ub ub Frizzled Frizzled Frizzled MKK3/6 cGMP IP 3 Cdc42 Cdc42 MKK7 Actin Cytoskeleton,Cell Adhesion DAG XRNF 185 Daam1 Paxillin Profilin TK WIF Fer WTX p120 MRLC PIP 2 PKG TAK1 NLK Ca 2+ CNA GMP Dvl Naked PAR-1 DKKs SFRP CYLD CK1ε Axin PAR-1 Activated Canonical Wnt Signaling Activated Non-canonical Inactivated Wnt Signaling sFRP Ror2 Cadherin Dvl GeneExpression PP2A β-TrCP ATF2 NFAT ATF2 TCF1 UbC4 Gastrin NRSF ENC1 c-Jun NRCAM Cldn1 FRA1 Cell Fate:Proliferation,Differentiation,Adhesion andSurvival Cell Fate:Proliferation,Differentiation,Adhesion andSurvival uPAR CyclinD1 Vimentin β-TrCP c-Jun DvI Axin CK1ε Dvl Dvl GBP Chibby LEF/TCF RAR ICAT PYGO CBP RA BCL9 α-catenin LRP5/6 LRP5/6 P {{ board.text }} {{ board.text }} {{ board.text }} {{ board.text }} {{ board.text }} {{ board.text }} {{ group.title }} {{ text.text }} {{ button.text }} {{ group.title }} {{ text.text }}