cAMP
PI3K
Smo
5HT2B
Glutamate
ET1
5HT1D
Akt
Hedgehog
JAK
STAT
PI3K
Akt
MEKs
mTOR
IKKs
NF-κB
p70S6K
Ras
Raf
MEKs
ERK
PKA
PAK
p38
Rac
PI3K
Src
Src
Src
Ras
GEFs
ROCK
PKA
MEKs
ERK
GEFs
PKC
ROCK
Raf
ERK
MEKs
Thrombin
AC
αi
βγ
αq
βγ
αs
βγ
αi
βγ
α12
βγ
SOS
GRB2
SHC
GLI
CDC42
PLCβ
IP
3
AC
Rho
β-arrestin
DAG
GEFs
Rho
PTC
MMPs
GPCR
HB-EGF
EGFR
cAMP
Ca
2+
Transcription Factors
Gene Expression
Proliferation, Survival, Invasion,Migration, Angiogenesis
Smoothened AntagonistsCyclopamineSonidegibSmoothened AgonistsSmoothened Agonist (SAG)Purmorphamine
5-HT Receptor InhibitorsVortioxetineRS-127445FluoxetineSertraline5-HT Receptor ActivatorsSerotoninPimavanserinTianeptine Sodium
Endothelin ReceptorAntagonistsMacitentanBQ-123Bosentan
cAMP ActivatorForskolincAMP InhibitorSQ22536
P
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MMPs
PTC
HB-EGF
cAMP
Ca
2+
Transcription Factors
Gene Expression
Proliferation, Survival, Invasion,
Migration, Angiogenesis
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Notes:
1:Clickable
2:Unclickable