC=C5",{"v":2.9,"d":"2.900"},4,2,9]
["S5240","Lenvatinib (E7080) Mesylate","c7","L3800-25","in 10mM DMSO","FDA,DMF","N/A","Marketed","c-Kit,c-RET,FGFR,PDGFR,VEGFR","Protein Tyrosine Kinase","Lenvatinib Mesylate (E7080) is a synthetic, orally available tyrosine kinase inhibitor that inhibits vascular endothelial growth factor receptor (VEGFR1-3), fibroblast growth factor receptor (FGFR1-4), platelet-derived growth factor receptor α (PDGFRα), stem cell factor receptor (Kit (c-Kit)), and rearranged during transfection (RET (c-RET)). Lenvatinib Mesylate has potential antineoplastic activity.",522.96,"857890-39-2",{"v":39,"d":"39.00"},74.58,{"v":-1,"d":"-1.00"},-1.91,"http://selleckchem.com/products/lenvatinib-mesylate.html","C21H19ClN4O4.CH4O3S","Mesylate","E7080 mesylate","COC1=C(C=C2C(=CC=NC2=C1)OC3=CC(=C(NC(=O)NC4CC4)C=C3)Cl)C(N)=O.C[S](O)(=O)=O",2.418,5,3,6]
["S5245","Raltegravir potassium","g7","L3800-25","in 10mM DMSO","FDA,DMF,EMA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4","Marketed","Integrase","Microbiology","Raltegravir Potassium(MK-0518 potassium) is the orally bioavailable potassium salt of raltegravir, the first approved human immunodeficiency virus type 1 (HIV-1) integrase inhibitor.",482.51,"871038-72-1",{"v":96,"d":"96.00"},198.96,"<1","N/A","http://selleckchem.com/products/raltegravir-potassium.html","C20H20FN6O5.K","potassium salt","MK-0518 potassium","[K+].CN1C(=O)C(=C(N=C1C(C)(C)NC(=O)C2=NN=C(C)O2)C(=O)NCC3=CC=C(F)C=C3)[O-]",-0.994,7,2,6]
["S5247","Selamectin","a8","L3800-25","in 10mM DMSO","EMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017","N/A","Parasite","Microbiology","Selamectin (UK-124114) is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a  wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas.",769.96,"220119-17-5",{"v":100,"d":"100.00"},129.88,"N/A","N/A","https://www.selleckchem.com/products/selamectin.html","C43H63NO11","free base","UK-124114","COC1CC(OC(C)C1O)OC/2C(C)\\C=C\\C=C\\3COC4/C(=N/O)C(=CC(C(=O)OC5CC(C\\C=C2C)OC6(CCC(C)C(O6)C7CCCCC7)C5)C34O)C",5.315,9,1,4]
["S5254","Dasatinib hydrochloride","d8","L3800-25","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Bcr-Abl,kit,Src","Angiogenesis","Dasatinib hydrochloride (BMS-354825) is the hydrochloride salt form of dasatinib, an inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively.",524.47,"854001-07-3",{"v":100,"d":"100.00"},190.67,{"v":11,"d":"11.00"},20.97,"https://www.selleckchem.com/products/dasatinib-hydrochloride.html","C22H27Cl2N7O2S","hydrochloride","BMS-354825 HCl","Cl.CC1=NC(=CC(=N1)NC2=NC=C(S2)C(=O)NC3=C(C)C=CC=C3Cl)N4CCN(CCO)CC4",3.821,4,3,7]
["S5255","Nicardipine","e8","L3800-25","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,EP9.3,KP Ⅹ,JP17","N/A","Calcium Channel","Transmembrane Transporters","Nicardipine is a potent calcium channel blockader with marked vasodilator action.",479.52,"55985-32-5",{"v":95,"d":"95.00"},198.11,{"v":30,"d":"30.00"},62.56,"https://www.selleckchem.com/products/nicardipine.html","C26H29N3O6","Dihydropyridine calcium channel blocker","YC-93","COC(=O)C1=C(C)NC(=C(C1C2=CC=CC(=C2)[N+]([O-])=O)C(=O)OCCN(C)CC3=CC=CC=C3)C",3.488,4,1,11]
["S5258","Revefenacin","h8","L3800-25","in 10mM DMSO","FDA,NDC","N/A","Registered","AChR","Neuronal Signaling","Revefenacin (TD-4208, GSK-1160724) is a potent, lung-selective, long-acting muscarinic antagonist that may be for the treatment of respiratory disease.",597.75,"864750-70-9",{"v":100,"d":"100.00"},167.29,"<1","N/A","http://selleckchem.com/products/revefenacin.html","C35H43N5O4","Quinuclidinyl","TD-4208, GSK-1160724","CN(CCN1CCC(CC1)OC(=O)NC2=CC=CC=C2C3=CC=CC=C3)C(=O)C4=CC=C(CN5CCC(CC5)C(N)=O)C=C4",3.833,4,2,11]
["S5269","J147","d9","L3800-25","in 10mM DMSO","N/A","N/A","Phase 1","MAO","Neuronal Signaling","J147, a curcumin derivative, is a potent neurogenic and neuroprotective compound developed for the treatment of neurodegenerative conditions associated with aging.",350.33,"1146963-51-0",{"v":70,"d":"70.00"},199.81,"N/A","N/A","http://selleckchem.com/products/j147.html","C18H17F3N2O2","free base","N/A","COC1=CC(=CC=C1)/C=N/N(C(=O)C(F)(F)F)C2=CC=C(C)C=C2C",4.845,3,0,5]
["S5279","Fendiline hydrochloride","g9","L3800-25","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Calcium Channel,Ras","Transmembrane Transporters","Fendiline hydrochloride is the hydrochloride salt form of Fendiline, which is an L-type calcium channel blocker and also a specific inhibitor of K-Ras plasma membrane targeting with no detectable effect on the localization of H- and N-Ras.",351.91,"13636-18-5",{"v":70,"d":"70.00"},198.91,"N/A","N/A","http://selleckchem.com/products/fendiline-hydrochloride.html","C23H25N.HCl","hydrochloride","N/A","Cl.CC(NCCC(C1=CC=CC=C1)C2=CC=CC=C2)C3=CC=CC=C3",5.772,0,1,7]
["S5284","Adenosine 5'-monophosphate monohydrate","b10","L3800-25","in 10mM DMSO","DMF","N/A","N/A","AMPK","PI3K/Akt/mTOR","Adenosine 5'-monophosphate monohydrate (5'-Adenylic acid, 5'-AMP) is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK).",365.24,"18422-05-4",{"v":9,"d":"9.00"},24.64,"N/A","N/A","http://selleckchem.com/products/adenosine-5-monophosphate-monohydrate.html","C10H14N5O7P.H2O","hydrate","5'-Adenylic acid, 5'-AMP","O.NC1=NC=NC2=C1N=C[N]2C3OC(CO[P](O)(O)=O)C(O)C3O",{"v":-2.16,"d":"-2.160"},5,3,4]
["S5289","Ceftezole","f10","L3800-25","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,CP2005","N/A","Bacterial","Microbiology","Ceftezole (Celoslin, Falomesin) is a semi-synthetic first-generation cephalosporin with antibacterial activity.",440.48,"26973-24-0",{"v":88,"d":"88.00"},199.78,"N/A","N/A","http://selleckchem.com/products/ceftezole.html","C13H12N8O4S3","free base","Celoslin, Falomesin","OC(=O)C1=C(CSC2C(NC(=O)C[N]3C=NN=N3)C(=O)N12)CSC4=NN=CS4",-1.594,8,1,7]
["S5293","Nimustine Hydrochloride","a11","L3800-25","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","Phase 2","DNA/RNA Synthesis","DNA Damage/DNA Repair","Nimustine Hydrochloride (Nidran) is the hydrochloride salt of nimustine, a nitrosourea with antineoplastic activity that alkylates and crosslinks DNA, thereby causing DNA fragmentation, inhibition of protein synthesis, and cell death.",309.15,"55661-38-6",{"v":61,"d":"61.00"},197.32,"N/A","N/A","http://selleckchem.com/products/nimustine-hydrochloride.html","C9H13ClN6O2.HCl","hydrochloride","Nidran hydrochloride","Cl.CC1=NC=C(CNC(=O)N(CCCl)N=O)C(=N1)N",{"v":0.47,"d":"0.470"},4,2,5]
["S5297","Vidarabine monohydrate","d11","L3800-25","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia","Phase 3","DNA/RNA Synthesis","DNA Damage/DNA Repair","Vidarabine (Spongoadenosine, Vira-A) is a nucleoside antibiotic with antiviral acitivity that interferes with the synthesis of viral DNA. It is used to treat herpes simplex and varicella zoster viruses.",285.26,"24356-66-9",{"v":57,"d":"57.00"},199.82,"N/A","N/A","http://selleckchem.com/products/vidarabine-monohydrate.html","C10H13N5O4.H2O","hydrate","Spongoadenosine monohydrate, Vira-A monohydrate","O.NC1=NC=NC2=C1N=C[N]2C3OC(CO)C(O)C3O",-2.088,4,4,2]
["S5298","Amoxicillin trihydrate","e11","L3800-25","in 10mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,Ph.Int_6th,BP2017,IP2010","Marketed","Antibiotics,Bacterial","Microbiology","Amoxicillin (Amoxil, Amoxipen, Moxaline) is a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity.",419.45,"61336-70-7",{"v":30,"d":"30.00"},71.52,"N/A","N/A","http://selleckchem.com/products/amoxicillin-trihydrate.html","C16H19N3O5S.3H2O","trihydrate","Amoxil trihydrate, Amoxipen trihydrate, Moxaline trihydrate","O.O.O.CC1(C)SC2C(NC(=O)C(N)C3=CC=C(O)C=C3)C(=O)N2C1C(O)=O",-3.161,3,3,4]
["S5302","6-Methoxy-2-naphthoic acid","h11","L3800-25","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","NMDAR","Neuronal Signaling","6-Methoxy-2-naphthoic acid (6-Methoxy-2-naphthalenecarboxylic acid) is an modulator of NMDAR.",202.21,"2471-70-7",{"v":40,"d":"40.00"},197.81,"<1","N/A","http://selleckchem.com/products/6-methoxy-2-naphthoic-acid.html","C12H10O3","free base","6-Methoxy-2-naphthalenecarboxylic acid","COC1=CC2=CC=C(C=C2C=C1)C(O)=O",2.351,2,0,2]
["S5312","Urolithin A","d2","L3800-26","in 10mM DMSO","N/A","N/A","Phase 2","Mitophagy","Autophagy","Urolithin A (3,8-Dihydroxy Urolithin, 2',7-Dihydroxy-3,4-benzocoumarin), a metabolite of ellagitannin, is a first-in-class natural compound that induces mitophagy both in vitro and in vivo following oral consumption.",{"v":228.2,"d":"228.20"},"1143-70-0",{"v":45,"d":"45.00"},{"v":197.2,"d":"197.20"},"<1","N/A","http://selleckchem.com/products/urolithin-a.html","C13H8O4","free base","3,8-Dihydroxy Urolithin; 2',7-Dihydroxy-3,4-benzocoumarin","OC1=CC=C2C(=C1)OC(=O)C3=CC(=CC=C23)O",2.466,2,2,0]
["S5320","Octinoxate","g2","L3800-26","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","N/A","Others","Others","Octinoxate (Octyl methoxycinnamate, ethylhexyl methoxycinnamate) is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage.",{"v":290.4,"d":"290.40"},"5466-77-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/octinoxate.html","C18H26O3","free base","Octyl methoxycinnamate, ethylhexyl methoxycinnamate","CCCCC(CC)COC(=O)C=CC1=CC=C(OC)C=C1",5.153,3,0,10]
["S5326","Dolasetron","b3","L3800-26","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","Marketed","5-HT Receptor","Neuronal Signaling","Dolasetron(MDL-73147EF) is a highly specific and selective serotonin 5-HT3 receptor antagonist. It has minimal activity at other known serotonin receptors, and has low affinity for dopamine receptors.",324.37,"115956-12-2",{"v":64,"d":"64.00"},197.31,"<1","N/A","https://www.selleckchem.com/products/dolasetron.html","C19H20N2O3","free base","MDL-73147EF","O=C1CN2C3CC(CC2CC1C3)OC(=O)C4=C[NH]C5=C4C=CC=C5",2.035,3,1,3]
["S5333","Sulbenicillin Sodium","f3","L3800-26","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17","N/A","Antibiotics","Microbiology","Sulbenicillin Sodium (Sulfocillin, Sulfobenzylpenicillin) is the sodium salt of sulbenicillin, which is a penicillin antibiotic.",458.42,"28002-18-8",{"v":91,"d":"91.00"},198.51,{"v":91,"d":"91.00"},198.51,"http://selleckchem.com/products/sulbenicillin-sodium.html","C16H16N2O7S2.2Na","sodium salt","Sulfocillin, Sulfobenzylpenicillin","[Na+].[Na+].CC1(C)SC2C(NC(=O)C(C3=CC=CC=C3)[S]([O-])(=O)=O)C(=O)N2C1C([O-])=O",-3.303,2,1,5]
["S5343","Vanillic acid","a4","L3800-26","in 10mM DMSO","N/A","BP2010","N/A","NF-κB","NF-κB","Vanillic acid (4-hydroxy-3-methoxybenzoic acid) is a flavoring agent which is also an intermediate in the production of vanillin from ferulic acid. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects.",168.15,"121-34-6",{"v":33,"d":"33.00"},196.25,"N/A","N/A","http://selleckchem.com/products/vanillic-acid.html","C8H8O4","free base","4-hydroxy-3-methoxybenzoic acid","COC1=C(O)C=CC(=C1)C(O)=O",1.201,2,1,2]
["S5345","Nerolidol","b4","L3800-26","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Parasite","Microbiology","Nerolidol (Peruviol) is a naturally occurring sesquiterpene found in the essential oils of many types of plants and flowers. It has diverse range of pharmacological and biological activities including antioxidant, anti-microbial, anti-biofilm, anti-parasitic, insecticidal, anti-ulcer, skin penetration enhancer, anti-tumor, anti-nociceptive and anti-inflammatory properties.",222.37,"7212-44-4","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/nerolidol.html","C15H26O","free base","Peruviol","CC(C)=CCC/C(C)=C/CCC(C)(O)C=C",4.561,0,0,7]
["S5352","Cefminox Sodium","e4","L3800-26","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17","N/A","Bacterial","Microbiology","Cefminox Sodium (Meicelin, MT-141) is the sodium salt form of cefminox, a semi-synthetic, second-generation, beta-lactamase-stable cephalosporin with antibacterial activity.",541.56,"75498-96-3",{"v":100,"d":"100.00"},184.65,{"v":100,"d":"100.00"},184.65,"http://selleckchem.com/products/cefminox-sodium.html","C16H20N7O7S3.Na","sodium salt","Meicelin, MT-141","[Na+].COC1(NC(=O)CSCC(N)C(O)=O)C2SCC(=C(N2C1=O)C([O-])=O)CSC3=NN=N[N]3C",-5.601,7,2,11]
["S5357","Safinamide","h4","L3800-26","in 10mM DMSO","FDA,DMF,EMA,NDC","N/A","Marketed","MAO","Metabolism","Safinamide (EMD-1195686, PNU-15774E) is an orally active, selective, reversible <v>monoamine oxidase-B inhibitor with both dopaminergic and non-dopaminergic (glutamatergic) properties. The IC50 value of safinamide for MAO-B is 98 nM.",302.34,"133865-89-1",{"v":60,"d":"60.00"},198.45,{"v":-1,"d":"-1.00"},-3.31,"http://selleckchem.com/products/safinamide.html","C17H19FN2O2","free base","EMD-1195686, PNU-15774E","CC(NCC1=CC=C(OCC2=CC=CC(=C2)F)C=C1)C(N)=O",2.478,2,2,7]
["S5361","Bendazac","d5","L3800-26","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia","N/A","Immunology & Inflammation related","Immunology & Inflammation","Bendazac (bendazolic acid, AF-983) is a non-steroidal anti-inflammatory drug that delays the cataractogenic process. It may act by preventing protein denaturation.",282.29,"20187-55-7",{"v":56,"d":"56.00"},198.37,"<1","N/A","http://selleckchem.com/products/bendazac.html","C16H14N2O3","free base","bendazolic acid, AF-983","OC(=O)COC1=N[N](CC2=CC=CC=C2)C3=C1C=CC=C3",3.267,3,0,5]
["S5365","Alogliptin","f5","L3800-26","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","DPP","Proteases","Alogliptin is a potent, selective inhibitor of the serine protease dipeptidyl peptidase IV (DPP-4) with IC50 values of 2.63 nM and exhibits greater than 10,000 fold selectivity over the closely related serine proteases DPP-8 and DPP-9.",339.39,"850649-61-5",{"v":67,"d":"67.00"},197.41,{"v":18,"d":"18.00"},53.04,"http://selleckchem.com/products/alogliptin.html","C18H21N5O2","Dipeptidyl Peptidase-4","SYR 322","CN1C(=O)C=C(N2CCCC(N)C2)N(CC3=CC=CC=C3C#N)C1=O",1.271,2,1,3]
["S5368","Lactitol","a6","L3800-26","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8,KP Ⅹ,BP2015","Marketed","Others","Others","Lactitol is a versatile, reduced calorie sweetener derived from natural milk sugar, used in a wide variety of sweetening applications.",344.31,"585-86-4",{"v":68,"d":"68.00"},{"v":197.5,"d":"197.50"},"N/A","N/A","http://selleckchem.com/products/lactitol.html","C12H24O11","free base","N/A","OCC(O)C(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)CO",-4.688,2,9,8]
["S5377","Dibutyl phthalate","e6","L3800-26","in 10mM DMSO","N/A","EP9.2;BP2017;USP40-NF35;IP2010;Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Dibutyl phthalate is widely used as plasticizer in numerous kinds of products such as plastic packaging in food industries.",278.34,"84-74-2","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/dibutyl-phthalate.html","C16H22O4","free base","N/A","CCCCOC(=O)C1=C(C=CC=C1)C(=O)OCCCC",4.198,4,0,10]
["S5386","7-Dehydrocholesterol","h6","L3800-26","in 10mM DMSO","N/A","N/A","Marketed","Vitamin","Metabolism","7-Dehydrocholesterol (7-DHC, Provitamin D3) is the direct precursor of free cholesterol in the cholesterol biosynthetic pathway in mammalian tissues and also a biosynthetic precursor to vitamin D3.",384.64,"434-16-2",{"v":76,"d":"76.00"},197.59,{"v":-1,"d":"-1.00"},{"v":-2.6,"d":"-2.60"},"https://www.selleckchem.com/products/7-dehydrocholesterol.html","C27H44O","free base","7-DHC, Provitamin D3","CC(C)CCCC(C)C1CCC2C3=CC=C4CC(O)CCC4(C)C3CCC12C",7.126,0,1,5]
["S5388","Betrixaban","a7","L3800-26","in 10mM DMSO","FDA,EMA,NDC","N/A","Marketed","Factor Xa","Metabolism","Betrixaban is a new, long-acting, oral and selective Factor Xa inhibitor that decreases prothrombinase activity and thrombin generation.",451.91,"330942-05-7",{"v":35,"d":"35.00"},77.45,"<1","N/A","https://www.selleckchem.com/products/betrixaban.html","C23H22ClN5O3","free base","PRT054021","COC1=CC=C(NC(=O)C2=CC=C(C=C2)C(=N)N(C)C)C(=C1)C(=O)NC3=CC=C(Cl)C=N3",2.904,4,2,7]
["S5393","Cyclofenil","d7","L3800-26","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia","N/A","Estrogen/progestogen Receptor","Endocrinology & Hormones","Cyclofenil is a selective estrogen receptor modulator showing a higher affinity for ERβ than Erα.",364.43,"2624-43-3",{"v":21,"d":"21.00"},57.62,"N/A","N/A","https://www.selleckchem.com/products/cyclofenil.html","C23H24O4","free base","F-6066; H-3452","CC(=O)OC1=CC=C(C=C1)[C](=[C]2CC[CH2]CC2)C3=CC=C(OC(C)=O)C=C3",5.241,4,0,6]
["S5397","Chlorhexidine","g7","L3800-26","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,KP Ⅹ,Ph.Int_6th,BP2017,JP17,IP2010","Marketed","Anti-infection","Microbiology","Chlorhexidine is a disinfectant and topical anti-infective agent that is active against Gram-positive and Gram-negative organisms, facultative anaerobes, aerobes, and yeasts.",505.45,"55-56-1",{"v":100,"d":"100.00"},197.84,{"v":-1,"d":"-1.00"},-1.98,"https://www.selleckchem.com/products/chlorhexidine.html","C22H30Cl2N10","free base","N/A","ClC1=CC=C(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC2=CC=C(Cl)C=C2)C=C1",4.373,0,6,17]
["S5402","Dasabuvir (ABT-333)","c8","L3800-26","in 10mM DMSO","FDA,EMA,NDC","N/A","Marketed","HCV Protease","Proteases","Dasabuvir (ABT-333) is a non-nucleoside inhibitor of NS5B viral RNA-dependent RNA polymerase that inhibits recombinant NS5B polymerases derived from HCV genotype 1a and 1b clinical isolates with IC50 values between 2.2 and 10.7 nM. It is at least 7,000-fold selective for the inhibition of HCV genotype 1 polymerases over human/mammalian polymerases.",493.57,"1132935-63-7",{"v":98,"d":"98.00"},198.55,"<1","N/A","http://selleckchem.com/products/dasabuvir-abt-333.html","C26H27N3O5S","free base","N/A","COC1=C(C=C(C=C1C2=CC3=CC=C(N[S](C)(=O)=O)C=C3C=C2)N4C=CC(=O)NC4=O)C(C)(C)C",3.492,5,2,6]
["S5405","Propylparaben","f8","L3800-26","in 10mM DMSO","N/A","USP41-NF36;BP2015;IP2010","N/A","Anti-infection","Microbiology","Propylparaben (Propyl 4-hydroxybenzoate, Propyl p-hydroxybenzoate, nipasol), a natural substance found in many plants and some insects, is an antimicrobial, preservative and flavouring agent.",{"v":180.2,"d":"180.20"},"94-13-3",{"v":36,"d":"36.00"},199.78,"<1","N/A","https://www.selleckchem.com/products/propylparaben.html","C10H12O3","Benzoate esters","Propyl 4-hydroxybenzoate, 4-Hydroxybenzoic acid propyl ester, Propyl p-hydroxybenzoate, nipasol","CCCOC(=O)C1=CC=C(O)C=C1",2.315,2,1,4]
["S5410","Chloramphenicol sodium succinate","a9","L3800-26","in 10mM DMSO","FDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,BP2017,Ph.Int_5th,USP39-NF34,JP16,IP2010","Marketed","Antibiotics,Bacterial","Microbiology","Chloramphenicol Sodium Succinate is the sodium succinate salt form of chloramphenicol, a nitrobenzene derivate and broad-spectrum antibiotic with antibacterial activity.",445.18,"982-57-0",{"v":89,"d":"89.00"},199.92,"N/A","N/A","http://selleckchem.com/products/chloramphenicol-sodium-succinate.html","C15H15Cl2N2O8.Na","sodium salt","N/A","[Na+].OC(C(COC(=O)CCC([O-])=O)NC(=O)C(Cl)Cl)C1=CC=C(C=C1)[N+]([O-])=O",-0.225,3,2,11]
["S5416","Metyrapone","e9","L3800-26","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,JP17,BP2017,","Marketed","P450 (e.g. CYP17)","Metabolism","Metyrapone (NSC-25265, SU-4885) is an inhibitor of the enzyme steroid 11-beta-monooxygenase (CYP11B1) that inhibits adrenal steroid synthesis.",226.27,"54-36-4",{"v":46,"d":"46.00"},203.29,{"v":-1,"d":"-1.00"},-4.42,"https://www.selleckchem.com/products/metyrapone.html","C14H14N2O","free base","NSC-25265, SU-4885","CC(C)(C1=CC=CN=C1)C(=O)C2=CC=CN=C2",1.847,3,0,3]
["S5420","Clindamycin alcoholate","h9","L3800-26","in 10mM DMSO","FDA,DMF,CFDA,NDC,HMA","N/A","Marketed","Antibiotics,Bacterial","Microbiology","Clindamycin alcoholate is a crystallizable compound of Clindamycin with alcohol. Clindamycin is a semisynthetic lincosamide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.",479.46,"58207-19-5",{"v":95,"d":"95.00"},198.14,"N/A","N/A","http://selleckchem.com/products/clindamycin-alcoholate.html","C18H33ClN2O5S.HCl.H2O","hydrochloride, monohydrate","N/A","O.Cl.CCCC1CC(N(C)C1)C(=O)NC(C(C)Cl)C2OC(SC)C(O)C(O)C2O",1.451,2,4,7]
["S5424","Carbaryl","a10","L3800-26","in 10mM DMSO","N/A","BP2019;Martindale:The Extra Pharmacopoeia","N/A","AChR","Neuronal Signaling","Carbaryl (1-naphthyl methylcarbamate) is a carbamate insecticide and parasiticide and also a potent anticholinesterase agent belonging to the carbamate group of reversible cholinesterase inhibitors.",201.22,"63-25-2",{"v":40,"d":"40.00"},198.79,"N/A","N/A","http://selleckchem.com/products/carbaryl.html","C12H11NO2","free base","1-naphthyl methylcarbamate","CNC(=O)OC1=C2C=CC=CC2=CC=C1",2.502,2,1,2]
["S5435","Quinacrine Dihydrochloride Dihydrate","d10","L3800-26","in 10mM DMSO","DMF","N/A","Phase 2","Others","Others","Quinacrine (Mepacrine) is a dye of the acridine family that has been widely used as staining agents for DNA and model compounds for intercalators in numerous biophysical studies. It is also an antimalarial drug.",508.91,"6151-30-0",{"v":10,"d":"10.00"},19.65,"N/A","N/A","http://selleckchem.com/products/quinacrine-dihydrochloride-dihydrate.html","C23H30ClN3O.2HCl.2H2O","dihydrochloride, dihydrate","Mepacrine Dihydrochloride Dihydrate","O.O.Cl.Cl.CCN(CC)CCCC(C)NC1=C2C=C(OC)C=CC2=NC3=CC(=CC=C13)Cl",6.015,2,1,9]
["S5450","Sofalcone","g10","L3800-26","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Sofalcone (SU-88) is an antiulcer drug and a mucosal protective agent, increasing vascular endothelual growth factor via the Nrf2-heme-oxygenase-1 dependent pathway in gastric epithelial cells.",450.52,"64506-49-6",{"v":90,"d":"90.00"},199.77,{"v":-1,"d":"-1.00"},-2.22,"https://www.selleckchem.com/products/sofalcone.html","C27H30O6","free base","SU-88","CC(C)=CCOC1=CC=C(/C=C/C(=O)C2=C(OCC(O)=O)C=C(OCC=C(C)C)C=C2)C=C1",6.065,5,0,12]
["S5459","Aucubin","e11","L3800-26","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Immunology & Inflammation related","Immunology & Inflammation","Aucubin (Rhinanthin), an iridoid glycoside existing in medicinal plants, has been reported to show an anti-inflammatory activity by suppression of TNF-α production in murine macrophages.",346.33,"479-98-1",{"v":69,"d":"69.00"},199.23,{"v":15,"d":"15.00"},43.31,"http://selleckchem.com/products/aucubin.html","C15H22O9","free base","Rhinanthin","OCC1OC(OC2OC=CC3C(O)C=C(CO)C23)C(O)C(O)C1O",-2.916,3,6,4]
["S5473","Pivmecillinam hydrochloride","h11","L3800-26","in 10mM DMSO","marketed in the Nordic countries","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,JP17,BP2017","N/A","Antibiotics,Bacterial","Microbiology","Pivmecillinam is a β-lactam antibiotic and a prodrug of mecillinam. It has selective activity against Gram-negative bacteria and is used primarily in the treatment of lower urinary tract infections.",476.03,"32887-03-9",{"v":95,"d":"95.00"},199.57,{"v":95,"d":"95.00"},199.57,"http://selleckchem.com/products/pivmecillinam-hydrochloride.html","C21H33N3O5S.HCl","hydrochloride","N/A","Cl.CC(C)(C)C(=O)OCOC(=O)C1N2C(SC1(C)C)C(N=CN3CCCCCC3)C2=O",3.161,6,0,8]
["S5479","Cloperastine hydrochloride","d2","L3800-27","in 10mM DMSO","CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17","N/A","Histamine Receptor","Neuronal Signaling","Cloperastine (HT-11) is a drug with a central antitussive effect, and is also endowed with an antihistaminic activity.",366.32,"14984-68-0",{"v":73,"d":"73.00"},199.28,"N/A","N/A","http://selleckchem.com/products/cloperastine-hydrochloride.html","C20H24ClNO.HCl","hydrochloride","HT-11 hydrochloride","Cl.ClC1=CC=C(C=C1)C(OCCN2CCCCC2)C3=CC=CC=C3",5.348,1,0,6]
["S5482","Prilocaine hydrochloride","g2","L3800-27","in 10mM DMSO","FDA,NDC,DMF,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,BP2017","Marketed","Others","Others","Prilocaine hydrochloride is the hydrochloride salt form of prilocaine, which is a local anesthetic.",256.77,"1786-81-8",{"v":51,"d":"51.00"},198.62,"N/A","N/A","https://www.selleckchem.com/products/prilocaine-hydrochloride.html","C13H20N2O.HCl","hydrochloride","N/A","Cl.CCCNC(C)C(=O)NC1=CC=CC=C1C",2.645,1,2,5]
["S5485","Desipramine Hydrochloride","b3","L3800-27","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","Phase 4","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Desipramine hydrochloride (Desmethylimipramine, Norimipramine, EX-4355, G-35020, JB-8181, NSC-114901) is a dibenzazepine-derivative tricyclic antidepressant that acts as a selective norepinephrine reuptake inhibitor. It also shows weak serotonin reuptake inhibitory, α1-blocking, antihistamine, and anticholinergic effects.",302.84,"58-28-6",{"v":60,"d":"60.00"},198.12,"N/A","N/A","http://selleckchem.com/products/desipramine-hydrochloride.html","C18H22N2.HCl","hydrochloride","Desmethylimipramine, Norimipramine, EX-4355, G-35020, JB-8181, NSC-114901","Cl.CNCCCN1C2=C(CCC3=C1C=CC=C3)C=CC=C2",4.234,0,1,4]
["S5486","Fluorometholone","c3","L3800-27","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,JP17,BP2017","Phase 4","Glucocorticoid Receptor","Endocrinology & Hormones","Fluorometholone (Oxylone) is a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. It is usually used as eye drops in the treatment of allergic and inflammatory conditions of the eye.",376.46,"426-13-1",{"v":75,"d":"75.00"},199.22,"<1","N/A","http://selleckchem.com/products/fluorometholone.html","C22H29FO4","free base","Oxylone","CC1CC2C3CCC(O)(C(C)=O)C3(C)CC(O)C2(F)C4(C)C=CC(=O)C=C14",2.312,2,1,1]
["S5488","Fluorescein","e3","L3800-27","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,Ph.Int_6th,JP17,BP2017,IP2010","Phase 3","Dyes","Others","Fluorescein (Solvent Yellow 94, Resorcinolphthalein, Yellow fluorescein) is a manufactured organic compound and dye.",332.31,"2321-07-5",{"v":67,"d":"67.00"},201.62,{"v":-1,"d":"-1.00"},-3.01,"https://www.selleckchem.com/products/fluorescein.html","C20H12O5","free base","Solvent Yellow 94, Resorcinolphthalein, Yellow fluorescein","OC1=CC2=C(C=C1)C3(OC(=O)C4=C3C=CC=C4)C5=C(O2)C=C(O)C=C5",3.737,3,2,0]
["S5492","Econazole","h3","L3800-27","in 10mM DMSO","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017,IP2010","Marketed","Bacterial","Microbiology","Econazole is a broad spectrum antimycotic with some action against Gram positive bacteria.",381.68,"27220-47-9",{"v":76,"d":"76.00"},199.12,"N/A","N/A","http://selleckchem.com/products/econazole.html","C18H15Cl3N2O","free base","N/A","ClC1=CC=C(COC(C[N]2C=CN=C2)C3=C(Cl)C=C(Cl)C=C3)C=C1",4.981,2,0,6]
["S5498","Betahistine mesylate","d4","L3800-27","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,IP2010,BP2017","Marketed","Histamine Receptor","Neuronal Signaling","Betahistine mesylate is the mesylate salt form of Betahistine, a histamine analog and H3 receptor agonist that serves as a vasodilator.",328.41,"54856-23-4",{"v":65,"d":"65.00"},197.92,"N/A","N/A","http://selleckchem.com/products/betahistine-mesylate.html","C8H12N2.2CH4O3S","dimethanesulfonate","N/A","CNCCC1=CC=CC=N1.C[S](O)(=O)=O.C[S](O)(=O)=O",-0.148,1,1,3]
["S5502","Ilaprazole sodium","g4","L3800-27","in 10mM DMSO","CFDA","N/A","Marketed","ATPase,Proton Pump","Transmembrane Transporters","Ilaprazole (IY-81149) sodium is the sodium salt form of ilaprazole, which is a proton pump inhibitor. Ilaprazole sodium irreversibly inhibits H(+)/K(+)-ATPase in a dose-dependent manner with IC50 of 6 μM in rabbit parietal cell preparation.",388.42,"172152-50-0",{"v":78,"d":"78.00"},200.81,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/iiaprazole-sodium.html","C19H17N4NaO2S","Sodium Salt","IY-81149 sodium","COC1=C(C)C(=NC=C1)C[S](=O)C2=NC3=C(C=CC(=C3)[N]4C=CC=C4)[N]2[Na]",3.414,4,0,5]
["S5507","Trimebutine maleate","c5","L3800-27","in 10mM DMSO","DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,EP9.3,KP Ⅹ,JP17,BP2017","N/A","Opioid Receptor","Neuronal Signaling","Trimebutine maleate is the maleate salt form of trimebutine, which is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects.",503.54,"34140-59-5",{"v":100,"d":"100.00"},198.59,{"v":-1,"d":"-1.00"},-1.99,"https://www.selleckchem.com/products/trimebutine-maleate.html","C26H33NO9","Maleate salt","3, 4, 5-Trimethoxybenzoic Acid 2-(Dimethylamino)-2-phenylbutyl Ester Maleate Salt;","CCC(COC(=O)C1=CC(=C(OC)C(=C1)OC)OC)(N(C)C)C2=CC=CC=C2.OC(=O)\\C=C/C(O)=O",{"v":1.12,"d":"1.120"},7,0,12]
["S5527","Salmeterol","f5","L3800-27","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","Phase 3","Adrenergic Receptor","Neuronal Signaling","Salmeterol (Astmerole, GR-33343X, SN408D) is a long-acting beta2-adrenergic receptor agonist with Ki value of 1.5 nM for WT β2AR and shows very high selectivity for the WT β2AR(β1Ki/β2Ki ratio of approximately 1500).",415.57,"89365-50-4",{"v":83,"d":"83.00"},199.73,"<1","N/A","http://selleckchem.com/products/salmeterol.html","C25H37NO4","free base","Astmerole, GR-33343X, SN408D","OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC2=CC=CC=C2",4.251,1,4,16]
["S5531","Doripenem","a6","L3800-27","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics","Microbiology","Doripenem(S 4661) is a new parenteral carbapenem antibiotic with broad-spectrum activity against gram-negative and gram-positive pathogens.",{"v":420.5,"d":"420.50"},"148016-81-3",{"v":60,"d":"60.00"},142.69,{"v":-1,"d":"-1.00"},-2.38,"https://www.selleckchem.com/products/doripenem.html","C15H24N4O6S2","free base","S 4661","CC(O)C1C2C(C)C(=C(N2C1=O)C(O)=O)SC3CNC(CN[S](N)(=O)=O)C3",-5.339,4,4,7]
["S5532","Erythromycin estolate","b6","L3800-27","in 10mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,BP2017","Registered","Bacterial","Microbiology","Erythromycin (Lubomycine B), a naturally occurring macrolide, is derived from Streptomyces erythrus. It inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.",1056.39,"3521-62-8",{"v":100,"d":"100.00"},94.66,{"v":-1,"d":"-1.00"},-0.95,"https://www.selleckchem.com/products/erythromycin-estolate.html","C52H97NO18S","free base","Lubomycine B","CCCCCCCCCCCCO[S](O)(=O)=O.CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3OC(=O)CC)N(C)C)C(C)(O)CC(C)C(=O)C(C)C(O)C1(C)O",7.248,11,2,22]
["S5538","Tropisetron","e6","L3800-27","in 10mM DMSO","CFDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017","Marketed","5-HT Receptor,AChR","Neuronal Signaling","Tropisetron (ICS 205-930) is a 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.",284.35,"89565-68-4",{"v":10,"d":"10.00"},35.17,{"v":56,"d":"56.00"},196.94,"http://selleckchem.com/products/tropisetron.html","C17H20N2O2","free base","ICS 205-930","CN1C2CCC1CC(C2)OC(=O)C3=C[NH]C4=C3C=CC=C4",2.608,2,1,3]
["S5543","1, 10-Phenanthroline monohydrate","a7","L3800-27","in 10mM DMSO","N/A","IP2010;USP42-NF37","N/A","MMP","Proteases","1,10-Phenanthroline is a classic chelating bidentate ligand for transition metal ions that has played an important role in the development of coordination chemistry. It is an inhibitor of metallopeptidases.",198.22,"5144-89-8",{"v":39,"d":"39.00"},196.75,"N/A","N/A","http://selleckchem.com/products/1-10-phenanthroline-monohydrate.html","C12H8N2.H2O","hydrate","Phenanthroline monohydrate","O.C1=CC2=C(N=C1)C3=C(C=CC=N3)C=C2",1.995,2,0,0]
["S5547","Hydroxylammonium chloride","d7","L3800-27","in 10mM DMSO","N/A","IP2010","N/A","Others","Others","Hydroxylammonium chloride (Hydroxylamine hydrochloride) is the hydrochloric acid salt of hydroxylamine, which is a biological intermediate in the nitrification and in the anammox.",69.46,"5470-11-1","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/hydroxylammonium-chloride.html","HCl.H3NO","chloride","Hydroxylamine hydrochloride","Cl.NO",-0.305,0,1,0]
["S5553","Kasugamycin hydrochloride","g7","L3800-27","in 10mM DMSO","CFDA","N/A","N/A","Antineoplastic and Immunosuppressive Antibiotics,Fungal,Selection Antibiotics for Transfected Cell","Microbiology","Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.",415.82,"19408-46-9","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/kasugamycin-hydrochloride.html","C14H25N3O9.HCl","hydrochloride","N/A","Cl.CC1OC(OC2C(O)C(O)C(O)C(O)C2O)C(N)CC1NC(=N)C(O)=O",-6.175,3,7,5]
["S5558","D-Pantothenate Sodium","c8","L3800-27","in 10mM DMSO","NDC","N/A","N/A","Vitamin","Metabolism","D-Pantothenate Sodium, the sodium salt of D-pantothenate, is a derivative of vitamin B5 which is an an essential nutrient and plays important roles in the oxidation of fats and carbohydrates and certain amino acids.",241.22,"867-81-2",{"v":6,"d":"6.00"},24.87,"N/A","N/A","http://selleckchem.com/products/d-pantothenate-sodium.html","C9H16NO5.Na","sodium salt","N/A","[Na+].CC(C)(CO)C(O)C(=O)NCCC([O-])=O",-2.533,1,3,6]
["S5561","Ethacrynic Acid","f8","L3800-27","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37,IP2010","Phase 3","Others","NF-κB","Ethacrynic Acid is a loop or high ceiling diuretic used for the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.",303.14,"58-54-8",{"v":61,"d":"61.00"},201.23,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/ethacrynic-acid.html","C13H12Cl2O4","Free Base","N/A","CCC(=C)C(=O)C1=C(Cl)C(=C(OCC(O)=O)C=C1)Cl",3.963,3,0,6]
["S5564","Xylazine","a9","L3800-27","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017","N/A","Adrenergic Receptor","Neuronal Signaling","Xylazine is a partial alpha-2 adrenergic agonist that is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals.",220.33,"7361-61-7",{"v":44,"d":"44.00"},{"v":199.7,"d":"199.70"},{"v":-1,"d":"-1.00"},-4.54,"https://www.selleckchem.com/products/xylazine.html","C12H16N2S","free base","N/A","CC1=C(NC2=NCCCS2)C(=CC=C1)C",3.265,1,1,2]
["S5565","Triflupromazine hydrochloride","b9","L3800-27","in 10mM DMSO","FDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,IP2010","N/A","Dopamine Receptor","Neuronal Signaling","Triflupromazine hydrochloride (Fluopromazine) is an antipsychotic medication of the phenothiazine class.",388.88,"1098-60-8",{"v":78,"d":"78.00"},200.58,"N/A","N/A","https://www.selleckchem.com/products/triflupromazine-hydrochloride.html","C18H20ClF3N2S","salt","Fluopromazine hydrochloride","Cl.CN(C)CCCN1C2=C(SC3=CC=C(C=C13)C(F)(F)F)C=CC=C2",5.399,0,0,5]
["S5568","Tocofersolan","e9","L3800-27","in 10mM DMSO","EMA","N/A","Marketed","Vitamin","Metabolism","Tocofersolan (Tocophersolan) is a synthetic water-soluble version of vitamin E that is used in treatment of vitamin E deficiency.",574.83,"9002-96-4",{"v":100,"d":"100.00"},173.96,{"v":-1,"d":"-1.00"},-1.74,"https://www.selleckchem.com/products/tocofersolan.html","(C2H4O)nC33H54O5","free base","Tocophersolan","CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=C(C)C(=C(C)C(=C2O1)C)OC(=O)CCC(=O)OCCO",10.716,5,1,20]
["S5581","Olmesartan","a10","L3800-27","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","N/A","Marketed","Angiotensin Receptor","GPCR & G Protein","Olmesartan (RNH-6270) is an an angiotensin 2 receptor antagonist with antihypertensive activity.",{"v":446.5,"d":"446.50"},"144689-24-7",{"v":89,"d":"89.00"},199.33,{"v":-1,"d":"-1.00"},-2.24,"https://www.selleckchem.com/products/olmesartan.html","C24H26N6O3","free base","RNH-6270","CCCC1=NC(=C([N]1CC2=CC=C(C=C2)C3=C(C=CC=C3)C4=NN=N[NH]4)C(O)=O)C(C)(C)O",3.766,5,1,8]
["S5585","Citronellal","d10","L3800-27","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Others","Others","Citronellal (Rhodinal, 2,3-Dihydrocitral), a monoterpenoid found in oil of citronella, lemon, and lemon grass, has insect repellent properties and is used in perfumes.",154.25,"106-23-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","https://www.selleckchem.com/products/citronellal-rhodinal.html","C10H18O","free base","Rhodinal; 2,3-Dihydrocitral","CC(CCC=C(C)C)CC=O",3.018,1,0,5]
["S5594","α-Terpineol","f10","L3800-27","in 10mM DMSO","N/A","BP2019","N/A","Prostaglandin Receptor","GPCR & G Protein","α-Terpineol, a natural monoterpene, is the major component of essential oils of several species of aromatic plants such as Origanium vulgare L. and Ocimum canum Sims which are widely used for medicinal purposes. It is widely used in the manufacturing of cosmetics, soaps, perfumes, antiseptic agents and is considered one of the most frequently used fragrance compounds. α-TPN has anticholinergic action and can block the interaction between PGE2 and GM1 receptors and cholera toxin.",154.25,"10482-56-1","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://selleckchem.com/products/alpha-terpineol.html","C10H18O","free base","N/A","CC1=CCC(CC1)C(C)(C)O",2.415,0,0,1]
["S5604","Diphenylamine Hydrochloride","b11","L3800-27","in 10mM DMSO","N/A","BP2016;USP36-NF31;IP2010","N/A","OXPHOS","Apoptosis","Diphenylamine (N-Phenylbenzenamine, Anilinobenzene, C.I. 10355), a derivative of aniline, is widely used as an industrial antioxidant, dye mordant and reagent and is also employed in agriculture as a fungicide and antihelmintic. Diphenylamine can inhibits oxidative phosphorylationsignificantly, although its inhibition potency was weaker than that of NSAIDs with a diphenylamine structure.",205.68,"537-67-7",{"v":41,"d":"41.00"},199.34,{"v":1,"d":"1.00"},4.86,"http://www.selleckchem.com/products/diphenylamine-hydrochloride.html","C12H12ClN","Hydrochloride","N-Phenylbenzenamine, Anilinobenzene, C.I. 10355","Cl.N(C1=CC=CC=C1)C2=CC=CC=C2",3.762,0,1,2]
["S5619","Betahistine","e11","L3800-27","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","N/A","Histamine Receptor","Neuronal Signaling","Betahistine is an antivertigo drug that primarily acts as a histamine H1 agonist.",136.19,"5638-76-6","The physical form of the compound is liquid, which can be dissolved in any proportion.",{"v":10,"d":"10.00"},"N/A",{"v":0,"d":"0.00"},"https://www.selleckchem.com/products/betahistine.html","C8H12N2","free base","N/A","CNCCC1=NC=CC=C1",{"v":0.68,"d":"0.680"},1,1,3]
["S5623","Bedaquiline","h11","L3800-27","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","ATPase","Transmembrane Transporters","Bedaquiline (TMC-207, R207910), a diarylquinoline, binds to subunit c of mycobacterial ATP synthase and inhibits its activity. It is highly selective for mycobacterial ATP synthase enzyme compared to homologous eukaryotic enzyme (Selectivity Index >20 000).",{"v":555.5,"d":"555.50"},"843663-66-1",{"v":12,"d":"12.00"},{"v":21.6,"d":"21.60"},"<1","N/A","https://www.selleckchem.com/products/bedaquiline.html","C32H31BrN2O2","free base","TMC-207, R207910","COC1=NC2=CC=C(Br)C=C2C=C1C(C3=CC=CC=C3)C(O)(CCN(C)C)C4=CC=CC5=CC=CC=C45",6.933,2,0,8]
["S5625","Ammonium lactate","a2","L3800-28","in 10mM DMSO","FDA,NDC,DMF","Martindale:The Extra Pharmacopoeia","Marketed","Bacterial","Microbiology","Ammonium lactate (Lac-hydrin) is the ammonium salt of lactic acid with mild anti-bacterial properties.",107.11,"515-98-0","The physical form of the compound is liquid, which can be dissolved in any proportion.",{"v":10,"d":"10.00"},"N/A",{"v":0,"d":"0.00"},"https://www.selleckchem.com/products/ammonium-iactate.html","C3H9NO3","free base","Lac-hydrin","[NH4+].CC(O)C([O-])=O",-3.725,0,1,1]
["S5637","Cefotiam Hexetil Hydrochloride","d2","L3800-28","in 10mM DMSO","PMDA","KP Ⅹ,JP17","N/A","Antibiotics,Bacterial","Microbiology","Cefotiam Hexetil Hydrochloride is the hydrochloride salt of cefotiam hexetil. Cefotiam is a semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity.",768.76,"95789-30-3",{"v":100,"d":"100.00"},130.08,{"v":-1,"d":"-1.00"},{"v":-1.3,"d":"-1.30"},"https://www.selleckchem.com/products/cefotiam-hexetil-hydrochloride.html","C27H39Cl2N9O7S3","free base","N/A","Cl.Cl.CC(OC(=O)OC1CCCCC1)OC(=O)C2=C(CSC3C(NC(=O)CC4=CSC(=N4)N)C(=O)N23)CSC5=NN=N[N]5CCN(C)C",2.966,11,2,16]
["S5648","Iguratimod","h2","L3800-28","in 10mM DMSO","CFDA,PMDA","N/A","Marketed","Immunology & Inflammation related","Immunology & Inflammation","Iguratimod (T-614) is a small molecule compound with anti-inflammatory and immunomodulatory actions and used for the treatment of rheumatoid arthritis.",374.37,"123663-49-0",{"v":50,"d":"50.00"},133.56,"N/A","N/A","http://selleckchem.com/products/iguratimod.html","C17H14N2O6S","free base","T-614","C[S](=O)(=O)NC1=CC2=C(C=C1OC3=CC=CC=C3)C(=O)C(=CO2)NC=O",0.605,6,2,5]
["S5652","Elbasvir","c3","L3800-28","in 10mM DMSO","FDA,EMA,NDC,PMDA","N/A","Phase 2","HCV Protease","Proteases","Elbasvir (MK8742) is an NS5A inhibitor, preventing hepatitis C viral RNA replication and virion assembly. Median EC50 values range from 0.2 to 3600 pmol/L, based on genotype.",882.02,"1370468-36-2",{"v":100,"d":"100.00"},113.38,"<1","N/A","http://selleckchem.com/products/elbasvir.html","C49H55N9O7","free base","MK8742","COC(=O)NC(C(C)C)C(=O)N1CCCC1C2=NC=C([NH]2)C3=CC4=C(C=C3)C5=CC6=C(C=CC(=C6)C7=CN=C([NH]7)C8CCCN8C(=O)C(NC(=O)OC)C(C)C)[N]5C(O4)C9=CC=CC=C9",7.424,9,4,13]
["S5655","Venlafaxine","f3","L3800-28","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","Marketed","Serotonin Transporter","Neuronal Signaling","Venlafaxine (Wy 45030) is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.",{"v":277.4,"d":"277.40"},"93413-69-5",{"v":55,"d":"55.00"},198.27,"<1","N/A","http://selleckchem.com/products/venlafaxine.html","C17H27NO2","Phenethylamine","Wy 45030","COC1=CC=C(C=C1)C(CN(C)C)C2(O)CCCCC2",3.022,1,0,5]
["S5659","Emedastine","b4","L3800-28","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,BP2017","Marketed","Histamine Receptor","Neuronal Signaling","Emedastine is a potent, high affinity histamine H1-receptor-selective antagonist with Ki of 1.3 ±0.1 nM for H1-receptors while considerably weaker at H2- (K1 = 49,067 ± 11,113 nM) and H3-receptors (Ki = 12,430 ± 1,282 nM).",302.41,"87233-61-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",{"v":10,"d":"10.00"},"N/A","N/A","http://selleckchem.com/products/emedastine.html","C17H26N4O","free base","N/A","CCOCC[N]1C2=C(C=CC=C2)N=C1N3CCCN(C)CC3",2.492,2,0,5]
["S5663","Minaprine dihydrochloride","e4","L3800-28","in 10mM DMSO","DMF","N/A","N/A","MAO","Metabolism","Minaprine dihydrochloride is hydrochloride salt form of Minaprine, which acts as a reversible inhibitor of MAO-A in rats and weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.",{"v":371.3,"d":"371.30"},"25905-77-5",{"v":74,"d":"74.00"},{"v":199.3,"d":"199.30"},{"v":74,"d":"74.00"},{"v":199.3,"d":"199.30"},"https://www.selleckchem.com/products/minaprine-dihydrochloride.html","C17H24Cl2N4O","free base","N/A","Cl.Cl.CC1=CC(=NN=C1NCCN2CCOCC2)C3=CC=CC=C3",3.583,3,1,5]
["S5664","Orphenadrine Hydrochloride","f4","L3800-28","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,BP2017,IP2010","Phase 3","NMDAR","Neuronal Signaling","Orphenadrine Hydrochloride is an uncompetitive NMDAR antagonist, H1 receptor antagonist and nonselective mAChR antagonist with muscle relaxant activity.",305.84,"341-69-5",{"v":61,"d":"61.00"},199.45,{"v":-1,"d":"-1.00"},-3.27,"https://www.selleckchem.com/products/orphenadrine-hydrochloride.html","C18H24ClNO","free base","N/A","Cl.CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2C",4.253,1,0,6]
["S5667","Fruquintinib (HMPL-013)","a5","L3800-28","in 10mM DMSO","CFDA","N/A","Marketed","VEGFR","Angiogenesis","Fruquintinib (HMPL-013) is a small molecule inhibitor with strong potency and high selectivity against VEGFR family. It inhibits VEGFR 1, 2, 3, with IC50 values of 33 nM, 35 nM and 0.5 nM, respectively and shows only weak inhibition of RET, FGFR-1 and c-kit kinases.",393.39,"1194506-26-7",{"v":6,"d":"6.00"},15.25,"<1","N/A","https://www.selleckchem.com/products/fruquintinib.html","C21H19N3O5","Tyrosine kinase inhibitor","N/A","CNC(=O)C1=C(C)OC2=CC(=CC=C12)OC3=C4C=C(OC)C(=CC4=NC=N3)OC",3.111,7,1,5]
["S5673","Mivacurium chloride","d5","L3800-28","in 10mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia","Phase 4","Others","Others","Mivacurium chloride is a rapid, non-depolarising, neuromuscular blocking agent of short duration, used therefore as anesthetic, to provide skeletal muscle relaxation in minor surgical operations, in emergency surgical procedures of short to intermediate duration and during intubation of the trachea.",1100.17,"106861-44-3",{"v":100,"d":"100.00"},{"v":90.9,"d":"90.90"},{"v":100,"d":"100.00"},{"v":90.9,"d":"90.90"},"http://www.selleckchem.com/products/mivacurium-chloride.html","C58H80Cl2N2O14","chloride","N/A","[Cl-].[Cl-].COC1=CC2=C(C=C1OC)C(CC3=CC(=C(OC)C(=C3)OC)OC)[N+](C)(CCCOC(=O)CC\\C=C\\CCC(=O)OCCC[N+]4(C)CCC5=C(C=C(OC)C(=C5)OC)C4CC6=CC(=C(OC)C(=C6)OC)OC)CC2",0.836,14,0,30]
["S5683","Isoproterenol sulfate dihydrate","h5","L3800-28","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","N/A","Adrenergic Receptor","Neuronal Signaling","Isoproterenol Sulfate is the sulfate salt form of isoproterenol, a beta-adrenergic receptor agonist with bronchodilator activity.",556.62,"299-95-6",{"v":100,"d":"100.00"},179.66,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/isoproterenol-sulfate-dihydrate.html","C22H40N2O12S","dihydrate","N/A","O.O.CC(C)NCC(O)C1=CC=C(O)C(=C1)O.CC(C)NCC(O)C2=CC=C(O)C(=C2)O.O[S](O)(=O)=O",1.177,0,8,8]
["S5693","Levomilnacipran Hydrochloride","c6","L3800-28","in 10mM DMSO","FDA,DMF,NDC","N/A","Marketed","Serotonin Transporter","Neuronal Signaling","Levomilnacipran Hydrochloride is a selective serotonin and norepinephrine reuptake inhibitor with antidepressant activity.",282.81,"175131-60-9",{"v":57,"d":"57.00"},201.55,{"v":57,"d":"57.00"},201.55,"http://www.selleckchem.com/products/levomilnacipran-hydrochloride.html","C15H23ClN2O","Hydrochloride","N/A","Cl.CCN(CC)C(=O)C1(CC1CN)C2=CC=CC=C2",{"v":1.67,"d":"1.670"},1,1,5]
["S5700","Phthalylsulfathiazole","f6","L3800-28","in 10mM DMSO","N/A","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Anti-infection","Microbiology","Phthalylsulfathiazole (Sulfathalidine) is a broad-spectrum antimicrobial that can treat different types of infections including intestinal.",403.43,"85-73-4",{"v":80,"d":"80.00"},{"v":198.3,"d":"198.30"},{"v":-1,"d":"-1.00"},-2.48,"https://www.selleckchem.com/products/phthalylsulfathiazole.html","C17H13N3O5S2","free base","Sulfathalidine","OC(=O)C1=C(C=CC=C1)C(=O)NC2=CC=C(C=C2)[S](=O)(=O)NC3=NC=CS3",1.729,5,2,6]
["S5705","Raceanisodamine","b7","L3800-28","in 10mM DMSO","CFDA","N/A","N/A","Others","Others","Raceanisodamine (7β-Hydroxyhyoscyamine) is the active ingredient of Chinese herbal extracts that has vasoactive activity used to treat acute disseminated intravascular coagulation in patients in bacteremic shock.",305.37,"17659-49-3",{"v":61,"d":"61.00"},199.76,{"v":30,"d":"30.00"},98.24,"http://selleckchem.com/products/raceanisodamine.html","C17H23NO4","free base","7β-Hydroxyhyoscyamine","CN1C2CC(O)C1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",{"v":0.63,"d":"0.630"},2,2,5]
["S5713","Pravastatin","e7","L3800-28","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","Marketed","HMG-CoA Reductase","Metabolism","Pravastatin(CS-514) is a lipoprotein-lowering drug via reversibly inhibiting hydroxymethylglutaryl-CoA (HMG-CoA) reductase and the synthesis of very-low-density lipoproteins.",424.53,"81093-37-0",{"v":85,"d":"85.00"},200.22,{"v":85,"d":"85.00"},200.22,"http://www.selleckchem.com/products/pravastatin.html","C23H36O7","Free Base","CS-514","CCC(C)C(=O)OC1CC(O)C=C2C=CC(C)C(CCC(O)CC(O)CC(O)=O)C12",2.156,3,3,11]
["S5714","lurasidone","f7","L3800-28","in 10mM DMSO","FDA,DMF,EMA,NDC","N/A","Marketed","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Lurasidone (SM-13496) is a second-generation antipsychotic agent that exhibits full antagonism at dopamine D2 and serotonin 5-HT2A receptors with binding affinities Ki = 1 nM and Ki = 0.5 nM, respectively. It also has high affinity for serotonin 5-HT7 receptors (Ki = 0.5 nM), partial agonist activity at 5-HT1A receptors (Ki = 6.4 nM) and lacks affinity for histamine H1 and muscarinic M1 receptors.",492.68,"367514-87-2",{"v":7,"d":"7.00"},14.21,"<1","N/A","http://selleckchem.com/products/lurasidone.html","C28H36N4O2S","free base","SM-13496","O=C1C2C3CCC(C3)C2C(=O)N1CC4CCCCC4CN5CCN(CC5)C6=NSC7=CC=CC=C67",4.896,3,0,5]
["S5717","Acetohexamide","a8","L3800-28","in 10mM DMSO","FDA,DMF,PMDA","Martindale:The Extra Pharmacopoeia,JP17,USP39-NF34","N/A","Others","Others","Acetohexamide is an intermediate-acting, first-generation oral sulfonylurea with hypoglycemic activity. It exerts the blood-glucose-lowering effects by stimulating the pancreatic beta cells to secrete insulin and by helping the body use insulin efficiently.",{"v":324.4,"d":"324.40"},"968-81-0",{"v":11,"d":"11.00"},33.91,"<1","N/A","http://selleckchem.com/products/acetohexamide.html","C15H20N2O4S","free base","N/A","CC(=O)C1=CC=C(C=C1)[S](=O)(=O)NC(=O)NC2CCCCC2",2.119,4,2,4]
["S5722","Oxantel Pamoate","e8","L3800-28","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","N/A","Parasite","Microbiology","Oxantel Pamoate is the pamoate salt form of oxantel, a tetrahydropyrimidine anthelmintic used against intesitnal worms, particularly in a veterinary setting.",604.65,"68813-55-8",{"v":100,"d":"100.00"},165.38,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/oxantel-pamoate.html","C36H32N2O7","pamoate salt","N/A","CN1CCCN=C1\\C=C\\C2=CC(=CC=C2)O.OC(=O)C3=C(O)C(=C4C=CC=CC4=C3)CC5=C6C=CC=CC6=CC(=C5O)C(O)=O",6.008,3,3,6]
["S5726","Triiodothyronine","h8","L3800-28","in 10mM DMSO","CFDA","N/A","N/A","THR","Metabolism","Triiodothyronine (T3, Liothyronine, 3,3',5-Triiodo-L-thyronine) is a thyroid hormone that affects various physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.This product is soluble but easy to precipitate after freezing in DMSO. NaOH is recommended as a stock solution.",650.97,"6893-02-3",{"v":100,"d":"100.00"},153.62,"<1","N/A","http://www.selleckchem.com/products/triiodothyronine.html","C15H12I3NO4","Free Base","T3, Liothyronine, 3,3',5-Triiodo-L-thyronine","NC(CC1=CC(=C(OC2=CC=C(O)C(=C2)I)C(=C1)I)I)C(O)=O",1.448,2,2,5]
["S5729","Fosfosal","c9","L3800-28","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Immunology & Inflammation related","Immunology & Inflammation","Fosfosal (2-phosphonoxy benzoic acid) is a non-acetylated salicylic acid derivative, with analgesic and anti-inflammatory activity, but without effects on PG biosynthesis in vitro.",{"v":218.1,"d":"218.10"},"6064-83-1",{"v":43,"d":"43.00"},197.16,{"v":-1,"d":"-1.00"},-4.59,"https://www.selleckchem.com/products/fosfosal.html","C7H7O6P","free base","2-phosphonoxy benzoic acid","OC(=O)C1=C(O[P](O)(O)=O)C=CC=C1",0.963,2,0,3]
["S5733","Stearic acid","f9","L3800-28","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","N/A","Others","Others","Stearic acid (Octadecanoic acid, Isostearic acid, Cetylacetic acid) is a natural saturated fatty acid found in animal and vegetable fats. It could be used as a food additive and used in soaps, cosmetics and detergents.",284.48,"57-11-4",{"v":57,"d":"57.00"},200.37,{"v":-1,"d":"-1.00"},-3.52,"https://www.selleckchem.com/products/stearic-acid.html","C18H36O2","free base","Octadecanoic acid, Isostearic acid, Cetylacetic acid","CCCCCCCCCCCCCCCCCC(O)=O",7.305,1,0,16]
["S5737","Diclofenac Epolamine","b10","L3800-28","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia","Phase 3","Immunology & Inflammation related","Immunology & Inflammation","Diclofenac Epolamine (DHEP, DIEP, diclofenac hydroxyethylpyrrolidine) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.",411.32,"119623-66-4",{"v":82,"d":"82.00"},199.36,{"v":82,"d":"82.00"},199.36,"http://www.selleckchem.com/products/diclofenac-epolamine.html","C20H24Cl2N2O3","Epolamine","DHEP, DIEP, diclofenac hydroxyethylpyrrolidine","OCCN1CCCC1.OC(=O)CC2=C(NC3=C(Cl)C=CC=C3Cl)C=CC=C2",{"v":1.58,"d":"1.580"},1,2,6]
["S5741","Quetiapine","e10","L3800-28","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,JP17,BP2017,IP2010","Marketed","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Quetiapine(ICI204636) is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.Quetiapine is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine is a dopamine receptor antagonist with a pIC50 of 6.33 for human D2 receptor. Quetiapine have moderate to high affinity for the human D2, HT1A, 5-HT2A, 5-HT2C receptor with pKis of 7.23, 5.74, 7.54, 5.55.",383.51,"111974-69-7",{"v":77,"d":"77.00"},200.78,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/quetiapine.html","C21H25N3O2S","Free Base","ICI204636","OCCOCCN1CCN(CC1)C2=NC3=CC=CC=C3SC4=C2C=CC=C4",2.656,2,1,6]
["S5742","Deferoxamine mesylate (Ba 33112)","f10","L3800-28","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","USP42-NF37,IP2010","N/A","Autophagy,Beta Amyloid,Ferroptosis,HIF","Autophagy","Deferoxamine mesylate (Ba 33112, Desferrioxamine B, DFOM, NSC 644468) is the mesylate salt of Deferoxamine, which forms iron complexes and is used as a chelating agent. Deferoxamine is a ferroptosis inhibitor that stabilizes HIF-1α expression and improves HIF-1α transactivity in hypoxic and hyperglycemic states in vitro. Deferoxamine decreases beta-amyloid (Aβ) deposition and induces autophagy.Please do not prepare stock solutions with normal saline or PBS, as precipitation may occur.",656.79,"138-14-7",{"v":100,"d":"100.00"},152.26,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/deferoxamine-mesylate.html","C26H52N6O11S","mesylate","Desferrioxamine B, DFOM, NSC 644468","CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN.C[S](O)(=O)=O",-1.304,5,3,23]
["S5749","Chlorpromazine","a11","L3800-28","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017,IP2010","N/A","5-HT Receptor,Dopamine Receptor,Potassium Channel,Sodium Channel","Neuronal Signaling","Chlorpromazine (CPZ) is a low-potency typical antipsychotic agent that is used to treat psychotic disorders such as schizophrenia. Chlorpromazine (CPZ) inhibits 5-HT(2A) receptor and dopamine D2 in vitro. Chlorpromazine (CPZ) also inhibits sodium channel and blocks HERG potassium channels with IC50 of 21.6 μM.",318.86,"50-53-3",{"v":64,"d":"64.00"},200.72,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/chlorpromazine.html","C17H19ClN2S","Free Base","CPZ","CN(C)CCCN1C2=C(SC3=C1C=C(Cl)C=C3)C=CC=C2",4.739,0,0,4]
["S5753","Setipiprant (ACT-129968)","d11","L3800-28","in 10mM DMSO","N/A","N/A","Phase 2","Prostaglandin Receptor","GPCR & G Protein","Setipiprant (ACT-129968, KYTH-105) is a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2) that that has been shown to have greater specificity for DP2 (CRTH2) than for DP1.",402.42,"866460-33-5",{"v":80,"d":"80.00"},{"v":198.8,"d":"198.80"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/act-129968-setipiprant.html","C24H19FN2O3","Free Base","KYTH-105","OC(=O)C[N]1C2=C(CN(CC2)C(=O)C3=C4C=CC=CC4=CC=C3)C5=C1C=CC(=C5)F",4.002,2,0,3]
["S5759","Methyl linoleate","h11","L3800-28","in 10mM DMSO","N/A","USP42-NF37;BP2019;EP9.2","N/A","Others","Others","Methyl linoleate (Linoleic acid methyl ester), found in cloves, is a fatty acid methyl ester of linoleic acid which is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes.",294.47,"112-63-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/methyl-linoleate.html","C19H34O2","Free Base","Linoleic acid methyl ester","CCCCC/C=C\\C\\C=C/CCCCCCCC(=O)OC",6.641,2,0,15]
["S5763","D-Mannose","c2","L3800-29","in 10mM DMSO","N/A","BP2015","N/A","Others","Others","D-mannose is a naturally occurring simple sugar that may help your body cleanse the urinary tract and maintain a healthy bladder lining.",180.16,"3458-28-4",{"v":36,"d":"36.00"},199.82,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/d-mannose.html","C6H12O6","Free Base","N/A","OCC1OC(O)C(O)C(O)C1O",-2.514,1,4,1]
["S5768","Fenoterol hydrobromide","g2","L3800-29","in 10mM DMSO","PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,BP2017","Phase 3","Adrenergic Receptor","Neuronal Signaling","Fenoterol hydrobromide (Phenoterol) is the the hydrobromide salt of fenoterol, a β2 adrenoreceptor agonist with bronchodilator activity.",384.26,"1944-12-3",{"v":77,"d":"77.00"},200.39,{"v":11,"d":"11.00"},28.63,"http://www.selleckchem.com/products/fenoterol-hydrobromide.html","C17H22BrNO4","hydrobromide","Phenoterol hydrobromide","Br.CC(CC1=CC=C(O)C=C1)NCC(O)C2=CC(=CC(=C2)O)O",2.904,0,5,6]
["S5776","Proflavine","b3","L3800-29","in 10mM DMSO","NDC","Martindale:The Extra Pharmacopoeia","Phase 2","Bacterial","Microbiology","Proflavine (3,6-Diaminoacridine) is a disinfectant bacteriostatic against many gram-positive bacteria. It is a topical antiseptic used mainly in wound dressings.",209.25,"92-62-6",{"v":23,"d":"23.00"},109.92,{"v":1,"d":"1.00"},4.78,"http://www.selleckchem.com/products/proflavine.html","C13H11N3","Free Base","3,6-Diaminoacridine","NC1=CC2=NC3=CC(=CC=C3C=C2C=C1)N",{"v":1.86,"d":"1.860"},1,2,0]
["S5780","Prazosin","e3","L3800-29","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017,IP2010","N/A","Adrenergic Receptor","Neuronal Signaling","Prazosin is an α1-blocker that acts as an inverse agonist at alpha-1 adrenergic receptors. It is used to treat hypertension.",{"v":383.4,"d":"383.40"},"19216-56-9",{"v":77,"d":"77.00"},200.83,{"v":1,"d":"1.00"},2.61,"http://www.selleckchem.com/products/prazosin.html","C19H21N5O4","Free Base","N/A","COC1=CC2=NC(=NC(=C2C=C1OC)N)N3CCN(CC3)C(=O)C4=CC=CO4",2.107,6,1,4]
["S5781","Raloxifene","f3","L3800-29","in 10mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Raloxifene (Keoxifene, Pharoxifene, LY-139481, LY-156758, CCRIS-7129) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women.",473.58,"84449-90-1",{"v":95,"d":"95.00"},{"v":200.6,"d":"200.60"},{"v":1,"d":"1.00"},2.11,"http://www.selleckchem.com/products/raloxifene.html","C28H27NO4S","Free Base","Keoxifene, Pharoxifene, LY-139481, LY-156758, CCRIS-7129","OC1=CC=C(C=C1)C2=C(C(=O)C3=CC=C(OCCN4CCCCC4)C=C3)C5=C(S2)C=C(O)C=C5",6.461,2,2,7]
["S5784","Vancomycin","a4","L3800-29","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8,KP Ⅹ,JP17,BP2017,IP2010","Registered","Antibiotics,Antibiotics for Plant Cell Culture,Bacterial","Microbiology","Vancomycin is an antibiotic used to treat serious bacterial infections. It works by stopping the growth of bacteria.",1449.25,"1404-90-6",{"v":29,"d":"29.00"},20.01,{"v":1,"d":"1.00"},0.69,"http://www.selleckchem.com/products/vancomycin.html","C66H75Cl2N9O24","Free Base","N/A","CNC(CC(C)C)C(=O)NC1C(O)C2=CC(=C(OC3=C(OC4OC(CO)C(O)C(O)C4OC5CC(C)(N)C(O)C(C)O5)C6=CC(=C3)C(NC(=O)C(CC(N)=O)NC1=O)C(=O)NC7C(=O)NC(C(O)C8=CC(=C(O6)C=C8)Cl)C(=O)NC(C(O)=O)C9=C(C(=CC(=C9)O)O)C%10=C(O)C=CC7=C%10)C=C2)Cl",-2.926,14,18,13]
["S5795","Rasagiline","d4","L3800-29","in 10mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","MAO","Metabolism","Rasagiline (TVP-1012) is a novel selective and irreversible MAO-B propargylamine inhibitor with in vitro IC50s of 4.43 nM and 412 nM for MAO-B and MAO-A, respectively.",171.24,"136236-51-6",{"v":34,"d":"34.00"},198.55,{"v":4,"d":"4.00"},23.36,"http://www.selleckchem.com/products/rasagiline.html","C12H13N","Free Base","TVP-1012","C#CCNC1CCC2=C1C=CC=C2",3.119,0,1,2]
["S5805","Allopregnanolone","h4","L3800-29","in 10mM DMSO","FDA","N/A","N/A","GABA Receptor","Neuronal Signaling","Allopregnanolone, a neurosteroid synthesized from progesterone in brain, acts as a highly potent positive allosteric modulator of the GABAA receptor.",318.49,"516-54-1",{"v":64,"d":"64.00"},200.95,"<1","N/A","http://www.selleckchem.com/products/allopregnanolone.html","C21H34O2","Free Base","N/A","CC(=O)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C",3.874,1,1,1]
["S5812","Choline Fenofibrate","c5","L3800-29","in 10mM DMSO","FDA,DMF","N/A","Marketed","PPAR","Metabolism","Choline fenofibrate(ABT-335) is a newly developed choline salt of fenofibric acid, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity that acts as an PPARα agonist.",421.91,"856676-23-8",{"v":5,"d":"5.00"},11.85,{"v":9,"d":"9.00"},21.33,"http://www.selleckchem.com/products/choline-fenofibrate.html","C22H28ClNO5","Free Base","ABT-335","CC(C)(OC1=CC=C(C=C1)C(=O)C2=CC=C(Cl)C=C2)C([O-])=O.C[N+](C)(C)CCO",1.111,2,1,7]
["S5821","Linoleic acid","g5","L3800-29","in 10mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","N/A","Others","Others","Linoleic acid (9,12-octadecadienoic acid) is an essential fatty acid used in the biosynthesis of arachidonic acid and found in the lipids of cell membranes.,",280.45,"60-33-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/linoleic-acid.html","C18H32O2","Free Base","9,12-octadecadienoic acid","CCCCC/C=C\\C\\C=C/CCCCCCCC(O)=O",6.416,1,0,14]
["S5827","Citronellyl acetate","a6","L3800-29","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Others","Others","Citronellyl acetate (Citronellol acetate) is a natural flavouring ingredient.",{"v":198.3,"d":"198.30"},"150-84-5","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/citronellyl-acetate.html","C12H22O2","Free Base","Citronellol acetate","CC(CCOC(C)=O)CCC=C(C)C",3.428,2,0,7]
["S5840","Palifosfamide","d6","L3800-29","in 10mM DMSO","N/A","N/A","Phase 3","DNA alkylator","DNA Damage/DNA Repair","Palifosfamide (ZIO-201, Isophosphamide mustard) is a novel DNA alkylator and the active metabolite of ifosfamide with potential antineoplastic activity.",221.02,"31645-39-3",{"v":44,"d":"44.00"},199.08,{"v":13,"d":"13.00"},58.82,"http://www.selleckchem.com/products/palifosfamide.html","C4H11Cl2N2O2P","Free Base","ZIO-201, Isophosphamide mustard","O[P](=O)(NCCCl)NCCCl",0.018,1,2,6]
["S5842","Cabergoline","e6","L3800-29","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","Marketed","Dopamine Receptor","Neuronal Signaling","Cabergoline (FCE-21336), an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor.",{"v":451.6,"d":"451.60"},"81409-90-7",{"v":90,"d":"90.00"},199.29,{"v":1,"d":"1.00"},2.21,"http://www.selleckchem.com/products/cabergoline.html","C26H37N5O2","Free Base","FCE-21336","CCNC(=O)N(CCCN(C)C)C(=O)C1CC2C(CC3=C[NH]C4=C3C2=CC=C4)N(CC=C)C1",3.036,2,2,8]
["S5847","Ethacrynate Sodium","h6","L3800-29","in 10mM DMSO","FDA,DMF,NDC","USP39-NF34","N/A","Proton Pump","Transmembrane Transporters","Ethacrynate Sodium (ethacrynic acid sodium) is the sodium salt form of ethacrynic acid, which inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules.",325.12,"6500-81-8",{"v":65,"d":"65.00"},199.93,{"v":65,"d":"65.00"},199.93,"http://www.selleck.cn/products/ethacrynate-sodium.html","C13H11Cl2NaO4","Sodium","ethacrynic acid sodium","[Na+].CCC(=C)C(=O)C1=C(Cl)C(=C(OCC([O-])=O)C=C1)Cl",2.489,2,0,6]
["S5858","Vilazodone","d7","L3800-29","in 10mM DMSO","FDA,DMF,NDC","N/A","Marketed","5-HT Receptor,Serotonin Transporter","Neuronal Signaling","Vilazodone (EMD-68843, SB-659746A) is a novel antidepressant having a selective serotonin (5-HT) reuptake inhibitory and 5-HT1A receptor partial agonist activity. The affinity of vilazodone is much higher in the 5-HT reuptake site (Ki=0.1 nM) than in norepinephrine (Ki=56 nM) and dopamine (Ki=37 nM) sites.",441.52,"163521-12-8",{"v":88,"d":"88.00"},199.31,{"v":1,"d":"1.00"},2.26,"https://www.selleckchem.com/products/vilazodone.html","C26H27N5O2","Free Base","EMD-68843, SB-659746A","NC(=O)C1=CC2=C(O1)C=CC(=C2)N3CCN(CCCCC4=C[NH]C5=C4C=C(C=C5)C#N)CC3",4.536,2,2,7]
["S5862","Metoclopramide","g7","L3800-29","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.4,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","Marketed","Dopamine Receptor","Neuronal Signaling","Metoclopramide is a dopamine antagonist used for the treatment of nausea and vomiting.",{"v":299.8,"d":"299.80"},"364-62-5",{"v":60,"d":"60.00"},200.13,{"v":1,"d":"1.00"},3.34,"http://www.selleckchem.com/products/metoclopramide.html","C14H22ClN3O2","Free Base","N/A","CCN(CC)CCNC(=O)C1=C(OC)C=C(N)C(=C1)Cl",1.775,2,2,7]
["S5869","Cortisone","b8","L3800-29","in 10mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP35-NF30,BP2010,JP15","N/A","Immunology & Inflammation related","Immunology & Inflammation","Cortisone is a pregnane steroid hormone and one of main substance released by the body as a reaction to stress. It suppresses the immune system, thus reducing inflammation and attendant pain and swelling at the site of the injury.",360.44,"53-06-5",{"v":72,"d":"72.00"},199.76,{"v":1,"d":"1.00"},2.77,"https://www.selleckchem.com/products/cortisone.html","C21H28O5","Free Base","N/A","CC12CCC(=O)C=C1CCC3C4CCC(O)(C(=O)CO)C4(C)CC(=O)C23",{"v":1.24,"d":"1.240"},3,1,2]
["S5874","D-Carnitine hydrochloride","f8","L3800-29","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia","Marketed","Mitochondrial Metabolism","Metabolism","D-Carnitine hydrochloride ((S)-Carnitine hydrochloride, (+)-Carnitine hydrochloride) is biosynthesized from lysine. It might be associated with the energy production from branched chain amino acids.",197.66,"10017-44-4",{"v":40,"d":"40.00"},202.37,{"v":40,"d":"40.00"},202.37,"https://www.selleckchem.com/products/d-carnitine-hydrochloride.html","C7H16ClNO3","hydrochloride","(S)-Carnitine hydrochloride, (+)-Carnitine hydrochloride","[Cl-].C[N+](C)(C)CC(O)CC(O)=O",{"v":-4.49,"d":"-4.490"},1,1,4]
["S5900","Edrophonium chloride","a9","L3800-29","in 10mM DMSO","FDA,DMF,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017","N/A","AChR","Metabolism","Edrophonium chloride is the chloride salt of edrophonium, which is a rapid-onset, short-acting, readily reversible inhibitor of acetylcholinesterase.",201.69,"116-38-1",{"v":40,"d":"40.00"},198.32,{"v":40,"d":"40.00"},198.32,"http://www.selleckchem.com/products/edrophonium-chloride.html","C10H16ClNO","chloride","N/A","[Cl-].CC[N+](C)(C)C1=CC=CC(=C1)O",-2.026,0,1,2]
["S5909","Anagliptin","d9","L3800-29","in 10mM DMSO","PMDA","N/A","Marketed","DPP","Proteases","Anagliptin is an orally active and highly selective dipeptidyl peptidase-4 (DPP-4) inhibitor and exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation.",383.45,"739366-20-2",{"v":77,"d":"77.00"},200.81,{"v":20,"d":"20.00"},52.16,"http://www.selleckchem.com/products/anagliptin.html","C19H25N7O2","Free Base","N/A","CC1=N[N]2C=C(C=NC2=C1)C(=O)NCC(C)(C)NCC(=O)N3CCCC3C#N",-0.629,4,2,6]
["S5911","Bictegravir","e9","L3800-29","in 10mM DMSO","FDA,EMA,NDC","N/A","N/A","COVID-19,Integrase","Microbiology","Bictegravir (GS-9883) is a novel, potent, once-daily, unboosted inhibitor of HIV-1 integrase.",449.38,"1611493-60-7",{"v":90,"d":"90.00"},200.28,"<1","N/A","http://www.selleckchem.com/products/bictegravir.html","C21H18F3N3O5","Free Base","GS-9883","OC1=C2N(CC3OC4CCC(C4)N3C2=O)C=C(C(=O)NCC5=C(F)C=C(F)C=C5F)C1=O",0.646,4,2,3]
["S5923","Celiprolol hydrochloride","h9","L3800-29","in 10mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017","Preregistration","Adrenergic Receptor","Neuronal Signaling","Celiprolol is a β1-adrenoceptor antagonist with partial β2 agonist activity.",415.95,"57470-78-7",{"v":83,"d":"83.00"},199.54,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/celiprolol-hydrochloride.html","C20H34ClN3O4","hydrochloride","N/A","Cl.CCN(CC)C(=O)NC1=CC(=C(OCC(O)CNC(C)(C)C)C=C1)C(C)=O",1.978,3,3,10]
["S5927","Proguanil","d10","L3800-29","in 10mM DMSO","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,Ph.Int_6th,BP2017,IP2010","Marketed","Anti-infection,DHFR","Microbiology","Proguanil (chlorguanide, chloroguanide) is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.",253.73,"500-92-5",{"v":51,"d":"51.00"},{"v":201,"d":"201.00"},{"v":1,"d":"1.00"},3.94,"http://www.selleckchem.com/products/proguanil.html","C11H16ClN5","Free Base","chlorguanide, chloroguanide","CC(C)NC(=N)NC(=N)NC1=CC=C(Cl)C=C1",2.226,0,3,6]
["S5938","Benazepril","g10","L3800-29","in 10mM DMSO","FDA,CFDA,DMF,NDC,PMDA,HMA","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,BP2017","Marketed","RAAS","Endocrinology & Hormones","Benazepril is used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. Benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor.",424.49,"86541-75-5",{"v":85,"d":"85.00"},200.24,"<1","N/A","http://www.selleck.cn/products/benazepril.html","C24H28N2O5","Free Base","N/A","CCOC(=O)C(CCC1=CC=CC=C1)NC2CCC3=C(C=CC=C3)N(CC(O)=O)C2=O",0.621,4,1,10]
["S5943","Bromhexine","b11","L3800-29","in 10mM DMSO","CFDA,PMDA,HMA","Martindale the Extra Pharmacopoei,EP8.8,KP Ⅹ,JP17,BP2017,IP2010","N/A","Others","Others","Bromhexine is an expectorant/mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus",376.13,"3572-43-8",{"v":75,"d":"75.00"},{"v":199.4,"d":"199.40"},"<1","N/A","http://www.selleck.cn/products/bromhexine.html","C14H20Br2N2","Free Base","N/A","CN(CC1=CC(=CC(=C1N)Br)Br)C2CCCCC2",4.512,0,1,3]
["S5951","Cefoxitin","f11","L3800-29","in 10mM DMSO","FDA,CFDA,DMF,NDC,HMA","Martindale the Extra Pharmacopoei,EP8.8,USP42-NF37,KP Ⅹ,BP2017","N/A","Antibiotics,Bacterial","Microbiology","Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.",427.45,"35607-66-0",{"v":85,"d":"85.00"},198.85,"<1","N/A","http://www.selleck.cn/products/cefoxitin.html","C16H17N3O7S2","Free Base","N/A","COC1(NC(=O)CC2=CC=CS2)C3SCC(=C(N3C1=O)C(O)=O)COC(N)=O",0.323,6,2,8]
["S6003","Ataluren (PTC124)","a2","L3800-30","in 10mM DMSO","EMA","N/A","Marketed","CFTR","Transmembrane Transporters","Ataluren (PTC124) selectively induces ribosomal read-through of premature but not normal termination codons, with EC50 of 0.1 μM in HEK293 cells, may provide treatment for genetic disorders caused by nonsense mutations (e.g. CF caused by CFTR nonsense mutation). Phase 3.",284.24,"775304-57-9",{"v":57,"d":"57.00"},200.53,"<1","N/A","http://selleckchem.com/products/PTC124.html","C15H9FN2O3","free base","N/A","OC(=O)C1=CC=CC(=C1)C2=NOC(=N2)C3=CC=CC=C3F",{"v":2.98,"d":"2.980"},4,0,3]
["S6007","Bisphenol A","d2","L3800-30","in 10mM DMSO","NDC","N/A","N/A","Others","Others","Bisphenol A is a starting material for the synthesis of plastics, primarily certain polycarbonates and epoxy resins, as well as some polysulfones and certain niche materials. It exhibits estrogen-mimicking, hormone-like properties.",228.29,"80-05-7",{"v":45,"d":"45.00"},197.12,"N/A","N/A","http://www.selleck.cn/products/bisphenol-a.html","C15H16O2","free base","N/A","CC(C)(C1=CC=C(O)C=C1)C2=CC=C(O)C=C2",3.778,0,2,2]
["S6010","Sodium L-lactate","e2","L3800-30","in 10mM DMSO","HMA","JP17","N/A","Others","Others","Sodium L-lactate is used as a food additive, preservative, acidity regulator and bulking agent.",113.07,"867-56-1",{"v":22,"d":"22.00"},196.32,"N/A","N/A","http://www.selleck.cn/products/sodium-l-lactate.html","C3H5NaO3","free base","N/A","[Na+].CC(O)C([O-])=O",-1.867,0,1,1]
["S6015","Benzylcetyldimethylammonium chloride hydrate","h2","L3800-30","in 10mM DMSO","FDA","N/A","Marketed","Others","Others","Benzylcetyldimethylammonium chloride hydrate is a chemical.",396.09,"122-18-9",{"v":82,"d":"82.00"},207.02,"N/A","N/A","http://www.selleck.cn/products/benzylcetyldimethylammonium-chloride-hydrate.html","C25H46ClN","hydrate","N/A","[Cl-].CCCCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1",4.678,0,0,17]
["S6049","(+)-(S)-Carvone","d3","L3800-30","in 10mM DMSO","N/A","BP2017","N/A","Others","Others","(+)-(S)-Carvone, a monoterpene found mainly in caraway and dill seed oils, is used in cosmetic, food and pharmaceutical preparations.",150.22,"2244-16-8","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleck.cn/products/s-carvone.html","C10H14O","free base","N/A","CC(=C)C1CC=C(C)C(=O)C1",2.501,1,0,1]
["S6053","Phenylglyoxylic acid","f3","L3800-30","in 10mM DMSO","N/A","USP42-NF37","N/A","Others","Others","Phenylglyoxylic acid (Benzoyl formate, Phenylglyoxalic acid, Phenylglyoxylate) is a key building block in the field of chemical synthesis and is widely used to synthesize pharmaceutical intermediates or food additives.",150.13,"611-73-4",{"v":30,"d":"30.00"},199.83,"N/A","N/A","http://www.selleck.cn/products/phenylglyoxylic-acid.html","C8H6O3","free base","Benzoyl formate, Phenylglyoxalic acid, Phenylglyoxylate","OC(=O)C(=O)C1=CC=CC=C1",1.345,2,0,2]
["S6065","Congo Red","a4","L3800-30","in 10mM DMSO","N/A","Martindale the Extra Pharmacopoei, EP10.2, USP43-NF38 , IP2010","N/A","Dyes","Others","Congo Red (Direct Red 28) is an indicator dye that is blue-violet at pH 3.0 and red at pH 5.0. It is an acid dye used in testing for hydrochloric acid in gastric contents but has carcinogenic properties.",696.66,"573-58-0",{"v":139,"d":"139.00"},199.52,"N/A","N/A","http://www.selleck.cn/products/congo-red.html","C32H22N6Na2O6S2","free base","Direct Red 28","[Na+].[Na+].NC1=C2C=CC=CC2=C(C=C1N=NC3=CC=C(C=C3)C4=CC=C(C=C4)N=NC5=CC(=C6C=CC=CC6=C5N)[S]([O-])(=O)=O)[S]([O-])(=O)=O",2.586,4,2,7]
["S6079","2-Methylhexanoic acid","e4","L3800-30","in 10mM DMSO","DMF","N/A","N/A","Others","Others","2-Methylhexanoic acid is a flavouring ingredient.",130.18,"4536-23-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleck.cn/products/2-methylhexanoic-acid.html","C7H14O2","free base","N/A","CCCCC(C)C(O)=O",2.293,1,0,4]
["S6113","Tridecanoic acid","h4","L3800-30","in 10mM DMSO","N/A","N/A","Phase 2","Others","Others","Tridecanoic acid (Tridecylic acid) is a 13-carbon saturated fatty acid found in many foods, some of which are nutmeg, muskmelon, black elderberry, and coconut.",214.34,"638-53-9",{"v":42,"d":"42.00"},195.95,"N/A","N/A","http://www.selleck.cn/products/tridecanoic-acid.html","C13H26O2","free base","Tridecylic acid","CCCCCCCCCCCCC(O)=O",5.024,1,0,11]
["S6115","Pyridoxal 5′-phosphate hydrate","a5","L3800-30","in 10mM DMSO","PMDA","USP43-NF38","N/A","DNA/RNA Synthesis","DNA Damage/DNA Repair","Pyridoxal 5′-phosphate (pyridoxal phosphate, Vitamin B6 phosphate, PAL-P, PLP), a vitamin B6 phosphate, is a coenzyme in a variety of enzymatic reactions. Pyridoxal 5′-phosphate at concentrations < 0.5 mM inhibits of polymerization deoxynucleoside triphosphate catalysed by variety of DNA polymerases isolated from type C RNA tumor viruses. The combination of Pyridoxal 5′-phosphate and NEIL2 will make NEIL2 completely lose its ability to bind damaged DNA.",247.14,"853645-22-4",{"v":10,"d":"10.00"},40.46,"N/A","N/A","http://www.selleck.cn/products/pyridoxal-5-phosphate-hydrate.html","C8H10NO6P.xH2O","hydrate","pyridoxal phosphate, Vitamin B6 phosphate, PAL-P, PLP","CC1=NC=C(CO[P](O)(O)=O)C(=C1O)C=O",0.537,3,1,4]
["S6136","(±)-α-Bisabolol","d5","L3800-30","in 10mM DMSO","N/A","EP10.4","N/A","Anti-infection,Immunology & Inflammation related","Immunology & Inflammation","α-bisabolol is a small, plant-derived, oily sesquiterpene alcohol with some anti-inflammatory and even anti-microbial properties.",222.37,"515-69-5","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleck.cn/products/bisabolol.html","C15H26O","free base","N/A","CC(C)=CCCC(C)(O)C1CCC(=CC1)C",4.309,0,0,4]
["S6173","Amylmetacresol","g5","L3800-30","in 10mM DMSO","N/A","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Anti-infection","Microbiology","Amylmetacresol is an antiseptic used to treat infections of the mouth and throat.",178.27,"1300-94-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleck.cn/products/amylmetacresol.html","C12H18O","free base","N/A","CCCCCC1=C(O)C=C(C)C=C1",4.385,0,1,4]
["S6197","Dimethylamine hydrochloride","c6","L3800-30","in 10mM DMSO","N/A","BP2017;IP2010","N/A","Others","Others","Dimethylamine is a precursor to several industrially significant compounds.",81.54,"506-59-2",16.31,{"v":200,"d":"200.00"},"N/A","N/A","http://www.selleck.cn/products/dimethylamine-hydrochloride.html","C2H8ClN","hydrochloride","N/A","Cl.CNC",0.166,0,1,0]
["S6210","Ethanolamine hydrochloride","f6","L3800-30","in 10mM DMSO","FDA,DMF,NDC","EP9.2,BP2017","N/A","Others","Others","Ethanolamine (2-Aminoethanol) is a viscous, hygroscopic amino alcohol with an ammoniacal odor. It is widely distributed in biological tissue and is a component of lecithin.",97.54,"2002-24-6",19.51,{"v":200,"d":"200.00"},"N/A","N/A","http://www.selleck.cn/products/ethanolamine-hydrochloride.html","C2H8ClNO","hydrochloride","2-Aminoethanol hydrochloride","Cl.NCCO",-0.805,0,2,1]
["S6218","Sodium lauryl sulfate","a7","L3800-30","in 10mM DMSO","DMF,NDC","KP Ⅹ,JP17,BP2017,USP39-NF34","N/A","Others","Others","Sodium lauryl sulfate is an anionic detergent and surfactant found in many personal care products.",288.38,"151-21-3",57.68,{"v":200,"d":"200.00"},"N/A","N/A","http://www.selleck.cn/products/sodium-lauryl-sulfate.html","C12H25NaO4S","free base","N/A","[Na+].CCCCCCCCCCCCO[S]([O-])(=O)=O",2.165,1,0,12]
["S6232","Methylamine hydrochloride","e7","L3800-30","in 10mM DMSO","N/A","EP10.4, USP43-NF38","N/A","Others","Others","Methylamine is used as a building block for the synthesis of many other commercially available compounds.",67.52,"593-51-1",{"v":13.5,"d":"13.50"},{"v":200,"d":"200.00"},"N/A","N/A","http://www.selleck.cn/products/methylamine-hydrochloride.html","CH6ClN","hydrochloride","N/A","Cl.CN",-0.266,0,1,0]
["S6235","Sodium dehydroacetate","h7","L3800-30","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP39-NF34","N/A","Bacterial","Microbiology","Sodium dehydroacetate is the sodium salt of dehydroacetic acid, a fungicide and bactericide that is commonly used as a food preservative. Sodium dehydroacetate is a preservative that is used in the formulation of cosmetics and personal care products in order to extend the shelf-life by preventing microbial contamination.",190.13,"4418-26-2",38.03,{"v":200,"d":"200.00"},"N/A","N/A","http://www.selleck.cn/products/sodium-dehydroacetate.html","C8H7NaO4","free base","N/A","[Na+].CC(=O)C1=C([O-])C=C(C)OC1=O",-0.714,3,0,1]
["S6243","Ethyl pyruvate","a8","L3800-30","in 10mM DMSO","N/A","N/A","Phase 4","Anti-infection,Immunology & Inflammation related","Immunology & Inflammation","Ethyl pyruvate (CTI-01) is a simple aliphatic ester of pyruvic acid and has been shown to have robust neuroprotective effects via its anti-inflammatory, anti-oxidative, and anti-apoptotic functions.",116.12,"617-35-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleck.cn/products/ethyl-pyruvate.html","C5H8O3","free base","CTI-01","CCOC(=O)C(C)=O",0.246,3,0,3]
["S6251","Terephthalic acid","d8","L3800-30","in 10mM DMSO","DMF","N/A","N/A","Others","Others","Terephthalic acid (para-Phthalic acid, 1,4-Benzenedioic acid), a raw material for polyethylene terephthalate (PET) production, is one of the most important chemicals in petrochemical industry.",166.13,"100-21-0",33.23,{"v":200,"d":"200.00"},"N/A","N/A","http://www.selleck.cn/products/terephthalic-acid.html","C8H6O4","free base","para-Phthalic acid; 1,4-Benzenedioic acid","OC(=O)C1=CC=C(C=C1)C(O)=O",1.089,2,0,2]
["S6262","Ammonium formate","g8","L3800-30","in 10mM DMSO","N/A","USP42-NF37;BP2019;EP9.2","N/A","Others","Others","Ammonium Formate is the ammonium salt of formic acid. It is widely used in various organic reactions.",63.06,"540-69-2",12.61,{"v":200,"d":"200.00"},"N/A","N/A","http://www.selleck.cn/products/ammonium-formate.html","CH5NO2","free base","N/A","NOC=O",-0.942,1,1,1]
["S6275","(−)-β-Pinene","c9","L3800-30","in 10mM DMSO","CFDA","BP2013","N/A","Others","Others","(−)-β-Pinene (Nopinene) is a natural organic compound in various plants. It is lethal to S. littoralis third instar larvae (LD50 = 65 μg/larva), inhibits infectious bronchitis virus (IBV) replication (IC50 = 1.32 mM) and exhibits a cytotoxic concentration (CC50) value of greater than 10 mM in Vero cells.",136.23,"18172-67-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleck.cn/products/pinene.html","C10H16","free base","Nopinene","CC1(C)C2CCC(=C)C1C2",2.926,0,0,0]
["S6288","Chlorhexidine diacetate","f9","L3800-30","in 10mM DMSO","DMF,NDC,HMA","EP9.4,Ph.Int_6th,BP2015,IP2010","N/A","Anti-infection","Microbiology","Chlorhexidine diacetate (Hibitane diacetate) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.",625.55,"56-95-1",125.11,{"v":200,"d":"200.00"},"N/A","N/A","http://www.selleck.cn/products/chlorhexidine-diacetate.html","C26H38Cl2N10O4","diacetate","Hibitane diacetate","CC(O)=O.CC(O)=O.ClC1=CC=C(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC2=CC=C(Cl)C=C2)C=C1",3.964,2,6,17]
["S6324","5-Methoxytryptamine","a10","L3800-30","in 10mM DMSO","NDC","N/A","N/A","5-HT Receptor","Neuronal Signaling","5-Methoxytryptamine (Mexamine, Methoxytryptamine) is a tryptamine derivative that acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors.",190.24,"608-07-1",38.05,{"v":200,"d":"200.00"},"N/A","N/A","http://www.selleck.cn/products/5-methoxytryptamine.html","C11H14N2O","free base","Mexamine, Methoxytryptamine","COC1=CC2=C([NH]C=C2CCN)C=C1",1.534,1,2,3]
["S6346","L-(+)-Arabinose","e10","L3800-30","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Others","Others","L-(+)-Arabinose (DL-Arabinose, Pectinose) is used as a substrate to identify, differentiate and characterize pentose sugar isomerase(s).",150.13,"5328-37-0",30.03,{"v":200,"d":"200.00"},"N/A","N/A","https://www.selleckchem.com/products/l--arabinose.html","C5H10O5","free base","DL-Arabinose, Pectinose","OCC(O)C(O)C(O)C=O",{"v":-2.28,"d":"-2.280"},1,4,4]
["S6403","Chloramine-T","h10","L3800-30","in 10mM DMSO","N/A","EP8.8;BP2019","Marketed","Others","Others","Chloramine-T is a N-chlorinated and N-deprotonated sulfonamide used as a biocide and a mild disinfectant.",227.64,"127-65-1",{"v":46,"d":"46.00"},202.07,{"v":46,"d":"46.00"},202.07,"http://www.selleck.cn/products/chloramine-t.html","C7H7ClNNaO2S","Free Base","N/A","CC1=CC=C(C=C1)[S](=O)(=O)N([Na])Cl",1.714,2,0,2]
["S6404","Salicylamide","a11","L3800-30","in 10mM DMSO","NDC","Martindale the Extra Pharmacopoei,USP42-NF37","N/A","Immunology & Inflammation related","Immunology & Inflammation","Salicylamide (o-hydroxybenzamide) is a non-prescription drug with analgesic and antipyretic properties.",137.14,"65-45-2",{"v":27,"d":"27.00"},196.88,"˂1","N/A","http://www.selleck.cn/products/salicylamide.html","C7H7NO2","Free Base","o-hydroxybenzamide","NC(=O)C1=C(O)C=CC=C1",{"v":0.59,"d":"0.590"},1,2,1]
["S6407","Tulobuterol hydrochloride","c11","L3800-30","in 10mM DMSO","CFDA,PMDA","Martindale the Extra Pharmacopoei,KP Ⅹ,JP17","Marketed","Androgen Receptor","Neuronal Signaling","Tulobuterol is a long-acting β2-adrenergic receptor agonist that has bronchodilatory, anti-inflammatory, and antiviral activities.",264.19,"56776-01-3",{"v":53,"d":"53.00"},200.61,{"v":53,"d":"53.00"},200.61,"http://www.selleck.cn/products/tulobuterol-hydrochloride.html","C12H19Cl2NO","hydrochloride","N/A","Cl.CC(C)(C)NCC(O)C1=C(Cl)C=CC=C1",2.834,0,2,4]
["S6410","Clemizole","f11","L3800-30","in 10mM DMSO","N/A","Martindale the Extra Pharmacopoei","Phase 2","Dopamine Receptor,TRP Channel","Neuronal Signaling","Clemizole, a first-generation histamine receptor (H1) antagonist, is a potent inhibitor of behavioural and electrographic seizure activity. It has a potential therapeutic effect on hepatitis C infection and also potently inhibits TRPC5 ion channels.",325.84,"442-52-4",{"v":65,"d":"65.00"},199.48,{"v":-1,"d":"-1.00"},"N/A","http://www.selleck.cn/products/clemizole.html","C19H20ClN3","Free Base","N/A","ClC1=CC=C(C[N]2C(=NC3=C2C=CC=C3)CN4CCCC4)C=C1",4.527,1,0,4]
["S6415","Azeliragon (TTP488)","b2","L3800-31","in 10mM DMSO","N/A","N/A","Phase 3","Others","Others","Azeliragon (TTP488, PF-04494700) is an orally bioavailable small molecule that inhibits the receptor for advanced glycation endproducts (RAGE), which is an immunoglobulin-like cell surface receptor overexpressed in brain tissues of patients with AD.",532.12,"603148-36-3",{"v":100,"d":"100.00"},187.93,"<1","N/A","http://www.selleck.cn/products/azeliragon.html","C32H38ClN3O2","Free Base","PF-04494700","CCCCC1=NC(=C[N]1C2=CC=C(OC3=CC=C(Cl)C=C3)C=C2)C4=CC=C(OCCCN(CC)CC)C=C4",8.393,3,0,14]
["S6432","Cevimeline HCl hemihydrate","e2","L3800-31","in 10mM DMSO","FAD,DMF,NDC,PMDA","Martindale the Extra Pharmacopoei","Marketed","AChR","Metabolism","Cevimeline HCl hemihydrate(AF 102B, SNI 2011, SNK 508) is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3.",244.78,"153504-70-2",{"v":40,"d":"40.00"},169.66,{"v":40,"d":"40.00"},169.66,"https://www.selleckchem.com/products/cevimeline.html","C10H18ClNOS.1/2H2O","HCl hemihydrate","AF 102B, SNI 2011, SNK 508","Cl.CC1OC2(CS1)CN3CCC2CC3",2.151,1,0,0]
["S6440","Halazone","a3","L3800-31","in 10mM DMSO","N/A","Martindale the Extra Pharmacopoei,USP42-NF37","N/A","Others","Others","Halazone (Pantocide, p-sulfondichloramidobenzoic acid) is widely used to disinfect drinking water.",270.09,"80-13-7",{"v":54,"d":"54.00"},199.93,"<1","N/A","http://www.selleck.cn/products/halazone.html","C7H5Cl2NO4S","Free Base","Pantocide, p-sulfondichloramidobenzoic acid","OC(=O)C1=CC=C(C=C1)[S](=O)(=O)N(Cl)Cl",1.343,3,0,3]
["S6443","Chromium picolinate","d3","L3800-31","in 10mM DMSO","DMF ,NDC","USP42-NF37","N/A","IGF-1R","Protein Tyrosine Kinase","Chromium picolinate is a coordination complex consisting of chromium(III) and picolinic acid. It is used as a nutritional supplement for optimal insulin function in patients with Type 2 diabetes or promotion of weight loss.",{"v":418.3,"d":"418.30"},"14639-25-9",{"v":5,"d":"5.00"},11.95,"<1","N/A","http://www.selleck.cn/products/chromium-picolinate.html","C18H12CrN3O6","Free Base","N/A","[Cr+3]|1|2|3(|[O-]C(=O)C4=N|1C=CC=C4)(|[O-]C(=O)C5=N|2C=CC=C5)|[O-]C(=O)C6=N|3C=CC=C6",-1.647,0,0,0]
["S6448","Ibuprofen piconol","g3","L3800-31","in 10mM DMSO","PMDA","JP17","N/A","Immunology & Inflammation related","Immunology & Inflammation","Ibuprofen piconol (U75630) is a non-steroidal, anti-inflammatory (NSAID) drug for the topical relief of primary thermal burns and sunburns.",297.39,"64622-45-3","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleck.cn/products/ibuprofen-piconol.html","C19H23NO2","Free Base","U75630","CC(C)CC1=CC=C(C=C1)C(C)C(=O)OCC2=NC=CC=C2",4.481,3,0,7]
["S6450","Apronal","h3","L3800-31","in 10mM DMSO","marketed in Japan","N/A","N/A","Others","Others","Apronal (Apronalide, Allylisopropylacetylurea, Allylisopropylacetylcarbamide) is a hypnotic/sedative drug.",184.24,"528-92-7",{"v":37,"d":"37.00"},200.83,"<1","N/A","http://www.selleck.cn/products/apronal.html","C9H16N2O2","Free Base","Apronalide, Allylisopropylacetylurea, Allylisopropylacetylcarbamide","CC(C)C(CC=C)C(=O)NC(N)=O",1.306,2,2,4]
["S6454","Docosahexaenoic Acid","c4","L3800-31","in 10mM DMSO","NDC","Martindale the Extra Pharmacopoei,USP32-NF27","Phase 3","Others","Others","Docosahexaenoic Acid (DHA, Cervonic acid, Doconexent) is essential for the growth and functional development of the brain in infants. DHA is also required for maintenance of normal brain function in adults.",328.49,"6217-54-5",{"v":66,"d":"66.00"},200.92,{"v":8,"d":"8.00"},24.35,"http://www.selleck.cn/products/docosahexaenoic-acid.html","C22H32O2","Free Base","DHA, Cervonic acid, Doconexent","CC\\C=C/C/C=C\\C\\C=C/C/C=C\\C\\C=C/C/C=C\\CCC(O)=O",6.462,1,0,14]
["S6457","Flurbiprofen Axetil","f4","L3800-31","in 10mM DMSO","CFDA","N/A","N/A","COX","Immunology & Inflammation","Flurbiprofen Axetil is one of the commonly used nonsteroidal anti-inflammatory drugs (NSAIDs) that nonselectively inhibits cyclooxygenase.",330.35,"91503-79-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleck.cn/products/flurbiprofen-axetil.html","C19H19FO4","Free Base","N/A","CC(OC(C)=O)OC(=O)C(C)C1=CC=C(C(=C1)F)C2=CC=CC=C2",3.906,4,0,7]
["S6465","Tafamidis","b5","L3800-31","in 10mM DMSO","FDA,EMA","N/A","Marketed","5-HT Receptor","Neuronal Signaling","Tafamidis is a kinetic stabilizer of transthyretin (TTR) that prevents amyloidogenesis by wild-type and mutant TTRs.",308.12,"594839-88-0",{"v":31,"d":"31.00"},100.61,"<1","N/A","http://www.selleck.cn/products/tafamidis.html","C14H7Cl2NO3","Free Base","N/A","OC(=O)C1=CC=C2N=C(OC2=C1)C3=CC(=CC(=C3)Cl)Cl",4.239,3,0,2]
["S6469","Thonzylamine","e5","L3800-31","in 10mM DMSO","NDC","Martindale the Extra Pharmacopoei","N/A","AChR,Histamine Receptor","Neuronal Signaling","Thonzylamine (Neohetramine) is an antihistamine and anticholinergic drug.",286.37,"91-85-0",{"v":57,"d":"57.00"},199.04,{"v":57,"d":"57.00"},199.04,"http://www.selleck.cn/products/thonzylamine.html","C16H22N4O","Free Base","Neohetramine","COC1=CC=C(CN(CCN(C)C)C2=NC=CC=N2)C=C1",{"v":2.44,"d":"2.440"},3,0,7]
["S6476","Eicosapentaenoic Acid","a6","L3800-31","in 10mM DMSO","DMF","Martindale the Extra Pharmacopoei","Phase 3","Immunology & Inflammation related","Immunology & Inflammation","Eicosapentaenoic acid (EPA) is an omega-3 polyunsaturated fatty acid with antiinflammatory properties, and is present in fish and fish oils, including salmon, cod, and krill oils.",302.45,"10417-94-4",{"v":60,"d":"60.00"},198.38,"<1","N/A","http://www.selleck.cn/products/eicosapentaenoic-acid.html","C20H30O2","Free Base","N/A","CC/C=C\\C\\C=C/C/C=C\\C\\C=C/C/C=C\\CCCC(O)=O",5.994,1,0,13]
["S6487","fluticasone furoate","d6","L3800-31","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale the Extra Pharmacopoei","Marketed","Adrenergic Receptor","Neuronal Signaling","Fluticasone furoate (GW685698) is an inhaled corticosteroid/long-acting beta-agonist combination with a prolonged bronchodilator duration of action. It is used for the treatment of non-allergic and allergic rhinitis administered by a nasal spray.",538.58,"397864-44-7",{"v":100,"d":"100.00"},185.67,"<1","N/A","http://www.selleck.cn/products/fluticasone-furoate.html","C27H29F3O6S","free base","GW685698","CC1CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(OC(=O)C5=CC=CO5)C(=O)SCF",4.479,5,1,6]
["S6508","Mitapivat","g6","L3800-31","in 10mM DMSO","N/A","N/A","Phase 3","PKM","Metabolism","Mitapivat (AG-348) is an activator of a pyruvate kinase PKM2, an enzyme involved in glycolysis.",450.55,"1260075-17-9",{"v":90,"d":"90.00"},199.76,"<1","N/A","http://www.selleck.cn/products/mitapivat.html","C24H26N4O3S","free base","AG-348","O=C(N1CCN(CC1)CC2CC2)C3=CC=C(N[S](=O)(=O)C4=C5N=CC=CC5=CC=C4)C=C3",2.695,4,1,6]
["S6533","Briciclib","h6","L3800-31","in 10mM DMSO","N/A","N/A","Phase 1","eIF","ER stress & UPR","Briciclib (ON-014185) is a water soluble derivative of ON-013100, a small molecule that binds to and inhibits eukaryotic translation initiation factor 4E (eIF4E).",474.42,"865783-99-9",{"v":95,"d":"95.00"},200.24,"<1","N/A","http://www.selleck.cn/products/briciclib.html","C19H23O10PS","free base","ON-014185","COC1=CC(=C(/C=C/[S](=O)(=O)CC2=CC=C(OC)C(=C2)O[P](O)(O)=O)C(=C1)OC)OC",2.319,7,0,10]
["S6588","Methylprednisolone hemisuccinate","c7","L3800-31","in 10mM DMSO","FDA,CFDA,DMF,NDC,PMDA,HMA","Martindale the Extra Pharmacopoei,KP Ⅹ,USP39-NF34","N/A","Others","Others","Methylprednisolone sodium succinate is a glucocorticoid used to treat a variety health issues including severe allergic reactions, asthma, autoimmune diseases, blood disorders, gastrointestinal diseases and endocrine disorders.",474.54,"2921-57-5",{"v":95,"d":"95.00"},200.19,"<1","N/A","https://www.selleckchem.com/products/methylprednisolone-hemisuccinate-s6588.html","C26H34O8","free base","N/A","CC1CC2C3CCC(O)(C(=O)COC(=O)CCC(O)=O)C3(C)CC(O)C2C4(C)C=CC(=O)C=C14",1.736,5,1,7]
["S6611","Cyclothiazide","g7","L3800-31","in 10mM DMSO","FDA","Martindale the Extra Pharmacopoei","N/A","GABA Receptor","Neuronal Signaling","Cyclothiazide is a positive allosteric modulator of ionotropic α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-type glutamate receptors with critical roles in neurological development and function.",389.88,"2259-96-3",{"v":78,"d":"78.00"},200.06,"<1","N/A","http://www.selleck.cn/products/cyclothiazide.html","C14H16ClN3O4S2","free base","N/A","N[S](=O)(=O)C1=CC2=C(NC(N[S]2(=O)=O)C3CC4CC3C=C4)C=C1Cl",1.228,4,3,2]
["S7007","Binimetinib (MEK162)","b8","L3800-31","in 10mM DMSO","FDA,EMA,NDC,PMDA","N/A","Marketed","Apoptosis related,Autophagy,MEK","MAPK","Binimetinib (MEK162, ARRY-162, ARRY-438162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM in a cell-free assay. Binimetinib induces G1 cell cycle arrest and apoptosis in human NSCLC cell lines and induces autophagy. Phase 3.",441.23,"606143-89-9",{"v":88,"d":"88.00"},199.44,"<1","N/A","http://selleckchem.com/products/mek162.html","C17H15BrF2N4O3","free base","ARRY-162,ARRY-438162","C[N]1C=NC2=C1C=C(C(=O)NOCCO)C(=C2F)NC3=C(F)C=C(Br)C=C3",2.775,3,3,6]
["S7010","GDC-0152","d8","L3800-31","in 10mM DMSO","N/A","N/A","Phase 1","IAP","Apoptosis","GDC-0152 is a potent antagonist of XIAP-BIR3, ML-IAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 28 nM, 14 nM, 17 nM and 43 nM in cell-free assays, respectively; less affinity shown to cIAP1-BIR2 and cIAP2-BIR2. Phase 1.",498.64,"873652-48-3",{"v":99,"d":"99.00"},198.54,{"v":3,"d":"3.00"},6.02,"http://selleckchem.com/products/gdc-0152.html","C25H34N6O3S","free base","N/A","CNC(C)C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3=C(N=NS3)C4=CC=CC=C4",2.767,5,3,8]
["S7025","Embelin","h8","L3800-31","in 10mM DMSO","N/A","Martindale the Extra Pharmacopoei","N/A","Antineoplastic and Immunosuppressive Antibiotics,IAP","Apoptosis","Embelin (Embelic Acid, NSC 91874), a quinone isolated from the Japanese Ardisia herb, is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 μM in a cell-free assay.",294.39,"550-24-3",{"v":59,"d":"59.00"},200.41,"<1","N/A","http://selleckchem.com/products/embelin.html","C17H26O4","free base","Embelic Acid, NSC 91874","CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O",{"v":4.62,"d":"4.620"},2,2,10]
["S7030","RG-7112","c9","L3800-31","in 10mM DMSO","N/A","N/A","Phase 1","MDM2/MDMX,p53","Apoptosis","RG7112 (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor with HTRF IC50 of 18 nM.",726.28,"939981-39-2",{"v":100,"d":"100.00"},137.69,"<1","N/A","http://selleckchem.com/products/rg-7112.html","C38H48Cl2N4O4S","free base","RO5045337","CCOC1=C(C=CC(=C1)C(C)(C)C)C2=NC(C)(C3=CC=C(Cl)C=C3)C(C)(N2C(=O)N4CCN(CCC[S](C)(=O)=O)CC4)C5=CC=C(Cl)C=C5",7.622,5,0,10]
["S7049","Oprozomib (ONX 0912)","f9","L3800-31","in 10mM DMSO","N/A","N/A","Phase 1/2","Proteasome","Proteases","Oprozomib (ONX 0912, PR-047) is an orally bioavailable inhibitor for CT-L activity of 20S proteasome β5/LMP7 with IC50 of 36 nM/82 nM. Phase 1/2.",532.61,"935888-69-0",{"v":100,"d":"100.00"},187.75,"<1","N/A","http://selleckchem.com/products/oprozomib-onx-0912.html","C25H32N4O7S","free base","PR-047","COCC(NC(=O)C(COC)NC(=O)C1=CN=C(C)S1)C(=O)NC(CC2=CC=CC=C2)C(=O)C3(C)CO3",-0.202,8,3,14]
["S7057","LY2874455","g9","L3800-31","in 10mM DMSO","N/A","N/A","Phase 2","FGFR,VEGFR","Protein Tyrosine Kinase","LY2874455 is a pan-FGFR inhibitor with IC50 of 2.8 nM, 2.6 nM, 6.4 nM, and 6 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively, and also inhibits VEGFR2 activity with IC50 of 7 nM. Phase 1.",444.31,"1254473-64-7",{"v":88,"d":"88.00"},198.06,"<1","N/A","http://selleckchem.com/products/ly2874455.html","C21H19Cl2N5O2","free base","N/A","CC(OC1=CC=C2[NH]N=C(\\C=C\\C3=C[N](CCO)N=C3)C2=C1)C4=C(Cl)C=NC=C4Cl",4.121,4,2,7]
["S7067","Tepotinib (EMD 1214063)","b10","L3800-31","in 10mM DMSO","N/A","N/A","Phase 2","Autophagy,c-Met","Protein Tyrosine Kinase","Tepotinib (EMD 1214063, MSC2156119) is a potent and selective c-Met inhibitor with IC50 of 4 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib (EMD 1214063) induces autophagy. Phase 1.",492.57,"1100598-32-0",{"v":5,"d":"5.00"},10.15,"<1","N/A","http://selleckchem.com/products/emd-1214063.html","C29H28N6O2","free base","MSC2156119","CN1CCC(CC1)COC2=CN=C(N=C2)C3=CC=CC(=C3)CN4N=C(C=CC4=O)C5=CC(=CC=C5)C#N",3.629,5,0,7]
["S7091","Zotarolimus (ABT-578)","f10","L3800-31","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia","Marketed","FKBP,mTOR","PI3K/Akt/mTOR","Zotarolimus (ABT-578,A 179578) is an analogue of rapamycin, and inhibits FKBP-12 binding with IC50 of 2.8 nM.",966.21,"221877-54-9",{"v":100,"d":"100.00"},{"v":103.5,"d":"103.50"},"<1","N/A","http://selleckchem.com/products/zotarolimus-abt-578.html","C52H79N5O12","free base","A 179578","COC1CC(CCC1[N]2C=NN=N2)CC(C)C3CC(=O)C(C)/C=C(C)/C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC4CCC(C)C(O)(O4)C(=O)C(=O)N5CCCCC5C(=O)O3)OC",5.793,13,1,7]
["S7102","Berzosertib (VE-822)","a11","L3800-31","in 10mM DMSO","N/A","N/A","Phase 1","ATM/ATR","PI3K/Akt/mTOR","Berzosertib (VE-822, VX970, M6620) is an ATR inhibitor with IC50 of 19 nM in HT29 cells.",463.55,"1232416-25-9",{"v":36,"d":"36.00"},77.66,"<1","N/A","http://selleckchem.com/products/ve-822.html","C24H25N5O3S","free base","VX970, M6620","CNCC1=CC=C(C=C1)C2=NOC(=C2)C3=C(N)N=CC(=N3)C4=CC=C(C=C4)[S](=O)(=O)C(C)C",3.697,6,2,7]
["S7110","(+)-JQ1","d11","L3800-31","in 10mM DMSO","N/A","N/A","Phase 1","Autophagy,Epigenetic Reader Domain,NSD,Target Protein Ligand","Epigenetics","(+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+)-JQ1 suppresses cell proliferation via inducing autophagy. (+)-JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.",456.99,"1268524-70-4",{"v":91,"d":"91.00"},199.13,"<1","N/A","http://selleckchem.com/products/jq1.html","C23H25ClN4O2S","free base","N/A","CC1=C(C)C2=C(S1)[N]3C(=NN=C3C(CC(=O)OC(C)(C)C)N=C2C4=CC=C(Cl)C=C4)C",4.953,5,0,5]
["S7122","XL888","h11","L3800-31","in 10mM DMSO","N/A","N/A","Phase 1","HSP (HSP90)","Cytoskeletal Signaling","XL888 is an ATP-competitive inhibitor of HSP90 with IC50 of 24 nM. Phase 1.",503.64,"1149705-71-4",{"v":100,"d":"100.00"},198.55,"<1","N/A","http://selleckchem.com/products/xl888.html","C29H37N5O3","free base","N/A","CCC(C)NC1=C(C=C(C)C(=C1)C(=O)NC2CC3CCC(C2)N3C4=NC=C(C=C4)C(=O)C5CC5)C(N)=O",3.772,4,3,9]
["S7144","BMS-911543","c2","L3800-32","in 10mM DMSO","N/A","N/A","Phase 2","JAK","JAK/STAT","BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.",432.52,"1271022-90-2",{"v":36,"d":"36.00"},83.23,"<1","N/A","http://selleckchem.com/products/bms-911543.html","C23H28N8O","free base","N/A","CC[N]1C(=CC2=C1N=C(NC3=N[N](C)C(=C3)C)C4=C2[N](C)C=N4)C(=O)N(C5CC5)C6CC6",3.556,4,1,6]
["S7157","Ilomastat","f2","L3800-32","in 10mM DMSO","N/A","N/A","Phase 2","MMP","Proteases","Ilomastat (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MMP-14, and MMP-26 with Ki of 0.4 nM, 0.5 nM, 27 nM, 3.7 nM, 0.1 nM, 0.2 nM, 3.6 nM, 13.4 nM, 0.36 nM, respectively.",388.46,"142880-36-2",{"v":78,"d":"78.00"},200.79,"<1","N/A","http://selleckchem.com/products/gm6001.html","C20H28N4O4","free base","GM6001, Galardin","CNC(=O)C(CC1=C[NH]C2=CC=CC=C12)NC(=O)C(CC(C)C)CC(=O)NO",1.624,3,4,9]
["S7158","Abemaciclib mesylate (LY2835219)","g2","L3800-32","in 10mM DMSO","FDA,EMA,NDC,PMDA","N/A","Marketed","CDK","Cell Cycle","Abemaciclib (LY2835219) is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively. Phase 3.",{"v":602.7,"d":"602.70"},"1231930-82-7",{"v":83,"d":"83.00"},137.71,{"v":100,"d":"100.00"},165.92,"http://selleckchem.com/products/ly2835219.html","C27H32F2N8.CH4O3S","mesylate","N/A","CCN1CCN(CC1)CC2=CC=C(NC3=NC(=C(F)C=N3)C4=CC(=C5N=C(C)[N](C(C)C)C5=C4)F)N=C2.C[S](O)(=O)=O",4.543,4,1,7]
["S7169","Crenigacestat (LY3039478)","b3","L3800-32","in 10mM DMSO","N/A","N/A","Phase 1/2","Gamma-secretase,Notch","Stem Cells & Wnt","Crenigacestat (LY3039478) is an oral Notch and gamma-secretase inhibitor with IC50 of 0.41 nM for Notch.",464.44,"1421438-81-4",{"v":92,"d":"92.00"},198.09,"<1","N/A","http://selleckchem.com/products/ly3039478.html","C22H23F3N4O4","free base","N/A","CC(NC(=O)CCC(F)(F)F)C(=O)NC1C(=O)N(CCO)C2=C(C=CC=N2)C3=C1C=CC=C3",1.395,4,3,8]
["S7174","Opaganib (ABC294640)","f3","L3800-32","in 10mM DMSO","N/A","N/A","Phase 2","SPHK","Immunology & Inflammation","Opaganib (ABC294640) is an orally bioavailable and selective sphingosine kinase-2 (SphK2) inhibitor with IC50 of approximately 60 μM. Phase 1/2.",380.91,"915385-81-8",{"v":76,"d":"76.00"},199.52,"<1","N/A","http://selleckchem.com/products/abc294640.html","C23H25ClN2O","free base","N/A","ClC1=CC=C(C=C1)[C]23CC4[CH2]C(C[C](C4)(C2)C(=O)NCC5=CC=NC=C5)C3",4.265,2,1,4]
["S7192","PF-04620110","a4","L3800-32","in 10mM DMSO","N/A","N/A","Phase 1","Acyltransferase,Transferase","Metabolism","PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.",396.44,"1109276-89-2",{"v":49,"d":"49.00"},{"v":123.6,"d":"123.60"},"<1","N/A","http://selleckchem.com/products/pf-04620110.html","C21H24N4O4","free base","N/A","NC1=C2C(=O)N(CCOC2=NC=N1)C3=CC=C(C=C3)C4CCC(CC4)CC(O)=O",2.797,5,1,4]
["S7205","Idasanutlin (RG-7388)","d4","L3800-32","in 10mM DMSO","N/A","N/A","Phase 3","MDM2/MDMX","Apoptosis","Idasanutlin (RG-7388) is a potent and selective p53-MDM2 inhibitor with IC50 of 6 nM showing improved in vitro binding as well as cellular potency/selectivity.",616.48,"1229705-06-9",{"v":100,"d":"100.00"},162.21,"<1","N/A","http://selleckchem.com/products/idasanutlin-rg-7388.html","C31H29Cl2F2N3O4","free base","N/A","COC1=C(NC(=O)C2NC(CC(C)(C)C)C(C#N)(C2C3=C(F)C(=CC=C3)Cl)C4=CC=C(Cl)C=C4F)C=CC(=C1)C(O)=O",{"v":3.85,"d":"3.850"},3,2,8]
["S7252","Selinexor (KPT-330)","h4","L3800-32","in 10mM DMSO","N/A","N/A","Preregistration","CRM1","Transmembrane Transporters","Selinexor (KPT-330, ATG-010) is an orally bioavailable selective CRM1 inhibitor. Phase 2.",443.31,"1393477-72-9",{"v":88,"d":"88.00"},198.51,"<1","N/A","http://selleckchem.com/products/kpt-330.html","C17H11F6N7O","free base","ATG-010","FC(F)(F)C1=CC(=CC(=C1)C2=N[N](\\C=C/C(=O)NNC3=CN=CC=N3)C=N2)C(F)(F)F",2.345,5,2,7]
["S7262","Vidofludimus","c5","L3800-32","in 10mM DMSO","N/A","N/A","Phase 2","COVID-19,Dehydrogenase","Metabolism","Vidofludimus (SC12267, 4SC-101) is an orally active and potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 134 nM for human DHODH. Vidofludimus calcium (IMU-838) is investigated as a potential treatment option for COVID-19. Phase 2.",355.36,"717824-30-1",{"v":100,"d":"100.00"},{"v":281.4,"d":"281.40"},"<1","N/A","http://selleckchem.com/products/vidofludimus.html","C20H18FNO4","free base","SC12267, 4SC-101","COC1=CC(=CC=C1)C2=CC(=C(NC(=O)C3=C(CCC3)C(O)=O)C=C2)F",3.878,3,1,5]
["S7263","AZD1981","d5","L3800-32","in 10mM DMSO","N/A","N/A","Phase 2","GPR","Endocrinology & Hormones","AZD1981 is a potent, selective CRTh2 (DP2) receptor antagonist with IC50 of 4 nM, showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1. Phase 2.",388.87,"802904-66-1",{"v":11,"d":"11.00"},28.29,"<1","N/A","http://selleckchem.com/products/azd1981.html","C19H17ClN2O3S","free base","N/A","CC(=O)NC1=C2C(=CC=C1)[N](CC(O)=O)C(=C2SC3=CC=C(Cl)C=C3)C",3.859,2,1,5]
["S7295","Apabetalone (RVX-208)","h5","L3800-32","in 10mM DMSO","N/A","N/A","Phase 3","Epigenetic Reader Domain","Epigenetics","Apabetalone (RVX-208, RVX-000222) is a potent BET bromodomain inhibitor with IC50 of 0.510 μM for BD2 in a cell-free assay, about 170-fold selectivity over BD1. Phase 2.",{"v":370.4,"d":"370.40"},"1044870-39-4",{"v":74,"d":"74.00"},199.78,"<1","N/A","http://selleckchem.com/products/rvx-208.html","C20H22N2O5","free base","RVX-000222","COC1=CC(=C2C(=O)NC(=NC2=C1)C3=CC(=C(OCCO)C(=C3)C)C)OC",2.877,5,2,6]
["S7323","Itanapraced (CHF 5074)","d6","L3800-32","in 10mM DMSO","N/A","N/A","Phase 2","Secretase,Secretase","Proteases","Itanapraced (CHF 5074, CSP-1103) is a gamma-secretase modulator that reduces Aβ42 and Aβ40 secretion. The IC50s of CHF5074 for inhibition of COX-1 and COX-2 is above 100 μmol/L.",325.16,"749269-83-8",{"v":65,"d":"65.00"},{"v":199.9,"d":"199.90"},"<1","N/A","http://www.selleckchem.com/products/chf-5074.html","C16H11Cl2FO2","Free Base","CSP-1103","OC(=O)C1(CC1)C2=CC(=C(C=C2)C3=CC=C(Cl)C(=C3)Cl)F",5.055,1,0,3]
["S7329","IOWH032","f6","L3800-32","in 10mM DMSO","N/A","N/A","Phase 2","CFTR","Transmembrane Transporters","IOWH032 is a synthetic CFTR inhibitor with IC50 of 1.01 μM in CHO-CFTR cell based assays. Phase 2.",545.18,"1191252-49-9",{"v":100,"d":"100.00"},183.43,"<1","N/A","http://selleckchem.com/products/iowh032.html","C22H15Br2N3O4","free base","N/A","OC1=C(Br)C=C(C=C1Br)C2=NOC(=N2)C(=O)NCC3=CC=C(OC4=CC=CC=C4)C=C3",5.233,5,2,6]
["S7360","Birabresib (OTX015)","a7","L3800-32","in 10mM DMSO","N/A","N/A","Phase 2","Epigenetic Reader Domain,NSD","Epigenetics","Birabresib (OTX015, MK 8628) is a potent BET bromodomain inhibitor with EC50 ranging from 10 to 19 nM for BRD2, BRD3, and BRD4 in cell-free assays. Birabresib inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.",491.99,"202590-98-5",{"v":98,"d":"98.00"},199.19,"<1","N/A","http://selleckchem.com/products/otx015.html","C25H22ClN5O2S","free base","MK 8628","CC1=C(C)C2=C(S1)[N]3C(=NN=C3C(CC(=O)NC4=CC=C(O)C=C4)N=C2C5=CC=C(Cl)C=C5)C",4.709,4,2,4]
["S7411","Ascomycin (FK520)","d7","L3800-32","in 10mM DMSO","DMF","N/A","N/A","Anti-infection","Microbiology","Ascomycin (FK520, FR 900520, Immunomycin), an FK-506 analog, is a neutral macrolide immunosuppressant, which prevents rejection after an organ transplant. Phase 3.",792.01,"104987-12-4",{"v":100,"d":"100.00"},126.26,"<1","N/A","http://selleckchem.com/products/ascomycin-fk520.html","C43H69NO12","free base","FR 900520, Immunomycin","CCC1/C=C(C)/CC(C)CC(OC)C2OC(O)(C(C)CC2OC)C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)C(O)CC1=O)\\C(C)=C\\C4CCC(O)C(C4)OC",4.766,9,2,6]
["S7470","Triapine","a8","L3800-32","in 10mM DMSO","DMF","N/A","Phase 2","DNA/RNA Synthesis,RNR","DNA Damage/DNA Repair","Triapine (3-AP) is a potent ribonucleotide reductase (RNR) inhibitor with broad spectrum antitumor activity by inhibiting DNA synthesis. Phase 2.",195.24,"200933-27-3",{"v":20,"d":"20.00"},102.44,"<1","N/A","http://selleckchem.com/products/triapine.html","C7H9N5S","free base","3-AP","NC(=S)N/N=C/C1=NC=CC=C1N",0.331,2,3,3]
["S7513","Trelagliptin","d8","L3800-32","in 10mM DMSO","PMDA","N/A","Marketed","DPP","Proteases","Trelagliptin (SYR-472), a potent, orally active and highly selective DPP-4 inhibitor with an IC50 of 4 nM, improves glycemic control in vivo and can be used for the study of type 2 diabetes mellitus (T2DM).",357.38,"865759-25-7",{"v":71,"d":"71.00"},198.67,"<1","N/A","http://selleckchem.com/products/trelagliptin.html","C18H20FN5O2","free base","SYR-472","CN1C(=O)C=C(N2CCCC(N)C2)N(CC3=CC(=CC=C3C#N)F)C1=O",1.476,2,1,3]
["S7515","VGX-1027","e8","L3800-32","in 10mM DMSO","N/A","N/A","Phase 1","Immunology & Inflammation related","Immunology & Inflammation","VGX-1027 (GIT 27) is an orally active immunomodulator. Phase 1.",205.21,"6501-72-0",{"v":41,"d":"41.00"},{"v":199.8,"d":"199.80"},"<1","N/A","http://selleckchem.com/products/vgx-1027.html","C11H11NO3","free base","GIT 27","OC(=O)CC1CC(=NO1)C2=CC=CC=C2",1.368,3,0,3]
["S7523","Entospletinib (GS-9973)","h8","L3800-32","in 10mM DMSO","N/A","N/A","Phase 2","Syk","Angiogenesis","Entospletinib (GS-9973) is an orally bioavailable, selective Syk inhibitor with IC50 of 7.7 nM in a cell-free assay and showed 13- to >1000-fold cellular selectivity for Syk over other kinases(including Jak2, ckit, Flt3, Ret, KDR) as assessed by target protein phosphorylation or functional response.",411.46,"1229208-44-9",{"v":26,"d":"26.00"},63.19,"<1","N/A","http://selleckchem.com/products/gs-9973.html","C23H21N7O","free base","N/A","C1CN(CCO1)C2=CC=C(NC3=NC(=C[N]4C=CN=C34)C5=CC=C6C=N[NH]C6=C5)C=C2",2.949,4,2,4]
["S7541","Decernotinib (VX-509)","c9","L3800-32","in 10mM DMSO","N/A","N/A","Phase 3","JAK","JAK/STAT","Decernotinib (VX-509) is a potent and selective JAK3 inhibitor with Ki of 2.5 nM, >4-fold selectivity over JAK1, JAK2, and TYK2, respectively. Phase 2/3.",392.38,"944842-54-0",{"v":78,"d":"78.00"},198.79,"<1","N/A","http://selleckchem.com/products/decernotinib-vx-509.html","C18H19F3N6O","free base","N/A","CCC(C)(NC1=NC(=NC=C1)C2=C[NH]C3=NC=CC=C23)C(=O)NCC(F)(F)F",2.747,4,3,7]
["S7553","GDC-0623","g9","L3800-32","in 10mM DMSO","N/A","N/A","Phase 1","MEK","MAPK","GDC-0623 (G-868) is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.",456.21,"1168091-68-6",{"v":91,"d":"91.00"},199.47,"<1","N/A","http://selleckchem.com/products/gdc-0623.html","C16H14FIN4O3","free base","G-868","OCCONC(=O)C1=C(NC2=C(F)C=C(I)C=C2)[N]3C=NC=C3C=C1",2.284,3,3,6]
["S7563","AT13148","b10","L3800-32","in 10mM DMSO","N/A","N/A","Phase 1","Akt,PKA,ROCK,S6 Kinase","PI3K/Akt/mTOR","AT13148 is an oral, ATP-competitive, multi-AGC kinase inhibitor with IC50 of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively. Phase 1.",313.78,"1056901-62-2",{"v":62,"d":"62.00"},197.59,"<1","N/A","http://selleckchem.com/products/at13148.html","C17H16ClN3O","free base","N/A","NCC(O)(C1=CC=C(Cl)C=C1)C2=CC=C(C=C2)C3=C[NH]N=C3",2.491,1,2,4]
["S7594","Abscisic Acid (Dormin)","f10","L3800-32","in 10mM DMSO","NDC","N/A","N/A","Others","Endocrinology & Hormones","Abscisic Acid (Dormin, Abscisin II) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth.",264.32,"21293-29-8",{"v":52,"d":"52.00"},196.73,"<1","N/A","http://selleckchem.com/products/abscisic-acid-dormin.html","C15H20O4","free base","Abscisin II","CC(/C=C/C1(O)C(=CC(=O)CC1(C)C)C)=C/C(O)=O",2.161,2,0,3]
["S7625","Niraparib (MK-4827) tosylate","a11","L3800-32","in 10mM DMSO","FDA,EMA,NDC","N/A","Marketed","Apoptosis related,PARP","DNA Damage/DNA Repair","Niraparib tosylate (MK-4827, ZEJULA) is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. Niraparib increases formation of PARP-DNA complexes resulting in DNA damage, apoptosis, and cell death.",492.59,"1038915-73-9",{"v":98,"d":"98.00"},198.95,"<1","N/A","http://selleckchem.com/products/mk-4827-niraparib-tosylate.html","C19H20N4O.C7H8O3S","4-?methylbenzen","Niraparib tosylate, MK 4827 tosylate, ZEJULA","CC1=CC=C(C=C1)[S](O)(=O)=O.NC(=O)C2=CC=CC3=C[N](N=C23)C4=CC=C(C=C4)C5CCCNC5",4.267,2,2,4]
["S7635","Lomitapide","d11","L3800-32","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","MTP","Transmembrane Transporters","Lomitapide (AEGR-733, BMS-201038) is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia.",692.71,"182431-12-5",{"v":100,"d":"100.00"},144.36,"<1","N/A","http://selleckchem.com/products/lomitapide.html","C39H37F6N3O2","free base","AEGR-733, BMS-201038","FC(F)(F)CNC(=O)C1(CCCCN2CCC(CC2)NC(=O)C3=C(C=CC=C3)C4=CC=C(C=C4)C(F)(F)F)C5=C(C=CC=C5)C6=C1C=CC=C6",{"v":7.79,"d":"7.790"},2,2,12]
["S7645","Pilaralisib (XL147)","e11","L3800-32","in 10mM DMSO","N/A","N/A","Phase 2","PI3K","PI3K/Akt/mTOR","Pilaralisib (XL147) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ. Phase 1/2.",541.02,"934526-89-3",{"v":100,"d":"100.00"},184.84,"<1","N/A","http://selleckchem.com/products/pilaralisib-xl147.html","C25H25ClN6O4S","free base","N/A","COC1=CC(=C(Cl)C=C1)NC2=NC3=CC=CC=C3N=C2N[S](=O)(=O)C4=CC=CC(=C4)NC(=O)C(C)(C)N",4.012,6,4,8]
["S7653","PND-1186 (VS-4718)","h11","L3800-32","in 10mM DMSO","N/A","N/A","Phase 1","Apoptosis related,FAK","Angiogenesis","PND-1186 (VS-4718, SR-2156) is a reversible and selective FAK inhibitor with IC50 of 1.5 nM. PND-1186 selectively promotes tumor cell apoptosis. Phase 1.",{"v":501.5,"d":"501.50"},"1061353-68-1",{"v":24,"d":"24.00"},47.86,"<1","N/A","http://selleckchem.com/products/pnd-1186-vs-4718.html","C25H26F3N5O3","free base","SR-2156","CNC(=O)C1=CC=CC=C1NC2=CC(=NC=C2C(F)(F)F)NC3=CC=C(C=C3OC)N4CCOCC4",4.302,4,3,8]
["S7663","Ruboxistaurin (LY333531) HCl","c2","L3800-33","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","PKC","TGF-beta/Smad","Ruboxistaurin (LY333531) HCl is a β-specific protein kinase C inhibitor. It competitively and reversibly inhibits PKCβ1 and PKCβ2 with IC50 values of 4.7 and 5.9 nM respectively.",505.01,"169939-93-9",{"v":50,"d":"50.00"},99.01,"<1","N/A","http://selleckchem.com/products/ly333531.html","C28H28N4O3.HCl","hydrochloride","Ruboxistaurin hydrochloride,  LY333531 hydrochloride","Cl.CN(C)CC1CC[N]2C=C(C3=C2C=CC=C3)C4=C(C(=O)NC4=O)C5=C[N](CCO1)C6=C5C=CC=C6",3.861,3,1,2]
["S7674","Savolitinib (AZD6094)","g2","L3800-33","in 10mM DMSO","N/A","N/A","Phase 3","c-Met","Protein Tyrosine Kinase","Savolitinib (Volitinib, AZD6094, HMPL-504) is a novel, potent, and selective MET inhibitor currently in clinical development in various indications, including PRCC. The IC50 values of this compound for c-Met and p-Met are 5 nM and 3 nM, respectively. It shows exquisite selectivity for c-Met over 274 kinase.",345.36,"1313725-88-0",{"v":16,"d":"16.00"},46.33,"<1","N/A","http://selleckchem.com/products/hmpl-504-azd6094-volitinib.html","C17H15N9","free base","HMPL-504, Volitinib","CC([N]1N=NC2=NC=C(N=C12)C3=C[N](C)N=C3)C4=C[N]5C=CN=C5C=C4",1.032,6,0,3]
["S7693","Ceralasertib (AZD6738)","b3","L3800-33","in 10mM DMSO","N/A","N/A","Phase 2","ATM/ATR","PI3K/Akt/mTOR","Ceralasertib (AZD6738) is an orally active, and selective ATR kinase inhibitor with IC50 of 1 nM. Phase 1/2.",412.51,"1352226-88-0",{"v":82,"d":"82.00"},198.78,"<1","N/A","http://selleckchem.com/products/azd6738.html","C20H24N6O2S","free base","N/A","CC1COCCN1C2=NC(=NC(=C2)C3(CC3)[S](C)(=N)=O)C4=C5C=C[NH]C5=NC=C4",2.427,5,1,4]
["S7721","Monomethyl auristatin E (MMAE)","f3","L3800-33","in 10mM DMSO","DMF","N/A","N/A","ADC Cytotoxin,Microtubule Associated","Cytoskeletal Signaling","Monomethyl auristatin E (MMAE, SGD-1010) is a synthetic antineoplastic agent, which is linked to a monoclonal antibody (MAB). It is also a microtubule-disrupting agent .",717.98,"474645-27-7",{"v":100,"d":"100.00"},139.28,"<1","N/A","http://selleckchem.com/products/monomethyl-auristatin-e-mmae.html","C39H67N5O7","free base","SGD-1010","CCC(C)C(C(CC(=O)N1CCCC1C(OC)C(C)C(=O)NC(C)C(O)C2=CC=CC=C2)OC)N(C)C(=O)C(NC(=O)C(NC)C(C)C)C(C)C",{"v":3.46,"d":"3.460"},6,4,20]
["S7725","BLZ945","h3","L3800-33","in 10mM DMSO","N/A","N/A","Phase 1/2","CSF-1R","Protein Tyrosine Kinase","BLZ945(Sotuletinib) is an orally active, potent and selective CSF-1R inhibitor with IC50 of 1 nM, >1000-fold selective against its closest receptor tyrosine kinase homologs.",398.48,"953769-46-5",{"v":79,"d":"79.00"},198.25,"<1","N/A","http://selleckchem.com/products/blz945.html","C20H22N4O3S","free base","Sotuletinib","CNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(NC4CCCCC4O)S3",3.201,4,3,5]
["S7754","Gilteritinib (ASP2215)","c4","L3800-33","in 10mM DMSO","FDA,NDC,PMDA","N/A","Marketed","Axl,FLT3","Protein Tyrosine Kinase","Gilteritinib (ASP2215) is a small-molecule FLT3/AXL inhibitor with IC50 values of 0.29 nM and 0.73 nM for FLT3 and AXL, respectively. It inhibits FLT3 at an IC50 value that was approximately 800-fold more potent than the concentration required to inhibit c-KIT (230 nM).",552.71,"1254053-43-4",{"v":100,"d":"100.00"},180.93,"<1","N/A","http://selleckchem.com/products/gilteritinib-asp2215.html","C29H44N8O3","free base","N/A","CCC1=NC(=C(NC2=CC=C(N3CCC(CC3)N4CCN(C)CC4)C(=C2)OC)N=C1NC5CCOCC5)C(N)=O",2.401,5,3,9]
["S7757","6-Thio-dG","d4","L3800-33","in 10mM DMSO","N/A","N/A","Phase 2","DNA/RNA Synthesis","DNA Damage/DNA Repair","6-thio-dG (β-TGdR) is a nucleoside analog and telomerase substrate.",283.31,"789-61-7",{"v":56,"d":"56.00"},197.66,"<1","N/A","http://selleckchem.com/products/6-thio-dg.html","C10H13N5O3S","free base","β-TGdR","NC1=NC(=S)C2=C(N1)[N](C=N2)C3CC(O)C(CO)O3",-0.714,3,4,2]
["S7772","Elacridar (GF120918)","g4","L3800-33","in 10mM DMSO","N/A","N/A","Phase 1","P-gp","Transmembrane Transporters","Elacridar (GF120918, GW120918, GG918, GW0918) is a potent P-gp (MDR-1) and BCRP inhibitor.",563.64,"143664-11-3",{"v":8,"d":"8.00"},14.19,"<1","N/A","http://selleckchem.com/products/elacridar-gf120918.html","C34H33N3O5","free base","GW120918, GG918, GW0918","COC1=C2NC3=C(C=CC=C3C(=O)NC4=CC=C(CCN5CCC6=C(C5)C=C(OC)C(=C6)OC)C=C4)C(=O)C2=CC=C1",5.742,5,2,8]
["S7782","Dasatinib Monohydrate","b5","L3800-33","in 10mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia","Marketed","Bcr-Abl,c-Kit,Src","Angiogenesis","Dasatinib Monohydrate (BMS-354825) is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.",506.02,"863127-77-9",{"v":21,"d":"21.00"},{"v":41.5,"d":"41.50"},"<1","N/A","http://selleckchem.com/products/dasatinib-monohydrate.html","C22H28ClN7O3S","Monohydrate","BMS-354825 Monohydrate","O.CC1=NC(=CC(=N1)NC2=NC=C(S2)C(=O)NC3=C(C)C=CC=C3Cl)N4CCN(CCO)CC4",3.232,4,3,7]
["S7787","Docetaxel Trihydrate","f5","L3800-33","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017,IP2010","Phase 2","Microtubule Associated","Cytoskeletal Signaling","Docetaxel (RP56976, NSC 628503), an analog of paclitaxel, is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules.",861.93,"148408-66-6",{"v":100,"d":"100.00"},116.02,"<1","N/A","http://selleckchem.com/products/docetaxel-trihydrate.html","C43H53NO14.3H2O","Trihydrate","RP56976 (NSC 628503) Trihydrate","O.O.O.CC(=O)OC12COC1CC(O)C3(C)C2C(OC(=O)C4=CC=CC=C4)C5(O)CC(OC(=O)C(O)C(NC(=O)OC(C)(C)C)C6=CC=CC=C6)C(=C(C(O)C3=O)C5(C)C)C",1.964,10,4,13]
["S7796","GSK2879552 2HCl","a6","L3800-33","in 10mM DMSO","N/A","N/A","Phase 1/2","Histone Demethylase,LSD1","Epigenetics","GSK2879552 2HCl is a potent, selective, orally bioavailable, irreversible LSD1 inhibitor with Kiapp of 1.7 μM. Phase 1.",{"v":437.4,"d":"437.40"},"1902123-72-1",{"v":29,"d":"29.00"},{"v":66.3,"d":"66.30"},{"v":44,"d":"44.00"},100.59,"http://selleckchem.com/products/gsk2879552-2hcl.html","C23H28N2O2.2HCl","dihydrochloride","N/A","Cl.Cl.OC(=O)C1=CC=C(CN2CCC(CC2)CNC3CC3C4=CC=CC=C4)C=C1",1.586,1,1,7]
["S7812","Itacitinib (INCB39110)","e6","L3800-33","in 10mM DMSO","N/A","N/A","Phase 3","JAK","JAK/STAT","Itacitinib(INCB39110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.",553.51,"1334298-90-6",{"v":100,"d":"100.00"},180.67,"<1","N/A","http://selleckchem.com/products/itacitinib-incb39110.html","C26H23F4N9O","free base","N/A","FC1=C(C=CN=C1C(F)(F)F)C(=O)N2CCC(CC2)N3CC(CC#N)(C3)[N]4C=C(C=N4)C5=C6C=C[NH]C6=NC=N5",2.422,5,1,6]
["S7824","Nazartinib (EGF816)","h6","L3800-33","in 10mM DMSO","N/A","N/A","Phase 3","EGFR","Angiogenesis","Nazartinib (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro.",495.02,"1508250-71-2",{"v":99,"d":"99.00"},199.99,"<1","N/A","http://selleckchem.com/products/nazartinib-egf816-nvs-816.html","C26H31ClN6O2","free base","NVS-816","CN(C)C/C=C/C(=O)N1CCCCC(C1)[N]2C(=NC3=CC=CC(=C23)Cl)NC(=O)C4=CC(=NC=C4)C",3.705,4,1,6]
["S7834","Cyclo (-RGDfK)","c7","L3800-33","in 10mM DMSO","DMF,NDC","N/A","N/A","Integrin","Cytoskeletal Signaling","Cyclo (-RGDfK) is a potent and selective αvβ3 integrin inhibitor.",717.69,"500577-51-5",{"v":100,"d":"100.00"},139.34,{"v":84,"d":"84.00"},117.04,"http://selleckchem.com/products/cyclo-rgdfk.html","C29H42F3N9O9","free base","N/A","NCCCCC1NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CCCNC(N)=N)NC1=O.OC(=O)C(F)(F)F",-4.172,7,8,14]
["S7839","Endoxifen HCl","d7","L3800-33","in 10mM DMSO","N/A","N/A","Phase 2","Estrogen/progestogen Receptor","Endocrinology & Hormones","Endoxifen HCl, the active metabolite of Tamoxifen, ia a potent and selective estrogen receptor antagonist. Phase 2.",409.95,"1032008-74-4",{"v":74,"d":"74.00"},180.51,"<1","N/A","http://selleckchem.com/products/endoxifen-hcl.html","C25H28ClNO2","Hydrochloride","N/A","Cl.CC/C(C1=CC=CC=C1)=C(C2=CC=C(O)C=C2)/C3=CC=C(OCCNC)C=C3",5.923,1,2,8]
["S7852","Eliglustat","g7","L3800-33","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Glucosylceramide Synthase","Metabolism","Eliglustat (GENZ-112638) inhibits glucosylceramide synthase(GCS) (IC50=20 nM in intact MDCK cells), thus reducing the load of glucosylceramide influx into the lysosome.",404.54,"491833-29-5",{"v":80,"d":"80.00"},197.76,"<1","N/A","http://selleckchem.com/products/eliglustat.html","C23H36N2O4","Tartrate","GENZ-112638","CCCCCCCC(=O)NC(CN1CCCC1)C(O)C2=CC=C3OCCOC3=C2",3.808,3,2,11]
["S7858","Dibutyryl-cAMP (Bucladesine)","c8","L3800-33","in 10mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia","N/A","PDE,PKA","GPCR & G Protein","Dibutyryl-cAMP (Bucladesine, dbcAMP) is a cell-permeable PKA activator by mimicing the action of endogenous cAMP. Dibutyryl-cAMP (Bucladesine) is also a phosphodiesterase (PDE) inhibitor.",491.37,"16980-89-5",{"v":98,"d":"98.00"},199.44,{"v":98,"d":"98.00"},199.44,"http://selleckchem.com/products/dibutyryl-camp-bucladesine.html","C18H23N5NaO8P","sodium salt","dbcAMP","CCCC(=O)NC1=NC=NC2=C1N=C[N]2C3OC4CO[P](=O)(O[Na])OC4C3OC(=O)CCC",1.028,10,1,9]
["S7875","NVP-CGM097","f8","L3800-33","in 10mM DMSO","NA","NA","Phase 1","MDM2/MDMX","Apoptosis","NVP-CGM097 is a highly potent and selective MDM2 inhibitor with Ki value of 1.3 nM for hMDM2 in TR-FRET assay. It binds to the p53 binding-site of the Mdm2 protein, disrupting the interaction between both proteins, leading to an activation of the p53 pathway.",659.26,"1313363-54-0",{"v":65,"d":"65.00"},{"v":98.6,"d":"98.60"},"<1","N/A","http://selleckchem.com/products/nvp-cgm097.html","C38H47ClN4O4","free base","CGM-097","COC1=CC2=C(C=C1OC(C)C)C(N(C(=O)C2)C3=CC=C(C=C3)N(C)CC4CCC(CC4)N5CCN(C)C(=O)C5)C6=CC=C(Cl)C=C6",6.455,4,0,9]
["S7891","CC-115","a9","L3800-33","in 10mM DMSO","NA","NA","Phase 1","DNA-PK,mTOR","DNA Damage/DNA Repair","CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR) with IC50 values of 0.013 μM and 0.021 μM, respectively. It has potential antineoplastic activity.",336.35,"1228013-15-7",{"v":67,"d":"67.00"},{"v":199.2,"d":"199.20"},"<1","N/A","http://selleckchem.com/products/cc-115.html","C16H16N8O","free base","N/A","CCN1C(=O)CNC2=NC=C(N=C12)C3=C(C)N=C(C=C3)C4=N[NH]C=N4",0.664,6,2,3]
["S7935","Y-39983 HCl","e9","L3800-33","in 10mM DMSO","DMF","N/A","Phase 2","ROCK","Cell Cycle","Y-39983 HCl (Y-33075) is a selective rho-associated protein kinase(ROCK) inhibitor with an IC50 of 3.6 nM.",353.25,"173897-44-4",{"v":63,"d":"63.00"},178.34,{"v":63,"d":"63.00"},178.34,"http://selleckchem.com/products/y-39983-hcl.html","C16H16N4O.2HCl","dihydrochloride","Y-33075 HCl","Cl.Cl.CC(N)C1=CC=C(C=C1)C(=O)NC2=C3C=C[NH]C3=NC=C2",2.204,2,3,3]
["S7938","GSK2292767","h9","L3800-33","in 10mM DMSO","NA","NA","Phase 1","PI3K","PI3K/Akt/mTOR","GSK2292767 is a potent and selective PI3Kδ inhibitor.",512.58,"1254036-66-2",{"v":100,"d":"100.00"},195.09,"<1","N/A","http://selleckchem.com/products/gsk2292767.html","C24H28N6O5S","free base","N/A","COC1=C(N[S](C)(=O)=O)C=C(C=N1)C2=CC3=C(C=N[NH]3)C(=C2)C4=NC=C(CN5CC(C)OC(C)C5)O4",1.692,8,2,7]
["S7953","ETC-1002","c10","L3800-33","in 10mM DMSO","N/A","N/A","Phase 3","AMPK,ATP-citrate lyase,LDL","PI3K/Akt/mTOR","ETC-1002 (Bempedoic acid, ESP-55016),also known as Bempedoic acid, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies.ETC-1002 is an activator of hepatic AMP-activated protein kinase (AMPK). It has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM).",344.49,"738606-46-7",{"v":68,"d":"68.00"},197.39,"<1","N/A","http://selleckchem.com/products/etc-1002.html","C19H36O5","free base","Bempedoic acid, ESP-55016","CC(C)(CCCCCC(O)CCCCCC(C)(C)C(O)=O)C(O)=O",{"v":5.18,"d":"5.180"},2,1,14]
["S7960","Larotrectinib (LOXO-101) sulfate","e10","L3800-33","in 10mM DMSO","FDA,NDC","N/A","Marketed","Apoptosis related,Trk receptor","Protein Tyrosine Kinase","Larotrectinib sulfate (LOXO-101, ARRY-470) is an oral potent and selective ATP-competitive inhibitor of tropomyosin receptor kinases (TRK). Larotrectinib inhibition of TRKs induces cellular apoptosis and G1 cell-cycle arrest.",526.51,"1223405-08-0",{"v":100,"d":"100.00"},189.93,"<1","N/A","http://selleckchem.com/products/loxo-101.html","C21H22F2N6O2.H2SO4","sulfate","ARRY-470, Larotrectinib","OC1CCN(C1)C(=O)NC2=C3N=C(C=C[N]3N=C2)N4CCCC4C5=CC(=CC=C5F)F.O[S](O)(=O)=O",1.374,3,2,3]
["S7966","AZD8835","h10","L3800-33","in 10mM DMSO","NA","NA","Phase 1","PI3K","PI3K/Akt/mTOR","AZD8835 ia a novel mixed inhibitor of PI3Kα and PI3Kδ with IC50 of 6.2 nM and 5.7 nM, respectively, also with selectivity against PI3Kβ (IC50=431 nM) and PI3Kγ (IC50=90 nM).",469.54,"1620576-64-8",{"v":93,"d":"93.00"},198.07,"<1","N/A","http://selleckchem.com/products/azd8835.html","C22H31N9O3","free base","N/A","CC[N]1N=C(N=C1C2=CN=C(N)C(=N2)C3=NN=C(O3)C(C)(C)C)C4CCN(CC4)C(=O)CCO",0.942,8,2,7]
["S7979","FG-2216","d11","L3800-33","in 10mM DMSO","N/A","N/A","Phase 2","HIF","Angiogenesis","FG-2216 is a potent, and orally active HIF prolyl 4-hydroxylase inhibitor with IC50 of 3.9 μM for PHD2. Phase 2.",280.66,"223387-75-5",{"v":56,"d":"56.00"},199.53,"<1","N/A","http://selleckchem.com/products/fg-2216.html","C12H9ClN2O4","free base","N/A","OC(=O)CNC(=O)C1=C(O)C2=CC=CC=C2C(=N1)Cl",1.337,3,2,3]
["S7998","Entrectinib (RXDX-101)","f11","L3800-33","in 10mM DMSO","N/A","N/A","Phase 3","ALK,Autophagy,ROS1,Trk receptor","Protein Tyrosine Kinase","Entrectinib (RXDX-101, NMS-E628) is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. Entrectinib (RXDX-101) induces autophagy. Phase 2.",560.64,"1108743-60-7",{"v":100,"d":"100.00"},178.37,"<1","N/A","http://selleckchem.com/products/entrectinib-rxdx-101.html","C31H34F2N6O2","free base","NMS-E628","CN1CCN(CC1)C2=CC=C(C(=O)NC3=N[NH]C4=C3C=C(CC5=CC(=CC(=C5)F)F)C=C4)C(=C2)NC6CCOCC6",4.952,3,3,7]
["S8015","Agerafenib (RXDX-105)","a2","L3800-34","in 10mM DMSO","N/A","N/A","Phase 1","c-Kit,c-RET,CSF-1R,PDGFR,Raf","MAPK","Agerafenib (RXDX-105, CEP-32496) is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret (c-Ret), PDGFRβ and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. Phase 1/2.",517.46,"1188910-76-0",{"v":9,"d":"9.00"},17.39,"<1","N/A","http://selleckchem.com/products/cep-32496.html","C24H22F3N5O5","free base","CEP-32496","COC1=CC2=NC=NC(=C2C=C1OC)OC3=CC(=CC=C3)NC(=O)NC4=NOC(=C4)C(C)(C)C(F)(F)F",5.288,8,2,8]
["S8022","Empagliflozin (BI 10773)","e2","L3800-34","in 10mM DMSO","FDA,DMF,EMA,NDC","N/A","Marketed","SGLT","GPCR & G Protein","Empagliflozin (BI-10773) is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. Phase 3.",450.91,"864070-44-0",{"v":90,"d":"90.00"},{"v":199.6,"d":"199.60"},"<1","N/A","http://selleckchem.com/products/empagliflozin-bi10773.html","C23H27ClO7","free base","N/A","OCC1OC(C(O)C(O)C1O)C2=CC(=C(Cl)C=C2)CC3=CC=C(OC4CCOC4)C=C3",1.839,3,4,6]
["S8034","Apremilast (CC-10004)","h2","L3800-34","in 10mM DMSO","FDA,DMF,EMA,NDC","N/A","Marketed","PDE,TNF-alpha","Metabolism","Apremilast (CC-10004) is a potent and orally active PDE4 and TNF-α inhibitor with IC50 of 74 nM and 77 nM, respectively.",{"v":460.5,"d":"460.50"},"608141-41-9",{"v":92,"d":"92.00"},199.78,"<1","N/A","http://selleckchem.com/products/apremilast-cc-10004.html","C22H24N2O7S","free base","CC-10004","CCOC1=C(OC)C=CC(=C1)C(C[S](C)(=O)=O)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(C)=O",1.509,7,1,8]
["S8041","Cobimetinib (GDC-0973)","c3","L3800-34","in 10mM DMSO","FDA,NDC,EMA","N/A","Marketed","Apoptosis related,MEK","MAPK","Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, showing more than 100-fold selectively for MEK1 over MEK2 and showed no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Cobimetinib induces apoptosis. Phase 3.",531.31,"934660-93-2",{"v":100,"d":"100.00"},188.21,"<1","N/A","http://selleckchem.com/products/cobimetinib-gdc-0973-rg7420.html","C21H21F3IN3O2","free base","RG7420,XL518","OC1(CN(C1)C(=O)C2=C(NC3=CC=C(I)C=C3F)C(=C(F)C=C2)F)C4CCCCN4",3.701,1,2,4]
["S8048","Venetoclax (ABT-199)","d3","L3800-34","in 10mM DMSO","FDA,DMF,EMA,NDC","N/A","Marketed","Autophagy,Bcl-2","Apoptosis","Venetoclax (ABT-199, GDC-0199) is a Bcl-2-selective inhibitor with Ki of <0.01 nM in cell-free assays, >4800-fold more selective versus Bcl-xL and Bcl-w, and no activity to Mcl-1. Venetoclax is reported to induce cell growth suppression, apoptosis, cell cycle arrest, and autophagy in triple negative breast cancer MDA-MB-231 cells. Phase 3.",868.44,"1257044-40-8",{"v":100,"d":"100.00"},115.15,"<1","N/A","http://selleckchem.com/products/abt-199.html","C45H50ClN7O7S","free base","GDC-0199","CC1(C)CCC(=C(C1)C2=CC=C(Cl)C=C2)CN3CCN(CC3)C4=CC(=C(C=C4)C(=O)N[S](=O)(=O)C5=CC=C(NCC6CCOCC6)C(=C5)[N+]([O-])=O)OC7=CN=C8[NH]C=CC8=C7",{"v":7.94,"d":"7.940"},6,3,13]
["S8056","Lomeguatrib","g3","L3800-34","in 10mM DMSO","N/A","N/A","Phase 2","DNA alkylator","DNA Damage/DNA Repair","Lomeguatrib (PaTrin-2) is a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase with IC50 of 5 nM.",326.17,"192441-08-0",{"v":65,"d":"65.00"},199.28,"<1","N/A","http://selleckchem.com/products/lomeguatrib.html","C10H8BrN5OS","free base","PaTrin-2","NC1=NC2=C([NH]C=N2)C(=N1)OCC3=CC(=CS3)Br",2.131,4,2,3]
["S8078","Bardoxolone Methyl","c4","L3800-34","in 10mM DMSO","EMA","N/A","Marketed","Apoptosis related,Autophagy,Ferroptosis,IκB/IKK,NF-κB,Nrf2","NF-κB","Bardoxolone Methyl (RTA 402, TP-155, NSC 713200, CDDO Methyl Ester, CDDO-Me) is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities; Also a potent Nrf2 activator and nuclear factor-κB (NF-κB) inhibitor. Bardoxolone Methyl abrogates ferroptosis. Bardoxolone methyl induces apoptosis and autophagy in cancer cells.",505.69,"218600-53-4",{"v":21,"d":"21.00"},41.53,"<1","N/A","http://selleckchem.com/products/bardoxolone-methyl.html","C32H43NO4","free base","RTA 402, TP-155, NSC 713200, CDDO Methyl Ester, CDDO-Me","COC(=O)C12CCC(C)(C)CC1C3C(=O)C=C4C(C)(CCC5C(C)(C)C(=O)C(=CC45C)C#N)C3(C)CC2",5.798,4,0,2]
["S8103","Sotagliflozin (LX4211)","f4","L3800-34","in 10mM DMSO","N/A","N/A","Preregistration","SGLT","GPCR & G Protein","Sotagliflozin (LX4211, LP-802034) is an oral dual SGLT1/SGLT2 inhibitor with IC50 of 36 nM and 1.8 nM, respectively. Phase 3.",424.94,"1018899-04-1",{"v":84,"d":"84.00"},197.67,"<1","N/A","http://selleckchem.com/products/sotagliflozin-lx4211.html","C21H25ClO5S","free base","LP-802034","CCOC1=CC=C(CC2=C(Cl)C=CC(=C2)C3OC(SC)C(O)C(O)C3O)C=C1",3.734,2,3,6]
["S8117","GMX1778 (CHS828)","a5","L3800-34","in 10mM DMSO","N/A","N/A","Phase 1","Apoptosis related,NAMPT","Metabolism","GMX1778 (CHS828) is a potent and specific inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) with IC50 and Kd of < 25 nM and 120 nM, respectively. GMX1778 induces programmed cell death with apoptotic features. Phase 1.",371.86,"200484-11-3",{"v":74,"d":"74.00"},{"v":199,"d":"199.00"},"<1","N/A","http://selleckchem.com/products/gmx1778-chs828.html","C19H22ClN5O","free base","N/A","ClC1=CC=C(OCCCCCCNC(NC2=CC=NC=C2)=NC#N)C=C1",{"v":3.84,"d":"3.840"},3,2,11]
["S8136","Sivelestat (ONO-5046)","e5","L3800-34","in 10mM DMSO","DMF,PMDA","Martindale:The Extra Pharmacopoeia,JP17","Marketed","Serine Protease","Proteases","Sivelestat (ONO5046, LY544349, EI546) is a potent and selective inhibitor of neutrophil elastase with IC50 of 44nM. It almost shows no activity at a range of other proteases.",434.46,"127373-66-4",{"v":86,"d":"86.00"},197.95,"<1","N/A","http://selleckchem.com/products/sivelestat-ono-5046.html","C20H22N2O7S","Free Base","ONO5046, LY544349, EI546","CC(C)(C)C(=O)OC1=CC=C(C=C1)[S](=O)(=O)NC2=CC=CC=C2C(=O)NCC(O)=O",2.321,6,2,9]
["S8163","Paxalisib (GDC-0084)","h5","L3800-34","in 10mM DMSO","N/A","N/A","Phase 2","mTOR,PI3K","PI3K/Akt/mTOR","Paxalisib (GDC-0084, RG7666) is a brain penetrant inhibitor of PI3K and mTOR with Kiapp values of 2 nM, 46 nM, 3 nM, 10 nM and 70 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR.",382.42,"1382979-44-3",{"v":8,"d":"8.00"},20.92,"<1","N/A","http://selleckchem.com/products/gdc-0084.html","C18H22N8O2","free base","RG7666","CC1(C)OCC[N]2C3=C(N=C12)C(=NC(=N3)C4=CN=C(N)N=C4)N5CCOCC5",0.588,7,1,2]
["S8166","tirabrutinib(ONO-4059) hydrochloride","a6","L3800-34","in 10mM DMSO","N/A","N/A","Phase 2","BTK","Angiogenesis","Tirabrutinib Hydrochloride (ONO-4059, GS-4059) is a highly potent and selective BTK inhibitor with an IC50 of 2.2 nM.",490.94,"1439901-97-9",{"v":98,"d":"98.00"},199.62,"<1","N/A","http://selleckchem.com/products/ono-4059-gs-4059.html","C25H22N6O3.HCl","hydrochloride","GS-4059","Cl.CC#CC(=O)N1CCC(C1)N2C(=O)N(C3=CC=C(OC4=CC=CC=C4)C=C3)C5=C(N)N=CN=C25",3.706,5,1,5]
["S8173","Verubecestat (MK-8931) Trifluoroacetate","d6","L3800-34","in 10mM DMSO","N/A","N/A","Phase 3","BACE","Neuronal Signaling","Verubecestat (MK-8931) Trifluoroacetate is a potent and selective beta-secretase inhibitor and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor.",523.43,"2095432-65-6",{"v":81,"d":"81.00"},154.75,"<1","N/A","http://selleckchem.com/products/verubecestat-mk-8931.html","C19H18F5N5O5S","Trifluoroacetat","MK-8931","CN1C(=N)NC(C)(C[S]1(=O)=O)C2=CC(=CC=C2F)NC(=O)C3=CC=C(F)C=N3.OC(=O)C(F)(F)F",2.198,5,2,4]
["S8193","Lanabecestat (AZD3293)","g6","L3800-34","in 10mM DMSO","N/A","N/A","Phase 3","BACE","Neuronal Signaling","Lanabecestat (AZD3293, LY3314814) is an oral beta-secretase 1 cleaving enzyme (BACE) inhibitor with an inhibitory constant Ki  of 0.4 nM.",412.53,"1383982-64-6",{"v":82,"d":"82.00"},198.77,"<1","N/A","http://selleckchem.com/products/azd3293-ly3314814.html","C26H28N4O","free base","LY3314814","COC1CCC2(CC1)CC3=C(C=C(C=C3)C4=CN=CC(=C4)C#CC)C25N=C(C)C(=N5)N",3.882,4,1,3]
["S8206","Ivosidenib (AG-120)","c7","L3800-34","in 10mM DMSO","FDA,NDC","N/A","Marketed","Dehydrogenase","Metabolism","Ivosidenib (AG-120) is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity.",582.96,"1448347-49-6",{"v":100,"d":"100.00"},171.54,"<1","N/A","http://selleckchem.com/products/ag-120-Ivosidenib.html","C28H22ClF3N6O3","free base","N/A","FC1=CN=CC(=C1)N(C(C(=O)NC2CC(F)(F)C2)C3=C(Cl)C=CC=C3)C(=O)C4CCC(=O)N4C5=NC=CC(=C5)C#N",3.004,5,1,7]
["S8234","RS-1","f7","L3800-34","in 10mM DMSO","N/A","N/A","Phase 2","CRISPR/Cas9,RAD51","DNA Damage/DNA Repair","RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51. It is an HDR(homology-directed repair) enhancer that enhances Cas9- and TALEN-mediated knock-in efficiency in rabbit embryos both in vitro and in vivo.",524.23,"312756-74-4",{"v":100,"d":"100.00"},190.76,"<1","N/A","http://selleckchem.com/products/rs-1.html","C20H16Br2N2O3S","free base","N/A","BrC1=CC=C(NC(=O)C2=CC=C(Br)C(=C2)[S](=O)(=O)NCC3=CC=CC=C3)C=C1",4.606,3,2,6]
["S8253","CCT245737","a8","L3800-34","in 10mM DMSO","N/A","N/A","Phase 2","Chk","Cell Cycle","CCT245737 (SRA737, PNT-737) is an orally active CHK1 inhibitor with The IC50 of 1.4 nM. It exhibits >1,000-fold selectivity against CHK2 and CDK1.",379.34,"1489389-18-5",{"v":75,"d":"75.00"},197.71,"<1","N/A","http://selleckchem.com/products/cct245737.html","C16H16F3N7O","free base","SRA737, PNT-737","FC(F)(F)C1=CN=C(NC2=CN=C(C=N2)C#N)C=C1NCC3CNCCO3",{"v":1.46,"d":"1.460"},4,3,6]
["S8294","Olmutinib (BI 1482694)","e8","L3800-34","in 10mM DMSO","marketed in South Korea","N/A","N/A","BTK,EGFR","Protein Tyrosine Kinase","Olmutinib (BI 1482694) is a novel third-generation epidermal growth factor receptor (EGFR) mutation-specific tyrosine kinase inhibitor (TKI). Also a potent inhibitor of Bruton's tyrosine kinase.",486.59,"1353550-13-6",{"v":97,"d":"97.00"},199.35,"<1","N/A","http://selleckchem.com/products/olmutinib-hm61713-bi-1482694.html","C26H26N6O2S","free base","HM61713","CN1CCN(CC1)C2=CC=C(NC3=NC(=C4SC=CC4=N3)OC5=CC=CC(=C5)NC(=O)C=C)C=C2",5.449,4,2,7]
["S8322","Samotolisib (LY3023414)","h8","L3800-34","in 10mM DMSO","N/A","N/A","Phase 2","DNA-PK,mTOR,PI3K","PI3K/Akt/mTOR","Samotolisib (LY3023414, GTPL8918) is an oral ATP competitive inhibitor of the class I PI3K isoforms, mTOR and DNA-PK.",406.48,"1386874-06-1",{"v":47,"d":"47.00"},115.63,"<1","N/A","http://selleckchem.com/products/ly3023414.html","C23H26N4O3","free base","GTPL8918","COC(C)CN1C(=O)N(C)C2=C1C3=CC(=CC=C3N=C2)C4=CC(=CN=C4)C(C)(C)O",1.883,4,0,5]
["S8330","Eganelisib (IPI-549)","a9","L3800-34","in 10mM DMSO","N/A","N/A","Phase 2","PI3K","PI3K/Akt/mTOR","Eganelisib (IPI-549) is a potent inhibitor of PI3K-γ with >100-fold selectivity over other lipid and protein kinases. The biochemical IC50 for PI3K-γ is 16 nM.",528.56,"1693758-51-8",{"v":100,"d":"100.00"},189.19,"<1","N/A","http://selleckchem.com/products/ipi-549.html","C30H24N8O2","free base","N/A","CC(NC(=O)C1=C2N=CC=C[N]2N=C1N)C3=CC4=CC=CC(=C4C(=O)N3C5=CC=CC=C5)C#CC6=C[N](C)N=C6",2.732,5,2,6]
["S8339","Miransertib (ARQ 092) HCl","c9","L3800-34","in 10mM DMSO","N/A","N/A","Phase 1/2","Akt","PI3K/Akt/mTOR","Miransertib (ARQ 092) HCl is a novel, orally bioavailable and selective AKT pathway inhibitor exhibiting a manageable safety profile among patients with advanced solid tumors.",468.98,"1313883-00-9",{"v":75,"d":"75.00"},159.92,"<1","N/A","http://selleckchem.com/products/arq-092.html","C27H25ClN6","hydrochloride","Miransertib","Cl.NC1=NC=CC=C1C2=NC3=CC=C(N=C3[N]2C4=CC=C(C=C4)C5(N)CCC5)C6=CC=CC=C6",{"v":4.98,"d":"4.980"},3,2,4]
["S8362","Tucatinib","f9","L3800-34","in 10mM DMSO","N/A","N/A","Phase 2","EGFR,HER2","Protein Tyrosine Kinase","Tucatinib (Irbinitinib, ONT-380, ARRY-380) is an oral, potent, selective, reversible and ATP-competitive small-molecule inhibitor of ErbB-2 (also called HER2) with IC50s of 8 nM and 7 nM for ErbB-2 and p95 HER2, respectively in cell-based assays, showing ~500-fold selective for HER2 vs EGFR. It has potential antineoplastic activity.",480.52,"937263-43-9",{"v":96,"d":"96.00"},199.78,"<1","N/A","http://selleckchem.com/products/arry-380-ont-380.html","C26H24N8O2","free base","Irbinitinib, ONT-380, ARRY-380","CC1=CC(=CC=C1OC2=CC3=NC=N[N]3C=C2)NC4=NC=NC5=CC=C(NC6=NC(C)(C)CO6)C=C45",4.744,7,2,6]
["S8397","Eltanexor (KPT-8602)","b10","L3800-34","in 10mM DMSO","N/A","N/A","Phase 1/2","CRM1","Transmembrane Transporters","Eltanexor (KPT-8602, ONO-7706，ATG-016) is a second-generation, orally bioavailable XPO1 (also known as CRM1) inhibitor with IC50 values of 20−211 nM in 10 AML lines after 3 days exposure.",428.29,"1642300-52-4",{"v":85,"d":"85.00"},198.46,"<1","N/A","http://selleckchem.com/products/kpt-8602.html","C17H10F6N6O","free base","ONO-7706，ATG-016","NC(=O)/C(=C/[N]1C=NC(=N1)C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)C3=CN=CN=C3",2.002,5,1,6]
["S8404","S49076","e10","L3800-34","in 10mM DMSO","N/A","N/A","Phase 1/2","Axl,c-Met,FGFR,Mertk","Protein Tyrosine Kinase","S49076 is a novel, potent inhibitor of Met (c-Met), AXL/MER, and FGFR1/2/3 with IC50 values below 20 nmol/L.",{"v":438.5,"d":"438.50"},"1265965-22-7",{"v":87,"d":"87.00"},{"v":198.4,"d":"198.40"},"<1","N/A","http://selleckchem.com/products/s49076.html","C22H22N4O4S","free base","N/A","O=C1CSC(=O)N1CC2=CC=C3NC(=O)C(=C\\C4=CC(=C[NH]4)CN5CCOCC5)/C3=C2",1.882,4,2,5]
["S8419","Stenoparib (E7449)","a11","L3800-34","in 10mM DMSO","N/A","N/A","Phase 2","PARP","DNA Damage/DNA Repair","Stenoparib (E7449, 2X-121, MGI25036) is an orally bioavailable, brain penetrable, small molecule dual inhibitor of PARP1/2 and also inhibits PARP5a/5b, otherwise known as tankyrase1 and 2 (TNKS1/2), important regulators of canonical Wnt/β-catenin signaling. It has IC50 values of 1.0 and 1.2 nM for PARP1 and 2, respectively.",317.34,"1140964-99-3",{"v":4,"d":"4.00"},{"v":12.6,"d":"12.60"},"<1","N/A","http://selleckchem.com/products/e7449.html","C18H15N5O","free base","2X-121, MGI25036","O=C1NN=C2NC(=NC3=C2C1=CC=C3)CN4CC5=C(C4)C=CC=C5",1.436,3,2,2]
["S8459","TAK-063","d11","L3800-34","in 10mM DMSO","N/A","N/A","Phase 2","PDE","Metabolism","TAK-063 (Balipodect) is a novel and selective phosphodiesterase 10A(PDE10A) inhibitor with an IC50 of 0.30 nM.",428.42,"1238697-26-1",{"v":85,"d":"85.00"},{"v":198.4,"d":"198.40"},"<1","N/A","http://selleckchem.com/products/tak-063.html","C23H17FN6O2","free base","Balipodect","COC1=CN(N=C(C1=O)C2=CC=N[N]2C3=CC=CC=C3)C4=CC=C(C=C4F)[N]5C=CC=N5",3.983,5,0,5]
["S8484","GSK2982772","g11","L3800-34","in 10mM DMSO","N/A","N/A","Phase 2","RIP kinase,TNF-alpha","Apoptosis","GSK2982772 is an ATP competitive receptor-interacting protein-1 (RIP1) kinase (RIPK1) inhibitor with the IC50 value of 16 nM. It has exquisite kinase specificity and excellent activity in blocking many TNF-dependent cellular responses.",{"v":377.4,"d":"377.40"},"1622848-92-3",{"v":75,"d":"75.00"},198.73,"<1","N/A","http://selleckchem.com/products/gsk2982772.html","C20H19N5O3","free base","N/A","CN1C(=O)C(COC2=CC=CC=C12)NC(=O)C3=N[NH]C(=N3)CC4=CC=CC=C4",1.639,5,2,4]
["S8503","Fisogatinib (BLU-554)","h11","L3800-34","in 10mM DMSO","N/A","N/A","Phase 2","FGFR","Angiogenesis","Fisogatinib (BLU-554) is a potent, highly-selective, oral FGFR4 inhibitor with an IC50 value of 5 nM. The IC50s for FGFR1-3 is 624-2203 nM.",503.38,"1707289-21-1",{"v":100,"d":"100.00"},198.66,"<1","N/A","http://selleckchem.com/products/blu-554.html","C24H24Cl2N4O4","free base","N/A","COC1=CC(=C(Cl)C(=C1Cl)C2=CC3=C(C=C2)N=C(NC4COCCC4NC(=O)C=C)N=C3)OC",4.229,6,2,7]
["S8526","GDC-0575 (ARRY-575)","c2","L3800-35","in 10mM DMSO","N/A","N/A","Phase 1","Chk","Cell Cycle","GDC-0575 (ARRY-575, RG7741) is a potent and selective CHK1 inhibitor with an IC50 of 1.2 nM.",378.27,"1196541-47-5",{"v":75,"d":"75.00"},198.27,"<1","N/A","http://www.selleckchem.com/products/gdc-0575.html","C16H20BrN5O","Free Base","RG7741","NC1CCCN(C1)C2=C(Br)C=NC3=C2C(=C[NH]3)NC(=O)C4CC4",1.621,2,3,3]
["S8539","TAS-102","f2","L3800-35","in 10mM DMSO","FDA","N/A","Marketed","DNA/RNA Synthesis,Thymidylate Synthase","DNA Damage/DNA Repair","TAS-102 (Trifluridine-Tipiracil Hydrochloride Mixture) is an orally administered combination of a thymidine-based nucleic acid analogue, trifluridine, and a thymidine phosphorylase inhibitor, tipiracil hydrochloride.",435.76,"733030-01-8",{"v":100,"d":"100.00"},114.74,{"v":15,"d":"15.00"},17.21,"http://selleckchem.com/products/tas-102.html","C10H11F3N2O5.0.5C9H11ClN4O2.0.5HCl","hydrochloride","Trifluridine-Tipiracil Hydrochloride Mixture","Cl.OCC1OC(CC1O)N2C=C(C(=O)NC2=O)C(F)(F)F.OCC3OC(CC3O)N4C=C(C(=O)NC4=O)C(F)(F)F.ClC5=C(CN6CCCC6=N)NC(=O)NC5=O",-1.951,8,8,8]
["S8560","Seletalisib (UCB-5857)","b3","L3800-35","in 10mM DMSO","N/A","N/A","Phase 3","PI3K","PI3K/Akt/mTOR","Seletalisib (UCB-5857) is a novel small-molecule inhibitor of PI3Kδ with an IC50 value of 12 nM and shows significant selectivity to PI3Kδ with respect to the other class I PI3K isoforms (between 24- and 303-fold).",482.85,"1362850-20-1",{"v":97,"d":"97.00"},200.89,"<1","N/A","http://www.selleckchem.com/products/seletalisib-ucb-5857.html","C23H14ClF3N6O","Free Base","N/A","[O-][N+]1=CC=CC(=C1)C2=NC3=C(Cl)C=CC=C3C=C2C(NC4=C5N=CC=CC5=NC=N4)C(F)(F)F",4.436,4,1,5]
["S8565","Omarigliptin (MK-3102)","e3","L3800-35","in 10mM DMSO","PMDA","N/A","Marketed","DPP","Proteases","Omarigliptin (MK-3102) is a competitive, reversible inhibitor of DPP-4 (IC50 = 1.6 nM, Ki = 0.8 nM). It is highly selective over all proteases tested (IC50 > 67 μM), including QPP, FAP, PEP, DPP8, and DPP9 and has weak ion channel activity (IC50 > 30 μM at IKr, Caγ1.2, and Naγ1.5).",398.43,"1226781-44-7",{"v":79,"d":"79.00"},198.28,"<1","N/A","http://selleckchem.com/products/omarigliptin-mk-3102.html","C17H20F2N4O3S","free base","N/A","C[S](=O)(=O)[N]1C=C2CN(CC2=N1)C3COC(C(N)C3)C4=C(F)C=CC(=C4)F",1.098,4,1,3]
["S8573","Sitravatinib (MGCD516)","a4","L3800-35","in 10mM DMSO","N/A","N/A","Phase 2","Axl,c-Kit,Ephrin receptor,Trk receptor,VEGFR","Protein Tyrosine Kinase","Sitravatinib (MGCD516, MG-516) is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl.",629.68,"1123837-84-2",{"v":100,"d":"100.00"},158.81,"<1","N/A","http://selleckchem.com/products/sitravatinib-mgcd516.html","C33H29F2N5O4S","free base","MG-516","COCCNCC1=CC=C(N=C1)C2=CC3=C(S2)C(=CC=N3)OC4=CC=C(NC(=O)C5(CC5)C(=O)NC6=CC=C(F)C=C6)C=C4F",5.029,6,3,12]
["S8581","Serabelisib (TAK-117)","d4","L3800-35","in 10mM DMSO","N/A","N/A","Phase 2","PI3K","PI3K/Akt/mTOR","Serabelisib (TAK-117, INK-1117, MLN-1117) is a potent and selective oral PI3Kα isoform inhibitor (IC50 of 21 nmol/L against PI3Kα) that has demonstrated > 100-fold selectivity relative to other class I PI3K family members (PI3Kβ/γ/δ) and mTOR, and a high degree of selectivity against many other kinase.",363.37,"1268454-23-4",{"v":16,"d":"16.00"},44.03,"<1","N/A","http://selleckchem.com/products/tak-117-ink-1117-mln-1117.html","C19H17N5O3","free base","INK-1117, MLN-1117","NC1=NC2=C(O1)C=CC(=C2)C3=C[N]4C(=NC=C4C(=O)N5CCOCC5)C=C3",0.939,5,1,2]
["S8594","Tirofiban Hydrochloride","g4","L3800-35","in 10mM DMSO","FDA,DMF,HMA","Martindale:The Extra Pharmacopoeia","Marketed","Integrin","Cytoskeletal Signaling","Tirofiban Hydrochloride (MK-383) is the hydrochloride salt form of tirofiban, a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation. It is more soluable than Tirofiban.",495.07,"150915-40-5",{"v":95,"d":"95.00"},191.89,{"v":95,"d":"95.00"},191.89,"http://selleckchem.com/products/tirofiban-hydrochlorid.html","C22H36N2O5S.HCl.H2O","hydrochloride hydrate","MK-383 Hydrochloride","O.Cl.CCCC[S](=O)(=O)NC(CC1=CC=C(OCCCCC2CCNCC2)C=C1)C(O)=O",0.922,4,2,14]
["S8598","S 38093","h4","L3800-35","in 10mM DMSO","N/A","N/A","Phase 2","Histamine Receptor","Neuronal Signaling","S 38093 is a histamine H3 antagonist/inverse agonist with a moderate affinity for rat, mouse and human H3 receptors (Ki = 8.8, 1.44 and 1.2 μM, respectively) and no affinity for other histaminergic receptors.",288.38,"862896-30-8",{"v":57,"d":"57.00"},197.66,"<1","N/A","http://selleckchem.com/products/S-38093.html","C17H24N2O2","free base","N/A","NC(=O)C1=CC=C(OCCCN2CC3CCCC3C2)C=C1",2.201,2,1,6]
["S8609","Derazantinib(ARQ-087)","c5","L3800-35","in 10mM DMSO","N/A","N/A","Phase 2","FGFR","Protein Tyrosine Kinase","Derazantinib(ARQ-087) is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with IC50 values of 1.8 nM for FGFR2, and 4.5 nM for FGFR1 and 3, showing lower potency for FGFR4 (IC50=34 nM). It also inhibits RET, DDR2, PDGFRβ, VEGFR and KIT.",468.57,"1234356-69-4",{"v":93,"d":"93.00"},198.48,"<1","N/A","http://www.selleckchem.com/products/derazantinib.html","C29H29FN4O","Free Base","N/A","COCCNCCC1=CC(=CC=C1)NC2=NC3=C(CC(C4=CC=CC=C4F)C5=C3C=CC=C5)C=N2",5.887,3,2,9]
["S8629","Linrodostat (BMS-986205)","f5","L3800-35","in 10mM DMSO","N/A","N/A","Phase 3","IDO/TDO","Metabolism","Linrodostat (BMS-986205, ONO-7701) is an irreversible inhibitor of IDO1 with an IC50 of 1.7 nM. It inhibits kynurenine production with IC50 values of 1.7, 1.1 and > 2000 in human HeLa, HEK293 expressing human IDO-1 and tryptophan-2, 3-dioxygenase cell-based assays.",410.91,"1923833-60-6",{"v":82,"d":"82.00"},199.56,"<1","N/A","https://www.selleckchem.com/products/bms-986205.html","C24H24ClFN2O","free base","ONO-7701","CC(C1CCC(CC1)C2=CC=NC3=C2C=C(F)C=C3)C(=O)NC4=CC=C(Cl)C=C4",6.125,2,1,4]
["S8664","Pemrametostat (GSK3326595)","b6","L3800-35","in 10mM DMSO","N/A","N/A","Phase 2","Histone Methyltransferase,PRMT","Epigenetics","Pemrametostat (GSK3326595, EPZ015938) is an orally active, potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5) and potently inhibits tumor growth in vitro and in vivo in animal models.",452.55,"1616392-22-3",{"v":90,"d":"90.00"},198.87,"<1","N/A","http://selleckchem.com/products/gsk3326595-epz015938.html","C24H32N6O3","free base","EPZ015938","CC(=O)N1CCC(CC1)NC2=CC(=NC=N2)C(=O)NCC(O)CN3CCC4=C(C3)C=CC=C4",0.692,4,3,7]
["S8675","H3B-6527","d6","L3800-35","in 10mM DMSO","N/A","N/A","Phase 1","FGFR","Protein Tyrosine Kinase","H3B-6527 is a highly selective covalent FGFR4 inhibitor with an IC50 value of <1.2 nM and at least 250-fold selectivity over FGFR1-3 (IC50 values of 320, 1,290 and 1,060 nM respectively).",629.54,"1702259-66-2",{"v":50,"d":"50.00"},79.42,"<1","N/A","http://selleckchem.com/products/h3b-6527.html","C29H34Cl2N8O4","free base","N/A","CCN1CCN(CC1)C2=CC(=C(NC3=CC(=NC=N3)N(C)C(=O)NC4=C(Cl)C(=CC(=C4Cl)OC)OC)C=C2)NC(=O)C=C",{"v":5.16,"d":"5.160"},6,3,10]
["S8698","GLPG1837","h6","L3800-35","in 10mM DMSO","N/A","N/A","Phase 2","CFTR","Transmembrane Transporters","GLPG1837 (ABBV-974) is a novel CFTR potentiator with an EC50 value of 3 nM for F508del, showing enhanced efficacy on CFTR mutants harboring class III mutations compared to Ivacaftor.",348.42,"1654725-02-6",{"v":69,"d":"69.00"},198.04,"<1","N/A","http://selleckchem.com/products/glpg1837.html","C16H20N4O3S","free base","ABBV-974","CC1(C)CC2=C(SC(=C2C(N)=O)NC(=O)C3=N[NH]C=C3)C(C)(C)O1",1.611,4,3,3]
["S8711","Nemtabrutinib (ARQ 531)","c7","L3800-35","in 10mM DMSO","N/A","N/A","Phase 3","BTK","Angiogenesis","Nemtabrutinib (ARQ 531, MK-1026) is an ATP-competitive tyrosine kinase inhibitor designed to target BTK with an IC50 of 0.85 nM. It also has a distinct kinase selectivity profile with strong inhibitory activity against several key oncogenic drivers from TEC, Trk and Src family kinases.",478.93,"2095393-15-8",{"v":95,"d":"95.00"},198.36,"<1","N/A","https://www.selleckchem.com/products/arq531.html","C25H23ClN4O4","free base","MK-1026","OCC1CCC(CO1)NC2=C3C(=NC=N2)[NH]C=C3C(=O)C4=CC=C(OC5=CC=CC=C5)C=C4Cl",4.368,5,3,7]
["S8723","ABBV-744","f7","L3800-35","in 10mM DMSO","N/A","N/A","Phase 1","Epigenetic Reader Domain","Epigenetics","ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2, BRD3 and BRD4. It is developed for treating AML and cancers.",491.55,"2138861-99-9",{"v":98,"d":"98.00"},199.37,"<1","N/A","http://www.selleckchem.com/products/abbv-744.html","C28H30FN3O4","Free Base","N/A","CCNC(=O)C1=CC2=C([NH]1)C(=O)N(C)C=C2C3=C(OC4=C(C)C=C(F)C=C4C)C=CC(=C3)C(C)(C)O",{"v":4.36,"d":"4.360"},3,2,6]
["S8726","Anlotinib (AL3818) dihydrochloride","g7","L3800-35","in 10mM DMSO","CFDA","N/A","Marketed","VEGFR","Protein Tyrosine Kinase","Anlotinib (AL3818) is a highly potent and selective VEGFR2 inhibitor with IC50 less than 1 nM. It has broad-spectrum antitumor potential in clinical trials. Please use saline solution rather than PBS for dilutions. PBS may cause precipitation.",480.36,"1360460-82-7",{"v":96,"d":"96.00"},199.85,{"v":96,"d":"96.00"},199.85,"http://selleckchem.com/products/anlotinib-al3818.html","C23H22FN3O3.2HCl","dihydrochloride","N/A","Cl.Cl.COC1=C(OCC2(N)CC2)C=C3N=CC=C(OC4=C(F)C5=C([NH]C(=C5)C)C=C4)C3=C1",4.469,4,2,6]
["S8738","Bimiralisib (PQR309)","b8","L3800-35","in 10mM DMSO","N/A","N/A","Phase 2","mTOR,PI3K","PI3K/Akt/mTOR","Bimiralisib (PQR309) is a novel brain-penetrant dual PI3K/mTOR inhibitor with in vitro and in vivo antilymphoma activity. It displays excellent selectivity versus PI3K-related lipid kinases, protein kinases and unrelated targets.",411.38,"1225037-39-7",{"v":6,"d":"6.00"},14.59,"<1","N/A","http://www.selleckchem.com/products/pqr309-bimiralisib.html","C17H20F3N7O2","Free Base","N/A","NC1=NC=C(C2=NC(=NC(=N2)N3CCOCC3)N4CCOCC4)C(=C1)C(F)(F)F",1.891,6,1,4]
["S8749","MBQ-167","f8","L3800-35","in 10mM DMSO","N/A","N/A","Phase 1","Rho","Cell Cycle","MBQ-167 is a potent and dual inhibitor of Rac and Cdc42 with IC50s of 103 nM and 78 nM respectively, in metastatic breast cancer cells.",338.41,"2097938-73-1",{"v":68,"d":"68.00"},200.94,"<1","N/A","http://www.selleckchem.com/products/mbq-167.html","C22H18N4","Free Base","N/A","CC[N]1C2=C(C=CC=C2)C3=CC(=CC=C13)[N]4N=NC=C4C5=CC=CC=C5",5.446,2,0,3]
["S8754","Alofanib (RPT835)","a9","L3800-35","in 10mM DMSO","N/A","N/A","Phase 1","FGFR","Angiogenesis","Alofanib (RPT835) is a novel selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect with IC50 <10 nM on FGF2-induced phoshphorylation of FRS2a in KATO III cells. It has no direct effect on FGF2-dependent FGFR1 and FGFR3 phosphorylation levels in either cell lines and no effects on FGF2-FGFR2 binding.",{"v":413.4,"d":"413.40"},"1612888-66-0",{"v":83,"d":"83.00"},200.77,"<1","N/A","http://www.selleckchem.com/products/alofanib-rpt835.html","C19H15N3O6S","Free Base","N/A","CC1=CC(=C(N[S](=O)(=O)C2=CC=CC(=C2)C(O)=O)C=C1C3=CC=CN=C3)[N+]([O-])=O",2.695,4,1,6]
["S8760","Iberdomide (CC220)","d9","L3800-35","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,E3 Ligase ,E3 ligase Ligand,Immunology & Inflammation related","Immunology & Inflammation","Iberdomide (CC-220) is a novel oral immunomodulatory compound that targets cereblon, part of the CRL4CRBN E3 ubiquitin ligase complex, with an IC50 of 60 nM in a competitive TR-FRET assay. Iberdomide (CC-220) induces apoptosis with antitumor and immunostimulatory activities.",{"v":449.5,"d":"449.50"},"1323403-33-3",{"v":90,"d":"90.00"},200.22,"<1","N/A","http://www.selleck.cn/products/iberdomide.html","C25H27N3O5","free base","N/A","O=C1CCC(N2CC3=C(OCC4=CC=C(CN5CCOCC5)C=C4)C=CC=C3C2=O)C(=O)N1",{"v":1.56,"d":"1.560"},5,1,6]
["S8770","Lanifibranor (IVA-337)","h9","L3800-35","in 10mM DMSO","N/A","N/A","Phase 2","PPAR","Metabolism","Lanifibranor (IVA-337) is a moderately potent and well balanced pan PPAR agonist with EC50 values of 1537 nM, 866 nM and 206 nM for hPPARα, hPPARδ and hPPARγ, respectively.",434.92,"927961-18-0",{"v":87,"d":"87.00"},200.04,"<1","N/A","http://www.selleckchem.com/products/lanifibranor-iva-337.html","C19H15ClN2O4S2","Free Base","N/A","OC(=O)CCCC1=CC2=CC(=CC=C2[N]1[S](=O)(=O)C3=CC4=C(C=C3)N=CS4)Cl",4.676,4,0,6]
["S8791","Zanubrutinib (BGB-3111)","c10","L3800-35","in 10mM DMSO","N/A","N/A","Preregistration","BTK","Protein Tyrosine Kinase","Zanubrutinib (BGB-3111) is a potent, specific and irreversible BTK inhibitor that has been shown to have a lower off-target inhibitory activity on other kinases, including ITK, JAK3 and EGFR.",471.55,"1691249-45-2",{"v":94,"d":"94.00"},199.34,"<1","N/A","http://www.selleck.cn/products/zanubrutini-bgb-3111.html","C27H29N5O3","Free Base","N/A","NC(=O)C1=C2NCCC(C3CCN(CC3)C(=O)C=C)[N]2N=C1C4=CC=C(OC5=CC=CC=C5)C=C4",3.478,4,2,6]
["S8804","Brepocitinib (PF-06700841)","f10","L3800-35","in 10mM DMSO","N/A","N/A","Phase 2","JAK","JAK/STAT","Brepocitinib (PF-06700841, PF-841) is a potent inhibitor of Tyk2 and Jak1 with IC50s of 23 nM, 17 nM, 77 nM for Tyk2, Jak1 and Jak2 respectively. It has appropriate in-family selectivity against JAK2 and JAK3.",{"v":389.4,"d":"389.40"},"1883299-62-4",{"v":78,"d":"78.00"},200.31,"<1","N/A","http://www.selleck.cn/products/pf-06700841.html","C18H21F2N7O","Free Base","PF-841","C[N]1C=C(NC2=NC=CC(=N2)N3CC4CCC(C3)N4C(=O)C5CC5(F)F)C=N1",1.608,4,1,4]
["S8807","PFK158","g10","L3800-35","in 10mM DMSO","N/A","N/A","Phase 1","Autophagy,PFKFB","Cell Cycle","PFK158 is a potent and selective inhibitor of PFKFB3. It has improved PK properties and causes ~80% growth inhibition in several mouse models of human-derived tumors.",328.29,"1462249-75-7",{"v":14,"d":"14.00"},42.65,"<1","N/A","http://www.selleck.cn/products/pfk158.html","C18H11F3N2O","free base","N/A","FC(F)(F)C1=CC=C2C=CC(=NC2=C1)\\C=C\\C(=O)C3=CC=NC=C3",4.108,3,0,4]
["S8823","ABX-1431","b11","L3800-35","in 10mM DMSO","N/A","N/A","Phase 2","Lipase","Metabolism","ABX-1431 is a highly potent, selective, and CNS-penetrant Monoacylglycerol lipase (MGLL) inhibitor with IC50 values of 14 nM and 27 nM for hMGLL and mMGLL respectively.",507.39,"1446817-84-0",{"v":100,"d":"100.00"},197.09,"<1","N/A","http://www.selleck.cn/products/abx-1431.html","C20H22F9N3O2","Free Base","N/A","FC(F)(F)C(OC(=O)N1CCN(CC1)CC2=C(C=C(C=C2)C(F)(F)F)N3CCCC3)C(F)(F)F",5.372,2,0,8]
["S8867","Bentamapimod (AS602801)","f11","L3800-35","in 10mM DMSO","N/A","N/A","Phase 2","JNK","MAPK","Bentamapimod (AS602801) is a novel, orally active JNK inhibitor with IC50 values of 80 nM, 90 nM and 230 nM for JNK1, JNK2 and JNK3 respectively.",457.55,"848344-36-5",{"v":24,"d":"24.00"},52.45,"<1","N/A","http://www.selleck.cn/products/bentamapimod.html","C25H23N5O2S","free base","N/A","N#CC(C1=NC2=CC=CC=C2S1)C3=NC(=NC=C3)OCC4=CC=C(CN5CCOCC5)C=C4",4.228,5,0,7]
["S9001","Malic acid","a2","L3800-36","in 10mM DMSO","DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,IP2010","Phase 2/3","Others","Others","Malic acid (Hydroxybutanedioic acid, 2-Hydroxysuccinic acid) is a common, naturally occurring ingredient in many foods. It is the main acid found in apples and other fruits.",134.09,"6915-15-7",{"v":27,"d":"27.00"},201.36,"N/A","N/A","https://www.selleckchem.com/products/malic-acid.html","C4H6O5","free base","Hydroxybutanedioic acid, 2-Hydroxysuccinic acid","OC(CC(O)=O)C(O)=O",-1.012,2,1,3]
["S9007","2'-Deoxyguanosine monohydrate","d2","L3800-36","in 10mM DMSO","DMF","N/A","N/A","Others","Others","2'-Deoxyguanosine monohydrate is a kind of purine nucleoside.",267.24,"961-07-9",{"v":53,"d":"53.00"},198.32,"N/A","N/A","https://www.selleckchem.com/products/2-deoxyguanosine-monohydrate.html","C10H13N5O4","free base","2'-Deoxy-D-guanosine","NC1=NC2=C(N=C[N]2C3CC(O)C(CO)O3)C(=O)N1",-1.613,4,4,2]
["S9046","Berberine","h2","L3800-36","in 10mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,CP2005,KP Ⅹ,EP9.1,JP17,BP2017","N/A","Bacterial","Microbiology","Berberine (Umbellatine), an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic.",336.36,"2086-83-1",{"v":45,"d":"45.00"},133.78,"N/A","N/A","https://www.selleckchem.com/products/berberine.html","C20H18NO4","free base","Umbellatine","COC1=C(OC)C2=C(C=C1)C=C3C4=C(CC[N+]3=C2)C=C5OCOC5=C4",3.962,4,0,2]
["S9080","Anhydroicaritin","c3","L3800-36","in 10mM DMSO","N/A","N/A","Phase 4","Others","Apoptosis","Anhydroicaritin (Cycloicaritin), a prenylated flavonoid natural product, is commonly recognized as one of the effective compounds of Epimedii Herba and exhibits a variety of biological activities, such as activation of cancer cell apoptosis and inhibition of growth, protection against beta amyloid-induced neurotoxicity, and promotion of neuronal and cardiac cellular differentiation. It is a potent inhibitor of transcription factor SREBPs.",368.38,"118525-40-9",{"v":10,"d":"10.00"},27.15,"N/A","N/A","https://www.selleckchem.com/products/anhydroicaritin.html","C21H20O6","free base","Cycloicaritin","COC1=CC=C(C=C1)C2=C(O)C(=O)C3=C(O)C=C(O)C(=C3O2)CC=C(C)C",3.954,3,3,4]
["S9141","Berbamine","f3","L3800-36","in 10mM DMSO","CFDA","N/A","N/A","Apoptosis related,Bcr-Abl,CaMK,NF-κB","Angiogenesis","Berbamine (BA), a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan), is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF-κB. Berbamine (BA) induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca²⁺/calmodulin-dependent protein kinase II (CaMKII).",608.72,"478-61-5",{"v":100,"d":"100.00"},164.28,"N/A","N/A","https://www.selleckchem.com/products/berbamine.html","C37H40N2O6","free base","BA, BBM","COC1=C2OC3=C4C(CC5=CC=C(O)C(=C5)OC6=CC=C(CC7N(C)CCC(=C1)C7=C2)C=C6)N(C)CCC4=CC(=C3OC)OC",6.992,5,1,3]
["S9142","Sparteine","g3","L3800-36","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Sodium Channel","Transmembrane Transporters","Sparteine, which could be extracted from scotch broom, is a sodium channel blocker and a class 1a antiarrhythmic agent.",234.38,"492-08-0","N/A","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","https://www.selleckchem.com/products/sparteine.html","C15H26N2","free base","N/A","C1CCN2CC3CC(CN4CCCCC34)C2C1",2.363,0,0,0]
["S9193","Aristolochic acid A","c4","L3800-36","in 10mM DMSO","PMDA","JP17","N/A","AP-1,NF-κB","NF-κB","Aristolochic acid A (Aristolochic Acid I, Aristolochin, Aristolochine, TR 1736) is a carcinogenic, mutagenic, and nephrotoxic agent extracted from the flowering plant family Aristolochiaceae.Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and nuclear factor-κB (NF-κB) activities.",341.27,"313-67-7",{"v":6,"d":"6.00"},17.58,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/aristolochic-acid-a.html","C17H11NO7","Free Base","Aristolochic Acid I, Aristolochin, Aristolochine, TR 1736","COC1=CC=CC2=C3C4=C(OCO4)C=C(C(O)=O)C3=C(C=C12)[N+]([O-])=O",2.922,4,0,3]
["S9222","Dipotassium glycyrrhizinate","e4","L3800-36","in 10mM DMSO","NDC,PMDA","BP2017,CP2005","N/A","Immunology & Inflammation related","Immunology & Inflammation","Glycyrrhizinate dipotassium (Neubormitin) is a widely used anti-inflammatory agent isolated from the licorice root.",899.11,"68797-35-3",{"v":25,"d":"25.00"},27.81,"N/A","N/A","https://www.selleckchem.com/products/dipotassium-glycyrrhizinate.html","C42H60K2O16","free base","Neubormitin","[K+].[K+].CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(O)=O)OC6OC(C(O)C(O)C6OC7OC(C(O)C(O)C7O)C([O-])=O)C([O-])=O",-0.531,6,5,7]
["S9249","Securinine","h4","L3800-36","in 10mM DMSO","CFDA","N/A","N/A","GABA Receptor","Neuronal Signaling","Securinine, a major natural alkaloid product from the root of the plant Securinega suffruticosa, acts as a γ-amino butyric acid (GABA) receptor antagonist.",217.26,"5610-40-2",{"v":44,"d":"44.00"},202.52,"N/A","N/A","https://www.selleckchem.com/products/securinine.html","C13H15NO2","free base","N/A","O=C1OC23CC(C=CC2=C1)N4CCCCC34",1.449,2,0,0]
["S9311","Germacrone","c5","L3800-36","in 10mM DMSO","N/A","CP2005","N/A","Immunology & Inflammation related","Immunology & Inflammation","Germacrone, a major activity component found in Curcuma zedoaria oil product, shows anti-inflammatory, antiandrogenic, and antimicrobial activities.",218.33,"6902-91-6",{"v":44,"d":"44.00"},201.53,"N/A","N/A","https://www.selleckchem.com/products/germacrone.html","C15H22O","free base","N/A","CC(C)=C1C\\C=C(C)\\CC/C=C(C)/CC1=O",4.468,1,0,0]
["S9329","Orcinol","g5","L3800-36","in 10mM DMSO","N/A","BP2010","N/A","Others","Others","Orcinol (5-Methylresorcinol; 3,5-ToluenediolOrcin; 5-Methyl-1,3-benzenediol; 3,5-Dihydroxytoluene), occurs in many species of lichens including Roccella tinctoria and Lecanora, exhibits antimutagenic, antioxidant, antibacterial, radical-scavenging effects.",124.14,"504-15-4",{"v":24,"d":"24.00"},193.33,"N/A","N/A","https://www.selleckchem.com/products/orcinol.html","C7H8O2","free base","5-Methylresorcinol; 3,5-ToluenediolOrcin; 5-Methyl-1,3-benzenediol; 3,5-Dihydroxytoluene","CC1=CC(=CC(=C1)O)O",1.832,0,2,0]
["S9348","D-(+)-Trehalose Anhydrous","b6","L3800-36","in 10mM DMSO","N/A","N/A","Phase 3","Others","Others","Trehalose is a non-reducing sugar. It is thought to provide plants and animals with the ability to withstanding periods of dehydration.",{"v":342.3,"d":"342.30"},"99-20-7",{"v":68,"d":"68.00"},198.66,"N/A","N/A","https://www.selleckchem.com/products/d-trehalose-anhydrous.html","C12H22O11","free base","N/A","OCC1OC(OC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O",-4.261,3,8,4]
["S9349","D-(+)-Raffinose pentahydrate","c6","L3800-36","in 10mM DMSO","N/A","BP2019","N/A","Others","Others","Raffinose is a trisaccharide composed of galactose, glucose, and fructose.",594.51,"17629-30-0",{"v":100,"d":"100.00"},{"v":168.2,"d":"168.20"},"N/A","N/A","https://www.selleckchem.com/products/d-r-affinose-pentahydrate.html","C18H42O21","free base","N/A","O.O.O.O.O.OCC1OC(OCC2OC(OC3(CO)OC(CO)C(O)C3O)C(O)C(O)C2O)C(O)C(O)C1O",-7.094,5,11,8]
["S9368","ADP","f6","L3800-36","in 10mM DMSO","DMF","N/A","N/A","Others","Others","ADP (Adenosine diphosphate, adenosine pyrophosphate, Adenosine 5'-diphosphate) is an important organic compound in metabolism and is essential to the flow of energy in living cells.",{"v":427.2,"d":"427.20"},"58-64-0",{"v":6,"d":"6.00"},14.04,"N/A","N/A","https://www.selleckchem.com/products/adp.html","C10H15N5O10P2","free base","Adenosine diphosphate, adenosine pyrophosphate, Adenosine 5'-diphosphate","NC1=NC=NC2=C1N=C[N]2C3OC(CO[P](O)(=O)O[P](O)(O)=O)C(O)C3O",-2.239,6,3,6]
["S9382","Thymine","a7","L3800-36","in 10mM DMSO","N/A","BP2019;EP9.2;IP2010","N/A","DNA/RNA Synthesis","DNA Damage/DNA Repair","Thymine (5-methyluracil) is one of the four nucleobases in the nucleic acid of DNA.",126.11,"65-71-4",{"v":25,"d":"25.00"},198.23,"N/A","N/A","https://www.selleckchem.com/products/thymine.html","C5H6N2O2","free base","5-methyluracil","CC1=CNC(=O)NC1=O",-0.566,2,2,0]
["S9411","Liensinine","e7","L3800-36","in 10mM DMSO","N/A","N/A","Phase 2","Immunology & Inflammation related","Immunology & Inflammation","Liensinine, an important functional compound in lotus seeds, has anti-cancer, anti-fibrosis, anti-proliferative, antioxidant, and anti-inflammatory activities.",610.74,"2586-96-1",{"v":100,"d":"100.00"},163.74,"N/A","N/A","https://www.selleckchem.com/products/liensinine.html","C37H42N2O6","free base","N/A","COC1=CC2=C(C=C1OC)C(CC3=CC=C(O)C(=C3)OC4=CC5=C(CCN(C)C5CC6=CC=C(O)C=C6)C=C4OC)N(C)CC2",{"v":7.02,"d":"7.020"},4,2,9]
["S9449","Urocanic acid","h7","L3800-36","in 10mM DMSO","N/A","N/A","Phase 2","Others","Others","Urocanic acid is an intermediate in the catabolism of L-histidine.",138.12,"104-98-3",{"v":28,"d":"28.00"},202.72,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/urocanic-acid.html","C6H6N2O2","Free Base","N/A","OC(=O)/C=C/C1=C[NH]C=N1",0.243,2,1,2]
["S9454","Undecanoic acid","c8","L3800-36","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Others","Others","Undecanoic acid (Undecylic acid) is a medium chain length monocarboxylic acid that appears to be involved in the control of triacylglycerol synthesis.",186.29,"112-37-8","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/undecanoic-acid.html","C11H22O2","Free Base","Undecylic acid","CCCCCCCCCCC(O)=O",4.111,1,0,9]
["S9461","Benzonatate","h8","L3800-36","in 10mM DMSO","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37","N/A","Sodium Channel","Transmembrane Transporters","Benzonatate(Benzononatine)  has sodium channel-blocking properties and local anesthetic effects on the respiratory stretch receptors due to a tetracaine-like metabolite.",603.74,"32760-16-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","https://www.selleckchem.com/products/benzonatate.html","(C2H4O)nC12H17NO2","Free Base","Benzononatine","CCCCNC1=CC=C(C=C1)C(=O)OCCOC",3.426,3,1,9]
["S9467","Thiothixene","c9","L3800-36","in 10mM DMSO","FDA,DMF,NDC","USP42-NF37","N/A","Dopamine receptor & Adrenergic receptor","Neuronal Signaling","Thiothixene is an antipsychotic thioxanthene used for the management of schizophrenia. It has antagonistic effects on dopaminergic-receptor and alpha-adrenergic receptor.",443.63,"3313-26-6",{"v":5,"d":"5.00"},11.27,{"v":-1,"d":"-1.00"},"N/A","N/A","C23H29N3O2S2","Free Base","N/A","CN1CCN(CC\\C=C/2C3=C(SC4=C2C=C(C=C4)[S](=O)(=O)N(C)C)C=CC=C3)CC1",3.533,2,0,5]
["S9469","Haloperidol Decanoate","d9","L3800-36","in 10mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","Phase 3","D2R","Neuronal Signaling","Haloperidol Decanoate is an antipsychotic drug used for the management of schizophrenia. It has antagonistic effects on dopamine 2 receptor.",530.11,"74050-97-8",{"v":100,"d":"100.00"},188.64,{"v":-1,"d":"-1.00"},"N/A","N/A","C31H41ClFNO3","Decanoate","N/A","CCCCCCCCCC(=O)OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C3=CC=C(Cl)C=C3",8.127,3,0,16]
["S9500","Valbenazine tosylate","g9","L3800-36","in 10mM DMSO","FDA","N/A","Marketed","VMAT","Transmembrane Transporters","Valbenazine tosylate (NBI-98854) is the tosylate salt of valbenazine, a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no significant binding to VAMT1(Ki<10 μM).",762.97,"1639208-54-0",{"v":100,"d":"100.00"},131.07,{"v":-1,"d":"-1.00"},-1.31,"https://www.selleckchem.com/products/valbenazine-tosylate.html","C38H54N2O10S2","free base","NBI-98854","COC1=C(OC)C=C2C3CC(OC(=O)C(N)C(C)C)C(CC(C)C)CN3CCC2=C1.CC4=CC=C(C=C4)[S](O)(=O)=O.CC5=CC=C(C=C5)[S](O)(=O)=O",7.062,4,1,10]
["S9508","Brimonidine","b10","L3800-36","in 10mM DMSO","FDA,DMF,HMA,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","Marketed","Adrenergic Receptor","Neuronal Signaling","Brimonidine (Bromoxidine, UK 1430) is an alpha adrenergic receptor agonist (primarily alpha-2) and is used for the treatment of open-angle glaucoma or ocular hypertension to lower intraocular pressure.",292.13,"59803-98-4",{"v":26,"d":"26.00"},{"v":89,"d":"89.00"},{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/brimonidine.html","C11H10BrN5","Free Base","Bromoxidine, UK 14304","BrC1=C(NC2=NCCN2)C=CC3=C1N=CC=N3",1.237,3,2,2]
["S9560","Anisodamine Hydrobromide","f10","L3800-36","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","N/A","AChR,Adrenergic Receptor,Anti-infection,Immunology & Inflammation related","Immunology & Inflammation","Anisodamine (6-Hydroxyhyoscyamine) is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs).",386.28,"55449-49-5",{"v":77,"d":"77.00"},199.34,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/anisodamine-hydrobromide.html","C17H24BrNO4","Hydrobromide","6-Hydroxyhyoscyamine","Br.CN1C2CC(O)C1CC(C2)OC(=O)C(CO)C3=CC=CC=C3",1.121,2,2,5]
["S9568","Sapropterin Dihydrochloride","a11","L3800-36","in 10mM DMSO","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Hydroxylase","Metabolism","Sapropterin Dihydrochloride (Tetrahydrobiopterin, R-THBP), a synthetic preparation of the dihydrochloride salt of naturally occurring tetrahydrobiopterin (BH4), is a phenylalanine hydroxylase activator.",314.17,"69056-38-8",{"v":63,"d":"63.00"},200.53,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/sapropterin-dihydrochloride.html","C9H17Cl2N5O3","Dihydrochloride","Tetrahydrobiopterin Dihydrochloride, R-THBP Dihydrochloride","Cl.Cl.CC(O)C(O)C1CNC2=C(N1)C(=O)NC(=N2)N",-1.572,2,6,2]
["S5934","(-)-Fenchone","e11","L3800-36","in 10mM DMSO","N/A","Martindale the Extra Pharmacopoei,EP8.8,BP2020","N/A","Others","Others","Fenchone is a constituent of absinthe and the essential oil of fennel. It is used as a flavor in foods and in perfumery.",152.23,"7787-20-4","N/A","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","http://www.selleck.cn/products/fenchone.html","C10H16O","Free Base","N/A","CC1(C)C2CCC(C)(C2)C1=O",2.497,1,0,0]
["S6539","ASP5878","g11","L3800-36","in 10mM DMSO","N/A","N/A","Phase 1","FGFR","Protein Tyrosine Kinase","ASP5878 is a novel FGFR-selective inhibitor with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L for recombinant FGFR1, 2, 3, and 4, respectively.",407.37,"1453208-66-6",{"v":81,"d":"81.00"},198.84,"<1","N/A","http://www.selleck.cn/products/asp5878.html","C18H19F2N5O4","Free Base","N/A","COC1=C(F)C(=C(F)C(=C1)OC)COC2=CN=C(NC3=C[N](CCO)N=C3)N=C2",2.178,6,2,9]
["S6558","Irosustat (BN83495)","b2","L3800-37","in 10mM DMSO","N/A","N/A","Phase 2","Others","Metabolism","Irosustat (STX64, BN83495), a tricyclic coumarin sulfamate, is an orally active, nonsteroid-based, irreversible steroid sulfatase inhibitor with an IC50 of 8 nM.",309.34,"288628-05-7",{"v":62,"d":"62.00"},200.43,"<1","N/A","http://www.selleck.cn/products/irosustat.html","C14H15NO5S","Free Base","STX64","N[S](=O)(=O)OC1=CC=C2C3=C(CCCCC3)C(=O)OC2=C1",2.527,3,1,2]
["S6581","Fosamprenavir calcium salt","c2","L3800-37","in 10mM DMSO","FDA,DMF,NDC,PMDA","Martindale the Extra Pharmacopoei","Marketed","HIV Protease","Microbiology","Fosamprenavir(GW433908G) is a pro-drug of the protease inhibitor and antiretroviral drug amprenavir. It is used for the treatment of HIV-1 infections.",623.67,"226700-81-8",{"v":100,"d":"100.00"},160.34,"<1","N/A","http://www.selleck.cn/products/fosamprenavir-calcium-salt.html","C25H34CaN3O9PS","Calcium salt","GW433908G","[Ca++].CC(C)CN(CC(O[P]([O-])([O-])=O)C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)[S](=O)(=O)C3=CC=C(N)C=C3",{"v":0.18,"d":"0.180"},6,2,14]
["S6589","Norethisterone Enanthate","f2","L3800-37","in 10mM DMSO","CFDA,DMF","N/A","N/A","Others","Others","Norethisterone Enanthate (Norethindrone Enanthate) is a form of progestogen-only injectable birth control which is used to prevent pregnancy in women.",410.59,"3836-23-5",{"v":82,"d":"82.00"},199.71,"<1","N/A","http://www.selleck.cn/products/norethisterone-enanthate.html","C27H38O3","Free Base","Norethindrone Enanthate","CCCCCCC(=O)OC1(CCC2C3CCC4=CC(=O)CCC4C3CCC12C)C#C",7.186,3,0,7]
["S6617","MSX-122","a3","L3800-37","in 10mM DMSO","N/A","N/A","Phase 2","CXCR","Immunology & Inflammation","MSX-122 (Q-122) is a novel small molecule and partial CXCR4 antagonist (IC50~10 nM).",292.34,"897657-95-3",{"v":3,"d":"3.00"},10.26,"<1","N/A","http://www.selleck.cn/products/msx-122.html","C16H16N6","Free Base","Q-122","C(NC1=NC=CC=N1)C2=CC=C(CNC3=NC=CC=N3)C=C2",2.099,4,2,6]
["S6626","Brequinar (DUP785)","e3","L3800-37","in 10mM DMSO","N/A","Martindale the Extra Pharmacopoei","Phase 1/2","Dehydrogenase","Metabolism","Brequinar (DUP785, NSC 368390) is an inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of ∼20 nM in vitro.",375.37,"96187-53-0",{"v":37,"d":"37.00"},98.57,"<1","N/A","http://www.selleck.cn/products/brequinar.html","C23H15F2NO2","Free Base","NSC 368390","CC1=C(N=C2C=CC(=CC2=C1C(O)=O)F)C3=CC=C(C=C3)C4=C(F)C=CC=C4",6.008,2,0,3]
["S6631","Belotecan (CKD-602) hydrochloride","h3","L3800-37","in 10mM DMSO","marketed in Korea","N/A","Marketed","Topoisomerase","DNA Damage/DNA Repair","Belotecan (CKD-602) is a potent DNA topoisomerase I inhibitor that exerts a clinical anticancer effect on various types of tumor.",469.96,"213819-48-8",{"v":47,"d":"47.00"},100.01,{"v":4,"d":"4.00"},8.51,"http://www.selleck.cn/products/belotecan-ckd-602-hydrochloride.html","C25H28ClN3O4","Hydrochloride","N/A","Cl.CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC=CC5=C4CCNC(C)C)C2=O",2.713,4,1,5]
["S6646","Ciforadenant (CPI-444)","d4","L3800-37","in 10mM DMSO","N/A","N/A","Phase 1/2","Adenosine Receptor","GPCR & G Protein","Ciforadenant (CPI-444, V81444) is a potent and selective Adenosine A2A receptor antagonist. It binds to A2A receptors with a Ki of 3.54 nmol/L and demonstrates a greater than 50-fold selectivity for the A2A receptor over other adenosine receptor subtypes.",407.43,"1202402-40-1",{"v":81,"d":"81.00"},198.81,"<1","N/A","http://www.selleck.cn/products/cpi-444.html","C20H21N7O3","Free Base","V81444","CC1=CC=C(O1)C2=C3N=N[N](CC4=NC(=CC=C4)COC5CCOC5)C3=NC(=N2)N",1.769,8,1,6]
["S6726","MK1064","g4","L3800-37","in 10mM DMSO","N/A","N/A","Phase 1","OX Receptor","GPCR & G Protein","MK1064 is a selective orexin 2 receptor antagonist (2-SORA) with an IC50 of 18 nM.",{"v":461.9,"d":"461.90"},"1207253-08-4",{"v":92,"d":"92.00"},199.18,"<1","N/A","http://www.selleck.cn/products/mk1064.html","C24H20ClN5O3","Free Base","N/A","COC1=C(OC)N=C(CNC(=O)C2=CC(=CN=C2C3=NC=CC=C3)C4=CC(=CN=C4)Cl)C=C1",3.298,7,1,7]
["S6730","CC-401 Hydrochloride","b5","L3800-37","in 10mM DMSO","N/A","N/A","Phase 1","JNK","MAPK","CC-401 is a potent inhibitor of JNK with at least 40-fold selectivity against other related kinases.",424.93,"1438391-30-0",{"v":85,"d":"85.00"},200.03,{"v":85,"d":"85.00"},200.03,"http://www.selleck.cn/products/cc-401-hydrochloride.html","C22H25ClN6O","Hydrochloride","N/A","Cl.C1CCN(CC1)CCOC2=CC(=CC=C2)C3=N[NH]C4=CC=C(C=C34)C5=NC=N[NH]5",4.527,4,2,6]
["S6733","Edonerpic maleate","c5","L3800-37","in 10mM DMSO","N/A","N/A","Phase 2","Beta Amyloid","Neuronal Signaling","Edonerpic maleate (T-817) is a novel neurotrophic agent which can inhibit amyloid-β peptides (Aβ).",407.48,"519187-97-4",{"v":81,"d":"81.00"},198.78,{"v":81,"d":"81.00"},198.78,"http://www.selleck.cn/products/edonerpic-maleate.html","C20H25NO6S","Free Base","T-817 maleate","OC1CN(CCCOCCC2=CC3=C(SC=C3)C=C2)C1.OC(=O)\\C=C/C(O)=O",{"v":-0.67,"d":"-0.670"},3,1,9]
["S6746","APD668","f5","L3800-37","in 10mM DMSO","N/A","N/A","Phase 1","GPR","Endocrinology & Hormones","APD668 (JNJ28630368) is a potent GPR119 agonist with EC50s of 2.7 and 33 nM for human and rat forms, respectively.",477.51,"832714-46-2",{"v":96,"d":"96.00"},201.04,"<1","N/A","http://www.selleck.cn/products/apd668.html","C21H24FN5O5S","Free Base","JNJ28630368","CC(C)OC(=O)N1CCC(CC1)OC2=NC=NC3=C2C=N[N]3C4=CC=C(C=C4F)[S](C)(=O)=O",{"v":2.67,"d":"2.670"},8,0,6]
["S7716","Pimitespib (TAS-116)","a6","L3800-37","in 10mM DMSO","N/A","N/A","Phase 3","HSP (HSP90)","Cytoskeletal Signaling","Pimitespib (TAS-116) is a novel, small-molecule HSP90 inhibitor which inhibits geldanamycin-FITC binding to HSP90 proteins with Ki values of 34.7 nmol/L, 21.3 nmol/L, >50,000 nmol/L, and >50,000 nmol/L for HSP90α, HSP90β, GRP94, and TRAP1, respectively. Furthermore, TAS-116 does not inhibit other ATPases such as HSP70 (IC50 >200 μmol/L).",454.53,"1260533-36-5",{"v":91,"d":"91.00"},200.21,"<1","N/A","http://www.selleck.cn/products/tas-116.html","C25H26N8O","Free Base","N/A","CCC1=C(C=CC(=C1)C(N)=O)[N]2N=C(C(C)C)C3=C(C=CN=C23)[N]4C=NC(=C4)C5=C[N](C)N=C5",3.927,5,1,6]
["S8814","zipalertinib","e6","L3800-37","in 10mM DMSO","N/A","N/A","Phase 1/2","EGFR","Angiogenesis","TAS6417 (CLN-081, TPC-064) is a novel EGFR inhibitor that targets EGFR exon 20 insertion mutations while sparing wild-type (WT) EGFR. IC50 values ranges from 1.1 ± 0.1 to 8.0 ± 1.1 nmol/L.",396.44,"1661854-97-2",{"v":79,"d":"79.00"},199.27,"<1","N/A","http://www.selleck.cn/products/tas6417.html","C23H20N6O","Free Base","CLN-081, TPC-064,TAS6417","CC1=CC(C[N]2C3=NC=NC(=C3C(=C12)C4=CC5=CC=CC=C5N=C4)N)NC(=O)C=C",3.124,4,2,3]
["S8848","Futibatinib (TAS-120)","h6","L3800-37","in 10mM DMSO","N/A","N/A","Phase 2","FGFR","Protein Tyrosine Kinase","Futibatinib (TAS-120) is an irreversible fibroblast growth factor receptor (FGFR) inhibitor which inhibits all 4 subtypes of FGFR with enzyme IC50 values of 1.8 nM, 1.4 nM, 1.6 nM and 3.7 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.",418.45,"1448169-71-8",{"v":84,"d":"84.00"},200.74,"<1","N/A","http://www.selleck.cn/products/tas-120.html","C22H22N6O3","Free Base","N/A","COC1=CC(=CC(=C1)C#CC2=N[N](C3CCN(C3)C(=O)C=C)C4=NC=NC(=C24)N)OC",2.402,6,1,6]
["S8895","Ziritaxestat (GLPG1690)","d7","L3800-37","in 10mM DMSO","N/A","N/A","Phase 3","PDE","Metabolism","Ziritaxestat (GLPG1690) is a selective autotaxin inhibitor with an IC50 of 131 nM and Ki of 15 nM.",{"v":588.7,"d":"588.70"},"1628260-79-6",{"v":100,"d":"100.00"},169.87,"<1","N/A","http://www.selleck.cn/products/ziritaxestat.html","C30H33FN8O2S","Free Base","N/A","CCC1=C(N(C)C2=NC(=C(S2)C#N)C3=CC=C(F)C=C3)[N]4C=C(C=C(C)C4=N1)N5CCN(CC5)CC(=O)N6CC(O)C6",4.314,3,1,7]
["S9015","Homoharringtonine (CGX-635)","g7","L3800-37","in 10mM DMSO","DMF,CFDA","N/A","Marketed","STAT","JAK/STAT","Homoharringtonine (CGX-635, Omacetaxine mepesuccinate, HHT, Myelostat, NSC 141633), a plant alkaloid with antitumor properties, inhibits protein translation by preventing the initial elongation step of protein synthesis via an interaction with the ribosomal A-site. Homoharringtonine reversiblely inhibits IL-6-induced STAT3 Tyrosine 705 phosphorylation and reduced anti-apoptotic proteins expression.",545.62,"26833-87-4",{"v":10,"d":"10.00"},18.33,"N/A","N/A","https://www.selleckchem.com/products/homoharringtonine.html","C29H39NO9","free Base","Omacetaxine mepesuccinate, HHT, Myelostat, NSC 141633","COC(=O)CC(O)(CCCC(C)(C)O)C(=O)OC1C2C3=CC4=C(OCO4)C=C3CCN5CCCC25C=C1OC",2.418,7,0,11]
["S9028","Cimifugin","b8","L3800-37","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Others","Immunology & Inflammation","Cimifugin is a bioactive component of Saposhnikovia divaricata, a Chinese herb for treating allergy.",306.31,"37921-38-3",{"v":10,"d":"10.00"},32.65,"N/A","N/A","https://www.selleckchem.com/products/cimifugin.html","C16H18O6","free base","FC42575","COC1=C2CC(OC2=CC3=C1C(=O)C=C(CO)O3)C(C)(C)O",1.127,4,1,3]
["S9050","Boldine","c8","L3800-37","in 10mM DMSO","N/A","USP42-NF37;BP2019;EP9.7;Martindale:The Extra Pharmacopoeia","N/A","Adrenergic Receptor","Neuronal Signaling","Boldine, isolated from Peumus boldus, has alpha-adrenergic antagonist activities in vascular tissue with anti-oxidant, hepatoprotective, cytoprotective, antipyretic and anti-inflammatory effects.",327.37,"476-70-0",{"v":10,"d":"10.00"},30.55,"N/A","N/A","https://www.selleckchem.com/products/boldine.html","C19H21NO4","free base","1, 10-Dimethoxy-2, 9-dihydroxyaporphine; ex Peumus boldus","COC1=C(O)C=C2CC3N(C)CCC4=CC(=C(OC)C(=C34)C2=C1)O",3.083,2,2,2]
["S9102","Magnolin","f8","L3800-37","in 10mM DMSO","N/A","BP2019","N/A","ERK","MAPK","Magnolin is a natural compound abundantly found in Magnolia flos targeting ERK1 (IC50=87 nM) and ERK2 (IC50=16.5 nM) and inhibits cell transformation induced by tumor promoters such as epidermal growth factor (EGF).",416.46,"31008-18-1",{"v":83,"d":"83.00"},{"v":199.3,"d":"199.30"},"N/A","N/A","https://www.selleckchem.com/products/magnolin.html","C23H28O7","free Base","N/A","COC1=C(OC)C=C(C=C1)C2OCC3C2COC3C4=CC(=C(OC)C(=C4)OC)OC",2.618,7,0,7]
["S9171","Harpagoside","b9","L3800-37","in 10mM DMSO","N/A","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Immunology & Inflammation related","Immunology & Inflammation","Harpagoside, a natural product found in the plant Harpagophytum procumbens, has potent anti-rheumatic, anti-inflammatory and analgesic effects.",494.49,"19210-12-9",{"v":99,"d":"99.00"},200.21,"N/A","N/A","https://www.selleckchem.com/products/harpagoside.html","C24H30O11","free base","N/A","CC1(CC(O)C2(O)C=COC(OC3OC(CO)C(O)C(O)C3O)C12)OC(=O)\\C=C\\C4=CC=CC=C4",{"v":-1.39,"d":"-1.390"},5,5,7]
["S9192","Vitexin","d9","L3800-37","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Others","Others","Vitexin (Apigenin-8-C-glucoside), an naturally occuring apigenin flavone glycoside, acts as a platelet aggregation and alpha-glucosidase inhibitor and shows antineoplastic activity.",432.38,"3681-93-4",{"v":47,"d":"47.00"},{"v":108.7,"d":"108.70"},"N/A","N/A","https://www.selleckchem.com/products/vitexin.html","C21H20O10","free base","Apigenin-8-C-glucoside","OCC1OC(C(O)C(O)C1O)C2=C(O)C=C(O)C3=C2OC(=CC3=O)C4=CC=C(O)C=C4",0.018,3,7,3]
["S9248","Homoorientin","g9","L3800-37","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Immunology & Inflammation related","Immunology & Inflammation","Homoorientin (Isoorientin, Luteolin-6-C-glucoside) is a flavone that acts as a radical scavenger and an antineoplastic agent.",448.38,"4261-42-1",{"v":90,"d":"90.00"},200.72,"N/A","N/A","https://www.selleckchem.com/products/homoorientin.html","C21H20O11","free Base","Isoorientin, Luteolin-6-C-glucoside","OCC1OC(C(O)C(O)C1O)C2=C(O)C3=C(OC(=CC3=O)C4=CC(=C(O)C=C4)O)C=C2O",-0.224,3,8,3]
["S9288","Casticin","c10","L3800-37","in 10mM DMSO","N/A","BP2019;EP9.2","N/A","Immunology & Inflammation related","Immunology & Inflammation","Casticin (Vitexicarpin), as the major active substance in Lithospermum erythrorhyzon, had been reported to mediate multiple pharmacological activities such as antioxidation, antiviral, cardiovascular protection, antineoplastic and anti-inflammation.",374.34,"479-91-4",{"v":75,"d":"75.00"},200.35,"N/A","N/A","https://www.selleckchem.com/products/casticin.html","C19H18O8","free base","Vitexicarpin","COC1=C(O)C=C(C=C1)C2=C(OC)C(=O)C3=C(O2)C=C(OC)C(=C3O)OC",2.291,6,2,5]
["S9519","Fadrozole (CGS16949A)","f10","L3800-37","in 10mM DMSO","N/A","Martindale the Extra Pharmacopoei","Marketed","Aromatase","Endocrinology & Hormones","Fadrozole (CGS16949A) is a potent, selective, nonsteroidal inhibitor of aromatase with an IC50 of 4.5 nM and selectivity over other cytochrome P-450 enzymes.",223.27,"102676-47-1",{"v":45,"d":"45.00"},201.55,"<1","N/A","http://www.selleck.cn/products/fadrozole.html","C14H13N3","Free Base","CGS16949A","N#CC1=CC=C(C=C1)C2CCCC3=CN=C[N]23",2.271,1,0,1]
["S2100","Temocapril","a11","L3800-37","in 10mM DMSO","PMDA","JP17,Martindale the Extra Pharmacopoei","Marketed","ACE,RAAS","Endocrinology & Hormones","Temocapril (CS-622,temocaprilum) is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.",476.61,"111902-57-9",{"v":95,"d":"95.00"},199.32,"<1","N/A","http://www.selleck.cn/products/temocapril.html","C23H28N2O5S2","Free Base","CS-622,temocaprilum","CCOC(=O)C(CCC1=CC=CC=C1)NC2CSC(CN(CC(O)=O)C2=O)C3=CC=CS3",0.405,4,1,11]
["S2210","Sphingosine","b11","L3800-37","in 10mM DMSO","N/A","N/A","Phase 1","Others","Others","Sphingosine (2-amino-4-trans-octadecene-1,3-diol, C18 Sphingosine) is an 18-carbon amino alcohol with an unsaturated hydrocarbon chain, which forms a primary part of sphingolipids, a class of cell membrane lipids that include sphingomyelin, an important phospholipid.",299.49,"123-78-4",{"v":19,"d":"19.00"},63.44,"<1","N/A","http://www.selleck.cn/products/sphingosine.html","C18H37NO2","Free Base","2-amino-4-trans-octadecene-1,3-diol,C18 Sphingosine","CCCCCCCCCCCCC/C=C/C(O)C(N)CO",4.824,0,3,15]
["S2426","Tirapazamine","e11","L3800-37","in 10mM DMSO","N/A","Martindale the Extra Pharmacopoei","Phase 3","Others","Others","Tirapazamine (NSC 130181, SR 259075, SR 4233, Tirazone, WIN 59075) is a new anticancer drug in solid tumours. Tirapazamine exhibits preferential tumour cell killing and high specific toxicity to cells at low oxygen tensions.",178.15,"27314-97-2",{"v":36,"d":"36.00"},202.08,"<1","N/A","http://www.selleck.cn/products/tirapazamine.html","C7H6N4O2","Free Base","NSC 130181, SR 259075, SR 4233, Tirazone, WIN 59075","NC1=[N+]([O-])C2=CC=CC=C2[N+](=N1)[O-]",-0.565,1,1,0]
["S2488","VTP-27999 TFA","a2","L3800-38","in 10mM DMSO","N/A","N/A","Phase 1","RAAS","Endocrinology & Hormones","VTP-27999 TFA (VTP-27999 Trifluoroacetate, VTP-27999 2,2,2-trifluoroacetate) is an orally efficacious, selecitive alkyl amine renin inhibitor with IC50 of 0.47 nM for 0.3 nM of purified recombinant human renin.",{"v":639.1,"d":"639.10"},"1013937-63-7",{"v":100,"d":"100.00"},156.47,{"v":100,"d":"100.00"},156.47,"http://www.selleck.cn/products/vtp-27999-tfa.html","C28H42ClF3N4O7","TFA","VTP-27999 Trifluoroacetate, VTP-27999 2,2,2-trifluoroacetate","CNC(CNC(=O)N1CCCC(C1)C(OCCNC(=O)OC)C2=CC(=CC=C2)Cl)CC3CCCOC3.OC(=O)C(F)(F)F",0.798,6,3,13]
["S2935","Nicotinamide Riboside Chloride","d2","L3800-38","in 10mM DMSO","N/A","N/A","Phase 4","Sirtuin","DNA Damage/DNA Repair","Nicotinamide Riboside Chloride is the chloride salt form of nicotinamide riboside(NR).NR is a new form pyridine-nucleoside of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide(NAD) or NAD+ . Nicotinamide riboside chloride is a crystal form of Nicotinamide riboside (NR) chloride. Nicotinamide riboside chloride increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside chloride is used in dietary supplements.",{"v":290.7,"d":"290.70"},"23111-00-4",{"v":58,"d":"58.00"},199.52,{"v":58,"d":"58.00"},199.52,"http://www.selleck.cn/products/nicotinamide-riboside-chloride.html","C11H15ClN2O5","Chloride","N/A","[Cl-].NC(=O)C1=CC=C[N+](=C1)C2OC(CO)C(O)C2O",-3.882,2,4,3]
["S6657","2-Aminoethyl Diphenylborinate (2-APB)","g2","L3800-38","in 10mM DMSO","N/A","USP42-NF37","N/A","Calcium Channel,TRP Channel","Transmembrane Transporters","2-Aminoethyl Diphenylborinate (2-APB) is an IP3 receptor inhibitor and regulate IP3-induced calcium release.2-APB also inhibits the SOC channel activity and activates TRP channel at higher concentrations.",225.09,"524-95-8",{"v":45,"d":"45.00"},199.92,"<1","N/A","http://www.selleck.cn/products/2-aminoethyl-diphenylborinate.html","C14H16BNO","Free Base","N/A","NCCOB(C1=CC=CC=C1)C2=CC=CC=C2",3.656,1,1,5]
["S6665","Sparsentan (PS-433540, RE-021)","c3","L3800-38","in 10mM DMSO","N/A","N/A","Phase 3","Angiotensin Receptor,Endothelin Receptor","GPCR & G Protein","Sparsentan (PS-433540, RE-021, DARA) is a dual endothelin type A receptor(ETA) and angiotensin II type 1 receptor antagonist.",592.75,"254740-64-2",{"v":100,"d":"100.00"},168.71,"<1","N/A","http://www.selleck.cn/products/sparsentan.html","C32H40N4O5S","Free Base","DARA","CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C(=C3)COCC)C4=CC=CC=C4[S](=O)(=O)NC5=NOC(=C5C)C",5.728,7,1,12]
["S8882","ODM-203","f3","L3800-38","in 10mM DMSO","N/A","N/A","Phase 2","FGFR,VEGFR","Angiogenesis","ODM-203 is a selective inhibitor of FGFR and VEGFR with ic50s of 11 nM,16 nM,6 nM, 35 nM,26 nM,9 nM,5 nM for recombinant FGFR1, FGFR2, FGFR3,FGFR4, VEGFR1, VEGFR2 and VEGFR3, respectively.",505.54,"1430723-35-5",{"v":100,"d":"100.00"},197.81,"<1","N/A","http://www.selleck.cn/products/odm-203.html","C26H21F2N5O2S","Free Base","N/A","C[N]1C=C(C=N1)C2=CC3=C(C=C2)[N](C=N3)C4=CC(=CC(=C4)N[S](=O)(=O)C5CC5)C6=C(F)C=C(F)C=C6",4.626,4,1,6]
["S8893","Firsocostat (GS-0976)","g3","L3800-38","in 10mM DMSO","N/A","N/A","Phase 2","Acetyl-CoA carboxylase","Metabolism","Firsocostat (GS-0976, NDI-010976, ND-630) is a reversible inhibitor of acetyl CoA carboxylase (ACC)  with IC50s of 2.1 nM,6.1 nM for hACC1 and hACC2,respectively.",569.63,"1434635-54-7",{"v":100,"d":"100.00"},175.55,"<1","N/A","http://www.selleck.cn/products/nd-630.html","C28H31N3O8S","Free Base","NDI-010976, ND-630","COC1=CC=CC=C1C(CN2C(=O)N(C(=O)C3=C2SC(=C3C)C4=NC=CO4)C(C)(C)C(O)=O)OC5CCOCC5",2.946,8,0,9]
["S9131","Punicalagin","b4","L3800-38","in 10mM DMSO","N/A","N/A","Phase 4","Anti-infection,Immunology & Inflammation related","Immunology & Inflammation","Punicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects., Punicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects.",1084.72,"65995-63-3",{"v":100,"d":"100.00"},92.19,{"v":100,"d":"100.00"},92.19,"http://www.selleck.cn/products/punicalagin.html","C48H28O30","Free Base","N/A","OC1COC(=O)C2=CC(=C(O)C(=C2C3=C4C(=O)OC5=C(O)C(=C(C6=C5C4=C(OC6=O)C(=C3O)O)C7=C(C=C(O)C(=C7O)O)C(=O)OC1C8OC(=O)C9=CC(=C(O)C(=C9C%10=C(C=C(O)C(=C%10O)O)C(=O)OC8C=O)O)O)O)O)O",3.128,13,17,2]
["S0209","BVT 2733","e4","L3800-38","in 10mM DMSO","N/A","N/A","Phase 3","Dehydrogenase","Metabolism","BVT 2733, a new small molecule, is a non-steroidal, isoform-selective inhibitor of 11beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1).",428.96,"376640-41-4",{"v":86,"d":"86.00"},200.48,"˂1","N/A","http://www.selleckchem.com/products/bvt-2733.html","C17H21ClN4O3S2","Free Base","N/A","CN1CCN(CC1)C(=O)CC2=CSC(=N2)N[S](=O)(=O)C3=C(C)C(=CC=C3)Cl",{"v":2.3,"d":"2.300"},4,1,5]
["S0470","RSV604","a5","L3800-38","in 10mM DMSO","N/A","N/A","Phase 2","RSV","Microbiology","RSV604 (A-60444), a novel benzodiazepine, is an inhibitor of respiratory syncytial virus (RSV) with EC50 of 0.86 μM. RSV604 has significant potential for the effective treatment of RSV disease. Phase 2.",388.39,"676128-63-5",{"v":78,"d":"78.00"},200.83,"˂1","N/A","http://www.selleckchem.com/products/rsv604.html","C22H17FN4O2","Free Base","A-60444","FC1=CC=CC=C1NC(=O)NC2N=C(C3=CC=CC=C3)C4=CC=CC=C4NC2=O",3.689,3,3,3]
["S0523","SB 4","d5","L3800-38","in 10mM DMSO","N/A","N/A","Marketed","TGF-beta/Smad","TGF-beta/Smad","SB 4 is a potent and selective agonist of bone morphogenetic protein 4 (BMP4) signaling with EC50 of 74 nM. SB 4 enhances canonical BMP signaling and activates SMAD-1/5/9 phosphorylation.",{"v":320.2,"d":"320.20"},"100874-08-6",{"v":64,"d":"64.00"},199.88,"˂1","N/A","http://www.selleckchem.com/products/sb-4.html","C14H10BrNOS","Free Base","Benepali, Brenzys, Etanercept biosimilar","BrC1=CC=C(CSC2=NC3=CC=CC=C3O2)C=C1",4.771,2,0,3]
["S2447","Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222)","g5","L3800-38","in 10mM DMSO","DMF","N/A","N/A","ADC Cytotoxin,Microtubule Associated","Cytoskeletal Signaling","Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222, Antibiotic C 15003P3) is a potent inhibitor of tubulin polymerization with IC50 of 3.4 μM.",635.14,"66584-72-3",{"v":100,"d":"100.00"},157.45,"<1","N/A","http://www.selleckchem.com/products/ansamitocin-p-3-maytansinol-isobutyrate.html","C32H43ClN2O9","Free Base","Antibiotic C 15003P3","COC1\\C=C\\C=C(C)\\CC2=CC(=C(Cl)C(=C2)OC)N(C)C(=O)CC(OC(=O)C(C)C)C3(C)OC3C(C)C4CC1(O)NC(=O)O4",4.445,8,1,5]
["S6615","ATB 346","c6","L3800-38","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,COX,Others","Immunology & Inflammation","ATB 346, a novel hydrogen sulphide-releasing derivative of naproxen with remarkably reduced toxicity, inhibits COX activity. ATB 346 is an anti-inflammatory agent that induces apoptosis of human melanoma cells.",365.45,"1226895-20-0",{"v":73,"d":"73.00"},199.75,"<1","N/A","http://www.selleckchem.com/products/atb-346.html","C21H19NO3S","Free Base","N/A","COC1=CC2=CC=C(C=C2C=C1)C(C)C(=O)OC3=CC=C(C=C3)C(N)=S",4.521,3,1,6]
["S6782","Anle138b","f6","L3800-38","in 10mM DMSO","N/A","N/A","Phase 1","Others","Neuronal Signaling","Anle138b is a novel oligomer modulator and an aggregation inhibitor, blocking the formation of pathological aggregates of prion protein (PrP(Sc)) and of α-synuclein (α-syn) with good oral bioavailability, blood-brain-barrier penetration and no detectable toxicity. Anle138b shows a new approach for disease-modifying therapy in neurodegenerative diseases such as prion and Parkinson's disease.",343.17,"882697-00-9",{"v":69,"d":"69.00"},201.07,"<1","N/A","http://www.selleckchem.com/products/anle138b.html","C16H11BrN2O2","Free Base","N/A","BrC1=CC(=CC=C1)C2=CC(=N[NH]2)C3=CC=C4OCOC4=C3",4.547,3,1,2]
["S6813","Mobocertinib (TAK788)","g6","L3800-38","in 10mM DMSO","N/A","N/A","Phase 3","EGFR,HER2","Protein Tyrosine Kinase","Mobocertinib (TAK788, AP32788), an investigational TKI, is a potent, selective preclinical inhibitor of epidermal growth factor receptor (EGFR) and HER2 mutations. Mobocertinib (TAK788) is an antineoplastic agent.",{"v":585.7,"d":"585.70"},"1847461-43-1",{"v":9,"d":"9.00"},15.37,"<1","N/A","http://www.selleckchem.com/products/tak788.html","C32H39N7O4","Free Base","AP32788","COC1=C(NC2=NC=C(C(=O)OC(C)C)C(=N2)C3=C[N](C)C4=CC=CC=C34)C=C(NC(=O)C=C)C(=C1)N(C)CCN(C)C",5.252,6,2,13]
["S6829","Dithiothreitol (DTT)","a7","L3800-38","in 10mM DMSO","DMF","BP2017,USP43-NF38,EP9.2","N/A","Others","Others","Dithiothreitol (DTT, Cleland's reagent), a small-molecule redox reagent, is a standard agent for reducing disulfide bonds between and within biological molecules.",154.25,"3483-12-3",{"v":31,"d":"31.00"},200.97,{"v":31,"d":"31.00"},200.97,"http://www.selleckchem.com/products/dtt.html","C4H10O2S2","Free Base","Cleland's reagent","OC(CS)C(O)CS",0.023,0,2,3]
["S6844","Zatolmilast (BPN14770)","d7","L3800-38","in 10mM DMSO","N/A","N/A","Phase 2","PDE","Metabolism","Zatolmilast (BPN14770) is a selective allosteric inhibitor of phosphodiesterase 4D (PDE4D) with IC50 of 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3, respectively.",{"v":405.8,"d":"405.80"},"1606974-33-7",{"v":81,"d":"81.00"},199.61,"˂1","N/A","http://www.selleckchem.com/products/bpn14770.html","C21H15ClF3NO2","Free Base","N/A","OC(=O)CC1=CC=C(CC2=CC(=NC(=C2)C(F)(F)F)C3=CC=CC(=C3)Cl)C=C1",{"v":6.3,"d":"6.300"},2,0,6]
["S8953","ASP4132","h7","L3800-38","in 10mM DMSO","N/A","N/A","Phase 1","AMPK","PI3K/Akt/mTOR","ASP4132 is a potent and orally active activator of Adenosine Monophosphate-Activated Protein Kinase (AMPK) with EC50 of 0.018 μM. ASP4132 is used as a clinical candidate for the treatment of human cancer.",937.06,"1640294-30-9",{"v":100,"d":"100.00"},106.72,"<1","N/A","http://www.selleckchem.com/products/asp4132.html","C46H51F3N6O8S2","Free Base","N/A","COC1=NC=C(CN2CCC(CC2)C3=CC=C4[NH]C(=NC4=C3)C(=O)N5CCN(CC5)CC6=CC=C(C=C6)C(F)(F)F)C=C1.CC7=CC=C(C=C7)[S](O)(=O)=O.CC8=CC=C(C=C8)[S](O)(=O)=O",8.594,4,1,10]
["S8995","BAY 2416964","c8","L3800-38","in 10mM DMSO","N/A","N/A","Phase 1","AhR","Metabolism","BAY 2416964 (compound 192) is a potent and orally active antagonist of aryl hydrocarbon receptor (AhR) with IC50 of 341 nM. BAY 2416964 has the potential in the treatment of solid tumors.",387.82,"2242464-44-2",{"v":78,"d":"78.00"},201.12,"<1","N/A","http://www.selleckchem.com/products/bay-2416964.html","C18H18ClN5O3","Free Base","N/A","CC(CO)NC(=O)C1=CC(=NN(C1=O)C2=C[N](C)N=C2)C3=CC=C(Cl)C=C3",{"v":1.55,"d":"1.550"},4,2,5]
["S0076","ABX464","f8","L3800-38","in 10mM DMSO","N/A","N/A","Phase 2/3","HIV","Microbiology","ABX464 (SPL-464) is a novel anti-HIV molecule that inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) from 5 different donors with IC50 ranging between 0.1 μM and 0.5 μM.",338.71,"1258453-75-6",{"v":68,"d":"68.00"},200.76,"<1","N/A","http://www.selleckchem.com/products/abx464.html","C16H10ClF3N2O","free base","SPL-464","FC(F)(F)OC1=CC=C(NC2=NC3=C(C=CC=C3Cl)C=C2)C=C1",6.889,2,1,4]
["S0194","Balicatib","b9","L3800-38","in 10mM DMSO","N/A","N/A","Phase 2","Cysteine Protease","Proteases","Balicatib (AAE-581) is a potent and selective inhibitor of the osteoclastic enzyme cathepsin K.",411.54,"354813-19-7",{"v":82,"d":"82.00"},199.25,"<1","N/A","http://www.selleckchem.com/products/balicatib.html","C23H33N5O2","free base","AAE-581","CCCN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3(CCCCC3)C(=O)NCC#N",2.748,2,2,7]
["S0398","Astemizole","e9","L3800-38","in 10mM DMSO","DMF","Martindale:The Extra Pharmacopoeia, EP10.2, USP43-NF38","N/A","Histamine Receptor,Potassium Channel","Neuronal Signaling","Astemizole (R 43512) is a histamine H1-receptor antagonist with IC50 of 4.7 nM. Astemizole is also a potent inhibitor of ether à-go-go 1 (Eag1) and Eag-related gene (Erg) potassium channels. Astemizole has antineoplastic and antipruritic effects.",458.57,"68844-77-9",{"v":92,"d":"92.00"},200.62,"<1","N/A","http://www.selleckchem.com/products/astemizole.html","C28H31FN4O","free base","R 43512","COC1=CC=C(CCN2CCC(CC2)NC3=NC4=CC=CC=C4[N]3CC5=CC=C(F)C=C5)C=C1",5.689,2,1,8]
["S0444","Indibulin","f9","L3800-38","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,Microtubule Associated","Cytoskeletal Signaling","Indibulin (ZIO 301, D 24851, Zybulin) is an orally applied inhibitor of tubulin assembly with potent anticancer activity. Indibulin induces mitotic arrest and apoptosis.",389.83,"204205-90-3",{"v":40,"d":"40.00"},102.61,"<1","N/A","http://www.selleckchem.com/products/Indibulin.html","C22H16ClN3O2","free base","ZIO 301, D 24851, Zybulin","ClC1=CC=C(C[N]2C=C(C(=O)C(=O)NC3=CC=NC=C3)C4=CC=CC=C24)C=C1",4.097,3,1,5]
["S0555","Adomeglivant","a10","L3800-38","in 10mM DMSO","N/A","N/A","Phase 2","Glucagon Receptor","GPCR & G Protein","Adomeglivant (LY2409021) is a potent and selective antagonist of glucagon receptor that is used as a chronic treatment for type 2 diabetes.",555.63,"1488363-78-5",{"v":100,"d":"100.00"},179.98,"<1","N/A","http://www.selleckchem.com/products/ly2409021-adomeglivant.html","C32H36F3NO4","free base","LY2409021","CC1=C(C(=CC(=C1)OC(CCC(F)(F)F)C2=CC=C(C=C2)C(=O)NCCC(O)=O)C)C3=CC=C(C=C3)C(C)(C)C",7.839,3,1,12]
["S0785","Apilimod (STA-5326) mesylate","d10","L3800-38","in 10mM DMSO","N/A","N/A","Phase 2","Interleukins,PIKfyve","Immunology & Inflammation","Apilimod (STA-5326) mesylate is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases. Apilimod mesylate (STA-5326 mesylate) inhibits IL-12 with IC50 of 1 nM, 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs, human monocytes and mouse PBMCs, respectively. Apilimod mesylate (STA-5326 mesylate) is also a cell permeable small molecule that specifically inhibits PIKfyve with IC50 of 14 nM.",{"v":610.7,"d":"610.70"},"870087-36-8",{"v":60,"d":"60.00"},98.25,{"v":100,"d":"100.00"},163.75,"http://www.selleckchem.com/products/apilimod-mesylate.html","C25H34N6O8S2","mesylate","STA-5326 mesylate","CC1=CC(=CC=C1)/C=N/NC2=CC(=NC(=N2)OCCC3=CC=CC=N3)N4CCOCC4.C[S](O)(=O)=O.C[S](O)(=O)=O",3.657,6,1,8]
["S3217","Brilliant Blue G","h10","L3800-38","in 10mM DMSO","FDA, NDC","USP43-NF38","N/A","Dyes,P2 Receptor","Neuronal Signaling","Brilliant Blue G (BBG) is a potent non-competitive antagonist of P2X7 receptor with IC50 of 10.1 nM and 265 nM for rat P2X7 and human P2X7, respectively. Brilliant Blue G is a dye which is commonly used in laboratories to stain or quantify proteins.",854.02,"6104-58-1",{"v":100,"d":"100.00"},117.09,{"v":100,"d":"100.00"},117.09,"http://www.selleckchem.com/products/brilliant-blue-g.html","C47H48N3NaO7S2","free base","BBG","[Na+].CCOC1=CC=C(NC2=CC=C(C=C2)\\C(C3=CC=C(C=C3C)N(CC)CC4=CC=CC(=C4)[S]([O-])(=O)=O)=C/5C=CC(/C=C5C)=[N+](/CC)CC6=CC=CC(=C6)[S]([O-])(=O)=O)C=C1",5.617,1,1,15]
["S3273","Hypericin","c11","L3800-38","in 10mM DMSO","N/A","Martindale:The Extra Pharmacopoeia, EP10.2","N/A","Hydroxylase,MAO,P450 (e.g. CYP17),PKC,Reverse Transcriptase,Telomerase","Metabolism","Hypericin (Hyp, HY) is a naturally occurring substance found in the common St. John's Wort (Hypericum species) with antidepressive, antineoplastic and antiviral (human immunodeficiency and hepatitis C virus) activities. Hypericin has inhibitory effects on MAO (monoaminoxidase), PKC (protein kinase C), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450).",504.44,"548-04-9",{"v":100,"d":"100.00"},198.24,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/hypericin.html","C30H16O8","free base","Hyp, HY","CC1=C2C3=C(C)C=C(O)C4=C3C5=C6C2=C(C(=C1)O)C(=O)C7=C6C(=C(O)C=C7O)C8=C(O)C=C(O)C(=C58)C4=O",{"v":5.04,"d":"5.040"},2,6,0]
["S6664","Gefapixant","g11","L3800-38","in 10mM DMSO","N/A","N/A","Phase 3","P2 Receptor","Neuronal Signaling","Gefapixant (AF-219, MK-7264, R1646, RG-1646, RO 4926219) is an orally active small molecule antagonist of human P2X3 receptor with IC50 of about 30 nM, 100–250 nM for recombinant hP2X3 homotrimers and hP2X2/3 heterotrimeric receptors, respectively. Gefapixant has shown promise for the treatment of refractory and unexplained chronic cough.",{"v":353.4,"d":"353.40"},"1015787-98-0",{"v":71,"d":"71.00"},200.91,"<1","N/A","http://www.selleckchem.com/products/gefapixant.html","C14H19N5O4S","free base","AF-219, MK-7264, R1646,RG-1646,RO 4926219","COC1=CC(=C(OC2=CN=C(N)N=C2N)C=C1[S](N)(=O)=O)C(C)C",1.061,6,3,5]
["S6852","Gossypol","b2","L3800-39","in 10mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","N/A","Apoptosis related,Bcl-2,Dehydrogenase","Apoptosis","Gossypol (BL 193) is an orally-active polyphenol isolated from cotton seeds and roots. Gossypol is a potent inhibitor of 5α-reductase 1 and 3α-hydroxysteroid dehydrogenase with IC50 of 3.33 μM and 0.52 μM in cell-free assay, respectively. Gossypol also inhibits the binding of BH3 peptide to Bcl protein with IC50 of 0.4 μM and 10 μM for Bcl-XL and Bcl-2, respectively. Gossypol induces apoptosis and cell growth inhibition in various cancer cells.",518.55,"303-45-7",{"v":100,"d":"100.00"},192.85,"<1","N/A","http://www.selleckchem.com/products/gossypol.html","C30H30O8","free base","BL 193","CC(C)C1=C(O)C(=C(C=O)C2=C1C=C(C)C(=C2O)C3=C(O)C4=C(C=C3C)C(=C(O)C(=C4C=O)O)C(C)C)O",6.592,2,6,5]
["S6870","Ningetinib","e2","L3800-39","in 10mM DMSO","N/A","N/A","Phase 2","Axl,c-Met,VEGFR","Protein Tyrosine Kinase","Ningetinib (CT-053, DE-120, CT053PTSA) is a potent, orally bioavailable inhibitor of tyrosine kinase with IC50 of 6.7 nM, 1.9 nM and <1.0 nM for c-Met, VEGFR2 and Axl, respectively. Ningetinib exhibits antitumor activity.",556.58,"1394820-69-9",{"v":20,"d":"20.00"},35.93,"<1","N/A","http://www.selleckchem.com/products/ningetinib.html","C31H29FN4O5","free base","CT-053, DE-120, CT053PTSA","CN1N(C(=O)C(=C1C)C(=O)NC2=CC(=C(OC3=C4C=CC(=CC4=NC=C3)OCC(C)(C)O)C=C2)F)C5=CC=CC=C5",3.942,5,1,8]
["S6889","Monomethyl Fumarate","f2","L3800-39","in 10mM DMSO","FDA, DMF, NDC","N/A","N/A","Apoptosis related,Autophagy,GPR","GPCR & G Protein","Monomethyl Fumarate (MMF, Monomethylfumarate, Fumaric acid monomethyl ester, Methyl hydrogen fumarate), the active metabolite of the psoriasis drug Fumaderm, is a potent GPR109A agonist. Monomethyl Fumarate prevents major dysfunctions associated with neurodegenerative diseases: oxidative stress, mitochondrial dysfunction, apoptosis and autophagy.",{"v":130.1,"d":"130.10"},"2756-87-8",{"v":26,"d":"26.00"},199.85,{"v":20,"d":"20.00"},153.73,"http://www.selleckchem.com/products/monomethyl-fumarate.html","C5H6O4","free base","MMF, Monomethylfumarate, Fumaric acid monomethyl ester, Methyl hydrogen fumarate","COC(=O)\\C=C\\C(O)=O",0.264,3,0,3]
["S6910","Preladenant","a3","L3800-39","in 10mM DMSO","N/A","N/A","Phase 3","Adenosine Receptor","GPCR & G Protein","Preladenant (Privadenant, SCH 420814, MK-3814) is a potent, competitive and selective antagonist of the human adenosine A2A receptor with Ki of 1.1 nM.",503.56,"377727-87-2",{"v":8,"d":"8.00"},15.89,"<1","N/A","http://www.selleckchem.com/products/preladenant.html","C25H29N9O3","free base","Privadenant, SCH 420814, MK-3814","COCCOC1=CC=C(C=C1)N2CCN(CC2)CC[N]3N=CC4=C3N=C(N)[N]5N=C(N=C45)C6=CC=CO6",2.456,7,1,9]
["S8845","GSK3145095","d3","L3800-39","in 10mM DMSO","N/A","N/A","Phase 2","RIP kinase","Apoptosis","GSK3145095 is a potent and orally active RIP1 kinase inhibitor with IC50 of 6.3 nM with potential antineoplastic and immunomodulatory activities.",397.38,"1622849-43-7",{"v":79,"d":"79.00"},{"v":198.8,"d":"198.80"},"<1","N/A","http://www.selleckchem.com/products/gsk3145095.html","C20H17F2N5O2","free base","N/A","FC1=CC2=C(NC(=O)C(CC2)NC(=O)C3=N[NH]C(=N3)CC4=CC=CC=C4)C(=C1)F",2.573,4,3,4]
["S9602","Elraglusib","h3","L3800-39","in 10mM DMSO","N/A","N/A","Phase 2","Apoptosis related,GSK-3","PI3K/Akt/mTOR","Elraglusib(9-ING-41) is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with antitumor activity. 9-ING-41 induces apoptosis and cell cycle arrest at prophase by targeting centrosomes and microtubule-bound GSK3β.",404.35,"1034895-42-5",{"v":81,"d":"81.00"},200.32,"<1","N/A","http://www.selleckchem.com/products/9-ing-41.html","C22H13FN2O5","free base","9-ing-41","C[N]1C=C(C2=CC3=C(OCO3)C=C12)C4=C(C(=O)NC4=O)C5=COC6=C5C=C(F)C=C6",3.339,5,1,2]
["S9621","Donafenib (Sorafenib D3)","b4","L3800-39","in 10mM DMSO","N/A","N/A","Phase 3","Raf,VEGFR","MAPK","Donafenib (Sorafenib D3, Bay 43-9006 D3, CM-4307) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 15 nM, 20 nM and 22 nM for Raf-1, mVEGFR-2, mVEGFR-3 and B-RAF, respectively.",467.84,"1130115-44-4",{"v":94,"d":"94.00"},200.92,"<1","N/A","http://www.selleckchem.com/products/donafenib-sorafenib-d3.html","C21H13D3ClF3N4O3","free base","Bay 43-9006 D3, CM-4307","C(NC(=O)C1=NC=CC(=C1)OC2=CC=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2)([2H])([2H])[2H]",4.175,4,3,7]
["S9649","Acelarin (NUC-1031)","f4","L3800-39","in 10mM DMSO","N/A","N/A","Phase 3","DNA/RNA Synthesis","DNA Damage/DNA Repair","Acelarin (NUC-1031, CPF-31, MTL-007, GTPL7389) is a DNA synthesis inhibitor with EC50 of 0.2 nM.",580.47,"840506-29-8",{"v":100,"d":"100.00"},172.27,"<1","N/A","http://www.selleckchem.com/products/acelarin-nuc-1031.html","C25H27F2N4O8P","free base","CPF-31, MTL-007, GTPL7389","CC(N[P](=O)(OCC1OC(N2C=CC(=NC2=O)N)C(F)(F)C1O)OC3=CC=CC=C3)C(=O)OCC4=CC=CC=C4",{"v":1.69,"d":"1.690"},7,3,12]
["S0165","Ampalex (CX-516)","a5","L3800-39","in 10mM DMSO","DMF","N/A","N/A","GluR","Neuronal Signaling","Ampalex (CX-516, Ampakine CX 516, BDP-12, SPD 420) is a positive allosteric modulator of AMPA receptor. Ampalex exhibits potential treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI).",241.29,"154235-83-3",{"v":48,"d":"48.00"},198.93,{"v":48,"d":"48.00"},198.93,"https://www.selleckchem.com/products/cx-516.html","C14H15N3O","Free Base","Ampakine CX 516, BDP-12, SPD 420","O=C(N1CCCCC1)C2=CC3=NC=CN=C3C=C2",1.625,3,0,1]
["S0323","Antineoplaston A10","d5","L3800-39","in 10mM DMSO","DMF","N/A","N/A","Ras","Apoptosis","Antineoplaston A10 is a naturally occurring substance in the human body that that can be potentially used for the treatment of glioma, lymphoma, astrocytoma and breast cancer. The main ingredient active of antineoplaston A10 (Phenylacetylglutamine, PG) inhibits RAS and promotes apoptosis.",246.26,"91531-30-5",{"v":49,"d":"49.00"},198.98,"<1","N/A","https://www.selleckchem.com/products/antineoplaston-a10.html","C13H14N2O3","Free Base","N/A","O=C1CCC(NC(=O)CC2=CC=CC=C2)C(=O)N1",0.307,3,2,3]
["S0467","Emodepside","e5","L3800-39","in 10mM DMSO","N/A","N/A","Phase 2","Parasite,Potassium Channel","Immunology & Inflammation","Emodepside (QHT06, BAY 44-4400, PF 1022-221), a semisynthetic derivative of PF1022A, is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity. Emodepside activates Ca-dependent SLO-1-like K channels.",1119.39,"155030-63-0",{"v":100,"d":"100.00"},89.33,"<1","N/A","https://www.selleckchem.com/products/qht06.html","C60H90N6O14","Free Base","QHT06, BAY 44-4400, PF 1022-221","CC(C)CC1N(C)C(=O)C(C)OC(=O)C(CC(C)C)N(C)C(=O)C(CC2=CC=C(C=C2)N3CCOCC3)OC(=O)C(CC(C)C)N(C)C(=O)C(C)OC(=O)C(CC(C)C)N(C)C(=O)C(CC4=CC=C(C=C4)N5CCOCC5)OC1=O",7.503,14,0,14]
["S0496","PF-04995274","h5","L3800-39","in 10mM DMSO","N/A","N/A","Phase 1","5-HT Receptor","Neuronal Signaling","PF-04995274 (PF-4995274) is a potent, high-affinity, orally active and partial agonist of serotonin 4 receptor (5-HT4R) with EC50 of 0.47 nM, 0.36 nM, 0.37 nM and 0.26 nM for human 5-HT4A/4B/4D/4E, respectively. As for rat 5-HT4S/4L/4E, the EC50 is 0.59 nM, 0.65 nM and 0.62 nM, respectively. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease.",432.51,"1331782-27-4",{"v":86,"d":"86.00"},198.84,"<1","N/A","https://www.selleckchem.com/products/pf-04995274.html","C23H32N2O6","Free Base","PF-4995274","OC1(CCOCC1)CN2CCC(CC2)COC3=NOC4=C3C(=CC=C4)OC5CCOC5",1.615,6,0,7]
["S0552","BNC210","c6","L3800-39","in 10mM DMSO","N/A","N/A","Phase 2","AChR","Neuronal Signaling","BNC210 (H-Ile-Trp-OH, IW-2143) is a negative allosteric modulator of alpha-7 nicotinic acetylcholine receptor (α7 nAChR).",317.38,"13589-06-5",{"v":63,"d":"63.00"},{"v":198.5,"d":"198.50"},"<1","N/A","https://www.selleckchem.com/products/bnc210.html","C17H23N3O3","Free Base","H-Ile-Trp-OH, IW-2143","CCC(C)C(N)C(=O)NC(CC1=C[NH]C2=CC=CC=C12)C(O)=O",-0.469,2,3,7]
["S0869","Carbetapentane","g6","L3800-39","in 10mM DMSO","DMF, CFDA, PMDA","KP Ⅹ, JP17","N/A","Sigma Receptor","GPCR & G Protein","Carbetapentane (Pentoxyverine, CB) is an antitussive anticonvulsant nonselective sigma-1 (σ1) agonist.",333.46,"77-23-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","https://www.selleckchem.com/products/carbetapentane.html","C20H31NO3","Free Base","Pentoxyverine, CB","CCN(CC)CCOCCOC(=O)C1(CCCC1)C2=CC=CC=C2",3.845,3,0,11]
["S1272","XL228","b7","L3800-39","in 10mM DMSO","N/A","N/A","Phase 1","Aurora Kinase,Bcr-Abl,IGF-1R,Src","Angiogenesis","XL228 is a protein kinase inhibitor with IC50 of 5 nM, 1.4 nM, 3.1 nM, 1.6 nM, 6.1 nM and 2 nM for wild-type ABL kinase, ABL T315I, Aurora A, IGF-1R, SRC and LYN, respectively.",437.54,"898280-07-4",{"v":88,"d":"88.00"},201.12,"<1","N/A","https://www.selleckchem.com/products/xl228.html","C22H31N9O","Free Base","N/A","CC(C)C1=NOC(=C1)CNC2=NC(=CC(=N2)N3CCN(C)CC3)NC4=N[NH]C(=C4)C5CC5",4.542,5,3,8]
["S2962","NP-G2-044","f7","L3800-39","in 10mM DMSO","N/A","N/A","Phase 2","Fascin","Stem Cells & Wnt","NP-G2-044 is a potent, orally active inhibitor of the actin-bundling activity of fascin with IC50 of ~0.2 μM. NP-G2-044 blocks tumor metastasis and increases antitumor immune response.",399.37,"1807454-59-6",{"v":80,"d":"80.00"},200.32,"<1","N/A","https://www.selleckchem.com/products/np-g2-044.html","C21H16F3N3O2","Free Base","N/A","CC1=C(C=CO1)C(=O)NC2=N[N](CC3=CC=C(C=C3)C(F)(F)F)C4=CC=CC=C24",4.778,3,1,5]
["S3029","Malonic acid","a8","L3800-39","in 10mM DMSO","N/A","USP43-NF38","N/A","Others","Others","Malonic acid (MOA), one of the major dicarboxylic acids (DCAs) in aerosols, has been identified experimentally and computationally to be a strong acid. Malonic acid (MOA) acts as a mediate bridge for the formation of pure SA-A-based clusters.",104.06,"141-82-2",{"v":20,"d":"20.00"},{"v":192.2,"d":"192.20"},{"v":20,"d":"20.00"},{"v":192.2,"d":"192.20"},"https://www.selleckchem.com/products/malonic-acid.html","C3H4O4","Free Base","MOA","OC(=O)CC(O)=O",-0.394,2,0,2]
["S3093","Pyrazole","d8","L3800-39","in 10mM DMSO","DMF","USP43-NF38","N/A","Others","Others","Pyrazole (1H-pyrazole) is a five membered heteroaromatic ring with two nitrogen atoms is of immense significance. Pyrazole is an indispensable anchor for design and development of new pharmacological agents.",68.08,"288-13-1",{"v":14,"d":"14.00"},205.64,{"v":14,"d":"14.00"},205.64,"https://www.selleckchem.com/products/pyrazole.html","C3H4N2","Free Base","1H-pyrazole","[NH]1C=CC=N1",0.273,1,1,0]
["S3101","2-Deoxy-D-ribose","e8","L3800-39","in 10mM DMSO","N/A","EP10.4","N/A","Others","Others","2-Deoxy-D-ribose (Thyminose, Deoxyribose) is an endogenous metabolite.",134.13,"533-67-5",{"v":27,"d":"27.00"},{"v":201.3,"d":"201.30"},{"v":27,"d":"27.00"},{"v":201.3,"d":"201.30"},"https://www.selleckchem.com/products/2-deoxy-d-ribose.html","C5H10O4","Free Base","Thyminose, Deoxyribose","OCC(O)C(O)CC=O",-1.628,1,3,4]
["S3134","D-(-)-Tartaric acid","h8","L3800-39","in 10mM DMSO","DMF,CFDA,FDA,PMDA","USP40-NF35,IP2010,JP16","N/A","Others","Others","D-(-)-Tartaric acid is the unnatural isomer of Tartaric acid which is an important chiral chemical building block with broad industrial and scientific applications.",150.09,"147-71-7",{"v":30,"d":"30.00"},199.88,{"v":30,"d":"30.00"},199.88,"https://www.selleckchem.com/products/d-tartaric-acid.html","C4H6O6","Free Base","D-Tartaric acid","OC(C(O)C(O)=O)C(O)=O",-1.664,2,2,3]
["S3218","Amiloxate","d9","L3800-39","in 10mM DMSO","N/A","USP43-NF38","N/A","Anti-infection","Microbiology","Amiloxate (Amiloxiate, Isoamyl Methoxycinnamate, Isopentyl 4-methoxycinnamate, Isoamyl 4-methoxycinnamate, Isoamyl p-methoxycinnamate, Isopentyl p-methoxycinnamate) is EMA-approved chemical UV-filter used in cosmetics. Amiloxate is a cinnamic acid derivative with anti-inflammatory activity.",248.32,"71617-10-2","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","https://www.selleckchem.com/products/amiloxate.html","C15H20O3","Free Base","Amiloxiate, Isoamyl Methoxycinnamate, Isopentyl 4-methoxycinnamate, Isoamyl 4-methoxycinnamate, Isoamyl p-methoxycinnamate, Isopentyl p-methoxycinnamate","COC1=CC=C(C=CC(=O)OCCC(C)C)C=C1",3.717,3,0,7]
["S3332","D-Mannosamine hydrochloride","g9","L3800-39","in 10mM DMSO","DMF","N/A","N/A","Others","Others","D-Mannosamine hydrochloride ((2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride) is an active endogenous metabolite.",215.63,"5505-63-5",{"v":43,"d":"43.00"},199.42,{"v":43,"d":"43.00"},199.42,"https://www.selleckchem.com/products/d-mannosamine-hydrochloride.html","C6H14ClNO5","Hydrochloride","(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride","Cl.NC(C=O)C(O)C(O)C(O)CO",-2.699,1,5,5]
["S3371","N-Acetyl-D-mannosamine","b10","L3800-39","in 10mM DMSO","DMF","N/A","N/A","Others","Others","N-Acetyl-D-mannosamine (ManNAc, N-acetyl-beta-mannosamine), a precursor of a sialic acid, improves the age-dependent attenuation of synaptic transmission and long-term potentiation (LTP). N-Acetyl-D-mannosamine treatment is a potential therapeutic application for cognitive dysfunction.",221.21,"7772-94-3",{"v":44,"d":"44.00"},198.91,{"v":44,"d":"44.00"},198.91,"https://www.selleckchem.com/products/n-acetyl-d-mannosamine.html","C8H15NO6","Free Base","ManNAc, N-acetyl-beta-mannosamine","CC(=O)NC1C(O)OC(CO)C(O)C1O",-2.782,2,4,2]
["S5645","Hemin","f10","L3800-39","in 10mM DMSO","DMF, PMDA","N/A","N/A","Heme Oxygenase","Apoptosis","Hemin (protohemin) is an iron-containing porphyrin used in the management of porphyria attacks, particularly in acute intermittent porphyria.Hemin is an Heme oxygenase (HO)-1 inducer.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!",651.94,"16009-13-5",{"v":20,"d":"20.00"},30.68,"<1","N/A","https://www.selleckchem.com/products/hemin.html","C34H32ClFeN4O4","Free Base","protohemin","CC1=C(CCC(O)=O)C\\2=N\\C1=C/C3=C(C=C)C(=C4\\C=C5/N=C(/C=C6\\N([Fe](Cl)[N]34)\\C(=C2)C(=C6C)CCC(O)=O)C(=C5C=C)C)C",6.404,4,0,8]
["S6890","Trypan Blue","a11","L3800-39","in 10mM DMSO","FDA, DMF, NDC","USP43-NF38","N/A","Dyes","Others","Trypan Blue (Visionblue, Diphenyl Blue, Direct Blue 14) is a colorimetric dye that stains dead cells with a blue color easily observed using light microscopy at low resolution.",960.81,"72-57-1",{"v":100,"d":"100.00"},104.08,{"v":100,"d":"100.00"},104.08,"https://www.selleckchem.com/products/trypan-blue.html","C34H24N6Na4O14S4","Free Base","Visionblue, Diphenyl Blue, Direct Blue 14","[Na+].[Na+].[Na+].[Na+].CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N=NC3=C(O)C4=C(N)C=C(C=C4C=C3[S]([O-])(=O)=O)[S]([O-])(=O)=O)C)N=NC5=C(O)C6=C(N)C=C(C=C6C=C5[S]([O-])(=O)=O)[S]([O-])(=O)=O",-2.749,4,4,9]
["S6948","Lanreotide","d11","L3800-39","in 10mM DMSO","FDA, DMF, NDC","N/A","Marketed","GHSR","Endocrinology & Hormones","Lanreotide (Laromustine, Angiopeptin, BIM 23014, Dermopeptin, Ipstyl, ITM-014, Somatulina, Somatuline, Lanreotidum), an analog of the native somatostatin peptide, is a physiological inhibitor of growth hormone (GH). Lanreotide also has antitumoral effects.",1096.32,"108736-35-2",{"v":100,"d":"100.00"},91.21,{"v":100,"d":"100.00"},91.21,"https://www.selleckchem.com/products/lanreotide.html","C54H69N11O10S2","Free Base","Laromustine, Angiopeptin, BIM 23014, BIM 23014C, BM 23014, Dermopeptin, Ipstyl, ITM-014, ITM-014T, Somatulina, Somatuline, Lanreotidum","CC(C)C1NC(=O)C(CCCCN)NC(=O)C(CC2=C[NH]C3=C2C=CC=C3)NC(=O)C(CC4=CC=C(O)C=C4)NC(=O)C(CSSCC(NC1=O)C(=O)NC(C(C)O)C(N)=O)NC(=O)C(N)CC5=CC6=CC=CC=C6C=C5",1.704,8,13,17]
["S6955","Insulin (human)","e11","L3800-39","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","N/A","N/A","IGF-1R","Protein Tyrosine Kinase","Insulin (human) (Insulin regular) is a polypeptide hormone that regulates the level of glucose. Insulin is commonly used to treat hyperglycemia in patients with diabetes. Potency: 29 units/mg.",5807.57,"11061-68-0",{"v":100,"d":"100.00"},17.22,"<1","N/A","https://www.selleckchem.com/products/insulin.html","C257H383N65O77S6","Free Base","Insulin regular","N/A",0.734,0,0,0]
["S6963","APTO-253","a2","L3800-40","in 10mM DMSO","N/A","N/A","Phase 1","Apoptosis related,KLF,Myc,p21","Cell Cycle","APTO-253 (LOR-253, LT-253) inhibits c-Myc expression and selectively induces CDKN1A (p21), promotes G0-G1 cell-cycle arrest, and triggers apoptosis in acute myeloid leukemia (AML) cells. APTO-253 is also an inducer of KLF4 (Kr&uuml;ppel-like factor 4).",367.38,"916151-99-0",{"v":73,"d":"73.00"},{"v":198.7,"d":"198.70"},"<1","N/A","https://www.selleckchem.com/products/apto-253.html","C22H14FN5","Free Base","LOR-253, LT-253","CC1=C(C2=NC3=C([NH]2)C4=CC=CN=C4C5=C3C=CC=N5)C6=C([NH]1)C=CC(=C6)F",4.287,3,2,1]
["S8957","Navoximod","c2","L3800-40","in 10mM DMSO","N/A","N/A","Phase 1","IDO/TDO","Metabolism","Navoximod (GDC-0919, NLG-919) is a potent inhibitor of IDO (indoleamine-(2,3)-dioxygenase) pathway with Ki of 7 nM and EC50 of 75 nM.",316.37,"1402837-78-8",{"v":63,"d":"63.00"},199.13,"<1","N/A","https://www.selleckchem.com/products/navoximod.html","C18H21FN2O2","Free Base","GDC-0919, NLG-919","OC1CCC(CC1)C(O)CC2[N]3C=NC=C3C4=C2C(=CC=C4)F",2.224,1,2,3]
["S9296","Fraxin","f2","L3800-40","in 10mM DMSO","N/A","N/A","Phase 1","Immunology & Inflammation related","Immunology & Inflammation","Fraxin (Fraxetin-8-O-glucoside), a main active component isolated from Cortex Fraxini, possesses a variety of bioactivities such as anti-inflammatory, antioxidant, analgesic, antimicrobial, antiviral, immunomodulatory, anti-hyperuricemia and diuresis.",370.31,"524-30-1",{"v":74,"d":"74.00"},199.83,{"v":6,"d":"6.00"},{"v":16.2,"d":"16.20"},"https://www.selleckchem.com/products/fraxin.html","C16H18O10","Free Base","Fraxetin-8-O-glucoside","COC1=CC2=C(OC(=O)C=C2)C(=C1O)OC3OC(CO)C(O)C(O)C3O",-0.531,5,5,4]
["S9674","Saroglitazar","a3","L3800-40","in 10mM DMSO","marketed in India","N/A","Marketed","PPAR","Metabolism","Saroglitazar (Lipaglyn, ZYH1) is an agonist of peroxisome proliferator-activated receptor (PPAR) with EC50 of 0.65 pM and 3 nM for hPPARα and hPPARγ in HepG2 cells, respectively.",439.57,"495399-09-2","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","https://www.selleckchem.com/products/saroglitazar.html","C25H29NO4S","Free Base","Lipaglyn, ZYH1","CCOC(CC1=CC=C(OCC[N]2C(=CC=C2C3=CC=C(SC)C=C3)C)C=C1)C(O)=O",5.349,3,0,11]
["S9709","Muramyl dipeptide","e3","L3800-40","in 10mM DMSO","N/A","N/A","Phase 3","RUNX","Cell Cycle","Muramyl dipeptide (MDP) is a shared structural unit of peptidoglycans. Muramyl dipeptide is an inducer of bone formation through the induction of Runx2.",492.48,"53678-77-6",{"v":98,"d":"98.00"},198.99,{"v":98,"d":"98.00"},198.99,"https://www.selleckchem.com/products/muramyl-dipeptide.html","C19H32N4O11","Free Base","MDP","CC(NC(=O)C(C)OC1C(O)C(CO)OC(O)C1NC(C)=O)C(=O)NC(CCC(O)=O)C(N)=O",-4.245,7,6,12]
["S9718","TK216","h3","L3800-40","in 10mM DMSO","N/A","N/A","Phase 2","DNA/RNA Synthesis","DNA Damage/DNA Repair","TK216 is a potent inhibitor targeting E26 transformation specific (ETS) factors via blocking the protein-protein interaction with RNA helicases. TK216 exhibits antilymphoma activity.",376.23,"1903783-48-1",{"v":75,"d":"75.00"},199.35,"<1","N/A","https://www.selleckchem.com/products/tk216.html","C19H15Cl2NO3","Free Base","ONCT 216, SPH-8216","OC1(CC(=O)C2=CC=C(C=C2)C3CC3)C(=O)NC4=C(Cl)C=CC(=C14)Cl",3.785,2,1,4]
["S9719","CB-103","a4","L3800-40","in 10mM DMSO","N/A","N/A","Phase 2","Notch","Neuronal Signaling","CB-103 is an orally active inhibitor of the Notch transcription activation complex. CB-103 produces Notch loss-of-function phenotypes in flies and mice and inhibits the growth of human breast cancer and leukemia xenografts.",242.32,"218457-67-1",{"v":48,"d":"48.00"},198.09,"<1","N/A","https://www.selleckchem.com/products/cb-103.html","C15H18N2O","Free Base","N/A","CC(C)(C)C1=CC=C(OC2=CC=C(N)C=N2)C=C1",3.432,2,1,3]
["S0711","Canertinib dihydrochloride","d4","L3800-40","in 10mM DMSO","N/A","N/A","Phase 2","EGFR","Protein Tyrosine Kinase","Canertinib (CI-1033, PD-183805, compound 18) dihydrochloride is a potent and irreversible inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. Canertinib dihydrochloride inhibits cellular EGFR and ErbB2 autophosphorylation with IC50 of 7.4 nM and 9 nM, respectively.",558.86,"289499-45-2",{"v":100,"d":"100.00"},178.94,{"v":20,"d":"20.00"},35.79,"http://www.selleckchem.com/products/canertinib-dihydrochloride.html","C24H27Cl3FN5O3","Dihydrochloride","CI-1033 dihydrochloride, PD-183805 dihydrochloride","Cl.Cl.FC1=C(Cl)C=C(NC2=NC=NC3=CC(=C(NC(=O)C=C)C=C23)OCCCN4CCOCC4)C=C1",4.801,5,2,9]
["S1711","Crotamiton","g4","L3800-40","in 10mM DMSO","FDA, DMF, NDC, CFDA, PMDA","EP10.4, USP43-NF38","N/A","Others","Angiogenesis","Crotamiton is a drug that is used as a scabicidal (for treating scabies) and an antipruritic",203.28,"483-63-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/Crotamiton.html","C13H17NO","Free Base","N/A","CCN(C(=O)\\C=C\\C)C1=CC=CC=C1C",3.091,1,0,3]
["S3380","Tecovirimat","c5","L3800-40","in 10mM DMSO","FDA, NDC","N/A","Marketed","Antiviral","Immunology & Inflammation","Tecovirimat (Arestvyr, SIGA-246, ST-246, TPOXX) is an antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs. Tecovirimat is developed for the treatment of smallpox infection.",376.33,"869572-92-9",{"v":75,"d":"75.00"},199.29,"<1","N/A","http://www.selleckchem.com/products/tecovirimat.html","C19H15F3N2O3","Free Base","Arestvyr, SIGA-246, ST-246, TPOXX","FC(F)(F)C1=CC=C(C=C1)C(=O)NN2C(=O)C3C4C=CC(C5CC45)C3C2=O",2.018,3,1,3]
["S3498","Ecamsule.2Na","f5","L3800-40","in 10mM DMSO","N/A","DMF,FDA","N/A","Others","Others","Ecamsule.2Na is the Sodium salt form of Ecamsule. Ecamsule is an active ingredient of sunscreens that protects the skin from sunburn and erythema.",606.66,"90458-75-6",{"v":100,"d":"100.00"},164.84,{"v":100,"d":"100.00"},164.84,"http://www.selleckchem.com/products/ecamsule-2na.html","C28H32Na2O8S2","Free Base","N/A","[Na+].[Na+].CC1(C)C2CCC1(C[S]([O-])(=O)=O)C(=O)C2=CC3=CC=C(C=C3)C=C4C5CCC(C[S]([O-])(=O)=O)(C4=O)C5(C)C",-0.638,2,0,6]
["S3565","Brequinar Sodium","a6","L3800-40","in 10mM DMSO","N/A","N/A","Phase 2","Dehydrogenase","Metabolism","Brequinar Sodium (Bipenquinate, BRQ, DUP-785, NSC 368390) is a potent and selective dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of ~20 nM and triggers differentiation in the ER-HoxA9, U937, and THP1 cells with ED50 of ~1 μM.",397.35,"96201-88-6",{"v":79,"d":"79.00"},198.82,{"v":26,"d":"26.00"},65.43,"http://www.selleckchem.com/products/bipenquinate.html","C23H14F2NNaO2","Sodium","Bipenquinate, BRQ, DUP-785, NSC 368390","CC1=C(C(=O)O[Na])C2=CC(=CC=C2N=C1C3=CC=C(C=C3)C4=C(F)C=CC=C4)F",6.099,3,0,4]
["S3587","Mebrofenin","e6","L3800-40","in 10mM DMSO","FDA, DMF, NDC","USP43-NF38","N/A","Others","Others","Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA) that is available as a ready to use the kit for radio-labeling with Technetium-99m (Tc-99m). Tc-99m Mebrofenin is used clinical for hepatobiliary scintigraphy.",387.23,"78266-06-5",{"v":77,"d":"77.00"},198.85,"<1","N/A","http://www.selleckchem.com/products/mebrofenin.html","C15H19BrN2O5","Free Base","SQ 26962","CC1=C(Br)C(=C(NC(=O)CN(CC(O)=O)CC(O)=O)C(=C1)C)C",-0.909,3,1,7]
["S3590","Triolein","h6","L3800-40","in 10mM DMSO","DMF","EP10.4","N/A","Interleukins,MMP,ROS","Proteases","Triolein is an inhibitor of metalloproteinase-1 (MMP-1) and reduces both the expression of IL-6 and ROS generation in irradiated keratinocytes.",885.43,"122-32-7","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/triolein.html","C57H104O6","Free Base","N/A","CCCCCCCC\\C=C/CCCCCCCC(=O)OCC(COC(=O)CCCCCCC\\C=C/CCCCCCCC)OC(=O)CCCCCCC\\C=C/CCCCCCCC",20.925,6,0,53]
["S3592","4-Phenylbutyric acid (4-PBA)","a7","L3800-40","in 10mM DMSO","DMF","N/A","N/A","Autophagy,HDAC","DNA Damage/DNA Repair","4-Phenylbutyric acid (4-PBA, Benzenebutyric acid) is a histone deacetylase (HDAC) inhibitor and a key epigenetic inducer of anti-HCV hepatic hepcidin. 4-Phenylbutyric acid inhibits LPS-induced inflammation through regulating endoplasmic-reticulum (ER) stress and autophagy in acute lung injury models.",{"v":164.2,"d":"164.20"},"1821-12-1",{"v":33,"d":"33.00"},200.97,"<1","N/A","http://www.selleckchem.com/products/4-phenylbutyric-acid-4-pba-.html","C10H12O2","Free Base","Benzenebutyric acid","OC(=O)CCCC1=CC=CC=C1",2.407,1,0,4]
["S3595","D-Gluconic acid","d7","L3800-40","in 10mM DMSO","DMF, CFDA","USP43-NF38","N/A","Fungal","Microbiology","D-Gluconic acid is an antifungal agent.",196.16,"526-95-4","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/d-gluconic-acid.html","C6H12O7","Free Base","N/A","OCC(O)C(O)C(O)C(O)C(O)=O",-2.813,1,5,5]
["S3599","Resazurin sodium","g7","L3800-40","in 10mM DMSO","N/A","USP43-NF38","N/A","Dyes","Others","Resazurin sodium (Resazurin sodium salt, Diazoresorcinol sodium) is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.",251.17,"62758-13-8",{"v":50,"d":"50.00"},199.07,{"v":50,"d":"50.00"},199.07,"http://www.selleckchem.com/products/resazurin-sodium.html","C12H6NNaO4","Sodium","Resazurin sodium salt, Diazoresorcinol sodium","[Na+].[O-]C1=CC2=C(C=C1)[N+](=C3C=CC(=O)C=C3O2)[O-]",0.085,2,0,0]
["S4419","Ensulizole","c8","L3800-40","in 10mM DMSO","NDC","USP43-NF38","N/A","ROS","Immunology & Inflammation","Ensulizole (PBSA), a water soluble sunscreen ingredient, is a sulfonated UV absorber which is characterized by intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation.",{"v":274.3,"d":"274.30"},"27503-81-7",{"v":5,"d":"5.00"},18.23,"<1","N/A","http://www.selleckchem.com/products/ensulizole.html","C13H10N2O3S","Free Base","PBSA","O[S](=O)(=O)C1=CC2=C(C=C1)N=C([NH]2)C3=CC=CC=C3",2.603,1,1,2]
["S4426","Sacubitril hemicalcium salt","f8","L3800-40","in 10mM DMSO","FDA, DMF, EMA, NDC, PMDA","N/A","Discontinued","Neprilysin","Proteases","Sacubitril (AHU-377) hemicalcium salt, a component of the heart failure medicine LCZ696, is a potent inhibitor of neprilysin (neutral endopeptidase, NEP).",861.04,"1369773-39-6",{"v":100,"d":"100.00"},116.14,"<1","N/A","http://www.selleckchem.com/products/sacubitril-hemicalcium-salt.html","C48H56CaN2O10","Hemicalcium salt","AHU-377 hemicalcium salt","[Ca++].CCOC(=O)C(C)CC(CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC([O-])=O.CCOC(=O)C(C)CC(CC3=CC=C(C=C3)C4=CC=CC=C4)NC(=O)CCC([O-])=O",4.569,6,2,24]
["S4429","Edoxaban","a9","L3800-40","in 10mM DMSO","FDA, DMF, EMA, NDC, PMDA","N/A","Marketed","Factor Xa","Metabolism","Edoxaban (DU-176b, Savaysa), an antithrombotic agent, is a selective, potent and orally active inhibitor of factor Xa (FXa) with Ki of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively.",548.06,"480449-70-5",{"v":10,"d":"10.00"},18.25,"<1","N/A","https://www.selleckchem.com/products/edoxaban-du-176b.html","C24H30ClN7O4S","Free Base","DU-176b, Savaysa","CN1CCC2=C(C1)SC(=N2)C(=O)NC3CC(CCC3NC(=O)C(=O)NC4=NC=C(Cl)C=C4)C(=O)N(C)C",0.844,6,3,6]
["S4433","Eliglustat hemitartrate","d9","L3800-40","in 10mM DMSO","FDA, DMF, EMA, NDC, PMDA","N/A","Marketed","Glucosylceramide Synthase","Metabolism","Eliglustat hemitartrate (Genz-112638, Eliglustat tartrate) is a potent, specific and orally active inhibitor of glucosylceramide synthase with IC50 of 24 nM.",959.17,"928659-70-5",{"v":100,"d":"100.00"},104.26,{"v":100,"d":"100.00"},104.26,"http://www.selleckchem.com/products/eliglustat-hemitartrate.html","C50H78N4O14","Hemitartrate","Genz-112638, Eliglustat tartrate, Cerdelga","CCCCCCCC(=O)NC(CN1CCCC1)C(O)C2=CC3=C(OCCO3)C=C2.CCCCCCCC(=O)NC(CN4CCCC4)C(O)C5=CC6=C(OCCO6)C=C5.OC(C(O)C(O)=O)C(O)=O",-0.116,8,6,25]
["S4436","Pleuromutilin","g9","L3800-40","in 10mM DMSO","DMF","N/A","N/A","Antibiotics,Bacterial","Microbiology","Pleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.",{"v":378.5,"d":"378.50"},"125-65-5",{"v":76,"d":"76.00"},200.79,"<1","N/A","http://www.selleckchem.com/products/pleuromutilin.html","C22H34O5","Free Base","Drosophilin B, Mutilin 14-glycolate","CC1CCC23CCC(=O)C2C1(C)C(CC(C)(C=C)C(O)C3C)OC(=O)CO",2.372,3,2,4]
["S4438","Benzophenone","h9","L3800-40","in 10mM DMSO","DMF, NDC","USP36-NF31, IP2010","N/A","Others","Others","Benzophenone (Diphenyl ketone, Benzoylbenzene) filters out both UVA and UVB rays and is widely used in a great variety of sunscreens and personal care products.",182.22,"119-61-9",{"v":36,"d":"36.00"},197.56,"<1","N/A","http://www.selleckchem.com/products/benzophenone.html","C13H10O","Free Base","Diphenyl ketone, Benzoylbenzene","O=C(C1=CC=CC=C1)C2=CC=CC=C2",3.234,1,0,2]
["S4441","Isomalt","c10","L3800-40","in 10mM DMSO","DMF","EP10.4, USP43-NF38, JP17","N/A","LDH","Metabolism","Isomalt (Palatinitol) is a sugar alcohol used as an excipient in commercially available solid oral dosage forms. Isomalt stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying.",344.31,"64519-82-0",{"v":69,"d":"69.00"},{"v":200.4,"d":"200.40"},{"v":69,"d":"69.00"},{"v":200.4,"d":"200.40"},"http://www.selleckchem.com/products/isomalt.html","C12H24O11","Free Base","Palatinitol","OCC(O)C(O)C(O)C(O)COC1OC(CO)C(O)C(O)C1O",-4.688,2,9,8]
["S4447","Pipobroman","f10","L3800-40","in 10mM DMSO","FDA","N/A","N/A","DNA alkylator","DNA Damage/DNA Repair","Pipobroman (PB, Vercyte), a neutral amide of piperazine, acts as an alkylating agent with antiproliferative activity.",356.05,"54-91-1",{"v":71,"d":"71.00"},199.41,"<1","N/A","http://www.selleckchem.com/products/pipobroman.html","C10H16Br2N2O2","Free Base","PB, Vercyte","BrCCC(=O)N1CCN(CC1)C(=O)CCBr",0.647,2,0,4]
["S4486","Thiamine monochloride","b11","L3800-40","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38,KP Ⅹ, EP9.0, Ph.Int_6th, JP16, IP2010","N/A","Vitamin","Metabolism","Thiamine (Vitamin B1) monochloride is an essential vitamin that plays an important role in cellular production of energy from ingested food and enhances normal neuronal actives.",300.81,"59-43-8",{"v":60,"d":"60.00"},199.46,{"v":60,"d":"60.00"},199.46,"http://www.selleckchem.com/products/thiamine-monochloride.html","C12H17ClN4OS","Monochloride","Vitamin B1","[Cl-].CC1=NC=C(C[N+]2=CSC(=C2C)CCO)C(=N1)N",-1.626,2,2,4]
["S4490","Tetracycline","e11","L3800-40","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, JP17, Ph.Int_6th, IP2010","Discontinued","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Bacterial","Microbiology","Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites.",444.43,"60-54-8",{"v":89,"d":"89.00"},200.26,"<1","N/A","http://www.selleckchem.com/products/tetracycline.html","C22H24N2O8","Free Base","TC","CN(C)C1C2CC3C(=C(O)C4=C(C=CC=C4O)C3(C)O)C(=O)C2(O)C(=C(C(N)=O)C1=O)O",-1.011,3,4,2]
["S4496","Maltose monohydrate","a2","L3800-41","in 10mM DMSO","DMF, PMDA","EP10.5, USP43-NF38, KP Ⅹ, JP17","N/A","Others","Others","Maltose (Maltobiose, Malt Sugar, Beta-Maltose, D-Maltose) monohydrate, an non-essential nutrient that provides energy, is an intermediate in the intestinal digestion of glycogen and starch, and is found in germinating grains (and other plants and vegetables).",360.31,"6363-53-7",{"v":72,"d":"72.00"},199.83,{"v":72,"d":"72.00"},199.83,"http://www.selleckchem.com/products/maltose-monohydrate.html","C12H24O12","Monohydrate","Maltobiose, Malt Sugar, Beta-Maltose, D-Maltose","O.OCC(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)C(O)C=O",-4.745,3,8,8]
["S4681","Quinidine hydrochloride monohydrate","d2","L3800-41","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP17, IP2010","N/A","Potassium Channel","Transmembrane Transporters","Quinidine hydrochloride monohydrate is an anti-arrythmic agent and a potent potassium channel inhibitor with IC50 of 19.9 μM.",378.89,"6151-40-2",{"v":76,"d":"76.00"},200.59,{"v":10,"d":"10.00"},26.39,"http://www.selleckchem.com/products/quinidine-hydrochloride-monohydrate.html","C20H27ClN2O3","Hydrochloride monohydrate","N/A","O.Cl.COC1=CC2=C(C=CN=C2C=C1)C(O)C3CC4CCN3CC4C=C",2.908,2,1,4]
["S4842","Balsalazide","g2","L3800-41","in 10mM DMSO","FDA, DMF, CFDA, NDC","USP43-NF38","Marketed","Immunology & Inflammation related,Interleukins,STAT","Immunology & Inflammation","Balsalazide (Colazal, Giazo), an aminosalicylate and oral prodrug, is enzymatically cleaved in the colon to produce the anti-inflammatory agent mesalazine. Balsalazide suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway.",357.32,"80573-04-2",{"v":71,"d":"71.00"},{"v":198.7,"d":"198.70"},{"v":71,"d":"71.00"},{"v":198.7,"d":"198.70"},"http://www.selleckchem.com/products/balsalazide.html","C17H15N3O6","Free Base","Colazal, Giazo","OC(=O)CCNC(=O)C1=CC=C(C=C1)N=NC2=CC(=C(O)C=C2)C(O)=O",2.524,5,2,7]
["S4895","Nilotinib hydrochloride monohydrate","h2","L3800-41","in 10mM DMSO","FDA, DMF, EMA, NDC, PMDA","EP10.5","Marketed","AMPK,Autophagy,Bcr-Abl","Angiogenesis","Nilotinib (AMN-107, Tasigna) hydrochloride monohydrate is a selective and orally bioavailable inhibitor of Bcr-Abl with IC50 < 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.",583.99,"923288-90-8",{"v":100,"d":"100.00"},171.24,"<1","N/A","http://www.selleckchem.com/products/nilotinib-hydrochloride-monohydrate.html","C28H25ClF3N7O2","Hydrochloride monohydrate","Tasigna, AMN-107 hydrochloride monohydrate","O.Cl.CC1=C[N](C=N1)C2=CC(=CC(=C2)NC(=O)C3=CC(=C(C)C=C3)NC4=NC=CC(=N4)C5=CN=CC=C5)C(F)(F)F",5.259,5,2,7]
["S4945","Ethacridine lactate","c3","L3800-41","in 10mM DMSO","DMF, CFDA","EP10.5","N/A","Anti-infection,PARG","Immunology & Inflammation","Ethacridine lactate (Acrinol) is an aromatic organic compound based on acridine used as an antiseptic agent. Ethacridine lactate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.",343.38,"1837-57-6",{"v":69,"d":"69.00"},200.94,{"v":69,"d":"69.00"},200.94,"http://www.selleckchem.com/products/ethacridine-lactate.html","C18H21N3O4","Free Base","Acrinol","CCOC1=CC2=C(N)C3=C(C=C(N)C=C3)N=C2C=C1.CC(O)C(O)=O",{"v":1.8,"d":"1.800"},3,3,3]
["S4967","Ceritinib dihydrochloride","f3","L3800-41","in 10mM DMSO","FDA, DMF, EMA, NDC, PMDA","N/A","Marketed","ALK,IGF-1R,Serine/threonin kinase","Protein Tyrosine Kinase","Ceritinib (Zykadia, LDK378) dihydrochloride is a selective, orally bioavailable and ATP-competitive inhibitor of ALK with IC50 of 0.2 nM. Ceritinib dihydrochloride also inhibits InsR, IGF-1R and STK22D with IC50 of 7 nM, 8 nM and 23 nM, respectively. Ceritinib exhibits antitomor activity.",631.06,"1380575-43-8",{"v":13,"d":"13.00"},{"v":20.6,"d":"20.60"},"<1","N/A","http://www.selleckchem.com/products/ceritinib-dihydrochloride.html","C28H38Cl3N5O3S","Dihydrochloride","Zykadia, LDK378 dihydrochloride","Cl.Cl.CC(C)OC1=C(NC2=NC=C(Cl)C(=N2)NC3=CC=CC=C3[S](=O)(=O)C(C)C)C=C(C)C(=C1)C4CCNCC4",7.243,5,3,9]
["S5026","Irinotecan hydrochloride","b4","L3800-41","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","EP10.5, USP43-NF38, IP2010","Marketed","Topoisomerase","DNA Damage/DNA Repair","Irinotecan (CPT-11, (+)-Irinotecan) hydrochloride is an inhibitor of Topoisomerase I (Topo I) that exhibits cytotoxicity in LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively.",623.14,"100286-90-6",{"v":100,"d":"100.00"},160.48,"<1","N/A","http://www.selleckchem.com/products/irinotecan-hydrochloride.html","C33H39ClN4O6","Hydrochloride","CPT-11 hydrochloride, (+)-Irinotecan hydrochloride","Cl.CCC1=C2CN3C(=O)C4=C(C=C3C2=NC5=C1C=C(OC(=O)N6CCC(CC6)N7CCCCC7)C=C5)C(O)(CC)C(=O)OC4",4.068,6,0,5]
["S5184","Dexamethasone palmitate","e4","L3800-41","in 10mM DMSO","CFDA, PMDA","N/A","N/A","Anti-infection,Glucocorticoid Receptor","Endocrinology & Hormones","Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone (DXM), is a glucocorticoid receptor agonist with a 47-fold lower affinity for the glucocorticoid receptor than DXM. Dexamethasone palmitate (DXP) exhibits anti-inflammatory activity.",630.87,"14899-36-6",{"v":100,"d":"100.00"},158.51,"<1","N/A","http://www.selleckchem.com/products/dexamethasone-palmitate.html","C38H59FO6","Free Base","DXP","CCCCCCCCCCCCCCCC(=O)OCC(=O)C1(O)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C",8.684,4,1,18]
["S5188","Ribociclib succinate","a5","L3800-41","in 10mM DMSO","FDA, DMF, EMA, NDC","N/A","Marketed","CDK","Cell Cycle","Ribociclib (LEE011) succinate (Kisqali) is a highly specific dual inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM, respectively.",552.63,"1374639-75-4",{"v":100,"d":"100.00"},180.95,"<1","N/A","http://www.selleckchem.com/products/ribociclib-succinate.html","C27H36N8O5","Succinate","LEE011 succinate, Kisqali","CN(C)C(=O)C1=CC2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2[N]1C5CCCC5.OC(=O)CCC(O)=O",-0.164,6,2,8]
["S5191","Cinacalcet","d5","L3800-41","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","N/A","Marketed","Calcium Channel","Transmembrane Transporters","Cinacalcet (AMG073, Sensipar, Cin) is an orally active, allosteric agonist of receptors for calcium (CaR) that increases the sensitivity of the CaR to Ca.",357.41,"226256-56-0","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/cinacalcet.html","C22H22F3N","Free Base","AMG073, Sensipar, Cin","CC(NCCCC1=CC(=CC=C1)C(F)(F)F)C2=CC=CC3=CC=CC=C23",5.956,0,1,7]
["S5194","Furosemide sodium","g5","L3800-41","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, Ph.Int_6th, IP2010","Discontinued","GABA Receptor,NKCC","Transmembrane Transporters","Furosemide (Frusemide) sodium is a potent and orally active inhibitor of Na-K-Cl cotransporter (NKCC). Furosemide sodium is a subtype-selective antagonist of gamma-aminobutyric acid type A (GABAA) receptor.",352.73,"41733-55-5",{"v":71,"d":"71.00"},201.29,{"v":71,"d":"71.00"},201.29,"http://www.selleckchem.com/products/furosemide-sodium.html","C12H10ClN2NaO5S","Sodium","Lasix, Frusemide Sodium","[Na+].N[S](=O)(=O)C1=C(Cl)C=C(NCC2=CC=CO2)C(=C1)C([O-])=O",-0.071,3,2,5]
["S5195","Rucaparib Camsylate","h5","L3800-41","in 10mM DMSO","FDA, DMF, EMA, NDC","N/A","N/A","PARP","DNA Damage/DNA Repair","Rucaparib (Rubraca, AG014699, PF01367338) Camsylate is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains.",555.66,"1859053-21-6",{"v":100,"d":"100.00"},179.97,"<1","N/A","http://www.selleckchem.com/products/rucaparib-camsylate.html","C29H34FN3O5S","Camsylate","Rubraca, AG014699 Camsylate, PF01367338 Camsylate","CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=C3C(=CC(=C4)F)[NH]2.CC5(C)C6CCC5(C[S](O)(=O)=O)C(=O)C6",3.888,2,3,5]
["S5219","Allylestrenol","c6","L3800-41","in 10mM DMSO","CFDA, PMDA","N/A","N/A","Estrogen/progestogen Receptor","Endocrinology & Hormones","Allylestrenol is an orally active progestagen of the 19-nortestosterone series resembling progesterone.",300.48,"432-60-0",{"v":60,"d":"60.00"},199.68,"<1","N/A","http://www.selleckchem.com/products/allylestrenol.html","C21H32O","Free Base","N/A","CC12CCC3C(CCC4=CCCCC34)C1CCC2(O)CC=C",5.062,0,0,2]
["S5489","Prednisone acetate","g6","L3800-41","in 10mM DMSO","FDA, DMF, CFDA, NDC","EP10.5, USP43-NF38, IP2010","N/A","Glucocorticoid Receptor","Endocrinology & Hormones","Prednisone acetate (Betapar, Cortan, Deltasone, Fernisone, Meticorten, Prednisone 21-acetate) is a glucocorticoid steroid that can be used as a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties.",400.46,"125-10-0",{"v":27,"d":"27.00"},67.42,"<1","N/A","http://www.selleckchem.com/products/prednisone-acetate.html","C23H28O6","Free Base","Betapar, Cortan, Deltasone, Fernisone, Meticorten, Prednisone 21-acetate","CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)C=CC4(C)C3C(=O)CC12C",1.596,5,0,4]
["S5608","Pantoprazole sodium hydrate","a7","L3800-41","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC","EP10.5, USP43-NF38, IP2010","Marketed","ATPase,Proton Pump","Transmembrane Transporters","Pantoprazole (BY10232, SKF96022) sodium hydrate (Protonix) is a potent inhibitor of H+/K(+)-ATPase with IC50 of 6.8 μM.",864.75,"164579-32-2",{"v":100,"d":"100.00"},115.64,{"v":17,"d":"17.00"},19.66,"http://www.selleckchem.com/products/pantoprazole-sodium-hydrate.html","C32H34F4N6Na2O11S2","Sodium hydrate","Protonix, BY1023 sodium hydrate, SKF96022 sodium hydrate","O.O.O.[Na+].[Na+].COC1=C(OC)C(=NC=C1)C[S](=O)C2=NC3=C([N-]2)C=CC(=C3)OC(F)F.COC4=C(OC)C(=NC=C4)C[S](=O)C5=NC6=C([N-]5)C=CC(=C6)OC(F)F",5.145,12,0,14]
["S5738","Megestrol","d7","L3800-41","in 10mM DMSO","FDA, DMF, CFDA, NDC","EP10.5, USP43-NF38, KP Ⅹ, IP2010","Phase 1","Estrogen/progestogen Receptor","Endocrinology & Hormones","Megestrol, a synthetic progestin, is approved for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with an acquired immunodeficiency syndrome diagnosis. Megestrol acetate (Megace) is one of the first progestational agents to be evaluated for use in the hormonal therapy of advanced breast cancer.",342.47,"3562-63-8",{"v":68,"d":"68.00"},198.56,"<1","N/A","http://www.selleckchem.com/products/megestrol.html","C22H30O3","Free Base","Megace","CC(=O)C1(O)CCC2C3C=C(C)C4=CC(=O)CCC4(C)C3CCC12C",3.126,2,0,1]
["S5786","Bromfenac sodium hydrate","h7","L3800-41","in 10mM DMSO","FDA, DMF, EMA, CFDA, NDC, PMDA","N/A","Marketed","COX","Immunology & Inflammation","Bromfenac sodium hydrate (Bromsite, Bromday, Prolensa, Xibrom), a brominated nonsteroidal anti-inflammatory drugs (NSAID) with strong in vitro anti-inflammatory potency, is a potent and orally active inhibitor of COX with IC50 of 5.56 nM and 7.45 nM for COX-1 and COX-2, respectively.",766.34,"120638-55-3",{"v":100,"d":"100.00"},130.49,{"v":100,"d":"100.00"},130.49,"http://www.selleckchem.com/products/bromfenac-sodium-hydrate.html","C30H28Br2N2Na2O9","Sodium hydrate","Bromsite, Bromday, Prolensa, Xibrom","O.O.O.[Na+].[Na+].NC1=C(CC([O-])=O)C=CC=C1C(=O)C2=CC=C(Br)C=C2.NC3=C(CC([O-])=O)C=CC=C3C(=O)C4=CC=C(Br)C=C4",2.231,2,2,8]
["S5864","Levocetirizine","c8","L3800-41","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","N/A","Marketed","Histamine Receptor","Neuronal Signaling","Levocetirizine (LCZ, (R)-Cetirizine), the R-enantiomer of cetirizine, is an antagonist of histamine H(1) receptor.",388.89,"130018-77-8",{"v":78,"d":"78.00"},200.57,{"v":78,"d":"78.00"},200.57,"http://www.selleckchem.com/products/levocetirizine.html","C21H25ClN2O3","Free Base","LCZ, (R)-Cetirizine","OC(=O)COCCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(Cl)C=C3",0.453,2,0,8]
["S5922","L-Carnitine hydrochloride","f8","L3800-41","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38","Marketed","Leukotriene","Metabolism","L-Carnitine ((R)-Carnitine, Levocarnitine) hydrochloride improves oxygen saturation, and inhibits leukotriene synthesis. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation.",197.66,"6645-46-1",{"v":40,"d":"40.00"},202.37,{"v":40,"d":"40.00"},202.37,"http://www.selleckchem.com/products/l-carnitine-hydrochloride.html","C7H16ClNO3","Hydrochloride","(R)-Carnitine hydrochloride, Levocarnitine hydrochloride","[Cl-].C[N+](C)(C)CC(O)CC(O)=O",{"v":-4.49,"d":"-4.490"},1,1,4]
["S5937","DL-Carnitine","g8","L3800-41","in 10mM DMSO","DMF","N/A","N/A","Others","Others","DL-Carnitine ((±)-Carnitin) is a racemic mixture of L-Carnitine and D-Carnitine that regulates fatty acid transport in the mitochondrion. DL-carnitine is found to be ineffective or toxic, for example, to muscle cells and to the myocardium. DL-Carnitine causes symptoms of myasthenia and cardiac arrhythmias.",{"v":161.2,"d":"161.20"},"461-06-3, 406-76-8",{"v":32,"d":"32.00"},198.51,{"v":32,"d":"32.00"},198.51,"http://www.selleckchem.com/products/dl-carnitine.html","C7H15NO3","Free Base","(±)-Carnitin","C[N+](C)(C)CC(O)CC([O-])=O",{"v":-3.29,"d":"-3.290"},0,1,4]
["S5947","Amitriptyline","b9","L3800-41","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.4, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP17, IP2010","N/A","5-HT Receptor,Histamine Receptor,Serotonin Transporter","Neuronal Signaling","Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. Amitriptyline is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. This product is a waxy solid.",{"v":277.4,"d":"277.40"},"50-48-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/amitriptyline.html","C20H23N","Free Base","MK-230, N-750, Ro41575","CN(C)CC\\C=C1/C2=C(CCC3=CC=CC=C13)C=CC=C2",4.772,0,0,3]
["S5955","Thiamine nitrate","f9","L3800-41","in 10mM DMSO","FDA, DMF, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP17, IP2010","N/A","Vitamin","Metabolism","Thiamine (Vitamin B1) nitrate is an essential vitamin that plays an important role in cellular production of energy from ingested food and enhances normal neuronal actives.",327.36,"532-43-4",{"v":65,"d":"65.00"},198.56,{"v":20,"d":"20.00"},61.09,"http://www.selleckchem.com/products/thiamine-nitrate.html","C12H17N5O4S","Nitrate","Vitamin B1 nitrate","CC1=NC=C(C[N+]2=CSC(=C2C)CCO)C(=N1)N.[O-][N+]([O-])=O",-0.914,2,2,4]
["S5959","Tenofovir Disoproxil","a10","L3800-41","in 10mM DMSO","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","Ph.Int_6th, IP2010","Marketed","HIV,Reverse Transcriptase","Microbiology","Tenofovir Disoproxil (Bis(POC)-PMPA, GS 4331) is a prodrug of tenofovir, which is metabolised intracellularly to its active anabolite tenofovir diphosphate, a competitive inhibitor of HIV-1 reverse transcriptase and terminates the growing DNA chain.",519.44,"201341-05-1",{"v":100,"d":"100.00"},192.52,"<1","N/A","http://www.selleckchem.com/products/tenofovir-disoproxil.html","C19H30N5O10P","Free Base","Bis(POC)-PMPA, GS 4331","CC(C)OC(=O)OCO[P](=O)(COC(C)C[N]1C=NC2=C(N)N=CN=C12)OCOC(=O)OC(C)C",{"v":1.69,"d":"1.690"},12,1,17]
["S5965","Urapidil","d10","L3800-41","in 10mM DMSO","DMF, CFDA, PMDA","JP17","N/A","5-HT Receptor,Adrenergic Receptor","Neuronal Signaling","Urapidil is an antihypertensive drug acting as an α1 adrenoreceptor antagonist and a 5-HT1A agonist.",387.48,"34661-75-1",{"v":77,"d":"77.00"},198.72,"<1","N/A","http://www.selleckchem.com/products/urapidil.html","C20H29N5O3","Free Base","N/A","COC1=CC=CC=C1N2CCN(CCCNC3=CC(=O)N(C)C(=O)N3C)CC2",1.426,3,1,7]
["S5972","Hydrocortisone hemisuccinate","h10","L3800-41","in 10mM DMSO","DMF","USP43-NF38, KP Ⅹ, JP17, IP2010","Marketed","Interleukins","Immunology & Inflammation","Hydrocortisone hemisuccinate (A-hydrocort, Hydrocortisone 21-hemisuccinate), a physiological glucocorticoid with anti-inflammatory properties, is an inhibitor of proinflammatory cytokine with IC50 of 6.7 μM and 21.4 μM for Interleukin-6 (IL-6) and IL-3, respectively.",462.53,"2203-97-6",{"v":93,"d":"93.00"},201.07,"<1","N/A","http://www.selleckchem.com/products/hydrocortisone-hemisuccinate.html","C25H34O8","Hemisuccinate","A-hydrocort, Hydrocortisone 21-hemisuccinate","CC12CCC(=O)C=C1CCC3C4CCC(O)(C(=O)COC(=O)CCC(O)=O)C4(C)CC(O)C23",1.507,5,1,7]
["S6359","Purine","c11","L3800-41","in 10mM DMSO","DMF","USP43-NF38, IP2010","N/A","DNA/RNA Synthesis","DNA Damage/DNA Repair","Purine is a heterocyclic aromatic organic compound which plays crucial roles in DNA and RNA. It is also significant components in a number of other important biomolecules, such as ATP, GTP, cyclic AMP, NADH, and coenzyme A.",120.11,"120-73-0",{"v":24,"d":"24.00"},199.81,"N/A","N/A","https://www.selleckchem.com/products/purine.html","C5H4N4","Free Base","N/A","[NH]1C=NC2=C1N=CN=C2",-0.235,3,1,0]
["S6466","Eicosapentaenoic acid ethyl ester","f11","L3800-41","in 10mM DMSO","FDA, DMF, NDC, PMDA","N/A","Marketed","Fatty Acid Synthase","Metabolism","Eicosapentaenoic acid ethyl ester (AMR101, EPA ethyl ester, Ethyl eicosapentaenoate) is an omega-3 fatty acid agent that significantly reduces the triglyceride (TG) levels and improves other lipid parameters without significantly increasing the low-density lipoprotein (LDL) cholesterol levels.",{"v":330.5,"d":"330.50"},"86227-47-6","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","N/A","http://www.selleckchem.com/products/eicosapentaenoic-acid-ethyl-ester.html","C22H34O2","Free Base","AMR101, EPA ethyl ester, Ethyl eicosapentaenoate","CCOC(=O)CCC\\C=C/C/C=C\\C\\C=C/C/C=C\\C\\C=C/CC",6.569,2,0,15]
["S6584","Amdinocillin","g11","L3800-41","in 10mM DMSO","DMF","N/A","Preclinical","Antibiotics,Bacterial","Microbiology","Amdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms.",325.43,"32887-01-7",{"v":65,"d":"65.00"},199.74,{"v":65,"d":"65.00"},199.74,"http://www.selleckchem.com/products/amdinocillin.html","C15H23N3O3S","Free Base","Mecillinam, Coactin, FL 1060","CC1(C)SC2C(N=CN3CCCCCC3)C(=O)N2C1C(O)=O",1.186,3,0,3]
["S7220","Fostemsavir","b2","L3800-42","in 10mM DMSO","FDA, EMA, NDC","N/A","Registered","gp120/CD4","Immunology & Inflammation","Fostemsavir (BMS-663068, Rukobia), the phosphonooxymethyl prodrug of BMS626529, is an attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells with EC50 of < 10 nM.",583.49,"864953-29-7",{"v":100,"d":"100.00"},171.38,"<1","N/A","http://www.selleckchem.com/products/bms-663068.html","C25H26N7O8P","Free Base","BMS-663068, Rukobia","COC1=CN=C([N]2C=NC(=N2)C)C3=C1C(=C[N]3CO[P](O)(O)=O)C(=O)C(=O)N4CCN(CC4)C(=O)C5=CC=CC=C5",0.752,8,0,8]
["S8956","(Z)-4-Hydroxytamoxifen","f2","L3800-42","in 10mM DMSO","N/A","N/A","Phase 2","Estrogen/progestogen Receptor","Endocrinology & Hormones","(Z)-4-Hydroxytamoxifen ((Z)-4-OHT, trans-4-Hydroxytamoxifen, 4-Monohydroxytamoxifen) is a selective modulator of estrogen receptor (SERM) with IC50 of 3.3 nM for the [3H]oestradiol binding to oestrogen receptor.",387.51,"68047-06-3",{"v":78,"d":"78.00"},201.29,"<1","N/A","http://www.selleckchem.com/products/z-4-hydroxytamoxifen.html","C26H29NO2","Free Base","(Z)-4-OHT, trans-4-Hydroxytamoxifen, 4-Monohydroxytamoxifen","CC/C(C1=CC=CC=C1)=C(C2=CC=C(O)C=C2)/C3=CC=C(OCCN(C)C)C=C3",6.077,1,1,8]
["S9667","Inobrodib (CCS-1477)","a3","L3800-42","in 10mM DMSO","N/A","N/A","Phase 1/2","Androgen Receptor,Epigenetic Reader Domain,Myc","Epigenetics","Inobrodib (CCS1477; CBP-IN-1; CBP/p300-IN-4）is a potent and selective inhibitor of p300/CBP bromodomain. CCS1477 works by inhibiting the expression and function of the androgen receptor (AR), as well as inhibiting c-Myc.",{"v":534.6,"d":"534.60"},"2222941-37-7",{"v":100,"d":"100.00"},187.06,"<1","N/A","http://www.selleckchem.com/products/ccs-1477-cbp-in-1-.html","C30H32F2N4O3","Free Base","CBP-IN-1, CBP/p300-IN-4","COC1CCC(CC1)[N]2C(=NC3=CC(=CC=C23)C4=C(C)ON=C4C)C5CCCC(=O)N5C6=CC(=C(F)C=C6)F",5.343,5,0,5]
["S9721","Farudodstat","d3","L3800-42","in 10mM DMSO","N/A","N/A","Phase 2","AP-1,Apoptosis related,Dehydrogenase","Metabolism","Farudodstat(LAS 186323,ASLAN003) is a potent and orally active inhibitor of DHODH (Dihydroorotate dehydrogenase) with IC50 of 35 nM for human DHODH enzyme activity. ASLAN003 impairs protein synthesis and induces the differentiation and apoptosis transcriptional program in acute myeloid leukemia (AML) cells via activation of AP-1 transcription factors.",356.32,"1035688-66-4",{"v":71,"d":"71.00"},199.26,"<1","N/A","http://www.selleckchem.com/products/aslan003.html","C19H14F2N2O3","Free Base","LAS 186323,ASLAN003","COC1=CC=CC(=C1)C2=CC(=C(NC3=NC=CC=C3C(O)=O)C(=C2)F)F",4.311,3,1,5]
["S9827","Iodoacetamide","h3","L3800-42","in 10mM DMSO","N/A","EP10.5","N/A","Others","Others","Iodoacetamide (IA, IAM, 2-Iodoacetamide) is an alkylating agent that is commonly used for alkylation of cysteine during sample preparation for proteomics.",184.96,"144-48-9",{"v":40,"d":"40.00"},216.26,{"v":40,"d":"40.00"},216.26,"http://www.selleckchem.com/products/iodoacetamide.html","C2H4INO","Free Base","IA, IAM, 2-Iodoacetamide","NC(=O)CI",0.376,1,1,1]
["S0081","DDD107498","c4","L3800-42","in 10mM DMSO","N/A","N/A","Phase 2","Parasite","Microbiology","DDD107498 (M-5717, DDD-498) is a P. falciparum translation elongation factor 2 inhibitor. DDD107498 exhibits a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite.",462.56,"1469439-69-7",{"v":93,"d":"93.00"},201.05,{"v":93,"d":"93.00"},201.05,"http://www.selleckchem.com/products/ddd107498.html","C27H31FN4O2","Free Base","M-5717, DDD-498","FC1=CC2=C(C=C1)N=C(C=C2C(=O)NCCN3CCCC3)C4=CC=C(CN5CCOCC5)C=C4",3.737,3,1,7]
["S0272","Derenofylline (SLV320)","d4","L3800-42","in 10mM DMSO","N/A","N/A","Phase 2","Adenosine Receptor","GPCR & G Protein","Derenofylline (SLV320) is a selective and potent adenosine A1 antagonist with Ki of 1 nM. Derenofylline shows selective for adenosine A1 over A2A, A2B, and A3 receptors with Ki of 398 nM, 3981 nM, and 200 nM, respectively.",308.38,"251945-92-3",{"v":62,"d":"62.00"},201.05,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/derenofylline.html","C18H20N4O","Free Base","N/A","OC1CCC(CC1)NC2=NC(=NC3=C2C=C[NH]3)C4=CC=CC=C4",3.133,2,3,3]
["S0343","Eprotirome (KB2115)","f4","L3800-42","in 10mM DMSO","N/A","N/A","Phase 3","THR","Metabolism","Eprotirome (KB2115) is a liver-selective agonist of thyroid hormone receptor (TR). Eprotirome is investigated for the potential treatment of dyslipidemias and obesity.",487.14,"355129-15-6",{"v":97,"d":"97.00"},199.12,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/eprotirome.html","C18H17Br2NO5","Free Base","N/A","CC(C)C1=C(O)C=CC(=C1)OC2=C(Br)C=C(NC(=O)CC(O)=O)C=C2Br",{"v":4.77,"d":"4.770"},3,2,6]
["S3572","BMS-986020","a5","L3800-42","in 10mM DMSO","N/A","N/A","Phase 2","LPA Receptor","GPCR & G Protein","BMS-986020 (AM152, AP-3152 free acid) is a potent and selective antagonist of lysophosphatidic acid receptor 1 (LPA1). BMS-986020 inhibits bile acid and phospholipid transporters with IC50 of 4.8 μM, 6.2 μM, and 7.5 μM for BSEP, MRP4, and MDR3, respectively. BMS-986020 has the potential for the treatment of idiopathic pulmonary fibrosis (IPF).",482.53,"1257213-50-5",{"v":97,"d":"97.00"},201.02,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/bms-986020.html","C29H26N2O5","Free Base","AM152, AP-3152 free acid","CC(OC(=O)NC1=C(ON=C1C)C2=CC=C(C=C2)C3=CC=C(C=C3)C4(CC4)C(O)=O)C5=CC=CC=C5",5.791,5,1,8]
["S6304","KL001","e5","L3800-42","in 10mM DMSO","N/A","N/A","Phase 1","Others","Others","KL001 is a stabilizer that specifically interacts with cryptochrome (CRY). KL001 prevents ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period.",398.48,"309928-48-1",{"v":80,"d":"80.00"},200.76,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/kl001.html","C21H22N2O4S","Free Base","N/A","C[S](=O)(=O)N(CC(O)C[N]1C2=CC=CC=C2C3=CC=CC=C13)CC4=CC=CO4",2.972,3,1,7]
["S6884","LY3405105","h5","L3800-42","in 10mM DMSO","N/A","N/A","Phase 1","CDK","Cell Cycle","LY3405105 is an orally active CDK7 inhibitor with an IC50 of 92.8 nM. LY3405105 shows potential antineoplastic activity.",497.63,"2326428-25-3",{"v":99,"d":"99.00"},198.94,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/ly3405105.html","C26H39N7O3","Free Base","N/A","CC(C)C1=C2N=C(C)C=C(NC3CCN(CC3)C(=O)OC4CCN(C4)C(=O)\\C=C\\CN(C)C)[N]2N=C1",1.936,5,1,8]
["S6981","Glycerol phenylbutyrate","c6","L3800-42","in 10mM DMSO","FDA, DMF, EMA,NDC","N/A","Marketed","Sigma Receptor","GPCR & G Protein","Glycerol phenylbutyrate (GT4P, HPN-100M, Ravicti) is a nitrogen-binding agent and acts as a sigma-2 (σ2) receptor ligand with a pKi of 8.02. Glycerol phenylbutyrate is a prodrug in which phenylbutyrate (PBA) is released from the glycerol backbone by lipases in the gastrointestinal tract.",530.65,"611168-24-2","The physical form of the compound is liquid, which can be dissolved in any proportion.",{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/glycerol-phenylbutyrate.html","C33H38O6","Free Base","GT4P, HPN-100M, Ravicti","O=C(CCCC1=CC=CC=C1)OCC(COC(=O)CCCC2=CC=CC=C2)OC(=O)CCCC3=CC=CC=C3",7.563,6,0,20]
["S8668","Inavolisib (GDC-0077)","g6","L3800-42","in 10mM DMSO","N/A","N/A","Phase 2/3","PI3K","PI3K/Akt/mTOR","Inavolisib (GDC-0077, RG6114, RO-7113755) is a potent selective inhibitor of PI3K alpha (PI3Kα) with an IC50 of 0.038 nM. GDC-0077 is >300-fold more selective for PI3K alpha over the other class I PI3K isoforms (beta, delta, and gamma) and >2000-fold more selective over PIK family members. GDC-0077 binds to the ATP binding site of PI3K and inhibits the phosphorylation of PIP2 to PIP3.",407.37,"2060571-02-8",{"v":81,"d":"81.00"},198.84,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/gdc-0077.html","C18H19F2N5O4","Free Base","RG6114, RO-7113755","CC(NC1=CC=C2C(=C1)OCC[N]3C=C(N=C23)N4C(COC4=O)C(F)F)C(N)=O",1.666,5,2,5]
["S9776","AG-636","b7","L3800-42","in 10mM DMSO","N/A","N/A","Phase 1","Dehydrogenase","Metabolism","AG-636 is an orally available inhibitor of dihydroorotate dehydrogenase (DHODH) with potential antineoplastic activity.",343.38,"1623416-31-8",{"v":35,"d":"35.00"},101.93,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/ag-636.html","C21H17N3O2","Free Base","N/A","C[N]1N=NC2=CC(=CC(=C12)C(O)=O)C3=CC=C(C=C3)C4=CC=CC=C4C",4.793,3,0,3]
["S9779","Emavusertib (CA-4948)","c7","L3800-42","in 10mM DMSO","N/A","N/A","Phase 2","FLT3,IRAK","Immunology & Inflammation","Emavusertib (CA-4948) is a potent and orally bioavailable inhibitor of interleukin-1 receptor-associated kinase 4/FMS-like Tyrosine Kinase 3 (IRAK4/FLT3) with anti-tumor activity.",{"v":491.5,"d":"491.50"},"1801344-14-8",{"v":49,"d":"49.00"},99.69,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/ca-4948.html","C24H25N7O5","Free Base","N/A","CC1=NC=CC(=C1)C2=NC(=CO2)C(=O)NC3=C(N=C4N=C(OC4=C3)N5CCOCC5)N6CCC(O)C6",1.031,8,2,5]
["S9885","MYLS22","f7","L3800-42","in 10mM DMSO","N/A","N/A","Phase 4","Others","Others","MYLS22  is a first-in-class and selective inhibitor of optic atrophy 1 (OPA1) with anti-angiogenesis and anti-cancer activity.",443.52,"306959-01-3",{"v":81,"d":"81.00"},182.63,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/myls22.html","C24H21N5O2S","Free Base","N/A","CN1N(C(=O)C(=C1C)NC(=O)C2=CC3=C(S2)[N](N=C3C)C4=CC=CC=C4)C5=CC=CC=C5",3.247,3,1,4]
["S9948","Danicamtiv (MYK-491)","a8","L3800-42","in 10mM DMSO","N/A","N/A","Phase 2","Cardiac Myosin","Cytoskeletal Signaling","Danicamtiv (MYK-491, SAR 440181) is a novel cardiac myosin activator that enhances cardiomyocyte contraction.",435.42,"1970972-74-7",{"v":87,"d":"87.00"},199.81,"<1",{"v":0,"d":"0.00"},"http://www.selleckchem.com/products/danicamtiv-myk-491.html","C16H20F3N5O4S","Free Base","SAR 440181","C[N]1C=C(C(=N1)C(F)F)[S](=O)(=O)C(C)(F)C2CCN(CC2)C(=O)NC3=NOC=C3",1.568,6,1,5]
["E0019","Dipivefrin Hydrochloride","e8","L3800-42","in 10mM DMSO","FDA, DMF, CFDA","USP–NF 2021(Issue 2), EP10.4","Preclinical","Others","Others","Dipivefrin (Dipivefrine,  Propine, Pivalephrine) is a prodrug of epinephrine which is hydrolyzed to epinephrine after absorption into the eye.",{"v":387.9,"d":"387.90"},"64019-93-8",{"v":78,"d":"78.00"},201.08,{"v":78,"d":"78.00"},201.08,"http://www.selleckchem.com/products/dipivefrin-hydrochloride.html","C19H30ClNO5","Hydrochloride","Dipivefrine,  Propine, Pivalephrine","Cl.CNCC(O)C1=CC(=C(OC(=O)C(C)(C)C)C=C1)OC(=O)C(C)(C)C",3.866,4,2,9]
["S0019","JNJ-10229570","h8","L3800-42","in 10mM DMSO","N/A","N/A","Phase 2","Melanocortin Receptor","GPCR & G Protein","JNJ-10229570 (UNII-N9IX402L35) is a potent MC1R and MC5R antagonist.",389.47,"524923-88-4",{"v":78,"d":"78.00"},200.27,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/jnj-10229570.html","C22H19N3O2S","Free Base","UNII-N9IX402L35","COC1=CC=CC=C1N2SC(=NC3=CC=CC=C3)N=C2C4=CC=CC=C4OC",{"v":5.67,"d":"5.670"},4,0,5]
["S0897","Cyclizine","c9","L3800-42","in 10mM DMSO","FDA, CFDA","USP–NF 2021(Issue 2), EP10.5, IP2010","N/A","Histamine Receptor","Neuronal Signaling","Cyclizine is a piperazine first-generation antagonist of histamine 1 receptor.",266.38,"82-92-8",{"v":53,"d":"53.00"},198.96,"<1","N/A","http://www.selleckchem.com/products/cyclizine.html","C18H22N2","Free Base","N/A","CN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3",{"v":3.47,"d":"3.470"},0,0,3]
["S6764","Pamufetinib (TAS-115)","g9","L3800-42","in 10mM DMSO","N/A","N/A","Phase III","c-Met,VEGFR","Protein Tyrosine Kinase","Pamufetinib (TAS-115) is a highly potent c-Met and VEGFR dual inhibitor with IC50s of 30 nM and 32 nM for recombinant VEGFR2 and recombinant MET, respectively.",518.56,"1190836-34-0",{"v":50,"d":"50.00"},96.42,"<1","N/A","http://www.selleckchem.com/products/tas-115.html","C27H23FN4O4S","Free Base","N/A","CNC(=O)C1=C(OC)C=C2N=CC=C(OC3=CC=C(NC(=S)NC(=O)CC4=CC=CC=C4)C=C3F)C2=C1",{"v":4.94,"d":"4.940"},5,3,9]
["S7454","Azemiglitazone (MSDC-0602)","b10","L3800-42","in 10mM DMSO","N/A","N/A","Phase II","Mitochondrial pyruvate carrier","Metabolism","Azemiglitazone (MSDC-0602) is a direct mitochondrial pyruvate carrier (MPC) inhibitor that modulates central carbon metabolism in mice and humans.",371.41,"1133819-87-0",{"v":82,"d":"82.00"},220.78,"<1","N/A","http://www.selleckchem.com/products/azemiglitazone-msdc-0602.html","C19H17NO5S","Free Base","N/A","COC1=CC=CC(=C1)C(=O)COC2=CC=C(CC3SC(=O)NC3=O)C=C2",{"v":3.31,"d":"3.310"},5,1,7]
["S9625","Saquinavir (Ro 31-8959)","c10","L3800-42","in 10mM DMSO","FDA, EMA, PMDA","USP–NF 2021(Issue 2), EP10.5, Ph.Int_6th, IP2010","Marketed","HIV Protease","Microbiology","Saquinavir (Ro 31-8959,SAQ) is a potent and selective inhibitor of HIV proteinase with a mean IC50 of 2.7 nM in JM cells.",670.84,"127779-20-8",{"v":100,"d":"100.00"},149.07,"<1","N/A","http://www.selleckchem.com/products/saquinavir.html","C38H50N6O5","Free Base","Ro 31-8959,SAQ","CC(C)(C)NC(=O)C1CC2CCCCC2CN1CC(O)C(CC3=CC=CC=C3)NC(=O)C(CC(N)=O)NC(=O)C4=NC5=CC=CC=C5C=C4",{"v":3.67,"d":"3.670"},5,5,13]
["S9896","JNJ-67856633","f10","L3800-42","in 10mM DMSO","N/A","N/A","Phase 1","MALT","Proteases","JNJ-67856633 (JNJ-6633) is a potent, selective, allosteric inhibitor of MALT1 protease.",467.32,"2230273-76-2",{"v":93,"d":"93.00"},199.01,"<1","N/A","http://www.selleckchem.com/products/jnj-67856633.html","C20H11F6N5O2","Free Base","JNJ-6633","FC(F)(F)C1=NC=CC(=C1)NC(=O)C2=C([N](N=C2)C3=CC=CC4=C3C=CNC4=O)C(F)(F)F",{"v":3.19,"d":"3.190"},4,2,5]
["E0037","Bradykinin","a11","L3800-42","in 10mM DMSO","NDC","N/A","N/A","Others","Others","Bradykinin is a potent vasodilator peptide that exerts its vasodilatory action through stimulation of specific endothelial B2 receptors, thereby causing the release of prostacyclin, NO, and EDHF.",1060.21,"58-82-2",{"v":100,"d":"100.00"},94.32,{"v":100,"d":"100.00"},94.32,"http://www.selleckchem.com/products/bradykinin.html","C50H73N15O11","Free Base","N/A","NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC(=O)NC(CC3=CC=CC=C3)C(=O)NC(CO)C(=O)N4CCCC4C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCCN=C(N)N)C(O)=O",{"v":-5.45,"d":"-5.450"},11,11,27]
["E0050","Seralutinib (GB002)","e11","L3800-42","in 10mM DMSO","N/A","N/A","Phase II","PDGFR","Protein Tyrosine Kinase","Seralutinib (PK10571, GB002) is a novel PDGFR kinase inhibitor with IC50s of 8 nM and 10 nM for PDGFRα and PDGFRβ in enzyme assays, respectively.",469.54,"1619931-27-9",{"v":94,"d":"94.00"},{"v":200.2,"d":"200.20"},"<1","N/A","http://www.selleckchem.com/products/seralutinib-pk10571.html","C27H27N5O3","Free Base","PK10571","COC1=C(OC)C=C(C=C1)C2=CN=CC(=N2)NC(C)C3=CC(=CC=C3)NC(=O)C4=CN=CC(=C4)C",{"v":3.87,"d":"3.870"},6,2,8]
["E0076","Simufilam dihydrochloride","g11","L3800-42","in 10mM DMSO","N/A","N/A","Phase III","Actin","Cytoskeletal Signaling","Simufilam (PTI-125) Dihydrochloride is a small molecule modulator that preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7nAChR/TLR4 associations and downstream pathologies.",332.27,"2480226-06-8",{"v":66,"d":"66.00"},198.63,{"v":66,"d":"66.00"},198.63,"http://www.selleckchem.com/products/simufilam-dihydrochloride.html","C15H23Cl2N3O","Dihydrochloride","PTI-125 dihydrochloride","Cl.Cl.CN1CCC2(CC1)NCC(=O)N2CC3=CC=CC=C3",{"v":1.86,"d":"1.860"},1,1,2]
["E0136","N-Nitrosodiethylamine","c2","L3800-43","in 10mM DMSO","N/A","N/A","Phase 2","Others","Others","N-Nitrosodiethylamine (N-Nitroso-diethylamine, NDEA, diethylnitrosamine, DEN) is DNA reactive after bioactivation and produces tumors in many animal species.",102.14,"55-18-5","N/A","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","http://www.selleckchem.com/products/n-nitrosodiethylamine.html","C4H10N2O","Free Base","N-Nitroso-diethylamine, NDEA, diethylnitrosamine, DEN","CCN(CC)N=O",{"v":0.79,"d":"0.790"},1,0,3]
["E0148","Linalyl Acetate","f2","L3800-43","in 10mM DMSO","N/A","EP10.5","N/A","Immunology & Inflammation related","Immunology & Inflammation","Linalyl Acetate (Bergamiol, Bergamol, Linalool acetate) is a naturally occurring phytochemical found in many flowers and spice plants. Linalyl Acetate is a potentially anti-inflammatory agent.",196.29,"115-95-7","N/A","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A","http://www.selleckchem.com/products/linalyl-acetate.html","C12H20O2","Free Base","Bergamiol, Bergamol, Linalool acetate","CC(C)=CCCC(C)(OC(C)=O)C=C",{"v":3.11,"d":"3.110"},2,0,6]
["E0156","Thioacetamide","a3","L3800-43","in 10mM DMSO","N/A","USP–NF 2021(Issue 2), EP10.5, IP2010","N/A","Others","Others","Thioacetamide (TAA) is a hepatotoxin frequently used for experimental purposes which produces centrilobular necrosis after a single dose administration.",75.13,"62-55-5",{"v":15,"d":"15.00"},199.65,{"v":15,"d":"15.00"},199.65,"http://www.selleckchem.com/products/thioacetamide.html","C2H5NS","Free Base","TAA","CC(N)=S",{"v":0.04,"d":"0.040"},0,1,0]
["E0160","Hexaminolevulinate hydrochloride","b3","L3800-43","in 10mM DMSO","FDA","N/A","Marketed","Others","Others","Hexaminolevulinate hydrochloride (5-Aminolevulinic acid hexyl ester hydrochloride) is a tumour photosensitizer.",251.75,"140898-91-5",{"v":50,"d":"50.00"},198.61,{"v":50,"d":"50.00"},198.61,"http://www.selleckchem.com/products/hexaminolevulinate-hydrochloride.html","C11H21NO3.ClH","Hydrochloride","5-Aminolevulinic acid hexyl ester hydrochloride","Cl.CCCCCCOC(=O)CCC(=O)CN",{"v":1.63,"d":"1.630"},3,1,10]
["E0169","Zinc acetate","e3","L3800-43","in 10mM DMSO","FDA, CFDA, PMDA, NDC","USP–NF 2021(Issue 2), EP10.5, Ph.Int_6th","Marketed","Others","Others","Zinc acetate induces the expression of enterocyte metallothionein.",183.48,"557-34-6",{"v":37,"d":"37.00"},201.66,{"v":37,"d":"37.00"},201.66,"http://www.selleckchem.com/products/zinc-acetate.html","C4H6O4Zn","Free Base","N/A","CC(=O)O[Zn]OC(C)=O",{"v":-0.23,"d":"-0.230"},4,0,4]
["E0177","Hydrocortisone sodium succinate","h3","L3800-43","in 10mM DMSO","FDA, CFDA, PMDA","JP18, USP–NF 2021(Issue 2), KP Ⅹ, Ph.Int_6th, IP2010","Marketed","Glucocorticoid Receptor,Interleukins","Immunology & Inflammation","Hydrocortisone sodium succinate (Hydrocortisone 21-hemisuccinate sodium salt) has significant inhibitory effects on the IL-6 bioactivity with IC50 of 6.7 μM. Hydrocortisone sodium succinate can bind to glucocorticoid receptor, initiating the transcription of anti-inflammatory and immunosuppressive mediators.",484.51,"125-04-2",{"v":97,"d":"97.00"},{"v":200.2,"d":"200.20"},{"v":97,"d":"97.00"},{"v":200.2,"d":"200.20"},"http://www.selleckchem.com/products/hydrocortisone-sodium-succinate.html","C25H33O8.Na","Sodium succinate","Hydrocortisone 21-hemisuccinate sodium salt","[Na+].CC12CCC(=O)C=C1CCC3C4CCC(O)(C(=O)COC(=O)CCC([O-])=O)C4(C)CC(O)C23",{"v":0.03,"d":"0.030"},4,1,7]
["E0361","Enclomiphene Citrate","d4","L3800-43","in 10mM DMSO","EMA","N/A","N/A","Estrogen/progestogen Receptor","Endocrinology & Hormones","Enclomiphene citrate is the trans isomer of clomiphene citrate and acts as a non-steroidal estrogen receptor antagonist.",598.08,"7599-79-3",{"v":100,"d":"100.00"},{"v":167.2,"d":"167.20"},"<1","N/A","http://www.selleckchem.com/products/enclomiphene-citrate.html","C26H28ClNO.C6H8O7","Citrate","N/A","CCN(CC)CCOC1=CC=C(C=C1)\\C(=C(\\Cl)C2=CC=CC=C2)C3=CC=CC=C3.OC(=O)CC(O)(CC(O)=O)C(O)=O",{"v":2.86,"d":"2.860"},4,0,14]
["E1003","Aminopterin","g4","L3800-43","in 10mM DMSO","N/A","N/A","Phase II","DHFR","Metabolism","Aminopterin (4-amino Folic Acid, 4-amino PGA, 4-Aminofolic acid, 4-Aminopteroylglutamic acid, Aminopteroylglutamic acid, APGA, NSC 739), a folic acid antagonist, is a competitive inhibitor of dihydrofolate reductase (DHFR) with Ki of 3.7 pM.",440.41,"54-62-6",{"v":88,"d":"88.00"},199.81,"<1","N/A","http://www.selleckchem.com/products/aminopterin.html","C19H20N8O5","Free Base","4-amino Folic Acid, 4-amino PGA, 4-Aminofolic acid, 4-Aminopteroylglutamic acid, Aminopteroylglutamic acid, APGA, NSC 739","NC1=NC(=C2N=C(CNC3=CC=C(C=C3)C(=O)NC(CCC(O)=O)C(O)=O)C=NC2=N1)N",{"v":-0.24,"d":"-0.240"},7,4,9]
["S0009","Asimadoline hydrochloride","c5","L3800-43","in 10mM DMSO","N/A","N/A","Phase II","Opioid Receptor","GPCR & G Protein","Asimadoline hydrochloride (EMD-61753 hydrochloride) is an orally active, selective and peripherally active κ-opioid agonist with IC50s of 5.6 nM (guinea pig) and 1.2 nM (human recombinant).",{"v":451,"d":"451.00"},"185951-07-9",{"v":90,"d":"90.00"},199.56,{"v":3,"d":"3.00"},6.65,"http://www.selleckchem.com/products/asimadoline.html","C27H30N2O2.ClH","hydrochloride","EMD-61753 hydrochloride","Cl.CN(C(CN1CCC(O)C1)C2=CC=CC=C2)C(=O)C(C3=CC=CC=C3)C4=CC=CC=C4",4.276,1,1,7]
["S0111","Taprenepag","f5","L3800-43","in 10mM DMSO","N/A","N/A","Phase II discontinued","Prostaglandin Receptor","Immunology & Inflammation","Taprenepag(CP-544326) is a potent and selective prostaglandin EP2 agonist with IC50s of 10 and 15 nM for human and rat EP2, respectively.",478.52,"752187-80-7",{"v":96,"d":"96.00"},200.62,"<1","N/A","http://www.selleckchem.com/products/cp544326.html","C24H22N4O5S","free base","CP-544326","OC(=O)COC1=CC=CC(=C1)CN(CC2=CC=C(C=C2)[N]3C=CC=N3)[S;v6](=O)(=O)C4=CN=CC=C4",2.655,6,0,10]
["S0312","Rimeporide","a6","L3800-43","in 10mM DMSO","N/A","N/A","Phase 1","Sodium Channel","Transmembrane Transporters","Rimeporide(EMD-87580) is a sodium hydrogen exchanger (NHE-1) inhibitor indicated for patients with Duchenne muscular dystrophy.",333.38,"187870-78-6",{"v":67,"d":"67.00"},200.97,"<1","N/A","http://www.selleckchem.com/products/rimeporide.html","C11H15N3O5S2","free base","EMD-87580","CC1=CC(=C(C=C1C(=O)NC(N)=N)[S](C)(=O)=O)[S](C)(=O)=O",0.204,5,2,4]
["S0318","Ansofaxine hydrochloride","b6","L3800-43","in 10mM DMSO","N/A","N/A","Preregistration","5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Ansofaxine hydrochloride (LY03005, LPM570065), a triple reuptake inhibitor, inhibits serotonin, dopamine and norepinephrine reuptake with IC50 values of 723, 491 and 763 nM, respectively.",417.97,"916918-84-8",{"v":84,"d":"84.00"},200.97,{"v":3,"d":"3.00"},7.18,"http://www.selleckchem.com/products/ansofaxine-hydrochloride.html","C24H31NO3.ClH","hydrochloride","LY03005, LPM570065","Cl.CN(C)CC(C1=CC=C(OC(=O)C2=CC=C(C)C=C2)C=C1)C3(O)CCCCC3",5.338,2,0,7]
["S0535","FK962","f6","L3800-43","in 10mM DMSO","N/A","N/A","Phase II discontinued","Calcium Channel,SSTR","Transmembrane Transporters","FK962, a derivative of FK960 with putative anti-dementia properties, significantly enhances high K+-evoked somatostatin release from rat hippocampal slices at 1-1000 nM, also significantly reduces somatostatin-induced inhibition of Ca2+ channels at 1-100 nM in single rat hippocampal neurons.",{"v":264.3,"d":"264.30"},"283167-06-6",{"v":53,"d":"53.00"},200.53,{"v":2,"d":"2.00"},7.57,"http://www.selleckchem.com/products/fk962.html","C14H17FN2O2","free base","N/A","CC(=O)N1CCC(CC1)NC(=O)C2=CC=C(F)C=C2",0.613,2,1,2]
["S1239","TAK-960","b7","L3800-43","in 10mM DMSO","N/A","N/A","Phase 1","PLK","Cell Cycle","TAK-960 is a novel, investigational, orally bioavailable, potent, and selective PLK1 inhibitor that has shown activity in several tumor cell lines, including those that express multidrug-resistant protein 1 (MDR1).",{"v":561.6,"d":"561.60"},"1137868-52-0",{"v":13,"d":"13.00"},23.15,"<1","N/A","http://www.selleckchem.com/products/tak-960.html","C27H34F3N7O3","free base","N/A","COC1=C(NC2=NC=C3N(C)C(=O)C(F)(F)CN(C4CCCC4)C3=N2)C=C(F)C(=C1)C(=O)NC5CCN(C)CC5",3.451,5,2,6]
["S2174","Hydroxyflutamide (Hydroxyniphtholide)","e7","L3800-43","in 10mM DMSO","N/A","N/A","Phase II","Adrenergic Receptor","Endocrinology & Hormones","Hydroxyflutamide (SCH-16423, Hydroxyniphtholide) is an androgen receptor (AR) antagonist and possesses an IC50 of 0.7 μM for the androgen receptor.",292.21,"52806-53-8",{"v":58,"d":"58.00"},198.49,"<1","N/A","http://www.selleckchem.com/products/hydroxyflutamide-sch-16423-hydroxyniphtholide.html","C11H11F3N2O4","free base","Hydroxy-flutamide, SCH-16423","CC(C)(O)C(=O)NC1=CC=C(C(=C1)C(F)(F)F)[N+]([O-])=O",{"v":1.91,"d":"1.910"},1,1,4]
["S3374","Verubulin hydrochloride","h7","L3800-43","in 10mM DMSO","N/A","N/A","Phase II","Microtubule Associated","Cytoskeletal Signaling","Verubulin hydrochloride(MPC 6827 hydrochloride) is a microtubule destabilizer and vascular disrupting agent that achieve high brain concentration relative to plasma in animals.",{"v":315.8,"d":"315.80"},"917369-31-4",{"v":56,"d":"56.00"},200.47,{"v":56,"d":"56.00"},200.47,"http://www.selleckchem.com/products/verubulin-hydrochloride.html","C17H18ClN3O","hydrochloride","MPC 6827 hydrochloride","Cl.COC1=CC=C(C=C1)N(C)C2=C3C=CC=CC3=NC(=N2)C",4.004,3,0,3]
["S3561","DLinDMA","d8","L3800-43","in 10mM DMSO","DMF","N/A","N/A","Others","Others","DLinDMA (1,2-dilinoleyloxy-N,N-dimethyl-3-aminopropane) is a key component to facilitate endosomal escape through membrane fusion between the SNALP and the endosomal membranes.",616.06,"871258-12-7","The physical form of the compound is liquid, which can be dissolved in any proportion","The physical form of the compound is liquid, which can be dissolved in any proportion","N/A","N/A","http://www.selleckchem.com/products/dlindma.html","C41H77NO2","free base","N/A","CCCCC/C=C\\C\\C=C/CCCCCCCCOCC(CN(C)C)OCCCCCCCC\\C=C/C/C=C\\CCCCC",16.675,2,0,35]
["S6458","Isavuconazonium sulfate","g8","L3800-43","in 10mM DMSO","FDA,EMA,DMF","N/A","Marketed","Anti-infection","Microbiology","Isavuconazonium sulfate (BAL8557-002), the prodrug of the active triazole Isavuconazole, is an orally active antifungal agent, using for invasive aspergillosis and mucormycosis.",814.84,"946075-13-4",{"v":100,"d":"100.00"},122.72,{"v":100,"d":"100.00"},122.72,"http://www.selleckchem.com/products/isavuconazonium-sulfate.html","C35H35F2N8O5S.HO4S","sulfate","BAL8557-002","CNCC(=O)OCC1=C(N=CC=C1)N(C)C(=O)OC(C)[N+]2=C[N](CC(O)(C(C)C3=NC(=CS3)C4=CC=C(C=C4)C#N)C5=C(F)C=CC(=C5)F)N=C2.O[S]([O-])(=O)=O",2.963,7,1,15]
["S9893","Venadaparib(IDX-1197)","b9","L3800-43","in 10mM DMSO","N/A","N/A","Phase I/II","PARP","DNA Damage/DNA Repair","Venadaparib (IDX-1197), a potent PARP1/2 inhibitor with IC50 values of 1.4 nM and 1.0 nM respectively, prevents the repair of DNA single-strand breaks (SSB) and promotes the conversion of SSB to double-stranded breaks (DSB), which ultimately leads to synthetic lethality in cancer cells.",406.45,"1681017-83-3",{"v":81,"d":"81.00"},199.29,"<1","N/A","http://www.selleckchem.com/products/venadaparib-idx-1197.html","C23H23FN4O2","free base","N/A","FC1=C(C=C(CC2=NNC(=O)C3=CC=CC=C23)C=C1)C(=O)N4CC(CNC5CC5)C4",{"v":2.12,"d":"2.120"},3,2,6]
["S9934","KA2507","c9","L3800-43","in 10mM DMSO","N/A","N/A","Phase 2","HDAC","Epigenetics","KA2507, a potent, orally active and selective HDAC6 inhibitor with IC50 of 2.5 nM, shows antitumor activities and immune modulatory effects in preclinical models.",322.32,"1636894-46-6",{"v":64,"d":"64.00"},198.56,{"v":64,"d":"64.00"},198.56,"http://www.selleckchem.com/products/ka2507.html","C16H14N6O2","free base","N/A","ONC(=O)C1=CC=C(CN(C2=NC=CN=C2)C3=NC=CN=C3)C=C1",{"v":0.66,"d":"0.660"},5,1,5]
["E0097","Mericitabine","g9","L3800-43","in 10mM DMSO","N/A","N/A","Phase II discontinued","HCV Protease","Proteases","Mericitabine (RG 7128, R-7128, PSI 6130 diisobutyrate) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication.",399.41,"940908-79-2",{"v":80,"d":"80.00"},{"v":200.3,"d":"200.30"},"<1","N/A","http://www.selleckchem.com/products/mericitabine.html","C18H26FN3O6","free base","RG 7128, R-7128, PSI 6130 diisobutyrate","CC(C)C(=O)OCC1OC(N2C=CC(=NC2=O)N)C(C)(F)C1OC(=O)C(C)C",1.766,7,1,8]
["E0117","Deferitrin","a10","L3800-43","in 10mM DMSO","N/A","N/A","Phase I/II","Others","Others","Deferitrin(GT-56-252) is a novel oral iron chelator for the treatment of chronic iron overload due to blood transfusion therapy.",253.28,"239101-33-8",{"v":51,"d":"51.00"},201.36,"<1","N/A","http://www.selleckchem.com/products/deferitrin.html","C11H11NO4S","free base","GT-56-252","CC1(CSC(=N1)C2=CC=C(O)C=C2O)C(O)=O",1.767,2,2,2]
["E0191","DL-α-tocopherol acetate","d10","L3800-43","in 10mM DMSO","CFDA","EP10.5","Marketed","Others","Others","DL-α-Tocopherol acetate (DL-Alpha-tocopherol acetate , Vitamin E acetate), a vitamin E derivative, is used as a vitamin E supplement in poultry feeds.",472.74,"52225-20-4","The physical form of the compound is liquid, which can be dissolved in any proportion","The physical form of the compound is liquid, which can be dissolved in any proportion","N/A","N/A","http://www.selleckchem.com/products/dl-alpha-tocopherol-acetate.html","C31H52O3","free base","DL-Alpha-tocopherol acetate, Vitamin E acetate","CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=C(C)C(=C(C)C(=C2O1)C)OC(C)=O",{"v":10.45,"d":"10.450"},3,0,14]
["E0376","DPPE fumarate","g10","L3800-43","in 10mM DMSO","N/A","N/A","Phase III discontinued","Others","Others","DPPE fumarate (Tesmilifene fumarate) is a novel potentiator of chemotherapy, which is found to potentiate a wide range of cytotoxics and to protect normal cells.",399.48,"1185241-83-1",{"v":80,"d":"80.00"},200.26,{"v":80,"d":"80.00"},200.26,"http://www.selleckchem.com/products/dppe-fumarate.html","C19H25NO.C4H4O4","fumarate","Tesmilifene fumarate","CCN(CC)CCOC1=CC=C(CC2=CC=CC=C2)C=C1.OC(=O)\\C=C\\C(O)=O",2.362,3,0,10]
["E0501","Senicapoc (ICA-17043)","c11","L3800-43","in 10mM DMSO","N/A","N/A","Phase III discontinued","Potassium Channel","Transmembrane Transporters","Senicapoc (ICA-17043) is a Gardos channel(Ca2+-activated K+ channel; KCa3.1) blocker with an IC50 of 11 nM and produces dose-dependent increases in hemoglobin and decreases in markers of hemolysis. Senicapoc blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM.",323.34,"289656-45-7",{"v":65,"d":"65.00"},201.03,"<1","N/A","http://www.selleckchem.com/products/senicapoc-ica-17043.html","C20H15F2NO","free base","N/A","NC(=O)C(C1=CC=CC=C1)(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3",4.221,1,1,4]
["E0528","Flecainide","g11","L3800-43","in 10mM DMSO","FDA,PMDA,NDC,DMF","USP43-NF38,EP8.8,JP16","Marketed","Others","Neuronal Signaling","Flecainide is a common medication used to help restore and maintain sinus rhythm in patients with atrial fibrillation.",414.34,"54143-55-4",{"v":83,"d":"83.00"},200.32,"<1","N/A","http://www.selleckchem.com/products/flecainide.html","C17H20F6N2O3","free base","N/A","FC(F)(F)COC1=CC=C(OCC(F)(F)F)C(=C1)C(=O)NCC2CCCCN2",3.568,3,2,9]
["E0609","Methyl methanesulfonate","b2","L3800-44","in 10mM DMSO","N/A","EP10.8","N/A","DNA alkylator","DNA Damage/DNA Repair","Methyl methanesulfonate (MMS), a DNA alkylating agent, modifies both guanine (to 7-methylguanine) and adenine (to 3-methlyladenine) to cause base mispairing and replication blocks, respectively.",110.13,"66-27-3","The physical form of the compound is liquid, which can be dissolved in any proportion","The physical form of the compound is liquid, which can be dissolved in any proportion","N/A","N/A","http://www.selleckchem.com/products/methyl-methanesulfonate.html","C2H6O3S","free base","MMS","CO[S](C)(=O)=O",-0.375,1,0,1]
["E0617","Lodenafil","c2","L3800-44","in 10mM DMSO","N/A","N/A","Phase IV","PDE","Metabolism","Lodenafil (Hydroxyhomosildenafil) is a potent phosphodiesterase type 5 (PDE5)  inhibitor for the treatment of erectile dysfunction (ED).",{"v":504.6,"d":"504.60"},"139755-85-4",{"v":100,"d":"100.00"},198.18,"<1","N/A","http://www.selleckchem.com/products/lodenafil.html","C23H32N6O5S","free base","Hydroxyhomosildenafil","CCCC1=N[N](C)C2=C1NC(=NC2=O)C3=C(OCC)C=CC(=C3)[S;v6](=O)(=O)N4CCN(CCO)CC4",1.707,6,2,9]
["E0650","γ-Terpinene","f2","L3800-44","in 10mM DMSO","N/A","EP10.8","N/A","Antioxidant","Apoptosis","γ-Terpinene (γ-TPN), a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly.,",136.23,"99-85-4","The physical form of the compound is liquid, which can be dissolved in any proportion","The physical form of the compound is liquid, which can be dissolved in any proportion","N/A","N/A","http://www.selleckchem.com/products/gamma-terpinen.html","C10H16","free base","γ-TPN","CC(C)C1=CCC(=CC1)C",3.448,0,0,1]
["E0758","Silydianin","b3","L3800-44","in 10mM DMSO","N/A","N/A","Phase II","phosphatase","Metabolism","Silydianin is an active constituent of Silybium marianum, with exhibit anti-collagenase, antitumor and anti-elastase activities.",482.44,"29782-68-1",{"v":96,"d":"96.00"},198.99,"<1","N/A","http://www.selleckchem.com/products/silydianin.html","C25H22O10","free base","N/A","COC1=C(O)C=CC(=C1)C2C3COC4(O)C3C(=CC2C4=O)C5OC6=CC(=CC(=C6C(=O)C5O)O)O",1.059,5,4,3]
["E0809","Timapiprant Sodium","e3","L3800-44","in 10mM DMSO","N/A","N/A","Phase III","Prostaglandin Receptor","GPCR & G Protein","Timapiprant sodium (OC000459 sodium), a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known as CRTH2) antagonist, potently displaces [3H]PGD2 from human recombinant DP2, rat recombinant DP2, and human native DP2 with Ki values of 13, 3 and 4 nM, respectively.",371.36,"950688-14-9",{"v":74,"d":"74.00"},199.27,"<1","N/A","http://www.selleckchem.com/products/timapiprant-sodium.html","C21H17FN2O2.Na","Sodium salt","OC000459 sodium","[NaH].CC1=C(CC2=NC3=C(C=CC=C3)C=C2)C4=CC(=CC=C4[N]1CC(O)=O)F",4.329,2,0,4]
["E0815","Rilpivirine Hydrochloride","h3","L3800-44","in 10mM DMSO","FDA,EMA,PMDA,NDC,DMF","N/A","Marketed","Reverse Transcriptase","Microbiology","Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.",402.88,"700361-47-3",{"v":81,"d":"81.00"},201.05,"<1","N/A","http://www.selleckchem.com/products/rilpivirine-hydrochloride.html","C22H18N6.ClH","hydrochloride","TMC278","Cl.CC1=C(NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C(=CC(=C1)\\C=C\\C#N)C",5.791,2,2,5]
["E0828","Mitonafide","d4","L3800-44","in 10mM DMSO","N/A","N/A","Phase 2","Bacterial","Microbiology","Mitonafide inhibits the activity of Mycobacterium tuberculosis NAD+ dependent DNA ligase A at concentrations of 50 µM.",313.31,"54824-17-8",{"v":32,"d":"32.00"},102.14,"<1","N/A","http://www.selleckchem.com/products/mitonafide.html","C16H15N3O4","free base","N/A","CN(C)CCN1C(=O)C2=CC=CC3=C2C(=CC(=C3)[N;v5](=O)=O)C1=O",1.803,2,0,4]
["E0960","RO5186582","g4","L3800-44","in 10mM DMSO","N/A","N/A","Phase II discontinued","GABA Receptor","Transmembrane Transporters","RO5186582 (Basmisanil, RG1662) is a highly selective GABAAα5 negative allosteric modulator.",445.47,"1159600-41-5",{"v":89,"d":"89.00"},199.79,"<1","N/A","http://www.selleckchem.com/products/ro5186582.html","C21H20FN3O5S","free base","Basmisanil, RG1662","CC1=C(COC2=CC=C(C=N2)C(=O)N3CC[S;v6](=O)(=O)CC3)C(=NO1)C4=CC=C(F)C=C4",2.368,7,0,5]
["E1014","Upamostat (WX-671)","h4","L3800-44","in 10mM DMSO","N/A","N/A","Phase II/III","Serine Protease","Proteases","Upamostat (WX-671), a novel serine protease urokinase (uPA) inhibitor by inhibiting the urokinase-type plasminogen activator (uPA) system.",629.81,"590368-25-5",{"v":100,"d":"100.00"},158.78,"<1","N/A","http://www.selleckchem.com/products/upamostat-wx-671.html","C32H47N5O6S","free base","WX-671","CCOC(=O)N1CCN(CC1)C(=O)C(CC2=CC(=CC=C2)C(=N)NO)N[S](=O)(=O)C3=C(C=C(C=C3C(C)C)C(C)C)C(C)C",4.907,5,2,13]
["E1107","CTB","c5","L3800-44","in 10mM DMSO","N/A","N/A","Phase 4","Histone Acetyltransferase","Epigenetics","CTB is a p300 activator and the lowest docked energy for CTB and p300 is 7.72 kcal/mol.",343.73,"451491-47-7",{"v":69,"d":"69.00"},200.74,"<1","N/A","http://www.selleckchem.com/products/ctb.html","C16H13ClF3NO2","free base","N/A","CCOC1=CC=CC=C1C(=O)NC2=CC=C(Cl)C(=C2)C(F)(F)F",4.553,2,1,5]
["E1178","FHD-286","f5","L3800-44","in 10mM DMSO","N/A","N/A","Phase 1","ATPase","Transmembrane Transporters","FHD-286 is a BRG1/BRM ATPase inhibitor for the treatment of BAF-related disorders such as acute myeloid leukemia.",562.66,"2671128-05-3",{"v":100,"d":"100.00"},177.73,"<1","N/A","http://www.selleckchem.com/products/fhd-286.html","C24H30N6O6S2","free base","N/A","COCC(NC(=O)C1=C[N](C=C1)[S;v6](C)(=O)=O)C(=O)NC2=NC(=CS2)C3=CC=CC(=N3)N4CC(C)OC(C)C4",1.919,8,2,9]
["E2355","Dotinurad","b6","L3800-44","in 10mM DMSO","PMDA","N/A","Marketed","OAT","Transmembrane Transporters","Dotinurad (FYU-981), a selective urate reabsorption inhibitor (SURI), potently inhibits urate transporter 1 (URAT1) with IC50 of 37.2 nM.",{"v":358.2,"d":"358.20"},"1285572-51-1",{"v":72,"d":"72.00"},201.01,"<1","N/A","http://www.selleckchem.com/products/dotinurad.html","C14H9Cl2NO4S","free base","FYU-981","OC1=C(Cl)C=C(C=C1Cl)C(=O)N2C[S;v6](=O)(=O)C3=CC=CC=C23",3.234,3,1,1]
["E2385","SAR407899 hydrochloride","e6","L3800-44","in 10mM DMSO","N/A","N/A","Phase II discontinued","Rho","Cell Cycle","SAR407899 hydrochloride is a selective, potent and ATP-competitive Rho kinase (ROCK) inhibitor, with an IC50 of 135 nM for ROCK-2, and Ki values of 36 and 41 nM for human and rat ROCK-2, respectively.",280.75,"923262-96-8",{"v":28,"d":"28.00"},99.73,{"v":56,"d":"56.00"},199.47,"http://www.selleckchem.com/products/sar407899-hydrochloride.html","C14H16N2O2.ClH","hydrochloride","N/A","Cl.O=C1NC=CC2=C1C=CC(=C2)OC3CCNCC3",0.667,2,2,2]
["E2516","Doxorubicin","h6","L3800-44","in 10mM DMSO","FDA,CFDA,EMA,HMA,NDC,DMF","USP40-NF35,EP9.1,JP18","Marketed","Topoisomerase","DNA Damage/DNA Repair","Adriamycin (Doxorubicin, Hydroxydaunorubicin), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent, inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DNA replication, and induces apoptosis, also inhibits human DNA topoisomerase I with an IC50 of 0.8 μM.",543.52,"23214-92-8",{"v":100,"d":"100.00"},183.99,{"v":50,"d":"50.00"},91.99,"http://www.selleckchem.com/products/doxorubicin.html","C27H29NO11","free base","Adriamycin,Hydroxydaunorubicin","COC1=C2C(=O)C3=C(C(=C4CC(O)(CC(OC5CC(N)C(O)C(C)O5)C4=C3O)C(=O)CO)O)C(=O)C2=CC=C1",-0.044,6,5,5]
["E2683","Ursodeoxycholic acid sodium","c7","L3800-44","in 10mM DMSO","CFDA,PMDA,DMF","USP38-NF33,JP16,EP8.8","Marketed","Others","Others","Ursodeoxycholic acid sodium is a sodium salt of a naturally occurring bile acid that is used to treat a variety of hepatic and gastrointestinal diseases.",414.55,"2898-95-5",{"v":83,"d":"83.00"},200.22,{"v":83,"d":"83.00"},200.22,"http://www.selleckchem.com/products/ursodeoxycholic-acid-sodium.html","C24H40O4.Na","Sodium salt","N/A","[Na+].CC(CCC([O-])=O)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C",{"v":2.54,"d":"2.540"},0,2,4]
["E2838","M7583","f7","L3800-44","in 10mM DMSO","N/A","N/A","Phase II","BTK","Angiogenesis","M7583 is a potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor with IC50 and Ki of 1.5 nM and 11.9 nM, respectively.",447.51,"1415823-49-2",{"v":90,"d":"90.00"},201.11,"<1","N/A","http://www.selleckchem.com/products/tl-895.html","C25H26FN5O2","free base","N/A","NC1=C(C(=NC=N1)NCC2(F)CCN(CC2)C(=O)C=C)C3=CC=C(OC4=CC=CC=C4)C=C3",3.594,4,2,7]
["P1008","Carbetocin Acetate","g7","L3800-44","in 10mM DMSO","CFDA","ChP37776","Marketed","Oxytocin receptor","Endocrinology & Hormones","Carbetocin Acetate is a long-acting oxytocin-analogue and a potent agonist of the oxytocin receptor (OXTR), with improved in vivo stability over oxytocin.",988.16,"37025-55-1",{"v":100,"d":"100.00"},{"v":101.2,"d":"101.20"},{"v":100,"d":"100.00"},{"v":101.2,"d":"101.20"},"http://www.selleckchem.com/peptide/carbetocin-acetate.html","C45H69N11O12S","Acetate","N/A","CCC(C)C1NC(=O)C(CC2=CC=C(OC)C=C2)NC(=O)CCCSCC(NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC1=O)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(N)=O.CC(O)=O",-1.699,13,10,18]
["P1114","Dasiglucagon","b8","L3800-44","in 10mM DMSO","FDA,NDC","N/A","Marketed","Others","Metabolism","Dasiglucagon, a stable peptide analog of human glucagon, is a fast and effective treatment option for severe hypoglycemia.",3381.62,"1544300-84-6",{"v":100,"d":"100.00"},29.57,{"v":100,"d":"100.00"},29.57,"http://www.selleckchem.com/products/dasiglucagon.html","C152H222N38O50","free base","N/A","CC(C)CC(NC(=O)C(CC1=C[NH]C2=CC=CC=C12)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C)NC(=O)C(CCCNC(N)=N)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C(CC(O)=O)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=C(O)C=C4)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC5=CC=C(O)C=C5)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(NC(=O)C(CC6=CC=CC=C6)NC(=O)C(NC(=O)CNC(=O)C(CCC(N)=O)NC(=O)C(CO)NC(=O)C(N)CC7=CN=C[NH]7)C(C)O)C(C)O)C(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CO)C(=O)NC(C(C)O)C(O)=O",-19.686,36,45,110]
["P1218","Disitertide(P144)","f8","L3800-44","in 10mM DMSO","N/A","N/A","Phase II","PI3K,TGF-beta/Smad","TGF-beta/Smad","Disitertide (P144) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor, is also a PI3K inhibitor and an apoptosis inducer.",1580.83,"272105-42-7",{"v":25,"d":"25.00"},15.81,"<1","N/A","http://www.selleckchem.com/products/disitertide.html","C68H109N17O22S2","free base","N/A","CCC(C)C(NC(=O)C(NC(=O)C(CO)NC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(N)C(C)O)C(C)CC)C(=O)NC(CC1=C[NH]C2=CC=CC=C12)C(=O)NC(C)C(=O)NC(CCSC)C(=O)NC(CCSC)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(O)=O",-7.833,17,20,51]
["S6918","Oleandrin (PBI-05204)","b9","L3800-44","in 10mM DMSO","N/A","N/A","Phase 2","ATPase","Transmembrane Transporters","Oleandrin (PBI-05204, Foliandrin, Neriolin, Neriostene, Folinerin, Corrigen, Neriol) is an inhibitor of Na+/K+-ATPase with IC50 of 0.62 μM. Oleandrin induces apoptosis and reduces migration of human glioma cells in vitro.",576.72,"465-16-7",{"v":100,"d":"100.00"},173.39,"<1","N/A","http://www.selleckchem.com/products/oleandrin-pbi-05204.html","C32H48O9","free base","Foliandrin, Neriolin, Neriostene, Folinerin, Corrigen, Neriol","COC1CC(OC(C)C1O)OC2CCC3(C)C(CCC4C3CCC5(C)C(C(CC45O)OC(C)=O)C6=CC(=O)OC6)C2",{"v":2.78,"d":"2.780"},7,1,6]
["S7108","Encorafenib (LGX818)","e9","L3800-44","in 10mM DMSO","FDA,EMA,PMDA,DMF","NA","Marketed","Raf","MAPK","Encorafenib (LGX818) is a highly potent RAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing B-RAF(V600E) with EC50 of 4 nM. Phase 3.",540.01,"1269440-17-6",{"v":100,"d":"100.00"},185.18,"<1","N/A","http://www.selleckchem.com/products/lgx818.html","C22 H27 Cl F N7 O4 S","free base","N/A","COC(=O)NC(C)CNC1=NC=CC(=N1)C2=C[N](N=C2C3=C(F)C(=CC(=C3)Cl)N[S;v6](C)(=O)=O)C(C)C",3.645,7,3,10]
["S8381","BMS-986142","h9","L3800-44","in 10mM DMSO","NA","NA","Phase II","BTK","Protein Tyrosine Kinase","BMS-986142 is a potent and highly selective reversible small molecule inhibitor of BTK with an IC50 of 0.5 nM. In a panel of 384 kinases, only five kinases were inhibited by BMS-986142 with less than 100-fold selectivity for BTK (TEC, ITK, BLK, TXK and BMX).",{"v":572.6,"d":"572.60"},"1643368-58-4",{"v":100,"d":"100.00"},174.64,"<1","N/A","http://www.selleckchem.com/products/bms-986142.html","C32H30F2N4O4","free base","N/A","CN1C(=O)N(C(=O)C2=CC=CC(=C12)F)C3=CC=CC(=C3C)C4=C5C6=C(CC(CC6)C(C)(C)O)[NH]C5=C(C=C4F)C(N)=O",5.323,3,2,4]
["S8719","AZD4573","d10","L3800-44","in 10mM DMSO","NA","NA","Phase I/II","CDK","Cell Cycle","AZD4573 is a potent inhibitor of CDK9 (IC50 of <0.004 μM) with fast-off binding kinetics (t1/2 = 16 min) and high selectivity versus other kinases, including other CDK family kinases.",429.94,"2057509-72-3",{"v":86,"d":"86.00"},200.03,"<1","N/A","http://www.selleckchem.com/products/azd4573.html","C22H28ClN5O2","free base","N/A","CC(=O)NC1CCCC(C1)C(=O)NC2=CC(=C(Cl)C=N2)C3=C4CC(C)(C)C[N]4N=C3",2.786,4,2,4]
["S8879","Deucravacitinib (BMS-986165)","g10","L3800-44","in 10mM DMSO","NA","NA","Preregistration","IFN,Interleukins,JAK","Protein Tyrosine Kinase","Deucravacitinib (BMS-986165) is a highly potent and selective allosteric inhibitor of Tyk2 with a Ki value of 0.02 nM for binding to the Tyk2 pseudokinase domain. It is highly selective against a panel of 265 kinases and pseudokinases.",425.46,"1609392-27-9",{"v":29,"d":"29.00"},68.16,"<1","N/A","http://www.selleckchem.com/products/bms-986165.html","C20H19D3N8O3","free base","N/A","C(NC(=O)C1=C(NC2=CC=CC(=C2OC)C3=N[N](C)C=N3)C=C(NC(=O)C4CC4)N=N1)([2H])([2H])[2H]",1.385,7,3,8]
["S8983","MAK683","h10","L3800-44","in 10mM DMSO","NA","NA","Phase I/II","Histone Methyltransferase","Epigenetics","MAK683 (EED inhibitor-1, example 2) is an inhibitor of embryonic ectoderm development (EED). MAK683 exhibits IC50 of 59 nM, 89 nM and 26 nM in EED Alphascreen binding, LC-MS and ELISA assay, respectively.",376.39,"1951408-58-4",{"v":20,"d":"20.00"},53.14,"<1","N/A","http://www.selleckchem.com/products/mak683.html","C20H17FN6O","free base","EED inhibitor-1","CC1=C(C=CC=N1)C2=CN=C(NCC3=C(F)C=CC4=C3CCO4)[N]5C=NN=C25",2.824,5,1,4]
["S0037","Nidufexor (LMB-763)","c11","L3800-44","in 10mM DMSO","N/A","N/A","Phase II","FXR","Metabolism","Nidufexor (LMB763) is an agonist of farnesoid X receptor (FXR).",487.93,"1773489-72-7",{"v":100,"d":"100.00"},204.95,"<1","N/A","http://www.selleckchem.com/products/nidufexor-lmb-763.html","C27H22ClN3O4","Free base","N/A","C[N]1N=C(C(=O)N(CC2=CC=CC=C2)CC3=CC=C(C=C3)C(O)=O)C4=C1C5=C(OC4)C=CC(=C5)Cl",{"v":5.33,"d":"5.330"},4,0,6]
["S0164","AZD-7325","f11","L3800-44","in 10mM DMSO","N/A","N/A","Phase II","GABA Receptor","Neuronal Signaling","AZD7325 is a potent and orally active partial selective Positive allosteric modulator (PAM) of GABAAα2 and Aα3 receptor with Ki=0.3 and 1.3 nM, respectively, and has less antagonistic efficacy at the Aα1 and Aα5 receptor subtypes.",354.38,"942437-37-8",{"v":71,"d":"71.00"},200.35,"<1","N/A","http://www.selleckchem.com/products/azd-7325.html","C19H19FN4O2","Free base","N/A","CCCNC(=O)C1=C(N)C2=C(N=N1)C(=CC=C2)C3=C(OC)C=CC=C3F",3.018,4,2,5]
["S0491","Manogepix (E1210)","b2","L3800-45","in 10mM DMSO","N/A","N/A","Phase 1","Fungal","Microbiology","Manogepix (E1210, MGX, APX001A) is a broad-spectrum and orally active antifungal agent that inhibits Gwt1/Gwt1p (GPI-anchored wall transfer protein 1), a protein that plays an important role in fungal cell wall integrity.",358.39,"936339-60-5",{"v":72,"d":"72.00"},{"v":200.9,"d":"200.90"},"<1","N/A","http://www.selleckchem.com/products/e1210.html","C21H18N4O2","Free base","MGX, APX001A","NC1=C(C=CC=N1)C2=CC(=NO2)CC3=CC=C(COC4=CC=CC=N4)C=C3",3.673,5,1,6]
["S0803","Danicopan (ACH-4471)","e2","L3800-45","in 10mM DMSO","N/A","N/A","Phase III","Complement System","Immunology & Inflammation","Danicopan (ACH-4471, ACH-0144471, ACH-CFDIS, ALXN 2040) is a potent, selective and orally active inhibitor of factor D with Kd of 0.54 nM for human Factor D. Danicopan inhibits alternative pathway of complement (APC) activity, and has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).",580.41,"1903768-17-1",{"v":100,"d":"100.00"},172.29,"<1","N/A","http://www.selleckchem.com/products/danicopan.html","C26H23BrFN7O3","Free base","ACH-0144471, ACH-CFDIS, ALXN 2040","CC(=O)C1=N[N](CC(=O)N2CC(F)CC2C(=O)NC3=NC(=CC=C3)Br)C4=C1C=C(C=C4)C5=CN=C(C)N=C5",2.262,7,1,6]
["S0878","AT-001","a3","L3800-45","in 10mM DMSO","N/A","N/A","Phase III","Aldose Reductase","Metabolism","AT-001 (Aldose reductase-IN-1) is an aldose reductase inhibitor with IC50 of 28.9 pM.",421.35,"1355612-71-3",{"v":84,"d":"84.00"},199.36,"<1","N/A","http://www.selleckchem.com/products/at-001.html","C17H10F3N5O3S","Free base","Aldose reductase-IN-1","OC(=O)CC1=NN(CC2=NC3=CC(=CC=C3S2)C(F)(F)F)C(=O)C4=NC=CN=C14",2.208,6,0,5]
["S1575","RO4929097","d3","L3800-45","in 10mM DMSO","N/A","N/A","Phase 2","Beta Amyloid,Notch,Secretase","Proteases","RO4929097 (RG-4733) is a γ secretase inhibitor with IC50 of 4 nM in a cell-free assay, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively. Phase 2.",{"v":469.4,"d":"469.40"},"847925-91-1",{"v":93,"d":"93.00"},198.13,"<1","N/A","http://www.selleckchem.com/products/RO4929097.html","C22H20F5N3O3","Free base","RG-4733","CC(C)(C(=O)NCC(F)(F)C(F)(F)F)C(=O)NC1C(=O)NC2=CC=CC=C2C3=C1C=CC=C3",3.184,3,3,6]
["S2345","Podophyllotoxin (Podofilox)","g3","L3800-45","in 10mM DMSO","FDA,CFDA","EP10.8","Marketed","5-alpha Reductase","Angiogenesis","Podophyllotoxin (Condylox,Podofilox) is a lignan (lignans) found in podophyllin resin from the roots of podophyllum plants.",414.41,"518-28-5",{"v":83,"d":"83.00"},200.28,"<1","N/A","http://www.selleckchem.com/products/Podophyllotoxin(Podofilox).html","C22H22O8","Free base","Condylox,Podofilox","COC1=C(OC)C(=CC(=C1)C2C3C(COC3=O)C(O)C4=CC5=C(OCO5)C=C24)OC",2.111,7,1,4]
["S2653","9-amino-CPT (9-Aminocamptothecin)","h3","L3800-45","in 10mM DMSO","N/A","N/A","Phase 2","Topoisomerase","DNA Damage/DNA Repair","9-amino-CPT (9-Aminocamptothecin, 9-AC, Aminocamptothecin, 9-amino-20(S)-camptothecin) is a Topoisomerase I inhibitor with potent anticancer activities. 9-amino-CPT (9-Aminocamptothecin) is an active, water-insoluble derivative of camptothecin.",363.37,"91421-43-1",{"v":25,"d":"25.00"},{"v":68.8,"d":"68.80"},"<1","N/A","http://www.selleckchem.com/products/9-amino-cpt.html","C20H17N3O4","Free base","9-AC, Aminocamptothecin, 9-amino-20(S)-camptothecin","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC=C(N)C5=C4)C2=O",0.999,4,1,1]
["S2975","CarboxyaMidotriazole orotate","c4","L3800-45","in 10mM DMSO","N/A","N/A","Phase II","Calcium Channel","Transmembrane Transporters","Carboxyamidotriazole Orotate (L-651582 Orotate) is the orotate salt form of Carboxyamidotriazole (CAI), an orally bioavailable signal transduction inhibitor. Carboxyamidotriazole Orotate is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole Orotate inhibits angiogenesis, tumor growth, invasion, and metastasis.",580.76,"187739-60-2",{"v":25,"d":"25.00"},43.05,"<1","N/A","http://www.selleckchem.com/products/carboxyamidotriazole-orotate.html","C22H16Cl3N7O6","Orotate","L-651582 Orotate, CAI Orotate","NC(=O)C1=C(N)[N](CC2=CC(=C(C(=C2)Cl)C(=O)C3=CC=C(Cl)C=C3)Cl)N=N1.OC(=O)C4=CC(=O)NC(=O)N4",{"v":2.65,"d":"2.650"},7,4,6]
["S3494","Vicriviroc maleate","f4","L3800-45","in 10mM DMSO","N/A","N/A","Phase II","CCR,HIV Protease","GPCR & G Protein","Vicriviroc maleate(SCH-417690 maleate,SCH-D maleate) is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5, with a Ki of 2.5 nM, and also inhibits HIV-1 in PBMC cells.",{"v":649.7,"d":"649.70"},"599179-03-0",{"v":100,"d":"100.00"},153.92,{"v":50,"d":"50.00"},76.96,"http://www.selleckchem.com/products/vicriviroc-maleate.html","C32H42F3N5O6","Maleate","SCH-417690 maleate, SCH-D maleate","COCC(N1CCN(CC1C)C2(C)CCN(CC2)C(=O)C3=C(C)N=CN=C3C)C4=CC=C(C=C4)C(F)(F)F.OC(=O)\\C=C/C(O)=O",-2.926,6,0,9]
["S5218","Iodixanol","a5","L3800-45","in 10mM DMSO","FDA,CFDA,PMDA,NDC,DMF","USP43-NF38,EP10.6","Marketed","Others","Others","Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography.",1550.18,"92339-11-2",{"v":100,"d":"100.00"},64.51,"<1","N/A","http://www.selleckchem.com/products/iodixanol.html","C35H44I6N6O15","Free base","N/A","CC(=O)N(CC(O)CN(C(C)=O)C1=C(I)C(=C(I)C(=C1I)C(=O)NCC(O)CO)C(=O)NCC(O)CO)C2=C(I)C(=C(I)C(=C2I)C(=O)NCC(O)CO)C(=O)NCC(O)CO",-2.279,6,13,22]
["S6672","PF-05175157","e5","L3800-45","in 10mM DMSO","N/A","N/A","Phase II","Acetyl-CoA carboxylase","Metabolism","PF-05175157 is a broad-spectrum effective ACC inhibitor with IC50 of 27.0 nM, 33.0 nM, 23.5 nM and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively.",405.49,"1301214-47-0",{"v":30,"d":"30.00"},73.98,"<1","N/A","http://www.selleckchem.com/products/pf-05175157.html","C23H27N5O2","Free base","N/A","CC(C)[N]1N=CC2=C1C(=O)CC3(CCN(CC3)C(=O)C4=CC=C5N=C(C)[NH]C5=C4)C2",2.674,4,1,2]
["S6839","MRX-2843","a6","L3800-45","in 10mM DMSO","N/A","N/A","Phase 2","FLT3,Mertk","Protein Tyrosine Kinase","MRX-2843 (UNC2371) is an orally active dual inhibitor of tyrosine kinases MERTK and FLT3 with IC50 of 1.3 nM and 0.64 nM, respectively.",488.67,"1429882-07-4",{"v":98,"d":"98.00"},200.54,"<1","N/A","http://www.selleckchem.com/products/mrx-2843.html","C29H40N6O","Free base","UNC2371","CN1CCN(CC1)CC2=CC=C(C=C2)C3=C[N](C4CCC(O)CC4)C5=NC(=NC=C35)NCCC6CC6",4.459,2,2,8]
["S6984","Dianhydrogalactitol (VAL-083)","d6","L3800-45","in 10mM DMSO","CFDA","ChP39160","Marketed","DNA alkylator","DNA Damage/DNA Repair","Dianhydrogalactitol (VAL-083, Dianhydrodulcitol, Dulcitol Diepoxide) is a bi-functional alkylating agent that readily crosses the blood-brain barrier and creates N7 methylation on DNA. Dianhydrogalactitol shows antitumor activity.",146.14,"23261-20-3",{"v":29,"d":"29.00"},198.44,{"v":29,"d":"29.00"},198.44,"http://www.selleckchem.com/products/dianhydrogalactitol-val-083.html","C6H10O4","Free base","Dianhydrodulcitol, Dulcitol Diepoxide","OC(C(O)C1CO1)C2CO2",-1.408,2,2,3]
["S7554","Ravoxertinib (GDC-0994)","g6","L3800-45","in 10mM DMSO","N/A","N/A","Phase 1","ERK","MAPK","Ravoxertinib (GDC-0994) is a potent, orally available  and highly selective ERK1/2 inhibitor with IC50 of 1.1 nM and 0.3 nM, respectively. Phase 1.",439.85,"1453848-26-4",{"v":87,"d":"87.00"},197.79,"<1","N/A","http://www.selleckchem.com/products/gdc-0994.html","C21H18ClFN6O2","Free base","N/A","C[N]1N=CC=C1NC2=NC=CC(=N2)C3=CC(=O)N(C=C3)C(CO)C4=CC(=C(Cl)C=C4)F",2.798,4,2,6]
["S7739","Telacebec (Q203)","h6","L3800-45","in 10mM DMSO","N/A","N/A","Phase II","Bacterial","Microbiology","Telacebec (Q203, IAP6) is a novel antituberculosis drug that targets Mycobacterium tuberculosis cellular energy production through inhibition of the mycobacterial cytochrome bc1 complex. Telacebec (Q203, IAP6) is active against Mycobacterium tuberculosis H37Rv with MIC50 of 2.7 nM in culture broth medium.",557.01,"1334719-95-7",{"v":20,"d":"20.00"},35.91,"<1","N/A","http://www.selleckchem.com/products/telacebec-q203.html","C29H28ClF3N4O2","Free base","IAP6","CCC1=C([N]2C=C(Cl)C=CC2=N1)C(=O)NCC3=CC=C(C=C3)N4CCC(CC4)C5=CC=C(OC(F)(F)F)C=C5",7.887,3,1,8]
["S7930","Ixabepilone (BMS-247550)","c7","L3800-45","in 10mM DMSO","FDA,DMF","USPNF 2022 Issue 1","Marketed","Microtubule Associated","Cytoskeletal Signaling","Ixabepilone (Azaepothilone B, BMS-247550, Ixempra, Aza-epothilone B) is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis.",{"v":506.7,"d":"506.70"},"219989-84-1",{"v":100,"d":"100.00"},197.36,"<1","N/A","http://www.selleckchem.com/products/ixabepilone-bms-247550.html","C27H42N2O5S","Free base","Azaepothilone B, BMS-247550, Ixempra, Aza-epothilone B","CC1CCCC2(C)OC2CC(NC(=O)CC(O)C(C)(C)C(=O)C(C)C1O)C(/C)=C/C3=CSC(=N3)C",3.132,4,3,2]
["S8524","Edicotinib(JNJ-40346527)","g7","L3800-45","in 10mM DMSO","N/A","N/A","Phase II","CSF-1R","Protein Tyrosine Kinase","Edicotinib (JNJ-40346527) is a potent, selective, brain penetrant and orally active colony-stimulating factor-1 receptor (CSF-1R) inhibitor with an IC50 of 3.2 nM.",{"v":461.6,"d":"461.60"},"1142363-52-7",{"v":92,"d":"92.00"},199.31,"<1","N/A","http://www.selleckchem.com/products/edicotinib.html","C27H35N5O2","Free base","N/A","CC1(C)CCC(=CC1)C2=NC(=CC=C2NC(=O)C3=NC=C([NH]3)C#N)C4CC(C)(C)OC(C)(C)C4",{"v":4.56,"d":"4.560"},4,2,4]
["S8600","Elenbecestat","b8","L3800-45","in 10mM DMSO","N/A","N/A","Phase III","BACE","Neuronal Signaling","Elenbecestat (E2609) is a novel BACE1 inhibitor, demonstrating prolonged reductions in plasma beta-amyloid levels after single dosing.",437.44,"1388651-30-6",{"v":87,"d":"87.00"},198.88,"<1","N/A","http://www.selleckchem.com/products/elenbecestat.html","C19H18F3N5O2S","Free base","E2609","CC1OCC2(N=C(N)SCC12)C3=C(F)C=CC(=C3)NC(=O)C4=CN=C(C=N4)C(F)F",2.037,5,2,4]
["S8716","Pralsetinib (BLU-667)","e8","L3800-45","in 10mM DMSO","FDA,EMA,CFDA,NDC","N/A","Marketed","c-RET","Apoptosis","Pralsetinib (BLU-667, CS 3009, Gavreto) is a highly potent and selective RET (c-RET) inhibitor with an IC50 of 0.4 nM for WT RET. It also demonstrates potent activity (IC50 0.4 nmol/L) against common oncogenic RET alterations, including RET (M918T).",{"v":533.6,"d":"533.60"},"2097132-94-8",{"v":100,"d":"100.00"},187.41,"<1","N/A","http://www.selleckchem.com/products/blu-667.html","C27H32FN9O2","Free base","CS 3009, Gavreto","COC1(CCC(CC1)C2=NC(=CC(=N2)NC3=N[NH]C(=C3)C)C)C(=O)NC(C)C4=CN=C(C=C4)[N]5C=C(F)C=N5",3.716,7,3,8]
["S8829","Subasumstat (TAK-981)","a9","L3800-45","in 10mM DMSO","N/A","N/A","Phase 2","SUMO","Ubiquitin","Subasumstat (TAK-981) is a novel, selective inhibitor of the SUMOylation enzymatic cascade with potential immune-activating and antineoplastic activities.",{"v":578.1,"d":"578.10"},"1858276-04-6",{"v":100,"d":"100.00"},172.98,"<1","N/A","http://www.selleckchem.com/products/tak-981.html","C25H28ClN5O5S2","Free base","N/A","CC1=C(C=C(S1)C(=O)C2=C(NC3CC(O)C(CO[S](N)(=O)=O)C3)N=CN=C2)C4NCCC5=C4C=C(Cl)C=C5",2.094,4,4,8]
["S8851","Elexacaftor (VX-445)","d9","L3800-45","in 10mM DMSO","FDA,EMA,NDC","N/A","Marketed","CFTR","Transmembrane Transporters","Elexacaftor (VX-445) is a next-generation cystic fibrosis transmembrane conductance regulator (CFTR) corrector.This is a compound which is not chiral purity.",597.65,"2216712-66-0",{"v":100,"d":"100.00"},167.32,"<1","N/A","http://www.selleckchem.com/products/elexacaftor.html","C26H34F3N7O4S","Free base","N/A","CC1CN(C2=C(C=CC(=N2)[N]3C=CC(=N3)OCC(C)(C)C(F)(F)F)C(=O)N[S](=O)(=O)C4=C[N](C)N=C4C)C(C)(C)C1",5.245,7,1,9]
["S8884","Adagrasib (MRTX849)","g9","L3800-45","in 10mM DMSO","N/A","N/A","Phase III","Ras","Cell Cycle","Adagrasib (MRTX849) is a potent, selective, and covalent KRASG12C inhibitor that exhibits favorable drug-like properties, selectively modifies mutant cysteine 12 in GDP-bound KRASG12C and inhibits KRAS-dependent signaling.",604.12,"2326521-71-3",{"v":100,"d":"100.00"},165.53,"<1","N/A","http://www.selleckchem.com/products/mrtx849.html","C32H35ClFN7O2","Free base","N/A","CN1CCCC1COC2=NC3=C(CCN(C3)C4=CC=CC5=C4C(=CC=C5)Cl)C(=N2)N6CCN(C(CC#N)C6)C(=O)C(F)=C",5.325,4,0,7]
["S8890","MK-8719","h9","L3800-45","in 10mM DMSO","N/A","N/A","Phase 1","OGA","Autophagy","MK-8719 is a selective and potent small molecule inhibitor of the O-GlcNAcase (OGA) enzyme with ki of 7.9nM for hOGA.",268.28,"1382799-40-7",{"v":54,"d":"54.00"},201.28,{"v":54,"d":"54.00"},201.28,"http://www.selleckchem.com/products/mk-8719.html","C9H14F2N2O3S","Free base","N/A","CCNC1=NC2C(O)C(O)C(OC2S1)C(F)F",0.439,2,3,3]
["S8939","Mizagliflozin (KWA 0711)","c10","L3800-45","in 10mM DMSO","N/A","N/A","Phase II","SGLT","GPCR & G Protein","Mizagliflozin (KWA 0711) is a novel, potent, selective sodium glucose co-transporter 1 (SGLT1) inhibitor with Ki of 27 nM for human SGLT1. The selectivity ratio (Ki value for human SGLT2/Ki value for human SGLT1) of mizagliflozin is 303. Mizagliflozin shows the potential use for the amelioration of chronic constipation.",564.67,"666843-10-3",{"v":100,"d":"100.00"},177.09,{"v":100,"d":"100.00"},177.09,"http://www.selleckchem.com/products/mizagliflozin.html","C28H44N4O8","Free base","N/A","CC(C)C1=C(CC2=C(C)C=C(OCCCNCC(C)(C)C(N)=O)C=C2)C(=N[NH]1)OC3OC(CO)C(O)C(O)C3O",2.007,5,7,14]
["S8966","T-5224","g10","L3800-45","in 10mM DMSO","N/A","N/A","Phase II","Interleukins,MMP","Proteases","T-5224 is a selective inhibitor of transcription factor c-Fos/activator protein (AP)-1 with anti-inflammatory effects. T-5224 specifically inhibits the DNA binding activity of c-Fos/c-Jun and the IL-1β-induced up-regulation of Mmp-3, Mmp-13 and Adamts-5 transcription.",517.53,"530141-72-1",{"v":100,"d":"100.00"},193.23,"<1","N/A","http://www.selleckchem.com/products/t-5224.html","C29H27NO8","Free base","N/A","OC(=O)CCC1=CC(=CC=C1OCC2=CC3=C(C=C2)C(=NO3)O)C(=O)C4=CC=C(OC5CCCC5)C=C4O",6.016,6,2,10]
["S8999","Exatecan Mesylate","b11","L3800-45","in 10mM DMSO","DMF","N/A","Phase III","Topoisomerase","DNA Damage/DNA Repair","Exatecan Mesylate (DX-8951f) is a water-soluble and non-pro-drug analog of camptothecin and shows significant topoisomerase I inhibition with IC50 of 0.975 μg/ml.",531.55,"169869-90-3",{"v":12.5,"d":"12.50"},23.52,{"v":12.5,"d":"12.50"},23.52,"http://www.selleckchem.com/products/exatecan-mesylate.html","C24H22FN3O4.CH4O3S","Mesylate","DX-8951 Mesylate","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C5C(N)CCC6=C5C(=CC(=C6C)F)N=C34)C2=O.C[S](O)(=O)=O",1.689,4,1,1]
["S9608","Etrumadenant (AB928)","e11","L3800-45","in 10mM DMSO","N/A","N/A","Phase II","Adenosine Receptor","GPCR & G Protein","Etrumadenant (AB928, A2aR/A2bR antagonist-1) is a novel dual A2aR/A2bR antagonist with Kd of 1.4 nM and 2 nM for A2aR and A2bR, respectively.",426.47,"2239273-34-6",{"v":85,"d":"85.00"},199.31,"<1","N/A","http://www.selleckchem.com/products/ab928.html","C23H22N8O","Free base","A2aR/A2bR antagonist-1","CC1=C(C=CC=C1C#N)C2=CC(=NC(=N2)N)C3=C[N](CC4=CC=CC(=N4)C(C)(C)O)N=N3",{"v":3.75,"d":"3.750"},5,1,5]
["S9702","Finerenone","a2","L3800-46","in 10mM DMSO","FDA,EMA,PMDA,NDC","N/A","Marketed","Mineralocorticoid Receptor","Endocrinology & Hormones","Finerenone (FIN, BAY 94-8862) is a highly selective and orally available nonsteroidal antagonist of mineralocorticoid receptor (MR) with IC50 of 18 nM. Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.",378.42,"1050477-31-0",{"v":76,"d":"76.00"},200.84,"<1","N/A","http://www.selleckchem.com/products/finerenone.html","C21H22N4O3","Free base","FIN, BAY 94-8862","CCOC1=NC=C(C)C2=C1C(C3=CC=C(C=C3OC)C#N)C(=C(C)N2)C(N)=O",2.613,4,2,5]
["S9858","Lufotrelvir (PF-07304814)","d2","L3800-46","in 10mM DMSO","N/A","N/A","Phase 3","COVID-19","Microbiology","PF-07304814 is a phosphate prodrug of PF-00835231 that binds and inhibits SARS-CoV-2 3CLpro activity with a Ki of 174 nM.",552.51,"2468015-78-1",{"v":100,"d":"100.00"},180.99,{"v":50,"d":"50.00"},{"v":90.5,"d":"90.50"},"http://www.selleckchem.com/products/lufotrelvir-pf-07304814.html","C24H33N4O9P","Free base","N/A","COC1=CC=CC2=C1C=C([NH]2)C(=O)NC(CC(C)C)C(=O)NC(CC3CCNC3=O)C(=O)CO[P](O)(O)=O",1.036,6,4,13]
["S9866","Nirmatrelvir (PF-07321332)","e2","L3800-46","in 10mM DMSO","CFDA,NDC","N/A","Marketed","COVID-19,SARS-CoV","Microbiology","Nirmatrelvir (PF-07321332) is an reversible covalent inhibitor of SARS-CoV-2 main protease (Mpro, also referred to as 3CL protease) with an ki of 3.11 nM. PF-07321332 binds directly to the catalytic cysteine (Cys145) residue of the enzyme.",499.53,"2628280-40-8",{"v":100,"d":"100.00"},200.19,{"v":2,"d":"2.00"},{"v":4,"d":"4.00"},"http://www.selleckchem.com/products/pf-07321332.html","C23H32F3N5O4","Free base","N/A","CC(C)(C)C(NC(=O)C(F)(F)F)C(=O)N1CC2C(C1C(=O)NC(CC3CCNC3=O)C#N)C2(C)C",0.799,4,3,8]
["S9901","KB-0742 Dihydrochloride","g2","L3800-46","in 10mM DMSO","N/A","N/A","Phase 2","CDK","Cell Cycle","KB-0742 Dihydrochloride is a potent, selective, and orally bioavailable small molecule inhibitor of the transcription elongation cofactor CDK9 with IC50 of 6 nM for CDK9/cyclin T1 inhibition at 10 μM ATP.",360.33,"2416874-75-2",{"v":72,"d":"72.00"},199.82,{"v":72,"d":"72.00"},199.82,"http://www.selleckchem.com/products/kb-0742-dihydrochloride.html","C16H25N5.2ClH","Dihydrochloride","N/A","Cl.Cl.CCC(CC)C1=NC2=CC=N[N]2C(=C1)NC3CCC(N)C3",3.291,2,2,5]
["S9975","ASN007","b3","L3800-46","in 10mM DMSO","N/A","N/A","Phase 1","ERK","MAPK","ASN007(ERAS 007, ERK-IN-3) is a potent and orally active inhibitor of ERK. ERK-IN-3 inhibits ERK1/2 with 2 nM IC50 values. ERK-IN-3 can be used for the research of cancers driven by RAS mutations.",473.93,"2055597-12-9",{"v":95,"d":"95.00"},200.45,"<1","N/A","https://www.selleckchem.com/products/asn007.html","C22H25ClFN7O2","Free base","ERAS 007,ERK-IN-3","CC1=CN=C(NC2CCOCC2)N=C1[N]3C=NC(=C3)C(=O)NC(CN)C4=CC(=CC(=C4)F)Cl",2.206,5,3,7]
["E0114","Dilmapimod (SB-681323)","f3","L3800-46","in 10mM DMSO","N/A","N/A","Phase II","p38 MAPK","MAPK","Dilmapimod (SB-681323,GW 681323) is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease.",456.42,"444606-18-2",{"v":91,"d":"91.00"},199.38,"<1","N/A","http://www.selleckchem.com/products/dilmapimod-sb-681323.html","C23H19F3N4O3","Free base","GW 681323","CC1=CC(=CC=C1C2=C3C=CC(=O)N(C3=NC(=N2)NC(CO)CO)C4=C(F)C=CC=C4F)F",4.124,3,3,6]
["E0164","Antazoline Phosphate","a4","L3800-46","in 10mM DMSO","FDA,CFDA","USPNF 2022 Issue 1,EP10.8","Marketed","Histamine Receptor","Neuronal Signaling","Antazoline Phosphate is the phosphate salt of antazoline. Antazoline is a first-generation antihistaminic agent and acts as a histamine H1 receptor antagonist.",363.35,"154-68-7",{"v":18,"d":"18.00"},49.54,{"v":73,"d":"73.00"},200.91,"http://www.selleckchem.com/products/antazoline-phosphate.html","C17H19N3.H3O4P","Phosphate","N/A","O[P](O)(O)=O.C1CN=C(CN(CC2=CC=CC=C2)C3=CC=CC=C3)N1",2.246,1,1,5]
["E0616","Chiauranib","d4","L3800-46","in 10mM DMSO","N/A","N/A","Phase III","Aurora Kinase,c-Kit,CSF-1R,PDGFR,VEGFR","Protein Tyrosine Kinase","Chiauranib (CS2164) selectively inhibits multiple kinase targets aurora B kinase (AURKB), colony-stimulating factor 1 receptor (CSF1R), and vascular endothelial growth factor receptor (VEGFR)/platelet-derived growth factor receptor (PDGFR)/c-Kit , thereby inhibiting the rapid proliferation of tumor cells, enhancing the antitumor immunity, and inhibiting tumor angiogenesis, to achieve the anti-tumor efficacy.",{"v":435.5,"d":"435.50"},"1256349-48-0",{"v":87,"d":"87.00"},199.77,"<1","N/A","http://www.selleckchem.com/products/chiauranib.html","C27H21N3O3","Free base","CS2164","COC1=CC2=C(C=C1)C(=CC=N2)OC3=CC4=C(C=C3)C(=CC=C4)C(=O)NC5=C(N)C=CC=C5",4.506,4,2,5]
["E1013","Bemnifosbuvir Hemisulfate (AT-527)","h4","L3800-46","in 10mM DMSO","N/A","N/A","Phase III","SARS-CoV","Microbiology","Bemnifosbuvir Hemisulfate (AT-527, RG-6422, RO 7496998) is a hemi-sulfate salt of AT-511. AT-511 is a potent inhibitor of SARS-CoV-2 with an EC90 of 0.47 μM.",630.55,"2241337-84-6",{"v":100,"d":"100.00"},147.14,{"v":100,"d":"100.00"},147.14,"http://www.selleckchem.com/products/bemnifosbuvir-hemisulfate-at-527.html","C24H33FN7O7P.1/2H2O4S","Hemisulfate","RG-6422, RO 7496998","CNC1=C2N=C[N](C3OC(CO[P](=O)(NC(C)C(=O)OC(C)C)OC4=CC=CC=C4)C(O)C3(C)F)C2=NC(=N1)N.O[S](O)(=O)=O",1.948,8,4,12]
["E1111","VV116","c5","L3800-46","in 10mM DMSO","N/A","N/A","Phase III","COVID-19,DNA/RNA Synthesis,SARS-CoV","Microbiology","VV116, a promising orally administered anti-SARS-CoV-2 nucleoside drug candidate, exerts functions by targeting the viral RNA-dependent RNA polymerase through its nucleoside triphosphate form with an IC50 of 0.67±0.24 μM.",502.54,"2647442-33-7(free base)",{"v":100,"d":"100.00"},198.99,"<1","N/A","http://www.selleckchem.com/products/vv116.html","C24H30DN5O7","Free base","JT001","CC(C)C(=O)OCC1OC(C#N)(C(OC(=O)C(C)C)C1OC(=O)C(C)C)C2=CC(=C3[N]2N=CN=C3N)[2H]",3.095,9,1,11]
["E1131","Ensitrelvir fumarate","d5","L3800-46","in 10mM DMSO","N/A","N/A","Phase III","COVID-19,SARS-CoV","Microbiology","S-217622 (Ensitrelvir fumarate) is the first orally active non-covalent, non-peptidic, SARS-CoV-2 3CL protease inhibitor with IC50 of 13 nM.",647.95,"2757470-18-9",{"v":50,"d":"50.00"},77.17,"<1","N/A","http://www.selleckchem.com/products/s-217622.html","C22H17ClF3N9O2.C4H4O4","fumarate","S-217622 fumarate","C[N]1C=NC(=N1)CN2C(=O)NC(=NC3=CC4=C[N](C)N=C4C=C3Cl)N(CC5=C(F)C=C(F)C(=C5)F)C2=O.OC(=O)\\C=C\\C(O)=O",5.384,8,1,7]
["E1184","CFT7455","g5","L3800-46","in 10mM DMSO","N/A","N/A","Phase 2","Others","Others","CFT7455 is an orally active zinc finger transcription factors (IKZF1) (Ikaros) and IKZF3 (Aiolos) degrader. It binds with high affinity to the cereblon E3 ligase (Kd of 0.9 nM). It is used in the treatment of multiple myeloma & non-Hodgkin’s lymphoma.",469.53,"2504235-67-8",{"v":94,"d":"94.00"},{"v":200.2,"d":"200.20"},"<1","N/A","https://www.selleckchem.com/products/cft7455.html","C28H27N3O4","Free base","N/A","O=C1CCC(N2C(=O)C3=C4C2=CC=C(CC5=CC=C(CN6CCOCC6)C=C5)C4=CC=C3)C(=O)N1",2.869,4,1,5]
["E1208","NPX800","b6","L3800-46","in 10mM DMSO","N/A","N/A","Phase 1","HSP (HSP90)","Metabolism","NPX800 is a potent heat shock factor 1 (HSF1) inhibitor, which has the potential for cancer research.",569.63,"1693734-80-3",{"v":100,"d":"100.00"},175.55,"<1","N/A","http://www.selleckchem.com/products/npx800.html","C32H32FN5O4","Free base","N/A","CCN1CCN(CC1)CC2=NC3=C(C=C2)C=C(C=C3)C(=O)NC4=CC(=CC=C4F)NC(=O)C5=CC=C6OCCOC6=C5",4.171,5,2,7]
["E2399","Falnidamol","f6","L3800-46","in 10mM DMSO","N/A","N/A","Phase 1","EGFR,p38 MAPK","Protein Tyrosine Kinase","Falnidamol (BIBX1382) is a selective inhibitor of epidermal growth factor receptor (EGFR), exerting anti-cancer role in human head and neck squamous cell carcinomas both in vitro and in vivo through suppressing mitogen-activated protein kinases (MAPKs) signaling.",387.84,"196612-93-8",{"v":20,"d":"20.00"},51.57,"<1","N/A","http://www.selleckchem.com/products/falnidamol.html","C18H19ClFN7","Free base","BIBX1382","CN1CCC(CC1)NC2=NC=C3N=CN=C(NC4=CC=C(F)C(=C4)Cl)C3=N2",3.437,4,2,4]
["E2629","Vimseltinib","a7","L3800-46","in 10mM DMSO","N/A","N/A","Phase III","c-Kit,CSF-1R","Protein Tyrosine Kinase","Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor extracted from patent WO2014145025A2, Compound Example 10, has IC50s of <0.01 μM and 0.1-1 μM, respectively.",431.49,"1628606-05-2",{"v":86,"d":"86.00"},199.31,"<1","N/A","http://www.selleckchem.com/products/vimseltinib.html","C23H25N7O2","Free base","DCC-3014","CC(C)NC1=NC=C(C(=O)N1C)C2=CC=C(OC3=CC=NC(=C3)C4=C[N](C)N=C4)C(=N2)C",2.226,6,1,6]
["E2665","Tafenoquine","d7","L3800-46","in 10mM DMSO","FDA,DMF","N/A","Marketed","Anti-infection","Others","Tafenoquine (WR 238605) is an 8-aminoquinoline, used as an anti-malarial prophylactic agent.",463.49,"106635-80-7",{"v":93,"d":"93.00"},200.65,"<1","N/A","http://www.selleckchem.com/products/tafenoquine.html","C24H28F3N3O3","Free base","WR 238605","COC1=NC2=C(C(=C1)C)C(=C(OC)C=C2NC(C)CCCN)OC3=CC(=CC=C3)C(F)(F)F",{"v":5.51,"d":"5.510"},4,2,10]
["E2843","Poseltinib","h7","L3800-46","in 10mM DMSO","N/A","N/A","Phase II","BTK","Angiogenesis","Poseltinib (HM71224, LY3337641) shows a highly selective inhibition for Bruton’s tyrosine kinase (BTK) with IC50 of 1.95 nM, in which the selectivity toward other BMX, TEC and TXK are 0.3, 2.3 and 2.4 fold, respectively.",470.52,"1353552-97-2",{"v":94,"d":"94.00"},199.78,"<1","N/A","http://www.selleckchem.com/products/poseltinib.html","C26H26N6O3","Free base","HM71224, LY3337641","CN1CCN(CC1)C2=CC=C(NC3=NC(=C4OC=CC4=N3)OC5=CC(=CC=C5)NC(=O)C=C)C=C2",4.891,5,2,7]
["P1032","CCK Octapeptide (Sincalide)","c8","L3800-46","in 10mM DMSO","FDA","N/A","Marketed","Others","Others","CCK Octapeptide (Sincalide, Cholecystokinin Octapeptide, CCK-OP, CCK-8, SQ 19,844) is a endogenous peptide hormone found in the intestine and brain that stimulates digestion.",1143.27,"25126-32-3",{"v":100,"d":"100.00"},87.47,"<1","N/A","http://www.selleckchem.com/products/Sincalide(Kinevac).html","C49H62N10O16S3","Free base","Cholecystokinin Octapeptide, CCK-OP, CCK-8, SQ 19,844","CSCCC(NC(=O)C(CC1=CC=C(O[S](O)(=O)=O)C=C1)NC(=O)C(N)CC(O)=O)C(=O)NCC(=O)NC(CC2=C[NH]C3=CC=CC=C23)C(=O)NC(CCSC)C(=O)NC(CC(O)=O)C(=O)NC(CC4=CC=CC=C4)C(N)=O",-3.722,11,10,33]
["P1069","Ganirelix acetate (Antagon)","d8","L3800-46","in 10mM DMSO","FDA,EMA,CFDA,PMDA,NDC,DMF","N/A","Marketed","Others","Endocrinology & Hormones","Ganirelix acetate (Antagon,Orgalutran) is a synthetic decapeptide with high antagonistic activity against naturally occurring gonadotropin-releasing hormone (GnRH).",1690.43,"123246-29-7",{"v":100,"d":"100.00"},59.16,{"v":100,"d":"100.00"},59.16,"http://www.selleckchem.com/peptide/ganirelix-acetate-antagon.html","C80H113ClN18O13.2C2H4O2","Diacetate","Orgalutran","CCNC(NCC)=NCCCCC(NC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C(CO)NC(=O)C(CC2=CN=CC=C2)NC(=O)C(CC3=CC=C(Cl)C=C3)NC(=O)C(CC4=CC5=C(C=CC=C5)C=C4)NC(C)=O)C(=O)NC(CC(C)C)C(=O)NC(CCCCN=C(NCC)NCC)C(=O)N6CCCC6C(=O)NC(C)C(N)=O.CC(O)=O.CC(O)=O",3.056,16,16,48]
["P1144","Antide","g8","L3800-46","in 10mM DMSO","N/A","N/A","Phase II","Apoptosis related,GNRH Receptor","Endocrinology & Hormones","Antide(Iturelix), a gonadotropin-releasing hormone (GNRH) antagonist, inhibits apoptosis of preovulatory follicle cells in the rat ovary.",{"v":1591.3,"d":"1591.30"},"112568-12-4",{"v":100,"d":"100.00"},62.84,{"v":50,"d":"50.00"},31.42,"http://www.selleckchem.com/products/antide.html","C82H108ClN17O14","Free base","Iturelix","CC(C)CC(NC(=O)C(CCCCNC(=O)C1=CN=CC=C1)NC(=O)C(CCCCNC(=O)C2=CN=CC=C2)NC(=O)C(CO)NC(=O)C(CC3=CN=CC=C3)NC(=O)C(CC4=CC=C(Cl)C=C4)NC(=O)C(CC5=CC6=CC=CC=C6C=C5)NC(C)=O)C(=O)NC(CCCCNC(C)C)C(=O)N7CCCC7C(=O)NC(C)C(N)=O",{"v":2.35,"d":"2.350"},16,14,46]
["E4074","p-Toluic acid","b9","L3800-46","in 10mM DMSO","N/A","USP42-NF37","N/A","Endogenous Metabolite","Metabolism","p-Toluic Acid belongs to the class of organic compounds known as benzoic acids. 4-Methylbenzoic acid has been primarily detected in saliva. Within the cell, 4-methylbenzoic acid is primarily located in the cytoplasm.",136.15,"99-94-5","N/A",">10","N/A","N/A","https://www.selleckchem.com/products/p-toluic-acid.html","C8H8O2","free base","p-Toluic Acid","CC1=CC=C(C=C1)C(O)=O",1.946,1,0,1]
["E4234","1-Octanol","g9","L3800-46","in 10mM DMSO","N/A","N/A","Phase 2","calcium channel; Endogenous Metabolite","Membrane transporter/Ion channel; Metabolism","1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents[1]. 1-Octanol is a highly attractive biofuel with diesel-like properties[2].",130.23,"111-87-5","N/A",">10","N/A","N/A","https://www.selleckchem.com/products/1-octanol.html","C8H18O","free base","1-Octanol","CCCCCCCCO",2.795,0,1,6]
["E4324","1,3-BUTANEDIOL","a10","L3800-46","in 10mM DMSO","N/A","N/A","Phase 2","Endogenous Metabolite","Metabolism","1,3-Butanediol (BD) is a ketogenic substance. Ketone bodies are essential energy substrates in the absence of exogenous nutrients, and more recently, they have been suggested to prevent disease and improve longevity.",90.12,"107-88-0","N/A",">10","N/A","N/A","https://www.selleckchem.com/products/1-3-butanediol.html","C4H10O2","free base","1,3-BUTANEDIOL","CC(O)CCO",-0.458,0,2,2]
["E4434","Phenylephrine","e10","L3800-46","in 10mM DMSO","FDA,EMA,HMA,NDC,DMF,PMDA","JP18;BP2024;USP-NF2024;EP11.0;IP2010","Marketed","Adrenergic Receptor","GPCR/G Protein;Neuroscience","Phenylephrine is a selective α1-adrenoceptor agonist ( pKi: 5.86, 4.87 and 4.70 for α1D, α1B, and α1A receptors respectively).",167.21,"59-42-7","N/A",">10","N/A","N/A","https://www.selleckchem.com/products/phenylephrine.html","C9H13NO2","free base","Phenylephrine","CNCC(O)C1=CC(=CC=C1)O",0.615,0,3,3]
["E4494","Se-Methylselenocysteine","h10","L3800-46","in 10mM DMSO","N/A","N/A","Phase 1","Caspase;BCL;IAP","Apoptosis;Proteases/Proteasome","Se-Methylselenocysteine is a potent chemopreventive agent in many test systems and has been shown to inhibit tumor promotion and induce apoptosis.",182.08,"26046-90-2","N/A",">10","N/A","N/A","https://www.selleckchem.com/products/se-methylselenocysteine.html","C4H9NO2Se","free base","Se-Methylselenocysteine","C[Se]CC(N)C(O)=O",-2.442,1,1,3]
["E4499","Levomenol","c11","L3800-46","in 10mM DMSO","N/A","BP2017, BP2013, BP2010","Phase 1","Others","Others","Levomenol is a sesquiterpene alcohol that has been found in the essential oils of several aromatic plants, with exerts antioxidant, anti-inflammatory, and anti-apoptotic activities.",222.37,"23089-26-1","N/A",">10","N/A","N/A","https://www.selleckchem.com/products/levomenol.html","C15H26O","Free base","Levomenol","CC(C)=CCCC(C)(O)C1CCC(=CC1)C",4.309,0,0,4]
["S7830","Coenzyme A","d11","L3800-46","in 10mM DMSO","N/A","N/A","Phase 3","Endogenous Metabolite","Metabolism","Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.",767.53,"85-61-0","N/A",">10","N/A","N/A","https://www.selleckchem.com/products/coenzyme-a.html","C21H36N7O16P3S","Free base","Coenzyme A","CC(C)(CO[P](O)(=O)O[P](O)(=O)OCC1OC(C(O)C1O[P](O)(O)=O)[N]2C=NC3=C(N)N=CN=C23)C(O)C(=O)NCCC(=O)NCCS",-2.962,10,5,18]
["E4271","1-Naphthol","g11","L3800-46","in 10mM DMSO","N/A","USP42-NF37","Phase 1","Others","Others","1-Naphthol is an organic compound obtained from the aromatic hydrocarbon naphthalene. It acts as a catalyst in the polymerization process of vinyl monomers and plays a vital role in the synthesis of 1-naphthylacetic acid and its derivatives as a reactant.",144.17,"90-15-3","N/A",">10","N/A","N/A","https://www.selleckchem.com/products/1-naphthol.html","C10H8O","Free base","Furro ER, NSC 9586, Nako TRB, 1-hydroxy-naphthalene","OC1=CC=CC2=C1C=CC=C2",2.496,0,1,0]
["E0359","Evocalcet","b2","L3800-47","in 10mM DMSO","PMDA","N/A","marketed","CaSR","GPCR & G Protein","Evocalcet (KHK7580) is an novel oral calcimimetic agent which acts via allosteric activation of the calcium sensing receptor (CaSR). Evocalcet (0, 20 and 60 nM) dose-dependently increases cytoplasmic  [Ca2+] concentrations  with an EC50 value of 92.7 nM in hCaR-HEK293 cells.",374.48,"870964-67-3",{"v":75,"d":"75.00"},200.28,"<1","N/A","https://www.selleckchem.com/products/evocalcet.html","C24H26N2O2","free base","KHK7580","CC(NC1CCN(C1)C2=CC=C(CC(O)=O)C=C2)C3=CC=CC4=C3C=CC=C4",1.334,1,1,6]
["E1321","Digitonin","f2","L3800-47","in 10mM DMSO","N/A","N/A","marketed","Others","Others","Digitonin, a steroidal saponin and glycoside obtained from <i>Digitalis purpurea</i>, has strong lytic activity on various cell membranes with an IC50 of 15.1 µM on sheep RBC membranes.",1229.31,"11024-24-1",{"v":100,"d":"100.00"},81.35,"<1","N/A","https://www.selleckchem.com/products/digitonin.html","C56H92O29","free base","N/A","CC1CCC2(OC1)OC3C(O)C4C5CCC6CC(OC7OC(CO)C(OC8OC(CO)C(O)C(OC9OCC(O)C(O)C9O)C8OC%10OC(CO)C(O)C(OC%11OC(CO)C(O)C(O)C%11O)C%10O)C(O)C7O)C(O)CC6(C)C5CCC4(C)C3C2C",-5.207,12,17,14]
["E1342","Sebetralstat","a3","L3800-47","in 10mM DMSO","N/A","N/A","Phase 3","Serine protease","Protease","Sebetralstat(KVD900) is a plasma kallikrien inhibitor.",491.52,"1933514-13-6",{"v":98,"d":"98.00"},199.38,"<1","N/A","https://www.selleckchem.com/products/sebetralstat-kvd900.html","C26H26FN5O4","free base","KVD900","COCC1=N[N](CC2=CC=C(CN3C=CC=CC3=O)C=C2)C=C1C(=O)NCC4=NC=CC(=C4F)OC",1.763,6,1,10]
["E1382","BI 1015550","e3","L3800-47","in 10mM DMSO","N/A","N/A","Phase 3","PDE","Metabolism","BI 1015550 is an orally active inhibitor of PDE4B with IC50 of 7.2 nM. It has good safety and potential applications in inflammation, allergic diseases, pulmonary fibrosis, and chronic obstructive pulmonary disease (COPD).",448.97,"1423719-30-5",{"v":11,"d":"11.00"},{"v":24.5,"d":"24.50"},"<1","N/A","https://www.selleckchem.com/products/bi-1015550.html","C20H25ClN6O2S","free base","N/A","OCC1(CCC1)NC2=C3C(=NC(=N2)N4CCC(CC4)C5=NC=C(Cl)C=N5)CC[S]3=O",1.969,5,2,5]
["E1411","Tuvusertib","h3","L3800-47","in 10mM DMSO","N/A","N/A","Phase 2","ATM/ATR","DNA Damage/DNA Repair","Tuvusertib (M1774, ATR inhibitor 1) is a potent ATR inhibitor, which exhibits anti-proliferative and anti-tumor effects in cancer cell lines.",370.32,"1613200-51-3",{"v":12,"d":"12.00"},{"v":32.4,"d":"32.40"},"<1","N/A","https://www.selleckchem.com/products/tuvusertib.html","C16H12F2N8O","free base","M1774, ATR inhibitor 1","C[N]1C=NC=C1C2=C(F)C=NC=C2NC(=O)C3=C4N=CC(=C[N]4N=C3N)F",-0.157,5,2,3]
["E2866","Sodium tetradecyl sulfate","c4","L3800-47","in 10mM DMSO","FDA;HMA;NDC;DMF","N/A","marketed","Others","Others","Sodium tetradecyl sulfate, a detergent sclerosant, is widely used agent for esophageal varices and varicose veins.",317.44,"1191-50-0 ",{"v":63,"d":"63.00"},198.46,{"v":63,"d":"63.00"},198.46,"https://www.selleckchem.com/products/sodium-tetradecyl-sulfate.html","C14H30O4S.Na","sodium tetradecyl sulfate","N/A","[Na;v0].CCCCCCCCCCCCCCO[S](O)(=O)=O",5.322,1,0,14]
["E2868","Naloxegol Oxalate","d4","L3800-47","in 10mM DMSO","FDA","N/A","marketed","Opioid Receptor","Neuronal Signaling","Naloxegol oxalate (NKTR-118 oxalate) is a μ-opioid-receptor antagonist with a Ki of 33.8 nM. Naloxegol oxalate inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation.",741.82,"1354744-91-4",{"v":100,"d":"100.00"},{"v":134.8,"d":"134.80"},{"v":100,"d":"100.00"},{"v":134.8,"d":"134.80"},"https://www.selleckchem.com/products/naloxegol-oxalate.html","C34H53NO11.C2H2O4","oxalate","N/A","COCCOCCOCCOCCOCCOCCOCCOC1CCC2(O)C3CC4=C5C(=C(O)C=C4)OC1C25CCN3CC=C.OC(=O)C(O)=O",-2.512,11,1,25]
["E2873","Laropiprant","g4","L3800-47","in 10mM DMSO","DMF; EMA","N/A","Phase 3","Prostaglandin Receptor","GPCR & G Protein","Laropiprant is a potent and selective prostaglandin D2 (DP) receptor antagonist with a Ki value of 0.57 nM.",{"v":435.9,"d":"435.90"},"571170-77-9",{"v":87,"d":"87.00"},199.59,"<1","N/A","https://www.selleckchem.com/products/laropiprant.html","C21H19CIFNO4S","free base","N/A","C[S](=O)(=O)C1=C2[N](CC3=CC=C(Cl)C=C3)C4=C(CCC4CC(O)=O)C2=CC(=C1)F",4.876,3,0,5]
["E2876","pemafibrate","b5","L3800-47","in 10mM DMSO","PMDA","N/A","marketed","PPAR","Metabolism","Pemafibrate(K-877) is a selective agonist of peroxisome proliferator-activated receptor (PPAR) α with an IC50  of 10 µM.",490.55,"848259-27-8",{"v":98,"d":"98.00"},199.78,"<1","N/A","https://www.selleckchem.com/products/pemafibrate.html","C28H30N2O6","free base","K-877","CCC(OC1=CC=CC(=C1)CN(CCCOC2=CC=C(OC)C=C2)C3=NC4=CC=CC=C4O3)C(O)=O",5.794,6,0,13]
["E2891","Dxd","f5","L3800-47","in 10mM DMSO","N/A","N/A","Phase 2","Topoisomerase","DNA Damage/DNA Repair","Dxd(Exatecan derivative for ADC) is a potent  DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM.",493.48,"1599440-33-1",{"v":8,"d":"8.00"},16.21,"<1","N/A","https://www.selleckchem.com/products/dxd.html","C26H24FN3O6","free base","Exatecan derivative for ADC","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C5C(CCC6=C5C(=CC(=C6C)F)N=C34)NC(=O)CO)C2=O",1.452,5,2,3]
["E2939","Didox","a6","L3800-47","in 10mM DMSO","N/A","N/A","Phase 2","DNA/RNA Synthesis","Cell Cycle","Didox (3,4-dihydroxy-benzohydroxamic acid)  is a synthetic ribonucleotide reductase (RR) inhibitor derived from polyhydroxy-substituted benzohydroxamic acid. Didox inhibits proliferation of tamoxifen-resistant breast cancer cells.",169.14,"69839-83-4",{"v":34,"d":"34.00"},201.02,{"v":34,"d":"34.00"},201.02,"https://www.selleckchem.com/products/didox.html","C7H7NO4","free base","3,4-dihydroxy-benzohydroxamic acid","ONC(=O)C1=CC(=C(O)C=C1)O",{"v":0.36,"d":"0.360"},1,3,1]
["E2968","Zinc sulfate heptahydrate","f6","L3800-47","in 10mM DMSO","FDA; NMPA; PMDA","N/A","marketed","Others","Others","Zinc sulfate heptahydrate is a hydrate that is the heptahydrate form of zinc sulfate. Zinc sulfate heptahydrate is a dietary supplement used for zinc deficiency and can also accelerate the rate of healing. It is also used in prepration of zinc tris(thiourea) sulphate (ZTS), a semiorganic nonlinear optic (NLO) material that may be useful in laser fusion experiments and in second-harmonic-generation (SHG) devices.",289.58,"7446-20-0",{"v":36,"d":"36.00"},124.32,{"v":36,"d":"36.00"},124.32,"https://www.selleckchem.com/products/zinc-sulfate-heptahydrate.html","H2O4S.7H2O.Zn","zinc sulfate","N/A","O.[Zn].O[S](O)(=O)=O",-0.815,0,0,0]
["E4013","Melanin","a7","L3800-47","in 10mM DMSO","NDC; DMF","N/A","marketed","Others","Others","Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation.",318.28,"8049-97-6",{"v":64,"d":"64.00"},201.08,"<1","N/A","https://www.selleckchem.com/products/melanin.html","N/A","free base","N/A","N/A","N/A","N/A","N/A","N/A"]
["S1423","Dobutamine HCl","d7","L3800-47","in 10mM DMSO","FDA;NDC;PMDA;DMF","N/A","Phase 4","Adrenergic Receptor","Neuronal Signaling","Dobutamine(Dobutrex) hydrochloride is a selective potent agonist of β1-AR (β-1 adrenergic receptor) and exhibits weak activity at α1-AR and β2-AR. Dobutamine is a sympathomimetic compound that effectively restores blood pressure in hypotensive dogs and human patients by improving myocardial contractility and increasing cardiac output (CO).",337.84,"49745-95-1",{"v":68,"d":"68.00"},201.28,"<1","N/A","https://www.selleckchem.com/products/Dobutamine-hydrochloride.html","C18H23NO3&middot;HCl","hydrochloride","Dobutrex","Cl.CC(CCC1=CC=C(O)C=C1)NCCC2=CC(=C(O)C=C2)O",4.083,0,4,7]
["S7354","Filanesib hydrochloride","e7","L3800-47","in 10mM DMSO","N/A","N/A","Phase 2","Kinesin","Cytoskeletal Signaling","Filanesib (ARRY-520) hydrochloride is a kinesin spindle protein (KSP) inhibitor that blocks the separation of centrosomes and assembly of spindles in the early stage of cell mitosis, and cell proliferation.",456.94,"1385020-40-5",{"v":91,"d":"91.00"},199.15,{"v":91,"d":"91.00"},199.15,"https://www.selleckchem.com/products/filanesib.html","C20H22F2N4O2S.ClH","hydrochloride","ARRY-520 hydrochloride","Cl.CON(C)C(=O)N1N=C(SC1(CCCN)C2=CC=CC=C2)C3=C(F)C=CC(=C3)F",3.854,3,1,6]
["S9633","GS-6207","a8","L3800-47","in 10mM DMSO","N/A","N/A","Phase 2","HIV Protease","Microbiology","GS-6207 (Lenacapavir) is a HIV-1 capsid inhibitor. It shows anti-HIV activity with an EC50 of 0.1 nM in MT-4 cells.",968.29,"2189684-44-2",{"v":100,"d":"100.00"},103.27,"<1","N/A","https://www.selleckchem.com/products/gs-6207.html","C39H32ClF10N7O5S2","chloride","Lenacapavir","CC(C)(C#CC1=NC(=C(C=C1)C2=C3[N](CC(F)(F)F)N=C(N[S](C)(=O)=O)C3=C(Cl)C=C2)C(CC4=CC(=CC(=C4)F)F)NC(=O)C[N]5N=C(C6=C5C(F)(F)C7CC67)C(F)(F)F)[S](C)(=O)=O",8.496,8,2,15]
["E0109","Fezolinetant","c8","L3800-47","in 10mM DMSO","FDA","N/A","Phase 2","Neurokinin Receptor","GPCR & G Protein","Fezolinetant (ESN-364) is a potential antagonist of the neurokinin 3 receptor (NK3R). It interrupts pulsatile lh secretion and moderates levels of ovarian hormones throughout the menstrual cycle.",358.39,"1629229-37-3",{"v":72,"d":"72.00"},{"v":200.9,"d":"200.90"},"<1","N/A","https://www.selleckchem.com/products/fezolinetant.html","C₁₆H₁₅FN₆OS","free base","ESN-364","CC1N(CC[N]2C1=NN=C2C3=NC(=NS3)C)C(=O)C4=CC=C(F)C=C4",1.714,5,0,2]
["E1435","Tinengotinib","f8","L3800-47","in 10mM DMSO","N/A","N/A","Phase 3","Aurora Kinase","Cell Cycle","Tinengotinib (TT-00420) is a novel multiple kinase inhibitor that strongly inhibits Aurora A/B with IC50 values of 1.2/3.3 nM respectively. It also exhibits potent inhibitory activity on FGFR1/2/3, VEGFR1, JAK1/2, and CSF1R and can be used to treat several prominent signaling pathways in triple-negative breast cancer(TNBC).",394.86,"2230490-29-4",{"v":79,"d":"79.00"},200.07,"<1","N/A","https://www.selleckchem.com/products/tinengotinib.html","C20H19ClN6O","free base","TT-00420","CC1=C2N=C(C3=C(Cl)C=CC=C3)C4=CN=C(C=C4NC2=N[NH]1)N5CCOCC5",3.822,4,2,2]
["E1578","garsorasib (D-1553 )","a9","L3800-47","in 10mM DMSO","N/A","N/A","Phase 2","Ras","GPCR & G Protein","Garsorasib (D-1553 ) is a potent and selective oral KRAS<sup>G12C</sup> inhibitor with antitumor activity. It has the potential to treat KRAS G12C-mutated non-small cell lung cancer (NSCLC).",598.65,"2559761-14-5",{"v":100,"d":"100.00"},167.04,"<1","N/A","https://www.selleckchem.com/products/d-1553.html","C32H32F2N8O2","free base","N/A","CC1CN(C(C)CN1C(=O)C=C)C2=NC(=O)N(C3=NC(=C(F)C=C23)C4=C(F)C=CC=C4N)C5=C(N=CN=C5C6CC6)C7CC7",4.785,6,1,6]
["E1657","Gamcemetinib (CC-99677)","e9","L3800-47","in 10mM DMSO","N/A","N/A","Phase 2","MAPKAPK2","MAPK","Gamcemetinib (CC-99677,BMS-986371) is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) (MAPKAPK2 (MK2)) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM).",469.95,"1887069-10-4",{"v":94,"d":"94.00"},200.02,"<1","N/A","https://www.selleckchem.com/products/cc-99677.html","C22H20ClN5O3S","free base","BMS-986371","CCOCC1=CN=C(Cl)N=C1OC2=CC=C3C(=N2)C=CC4=C3C5=C(S4)C(=O)NC(C)CN5",{"v":4.25,"d":"4.250"},6,2,5]
["E1709","Fialuridine","h9","L3800-47","in 10mM DMSO","N/A","N/A","Phase 2","CMV","Microbiology","Fialuridine(FIAU, DRG-0098, NSC 678514) is a nucleoside analog with antiviral activity. It blocks DNAsynthesis in human cytomegalovirus and hepatitis B, as well as herpes simplex.",372.09,"69123-98-4",{"v":74,"d":"74.00"},198.88,"<1","N/A","https://www.selleckchem.com/products/fialuridine.html","C9H10FIN2O5","free base","FIAU; DRG-0098; NSC 678514","OCC1OC(C(F)C1O)N2C=C(I)C(=O)NC2=O",-1.228,3,3,2]
["E1743","VX-561(CTP-656, Deutivacaftor)","c10","L3800-47","in 10mM DMSO","N/A","N/A","Phase 2","CFTR","Transmembrane Transporters","VX-561 (Ivacaftor-D9, CTP-656, Deutivacaftor), a deuterated ivacaftor analog, is a potent CFTR modulator and exhibits an EC50 value of 255 nM for CFTR potentiation in G551D/F508del HBE cells.",401.55,"1413431-07-8",{"v":80,"d":"80.00"},199.23,"<1","N/A","https://www.selleckchem.com/products/vx-561.html","C24H19D9N2O3","free base","Ivacaftor-D9, CTP-656, Deutivacaftor","C(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C1=CC(=C(NC(=O)C2=CNC3=CC=CC=C3C2=O)C=C1O)C(C)(C)C)([2H])([2H])[2H]",4.516,2,3,7]
["E2363","Etrasimod(APD334)","d10","L3800-47","in 10mM DMSO","N/A","N/A","Phase 3","S1P Receptor","GPCR & G Protein","Etrasimod(APD334) is a potent, selective and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor with an EC50 value of 1.88 nM in CHO cells.",457.49,"1206123-37-6",{"v":92,"d":"92.00"},{"v":201.1,"d":"201.10"},"<1","N/A","https://www.selleckchem.com/products/apd334.html","C26H26F3NO3","free base","APD334","OC(=O)CC1CCC2=C1[NH]C3=CC=C(OCC4=CC(=C(C=C4)C5CCCC5)C(F)(F)F)C=C23",6.935,2,1,7]
["E2985","Capadenoson","g10","L3800-47","in 10mM DMSO","N/A","N/A","Phase 2","Adenosine Receptor","GPCR & G Protein","Capadenoson (BAY 68-4986) is an orally bioavailable, non-nucleoside partial adenosine A1 receptor agonist that exhibits an anti-ischemic effect.",520.03,"544417-40-5",{"v":50,"d":"50.00"},96.15,"<1","N/A","https://www.selleckchem.com/products/capadenoson.html","C25H18ClN5O2S2","free base","BAY 68-4986","NC1=NC(=C(C#N)C(=C1C#N)C2=CC=C(OCCO)C=C2)SCC3=CSC(=N3)C4=CC=C(Cl)C=C4",5.116,3,2,8]
["E4466","Saquinavir Mesylate","c11","L3800-47","in 10mM DMSO","EMA; FDA","N/A","Phase 3","HIV Protease","Proteases","Saquinavir mesylate (Ro 31-8959/003) is a potent inhibitor of HIV Protease used in antiretroviral therapy. It blocks proteolysis of polyproteins containing either wild-type or single-chain dimer retroviral proteinase (PR).",766.95,"149845-06-7",{"v":50,"d":"50.00"},65.19,"<1","N/A","https://www.selleckchem.com/products/saquinavir-mesylate.html","C38H50N6O5.CH4O3S","mesylate salt","Ro 31-8959/003","CC(C)(C)NC(=O)C1CC2CCCCC2CN1CC(O)C(CC3=CC=CC=C3)NC(=O)C(CC(N)=O)NC(=O)C4=NC5=C(C=CC=C5)C=C4.C[S](O)(=O)=O",3.253,5,5,13]
["E4474","Infigratinib Phosphate","f11","L3800-47","in 10mM DMSO","FDA","N/A","Phase 3","FGFR","Angiogenesis","Infigratinib Phosphate (NVP-BGJ398 phosphate) is the phosphate salt form of infigratinib, an orally bioavailable pan-inhibitor of human  fibroblast growth factor receptors (FGFRs)  with IC50 of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for  FGFR1, FGFR2, FGFR3, and FGFR4 respectively. It also has potential antiangiogenic, antineoplastic and antitumor activities.",658.47,"1310746-10-1",{"v":100,"d":"100.00"},151.87,"<1","N/A","https://www.selleckchem.com/products/infigratinib-phosphate.html","C26H31Cl2N7O3.H3O4P","Phosphate","NVP-BGJ398 phosphate","CCN1CCN(CC1)C2=CC=C(NC3=CC(=NC=N3)N(C)C(=O)NC4=C(Cl)C(=CC(=C4Cl)OC)OC)C=C2.O[P](O)(O)=O",4.874,5,2,8]
["S3575","Zandelisib","a2","L3800-48","in 10mM DMSO","N/A","N/A","Phase 2","PI3K","PI3K/Akt/mTOR","Zandelisib(ME-401; PWT-143) is an orally bioavailable inhibitor of the phosphatidylinositide 3-kinase (PI3K). It selectively inhibits the delta isoform of PI3K (p110δ)  and prevents the activation of the PI3K/AKT signaling pathway with an IC50 of 3.5 nM. It functions as an antineoplastic agent.",576.68,"1401436-95-0",{"v":13,"d":"13.00"},22.54,"<1","N/A","https://www.selleckchem.com/products/zandelisib.html","C31H38F2N8O","free base","ME-401; PWT-143","CN1CCC(CC1)C2=C(CC(C)(C)NC3=NC(=NC(=N3)[N]4C(=NC5=CC=CC=C45)C(F)F)N6CCOCC6)C=CC=C2",6.503,5,1,8]
["S9969","RMC-4630","e2","L3800-48","in 10mM DMSO","N/A","N/A","Phase 2","Microtubule Associated","Cytoskeletal Signaling","RMC-4630 (SSE15206) is an inhibitor of microtubule polymerization with a GI50 of 197 nM in HCT116 cells. It can overcome multidrug resistance and cause aberrant mitosis, resulting in G2/M arrest due to incomplete spindle formation in cancer cells.",450.99,"2172652-48-9",{"v":45,"d":"45.00"},99.78,"<1","N/A","https://www.selleckchem.com/products/rmc-4630.html","C20H27ClN6O2S","Chloride","SSE15206","CC1OCC2(CCN(CC2)C3=NC(=C(SC4=CC=NC(=C4Cl)N)N=C3CO)C)C1N",1.624,4,3,4]
["E1280","Ubrogepant","h2","L3800-48","in 10mM DMSO","FDA","N/A","Phase 3","CGRP Receptor","GPCR & G Protein","Ubrogepant (MK-1602) is an antagonist of human calcitonin gene-related peptide receptor (CGRP). It potently blocks human α–CGRP–stimulated cAMP responses with an IC50 of 0.081 nM in human CGRP receptor-expressing HEK293 cells.",549.54,"1374248-77-7",{"v":100,"d":"100.00"},181.97,"<1","N/A","https://www.selleckchem.com/products/ubrogepant.html","C29H26F3N5O3","free base","MK-1602","CC1C(CC(NC(=O)C2=CN=C3CC4(CC3=C2)C(=O)NC5=NC=CC=C45)C(=O)N1CC(F)(F)F)C6=CC=CC=C6",2.897,5,2,5]
["E1483","IK-930","c3","L3800-48","in 10mM DMSO","N/A","N/A","Phase 1","TEAD","Hippo","IK-930 is a selective, small-molecule inhibitor of TEAD that prevents palmitate binding and thereby disrupts aberrant TEAD-dependent transcription. IK-930 demonstrates antitumor activity in mouse xenograft models with Hippo pathway genetic alterations.",424.44,"2563892-44-2",{"v":85,"d":"85.00"},200.26,"<1","N/A","https://www.selleckchem.com/products/ik-930.html","C19H19F3N4O2S","free base","N/A","CN[S](=O)(=O)C1=CC(=C(NCC2=CC=C(C=C2)C(F)(F)F)C=C1)C3=C[N](C)C=N3",3.115,3,2,7]
["E1486","Zamaporvint (RXC004)","d3","L3800-48","in 10mM DMSO","N/A","N/A","Phase 2","Wnt/beta-catenin","Stem Cells & Wnt","Zamaporvint (RXC004) is an orally active and selective inhibitor of Wnt. It targets membrane-bound o-acyltransferase Porcupine and inhibits Wnt ligand palmitoylation, secretion, and pathway activation. RXC004 exhibits potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines and possesses multiple antitumor mechanisms.",439.39,"1900754-56-4",{"v":88,"d":"88.00"},200.28,"<1","N/A","https://www.selleckchem.com/products/rxc004.html","C21H16F3N7O","free base","N/A","CC1=C(N=C[N]1CC(=O)NC2=CC=C(C=N2)C3=NC=CN=C3)C4=CC=NC(=C4)C(F)(F)F",1.906,6,1,6]
["E1517","ZEN-3694","g3","L3800-48","in 10mM DMSO","N/A","N/A","Phase 2","Epigenetic Reader Domain","Epigenetics","ZEN-3694 is an orally bioavailable  bromodomain extraterminal inhibitor (BETi)  that leads to down-regulation of expression of AR-signaling in metastatic castrationresistant prostate cancer (mCRPC) models.",333.39,"1643947-30-1",{"v":67,"d":"67.00"},200.97,"<1","N/A","https://www.selleckchem.com/products/zen-3694.html","C19H19N5O","free base","N/A","CNC1=NC2=NC=C(C=C2[N]1CC3=CC=CC=C3)C4=C(C)ON=C4C",{"v":2.93,"d":"2.930"},4,1,4]
["S1634","Acetaminophen","c4","L3800-48","in 10mM DMSO","NDC, PMDA, DMF","N/A","Marketed","COX","Neuronal Signaling","Acetaminophen is a COX inhibitor for COX-1 and COX-2 with IC50 of 113.7 μM and 25.8 μM, respectively.",151.16,"103-90-2",{"v":30,"d":"30.00"},198.47,{"v":13,"d":"13.00"},{"v":86,"d":"86.00"},"https://www.selleckchem.com/products/acetaminophen.html","C8H9NO2","Free Base","Paracetamol, Tylenol, APAP","CC(=O)Nc1ccc(O)cc1",0.708,1,2,1]
["E1796","Dimethindene maleate","f4","L3800-48","in 10mM DMSO","HMA","BP2024;EP11.0;Martindale: The Complete Drug Reference","Marketed","Histamine Receptor","Neuronal Signaling","Dimethindene maleate is a selective antagonist of <b>histamine H1</b> and exhibits antihistamine effects. It suppresses the cromakalim-induced/glibenclamide-sensitive K+ currents in a concentration-dependent and reversible manner.",408.49,"3614-69-5",{"v":82,"d":"82.00"},200.74,{"v":9,"d":"9.00"},22.03,"https://www.selleckchem.com/products/dimethindene-maleate.html","C20H24N2.C4H4O4","maleate","N/A","[CH3:2][CH:1]([C:17]1=[CH:18][CH:20]=[CH:22][CH:21]=[N:19]1)[C:8]2=[C:10]([CH2:3][CH2:4][N:5]([CH3:6])[CH3:7])[CH2:13][C:11]3=[CH:14][CH:16]=[CH:15][CH:12]=[C:9]23.[OH:27][C:25](=[O:28])\\[CH:23]=[CH:24]/[C:26]([OH:29])=[O:30]",1.055,3,{"v":0,"d":"0.000"},7]
["P1094","Degarelix acetate","a5","L3800-48","in 10mM DMSO","EMA,FDA,DMF,PMDA,CFDA","Martindale: The Complete Drug Reference","Marketed","Others","Endocrinology & Hormones","Degarelix acetate (ASP-3550 acetate) is a potent and long-acting <b>luteinizing hormone-releasing hormone (LHRH)</b> antagonist.","1632.26(free base)","934016-19-0",{"v":100,"d":"100.00"},61.26,{"v":100,"d":"100.00"},61.26,"https://www.selleckchem.com/products/degarelix-acetate.html","C82H103ClN18O16.C2H4O2","acetate","N/A","[CH3:19][CH:15]([CH3:20])[CH2:12][CH:8]([NH:11][C:14](=[O:18])[CH:17]([CH2:22][C:78]1=[CH:79][CH:81]=[C:83]([NH:63][C:64]([NH2:65])=[O:66])[CH:82]=[CH:80]1)[NH:23][C:26](=[O:28])[CH:27]([CH2:29][C:84]2=[CH:85][CH:87]=[C:89]([NH:67][C:68](=[O:69])[CH:90]3[CH2:91][C:93](=[O:70])[NH:95][C:94](=[O:71])[NH:92]3)[CH:88]=[CH:86]2)[NH:30][C:31](=[O:33])[CH:32]([CH2:35][OH:37])[NH:34][C:36](=[O:39])[CH:38]([CH2:40][C:96]4=[CH:98][N:100]=[CH:101][CH:99]=[CH:97]4)[NH:41][C:42](=[O:44])[CH:43]([CH2:45][C:102]5=[CH:103][CH:105]=[C:107]([Cl:72])[CH:106]=[CH:104]5)[NH:46][C:47](=[O:49])[CH:48]([CH2:50][C:108]6=[CH:109][C:111]7=[C:113]([CH:115]=[CH:117][CH:116]=[CH:114]7)[CH:112]=[CH:110]6)[NH:51][C:52]([CH3:53])=[O:54])[C:6](=[O:9])[NH:4][CH:2]([CH2:5][CH2:7][CH2:10][CH2:13][NH:16][CH:21]([CH3:24])[CH3:25])[C:1](=[O:3])[N:73]8[CH2:75][CH2:77][CH2:76][CH:74]8[C:55](=[O:57])[NH:56][CH:58]([CH3:60])[C:59]([NH2:61])=[O:62]",1.49,16,{"v":17,"d":"17.000"},41]
["S1037","Perifosine (KRX-0401)","a2","L3800-49","in 10mM Water","DMF","N/A","Phase 2","Akt","PI3K/Akt/mTOR","Perifosine (KRX-0401, NSC639966, D21266) is a novel Akt inhibitor with IC50 of 4.7 μM in MM.1S cells, targets pleckstrin homology domain of Akt. Phase 3.",461.66,"157716-52-4","<1","N/A",{"v":8,"d":"8.00"},17.33,"http://selleckchem.com/products/Perifosine.html","C25H52NO4P","free base","NSC639966, D21266","CCCCCCCCCCCCCCCCCCO[P]([O-])(=O)OC1CC[N+](C)(C)CC1",4.607,2,0,20]
["S1149","Gemcitabine (LY-188011) HCl","d2","L3800-49","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","Marketed","Autophagy,DNA/RNA Synthesis,Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Gemcitabine (LY-188011, NSC 613327) HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.",299.66,"122111-03-9","<1","N/A",{"v":19,"d":"19.00"},63.41,"http://selleckchem.com/products/Gemcitabine-Hydrochloride(Gemzar).html","C9H11F2N3O4.HCI","Hydrochloride","NSC 613327,LY-188011 HCl","Cl.NC1=NC(=O)N(C=C1)C2OC(CO)C(O)C2(F)F",-1.012,3,3,2]
["S1311","Pamidronate Disodium","e2","L3800-49","in 10mM Water","FDA,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP39-NF34","N/A","Others","Others","Pamidronate Disodium (CGP 23339AE) is a nitrogen containing bisphosphonate, used to prevent osteoporosis.",279.03,"57248-88-1","<1","N/A",{"v":56,"d":"56.00"},{"v":200.7,"d":"200.70"},"http://selleckchem.com/products/Pamidronate-Disodium.html","C3H9NNa2O7P2","Disodium salt","CGP 23339AE","[Na+].[Na+].NCCC(O)([P](O)([O-])=O)[P](O)([O-])=O",-5.016,0,1,4]
["S1345","Granisetron HCl","h2","L3800-49","in 10mM Water","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,EP9.1,BP2017","Marketed","5-HT Receptor","Neuronal Signaling","Granisetron is a serotonin 5-HT3 receptor antagonist,used to treat chemotherapy-induced nausea and vomiting.",348.87,"107007-99-8",{"v":1,"d":"1.00"},2.87,{"v":69,"d":"69.00"},197.78,"http://selleckchem.com/products/Granisetron-Hydrochloride.html","C18H24N4O.HCl","Hydrochloride","N/A","Cl.CN1C2CCCC1CC(C2)NC(=O)C3=N[N](C)C4=CC=CC=C34",2.783,2,1,2]
["S1384","Mizoribine","c3","L3800-49","in 10mM Water","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17","Marketed","DNA/RNA Synthesis,HCV","DNA Damage/DNA Repair","Mizoribine (Bredinin, NSC 289637,HE 69) is an imidazole nucleoside and an immunosuppressant that inhibits HCV RNA replication with IC50 of ~ 100 μM for anti-HCV activity. Mizoribine is a selective inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH) and guanosine monophosphate synthetase. Mizoribine also inhibits SARS-CoV.",259.22,"50924-49-7",{"v":1,"d":"1.00"},3.86,{"v":51,"d":"51.00"},196.74,"http://selleckchem.com/products/Mizoribine.html","C9H13N3O6","free base","Bredinin, NSC 289637,HE 69","NC(=O)C1=C(O)[N](C=N1)C2OC(CO)C(O)C2O",-2.409,3,5,3]
["S1494","Ralimetinib (LY2228820) dimesylate","g3","L3800-49","in 10mM Water","N/A","N/A","Phase 2","p38 MAPK","MAPK","Ralimetinib (LY2228820) dimesylate is a novel and potent inhibitor of p38 MAPK with IC50 of 7 nM in a cell-free assay, does not alter p38 MAPK activation. Phase 1/2.",612.74,"862507-23-1",{"v":4,"d":"4.00"},6.53,{"v":100,"d":"100.00"},{"v":163.2,"d":"163.20"},"http://selleckchem.com/products/LY2228820.html","C24H29FN6.2CH4O3S","dimesylate","N/A","CC(C)(C)C[N]1C(=NC2=CC=C(N=C12)C3=C(N=C([NH]3)C(C)(C)C)C4=CC=C(F)C=C4)N.C[S;v6](O)(=O)=O",5.117,3,2,5]
["S1518","Ibuprofen Lysine","b4","L3800-49","in 10mM Water","FDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia","Marketed","COX","Neuronal Signaling","Ibuprofen Lysine is a non-steroidal anti-inflammatory drug.",352.47,"57469-77-9","<1","N/A",{"v":71,"d":"71.00"},201.44,"http://selleckchem.com/products/Ibuprofen-Lysine(Motrin).html","C19H32N2O4","Lysine","N/A","CC(C)CC1=CC=C(C=C1)C(C)C(O)=O.NCCCCC(N)C(O)=O",-2.112,2,2,9]
["S1648","Cytarabine (U-19920A)","e4","L3800-49","in 10mM Water","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","Marketed","Apoptosis related,Autophagy,DNA/RNA Synthesis,Nucleoside Analog/Antimetabolite","DNA Damage/DNA Repair","Cytarabine (Cytarabin, Ara-C, Arabinofuranosyl Cytidine, Cytosine β-D-arabinofuranoside, Cytosine arabinoside, NSC 63878, NSC 287459,U-19920A) is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM in wild-type CCRF-CEM cells. Cytarabine induces autophagy and apoptosis.",243.22,"147-94-4",{"v":1,"d":"1.00"},4.11,{"v":48,"d":"48.00"},197.35,"http://selleckchem.com/products/Cytarabine(Cytosar-U).html","C9H13N3O5","free base","Cytarabin,Ara-C,Arabinofuranosyl Cytidine,Cytosine β-D-arabinofuranoside,Cytosine arabinoside,NSC 63878,NSC 287459,U-19920A","NC1=NC(=O)N(C=C1)C2OC(CO)C(O)C2O",-2.396,3,4,2]
["S1857","Etidronate","a5","L3800-49","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,JP17,BP2017,USP39-NF34","N/A","phosphatase","Metabolism","Etidronate is a non-aminobisphosphonate, show protein tyrosine phosphatase (PTP) inhibitory activity, used for the treatment of Paget's disease and the prevention of heterotopic ossification.",206.03,"2809-21-4","<1","N/A",{"v":41,"d":"41.00"},{"v":199,"d":"199.00"},"http://selleckchem.com/products/etidronate-didronel.html","C2H8O7P2","free base","N/A","CC(O)([P](O)(O)=O)[P](O)(O)=O",-0.701,0,0,2]
["S1984","Ticlopidine HCl","d5","L3800-49","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","Marketed","P2 Receptor","Neuronal Signaling","Ticlopidine HCl is an P2 receptor inhibitor against ADP-induced platelet aggregation with IC50 of ~2 μM.",300.25,"53885-35-1",{"v":1,"d":"1.00"},3.33,{"v":4,"d":"4.00"},13.32,"http://selleckchem.com/products/ticlopidine-hydrochloride.html","C14H14ClNS.HCl","Hydrochloride","N/A","Cl.ClC1=C(CN2CCC3=C(C2)C=CS3)C=CC=C1",4.275,0,0,2]
["S1985","ATP disodium","e5","L3800-49","in 10mM Water","DMF,NDC","N/A","N/A","Others","Others","ATP Disodium (Adenosine-Triphosphate disodium, ATP disodium salt, Adenosine 5'-triphosphate) is a disodium salt form of adenosine-triphosphate which is a multifunctional nucleoside triphosphate.",551.14,"987-65-5","<1","N/A",{"v":100,"d":"100.00"},181.44,"http://selleckchem.com/products/atp-Adenosine-Triphosphate.html","C10H14N5O13P3.2Na","Disodium Salt","Adenosine-Triphosphate disodium, ATP disodium salt, Adenosine 5'-triphosphate","[Na+].[Na+].NC1=NC=NC2=C1N=C[N]2C3OC(CO[P](O)(=O)O[P]([O-])(=O)O[P](O)([O-])=O)C(O)C3O",-5.474,7,3,8]
["S1999","Sodium butyrate","h5","L3800-49","in 10mM Water","DMF","USP39-NF34","N/A","Apoptosis related,Autophagy,HDAC","Epigenetics","Sodium butyrate (NaB, Butanoic acid sodium salt), sodium salt of butyric acid, is a histone deacetylase inhibitor and competitively binds to the zinc sites of class I and II histone deacetylases (HDACs). Sodium butyrate (NaB) inhibits cell cycle progression, promotes differentiation, and induces apoptosis and autophagy in several types of cancer cells.",110.09,"156-54-7","<1","N/A",{"v":22,"d":"22.00"},199.84,"http://selleckchem.com/products/Sodium-butyrate.html","C4H7NaO2","Sodium Salt","NaB, Butanoic acid sodium salt","[Na+].CCCC([O-])=O",-0.556,0,0,2]
["S2076","Lisinopril dihydrate","c6","L3800-49","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017,IP2010","Marketed","ACE,RAAS","Endocrinology & Hormones","Lisinopril dihydrate(MK-521 dihydrate) is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes.",441.52,"83915-83-7","<1","N/A",{"v":20,"d":"20.00"},49.32,"http://selleckchem.com/products/lisinopril-zestril.html","C21H35N3O7","free base","MK-521 dihydrate","NCCCCC(NC(CCC1=CC=CC=C1)C(O)=O)C(=O)N2CCCC2C(O)=O",-3.673,3,2,12]
["S2416","Chondroitin sulfate","g6","L3800-49","in 10mM Water","DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","Marketed","NF-κB","NF-κB","Chondroitin sulfate (CS) is a major component of the extracellular matrix (ECM) of many connective tissues, including cartilage, bone, skin, ligaments and tendons. It reduces the IL-1β-induced nuclear factor-kB (NF-κB) translocation in chondrocytes in vitro.",489.45,"9007-28-7","N/A","N/A",{"v":97,"d":"97.00"},198.18,"http://selleckchem.com/products/chondroitin-sulfate.html","(C14H21NO14S)n","sulfate","N/A","COC1OC(CO[S](O)(=O)=O)C(O)C(OC2OC(C(C)C(O)C2O)C(O)=O)C1NC(C)=O",-2.447,7,4,8]
["S2507","Salbutamol Sulfate","b7","L3800-49","in 10mM Water","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017","Marketed","Adrenergic Receptor","Neuronal Signaling","Salbutamol Sulfate (Albuterol, Ventolin, Aerolin, Ventorlin, Asthalin, Asthavent) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 µM.",337.39,"51022-70-9","<1","N/A",{"v":68,"d":"68.00"},201.55,"http://selleckchem.com/products/Salbutamol-sulfate(Albuterol).html","C13H21NO3.H2SO4","Sulfate","Albuterol, Ventolin, Aerolin, Ventorlin, Asthalin, Asthavent","CC(C)(C)NCC(O)C1=CC=C(O)C(=C1)CO.O[S](O)(=O)=O",0.334,0,4,5]
["S2539","Lomefloxacin HCl","f7","L3800-49","in 10mM Water","FDA,DMF,CFDA,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics","Microbiology","Lomefloxacin HCl is a hydrochloride salt of lomefloxacin and is a fluoroquinolone antibiotic.",387.81,"98079-52-8",{"v":1,"d":"1.00"},2.58,{"v":6,"d":"6.00"},15.47,"http://selleckchem.com/products/Lomefloxacin-hydrochloride-Maxaquin.html","C17H19F2N3O3.HCl","Hydrochloride","N/A","Cl.CCN1C=C(C(O)=O)C(=O)C2=CC(=C(N3CCNC(C)C3)C(=C12)F)F",-0.446,2,1,3]
["S2568","Neomycin sulfate","a8","L3800-49","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP35-NF30","Marketed","Antibiotics,Antibiotics for Mammalian Cell Culture,Antineoplastic and Immunosuppressive Antibiotics,Bacterial,Selection Antibiotics for Transfected Cell","Microbiology","Neomycin sulfate(Framycin sulfate) is an aminoglycoside antibiotic, used to treat bacteria infections.",712.72,"28002-70-2 ,1405-10-3","<1","N/A",{"v":143,"d":"143.00"},200.64,"http://selleckchem.com/products/Neomycin-sulfate.html","C23H46N6O13.H2SO4","Sulfate","Framycin sulfate","NCC1OC(OC2C(N)CC(N)C(O)C2OC3OC(CO)C(OC4OC(CN)C(O)C(O)C4N)C3O)C(N)C(O)C1O.O[S](O)(=O)=O",-9.566,6,13,9]
["S2877","L-NAME HCl","d8","L3800-49","in 10mM Water","N/A","N/A","Phase 2","NOS","Immunology & Inflammation","L-NAME HCl (NG-Nitroarginine methyl ester, N-Nitro-L-arginine methylester) is a nonselective inhibitor of nitric oxide synthetases (NOS) for nNOS (bovine), eNOS (human), and iNOS (murine), with Ki of 15 nM, 39 nM and 4.4 μM, respectively.",269.69,"51298-62-5","<1","N/A",{"v":54,"d":"54.00"},200.23,"http://selleckchem.com/products/l-name-hcl.html","C7H15N5O4.HCl","Hydrochloride","NG-Nitroarginine methyl ester, N-Nitro-L-arginine methylester","Cl.COC(=O)C(N)CCCNC(=N)N[N+]([O-])=O",1.463,2,3,9]
["S2908","Hygromycin B","e8","L3800-49","in 10mM Water","N/A","Martindale:The Extra Pharmacopoeia","N/A","Antibiotics,Antibiotics for Plant Cell Culture,Antineoplastic and Immunosuppressive Antibiotics,Bacterial,Selection Antibiotics for Transfected Cell","Microbiology","Hygromycin B (Hygrovetine), a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.",527.52,"31282-04-9","<1","N/A",{"v":100,"d":"100.00"},189.57,"http://selleckchem.com/products/hygromycin-b.html","C20H37N3O13","free base","Hygrovetine","CNC1CC(N)C(O)C(OC2OC(CO)C(O)C3OC4(OC(C(N)CO)C(O)C(O)C4O)OC23)C1O",{"v":-5.97,"d":"-5.970"},5,11,6]
["S3028","Geneticin (G418 Sulfate)","h8","L3800-49","in 10mM Water","N/A","USP42-NF37","N/A","Antibiotics,Antibiotics for Plant Cell Culture,Antineoplastic and Immunosuppressive Antibiotics,Selection Antibiotics for Transfected Cell","Microbiology","Geneticin (G418 Sulfate), an aminoglycoside antibiotic, is an elongation inhibitor of 80 S ribosomes that blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.",692.71,"108321-42-2","<1","N/A",{"v":100,"d":"100.00"},144.36,"http://selleckchem.com/products/geneticin-g418-sulfate.html","C20H40N4O10.2H2SO4","Disulfate","N/A","CNC1C(O)C(OCC1(C)O)OC2C(N)CC(N)C(OC3OC(C(C)O)C(O)C(O)C3N)C2O.O[S](O)(=O)=O.O[S](O)(=O)=O",-6.833,4,9,6]
["S3056","Miltefosine","c9","L3800-49","in 10mM Water","FDA,NDC","Martindale:The Extra Pharmacopoeia","Marketed","Akt","PI3K/Akt/mTOR","Miltefosine (Hexadecylphosphocholine) inhibits PI3K/Akt activity with ED50 of 17.2 μM and 8.1 μM in carcinoma cell lines A431 and HeLa, first oral drug for Visceral leishmaniasis, effective against both promastigotes and amastigotes.",407.57,"58066-85-6","<1","N/A",{"v":81,"d":"81.00"},198.74,"http://selleckchem.com/products/miltefosine-hexadecylphosphocholine.html","C21H46NO4P","free base","Hexadecylphosphocholine","CCCCCCCCCCCCCCCCO[P]([O-])(=O)OCC[N+](C)(C)C",3.722,2,0,20]
["S3072","(R)-baclofen","f9","L3800-49","in 10mM Water","DMF","N/A","Registered","GABA Receptor","Neuronal Signaling","(R)-baclofen (STX 209) is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.",213.66,"69308-37-8","<1","N/A",{"v":8,"d":"8.00"},37.44,"http://selleckchem.com/products/r-baclofen.html","C10H12ClNO2","free base","STX 209","NCC(CC(O)=O)C1=CC=C(Cl)C=C1",{"v":-1.06,"d":"-1.060"},1,1,4]
["S3122","Amikacin hydrate","a10","L3800-49","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.6,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","Registered","Antibiotics,Bacterial,Selection Antibiotics for Transfected Cell","Microbiology","Amikacin(BAY416651 hydrate) is an aminoglycoside antibiotic used to treat different types of bacterial infections.","585.6+x18","1257517-67-1","<1","N/A",{"v":100,"d":"100.00"},{"v":10,"d":"10.00"},"http://selleckchem.com/products/amikacin-hydrate.html","C22H43N5O13.xH2O","Hydrate","BAY416651 hydrate","O.NCCC(O)C(=O)NC1CC(N)C(OC2OC(CN)C(O)C(O)C2O)C(O)C1OC3OC(CO)C(O)C(N)C3O",{"v":0,"d":"0.000"},0,0,0]
["S3174","L-Arginine HCl (L-Arg)","e10","L3800-49","in 10mM Water","DMF,CFDA,NDC","JP17,IP2010","N/A","NOS","Immunology & Inflammation","L-Arginine(L-Arg,(S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.",210.66,"1119-34-2","<1","N/A",{"v":42,"d":"42.00"},199.37,"http://selleckchem.com/products/l-Arginine-hydrochloride.html","C6H14N4O2.HCl","HCl","(S)-(+)-Arginine hydrochloride","Cl.NC(CCCNC(N)=N)C(O)=O",-3.449,1,3,6]
["S3649","Ceftazidime","h10","L3800-49","in 10mM Water","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,JP17,BP2015,IP2010","Marketed","Anti-infection,Selection Antibiotics for Transfected Cell","Microbiology","Ceftazidime(GR20263) is a third-generation cephalosporin that has activity against Gram-negative bacilli, including Pseudomonas aeruginosa.",546.58,"72558-82-8",{"v":4,"d":"4.00"},7.32,{"v":100,"d":"100.00"},182.96,"http://selleckchem.com/products/ceftazidime.html","C22H22N6O7S2","inner salt","GR20263","CC(C)(O\\N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)C[N+]3=CC=CC=C3)C4=CSC(=N4)N)C(O)=O",-0.693,6,2,9]
["S3667","Imipenem","c11","L3800-49","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP7.5,JP17,印度药典","Preregistration","β-lactamase","Microbiology","Imipenem acts as an inhibitor of AmpC β-lactamase and is an antibiotic useful for the treatment of a number of bacterial infections.",317.36,"74431-23-5",{"v":1,"d":"1.00"},3.15,{"v":63,"d":"63.00"},198.51,"http://selleckchem.com/products/imipenem.html","C12H17N3O4S.H2O","hydrate","N/A","O.CC(O)C1C2CC(=C(N2C1=O)C(O)=O)SCCNC=N",-1.825,2,2,7]
["S3737","Cangrelor Tetrasodium","d11","L3800-49","in 10mM Water","DMF","N/A","Marketed","P2 Receptor","Neuronal Signaling","Cangrelor (AR-C69931MX) is a potent, competitive P2Y12 receptor inhibitor that is administered by intravenous infusion and rapidly achieves near complete inhibition of ADP-induced platelet aggregation.",864.29,"163706-36-3",{"v":2,"d":"2.00"},2.31,{"v":100,"d":"100.00"},{"v":115.7,"d":"115.70"},"http://selleckchem.com/products/cangrelor-tetrasodium.html","21Cl2F3N5O12P3S2.4Na","tetrasodium salt","AR-C69931MX","CSCCNC1=NC(=NC2=C1N=C[N]2C3OC(CO[P](=O)(O[Na])O[P](=O)(O[Na])C(Cl)(Cl)[P](=O)(O[Na])O[Na])C(O)C3O)SCCC(F)(F)F",2.787,10,3,20]
["S3753","L-Leucine","g11","L3800-49","in 10mM Water","NDC,DMF","KP Ⅹ,JP17,BP2015","Phase 2","mTOR","PI3K/Akt/mTOR","Leucine ((S)-Leucine, Leu) is one of nine essential amino acids in humans which is important for protein synthesis and many metabolic functions. It contributes to regulation of blood-sugar levels; growth and repair of muscle and bone tissue; growth hormone production; and wound healing.  L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway.",131.17,"61-90-5","<1","N/A",{"v":5,"d":"5.00"},38.12,"http://selleckchem.com/products/l-leucine.html","C6H13NO2","free base","(S)-Leucine, Leu","CC(C)CC(N)C(O)=O",{"v":0,"d":"0.000"},0,0,0]
["S3861","Sodium Demethylcantharidate","b2","L3800-50","in 10mM Water","CFDA","N/A","N/A","PP2A","PI3K/Akt/mTOR","Demethylcantharidin (norcantharidin) is a synthetic analogue of cantharidin and has potent antitumor activity.",208.14,"13114-29-9","<1","N/A",{"v":41,"d":"41.00"},196.98,"http://selleckchem.com/products/sodium-demethylcantharidate.html","C8H9O5.Na","free base","Sodium norcantharidin","OC(=O)C1C2CCC(O2)C1C(=O)O[Na]",{"v":0,"d":"0.000"},0,0,0]
["S4008","Pemirolast potassium","f2","L3800-50","in 10mM Water","FDA,CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17","Marketed","Histamine Receptor","Neuronal Signaling","Pemirolast potassium (BMY26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.",{"v":266.3,"d":"266.30"},"100299-08-9","<1","N/A",{"v":53,"d":"53.00"},199.02,"http://selleckchem.com/products/pemirolast-bmy-26517-potassium.html","C10H7N6O.K","Potassium","BMY26517","[K+].CC1=CC=CN2C(=O)C(=CN=C12)C3=NN=N[N-]3",-1.246,5,0,1]
["S4028","Dexamethasone Sodium Phosphate","a3","L3800-50","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.1,Ph.Int_6th,BP2017,IP2010","Registered","Autophagy,Complement System,COVID-19,COX,IL Receptor","Immunology & Inflammation","Dexamethasone (Dexamethasone 21-phosphate disodium salt) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator  that has anti-inflammatory and immunosuppressant effects.",{"v":516.4,"d":"516.40"},"55203-24-2","<1","N/A",{"v":103,"d":"103.00"},199.46,"http://selleckchem.com/products/dexamethasone-sodium-phosphate.html","C22H30FO8P.2Na","Disodium salt","Dexamethasone 21-phosphate disodium salt","[Na+].[Na+].CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO[P]([O-])([O-])=O",-0.541,3,1,4]
["S4093","Bismuth Subcitrate Potassium","e3","L3800-50","in 10mM Water","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","Phase 3","Antibiotics,Bacterial","Microbiology","Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.",782.67,"880149-29-1","<1","N/A",{"v":100,"d":"100.00"},127.77,"http://selleckchem.com/products/bismuth-subcitrate-potassium.html","C12H8BiK5O14","Potassium salt","N/A","[K+].[K+].[K+].[K+].[K+].[BiH6+3].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O",-11.482,0,0,10]
["S4117","Histamine Phosphate","h3","L3800-50","in 10mM Water","FDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP7.5,BP2017,IP2010","Marketed","Histamine Receptor","Neuronal Signaling","Histamine(Histamine diphosphate) acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors.",307.14,"51-74-1","<1","N/A",{"v":42,"d":"42.00"},136.75,"http://selleckchem.com/products/histamine-phosphate.html","C5H9N.2H3O4P","Phosphate","Histamine diphosphate","NCCC1=C[NH]C=N1.O[P](O)(O)=O.O[P](O)(O)=O",-1.651,1,2,2]
["S4130","Mildronate","c4","L3800-50","in 10mM Water","N/A","N/A","Marketed","Hydroxylase","Metabolism","Mildronate (Meldonium, MET-88, Quaterin) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.",147.19,"76144-81-5","<1","N/A",{"v":29,"d":"29.00"},197.02,"http://selleckchem.com/products/mildronate.html","C6H14N2O2","free base","Meldonium, MET-88, Quaterin","C[N+](C)(C)NCCC(O)=O",-1.797,1,1,4]
["S4137","Eprazinone 2HCl","d4","L3800-50","in 10mM Water","CFDA,PMDA","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Eprazinone (NSC 317935) is a mucolytic.",453.44,"10402-53-6",{"v":1,"d":"1.00"},2.21,{"v":18,"d":"18.00"},{"v":39.7,"d":"39.70"},"http://selleckchem.com/products/eprazinone-2hcl.html","C24H32N2O2.2HCl","HCl","NSC 317935","Cl.Cl.CCOC(CN1CCN(CC1)CC(C)C(=O)C2=CC=CC=C2)C3=CC=CC=C3",4.838,2,0,9]
["S4157","Chloroquine diphosphate","g4","L3800-50","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,Ph.Int_6th,BP2017,IP2010","N/A","Anti-infection,ATM/ATR,Autophagy,COVID-19,TLR","PI3K/Akt/mTOR","Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. Chloroquine is also an inhibitor of toll-like receptors (TLRs).",515.86,"50-63-5","<1","N/A",{"v":100,"d":"100.00"},193.85,"http://selleckchem.com/products/chloroquine-phosphate.html","C18H26ClN3.2H3O4P","diphosphate","N/A","CCN(CC)CCCC(C)NC1=CC=NC2=C1C=CC(=C2)Cl.O[P](O)(O)=O.O[P](O)(O)=O",3.408,1,1,8]
["S4183","Paromomycin Sulfate","c5","L3800-50","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,Ph.Int_6th","Marketed","Antibiotics,Antibiotics for Mammalian Cell Culture,Antibiotics for Plant Cell Culture,Selection Antibiotics for Transfected Cell","Microbiology","Paromomycin Sulfate(Aminosidine sulfate) is an aminoglycoside antibiotics inhibiting protein synthesis in non-resistant cells by binding to 16S ribosomal RNA.",713.71,"1263-89-4","<1","N/A",{"v":100,"d":"100.00"},140.11,"http://selleckchem.com/products/paromomycin-sulfate.html","C23H45N5O14.xH2SO4","Sulfate","Aminosidine sulfate","NCC1OC(OC2C(O)C(OC2CO)OC3C(O)C(N)CC(N)C3OC4OC(CO)C(O)C(O)C4N)C(N)C(O)C1O.O[S](O)(=O)=O",-9.277,6,13,9]
["S4236","Proflavine Hemisulfate","f5","L3800-50","in 10mM Water","NDC","Martindale:The Extra Pharmacopoeia","Phase 2","Anti-infection,DNA/RNA Synthesis","Microbiology","Proflavine Hemisulfate is a topical antiseptic by interchelating DNA, thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands.",258.25,"1811-28-5","<1","N/A",{"v":22,"d":"22.00"},85.19,"http://selleckchem.com/products/proflavine-hemisulfate.html","C13H11N3.1/2H2SO4","Sulfate","N/A","NC1=CC=C2C=C3C=CC(=CC3=NC2=C1)N.NC4=CC=C5C=C6C=CC(=CC6=NC5=C4)N.O[S](O)(=O)=O",3.113,2,4,0]
["S4271","Isepamicin Sulphate","a6","L3800-50","in 10mM Water","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,JP17","Marketed","Antibiotics,Bacterial","Microbiology","Isepamicin Sulphate (Isepamicine, Isepamycin, sch21420) is an aminoglycoside antibiotic, which inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit.",667.68,"67814-76-0","<1","N/A",{"v":100,"d":"100.00"},149.77,"http://selleckchem.com/products/isepamicin-sulphate.html","C22H45N5O16S","free base","Isepamicine (Isepamycin, sch21420) Sulphate","CNC1C(O)C(OCC1(C)O)OC2C(O)C(OC3OC(CN)C(O)C(O)C3O)C(N)CC2NC(=O)C(O)CN.O[S](O)(=O)=O",-7.948,5,11,9]
["S4314","Ceftazidime Pentahydrate","e6","L3800-50","in 10mM Water","DMF,HMA","Martindale:The Extra Pharmacopoeia,EP9.3,BP2017","Marketed","Others","Others","Ceftazidime is a β-lactam antibacterial agent which has demonstrated a broad spectrum of activity against Gram-positive and Gram-negative aerobic bacteria.",636.65,"78439-06-2",{"v":4,"d":"4.00"},6.28,{"v":100,"d":"100.00"},157.07,"http://www.selleckchem.com/products/ceftazidime-pentahydrate.html","C22H32N6O12S2","Pentahydrate","O.O.O.O.O.[H][C@]12SCC(C[N+]3=CC=CC=C3)=C(N1C(=O)[C@H]2NC(=O)C(=N\\OC(C)(C)C(O)=O)\\C1=CSC(N)=N1)C([O-])=O |r, c:8, 10, 12, 36, t:6, 32|","O.O.O.O.O.CC(C)(O/N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C([O-])=O)C[N+]3=CC=CC=C3)C4=CSC(=N4)N)C(O)=O",{"v":6,"d":"6.000"},2,9]
["S4392","Potassium Canrenoate","h6","L3800-50","in 10mM Water","PMDA","Martindale:The Extra Pharmacopoeia,JP17","Phase 4","Others","Others","N/A",396.56,"2181-04-6","N/A","N/A",{"v":40,"d":"40.00"},100.87,"http://selleckchem.com/products/potassium-canrenoate.html","C22H29KO4","Potassium salt","Canrenoic Acid Potassium Salt","[K+].CC12CCC(=O)C=C1C=CC3C2CCC4(C)C3CCC4(O)CCC([O-])=O","N/A","N/A","N/A","N/A"]
["S4430","Hydroxychloroquine Sulfate (NSC 4375)","a7","L3800-50","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.3,KP Ⅹ,BP2017","Phase 3","Anti-infection,Autophagy,COVID-19,TLR","Autophagy","Hydroxychloroquine Sulfate (NSC 4375, HCQ) is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.",433.95,"747-36-4","<1","N/A",{"v":67,"d":"67.00"},{"v":154.4,"d":"154.40"},"http://selleckchem.com/products/hydroxychloroquine-sulfate.html","C18H28ClN3O5S","Sulfate","HCQ","CCN(CCO)CCCC(C)NC1=CC=NC2=CC(=CC=C12)Cl.O[S](O)(=O)=O",{"v":2.85,"d":"2.850"},1,2,9]
["S4540","Sisomicin sulfate","c7","L3800-50","in 10mM Water","CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,JP15","Phase 4","Antibiotics","Microbiology","Sisomicin sulfate is an aminoglycoside antibiotic, isolated from the fermentation broth of a new species of the genus Micromonospora.",1385.45,"53179-09-2","<1","N/A",{"v":100,"d":"100.00"},72.18,"http://selleckchem.com/products/sisomicin-sulfate.html","2C19H37N5O7.5H2SO4","Sulfate","N/A","CNC1C(O)C(OCC1(C)O)OC2C(N)CC(N)C(OC3OC(=CCC3N)CN)C2O.CNC4C(O)C(OCC4(C)O)OC5C(N)CC(N)C(OC6OC(=CCC6N)CN)C5O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O",-12.405,8,14,12]
["S4582","Eflornithine (MDL-71782) hydrochloride hydrate","f7","L3800-50","in 10mM Water","FDA,DMF,EMA,NDC","Martindale:The Extra Pharmacopoeia","Phase 2","Decarboxylase","Metabolism","Eflornithine (Difluoromethylornithine, DFMO, MDL-71782, RMI-71782, α-difluoromethylornithine) hydrochloride hydrate inhibits polyamine biosynthesis by the selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis. Its biological half-life is 8 hours.",236.64,"96020-91-6","<1","N/A",{"v":47,"d":"47.00"},198.61,"http://selleckchem.com/products/eflornithine-hydrochloride-hydrate.html","C6H12F2N2O2.HCl.H2O","hydrochloride hydrate","Difluoromethylornithine hydrochloride hydrate, DFMO hydrochloride hydrate, RMI-71782 hydrochloride hydrate, α-difluoromethylornithine hydrochloride hydrate","O.Cl.NCCCC(N)(C(F)F)C(O)=O",-3.046,1,2,5]
["S4671","Cefradine","b8","L3800-50","in 10mM Water","CFDA","Martindale:The Extra Pharmacopoeia,CP2005,KP Ⅹ,EP9.2,BP2017","N/A","Antibiotics","Microbiology","Cefradine (Cephradine, Sefril, Anspor, Velosef) is a semi-synthetic cephalosporin antibiotic.",{"v":349.4,"d":"349.40"},"38821-53-3","<1","N/A",{"v":10,"d":"10.00"},28.62,"http://selleckchem.com/products/cefradine.html","C16H19N3O4S","free base","Cephradine, Sefril, Anspor, Cephradin, Velosef","CC1=C(N2C(SC1)C(NC(=O)C(N)C3=CCC=CC3)C2=O)C(O)=O",-2.277,3,2,4]
["S4703","Choline bitartrate","e8","L3800-50","in 10mM Water","CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","N/A","AChR","Neuronal Signaling","Choline bitartrate (2-hydroxyethyl(trimethyl)azanium, 2,3,4-trihydroxy-4-oxobutanoate) is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acetylcholine, a chemical that facilitates communication between the nerves and muscles.",253.25,"87-67-2","<1","N/A",{"v":50,"d":"50.00"},197.43,"http://selleckchem.com/products/choline-bitartrate.html","C5H14NO.C4H5O6","tartrate","2-hydroxyethyl(trimethyl)azanium;2,3,4-trihydroxy-4-oxobutanoate","C[N+](C)(C)CCO.OC(C(O)C([O-])=O)C(O)=O",-4.712,1,3,5]
["S4740","Sodium ferulate","h8","L3800-50","in 10mM Water","CFDA","CP2005","N/A","5-HT Receptor","Neuronal Signaling","Sodium ferulate (SF, Ferulic acid sodium salt), the sodium salt of ferulic acid, is a drug used in traditional Chinese medicine for treatment of cardiovascular and cerebrovascular diseases and to prevent thrombosis.",216.17,"24276-84-4",{"v":2,"d":"2.00"},9.25,{"v":43,"d":"43.00"},198.92,"http://selleckchem.com/products/ferulic-acid-sodium.html","C10H9O4.Na","Sodium salt","Ferulic acid sodium salt","[Na+].COC1=CC(=CC=C1O)\\C=C\\C([O-])=O",0.195,1,1,3]
["S4811","VitaMin U","d9","L3800-50","in 10mM Water","DMF,CFDA","N/A","N/A","Vitamin","Metabolism","Vitamin U (Methylmethioninesulfonium Chloride, Cabagin-U, Smethylmethionine) is a vitamin found in green vegetables. It is used in the treatment of peptic ulcers, colitis, and gastritis and has an effect on secretory, acid-forming, and enzymatic functions of the intestinal tract.",{"v":199.7,"d":"199.70"},"3493-12-7","<1","N/A",{"v":39,"d":"39.00"},195.29,"http://selleckchem.com/products/vitamin-u.html","C6H14NO2.Cl","chloride","Methylmethioninesulfonium Chloride, Cabagin-U, Smethylmethionine","[Cl-].C[S+](C)CCC(N)C(O)=O",{"v":0,"d":"0.000"},0,0,0]
["S4828","Sodium carbonate","g9","L3800-50","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,BP2016,USP39-NF34,JP16,IP2010","N/A","Others","Others","Sodium Carbonate (Disodium carbonate, Soda Ash, Carbonic acid disodium salt) is the disodium salt of carbonic acid with alkalinizing property.",105.99,"497-19-8","<1","N/A",{"v":21,"d":"21.00"},198.13,"http://selleckchem.com/products/sodium-carbonate.html","Na2CO3","disodium salt of carbonic acid","Disodium carbonate, Soda Ash, Carbonic acid disodium salt","[Na]OC(=O)O[Na]",0.394,3,0,2]
["S4950","L(+)-Asparagine monohydrate","h9","L3800-50","in 10mM Water","DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,EP9.2,BP2017","N/A","Others","Others","L-asparagine is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue, being used for a variety of pharmaceutical applications.",150.13,"5794-13-8","<1","N/A",{"v":30,"d":"30.00"},199.83,"http://www.selleckchem.com/products/l-asparagine-monohydrate.html","C4H8N2O3.H2O","monohydrate","N/A","O.NC(CC(N)=O)C(O)=O",-4.615,2,2,3]
["S4993","Timonacic","c10","L3800-50","in 10mM Water","N/A","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Timonacic (Thiazolidine-4-carboxylic acid, Detoxepa, Hepalidine, 1,3-Thiazolidine-4-carboxylic acid) is a cyclic sulfur amino acid derivative with potential antineoplastic and antioxidant activities.",133.17,"444-27-9",{"v":1,"d":"1.00"},7.51,{"v":27,"d":"27.00"},202.75,"http://www.selleckchem.com/products/timonacic.html","C4H7NO2S","Free Base","Thiazolidine-4-carboxylic acid, Detoxepa, Hepalidine, 1,3-Thiazolidine-4-carboxylic acid","OC(=O)C1CSCN1",-2.889,1,1,1]
["S5097","Methotrexate disodium","f10","L3800-50","in 10mM Water","DMF,HMA","Martindale:The Extra Pharmacopoeia","Marketed","Dehydrogenase,DHFR","Metabolism","Methotrexate sodium, an inhibitor of tetrahydrofolate dehydrogenase, is an antineoplastic antimetabolite with immunosuppressant properties.",{"v":498.4,"d":"498.40"},"7413-34-5","<1","N/A",{"v":99,"d":"99.00"},198.64,"http://selleckchem.com/products/methotrexate-disodium.html","C20H20N8O5.2Na","disodium salt","N/A","[Na+].[Na+].CN(CC1=NC2=C(N)N=C(N)N=C2N=C1)C3=CC=C(C=C3)C(=O)NC(CCC([O-])=O)C([O-])=O",-2.834,5,3,9]
["S5136","Calcium folinate","b11","L3800-50","in 10mM Water","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,EP9.7,KP Ⅹ,Ph.Int_6th,BP2017,IP2010","Phase 3","DHFR","Metabolism","Calcium folinate (Leucovorin calcium, Folinic acid calcium salt, Wellcovorin) is a metabolically active, reduced form of folic acid that is rapidly absorbed and extensively metabolized in the liver to other folic acid derivatives.",{"v":511.5,"d":"511.50"},"1492-18-8","<1","N/A",{"v":100,"d":"100.00"},{"v":195.5,"d":"195.50"},"http://selleckchem.com/products/calcium-folinate.html","C20H21N7O7.Ca","calcium salt","Leucovorin calcium, Folinic acid calcium salt, Wellcovorin","[Ca++].NC1=NC(=C2N(C=O)C(CNC3=CC=C(C=C3)C(=O)NC(CCC([O-])=O)C([O-])=O)CNC2=N1)O",{"v":0,"d":"0.000"},0,0,0]
["S5252","Ozagrel sodium","e11","L3800-50","in 10mM Water","CFDA,PMDA","JP17","Marketed","P450 (e.g. CYP17),Prostaglandin Receptor","Metabolism","Ozagrel sodium (KCT-0809, Cataclot, Xanbo) is a thromboxane A2 synthase (CYP5) inhibitor with neuroprotective properties.",250.23,"189224-26-8",{"v":1,"d":"1.00"},{"v":4,"d":"4.00"},{"v":50,"d":"50.00"},199.82,"http://selleckchem.com/products/ozagrel-sodium.html","C13H11N2O2.Na","sodium","KCT-0809, Cataclot, Xanbo","[Na+].[O-]C(=O)\\C=C\\C1=CC=C(C[N]2C=CN=C2)C=C1",{"v":0.13,"d":"0.130"},1,0,4]
["S5362","Citicoline","h11","L3800-50","in 10mM Water","DMF, CFDA, PMDA","USP43-NF38, JP17","N/A","Others","Others","Citicoline (CDP-choline, cytidine 5'-diphosphocholine) is a naturally occurring compound that acts as nutrient with a broad spectrum of benefits for conditions associated with symptoms of neurological dysfunction. As an endogenous compound, it is also an essential intermediate in the synthesis of cell membrane phospholipids and its formation is the rate-limiting step in phosphatidylcholine synthesis.",488.32,"987-78-0","<1","N/A",{"v":97,"d":"97.00"},198.64,"https://www.selleckchem.com/products/citicoline.html","C14H26N4O11P2","inner salt","CDP-choline, cytidine 5'-diphosphocholine","C[N+](C)(C)CCO[P]([O-])(=O)O[P](O)(=O)OCC1OC(C(O)C1O)N2C=CC(=NC2=O)N",-5.406,6,3,10]
["S5496","Guanethidine Monosulfate","d2","L3800-51","in 10mM Water","FDA,DMF","USP42-NF37,EP9.1,BP2017","N/A","Adrenergic Receptor","Neuronal Signaling","Guanethidine monosulfate is an antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves.",296.39,"645-43-2","<1","N/A",{"v":59,"d":"59.00"},199.06,"http://selleckchem.com/products/guanethidine-monosulfate.html","C10H22N4.H2SO4","sulfate","N/A","NC(=N)NCCN1CCCCCCC1.O[S](O)(=O)=O",0.579,0,2,4]
["S5533","Tobramycin sulfate","g2","L3800-51","in 10mM Water","FDA,DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ","Marketed","Antibiotics,Bacterial","Microbiology","Tobramycin sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity.",1425.42,"49842-07-1","<1","N/A",{"v":100,"d":"100.00"},70.15,"https://www.selleckchem.com/products/tobramycin-sulfate.html","C36H84N10O38S5","free base","N/A","NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)CC1O.NCC4OC(OC5C(N)CC(N)C(OC6OC(CO)C(O)C(N)C6O)C5O)C(N)CC4O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O",-16.755,8,20,12]
["S5545","DL-Serine","h2","L3800-51","in 10mM Water","N/A","Martindale:The Extra Pharmacopoeia","N/A","PKM","Metabolism","Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2.",105.09,"302-84-1","<1","N/A",{"v":8,"d":"8.00"},76.13,"http://selleckchem.com/products/dl-serine.html","C3H7NO3","salt","N/A","NC(CO)C(O)=O",-4.049,1,2,2]
["S5588","Creatine","c3","L3800-51","in 10mM Water","DMF,CFDA","Martindale:The Extra Pharmacopoeia","N/A","IFN,JAK","JAK/STAT","Creatine (Methylguanidoacetic acid) is a nitrogenous organic acid that occurs naturally in vertebrates. It facilitates the recycling of adenosine triphosphate (ATP) primarily in muscle and brain tissue.Creatine can inhibits the JAK-STAT1 signal transmission by inhibiting the interaction of IFN-γ receptors with JAK2 in an ATP-independent manner, thereby inhibiting downstream pro-inflammatory gene expression.",131.13,"57-00-1","<1","N/A",{"v":26,"d":"26.00"},198.28,"http://selleckchem.com/products/creatine.html","C4H9N3O2","free base","Methylguanidoacetic acid","CN(CC(O)=O)C(N)=N",-1.095,1,1,3]
["S5629","L-Proline","f3","L3800-51","in 10mM Water","DMF,NDC","JP17","N/A","Others","Others","L-Proline is one of non-essential amino acids and an essential component of collagen that is important for proper functioning of joints and tendons.",115.13,"147-85-3","<1","N/A",{"v":23,"d":"23.00"},199.77,"http://selleckchem.com/products/l-proline.html","C5H9NO2","free base","N/A","OC(=O)C1CCCN1",-2.843,1,1,1]
["S5633","L-methionine","b4","L3800-51","in 10mM Water","DMF,CFDA,NDC","EP9.2,JP17,Ph.Int_5th,BP2013","N/A","Others","Others","L-Methionine is an essential sulfur-containing, free-form amino acid, acts as an antioxidant promoter, and contributes to the synthesis of S-adenosyl-L-methionine (SAMe).",149.21,"63-68-3","<1","N/A",{"v":29,"d":"29.00"},194.36,"http://selleckchem.com/products/l-methionine.html","C5H11NO2S","free base","N/A","CSCCC(N)C(O)=O",-2.834,1,1,4]
["S5660","Clodronate disodium tetrahydrate","e4","L3800-51","in 10mM Water","DMF","EP9.1,BP2015","Marketed","Others","Others","Clodronate disodium tetrahydrate (clodronic acid) is a diphosphonate which affects calcium metabolism. It inhibits bone resorption and soft tissue calcification.",360.92,"88416-50-6","<1","N/A",{"v":72,"d":"72.00"},199.49,"https://www.selleckchem.com/products/clodronate-disodium-tetrahydrate.html","CH10Cl2Na2O10P2","free base","clodronic acid disodium tetrahydrate","O.O.O.O.[Na+].[Na+].O[P]([O-])(=O)C(Cl)(Cl)[P](O)([O-])=O",-2.534,0,0,2]
["S5706","Edetate Trisodium","g4","L3800-51","in 10mM Water","FDA,DMF,CFDA,NDC,HMA","N/A","N/A","Others","Others","Edetate Trisodium (EDTA trisodium salt, ethylenediaminetetraacetic acid) is the organic sodium salt of ethylenediaminetetraacetic acid (EDTA). EDTA is a chelating agent capable of removing a heavy metal, such as lead or mercury, from the blood.",358.19,"150-38-9","<1","N/A",{"v":36,"d":"36.00"},100.51,"https://www.selleckchem.com/products/edetate-trisodium.html","C10H13N2Na3O8","free base","EDTA Trisodium, ethylenediaminetetraacetic acid Trisodium","[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O",-9.072,1,0,11]
["S5721","Edetate calcium disodium","h4","L3800-51","in 10mM Water","FDA,DMF,NDC","USP38-NF33","N/A","Others","Others","Edetate (EDTA) calcium disodium is a chelating agent that is primarily used for the management of severe lead poisoning.",374.27,"62-33-9","<1","N/A",{"v":75,"d":"75.00"},200.39,"http://www.selleckchem.com/products/edetate-calcium-disodium.html","C10H12CaN2Na2O8","disodium salt","EDTA calcium disodium","[Na+].[Na+].[Ca++].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O",-7.512,0,0,11]
["S5746","pentetate calcium trisodium hydrate","a5","L3800-51","in 10mM Water","FDA,NDC,PMDA","EP9.3;BP2019","N/A","Others","Others","pentetate calcium trisodium hydrate (Ca-DTPA) is an iron chelating agent.",497.35,"207226-35-5","<1","N/A",{"v":100,"d":"100.00"},201.07,"http://www.selleckchem.com/products/pentetate-calcium-trisodium-hydrate.html","C14H18CaN3Na3O10.xH2O","trisodium hydrate","Ca-DTPA","[Na+].[Na+].[Na+].[Ca++].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O",-8.631,0,0,16]
["S5801","Ala-Gln","b5","L3800-51","in 10mM Water","N/A","N/A","Phase 2","Others","Others","Ala-Gln (l-alanyl-l-glutamine), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals with better solubility and stability than glutamine (Gln).",217.22,"39537-23-0","<1","N/A",{"v":43,"d":"43.00"},197.96,"http://www.selleckchem.com/products/ala-gln.html","C8H15N3O4","Free Base","l-alanyl-l-glutamine","CC(N)C(=O)NC(CCC(N)=O)C(O)=O",-4.543,3,3,6]
["S5820","L-Hydroxyproline","c5","L3800-51","in 10mM Water","NDC","N/A","N/A","Others","Others","L-Hydroxyproline (trans-4-Hydroxy-L-proline) is a collagen-specific amino acid. It is used as a diagnostic marker of bone turnover and liver fibrosis.",131.13,"51-35-4",{"v":1,"d":"1.00"},7.63,{"v":26,"d":"26.00"},198.28,"http://www.selleckchem.com/products/l-hydroxyproline.html","C5H9NO3","Free Base","trans-4-Hydroxy-L-proline","OC1CNC(C1)C(O)=O",-3.934,1,2,1]
["S5866","Gastrodenol","d5","L3800-51","in 10mM Water","marketed in Spain","N/A","N/A","Others","Others","Gastrodenol (Bismuth tripotassium dicitrate) is used to treat certain conditions caused by too much acid being produced in the stomach, such as stomach ulcers and ulcers of the upper part of the intestine (duodenal ulcers).",704.47,"57644-54-9",{"v":1,"d":"1.00"},1.42,{"v":100,"d":"100.00"},141.95,"https://www.selleckchem.com/products/gastrodenol.html","C12H10BiK3O14","Free Base","Bismuth tripotassium dicitrate","[K+].[K+].[K+].[BiH6+3].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O",-11.482,0,0,10]
["S5867","Bendazac L-lysine","e5","L3800-51","in 10mM Water","CFDA","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Bendazac L-lysine has a protective effect against lens protein denaturation both in vitro and in vivo. It is also a nonsteroidal anti-inflammatory drug (NSAID) used for joint and muscular pain.",428.48,"81919-14-4",{"v":3,"d":"3.00"},{"v":7,"d":"7.00"},{"v":86,"d":"86.00"},200.71,"https://www.selleckchem.com/products/bendazac-l-lysine.html","C22H28N4O5","Free Base","N/A","NCCCCC(N)C(O)=O.OC(=O)COC1=N[N](CC2=CC=CC=C2)C3=C1C=CC=C3",-2.452,4,2,10]
["S6023","Creatine monohydrate","f5","L3800-51","in 10mM Water","CFDA,DMF","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Creatine (Methylguanidoacetic acid) is a key player in the phosphagen energy system, the primary source of ATP during short-term, high intensity activities.",149.15,"6020-87-7","N/A","N/A",5.96,39.94,"http://www.selleck.cn/products/creatine-monohydrate.html","C4H11N3O3","monohydrate","Methylguanidoacetic acid monohydrate","O.CN(CC(O)=O)C(N)=N",-1.302,1,1,3]
["S6102","Thiamine pyrophosphate hydrochloride","g5","L3800-51","in 10mM Water","CFDA, NDC","N/A","N/A","Vitamin","Metabolism","Thiamine pyrophosphate hydrochloride (cocarboxylase) is a thiamine (vitamin B1) derivative which is produced by the enzyme thiamine diphosphokinase. It is a coenzyme of many enzymes, most of which occur in prokaryotes and is involved in the regulation of basic metabolism.",460.77,"154-87-0","N/A","N/A",{"v":92,"d":"92.00"},199.67,"http://www.selleck.cn/products/thiamine-pyrophosphate-hydrochloride.html","C12H19ClN4O7P2S","hydrochloride","cocarboxylase hydrochloride","[Cl-].CC1=NC=C(C[N+]2=CSC(=C2C)CCO[P](O)(=O)O[P](O)(O)=O)C(=N1)N",-1.984,4,1,8]
["S6129","Aminomalonic acid","h5","L3800-51","in 10mM Water","N/A","N/A","Phase 1","Others","Others","Aminomalonic acid (Aminomalonate, Aminopropanedioic acid) is an amino dicarboxylic acid. It has a role as a human metabolite and a Daphnia magna metabolite.",119.08,"1068-84-4","N/A","N/A",{"v":11,"d":"11.00"},92.37,"http://www.selleck.cn/products/aminomalonic-acid.html","C3H5NO4","free base","Aminomalonate, Aminopropanedioic acid","NC(C(O)=O)C(O)=O",-3.815,2,1,2]
["S6176","Scyllo-Inositol","a6","L3800-51","in 10mM Water","N/A","N/A","Phase 2/3","Others","Others","Scyllo-Inositol (Scyllitol, Cocositol, Quercinitol, AZD 103, Scyllo-Cyclohexanehexol) is a naturally occurring plant sugar alcohol found most abundantly in the coconut palm.",180.16,"488-59-5","N/A","N/A",9.03,50.11,"http://www.selleck.cn/products/scyllo-inositol.html","C6H12O6","free base","Scyllitol, Cocositol, Quercinitol, AZD 103, Scyllo-Cyclohexanehexol","OC1C(O)C(O)C(O)C(O)C1O",-3.065,0,6,0]
["S6201","Malachite green","b6","L3800-51","in 10mM Water","N/A","EP9.2;BP2017;IP2010","N/A","Others","Others","Malachite green (Aniline green, Basic green 4, Diamond green B, Victoria green B) is a synthetic dyestuff and antimicrobial with potential carcinogenicity.",{"v":927,"d":"927.00"},"2437-29-8","N/A","N/A",{"v":185.4,"d":"185.40"},{"v":200,"d":"200.00"},"http://www.selleck.cn/products/malachite-green.html","C52H54N4O12","free base","Aniline green, Basic green 4, Diamond green B, Victoria green B","CN(C)C1=CC=C(C=C1)C(C2=CC=CC=C2)=C3C=CC(C=C3)=[N+](C)C.CN(C)C4=CC=C(C=C4)C(C5=CC=CC=C5)=C6C=CC(C=C6)=[N+](C)C.OC(=O)C(O)=O.OC(=O)C([O-])=O.OC(=O)C([O-])=O",5.289,4,0,9]
["S6224","(R)-Serine","c6","L3800-51","in 10mM Water","CFDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,Ph.Int_6th,JP17","N/A","NMDAR","Neuronal Signaling","(R)-Serine is the R-enantiomer of serine, which is used in the biosynthesis of proteins. (R)-Serine acts as obligatory coagonist at the glycine site associated with the N-methyl-D-aspartate subtype of glutamate receptors (NMDAR) and has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration.",105.09,"312-84-5","N/A","N/A",21.02,{"v":200,"d":"200.00"},"http://www.selleck.cn/products/r-serine.html","C3H7NO3","free base","N/A","NC(CO)C(O)=O",-4.049,1,2,2]
["S6266","(S)-Glutamic acid","d6","L3800-51","in 10mM Water","CFDA,DMF,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,JP17,BP2017,IP2010","N/A","GluR","Neuronal Signaling","(S)-Glutamic acid (L-Glutamic acid) is an endogenous, non-selective glutamate receptor agonist.",147.13,"56-86-0","N/A","N/A",{"v":4,"d":"4.00"},27.19,"http://www.selleck.cn/products/s-glutamic-acid.html","C5H9NO4","free base","L-Glutamic acid","NC(CCC(O)=O)C(O)=O",-3.459,2,1,4]
["S6315","Sodium phytate hydrate","e6","L3800-51","in 10mM Water","CFDA","N/A","N/A","Others","Others","Sodium phytate hydrate (Phytic acid, Dodecasodium phytate, Myo-inositol hexakis, Inositol hexakisphosphate) functions as a storage depot and precursor for other inositol phosphates and pyrophosphates. It can be used clinically as a hypocalcemic agent and a complexing agent for removal of traces of heavy metal ions.",660.04,"14306-25-3","N/A","N/A",62.22,94.27,"http://www.selleck.cn/products/sodium-phytate-hydrate.html","C6H18O24P6.xNa.yH2O","hydrate","Phytic acid sodium hydrate, Dodecasodium phytate, Myo-inositol hexakis, Inositol hexakisphosphate","O[P](O)(=O)OC1C(O[P](O)(O)=O)C(O[P](O)(O)=O)C(O[P](O)(O)=O)C(O[P](O)(O)=O)C1O[P](O)(O)=O",-2.026,6,0,12]
["S6445","Chlorophyllin (sodium copper salt)","f6","L3800-51","in 10mM Water","CFDA","Martindale the Extra Pharmacopoei,USP42-NF37","N/A","Others","Others","Chlorophyllin, the sodium and copper salt of chlorophyll, is an antioxidant and antimutagenic agent.",724.15,"11006-34-1","<1","N/A",{"v":13,"d":"13.00"},17.95,"http://www.selleck.cn/products/chlorophyllin.html","C34H31CuN4Na3O6","sodium copper salt","N/A","[Na+].[Na+].[Na+].[Cu++]|1|2|3|[N-]4C5=C(C)C(=C4C=C6N|1=C(C=C7[N-]|2C(=C(CC([O-])=O)C8=N|3C(=C5)C(C)C8CCC([O-])=O)C(=C7C)C([O-])=O)C(=C6C)CC)C=C",-1.452,0,0,8]
["S6460","Sugammadex (sodium)","g6","L3800-51","in 10mM Water","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale the Extra Pharmacopoei","Marketed","Others","Others","Sugammadex (ORG-25969) is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery in adults.",2178.01,"343306-79-6","<1","N/A",{"v":100,"d":"100.00"},45.91,"http://www.selleck.cn/products/sugammadex.html","C72H104Na8O48S8","sodium","ORG-25969","[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].OC1C(O)C2OC3OC(CSCCC([O-])=O)C(OC4OC(CSCCC([O-])=O)C(OC5OC(CSCCC([O-])=O)C(OC6OC(CSCCC([O-])=O)C(OC7OC(CSCCC([O-])=O)C(OC8OC(CSCCC([O-])=O)C(OC9OC(CSCCC([O-])=O)C(OC1OC2CSCCC([O-])=O)C(O)C9O)C(O)C8O)C(O)C7O)C(O)C6O)C(O)C5O)C(O)C4O)C(O)C3O",-18.704,16,16,40]
["S6488","Gadoxetate sodium","h6","L3800-51","in 10mM Water","FDA,CFDA,NDC,PMDA","Martindale the Extra Pharmacopoei","Marketed","Others","Others","Gadoxetate is a paramagnetic gadolinium-containing contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection.",725.71,"135326-22-6","N/A","N/A",{"v":100,"d":"100.00"},{"v":137.8,"d":"137.80"},"http://www.selleck.cn/products/gadoxetate-sodium.html","C23H28GdN3Na2O11","sodium","N/A","[Na+].[Na+].[Gd+3]|1|2|3|4|5|6|7|[O-]C(=O)CN|1(CCN|2(CC([O-]|3)=O)CC([O-]|4)=O)CC(CC8=CC=C(OCC)C=C8)N|5(CC([O-]|6)=O)CC([O-]|7)=O",{"v":-3.48,"d":"-3.480"},1,0,4]
["S6592","Diquafosol Tetrasodium","a7","L3800-51","in 10mM Water","N/A","N/A","Marketed","P2 Receptor","Neuronal Signaling","Diquafosol Tetrasodium (INS-365), a P2Y2 receptor agonist, is a pharmaceutical drug for the treatment of dry eye disease.",878.23,"211427-08-6","N/A","N/A",{"v":100,"d":"100.00"},113.87,"http://www.selleck.cn/products/diquafosol-tetrasodium.html","C18H22N4Na4O23P4","Tetrasodium","INS-365","[Na+].[Na+].[Na+].[Na+].OC1C(O)C(OC1CO[P]([O-])(=O)O[P]([O-])(=O)O[P]([O-])(=O)O[P]([O-])(=O)OCC2OC(C(O)C2O)N3C=CC(=O)NC3=O)N4C=CC(=O)NC4=O",-11.332,11,6,14]
["S7204","Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium","b7","L3800-51","in 10mM Water","N/A","N/A","Phase 3","Apoptosis related,Microtubule Associated","Cytoskeletal Signaling","Fosbretabulin (Combretastatin A4 Phosphate, CA4P, CA 4DP) Disodium is the water-soluble prodrug of Combretastatin A4 (CA4), which is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM in a cell-free assay. Fosbretabulin Disodium inhibits the polymerization of tubulin with IC50 of 2.4 μM, and also disrupts tumor vasculature. Fosbretabulin disodium induces mitotic arrest and apoptosis in endothelial cells. Phase 3.",440.29,"168555-66-6","<1","N/A",{"v":28,"d":"28.00"},63.59,"http://selleckchem.com/products/fosbretabulin-disodium-combretastatin-a-4-phosphate-disodium-ca4p-disodium.html","C18H19O8P.2Na","Disodium salt","CA 4DP","[Na+].[Na+].COC1=C(O[P]([O-])([O-])=O)C=C(\\C=C/C2=CC(=C(OC)C(=C2)OC)OC)C=C1",1.077,5,0,8]
["S7548","Rilmenidine Phosphate","c7","L3800-51","in 10mM Water","marketed in Hungary, Poland and the Czech Republic","Martindale:The Extra Pharmacopoeia","Marketed","Imidazoline Receptor","GPCR & G Protein","Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used for the treatment of hypertension.",278.24,"85409-38-7",{"v":1,"d":"1.00"},3.59,{"v":55,"d":"55.00"},197.67,"http://selleckchem.com/products/rilmenidine-phosphate.html","C10H19N2O5P","Phosphate","N/A","O[P](O)(O)=O.C1CN=C(NC(C2CC2)C3CC3)O1",1.296,2,1,4]
["S7785","Pemetrexed Disodium Hydrate","d7","L3800-51","in 10mM Water","DMF","Martindale:The Extra Pharmacopoeia,EP9.1,BP2017","Marketed","Apoptosis related,Autophagy,DHFR","Metabolism","Pemetrexed Disodium Hydrate (LY-231514) is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively. Pemetrexed Disodium Hydrate stimulates autophagy and apoptosis.",516.42,"357166-30-4","<1","N/A",{"v":100,"d":"100.00"},193.64,"http://selleckchem.com/products/pemetrexed-disodium-hydrate.html","C20H21N5O6.5/2H2O.2Na","Disodium Hydrate","LY-231514 Disodium Hydrate","NC1=NC(=O)C2=C([NH]C=C2CCC3=CC=C(C=C3)C(=O)NC(CCC(=O)O[Na])C(=O)O[Na])N1",{"v":2.06,"d":"2.060"},7,4,11]
["S8199","Ruxotemitide (LTX 315)","e7","L3800-51","in 10mM Water","N/A","N/A","Phase 2","Bcl-2","Apoptosis","Ruxotemitide (LTX 315, Oncopore) is the oncolytic peptide that kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization.",1439.79,"1345407-05-7","N/A","N/A",{"v":100,"d":"100.00"},69.45,"http://selleckchem.com/products/ltx-315.html","C78H106N18O9","free base","Oncopore","NCCCCC(N)C(=O)NC(CCCCN)C(=O)NC(CC1=C[NH]C2=C1C=CC=C2)C(=O)NC(CC3=C[NH]C4=C3C=CC=C4)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC5=C[NH]C6=C5C=CC=C6)C(=O)NC(C(C7=CC=CC=C7)C8=CC=CC=C8)C(=O)NC(CCCCN)C(N)=O",3.102,9,18,46]
["S8442","TAK-659","f7","L3800-51","in 10mM Water","N/A","N/A","Phase 2","FLT3,Syk","Angiogenesis","TAK-659 is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.",380.85,"1952251-28-3","<1","N/A",{"v":4,"d":"4.00"},{"v":10.5,"d":"10.50"},"http://selleckchem.com/products/tak-659.html","C17H21FN6.HCl","hydrochloride","N/A","Cl.C[N]1C=C(C=N1)C2=C3C(=O)NCC3=C(F)C(=N2)NC4CCCCC4N",1.774,3,3,3]
["S8501","Adaptavir (DAPTA)","g7","L3800-51","in 10mM Water","N/A","N/A","Phase 2","CCR","Immunology & Inflammation","Adaptavir (DAPTA, D-Ala-peptide T-amide, peptide T) is a water soluble potent, selective CCR5 antagonist which potently inhibits specific CD4-dependent binding of gp120 Bal (IC50 = 0.06 nM) and CM235 (IC50 = 0.32 nM) to CCR5.",856.88,"106362-34-9","N/A","N/A",{"v":100,"d":"100.00"},{"v":116.7,"d":"116.70"},"http://selleckchem.com/products/dapta.html","C35H56N10O15","free base","D-Ala-peptide T-amide, peptide T","CC(N)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NC(CC(N)=O)C(=O)NC(CC1=CC=C(O)C=C1)C(=O)NC(C(C)O)C(N)=O",-7.366,9,16,24]
["S9344","DL-Methionine","h7","L3800-51","in 10mM Water","DMF","Martindale:The Extra Pharmacopoeia,EP9.2,Ph.Int_6th,BP2013","N/A","Antiviral","Microbiology","DL-Methionine is an amino acid that has a role in the defence of oxidative stress.",149.21,"59-51-8","N/A",{"v":0,"d":"0.00"},{"v":6,"d":"6.00"},40.21,"https://www.selleckchem.com/products/dl-methionine.html","C5H11NO2S","free base","N/A","CSCCC(N)C(O)=O",-2.834,1,1,4]
["S9353","L-serine","a8","L3800-51","in 10mM Water","DMF","JP17,BP2015","N/A","Others","Others","L-serine, one of the so-called non-essential amino acids, plays a central role in cellular proliferation.",105.09,"56-45-1","N/A",{"v":0,"d":"0.00"},{"v":21,"d":"21.00"},199.82,"https://www.selleckchem.com/products/l-serine.html","C3H7NO3","free base","N/A","NC(CO)C(O)=O",-4.049,1,2,2]
["S9367","Adenosine disodium triphosphate hydrate","b8","L3800-51","in 10mM Water","CFDA","CP2005","N/A","Others","Others","Adenosine disodium triphosphate hydrate(ATP disodium) is the sodium salt form of adenosine triphosphate (ATP), a complex organic chemical that provides energy to drive many processes in living cells., ,",551.14,"34369-07-8","N/A",{"v":0,"d":"0.00"},{"v":100,"d":"100.00"},181.44,"https://www.selleckchem.com/products/adenosine-disodium-triphosphate.html","C10H14N5Na2O13P3.xH2O","disodium triphosphate hydrate","ATP disodium","O[C@H]1([C@H](N2C3C(N=C2)=C(N)N=CN=3)O[C@H](CO[P](O[P](O[P](=O)(O)O)(=O)O)(=O)O)[C@@H](O)1).[Na].O",-5.474,7,3,8]
["P1004","Bivalirudin Trifluoroacetate","c8","L3800-51","in 10mM Water","FDA,DMF,EMA,HMA,CFDA,NDC","N/A","Marketed","N/A","Angiogenesis","Bivalirudin Trifluoroacetate is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin.",2180.33,"128270-60-0","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://www.selleckchem.com/peptide/bivalirudin-trifluoroacetate.html","C98H138N24O33","Trifluoroacetate","D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH","CCC(C)C(NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CC(N)=O)NC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)C2CCCN2C(=O)C(CCCNC(N)=N)NC(=O)C3CCCN3C(=O)C(N)CC4=CC=CC=C4)C(=O)N5CCCC5C(=O)NC(CCC(O)=O)C(=O)NC(CCC(O)=O)C(=O)NC(CC6=CC=C(O)C=C6)C(=O)NC(CC(C)C)C(O)=O",{"v":0,"d":"0.000"},0,0,0]
["P1011","Eptifibatide Acetate","d8","L3800-51","in 10mM Water","DMF","Martindale:The Extra Pharmacopoeia","Marketed","5-alpha Reductase","Angiogenesis","Eptifibatide Acetate is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue. A disulfide bridge forms between mercaptopropionyl and cysteine. Eptifibatide prevents platelet aggregation. One study shows the inhibition of platelet glycoprotein IIb/IIIa in acute coronary syndromes.",{"v":832.4,"d":"832.40"},"148031-34-9","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://selleckchem.com/products/eptifibatide-acetate.html","C35H49N11O9S2","Acetate","Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2","NC(=N)NCCCCC1NC(=O)CCSSCC(NC(=O)C2CCCN2C(=O)C(CC3=C[NH]C4=C3C=CC=C4)NC(=O)C(CC(O)=O)NC(=O)CNC1=O)C(N)=O",{"v":0,"d":"0.000"},0,0,0]
["P1017","Octreotide (SMS 201-995) acetate","e8","L3800-51","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017","Preregistration","N/A","Neuronal Signaling","Octreotide (SMS 201-995) acetate is the acetate salt of a cyclic octapeptide. It is a long-acting octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin.","1019.28 (free base)","79517-01-4","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://selleckchem.com/products/octreotide-acetate.html","C49H66N10O10S2.xC2H4O2","Acetate","D-Phe-c[Cys-Phe-D-Trp-Lys-Thr-Cys]-Thr-ol","CC(O)C(CO)NC(=O)C1CSSCC(NC(=O)C(N)CC2=CC=CC=C2)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=C[NH]C5=C4C=CC=C5)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)N1",{"v":0,"d":"0.000"},0,0,0]
["P1025","Atosiban Acetate","f8","L3800-51","in 10mM Water","CFDA,HMA","Martindale:The Extra Pharmacopoeia","Marketed","N/A","Angiogenesis","Atosiban Acetate is a competitive oxytocin and vasopressin antagonist by exhibiting high affinity for both receptors. It is used to treat preterm labors.",{"v":994.2,"d":"994.20"},"90779-69-4","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://www.selleckchem.com/peptide/atosiban-acetate.html","C43H67N11O12S2","Acetate","c[Mpr-D-Tyr(OEt)-Ile-Thr-Asn-Cys]-Pro-Orn-Gly-NH2","CCOC1=CC=C(CC2NC(=O)CCSSCC(NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(NC2=O)C(C)CC)C(C)O)C(=O)N3CCCC3C(=O)NC(CCCN)C(=O)NCC(N)=O)C=C1",{"v":0,"d":"0.000"},0,0,0]
["P1029","Oxytocin (Syntocinon)","g8","L3800-51","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,BP2017,JP17,IP2010","N/A","N/A","Angiogenesis","Oxytocin(Syntocinon) is a nine amino acid peptide that is synthesized in hypothalamic neurons and transported down axons of the posterior pituitary for secretion into blood.",{"v":1067.2,"d":"1067.20"},"50-56-6","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://selleckchem.com/products/Oxytocin-Acetate(Syntocinon).html","C45H70N12O14S2","Free Base","H-Cys(1)-Tyr-Ile-Gln-Asn-Cys(1)-Pro-Leu-Gly-NH2","CCC(C)C1NC(=O)C(CC2=CC=C(O)C=C2)NC(=O)C(N)CSSCC(NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC1=O)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(N)=O.CC(O)=O",{"v":0,"d":"0.000"},0,0,0]
["P1030","Salmon Calcitonin Acetate","h8","L3800-51","in 10mM Water","DMF,EMA","N/A","N/A","N/A","N/A","Salmon Calcitonin Acetate, which is more potent and longer lasting than human CT, has been used widely for the treatment of osteoporosis, paget's disease, hypercalcemic shock and chronic pain in terminal cancer patients.",3431.85,"47931-85-1","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://www.selleckchem.com/peptide/salmon-calcitonin-acetate.html","C145H240N44O48S2","Acetate","N/A","CC(C)CC(NNC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)C(=O)C(CC1=CC=C(O)C=C1)NN2CCCC2C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)O)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CO)C(=O)NCC(=O)NC(C(C)O)C(=O)N3CCCC3C(N)=O)C(=O)C(=O)C(CCCCN)NC(=O)C(CC4=CN=C[NH]4)NC(=O)C(CC(C)C)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(N)=O)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(NC(=O)C5CSSCC(N)C(=O)NC(CO)C(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)N5)C(C)C",{"v":0,"d":"0.000"},0,0,0]
["P1034","Terlipressin Acetate","a9","L3800-51","in 10mM Water","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia","Marketed","5-alpha Reductase","Angiogenesis","Terlipressin Acetate is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. It has been found to be effective when norepinephrine does not help.",1227.37,"14636-12-5","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://selleckchem.com/products/terlipressin-acetate.html","C52H74N16O15S2","Acetate","Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2(Cys4-Cys9)","NCCCCC(NC(=O)C1CCCN1C(=O)C2CSSCC(NC(=O)CNC(=O)CNC(=O)CN)C(=O)NC(CC3=CC=C(O)C=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)N2)C(=O)NCC(N)=O","N/A","N/A","N/A","N/A"]
["P1039","Somatostatin Acetate","b9","L3800-51","in 10mM Water","CFDA,DMF","Martindale the Extra Pharmacopoei","Phase 3","5-alpha Reductase","Neuronal Signaling","Somatostatin Acetate is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones.",1637.88,"38916-34-6",{"v":-1,"d":"-1.00"},"N/A",{"v":100,"d":"100.00"},61.05,"http://www.selleck.cn/products/somatostatin-acetate.html","C76H104N18O19S2","Free Base","Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH(Cys3-Cys14)","CC(N)C(=O)NCC(=O)NC1CSSCC(NC(=O)C(CO)NC(=O)C(NC(=O)C(CC2=CC=CC=C2)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(CC3=C[NH]C4=CC=CC=C34)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(CC6=CC=CC=C6)NC(=O)C(CC(N)=O)NC(=O)C(CCCCN)NC1=O)C(C)O)C(C)O)C(O)=O.CC(O)=O",-8.729,16,21,26]
["P1049","GHRP-2","c9","L3800-51","in 10mM Water","marketed in Japan","N/A","Marketed","N/A","N/A","GHRP-2 is a true hGH secretagogue. It is a synthetic agonist of ghrelin.",{"v":878,"d":"878.00"},"158861-67-7","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://selleckchem.com/products/GHRP-2-Acetate.html","C47H59N9O8","Free Base","N/A","CC(N)C(=O)NC(CC1=CC=C2C=CC=CC2=C1)C(=O)NC(CC3=C[NH]C4=C3C=CC=C4)C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCCCN)C(N)=O",{"v":0,"d":"0.000"},0,0,0]
["P1084","Desmopressin Acetate","d9","L3800-51","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37","Marketed","Vasopressin Receptor","GPCR & G Protein","Desmopressin is a synthetic octapeptide, and an analogue of human hormone arginine vasopressin with antidiuretic and coagulant activities. It is a selective agonist for the vasopressin V2 receptor (V2R).",1129.27,"62288-83-9","N/A","N/A","N/A",{"v":10,"d":"10.00"},"https://www.selleckchem.com/products/desmopressin-acetate-.html","C46H64N14O12S2.C2H4O2","Acetate","N/A","CC(O)=O.NC(=N)NCCCC(NC(=O)C1CCCN1C(=O)C2CSSCCC(=O)NC(CC3=CC=C(O)C=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)N2)C(=O)NCC(N)=O",{"v":0,"d":"0.000"},0,0,0]
["P1085","Angiotensin II human Acetate","e9","L3800-51","in 10mM Water","DMF","N/A","Marketed","Angiotensin Receptor","GPCR & G Protein","Angiotensin II (angII) is an octapeptide hormone which affects the activities of heart, kidney, vasculature and brain. It works via binding to specific receptors present on cell membranes.",1106.23,"68521-88-0","N/A","N/A","N/A",{"v":10,"d":"10.00"},"https://www.selleckchem.com/products/angiotensin-ii-human-acetate.html","C52H75N13O14","Acetate","N/A","CCC(C)C(NC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C(NC(=O)C(CCCNC(N)=N)NC(=O)C(N)CC(O)=O)C(C)C)C(=O)NC(CC2=C[NH]C=N2)C(=O)N3CCCC3C(=O)NC(CC4=CC=CC=C4)C(O)=O.CC(O)=O",{"v":0,"d":"0.000"},0,0,0]
["P1087","Carperitide Acetate","f9","L3800-51","in 10mM Water","DMF,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Others","Others","Caperitide acetate is a synthetic analog of human atrial natriuretic peptide (ANP) containing 28 amino acids. It acts as an inhibitor of endothelin-1 secretion when stimulated by angiotensin II (Ang II), likely through a cGMP-dependent mechanism.It induces natriuresis, diuresis, and vasodilation, effectively reducing blood volume and easing cardiac strain. By suppressing the renin-angiotensin-aldosterone system (RAAS), it aids in preventing myocardial remodeling and fibrosis, thereby enhancing cardiac function and decreasing the incidence of postoperative atrial fibrillation, heart failure, and stroke. Carperitide acetate inhibits endothelin-1 secretion in a dose-dependent way.",3140.49,"1366000-58-9","N/A","N/A","N/A",{"v":10,"d":"10.00"},"https://www.selleckchem.com/products/carperitide-acetate.html","C129H207N45O41S3","free base","N/A","CCC(C)C1NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(O)=O)NC(=O)C(CCSC)NC(=O)C(CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=CC=C2)NC(=O)C(CSSCC(NC(=O)CNC(=O)C(CC(C)C)NC(=O)CNC(=O)C(CO)NC(=O)C(CCC(N)=O)NC(=O)C(C)NC(=O)CNC1=O)C(=O)NC(CC(N)=O)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC4=CC=C(O)C=C4)C(O)=O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(C)C)NC(=O)C(N)CO.CC(O)=O",-19.837,32,46,75]
["S1671","(6-)ε-​Aminocaproic acid","g9","L3800-51","in 10mM Water","DMF","N/A","N/A","Others","Others","(6-)ε-​Aminocaproic acid is a derivative and analogue of the amino acid lysine.",131.17,"60-32-2","N/A","N/A",{"v":26,"d":"26.00"},198.22,"http://selleckchem.com/products/Aminocaproic-acid(Amicar).html","C6H13NO2","free base","N/A","NCCCCCC(O)=O",-2.164,1,1,5]
["S3076","Foscarnet Sodium","h9","L3800-51","in 10mM Water","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,EP9.2,USP39-NF34,BP2015","N/A","Reverse Transcriptase","Microbiology","Foscarnet Sodium (Phosphonoformate) inhibits viral RNA polymerases, reverse transcriptase, and DNA polymerases through noncompetitive inhibition with dNTPs.",191.95,"63585-09-1","N/A","N/A",{"v":3,"d":"3.00"},15.63,"http://selleckchem.com/products/foscarnet-sodium.html","CNa3O5P","Sodium","Phosphonoformate","[Na+].[Na+].[Na+].[O-]C(=O)[P]([O-])([O-])=O",-4.033,0,0,1]
["S4519","Citric acid trilithium salt tetrahydrate","a10","L3800-51","in 10mM Water","FDA,DMF,HAHA,NDC,PMDA,HMA","N/A","N/A","Others","Others","Citric acid trilithium salt tetrahydrate (Trilithium citrate tetrahydrate, Lithium citrate tribasic tetrahydrate) is a pharmaceutical and construction material. It is commonly used in HPLC gradient elution for quantification of amino acids.",281.98,"6080-58-6","N/A","N/A",{"v":56,"d":"56.00"},{"v":198.6,"d":"198.60"},"http://selleckchem.com/products/citric-acid-trilithium-salt-tetrahydrate.html","C6H5Li3O7&bull;4H2O","free base","Trilithium citrate tetrahydrate, Lithium citrate tribasic tetrahydrate","O.O.O.O.[Li]OC(=O)CC(O)(CC(=O)O[Li])C(=O)O[Li]",-1.875,6,0,8]
["S5865","Hyaluronic acid","b10","L3800-51","in 10mM Water","DMF,CFDA,NDC","Martindale:The Extra Pharmacopoeia","Marketed","Others","Others","Hyaluronic acid (HA, Hyaluronan, Hyaluronate) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is widely used in skin care.","N/A","9004-61-9","N/A","N/A",{"v":5,"d":"5.00"},"N/A","http://www.selleckchem.com/products/hyaluronic-acid.html","N/A","Free Base","Hyaluronan, Hyaluronate","CC(=O)NC1C(O[*])C(O)C(CO)OC1OC2C(O)C(O)C(O[*])OC2C(O)=O",-2.747,7,5,7]
["S4986","Latamoxef sodium","c10","L3800-51","in 10mM Water","CFDA,PMDA","KP Ⅹ,JP17","N/A","Antibiotics,Bacterial","Microbiology","Latamoxef sodium (Moxalactam Disodium, FestamoxinLy, Shiomarin, Ly 127935, 6059 S) is an antibiotic and has anti-bacterial and anti-inflammation effects.",564.44,"64953-12-4","N/A","N/A","N/A",{"v":10,"d":"10.00"},"https://www.selleckchem.com/products/latamoxef-sodium.html","C20H18N6Na2O9S","Sodium","Moxalactam Disodium, FestamoxinLy, Shiomarin, Ly 127935, 6059 S","[Na+].[Na+].COC1(NC(=O)C(C([O-])=O)C2=CC=C(O)C=C2)C3OCC(=C(N3C1=O)C([O-])=O)CSC4=NN=N[N]4C",-3.547,7,2,9]
["S2441","Estramustine phosphate sodium","d10","L3800-51","in 10mM Water","FDA,NDC,DMF","Martindale the Extra Pharmacopoei","N/A","Microtubule Associated","Cytoskeletal Signaling","Estramustine phosphate sodium (EMP, Emcyt, Estracyt) is an antitumour drug with a unique dual mode of action. Estrone and estradiol, products of the metabolism of estramustine phosphate sodium, have shown antigonadotrophic activity resulting in reduced testosterone levels. Estramustine(the cytotoxic metabolite produced by dephosphorylation of estramustine phosphate sodium) is an antiprostatic tumor drug with antimicrotubule effects.",564.35,"52205-73-9","<1","N/A",{"v":100,"d":"100.00"},{"v":177.2,"d":"177.20"},"http://www.selleck.cn/products/estramustine-phosphate-sodium.html","C23H30Cl2NNa2O6P","phosphate sodium","EMP, Emcyt, Estracyt","[Na+].[Na+].CC12CCC3C(CCC4=C3C=CC(=C4)OC(=O)N(CCCl)CCCl)C1CCC2O[P]([O-])([O-])=O",3.131,3,0,8]
["S3948","Spermine","e10","L3800-51","in 10mM Water","NDC","N/A","N/A","Others","Others","Spermine (4,9-Diaza-1,12-dodecanediamine) is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria.",202.34,"71-44-3","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://selleckchem.com/products/spermine.html","C10H26N4","free base","4,9-Diaza-1,12-dodecanediamine","NCCCNCCCCNCCCN",-1.504,0,4,11]
["S2433","DL-Buthionine-Sulfoximine","f10","L3800-51","in 10mM Water","N/A","N/A","Phase 1","Glutathione","Metabolism","DL-Buthionine-Sulfoximine (BSO, DL-Buthionine-(S,R)-sulfoximine) is an inhibitor of glutathione (GSH) synthesis.",222.31,"5072-26-4","<1","N/A",{"v":44,"d":"44.00"},197.92,"http://www.selleckchem.com/products/dl-buthionine-sulfoximine.html","C8H18N2O3S","Free Base","BSO, DL-Buthionine-(S,R)-sulfoximine","CCCC[S](=N)(=O)CCC(N)C(O)=O",{"v":-2.18,"d":"-2.180"},2,1,7]
["S2435","Sodium stibogluconate","g10","L3800-51","in 10mM Water","CFDA","Martindale:The Extra Pharmacopoeia, BP2020, Ph.Int_6th , IP2010","N/A","phosphatase","Metabolism","Sodium stibogluconate (SSG, Stibogluconate trisodium nonahydrate, Lenocta, VQD-001), a pentavalent antimony derivative, is a potent and selective inhibitor of protein tyrosine phosphatase (PTPase). Sodium stibogluconate inhibits 99% of Src homology 2 domain-containing phosphatase 1 (SHP-1) activity at 10 μg/ml and similar degrees of inhibition of SHP-2 and PTP1B requires 100 μg/ml. Sodium stibogluconate is a drug used in treatment of leishmaniasis.",907.88,"16037-91-5","<1","N/A",{"v":20,"d":"20.00"},22.03,"http://www.selleckchem.com/products/sodium-stibogluconate.html","C12H35Na3O26Sb2","Sodium","SSG, Stibogluconate sodium, Stibogluconate trisodium nonahydrate, Lenocta, VQD-001","O.O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+].OCC(O)C1O[Sb]2(O)(OC1C(O2)C([O-])=O)O[Sb]34([O-])OC(C(O)CO)C(O3)C(O4)C([O-])=O",-8.931,7,4,8]
["S6831","HEPES","h10","L3800-51","in 10mM Water","DMF","N/A","N/A","Others","Others","HEPES is a zwitterionic sulfonic acid buffering agent, commonly used to uphold a neutral pH of basal medium within cell cultures.",{"v":238.3,"d":"238.30"},"7365-45-9","<1","N/A",{"v":48,"d":"48.00"},201.43,"http://www.selleckchem.com/products/hepes.html","C8H18N2O4S","Free Base","4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid","OCCN1CCN(CC1)CC[S](O)(=O)=O",-0.858,0,1,5]
["S8670","Vipivotide tetraxetan (PSMA-617)","a11","L3800-51","in 10mM Water","N/A","N/A","Phase 3","Drug-Linker Conjugates for ADC","Others","Vipivotide tetraxetan (PSMA-617) is a chemically modified PSMA(prostate-specific membrane antigen) inhibitor with a Ki of 0.37 nM.",1042.14,"1702967-37-0",{"v":-1,"d":"-1.00"},-0.96,{"v":100,"d":"100.00"},95.96,"http://www.selleckchem.com/products/vipivotide-tetraxetan.html","C49H71N9O16","Free Base","N/A","OC(=O)CCC(NC(=O)NC(CCCCNC(=O)C(CC1=CC2=CC=CC=C2C=C1)NC(=O)C3CCC(CC3)CNC(=O)CN4CCN(CCN(CCN(CC4)CC(O)=O)CC(O)=O)CC(O)=O)C(O)=O)C(O)=O",-11.549,10,5,27]
["S4933","Lithium carbonate","b11","L3800-51","in 10mM Water","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017,Ph.Int_5th,IP2010","Marketed","Dopamine Receptor","Neuronal Signaling","Lithium carbonate (Li2CO3) is an inorganic compound that is valuable and effective agent in the treatment and prophylaxis of mood disorders, particularly bipolar disorder (BD). Lithium carbonate is able to alter D2 dopamine receptors response.",73.89,"554-13-2","N/A","N/A","N/A",{"v":10,"d":"10.00"},"https://www.selleckchem.com/products/lithium-carbonate.html","CLi2O3","Salt","Li2CO3","[LiH].[Li]OOC=O",-0.347,2,0,2]
["S3203","D-Alanine","c11","L3800-51","in 10mM Water","DMF","N/A","N/A","NMDAR","Neuronal Signaling","D-alanine (Ala, (R)-Alanine, Ba 2776, D-α-Alanine, NSC 158286) is an endogenous co-agonist at the glycine site of the N-methyl-d-aspartate (NMDA) receptor.",89.09,"338-69-2","<1","N/A",{"v":18,"d":"18.00"},202.04,"http://www.selleckchem.com/products/d-alanine.html","C3H7NO2","free base","Ala, (R)-Alanine, Ba 2776, D-α-Alanine, NSC 158286","CC(N)C(O)=O",-3.161,1,1,1]
["S9665","Motixafortide (BL-8040)","d11","L3800-51","in 10mM Water","N/A","N/A","Phase 3","Apoptosis related,Bcl-2,CDK,CXCR,ERK,MicroRNA","Immunology & Inflammation","Motixafortide (BL-8040, BKT140, TF 14016, 4-fluorobenzoyl, 4F-benzoyl-TN14003, T140) is an antagonist of CXCR4 with IC50 of ～1 nM. BL-8040 induces the apoptosis of AML blasts by down-regulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression.",2159.52,"664334-36-5",{"v":-1,"d":"-1.00"},-0.46,{"v":100,"d":"100.00"},46.31,"http://www.selleckchem.com/products/motixafortide-bl-8040-.html","C97H144FN33O19S2","free base","BKT140, TF 14016, 4-fluorobenzoyl, 4F-benzoyl-TN14003, T140","NCCCCC1NC(=O)C(CCCNC(N)=O)NC(=O)C(CC2=CC=C(O)C=C2)NC(=O)C(CSSCC(NC(=O)C(CCCNC(N)=O)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC3=CC=C(O)C=C3)NC(=O)C4CCCN4C(=O)C(CCCCN)NC1=O)C(=O)NC(CCCNC(N)=N)C(N)=O)NC(=O)C(CC5=CC6=CC=CC=C6C=C5)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCCNC(N)=N)NC(=O)C7=CC=C(F)C=C7",-3.895,17,30,53]
["P1088","Lanreotide acetate","e11","L3800-51","in 10mM Water","DMF, NDC, FDA","N/A","Marketed","GHSR","Endocrinology & Hormones","Lanreotide (Laromustine, Angiopeptin, BIM 23014, Dermopeptin, Ipstyl, ITM-014, Somatulina, Somatuline, Lanreotidum) acetate, an analog of the native somatostatin peptide, is a physiological inhibitor of growth hormone (GH). Lanreotide also has antitumoral effects.",1156.38,"2378114-72-6",{"v":-1,"d":"-1.00"},"N/A",{"v":23,"d":"23.00"},19.89,"https://www.selleckchem.com/products/lanreotide-acetate.html","C56H73N11O12S2","Acetate","Laromustine, Angiopeptin, BIM 23014, BIM 23014C, BM 23014, Dermopeptin, Ipstyl, ITM-014, ITM-014T, Somatulina, Somatuline, Lanreotidum","CC(C)C1NC(=O)C(CCCCN)NC(=O)C(CC2=C[NH]C3=C2C=CC=C3)NC(=O)C(CC4=CC=C(O)C=C4)NC(=O)C(CSSCC(NC1=O)C(=O)NC(C(C)O)C(N)=O)NC(=O)C(N)CC5=CC6=CC=CC=C6C=C5.CC(O)=O",-0.979,9,13,17]
["S3096","L-Histidine monohydrochloride monohydrate","f11","L3800-51","in 10mM Water","DMF, NDC","USP43-NF38, JP17","N/A","Others","Metabolism","L-Histidine monohydrochloride monohydrate (L-Histidine hydrochloride hydrate, H-His-OH.HCl.H2O), a structural analogue of the essential amino acid L-histidine, is a reversible inhibitor of protein biosynthesis which evokes disparate responses from non-tumorigenic and tumorigenic cells in culture.",209.63,"5934-29-2","<1","N/A",{"v":42,"d":"42.00"},200.35,"https://www.selleckchem.com/products/l-histidine-monohydrochloride-monohydrate.html","C6H12ClN3O3","Monohydrate","L-Histidine hydrochloride hydrate, H-His-OH.HCl.H2O","O.Cl.NC(CC1=CN=C[NH]1)C(O)=O",-3.538,2,2,3]
["S3142","Potassium sorbate","g11","L3800-51","in 10mM Water","N/A","EP10.4, USP43-NF38, IP2010","N/A","Bacterial","Microbiology","Potassium sorbate (Sorbic acid potassium) is a nonpoisonous food preservative isolated from Sorbus aucuparia. Potassium sorbate is an effective inhibitor of most molds and yeasts and some bacteria.",150.22,"24634-61-5","<1","N/A",{"v":30,"d":"30.00"},199.71,"https://www.selleckchem.com/products/potassium-sorbate.html","C6H7KO2","Potassium","Sorbic acid potassium","[K+].C/C=C/C=C/C([O-])=O",-0.111,0,0,2]
["S3327","Disodium 5'-inosinate monohydrate","h11","L3800-51","in 10mM Water","N/A","N/A","Phase 2","Others","Others","Disodium 5'-inosinate monohydrate (Inosine 5'-monophosphate disodium salt hydrate) is an endogenous metabolite.",410.18,"352195-40-5","<1","N/A",{"v":82,"d":"82.00"},199.91,"https://www.selleckchem.com/products/disodium-5-inosinate-monohydrate.html","C10H13N4Na2O9P","Monohydrate","Inosine 5'-monophosphate disodium salt hydrate","O.[Na+].[Na+].OC1C(O)C(OC1CO[P]([O-])([O-])=O)[N]2C=NC3=C2N=CNC3=O",-4.705,5,3,4]
["S3346","1-Methylnicotinamide chloride","a2","L3800-52","in 10mM Water","N/A","N/A","Phase 3","Prostaglandin Receptor","GPCR & G Protein","1-Methylnicotinamide (1-MNA, 3-Carbamoyl-1-methylpyridin-1-ium, Trigonellamide) chloride is an active endogenous metabolite of nicotinamide that exhibits anti-inflammatory and anti-thrombotic activities. 1-Methylnicotinamide enhances tumor vasculature formation and markedly increases prostacyclin (PGI2) generation.",172.61,"1005-24-9","<1","N/A",{"v":35,"d":"35.00"},202.77,"https://www.selleckchem.com/products/1-methylnicotinamide-chloride.html","C7H9ClN2O","Chloride","1-MNA, 3-Carbamoyl-1-methylpyridin-1-ium chloride, Trigonellamide chloride","[Cl-].C[N+]1=CC=CC(=C1)C(N)=O",-2.237,1,1,1]
["P1033","Teriparatide Acetate","b2","L3800-52","in 10mM Water","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","EP10.4, USP43-NF38","N/A","5-alpha Reductase","Angiogenesis","Teriparatide Acetate is a recombinant form of parathyroid hormone, used in the treatment of some forms of osteoporosis",4117.72,"52232-67-4",{"v":-1,"d":"-1.00"},"N/A",{"v":100,"d":"100.00"},24.29,"http://www.selleckchem.com/peptide/teriparatide-acetate.html","C181H291N55O51S2","Free Base","H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH","CCC(C)C(NC(=O)C(CCC(O)=O)NC(=O)C(CO)NC(=O)C(NC(=O)C(N)CO)C(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(CC1=CN=C[NH]1)C(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC2=CN=C[NH]2)C(=O)NC(CC(C)C)C(=O)NC(CC(N)=O)C(=O)NC(CO)C(=O)NC(CCSC)C(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)C)C(=O)NC(CCC(O)=O)C(=O)C(=O)C(CC3=C[NH]C4=C3C=CC=C4)NC(=O)C(CC(C)C)NNC(CCCNC(N)=N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CC(O)=O)C(=O)NC(C(C)C)C(=O)NC(CC5=CN=C[NH]5)C(=O)NC(CC(N)=O)C(=O)NC(CC6=CC=CC=C6)C(O)=O.CC(O)=O",-24.309,47,53,148]
["P1047","Felypressin Acetate","c2","L3800-52","in 10mM Water","N/A","EP10.5","N/A","5-alpha Reductase","Angiogenesis","Felypressin-Acetate is a non-catecholamine vasoconstrictor that is chemically associated to vasopressin, the posterior pituitary hormone.",1040.22,"56-59-7",{"v":-1,"d":"-1.00"},"N/A",{"v":100,"d":"100.00"},96.13,"http://www.selleckchem.com/peptide/felypressin-acetate.html","C46H65N13O11S2","Free Base","H-[Cys-Phe-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2","NCCCCC(NC(=O)C1CCCN1C(=O)C2CSSCC(N)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)N2)C(=O)NCC(N)=O",-3.938,11,12,19]
["P1201","LL37 (Human cathelicidin)","d2","L3800-52","in 10mM Water","N/A","N/A","Phase 2","Anti-infection","Immunology & Inflammation","LL37 (Human cathelicidin, Ropocamptide) is a cathelicidin-related antimicrobial peptide with potent chemotactic and immunomodulatory properties.",4493.26,"154947-66-7",{"v":-1,"d":"-1.00"},"N/A",{"v":50,"d":"50.00"},11.13,"http://www.selleckchem.com/products/ll37-human.html","C205H340N60O53","Free Base","Ropocamptide","CCC(C)C(NC(=O)C(CCCCN)NC(=O)C(CCC(O)=O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CC(C)C)NNC(CC(C)C)C=O)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCC(O)=O)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCCN)C(=O)NC(CCCNC(N)=N)C(=O)C(=O)C(NNC(C(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CC(O)=O)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)N5CCCC5C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)O)C(=O)NC(CCC(O)=O)C(=O)C(=O)C(CO)NO)C(C)CC",-23.142,44,57,171]
["S1314","Zoledronic acid (ZOL 446)","e2","L3800-52","in 10mM Water","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","EP10.4, IP2010","Marketed","Apoptosis related,Autophagy,Ras,Rho","Cell Cycle","Zoledronic acid (ZA, Zoledronate, CGP-4244, GP42446A, ZOL 446, Zometa, Zomera, Aclasta, Reclast), a potent osteoclast inhibitor, induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho. Zoledronic acid (ZA) also induces autophagy.",272.09,"118072-93-8","<1","N/A",{"v":4,"d":"4.00"},{"v":14.7,"d":"14.70"},"http://www.selleckchem.com/products/Zoledronic-Acid.html","C5H10N2O7P2","Free Base","ZA, Zoledronate, CGP-4244, GP42446A, ZOL 446, Zometa, Zomera, Aclasta, Reclast","OC(C[N]1C=CN=C1)([P](O)(O)=O)[P](O)(O)=O",-1.209,1,0,4]
["S3497","Gadobutrol","f2","L3800-52","in 10mM Water","FDA, DMF, PMDA","EP10.5","Marketed","Others","Others","Gadobutrol (Gadovist, Gadavist,ZK 135079) is a non-ionic macrocyclic gadolinium-based contrast agent (GBCA) that is usedfor tissue contrast enhancement in magnetic resonance imaging (MRI).",604.71,"138071-82-6","<1","N/A",{"v":100,"d":"100.00"},165.37,"http://www.selleckchem.com/products/gadobutrol.html","C18H31GdN4O9","Free Base","Gadovist, Gadavist,ZK 135079","[Gd+3].OCC(O)C(CO)N1CCN(CCN(CCN(CC1)CC([O-])=O)CC([O-])=O)CC([O-])=O",-6.984,0,3,10]
["S4383","Bekanamycin","g2","L3800-52","in 10mM Water","N/A","JP17","N/A","Others","Others","Bekanamycin is an aminoglycoside antibiotic.",483.51,"4696-76-8","<1","N/A",{"v":96,"d":"96.00"},198.55,"http://www.selleckchem.com/products/bekanamycin.html","C18H37N5O10","Free Base","Kanamycin B","NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)C(O)C1O",-7.433,4,11,6]
["S4443","Piperazine adipate","h2","L3800-52","in 10mM Water","DMF","EP10.4, USP42-NF37, KP Ⅹ, Ph.Int_6th, JP16,IP2010","N/A","Parasite","Microbiology","Piperazine adipate is a broad spectrum anthelmintic agent that inhibits malate oxidation in Ascaridia galli and Heterakis gallinae.",232.28,"142-88-1","<1","N/A",{"v":43,"d":"43.00"},185.12,"http://www.selleckchem.com/products/piperazine-adipate.html","C10H20N2O4","Free Base","N/A","OC(=O)CCCCC(O)=O.C1CNCCN1",-5.651,2,2,5]
["S4494","Methionine","a3","L3800-52","in 10mM Water","DMF, CFDA, NDC","EP10.5, USP43-NF38,","Discontinued","GABA Receptor","Neuronal Signaling","Methionine (MRX-1024, D-Methionine) is an activitor of GABAA receptor that modulates neuronal activity.",149.21,"348-67-4","<1","N/A",{"v":29,"d":"29.00"},194.36,"http://www.selleckchem.com/products/methionine.html","C5H11NO2S","Free Base","MRX-1024, D-Methionine","CSCCC(N)C(O)=O",-2.834,1,1,4]
["S4857","L-Ornithine","b3","L3800-52","in 10mM Water","DMF, CFDA, NDC","N/A","N/A","Others","Others","L-ornithine ((S)-2,5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle.",132.16,"70-26-8","<1","N/A",{"v":26,"d":"26.00"},196.73,"http://www.selleckchem.com/products/l-ornithine.html","C5H12N2O2","Free Base","(S)-2,5-Diaminopentanoic acid","NCCCC(N)C(O)=O",-3.697,1,2,4]
["S4879","Tenofovir hydrate","c3","L3800-52","in 10mM Water","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","Ph.Int_6th, IP2010","Phase 3","Antiviral,Reverse Transcriptase","Microbiology","Tenofovir (GS-1278) hydrate blocks reverse transcriptase and hepatitis B virus infections.",305.23,"206184-49-8","<1","N/A",{"v":10,"d":"10.00"},32.76,"http://www.selleckchem.com/products/tenofovir-hydrate.html","C9H16N5O5P","Hydrate","GS-1278 hydrate","O.CC(C[N]1C=NC2=C(N)N=CN=C12)OC[P](O)(O)=O",-0.979,4,1,5]
["S5000","Gadodiamide","d3","L3800-52","in 10mM Water","FDA, DMF, NDC, PMDA","EP10.5, USP43-NF38","N/A","Others","Others","Gadodiamide (GDD, Omniscan) is a widely used magnetic resonance imaging (MRI) contrast agent with a high renal toxicity.",573.66,"131410-48-5","<1","N/A",{"v":100,"d":"100.00"},174.32,"http://www.selleckchem.com/products/gadodiamide.html","C16H26GdN5O8","Free Base","Omniscan, GDD","[Gd+3].CNC(=O)CN(CCN(CCN(CC([O-])=O)CC(=O)NC)CC([O-])=O)CC([O-])=O",-7.261,2,2,16]
["S5022","Varenicline Hydrochloride","e3","L3800-52","in 10mM Water","FDA, DMF, EMA, NDC, PMDA","N/A","Marketed","AChR","Neuronal Signaling","Varenicline (CP 526555) Hydrochloride is a potent and selective inhibitor of nicotine acetylcholine receptor (nAChR) with Ki of 0.12 nM and 0.14 nM for α6β2 nAChR and α4β2 nAChR, respectively.",247.72,"230615-23-3","<1","N/A",{"v":50,"d":"50.00"},201.84,"http://www.selleckchem.com/products/varenicline-hydrochloride.html","C13H14ClN3","Hydrochloride","CP 526555 hydrochloride","Cl.C1NCC2CC1C3=CC4=NC=CN=C4C=C23",{"v":1.42,"d":"1.420"},2,1,0]
["S5198","Sodium Etidronate","f3","L3800-52","in 10mM Water","FDA, DMF, CFDA, PMDA","EP10.5, USP43-NF38, JP17","N/A","phosphatase","Metabolism","Sodium Etidronate (Didronel, EHDP, Etidronic acid) is a non-aminobisphosphonate that exhibits protein tyrosine phosphatase (PTP) inhibitory activity.",249.99,"7414-83-7","<1","N/A",{"v":50,"d":"50.00"},200.01,"http://www.selleckchem.com/products/sodium-etidronate.html","C2H6Na2O7P2","Sodium","Didronel, EHDP, Etidronic acid","[Na+].[Na+].CC(O)([P](O)([O-])=O)[P](O)([O-])=O",-3.649,0,0,2]
["S5260","ATP","g3","L3800-52","in 10mM Water","DMF, NDC","N/A","No development reported","Immunology & Inflammation related","Immunology & Inflammation","ATP (Adenosine-Triphosphate, Adenosine 5'-triphosphate) is a multifunctional nucleoside triphosphate and an important endogenous signaling molecule in immunity and inflammation.",507.18,"56-65-5","<1","N/A",{"v":100,"d":"100.00"},197.17,"http://www.selleckchem.com/products/atp.html","C10H16N5O13P3","Free Base","Adenosine-Triphosphate, Adenosine 5'-triphosphate","NC1=C2N=C[N](C3OC(CO[P](O)(=O)O[P](O)(=O)O[P](O)(O)=O)C(O)C3O)C2=NC=N1",-2.526,7,3,8]
["S5330","Amikacin Sulfate Salt","h3","L3800-52","in 10mM Water","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","EP10.5, USP43-NF38, KP Ⅹ, Ph.Int_6th, JP17, IP2010","Discontinued","Antibiotics,Bacterial","Microbiology","Amikacin (BAY 41-6551) sulfate, a semisynthetic analog of kanamycin, is an aminoglycoside antibiotic which is very active against most gram-negative bacteria including gentamicin- and tobramycin-resistant strains.",683.68,"149022-22-0","<1","N/A",{"v":100,"d":"100.00"},146.27,"http://www.selleckchem.com/products/amikacin-sulfate-salt.html","C22H45N5O17S","Sulfate Salt","BAY 41-6551 sulfate","NCCC(O)C(=O)NC1CC(N)C(OC2OC(CN)C(O)C(O)C2O)C(O)C1OC3OC(CO)C(O)C(N)C3O.O[S](O)(=O)=O",-9.033,5,13,10]
["S5956","Dexamethasone phosphate disodium","a4","L3800-52","in 10mM Water","FDA, DMF, EMA, HMA, CFDA, NDC, PMDA","USP42-NF37, KP Ⅹ, Ph.Int_6th, JP17, Ph.Int_5th, JP16, IP2010","N/A","Glucocorticoid Receptor","Endocrinology & Hormones","Dexamethasone phosphate disodium (DEX, Dexacort, Decadron, Dexair, Hexadrol, Maxidex) is a glucocorticoid receptor agonist with both anti-inflammatory and anti-oxidative effects.",{"v":516.4,"d":"516.40"},"2392-39-4","<1","N/A",{"v":100,"d":"100.00"},193.65,"http://www.selleckchem.com/products/dexamethasone-phosphate-disodium.html","C22H28FNa2O8P","Disodium","DEX, Dexacort, Decadron, Dexair, Hexadrol, Maxidex, Dexamethasone 21-phosphate disodium salt","[Na+].[Na+].CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO[P]([O-])([O-])=O",-0.541,3,1,4]
["S5964","Gatifloxacin hydrochloride","b4","L3800-52","in 10mM Water","FDA, DMF, CFDA, NDC, PMDA","IP2010","Marketed","Topoisomerase","DNA Damage/DNA Repair","Gatifloxacin (AM-1155, CG5501, BMS-206584, PD135432) hydrochloride is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases with IC50 of 13.8 μg/ml and 0.109 μg/ml for S. aureus topoisomerase IV and E. coli DNA gyrase, respectively.",411.86,"121577-32-0",{"v":4,"d":"4.00"},9.71,{"v":20,"d":"20.00"},48.56,"http://www.selleckchem.com/products/gatifloxacin-hydrochloride.html","C19H23ClFN3O4","Hydrochloride","AM-1155 hydrochloride, CG5501 hydrochloride, BMS-206584 hydrochloride, PD135432 hydrochloride","Cl.COC1=C2N(C=C(C(O)=O)C(=O)C2=CC(=C1N3CCNC(C)C3)F)C4CC4",-0.527,3,1,4]
["S5968","Kasugamycin hydrochloride hydrate","c4","L3800-52","in 10mM Water","CFDA","N/A","N/A","Antibiotics","Immunology & Inflammation","Kasugamycin (Ksg) hydrochloride hydrate, an antibiotic which binds both the 30S and 70S ribosome, specifically inhibits translation initiation of canonical but not of leaderless messenger RNAs.",433.84,"200132-83-8","<1","N/A",{"v":87,"d":"87.00"},200.53,"http://www.selleckchem.com/products/kasugamycin-hydrochloride-hydrate.html","C14H28ClN3O10","Hydrochloride hydrate","Ksg hydrochloride hydrate","O.Cl.CC1OC(OC2C(O)C(O)C(O)C(O)C2O)C(N)CC1NC(=N)C(O)=O",-6.382,3,7,5]
["S6446","Sodium citrate dihydrate","d4","L3800-52","in 10mM Water","CFDA, NDC, PMDA","USP43-NF38","N/A","Others","Others","Sodium citrate dehydrate (Trisodium citrate dihydrate, Citric acid trisodium salt dihydrate) is the preferred anticoagulant.",{"v":294.1,"d":"294.10"},"6132-04-3","<1","N/A",{"v":59,"d":"59.00"},200.61,"http://www.selleckchem.com/products/sodium-citrate-dihydrate.html","C6H9Na3O9","Dihydrate","Trisodium citrate dihydrate, Citric acid trisodium salt dihydrate","O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O",-6.156,0,0,5]
["S9794","Melittin","e4","L3800-52","in 10mM Water","FDA, DMF, NDC","N/A","N/A","Phospholipase (e.g. PLA)","Metabolism","Melittin (MLT, Forapin, Forapine) is an activator of phospholipase A2 (PLA2) that stimulates the activity of the low molecular weight PLA2, while it does not the increase the activity of the high molecular weight enzyme.",2846.46,"20449-79-0, 37231-28-0",{"v":-1,"d":"-1.00"},"N/A",{"v":100,"d":"100.00"},35.13,"http://www.selleckchem.com/products/melittin.html","C131H229N39O31","Free Base","MLT, Forapin, Forapine","CCC(C)C(NC(=O)CN)C(=O)NCC(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CO)C(=O)NC(CC2=C[NH]C3=C2C=CC=C3)C(=O)C(=O)C(NC(=O)C(CCCCN)NNC(CCCNC(N)=N)C(=O)NC(CCCCN)C(=O)NC(CCCNC(N)=N)C(=O)NC(CCC(N)=O)C(=O)NC(CCC(N)=O)C(N)=O)C(C)CC",-6.576,28,39,101]
["S9803","Elamipretide (MTP-131)","f4","L3800-52","in 10mM Water","N/A","N/A","Phase 3","Mitochondrial Metabolism,Peroxidases","Metabolism","Elamipretide (MTP-131, SS-31, D-Arg-Dmt-Lys-Phe-NH2) is a cytochrome c peroxidase inhibitor. Elamipretide improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice.",639.79,"736992-21-5",{"v":-1,"d":"-1.00"},"N/A",{"v":100,"d":"100.00"},{"v":156.3,"d":"156.30"},"http://www.selleckchem.com/products/elamipretide-mtp-131.html","C32H49N9O5","Free Base","SS-31, D-Arg-Dmt-Lys-Phe-NH2","CC1=C(CC(NC(=O)C(N)CCCNC(N)=N)C(=O)NC(CCCCN)C(=O)NC(CC2=CC=CC=C2)C(N)=O)C(=CC(=C1)O)C",0.416,4,9,20]
["S5962","DL-Penicillamine","g4","L3800-52","in 10mM Water","FDA, DMF, NDC","N/A","N/A","Others","Others","DL-Penicillamine (DL-beta-Mercaptovaline, 3,3-Dimethyl-DL-cysteine, 3-Sulfanylvaline, Cuprimine, Depen, DL-PenA, DL-P) induces alteration of elastic fibers of periosteum-perichondrium and associates growth inhibition.",149.21,"52-66-4","<1",{"v":0,"d":"0.00"},{"v":30,"d":"30.00"},201.06,"http://www.selleckchem.com/products/dl-penicillamine.html","C5H11NO2S","Free Base","DL-beta-Mercaptovaline, 3,3-Dimethyl-DL-cysteine, 3-Sulfanylvaline, Cuprimine, Depen, DL-PenA","CC(C)(S)C(N)C(O)=O",-2.496,1,1,2]
["S6991","Sodium Acetate","h4","L3800-52","in 10mM Water","FDA, DMF, CFDA, NDC, PMDA","USP–NF 2021(Issue 2), EP10.5, KP Ⅹ, JP17, IP2010","N/A","Others","Others","Sodium acetate is an organic sodium salt. It contains an acetate.",82.03,"127-09-3","<1",{"v":0,"d":"0.00"},{"v":16,"d":"16.00"},195.05,"N/A","CH3COONa","Free Base","N/A","[Na+].CC([O-])=O",-1.679,0,0,0]
["S6992","Calcium chloride","a5","L3800-52","in 10mM Water","FDA, DMF, CFDA, NDC, PMDA","USP–NF 2021(Issue 2), EP10.5, KP Ⅹ, JP17, IP2010","N/A","Others","Others","Calcium chloride is an odorless, white, crystalline solid compound that is highly soluble in water.",110.98,"10043-52-4","<1",{"v":0,"d":"0.00"},{"v":22,"d":"22.00"},198.23,"N/A","CaCl2","Free Base","N/A","[Cl-].[Cl-].[Ca++]",-5.348,0,0,0]
["S7920","L-NMMA acetate","b5","L3800-52","in 10mM Water","N/A","N/A","Phase 4","NOS","Immunology & Inflammation","L-NMMA acetate (Tilarginine Acetate, Methylarginine acetate, NG-Monomethyl-L-arginine acetate,  L-NG-monomethyl Arginine acetate) is an acetate salt form of L-NMMA. L-NMMA is a nitric oxide synthase(NOS) inhibitor with an IC50 of 4.1 μM for nNOS.",248.28,"53308-83-1","<1",{"v":0,"d":"0.00"},{"v":50,"d":"50.00"},201.39,"http://www.selleckchem.com/products/l-nmma-acetate.html","C9H20N4O4","Acetate","Tilarginine Acetate, Methylarginine acetate, NG-Monomethyl-L-arginine acetate,  L-NG-monomethyl Arginine acetate,","CNC(=N)NCCCC(N)C(O)=O.CC(O)=O",-3.829,2,3,7]
["S9489","Sodium citrate","c5","L3800-52","in 10mM Water","FDA, DMF, CFDA, NDC, PMDA","USP–NF 2021(Issue 2), EP10.5, KP Ⅹ, Ph.Int_6th, JP17, IP2010","Marketed","Others","Others","Sodium citrate dehydrate (Trisodium citrate dihydrate, Citric acid trisodium salt dihydrate) is the preferred anticoagulant.",258.07,"68-04-2","<1",{"v":0,"d":"0.00"},{"v":52,"d":"52.00"},{"v":201.5,"d":"201.50"},"N/A","C6H5Na3O7","Free Base","N/A","[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O",-5.741,0,0,5]
["S9820","Angiotensin (1-7)","d5","L3800-52","in 10mM Water","N/A","N/A","Phase 3","ACE,RAAS","Endocrinology & Hormones","Angiotensin (1-7) (Ang-(1-7), Angiotensin fragment 1-7) is a bioactive component of the renin-angiotensin system that is formed endogenously from either Ang I or Ang II. Angiotensin (1-7) is a canine ACE inhibitor with an IC50 of 0.65 μM and inhibits the activity mediated by myostatin through Mas receptor.",{"v":899,"d":"899.00"},"51833-78-4","<1","N/A",{"v":50,"d":"50.00"},55.62,"http://www.selleckchem.com/products/angiotensin-1-7.html","C41H62N12O11","Free Base","Ang-(1-7), Angiotensin fragment 1-7","CCC(C)C(NC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C(NC(=O)C(CCCN=C(N)N)NC(=O)C(N)CC(O)=O)C(C)C)C(=O)NC(CC2=CN=C[NH]2)C(=O)N3CCCC3C(O)=O",{"v":-3.96,"d":"-3.960"},10,10,25]
["E0375","Ammonium ferric citrate","e5","L3800-52","in 10mM Water","CFDA","USP–NF 2021(Issue 2), EP10.5, IP2010","Marketed","Ferroptosis","Apoptosis","Ammonium ferric citrate (Ferric ammonium citrate, Ammonium iron(III) citrate, Iron ammonium citrate, FerriSeltz) induces ferroptosis in non-small-cell lung carcinoma through the inhibition of GPX4-GSS/GSR-GGT axis activity.",978.05,"1185-57-5","<1","N/A",{"v":53,"d":"53.00"},54.19,"http://www.selleckchem.com/products/ammonium-ferric-citrate.html","C24H32Fe3N3O28","Citrate","Ferric ammonium citrate, Ammonium iron(III) citrate, Iron ammonium citrate, FerriSeltz","[NH4+].[NH4+].[NH4+].[Fe+3].[Fe+3].[Fe+3].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O",{"v":-28.54,"d":"-28.540"},0,0,20]
["P1104","Glatiramer acetate","f5","L3800-52","in 10mM Water","FDA, PMDA, NDC","N/A","No development reported","Immunology & Inflammation related","Immunology & Inflammation","Glatiramer acetate is a synthetic copolymer composed of a random mixture of four amino acids that modifies the immune response.",623.65,"147245-92-9","<1","N/A",{"v":100,"d":"100.00"},160.35,"http://www.selleckchem.com/products/glatiramer-acetate.html","C25H45N5O13","Acetate","N/A","CC(N)C(O)=O.CC(O)=O.NCCCCC(N)C(O)=O.NC(CCC(O)=O)C(O)=O.NC(CC1=CC=C(O)C=C1)C(O)=O",{"v":-14.39,"d":"-14.390"},6,6,13]
["S6289","Gentamicin","g5","L3800-52","in 10mM Water","FDA,CFDA,PMDA,NDC","USP28-NF23,JP15","Marketed","Antiviral","Microbiology","Gentamicin, an aminoglycoside class of bactericidal antibiotic, is effective against gram-negative bacterial infections.",1390.71,"1403-66-3","<1","N/A",{"v":100,"d":"100.00"},71.91,"http://www.selleckchem.com/products/gentamicin.html","C60H123N15O21","free base","N/A","CNC(C)C1CCC(N)C(O1)OC2C(N)CC(N)C(OC3OCC(C)(O)C(NC)C3O)C2O.CNC4C(O)C(OCC4(C)O)OC5C(N)CC(N)C(OC6OC(CN)CCC6N)C5O.CNC7C(O)C(OCC7(C)O)OC8C(N)CC(N)C(OC9OC(CCC9N)C(C)N)C8O",-12.679,12,21,19]
["S6872","Merbromin","h5","L3800-52","in 10mM Water","CFDA,PMDA","JP16","Marketed","3C-Like Protease,Bacterial","Proteases","Merbromin (Mercurochrome), a xanthene dye and an antibacterial agent, is the first of a series of antiseptics that contained mercury, also is a mixed-type inhibitor of 3CLpro due to its ability of increasing the KM and decreasing the Kcat of 3CLpro.",752.68,"129-16-8","<1","N/A",{"v":100,"d":"100.00"},132.86,"http://www.selleckchem.com/products/merbromin.html","C20H10Br2HgO6.2Na","free base","Mercurochrome, Merbromine, Mercurocol, Sodium mercurescein, Asceptichrome, Supercrome, Brocasept, Cinfacromin","[NaH].[NaH].O[Hg]C1=C(O)C(=CC2=C1OC3=CC(=C(Br)C=C3C24OC(=O)C5=C4C=CC=C5)O)Br",4.622,3,2,1]
["E0510","Cidofovir hydrate","a6","L3800-52","in 10mM Water","FDA,EMA,NDC,DMF","N/A","Marketed","DNA/RNA Synthesis","DNA Damage/DNA Repair","Cidofovir hydrate is a selective inhibitor of viral DNA synthesis through the selective inhibition of viral DNA polymerase.",315.22,"149394-66-1","<1","N/A",{"v":4,"d":"4.00"},12.69,"http://www.selleckchem.com/products/cidofovir-hydrate.html","C8H14N3O6P.2H2O","Dihydride","N/A","O.O.NC1=NC(=O)N(CC(CO)OC[P;v5](O)(O)=O)C=C1",{"v":-2.59,"d":"-2.590"},3,2,6]
["E0511","Framycetin sulphate","b6","L3800-52","in 10mM Water","HMA,DMF","BP2024;EP11.0;Martindale: The Complete Drug Reference","Marketed","DNA/RNA Synthesis","DNA Damage/DNA Repair","Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM, and competes for specific divalent metal ion binding sites in RNase P RNA, also inhibits hammerhead ribozyme with a Ki of 13.5 μM.",712.72,"4146-30-9","<1","N/A",{"v":100,"d":"100.00"},140.31,"http://www.selleckchem.com/products/framycetin-sulphate.html","C23H48N6O17S","sulphate","N/A","NCC1OC(OC2C(N)CC(N)C(O)C2OC3OC(CO)C(OC4OC(CN)C(O)C(O)C4N)C3O)C(N)C(O)C1O.O[S](O)(=O)=O",-8.832,6,13,9]
["E0525","Colistin","c6","L3800-52","in 10mM Water","FDA,EMA,CFDA,PMDA,HMA,DMF,NDC","N/A","Marketed","Anti-infection","Microbiology","Colistin(Polymyxin E), a cyclic polypeptide antibiotic synthesized by Bacillus polymyxa subspecies colistinus Koyama, exerts antimicrobial activity by targeting at the bacterial cell membrane.",1155.43,"1066-17-7","<1","N/A",{"v":100,"d":"100.00"},86.55,"http://www.selleckchem.com/products/colistimethate.html","C52H98N16O13","free base","Polymyxin E","NA","NA","NA","NA","NA"]
["E0532","Menotropin","d6","L3800-52","in 10mM Water","DMF","JP18","Marketed","Estrogen/progestogen Receptor","Endocrinology & Hormones","Menotropin (Human Menopausal Gonadotrophin) is a hormonally active medication for the treatment of fertility disturbances, which are extracted from the urine of postmenopausal women.",142.24,"61489-71-2","<1","N/A",{"v":28,"d":"28.00"},196.85,"http://www.selleckchem.com/products/menotropin.html","C9H18O","free base","Human Menopausal Gonadotrophin","CC(C)(C)CCCCC=O",2.767,1,0,5]
["E0705","Flavin Adenine Dinucleotide Disodium","e6","L3800-52","in 10mM Water","PMDA","JP18","Marketed","Others","Metabolism","Flavin Adenine Dinucleotide Disodium is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.",831.53,"84366-81-4","<1","N/A",{"v":100,"d":"100.00"},120.26,"http://www.selleckchem.com/products/flavin-adenine-dinucleotide-disodium.html","C27H33N9O15P2.2Na","disodium salt","N/A","[NaH].[NaH].CC1=C(C)C=C2N(CC(O)C(O)C(O)CO[P;v5](O)(=O)O[P;v5](O)(=O)OCC3OC(C(O)C3O)[N]4C=NC5=C(N)N=CN=C45)C6=NC(=O)NC(=O)C6=NC2=C1",-2.097,11,7,13]
["E2635","Bicinchoninic acid disodium salt","f6","L3800-52","in 10mM Water","N/A","N/A","Phase I/II","Others","Others","Bicinchoninic acid disodium salt is used for determination of reducing sugar and protein though Copper.",{"v":390.3,"d":"390.30"},"979-88-4","<1","N/A",{"v":39,"d":"39.00"},99.92,"http://www.selleckchem.com/products/bicinchoninic-acid-disodium-salt.html","C20H12N2O4.2Na","disodium salt","N/A","[NaH].[NaH].OC(=O)C1=CC(=NC2=C1C=CC=C2)C3=NC4=C(C=CC=C4)C(=C3)C(O)=O",3.837,4,0,3]
["E2638","Tricine","g6","L3800-52","in 10mM Water","N/A","EP10.8,IP2010","N/A","Others","Others","Tricine (N-[Tris(hydroxymethyl)methyl]glycine) is a buffer component for separation of low molecular weight peptides.",179.17,"5704-04-1","<1","N/A",{"v":36,"d":"36.00"},200.93,"http://www.selleckchem.com/products/tricine.html","C6H13NO5","free base","N-[Tris(hydroxymethyl)methyl]glycine","OCC(CO)(CO)NCC(O)=O",-5.173,1,4,6]
["E2830","Cyclocreatine","h6","L3800-52","in 10mM Water","N/A","N/A","Phase 1","Others","Others","Cyclocreatine is a Creatine analogue and acts as a potent bioenergetic protective agent by preserving high levels of ATP.",143.14,"35404-50-3","<1","N/A",{"v":7,"d":"7.00"},{"v":48.9,"d":"48.90"},"http://www.selleckchem.com/products/cyclocreatine.html","C5H9N3O2","free base","N/A","NC1=NCCN1CC(O)=O",{"v":-1.07,"d":"-1.070"},2,1,2]
["S3736","Fondaparinux Sodium (Org 31540)","a7","L3800-52","in 10mM Water","FDA,EMA,HMA,CFDA,PMDA,NDC,DMF","N/A","Marketed","Factor Xa","Metabolism","Fondaparinux Sodium (Org 31540, Natural heparin pentasaccharide, Fondaparin, SR-90107A) is a synthetic glucopyranoside with antithrombotic activity. It selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin; a synthetic inhibitor of Factor Xa.",1728.08,"114870-03-0",{"v":1,"d":"1.00"},0.58,{"v":100,"d":"100.00"},57.87,"http://www.selleckchem.com/products/fondaparinux-sodium.html","C31H43N3O49S8.10Na","Sodium salt","Natural heparin pentasaccharide Sodium, Fondaparin sodium, SR-90107A","[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].COC1OC(CO[S]([O-])(=O)=O)C(OC2OC(C(OC3OC(CO[S]([O-])(=O)=O)C(OC4OC(C(OC5OC(CO[S]([O-])(=O)=O)C(O)C(O)C5N[S]([O-])(=O)=O)C(O)C4O)C([O-])=O)C(O[S]([O-])(=O)=O)C3N[S]([O-])(=O)=O)C(O)C2O[S]([O-])(=O)=O)C([O-])=O)C(O)C1N[S]([O-])(=O)=O",-32.806,15,9,30]
["S8505","LY2510924","c7","L3800-52","in 10mM Water","N/A","N/A","Phase II","CXCR","Immunology & Inflammation","LY2510924 is a potent and selective CXCR4 antagonist that specifically blocks SDF-1 binding to CXCR4 with IC50 value of 0.079 nmol/L and inhibits SDF-1-induced GTP binding with Kb value of 0.38 nmol/L.",1189.45,"1088715-84-7","<1","N/A",{"v":100,"d":"100.00"},84.07,"http://www.selleckchem.com/products/ly2510924.html","C62H88N14O10","Free base","N/A","CC(C)NCCCCC(NC(=O)C1CCC(=O)NC(CC2=CC=CC=C2)C(=O)NC(CC3=CC=C(O)C=C3)C(=O)NC(CCCCNC(C)C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC4=CC5=C(C=CC=C5)C=C4)C(=O)NCC(=O)N1)C(N)=O",1.764,9,14,26]
["S9725","Balixafortide (POL6326)","d7","L3800-52","in 10mM Water","N/A","N/A","Phase III","CXCR","Immunology & Inflammation","Balixafortide (POL6326) is an orally bioavailable peptidic CXC chemokine receptor 4 (CXCR4) antagonist.",1864.11,"1051366-32-5","<1","N/A",{"v":100,"d":"100.00"},53.64,"http://www.selleckchem.com/products/balixafortide-pol6326.html","C84H118N24O21S2","Free base","N/A","CC1NNC(CC2=CN=C[NH]2)C(=O)NC(CC3=CC=C(O)C=C3)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)NC(CCCCN)C(=O)NC(CCC(N)=O)C(=O)NC(CC6=CC=C(O)C=C6)C(=O)NC7CSSCC(NC1=O)C(=O)NC(CO)C(=O)NC(C)C(=O)N8CCCC8C(=O)NC(CCN)C(=O)NC(CCCNC(N)=N)C(=O)C(=O)C(CC9=CC=C(O)C=C9)NC7=O",-6.059,18,23,23]
["E1223","RGX-202","e7","L3800-52","in 10mM Water","N/A","N/A","Phase 2","Apoptosis related","Metabolism","RGX-202 is an SLC6A8 transporter inhibitor which suppress the colon cancer tumor. In addition to significantly reducing intracellular phosphocreatine and ATP levels and inducing tumour apoptosis, RGX-202 also inhibits creatine import both in vitro and in vivo.",131.13,"353-09-3","<1","N/A",{"v":26,"d":"26.00"},198.28,"https://www.selleckchem.com/products/rgx-202.html","C4H9N3O2","Free base","N/A","NC(=N)NCCC(O)=O",-1.052,1,2,4]
["E2035","Larazotide","f7","L3800-52","in 10mM Water","N/A","N/A","Phase III","Others","Others","Larazotide(AT-1001) is an antagonist of Zonulin, which appears safe and well-tolerated and may offer potential benefit as an adjuvant to immune-targeted therapies.",725.83,"258818-34-7","<1","N/A",{"v":25,"d":"25.00"},34.44,"http://www.selleckchem.com/products/larazotide.html","C32H55N9O10","Free base","AT-1001","CC(C)CC(NC(=O)C(NC(=O)CNC(=O)CN)C(C)C)C(=O)NC(C(C)C)C(=O)NC(CCC(N)=O)C(=O)N1CCCC1C(=O)NCC(O)=O",-5.496,9,8,21]
["P1019","Cetrorelix Acetate","g7","L3800-52","in 10mM Water","FDA,EMA,CFDA,PMDA,DMF","N/A","Marketed","GNRH Receptor","Endocrinology & Hormones","Cetrorelix Acetate (NS 75A Acetate, SB 075 Acetate, SB 75 Acetate) is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH) with an IC50 of 1.21 nM.",1551.14,"130143-01-0","<1","N/A",{"v":100,"d":"100.00"},64.47,"http://www.selleckchem.com/peptide/cetrorelix-acetate.html","C70H92ClN17O14.2(C2H4O2)","Acetate","Ac-3-(2-naphthyl)-D-Ala-4-Chloro-D-Phe-3(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2","CC(C)CC(NC(=O)C(CCCNC(N)=O)NC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C(CO)NC(=O)C(CC2=CN=CC=C2)NC(=O)C(CC3=CC=C(Cl)C=C3)NC(=O)C(CC4=CC5=CC=CC=C5C=C4)NC(C)=O)C(=O)NC(CCCN=C(N)N)C(=O)N6CCCC6C(=O)NC(C)C(N)=O.CC(O)=O.CC(O)=O",{"v":-0.13,"d":"-0.130"},16,16,38]
["P1027","Melanotan II","h7","L3800-52","in 10mM Water","N/A","N/A","Phase II","5-alpha Reductase","Angiogenesis","Melanotan II is an analog of the peptide hormone alpha-melanocyte stimulating hormone (α-MSH).",{"v":1084.2,"d":"1084.20"},"121062-08-6","<1","N/A",{"v":100,"d":"100.00"},92.23,"http://www.selleckchem.com/peptide/Melanotan-II(Melanotan-2).html","C52H73N15O11","Free base","MT-II","CCCCC(NC(C)=O)C(=O)NC1CC(=O)NCCCCC(NC(=O)C(CC2=C[NH]C3=CC=CC=C23)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CN=C[NH]5)NC1=O)C(N)=O",-0.877,10,13,18]
["E0149","Papain","a8","L3800-52","in 10mM Water","CFDA","USP–NF 2021(Issue 2), EP10.5, IP2010","N/A","Others","Others","Papain (papaya proteinase I) is a sulfhydryl protease from the latex of the papaya fruit. Papain breaks down intercellular matrix of cartilage.",226.23,"9001-73-4","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://www.selleckchem.com/products/papain.html","C9H14N4O3","Free Base","papaya proteinase I","NCCC(=O)NC(CC1=CN=C[NH]1)C(O)=O",{"v":-4.41,"d":"-4.410"},3,3,6]
["S6482","Fosphenytoin (disodium)","b8","L3800-52","in 10mM Water","FDA,DMF,NDC,PMDA","Martindale the Extra Pharmacopoei,USP39-NF34","Marketed","Others","Others","Fosphenytoin (disodium) is the sodium salt form of fosphenytoin, a prodrug that is hydrolyzed to the anticonvulsant phenytoin upon parental administration.",406.24,"92134-98-0","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://www.selleck.cn/products/fosphenytoin.html","C16H13N2Na2O6P","disodium","N/A","[Na+].[Na+].[O-][P]([O-])(=O)OCN1C(=O)NC(C1=O)(C2=CC=CC=C2)C3=CC=CC=C3",-0.495,3,1,5]
["S5961","Prednisolone disodium phosphate","c8","L3800-52","in 10mM Water","FDA,CFDA,PMDA,NDC,DMF","USP40-NF35,IP2010,JP16","Marketed","Anti-infection","Microbiology","Prednisolone disodium phosphate (Hydeltrasol, Prednisolone 21-phosphate disodium) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties that exerts late mitogenic and biphasic effects on resistant acute lymphoblastic leukemia cells.",484.39,"125-02-0","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://www.selleckchem.com/products/prednisolone-disodium-phosphate.html","C21H27Na2O8P","Phosphate","Hydeltrasol, Prednisolone 21-phosphate disodium","[Na+].[Na+].CC12CC(O)C3C(CCC4=CC(=O)C=CC34C)C1CCC2(O)C(=O)CO[P]([O-])([O-])=O",-0.989,3,1,4]
["E0178","Cysteamine bitartrate","d8","L3800-52","in 10mM Water","FDA,EMA,PMDA,DMF","N/A","Marketed","Others","Others","Cysteamine bitartrate (Mercaptamine bitartrate) is an FDA-approved cystine-depleting aminothiol agent for the treatment of nephropathic cystinosis to decrease accumulation of lysosomal cystine by engaging in disulfide exchange. In addition, cysteamine bitartrate has antioxidant properties.",227.24,"27761-19-9","N/A","N/A","N/A",{"v":10,"d":"10.00"},"http://www.selleckchem.com/products/cysteamine-bitartrate.html","C6H13NO6S","Bitartrate","Mercaptamine bitartrate","NCCS.OC(C(O)C(O)=O)C(O)=O",-4.359,2,3,4]
["E4227","D-Cysteine","e8","L3800-52","in 10mM Water","FDA","N/A","Marketed","Antibacterial; Endogenous Metabolite","Metabolism; Microbiology/virology","D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of the growth of E. coli. D-cysteine is mediated by D-amino acid oxidase to produce H2S, and is a neuroprotective agent against cerebellar ataxia. D-cysteine can inhibit the growth and cariogenicity of a two-species biofilm formed by Streptococcus mutans and Streptococcus hemoglobin.",121.16,"921-01-7","N/A","N/A","N/A",">10","https://www.selleckchem.com/products/d-cysteine.html","C3H7NO2S","free base","D-Cysteine","NC(CS)C(O)=O",-3.078,1,1,2]
["E4258","L-Norleucine","f8","L3800-52","in 10mM Water","N/A","N/A","Phase 2","Endogenous Metabolite","Metabolism","L-Norleucine is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.",131.17,"327-57-1","N/A","N/A","N/A",">10","https://www.selleckchem.com/products/l-norleucine.html","C6H13NO2","free base","L-Norleucine","CCCCC(N)C(O)=O",-1.725,1,1,4]
["E4111","Phytic acid (dodecasodium salt hydrate)","g8","L3800-52","in 10mM Water","N/A","N/A","Phase 3","Xanthine Oxidase","Metabolism","Phytic acid (dodecasodium salt hydrate) is a phosphorus storage compound of seeds and cereal grains. It is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue and inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.",957.87,"123408-98-0","N/A","N/A","N/A",">10","https://www.selleckchem.com/products/phytic-acid-dodecasodium-salt-hydrate.html","C6H6O24P6.H2O.12Na","dodecasodium salt","Inositol hexaphosphate dodecasodium hydrate","O.[Na;v0].O[P](O)(=O)OC1C(O[P](O)(O)=O)C(O[P](O)(O)=O)C(O[P](O)(O)=O)C(O[P](O)(O)=O)C1O[P](O)(O)=O",-3.701,6,0,12]
["E2759","L-(+)-Ergothioneine","h8","L3800-52","in 10mM Water","N/A","N/A","Phase 3","Others","Others","L-(+)-Ergothioneine(Ergothioneine), an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant.",{"v":229.3,"d":"229.30"},"497-30-3","<1","N/A",{"v":46,"d":"46.00"},200.61,"https://www.selleckchem.com/products/l--ergothioneine.html","C9H15N3O2S","Free base","Ergothioneine","C[N+](C)(C)C(CC1=CNC(=S)N1)C([O-])=O",-2.967,0,2,4]
["E4002","Potassium D-gluconate","a9","L3800-52","in 10mM Water","PMDA,DMF,NDC","USP-NF2024;Martindale: The Complete Drug Reference","Marketed","Fungal","Microbiology","Potassium D-gluconate(Potassium Gluconate) is an orally active carboxylic acid by the oxidation with antiseptic and chelating properties.",235.25,"299-27-4",{"v":2,"d":"2.00"},{"v":8.5,"d":"8.50"},{"v":47,"d":"47.00"},199.79,"https://www.selleckchem.com/products/potassium-d-gluconate.html","C6H12O7.K","Potassium","Potassium Gluconate","[K;v0].OCC(O)C(O)C(O)C(O)C(O)=O",-2.813,1,5,5]
["E4018","Ammonium sulfate","b9","L3800-52","in 10mM Water","NDC;FDA","N/A","marketed","Others","Others","Ammonium sulphate (Mascagnite) is an inorganic sulfate salt used for the purification of enzymes and antibodies.",132.14,"7783-20-2","<1","N/A",{"v":23,"d":"23.00"},174.06,"https://www.selleckchem.com/products/ammonium-sulfate.html","H3N.1/2H2O4S","Ammonium","Mascagnite","N.O[S](O)(=O)=O",-0.918,0,0,0]
["E2895","Sodium Bicarbonate","c9","L3800-52","in 10mM Water","FDA;NDC;PMDA;HMA;DMF","N/A","Phase 2","Others","Others","Sodium bicarbonate(Armex Blast Media Flow Formula XL, BI-CF 40E, BI-H 40E, Bakeshure 180, Sodium Hydrogen Carbonate, Sodium hydrogen carbonate) is a biochemical reagent used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.",85.01,"144-55-8","<1","N/A",{"v":25,"d":"25.00"},294.08,"https://www.selleckchem.com/products/sodium-bicarbonate.html","CH2O3.Na","Free base","Armex Blast Media Flow Formula XL, BI-CF 40E, BI-H 40E, Bakeshure 180, Sodium Hydrogen Carbonate, Sodium hydrogen carbonate","[Na;v0].OC(O)=O",0.213,0,0,0]
["E4470","Potassium Chloride","d9","L3800-52","in 10mM Water","DMF; FDA; NDC; NMPA","N/A","marketed","Others","Others","Potassium chloride is an inorganic salt commonly used in fertilizer industry. It is also extensively used as a potassium supplement.",74.55,"7447-40-7","<1","N/A",{"v":100,"d":"100.00"},1341.38,"https://www.selleckchem.com/products/potassium-chloride.html","ClK","Potassium","N/A","Cl[K]",0.485,0,0,0]
["E4578","Trilaciclib dihydrochloride","e9","L3800-52","in 10mM Water","FDA,NDC,DMF","N/A","Marketed","CDK","Cell Cycle","Trilaciclib dihydrochloride(G1T28 dihydrochloride) is a potent inhibitor of <b>CDK4/cyclin D1</b> and <b>CDK6/cyclin D3</b> with IC50s of 1 nM and 4 nM for CDK4 and CDK6, respectively. Trilaciclib hydrochloride regulates cell proliferation and protects against chemotherapy toxicity in murine and canine bone marrow cells.",519.47,"1977495-97-8",{"v":1.3,"d":"1.30"},{"v":2.5,"d":"2.50"},{"v":25,"d":"25.00"},48.13,"https://www.selleckchem.com/products/trilaciclib-hydrochloride.html","C24H30N8O.2ClH","dihydrochloride","G1T28 dihydrochloride","[ClH:34].[CH3:3][N:33]1[CH2:31][CH2:29][N:28]([CH2:30][CH2:32]1)[C:27]2=[CH:25][CH:23]=[C:22]([NH:2][C:20]3=[N:21][CH:19]=[C:14]4[CH:16]=[C:10]5[N:5]([C:9]4=[N:15]3)[C:4]6([CH2:7][CH2:12][CH2:18][CH2:13][CH2:8]6)[CH2:6][NH:11][C:17]5=[O:1])[N:24]=[CH:26]2",3.743,4,{"v":2,"d":"2.000"},3]
["S2542","Phenformin (NSC-756501) HCl","f9","L3800-52","in 10mM Water","DMF","Martindale:The Extra Pharmacopoeia","N/A","AMPK","PI3K/Akt/mTOR","Phenformin HCl (NSC-756501, Phenethylbiguanide) is a hydrochloride salt of phenformin that is an anti-diabetic drug from the biguanide class. It activates AMPK, increasing activity and phosphorylation.",241.72,"834-28-6","N/A","N/A","N/A",">10","http://selleckchem.com/products/Phenformin-hydrochloride.html","C10H15N5.HCl","Hydrochloride","Phenethylbiguanide HCl","Cl.NC(=N)NC(=N)NCCC1=CC=CC=C1",1.339,0,3,6]
["S1019","Canertinib (CI-1033)","a2","L3800-53","in 2mM DMSO","N/A","N/A","Phase 2","EGFR,HER2","Protein Tyrosine Kinase","Canertinib (CI-1033, PD183805) is a pan-ErbB inhibitor for EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, no activity to PDGFR, FGFR, InsR, PKC, or CDK1/2/4. Phase 3.",485.94,"267243-28-7",{"v":2,"d":"2.00"},4.12,"<1","N/A","http://selleckchem.com/products/CI-1033(Canertinib).html","C24H25ClFN5O3","Free Base","PD183805","FC1=C(Cl)C=C(NC2=NC=NC3=CC(=C(NC(=O)C=C)C=C23)OCCCN4CCOCC4)C=C1",4.037,5,2,9]
["S1023","Erlotinib (OSI-774) HCl","b2","L3800-53","in 2mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Autophagy,EGFR","Protein Tyrosine Kinase","Erlotinib (OSI-774, CP358774, NSC 718781) HCl is an EGFR inhibitor with IC50 of 2 nM in cell-free assays, >1000-fold more sensitive for EGFR than human c-Src or v-Abl.",{"v":429.9,"d":"429.90"},"183319-69-9",{"v":4,"d":"4.00"},{"v":9.3,"d":"9.30"},"<1","N/A","http://selleckchem.com/products/Erlotinib-Hydrochloride.html","C22H23N3O4.HCl","Hydrochloride","CP358774, NSC 718781,OSI-774 HCl","Cl.COCCOC1=C(OCCOC)C=C2C(=NC=NC2=C1)NC3=CC=CC(=C3)C#C",4.691,6,1,10]
["S1043","Tandutinib (MLN518)","c2","L3800-53","in 2mM DMSO","N/A","N/A","Phase 2","FLT3","Angiogenesis","Tandutinib (MLN518, CT53518, NSC726292) is a potent FLT3 antagonist with IC50 of 0.22 μM, also inhibits PDGFR and c-Kit, 15 to 20-fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR and KDR. Phase 2.",{"v":562.7,"d":"562.70"},"387867-13-2",{"v":5,"d":"5.00"},8.89,"<1","N/A","http://selleckchem.com/products/Tandutinib-(MLN518).html","C31H42N6O4","Free Base","CT 53518, NSC726292, MLN518","COC1=CC2=C(C=C1OCCCN3CCCCC3)N=CN=C2N4CCN(CC4)C(=O)NC5=CC=C(OC(C)C)C=C5",4.674,6,1,10]
["S1046","Vandetanib (ZD6474)","d2","L3800-53","in 2mM DMSO","FDA,EMA,NDC,PMDA","N/A","Marketed","Apoptosis related,Autophagy,EGFR,ROS,VEGFR","Protein Tyrosine Kinase","Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 with IC50 of 40 nM in a cell-free assay. It also inhibits VEGFR3 and EGFR with IC50 of 110 nM and 500 nM, respectively. Not sensitive to PDGFRβ, Flt1, Tie-2 and FGFR1 with IC50 of 1.1-3.6 μM. No activity against MEK, CDK2, c-Kit, erbB2, FAK, PDK1, Akt and IGF-1R with IC50 above 10 μM. Vandetanib (ZD6474) increases apoptosis and induces autophagy by increasing the level of reactive oxygen species (ROS).",475.35,"443913-73-3",{"v":4,"d":"4.00"},8.41,"<1","N/A","http://selleckchem.com/products/Vandetanib.html","C22H24BrFN4O2","free base","ZD6474","COC1=CC2=C(C=C1OCC3CCN(C)CC3)N=CN=C2NC4=C(F)C=C(Br)C=C4",5.087,4,1,6]
["S1112","SGX-523","e2","L3800-53","in 2mM DMSO","N/A","N/A","Phase 1","c-Met","Protein Tyrosine Kinase","SGX-523 is a selective Met (c-Met) inhibitor with IC50 of 4 nM, no activity to BRAFV599E, c-Raf, Abl and p38α. Phase 1.",359.41,"1022150-57-7",{"v":3,"d":"3.00"},8.35,"<1","N/A","http://selleckchem.com/products/SGX-523.html","C18H13N7S","free base","N/A","C[N]1C=C(C=N1)C2=N[N]3C(=NN=C3C=C2)SC4=CC=C5N=CC=CC5=C4",{"v":3.58,"d":"3.580"},5,0,3]
["S1211","Imiquimod (R-837)","f2","L3800-53","in 2mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","Marketed","Immunology & Inflammation related","Immunology & Inflammation","Imiquimod (Aldara,R-837,S-26308) is a novel synthetic agent with immune response modifying activity.",{"v":240.3,"d":"240.30"},"99011-02-6",{"v":1,"d":"1.00"},4.16,"<1","N/A","http://selleckchem.com/products/Imiquimod.html","C14H16N4","free base","Aldara,R-837, S-26308","CC(C)C[N]1C=NC2=C(N)N=C3C=CC=CC3=C12",2.722,2,1,2]
["S1288","Camptothecin (NSC-100880)","g2","L3800-53","in 2mM DMSO","DMF,CFDA","N/A","Phase 2","ADC Cytotoxin,Apoptosis related,MicroRNA,Topoisomerase","DNA Damage/DNA Repair","Camptothecin (NSC-100880, CPT, Campathecin, (S)-(+)-Camptothecin) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM in a cell-free assay. Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2.",348.35,"7689-03-4",{"v":3,"d":"3.00"},8.61,"<1","N/A","http://selleckchem.com/products/Camptothecine.html","C20H16N2O4","Free Base","CPT, Campathecin, (S)-(+)-Camptothecin","CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC=CC5=C4)C2=O",1.746,4,0,1]
["S1327","Ellagic acid","h2","L3800-53","in 2mM DMSO","N/A","N/A","Phase 2","Topoisomerase","DNA Damage/DNA Repair","Ellagic acid (Elagostasine, Gallogen) has antiproliferative and antioxidant property.",302.19,"476-66-4",{"v":3,"d":"3.00"},9.93,"<1","N/A","http://selleckchem.com/products/Ellagic-acid.html","C14H6O8","free base","Elagostasine, Gallogen","OC1=CC2=C3C(=C1O)OC(=O)C4=CC(=C(O)C(=C34)OC2=O)O",{"v":0,"d":"0.000"},0,0,0]
["S1353","Ketoconazole (R 41400)","a3","L3800-53","in 2mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,KP Ⅹ,EP9.2,Ph.Int_6th,JP17,BP2017,IP2010","Marketed","Androgen Receptor,Fungal,P450 (e.g. CYP17)","Metabolism","Ketoconazole (R 41400) inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively. Ketoconazole is an androgen biosynthesis inhibitor.",531.43,"65277-42-1",{"v":5,"d":"5.00"},9.41,"<1","N/A","http://selleckchem.com/products/Ketoconazole.html","C26H28Cl2N4O4","free base","R 41400","CC(=O)N1CCN(CC1)C2=CC=C(OCC3COC(C[N]4C=CN=C4)(O3)C5=CC=C(Cl)C=C5Cl)C=C2",{"v":3.61,"d":"3.610"},5,0,7]
["S1360","GSK1059615","b3","L3800-53","in 2mM DMSO","N/A","N/A","Phase 1","mTOR,PI3K","PI3K/Akt/mTOR","GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively. Phase 1.",333.36,"958852-01-2",{"v":2,"d":"2.00"},{"v":6,"d":"6.00"},"<1","N/A","http://selleckchem.com/products/GSK1059615.html","C18H11N3O2S","Free Base","N/A","O=C1NC(=O)/C(S1)=C/C2=CC=C3N=CC=C(C4=CC=NC=C4)C3=C2",2.496,4,1,2]
["S1371","Cefoselis Sulfate","c3","L3800-53","in 2mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics","Microbiology","Cefoselis (FK 037 Sulfate) is a widely used beta-lactam antibiotic.",620.64,"122841-12-7",{"v":3,"d":"3.00"},4.83,{"v":5,"d":"5.00"},8.06,"http://selleckchem.com/products/Cefoselis-sulfate.html","C19H22N8O6S2.H2SO4","Sulfate","FK 037 Sulfate","CO/N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(O)=O)CN3C=CC(=N)N3CCO)C4=CSC(=N4)N.O[S](O)(=O)=O",-2.894,6,3,9]
["S1424","Prazosin HCl","d3","L3800-53","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.8,JP17,BP2017,IP2010","N/A","Adrenergic Receptor","GPCR & G Protein","Prazosin HCl (cp-12299-1) is a competitive alpha-1 adrenoceptor antagonist, used to treat high blood pressure or benign prostatic hyperplasia.",419.86,"19237-84-4",{"v":4,"d":"4.00"},9.53,"<1","N/A","http://selleckchem.com/products/Prazosin-hydrochloride.html","C19H21N5O4.HCl","Hydrochloride","cp-12299-1","Cl.COC1=CC2=C(C=C1OC)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N",2.489,6,1,4]
["S1463","Ofloxacin","e3","L3800-53","in 2mM DMSO","FDA,CFDA,DMF,PMDA","Martindale the Extra Pharmacopoei,CP2005,EP9.2,JP17,BP2017,USP39-NF34,IP2010","N/A","Topoisomerase","DNA Damage/DNA Repair","Ofloxacin (DL8280) is a synthetic broad-spectrum antimicrobial agent.",361.37,"82419-36-1",{"v":1,"d":"1.00"},2.77,"<1","N/A","http://www.selleck.cn/products/Ofloxacin(Floxin).html","C18H20FN3O4","Free Base","DL8280","CC1COC2=C(N3CCN(C)CC3)C(=CC4=C2N1C=C(C(O)=O)C4=O)F",-1.374,3,0,2]
["S1464","Marbofloxacin","f3","L3800-53","in 2mM DMSO","N/A","USP42-NF37;BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Topoisomerase","DNA Damage/DNA Repair","Marbofloxacin is a potent antibiotic inhibiting bacterial DNA replication.",362.36,"115550-35-1",{"v":3,"d":"3.00"},8.28,"<1","N/A","http://selleckchem.com/products/Marbofloxacin.html","C17H19FN4O4","free base","N/A","CN1CCN(CC1)C2=C(F)C=C3C(=O)C(=CN4N(C)COC2=C34)C(O)=O",-2.038,3,0,2]
["S1507","Irbesartan","g3","L3800-53","in 2mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,JP17,BP2017","Marketed","Angiotensin Receptor","GPCR & G Protein","Irbesartan (BMS-186295, SR-47436,APROVEL) is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM.",428.53,"138402-11-6",{"v":4,"d":"4.00"},9.33,"<1","N/A","http://selleckchem.com/products/Irbesartan(Avapro).html","C25H28N6O","free base","BMS-186295, SR-47436,APROVEL","CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=N[NH]N=N5",{"v":0,"d":"0.000"},0,0,0]
["S1509","Norfloxacin","h3","L3800-53","in 2mM DMSO","FDA,DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.3,KP Ⅹ,JP17,BP2017,IP2010","N/A","Topoisomerase","DNA Damage/DNA Repair","Norfloxacin (MK-0366) is a broad-spectrum antibiotic. Norfloxacin (MK-0366) targets bacterial gyrase and topoisomerase IV enzymes.",319.33,"70458-96-7",{"v":3,"d":"3.00"},9.39,"<1","N/A","http://selleckchem.com/products/Norfloxacin(Norxacin).html","C16H18FN3O3","free base","MK-0366","CCN1C=C(C(O)=O)C(=O)C2=CC(=C(C=C12)N3CCNCC3)F",{"v":0,"d":"0.000"},0,0,0]
["S1615","Risperidone","a4","L3800-53","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,JP17,BP2017","Marketed","5-HT Receptor","Neuronal Signaling","Risperidone (R-64766) is a mutil-targeted antagonist for dopamine, serotonin, adrenergic and histamine receptors, used to treat schizophrenia and bipolar disorder.",410.48,"106266-06-2",{"v":4,"d":"4.00"},9.74,"<1","N/A","http://selleckchem.com/products/Risperidone(Risperdal).html","C23H27FN4O2","free base","R-64766","CC1=C(CCN2CCC(CC2)C3=NOC4=C3C=CC(=C4)F)C(=O)N5CCCCC5=N1",3.317,4,0,4]
["S1617","Sulfapyridine","b4","L3800-53","in 2mM DMSO","FDA,DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37","N/A","Bacterial","Microbiology","Sulfapyridine  is a sulfonamide antibacterial.",249.29,"144-83-2",{"v":2,"d":"2.00"},8.02,"<1","N/A","http://selleckchem.com/products/Sulfapyridine(Dagenan).html","C11H11N3O2S","free base","N/A","NC1=CC=C(C=C1)[S](=O)(=O)NC2=NC=CC=C2",0.959,3,2,3]
["S1642","Methyldopa","c4","L3800-53","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,Ph.Int_6th,JP17,BP2017,IP2010","N/A","5-HT Receptor,Adrenergic Receptor,Decarboxylase,Dopamine Receptor","Metabolism","Methyldopa (Aldomet) is a DOPA decarboxylase competitive inhibitor with an ED50 of 21.8 mg/kg.",211.21,"555-30-6",{"v":2,"d":"2.00"},9.47,"<1","N/A","http://selleckchem.com/products/Methyldopa(Aldomet).html","C10H13NO4","free base","N/A","CC(N)(CC1=CC(=C(O)C=C1)O)C(O)=O",{"v":0,"d":"0.000"},0,0,0]
["S1698","Torsemide","d4","L3800-53","in 2mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37,KP Ⅹ","Marketed","Chloride Channel","Transmembrane Transporters","Torsemide (AC-4464, JDL-464) is a pyridyl sulfonylurea with a chemical structure between that of traditional loop diuretics and Cl- channel blockers, used to treat hypertension.",348.42,"56211-40-6",{"v":3,"d":"3.00"},8.61,"<1","N/A","http://selleckchem.com/products/Torsemide(Demadex).html","C16H20N4O3S","free base","AC-4464, JDL-464","CC(C)NC(=O)N[S](=O)(=O)C1=C(NC2=CC(=CC=C2)C)C=CN=C1",{"v":0,"d":"0.000"},0,0,0]
["S1707","Eplerenone (CGP 30083)","e4","L3800-53","in 2mM DMSO","FDA,DMF,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.2,JP17,BP2017","Marketed","Mineralocorticoid Receptor","Endocrinology & Hormones","Eplerenone (CGP 30083, SC-66110) is a mineralocorticoid receptor antagonist, and blocks the action of aldosterone, used to control high blood pressure.",414.49,"107724-20-9",{"v":4,"d":"4.00"},9.65,"<1","N/A","http://selleckchem.com/products/Eplerenone(Inspra).html","C24H30O6","free base","CGP 30083, SC-66110","COC(=O)C1CC2=CC(=O)CCC2(C)C34OC3CC5(C)C(CCC56CCC(=O)O6)C14",{"v":0,"d":"0.000"},0,0,0]
["S1724","Paliperidone","f4","L3800-53","in 2mM DMSO","FDA,DMF,EMA,HMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37","Marketed","Dopamine Receptor","Neuronal Signaling","Paliperidone, the main active metabolite of Risperidone, is a potent serotonin-2A and dopamine-2 receptor antagonist, used in the treatment of schizophrenia.",426.48,"144598-75-4",{"v":4,"d":"4.00"},9.38,"<1","N/A","http://selleckchem.com/products/Paliperidone(Invega).html","C23H27FN4O3","free base","N/A","CC1=C(CCN2CCC(CC2)C3=NOC4=C3C=CC(=C4)F)C(=O)N5CCCC(O)C5=N1",{"v":0,"d":"0.000"},0,0,0]
["S1837","Flubendazole","g4","L3800-53","in 2mM DMSO","N/A","BP2019;KP Ⅹ;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Autophagy,Parasite","Autophagy","Flubendazole (Flumoxanal, NSC 313680) is an autophagy inducer by targeting Atg4B, used to treat internal parasite and worm infection.",313.28,"31430-15-6",{"v":3,"d":"3.00"},9.58,"<1","N/A","http://selleckchem.com/products/flubendazole-flutelmium.html","C16H12FN3O3","free base","Flumoxanal, NSC 313680","COC(=O)NC1=NC2=C([NH]1)C=C(C=C2)C(=O)C3=CC=C(F)C=C3",{"v":3.26,"d":"3.260"},4,2,4]
["S1851","Oxibendazole","h4","L3800-53","in 2mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Parasite","Microbiology","Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets.",249.27,"20559-55-1",{"v":1,"d":"1.00"},4.01,"<1","N/A","http://selleckchem.com/products/oxibendazole.html","C12H15N3O3","Free Base","N/A","CCCOC1=CC=C2N=C(NC(=O)OC)[NH]C2=C1",2.506,4,2,5]
["S1929","Irsogladine","a5","L3800-53","in 2mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17","N/A","AChR,PDE","Metabolism","Irsogladine(Dicloguamine) is an anti-gastric ulcer agent that facilitates gap-junctional intercellular communication through M1 muscarininc acetylcholine receptor binding.",256.09,"57381-26-7",{"v":2,"d":"2.00"},7.81,"<1","N/A","http://selleckchem.com/products/Irsogladine-maleate.html","C9H7Cl2N5","free base","Dicloguamine","NC1=NC(=NC(=N1)C2=C(Cl)C=CC(=C2)Cl)N",2.443,3,2,1]
["S1977","Sarafloxacin HCl","b5","L3800-53","in 2mM DMSO","N/A","BP2019;EP9.2;Martindale:The Extra Pharmacopoeia","N/A","Antibiotics","Microbiology","Sarafloxacin HCl (A-56620) is a hydrochloride salt form of sarafloxacin which is a quinolone antibiotic drug with IC50 of 0.96 μg/L.",421.83,"91296-87-6",{"v":4,"d":"4.00"},9.48,"<1","N/A","http://selleckchem.com/products/sarafloxacin-hydrochloride.html","C20H17F2N3O3.HCl","Hydrochloride","A-56620 HCl","Cl.OC(=O)C1=CN(C2=CC=C(F)C=C2)C3=C(C=C(F)C(=C3)N4CCNCC4)C1=O",{"v":0,"d":"0.000"},0,0,0]
["S1986","Meclizine 2HCl","c5","L3800-53","in 2mM DMSO","FDA,DMF,NDC","USP42-NF37,KP Ⅹ,IP2010","Phase 2","CAR,Histamine Receptor","Neuronal Signaling","Meclizine (NSC 28728,Meclozine dihydrochloride) is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation properties, also an agonist ligand for mCAR (constitutive androstane receptor) and an inverse agonist for hCAR.",463.87,"1104-22-9",{"v":4,"d":"4.00"},8.62,"<1","N/A","http://selleckchem.com/products/meclizine-dihydrochloride.html","C25H27Cl2N2.2HCl","Dihydrochloride","NSC 28728,Meclozine dihydrochloride","Cl.Cl.CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(Cl)C=C4",{"v":0,"d":"0.000"},0,0,0]
["S2035","Epalrestat (ONO-2235)","d5","L3800-53","in 2mM DMSO","CFDA,PMDA","Martindale:The Extra Pharmacopoeia,JP17","Marketed","Aldose Reductase,Carbohydrate Metabolism","Metabolism","Epalrestat (ONO-2235) is an aldose reductase inhibitor with IC50 of 72 nM.",{"v":319.4,"d":"319.40"},"82159-09-9",{"v":3,"d":"3.00"},9.39,"<1","N/A","http://selleckchem.com/products/epalrestat.html","C15H13NO3S2","free base","ONO-2235","CC(=C/C1=CC=CC=C1)\\C=C2/SC(=S)N(CC(O)=O)C2=O",3.442,2,0,4]
["S2047","Lornoxicam","e5","L3800-53","in 2mM DMSO","DMF,CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia","Marketed","COX","Neuronal Signaling","Lornoxicam (Chlortenoxicam) is a non-steroidal COX-1/COX-2 inhibitor, used as an anti-inflammatory drug to treat pain, osteoarthritis, and rheumatoid arthritis.",371.82,"70374-39-9",{"v":3,"d":"3.00"},8.07,"<1","N/A","http://selleckchem.com/products/lornoxicam-xefo.html","C13H10ClN3O4S2","free base","Chlortenoxicam","CN1C(=C(O)C2=C(C=C(Cl)S2)[S]1(=O)=O)C(=O)NC3=NC=CC=C3",0.913,4,2,2]
["S2110","Vinpocetine","f5","L3800-53","in 2mM DMSO","DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,BP2017","Phase 1/2","Sodium Channel","Transmembrane Transporters","Vinpocetine (RGH-4405,Ethyl apovincaminate,AY 27255) is a selective inhibitor of voltage-sensitive sodium channel for the treatment of stroke, vascular dementia  and Alzheimer's disease.",350.45,"42971-09-5",{"v":3,"d":"3.00"},8.56,"<1","N/A","http://selleckchem.com/products/vinpocetine-cavinton.html","C22H26N2O2","free base","RGH-4405,Ethyl apovincaminate,AY 27255","CCOC(=O)C1=CC2(CC)CCCN3CCC4=C(C23)[N]1C5=CC=CC=C45",{"v":0,"d":"0.000"},0,0,0]
["S2150","Neratinib (HKI-272)","g5","L3800-53","in 2mM DMSO","FDA,EMA,NDC","N/A","Marketed","EGFR,HER2","Protein Tyrosine Kinase","Neratinib (HKI-272) is a highly selective HER2 and EGFR inhibitor with IC50 of 59 nM and 92 nM in cell-free assays; weakly inhibits KDR and Src, no significant inhibition to Akt, CDK1/2/4, IKK-2, MK-2, PDK1, c-Raf and c-Met. Phase 3.",557.04,"698387-09-6",{"v":5,"d":"5.00"},8.98,"<1","N/A","http://selleckchem.com/products/Neratinib(HKI-272).html","C30H29ClN6O3","free base","N/A","CCOC1=C(NC(=O)\\C=C\\CN(C)C)C=C2C(=C1)N=CC(=C2NC3=CC=C(OCC4=NC=CC=C4)C(=C3)Cl)C#N",4.881,5,2,11]
["S2152","Sitafloxacin Hydrate","h5","L3800-53","in 2mM DMSO","PMDA","Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics","Microbiology","Sitafloxacin Hydrate (DU-6859a) is a new-generation, broad-spectrum oral fluoroquinolone antibiotic.",436.84,"163253-35-8",{"v":4,"d":"4.00"},9.16,"<1","N/A","http://selleckchem.com/products/Sitafloxacin(DU-6859A).html","C19H18ClF2N3O3.3/2H2O","1.5 hydrate","DU-6859a","O.O.O.NC1CN(CC12CC2)C3=C(Cl)C4=C(C=C3F)C(=O)C(=CN4C5CC5F)C(O)=O.NC6CN(CC67CC7)C8=C(Cl)C9=C(C=C8F)C(=O)C(=CN9C%10CC%10F)C(O)=O",0.344,2,1,3]
["S2157","Taladegib (LY2940680)","a6","L3800-53","in 2mM DMSO","N/A","N/A","Phase 1/2","Hedgehog/Smoothened","Stem Cells & Wnt","Taladegib (LY2940680) binds to the Smoothened (Smo) receptor and potently inhibits Hedgehog (Hh) signaling. Phase 1/2.",{"v":512.5,"d":"512.50"},"1258861-20-9",{"v":5,"d":"5.00"},9.76,"<1","N/A","http://selleckchem.com/products/ly2940680.html","C26H24F4N6O","free base","N/A","C[N]1N=CC=C1C2=NN=C(N3CCC(CC3)N(C)C(=O)C4=C(C=C(F)C=C4)C(F)(F)F)C5=C2C=CC=C5",{"v":0,"d":"0.000"},0,0,0]
["S2206","Fostamatinib (R788) disodium","b6","L3800-53","in 2mM DMSO","FDA","N/A","Marketed","Syk","Angiogenesis","Fostamatinib disodium  (R788, Tamatinib Fosdium), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.",624.42,"1025687-58-4",{"v":6,"d":"6.00"},9.61,"<1","N/A","http://selleckchem.com/products/R788(Fostamatinib-disodium).html","C23H24FN6O9P.2Na","Sodium Salt","Tamatinib Fosdium","[Na+].[Na+].COC1=C(OC)C(=CC(=C1)NC2=NC=C(F)C(=N2)NC3=CC=C4OC(C)(C)C(=O)N(CO[P]([O-])([O-])=O)C4=N3)OC",{"v":0,"d":"0.000"},0,0,0]
["S2232","Ketanserin","c6","L3800-53","in 2mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","Phase 4","5-HT Receptor","Neuronal Signaling","Ketanserin (R41468, Ketanserinum) is a specific 5-HT2A serotonin receptor antagonist with Ki of 2.5 nM for rat and human 5-HT2A, used as an antihypertensive drug.",395.43,"74050-98-9",{"v":2,"d":"2.00"},5.06,"<1","N/A","http://selleckchem.com/products/Ketanserin-Vulketan-Gel.html","C22H22FN3O3","Free Base","R41468, Ketanserinum","FC1=CC=C(C=C1)C(=O)C2CCN(CC2)CCN3C(=O)NC4=CC=CC=C4C3=O",2.991,3,1,5]
["S2251","(-)-Huperzine A (HupA)","d6","L3800-53","in 2mM DMSO","DMF","CP2005","Phase 2","AChR,GluR","Neuronal Signaling","(-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4.",242.32,"102518-79-6",0.66,2.72,"<1","N/A","http://selleckchem.com/products/(-)-Huperzine-A.html","C15H18N2O","Free Base","N/A","C\\C=C/1C2CC3=C(C=CC(=O)N3)C1(N)CC(=C2)C",1.056,1,2,0]
["S2292","Diosmin","e6","L3800-53","in 2mM DMSO","DMF,CFDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,BP2017","Phase 4","AhR","Metabolism","Diosmin is an agonist of the aryl hydrocarbon receptor (AhR). Diosmin is a semisynthetic phlebotropic agent and a flavonoid found in a variety of citrus fruits.",608.55,"520-27-4",{"v":6,"d":"6.00"},9.86,"<1","N/A","http://selleckchem.com/products/Diosmin.html","C28H32O15","Free Base","N/A","COC1=C(O)C=C(C=C1)C2=CC(=O)C3=C(O2)C=C(OC4OC(COC5OC(C)C(O)C(O)C5O)C(O)C(O)C4O)C=C3O",-0.395,7,8,7]
["S2424","Hypoxanthine","f6","L3800-53","in 2mM DMSO","DMF","USP42-NF37,EP9.2,BP2017","N/A","Others","Others","Hypoxanthine, a naturally occurring purine derivative, an intermediate product of uric acid synthesis, formed from adenylic acid and itself a precursor of xanthine.",136.11,"68-94-0",{"v":0.4,"d":"0.40"},2.94,"<1","N/A","http://selleckchem.com/products/hypoxanthine.html","C5H4N4O","Free Base","N/A","O=C1NC=NC2=C1[NH]C=N2",-0.532,3,2,0]
["S2476","Itraconazole (R 51211)","g6","L3800-53","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,JP17,BP2017","Marketed","Autophagy,Fungal,Hedgehog/Smoothened,P450 (e.g. CYP17)","Stem Cells & Wnt","Itraconazole (R 51211) is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy.",705.65,"84625-61-6",{"v":7,"d":"7.00"},9.92,"<1","N/A","http://selleckchem.com/products/Itraconazole(Sporanox).html","C35H38Cl2N8O4","free base","R 51211","CCC(C)N1N=CN(C1=O)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(OCC5COC(C[N]6C=NC=N6)(O5)C7=CC=C(Cl)C=C7Cl)C=C4",6.434,7,0,11]
["S2530","7-Aminocephalosporanic acid","h6","L3800-53","in 2mM DMSO","DMF","N/A","N/A","Antibiotics","Microbiology","7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates.",272.28,"957-68-6",{"v":1,"d":"1.00"},3.67,"<1","N/A","http://selleckchem.com/products/7-Aminocephalosporanic-acid.html","C10H12N2O5S","Free Base","N/A","CC(=O)OCC1=C(N2C(SC1)C(N)C2=O)C(O)=O",-3.745,4,1,4]
["S2582","Trazodone HCl","a7","L3800-53","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017","Marketed","5-HT Receptor","Neuronal Signaling","Trazodone HCl (AF-1161, KB-831) is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.",408.32,"25332-39-2",{"v":4,"d":"4.00"},{"v":9.8,"d":"9.80"},"<1","N/A","http://selleckchem.com/products/trazodone-hydrochloride-desyrel.html","C19H22ClN5O.HCl","Hydrochloride","AF-1161, KB-831","Cl.ClC1=CC(=CC=C1)N2CCN(CCCN3N=C4C=CC=CN4C3=O)CC2",{"v":0,"d":"0.000"},0,0,0]
["S2597","Oseltamivir Phosphate","b7","L3800-53","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,Ph.Int_6th,BP2017,IP2010","Marketed","Influenza Virus,Neuraminidase","Microbiology","Oseltamivir Phosphate(Tamiflu) is a potent and selective inhibitor of the neuraminidase that is essential for replication of influenza A and B viruses, used to prevent influenza.",{"v":410.4,"d":"410.40"},"204255-11-8",{"v":4,"d":"4.00"},9.75,"<1","N/A","http://selleckchem.com/products/oseltamivir-phosphate-Tamiflu.html","C16H28N2O4.H3PO4","Phosphate salt","Tamiflu","CCOC(=O)C1=CC(OC(CC)CC)C(NC(C)=O)C(N)C1.O[P](O)(O)=O",0.577,4,2,8]
["S2628","Gedatolisib (PKI-587)","c7","L3800-53","in 2mM DMSO","N/A","N/A","Phase 3","mTOR,PI3K","PI3K/Akt/mTOR","Gedatolisib (PF-05212384, PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ and mTOR with IC50 of 0.4 nM, 5.4 nM and 1.6 nM in cell-free assays, respectively. Phase 2.",615.73,"1197160-78-3",{"v":2,"d":"2.00"},3.25,"<1","N/A","http://selleckchem.com/products/pki587.html","C32H41N9O4","Free Base","PF-05212384","CN(C)C1CCN(CC1)C(=O)C2=CC=C(NC(=O)NC3=CC=C(C=C3)C4=NC(=NC(=N4)N5CCOCC5)N6CCOCC6)C=C2",2.525,7,2,7]
["S2684","Pidnarulex (CX-5461)","d7","L3800-53","in 2mM DMSO","N/A","N/A","Phase 2","DNA/RNA Synthesis","DNA Damage/DNA Repair","Pidnarulex (CX-5461) is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM in HCT-116, A375, and MIA PaCa-2 cells, has no effect on Pol II, and possesses 250- to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation.",513.61,"1138549-36-6",{"v":2,"d":"2.00"},3.89,"<1","N/A","http://www.selleck.cn/products/cx-5461.html","C27H27N7O2S","Free Base","N/A","CN1CCCN(CC1)C2=CC=C3C(=O)C(=C4SC5=C(C=CC=C5)N4C3=N2)C(=O)NCC6=CN=C(C)C=N6",3.188,5,1,4]
["S2735","MK-8776 (SCH 900776)","e7","L3800-53","in 2mM DMSO","N/A","N/A","Phase 2","CDK,Chk","Cell Cycle","MK-8776 (SCH 900776) is a selective Chk1 inhibitor with IC50 of 3 nM in a cell-free assay. It shows 500-fold selectivity against Chk2. Phase 2.",376.25,"891494-63-6",{"v":3,"d":"3.00"},7.97,"<1","N/A","http://selleckchem.com/products/sch-900776.html","C15H18BrN7","Free Base","N/A","C[N]1C=C(C=N1)C2=C3N=C(C4CCCNC4)C(=C(N)[N]3N=C2)Br",{"v":1.32,"d":"1.320"},3,2,2]
["S2788","Capmatinib (INCB28060)","f7","L3800-53","in 2mM DMSO","N/A","N/A","Phase 3","Apoptosis related,c-Met,Wnt/beta-catenin","Protein Tyrosine Kinase","Capmatinib (INCB28060, INC280, NVP-INC280) is a novel, ATP-competitive inhibitor of c-MET with IC50 of 0.13 nM in a cell-free assay, inactive against RONβ, as well as EGFR and HER-3. Capmatinib (INCB28060) inhibits Wnt/β-catenin and EMT signaling pathways and induces apoptosis in diffuse gastric cancer positive for c-MET amplification. Phase 1.",412.42,"1029712-80-8",{"v":2,"d":"2.00"},4.85,"<1","N/A","http://selleckchem.com/products/incb28060.html","C23H17FN6O","Free Base","INC280, NVP-INC280","CNC(=O)C1=CC=C(C=C1F)C2=N[N]3C(=CN=C3N=C2)CC4=CC=C5N=CC=CC5=C4",3.246,5,1,4]
["S2920","Mozavaptan","g7","L3800-53","in 2mM DMSO","marketed in Japan","Martindale:The Extra Pharmacopoeia","Marketed","Vasopressin Receptor","GPCR & G Protein","Mozavaptan (OPC-31260) is a novel competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM, respectively.",427.54,"137975-06-5",{"v":1,"d":"1.00"},2.34,"<1","N/A","http://selleckchem.com/products/mozavaptan.html","C27H29N3O2","Free Base","OPC-31260","CN(C)C1CCCN(C(=O)C2=CC=C(NC(=O)C3=C(C)C=CC=C3)C=C2)C4=C1C=CC=C4",4.654,2,1,4]
["S3041","Droxidopa","h7","L3800-53","in 2mM DMSO","FDA,CFDA,DMF,NDC,PMDA","Martindale the Extra Pharmacopoei,JP17","Marketed","Adrenergic Receptor","GPCR & G Protein","Droxidopa (L-DOPS) is a psychoactive drug and acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline).",213.19,"23651-95-8",{"v":2,"d":"2.00"},9.38,{"v":1,"d":"1.00"},4.69,"http://www.selleck.cn/products/droxidopa-l-dops.html","C9H11NO5","Free Base","L-DOPS","NC(C(O)C1=CC(=C(O)C=C1)O)C(O)=O",-2.921,1,4,3]
["S3059","Enrofloxacin","a8","L3800-53","in 2mM DMSO","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,BP2017","N/A","Antibiotics","Microbiology","Enrofloxacin (BAY-Vp2674, PD160788) is a fluoroquinolone antibiotic.",359.39,"93106-60-6",{"v":3,"d":"3.00"},8.35,"<1","N/A","http://selleckchem.com/products/enrofloxacin.html","C19H22FN3O3","free base","BAY-Vp2674, PD160788","CCN1CCN(CC1)C2=CC3=C(C=C2F)C(=O)C(=CN3C4CC4)C(O)=O",{"v":0,"d":"0.000"},0,0,0]
["S3064","Ambroxol HCl","b8","L3800-53","in 2mM DMSO","CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,EP9.2,EP9.1,BP2017,IP2010","N/A","Sodium Channel","Transmembrane Transporters","AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. Phase 3.",414.56,"23828-92-4",{"v":4,"d":"4.00"},9.65,"<1","N/A","http://selleckchem.com/products/ambroxol-hcl.html","C13H18Br2N2O.HCl","Hydrochloride","N/A","Cl.NC1=C(Br)C=C(Br)C=C1CNC2CCC(O)CC2",3.121,0,3,3]
["S3636","Cefadroxil hydrate","c8","L3800-53","in 2mM DMSO","FDA,DMF,CFDA,NDC,HMA","KP Ⅹ,EP9.2,BP2017","Phase 4","Antibiotics,Bacterial","Microbiology","Cefadroxil(BL-S 578 hydrate) is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.",{"v":381.4,"d":"381.40"},"66592-87-8",1.76,4.61,"N/A","N/A","http://selleckchem.com/products/cefadroxil-hydrate.html","C16H17N3O5S.H2O","hydrate","BL-S 578 hydrate","O.CC1=C(N2C(SC1)C(NC(=O)C(N)C3=CC=C(O)C=C3)C2=O)C(O)=O",-2.704,3,3,4]
["S3721","Bilastine","d8","L3800-53","in 2mM DMSO","DMF,PMDA,HMA","N/A","Marketed","Histamine Receptor","Neuronal Signaling","Bilastine is a new, well-tolerated, nonsedating H1 receptor antihistamine and has a rapid onset and prolonged duration of action.",463.61,"202189-78-4",{"v":1,"d":"1.00"},2.16,"<1","N/A","http://selleckchem.com/products/bilastine.html","C28H37N3O3","free base","N/A","CCOCC[N]1C(=NC2=C1C=CC=C2)C3CCN(CC3)CCC4=CC=C(C=C4)C(C)(C)C(O)=O",{"v":2.07,"d":"2.070"},3,0,10]
["S3770","Sodium Aescinate","e8","L3800-53","in 2mM DMSO","CFDA","CP2005","N/A","NF-κB","NF-κB","Sodium Aescinate (SA, Escin Sodium Salt) is a widely-applied triterpene saponin product derived from horse chestnut seeds, possessing vasoactive and organ-protective activities with oral or injection administration in the clinic.  Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway.",1123.21,"20977-05-3",{"v":10,"d":"10.00"},{"v":8.9,"d":"8.90"},"N/A","N/A","http://selleckchem.com/products/sodium-aescinate.html","C54H83NaO23","sodium salt","Escin sodium salt","CC(OC(C)=O)C(C)C(=O)OCC12C(O)C3OC1CC4(C)C(=CCC5C6(C)CCC(OC7OC(C(OC8OC(CO)C(O)C(O)C8O)C(O)C7OC9OCC(O)C(O)C9O)C(=O)O[Na])C(C)(CO)C6CCC45C)C2CC3(C)C",-0.485,13,10,17]
["S3801","Sodium Houttuyfonate","f8","L3800-53","in 2mM DMSO","CFDA","N/A","N/A","Anti-infection","Microbiology","Sodium Houttuyfonate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.",330.42,"1847-58-1",{"v":2,"d":"2.00"},6.05,"<1","N/A","http://selleckchem.com/products/sodium-houttuyfonate.html","C14H27O5S.Na","sodium salt","N/A","[Na+].CCCCCCCCCCCCOC(=O)C[S]([O-])(=O)=O",2.026,2,0,14]
["S3821","Nuciferine","g8","L3800-53","in 2mM DMSO","N/A","CP2005","N/A","5-HT Receptor,5-HT Receptor,Dopamine Receptor","Neuronal Signaling","Nuciferine (Sanjoinine E, (-)-Nuciferine, VLT 049) is a major active aporphine alkaloid from the leaves of N. nucifera Gaertn and possesses anti-hyperlipidemia, anti-hypotensive, anti-arrhythmic, and insulin secretagogue activities. Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 μM) and 5-HT6 (EC50=700 nM), an agonist at 5-HT1A (EC50=3.2 μM) and D4 (EC50=2 μM) receptor.",295.38,"475-83-2",{"v":2,"d":"2.00"},6.77,"<1","N/A","http://selleckchem.com/products/nuciferine.html","C19H21NO2","free base","Sanjoinine E, (-)-Nuciferine, VLT 049","COC1=C(OC)C2=C3C(CC4=C2C=CC=C4)N(C)CCC3=C1",3.567,2,0,2]
["S3891","Vincamine","h8","L3800-53","in 2mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Vincamine (Angiopac, Devincan, Equipur, Minorin, Novicet, Oxybral, Perval, Sostenil, Tripervan), an indole alkaloid found in the leaves of V. minor and C. roseus, is a peripheral vasodilator that increases blood flow to the brain.",354.44,"1617-90-9",{"v":3,"d":"3.00"},8.46,"N/A","N/A","http://selleckchem.com/products/vincamine.html","C21H26N2O3","free base","Angiopac, Devincan, Equipur, Minorin, Novicet, Oxybral, Perval, Sostenil, Tripervan","CCC12CCCN3CCC4=C(C13)[N](C5=CC=CC=C45)C(O)(C2)C(=O)OC",3.546,2,0,3]
["S4033","Sennoside A","a9","L3800-53","in 2mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","MAO","Metabolism","Sennoside A (NSC 112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.",862.74,"81-27-6","N/A",{"v":2,"d":"2.00"},"<1","N/A","http://selleckchem.com/products/sennoside-a.html","C42H38O20","Free Base","NSC 112929","OCC1OC(OC2=CC=CC3=C2C(=O)C4=C(O)C=C(C=C4C3C5C6=C(C(=O)C7=C(O)C=C(C=C57)C(O)=O)C(=CC=C6)OC8OC(CO)C(O)C(O)C8O)C(O)=O)C(O)C(O)C1O",0.409,8,10,9]
["S4126","Retinyl (Vitamin A) Palmitate","b9","L3800-53","in 2mM DMSO","FDA,DMF,CFDA,NDC","USP42-NF37","N/A","Vitamin","Metabolism","Retinyl (Vitamin A) Palmitate is a more stable, synthetic version of the essential nutrient vitamin A joined to palmitic acid.",524.86,"79-81-2",{"v":3,"d":"3.00"},5.72,"<1","N/A","http://selleckchem.com/products/vitamin-a-palmitate.html","C36H60O2","Free Base","Vitamin A palmitate","CCCCCCCCCCCCCCCC(=O)OC/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C",12.293,2,0,21]
["S4142","Clopidol","c9","L3800-53","in 2mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Anti-infection","Microbiology","Clopidol (WR 61112) is an antiprotozoal agent.",192.04,"2971-90-6",{"v":1,"d":"1.00"},5.21,"<1","N/A","http://selleckchem.com/products/clopidol.html","C7H7Cl2NO","free base","WR 61112","CC1=C(Cl)C(=C(Cl)C(=N1)C)O",2.331,1,1,0]
["S4156","Chlortetracycline HCl (NSC 13252)","d9","L3800-53","in 2mM DMSO","FDA,DMF,CFDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.1,BP2017,Ph.Int_5th","N/A","Antibiotics,Antineoplastic and Immunosuppressive Antibiotics","Microbiology","Chlortetracycline HCl (NSC 13252, 7-Chlorotetracycline, Aureomycin monohydrochloride) is the first identified tetracycline antibiotic.",515.34,"64-72-2",{"v":5,"d":"5.00"},{"v":9.7,"d":"9.70"},{"v":1,"d":"1.00"},1.94,"http://selleckchem.com/products/chlortetracycline-hcl.html","C22H23ClN2O8.HCl","Hydrochloride","7-Chlorotetracycline HCl, Aureomycin monohydrochloride","Cl.CN(C)C1C2CC3C(=C(O)C2(O)C(=O)C(=C1O)C(N)=O)C(=O)C4=C(C(=CC=C4O)Cl)C3(C)O",{"v":0,"d":"0.000"},0,0,0]
["S4218","Amoxapine","e9","L3800-53","in 2mM DMSO","FDA,DMF,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,JP17","N/A","Amino acid transporter,GlyT","Neuronal Signaling","Amoxapine (CL 67772,Asendin) is a tricyclic dibenzoxazepine (an N-aryl piperazine) which acts similarly to several other tricyclic antidepressants, amoxapine inhibits GLYT2a transport activity with IC50 of 92 μM.",313.78,"14028-44-5",{"v":3,"d":"3.00"},9.56,"<1","N/A","http://selleckchem.com/products/amoxapine.html","C17H16ClN3O","free base","CL 67772,Asendin","ClC1=CC2=C(OC3=C(C=CC=C3)N=C2N4CCNCC4)C=C1",{"v":0,"d":"0.000"},0,0,0]
["S4262","Ebastine","f9","L3800-53","in 2mM DMSO","CFDA,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.6,KP Ⅹ,JP17,BP2017","Marketed","Histamine Receptor","Neuronal Signaling","Ebastine(LAS-W 090,RP64305) is a potent H1-histamine receptor antagonist, used for allergic disorders.",469.66,"90729-43-4",{"v":4,"d":"4.00"},8.52,"<1","N/A","http://selleckchem.com/products/ebastine.html","C32H39NO2","free base","LAS-W 090,RP64305","CC(C)(C)C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)OC(C3=CC=CC=C3)C4=CC=CC=C4",6.582,2,0,10]
["S4605","Folic acid","g9","L3800-53","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th.JP17,BP2017,IP2010","N/A","Vitamin","Metabolism","Folic acid (Folacin, Vitamin B9, Vitamin M, Pteroylglutamic acid, Folate), a B vitamin, plays an important role in cell division and in the synthesis of amino acids and nucleic acids like DNA.",{"v":441.4,"d":"441.40"},"59-30-3",{"v":2,"d":"2.00"},4.53,"<1","N/A","http://selleckchem.com/products/folic-acid.html","C19H19N7O6","free base","Folacin, Vitamin B9, Vitamin M, Pteroylglutamic acid, Folate","NC1=NC(=O)C2=C(N1)N=CC(=N2)CNC3=CC=C(C=C3)C(=O)NC(CCC(O)=O)C(O)=O",-0.232,7,4,9]
["S4642","Dolutegravir Sodium","h9","L3800-53","in 2mM DMSO","FDA,DMF,EMA,NDC,PMDA","N/A","Marketed","Integrase","Microbiology","Dolutegravir Sodium (GSK-1349572A) is a HIV integrase inhibitor with IC50 of 2.7 nM.",441.36,"1051375-19-9",{"v":2,"d":"2.00"},4.53,"<1","N/A","http://www.selleck.cn/products/dolutegravir-sodium.html","C20H19F2N3O5.Na","Sodium","GSK-1349572A","CC1CCOC2CN3C=C(C(=O)NCC4=C(F)C=C(F)C=C4)C(=O)C(=C3C(=O)N12)O[Na]",0.391,5,1,4]
["S4654","Netupitant","a10","L3800-53","in 2mM DMSO","FDA,DMF,NDC,HMA","N/A","Phase 2","Neurokinin Receptor","Neuronal Signaling","Netupitant (CID6451149) is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity.",578.59,"290297-26-6",{"v":2,"d":"2.00"},3.46,"<1","N/A","http://selleckchem.com/products/netupitant.html","C30H32F6N4O","Free Base","CID6451149, CID 6451149, CID-6451149","CN1CCN(CC1)C2=CC(=C(C=N2)N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C4=CC=CC=C4C",7.132,2,0,7]
["S4930","Cetilistat","b10","L3800-53","in 2mM DMSO","PMDA","N/A","Marketed","Lipase","Metabolism","Cetilistat (ATL962) is a novel highly lipophilic benzoxazinone that inhibits gastrointestinal and pancreatic lipases. It shows a good safety and tolerability profile in vivo",401.58,"282526-98-1",{"v":3,"d":"3.00"},7.47,"<1","N/A","http://selleckchem.com/products/cetilistat.html","C25H39NO3","free base","ATL962","CCCCCCCCCCCCCCCCOC1=NC2=C(C=C(C)C=C2)C(=O)O1",9.409,4,0,16]
["S5018","Mebhydrolin napadisylate","c10","L3800-53","in 2mM DMSO","marketed in Bangladesh and Russia","N/A","N/A","ADC Cytotoxin,Histamine Receptor","Neuronal Signaling","Mebhydrolin Napadisylate (Diazoline, Diazolin, Incidal, Omeril) is classified as an antihistamine drug classes used to treat allergies.",841.05,"6153-33-9",{"v":8,"d":"8.00"},9.51,"N/A","N/A","http://selleckchem.com/products/mebhydrolin-napadisylate.html","C48H48N4O6S2","salt","Diazoline, Diazolin, Incidal, Omeril","CN1CCC2=C(C1)C3=C(C=CC=C3)[N]2CC4=CC=CC=C4.CN5CCC6=C(C5)C7=C(C=CC=C7)[N]6CC8=CC=CC=C8.O[S](=O)(=O)C9=C%10C=CC=C(C%10=CC=C9)[S](O)(=O)=O",9.536,0,0,6]
["S5035","6-Aminopenicillanic acid","d10","L3800-53","in 2mM DMSO","DMF","BP2019,EP9.1,USP32-NF27","N/A","Antibiotics","Microbiology","6-Aminopenicillanic acid (6-APA) is the central component of penicillin β-lactam antibiotics which are generated by Penicillium. It is used as precursor for antibiotic compounds ampicillin and amoxicillin.",216.26,"551-16-6",{"v":1,"d":"1.00"},4.62,"<1","N/A","http://selleckchem.com/products/6-aminopenicillanic-acid.html","C8H12N2O3S","free base","N/A","CC1(C)SC2C(N)C(=O)N2C1C(O)=O",-3.076,2,1,1]
["S5232","Alectinib (CH5424802) hydrochloride","e10","L3800-53","in 2mM DMSO","FDA,DMF,NDC","N/A","Marketed","ALK","Protein Tyrosine Kinase","Alectinib (AF802, CH5424802, RO5424802, RG-7853) is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase.",519.08,"1256589-74-8",{"v":2,"d":"2.00"},3.85,"<1","N/A","http://selleckchem.com/products/alectinib-hydrochloride.html","C30H34N4O2.HCl","hydrochloride","AF802, RO5424802, RG-7853","Cl.CCC1=C(C=C2C(=C1)C(=O)C3=C([NH]C4=C3C=CC(=C4)C#N)C2(C)C)N5CCC(CC5)N6CCOCC6",5.585,2,1,3]
["S5272","Toceranib phosphate","f10","L3800-53","in 2mM DMSO","EMA","N/A","Marketed","PDGFR,VEGFR","Protein Tyrosine Kinase","Toceranib phosphate (Palladia, SU11654), the phosphate salt of toceranib, is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family, including Flk-1/KDR, PDGFR, and Kit with Ki values of 6 nM and 5 nM for Flk-1/KDR and PDGFRβ, respectively.",494.45,"874819-74-6",{"v":2,"d":"2.00"},4.04,{"v":2,"d":"2.00"},4.04,"https://www.selleckchem.com/products/toceranib-phosphate.html","C22H25FN4O2.H3O4P","phosphate","Palladia, SU11654","CC1=C(C(=C([NH]1)\\C=C2/C(=O)NC3=C2C=C(F)C=C3)C)C(=O)NCCN4CCCC4.O[P](O)(O)=O",2.292,2,3,5]
["S5499","Amantadine","g10","L3800-53","in 2mM DMSO","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2016,IP2010","Marketed","Influenza Virus","Microbiology","Amantadine (1-Adamantanamine, 1-Adamantylamine, 1-Aminoadamantane) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is an M2 inhibitor which blocks the ion channel formed by the M2 protein that spans the viral membrane.",151.25,"768-94-5",{"v":1,"d":"1.00"},6.61,"N/A","N/A","http://selleckchem.com/products/amantadine.html","C10H17N","free base","1-Adamantanamine, 1-Adamantylamine, 1-Aminoadamantane","N[C]12C[CH]3[CH2]C([CH2][CH](C3)C1)C2",1.495,0,1,0]
["S5601","Balofloxacin Dihydrate","h10","L3800-53","in 2mM DMSO","CFDA","Martindale:The Extra Pharmacopoeia","Marketed","Antibiotics","Microbiology","Balofloxacin Dihydrate is an orally active fluoroquinolone antibiotic.",425.45,"151060-21-8",{"v":2,"d":"2.00"},{"v":4.7,"d":"4.70"},"<1","N/A","https://www.selleckchem.com/products/balofloxacin-dihydrate.html","C20H28FN3O6","free base","Neuroquinoron","O.O.CNC1CCCN(C1)C2=C(F)C=C3C(=O)C(=CN(C4CC4)C3=C2OC)C(O)=O",-1.029,3,1,5]
["S5677","Xanthopterin Hydrate","a11","L3800-53","in 2mM DMSO","N/A","Martindale:The Extra Pharmacopoeia","N/A","Others","Others","Xanthopterin, isolated from butterfly wings and found in many other sources, replace folic acid in the nutrition of many animal species.",197.15,"5979-01-1",{"v":1,"d":"1.00"},5.07,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/xanthopterin-hydrate.html","C6H7N5O3","Hydrate","N/A","O.NC1=NC(=C2N=C(O)C=NC2=N1)O",-0.128,4,3,0]
["S5712","Zofenopril calcium","b11","L3800-53","in 2mM DMSO","DMF,HMA","Martindale:The Extra Pharmacopoeia","Marketed","RAAS","Endocrinology & Hormones","Zofenopril calcium (SQ-26991) is an angiotensin-converting enzyme (ACE) inhibitor that protects the heart and helps reduce high blood pressure.",897.17,"81938-43-4","N/A",{"v":2,"d":"2.00"},"<1","N/A","http://selleckchem.com/products/zofenopril-calcium.html","C44H44CaN2O8S4","calcium salt","SQ-26991","CC(CSC(=O)C1=CC=CC=C1)C(=O)N2CC(CC2C(=O)O[Ca]OC(=O)C3CC(CN3C(=O)C(C)CSC(=O)C4=CC=CC=C4)SC5=CC=CC=C5)SC6=CC=CC=C6",8.055,8,0,20]
["S5908","Garenoxacin","c11","L3800-53","in 2mM DMSO","DMF,marketed in Japan","Martindale:The Extra Pharmacopoeia","Marketed","Anti-infection","Microbiology","Garenoxacin (T-3811ME, BMS-284756) is a novel des-F(6) quinolone that has been shown to be effective in vitro against a wide range of clinically important pathogens, including gram-positive and gram-negative aerobes and anaerobes.",426.41,"194804-75-6",{"v":2,"d":"2.00"},4.69,"<1","N/A","http://www.selleckchem.com/products/garenoxacin.html","C23H20F2N2O4","Free Base","T-3811ME, BMS-284756","CC1NCC2=C1C=CC(=C2)C3=C(OC(F)F)C4=C(C=C3)C(=O)C(=CN4C5CC5)C(O)=O",0.934,3,1,5]
["S6001","pomaglumetad (LY404039)","d11","L3800-53","in 2mM DMSO","N/A","N/A","Phase 3","GluR","Neuronal Signaling","LY404039 is a potent agonist of recombinant human mGlu2/mGlu3 receptors with Ki of 149 nM/92 nM, shows >100-fold selectivity over ionotropic glutamate receptors, glutamate transporters, and other receptors. Phase 3.",235.22,"635318-11-5",{"v":1,"d":"1.00"},4.25,"<1","N/A","http://selleckchem.com/products/LY2140023(LY404039).html","C7H9NO6S","Free Base","N/A","NC1(C[S](=O)(=O)C2C(C12)C(O)=O)C(O)=O",-4.682,4,1,2]
["S6632","Mirogabalin (DS-5565)","e11","L3800-53","in 2mM DMSO","PMDA","N/A","Marketed","Others","Others","Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand that has been used in trials studying the treatment of Post-herpetic Neuralgia, Pain Associated With Fibromyalgia, and Diabetic peripheral neuropathic pain.",209.28,"1138245-13-2",{"v":2,"d":"2.00"},9.56,{"v":3,"d":"3.00"},14.33,"http://www.selleck.cn/products/mirogabalin-ds-5565.html","C12H19NO2","Free Base","N/A","CCC1=CC2C(C1)CC2(CN)CC(O)=O",-1.352,1,1,4]
["S6642","Branaplam (LMI070)","f11","L3800-53","in 2mM DMSO","N/A","N/A","Phase 2","SMN","DNA Damage/DNA Repair","Branaplam (LMI070) is a highly selective, small-molecule splicing modulators of survival motor neuron‑2 (SMN2) with an EC50 of 0.02 μM.",393.48,"1562338-42-4",{"v":3,"d":"3.00"},7.62,"<1","N/A","http://www.selleck.cn/products/branaplam-lmi070.html","C22H27N5O2","Free Base","N/A","CC1(C)CC(CC(C)(C)N1)OC2=NN=C(C=C2)C3=C(O)C=C(C=C3)C4=C[NH]N=C4",3.141,4,3,4]
["S7061","GSK126","g11","L3800-53","in 2mM DMSO","N/A","N/A","Phase 1","EZH1/2,Histone Methyltransferase","Epigenetics","GSK126 (GSK2816126A, GSK2816126) is a potent, highly selective EZH2 methyltransferase inhibitor with IC50 of 9.9 nM, >1000-fold selective for EZH2 over 20 other human methyltransferases.",526.67,"1346574-57-9",{"v":3,"d":"3.00"},{"v":5.7,"d":"5.70"},"<1","N/A","http://selleckchem.com/products/gsk126.html","C31H38N6O2","Free Base","GSK2816126A, GSK2816126","CCC(C)[N]1C=C(C)C2=C(C=C(C=C12)C3=CC=C(N=C3)N4CCNCC4)C(=O)NCC5=C(C)C=C(C)NC5=O",4.114,3,3,7]
["S7128","Tazemetostat (EPZ-6438)","h11","L3800-53","in 2mM DMSO","N/A","N/A","Phase 2","EZH1/2,Histone Methyltransferase","Epigenetics","Tazemetostat (EPZ-6438, E7438) is a potent, and selective EZH2 inhibitor with Ki and IC50 of 2.5 nM and 11 nM in cell-free assays, exhibiting a 35-fold selectivity versus EZH1 and >4,500-fold selectivity relative to 14 other HMTs.",572.74,"1403254-99-8",{"v":5,"d":"5.00"},8.73,"<1","N/A","http://selleckchem.com/products/epz-6438.html","C34H44N4O4","free base","E7438","CCN(C1CCOCC1)C2=C(C)C(=CC(=C2)C3=CC=C(CN4CCOCC4)C=C3)C(=O)NCC5=C(C)C=C(C)NC5=O",3.506,4,2,9]
["S7221","Vesatolimod (GS-9620)","a2","L3800-54","in 2mM DMSO","N/A","N/A","Phase 2","TLR","Immunology & Inflammation","Vesatolimod (GS-9620) is a potent and selective orally active small molecule agonist of Toll-like receptor 7.",410.51,"1228585-88-3",{"v":1,"d":"1.00"},2.44,"<1","N/A","http://selleckchem.com/products/gs-9620.html","C22H30N6O2","Free Base","N/A","CCCCOC1=NC(=C2NC(=O)CN(CC3=CC=CC(=C3)CN4CCCC4)C2=N1)N",3.302,4,2,8]
["S7518","Voreloxin (SNS-595) hydrochloride","b2","L3800-54","in 2mM DMSO","N/A","N/A","Phase 3","Topoisomerase","DNA Damage/DNA Repair","Voreloxin hydrochloride (SNS-595, Vosaroxin) is a potent Topoisomerase II inhibitor with broad-spectrum anti-tumor activity. Phase 2.",{"v":437.9,"d":"437.90"},"175519-16-1",{"v":1,"d":"1.00"},2.28,{"v":1,"d":"1.00"},2.28,"http://selleckchem.com/products/voreloxin-sns-595.html","C18H20ClN5O4S","hydrochloride","Vosaroxin","Cl.CNC1CN(CC1OC)C2=NC3=C(C=C2)C(=O)C(=CN3C4=NC=CS4)C(O)=O",-1.138,5,1,5]
["S7756","Indoximod (NLG-8189）","d2","L3800-54","in 2mM DMSO","N/A","N/A","Phase 2/3","IDO/TDO","Metabolism","Indoximod (NLG-8189, 1-Methyl-D-tryptophan, 1-MT), a methylated tryptophan, acts as an IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor, and reverses IDO-mediated immune suppression. Phase 2.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!",218.25,"110117-83-4",{"v":1,"d":"1.00"},4.58,"<1","N/A","http://selleckchem.com/products/indoximod-nlg-8189.html","C12H14N2O2","Free Base","1-Methyl-D-tryptophan, 1-MT","C[N]1C=C(CC(N)C(O)=O)C2=CC=CC=C12",-1.106,1,1,3]
["S7842","LY3009120","e2","L3800-54","in 2mM DMSO","N/A","N/A","Phase 1","Autophagy,Raf","MAPK","LY03009120 (DP-4978) is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for A-raf, B-Raf, and C-Raf in A375 cells, respectively. LY03009120 induces autophagy. Phase 1.",424.51,"1454682-72-4",{"v":3,"d":"3.00"},7.07,"<1","N/A","http://selleckchem.com/products/ly3009120.html","C23H29FN6O","Free Base","DP-4978","CNC1=NC=C2C=C(C(=NC2=N1)C)C3=CC(=C(F)C=C3C)NC(=O)NCCC(C)(C)C",4.158,4,3,6]
["S7846","Dubermatinib(TP-0903)","f2","L3800-54","in 2mM DMSO","N/A","N/A","Phase 1/2","Apoptosis related,Axl","Protein Tyrosine Kinase","TP-0903 is a potent and selective AXL Inhibitor with IC50 of 27 nM. TP-0903 is highly effective in inducing apoptosis.",516.06,"1341200-45-0",{"v":3,"d":"3.00"},5.81,"<1","N/A","http://selleckchem.com/products/tp-0903.html","C24H30ClN7O2S","Free Base","N/A","CN1CCN(CC1)CC2=CC=C(NC3=NC=C(Cl)C(=N3)NC4=CC=CC=C4[S](=O)(=O)N(C)C)C=C2",4.023,4,2,8]
["S8138","Molidustat (BAY 85-3934)","g2","L3800-54","in 2mM DMSO","N/A","N/A","Phase 3","HIF","Angiogenesis","Molidustat (BAY 85-3934) is a potent hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor with IC50 of 480 nM, 280 nM, and 450 nM for PHD1, PHD2, and PHD, respectively. Phase 2.",{"v":314.3,"d":"314.30"},"1154028-82-6",{"v":3,"d":"3.00"},9.55,"<1","N/A","http://selleckchem.com/products/molidustat-(bay85-3934).html","C13H14N8O2","free base","N/A","O=C1N(NC=C1[N]2C=CN=N2)C3=NC=NC(=C3)N4CCOCC4",{"v":0,"d":"0.000"},0,0,0]
["S8229","Brigatinib (AP26113)","h2","L3800-54","in 2mM DMSO","FDA,EMA,NDC","N/A","Marketed","ALK,EGFR,FLT3,IGF-1R,ROS1","Angiogenesis","Brigatinib (AP26113) is a potent and selective ALK (IC50, 0.6 nM) and ROS1 (IC50, 0.9 nM) inhibitor. It also inhibits IGF-1R, FLT3, and mutant variants of FLT3 (D835Y) and EGFR with lower potentcy.",584.09,"1197953-54-0",{"v":3,"d":"3.00"},5.14,"<1","N/A","http://www.selleck.cn/products/brigatinib-ap26113.html","C29H39ClN7O2P","Free Base","N/A","COC1=C(NC2=NC(=C(Cl)C=N2)NC3=CC=CC=C3[P](C)(C)=O)C=CC(=C1)N4CCC(CC4)N5CCN(C)CC5",5.084,6,2,8]
["S8548","Roblitinib (FGF401)","a3","L3800-54","in 2mM DMSO","N/A","N/A","Phase 1/2","FGFR","Protein Tyrosine Kinase","Roblitinib (FGF401) is an FGFR4-selective inhibitor with an IC50 of 1.9 nM. It binds in a reversible covalent manner to the FGFR4 kinase domain and shows at least 1,000 fold selectivity against of panel of 65 kinases in biochemical assays.",506.56,"1708971-55-4",{"v":5,"d":"5.00"},9.87,"<1","N/A","http://selleckchem.com/products/fgf401.html","C25H30N8O4","free base","N/A","COCCNC1=C(C=NC(=C1)NC(=O)N2CCCC3=C2N=C(C=O)C(=C3)CN4CCN(C)CC4=O)C#N",0.939,6,2,8]
["S8568","G1T38","b3","L3800-54","in 2mM DMSO","N/A","N/A","Phase 2","CDK","Cell Cycle","G1T38 (Lerociclib) is a novel, potent, selective, and orally bioavailable CDK4/6 inhibitor with IC50 values of 0.001 μM, 0.002 μM and 0.028 μM for CDK4, CDK6 and CDK9 respectively.",{"v":474.6,"d":"474.60"},"1628256-23-4",{"v":2,"d":"2.00"},4.21,"<1","N/A","http://www.selleck.cn/products/g1t38.html","C26H34N8O","free base","Lerociclib","CC(C)N1CCN(CC1)C2=CN=C(NC3=NC4=C(C=N3)C=C5[N]4C6(CCCCC6)CNC5=O)C=C2",4.087,4,2,4]
["S8724","Lazertinib","c3","L3800-54","in 2mM DMSO","N/A","N/A","Phase 2","EGFR","Protein Tyrosine Kinase","Lazertinib (YH25448,GNS-1480) is a potent, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively, showing much higher IC50 values aganist ErbB2 and ErbB4.",554.64,"1903008-80-9",{"v":4,"d":"4.00"},7.21,"<1","N/A","http://selleckchem.com/products/lazertinib-yh25448-gns-1480.html","C30H34N8O3","free base","YH25448,GNS-1480","COC1=CC(=C(NC(=O)C=C)C=C1NC2=NC=CC(=N2)[N]3C=C(CN(C)C)C(=N3)C4=CC=CC=C4)N5CCOCC5",{"v":4.56,"d":"4.560"},6,2,10]
["S5098","Gefitinib hydrochloride","d3","L3800-54","in 2mM DMSO","FDA,DMF,EMA,HMA,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,EP9.3,EP9.2,BP2017,IP2010","Marketed","EGFR","Protein Tyrosine Kinase","Gefitinib (ZD1839) is an EGFR inhibitor with IC50s of 15.5 nM and 823.3 nM for WT EGFR and EGFR (858R/T790M), respectively.",483.36,"184475-55-6","N/A",{"v":2,"d":"2.00"},{"v":1,"d":"1.00"},2.07,"http://selleckchem.com/products/gefitinib-hydrochloride.html","C22H24ClFN4O3.HCl","hydrochloride","ZD1839 hydrochloride","Cl.COC1=CC2=C(C=C1OCCCN3CCOCC3)C(=NC=N2)NC4=CC(=C(F)C=C4)Cl",4.585,5,1,8]
["S8927","GSK2983559 (compound 3)","e3","L3800-54","in 2mM DMSO","N/A","N/A","Phase 1","RIP kinase","Apoptosis","GSK2983559 (compound 3, RIP2 kinase inhibitor 1, RIPK2-IN-1) is a potent inhibitor of receptor interacting protein 2 (RIP2) kinase with good kinase specificity.",538.53,"1579965-12-0",{"v":5,"d":"5.00"},9.28,"<1","N/A","http://www.selleck.cn/products/gsk2983559-compound-3.html","C21H23N4O7PS2","Free Base","RIP2 kinase inhibitor 1, RIPK2-IN-1","CC(C)(C)[S](=O)(=O)C1=CC2=C(NC3=CC=C4SC=NC4=C3)N=CN=C2C=C1OCCO[P](O)(O)=O",3.391,7,1,9]
["S5031","Sulfaquinoxaline sodium","f3","L3800-54","in 2mM DMSO","DMF","Martindale:The Extra Pharmacopoeia","N/A","Parasite","Microbiology","Sulfaquinoxaline sodium (N'1-quinoxalin-2-ylsulphanilamide sodium, SQ-Na) is the sodium salt of sulfaquinoxaline, which is often used as a drug to prevent coccidiosis in poultry, swine, and sheep by inhibiting the synthesis of nucleic acids and proteins in microorganisms.",322.32,"967-80-6","N/A",{"v":2,"d":"2.00"},"N/A","N/A","http://selleckchem.com/products/sulfaquinoxaline-sodium.html","C14H11N4O2S.Na","sodium salt","SQ-Na","NC1=CC=C(C=C1)[S](=O)(=O)N([Na])C2=CN=C3C=CC=CC3=N2",1.677,4,1,3]
["S1502","Cephalexin","g3","L3800-54","in 2mM DMSO","FDA,NDC,DMF","USP42-NF37,IP2010","N/A","Antibiotics,Bacterial","Microbiology","Cephalexin (Cefalexin) is an antibiotic that can treat a number of bacterial infections.",347.39,"15686-71-2","N/A",{"v":2,"d":"2.00"},"N/A","N/A","http://selleckchem.com/products/Cephalexin-(Cefalexin).html","C16H17N3O4S","free base","Cefalexin","CC1=C(N2C(SC1)C(NC(=O)C(N)C3=CC=CC=C3)C2=O)C(O)=O",-2.255,3,2,4]
["S8875","MKC8866","h3","L3800-54","in 2mM DMSO","N/A","N/A","Phase 2","IRE1","ER stress & UPR","MKC8866 (IRE1-IN-8866), a salicylaldehyde analog, is a specific IRE1α RNase inhibitor with IC50 of 0.29 μM for human IRE1α in vitro.",361.35,"1338934-59-0",{"v":3,"d":"3.00"},{"v":8.3,"d":"8.30"},"˂1","N/A","http://www.selleckchem.com/products/mkc8866.html","C18H19NO7","Free Base","IRE1-IN-8866","COC1=C(O)C(=C2OC(=O)C(=C(C)C2=C1)CC(=O)N3CCOCC3)C=O",0.943,6,1,4]
["S0063","RG3039","a4","L3800-54","in 2mM DMSO","N/A","N/A","Phase 1","DNA/RNA Synthesis","DNA Damage/DNA Repair","RG3039 (PF-06687859, PF 6687859, Quinazoline 495) is an orally bioavailable and brain-penetrant inhibitor of the mRNA decapping enzyme DcpS with IC50 of 4.2 nM and IC90 of 40 nM, respectively.",432.35,"1005504-62-0",{"v":3,"d":"3.00"},6.94,"<1","N/A","https://www.selleckchem.com/products/rg3039.html","C21H23Cl2N5O","Free Base","PF-06687859, PF 6687859, Quinazoline 495","NC1=NC(=C2C(=CC=CC2=N1)OCC3CCN(CC3)CC4=C(Cl)C=CC=C4Cl)N",4.539,3,2,5]
["S6949","OTX008","b4","L3800-54","in 2mM DMSO","N/A","N/A","Phase 1","Galectin","Immunology & Inflammation","OTX008 (Calixarene 0118, PTX008), a calixarene derivative, is a selective inhibitor of galectin-1 (Gal1) with anti-tumoural activity.",937.18,"286936-40-1",{"v":3,"d":"3.00"},{"v":3.2,"d":"3.20"},"<1","N/A","https://www.selleckchem.com/products/otx008.html","C52H72N8O8","Free Base","Calixarene 0118, PTX-008","CN(C)CCNC(=O)COC1=C2CC3=CC=CC(=C3OCC(=O)NCCN(C)C)CC4=CC=CC(=C4OCC(=O)NCCN(C)C)CC5=CC=CC(=C5OCC(=O)NCCN(C)C)CC1=CC=C2",4.626,8,4,24]
["S4482","Palbociclib","c4","L3800-54","in 2mM DMSO","FDA, DMF, EMA, CFDA, NDC, PMDA","N/A","Marketed","CDK","Cell Cycle","Palbociclib (Ibrance, PD 0332991) is a highly specific inhibitor of cyclin-dependent kinase 4 (Cdk4) and Cdk6 with IC50 of 11 nM and 16 nM, respectively.",447.53,"571190-30-2",{"v":3,"d":"3.00"},{"v":6.7,"d":"6.70"},"<1","N/A","http://www.selleckchem.com/products/palbociclib.html","C24H29N7O2","Free Base","Ibrance, PD 0332991","CC(=O)C1=C(C)C2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2N(C5CCCC5)C1=O",2.801,5,2,5]
["S5799","Potassium guaiacolsulfonate hemihydrate","d4","L3800-54","in 2mM DMSO","CFDA","USP–NF 2021(Issue 2), KP Ⅹ, JP17","N/A","Others","Others","Potassium guaiacolsulfonate hemihydrate (Potassium Hydroxymethoxybenzenesulfonate, Sulfogaiacol) is used as an expectorant for relieving symptoms of cough and mucus in the chest due to respiratory infections, asthma, colds, or hay fever.",{"v":502.6,"d":"502.60"},"78247-49-1",{"v":5,"d":"5.00"},9.95,{"v":5,"d":"5.00"},9.95,"http://www.selleckchem.com/products/potassium-guaiacolsulfonate-hemihydrate.html","C14H16K2O11S2","Hemihydrate","Potassium Hydroxymethoxybenzenesulfonate, Sulfogaiacol","O.[K+].[K+].COC1=C(O)C=CC(=C1)[S]([O-])(=O)=O.COC2=C(O)C=CC(=C2)[S]([O-])(=O)=O",-2.889,2,2,4]
["E0161","Bictegravir Sodium","e4","L3800-54","in 2mM DMSO","FDA, EMA","N/A","Phase I","Integrase","Microbiology","Bictegravir (GS-9883) Sodium is a novel and potent inhibitor of HIV-1 integrase, specifically targets IN strand transfer activity with an IC50 of 7.5 nM.",473.38,"1807988-02-8",{"v":2,"d":"2.00"},4.22,"<1","N/A","http://www.selleckchem.com/products/bictegravir-sodium.html","C21H18F3N3O5.Na","Sodium","GS-9883 Sodium","[NaH].OC1=C2N(CC3OC4CCC(C4)N3C2=O)C=C(C(=O)NCC5=C(F)C=C(F)C=C5F)C1=O",{"v":0.65,"d":"0.650"},4,2,3]
["E0524","Spinosad","f4","L3800-54","in 2mM DMSO","FDA,NDC,DMF","N/A","Marketed","AChR,Anti-infection","Neuronal Signaling","Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete, is a biological neurotoxic insecticide with a broader action spectrum, targeting the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system.",731.96,"168316-95-8",{"v":3,"d":"3.00"},{"v":4.1,"d":"4.10"},"<1","N/A","http://www.selleckchem.com/products/spinosad.html","C41H65NO10","free base","N/A","NA","NA","NA","NA","NA"]
["S3309","Solasodine","g4","L3800-54","in 2mM DMSO","N/A","N/A","Phase 2","Akt,MicroRNA,MMP,PI3K","Proteases","Solasodine (Purapuridine, Solancarpidine, Solasodin, Salasodine, Salasdine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine reduces the mRNA level of matrix metalloproteinase-2 (MMP-2), MMP-9 and extracellular inducer of matrix metalloproteinase (EMMPRIN), but increases the expression of reversion-inducing cysteine-rich protein with kazal motifs (RECK). Solasodine downregulates oncogenic microRNA-21 (miR-21), which has been known to target RECK. Solasodine also reduces PI3K/Akt signaling pathways and downregulates expression of miR-21.",413.64,"126-17-0",{"v":2,"d":"2.00"},4.84,{"v":-1,"d":"-1.00"},"N/A","http://www.selleckchem.com/products/solasodine.html","C27H43NO2","free base","Purapuridine, Solancarpidine, Solasodin, Salasodine, Salasdine","CC1CCC2(NC1)OC3CC4C5CC=C6CC(O)CCC6(C)C5CCC4(C)C3C2C",4.367,1,2,0]
["S7178","Prexasertib HCl (LY2606368)","h4","L3800-54","in 2mM DMSO","NA","NA","Phase II","Chk","Cell Cycle","Prexasertib (LY2606368) is an ATP-competitive CHK1 inhibitor with a Ki value of 0.9 nmol/L. For CHK2 and RSK, its IC50 values are 8 nM and 9 nM respectively in cell-free assay.",438.31,"1234015-54-3",{"v":2,"d":"2.00"},4.56,"<1","N/A","http://www.selleckchem.com/products/ly2606368.html","C18H19N7O2.2HCl","dihydrochloride","N/A","Cl.Cl.COC1=CC=CC(=C1C2=CC(=N[NH]2)NC3=NC=C(N=C3)C#N)OCCCN",2.682,5,3,8]
["S3570","ARRY-382","a5","L3800-54","in 2mM DMSO","N/A","N/A","Phase 2","CSF-1R","Protein Tyrosine Kinase","ARRY-382 is a highly selective, oral inhibitor of the CSF1R with an IC50 of 9 nM.",564.68,"1313407-95-2",{"v":5,"d":"5.00"},8.85,"<1","N/A","http://www.selleckchem.com/products/arry-382.html","C32H36N8O2","Free base","N/A","CN1CCN(CCOC2=CC3=NC=C([N]3C=C2)C(=O)NC4=C5C(=CC=C4)[N](CC6=CC=CC(=N6)C)N=C5C7CC7)CC1",3.684,5,1,9]
["S6385","Prexasertib (LY2606368)","b5","L3800-54","in 2mM DMSO","N/A","N/A","Phase II","Chk,S6 Kinase","Cell Cycle","Prexasertib (LY2606368, ACR 368) is a selective ATP competitor inhibitor of Chk1 and Chk2 with IC50s of 1 nM and 8 nM in cell-free assays, respectively. Prexasertib also inhibits RSK1 with an IC50 of 9 nM in cell-free assay.",365.39,"1234015-52-1",{"v":3,"d":"3.00"},8.21,"<1","N/A","http://www.selleckchem.com/products/prexasertib-ly2606368.html","C18H19N7O2","Free base","ACR 368","COC1=C(C2=CC(=N[NH]2)NC3=CN=C(C=N3)C#N)C(=CC=C1)OCCCN",1.918,5,3,8]
["S9464","Tranylcypromine Sulfate","c5","L3800-54","in 2mM DMSO","FDA,NDC,DMF","USPNF 2022 Issue 1","Marketed","MAO","Metabolism","Tranylcypromine (Parnate) is an irreversible inhibitor of monoamine oxidase (MAO) with a rapid onset of activity.",364.46,"13492-01-8",{"v":2,"d":"2.00"},5.49,"<1","N/A","http://www.selleckchem.com/products/tranylcypromine-sulfate.html","C18H24N2O4S","Sulfate","Parnate","NC1CC1C2=CC=CC=C2.NC3CC3C4=CC=CC=C4.O[S;v6](O)(=O)=O",{"v":1.78,"d":"1.780"},0,2,2]
["S9872","AG-270","d5","L3800-54","in 2mM DMSO","N/A","N/A","Phase 1","MAT2A","Methylation","AG-270 is a potent and non-competitive methionine adenosyltransferase 2A (MAT2A) inhibitor which lessens the intracellular SAM levels  and MTAP-null–selective antiproliferative activity.",489.57,"2201056-66-6",{"v":3,"d":"3.00"},6.13,"<1","N/A","https://www.selleckchem.com/products/ag-270.html","C30H27N5O2","Free base","N/A","COC1=CC=C(C=C1)C2=C(NC3=CC=CC=N3)NC4=C(C5=CCCCC5)C(=N[N]4C2=O)C6=CC=CC=C6",6.837,4,2,6]
["E4160","Glycyl-L-tyrosine","e5","L3800-54","in 2mM DMSO","HMA, DMF","USP-NF2024, USP-NF2023, USP-NF2021","Marketed","Others","Natural Products","Glycyl-L-tyrosine is a dipeptide containing glycine and L-tyrosine. It is an amino acid inhibitor from potatoes.",238.24,"658-79-7","N/A",">2","N/A","N/A","https://www.selleckchem.com/products/glycyl-l-tyrosine.html","C11H14N2O4","free base","Gly-Tyr","NCC(=O)NC(CC1=CC=C(O)C=C1)C(O)=O",-2.787,2,3,5]
["E4468","Cabotegravir Sodium","f5","L3800-54","in 2mM DMSO","FDA;NDC;PMDA;DMF","N/A","marketed","Integrase","Microbiology","Cabotegravir (GSK-1265744) sodium is a orally active and long-acting HIV integrase strand transfer inhibitor. It also inhibits organic anion transporter 1/3 (OAT1/OAT3) with IC50 of 0.41 μM and 0.81 μM for OAT3 and OAT1, respectively.",428.34,"1051375-13-3",{"v":2,"d":"2.00"},4.67,"<1","N/A","https://www.selleckchem.com/products/cabotegravir-sodium.html","C19H17F2N3O5.Na","sodium salt","GSK-1265744 sodium","[Na;v0].CC1COC2CN3C=C(C(=O)NCC4=C(F)C=C(F)C=C4)C(=O)C(=C3C(=O)N12)O",0.237,4,2,3]
["S2544","Cefprozil hydrate","g5","L3800-54","in 2mM DMSO","HMA,FDA,NDC,DMF,CFDA","BP2024;USP-NF2024;EP11.0;Martindale: The Complete Drug Reference","Marketed","Bacterial","Microbiology","Cefprozil hydrate is a semi-synthetic broad-spectrum cephalosporin <b>antibiotic</b>, used to treat certain infections caused by bacteria, such as bronchitis and infections of the ears, throat, sinuses, and skin.",407.44,"121123-17-9","N/A",">2","N/A","N/A","https://www.selleckchem.com/products/Cefprozil-hydrate-Cefzil.html","C18H19N3O5S.H2O","Free base","N/A","[OH2:29].[CH3:12]/[CH:11]=[CH:10]/[C:20]1=[C:16]([N:14]2[CH:15]([S:19][CH2:21]1)[CH:18]([NH:5][C:6](=[O:8])[CH:7]([NH2:9])[C:22]3=[CH:23][CH:25]=[C:27]([OH:13])[CH:26]=[CH:24]3)[C:17]2=[O:4])[C:1]([OH:2])=[O:3]",-2.236,3,{"v":3,"d":"3.000"},5]
["S1346","Heparin sodium","a2","L3800-55","in 2mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,EP9.3,KP Ⅹ,EP9.1,JP17,BP2017,Ph.Int_5th,IP2010","Marketed","Autophagy,Factor Xa,Thrombin","Proteases","Heparin sodium, a sulfated polysaccharide belonging to the family of glycosaminoglycans, has numerous important biological activities associated with its interaction with diverse proteins. Heparin is used as an anticoagulant primarily through its interaction with AT III by enhancing AT-IIImediated inhibition of blood coagulation factors, including thrombin and factor Xa. Heparin prevents the induction of autophagy.","6000-20000","9041-08-1","<1","N/A",{"v":100,"d":"100.00"},{"v":8,"d":"8.00"},"http://selleckchem.com/products/Heparin-sodium.html","(C12H16NS2Na3)20","Sodium salt","N/A","CCC1CC(N[R])C(OC1CO[S]([O-])(=O)=O)OC2C(O)C(O)C(OC3C(CO[R])OC(OC4C(O)C(O[S]([O-])(=O)=O)C(OC5C(O)C(N[S]([O-])(=O)=O)C(C)OC5CO[S]([O-])(=O)=O)OC4C([O-])=O)C(N[S]([O-])(=O)=O)C3[S]([O-])(=O)=O)OC2C([O-])=O",-22.565,13,7,27]
["S1428","Risedronate Sodium","b2","L3800-55","in 2mM Water","FDA,DMF,CFDA,NDC,HMA","Martindale:The Extra Pharmacopoeia,USP39-NF34","Marketed","Others","Metabolism","Risedronate (NE 58095) sodium, a nitrogen-containing bisphosphonate, inhibits osteoclast-mediated bone resorption and modulates bone metabolism, used in the treatment of osteoporosis.",305.09,"115436-72-1","<1","N/A",{"v":2,"d":"2.00"},6.56,"http://selleckchem.com/products/Risedronate-sodium.html","C7H10NNaO7P2","Sodium salt","NE 58095 Sodium","[Na+].OC(CC1=CC=CN=C1)([P](O)(O)=O)[P](O)([O-])=O",-1.737,1,0,4]
["S1911","Disodium Cromoglycate","c2","L3800-55","in 2mM Water","DMF,HMA","N/A","Phase 2","Calcium Channel","Transmembrane Transporters","Disodium Cromoglycate (Gynazole ,FPL 670 (Cromolyn) Disodium,Cromolyn sodium) is an antiallergic drug with IC50 of 39 μg/mL.",512.33,"15826-37-6","<1","N/A",{"v":2,"d":"2.00"},{"v":3.9,"d":"3.90"},"http://selleckchem.com/products/disodium-Cromoglycate.html","C23H14O11.2Na","Disodium Salt","Gynazole ,FPL 670 (Cromolyn) Disodium,Cromolyn sodium","[Na+].[Na+].OC(COC1=C2C(=O)C=C(OC2=CC=C1)C([O-])=O)COC3=CC=CC4=C3C(=O)C=C(O4)C([O-])=O",-1.178,6,1,8]
["S1982","Adenine sulfate","d2","L3800-55","in 2mM Water","DMF,NDC,PMDA","USP42-NF37","N/A","DNA/RNA Synthesis","DNA Damage/DNA Repair","Adenine sulfate(Adenine hemisulfate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.",368.33,"321-30-2","<1","N/A",{"v":2,"d":"2.00"},5.43,"http://selleckchem.com/products/adenine-sulfate.html","2(C5H5N5).H2SO4","Sulfate","Adenine hemisulfate","NC1=NC=NC2=C1[NH]C=N2.NC3=NC=NC4=C3[NH]C=N4.O[S](O)(=O)=O",-1.498,6,4,0]
["S2106","Azasetron HCl","e2","L3800-55","in 2mM Water","CFDA,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor","Neuronal Signaling","Azasetron HCl (Y-25130) is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.",386.27,"123040-16-4","<1","N/A",{"v":3,"d":"3.00"},7.77,"http://selleckchem.com/products/azasetron-hcl.html","C17H20ClN3O3.HCl","HCl","Y-25130 HCl","Cl.CN1C(=O)COC2=C(C=C(Cl)C=C12)C(=O)NC3CN4CCC3CC4",1.616,3,1,2]
["S2562","Hydralazine HCl","f2","L3800-55","in 2mM Water","FDA,DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,USP42-NF37,EP9.2,KP Ⅹ,Ph.Int_6th,JP17,BP2017,IP2010","N/A","Potassium Channel","Transmembrane Transporters","Hydralazine HCl is a hydrochloride salt of hydralazine, which is a direct-acting smooth muscle relaxant used to treat hypertension by acting as a vasodilator primarily in arteries and arterioles.",196.64,"304-20-1","<1","N/A",{"v":1,"d":"1.00"},5.09,"http://selleckchem.com/products/Hydralazine-hydrochloride.html","C8H8N4.HCl","Hydrochloride","N/A","Cl.N/N=C/1NN=CC2=C1C=CC=C2",0.798,2,2,0]
["S3055","Besifloxacin HCl","g2","L3800-55","in 2mM Water","FDA,DMF,NDC","N/A","Marketed","Antibiotics","Microbiology","Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic.",{"v":430.3,"d":"430.30"},"405165-61-9","<1","N/A",{"v":1,"d":"1.00"},2.32,"http://selleckchem.com/products/besifloxacin-hci.html","C19H21ClFN3O3.HCl","Hydrochloride","N/A","Cl.NC1CCCCN(C1)C2=C(Cl)C3=C(C=C2F)C(=O)C(=CN3C4CC4)C(O)=O",0.698,2,1,3]
["S3749","Calcium gluconate monohydrate","h2","L3800-55","in 2mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.1,Ph.Int_6th,JP17,BP2017,IP2010","Phase 2","Others","Others","Calcium gluconate (Calcarea gluconica, Calcium gluconate anhydrous, Calcium D-gluconate, Calciofon, Glucobiogen) is element or mineral necessary for normal nerve, muscle, and cardiac function. Calcium as the gluconate salt helps to maintain calcium balance and prevent bone loss when taken orally.",448.39,"66905-23-5","<1","N/A",{"v":4,"d":"4.00"},8.92,"http://selleckchem.com/products/calcium-gluconate.html","C12H22O14.Ca.H2O","monohydrate","Calcarea gluconica, Calcium gluconate anhydrous, Calcium D-gluconate, Calciofon, Glucobiogen","O.[Ca++].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O",-8.781,0,10,10]
["S4067","Deferiprone","a3","L3800-55","in 2mM Water","FDA,DMF,EMA,HMA,NDC","Martindale:The Extra Pharmacopoeia,EP9.5","Marketed","Others","Others","Deferiprone (CP20) is a chelating agent with an affinity for ferric ion (iron III)，binds with ferric ions to form neutral 3:1 (deferiprone:iron) complexes that are stable over a wide range of pH values.",139.15,"30652-11-0","<1","N/A",{"v":1,"d":"1.00"},7.19,"http://selleckchem.com/products/deferiprone.html","C7H9NO2","Free Base","CP20","CN1C=CC(=O)C(=C1C)O",-0.139,1,1,0]
["S4153","D-Phenylalanine","b3","L3800-55","in 2mM Water","DMF","Martindale:The Extra Pharmacopoeia,USP42-NF37,KP Ⅹ,EP9.2,JP17,BP2017","N/A","Others","Endocrinology & Hormones","D-Phenylalanine, a carboxypeptidase A, endorphinase and enkephalinase inhibitor, enhances endorphin production and diminishes pain.",165.19,"673-06-3","<1","N/A",{"v":1,"d":"1.00"},6.05,"http://selleckchem.com/products/d-phenylalanine.html","C9H11NO2","Free Base","N/A","NC(CC1=CC=CC=C1)C(O)=O",-1.605,1,1,3]
["S4226","Minocycline (CL 59806) HCl","c3","L3800-55","in 2mM Water","FDA,DMF,CFDA,NDC,PMDA,HMA","Martindale:The Extra Pharmacopoeia,CP2005,USP42-NF37,KP Ⅹ,EP9.1,JP17,BP2017","Marketed","Antibiotics","Microbiology","Minocycline (CL 59806,Minocin) HCl is the most lipid soluble and most active tetracycline antibiotic, binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis.",493.94,"13614-98-7","<1","N/A",{"v":1,"d":"1.00"},2.02,"http://selleckchem.com/products/minocycline-hcl.html","C23H27N3O7.HCl","Hydrochloride","Minocin","Cl.CN(C)C1C2CC3CC4=C(C(=CC=C4N(C)C)O)C(=O)C3=C(O)C2(O)C(=O)C(=C1O)C(N)=O",{"v":0,"d":"0.000"},0,0,0]
["S4694","Alosetron Hydrochloride","d3","L3800-55","in 2mM Water","FDA,DMF,NDC","Martindale:The Extra Pharmacopoeia","Marketed","5-HT Receptor","Neuronal Signaling","Alosetron Hydrochloride (GR 68755C, GR 68755X, Lotronex) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist.",330.81,"122852-69-1","<1","N/A",{"v":1,"d":"1.00"},3.02,"http://selleckchem.com/products/alosetron-hydrochloride.html","C17H18N4O.HCl","hydrochloride","GR 68755C, GR 68755, GR 68755X, Lotronex, GR-68755, GR68755","Cl.C[N]1C2=C(C(=O)N(CC2)CC3=C(C)N=C[NH]3)C4=C1C=CC=C4",2.036,2,1,2]
["S5355","Piperaquine phosphate","e3","L3800-55","in 2mM Water","CFDA","Martindale:The Extra Pharmacopoeia","Marketed","Anti-infection","Microbiology","Piperaquine phosphate is an orally active bisquinolone antimalarial drug.",633.51,"85547-56-4","<1","N/A",{"v":2,"d":"2.00"},3.16,"http://selleckchem.com/products/piperaquine-phosphate.html","C29H32Cl2N6.H3O4P","phosphate","N/A","O[P](O)(O)=O.ClC1=CC=C2C(=C1)N=CC=C2N3CCN(CCCN4CCN(CC4)C5=C6C=CC(=CC6=NC=C5)Cl)CC3",5.012,2,0,6]
["S5695","Icatibant Acetate","f3","L3800-55","in 2mM Water","DMF,EMA,NDC,FDA,marketed in Japan","Martindale:The Extra Pharmacopoeia","Marketed","Bradykinin Receptor","GPCR & G Protein","Icatibant Acetate(HOE-140 acetate) acts as an antagonist of the bradykinin B2 receptor and is used in the treatment of hereditary angioedema.",1364.57,"138614-30-9",{"v":-1,"d":"-1.00"},"N/A",{"v":11,"d":"11.00"},8.06,"http://www.selleckchem.com/products/icatibant-acetate.html","C61H93N19O15S","Acetate","HOE-140 acetate","CC(O)=O.NC(CCCNC(N)=N)C(=O)NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)N2CC(O)CC2C(=O)NCC(=O)NC(CC3=CC=CS3)C(=O)NC(CO)C(=O)N4CC5=C(CC4C(=O)N6C7CCCCC7CC6C(=O)NC(CCCNC(N)=N)C(O)=O)C=CC=C5",-6.943,11,14,33]
["S8030","Plerixafor (AMD3100)","g3","L3800-55","in 2mM Water","FDA,DMF,EMA,NDC,PMDA","Martindale:The Extra Pharmacopoeia","Marketed","CXCR,HIV","GPCR & G Protein","Plerixafor (AMD3100, JM 3100, SID791) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively. Plerixafor inhibits human immunodeficiency virus (HIV) replication.",502.78,"110078-46-1","<1","N/A",{"v":3,"d":"3.00"},5.97,"http://selleckchem.com/products/plerixafor.html","C28H54N8","Free Base","JM 3100, SID791","C1CNCCNCCCN(CCNC1)CC2=CC=C(CN3CCCNCCNCCCNCC3)C=C2",{"v":-0.52,"d":"-0.520"},0,6,4]
["S5650","Sodium Hyaluronate","h3","L3800-55","in 2mM Water","DMF,CFDA,NDC,PMDA","Martindale:The Extra Pharmacopoeia,KP Ⅹ,EP9.1,BP2017,IP2010","Marketed","Others","Others","Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan found in various connective tissue of humans.",{"v":401.3,"d":"401.30"},"9067-32-7","The physical form of the compound is liquid, which can be dissolved in any proportion.","N/A","N/A",{"v":2,"d":"2.00"},"https://www.selleckchem.com/products/sodium-hyaluronate.html","C14H20NNaO11R","free base","N/A","[Na+].CC(=O)NC1C(C(O)C(CO)OC1OC2C(O)C(O)C(O[*])OC2C([O-])=O)[*]",-4.314,5,5,6]
["S2095","Fosinopril Sodium","a4","L3800-55","in 2mM Water","FDA,DMF,CFDA,NDC,HMA","EP9.1,BP2017,USP39-NF34","Marketed","ACE,RAAS","Endocrinology & Hormones","Fosinopril Sodium (SQ28555) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.",585.64,"88889-14-9","N/A","N/A","N/A",{"v":2,"d":"2.00"},"http://selleckchem.com/products/fosinopril-sodium-monopril.html","C30H45NO7P.Na","Sodium Salt","SQ28555","[Na+].CCC(=O)OC(O[P](=O)(CCCCC1=CC=CC=C1)CC(=O)N2CC(CC2C([O-])=O)C3CCCCC3)C(C)C",4.129,5,0,15]
["S2050","Strontium Ranelate","b4","L3800-55","in 2mM Water","FDA,EMA,HMA,CFDA,PMDA,NDC,DMF","USPNF 2022 Issue 1,EP10.8","Marketed","Calcium Channel","Transmembrane Transporters","Strontium Ranelate is a strontium(II) salt of ranelic acid for (-)-desmethoxyverapamil binding to calcium channel with IC50 of 0.5 mM.",513.49,"135459-87-9","<1","N/A",{"v":2,"d":"2.00"},3.89,"http://www.selleckchem.com/products/strontium-ranelate-protelos.html","C12H6N2O8S.2Sr","Free base","N/A","O=C1CN(CC(=O)O[Sr]O1)C2=C(C#N)C3=C(S2)C(=O)O[Sr]OC(=O)C3",0.569,8,0,1]
["S5264","L-5-Methyltetrahydrofolate calcium","c4","L3800-55","in 2mM Water","DMF,NDC","USP-NF2024","Marketed","Others","Others","Calcium L-5-methyltetrahydrofolate (L-5-MTHF-Ca) is a synthetic derivative of folic acid, the predominant, naturally occurring form of folate.",497.52,"151533-22-1","<1","N/A",{"v":1,"d":"1.00"},2.01,"http://www.selleckchem.com/products/l-5-methyltetrahydrofolate-calcium.html","C20H23N7O6.Ca","Calcium salt","L-5-MTHF-Ca","[Ca++].CN1C(CNC2=CC=C(C=C2)C(=O)NC(CCC([O-])=O)C([O-])=O)CNC3=C1C(=O)NC(=N3)N",-3.742,3,5,9]
["S4444","Hypromellose","a2","L3800-56","in 2mg/ml DMSO","NDC, HMA, DMF","JP18, BP2023, USP-NF2024","Marketed","others","others","Hypromellose (Hydroxypropyl Methyl Cellulose, HPMC, Celacol HPM 5000) is a commonly employed cellulose ether used in the fabrication of hydrophilic matrices. Hypromellose provides the release of a drug in a controlled manner, effectively increasing the duration of release of a drug to prolong its therapeutic effect.","N/A","9004-65-3",{"v":100,"d":"100.00"},"N/A",{"v":100,"d":"100.00"},"N/A","https://www.selleckchem.com/products/hypromellose.html","N/A","Free Base","Hydroxypropyl Methyl Cellulose, HPMC, Celacol HPM 5000, Hydroxypropylmethyl cellulose","N/A","N/A","N/A","N/A","N/A"]
["S3505","Polidocanol","b2","L3800-56","in 2mg/ml DMSO","FDA, NDC, PMDA","N/A","Marketed","others","others","Polidocanol (Polyoxyethylene lauryl ether, Polyoxyethyleneglycol Dodecyl Ether, Brij30, Laureth-23, Varithena) is a sclerosant used for treating uncomplicated spider veins and reticular veins in the lower extremities.","N/A","9002-92-0",{"v":100,"d":"100.00"},"N/A",{"v":100,"d":"100.00"},"N/A","https://www.selleckchem.com/products/polidocanol.html","(C2H4O)nC12H26O","Free Base","Polyoxyethylene lauryl ether, Polyoxyethyleneglycol Dodecyl Ether, Brij30, Laureth-23, Varithena","CCCCCCCCCCCCOCCO",4.489,1,1,13]